<?xml version="1.0" encoding="UTF-8"?>
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<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVH9</accession>
    <name>D0YVH9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">5'-deoxynucleotidase VDA_001559</fullName>
            <ecNumber evidence="1">3.1.3.89</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">5'-deoxyribonucleotidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Nucleoside 5'-monophosphate phosphohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001559</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the strictly specific dephosphorylation of 2'-deoxyribonucleoside 5'-monophosphates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxyribonucleoside 5'-phosphate + H2O = a 2'-deoxyribonucleoside + phosphate</text>
            <dbReference type="Rhea" id="RHEA:36167"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:18274"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:65317"/>
            <dbReference type="EC" id="3.1.3.89"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the 5DNU family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.89" evidence="1"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298277.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001559"/>
    <dbReference type="EnsemblBacteria" id="EEZ40533">
        <property type="protein sequence ID" value="EEZ40533"/>
        <property type="gene ID" value="VDA_001559"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1896">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1508841at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01100">
        <property type="entry name" value="5DNU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022971">
        <property type="entry name" value="YfbR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD" evidence="2">
        <location>
            <begin position="30"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="1">
        <location>
            <begin position="18"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="1">
        <location>
            <begin position="77"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="33"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="69"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="137"/>
        </location>
    </feature>
    <feature type="site" description="Appears to be important in orienting the phosphate for catalysis" evidence="1">
        <location>
            <position position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="194" mass="22336" checksum="C3397EEE3057F297" modified="2010-01-19" version="1">MKQSHFFAHLARMKLIQRWPLMRCVSSENISEHSLQVAFVAHALALIKNRKFNGTTNPEKIALLGLFHDCSEVLTGDMPTPIKYYNPAIAEEYKKIELAAEQKLLSMLPEEFHQDYAPLLDSHYIDPDDYHIVKQADSLCAYLKCLEELNAGNHEFAQAKKRLEETLAARETPEMRYFLETFAQSFTLTLDEIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVV2</accession>
    <name>D0YVV2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002033</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299232.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002033"/>
    <dbReference type="EnsemblBacteria" id="EEZ41001">
        <property type="protein sequence ID" value="EEZ41001"/>
        <property type="gene ID" value="VDA_002033"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1679623at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="171" mass="19749" checksum="1D0E2CD37B972C39" modified="2010-01-19" version="1">MVAKIKTKSFCFGGVRFIPENRQITWDKDKSCFLSEHENRLLCTLCSCAGEVVSIQTLYQKTFIEIDPFEDCDQQYDLNLLLMALSKKLNYRGQMLIPIHVIPSFGYRVPLPHRKPQSTHNPILQKAFPLTQNESDTVSCINLVKFCQQHKKPVLISVFLLILFVLFTKII</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVZ3</accession>
    <name>D0YVZ3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Enolase</fullName>
            <ecNumber evidence="8">4.2.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">2-phospho-D-glycerate hydro-lyase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">2-phosphoglycerate dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">eno</name>
        <name evidence="13" type="ORF">VDA_001272</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:10164"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58289"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="4.2.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="8">The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 4/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Secreted</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Cell surface</location>
        </subcellularLocation>
        <text evidence="8">Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the enolase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.11" evidence="8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297759.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001272"/>
    <dbReference type="EnsemblBacteria" id="EEZ40250">
        <property type="protein sequence ID" value="EEZ40250"/>
        <property type="gene ID" value="VDA_001272"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0148">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="533698at2"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00187"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000015">
        <property type="term" value="C:phosphopyruvate hydratase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004634">
        <property type="term" value="F:phosphopyruvate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03313">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00318">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000941">
        <property type="entry name" value="Enolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020810">
        <property type="entry name" value="Enolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020809">
        <property type="entry name" value="Enolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020811">
        <property type="entry name" value="Enolase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11902">
        <property type="entry name" value="PTHR11902"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00113">
        <property type="entry name" value="Enolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03952">
        <property type="entry name" value="Enolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001400">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00148">
        <property type="entry name" value="ENOLASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00002">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01192">
        <property type="entry name" value="Enolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01193">
        <property type="entry name" value="Enolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="SSF51604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="SSF54826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01060">
        <property type="entry name" value="eno"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00164">
        <property type="entry name" value="ENOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="7 8 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Enolase_N" evidence="12">
        <location>
            <begin position="4"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Enolase_C" evidence="11">
        <location>
            <begin position="143"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8 10">
        <location>
            <begin position="370"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8 9">
        <location>
            <position position="209"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8 9">
        <location>
            <position position="343"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="291"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="318"/>
        </location>
    </feature>
    <feature type="binding site" description="covalent; in inhibited form" evidence="8">
        <location>
            <position position="343"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="394"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001400-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001400-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ40250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="433" mass="45843" checksum="DB715F42D46B133F" modified="2010-01-19" version="1">MSKIVKILGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVLKAVTAVNGPIAEALLGKDAKDQAAIDQIMIDLDGTENKSNFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTAGQFSMPLPMMNILNGGEHADNNVDIQEFMIQPVGAKTLKEALRIGAEVFHNLAKVLKSKGMSTAVGDEGGFAPNLSSNAEALAVIKEAVEAAGYELGKDVTLAMDCAASEFYNKEEGIYDLKGEGKKFTSEEFNHFLAELVDQYPIVSIEDGLDESDWDGFAHQTKLLGDKIQLVGDDLFVTNTKILAEGIEKNIVNSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGERAPFNGLKEVKGQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW00</accession>
    <name>D0YW00_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SLT_4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001305</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297838.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001305"/>
    <dbReference type="EnsemblBacteria" id="EEZ40280">
        <property type="protein sequence ID" value="EEZ40280"/>
        <property type="gene ID" value="VDA_001305"/>
    </dbReference>
    <dbReference type="GeneID" id="57339803"/>
    <dbReference type="eggNOG" id="COG4764">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1391625at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045795">
        <property type="entry name" value="SLT_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19489">
        <property type="entry name" value="SLT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018680" description="SLT_4 domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="SLT_4" evidence="2">
        <location>
            <begin position="9"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="203" mass="23823" checksum="193749E827AB1C7D" modified="2010-01-19" version="1">MISPPRLIVFIALALALTGCATPPPKNQSNICSIFRENPDWYKDAVKMEKKWGTPIHVAMAIIKQESSFRHDARPPKDYVLGFIPWGRVSSAYGYAQAQDPAWEDFQRATNNGGSRTDFYDSLQFVGWYTYETQRQLGISKWDAYRQYLAYHEGRGGYQRGTYRRKPNLMQVARKVDRYSKEYGWQLKQCRQELESKRSWWPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW47</accession>
    <name>D0YW47_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Probable glutamate/gamma-aminobutyrate antiporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_001329</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001329"/>
    <dbReference type="EnsemblBacteria" id="EEZ40304">
        <property type="protein sequence ID" value="EEZ40304"/>
        <property type="gene ID" value="VDA_001329"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0531">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022520">
        <property type="entry name" value="Glu/GABA_antiporter_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03813">
        <property type="entry name" value="put_Glu_GABA_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="85"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="130"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="160"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="203"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="236"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="288"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="341"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="368"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="412"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="445"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="508" mass="55233" checksum="8E88ECC8411FABF2" modified="2010-01-19" version="1">MANLNSANKKGISIFALAMLNIVAVVSLRGLPAEAEYGLSSIFYYIFAAVVFLVPVSLVAAELATGWSEKGGVFRWVGEAFGPRFALIAMFMLWIEVTVWFPTALTFGSVSLAFVGPDQTWDQALSQNKFFVLGIVLAIYWIATFIALHGTEAFSKVAKWGGMIGTVIPGIILIVLGFSYVFAGNTPQIDLSWDKVIPDFTNFNNVVLAASIFLFYAGMEMNAIHVKEVDDAPRNYPIAIAIAAIGTVCVFVLGTLAIAFVIPQKDINLTQSLLVAYDDMFAWAGISWAAPIMAACLALGVLAGVVGWVAGPSSGLLVVAKGGYLPRFWQYTNKHGMATHIMLAQALLVTLISTVFVVLPSVQAAYQILSQLTVVLYLIMYLLMFAAAIHLRYSQPNRPRPYRIPGKENSGMWLIGGLGFIGSLTAFLFSFIPPSQISVGSPAEYVGFLVVLTVVFVSVPLFIYKARKPHWKDPAVTDFAPFTWEIEDIHPGVINPSDKATHTLHNAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW78</accession>
    <name>D0YW78_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphatidate cytidylyltransferase</fullName>
            <ecNumber evidence="7">2.7.7.41</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_001363</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a 1,2-diacyl-sn-glycero-3-phosphate + CTP + H(+) = a CDP-1,2-diacyl-sn-glycerol + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:16229"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
            <dbReference type="ChEBI" id="CHEBI:58608"/>
            <dbReference type="EC" id="2.7.7.41"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the CDS family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.41" evidence="7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297925.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001363"/>
    <dbReference type="EnsemblBacteria" id="EEZ40338">
        <property type="protein sequence ID" value="EEZ40338"/>
        <property type="gene ID" value="VDA_001363"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4589">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1533756at2"/>
    <dbReference type="UniPathway" id="UPA00557">
        <property type="reaction ID" value="UER00614"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004605">
        <property type="term" value="F:phosphatidate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016024">
        <property type="term" value="P:CDP-diacylglycerol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000374">
        <property type="entry name" value="PC_trans"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01315">
        <property type="entry name" value="CDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="86"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="120"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="152"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="191"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="214"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="264"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ40338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="282" mass="30552" checksum="35061B9B907444D8" modified="2010-01-19" version="1">MLKQRIITALILAPLVIAGIFFLPFSAFMIAIAAISLIGFWEWTQFVEAKSRIQAMIIPVVALGLSMLALPINYQSMATLSASHHGMLLIGGIWWLIASILALTYPASTSLWSKAPPLKHLFGLLTLIPFFWSILLLRAVNYEVDSTHGAKLVLLVCLIVWAADTGAYFSGKRFGKHKMAPAVSPNKTLEGLAGGVILAVFVAWGGAHIMSIPFYSVASLLTIAVITVISSVLGDLVESMFKRVSGIKDSGNILPGHGGILDRIDSLTAAFPIFALLYLWWM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWL4</accession>
    <name>D0YWL4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Caps_synth_GfcC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001505</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298175.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001505"/>
    <dbReference type="EnsemblBacteria" id="EEZ40479">
        <property type="protein sequence ID" value="EEZ40479"/>
        <property type="gene ID" value="VDA_001505"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5030EE4">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1742591at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010425">
        <property type="entry name" value="Caps_synth_GfcC-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06251">
        <property type="entry name" value="Caps_synth_GfcC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019770" description="Caps_synth_GfcC domain-containing protein" evidence="1">
        <location>
            <begin position="29"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="Caps_synth_GfcC" evidence="2">
        <location>
            <begin position="43"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="272" mass="30767" checksum="33A487272E893992" modified="2010-01-19" version="1">MNITKNPLSSLCKIAVLVALITSNNVLAKTETSPTDNPSQQAALAVELLTSNSNTPITLNYSSPVRLDHVIHDGWQQFTIQHPNQMPYWLGSDLVELRSPKNKTYTLSLLNTLALDQDNPYALRQSAKHLSAWLNQNVVHRRLWQNLDYDFVRLNIANNPQLQGSYQLVLPTTPNKVLVLGAVATPTEVMWQPRISAAELLTQVNVIDEHNRSQISVIQPDGQIETHSIAYWNQNHKDIAPGATLYVHYEQAFDLHRDLNQFVIQLLQNRTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWW4</accession>
    <name>D0YWW4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidyl-prolyl cis-trans isomerase PpiD</fullName>
            <ecNumber evidence="3">5.2.1.8</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001553</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="5.2.1.8" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001553"/>
    <dbReference type="EnsemblBacteria" id="EEZ40527">
        <property type="protein sequence ID" value="EEZ40527"/>
        <property type="gene ID" value="VDA_001553"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0760">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000297">
        <property type="entry name" value="PPIase_PpiC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027304">
        <property type="entry name" value="Trigger_fact/SurA_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109998">
        <property type="entry name" value="SSF109998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50198">
        <property type="entry name" value="PPIC_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PpiC" evidence="2">
        <location>
            <begin position="203"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="565" mass="62655" checksum="96FBE8DD2FC6E012" modified="2010-01-19" version="1">MQAQLGENFSNLLGNPQYVQQFRRSVLERMINDVLIQKRAHELGLRVSDQQIRDAIFAMPEFKVDGKFNNEQYNQLLRRSGITPEQFAESLRTDLLRQQFLGAIEGSDFALSGEVNELRMLESQERVIRTLTLNLADFTKKAEASITEEQEKAFYEQNPQQFTRPAQVKVSYVEITGDKLKDSIEVSDAQAYYNEHKDKFSTPEKRQVSHILITGDSAASKEKAEAILAQLKDGANFAELAKKDSDDKFSAKDGGKLEWFEKGVMDPAFEDAAFALAKPGDLSGVVKSSFGYHIILLDGIEPAKAKPFADVKAEIIADIKSQKAGDEFYAMQTKLAETAFESPDSLDEAAEAVKAKVHATDFFSEQTAPGVLNNPKVLQALQSPEVREDGMNSDAIEVGPEHVVVVRVDDARDETVLPFKDVEAKVKSLLAQRDGEQQAQKKADELVAQLRDGKSEQLTKEGYSFSGEQTITRSGPDYQVSQVAFRLAKPQAGKATYGVTRDAKGNVLIVQLDKVIDQDVAKEAADPQFAQQVEQMNAQQDMATTIQTLRETADISTPVLEQSTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWX4</accession>
    <name>D0YWX4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Peptide transport system ATP-binding protein SapF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001807</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298740.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001807"/>
    <dbReference type="EnsemblBacteria" id="EEZ40775">
        <property type="protein sequence ID" value="EEZ40775"/>
        <property type="gene ID" value="VDA_001807"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4172">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1303270at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="8"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="46"/>
            <end position="53"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="274" mass="30838" checksum="201580DF36F2834A" modified="2010-01-19" version="1">MSALLEVVKLKKDYQYRSGLFRRRTIEAVKPVSFSLEAGETIALLGENGSGKSTLAKMLAGVVEPTSGLIKVNGEPLVSGDYETRCKLIRMIFQDPNTALNPRIQIGRILEGPLKRNTNMTPQERENRVLQTLRRVGLLPEHAYFYPQMLATGQKQRVSLARALILQPCIIVADEALNGLDMSMRSQMINLLLELQEEMGLSYVYVSQHMGVIKHFSDKIMVMQDGEVVEKGRTKEVFEDPKHPLTQKLIESHFSAPTQDRTTRISKATPKIKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWX6</accession>
    <name>D0YWX6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Peptide transport system permease protein SapC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_001809</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298744.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001809"/>
    <dbReference type="EnsemblBacteria" id="EEZ40777">
        <property type="protein sequence ID" value="EEZ40777"/>
        <property type="gene ID" value="VDA_001809"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4171">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1734230at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025966">
        <property type="entry name" value="OppC_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12911">
        <property type="entry name" value="OppC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="28"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="98"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="222"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="260"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="98"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="295" mass="32207" checksum="8B62D676AF88F4F2" modified="2010-01-19" version="1">MPSNNVYLEEVIPTQWERTWQHFRANSLAMFGLWCLLFLLLVTCTAHWLAPYSPIQQVGELLMPPSWDNSGHVEFFFGTDDLGRDILSRLLIGTQLTFGYALLIALAASVIGFAIGVLAGMTKGLKSSILNHILDTVLSIPSLLLAIIMVAYMGPGEAHVLLAVWLALIPRFIRAIYTAVHTEMEKDYIIAARLDGANNVYLLYNSVLPNILTVITTEMTRAISIAILDIAALGFLGLGAQPPMPEWGAMLGDSVDLIYLAPWTVTLPGLSIMFSVLVINLVGDGLRQALNAGID</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWY1</accession>
    <name>D0YWY1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phage shock protein B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001814</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298755.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001814"/>
    <dbReference type="EnsemblBacteria" id="EEZ40782">
        <property type="protein sequence ID" value="EEZ40782"/>
        <property type="gene ID" value="VDA_001814"/>
    </dbReference>
    <dbReference type="GeneID" id="57342071"/>
    <dbReference type="eggNOG" id="ENOG5032YI2">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2100036at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009271">
        <property type="term" value="P:phage shock"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009554">
        <property type="entry name" value="Phageshock_PspB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06667">
        <property type="entry name" value="PspB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02976">
        <property type="entry name" value="phageshock_pspB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="37"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="75" mass="8752" checksum="F249C358F42A45B8" modified="2010-01-19" version="1">MSMGFLAVPLVVFCIFVAPLWLILHYRSKRRLGEGLSGEEQEKLQKLVARAEQMQERIVTLERILDAEAPQWRQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWZ3</accession>
    <name>D0YWZ3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">Lysozyme</fullName>
            <ecNumber evidence="2 6">3.2.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_002046</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>Hydrolysis of (1-&gt;4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.17"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the glycosyl hydrolase 24 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.17" evidence="2 6"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299266.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41014">
        <property type="protein sequence ID" value="EEZ41014"/>
        <property type="gene ID" value="VDA_002046"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3772">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1703032at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003796">
        <property type="term" value="F:lysozyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016998">
        <property type="term" value="P:cell wall macromolecule catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019835">
        <property type="term" value="P:cytolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042742">
        <property type="term" value="P:defense response to bacterium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009253">
        <property type="term" value="P:peptidoglycan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.530.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_04110">
        <property type="entry name" value="ENDOLYSIN_T4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034690">
        <property type="entry name" value="Endolysin_T4_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002196">
        <property type="entry name" value="Glyco_hydro_24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023347">
        <property type="entry name" value="Lysozyme_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00959">
        <property type="entry name" value="Phage_lysozyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0929">Antimicrobial</keyword>
    <keyword evidence="4 6" id="KW-0081">Bacteriolytic enzyme</keyword>
    <keyword evidence="6 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 6 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="180" mass="19561" checksum="BD48B00AD0331FBD" modified="2010-01-19" version="1">MSKWKTTSGAITCVVASVLAVVAGTDHHLKTSPDGLAFISNLEGCSSVAYQCSADRWTAGLGHTKNVKEGDSANTEQIADWFIEDIAAAEKVVNREVTLPAGPKYDMAVSFVFNLGAGNFRSSTYLKKLKAGQLDAACYEFPRWVYVNGKDCRIDGNHCSGIVTRRLAEKEVCLYGYSQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX75</accession>
    <name>D0YX75_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Serine transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_001836</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298788.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001836"/>
    <dbReference type="EnsemblBacteria" id="EEZ40804">
        <property type="protein sequence ID" value="EEZ40804"/>
        <property type="gene ID" value="VDA_001836"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="369689at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003333">
        <property type="term" value="P:amino acid transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018227">
        <property type="entry name" value="Amino_acid_transport_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03222">
        <property type="entry name" value="Trp_Tyr_perm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="22"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="48"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="139"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="203"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="242"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="293"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="339"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="365"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="395"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ40804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="417" mass="45022" checksum="C95CEAC22242641B" modified="2010-01-19" version="1">MQTTSTTAATGTAKARWTYKDFTWALSLFGTAVGAGVLFLPIKAGAGGFWPLVALALLALPMTWFAHKGLARFVLSAKNPEADITDTVEEHFGKTGANIITFAYFFAIYPIVLIYGVGITNTVDSFMVHQLGMDSMPRWLLSGLLISAMTAGVVFGKELMLKATSAMVYPLVAVLLILSIYLIPDWNTSMMSVAPDWSAMPAVVWLAIPIIVFSFNHSPIISQFSKEQRRVYGEDAVKKTDMITGGAAMMLMGFVMFFVFSVVLSMTPEQLATAKAENISVLSYLANVHESPYISLLGPLVAFAAITSSYFGHFLGAHEGLVGLVKSRSDMSISKIEKISLVFIVVTTWIVAIINPSILGMIETMGAPMIAAILFLMPVFAMYKVPAMAKYKTSSAARIFTALCGIASITSVIYGAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX88</accession>
    <name>D0YX88_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2-amino-3-ketobutyrate coenzyme A ligase</fullName>
            <shortName evidence="1">AKB ligase</shortName>
            <ecNumber evidence="1">2.3.1.29</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Glycine acetyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">kbl</name>
        <name evidence="3" type="ORF">VDA_001947</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>acetyl-CoA + glycine = (2S)-2-amino-3-oxobutanoate + CoA</text>
            <dbReference type="Rhea" id="RHEA:20736"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:78948"/>
            <dbReference type="EC" id="2.3.1.29"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
        <text evidence="1">Binds 1 pyridoxal phosphate per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid degradation; L-threonine degradation via oxydo-reductase pathway; glycine from L-threonine: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.29" evidence="1"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298992.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001947"/>
    <dbReference type="EnsemblBacteria" id="EEZ40915">
        <property type="protein sequence ID" value="EEZ40915"/>
        <property type="gene ID" value="VDA_001947"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0156">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="479874at2"/>
    <dbReference type="UniPathway" id="UPA00046">
        <property type="reaction ID" value="UER00506"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008890">
        <property type="term" value="F:glycine C-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019518">
        <property type="term" value="P:L-threonine catabolic process to glycine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00985">
        <property type="entry name" value="2am3keto_CoA_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011282">
        <property type="entry name" value="2am3keto_CoA_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001917">
        <property type="entry name" value="Aminotrans_II_pyridoxalP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01822">
        <property type="entry name" value="2am3keto_CoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00599">
        <property type="entry name" value="AA_TRANSFER_CLASS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="2">
        <location>
            <begin position="43"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="1">
        <location>
            <begin position="111"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="1">
        <location>
            <begin position="210"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="1">
        <location>
            <begin position="241"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding; shared with dimeric partner" evidence="1">
        <location>
            <begin position="274"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="368"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="1">
        <location>
            <position position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="397" mass="43074" checksum="7CD9DE49B8840FFB" modified="2010-01-19" version="1">MSSAFYQQIQQQIADVKTEGLYKSERIITSAQKAAVSINTGEEVLNFCANNYLGLANHPELINAAKQGMDEHGFGMASVRFICGTQDAHKELEQKLSAFLGMEDTILYSSCFDANAGLFETILGAEDAIISDALNHASIIDGVRLCKAMRFRYSNNNMQELEEQLIAADNAGARHKLIVTDGVFSMDGVVANLPAICDLADKYNALVMVDDSHAVGFMGENGRGTHEYHSVMDRIDIITGTLGKAMGGASGGYTAGKKEVIDWLRQRSRPYLFSNSVAPAIVAASNRVIDLLAESGDLRSHLWDNAEHFRRRMTEAGFTMAGADHAIIPIMLGDAKVAAEFAERALAKGIYVVGFSFPVVPKGQARIRTQMSAAHSREQLDQAIDAFIAVGKDMGII</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXA4</accession>
    <name>D0YXA4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">tRNA-specific 2-thiouridylase MnmA</fullName>
            <ecNumber evidence="7">2.8.1.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">mnmA</name>
        <name evidence="8" type="ORF">VDA_001644</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>AH2 + ATP + S-sulfanyl-L-cysteinyl-[protein] + uridine(34) in tRNA = 2-thiouridine(34) in tRNA + A + AMP + diphosphate + H(+) + L-cysteinyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:47032"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11726"/>
            <dbReference type="Rhea" id="RHEA-COMP:11727"/>
            <dbReference type="Rhea" id="RHEA-COMP:11728"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61963"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:87170"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.8.1.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the MnmA/TRMU family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.13" evidence="7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001644"/>
    <dbReference type="EnsemblBacteria" id="EEZ40617">
        <property type="protein sequence ID" value="EEZ40617"/>
        <property type="gene ID" value="VDA_001644"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0482">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016783">
        <property type="term" value="F:sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01998">
        <property type="entry name" value="tRNA_Me_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00144">
        <property type="entry name" value="tRNA_thiouridyl_MnmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023382">
        <property type="entry name" value="Adenine_a_hdrlase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004506">
        <property type="entry name" value="tRNA-specific_2-thiouridylase"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00420">
        <property type="entry name" value="trmU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="2 7" id="KW-0820">tRNA-binding</keyword>
    <feature type="region of interest" description="Interaction with target base in tRNA" evidence="7">
        <location>
            <begin position="61"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with tRNA" evidence="7">
        <location>
            <begin position="115"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with tRNA" evidence="7">
        <location>
            <begin position="280"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="7">
        <location>
            <position position="66"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine persulfide intermediate" evidence="7">
        <location>
            <position position="165"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Interaction with tRNA" evidence="7">
        <location>
            <position position="92"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with tRNA" evidence="7">
        <location>
            <position position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ40617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="333" mass="37636" checksum="0C0308F29903799E" modified="2010-01-19" version="1">MKNWEEDDNEEYCSAAADLADAQAVCDKLGIPLHTINFAAEYWDNVFEYFLAEYKAGRTPNPDILCNKEIKFKAFLEFADEVLEADYIAMGHYTRRTFPQAGEEPQMLRGLDNNKDQSYFLYTLSHEQIARSLFPVGELEKPEVRRIAEEQGLVTAKKKDSTGICFIGERKFTEFLGKYLPAQPGNIVTADEGTVIGEHQGLMYHTLGQRKGLHIGGQKGGNGHEDPWYVVDKDVKRNELVVAQGHDHPRLKSNGLIASQLHWVDREPIRQPVTCTVKTRYRQQDIPCTIIPIDDENIKVIFDEPQIAVTPGQSAVFYNGEVCMGGGIIEERI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXI8</accession>
    <name>D0YXI8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="15">PTS system maltose and glucose-specific IIBC component</fullName>
            <ecNumber evidence="15">2.7.1.69</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">VDA_001694</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.7.1.69" evidence="15"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298528.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001694"/>
    <dbReference type="EnsemblBacteria" id="EEZ40665">
        <property type="protein sequence ID" value="EEZ40665"/>
        <property type="gene ID" value="VDA_001694"/>
    </dbReference>
    <dbReference type="GeneID" id="57342225"/>
    <dbReference type="eggNOG" id="COG1263">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1264">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2035550at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103111">
        <property type="term" value="F:D-glucosamine PTS permease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008982">
        <property type="term" value="F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00212">
        <property type="entry name" value="PTS_IIB_glc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036878">
        <property type="entry name" value="Glu_permease_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018113">
        <property type="entry name" value="PTrfase_EIIB_Cys"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003352">
        <property type="entry name" value="PTS_EIIC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013013">
        <property type="entry name" value="PTS_EIIC_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001996">
        <property type="entry name" value="PTS_IIB_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00367">
        <property type="entry name" value="PTS_EIIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02378">
        <property type="entry name" value="PTS_EIIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55604">
        <property type="entry name" value="SSF55604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00826">
        <property type="entry name" value="EIIB_glc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51098">
        <property type="entry name" value="PTS_EIIB_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01035">
        <property type="entry name" value="PTS_EIIB_TYPE_1_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51103">
        <property type="entry name" value="PTS_EIIC_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0598">Phosphotransferase system</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="5 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="58"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="89"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="132"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="199"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="223"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="296"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="321"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="344"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="376"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="403"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="domain" description="PTS EIIC type-1" evidence="14">
        <location>
            <begin position="1"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="domain" description="PTS EIIB type-1" evidence="13">
        <location>
            <begin position="461"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphocysteine intermediate; for EIIB activity" evidence="11">
        <location>
            <position position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEZ40665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="541" mass="57821" checksum="5251DC2FA26FC8B4" modified="2010-01-19" version="1">MKAFFSKLSQAVMLPIALLPAAGIMLGIGGSFTNQSMIEAYNIGILQDGTVLNSFLQIMTAAGGIVFANLPLMFALAIAIGFARAEKGAAALAATIAYLVMNVAIAKTLSVAGMVDTADNTVVLMGSHYTGVLADVLGIHNTLSMGVFGGLIAGGITVVLHNKYHDIKLPEFLGFFGGARFVPIVSAFSALFYGIALVFIWPFIGAGFGTIGAMLGEMTASGHGYIASFIFGIIERALIPVGLHHVFYLPLWQTEIGGTAEIAGHVYKGTQNIFFGSLANGDYSHFSSTNFMSGKFPFMMFGLPAAAYAMYTVADKENKKEVGGLLFSVALTAFLTGITEPIEFTFLFLSAPLYYFIHVPLAGLSFMIMDLLHVKVGMTFSGGFIDFALFGMLPGLTGTNNHWYYIPLLGVIYGPLYFFLFRWFILKYDIKTPGRKGSAVAVVRKKDYQASKAAGAAGSDDDQIDLMIEALGGKDNIEDVDACITRLRITVKNGDLVKDNQYWTQELGAKGLVKVGGTGIQAIYGAQAAGYKAQINSKLGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXS3</accession>
    <name>D0YXS3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002086</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299389.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002086"/>
    <dbReference type="EnsemblBacteria" id="EEZ41054">
        <property type="protein sequence ID" value="EEZ41054"/>
        <property type="gene ID" value="VDA_002086"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5563">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1353997at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022562">
        <property type="entry name" value="DUF3466"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020008">
        <property type="entry name" value="GlyGly_CTERM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11949">
        <property type="entry name" value="DUF3466"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03501">
        <property type="entry name" value="GlyGly_CTERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018668" evidence="1">
        <location>
            <begin position="24"/>
            <end position="673"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="673" mass="73393" checksum="D2881F91E2195C01" modified="2010-01-19" version="1">MQHKMLKLSTLAVLIAGVTQAQAAVYKVVEVATPDNQSNALATDYYPNHDRSGSTDQFKNNAVEFYAQSIAQDGTVVGNSRFGNDGINYSDVVAFHMDNYQRINDYNELYRYCRENLGFNTCDVWAEMRYYGKNYNRNEADDGTGFGGLRTEQAAWWNGYFANALPFVYGQTNYLSTFAGDASRYADQDKLGSIVDGGDHVTANAMVLGALDSNTVYGVTSSAYFNNDSRFARTFAKRGFVNDLSASSSTELNPIGDNALVTKMGQSVANHAVKLPSGDLLVVGSASYTPSNYDDGDKLPDYDDIDGGNVDASKGRANYNVDTFRKCETEPNSIYGNWVCQFTSYANKAVFWVVKAGDTSVKGQELASTSLNAWDPDDKDRSFQGNAKSVALVNGKPIAVGYSTDDVRNDYYANRAAVFTPKSDMDINNPKADDWSIKFIPGTEITDGDDRKLSYSMATAINDNGKVAGVAKNFNSEDRSYAERMFIYDNASNQTKFLTSSVNSLFFNGSNGYLSSINDANKAVGWVDIEKVNQVDGRERRQRAFLYNDGQADGALTANGAWLVDDLTNGGTESAHNNQYRIAQATGINDKGEISATALKCTSDGVTPKQYSDTSPLAQCDGYEVLTAVKLEPVAGGTIEPRKDVEEPVKRSGGSLGVLALTVLGFIGFRRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXU2</accession>
    <name>D0YXU2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidase S1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002105</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299446.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002105"/>
    <dbReference type="EnsemblBacteria" id="EEZ41073">
        <property type="protein sequence ID" value="EEZ41073"/>
        <property type="gene ID" value="VDA_002105"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502ZRSD">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="596096at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018671" description="Peptidase S1 domain-containing protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="2">
        <location>
            <begin position="71"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="573" mass="63282" checksum="458095ABC0D106CA" modified="2010-01-19" version="1">MKLRSIPLALIATGLFYSSSVNAIALTDSKYTDIAGSLDPALKQTVTSHLNELASTESYNSVGLVIGNGYCSGTWLGSDNSHSYILTAAHCLAGSTSNEYTGQTVSFKLQDGTLIASGIATNYFHDYLNCGSDIAVAKIPKVVDPLDSTGNVIPQPFINTTLDGNELHSGVNFTGFGVFGTRSLGQLDWIGKRHGKGNFIGLYSNCLINRAVENTDSWAFASPGDSGSASWQERKGHPVAVGIASWWFGWYWGYSGHAAIGPHGDWLKSVVPVLKTVDDIPDEPVETQFVLTEKEPLLTDNIEKDIRGSAYYVKGANIVDGPNRYIWRYPRATTSFSVNLTHQESNVSYKVWLQGQRKTYCGWGKVNNSAWCYPRPDLGQLKLKFDQKDNPSLPIGTYTGDFSFIALSLYNRQFQQEIPIQANIVIDQELPADGEITESSPYLGERLDKETYGTVYYLAKEMIGVPRPIWSGRRGIYKRIHIELQNTETGAIERVALRSERNLGCGWSTMNNAAYCWRKGPNYGELRVSYVADDNLDLPIGAYSGVLNVTAKGLHNRSFQRQLLLNINIVKTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXV5</accession>
    <name>D0YXV5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Putrescine-binding periplasmic protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_002118</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for the activity of the bacterial periplasmic transport system of putrescine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial solute-binding protein PotD/PotF family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299483.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002118"/>
    <dbReference type="EnsemblBacteria" id="EEZ41086">
        <property type="protein sequence ID" value="EEZ41086"/>
        <property type="gene ID" value="VDA_002118"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0687">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1264541at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019808">
        <property type="term" value="F:polyamine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015846">
        <property type="term" value="P:polyamine transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001188">
        <property type="entry name" value="Sperm_putr-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019574">
        <property type="entry name" value="Periplasmic_polyamine_BP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00909">
        <property type="entry name" value="SPERMDNBNDNG"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0574">Periplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019875" description="Putrescine-binding periplasmic protein" evidence="3">
        <location>
            <begin position="25"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Spermidine-binding" evidence="2">
        <location>
            <begin position="167"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>spermidine</name>
            <dbReference type="ChEBI" id="CHEBI:57834"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>spermidine</name>
            <dbReference type="ChEBI" id="CHEBI:57834"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="326"/>
        </location>
        <ligand>
            <name>spermidine</name>
            <dbReference type="ChEBI" id="CHEBI:57834"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR019574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR019574-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="347" mass="39313" checksum="FB126B3E4E0B2EBB" modified="2010-01-19" version="1">MKKWSSLMTGAVCAMAMFSNVASAADNELYFYNWSEYIPQDVIEQFTKETGIKVIYSTYESNETMYAKLKTNGEGYDLVVPSTYYVSKMRDEGMLQKIDHSKLSHFKDLDPNFLDKPFDPNNDYSIPYIWGATGIGVNTDVIDKSKIHSWADLWDPKWEGQLMMMDDAREFFHIGLRKLGYSGNTKDPAQIKAAYEELKKLMPNVLVFNSDYPANPYMAGETSLGMLWNGSAYQAQQEGAPIDIVWPKEGAIFWMDSLSIPAQAKHIDAAYKMIDFLLRPENAAKIAQQIGYPTPVATAKKFLPKSFVNNPMIYPPQSVLDAGEWQNSVGSANELYEEYFQKLKAGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXX6</accession>
    <name>D0YXX6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Murein-DD-endopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_002139</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the peptidase S11 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002139"/>
    <dbReference type="MEROPS" id="S11.002"/>
    <dbReference type="EnsemblBacteria" id="EEZ41107">
        <property type="protein sequence ID" value="EEZ41107"/>
        <property type="gene ID" value="VDA_002139"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1686">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009002">
        <property type="term" value="F:serine-type D-Ala-D-Ala carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018044">
        <property type="entry name" value="Peptidase_S11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001967">
        <property type="entry name" value="Peptidase_S11_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00768">
        <property type="entry name" value="Peptidase_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00725">
        <property type="entry name" value="DADACBPTASE1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0133">Cell shape</keyword>
    <keyword evidence="5" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="4" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Peptidase_S11" evidence="9">
        <location>
            <begin position="2"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="6">
        <location>
            <position position="5"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="8"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="62"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR618044-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR618044-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ41107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="242" mass="26515" checksum="52C9E88ACEB66EA4" modified="2010-01-19" version="1">MPIASITKLMTAMVTLDAKLPLNEKITFNKADKERMYNNYTRVRLGSTLSRGETIHIALMSSENLAAAALAGHYPGGSKAFVKAMNAKAKALGMTHTRFVDSSGLDPRNVSTASDVSKLVRAAYKYPQIRKYSTTPVHTAYFGKPNYKLGYTNTNALARGKKWTVNLTKTGHLKVAGHCLAMVTTIQGRKYLMVMLDTQGKLTPVGDAGRIKKWLETGHSGDISASAKAYQTQKYKQLTHKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY25</accession>
    <name>D0YY25_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Elongation factor P-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_002188</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the elongation factor P family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299614.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002188"/>
    <dbReference type="EnsemblBacteria" id="EEZ41156">
        <property type="protein sequence ID" value="EEZ41156"/>
        <property type="gene ID" value="VDA_002188"/>
    </dbReference>
    <dbReference type="GeneID" id="57341672"/>
    <dbReference type="eggNOG" id="COG0231">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1260763at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04470">
        <property type="entry name" value="S1_EF-P_repeat_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05794">
        <property type="entry name" value="S1_EF-P_repeat_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00646">
        <property type="entry name" value="EFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015365">
        <property type="entry name" value="Elong-fact-P_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020599">
        <property type="entry name" value="Transl_elong_fac_P/YeiP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013185">
        <property type="entry name" value="Transl_elong_KOW-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011897">
        <property type="entry name" value="Transl_elong_p-like_YeiP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001059">
        <property type="entry name" value="Transl_elong_P/YeiP_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013852">
        <property type="entry name" value="Transl_elong_P/YeiP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30053">
        <property type="entry name" value="PTHR30053"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01132">
        <property type="entry name" value="EFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08207">
        <property type="entry name" value="EFP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09285">
        <property type="entry name" value="Elong-fact-P_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005901">
        <property type="entry name" value="EF-P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01185">
        <property type="entry name" value="EFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00841">
        <property type="entry name" value="Elong-fact-P_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02178">
        <property type="entry name" value="yeiP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01275">
        <property type="entry name" value="EFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EFP" evidence="4">
        <location>
            <begin position="69"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="Elong-fact-P_C" evidence="3">
        <location>
            <begin position="132"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="189" mass="21107" checksum="59231767F91E9F93" modified="2010-01-19" version="1">MPRANEIKKGAAVELNGKLLLVKDIDVQSPSARGASTLYRMRFTDVATGLKVEERFKGDDILETVDLSRHQSSFSYVDGDEYIFMDNEDFTQYTFNKEDIEDELLYITEDIQGLLVLVANEKPIGLELPASVEMVIEETDPSIKGASASARTKPARFATGLTVQVPEYIATGDKVRINTSERKFMCRAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY86</accession>
    <name>D0YY86_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative carrier/transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_002249</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the BI1 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002249"/>
    <dbReference type="EnsemblBacteria" id="EEZ41217">
        <property type="protein sequence ID" value="EEZ41217"/>
        <property type="gene ID" value="VDA_002249"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0670">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006214">
        <property type="entry name" value="Bax_inhibitor_1-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23291">
        <property type="entry name" value="PTHR23291"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01027">
        <property type="entry name" value="Bax1-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="104"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="162"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="191" mass="20160" checksum="9746F4D3DBA39BD1" modified="2010-01-19" version="1">MTLLWSAVVAGVAMAMNLPPVHWIVTLVGFYGLLFLTERNRDSSVGLVCVFALTGFMGYTLGPILNMYVGAGLGSAIVPALGGTALTFLACSAYALTTKRDLSFLNGVMLAGFIAIIVAVIANIFLQMSVLSLVISGMFVLFSSAAILLTTQSIVRGGETNYISATVTLYVSIYNLFLSLLQILGVVNSND</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYH5</accession>
    <name>D0YYH5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9 11">FAD:protein FMN transferase</fullName>
            <ecNumber evidence="3 9 11">2.7.1.180</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Flavin transferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">VDA_002338</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9 11">
            <text>FAD + L-threonyl-[protein] = AMP + FMN-L-threonyl-[protein] + H(+)</text>
            <dbReference type="Rhea" id="RHEA:36847"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11061"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:74257"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.1.180"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="10">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="10">Magnesium. Can also use manganese.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cell inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 11">Belongs to the ApbE family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.180" evidence="3 9 11"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299912.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002338"/>
    <dbReference type="EnsemblBacteria" id="EEZ41306">
        <property type="protein sequence ID" value="EEZ41306"/>
        <property type="gene ID" value="VDA_002338"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2021063at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017013">
        <property type="term" value="P:protein flavinylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024932">
        <property type="entry name" value="ApbE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003374">
        <property type="entry name" value="ApbE-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30040">
        <property type="entry name" value="PTHR30040"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02424">
        <property type="entry name" value="ApbE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006268">
        <property type="entry name" value="ApbE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143631">
        <property type="entry name" value="SSF143631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 11" id="KW-0274">FAD</keyword>
    <keyword evidence="5 9 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="11 12" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="8 9 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9 11" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="10">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="301"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="305"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR006268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR006268-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ41306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="353" mass="39158" checksum="DA5C6DF40BFE7FC7" modified="2010-01-19" version="1">MFVNTKKIQPSKMGCAALAVSISLLLSGCNEPPKLEKITGFAEGTTYHVTYWSKDDVPVTKVQAQFDKRLAEIDKEFSTYRNDSYISEFNHSASTQWQPASKEFIDLVALAKTINKDSGGCYDPTIQPLYKLWGFQGDKLHVPTHEEITTIQGDMGINNIEIDPTHLKIRKAIPQVQIDLSSMGEGFAISQLSKILEADGINNYLVEFGGDMKIKGHKPNGVQWRVAIEQPISLKEGVKPYQVVTIFDQSGVSLNTSGTYHHNFEQGKKEYSHILDPRTGSPITHNLVSASVFGNDPIKGDAWATTMLCLGPKQGMEAANKLNLPVFFIQDEEGKFISSSSDEFKETKAFSMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYJ0</accession>
    <name>D0YYJ0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_002353</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299937.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41321">
        <property type="protein sequence ID" value="EEZ41321"/>
        <property type="gene ID" value="VDA_002353"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1914">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="416257at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046873">
        <property type="term" value="F:metal ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001046">
        <property type="entry name" value="NRAMP_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11706">
        <property type="entry name" value="PTHR11706"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01566">
        <property type="entry name" value="Nramp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="94"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="132"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="157"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="196"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="235"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="283"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="321"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="344"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="379"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="410" mass="43218" checksum="AA93379ED7225698" modified="2010-01-19" version="1">MTTSTTTAIPSSESQTASWQSKAIMSVAFLMATTSVGPGFLTQTAVFTNLYKIDMAFPVLISAFITFGIVMNIWRIVGVSGLRIQDIANKVAPGLGYVVGILLALGAVAFNFGNVSGSALGINVLTGVDTTWGALFTGGLGCLLFVLHNASKRMDQMARYLGLFMIILIAYVAMTSLPPMGQTLIAAVAPSDMSNLLLPTLTIVGGAVGGYYTGAQRLVDIGLQGQNNVDNIKKAAWAGISIAVVIRVLLFLAIFGVIATGAVLDKANPAADAFRHGAGDVGYFIFGLVLFVASITSVVGNSYMAISLIKTLFPVVARNEKLWCVGFIIITSLGTVMMNMPILLLMLAGLVNSIILPIVLGSVLAATRRKDIVGDYKHPILLTAIGTLIVIVMAFASYTNILNFMTKFLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYP2</accession>
    <name>D0YYP2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alcohol dehydrogenase</fullName>
            <ecNumber evidence="3">1.1.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002405</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.1" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300031.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002405"/>
    <dbReference type="EnsemblBacteria" id="EEZ41373">
        <property type="protein sequence ID" value="EEZ41373"/>
        <property type="gene ID" value="VDA_002405"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1454">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1456634at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004022">
        <property type="term" value="F:alcohol dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001670">
        <property type="entry name" value="ADH_Fe/GldA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018211">
        <property type="entry name" value="ADH_Fe_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039697">
        <property type="entry name" value="Alcohol_dehydrogenase_Fe"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11496">
        <property type="entry name" value="PTHR11496"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00465">
        <property type="entry name" value="Fe-ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00913">
        <property type="entry name" value="ADH_IRON_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00060">
        <property type="entry name" value="ADH_IRON_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe-ADH" evidence="2">
        <location>
            <begin position="8"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="382" mass="40246" checksum="60314DE66B29F62E" modified="2010-01-19" version="1">MASAFFIPTVNYMGADCLTDAADAIKAHGFKKALIVTDKILSQIGMVKQVADLLAERGVESVVFDGTQPNPTIGNVEAGLALLKDNQCDFVISLGGGSPHDCAKGIALVAANGGQVADYEGVDRSEKPQMPLIAINTTAGTASEMTRFCIITDEARHIKMAIVDKHTTPLMSVNDPKLMLAKPASLTAATGMDALTHAIEAYVSIAATPVTDAVAIKAIELIQENLRTAVKDGQNLHAREQMAYAQFMAGMAFNNASLGYVHAMAHQLGGFYDLPHGVCNAILLPHVQRYNAQVSADRLRDVAKAMGVNVEGMTAEQGAEAAIEAIVTLAKDVGIPAGIKELGAKAEDVAILADNALKDACGFTNPKQATHEEICEIFMAAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYU7</accession>
    <name>D0YYU7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipoprotein putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002460</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300136.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002460"/>
    <dbReference type="EnsemblBacteria" id="EEZ41428">
        <property type="protein sequence ID" value="EEZ41428"/>
        <property type="gene ID" value="VDA_002460"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5184">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="308036at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="SSF50985"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="523"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="523"/>
            <end position="538"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="884" mass="98272" checksum="4B48420213BEF27F" modified="2010-01-19" version="1">MRKVWLVSALVLGGCGGGGGDDAAATPVKNSADNTVKTSSTPILNPSRNKVASATEEKVNSNRETVVLNNREHQPVVTISPPLSIDKKLEVTEIKPEDFVTSSSSQNVIKESAVKDIQQDHLSLDKPAEIADLNKGISLDDQTISIAVNPEDSNIIEESVNKDQVKPLDVSSNRVGSYQVYQLPENINDVLKSHPASSEIQVGRLLNISRLNNKLNDYYDVYGARDKLSFKVSFLSAQETEYTKVACRWISEGETSAQDHELSTKCEYQLSGNEYLKPLLIEVRYYIKDQLHLAKFRYQKRFLIDRKSNTLGSVNLYNDSDISENITLAESGLAQMNRSLSEEFKHNIRKVEANYSGFAAINMQGNLFTWGTKTFIGEEDYLQTVNQEKIVDVVPSLRSFAVLNEYGQVHVVGSLGNFTDTLLQDQFKFTQMMGNKHAFALKTENGQVCLVTDKMTKADFSGTCKYLKQDAPIAKFVGLGQDFNGFAILTTRGELVEWGSASHEYKQYLRDIAAQKVKESQEQAEKEALAKEKGELSDTDLSPSTSQLIQATDAKTHFNWDLYFDKLRNIDNNEPSLLFNDLVATDGAFAALTKNKKVIVWGISSYGGSPVYDYAGFKVKLVEDTTTCKESNKTFYTQDGCPNGLKRVPVPGYYQQMRVNEVNQKLLEPLENIKKVVANHGAFAALTESGQVLTWGSVFYGGNTYSHELKGLHSELENAKDIMASDDGFTALFANGKTLSWKGIWNLSAKKGDQVSFEKFYDYDSVSTEDKYGWFRGFGLKDGNNVGHFITNGEAFMAISGISDEPKAWISSWGNKEFGGGLLDSTRDLIVIPERIIATYPDHYGFTFVTAYGDVYSWSGNDRGTYIGSFDIKKAAPVSKTQIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYV2</accession>
    <name>D0YYV2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Signal transduction c-di-GMP phosphodiesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002465</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300145.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002465"/>
    <dbReference type="EnsemblBacteria" id="EEZ41433">
        <property type="protein sequence ID" value="EEZ41433"/>
        <property type="gene ID" value="VDA_002465"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3434">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="753726at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014408">
        <property type="entry name" value="dGMP_Pdiesterase_EAL/HD-GYP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013976">
        <property type="entry name" value="HDOD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08668">
        <property type="entry name" value="HDOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003180">
        <property type="entry name" value="DiGMPpdiest_YuxH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51833">
        <property type="entry name" value="HDOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EAL" evidence="1">
        <location>
            <begin position="1"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="HDOD" evidence="2">
        <location>
            <begin position="200"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="411" mass="47418" checksum="5B46675922D915CB" modified="2010-01-19" version="1">MFSYIARQPILNTERKTVGYELLFRDGPQNSYPNVDEEQATNQLLNDNFFSLAGPVHITSGKRAFVNFPYDSLIKGTPLLFAKQSFVIEILESCQPTNELFYAVINLYKKGYTLALDDFMPSEAWNRFLPYIHIIKFDIRILPIEKAARFIEHYKKRTNIRFLAEKVETYEEFIAAKDAGFELFQGYFFSKPEMLQRKSLKPSALTAIRLLKEICVDEVNYDKVEEIIATDVSLSYKLLRHVNMMTSNRAKPIASFKQALVYLGEEKLRRFITFVVTSHALQAKPQALHNLSLQRAYFCESLSKLVNKNIDGNQAFLTGLFSLLDSLLDQPLTDLVNNLPLTQDVKDALIERTGQLGDILQLAEAFDNAQWDTVNYYNRFLGLKEESIAELYLESVQWATTFEKNWQQVND</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ12</accession>
    <name>D0YZ12_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transmembrane regulatory protein ToxS</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002525</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002525"/>
    <dbReference type="EnsemblBacteria" id="EEZ41493">
        <property type="protein sequence ID" value="EEZ41493"/>
        <property type="gene ID" value="VDA_002525"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031MTT">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035288">
        <property type="entry name" value="ToxS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17323">
        <property type="entry name" value="ToxS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="22"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="187" mass="21873" checksum="E75320734D75FCC5" modified="2010-01-19" version="1">MSLSSTNNNSISLVMINFLKRYWALLLLLISIVGSAWFYLSSDYKLAQMLMSREWQSSTYSRIEPTQLDDLRMLRRVEQNSHMVYLPNHTYSRITVMKLFSQDEEPISLHISETGKWNISGQYLITRPLEFKEITSGSNPDFNNQNLKVVKKIFQMDAEQSRKMEIINDKTILFTSLTYGSNIFYSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ38</accession>
    <name>D0YZ38_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Multidrug resistance efflux pump</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_002551</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300306.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002551"/>
    <dbReference type="EnsemblBacteria" id="EEZ41519">
        <property type="protein sequence ID" value="EEZ41519"/>
        <property type="gene ID" value="VDA_002551"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1566">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1680841at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043602">
        <property type="entry name" value="CusB_dom_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00529">
        <property type="entry name" value="CusB_dom_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CusB_dom_1" evidence="3">
        <location>
            <begin position="9"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="4">
        <location>
            <begin position="37"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="93"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="335" mass="36926" checksum="79CECCBACF12EF78" modified="2010-01-19" version="1">MKKKVIVFIGIILATVAGYRYIESQNEESTDNAYVHADVTAISPEVGGQVMAIHVKDNQWVKQGTPLFSIDNADYEANYQISQAAVEVAQAALKNNQTRIDMQKVKIEQAKQNIASADANANHQNAELKRFARLLKPKMISENHYEAQRSTTIDANAKLKSAQLLLTSEQKLLETLHTEKQQLIAQVQQVQAKLKLNAISLQRTVIKAPFDGYIASRQVQVGKYVQPGMGVIVMVPRKVWVEANFKETQLKEISVGQIVDVVLDGYPDTVLTGKVDSITPATGAQFSLLPAQNATGNFVKVVQRVPVRIDITIPKALEHKVYPGLSAEVTVVTQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ53</accession>
    <name>D0YZ53_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNA polymerase sigma factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_002566</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300345.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002566"/>
    <dbReference type="EnsemblBacteria" id="EEZ41534">
        <property type="protein sequence ID" value="EEZ41534"/>
        <property type="gene ID" value="VDA_002566"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1914729at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000838">
        <property type="entry name" value="RNA_pol_sigma70_ECF_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01063">
        <property type="entry name" value="SIGMA70_ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="4">
        <location>
            <begin position="28"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="5">
        <location>
            <begin position="119"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="189" mass="22344" checksum="673030A1D541E609" modified="2010-01-19" version="1">MIKKFFGKKKPDASVSLDMNRQRRYEALVRAWHRDLYRYAYWLCKDPHIAEDLVQETCLRAWRSLDSLQDDNAAKSWLITILRRENARRFERKQFETVDIDDHHIADEQSSSDGDYQQQQLHSMIMNLAPEYREPLVLQVMAGFSGEEIAEILGLNKNTVMTRLFRARNQLKEQLDDNNQVRGQKNGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZH4</accession>
    <name>D0YZH4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">tRNA-specific adenosine-34 deaminase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002687</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002687"/>
    <dbReference type="EnsemblBacteria" id="EEZ41655">
        <property type="protein sequence ID" value="EEZ41655"/>
        <property type="gene ID" value="VDA_002687"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0590">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="71" mass="7935" checksum="C60501B52F054C21" modified="2010-01-19" version="1">MGKVVYGAPDLKTGAAGSTMNLLSYAGVNHHVQFDAGLLEDECRAQLQAFFKRRRAEKKALKQAEKEKQQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZJ0</accession>
    <name>D0YZJ0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hypothetical fimbrial biogenesis and twitching motility protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002703</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300745.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002703"/>
    <dbReference type="EnsemblBacteria" id="EEZ41671">
        <property type="protein sequence ID" value="EEZ41671"/>
        <property type="gene ID" value="VDA_002703"/>
    </dbReference>
    <dbReference type="GeneID" id="57341026"/>
    <dbReference type="eggNOG" id="COG3063">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1382732at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013360">
        <property type="entry name" value="Pilus_4_PilW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02521">
        <property type="entry name" value="type_IV_pilW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="36"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="140"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="251" mass="28752" checksum="5A6D8633AFC7BC86" modified="2010-01-19" version="1">MVRWTMYPLLCGLLMGCVTVNENGGTTQEFNSTEAAEARITLGLGYLQAGQWQRAKENLDLALKYAPKYYRAQNAMAFYYQKVDENAKAEAMYKKALQDSPKNGDVLNNYGVFLCSEARYDEAINAFEQAIKQPYYYLTSASYENAGLCSVKKGDLKQARFFFEKSLTHDPNRPKSMLQLAQLDIDAHHLSDARVQLFKFNKRYGYQPDSLWLLIQLERKAGKTTQVAKYAGLLKKEFPDSQQYQNYLANE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZN8</accession>
    <name>D0YZN8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Formate dehydrogenase O gamma subunit</fullName>
            <ecNumber evidence="11">1.2.1.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">VDA_002751</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the formate dehydrogenase gamma subunit family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.2" evidence="11"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002751"/>
    <dbReference type="EnsemblBacteria" id="EEZ41719">
        <property type="protein sequence ID" value="EEZ41719"/>
        <property type="gene ID" value="VDA_002751"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2864">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009326">
        <property type="term" value="C:formate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008863">
        <property type="term" value="F:formate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011577">
        <property type="entry name" value="Cyt_b561_bac/Ni-Hgenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016174">
        <property type="entry name" value="Di-haem_cyt_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006471">
        <property type="entry name" value="Formate_DH_gsu"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01292">
        <property type="entry name" value="Ni_hydr_CYTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81342">
        <property type="entry name" value="SSF81342"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01583">
        <property type="entry name" value="formate-DH-gamm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="75"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="105"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="Ni_hydr_CYTB" evidence="10">
        <location>
            <begin position="9"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ41719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="165" mass="18816" checksum="6321BCD1B680CDAA" modified="2010-01-19" version="1">MYGTPQLARILHPFGAIIMTVGLFFLAARYWKYNHFEKGDMQWMLSVKDVLTENEDKVPPAGHYNAGQKMILRQFLACGVLLLVSGIVAWRAYFSADFSIDTVRIALIVHSIAAFVFCLSLIIHAYMAYWVQGSIDGMLEGKVSLAWAKKHHPRWFRELEAGKKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZP8</accession>
    <name>D0YZP8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002761</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300930.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002761"/>
    <dbReference type="EnsemblBacteria" id="EEZ41729">
        <property type="protein sequence ID" value="EEZ41729"/>
        <property type="gene ID" value="VDA_002761"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1874">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="469334at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009341">
        <property type="term" value="C:beta-galactosidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004565">
        <property type="term" value="F:beta-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032267">
        <property type="entry name" value="DUF4832"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013529">
        <property type="entry name" value="Glyco_hydro_42_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16116">
        <property type="entry name" value="DUF4832"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02449">
        <property type="entry name" value="Glyco_hydro_42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro_42" evidence="1">
        <location>
            <begin position="76"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4832" evidence="2">
        <location>
            <begin position="308"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="501" mass="58472" checksum="2BB959950060CE87" modified="2010-01-19" version="1">MSILNKNFIQISLISLLVPITSHGMSIEHSPKESYEIITNPDIGITDHQTINIRNNKDWNIPSYPETSVVYYRWYWEELEPEKGKYNFKLIDDTINEAKKLNKKIVIRFMTLAGLNETYYEDSPRAGKKILGIPCWLKQQIDPKSKNGCQNDNSFVVNYTDPKFKKSLQNFITAMGNRYNNNSNILRLDVGLIGTWGEWHLGTHKKYSQSTLGFSGYKNKDLTPYIDIMMNAFPNHMLTIDLGTTDDHFTSYATKRNLGWRADCFGDWRPGWNHMQQAYPETFQHIKKDKSSKNDTDPYFLTRWKKAPVDFEICETMKEWDEQPKIYTKKKVEQTFDDALSLHVSLMNLKSDPIPKKYQKILNQFLTKIGYRFVLEHIKITSDFQKNTPITITSQWKNVGVAPSYNNYPITWRIVNSKGEVITYYDTKNDITNWLPSEKLNDTAPIYTQKNTFTLPKTIKTGKYLLEVGLVKPGTHEAIIGLAIENKNKNRWYQLQEFNIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZZ4</accession>
    <name>D0YZZ4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000340</name>
        <name evidence="5" type="ORF">VDA_002857</name>
        <name evidence="6" type="ORF">VDA_003051</name>
        <name evidence="7" type="ORF">VDA_003182</name>
    </gene>
    <organism evidence="5 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301216.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39322">
        <property type="protein sequence ID" value="EEZ39322"/>
        <property type="gene ID" value="VDA_000340"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41825">
        <property type="protein sequence ID" value="EEZ41825"/>
        <property type="gene ID" value="VDA_002857"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ42018">
        <property type="protein sequence ID" value="EEZ42018"/>
        <property type="gene ID" value="VDA_003051"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ42149">
        <property type="protein sequence ID" value="EEZ42149"/>
        <property type="gene ID" value="VDA_003182"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3385">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1254910at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024473">
        <property type="entry name" value="Transposases_IS4_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13006">
        <property type="entry name" value="Nterm_IS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nterm_IS4" evidence="3">
        <location>
            <begin position="17"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="DDE_Tnp_1" evidence="2">
        <location>
            <begin position="125"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="416"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ42018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ42149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="435" mass="50170" checksum="F0E81F7750AFE4F7" modified="2010-01-19" version="1">MDVSQALNVINNWKSDNIETLSDLLPIELIDEAYSLTDTVTMRKRKLTLESMVWLLVGMAIYNNKSMKDLVNQLDIVDRTGKAFVAPSALTQRRKTLGEDAIKAVFERMTNSWLKSANLPHWNGLTLLSVDGVVWRTPDNQENEEAFSRQKGTQYPQVRMVCQMELSSHLITASAFDNYNTNEMVLAEKLIETTPDHSVTMFDKGFYSLGLLDKWHTTGTERHWLIPLKKNVQYEVIRPLGRNDKLILLHSNPRARKLWPNLPSSITARLVTRKIKGKDYQVLTSMIDPLRYPSNDIAALYEHRWEIELGYREQKQYMLGNRLTLRSRLPELVRQELWGILLTYNLIRYQMVELCFNLKGNYLPYQLSFNGTLAHVSALLVGLPYSSPGAIPRQLKGFHAMAESLILEGRRERSFPRAVKPRPQRYPKKKNAVHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z018</accession>
    <name>D0Z018_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 11">Homoserine kinase</fullName>
            <shortName evidence="11">HK</shortName>
            <shortName evidence="11">HSK</shortName>
            <ecNumber evidence="4 11">2.7.1.39</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">thrB</name>
        <name evidence="14" type="ORF">VDA_002881</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>ATP + L-homoserine = ADP + H(+) + O-phospho-L-homoserine</text>
            <dbReference type="Rhea" id="RHEA:13985"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57476"/>
            <dbReference type="ChEBI" id="CHEBI:57590"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.39"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 4/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the GHMP kinase family. Homoserine kinase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.39" evidence="4 11"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301266.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002881"/>
    <dbReference type="EnsemblBacteria" id="EEZ41849">
        <property type="protein sequence ID" value="EEZ41849"/>
        <property type="gene ID" value="VDA_002881"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0083">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="610857at2"/>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00064"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004413">
        <property type="term" value="F:homoserine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00384">
        <property type="entry name" value="Homoser_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013750">
        <property type="entry name" value="GHMP_kinase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006203">
        <property type="entry name" value="GHMP_knse_ATP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000870">
        <property type="entry name" value="Homoserine_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08544">
        <property type="entry name" value="GHMP_kinases_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000676">
        <property type="entry name" value="Homoser_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="SSF55060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00191">
        <property type="entry name" value="thrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00627">
        <property type="entry name" value="GHMP_KINASES_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 11 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0791">Threonine biosynthesis</keyword>
    <keyword evidence="6 11 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GHMP_kinases_N" evidence="12">
        <location>
            <begin position="90"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="GHMP_kinases_C" evidence="13">
        <location>
            <begin position="227"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="97"/>
            <end position="107"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEZ41849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="318" mass="34435" checksum="600E1B247CB0C5B6" modified="2010-01-19" version="1">MSVVVYAPASIGNVSVGFDVLGAAVSPIDGTLLGDRVAVTEGEQPFALHCVGRFVDKLPQQATDNIVYRCWQVFARELDKRNLVLLPVTVTLEKNMPIGSGLGSSACSIVAALDALNQFHGNPLDQEALLALMGEMEGEISGSLHYDNVAPCYLGGLQFMVESQDIISQSIPCFEHWYWVMAYPGITVSTAEARAILPAQYRRQDVIAHGRHLAGFIHGCYSGQAKLAASMIKDVVAEPYRERLLPGFSQAREYALSAGALACGISGSGPTLFSICDDIEVAQRVAKWLQEHYVQNEQGFVHVCRLDKQGSKMTGSDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z035</accession>
    <name>D0Z035_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Hypothetical membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_002898</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301296.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002898"/>
    <dbReference type="MEROPS" id="M23.014"/>
    <dbReference type="EnsemblBacteria" id="EEZ41866">
        <property type="protein sequence ID" value="EEZ41866"/>
        <property type="gene ID" value="VDA_002898"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0739">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1891666at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042834">
        <property type="term" value="F:peptidoglycan binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045834">
        <property type="entry name" value="Csd3_N2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007340">
        <property type="entry name" value="Opacity-associatedA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19425">
        <property type="entry name" value="Csd3_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04225">
        <property type="entry name" value="OapA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="OapA" evidence="7">
        <location>
            <begin position="76"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="Csd3_N2" evidence="8">
        <location>
            <begin position="169"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M23" evidence="6">
        <location>
            <begin position="299"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF19425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="433" mass="48581" checksum="96282CB5241A52FB" modified="2010-01-19" version="1">MLGTTVARLPRMHKILIATVAIGMVIVGLWPTPSTESHSAKTNKEAKYKVGQHYPLYIAITDNDDRPTTNLKNQLDWRYHTIRRGETLAIAFDKMGLSGQELHRLLQDDKGAKQLTELTPGDTLEFGFEPSGQLTHITLKQSPIKTLVVEKQDDGQFESRIEQKAVDTHTNFAQATISSSFWSAADKAGLTANQIMEIAGIFGWDIDFALDIRAGDKFAVLYEEHFVDGERIDRGNILAATFTNMGQTFTAVRSKDGSYYSQDGEAMRKAFLRSPINFRYVSSNFNPRRLHPVTGKVKAHRGTDYVAPIGTPIWSAGDGIVMESSYNRFNGNYVFVRHSSKYVTKYLHMTKRSVKKGQRVKQGQVVGTLGGTGRVTGPHLHYEFLVNGIHKNPRTVQLPQAEALHGKKKAEFKQMANKRMEQISLLKTLYAYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z040</accession>
    <name>D0Z040_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribosomal RNA small subunit methyltransferase C</fullName>
            <ecNumber evidence="1">2.1.1.172</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">16S rRNA m2G1207 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">rRNA (guanine-N(2)-)-methyltransferase RsmC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rsmC</name>
        <name evidence="4" type="ORF">VDA_002903</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>guanosine(1207) in 16S rRNA + S-adenosyl-L-methionine = H(+) + N(2)-methylguanosine(1207) in 16S rRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42736"/>
            <dbReference type="Rhea" id="RHEA-COMP:10213"/>
            <dbReference type="Rhea" id="RHEA-COMP:10214"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74481"/>
            <dbReference type="EC" id="2.1.1.172"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. RsmC family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.172" evidence="1"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301311.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002903"/>
    <dbReference type="EnsemblBacteria" id="EEZ41871">
        <property type="protein sequence ID" value="EEZ41871"/>
        <property type="gene ID" value="VDA_002903"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2813">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1027015at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052914">
        <property type="term" value="F:16S rRNA (guanine(1207)-N(2))-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01862">
        <property type="entry name" value="16SrRNA_methyltr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013675">
        <property type="entry name" value="Mtase_sm_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023543">
        <property type="entry name" value="rRNA_ssu_MeTfrase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007848">
        <property type="entry name" value="Small_mtfrase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05175">
        <property type="entry name" value="MTS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08468">
        <property type="entry name" value="MTS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MTS_N" evidence="3">
        <location>
            <begin position="7"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="MTS" evidence="2">
        <location>
            <begin position="170"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="339" mass="37572" checksum="E976EE58250D82EE" modified="2010-01-19" version="1">MSYSAASQVVARQTAFFEDRKVLVVGELNDSYPAELVGVAQSVAIFTTNYGYYSEMQRYQKVSSYFGAELTADLDIDMVLVYWPKAKAEADYLLTMLIDKFGVDTEFCIVGENRCGVRSAEKMFAQYGPITKYDSARRCSFYWGKCDQKGKPFVVAEWFRSYPISIAGVELTVRSLPGVFSHGEFDKGSELLLNNLPQLHGKVLDFGCGAGVIGAVMKAKYPEIDVELCDISALAIESAKETFKVNNLTGSFTATDVYKTLTGPYQFLISNPPFHAGLKTFYAATENFIAQAPEYLAENGQLVIVANSFLQYPPLIEQSLGQCEVTASTNKFNIYKAVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z051</accession>
    <name>D0Z051_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">GlcNAc phosphomutase</fullName>
            <ecNumber evidence="10">5.4.2.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_002914</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.3" evidence="10"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301330.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002914"/>
    <dbReference type="EnsemblBacteria" id="EEZ41882">
        <property type="protein sequence ID" value="EEZ41882"/>
        <property type="gene ID" value="VDA_002914"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1109">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="637615at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004610">
        <property type="term" value="F:phosphoacetylglucosamine mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005845">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005846">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005843">
        <property type="entry name" value="A-D-PHexomutase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005841">
        <property type="entry name" value="Alpha-D-phosphohexomutase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02879">
        <property type="entry name" value="PGM_PMM_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02880">
        <property type="entry name" value="PGM_PMM_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00408">
        <property type="entry name" value="PGM_PMM_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00509">
        <property type="entry name" value="PGMPMM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="SSF53738"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="SSF55957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PGM_PMM_I" evidence="7">
        <location>
            <begin position="2"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_II" evidence="8">
        <location>
            <begin position="162"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_III" evidence="9">
        <location>
            <begin position="267"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_IV" evidence="6">
        <location>
            <begin position="419"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ41882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="470" mass="52018" checksum="7760DB3F669ED848" modified="2010-01-19" version="1">MIQFGTGGWRAIIGDEFTKDNVRLVAQALANIMTAEAVTDNGFVIGFDRRFLSDKAAKWFAEVLAGNGIKVSFINKYVPTPIVMFKSRQIGATYSACITASHNPADYNGIKVFIEGGRDADEIITQKIEQQIATLQSDQIQYVDFEQAEHDQLIEIINPMNEFVDSIIDFIDIEAIKKANLRVLIDPMFGVAKNALQTVLISGRCDVDVINDGQNPSFGGLMPSPSAATLYRLKHLVAHESYDIGIGTDGDADRLGIIDEKGNFIHPNEVLLLLYYYLLEYKGWQGSVVRNIATTHLLDKVAAAYGEKCFEVPVGFKHISAQMEADDSLIGGESSGGLTIRGHIKGKDGVFASSLLVEMISVTGKKLSELLDEIYGKYGYTYTAEGDCTFKASDRERLYNKIYVEKALPEFAYEVEKVSYADGAKVYFKNGGWALARFSGTEPLLRLFVEMEDKDQAEAVLLQLKSFLHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0I3</accession>
    <name>D0Z0I3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 16">Fumarate reductase flavoprotein subunit</fullName>
            <ecNumber evidence="6 16">1.3.5.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">VDA_003047</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>a menaquinone + succinate = a menaquinol + fumarate</text>
            <dbReference type="Rhea" id="RHEA:27834"/>
            <dbReference type="Rhea" id="RHEA-COMP:9537"/>
            <dbReference type="Rhea" id="RHEA-COMP:9539"/>
            <dbReference type="ChEBI" id="CHEBI:16374"/>
            <dbReference type="ChEBI" id="CHEBI:18151"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="EC" id="1.3.5.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 16">
            <text>a quinone + succinate = a quinol + fumarate</text>
            <dbReference type="Rhea" id="RHEA:40523"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.3.5.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 16">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="16">Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell inner membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
            <orientation evidence="4">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
            <orientation evidence="3">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 16">Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.3.5.4" evidence="6 16"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301684.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003047"/>
    <dbReference type="EnsemblBacteria" id="EEZ42014">
        <property type="protein sequence ID" value="EEZ42014"/>
        <property type="gene ID" value="VDA_003047"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1053">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="153138at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102040">
        <property type="term" value="F:fumarate reductase (menaquinone)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009061">
        <property type="term" value="P:anaerobic respiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022900">
        <property type="term" value="P:electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.700.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-binding_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003952">
        <property type="entry name" value="FRD_SDH_FAD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037099">
        <property type="entry name" value="Fum_R/Succ_DH_flav-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015939">
        <property type="entry name" value="Fum_Rdtase/Succ_DH_flav-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005884">
        <property type="entry name" value="Fum_red_fp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030664">
        <property type="entry name" value="SdhA/FrdA/AprA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011280">
        <property type="entry name" value="Succ_DH/Fum_Rdt_flav_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027477">
        <property type="entry name" value="Succ_DH/fumarate_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014006">
        <property type="entry name" value="Succ_Dhase_FrdA_Gneg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11632">
        <property type="entry name" value="PTHR11632"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11632:SF53">
        <property type="entry name" value="PTHR11632:SF53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02910">
        <property type="entry name" value="Succ_DH_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46977">
        <property type="entry name" value="SSF46977"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56425">
        <property type="entry name" value="SSF56425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01176">
        <property type="entry name" value="fum_red_Fp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01812">
        <property type="entry name" value="sdhA_frdA_Gneg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00504">
        <property type="entry name" value="FRD_SDH_FAD_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="12 16" id="KW-0249">Electron transport</keyword>
    <keyword evidence="11 16" id="KW-0274">FAD</keyword>
    <keyword evidence="10 16" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="13 16 19" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 16" id="KW-0813">Transport</keyword>
    <feature type="domain" description="FAD_binding_2" evidence="17">
        <location>
            <begin position="7"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="domain" description="Succ_DH_flav_C" evidence="18">
        <location>
            <begin position="453"/>
            <end position="581"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00008040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00014044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU362050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF02910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EEZ42014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="602" mass="66515" checksum="4825F941799FFDF4" modified="2010-01-19" version="1">MKTITTDIAVIGAGGAGLRAAIAAAEANPDLEIALISKVYPMRSHTVAAEGGSAAVIKDEDSLDNHFNDTVGGGDWLCEQDVVEYFVENATREMTQLEQWGCPWSRKENGEVNVRRFGGMKVERTWFAADKTGFHMLHTLFQTSIKYTQINRFDEYFVVDLLVDEGQVQGLVAIHMSEGELICIKAKSVILATGGAGRVYNCNTNGGIVTGDGMAMAYRHGVPLRDMEFVQYHPTGLPGTGILMTEGCRGEGGIIVNKNGYRYLQDYGMGPETPVGEPKNKYMELGPRDKVSQAFWHEQQKGNTIKHPLGDVVHLDLRHLGEEYLHERLPFICELAKAYVNVDPAKEPIPIRPTVHYTMGGIETNSHNETRIKGLFAVGECSSVGLHGANRLGSNSLAELVVFGRLAGEGAAERASEFKGWNDAAIAEQIQAVQDRIDVLMNQEGNENWADIRTEMGHTMEAGCGIYRQEDLMQATIDKLAELRERYKHISIKDKGKVFNTDLLYAIEIGYGLEVAQAMVHSAILRRESRGAHQRLDEGCTERDDQNFLKHTLAYYNGDEAPRIEYSDVTITKSQPKARLYGAAAEEAAAKEAAEQQEKEQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0J3</accession>
    <name>D0Z0J3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_003057</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301712.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003057"/>
    <dbReference type="EnsemblBacteria" id="EEZ42024">
        <property type="protein sequence ID" value="EEZ42024"/>
        <property type="gene ID" value="VDA_003057"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1148945at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ42024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="353" mass="41428" checksum="C22AD1F04EFDC9E0" modified="2010-01-19" version="1">MDNLRLQKFKDISIDDKFFGSLKESYKEFSDWFHKKAEDSALVLYNEQNEIEGFLFCKFECGPGDDTTPLLPDSNHMKVGTFKFNPQGTRRGDRYLKKIFDYALAHSSNVQDIYVTVFEEKHGYLVNLFNRYGFEHYGTKPSKNGVEQVLLRDLNKTHNDVDKDYPFIHCKDSRKYLLGIYPEHHTKLFPDSRLFTESPNIVKDISHSNSIHKIYICQMRAVMELQRGDVIVIYRTGDGRGAAEYRAVATSLCVVEGVHTIDTYENEEHFVSECVKFSVFSEKELRQIYRERRYNYVINFTYNVALPKRPIRKTLAEQVGLNREDRWGFLELSDQQFQELIRVAEVDPKFIRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0L3</accession>
    <name>D0Z0L3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cystathionine beta-lyase (CBL) (Beta-cystathionase) (Cysteine lyase)/maltose regulon modulator</fullName>
            <ecNumber evidence="2">4.4.1.8</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003077</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="4.4.1.8" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301793.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003077"/>
    <dbReference type="EnsemblBacteria" id="EEZ42044">
        <property type="protein sequence ID" value="EEZ42044"/>
        <property type="gene ID" value="VDA_003077"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1168">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1462898at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004121">
        <property type="term" value="F:cystathionine beta-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027619">
        <property type="entry name" value="C_S_lyase_PatB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04350">
        <property type="entry name" value="C_S_lyase_PatB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="1">
        <location>
            <begin position="30"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="390" mass="44155" checksum="BEBC09C5611DC349" modified="2010-01-19" version="1">MFDFSTPVNRYGTYCTQWDYVQDRFGQADLLPFTISDMDFETAPCIQQALTERLEHGVLGYSRWNHDDYKQAVCGWFKRRYQAELQAEDLVYGPSVIYIVSQLITLWSEKDEGILVLTPAYDAFGNMIAANQRQMLACPLLKTAQSYEIDWDVFLQQAQRSECKVLLLCSPHNPTGRVWRRDELERMAEICAQHKVKVISDDIHMDMAFASYIPWSKVAQDNQWAIVSSGSKSFNIPALTGAYAFIADASTQQRYLTILKAAHGLSSPAILSVIAHISAYNHGEAWLDELTAYLQNNLHYVASELNSAFPAINYRVPDGTYLAWIDLNPLQIDMDRLQQCLIEKHKVAIMRGDTYGDEGIGYLRLNVGCPRSKVEAGVKALIAALQELVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0N0</accession>
    <name>D0Z0N0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">50S ribosomal protein L10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rplJ</name>
        <name evidence="7" type="ORF">VDA_003094</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the universal ribosomal protein uL10 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301842.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003094"/>
    <dbReference type="EnsemblBacteria" id="EEZ42061">
        <property type="protein sequence ID" value="EEZ42061"/>
        <property type="gene ID" value="VDA_003094"/>
    </dbReference>
    <dbReference type="GeneID" id="57340427"/>
    <dbReference type="eggNOG" id="COG0244">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1470978at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd05797">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00362">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022973">
        <property type="entry name" value="Ribosomal_L10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043141">
        <property type="entry name" value="Ribosomal_L10-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001790">
        <property type="entry name" value="Ribosomal_L10P"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11560">
        <property type="entry name" value="PTHR11560"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00466">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160369">
        <property type="entry name" value="SSF160369"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ42061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="164" mass="17515" checksum="2826AD1C5D496CD9" modified="2010-01-19" version="1">MALNLQDKKAIVAEVNEAANGALSAVVADSRGVAVGAMTTLRKQARENGVYLKVVRNTLARRAVEGTDFECLQDVFVGPSLIGFSNEHPGAAARLFKDFAKENKDFEIKAAAFEGAIANVEVLATLPTYDEAIARLMMCMKEASAGKLVRTIAAVRDQKEEAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0Q5</accession>
    <name>D0Z0Q5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Type II secretion system core protein G</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">VDA_003119</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the GSP G family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003119"/>
    <dbReference type="EnsemblBacteria" id="EEZ42086">
        <property type="protein sequence ID" value="EEZ42086"/>
        <property type="gene ID" value="VDA_003119"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2165">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000983">
        <property type="entry name" value="Bac_GSPG_pilin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013545">
        <property type="entry name" value="T2SS_protein-GspG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010054">
        <property type="entry name" value="Type2_sec_GspG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08334">
        <property type="entry name" value="T2SSG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00813">
        <property type="entry name" value="BCTERIALGSPG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01710">
        <property type="entry name" value="typeII_sec_gspG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSG" evidence="12">
        <location>
            <begin position="35"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF08334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ42086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="151" mass="16676" checksum="697FC293E74F3538" modified="2010-01-19" version="1">MEKAEMQQKQRGFTLLEVMVVIVILGVLASLVVPNLLGNKEKADQQKVVTDISALEQSLDMYKLDNSVYPTTDQGLEALVSKPSSSPEPRNYREGGYIKRLPQDPWGNDYQYVAPGEHGAVDIFSLGADGQEGGEGINTDIGNWNMLDYKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0T2</accession>
    <name>D0Z0T2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Probable GTP-binding protein EngB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">engB</name>
        <name evidence="10" type="ORF">VDA_003146</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Necessary for normal cell division and for the maintenance of normal septation.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301998.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003146"/>
    <dbReference type="EnsemblBacteria" id="EEZ42113">
        <property type="protein sequence ID" value="EEZ42113"/>
        <property type="gene ID" value="VDA_003146"/>
    </dbReference>
    <dbReference type="GeneID" id="57340626"/>
    <dbReference type="eggNOG" id="COG0218">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1746051at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000917">
        <property type="term" value="P:division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01876">
        <property type="entry name" value="YihA_EngB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00321">
        <property type="entry name" value="GTPase_EngB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030393">
        <property type="entry name" value="G_ENGB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019987">
        <property type="entry name" value="GTP-bd_ribosome_bio_YsxC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03598">
        <property type="entry name" value="GTPase_YsxC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51706">
        <property type="entry name" value="G_ENGB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="8" id="KW-0132">Cell division</keyword>
    <keyword evidence="6 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0717">Septation</keyword>
    <feature type="domain" description="EngB-type G" evidence="9">
        <location>
            <begin position="26"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ42113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="221" mass="24593" checksum="816F6E347B1AE66E" modified="2010-01-19" version="1">MNQPLNYRKTHFITSAPDIRHLPQDSGVEIAFAGRSNAGKSSALNRITEQKSLARTSKTPGRTQLINMFEVESGCNLIDLPGYGFAQVPLEMKIKWQKSLGEYLQKRECLAGLVVLMDIRHPLKDLDQQMIYWGVESGLPVLVLLTKADKLKSGARKAQVLKVRKDLADVAGDVQVEAFSSLKGIGVDQVRHKLDAWFGPELERQRMLAAMEAGEEYDAGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0X0</accession>
    <name>D0Z0X0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribosomal RNA large subunit methyltransferase J</fullName>
            <ecNumber evidence="1">2.1.1.266</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">23S rRNA (adenine(2030)-N6)-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">23S rRNA m6A2030 methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rlmJ</name>
        <name evidence="2" type="ORF">VDA_003184</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Specifically methylates the adenine in position 2030 of 23S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>adenosine(2030) in 23S rRNA + S-adenosyl-L-methionine = H(+) + N(6)-methyladenosine(2030) in 23S rRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:43736"/>
            <dbReference type="Rhea" id="RHEA-COMP:10668"/>
            <dbReference type="Rhea" id="RHEA-COMP:10669"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74449"/>
            <dbReference type="EC" id="2.1.1.266"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RlmJ family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.266" evidence="1"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003184"/>
    <dbReference type="EnsemblBacteria" id="EEZ42151">
        <property type="protein sequence ID" value="EEZ42151"/>
        <property type="gene ID" value="VDA_003184"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2961">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036307">
        <property type="term" value="F:23S rRNA (adenine(2030)-N(6))-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00934">
        <property type="entry name" value="23SrRNA_methyltr_J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007473">
        <property type="entry name" value="RlmJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37426">
        <property type="entry name" value="PTHR37426"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04378">
        <property type="entry name" value="RsmJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="1">
        <location>
            <begin position="171"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="192"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="site" description="Interaction with substrate rRNA" evidence="1">
        <location>
            <position position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="307" mass="35233" checksum="5C03B81FCE411785" modified="2010-01-19" version="1">MCCAGYLAIIRHNTALAILLTNLRVSNPMLSYRHSFHAGNHADVVKHIVQSLILDALKQKDKPFVYHDTHSGVGRYDLQDERSEKTGEYKDGIAKIWQQHDLPTEIQSYLDAITALNKGDVLRYYPGSPRVARAQIREQDRMVLTELHPNDFPLLLQEFRGDRQVKMFKEDGFARLKASLPPKERRGVVLIDPPYELKHEYMDVVNAIKDSYQRWATGTYAIWYPVVYRENITKMIKGLEKLGIRKILQIELGVAPDSDERGMTASGMIVINPPWKLESQMQAILPWLQQAIAPETGHHLVEWIVPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0X9</accession>
    <name>D0Z0X9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Carbonic anhydrase family 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_003193</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302122.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003193"/>
    <dbReference type="EnsemblBacteria" id="EEZ42160">
        <property type="protein sequence ID" value="EEZ42160"/>
        <property type="gene ID" value="VDA_003193"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0663">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1242595at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ42160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="183" mass="20214" checksum="E24733B62AD8C176" modified="2010-01-19" version="1">MTFTTQADIRQYQNYQPRISKNTYIDPSATVIGQVELAPHCSIWPQVVIRGDVNYIKIGRESNIQDGSVLHVSRPSPQHPNGFPLLIGEQVTVGHKAMLHGCTIGNRVLIGMGTIILDGAIIEDEIIIGAGSVIPPNKHLLSGYLYLGNPIRQVRQLSDAEKSSLTLSANNYVRLKDEYQLNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z105</accession>
    <name>D0Z105_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_003219</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302196.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003219"/>
    <dbReference type="EnsemblBacteria" id="EEZ42186">
        <property type="protein sequence ID" value="EEZ42186"/>
        <property type="gene ID" value="VDA_003219"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502ZC4M">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="627054at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ42186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="780" mass="88769" checksum="9324C744546ECD79" modified="2010-01-19" version="1">MNVKILNELSLLKTALSVEYSNYLTLAAESSIDSTKIQSTLNIYAAFCYLVKQGNYSALEILNDSSSLNAHFQSLIGFVYNYDDITIKHRYVIGNLLKNLFCYIAQDKHLTLDEVKLSVVKITEEASSCLAQFRELNIDKSKSDYLDGWQVLSKEGKEHEAHLDTLYVNFGEAFTNKVHLALKNYAFTQKSSSLTSALNALKKLFVGISTVYTDRDGLTIETLLSRNYVQLLFHKVFKVLFVRSQAAHNCPKDFHIKWRNAITYYTECFINTGVFAEPHKPFIVPDWKDPKDAAPTFSIGGNATQPESLRWFANIPLKIKDEEAVSIIQQRVDRDMAHVRHVCLLKFEELLEREDRNKAFQSTGLVKPLSGTAGYEKYKNFVGEDKLENTVATFYAHGIAAKDTAYLQFLGFHGNASQFNTELNLPTKSTLNVLLTLLVIEHPLITPSWLAEWDLFDVNGNMVGYKQVGNQHIAVSYKSRKGSTNAHQEVVLNEFSKSIVEFLIQHTHMSREYLKQKGDVNWRKMILTATAANVIRPYHLNTTLHSANDFYDWLQDETLFDKSSDITLEDAQAISDIHSLRSIRRHRGFQIYLETRSMDAVAEALGHEKKDANLLTSYLPKPLMDFFNARWIRQFQNAILLEAMKDSVHRLDAVNMEAQDIEVFLNNHGISNIPEHLDHGFTQQTTTDSEVSESLGFDKLTYTISTSLLQLLMAIRFVVESHDDEESFLDIVAHWYQSAVFVLDTLSSGKHSADDDLMEMLDIATNNKLDTHLVKEALLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z131</accession>
    <name>D0Z131_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative amino acid ABC transporter permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_003245</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302273.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003245"/>
    <dbReference type="EnsemblBacteria" id="EEZ42212">
        <property type="protein sequence ID" value="EEZ42212"/>
        <property type="gene ID" value="VDA_003245"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0765">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="847343at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010065">
        <property type="entry name" value="AA_ABC_transptr_permease_3TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043429">
        <property type="entry name" value="ArtM/GltK/GlnP/TcyL/YhdX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30614">
        <property type="entry name" value="PTHR30614"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01726">
        <property type="entry name" value="HEQRo_perm_3TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="55"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="90"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="147"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="191"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="8">
        <location>
            <begin position="19"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ42212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="223" mass="24924" checksum="320E6C37D51E6B51" modified="2010-01-19" version="1">MGFDVSYMVSLLPILAKYLTTTLSMALWGMIFALFLALVIALIRIKRIWGLNSLSLLYISFFRGTPLLVQLFLFYYGLPQVIPAFVGLDGYSAAVIGLSLHFAAYMAETIRGAILGIDNSQYEASLAIGMSEQQAMRRIILPQAMRIALPSLMNYFIDMIKSTSLAFALGVPEIMAKAQMEASSSFRFFEAFLAVALIYWLIVIVLTRLQTLAETRLNKAYTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z152</accession>
    <name>D0Z152_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Membrane-fusion protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_003266</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003266"/>
    <dbReference type="EnsemblBacteria" id="EEZ42233">
        <property type="protein sequence ID" value="EEZ42233"/>
        <property type="gene ID" value="VDA_003266"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0845">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HlyD_D23" evidence="2">
        <location>
            <begin position="4"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ42233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="315" mass="34631" checksum="848300D885F5ED00" modified="2010-01-19" version="1">MPSIEAIGFIEPNQGVTITSQVSGIIDKIDFDSGMKVKKDQPLVTLDSDVEKAQLQSNVARLPAAKAKYIRYQELYKKNSISKEAYEDAQASYFSLKADIESQRAQLDRRTIKAPFSGQVGLRNVFLGQYIQPSTDVVRLEDTSVMKLRFTVPQTDISDIHLGQNVEIFVDAYPETPFSGKISAIEPAVNYQSGLIQVQANIPNNDGQLRSGMFARAHIILPTLKDQIILPQTSITYTLYGDNVYIAAKDDKGTLRVKQSVVKTGEHKGDIVHVLDGVKPGDVVVTSGQVRLSNNAKVHVVESDALKSPAETPML</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z172</accession>
    <name>D0Z172_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Deoxyribonuclease TatD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_003286</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302388.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003286"/>
    <dbReference type="EnsemblBacteria" id="EEZ42253">
        <property type="protein sequence ID" value="EEZ42253"/>
        <property type="gene ID" value="VDA_003286"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0084">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="915852at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01310">
        <property type="entry name" value="TatD_DNAse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018228">
        <property type="entry name" value="DNase_TatD-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001130">
        <property type="entry name" value="TatD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01026">
        <property type="entry name" value="TatD_DNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005902">
        <property type="entry name" value="DNase_TatD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01090">
        <property type="entry name" value="TATD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01091">
        <property type="entry name" value="TATD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ42253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="262" mass="29605" checksum="6379887E7342671E" modified="2010-01-19" version="1">MIDIGVNLTNDRFDKDRPELIERAQQAGVTGIVITGTNIEESQHAAELATMWPDYCFSTAGVHPHDAKSVTDLSLAPLRQLALLPQVVAIGECGLDFNRDFSPRPIQEAVFEAQLALAAELNMPVFMHCRDAHERFMAILAPWRDKLPAAVLHCFTGTEQELKQCLALDLHIGITGWVCDERRGLELRDVVKHIPDERLMVETDCPYLLPRDLRPKPKSSRNEPQYLPHIAQVIAQCRGQNPEQLIAQTRINSERFFNIRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z173</accession>
    <name>D0Z173_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 11">Delta-aminolevulinic acid dehydratase</fullName>
            <ecNumber evidence="4 11">4.2.1.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">VDA_003287</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>2 5-aminolevulinate = H(+) + 2 H2O + porphobilinogen</text>
            <dbReference type="Rhea" id="RHEA:24064"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58126"/>
            <dbReference type="ChEBI" id="CHEBI:356416"/>
            <dbReference type="EC" id="4.2.1.24"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 1/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Homooctamer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the ALAD family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.24" evidence="4 11"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302391.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003287"/>
    <dbReference type="EnsemblBacteria" id="EEZ42254">
        <property type="protein sequence ID" value="EEZ42254"/>
        <property type="gene ID" value="VDA_003287"/>
    </dbReference>
    <dbReference type="GeneID" id="57340280"/>
    <dbReference type="eggNOG" id="COG0113">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="677575at2"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00318"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004655">
        <property type="term" value="F:porphobilinogen synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001731">
        <property type="entry name" value="ALAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030656">
        <property type="entry name" value="ALAD_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11458">
        <property type="entry name" value="PTHR11458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00490">
        <property type="entry name" value="ALAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001415">
        <property type="entry name" value="Porphbilin_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00144">
        <property type="entry name" value="DALDHYDRTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01004">
        <property type="entry name" value="ALAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00169">
        <property type="entry name" value="D_ALA_DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="7 11 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 11" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="9">
        <location>
            <position position="204"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="9">
        <location>
            <position position="259"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="244"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001415-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001415-5"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ42254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="345" mass="38186" checksum="899517166278AAE8" modified="2010-01-19" version="1">MAVSIQGSFPARRMRRIRKHDFSRRLMAENQISVNDLIYPMFILEGENRRQSVDSMPGIERLSIDLMVEEVKYLADLGIPAIALFPVVSAEFKSLMAEEAYNTNGLVQQAVRAIKAAAPQMGVITDVALDPFTVHGQDGIIDEEGYVINDITTEILIKQALSHAEAGADVVAPSDMMDGRIGAIREALEEAGHIHTQIMAYSAKYASNYYGPFRDAVGSSGNLKGGDKKTYQMDPANSDEALHEVAMDLNEGADMVMVKPGMPYLDVVRRVKTELQVPTFAYQVSGEYAMHMAAIQNGWLKERETIMESLLCFKRAGADGVLTYFAKRVAEWLAEEGRERGNVLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z191</accession>
    <name>D0Z191_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">Cell division protein FtsX</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">VDA_003305</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Part of the ABC transporter FtsEX involved in cellular division.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Forms a membrane-associated complex with FtsE.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell inner membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003305"/>
    <dbReference type="EnsemblBacteria" id="EEZ42272">
        <property type="protein sequence ID" value="EEZ42272"/>
        <property type="gene ID" value="VDA_003305"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2177">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004513">
        <property type="entry name" value="ABC_transpt_FtsX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040690">
        <property type="entry name" value="FtsX_ECD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47755">
        <property type="entry name" value="PTHR47755"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18075">
        <property type="entry name" value="FtsX_ECD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003097">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="9 12" id="KW-0132">Cell division</keyword>
    <keyword evidence="9" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="157"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="209"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="255"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX_ECD" evidence="11">
        <location>
            <begin position="47"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR003097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF18075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ42272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="289" mass="32147" checksum="DB11C791965DA56E" modified="2010-01-19" version="1">MKDMFRRPLGNILTLLVLAFALTLPATFYLLAKNVTIVAQSWQNPTQLTLYLQNSVPEAQAKTFADELKGWPEVETVEFISPQQGLEEFRQNAGFAKAIALLDSNPLPSVVIIKPKPQWQSNEQAQVLATKLRDQQQVSEVRLDSDWLQRLAAIKDLAVTLALVMSGLMLFAVFLIVGNTLRLQVLSHKDEIQVMKMVGATNSYILRPYLYVGVWYGLIASLIAIGLTFAITLLLDQAVATLANLYASHYRLIGLGWDEMLILIMSAAFLGLLAARLSAGRHLREIEPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1A4</accession>
    <name>D0Z1A4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytochrome c oxidase subunit 1</fullName>
            <ecNumber evidence="8">7.1.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_003318</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>4 Fe(II)-[cytochrome c] + 8 H(+)(in) + O2 = 4 Fe(III)-[cytochrome c] + 4 H(+)(out) + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:11436"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="7.1.1.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Energy metabolism; oxidative phosphorylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the heme-copper respiratory oxidase family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.9" evidence="8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003318"/>
    <dbReference type="EnsemblBacteria" id="EEZ42285">
        <property type="protein sequence ID" value="EEZ42285"/>
        <property type="gene ID" value="VDA_003318"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0843">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00705"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045277">
        <property type="term" value="C:respiratory chain complex IV"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004129">
        <property type="term" value="F:cytochrome-c oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015990">
        <property type="term" value="P:electron transport coupled proton transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006119">
        <property type="term" value="P:oxidative phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01663">
        <property type="entry name" value="Cyt_c_Oxidase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.210.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023616">
        <property type="entry name" value="Cyt_c_oxase-like_su1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036927">
        <property type="entry name" value="Cyt_c_oxase-like_su1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000883">
        <property type="entry name" value="Cyt_C_Oxase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023615">
        <property type="entry name" value="Cyt_c_Oxase_su1_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033944">
        <property type="entry name" value="Cyt_c_oxase_su1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014241">
        <property type="entry name" value="Cyt_c_oxidase_su1_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10422">
        <property type="entry name" value="PTHR10422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00115">
        <property type="entry name" value="COX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01165">
        <property type="entry name" value="CYCOXIDASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81442">
        <property type="entry name" value="SSF81442"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02891">
        <property type="entry name" value="CtaD_CoxA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50855">
        <property type="entry name" value="COX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00077">
        <property type="entry name" value="COX1_CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0186">Copper</keyword>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="7" id="KW-0349">Heme</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="127"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="171"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="209"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="269"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="299"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="329"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="361"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="397"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="434"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="475"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="domain" description="COX1" evidence="9">
        <location>
            <begin position="34"/>
            <end position="538"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ42285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="538" mass="59816" checksum="294E1B31B5DEE298" modified="2010-01-19" version="1">MSEIVKPTQQEQNETAIELSADHHHAPAKGLKRWLLTTNHKDIGTLYLLFSLTMFFVGGAMAMVIRAELFQPGLQLVEPNFFNQMTTVHGLIMVFGAVMPAFTGLANWMVPLMIGAPDMALPRMNNWSFWILPFAFSLLLFSLFMEGGGPNFGWTFYAPLSTTYSPPSTGLFVFAIHIMGISSIMGAINVIVTIMNMRAPGMTYMKMPLFVWTWLITAFLLIAVMPVLAGAVTMVLTDKYFGTSFFDAAGGGDPVMFQHIFWFFGHPEVYIMILPSFGIISAIVPAFSRKPLFGYSSMVYATASIAGLSFLVWAHHMFTTGMPVAAELFFMYCTMLISVPTGVKVFNWVATMWRGSITFEVPMLFAIAFIVLFTIGGFSGLMLAITPADFQYHDTYFVVAHFHYVLVSGAIFSIMAAAYYWLPKWTGHMFDERLAKWHFWCSLISVNILFFPMHFLGLAGMPRRIPDYALQFADINAVVSIGGFLFGLSQLLFVAVVIKCIRGGEPAGAKPWEGATGLEWTVPSPAPHHTFSTPPKID</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1A5</accession>
    <name>D0Z1A5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cytochrome c oxidase assembly protein CtaG</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">VDA_003319</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
            <orientation evidence="2">Periplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the COX11/CtaG family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302483.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003319"/>
    <dbReference type="EnsemblBacteria" id="EEZ42286">
        <property type="protein sequence ID" value="EEZ42286"/>
        <property type="gene ID" value="VDA_003319"/>
    </dbReference>
    <dbReference type="GeneID" id="57340240"/>
    <dbReference type="eggNOG" id="COG3175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023471">
        <property type="entry name" value="CtaG/Cox11_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007533">
        <property type="entry name" value="Cyt_c_oxidase_assmbl_CtaG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04442">
        <property type="entry name" value="CtaG_Cox11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005413">
        <property type="entry name" value="COX11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110111">
        <property type="entry name" value="SSF110111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0186">Copper</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009620"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ42286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="198" mass="21601" checksum="EFC6B00F14C19E51" modified="2010-01-19" version="1">MAKQHLRTSLKLGLAACAMFGFAFALVPLYDVFCDITGINGKTSGEQAQQSLQIDTSREVTVEFVAYISPGLQWEFVPEVNQITVHPGANTLVKYRARNLNTQQVVGQAIPSVSPGLAAQYLNKVECFCFNRQPLAGGESAELPLLFYVDPKLPDSISTLTLAYTLFEMKGEENTKTAPSKNATTQVVSLPLTIARNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1B4</accession>
    <name>D0Z1B4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pimeloyl-[acyl-carrier protein] methyl ester esterase</fullName>
            <ecNumber evidence="5">3.1.1.85</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Biotin synthesis protein BioH</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Carboxylesterase BioH</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">bioH</name>
        <name evidence="7" type="ORF">VDA_003328</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>6-carboxyhexanoyl-[ACP] methyl ester + H2O = 6-carboxyhexanoyl-[ACP] + H(+) + methanol</text>
            <dbReference type="Rhea" id="RHEA:42700"/>
            <dbReference type="Rhea" id="RHEA-COMP:9955"/>
            <dbReference type="Rhea" id="RHEA-COMP:10186"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17790"/>
            <dbReference type="ChEBI" id="CHEBI:78846"/>
            <dbReference type="ChEBI" id="CHEBI:82735"/>
            <dbReference type="EC" id="3.1.1.85"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; biotin biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.85" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302500.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003328"/>
    <dbReference type="ESTHER" id="lisda-d0z1b4">
        <property type="family name" value="BioH"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ42295">
        <property type="protein sequence ID" value="EEZ42295"/>
        <property type="gene ID" value="VDA_003328"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1282004at2"/>
    <dbReference type="UniPathway" id="UPA00078"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009102">
        <property type="term" value="P:biotin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01260">
        <property type="entry name" value="Carboxylester"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010076">
        <property type="entry name" value="BioH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01738">
        <property type="entry name" value="bioH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0093">Biotin biosynthesis</keyword>
    <keyword evidence="2 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0719">Serine esterase</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="6">
        <location>
            <begin position="16"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="83"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="144"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="83"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="208"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="236"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="22"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ42295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="256" mass="28007" checksum="9493C3744DCEBACE" modified="2010-01-19" version="1">MAAELFWHTQGQGPDLVLIHGWGMNSAVWQPVMPLLTSHFTVHCCDLPGYGESALPSASSLTEIAKQVYLSAPVEQAAWLGWSLGGLVATEIALRAPERVSHLITVASSPCFAASENWKGIKPAVLQAFMAQLELDFQPTIERFMALQTMGSPSARQDIKQVKQAVLAKPQPQLAALQIGLQLLAEQDLRPQLGAICQPWLRLYGRLDGLVPVKTCTEMERLAPQSQAVVFEQASHAPFISHPEQFIDPLLAFCHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1B7</accession>
    <name>D0Z1B7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_003331</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302506.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003331"/>
    <dbReference type="EnsemblBacteria" id="EEZ42298">
        <property type="protein sequence ID" value="EEZ42298"/>
        <property type="gene ID" value="VDA_003331"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1031685at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="157"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="177"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="237"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ42298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="450" mass="49987" checksum="C615FC250A167142" modified="2010-01-19" version="1">MRLSPHSTLARTIILLAGLLIASQIFSYLTVVNYALLPSIQQFNRILAYEVRLMMKEDLDMADGEKFHLDRPVRRQLLEQLGVTVVAVNSLEAKEFEQATHIDYLSEEMSHELKSPTDVRLLLGADSYELWMHCEAMPNYLLRVPLSALQEDDFSPLIIYSLVIAVMVIVGGWMFIRIQNRPLMALEQAAMQVAKGDIPPPLPVQGASEIRAVTKAFNKMAEGIKQLEDDRALLLAGVSHDLRTPLTRIRLATEMMSPEDGYLAESMIKDTEECNEIISQFMDYLKSTKKQEEEDVELNTLLQEVAEAEGGYERHIEQELGQVPGVVRANTVALKRCVSNLVVNAIRYGDGWIKISSGASADRQTAWFCVEDNGPGIAPDEVTRMFQPLTRGDSARGSDAEGTGLGLAIVKRIIDQHEGTINVTNRSEGGLRVQINLPLANGKGSKLTLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1E9</accession>
    <name>D0Z1E9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional reguator TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_003363</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302573.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003363"/>
    <dbReference type="EnsemblBacteria" id="EEZ42330">
        <property type="protein sequence ID" value="EEZ42330"/>
        <property type="gene ID" value="VDA_003363"/>
    </dbReference>
    <dbReference type="GeneID" id="57340187"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025722">
        <property type="entry name" value="TetR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13972">
        <property type="entry name" value="TetR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="24"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ42330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="213" mass="25049" checksum="8CE7C8F709E5B8BD" modified="2010-01-19" version="1">MKTRDRIILASRELFNEQGESNVTTNHIAAHLGISPGNLYYHFRNKEEIIHCIFDEYAQELSVRFQPQNMDESSDGLLGYLDGVFFLMWRYRFFYANLPDILRRDEVLQVKYLTAQEQLHYNIARLMQNFRQMGLVNLNDEDLQALADTLKLVASSWISYQTTQAPGAKITKKVIYHGVIQMLNIVRPLATEKGRERVEQLREYYNSQQQEHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1L2</accession>
    <name>D0Z1L2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glutathione-regulated potassium-efflux system ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_003426</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302689.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003426"/>
    <dbReference type="EnsemblBacteria" id="EEZ42393">
        <property type="protein sequence ID" value="EEZ42393"/>
        <property type="gene ID" value="VDA_003426"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0488">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1112046at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032781">
        <property type="entry name" value="ABC_tran_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12848">
        <property type="entry name" value="ABC_tran_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="2"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="313"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="530"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="345"/>
            <end position="352"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ42393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="642" mass="73251" checksum="B4BDA524D003443D" modified="2010-01-19" version="1">MITFSDMQLLRGGKILLDNATATIHPGDKVGLVGKNGCGKSTLFALLKDELTLDAGNCQFPNNWEMAWVAQETPALERAAIEYVIDGDREYRDLERQLQHAEEAGNGTKVAELHGKLDAIGGYSIRARAAELLDGLGFSQQQMEWNLTQFSGGWRMRLNLAQALICRSDLLLLDEPTNHLDLDAVMWLEKWLQSYRGTLVLISHDRDFLDPIVNRIIHIENQTMNPYTGNYSSFENQRAEKLVLQQAMFQRQQKQMAHMQSYIDRFRYKASKARQAQSRIKALERMEKVLPAQFDNPFTFEFREPASLPNPILMMDHVCAGYGDNVILDKIRLNLVPGSRIGLLGRNGAGKSTLIKMLAGELPALAGEMRYSQGVKIGYFAQHQLETLYLDDSPLQHMVRLAPEATEQQLRDYLGSFGFNGDKALEKVGPFSGGEKARLVLALIVWQKPNLLLLDEPTNHLDLDMRQALTMALQTFEGAMVIVSHDRYLLRATTDDLYLVHDHQVVPFDGDLHDYHKWLTEQQRIERRELQGNKEGDEVKEHSAANRKEQKRLEAEFRKQTAPLRKEIEKLDKKIEKLSQIISEAETELSDPSIYNAENKVRLAEQLKRQGDAKSELDDVEMDWMDRQEQLEAMEAEFRGES</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1Z5</accession>
    <name>D0Z1Z5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Membrane protein TerC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_001981</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TerC family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299083.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40949">
        <property type="protein sequence ID" value="EEZ40949"/>
        <property type="gene ID" value="VDA_001981"/>
    </dbReference>
    <dbReference type="GeneID" id="57341878"/>
    <dbReference type="eggNOG" id="COG0861">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1917125at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005496">
        <property type="entry name" value="Integral_membrane_TerC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022369">
        <property type="entry name" value="Integral_membrane_TerC_rswitch"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30238:SF0">
        <property type="entry name" value="PTHR30238:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03741">
        <property type="entry name" value="TerC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03718">
        <property type="entry name" value="R_switched_Alx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="34"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="84"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="109"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="135"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="196"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="231"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="258"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="284"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="324" mass="36392" checksum="831483C2192E947A" modified="2010-01-19" version="1">MSLFSYEGFAVLTVLMLALDLYQTRGGAVSIKKAAIWSLFWVVLALLFSVFIYHYWPLMAPDSTYTNAQATTAFLTGYLLEKSLSVDNLFVFALIFGQFMVPERLRPRVLMLGVVGALILRGFMIAVGAELLDQFHWVLYIFAAFLLYTGFKLWKEGDEEPEDFSNSLPVRVVKRFFRVTDDYQEQKMFVKDKKGWLATPLLVVVAVIALTDVMFALDSIPAIFAVTREPFLVYTANVFALLGLRSLYFVLEGMLTRFCYLRVALAFILSFIGVKMLLVGTAWAIPTAVSLCVIALTITAAIVGSLWKTRNQVKVEDKPAAGHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z220</accession>
    <name>D0Z220_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0434 protein VDA_001869</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001869</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0434 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298846.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001869"/>
    <dbReference type="EnsemblBacteria" id="EEZ40837">
        <property type="protein sequence ID" value="EEZ40837"/>
        <property type="gene ID" value="VDA_001869"/>
    </dbReference>
    <dbReference type="GeneID" id="57342007"/>
    <dbReference type="eggNOG" id="COG2835">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1834382at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01187">
        <property type="entry name" value="UPF0434"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005651">
        <property type="entry name" value="Trm112-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03966">
        <property type="entry name" value="Trm112p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="59" mass="6686" checksum="A72C383F2CF232BA" modified="2010-01-19" version="1">MDHRLLEIVACPVCNGKLNYDKDKNELVCKFDRLAYPISDGIPVLLEPEARTLSPEEVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2A2</accession>
    <name>D0Z2A2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Enoyl-CoA hydratase/delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase</fullName>
            <ecNumber evidence="13">1.1.1.35</ecNumber>
            <ecNumber evidence="13">4.2.1.17</ecNumber>
            <ecNumber evidence="13">5.1.2.3</ecNumber>
            <ecNumber evidence="13">5.3.3.8</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">VDA_000553</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a (3S)-3-hydroxyacyl-CoA + NAD(+) = a 3-oxoacyl-CoA + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:22432"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57318"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
            <dbReference type="EC" id="1.1.1.35"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism; fatty acid beta-oxidation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.35" evidence="13"/>
    <dbReference type="EC" id="4.2.1.17" evidence="13"/>
    <dbReference type="EC" id="5.1.2.3" evidence="13"/>
    <dbReference type="EC" id="5.3.3.8" evidence="13"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304704.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000553"/>
    <dbReference type="EnsemblBacteria" id="EEZ39533">
        <property type="protein sequence ID" value="EEZ39533"/>
        <property type="gene ID" value="VDA_000553"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1024">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1250">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="977512at2"/>
    <dbReference type="UniPathway" id="UPA00659"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003857">
        <property type="term" value="F:3-hydroxyacyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008692">
        <property type="term" value="F:3-hydroxybutyryl-CoA epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004165">
        <property type="term" value="F:delta(3)-delta(2)-enoyl-CoA isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004300">
        <property type="term" value="F:enoyl-CoA hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006180">
        <property type="entry name" value="3-OHacyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006176">
        <property type="entry name" value="3-OHacyl-CoA_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006108">
        <property type="entry name" value="3HC_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00725">
        <property type="entry name" value="3HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02737">
        <property type="entry name" value="3HCDH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00067">
        <property type="entry name" value="3HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="13" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="5 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3HCDH_N" evidence="12">
        <location>
            <begin position="316"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="domain" description="3HCDH" evidence="11">
        <location>
            <begin position="495"/>
            <end position="590"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ39533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="715" mass="78603" checksum="B3DF7A8AFA41B522" modified="2010-01-19" version="1">MYQGEYFQLKRNQSFGELILSSTKDSVNTLGKAALEELSIILDTIDQSDLSGLIIRSDKKLFCGGANVKEFRALFAQGEQAVNDYLTWVHSIYNRIEDLDIPKVVVLNGFTAGGGAELALLADYRLMTTDAAVSFPEVKLGIFPGWGGLTRLPRLLGLDTALQWLTTGKKFNASKALTCHFADGVIDSNKQDPVEAAIHVLDSCLKGELDWQERKKEKLSSLRMNQYELGMSVSVAKGMIAKTAGKHYPAPMIMLNAIEKAAGSCRDEALAIEREHLCQCVKTGVADALVSVFLSDMAVKAKTKGFSSEQKPLNDISVLGAGIMGGGIAYVSADKGMHVHLKDINQQGLDLGLEEANKLLAKQVTKKRKTPLAMGQVLNRIQPTLHDISLAETELVIEAVVENPNVKANVLADIEQKAPNALIASNTSTLNISGLANSLQRPENFCGIHFFNPVHRMPLVEVIKGEKTSDETINKAVQYVKQLGKTPIVINDCAGFLVNRCLTPYFLAFNQLLTDGADISIVDKIMTKQFGWPMGPAMLLDVIGLDTTAHCIDVMDDAFPGRLQKPQKNIIQTLVDEGYLGQKNHQGFYQHVADRKGRLKPLRNTQSDELIAKLAASQCEDDAETMMMRLMLPMMFEAVRCLDEGIVASPEEADIAMLYGTGFPAFRGGLFYYMDQLGMEKLISLADTFKHLGTLYQIPEGILNRAQQKQTFYTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2C2</accession>
    <name>D0Z2C2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cobalt-zinc-cadmium resistance protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_000573</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304742.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000573"/>
    <dbReference type="EnsemblBacteria" id="EEZ39553">
        <property type="protein sequence ID" value="EEZ39553"/>
        <property type="gene ID" value="VDA_000573"/>
    </dbReference>
    <dbReference type="GeneID" id="57342945"/>
    <dbReference type="eggNOG" id="COG3965">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="381612at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="SSF161111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="13"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="41"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="119"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="156"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="188"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ39553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="305" mass="34149" checksum="B90B85F10D9CAEF8" modified="2010-01-19" version="1">MATHSRKISKERLALKLSLLGTIWVASLGIGYGLYVGSNAILLDGMFSFLSMGMTGLSLYTAYLVSKPDDEQFQFGYAHIEPLINVVNGLLILVTCLFAFVSGVQTIASGGRDIVIEDALVYAVLSTVSCFGIYFFETYTARSVDSELVRVDSQEWLIDGILSAAILVGFVAVMIFDSLGHSQWNRYVDPILVSTLAIAASVLPISVLRRNVKEVLLVAPQDEVQTHVDTVIAELSETYNFDDYTHHLAKTGRQYDLEVNILIKDDKQWSMKRQDLVRQKIWEKLKDDLGNAWFSVSFTTQERWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2D0</accession>
    <name>D0Z2D0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000581</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304766.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000581"/>
    <dbReference type="EnsemblBacteria" id="EEZ39561">
        <property type="protein sequence ID" value="EEZ39561"/>
        <property type="gene ID" value="VDA_000581"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502ZW1U">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="16364at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="843"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="1040" mass="114936" checksum="880D147785CEFB37" modified="2010-01-19" version="1">MPSDAYNSAEIAGTKSPSSPAGTCPLQTKEVGIIPVRYAIDPTMGTKALFPLPEGDDWQPTFNINLPYTLRQLRDGWLYVYSKKQKVLHTYQIENAVFTAQHEGGTCAACLTYDSDDTLWLSYSHQRWTPRLIELFSTEKKYREQWMRQLNIQAFRLRMKGHHAGMAKKLESSVADIGSVTQDIINGFAITSTPLNADDTESNSGFEFNKAKPANPASTYQVTLPESNVGNGLFIALEDPLADITDIALKLGSLHAQKERVFGSDEDKHKQLISEFVRSIARVPYDPKTAPEALKTKLKDNPQEVLKFESVLNQYLRYQSPLNQAQYGSEAYAANALSYEQPRLEAQKILNNTYHYTPTDKDFEHFESRKKNIDLVDWNKMSIFINEKYAKLKAIEGDAATMLAELNRALKDLGVYAARVGVDIEETQGQLYLNTLFGHLFPLMAAVSQKWDAAEEDTLLALAPFYYSPEFSKAINKAIPNDALSVTNASDMTNMVSRLGESIGFIYDGRIPEGDEATKALITRVIQAAKNAITTAGDHVWDGLMDGLFPHQVSGESGLDSGLRLMVARSLVSKEGKLLISSDYVSKFDSFSDKLNPLLQKAEQLSGQLYANGTTAMRNNLNEIKEKIAKLIADEMPLLIKFEQEAMNDAVRGKLAASIMGLRSRLTSTVGQTVDNVNGVGTVVGGFAAICNLWNLWAVSQQVTSKLNNANSTQDQADVYIELASALSWTLSAFAGVGRDSQVIASKFVEMTVKRALAESASTVNQQVVIKRFVAAAKVTAIFGLFAASTEIYLTGRQWQQSDDTFEQALLIGKIGSLAAQGAVSAFQLARVLGSTALLGEIIAAWMVSTLFYAGIAYLLFSALYNYFHRDEMQKWLLNGAWGKSPKPQTLEQELTALENIIWKPKIELTKNSVDIYLPSYLLNDAKKHFDLQIVVHEKINLIYVSMNSHSNETLKSTQIDVSQAKRKNTANGVGYISVPVLHKEGDEVIIAINYDRAWTEECQSYVGTRSSAGTFDLERTKGVVSKRHGVAGLTLPVAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2F9</accession>
    <name>D0Z2F9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hypothetical ATP-dependent endonuclease of the OLD family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000610</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304860.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000610"/>
    <dbReference type="EnsemblBacteria" id="EEZ39590">
        <property type="protein sequence ID" value="EEZ39590"/>
        <property type="gene ID" value="VDA_000610"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1195">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3593">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="318943at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01026">
        <property type="entry name" value="TOPRIM_OLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022602">
        <property type="entry name" value="DUF2813"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034139">
        <property type="entry name" value="TOPRIM_OLD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11398">
        <property type="entry name" value="DUF2813"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="566" mass="65734" checksum="8D0C914E1A47A9FC" modified="2010-01-19" version="1">MHLERIEISGFRGIKRLSLTFDELSVLIGENAWGKSSLLDALSIALSPDAQFYNFKFSDFHVDYTLGNKKMTQLQIILHWKEDAEGEHIARRYKGFERFWVLKHNIRHLYYQIESVIENDKVITYRRFLNHHGREIHCDENDRMIKRWMVLHPVVRLRDARRLRYYDDENKPLHDSNDHEQLQTNGHSDNHVNGNAQQEARIQKRLDNTCRRLMTQPGHVNSGELKSSIKALHSLVDHYFAFAPHQRQRNFNRAHFPSFAQYAEHPFEQLIPKNLSKQNQLVLLGLLNAFIRARGPVSLKRLSRPILIVEDPEGRLHPTILQQAWSFISSMPMQKILTTNSPELLSSVPLQSIKKLIRQADRTQVFEVGKRTLGKDETRRVSFHVRLHRPSALFARAWLLVEGETEVWLFNELARYCGYNLAAEGVQIIEFAQSGLRPLVKIARSLGIEWHLISDGDMAGRKYAETVRNMLGTDAERHRLTVLPDRDIEHYLYNQGYEALFKQLSGIQGDAPINAHKIIQRALKRHAKPDVALAIVEYTHEGKVDEVPLLIRWLLKRIVAMSRGVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2G4</accession>
    <name>D0Z2G4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">NAD(P) transhydrogenase subunit alpha</fullName>
            <ecNumber evidence="9">7.1.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">VDA_000615</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 9">The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>H(+)(in) + NAD(+) + NADPH = H(+)(out) + NADH + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:47992"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="7.1.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the AlaDH/PNT family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.1" evidence="9"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000615"/>
    <dbReference type="EnsemblBacteria" id="EEZ39595">
        <property type="protein sequence ID" value="EEZ39595"/>
        <property type="gene ID" value="VDA_000615"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3288">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008746">
        <property type="term" value="F:NAD(P)+ transhydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902600">
        <property type="term" value="P:proton transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007886">
        <property type="entry name" value="AlaDH/PNT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007698">
        <property type="entry name" value="AlaDH/PNT_NAD(H)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026255">
        <property type="entry name" value="NADP_transhyd_a"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024605">
        <property type="entry name" value="NADP_transhyd_a_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01262">
        <property type="entry name" value="AlaDh_PNT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05222">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12769">
        <property type="entry name" value="PNTB_4TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000203">
        <property type="entry name" value="NADP_transhydrogenase_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01002">
        <property type="entry name" value="AlaDh_PNT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01003">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00561">
        <property type="entry name" value="pntA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0520">NAD</keyword>
    <keyword evidence="4 9" id="KW-0521">NADP</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="146"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="380"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="402"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="433"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="457"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="domain" description="AlaDh_PNT_N" evidence="12">
        <location>
            <begin position="2"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="AlaDh_PNT_C" evidence="11">
        <location>
            <begin position="124"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR000203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ39595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="490" mass="51799" checksum="C5A300B44764D21E" modified="2010-01-19" version="1">MGFSVAVEHNAGVKASFDDAAYEAAGATVVSTNEVWQSDLIFKVNAPQVNPETGVDEIELIKDGASLVSFIWPAQNPELLEKLSAKNINVMAMDSVPRISRAQALDALSSMANIAGYRAVVEAAHEFGRFFTGQITAAGKVPPAKVLVAGAGVAGLAAIGAAGSLGAIVRAFDVRPEVKEQVESMGAEFLEVDYKEDTSTGDGYAKEMSDEFNKAAERLYAEQAKDVDIIITTALIPGRPAPKLITKEMVDSMKAGSVIVDLAAANGGNCAYTEADKVITTANGVKIIGYTDMVSRLPTQSSQLYATNLVNLVKLLCKEKDGNIDINFDDEVLRGLTVIKAGEVTWPAPPIKVSAAPKKEAAPKVAIAPKVEKPTSPAKKYGILAAAAIAFGWVANNAPAEFLSHFTVFVLACVVGYYVVWNVTHALHTPLMSVTNAISGIIIVGALLQIGQGHSGVSVLAFIAILIASINIFGGFTVTKRMLEMFRKDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2H0</accession>
    <name>D0Z2H0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000621</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304893.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000621"/>
    <dbReference type="EnsemblBacteria" id="EEZ39601">
        <property type="protein sequence ID" value="EEZ39601"/>
        <property type="gene ID" value="VDA_000621"/>
    </dbReference>
    <dbReference type="GeneID" id="57342893"/>
    <dbReference type="eggNOG" id="COG3140">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005371">
        <property type="entry name" value="UPF0181"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03701">
        <property type="entry name" value="UPF0181"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="49" mass="5390" checksum="A942C137DC8262F4" modified="2010-01-19" version="1">MLTLTHSEQQEAAERIHELMAQGISSGEAIKIIADQIRAEAAKKAEQQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-02-10" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2I5</accession>
    <name>D0Z2I5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Riorf46 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000636</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39616">
        <property type="protein sequence ID" value="EEZ39616"/>
        <property type="gene ID" value="VDA_000636"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2801">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1637053at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="2">
        <location>
            <begin position="128"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="408"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="454" mass="53106" checksum="CF7292D1B79ADC24" modified="2010-01-19" version="1">MLLTMTDNELLRIKVIQDICDKRLTGVEAAHLLNLSPRQVYRLVKRFIEFGASGLVSLQRGRPGNHRYDENVKLQTLAILHGHYTDFGPTLAHEKLTERHNIHVSVETIRQWMIADGLWVPHNKRKPRAYQPRYRRDCLGELIQIDGSHHDWFEGRSNKCCLLVFIDDATGKLMNLRFSETESAFDYMVATREYLEQHGKPTAFYSDRHAVFHVSKRDAKTERLTQFGRVLHDLNIELICANSSQAKGRVERANKTLQDRLVKEMRLQEIDTIEQANVWLPNFIADFNRRFAKPAKYPKDMHRPVREMTDELNDIFAWQELRKLSKSLTFQYDKVVYLIDPTEENQRLINQVVKVLDRPDGTIAIQYGLRKLTFKVFDKLTDIDQGQIVDNKRLGAVLKFAQEKQQEFEQQQTRSRSKKAPKRTAQQRAIRQLEAINPVLVHPEQFKPSTRKKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2J0</accession>
    <name>D0Z2J0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Zn_protease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000641</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304942.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000641"/>
    <dbReference type="EnsemblBacteria" id="EEZ39621">
        <property type="protein sequence ID" value="EEZ39621"/>
        <property type="gene ID" value="VDA_000641"/>
    </dbReference>
    <dbReference type="GeneID" id="57342864"/>
    <dbReference type="eggNOG" id="COG4067">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1576021at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008503">
        <property type="entry name" value="Put_Zn_protease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05618">
        <property type="entry name" value="Zn_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="SSF50630"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003020008" description="Zn_protease domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="Zn_protease" evidence="2">
        <location>
            <begin position="30"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="168" mass="18676" checksum="EC42E8ACA28ABD12" modified="2010-01-19" version="1">MKKGLLSTLILLSAVTFGANAASSCDGKEIVGQVETIRVNNLDMDYEARIDTGAATTSINAYDIKVLGSDNSNMRDNLGEQVEFKTKNEKGQVATYKGKIIRVSKIRNAQGVERRYAVVMDLELNGKNKAVAVNLRNRSKLEYKLLIGRNWLNNDYLVDVSIHSKDKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2N6</accession>
    <name>D0Z2N6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Molybdenum transport ATP-binding protein ModC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_000687</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305058.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000687"/>
    <dbReference type="EnsemblBacteria" id="EEZ39667">
        <property type="protein sequence ID" value="EEZ39667"/>
        <property type="gene ID" value="VDA_000687"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4148">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1200451at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032991">
        <property type="term" value="C:protein-containing complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015412">
        <property type="term" value="F:ABC-type molybdate transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011868">
        <property type="entry name" value="ModC_ABC_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004606">
        <property type="entry name" value="Mop_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005116">
        <property type="entry name" value="Transp-assoc_OB_typ1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03459">
        <property type="entry name" value="TOBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02142">
        <property type="entry name" value="modC_ABC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00638">
        <property type="entry name" value="Mop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51866">
        <property type="entry name" value="MOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 6" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="5"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="Mop" evidence="8">
        <location>
            <begin position="296"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="37"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ39667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="364" mass="40800" checksum="ECE0E99D0E4C6C39" modified="2010-01-19" version="1">MNKNITSLQIKIKQQLGDLALDVAVNLPLSGITAIFGRSGAGKTSFINVLSGLTQPDEGAIHLGSHCLVDTARKLCLPPEKRNIGYVFQDARLFPHYTVKGNLNYGCREKDPNHFNDVVKLLGIEALLNRYPASLSGGEKQRVAIGRALLTKPDMLLMDEPLASLDLPRKQELMPYLEQLAKQVNIPIVYVTHSLDEILRLADHMVMLNQGKVVASGHVNSVWGSPEMRPWLPPKEQSSLISARVNYNHPNYALTQVMLSHNAFLWVSRLSLHRGEWGRVRIYSNDVSITRAKPQQTSIRNILRARVDKIHHAEDERVEVKLRVGETHLWANITLWAIDELQLQVGDEVYAQIKGVSVTKDDLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2T2</accession>
    <name>D0Z2T2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF218 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000733</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305195.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000733"/>
    <dbReference type="EnsemblBacteria" id="EEZ39713">
        <property type="protein sequence ID" value="EEZ39713"/>
        <property type="gene ID" value="VDA_000733"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1434">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="758209at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06259">
        <property type="entry name" value="YdcF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003848">
        <property type="entry name" value="DUF218"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02698">
        <property type="entry name" value="DUF218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003020021" description="DUF218 domain-containing protein" evidence="2">
        <location>
            <begin position="22"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="93"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="DUF218" evidence="3">
        <location>
            <begin position="192"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="363" mass="40434" checksum="E6445C538DC5C12C" modified="2010-01-19" version="1">MNKKLITLALSGILYVSPTFALTQTQSAVQSTADYAQVVSKRQVVDQLLEQAVTAFKSPARISHAGFTAKMPSNMEIVTDRLLQAYQLEPYRTDLLISAANAQIYNKNVDRAIELFEQVLSVAPDDVDANAYLAVWQHFKGNNQAANKHLKKLEQLDSGKAADIQRIFETVDRIVATPLKSKMKEPKAGNTAIITLGYALNPDGTMSDILIERLNMTLKIAKEQPNSLIILTGGVPQNNQTEGRLMADWLIKQGINPNRLIEDNYARSTVENALYSSYALARHKIEHATIISSASHVRRGQTLFEIASWQTGPQNITFDTIGAPDKPLEELAKPSQGELLGIYRDALRTYGMWSYRSYPLEQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2T9</accession>
    <name>D0Z2T9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000740</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000740"/>
    <dbReference type="EnsemblBacteria" id="EEZ39720">
        <property type="protein sequence ID" value="EEZ39720"/>
        <property type="gene ID" value="VDA_000740"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1670">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="117" mass="13013" checksum="BEBCFD645A5E8AB8" modified="2010-01-19" version="1">MAMYQTKGMGLLKVTRKEDNKPVGICGLIKRDTLDDIDLGYGFLPEVFRCGYGYEAGRCMMNFAKEALNITRLVAITTSNNVASRALLTKLGFTFEAVQEHQGEHTLDLFSTNLSNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2U0</accession>
    <name>D0Z2U0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MutT/nudix family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000741</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305219.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000741"/>
    <dbReference type="EnsemblBacteria" id="EEZ39721">
        <property type="protein sequence ID" value="EEZ39721"/>
        <property type="gene ID" value="VDA_000741"/>
    </dbReference>
    <dbReference type="GeneID" id="57342747"/>
    <dbReference type="eggNOG" id="COG0494">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1308416at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="134" mass="15102" checksum="C8717023BC0A3690" modified="2010-01-19" version="1">MTLQHIDKLAWILIQDRKLLAVRSFGKTSFYLPGGKRENGESDQEALIREIQEELAVDLKPDSIEYAGFYQAQADGKPEGVMVKMTCYFAQFDGQITPSAEIEEAQWLNSENLDVCSLAAKIIVEDFKQQGLID</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2U7</accession>
    <name>D0Z2U7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Bcr/CflA family efflux transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_000748</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell inner membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Bcr/CmlA family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305240.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000748"/>
    <dbReference type="EnsemblBacteria" id="EEZ39728">
        <property type="protein sequence ID" value="EEZ39728"/>
        <property type="gene ID" value="VDA_000748"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1452500at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990961">
        <property type="term" value="P:xenobiotic detoxification by transmembrane export across the plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004812">
        <property type="entry name" value="Efflux_drug-R_Bcr/CmlA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00710">
        <property type="entry name" value="efflux_Bcr_CflA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="78"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="107"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="168"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="214"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="247"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="279"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="305"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="341"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="371"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="8">
        <location>
            <begin position="12"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ39728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="393" mass="43886" checksum="68A086D71C97DB1A" modified="2010-01-19" version="1">MTHNLYKQQKIALFLVVSISFLMGIGIDLYVPSLPDMAHFYHANISYIQLTISLYLLGYGLGQIILGSLSDSYGRRKIFIASSMVFSISSMLCIVSDSIIYLNLFRLLQGLAIAGLASGMRAIIVDLFSGLELKKMANYFALSWAIGPIVAPFIGANLADKFGWQANFYLFTVYGIILFFVCTLLFKESNKNIIHFNVKNFTTNLVIIITNKDFTLLSIIYGLSYSTVLIFNTVGPYLIEVKLNYSILFYGNLAMFLGCAYFIGTMINRYLIIQYDNKSILQSGIILSSISSIVMLLLMTFHQNIFTLTVPIFAIFVFIGLIVPNAIAITMTLFPKQAGMATSLCGTIVGLIVFSVTYIIGLFKVTPIELAINYISIFIIINFIKYSIPNKKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z373</accession>
    <name>D0Z373_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">APH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000874</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305595.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000874"/>
    <dbReference type="EnsemblBacteria" id="EEZ39854">
        <property type="protein sequence ID" value="EEZ39854"/>
        <property type="gene ID" value="VDA_000874"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3173">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1586922at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="APH" evidence="1">
        <location>
            <begin position="37"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="296" mass="34544" checksum="5255A0AF61087493" modified="2010-01-19" version="1">MNKPQLLNIAKKAYLTMFNTQAEVCDIQETFYGWIVFLVGSKGKIVVKFSKEVGRIAKEANALKRLRTVVDCAVPSIYFFGRDEGYDYLALEWIDGVSASELPKEHHAIKIFSESYSDILVALHEHHNDQGFECNSESFTPDFINAFEQWTMPLHRFIQSGGSPFSGQEREQFGQLWEMRETLLDPIRHTESSLIHDDCNLANVLFDPKTYKAIALLDPCDMGFKHREMDLIHLNHYRSDVPILDCYIEKSPLTENYLIRQEFFRLWDDAKHCRNTGWYNNQWFSTQLSHFIDVVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z391</accession>
    <name>D0Z391_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">2-hydroxy-3-oxopropionate reductase</fullName>
            <ecNumber evidence="5">1.1.1.60</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_000892</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.60" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000892"/>
    <dbReference type="EnsemblBacteria" id="EEZ39872">
        <property type="protein sequence ID" value="EEZ39872"/>
        <property type="gene ID" value="VDA_000892"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2084">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008679">
        <property type="term" value="F:2-hydroxy-3-oxopropionate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016054">
        <property type="term" value="P:organic acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002204">
        <property type="entry name" value="3-OH-isobutyrate_DH-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015815">
        <property type="entry name" value="HIBADH-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029154">
        <property type="entry name" value="NADP-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14833">
        <property type="entry name" value="NAD_binding_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000103">
        <property type="entry name" value="HIBADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00895">
        <property type="entry name" value="3_HYDROXYISOBUT_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD_binding_2" evidence="3">
        <location>
            <begin position="4"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="NAD_binding_11" evidence="4">
        <location>
            <begin position="167"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000103-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF14833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="289" mass="30957" checksum="64B029EB0DD734D2" modified="2010-01-19" version="1">MHKKVAFIGLGTMGYPMAAHLQKAGYQVTVYNRTHEKAINWVKEYGGECALTPAVAAKGAEIIFTCVGNDNDVREVYYGDNGILSHAKPGAILVDNTTASAQLAQELYNAAKEVNCHFLDAPVSGGEAGAINGCLTVMVGGDKNVFEQAKDTIAAFAKAVTLMGDSGAGQTTKMANQICIAGILQGLSEAITLAKASGLNIEQMAEVLKHGAAGSWQLENRASTMAADQFNFGFAIDWMRKDLAICFEAADKLGVDLPMTHQVDKEYEKLQQQGLNRCDTSVLIKQFEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3B1</accession>
    <name>D0Z3B1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF1983 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000912</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305702.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000912"/>
    <dbReference type="EnsemblBacteria" id="EEZ39892">
        <property type="protein sequence ID" value="EEZ39892"/>
        <property type="gene ID" value="VDA_000912"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4733">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1485735at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015406">
        <property type="entry name" value="DUF1983"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09327">
        <property type="entry name" value="DUF1983"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1983" evidence="1">
        <location>
            <begin position="221"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="392" mass="41806" checksum="8E3106E8DEDFC54C" modified="2010-01-19" version="1">MVSPNRNKIAGFRGGRDPAALQENMELLTGQRGNGLDRAITVRELAQLGLINVTRNSQGSVVTKPVLPQAPDDKPISIPDAPVNFSGFGGFGAIMLEWKNPTFNGFAYAEIWRAVPNQDNSAPSIKQAVLIATTPATVFGDVVDPGSTFYYWCRFVNTNNVPGPYQGIDGVKVSTSTNIHDVVDDIGSQMKDSELIKSLSSDISNLSSSVTESQQAIKSINKDGSLAYQSLWSMKAQAGDIKAGIGFLAKSDGTSQVAVSASQFFVFDPNVAGGETQPLFAIDKGNVVIPKALIESATIQILTAQTIVADKVKSGISISSPQIHGGQITGGWAGFGIGGPYRGYHTAISKDGVIETNRLRFKSAQSGTRLEINGDRIEVWENGSIRVRMGRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3F3</accession>
    <name>D0Z3F3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000954</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305822.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000954"/>
    <dbReference type="EnsemblBacteria" id="EEZ39934">
        <property type="protein sequence ID" value="EEZ39934"/>
        <property type="gene ID" value="VDA_000954"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0697">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1425840at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="151"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="183"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="214"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="243"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="268"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="7"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="157"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="312" mass="34336" checksum="C14998C4BAC3A11F" modified="2010-01-19" version="1">MNNKHLPTLLFVSVCLIWGTTWLAMEVAVQTIPPIFATGLRFLVASPLLISLAIILKQPLFFPKGKRHWMLIVAVFYFSIPFTLMIYGEQYISSGLASIIFANMPIAVMLTSNLFLGLRLQKYQIFGLLIAVLSLIGILTIEMNLGGSDYLLGFMALGGAVAMHAIMYVFVEKFCKGTPVLTYNALPSFIASILLIMSSLFIEVPQIEQFSTDSIAAVIYLGLIASVGGIVAYFKLGQVSTPFTASLCFLFFPLIALSLSTWIAGNSISMLSVGLMFLLLGGIFITKADPYWFRKMSISKNPPHKPENIFSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3J3</accession>
    <name>D0Z3J3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RNA methyltransferase TrmH family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_000994</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305937.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000994"/>
    <dbReference type="EnsemblBacteria" id="EEZ39974">
        <property type="protein sequence ID" value="EEZ39974"/>
        <property type="gene ID" value="VDA_000994"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0566">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1422015at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004384">
        <property type="entry name" value="RNA_MeTrfase_TrmJ/LasT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42786">
        <property type="entry name" value="PTHR42786"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SpoU_methylase" evidence="4">
        <location>
            <begin position="10"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="182" mass="20111" checksum="20EA90B9614F2226" modified="2010-01-19" version="1">MNKQQNSYTIIGLTNPKSPTNVGAVMRAAGCYQADEVKYTGQRYDRAAKFSTDTKSMSQTIPLTGVDSLLDGLDDDIEIVCVELAEGATPLPLFQHPNKAIYIFGPEDGSIDQEIADRAQHVVYVPTVGCMNLAASVNVLLYDRLAKTSQIVQDNELIRRSRDNKNRLKVKESNTVDSSYSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3J4</accession>
    <name>D0Z3J4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CSD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000995</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305940.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39975">
        <property type="protein sequence ID" value="EEZ39975"/>
        <property type="gene ID" value="VDA_000995"/>
    </dbReference>
    <dbReference type="GeneID" id="57343289"/>
    <dbReference type="eggNOG" id="ENOG50320AV">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2041171at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002059">
        <property type="entry name" value="CSP_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00313">
        <property type="entry name" value="CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CSD" evidence="1">
        <location>
            <begin position="5"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="66" mass="7197" checksum="7048C0DFA7F7215D" modified="2010-01-19" version="1">MTSQTGIIRSFNPAEKKGLITCDLGGDISFDASQISCTSYPTMGSMVEFTLDESNSKLKAVKIRYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3T4</accession>
    <name>D0Z3T4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-acetylneuraminic acid outer membrane channel protein NanC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001085</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306185.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001085"/>
    <dbReference type="EnsemblBacteria" id="EEZ40065">
        <property type="protein sequence ID" value="EEZ40065"/>
        <property type="gene ID" value="VDA_001085"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1452">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1240612at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009331">
        <property type="entry name" value="Oligogalacturonate-sp_porin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38105">
        <property type="entry name" value="PTHR38105"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06178">
        <property type="entry name" value="KdgM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018822" evidence="1">
        <location>
            <begin position="23"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="242" mass="28585" checksum="42ADCA607369A2D0" modified="2010-01-19" version="1">MNTLTKVVIASTLVTAGGQALANDYKTTIEYRHQYVDGANKHSDRIKAFLDTGKGVGFELDARYNNDEKDKMFDSMSMNGSEFSAFYYKRLNPNTVGLVGMSLDFVPDGLVYVPYVRLNYKFDNNIRVQGRYKWKLWDYSMTGPSGDSYHSKIQEFDAWLGYNTQNWDFQYEFQIWKEMESNALPQFDNDDINYLHNFRLMYTYKTKDDTSWRPFIEIGNVSQSRYTDNRQTRYRMGIKYTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3V1</accession>
    <name>D0Z3V1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ATP synthase subunit delta</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">ATP synthase F(1) sector subunit delta</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">F-type ATPase subunit delta</fullName>
            <shortName evidence="7">F-ATPase subunit delta</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">atpH</name>
        <name evidence="8" type="ORF">VDA_001104</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.</text>
    </comment>
    <comment type="function">
        <text evidence="7">This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the ATPase delta chain family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306231.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001104"/>
    <dbReference type="EnsemblBacteria" id="EEZ40082">
        <property type="protein sequence ID" value="EEZ40082"/>
        <property type="gene ID" value="VDA_001104"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0712">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1937493at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01416">
        <property type="entry name" value="ATP_synth_delta_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026015">
        <property type="entry name" value="ATP_synth_OSCP/delta_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020781">
        <property type="entry name" value="ATPase_OSCP/d_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000711">
        <property type="entry name" value="ATPase_OSCP/dsu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11910">
        <property type="entry name" value="PTHR11910"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00213">
        <property type="entry name" value="OSCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00125">
        <property type="entry name" value="ATPASEDELTA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47928">
        <property type="entry name" value="SSF47928"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01145">
        <property type="entry name" value="ATP_synt_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00389">
        <property type="entry name" value="ATPASE_DELTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0139">CF(1)</keyword>
    <keyword evidence="2 7" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ40082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="182" mass="20346" checksum="E08E486C82F7029C" modified="2010-01-19" version="1">MSDPQTIAHPYAKAAFEFAKEQQALEQWAQMLTIVSDVVTQPVISEQLEDLEQLGNEQREQFVDMFLAICDGLLDEHVKNLIRVMAENSRLAVLSSVTELFLELKADYERTVQAHVVSADELTADQKVNLIAALEKKLDRHVELDCQIDKSLVGGMLIHAGELVIDGTLKTSMDRLASRLQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3W6</accession>
    <name>D0Z3W6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001119</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306272.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001119"/>
    <dbReference type="EnsemblBacteria" id="EEZ40097">
        <property type="protein sequence ID" value="EEZ40097"/>
        <property type="gene ID" value="VDA_001119"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2227">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="957193at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="256" mass="29496" checksum="4D15EB43812B626C" modified="2010-01-19" version="1">MANLKHQSVNLVDLYKKTAQGKYTTAEHYKDIPIHAMKGLHEYAVSIVTQYQNLDQQSAIDLGAGAGALSQRLADSGYQVTSLDLVPDNFRLSTQSFSFLPVDLNLPFCQCIQERYDLVTAVEIIEHLENPRAFFRECQALLQDNGILLLTTPNITSAFSVTESLIKDNFTYFDDGQYLNGGHISPISHWQIIKMAEENQLEIIHHSTFGKHHIHFREWPRFWLLYHINRLLRPDLKHRNGCINVYLMKKKQEIVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3Y9</accession>
    <name>D0Z3Y9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001142</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001142"/>
    <dbReference type="EnsemblBacteria" id="EEZ40120">
        <property type="protein sequence ID" value="EEZ40120"/>
        <property type="gene ID" value="VDA_001142"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2771">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="151"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="236" mass="26870" checksum="7B499670E9F49FFA" modified="2010-01-19" version="1">MKESVPPSLMHIFNQLPGCWGCKDLNSTFVYANKEYGNIIGVEHHLDCVGRTDFDMPSPTIECAEHFQEQDQQVIVSGQRLRILDIHPYSDGTWRAHLFTKMPWRNDDNKIIGTIFSGIELKDTALLEAGHWICRAAGLNPKEQASFNIDLHNSPIKLNTRESEVLFLLLYGKKPQYIAKVLNLSVKTIENYVLRLREKFNANTKGELLDLALDHGYGSHIPPSMLKQQLSVILKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3Z7</accession>
    <name>D0Z3Z7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">AsmA protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001150</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306351.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001150"/>
    <dbReference type="EnsemblBacteria" id="EEZ40128">
        <property type="protein sequence ID" value="EEZ40128"/>
        <property type="gene ID" value="VDA_001150"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2982">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="269286at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007844">
        <property type="entry name" value="AsmA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05170">
        <property type="entry name" value="AsmA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="domain" description="AsmA" evidence="3">
        <location>
            <begin position="25"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="AsmA" evidence="3">
        <location>
            <begin position="828"/>
            <end position="1210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="1312" mass="143094" checksum="490F4556F26DCCCB" modified="2010-01-19" version="1">MTKKDSVVAQEHSTTPEPSGKKPKMKKIAKWVGLSVLTPVAIGIGVLSYGVTLDLTPHKQKISQWLTKNLARETKIEGDIALTLSFSPEIDINKLTIGNTEAMKWQPMLSSGHASAKVSLLPLLRNTLEIDYLKLDNTHVELNRDYQGKPNWVFNSSPKVTTSDDKTSKPLTLKITDTITAKDVSVSYLDQQTGQYFSAAVEQLSLTKPDQWLLKAQGFVQGQSYDFSLTGDLESIINHQQGHLVAAGEFIGARLNIDADIQPWRTGVTHANIDLDWHDTAPIKSFLDLDIGPAAPLKITTKLSASHEGIGLTKLKIDSPVTQASGHLVFALAKKGQPLNYIDGKLDIPLIDLRPWLQPEQPQPMMMSYAAAPPQQSPLQQALDQWLVKTKTHLALKVGEIKGLGTPVHSIALTVDGKQGKLTAPMQANIADVAFTGSANIDATTGLSKVAISLGAKDSQLGEMAGWISGIPNATGHVNLAELNVDTQGTKLQEWIDNSKLALTIDKAQLDWGAKADFAINSAKLTAGMNIPFSSHISGQMMGIPAKIEASAGSLSDIINQRDWQTDFQFISPAITLKAKGQLVGTQWQQGSWFDLDIDSKDAGKLSPWLGTKSTIHGPIQLKGKLTYKQDWVTLEASNINLLRSQGNIDLKWKPTGDMFVGLNSHFSRLDLSQLSQFIDGDRLPHVEQTVPTQGVNLDVPILAHGLVVKNADVSVNVDTMKWSKQQLHQLSFTGKMRNGIMPAAPFSANYLGSQYRGNIALKINQNKIASTLNLSVNKPNVGAILNQFNISNDFDFSLRRAQLHLALSGRSMIEFMEQANINAQLIGGHLGVKQQYTGKAFNIELDKGQFITGPNTETSLSLVGQAAQDPVNITLNSVSLKQANDGRKTIPLSLIANIGDIKLNARSQVKMPLDMRKLNLAVEATTPNLNRFNKFTGVELPPYGPIKVAGQLTSDPNGYHLNNMLLQVGSSELTGKGDLLLTHKPQRIRPRINLDLSAPFIQLNDFKVKGWHAWQQESSASKAPQASKPVALMSPDGLKKFDATFSLNVGEVRSGNDWLGAGELDWTLNNGLLTVNPLHIKLPGGEIDLSGSVKAVGDKFDIGLKGKVENFDYGILARRIDPKTTMHGLLSTEFNLHSLANTPESLMNNASGFLGFAVWPKAFQANVVDLWAVSLADAVLPSLTKHDPSVINCVAGGFNINHGTMKQRDLLLDTTRIQVHGTFDANFKQRDFSMYLSPKAKRAQIFGLQTPVEVTGNFNDFNLNIPLSAILETSVRFTTSPVIAPLSWLFEKPIAPNASSECQRIWQGLPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3Z9</accession>
    <name>D0Z3Z9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001152</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001152"/>
    <dbReference type="EnsemblBacteria" id="EEZ40130">
        <property type="protein sequence ID" value="EEZ40130"/>
        <property type="gene ID" value="VDA_001152"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3637">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025079">
        <property type="entry name" value="DUF3943"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027385">
        <property type="entry name" value="OMP_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13084">
        <property type="entry name" value="DUF3943"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13505">
        <property type="entry name" value="OMP_b-brl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019979" evidence="1">
        <location>
            <begin position="26"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3943" evidence="2">
        <location>
            <begin position="110"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="OMP_b-brl" evidence="3">
        <location>
            <begin position="296"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="443" mass="50379" checksum="07B4840F8805C038" modified="2010-01-19" version="1">MTKKYSSLALCICSTLAFSPSLSYASSTISNSQWENNSSLPYSASNPYEIALFSAHNGEDKARLWSQTQSIIGYGLGVAGFLALLPSDFTNWDKSDDRLLEKWYDNVTEGPVWDRDVWYINYIGHPYFGGVYYQVARKSGYRQWDSFLYSALMSTVYWEYGVEAFAEVPSIQDLVVTPVLGWVYGEWAFQQERHIRASGGKVLGSQTLGDTALFLLDPVDSIGRGINQLTGRNLVKAGTGYISYNQQQHRNGKTDNQIALNVSYQLNDPNQRSDRHYRERGYTQLTNDPVTYGIVGITAGASYLNLDPKWGLQNDWAPTMSLGLYFTKQFSSRLNYTRADLKSTTTQQTNTYESYNLDVQYYFNPHGQLRPYVSAGIGESLKDQDRDIKSFQYVGGAGLHYKFHPNWAFQLDWRHHYGTKYSTNDDLFTGQIVYRFGQGERGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z438</accession>
    <name>D0Z438_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_000294</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303967.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000294"/>
    <dbReference type="EnsemblBacteria" id="EEZ39276">
        <property type="protein sequence ID" value="EEZ39276"/>
        <property type="gene ID" value="VDA_000294"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4181">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1181903at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042953">
        <property type="term" value="P:lipoprotein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015854">
        <property type="entry name" value="ABC_transpr_LolD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24220:SF654">
        <property type="entry name" value="PTHR24220:SF654"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="7"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="43"/>
            <end position="50"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="226" mass="24436" checksum="43C9AD80CE1705D2" modified="2010-01-19" version="1">MSVSSVIKAHAITKRVITTSSSMTILQDISLEVEQGESIALVGVSGAGKSTLMTLLAGLDLPSSGTVELLGHNLTELNDEQRAALRSKSVGFVFQSFLLLPTLTAFENVTLPCLIQDIPVDIERAKQLLAQVGLDKRSDHLPSQLSGGEQQRVALARAFMSQPKILFADEPTGNLDQHTAAKVIELLFELNRSSGTTLILVTHDNQLAHRCDRVLTLDNGKLKETL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z451</accession>
    <name>D0Z451_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Urease accessory protein UreD</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ureD</name>
        <name evidence="5" type="ORF">VDA_000307</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the UreD family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303999.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000307"/>
    <dbReference type="EnsemblBacteria" id="EEZ39289">
        <property type="protein sequence ID" value="EEZ39289"/>
        <property type="gene ID" value="VDA_000307"/>
    </dbReference>
    <dbReference type="GeneID" id="57343311"/>
    <dbReference type="eggNOG" id="COG0829">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1764668at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01384">
        <property type="entry name" value="UreD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002669">
        <property type="entry name" value="UreD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33643">
        <property type="entry name" value="PTHR33643"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01774">
        <property type="entry name" value="UreD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0996">Nickel insertion</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="282" mass="32128" checksum="9E48C1914268B2C3" modified="2010-01-19" version="1">MPESSNSNLGWLAELFLRYEQRRGMTRLVERKQIGPLAVQRPFYPENGISHTYLLHPPGGVVGGDQIHINVEVGPDCHSLLTTPGATKFYRSTGVTATQKQTLIVKDNGILEWLPQENIFFPNSHCDLNTHVILTSAAKFIGWEIQCFGRPTLNEVFSSGQIRCSTRIELDNQLISLESLYLEQLDPDKQSAGMRQYPMIGTLYIYPYSEDLKIELQNTLSLYQQRCNEALEYGLTDIDGLIAIRLLGKHTEPMMGCFVEVWKRTRLHWFGVEPTVPRIWAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4D3</accession>
    <name>D0Z4D3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hypothetical oxidoreductase yqhD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000389</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the iron-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304230.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000389"/>
    <dbReference type="EnsemblBacteria" id="EEZ39371">
        <property type="protein sequence ID" value="EEZ39371"/>
        <property type="gene ID" value="VDA_000389"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1979">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="717704at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990362">
        <property type="term" value="F:butanol dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08187">
        <property type="entry name" value="BDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001670">
        <property type="entry name" value="ADH_Fe/GldA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018211">
        <property type="entry name" value="ADH_Fe_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044731">
        <property type="entry name" value="BDH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43633">
        <property type="entry name" value="PTHR43633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00465">
        <property type="entry name" value="Fe-ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00060">
        <property type="entry name" value="ADH_IRON_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe-ADH" evidence="3">
        <location>
            <begin position="9"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="382" mass="41662" checksum="C4D6BDD95C9C1A07" modified="2010-01-19" version="1">MNNFTFSSPSQIFFGKGQIEAISHAIPKEKKVLVIYGGGSIKQNGVYEQVSRALDGFQWGEFSGIEPNPQYDTLMQAVTVIREQGYDYLLAVGGGSVIDGTKFIAAAVHFTDEPWNLLSKKAPFHDPLPLGCVLTLPATGSETNSGAVISRGNDKLSFGSPSLKPQLAILDPTTTFSLSAKQTANGVVDAFVHVMEQYLTYPVDAKVQDRFAEGLLHTLIEEGPKALADPENYDVRANIMWAATQALNGIIGVGVPQDWTSHHIGHELTAHFGIDHGRTLSIVLPGVMQECRTEKSAKILQYGERIFGLTQGTEQERIDSAITHTISFFQQMGMPTSLAEEGLDHHAIDIVLQGMQKHGMTTEGEHQTVTLSRSRAILEFVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4I3</accession>
    <name>D0Z4I3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Metal-dependent hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000441</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304375.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000441"/>
    <dbReference type="EnsemblBacteria" id="EEZ39421">
        <property type="protein sequence ID" value="EEZ39421"/>
        <property type="gene ID" value="VDA_000441"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3568">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1387978at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endo/exonuclease/phosphatase" evidence="1">
        <location>
            <begin position="29"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="296" mass="34878" checksum="175EE482E6F313AD" modified="2010-01-19" version="1">MRNIKPLKLILAYIALSPNVTTAEELRIMSWNMQWLNHHASSPVLRDTDDFSQIRSIIEQVDPDILAFQEVGSLKAMTMVLPLKQYDILLSSRADHPRYTFPNTNQFTGFAIRKNIRYRELPDFTKINLNKKGLRYGKNLKIWWQDQQIHLLNIHLKAGCKQSKRSKACRQLKKQLKLLSLWLKTRIENNHSYILLGDFNYPLYTSLNNKKEKQHNHWFFKQLGIPTTALKQHKTSFSCQIKIHHKKSRLITYTQPIDHVISDKINISKLETYQYTNKEMSSNQLSDHCPLYFSIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4L5</accession>
    <name>D0Z4L5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GntR-family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000473</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000473"/>
    <dbReference type="EnsemblBacteria" id="EEZ39453">
        <property type="protein sequence ID" value="EEZ39453"/>
        <property type="gene ID" value="VDA_000473"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2188">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028978">
        <property type="entry name" value="Chorismate_lyase_/UTRA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011663">
        <property type="entry name" value="UTRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07702">
        <property type="entry name" value="UTRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00035">
        <property type="entry name" value="HTHGNTR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00866">
        <property type="entry name" value="UTRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64288">
        <property type="entry name" value="SSF64288"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="domain" description="HTH gntR-type" evidence="2">
        <location>
            <begin position="80"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="306" mass="34160" checksum="B53157E1F35D795D" modified="2010-01-19" version="1">MNKCDDISMSHLSLSYKLNFVHDKSSLSPVKLFYDSIVIIATLFVTIVASISLIIIIKAHAMELSLIRFIKNNLNAELSKPLYIQLKDSIEIAINNKMLVHGSVLLSERKLAQELAVSRVTIVKALAELQIEGTVVKQHGKGTVIQLPVQYDLAGGGFSSQLKSKGKVTNRWIIRTPVCADDFLARKLGVIVGDVISHIKRVRLIDNVPVSIETTYIPQCFMPRPDLLDGSLYEYWETMGIVPKQQDYSLSIYVPTADEALLLDIPKGSPLMKVELSSKDQNGVVLEYGTAICRSDFYRFNFKTTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4N0</accession>
    <name>D0Z4N0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cytochrome-c oxidase</fullName>
            <ecNumber evidence="5">7.1.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">VDA_000488</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>4 Fe(II)-[cytochrome c] + 8 H(+)(in) + O2 = 4 Fe(III)-[cytochrome c] + 4 H(+)(out) + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:11436"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="7.1.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
        <text evidence="10">Binds 1 copper ion per subunit, denoted as copper B.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
        <text evidence="10">Binds 2 heme groups per subunit, denoted as high- and low-spin.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Energy metabolism; oxidative phosphorylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the heme-copper respiratory oxidase family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.9" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304504.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000488"/>
    <dbReference type="EnsemblBacteria" id="EEZ39468">
        <property type="protein sequence ID" value="EEZ39468"/>
        <property type="gene ID" value="VDA_000488"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3278">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="665754at2"/>
    <dbReference type="UniPathway" id="UPA00705"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045278">
        <property type="term" value="C:plasma membrane respiratory chain complex IV"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004129">
        <property type="term" value="F:cytochrome-c oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006119">
        <property type="term" value="P:oxidative phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.210.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023616">
        <property type="entry name" value="Cyt_c_oxase-like_su1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036927">
        <property type="entry name" value="Cyt_c_oxase-like_su1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000883">
        <property type="entry name" value="Cyt_C_Oxase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023615">
        <property type="entry name" value="Cyt_c_Oxase_su1_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004677">
        <property type="entry name" value="Cyt_c_oxidase_cbb3_su1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10422">
        <property type="entry name" value="PTHR10422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10422:SF29">
        <property type="entry name" value="PTHR10422:SF29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00115">
        <property type="entry name" value="COX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81442">
        <property type="entry name" value="SSF81442"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00780">
        <property type="entry name" value="ccoN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50855">
        <property type="entry name" value="COX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00077">
        <property type="entry name" value="COX1_CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0249">Electron transport</keyword>
    <keyword evidence="10 11" id="KW-0349">Heme</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="8 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="6 11 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="90"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="125"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="154"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="200"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="234"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="264"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="302"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="339"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="383"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="428"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="domain" description="COX1" evidence="13">
        <location>
            <begin position="1"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
            <label>B</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="254"/>
        </location>
        <ligand>
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
            <label>B</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="255"/>
        </location>
        <ligand>
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
            <label>B</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR604677-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEZ39468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="470" mass="54503" checksum="1A48DE3D599632A7" modified="2010-01-19" version="1">MDTTHYDTKVVRYFIISSLAWGVIAMLIGVLLAAQLYWPALNFNSEYIQFGRLRPLHTNGVIFGFTVNLLMATSLYIVQKTCRVPLFNHSLSWFVFWGWQLILVLALITLPLGFTTSKEYAELEWPIDILIAVVWVMYAILFFMTIARRQEPHIFVANWFFGAFIIVIAMIFVVNNLELPVSMWKSYSVYAGAQDAIVQWWWGHNAVGFLLTAGVIGMNYYFIPKVSERPIYSYRLSVVHFWGLVGFYTWAGTHHLIYSSVPDWVQNVGIIMSLILWLPSWSGAFNSFMTLLSNKEKLKHDYIMWFFFSAIAYYCLATFEGPLLAIRWFNMIAHNTDWVIGHVHSGALGWVGMSAIAVFYYFIPRLWQRDYIWSNRLVKWHFWLAHLGIALYAIALWIAGIGEGYMWLKQEPNGALSYSFVEVMNFSKLWLLMRFIGGALFVFGLLLMVYNLYRTLTGPKSRPVYDSQEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4P7</accession>
    <name>D0Z4P7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glycine dehydrogenase (decarboxylating)</fullName>
            <ecNumber evidence="7">1.4.4.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Glycine cleavage system P-protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Glycine decarboxylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Glycine dehydrogenase (aminomethyl-transferring)</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">gcvP</name>
        <name evidence="9" type="ORF">VDA_000505</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>(R)-N(6)-lipoyl-L-lysyl-[glycine-cleavage complex H protein] + glycine + H(+) = (R)-N(6)-(S(8)-aminomethyldihydrolipoyl)-L-lysyl-[glycine-cleavage complex H protein] + CO2</text>
            <dbReference type="Rhea" id="RHEA:24304"/>
            <dbReference type="Rhea" id="RHEA-COMP:10494"/>
            <dbReference type="Rhea" id="RHEA-COMP:10495"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83143"/>
            <dbReference type="EC" id="1.4.4.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7 8">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4 7">The glycine cleavage system is composed of four proteins: P, T, L and H.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the GcvP family.</text>
    </comment>
    <dbReference type="EC" id="1.4.4.2" evidence="7"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304561.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000505"/>
    <dbReference type="EnsemblBacteria" id="EEZ39485">
        <property type="protein sequence ID" value="EEZ39485"/>
        <property type="gene ID" value="VDA_000505"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0403">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1003">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="70707at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004375">
        <property type="term" value="F:glycine dehydrogenase (decarboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019464">
        <property type="term" value="P:glycine decarboxylation via glycine cleavage system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00613">
        <property type="entry name" value="GDC-P"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00711">
        <property type="entry name" value="GcvP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003437">
        <property type="entry name" value="GcvP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020581">
        <property type="entry name" value="GDC_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11773">
        <property type="entry name" value="PTHR11773"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02347">
        <property type="entry name" value="GDC-P"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00461">
        <property type="entry name" value="gcvP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7 8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="7 8">
        <location>
            <position position="705"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00033655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR603437-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ39485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="957" mass="105665" checksum="46CC7F9B35121CC5" modified="2010-01-19" version="1">MSLLTTFTDHNTFVNRHNGPTLEQQQTMLAAIGVDNLDQLIDQTVPANIRLPQPLQLPKAINEEMLLQQLKHIAQKNIINKSYIGQGYYNTYTPSVILRNILENPGWYTAYTPYQPEISQGRLESLLNYQQMVMDLTGMDLANASLLDESTAAAEAMMLCKRASKNKSSAFFVSNEVHPQTLDVIRTRAKFVGIEVITGNLEQLDDNEVFGALLQYPGSSGEIHDLTAIIANAHAKKTLVAVASDLLALTLLTPPGEMGADVVVGSAQRFGVPMGFGGPHAGFMATQDKHKRTMPGRVIGVSKDSQGNQALRMAMQTREQHIRREKATSNICTAQALLANMAAFYAMYHGPEGLKNIARRVHHFTAILAAGIRDVGFERKNYYFFDTLTVHTLNHTEVIYQKAQQQGLNLRLVDSETLAISLDETTTLNDVEQLLQLFDGNTTQLSFYSEQVEQNEFSAIPPSCLRHSTYLTHPVFNSYHSETQMMRYMKHLENKDYSLTHGMIPLGSCTMKLNAATEMIPITWPEFGQLHPFAPQEQSQGYQELTQSLAAMLCEITGYDAFSLQPNSGAQGEYAGLVAIQRYHEANGDGHRNVCLIPSSAHGTNPASAAMVSMKVVVVKCDHLGNIDIVDLKDKIEQHRDNLSCIMITYPSTHGVYEEGVREVCELVHQAGGQVYLDGANMNAQVGLTSPGYIGSDVSHLNLHKTFCIPHGGGGPGMGPIGIKSHLAPFVPGHIITASSHNDPQYAVSGAPLGSASILPISYAYIAMMGEAGLTEATKLAILNANYVKAKLSPYYSILYQGKQGHIAHECIIDIRPIKESSGISEEDIAKRLMDYGFHAPTMSFPVAGTLMVEPTESEDLAELDRFCDAMIAIRHEIEQVENGTWPLQDNPLVNAPHTQFDLMAEQWTHPYSRELACFPAKHSRYSKYWPTVNRVDNVFGDRNLICSCPSIESYEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4Q5</accession>
    <name>D0Z4Q5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribose ABC transport system ATP-binding protein RbsA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_000513</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304585.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000513"/>
    <dbReference type="EnsemblBacteria" id="EEZ39493">
        <property type="protein sequence ID" value="EEZ39493"/>
        <property type="gene ID" value="VDA_000513"/>
    </dbReference>
    <dbReference type="GeneID" id="57342796"/>
    <dbReference type="eggNOG" id="COG1129">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="551294at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="6"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="501" mass="54781" checksum="67E3ADD73181D21D" modified="2010-01-19" version="1">MTQPILALEGIEKAFPGVKALDNACLNVYPGRVMALMGENGAGKSTLMKVLTGIYSKDAGEVRYQGAPVHFHGPRHSQEAGISIIHQELNLIPELTIAENIFLGREKTNAFGGIKWAEMYREADALLKRLNVKHSSRQLLGELSLGEQQMVEIAKALSFKSQVIIMDEPTDALTDTETESLFNVINELRSEGCGIVYISHRLKEIFEICDDITVLRDGKFIGECRVADTDEDGLIEMMVGRRLDEQYPRIAVKHGTTCLEVKNLTGSGINDVSFTLDRGEILGISGLMGAGRTELMKVIYGALTRESGDVILDGKIINPISPQDGLANGIAYISEDRKGDGLILGLSVKENMSLCALEQLSNGIKIDQQQEVIAVEDFIRLFNIKTPTRDQIIGNLSGGNQQKVAIAKGLMTKPKVLILDEPTRGVDVGAKKEIYQLINQFKADGMSIILVSSEMPEVLGMSDRILVMHEGRISGEFTPEEANQEKLLACAVGKRIDEVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4Z1</accession>
    <name>D0Z4Z1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000224</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306653.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000224"/>
    <dbReference type="EnsemblBacteria" id="EEZ39208">
        <property type="protein sequence ID" value="EEZ39208"/>
        <property type="gene ID" value="VDA_000224"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5599">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="901171at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006470">
        <property type="term" value="P:protein dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000242">
        <property type="entry name" value="PTP_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003595">
        <property type="entry name" value="Tyr_Pase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00102">
        <property type="entry name" value="Y_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00700">
        <property type="entry name" value="PRTYPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00194">
        <property type="entry name" value="PTPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00404">
        <property type="entry name" value="PTPc_motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="SSF52799"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50055">
        <property type="entry name" value="TYR_PHOSPHATASE_PTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="2">
        <location>
            <begin position="340"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="domain" description="TYR_PHOSPHATASE_2" evidence="3">
        <location>
            <begin position="487"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="572" mass="61797" checksum="CB2ECD0BD8D4A2F1" modified="2010-01-19" version="1">MPVNNQIQNNLNIQTLTSYIDKASASQSAANANVSYGAMGNAVINTGVSKALNQAAKELIADVKNITLTNDDVKNLYQAQPKAGFALGSQDGVIFVKQIKGELTLEAADILLGAAKRDSAESELANPSSSPTRNTRPNTHPPVSQHGKSEERIYENLQFKVRPQSPVHSPRTNTPPPVPAHAGRSSSPSPAHGSRPSSPVHAVGANSSLDTTKLENTFSAYSDVDIMQKRPSADHKFVAVWPSSKGDGSFGIHLPGARPKRATTLEQAQSIVNNHLQQQSQVQQNHHARNVLASGAQDHREELAQFEQKLGQYKDNISKKNHPEYYHKDPVGTSKENKVDRFGDIGTMLHSKVGYNLNANRITVAGQDVAIATQYPKDSQIEDQLRLLVDNRTPSLTVLTEASQMANPAKGMTDYFSRNLGFNSGLTTQSELTSRDMVVGRNTDGSDLKANVFNLTINIPGEAPFTVPVLHVTNWIDKTAIDAESSNNIATMINGIESDGGAPVVHCRAGVGRTGQIVAAIAMQKVPNSVSAEEVINDMRYSRNDYMGQTDEQRAVIADLARQQGRPVLALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z549</accession>
    <name>D0Z549_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Type II/IV secretion system ATP hydrolase TadA/VirB11/CpaF TadA subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000099</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GSP E family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306844.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000099"/>
    <dbReference type="EnsemblBacteria" id="EEZ39083">
        <property type="protein sequence ID" value="EEZ39083"/>
        <property type="gene ID" value="VDA_000099"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4962">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="473670at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001482">
        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00437">
        <property type="entry name" value="T2SSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="2">
        <location>
            <begin position="195"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="426" mass="46837" checksum="2A0F40A4FCDB98A1" modified="2010-01-19" version="1">MEQNKSIYIAIREQIFEALEADAVKTLTRKQLSKQLANAIDLIIDRHGWSVAGVIREEYVKSLVDELQGLGPLQPLMDDESISDIMINGCDHVFIEKNGVVEQANISFIDENQLIHIAKRIASRVGRRVDESSPTCDARLPDGSRVNIVIPPIAIDGTAISIRKFKKQTIGLDKLTEFGAMSPEMAQVLMIAARCRLNILISGGTGSGKTTLLNALSQFISEKERIVTIEDAAELRLLQPHVVRLETRTSGIEGTGAITQRDLVINSLRMRPDRIVIGECRGGEAFEMLQAMNTGHDGSMSTLHANTPRDALARVESMVIMATNNLPLEAIRRTIVSAVDIVIQISRLHDGSRRIMSISEVVGLEGSNVVLEEIFKFQTISPDTSGRVRGNFITAGLIQRSVLVEKARFYGLDEQLKAAFNSGESV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z579</accession>
    <name>D0Z579_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000039</name>
        <name evidence="2" type="ORF">VDA_000129</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000005">
        <property type="protein sequence ID" value="EEZ39054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39054">
        <property type="protein sequence ID" value="EEZ39054"/>
        <property type="gene ID" value="VDA_000039"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39113">
        <property type="protein sequence ID" value="EEZ39113"/>
        <property type="gene ID" value="VDA_000129"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="39" mass="4474" checksum="0C03AA467F914882" modified="2010-01-19" version="1">MDVFGNQSAVWANLVKHCFFFTLKRPNAGVYQKREEGKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5A7</accession>
    <name>D0Z5A7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Outer membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000157</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005307008.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000157"/>
    <dbReference type="EnsemblBacteria" id="EEZ39141">
        <property type="protein sequence ID" value="EEZ39141"/>
        <property type="gene ID" value="VDA_000157"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1538">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1099555at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018881" evidence="2">
        <location>
            <begin position="25"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="423" mass="47757" checksum="0AB788A9307AA184" modified="2010-01-19" version="1">MTKLHLVKVGCTILIATFSFPSYAISIEQAWQKAKQSDPNYEKVKIDVRRSEVKVDAIRRSFQPSLSATISASWRESFSNTNGYGASLSQTIWDSSLWSDLDQANSNYIKTKLLLVQSRNELARRLLSSYLDVASAQSDLQLAQSKLEEDGKLLKIIEKRYLAGKVKSVDVEEIRATQVADKLSILSTRSDLEVKRTTLAALINQIPLSVNQIRIDSLIQPIMMADTQEQWLKLAKDSSPELLEAIQNIKASEFAKDSARGGYYPTVKGHVSYNNDDRRKNGEFNAGITLHMPIDLNGATQARVEEASLNILSAKQDLRKVEIDIQKRVIQQFTQVVINWNQVLMTNKLVISREKVLRNKEKLYDAGLLEISEVISAHNSLFIAKNDLQNNLYNYWRQHIDLLQTAGKLDDDAIALISRAFNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5G7</accession>
    <name>D0Z5G7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000074</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000006">
        <property type="protein sequence ID" value="EEZ39019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005307158.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000006.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39019">
        <property type="protein sequence ID" value="EEZ39019"/>
        <property type="gene ID" value="VDA_000074"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031P00">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1898506at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="198" mass="22778" checksum="6D0EABB9CBECD264" modified="2010-01-19" version="1">MQYALLESPNPENDYRFLVDANELKSLFDGLDKLIPSDAPDDEQSLPLTLVYGVYMPQPFFEFPKSEIKRNILKSVNHWLAYLKGNELFYCGLEDIELLDITVMKSCGHCPRPHASNDIAFAALMRIPQDIKLGNGKTQAKTVFLRWHNMDVLTNLINRDGLFSLIAPEKRIKGELDSNNWKTFIDYPRAARLAQKFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5K0</accession>
    <name>D0Z5K0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">IncF plasmid conjugative transfer protein TraD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000018</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000008">
        <property type="protein sequence ID" value="EEZ38992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000018"/>
    <dbReference type="EnsemblBacteria" id="EEZ38992">
        <property type="protein sequence ID" value="EEZ38992"/>
        <property type="gene ID" value="VDA_000018"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3505">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014128">
        <property type="entry name" value="T4SS_TraD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019476">
        <property type="entry name" value="T4SS_TraD_DNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10412">
        <property type="entry name" value="TrwB_AAD_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02759">
        <property type="entry name" value="TraD_Ftype"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="33"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="domain" description="TrwB_AAD_bind" evidence="3">
        <location>
            <begin position="181"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="625"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="636"/>
            <end position="703"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ38992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="709" mass="81660" checksum="9A39E2F65BCB2DE0" modified="2010-01-19" version="1">MLIKHKARPKSNTKAFTRGGQITFHNLRMYFQILAVIGSWSMVIAFIFTALFAYFLIDIDQLLALKYYFHAKYLSLPDTKIMVMYQGQEYPYTAEKLLSSERFNASVDDVFLDIQLAFIFSFFAVMIAFMKVTKYFEKKGEEQTQDYLIRGTEIATPQELERRLKKDKNTSPFKLDGLSLLPNNFEIRHLSFSGSTGTGKSVAIRKLLREIRARGDKAIIYDKGCTFVSRFYNEHKDYILNPFDERSVDWKIWYDAQEFSDFESLSTALIADSGHGDPFWIESARTLFTNTAYQMTQDGKPLTNERLLDYILKTPTSVLREFLKGTMASAITDEKADKIAISVKSILAAYIKSLRYLEGLDQQDKNGKRRKAFSVRDWVLDDNEKGFLFLTSNAQQHVSLRPLISMWLSTASTAILGLDESTTRRIWVIADELPSLHRLPDLASTLAEVRKHGGCYLVGFQSFAQFVKIYGRDAAEEMYDLLNTRFYFRNPSAPQAEKSSKDLGEQEIEISKEQYSYGANSVRDGISLGHQTITRPAVMTSEIMALDDLQCWYRTFGGYPITRINFKFDDMPSVAVPFIKRVYDSSDTMKRIDGELAHYQMGALLALPDEDKQVLLNIHKARHNNEQGDCDQSSYDNECEQMKETVKENNERMEKEQSEKEKSRNDDQDIEKQKMKEELELKRQMSADDQTEQAFKEMEETTISADLEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVN9</accession>
    <name>D0YVN9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Nitrogen regulatory protein P-II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001204</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the P(II) protein family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297633.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001204"/>
    <dbReference type="EnsemblBacteria" id="EEZ40182">
        <property type="protein sequence ID" value="EEZ40182"/>
        <property type="gene ID" value="VDA_001204"/>
    </dbReference>
    <dbReference type="GeneID" id="57339940"/>
    <dbReference type="eggNOG" id="COG0347">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2021322at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030234">
        <property type="term" value="F:enzyme regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006808">
        <property type="term" value="P:regulation of nitrogen utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002187">
        <property type="entry name" value="N-reg_PII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017918">
        <property type="entry name" value="N-reg_PII_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002332">
        <property type="entry name" value="N-reg_PII_urydylation_site"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30115">
        <property type="entry name" value="PTHR30115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00543">
        <property type="entry name" value="P-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039144">
        <property type="entry name" value="GlnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00340">
        <property type="entry name" value="PIIGLNB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00938">
        <property type="entry name" value="P-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="SSF54913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00638">
        <property type="entry name" value="PII_GLNB_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51343">
        <property type="entry name" value="PII_GLNB_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00496">
        <property type="entry name" value="PII_GLNB_UMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="O-UMP-tyrosine" evidence="2">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR039144-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR602187-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="112" mass="12347" checksum="AFFAE192CF8CF0A0" modified="2010-01-19" version="1">MKIINAIIKPFKLDDVREALSDVGVEGMTVTEVKGFGRQKGHTELYRGAEYQVDFLPKVKLEIATQADNLDAIVEAIAKAAQTGKIGDGKIFVYDLEHAVRIRTGEIDMEAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVY4</accession>
    <name>D0YVY4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">GTPase Era</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">era</name>
        <name evidence="12" type="ORF">VDA_001263</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 8 9">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6 8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001263"/>
    <dbReference type="EnsemblBacteria" id="EEZ40241">
        <property type="protein sequence ID" value="EEZ40241"/>
        <property type="gene ID" value="VDA_001263"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1159">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070181">
        <property type="term" value="F:small ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04163">
        <property type="entry name" value="Era"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00367">
        <property type="entry name" value="GTPase_Era"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030388">
        <property type="entry name" value="G_ERA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005662">
        <property type="entry name" value="GTP-bd_Era"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004044">
        <property type="entry name" value="KH_dom_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42698">
        <property type="entry name" value="PTHR42698"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07650">
        <property type="entry name" value="KH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="SSF54814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00436">
        <property type="entry name" value="era"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51713">
        <property type="entry name" value="G_ERA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50823">
        <property type="entry name" value="KH_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6 9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 6 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="4 6 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Era-type G" evidence="11">
        <location>
            <begin position="1"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="KH type-2" evidence="10">
        <location>
            <begin position="166"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="30"/>
            <end position="34"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="92"/>
            <end position="95"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ40241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="270" mass="31279" checksum="CA0707B1020763E2" modified="2010-01-19" version="1">MSITSRKPQTTRHRIMGVDTRDGYQAVYVDTPGLHIEEKRAINRLMNRAASSSLTDVELVLFLVDGTVWTQDDEMVLRKLEKAQLPTVLLVNKVDNVKEKYDLFPHMQEIASKMNFVDVVPVSAKHGTNIEVVEKIVRNHLPECDYYFPEEYVTDRSQRFMASEIIREKLMRFTGDELPYSVTVEIERFDYNPETDGFDINGLILVERTGQKKMVIGKAGQKIKVIGREARIDMEELFERKVYLELWVKVKSGWADDERALRSLGYIDDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVZ4</accession>
    <name>D0YVZ4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cell division protein FtsB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ftsB</name>
        <name evidence="4" type="ORF">VDA_001273</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of a complex composed of FtsB, FtsL and FtsQ.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell inner membrane</location>
            <topology evidence="3">Single-pass type II membrane protein</topology>
        </subcellularLocation>
        <text evidence="3">Localizes to the division septum.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FtsB family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001273"/>
    <dbReference type="EnsemblBacteria" id="EEZ40251">
        <property type="protein sequence ID" value="EEZ40251"/>
        <property type="gene ID" value="VDA_001273"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2919">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043093">
        <property type="term" value="P:FtsZ-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00599">
        <property type="entry name" value="FtsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023081">
        <property type="entry name" value="Cell_div_FtsB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007060">
        <property type="entry name" value="FtsL/DivIC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37485">
        <property type="entry name" value="PTHR37485"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04977">
        <property type="entry name" value="DivIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 4" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1 3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="topological domain" description="Cytoplasmic" evidence="3">
        <location>
            <begin position="1"/>
            <end position="3"/>
        </location>
    </feature>
    <feature type="topological domain" description="Periplasmic" evidence="3">
        <location>
            <begin position="3"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="4"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="70" mass="8097" checksum="B879AEABE057A532" modified="2010-01-19" version="1">MDEYRSVQNNIQIQERANAELELRNQQMYAEINDLHGGNEAVEERARSDLGLIKPNETFFRIVGDDNDDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW40</accession>
    <name>D0YW40_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 11">Chaperone protein ClpB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">clpB</name>
        <name evidence="13" type="ORF">VDA_001325</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homohexamer. The oligomerization is ATP-dependent.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Homohexamer; The oligomerization is ATP-dependent.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the ClpA/ClpB family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297862.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001325"/>
    <dbReference type="EnsemblBacteria" id="EEZ40300">
        <property type="protein sequence ID" value="EEZ40300"/>
        <property type="gene ID" value="VDA_001325"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0542">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="44062at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017730">
        <property type="entry name" value="Chaperonin_ClpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036628">
        <property type="entry name" value="Clp_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004176">
        <property type="entry name" value="Clp_R_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018368">
        <property type="entry name" value="ClpA/B_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028299">
        <property type="entry name" value="ClpA/B_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041546">
        <property type="entry name" value="ClpA/ClpB_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17871">
        <property type="entry name" value="AAA_lid_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02861">
        <property type="entry name" value="Clp_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81923">
        <property type="entry name" value="SSF81923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03346">
        <property type="entry name" value="chaperone_ClpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51903">
        <property type="entry name" value="CLP_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00870">
        <property type="entry name" value="CLPAB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00871">
        <property type="entry name" value="CLPAB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 10" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6 11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0677">Repeat</keyword>
    <keyword evidence="11" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="Clp R" evidence="12">
        <location>
            <begin position="3"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="412"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00026057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ40300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="857" mass="95655" checksum="2441E6053191537D" modified="2010-01-19" version="1">MRLDRFTSKFQTAISDAQSLALGRDHQYIEPAHLMVALLNQDGSTIRPLLTMLGVDITQLRSRLAEMLDRMPKVTGIGGEVQLSRDLGALLNMCDKLAQKRQDKFISSELFILAAVEDKGPLGQLLKEFHLTANTVEQAIDKVRGGQKVDDANAEENRQALEKYTVDLTARAEQGKLDPVIGRDEEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLALRIVNGEVPEGLRNKRVLSLDMGSLIAGAKFRGEFEERLKAVLNELSQEDGSVILFIDEIHTMVGAGKGEGSMDAGNMLKPALARGELHCVGATTLDEYRQYVEKDPALERRFQKVLVEEPSVEDTIAILRGLKERYELHHHVEITDPAIVAAATLSHRYISDRQLPDKAIDLIDEAASSIRMQIDSKPESLDRLERRIIQLKIEQQALEKESDEASQKRLSDLLEELDLKEREYAELEEVWNAEKAALSGTQHIKAELEQARTDVEIARRAGDLNRMSELQYGRIPELEKQLDLAAQAEMQEMTLLKNKVTDTEIADVLSKATGIPVAKMLEGERDKLLRMEEELHRRVIGQNEAVEAVANAIRRSRAGLADPNRPIGSFLFLGPTGVGKTELCKSLANFLFDSEDAMVRIDMSEFMEKHSVSRLVGAPPGYVGYEEGGYLTEAVRRRPYSVVLLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTVIIMTSNLGSDRIQEHFGSLDYEGLKALVMDVVGQHFRPEFINRVDETVVFHPLGQDNIKHIANIQLARLQKRLAEKDYRLDVDESALDLIAEAGFDPVYGARPLKRAIQQYIENALAQDILSGKLLPGKVIVVSAEDGQIVAKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWL9</accession>
    <name>D0YWL9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Tyrosine-protein kinase wzc</fullName>
            <ecNumber evidence="9">2.7.10.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_001510</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.10.2" evidence="9"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001510"/>
    <dbReference type="EnsemblBacteria" id="EEZ40484">
        <property type="protein sequence ID" value="EEZ40484"/>
        <property type="gene ID" value="VDA_001510"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0489">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3206">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004715">
        <property type="term" value="F:non-membrane spanning protein tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045226">
        <property type="term" value="P:extracellular polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025669">
        <property type="entry name" value="AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005702">
        <property type="entry name" value="EPS_synthesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032807">
        <property type="entry name" value="GNVR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13614">
        <property type="entry name" value="AAA_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13807">
        <property type="entry name" value="GNVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01007">
        <property type="entry name" value="eps_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0829">Tyrosine-protein kinase</keyword>
    <feature type="domain" description="GNVR" evidence="8">
        <location>
            <begin position="301"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="domain" description="AAA_31" evidence="7">
        <location>
            <begin position="470"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="189"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ40484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="656" mass="72170" checksum="CD97743E97A1B345" modified="2010-01-19" version="1">MSAMLGGEMSEMFSSDSTATTEIEIIKSRMVLGKTVDKLNLTTVVTPDYMPVIGAGLARLQGESIAAHISRFIVPDYVEPKSFTLTVDDAKQGTYTLTDSEGKEVLKGKVGELAEQGDYRLFVTDLNAQNGDSFTVSKISRLDAIQNLQRNLAVSERGKQTGILQLSLTGPNKADITAILNDISQNYFLQNVERNSAEAENSLAFLKQHLPDIKSQLMAAEDKLNRYRQANESVDLNLEAKAALDTMVGVEAQLNELTFKESDISQRFTKEHPAYISLLDKRKTLLAEKARLSKRVEKLPKTQREILRLMRDVEVNQQIYVQLLNKVQELSIVKASTVGNVRILDKAQAASIAVKPKKSLIVVLATLLGGMLAVGIALLRAAFHKGVENPDEIEAIGLPVYASIPMSDWQSELEKKQKSKKQLTVQDTLLAVSNPADLSVEALRSLRTSLHFAMMEAKNNILMISGPSPGIGKSFVSANMAAVIAKAGQRVLVIDADMRKGRMERQMSVSHKPGLSDFLCGQKSINEIIKQPGVENLDYIGRGDVPPNPSELLMHPRMKELLDWASANYDMVVVDTPPILAVTDAAIVGAHAGTTLLVGRFGQNAIKEIEVTKQRFEQNGIEIKGFILNAVVRKASSHYGQYGYGYYNYAYESDKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWP2</accession>
    <name>D0YWP2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Metallo-beta-lactamase family protein RNA-specific</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001528</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001528"/>
    <dbReference type="EnsemblBacteria" id="EEZ40502">
        <property type="protein sequence ID" value="EEZ40502"/>
        <property type="gene ID" value="VDA_001528"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1236">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022712">
        <property type="entry name" value="Beta_Casp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011108">
        <property type="entry name" value="RMMBL"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10996">
        <property type="entry name" value="Beta-Casp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07521">
        <property type="entry name" value="RMMBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01027">
        <property type="entry name" value="Beta-Casp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="16"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-Casp" evidence="2">
        <location>
            <begin position="242"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="475" mass="52611" checksum="4EF3C8BB689FAFA6" modified="2010-01-19" version="1">MDKIDIIHHGAKDGVTGSCHQLQIEQDGFTSSLLIDCGLFQGRESRPNLDIEFDISTVEALLITHCHIDHIGRIPWLLAKGFTGPIFTTEASAALLPLMLEDSLKLQLGLNKKQCQKFIERIEKQIKPVPYHCWIQQRLASFDSVSIRFSPAGHILGSAFIEIKLPNRQVVVFSGDLGPTNTPLLVDPQSPYQADILVLESTYGYKPTHGVKERALHLFDIIHRSLLDGGVILIPAFSVGRTQELLFDIENIIADTIYRCGLKEPIPINWQFLPVILDSPLAQKITDQYQQFQHLWAKEAKDKVYHGRHPLSFSQCITIEDHSDHLALINRLQKSGEPAIVVAASGMCTGGRIMNYLKALLPDSRTDVIFAGYQAEGTLGRELLDGALEVSIDKKSVEVNACIHQMSGYSAHAAQQDLLAFVDGIEHKPKRIHVIHGEEAAQRALADKLMTLYPEIEVVCGVDMGGDSGKEGKEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWT7</accession>
    <name>D0YWT7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Exodeoxyribonuclease III</fullName>
            <ecNumber evidence="4">3.1.11.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001482</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA repair enzymes AP/ExoA family.</text>
    </comment>
    <dbReference type="EC" id="3.1.11.2" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298133.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001482"/>
    <dbReference type="EnsemblBacteria" id="EEZ40456">
        <property type="protein sequence ID" value="EEZ40456"/>
        <property type="gene ID" value="VDA_001482"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0708">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1893707at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008853">
        <property type="term" value="F:exodeoxyribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09086">
        <property type="entry name" value="ExoIII-like_AP-endo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004808">
        <property type="entry name" value="AP_endonuc_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020847">
        <property type="entry name" value="AP_endonuclease_F1_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020848">
        <property type="entry name" value="AP_endonuclease_F1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037493">
        <property type="entry name" value="ExoIII-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43250">
        <property type="entry name" value="PTHR43250"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00633">
        <property type="entry name" value="xth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00726">
        <property type="entry name" value="AP_NUCLEASE_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00727">
        <property type="entry name" value="AP_NUCLEASE_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51435">
        <property type="entry name" value="AP_NUCLEASE_F1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endo/exonuclease/phosphatase" evidence="3">
        <location>
            <begin position="5"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="268" mass="30962" checksum="8C9EF42E9ABEE865" modified="2010-01-19" version="1">MKVISFNINGLRARLHQLQALIEKHQPDVIGLQEIKVHDEAFPLADVEAMGYKVYHHGQKAHYGVALLCKQEPIEVKKGFPTDDDDAQRRMIMATFEQENGKKITIMNGYFPQGDNINHETKFPAKEKFYADLMTYLNTYHNNDEELIVMGDINISPIDLDIGIGDNNAKRWLKTGKCSFQPIERQWLKTLLDWGFIDTFRQLHPTVDDQYSWFDYRSKGFDDNRGLRIDVILATPSLAERCIESGIDYELRGIEKPSDHAPIWSTFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWV5</accession>
    <name>D0YWV5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Bifunctional protein FolD</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="10">Methylenetetrahydrofolate dehydrogenase</fullName>
                <ecNumber evidence="10">1.5.1.5</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="10">Methenyltetrahydrofolate cyclohydrolase</fullName>
                <ecNumber evidence="10">3.5.4.9</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="10" type="primary">folD</name>
        <name evidence="13" type="ORF">VDA_001547</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NADP(+) = 5,10-methenyltetrahydrofolate + NADPH</text>
            <dbReference type="Rhea" id="RHEA:22812"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:57455"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.5.1.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>5,10-methenyltetrahydrofolate + H2O = (6S)-10-formyltetrahydrofolate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
            <dbReference type="ChEBI" id="CHEBI:57455"/>
            <dbReference type="EC" id="3.5.4.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="10">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.5" evidence="10"/>
    <dbReference type="EC" id="3.5.4.9" evidence="10"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298253.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001547"/>
    <dbReference type="EnsemblBacteria" id="EEZ40521">
        <property type="protein sequence ID" value="EEZ40521"/>
        <property type="gene ID" value="VDA_001547"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0190">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1449514at2"/>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004477">
        <property type="term" value="F:methenyltetrahydrofolate cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004488">
        <property type="term" value="F:methylenetetrahydrofolate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006164">
        <property type="term" value="P:purine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01080">
        <property type="entry name" value="NAD_bind_m-THF_DH_Cyclohyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01576">
        <property type="entry name" value="THF_DHG_CYH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000672">
        <property type="entry name" value="THF_DH/CycHdrlase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020630">
        <property type="entry name" value="THF_DH/CycHdrlase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020867">
        <property type="entry name" value="THF_DH/CycHdrlase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020631">
        <property type="entry name" value="THF_DH/CycHdrlase_NAD-bd_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00763">
        <property type="entry name" value="THF_DHG_CYH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02882">
        <property type="entry name" value="THF_DHG_CYH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00085">
        <property type="entry name" value="THFDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00766">
        <property type="entry name" value="THF_DHG_CYH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00767">
        <property type="entry name" value="THF_DHG_CYH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 10" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="4 10 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 10" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="9 10" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="5 10" id="KW-0521">NADP</keyword>
    <keyword evidence="1 10" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="6 10 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 10" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="THF_DHG_CYH" evidence="11">
        <location>
            <begin position="6"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="THF_DHG_CYH_C" evidence="12">
        <location>
            <begin position="124"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="166"/>
            <end position="168"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ40521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="286" mass="30811" checksum="E9EC2476543FABDA" modified="2010-01-19" version="1">MTAQIIDGKLISQTVRQEVAARVAARTQAGLRAPGLAVILVGQDPASQVYVNSKRKACEEVGFVSKSFDLPITTTESELLNLIAELNNDPIIDGILVQLPLPAGIDTTTILESIVPDKDVDGFHPYNVGRLSQRIPKLRSCTPKGIITLLERYNIPVRGKHAVIVGASNIVGRPMTFELLLAGATTTTCHRFTQDLEGHVRQADILVVAVGKPNFIPGEWIKEGATVIDVGINRLDTGKLCGDVEFNVAKTRAKYITPVPGGVGPMTVATLIENTLLACEQYHSDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWY7</accession>
    <name>D0YWY7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ribosomal-protein-S5p-alanine acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001820</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298768.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001820"/>
    <dbReference type="EnsemblBacteria" id="EEZ40788">
        <property type="protein sequence ID" value="EEZ40788"/>
        <property type="gene ID" value="VDA_001820"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1670">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1501005at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="31"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="198" mass="23512" checksum="5EC0AEC4D1323D53" modified="2010-01-19" version="1">MFHSIINRSFTIVVDELKIRLVTCKDAENIAIYYQKNRSHLQPWEPTREENFFTVAGWEKRLEQIAILHRHEMAYYFIVTPRHSNQVLAVINFSNVVKSPFYACHVGYSLDSEYQGKGIMRRALQATINWLFEEKHFHRIIAVYMPHNEKSANVLYSVGFEKEGEAKDYLLINGQWRDHILTAKINPNWREPIKWNPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-12-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX07</accession>
    <name>D0YX07_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Phage integrase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_002064</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299322.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002064"/>
    <dbReference type="EnsemblBacteria" id="EEZ41032">
        <property type="protein sequence ID" value="EEZ41032"/>
        <property type="gene ID" value="VDA_002064"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0582">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="785253at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0229">DNA integration</keyword>
    <keyword evidence="3" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyr recombinase" evidence="4">
        <location>
            <begin position="229"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="424" mass="49483" checksum="BC9EC6FF41D3D4B8" modified="2010-01-19" version="1">MLSSRTKIRINQQAFFSSTLPVKISDAQIKRHIDDLRVRQLKDIRCPLYLRFNQNRTGGTWWFYRYEKGKQYSHRLGAYPAIQAKDIMDVVSAASVKVAKEEIIECHRFETVDQLVAWHVERQRTLNQSSKARLVNLKSMAETHVMSIFHGVGVTDLTHQELDRLMIQPMFSEGYSVSYVRANFFLLKTAYSTAKRLKHISINPLADIQFKHFFPETFSITEAQIKGCRLSTEQLVRCLPLIAQALPPKRLLLTMMLAHGSRIGETRKARWKNINLSERSWFIPKEDSKNGVAMVYPLTTDMVELLRSYQVWQHHLGYKGDLLFPLSRWSKHPIHSSKASEWVREISDRQWSAHDLRKRARSIWAELGIDYIIGESLLNHSRDKLDQAYIHTHMELQKKEALETYQNWLKNCWCACLSPVSIQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX28</accession>
    <name>D0YX28_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hypothetical AcrB/AcrD/AcrF family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001903</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298905.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001903"/>
    <dbReference type="EnsemblBacteria" id="EEZ40871">
        <property type="protein sequence ID" value="EEZ40871"/>
        <property type="gene ID" value="VDA_001903"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0841">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="38744at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="338"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="362"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="392"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="434"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="462"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="865"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="891"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="917"/>
            <end position="938"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="970"/>
            <end position="988"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="994"/>
            <end position="1018"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="1031" mass="112963" checksum="4FB1E19792DCDAA9" modified="2010-01-19" version="1">MNKILANSRLLTLFIAIIIVSGISALMSLPRAEDPIIRNRNATITTVLPGATTERVESLVTEKIENQLRQLDEIALITSTSRPGISVVSIELQDTILDSEPVWSLVRDKLTDIEPQLPAGTLSPELDSDHSYAFTMIVALSWDHESEINLVTLRRYAKELSHRLRNLSGTEFVDEYGLIDEEILVSIDPTIATSLKRSAATLSEAIANADAKNAAGRLISPSANFTIEVSDSLDSLDRVKQVPVLVDSNGHVIRLRDIATVTHQPSYPMDEIALTQNHNKLQPNIIIAARMQPQLRVDQWSKKAHQIIEQFQQQLPHNIKAKVLFEQQGYTQQRLSELMGNLLLGFIIILFVLLLTLGARSAFIVALSLPLTSLLTLALMKYTNIPINQMSVTGLIVALGIMVDNAIVMVDTIAHYRHLGAKKIESAYKARRHLWLPLLGSTLTTILAFMPIILMPGAAGEFVGAIALTVSFSLAGSYLIAHTIVAGLAGRFLPKKEPSSAWYHTGITLPSLSCRFEKTLVWSVNHPLKTVLLSLLLPLLGFVGASQLTEQFFPPSDRDMFEIQVYLSPQSSIYHTQEFVQQLDSTLHQYSDIEQVQWVVGGNVPSFYYNMVGMQKGANNFAQAMVTASDFNAANRMIKTLQQQLPIDYPQAQILVRKLEQGPPFNAPIELRVQGNDLNQLKQIGDQLRLILAKHPAITETRSTLQFGLPKVAVSVNEEASQLSGLSLTQVAKLLQATLIGQNNGSVIQGQEEIPIRVRVADSQRENLSHLNNLLLPITNVNQAIGLPLSAIADLQLEPSLGAITRRNGNRVNTIEGYLIADVLPQTVLNQIEQELSQYQKTLPVGYKIDIGGESAERDESVNNLLANLSLVITLMIMVVVVSFNSFRLSMIIFAVSALAAGLGLLSVWVFQYPFGFTVIIALLGLIGLAINAAIVILSEFKADPAAREGNITAVVSGTMSCTRHITSTTITTVGGFLPLILAGGGFWPPFAVAIAGGTLLTTLLSFYFVPAMYCILVKHRKLTINKKALS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX48</accession>
    <name>D0YX48_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative AcrB Cation/multidrug efflux pump</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001842</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298798.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001842"/>
    <dbReference type="EnsemblBacteria" id="EEZ40810">
        <property type="protein sequence ID" value="EEZ40810"/>
        <property type="gene ID" value="VDA_001842"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0841">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="38744at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="14"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="335"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="363"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="390"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="436"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="466"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="527"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="863"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="889"/>
            <end position="909"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="915"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="957"/>
            <end position="979"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="991"/>
            <end position="1010"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="1021" mass="113154" checksum="7A1B410C713D44F6" modified="2010-01-19" version="1">MKQDIAAYFIRNKVVSWMVALIFLIGGTMSFFGLGRLEDPAFTIKDAMIVTSYAGATPMQVEEEVTYPIEKAIQQLSYVDEVNSISSRGLSQITVTMKNNYGPDDLPQIWDELRRKVNDLKPTLPPGVSEPKVIDDFGDVYGILLAITGDGYTYKELSDYVDYLRREVELVDGVGKVSVTGTQQEQVFIEISMRRLSNLGISPQTIYNTLATQNLVSSAGAVRIGDEYIRVHPTGEFKDVNELGNLIITEKGAEGLIYLRDVAEIKRGFKEIPDNLISFNGKQALNVGISFVSGVNVVEVGKKVEQRLAELKEQQPVGIDIDTVYSQPTEVDKSVSGFVLSLGESVAIVIIVLLFFMGLRSGLLIGLILLLTVLGTFVFMKWLAIDLQRISLGALVIALGMLVDNAIVVVEGILIGMQKGRTRMQAASDIVTQTKWPLLGATMIAVMAFAPIGLSQDSTGEYCRTLFTVLLISLMLSWFTAISLTPFFADLFFKNVKQDPNAEEVDPYAGKIFVWYRAFLEFCMRRAWLTVITLVLMLGASLYGFTLLKQSFFPASTTPMFMVDIWLPEGTDIRATNQTLEQLEKVVEKEQGVEYVSSSAGKGSQRFMLTYTPEKSYAAYGELIVRVKSFDDVIPVMRKFSAVLDKDHPKLEYKLKQVMLGPSSGSKIEARLVGPDPTVLRGLGKQVVDIMNADPGAFNIRHDWRERTKVIEPIFNESQARRYGITKQDVDDLFQMAFSGMAVGLYRDGTNLMPIVARLPEEERVDVSTIEGIKIWSPAIQGFIPLQQVILGVNVRWEDPLVVRKDRKRVLTVMADPDPLGDETAASVQARMQSKIESIEFPAGYALEWGGEYESSADAKASLFQTMPMGYLCMFLITILLFNKVKEALIVWATVPLAVIGVTLGLLLLNTPFGFMALLGFLSLSGMLVKNGIVLLDQIELEISSGKEKYQAIVDAAVSRVRPVCMAAITTILGMIPLLPDVFFKPMAVTIMFGLGFATILTLVVVPVLYRMFHHVRLPSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX77</accession>
    <name>D0YX77_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PEP-utilizers_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001936</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298970.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001936"/>
    <dbReference type="EnsemblBacteria" id="EEZ40904">
        <property type="protein sequence ID" value="EEZ40904"/>
        <property type="gene ID" value="VDA_001936"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1080">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="997616at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008986">
        <property type="term" value="F:pyruvate, water dikinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006090">
        <property type="term" value="P:pyruvate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006319">
        <property type="entry name" value="PEP_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000121">
        <property type="entry name" value="PEP_util_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43030">
        <property type="entry name" value="PTHR43030"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02896">
        <property type="entry name" value="PEP-utilizers_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PEP-utilizers_C" evidence="1">
        <location>
            <begin position="100"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="290" mass="33306" checksum="21E87AE49CC274F1" modified="2010-01-19" version="1">MINHNKNFAPVHFCPVHHSEGKKSADPILFFFDDIYLKLGIHPLALVEPNRLTHDEYEALTVNYDYENAAEWWLECVQQRLVELSDNGQVAIHICFSYADLHCYSDLIGAQLQPEELNPYLGMRGVSRFVSQPYKSVFELECEAIKRFMISTSNSLNVYIPYIRTSSESATAIDILAEQGLYRGVNGLKVHLLASLPANLLCADKLLHYFDGYVVDIKSLYQLTLGFDASNKQLHYSFDGRNEALHELLESVRSQTDKVNKPCAIFFRGLDEYPQFSRWLLENNIENIWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX79</accession>
    <name>D0YX79_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Multiphosphoryl transfer protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_001938</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II FruAB PTS system is involved in fructose transport.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298975.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001938"/>
    <dbReference type="EnsemblBacteria" id="EEZ40906">
        <property type="protein sequence ID" value="EEZ40906"/>
        <property type="gene ID" value="VDA_001938"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1925">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4668">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1810962at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00367">
        <property type="entry name" value="PTS-HPr_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00211">
        <property type="entry name" value="PTS_IIA_fru"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000032">
        <property type="entry name" value="HPr-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035895">
        <property type="entry name" value="HPr-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016152">
        <property type="entry name" value="PTrfase/Anion_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002178">
        <property type="entry name" value="PTS_EIIA_type-2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001020">
        <property type="entry name" value="PTS_HPr_His_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002114">
        <property type="entry name" value="PTS_HPr_Ser_P_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00381">
        <property type="entry name" value="PTS-HPr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00359">
        <property type="entry name" value="PTS_EIIA_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00107">
        <property type="entry name" value="PHOSPHOCPHPR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55594">
        <property type="entry name" value="SSF55594"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55804">
        <property type="entry name" value="SSF55804"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01003">
        <property type="entry name" value="PTS_HPr_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51094">
        <property type="entry name" value="PTS_EIIA_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00372">
        <property type="entry name" value="PTS_EIIA_TYPE_2_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51350">
        <property type="entry name" value="PTS_HPR_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00369">
        <property type="entry name" value="PTS_HPR_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00589">
        <property type="entry name" value="PTS_HPR_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0598">Phosphotransferase system</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PTS EIIA type-2" evidence="7">
        <location>
            <begin position="2"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="HPr" evidence="8">
        <location>
            <begin position="281"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ40906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="372" mass="39592" checksum="51D6795BB2CB07FA" modified="2010-01-19" version="1">MLSLTNNDIALEKAATNKTDAIRAIAADLTDAGLVEAGYVEGMLAREAQNSTFLGNGIAIPHGTTDTRELVKQTGVKVHHFPHGVDWGDGKTVYLAIGIAAKSDEHLGILKQLTKVLSADGVEQQLKDCQSADEIISILNGEQQTEVEFDPSLMKLNFPATDLVQLIAVAGGLIKNRQFASNKSVADAIAHGATYLGQGLWLARTSVDVSRTALAWVTVQNEFVEEGKSVKGLLLVAACNQAHVASLNLLAHLISKQKIAELLASSEDKVRVLLTEPLIEGESQVFTIHNPHGLHARPSAMLVNVAKQFNSNIHVVNLDGEGKGVNAKSLMKVITLGVKCGHRLEFTAQGDDADKALQAIGKAIEDGLGEGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX84</accession>
    <name>D0YX84_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative potassium channel related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001943</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001943"/>
    <dbReference type="EnsemblBacteria" id="EEZ40911">
        <property type="protein sequence ID" value="EEZ40911"/>
        <property type="gene ID" value="VDA_001943"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013099">
        <property type="entry name" value="K_chnl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07885">
        <property type="entry name" value="Ion_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0407">Ion channel</keyword>
    <keyword evidence="3" id="KW-0406">Ion transport</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="Ion_trans_2" evidence="2">
        <location>
            <begin position="65"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="379" mass="43441" checksum="EB87B31EC766A174" modified="2010-01-19" version="1">MATRLSITNTVDTLTYHFLLYFQKIFTSKISLKIRRNIVSLWILFQRWAVKHFTQLTGRNLLFALIGYILTSWILLFIANEIALTHSITDFIYYLFVTASTVGYGDLSPTTPTGKWIVALFIIPGGLGLFALTIGRVTSNLILYWRSGLLGRREVKLKNHILILGWNEKRTLHLIKMLQYEEKGYRPIVLCTRSEIENPLPGEIEFVRINHYTNIEEMRRTSLEQASCIIIDNPEDDITFTAALVCANYNPKAHILVYFNDDSLTPLLKLHCPNAECIPSVDVEMLAKSAIDPGSSKLHHELLSTHEGMTQYSVKYPIDKKTTQVSELFSHLKIEHDAILIAIENSNGIIVNPALSQEIRPEDTVYYIADERIRDFRWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX93</accession>
    <name>D0YX93_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Peptidase S8 and S53 subtilisin kexin sedolisin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_001952</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001952"/>
    <dbReference type="EnsemblBacteria" id="EEZ40920">
        <property type="protein sequence ID" value="EEZ40920"/>
        <property type="gene ID" value="VDA_001952"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1404">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="923655at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037045">
        <property type="entry name" value="S8pro/Inhibitor_I9_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0720">Serine protease</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018700" evidence="6">
        <location>
            <begin position="24"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S8" evidence="7">
        <location>
            <begin position="151"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="103"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ40920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="379" mass="39529" checksum="599552342D266D9B" modified="2010-01-19" version="1">MFIMKTLYAITSSVLLFTGTAVAQPVPFDLKNQFIIQFESSISNEKRHAIALEITNAKGQVHHHYSHALQGMSITLPPQALTKLQERFGDAIIHIEKNQIVSLAKPGNGKGGGGKGDGDSGSTTPRAPEVIPWGVSRVGGPQIAEYGTAWVIDTGIDSRHPDLNVDKNRGANFIRGKNTTEDDNGHGTHVAGTIAAKVDGYDVVGVAAGATVIPVRVLDNNGSGTMDGVIAGVDHVYRNGQYGDCANMSLGAQGFSSALDTAIKAAANKGIIFAVAAGNSSANAATFTPASTTHPNVFTISSVGQYDNFSWFSNYGSVVEYALPGENILSTKTGGGTVAYNGTSMAAPHFCGLAIIGSYYINAYANNDPDGSPDPIPSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXF3</accession>
    <name>D0YXF3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Oligopeptide ABC transporter periplasmic oligopeptide-binding protein OppA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001632</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298410.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001632"/>
    <dbReference type="EnsemblBacteria" id="EEZ40605">
        <property type="protein sequence ID" value="EEZ40605"/>
        <property type="gene ID" value="VDA_001632"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4166">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="162819at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030678">
        <property type="entry name" value="Peptide/Ni-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002741">
        <property type="entry name" value="MppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019205" evidence="1">
        <location>
            <begin position="28"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="domain" description="SBP_bac_5" evidence="2">
        <location>
            <begin position="83"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="542" mass="60605" checksum="9FFC8058C9F84456" modified="2010-01-19" version="1">MYKNKITQALWMSAGLAVSAGSFSVVAAQVPEGVKLADSQELVRNNGSEVESLDPQKVSGVPESNIIRDLLEGLINQDDKGNLVPGAASSWESSDNKVWTFHLRQDAKWSNGDPVTAEDFVYTWRRLADPKTASPYASYLSMTTMHNAEAIINGKAAPDSLGVEAVDPHTLKVTLDKAVPYFPAMLVHTSMKPVHAKTVAAHGDKWTSVDNYVSNGAYKLDKWVVNERIELVRNENYWDNKETIINKVTYLPIENQVAAMNRFLAGEIDLTYEVPNEHFKRLVKEHPDAVKVTPYLCSYYYEFNTARKPFDDVRVRKALSYAIDRDVIAKFIVGKGETPAYNFTPLATNGIEVDLPDYSSLSQKERVAKAKELLKEAGYGDKPLTFDLLYNTSENHKKIAVAIASMWKKSLGVTANLENQEWKSYLDSKRQGNFDVSRAGWCGDYNEASTFLAIMRDGHSQNYPKYTSKAYDKALDDALAAASIESRAQAYKNAESLLATDMPIMPIYHYVNARLVNPKVGGYPMKNPEDNIYSKDLYIIAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXG2</accession>
    <name>D0YXG2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001697</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298533.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001697"/>
    <dbReference type="EnsemblBacteria" id="EEZ40668">
        <property type="protein sequence ID" value="EEZ40668"/>
        <property type="gene ID" value="VDA_001697"/>
    </dbReference>
    <dbReference type="GeneID" id="57342221"/>
    <dbReference type="eggNOG" id="COG3753">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1984170at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.690">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045372">
        <property type="entry name" value="YidB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027405">
        <property type="entry name" value="YidB-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20159">
        <property type="entry name" value="YidB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140804">
        <property type="entry name" value="SSF140804"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="150" mass="15193" checksum="2D385819550B9682" modified="2010-01-19" version="1">MDITKILEIGAQLFSQSQANTGGLNQGSIVSALSRLLGGDENGQGVNFEQLLSSINGAGLANVLQSWLGNGENNAISADDIANIFSGSQLSDFANELNLSEQDAKTGLSEALPAMVDNASPAGEIAGELLNAVGGVSGLLNMAAGLFGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXL6</accession>
    <name>D0YXL6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001757</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40725">
        <property type="protein sequence ID" value="EEZ40725"/>
        <property type="gene ID" value="VDA_001757"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="43" mass="4633" checksum="246DE6CEFC10411D" modified="2010-01-19" version="1">MLIGLAIFAIKYLDANGQKKVVIGLVSILTLGVVTLMTMELLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXN0</accession>
    <name>D0YXN0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative multidrug resistance protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_001771</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298669.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001771"/>
    <dbReference type="EnsemblBacteria" id="EEZ40739">
        <property type="protein sequence ID" value="EEZ40739"/>
        <property type="gene ID" value="VDA_001771"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1118058at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="80"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="107"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="132"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="162"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="215"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="248"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="276"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="301"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="338"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="364"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="12"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="402" mass="43940" checksum="F12CCB49C7891F02" modified="2010-01-19" version="1">MIEKNTPAYRRASFALAFGSFLVFCNLYLFQPMLPVMAQHFAVSETQINWLLAGGTLMLAITLVPWAVGSEIIGRRKVMMISLFLLPVIGVAMVFADNLFWLTIARALMGAALAGFAAVAVAYMAEEFTPTALMLAVGSYISANSLGGISGRLYGGFMTEHFGWHAAVIGMAIFSLFGALLVNYLLPQQQHFVAKKGQLKQHTQAAIFHLRQPKLWFAMILGGINFALFVNLYSVMGFRLVAPPYNLPVSYASMIFLCYLTGTVTARLSGRWAEKFGSISGMVLGITISMLGMWVALIDSIYAMLIALLLISSGAFLTHSLAYAWVSHKATDAKATATALYLVHYYVGGSLGGFFLIYCWQHGAWLGVVTGGSVLYLLAYVICWWLHRSHTSQVNQSVATAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXV1</accession>
    <name>D0YXV1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Spermidine/putrescine import ATP-binding protein PotA</fullName>
            <ecNumber evidence="9">7.6.2.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">potA</name>
        <name evidence="11" type="ORF">VDA_002114</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.</text>
    </comment>
    <dbReference type="EC" id="7.6.2.11" evidence="9"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299476.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002114"/>
    <dbReference type="EnsemblBacteria" id="EEZ41082">
        <property type="protein sequence ID" value="EEZ41082"/>
        <property type="gene ID" value="VDA_002114"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1200451at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015594">
        <property type="term" value="F:ABC-type putrescine transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03300">
        <property type="entry name" value="ABC_PotA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017879">
        <property type="entry name" value="PotA_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005893">
        <property type="entry name" value="Sp_pt_ABC_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013611">
        <property type="entry name" value="Transp-assoc_OB_typ2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08402">
        <property type="entry name" value="TOBE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01187">
        <property type="entry name" value="potA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="2 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-1278">Translocase</keyword>
    <keyword evidence="1 9" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="12"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="44"/>
            <end position="51"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ41082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="372" mass="41664" checksum="974F867251987CE1" modified="2010-01-19" version="1">MNAATTSKKPVIQLKGLGKSFDGKQIISGLDLNVNDGEFLTILGPSGCGKTTVLRLIAGFENADNGQVIIDGKDVTSIPAEQRHVNTVFQSYALFPHMTVFDNVAFGLRMQNVSASEIEPRVMEALRMVQLDKFAPRKPHQLSGGQQQRVAIARAVVNKPKVLLLDESLSALDYKLRKQMQIELKQLQRKLGITFIFVTHDQEEALSMSDRIIVMRDGNVEQDGSPREIYEEPTNLFVARFIGEINVFDAIVKERVDEKRILADVEGRRATILCDLDVNPGDKVKVLLRPEDIRIEEIHNGDSVSGILGYVRERTYKGMTLDSVVQLESGKNVMVSEFFNEDDPDVDHSLDQKVAITWVESWEVVLADEQEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXX7</accession>
    <name>D0YXX7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative lipase/esterase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_002140</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 'GDXG' lipolytic enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002140"/>
    <dbReference type="EnsemblBacteria" id="EEZ41108">
        <property type="protein sequence ID" value="EEZ41108"/>
        <property type="gene ID" value="VDA_002140"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0657">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002168">
        <property type="entry name" value="Lipase_GDXG_HIS_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033140">
        <property type="entry name" value="Lipase_GDXG_put_SER_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01173">
        <property type="entry name" value="LIPASE_GDXG_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01174">
        <property type="entry name" value="LIPASE_GDXG_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Abhydrolase_3" evidence="5">
        <location>
            <begin position="76"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="308"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="331" mass="36669" checksum="4C6B74C3192113C1" modified="2010-01-19" version="1">MDNWRTRAFNKLLFRIMRQRMARCETTQEMRELIASIDSYGALFSSPKSLTISPTKFADVSCDWVDMSTSRGNRILLYFHGGGFCFTSPKTHTSFLGRIARGSQSRGLMVNYSLSPEYPYPQAVNEAFAVYNQLLINGYLPDHIFIAGDSAGGNLALTTLVKIRNEGLVMPAGAALLSPVSDMAVTGESAFTKSKDDPFFDLSSLLLMRNNYIGTQNPCNPEVSPFYAELHDLPPIYITVGTEEILMDDSIRLAEKIEQAGGKVTLDVVKGVPHVYPLFNQLSEAEQAVQVISAFIEDCYQKAKLSNQCGDESDNIKSSRVNAQNKKKRTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY30</accession>
    <name>D0YY30_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002193</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299623.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002193"/>
    <dbReference type="EnsemblBacteria" id="EEZ41161">
        <property type="protein sequence ID" value="EEZ41161"/>
        <property type="gene ID" value="VDA_002193"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502Z7JK">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="556139at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025964">
        <property type="entry name" value="GGGtGRT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14057">
        <property type="entry name" value="GGGtGRT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="333" mass="35751" checksum="0BB3EBE48C06BFC3" modified="2010-01-19" version="1">MAALFESFDRRINQITPVLEKYGFASLEEARQFVEDKGVRAYDIVKETQPIAFENASWAYVLGAAIALKEGAKNAAEAAEYLGQGLQAFCIPGSVADQRQVGLGHGRLGARLLSDETQCFCFLAGHESYAAAEGAIKIALNANKVRKNPLRVILNGLGKDAAYLIARINGFNYVQTQFNYSTGELEIVNERRFSKSQRGDINCYGADDVREGVAIMHRENVDISITGNSTNPTRFQHPVAGTYKKERLESGLGYFSVASGGGTGRTLHPDNVAAGPASYGMTDTMGRMHSDAQFAGSSSVPAHVEMMGLIGMGNNPMVGATVAVAVAIEQAQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY72</accession>
    <name>D0YY72_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Bcr/CflA family efflux transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_002235</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell inner membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Bcr/CmlA family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299707.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002235"/>
    <dbReference type="EnsemblBacteria" id="EEZ41203">
        <property type="protein sequence ID" value="EEZ41203"/>
        <property type="gene ID" value="VDA_002235"/>
    </dbReference>
    <dbReference type="GeneID" id="57341611"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1452500at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990961">
        <property type="term" value="P:xenobiotic detoxification by transmembrane export across the plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004812">
        <property type="entry name" value="Efflux_drug-R_Bcr/CmlA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00710">
        <property type="entry name" value="efflux_Bcr_CflA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="9"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="100"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="133"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="161"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="212"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="242"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="277"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="304"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="338"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="365"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="8">
        <location>
            <begin position="9"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="402" mass="43476" checksum="50000E04AE0EF9C4" modified="2010-01-19" version="1">MNQQPSKMTLIWFACLSMLGFLATDMYLPAFETIRVAFGTTQSLIGLTLSVFLLGMALGQLVYGPLSDRIGRKKVLLGGMALFSVATLLCSIAPNIETFLIARFVQALGACSATVIWQAVVVDRYHGKTSERIFATIMPLVALSPALAPLAGAMLEHQLGWRSIFITLVAFGVIMCVMTLSEKESAPIDKEHEKVSIQLRRDYRDILSSKKFVGNMLIFAACSAAFFAYLTGSPFVMSAMGYSGADIGLSYAPQTVAFIVGGYGCRTLLNRYEGRQILPWLLVLFFASVLIMFVISISMEVTTIWPILIPFCLLAVANGAIYPIVINSALGDFKHCSATAAGLLNFLQTMVCFAASGLVSTFAGYGLITVTTGMFIAGFVTLIGYSFVKSAHHQQSMKPAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY87</accession>
    <name>D0YY87_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Sulfurtransferase</fullName>
            <ecNumber evidence="3">2.8.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_002250</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Part of a sulfur-relay system.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the dsrC/tusE family.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.-" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299735.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002250"/>
    <dbReference type="EnsemblBacteria" id="EEZ41218">
        <property type="protein sequence ID" value="EEZ41218"/>
        <property type="gene ID" value="VDA_002250"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2920">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1840461at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042072">
        <property type="entry name" value="DsrC-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025526">
        <property type="entry name" value="DsrC-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043163">
        <property type="entry name" value="DsrC-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007453">
        <property type="entry name" value="DsrC/TusE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37010">
        <property type="entry name" value="PTHR37010"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04358">
        <property type="entry name" value="DsrC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006223">
        <property type="entry name" value="DsrC_TusE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69721">
        <property type="entry name" value="SSF69721"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03342">
        <property type="entry name" value="dsrC_tusE_dsvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Cysteine persulfide intermediate" evidence="4">
        <location>
            <position position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR006223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR006223-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="109" mass="12554" checksum="209927DDD5453729" modified="2010-01-19" version="1">MLEFEDNQIETDAQGYLKNVDDWSKELVTLLAEEEGIELTEAHWEVIHFVREFYLEFNTSPAIRMLVKAMAKQYGEEKGSSRYLYKLFPKGPAKQATKLAGLPKPVKCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYD7</accession>
    <name>D0YYD7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hypothetical ATP-dependent protease La (LON) domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299820.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002300"/>
    <dbReference type="EnsemblBacteria" id="EEZ41268">
        <property type="protein sequence ID" value="EEZ41268"/>
        <property type="gene ID" value="VDA_002300"/>
    </dbReference>
    <dbReference type="GeneID" id="57341516"/>
    <dbReference type="eggNOG" id="COG2802">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1474822at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003111">
        <property type="entry name" value="Lon_prtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046336">
        <property type="entry name" value="Lon_prtase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02190">
        <property type="entry name" value="LON_substr_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00464">
        <property type="entry name" value="LON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51787">
        <property type="entry name" value="LON_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lon N-terminal" evidence="1">
        <location>
            <begin position="4"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="188" mass="21686" checksum="097E1685C66376DB" modified="2010-01-19" version="1">MQQLPLFPLKLYLLPGGISQLRIFEPRYTRLVKLAMTTGEGFGLCMIEHEQICRFGTRVVITDFETLDDGFLGITVEAVDKFVITDYQQDNDGLYMANIETFPNWPNASVDFSDNDLVESLKAVFIEYPEHSAHYPAPQFDNISWVCQRWLEVLPLEINQKQWFISRSDHLPAVSFLHSVINETNTDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYS0</accession>
    <name>D0YYS0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Peptidoglycan-associated protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">pal</name>
        <name evidence="13" type="ORF">VDA_002433</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the Pal lipoprotein family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300081.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002433"/>
    <dbReference type="EnsemblBacteria" id="EEZ41401">
        <property type="protein sequence ID" value="EEZ41401"/>
        <property type="gene ID" value="VDA_002433"/>
    </dbReference>
    <dbReference type="GeneID" id="57341353"/>
    <dbReference type="eggNOG" id="COG2885">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1544679at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07185">
        <property type="entry name" value="OmpA_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02204">
        <property type="entry name" value="Pal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006664">
        <property type="entry name" value="OMP_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006665">
        <property type="entry name" value="OmpA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006690">
        <property type="entry name" value="OMPA-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036737">
        <property type="entry name" value="OmpA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039001">
        <property type="entry name" value="Pal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014169">
        <property type="entry name" value="Pal_lipo_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00691">
        <property type="entry name" value="OmpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01021">
        <property type="entry name" value="OMPADOMAIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103088">
        <property type="entry name" value="SSF103088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02802">
        <property type="entry name" value="Pal_lipo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01068">
        <property type="entry name" value="OMPA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51123">
        <property type="entry name" value="OMPA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1 8" id="KW-0132">Cell division</keyword>
    <keyword evidence="5" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="6 13" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0564">Palmitate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019248" description="Peptidoglycan-associated protein" evidence="11">
        <location>
            <begin position="21"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="OmpA-like" evidence="12">
        <location>
            <begin position="65"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="26"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ41401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="181" mass="19543" checksum="75F1C32D256FB131" modified="2010-01-19" version="1">MQLNKVLKSLAIALPLMTLAACSSTEGTNSSAADQTAGGSSSMVDQGAISTPVDGGNGSMSEQEIRNQQLRQETTVFFKFDNAEIQPEYQAMLEAHAEYLRDHPAVKVIIEGHADERGTPEYNIALGERRAAAVVKYLQALGVPASQMSIVSYGEEKPLVLGHTDADYAKNRRAVLVYKTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYU8</accession>
    <name>D0YYU8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Cysteine--tRNA ligase</fullName>
            <ecNumber evidence="12">6.1.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Cysteinyl-tRNA synthetase</fullName>
            <shortName evidence="12">CysRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">cysS</name>
        <name evidence="14" type="ORF">VDA_002461</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>ATP + L-cysteine + tRNA(Cys) = AMP + diphosphate + L-cysteinyl-tRNA(Cys)</text>
            <dbReference type="Rhea" id="RHEA:17773"/>
            <dbReference type="Rhea" id="RHEA-COMP:9661"/>
            <dbReference type="Rhea" id="RHEA-COMP:9679"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78517"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4 12">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.16" evidence="12"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002461"/>
    <dbReference type="EnsemblBacteria" id="EEZ41429">
        <property type="protein sequence ID" value="EEZ41429"/>
        <property type="gene ID" value="VDA_002461"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0215">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004817">
        <property type="term" value="F:cysteine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006423">
        <property type="term" value="P:cysteinyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00672">
        <property type="entry name" value="CysRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00041">
        <property type="entry name" value="Cys_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015803">
        <property type="entry name" value="Cys-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015273">
        <property type="entry name" value="Cys-tRNA-synt_Ia_DALR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024909">
        <property type="entry name" value="Cys-tRNA/MSH_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032678">
        <property type="entry name" value="tRNA-synt_1_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10890">
        <property type="entry name" value="PTHR10890"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09190">
        <property type="entry name" value="DALR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01406">
        <property type="entry name" value="tRNA-synt_1e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00983">
        <property type="entry name" value="TRNASYNTHCYS"/>
    </dbReference>
    <dbReference type="SMART" id="SM00840">
        <property type="entry name" value="DALR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00435">
        <property type="entry name" value="cysS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12 14" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="9 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 12 14" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10 12" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="DALR_2" evidence="13">
        <location>
            <begin position="292"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="12">
        <location>
            <begin position="217"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEZ41429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="410" mass="46361" checksum="F37391A19BC946B7" modified="2010-01-19" version="1">MSRYLRYLGYDLTFVRNITDIDDKIIKRAAENGETCDSLTERLIGEMHADFDALGMKRPDVEPRATAFISEIIALCERLIERGFAYVADNGDVMFEVSKFKDYGRLSKQDLDQLQAGARVDIELAKRSPLDFVLWKMSKPGEPTWESPWGPGRPGWHIECSAMNSAILGDHFDIHGGGSDLQFPHHENEIAQSCCAHDTQYVNTWMHSGMVMVDREKMSKSLGNFFTIRDVLNHYDPETVRYFLMSGHYRSQLNYSEDNLKQARSALERLYTSLRGLDTSVEAAGGEEFVARFKEAMDDDFNTPEAYSVLFDMAREINRLKTDDMAAASVLGARMRELADVLGLLGQEPEVFLQSGANDDDVAEIEALIQQRLDARAAKDWAAADQARDKLTEMGIILEDGPQGTTWRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYX2</accession>
    <name>D0YYX2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">tRNA threonylcarbamoyladenosine biosynthesis protein TsaB</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaB</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_002485</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the KAE1 / TsaD family. TsaB subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002485"/>
    <dbReference type="EnsemblBacteria" id="EEZ41453">
        <property type="protein sequence ID" value="EEZ41453"/>
        <property type="gene ID" value="VDA_002485"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1214">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002949">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000905">
        <property type="entry name" value="Gcp-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022496">
        <property type="entry name" value="T6A_TsaB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735">
        <property type="entry name" value="PTHR11735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735:SF11">
        <property type="entry name" value="PTHR11735:SF11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00814">
        <property type="entry name" value="TsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03725">
        <property type="entry name" value="T6A_YeaZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TsaD" evidence="4">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00032446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="191" mass="20594" checksum="AB499C04326A53E5" modified="2010-01-19" version="1">MVDSVLAEAGVKLNQLDALAYGRGPGSFTGVRIGIGIAQGLAFGADLPMIGVSTLAAMAQGSYRTEQAEQVVAAIDARMGEVYWGQYQRQQDGDWAVLGAELVIEPKALPEMVQTESGIWLTAGTGWESYAEEMSNLPLELKTGAMLYPEAQDMAFLAQFAFARGEMVPAEEASPVYLRDTVTWKKLPGRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYZ5</accession>
    <name>D0YYZ5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Negative modulator of initiation of replication</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">seqA</name>
        <name evidence="8" type="ORF">VDA_002508</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5">Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re-initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer. Polymerizes to form helical filaments.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4 5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the SeqA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002508"/>
    <dbReference type="EnsemblBacteria" id="EEZ41476">
        <property type="protein sequence ID" value="EEZ41476"/>
        <property type="gene ID" value="VDA_002508"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3057">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032297">
        <property type="term" value="P:negative regulation of DNA-templated DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00908">
        <property type="entry name" value="SeqA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013321">
        <property type="entry name" value="Arc_rbn_hlx_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005621">
        <property type="entry name" value="SeqA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026577">
        <property type="entry name" value="SeqA_DNA-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036835">
        <property type="entry name" value="SeqA_DNA-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033761">
        <property type="entry name" value="SeqA_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03925">
        <property type="entry name" value="SeqA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17206">
        <property type="entry name" value="SeqA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019401">
        <property type="entry name" value="SeqA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82808">
        <property type="entry name" value="SSF82808"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4 5" id="KW-0236">DNA replication inhibitor</keyword>
    <keyword evidence="3 4 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SeqA_N" evidence="7">
        <location>
            <begin position="5"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="domain" description="SeqA" evidence="6">
        <location>
            <begin position="75"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with DNA" evidence="4">
        <location>
            <begin position="120"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR019401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ41476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="185" mass="20891" checksum="8686A2F5D4EB51DE" modified="2010-01-19" version="1">MKTTMKTIEVDEELYRFIASQTQHIGESASDILRRLLMMPDTQYQPQPEVVMPVRPRGIVVSKDAGNEPQLDRVKEMRSLLISDEFAAQEKAIGRFMLILSSLYRIDSKGFTEAAAIKGRTRIYFAEDEATLLASGKTTKPKAIAGTPFWVITNTNTDRKRQMIDQLMVKMGFAQDIVDKVCGEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ27</accession>
    <name>D0YZ27_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Di-/tripeptide transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_002540</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Membrane</location>
            <topology evidence="1 5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300286.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002540"/>
    <dbReference type="EnsemblBacteria" id="EEZ41508">
        <property type="protein sequence ID" value="EEZ41508"/>
        <property type="gene ID" value="VDA_002540"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3104">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="470322at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904680">
        <property type="term" value="F:peptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006857">
        <property type="term" value="P:oligopeptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17346">
        <property type="entry name" value="MFS_DtpA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005279">
        <property type="entry name" value="Dipep/tripep_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000109">
        <property type="entry name" value="POT_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018456">
        <property type="entry name" value="PTR2_symporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11654">
        <property type="entry name" value="PTHR11654"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00854">
        <property type="entry name" value="PTR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00924">
        <property type="entry name" value="yjdL_sub1_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01022">
        <property type="entry name" value="PTR2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01023">
        <property type="entry name" value="PTR2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="49"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="146"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="214"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="237"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="267"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="347"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="377"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="414"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="454"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="493" mass="53652" checksum="FE5135144CBDD7A0" modified="2010-01-19" version="1">MSDLNVFKQPKQFYLIFSIEFWERFGFYGMQAILTVYLVQILGMSESKSFVLFGAFSALVYGSVAIGGWVGDKVIGTKRTITLGAVVLTVGYALLGLSAMANFGGESLIYVAMGFITMGNGLFKANPSSLLAKVYDDGDARLDGAFTMYYMAINLGSFFSMLLTPWIAEKMGYDIAFGISAVGLVITVINFMMCSKMVKDVGSEPDLAPVNKKHYLGVVISAIALSFVSAILLQHLFYAHAILVVVGCSIVFLYLKEAFSISGLERAKMLVAFVLMLQGVVFFVLYFQMPTSLNFFAIHNIEHNIFGISVQPEQFQALNPFWIMIASPILAMMYNNMGERFAMPYKFAMGMVLCSLSFLVLTFGAKFANAQGIMSSNWLIICYGFQSIGELLVSGLGLAMVAQLVPQRMMGFAMGMWFLTSATAAVVAGWVATLTTAPAGITDSHQTLTIYSDVFAKIGYSTAAIAVLTLLIAPKLTRIIRGETQAATEQATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZJ2</accession>
    <name>D0YZJ2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Nucleoside diphosphate kinase</fullName>
            <ecNumber evidence="4">2.7.4.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_002705</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the NDK family.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.6" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002705"/>
    <dbReference type="EnsemblBacteria" id="EEZ41673">
        <property type="protein sequence ID" value="EEZ41673"/>
        <property type="gene ID" value="VDA_002705"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0105">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004550">
        <property type="term" value="F:nucleoside diphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006241">
        <property type="term" value="P:CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006183">
        <property type="term" value="P:GTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006165">
        <property type="term" value="P:nucleoside diphosphate phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006228">
        <property type="term" value="P:UTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.141">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034907">
        <property type="entry name" value="NDK-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036850">
        <property type="entry name" value="NDK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001564">
        <property type="entry name" value="Nucleoside_diP_kinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00334">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01243">
        <property type="entry name" value="NUCDPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00562">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54919">
        <property type="entry name" value="SSF54919"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NDK" evidence="3">
        <location>
            <begin position="1"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="115" mass="12718" checksum="E3D6CE74C4F653B4" modified="2010-01-19" version="1">MENAGFKIVAAKMIHMTSEQAQGFYAEHEGKPFFDELVAYMTSGPVMVQVLEGENAVVRYRELMGKTNPEEAACGTLRADFALSLRHNSVHGADSPESAAREIAYFFADDEILSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZP3</accession>
    <name>D0YZP3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acyl-CoA dehydrogenase</fullName>
            <ecNumber evidence="4">1.3.99.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_002756</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="1.3.99.3" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002756"/>
    <dbReference type="EnsemblBacteria" id="EEZ41724">
        <property type="protein sequence ID" value="EEZ41724"/>
        <property type="gene ID" value="VDA_002756"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1960">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043958">
        <property type="term" value="F:acryloyl-CoA reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="3">
        <location>
            <begin position="236"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="563" mass="65005" checksum="59653EE1B3DCEC88" modified="2010-01-19" version="1">MLFNPQKHNFHYKDQETQQLMQKVIDFFEAKGLKSIKKDWHDKVWNYEFVDFMKDNQVLATLMTPEGYGDPSARWDTYRNTKFAEIIGFYGITYWYTFQVSMLGVAPVWLGSNEELKHKAAQLLQEGHVCAFGLSEKEHGADIYSSEMKLVDKGNGYFEGSGSKYYIGNGNEAGLVSTFGKVENSDDYVFFVVDSKHPQYTCVKNTVNEQIHVSEYTINHYPITAEDISERGQKAWDDMLNTINICKFNLGFASIGLCEHAFYEAINHAAHRNIYGKYVTDFPHIQRLFADAYARLCAMKLFSERACDYMRSASQDDRRYLLFNPMVKMKVTSQGEEVINHLWDVIAAKGFEQEPFFETAAHEIRMLPKLEGTVHVNMALVVKFMQNYLFNPKDYPVIPHRDDVANDDFLFNQGPTRGLGKIQFHDYQQTYDAVKLENVEIFKQQIAAFKDYLLHHSPSQDQARDVDYILAMGECFTLIVYGHLILERAQHLATEDILINEIFDVLVRDMSHYALTLANKPSSTSGQYSALRLIQHKPHHDQERFKALWQSIYSLSGTYTALD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZR5</accession>
    <name>D0YZR5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Polyketide_cyc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_002778</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ribosome association toxin RatA family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002778"/>
    <dbReference type="EnsemblBacteria" id="EEZ41746">
        <property type="protein sequence ID" value="EEZ41746"/>
        <property type="gene ID" value="VDA_002778"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2867">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005031">
        <property type="entry name" value="COQ10_START"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03364">
        <property type="entry name" value="Polyketide_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-1277">Toxin-antitoxin system</keyword>
    <feature type="domain" description="Polyketide_cyc" evidence="3">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="69" mass="7677" checksum="876A54B7637CBE46" modified="2010-01-19" version="1">MQLVDGPFKKLVGGWTFTELDASACKVELNLDFEFANGLMDAAFGKVFRDLTNNMMGAFTSRAKEIYGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZU5</accession>
    <name>D0YZU5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative SerB-cotransposed membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_002808</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Smp family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301066.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002808"/>
    <dbReference type="EnsemblBacteria" id="EEZ41776">
        <property type="protein sequence ID" value="EEZ41776"/>
        <property type="gene ID" value="VDA_002808"/>
    </dbReference>
    <dbReference type="GeneID" id="57340913"/>
    <dbReference type="eggNOG" id="COG3726">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019305">
        <property type="entry name" value="Uncharacterised_Smp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10144">
        <property type="entry name" value="SMP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="204" mass="22963" checksum="42EBEE6D0FE56D65" modified="2010-01-19" version="1">MWKLNKSRWPRFKQLGVLLFSLIGVIGMLEYGARLTQDNYEMLGEQTQALSRILVRQAAETAAPDILDNDQDKLQDLVQQLSKEPLILDASVYNLEGQTLAKTEGSMPLEQVTGLSTPLAVASIGRQQIVEPIFSDQHMVGFLRITLEHDKLLAHASSQIEYMTTIIRGLVIFAIGLGFLLAFTFGRRKDIWHFPFLMTANSKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZW8</accession>
    <name>D0YZW8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">tRNA pseudouridine synthase B</fullName>
            <ecNumber evidence="5">5.4.99.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">tRNA pseudouridine(55) synthase</fullName>
            <shortName evidence="5">Psi55 synthase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">tRNA pseudouridylate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">tRNA-uridine isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">truB</name>
        <name evidence="9" type="ORF">VDA_002831</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>uridine(55) in tRNA = pseudouridine(55) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:42532"/>
            <dbReference type="Rhea" id="RHEA-COMP:10101"/>
            <dbReference type="Rhea" id="RHEA-COMP:10102"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="EC" id="5.4.99.25"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.25" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301139.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002831"/>
    <dbReference type="EnsemblBacteria" id="EEZ41799">
        <property type="protein sequence ID" value="EEZ41799"/>
        <property type="gene ID" value="VDA_002831"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0130">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1166299at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106029">
        <property type="term" value="F:tRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031119">
        <property type="term" value="P:tRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02573">
        <property type="entry name" value="PseudoU_synth_EcTruB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01080">
        <property type="entry name" value="TruB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002501">
        <property type="entry name" value="PsdUridine_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036974">
        <property type="entry name" value="PUA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014780">
        <property type="entry name" value="tRNA_psdUridine_synth_TruB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015240">
        <property type="entry name" value="tRNA_sdUridine_synth_fam1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032819">
        <property type="entry name" value="TruB_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13767">
        <property type="entry name" value="PTHR13767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09157">
        <property type="entry name" value="TruB-C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16198">
        <property type="entry name" value="TruB_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01509">
        <property type="entry name" value="TruB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00431">
        <property type="entry name" value="TruB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TruB_N" evidence="6">
        <location>
            <begin position="32"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="TruB_C_2" evidence="8">
        <location>
            <begin position="180"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="TruB-C_2" evidence="7">
        <location>
            <begin position="251"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF09157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF16198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="315" mass="35033" checksum="9E9F9B56D994FFFF" modified="2010-01-19" version="1">MARRRKGRPIDGVILVDKPTGISSNDTLQKVKRIFFAQKAGHTGALDPLATGMLPICFGEATKFSQFLLDSDKRYRVIAKLGERTDTSDSDGQVVETRDVKVDRGQLERCIAKFRGTTDQIPSMYSALKYKGRKLYEYAREGVEVPRESRKITVYSVDLLRFDSNEVEMELHVSKGTYIRTIVDDLGEMLGCGAHVIMLRRIGVSHYPVDRMVTIEQLALLADQTKEKGIDPHTVLDTLLLPTDTAVQDLPEVNILPAQAVYALHGNPVRAARIPEEGTLVRITVGEKRDFIGVGTIEKGMLAPKRVIAEQQAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z001</accession>
    <name>D0Z001_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Lysine--tRNA ligase</fullName>
            <ecNumber evidence="7">6.1.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Lysyl-tRNA synthetase</fullName>
            <shortName evidence="7">LysRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">lysS</name>
        <name evidence="10" type="ORF">VDA_002864</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7 8">
            <text>ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys)</text>
            <dbReference type="Rhea" id="RHEA:20792"/>
            <dbReference type="Rhea" id="RHEA-COMP:9696"/>
            <dbReference type="Rhea" id="RHEA-COMP:9697"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78529"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7 8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="7 8">Binds 3 Mg(2+) ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.6" evidence="7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301238.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002864"/>
    <dbReference type="EnsemblBacteria" id="EEZ41832">
        <property type="protein sequence ID" value="EEZ41832"/>
        <property type="gene ID" value="VDA_002864"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1190">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="63621at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004824">
        <property type="term" value="F:lysine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006430">
        <property type="term" value="P:lysyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00775">
        <property type="entry name" value="LysRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04322">
        <property type="entry name" value="LysRS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00252">
        <property type="entry name" value="Lys_tRNA_synth_class2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002313">
        <property type="entry name" value="Lys-tRNA-ligase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034762">
        <property type="entry name" value="Lys-tRNA-ligase_II_bac/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044136">
        <property type="entry name" value="Lys-tRNA-ligase_II_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018149">
        <property type="entry name" value="Lys-tRNA-synth_II_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039101">
        <property type="entry name" value="LysRS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00982">
        <property type="entry name" value="TRNASYNTHLYS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00499">
        <property type="entry name" value="lysS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 7 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="7 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="9">
        <location>
            <begin position="173"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="410"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ41832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="500" mass="57011" checksum="F4A576C98AAEA829" modified="2010-01-19" version="1">MTDQVQDENKLIAERRAKLDMIRKDCKANGHPNDFRRDSLAADLQAKFGEMTKEELEEAKQVVAIAGRIMAKRGPFLAIQDVTGRIQAYASKDVQKELKDKYSGLDIGDIIGIKGELHKSGKGDLYVNMDQYELLTKALRPLPEKFHGLTDQEMRYRQRYVDLIVNDDSRKAFKIRSQVVSAIRSFMVTKGFMEVETPMMHVIPGGATARPFITHHNALDIDMYLRVAPELYLKRLVVGGFERVFEINRNFRNEGLSPRHNPEFTMMEFYMAYADYRDLMDLTEEMLSSIAIEVLGSSKMPYGDFEVEFAGPYTRMSMLDAIKHYNPDHAEIQALTYEGVADRELMVKIAKSVHVDVEDFWTCGQLLEEIFGETAEPQLMQPTFITEYPADISPLARRNDENPFITDRFEFFIGGREVANGFSELNDAQDQDQRFKAQVDAKDAGDDEAMYYDADYITALEHGLPPTAGQGIGIDRLVMLFTNTHTIRDVILFPAMRPQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z076</accession>
    <name>D0Z076_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Bifunctional protein HldE</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="11">D-beta-D-heptose 7-phosphate kinase</fullName>
                <ecNumber evidence="11">2.7.1.167</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="11">D-beta-D-heptose 7-phosphotransferase</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="11">D-glycero-beta-D-manno-heptose-7-phosphate kinase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="11">D-beta-D-heptose 1-phosphate adenylyltransferase</fullName>
                <ecNumber evidence="11">2.7.7.70</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="11">D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase</fullName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="11" type="primary">hldE</name>
        <name evidence="14" type="ORF">VDA_002939</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 11">Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.</text>
    </comment>
    <comment type="function">
        <text evidence="2 11">Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>ATP + D-glycero-beta-D-manno-heptose 1-phosphate + H(+) = ADP-D-glycero-beta-D-manno-heptose + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:27465"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:59967"/>
            <dbReference type="ChEBI" id="CHEBI:61593"/>
            <dbReference type="EC" id="2.7.7.70"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + D-glycero-beta-D-manno-heptose 7-phosphate = ADP + D-glycero-beta-D-manno-heptose 1,7-bisphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:27473"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:60204"/>
            <dbReference type="ChEBI" id="CHEBI:60208"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.167"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Bacterial outer membrane biogenesis; LPS core biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="11">Nucleotide-sugar biosynthesis; ADP-L-glycero-beta-D-manno-heptose biosynthesis; ADP-L-glycero-beta-D-manno-heptose from D-glycero-beta-D-manno-heptose 7-phosphate: step 1/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="11">Nucleotide-sugar biosynthesis; ADP-L-glycero-beta-D-manno-heptose biosynthesis; ADP-L-glycero-beta-D-manno-heptose from D-glycero-beta-D-manno-heptose 7-phosphate: step 3/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">In the C-terminal section; belongs to the cytidylyltransferase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">In the N-terminal section; belongs to the carbohydrate kinase PfkB family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.167" evidence="11"/>
    <dbReference type="EC" id="2.7.7.70" evidence="11"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301389.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002939"/>
    <dbReference type="EnsemblBacteria" id="EEZ41907">
        <property type="protein sequence ID" value="EEZ41907"/>
        <property type="gene ID" value="VDA_002939"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0615">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2870">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1030724at2"/>
    <dbReference type="UniPathway" id="UPA00356">
        <property type="reaction ID" value="UER00437"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00958"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033785">
        <property type="term" value="F:heptose 7-phosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033786">
        <property type="term" value="F:heptose-1-phosphate adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097171">
        <property type="term" value="P:ADP-L-glycero-beta-D-manno-heptose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009244">
        <property type="term" value="P:lipopolysaccharide core region biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01172">
        <property type="entry name" value="RfaE_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01603">
        <property type="entry name" value="HldE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023030">
        <property type="entry name" value="Bifunc_HldE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011913">
        <property type="entry name" value="RfaE_dom_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011914">
        <property type="entry name" value="RfaE_dom_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01467">
        <property type="entry name" value="CTP_transf_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02198">
        <property type="entry name" value="rfaE_dom_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02199">
        <property type="entry name" value="rfaE_dom_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00583">
        <property type="entry name" value="PFKB_KINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7 11 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="9 11" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="6 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="12">
        <location>
            <begin position="11"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="CTP_transf_like" evidence="13">
        <location>
            <begin position="346"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Ribokinase" evidence="11">
        <location>
            <begin position="1"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Cytidylyltransferase" evidence="11">
        <location>
            <begin position="345"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="265"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="196"/>
            <end position="199"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEZ41907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="477" mass="50625" checksum="6ABFFFBA2B733970" modified="2010-01-19" version="1">MKLTLPNYEQANVVVLGDIMLDRYWYGPTGRISPEAPVPIVKVDQIEDRPGGAANVAMNIAALGGQVNLIGFTGADESAQFLTQKLTSLNVECQFAEVASHPTITKLRVMSRGQQLLRLDFEESFHGVEPTALLTHLDHALAQGVKTVIFSDYAKGALEHVQTMIQRARQAGVAVLVDPKGTDFERYRGATLLTPNLSEFEAVVGKTQSDDELVTKGLELIERFELEALLVTRSEHGMTLLQKGQEPLHMPTQAQEVYDVTGAGDTVISVLAASLSAGKSLADSCKLANAAAGVVVGKLGTSTLSTIELTNAIHGSQDSGFGVVTESQLKAAVAAARARGEKVVMTNGCFDILHAGHVAYLNEAAKLGDRLIVAVNSDASVQALKGPGRPVNPEDRRMAVLAGLGAVDWVVPFSEETPQRLISEVLPTLLVKGGDYKPEEIAGGKEVIAAGGEVKVLNFEDGCSTTEIINAIRGGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z078</accession>
    <name>D0Z078_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">cAMP-dependent Kef-type K+ transport system</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">VDA_002941</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301391.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002941"/>
    <dbReference type="EnsemblBacteria" id="EEZ41909">
        <property type="protein sequence ID" value="EEZ41909"/>
        <property type="gene ID" value="VDA_002941"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1991946at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008076">
        <property type="term" value="C:voltage-gated potassium channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005249">
        <property type="term" value="F:voltage-gated potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013099">
        <property type="entry name" value="K_chnl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028325">
        <property type="entry name" value="VG_K_chnl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027359">
        <property type="entry name" value="Volt_channel_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11537">
        <property type="entry name" value="PTHR11537"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07885">
        <property type="entry name" value="Ion_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0407">Ion channel</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="123"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="187"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="Ion_trans_2" evidence="10">
        <location>
            <begin position="132"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="225"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ41909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="264" mass="30405" checksum="21DAAC99B410C0A4" modified="2010-01-19" version="1">MKYRPQHQHDLHPMSLMAFVLSLISLALVTSMLFIPKQDSVYLIFLGVDTFICLLFWCQLLTDFIRSEEKTNYLKRHWPDFMASIPVIEPFRFARLVQVFRVVRLLRSSKHIMQQLQENRREATIATICLLLTVLITIGSSFILLIEAKDPNANIHSASDALWWVIVTISTVGYGDHYPVTTLGKVLGTMVIVCGVGVFGMISGLVSSIITDPQHQKEQQEKEHRQEWRQMLANQQALLQRLERIEKRMAEQEESDKKNAPDNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z095</accession>
    <name>D0Z095_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Acetolactate synthase</fullName>
            <ecNumber evidence="4 8">2.2.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">VDA_002958</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>H(+) + 2 pyruvate = (2S)-2-acetolactate + CO2</text>
            <dbReference type="Rhea" id="RHEA:25249"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:58476"/>
            <dbReference type="EC" id="2.2.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="8">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
        <text evidence="8">Binds 1 thiamine pyrophosphate per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 1/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 1/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the TPP enzyme family.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.6" evidence="4 8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301424.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002958"/>
    <dbReference type="EnsemblBacteria" id="EEZ41926">
        <property type="protein sequence ID" value="EEZ41926"/>
        <property type="gene ID" value="VDA_002958"/>
    </dbReference>
    <dbReference type="GeneID" id="57340730"/>
    <dbReference type="eggNOG" id="COG0028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="391134at2"/>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00055"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00059"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003984">
        <property type="term" value="F:acetolactate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd02015">
        <property type="entry name" value="TPP_AHAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012846">
        <property type="entry name" value="Acetolactate_synth_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039368">
        <property type="entry name" value="AHAS_TPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012000">
        <property type="entry name" value="Thiamin_PyroP_enz_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012001">
        <property type="entry name" value="Thiamin_PyroP_enz_TPP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000399">
        <property type="entry name" value="TPP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045229">
        <property type="entry name" value="TPP_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme-bd_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18968">
        <property type="entry name" value="PTHR18968"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00205">
        <property type="entry name" value="TPP_enzyme_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02776">
        <property type="entry name" value="TPP_enzyme_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00118">
        <property type="entry name" value="acolac_lg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00187">
        <property type="entry name" value="TPP_ENZYMES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="6 8 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TPP_enzyme_N" evidence="11">
        <location>
            <begin position="5"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_M" evidence="9">
        <location>
            <begin position="197"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_C" evidence="10">
        <location>
            <begin position="394"/>
            <end position="543"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ41926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="574" mass="62973" checksum="E120F99BCA3A2546" modified="2010-01-19" version="1">MEMLSGADMVVRSMIDQGVKHIFGYPGGSVLDIYDALHEKSDIEHVLVRHEQAAVHMADGYARATGEVGVVLVTSGPGATNAITGIATAYMDSIPMVVLSGQVMSSLIGNDAFQECDMVGISRPVVKHSFLVTKPEDIPTIIKKAFYLAATGRPGPVVVDIPKDMLNPQERYPYHYPETIALRSYNPTTNGHKGQIKRGLKALLAAKRPALYVGGGAIMSGCSAQLLELAERLNLPVVSTLMGLGAFPGDHPNSVGMLGMHGTYEANMTMHNSDLIFGVGVRFDDRTTNNLAKYCPNATILHIDIDPSSISKTVNADIPIVGSADVVLELMLKLLNEQQETNDGAELDRWWHDIQGWRDRQCLQYETNSDRIKPQQVIESLYQLTQGNAYVASDVGQHQMFAALYYPFAKPRRWINSGGLGTMGFGLPAAMGVKFALPEEEVICVTGDGSIQMNIQELSTALQYDIPVKIVNLNNRFLGMVKQWQDMIYQGRHSHSYMDSVPDFAAIAEAYGHVGVRITDPKTLDSQLKEALALKDKLVFIDISVDETEHVYPMLVRGGAMNEMWLSKTEKTDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z099</accession>
    <name>D0Z099_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 13">2-isopropylmalate synthase</fullName>
            <ecNumber evidence="6 13">2.3.3.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11 13">Alpha-IPM synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12 13">Alpha-isopropylmalate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">leuA</name>
        <name evidence="15" type="ORF">VDA_002962</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 13">Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>3-methyl-2-oxobutanoate + acetyl-CoA + H2O = (2S)-2-isopropylmalate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21524"/>
            <dbReference type="ChEBI" id="CHEBI:1178"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.3.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 13">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 1/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 13">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.3.13" evidence="6 13"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301429.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002962"/>
    <dbReference type="EnsemblBacteria" id="EEZ41930">
        <property type="protein sequence ID" value="EEZ41930"/>
        <property type="gene ID" value="VDA_002962"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0119">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="840579at2"/>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003852">
        <property type="term" value="F:2-isopropylmalate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01025">
        <property type="entry name" value="LeuA_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013709">
        <property type="entry name" value="2-isopropylmalate_synth_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002034">
        <property type="entry name" value="AIPM/Hcit_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036230">
        <property type="entry name" value="LeuA_allosteric_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005671">
        <property type="entry name" value="LeuA_bact_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08502">
        <property type="entry name" value="LeuA_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00917">
        <property type="entry name" value="LeuA_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110921">
        <property type="entry name" value="SSF110921"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00973">
        <property type="entry name" value="leuA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00815">
        <property type="entry name" value="AIPM_HOMOCIT_SYNTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00816">
        <property type="entry name" value="AIPM_HOMOCIT_SYNTH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50991">
        <property type="entry name" value="PYR_CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="13" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 13" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="8 13" id="KW-0432">Leucine biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 13 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyruvate carboxyltransferase" evidence="14">
        <location>
            <begin position="5"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00018198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEZ41930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="513" mass="56219" checksum="F83456C0724387A8" modified="2010-01-19" version="1">MNDQVIIFDTTLRDGEQALSASLTVKEKLQIAFALERLGVDVIEAGFPVSSPGDFDSVRTIAENIKQSRICALSRAVAKDIDVAAESLKVAEAFRIHTFISTSTIHVQDKLRRSYDDVIEMGVAAVKRARNYTDDVEFSCEDAGRTPIDNLCKMVEAAICAGARTINIPDTVGYTLPSEFGSIIEHLFNRVPNIDKAIISVHCHDDLGMSVANSMAAVQAGARQVECTINGIGERAGNCSLEEIAMIIKTRSDLLGVQTQINHEEIYRTSKMVSQLCNMPVQANKAIVGTNAFSHSSGIHQDGMLKNKNTYEIMTPESIGLKNQSLNLTSRSGRAAVKSHMDQLGYSEQEYNLDTLYQDFLKLADRKGQVFDYDLEALVHFANVREEDDYYKLNYLSVQSGSVMATTSIKLQCGETEKCEAAVGNGPVDALYQCIYRLTGYEIVLDKFDLTAKGEGEDGLGQADIIANYQGRKYHGTGLATDIVEASGQALLHVINSIHRANQIAEIKRSAHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-06-02" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0E2</accession>
    <name>D0Z0E2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">OapA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_003006</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301548.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003006"/>
    <dbReference type="EnsemblBacteria" id="EEZ41973">
        <property type="protein sequence ID" value="EEZ41973"/>
        <property type="gene ID" value="VDA_003006"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3061">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2008670at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042834">
        <property type="term" value="F:peptidoglycan binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007340">
        <property type="entry name" value="Opacity-associatedA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04225">
        <property type="entry name" value="OapA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OapA" evidence="2">
        <location>
            <begin position="198"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="280" mass="30538" checksum="A3BD3A0AACDC05AF" modified="2010-01-19" version="1">MGQANRRLSRKNRTKRDTKDMNALKQRLLDGIAPLTVGWQKLPTFHRRAVTVVGVLMIGAFFLPTSNDLQSDLNDGSSDGRREISLDLGGVVTQPEISTTSSTSDGDKQGTIKLDISATTNRAQDDKAPDDKASGAAKAVKDPNQPHPTGGMVDNGPRPELKPYPSKIYPLDGSAPYMEKVKNAAAQEAKIQASAGPWRSYTVQSGETLANIFRKLSLNDRDAFLMAKVEGSDKPISRIHRGQVLRFRTNSSGEVTDLQITDDGRTVSFALQPTGSYRRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0J0</accession>
    <name>D0Z0J0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative ribosomal protein S6 modification protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_003054</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003054"/>
    <dbReference type="EnsemblBacteria" id="EEZ42021">
        <property type="protein sequence ID" value="EEZ42021"/>
        <property type="gene ID" value="VDA_003054"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0189">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013651">
        <property type="entry name" value="ATP-grasp_RimK-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004666">
        <property type="entry name" value="RpS6_RimK/Lys_biosynth_LsyX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08443">
        <property type="entry name" value="RimK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00768">
        <property type="entry name" value="rimK_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="ATP-grasp" evidence="2">
        <location>
            <begin position="1"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ42021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="187" mass="19739" checksum="28579F7649529E81" modified="2010-01-19" version="1">MPVTGFASKPSDVPDLIKMVGGAPLVIKLLEGTQGIGVVLAETQKAAESVIEAFMGLKANIMVQEYIEEAGGADIRCFVIGDKVIASMKRQGAEGEFRSNLHRGGSASLIRITPEERKTAVAAAKAMGLSVAGVDLLRSNRGPLVMEVNSSPGLEGIEGATGKDIAGMIIEYIEKNVGKSRRHLQHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-02-10" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0J2</accession>
    <name>D0Z0J2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase OrfAB subunit B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003056</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ42023">
        <property type="protein sequence ID" value="EEZ42023"/>
        <property type="gene ID" value="VDA_003056"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2801">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032196">
        <property type="term" value="P:transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038965">
        <property type="entry name" value="InsF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46889:SF1">
        <property type="entry name" value="PTHR46889:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="1">
        <location>
            <begin position="52"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="225" mass="26239" checksum="ED513A78BFC004F2" modified="2010-01-19" version="1">MVTTQGIPLSRYRASKQMKALNLVSCQSPKHRYRKANQEHIAIPNHLDRQFAVTSPNQVWVGDVTYVWAGNRWMYLAVVIDLFSRKPVGWAMSLSPDSRLTGKALMMAYESRHKPKGVMFHSDQDSHYTSSYYRQLLWRCQIKQSLSRRGNCWDNAPMERFFRSLKTEWVPNVGYCSFAEAKHEITRYIIGYYSQLRPHQYNGGLTPNESERLYWLTSNTVASIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0Q6</accession>
    <name>D0Z0Q6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">General secretion pathway protein F</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">VDA_003120</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the type II secretion system inner membrane complex required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 15">Cell inner membrane</location>
            <topology evidence="3 15">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 15">Belongs to the GSP F family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301922.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003120"/>
    <dbReference type="EnsemblBacteria" id="EEZ42087">
        <property type="protein sequence ID" value="EEZ42087"/>
        <property type="gene ID" value="VDA_003120"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1459">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1596769at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.81.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003004">
        <property type="entry name" value="GspF/PilC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011850">
        <property type="entry name" value="T2SS_GspF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001992">
        <property type="entry name" value="T2SS_GspF/T4SS_PilC_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018076">
        <property type="entry name" value="T2SS_GspF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042094">
        <property type="entry name" value="T2SS_GspF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30012">
        <property type="entry name" value="PTHR30012"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00482">
        <property type="entry name" value="T2SSF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00812">
        <property type="entry name" value="BCTERIALGSPF"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02120">
        <property type="entry name" value="GspF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00874">
        <property type="entry name" value="T2SP_F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0106">Calcium</keyword>
    <keyword evidence="7" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="13 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 15 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5 15" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="170"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="224"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="377"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="17">
        <location>
            <begin position="72"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="17">
        <location>
            <begin position="274"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00030750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU003923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EEZ42087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="406" mass="44994" checksum="C5B757D01E16796D" modified="2010-01-19" version="1">MAAFEYKALDSKGRQKKGVMEGDTARQVRQLLREKGMVPLEVTQTQAQSKKGSGPSFHFRRGISTNELALITRQIATLVQASMPLEECLKAVAEQNEKPRLKNILLAVRSRVVEGYTLADSMAEFPHIFDQLFRAMVAAGEKSGHLDAVLNRLADYAENRQQMRSKLQQAMIYPTMLTLIAISVVSFLLATVVPKIVDQFVRTGQPLPTITEVLLAASNFVQHWGLLVLVVIAVVVFGVKYALKKPSFRLKWDRTVLHLPVIGKVARGLSTSRFARTLSICTSSAIPLLDGMKVASDVMTNTYVHQKILEASDKVREGVSLRLSLEQSKLFPPMMLHMIASGERSGELEQMLTRAADNQDRDFESLVNMALGVFEPLLIVAMAGIVMFIVIATLMPIIELNNMVGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0U8</accession>
    <name>D0Z0U8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">HemX-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_003162</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003162"/>
    <dbReference type="EnsemblBacteria" id="EEZ42129">
        <property type="protein sequence ID" value="EEZ42129"/>
        <property type="gene ID" value="VDA_003162"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2959">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007470">
        <property type="entry name" value="HemX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38043">
        <property type="entry name" value="PTHR38043"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04375">
        <property type="entry name" value="HemX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="51"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="379"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="80"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="409"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ42129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="426" mass="46710" checksum="220720C1A188962D" modified="2010-01-19" version="1">MTEKKITNDSAAEKQQAPSGAKAQPTKAAKDTAPKAPKPAPQQKSGGSKTGLIAIALVIALGGGLYYHGHQQSLAQEAQITALQNQLSGLKNSLASNEQSVLSKVNTTLTSTEVALNQQEKSISSLQMALAEMKGRSPNDWLLAEADYLTKMAGRKLWLEHDVNSATVLLEAADHRIAELNDPSLKDLRLALNNDITSLKAVARVDRDGLVLRLTSLEQHVDSLPLANALMPKALEQKAQTVSQSVNDWKVNLMTSLENFSDHFITYRKRDGNVVPLLSPQQDFYLQENIKNKLETAIRAVYREQGEVYKQSLITAQKWAEQYYDMSSPAVQSFVKTLEQLENQNIEAVYPKQLKAQAILTNIISERLRSQVKSLATEESKAEAVKPAASEVKAAPKTEAKVETEVKTEATETQSAPQVVSQENQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0X1</accession>
    <name>D0Z0X1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Glutathione reductase</fullName>
            <ecNumber evidence="13">1.8.1.7</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">VDA_003185</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="8">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.7" evidence="13"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302102.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003185"/>
    <dbReference type="EnsemblBacteria" id="EEZ42152">
        <property type="protein sequence ID" value="EEZ42152"/>
        <property type="gene ID" value="VDA_003185"/>
    </dbReference>
    <dbReference type="GeneID" id="57340581"/>
    <dbReference type="eggNOG" id="COG1249">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="267896at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004362">
        <property type="term" value="F:glutathione-disulfide reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006322">
        <property type="entry name" value="Glutathione_Rdtase_euk/bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012999">
        <property type="entry name" value="Pyr_OxRdtase_I_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42737">
        <property type="entry name" value="PTHR42737"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="SSF55424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01421">
        <property type="entry name" value="gluta_reduc_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00076">
        <property type="entry name" value="PYRIDINE_REDOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 8 10" id="KW-0274">FAD</keyword>
    <keyword evidence="3 10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 10 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6 10" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="12">
        <location>
            <begin position="6"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_dim" evidence="11">
        <location>
            <begin position="340"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="440"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="174"/>
            <end position="181"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="262"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="303"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="9">
        <location>
            <begin position="42"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ42152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="451" mass="48494" checksum="89B9500A116ACB23" modified="2010-01-19" version="1">MAKHFDYICIGGGSGGIASANRAAMYGAKVALIEAKALGGTCVNVGCVPKKVMWHGAQIAEAMHLYAKDYGFDVDMKGLNWGKLVESREAYISRIHTSYETVLGNNKIEVINGFAQFVDAKTVEVDGEHYTADHILIAVGGRPSIPAIPGAVHGIDSNGFFELKEQPKRAAVVGAGYIAVEIAGVLNGLGTDTHLFVRKESPLRSFDPMIIETLTEVMAAEGPTLHTHSVPKEVVKEEDGTVTLYFENGESHNTDILIWAIGREPTTDAINLAAAGVETNNRGFIKVDEFQQTNVEGIYCVGDIMEGGIELTPVAVKAGRQLSERLFNNKPNAKMDYALVPTVVFSHPPIGTIGLTEPEAIAQYGAENVKVYKSGFTAMYTAVTQHRQPCRMKLVCAGEDEKVVGLHGIGFGVDEMIQGFGVAMKMGATKADFDSVVAIHPTGSEEFVTMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z117</accession>
    <name>D0Z117_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ATP synthase gamma chain</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">ATP synthase F1 sector gamma subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">F-ATPase gamma subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">atpG</name>
        <name evidence="10" type="ORF">VDA_003231</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the ATPase gamma chain family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302231.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003231"/>
    <dbReference type="EnsemblBacteria" id="EEZ42198">
        <property type="protein sequence ID" value="EEZ42198"/>
        <property type="gene ID" value="VDA_003231"/>
    </dbReference>
    <dbReference type="GeneID" id="57340362"/>
    <dbReference type="eggNOG" id="COG0224">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1701531at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042777">
        <property type="term" value="P:proton motive force-driven plasma membrane ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12151">
        <property type="entry name" value="F1-ATPase_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00815">
        <property type="entry name" value="ATP_synth_gamma_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035968">
        <property type="entry name" value="ATP_synth_F1_ATPase_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000131">
        <property type="entry name" value="ATP_synth_F1_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023632">
        <property type="entry name" value="ATP_synth_F1_gsu_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11693">
        <property type="entry name" value="PTHR11693"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00231">
        <property type="entry name" value="ATP-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00126">
        <property type="entry name" value="ATPASEGAMMA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52943">
        <property type="entry name" value="SSF52943"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01146">
        <property type="entry name" value="ATPsyn_F1gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00153">
        <property type="entry name" value="ATPASE_GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0139">CF(1)</keyword>
    <keyword evidence="4 9" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ42198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="288" mass="31869" checksum="DE233219A8F09E3D" modified="2010-01-19" version="1">MAGAKEIRNKIGSVKNTQKITKAMEMVAASKMRKTQDAMESSRPYAQTMRKVIGHIALGSLEYQHPYLEEREAKRVGYIIVSTDRGLCGGLNINLFKKAITDIQQWNQQGAEVELALIGAKATAFFNSYGGNVSAQVSGLGDAPTVDELIGTVGVMLKKYDEGQLDRLYLVYNKFVNTMVQDPVIDQLLPLPKSQDEDMQRNHSWDYIYEPEPKLLLDTLLVRYAESQVYQGVVENLACEQAARMVAMKAATDNAGNLIDDLQLVYNKARQTAITQELSEIVSGAAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z130</accession>
    <name>D0Z130_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">50S ribosomal protein L34</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpmH</name>
        <name evidence="6" type="ORF">VDA_003244</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the bacterial ribosomal protein bL34 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302269.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003244"/>
    <dbReference type="EnsemblBacteria" id="EEZ42211">
        <property type="protein sequence ID" value="EEZ42211"/>
        <property type="gene ID" value="VDA_003244"/>
    </dbReference>
    <dbReference type="GeneID" id="57340346"/>
    <dbReference type="eggNOG" id="COG0230">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2069770at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00391">
        <property type="entry name" value="Ribosomal_L34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000271">
        <property type="entry name" value="Ribosomal_L34"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020939">
        <property type="entry name" value="Ribosomal_L34_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14503">
        <property type="entry name" value="PTHR14503"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00468">
        <property type="entry name" value="Ribosomal_L34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01030">
        <property type="entry name" value="rpmH_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00784">
        <property type="entry name" value="RIBOSOMAL_L34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ42211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="45" mass="5253" checksum="5767F89C2A2A99B7" modified="2010-01-19" version="1">MSKRTFQPSVLKRKRTHGFRARMATKNGRAVINARRAKGRKRLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1D3</accession>
    <name>D0Z1D3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Formamidopyrimidine-DNA glycosylase</fullName>
            <shortName evidence="15">Fapy-DNA glycosylase</shortName>
            <ecNumber evidence="15">3.2.2.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">DNA-(apurinic or apyrimidinic site) lyase MutM</fullName>
            <shortName evidence="15">AP lyase MutM</shortName>
            <ecNumber evidence="15">4.2.99.18</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">mutM</name>
        <name evidence="15" type="synonym">fpg</name>
        <name evidence="19" type="ORF">VDA_003347</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14 15">
            <text>2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-monophospho-2'-deoxyribonucleoside-DNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66592"/>
            <dbReference type="Rhea" id="RHEA-COMP:13180"/>
            <dbReference type="Rhea" id="RHEA-COMP:16897"/>
            <dbReference type="Rhea" id="RHEA-COMP:17067"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:136412"/>
            <dbReference type="ChEBI" id="CHEBI:157695"/>
            <dbReference type="ChEBI" id="CHEBI:167181"/>
            <dbReference type="EC" id="4.2.99.18"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 15">
            <text>Hydrolysis of DNA containing ring-opened 7-methylguanine residues, releasing 2,6-diamino-4-hydroxy-5-(N-methyl)formamidopyrimidine.</text>
            <dbReference type="EC" id="3.2.2.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="15">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 15">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the FPG family.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.23" evidence="15"/>
    <dbReference type="EC" id="4.2.99.18" evidence="15"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302542.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003347"/>
    <dbReference type="EnsemblBacteria" id="EEZ42314">
        <property type="protein sequence ID" value="EEZ42314"/>
        <property type="gene ID" value="VDA_003347"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0266">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1162346at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140078">
        <property type="term" value="F:class I DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008534">
        <property type="term" value="F:oxidized purine nucleobase lesion DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00103">
        <property type="entry name" value="Fapy_DNA_glycosyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015886">
        <property type="entry name" value="DNA_glyclase/AP_lyase_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015887">
        <property type="entry name" value="DNA_glyclase_Znf_dom_DNA_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020629">
        <property type="entry name" value="Formamido-pyr_DNA_Glyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012319">
        <property type="entry name" value="FPG_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035937">
        <property type="entry name" value="MutM-like_N-ter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010979">
        <property type="entry name" value="Ribosomal_S13-like_H2TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000214">
        <property type="entry name" value="Znf_DNA_glyclase/AP_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010663">
        <property type="entry name" value="Znf_FPG/IleRS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01149">
        <property type="entry name" value="Fapy_DNA_glyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06831">
        <property type="entry name" value="H2TH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06827">
        <property type="entry name" value="zf-FPG_IleRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00898">
        <property type="entry name" value="Fapy_DNA_glyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01232">
        <property type="entry name" value="H2TH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46946">
        <property type="entry name" value="SSF46946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81624">
        <property type="entry name" value="SSF81624"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00577">
        <property type="entry name" value="fpg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51068">
        <property type="entry name" value="FPG_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01242">
        <property type="entry name" value="ZF_FPG_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51066">
        <property type="entry name" value="ZF_FPG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 15" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10 15" id="KW-0234">DNA repair</keyword>
    <keyword evidence="9 15" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="13 15 19" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7 15 19" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11 15" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 15" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 15" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 15 16" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FPG_CAT" evidence="18">
        <location>
            <begin position="2"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="FPG-type" evidence="17">
        <location>
            <begin position="235"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with DNA" evidence="15">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="15">
        <location>
            <position position="3"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for beta-elimination activity" evidence="15">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for delta-elimination activity" evidence="15">
        <location>
            <position position="259"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>DNA</name>
            <dbReference type="ChEBI" id="CHEBI:16991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>DNA</name>
            <dbReference type="ChEBI" id="CHEBI:16991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>DNA</name>
            <dbReference type="ChEBI" id="CHEBI:16991"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00024490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EEZ42314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="269" mass="29588" checksum="EBC1C622138DA908" modified="2010-01-19" version="1">MPELPEVEVTRLGITPHVLHQTVTDIVIRNGRLRWPIPDDINQIKQQPITKVRRRAKYLLLDTPVGSAIVHLGMSGSLRVLPAGTAPEKHDHVDLVLSSGEILRYNDPRRFGAWLWQPVDTKHHVLAKLGPEPLTDAFTADYLQQKAKGKRTAIKQFIMDNHIVVGVGNIYANESLFSAGIHPQKAAGEVTPQALTVLVDEIKAVLAFAIQQGGTTLKDFKNADGKPGYFAQELQVYGKGGLPCPKCGTELAEVKIGQRATVYCPQCQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1D9</accession>
    <name>D0Z1D9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">3-deoxy-D-manno-octulosonic acid transferase</fullName>
            <shortName evidence="9">Kdo transferase</shortName>
            <ecNumber evidence="3 9">2.4.99.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 9">Lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">VDA_003353</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>CMP-3-deoxy-beta-D-manno-octulosonate + lipid IVA (E. coli) = alpha-Kdo-(2-&gt;6)-lipid IVA + CMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:28066"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58603"/>
            <dbReference type="ChEBI" id="CHEBI:60364"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="ChEBI" id="CHEBI:85987"/>
            <dbReference type="EC" id="2.4.99.12"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Bacterial outer membrane biogenesis; LPS core biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the glycosyltransferase group 1 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.99.12" evidence="3 9"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302555.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003353"/>
    <dbReference type="EnsemblBacteria" id="EEZ42320">
        <property type="protein sequence ID" value="EEZ42320"/>
        <property type="gene ID" value="VDA_003353"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1519">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1163086at2"/>
    <dbReference type="UniPathway" id="UPA00958"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043842">
        <property type="term" value="F:Kdo transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009244">
        <property type="term" value="P:lipopolysaccharide core region biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11720">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007507">
        <property type="entry name" value="Glycos_transf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038107">
        <property type="entry name" value="Glycos_transf_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039901">
        <property type="entry name" value="Kdotransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42755">
        <property type="entry name" value="PTHR42755"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04413">
        <property type="entry name" value="Glycos_transf_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0448">Lipopolysaccharide biosynthesis</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycos_transf_N" evidence="11">
        <location>
            <begin position="35"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="10">
        <location>
            <begin position="246"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="8">
        <location>
            <position position="130"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="8">
        <location>
            <position position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR639901-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR639901-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF04413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ42320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="423" mass="46955" checksum="9C2FC44489C282E5" modified="2010-01-19" version="1">MLFRLLYSLLLACAAPFLLYSLYKKKPGKPQIGSRWREHFGITPKINATAPIWLHTVSVGESIAAIPVIKALKQAYPNKTIIVTTTTTTGAEQIAKLGNLVEHRYMPIDFSCCVQRFINTIEPCALLIMETELWPNTLATVATANIPITVINARLSERSAQRYQQFSWLFAHIGPYLNHVLCLHQDDANRFIQLGIDRDKVAVTGSVKFDIEINSQVRQQAQQLRQLLGMERPIWIAASTHKGEDEQLLAAFKTIKQNIPNALLILVPRHPERFDSVFTLCQQYGFVTQRRTQDHNGLLNSDVYLGDTMGEMLTLMGAADVVFMAGSLIGDAVGGHNMLEPAALAKPILTGPSFYNFTDISEQLEHANGLIICQNSEEISHNICQLLSQKDLQQQMGQAALHVVKSNQGAVANTVAAIAPYCH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1G1</accession>
    <name>D0Z1G1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Triosephosphate isomerase</fullName>
            <shortName evidence="4">TIM</shortName>
            <shortName evidence="4">TPI</shortName>
            <ecNumber evidence="4 5">5.3.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Triose-phosphate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">tpiA</name>
        <name evidence="6" type="ORF">VDA_003375</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 5">
            <text>D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:18585"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="5.3.1.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4 5">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 5">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate from glycerone phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4 5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the triosephosphate isomerase family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.1" evidence="4 5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302597.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003375"/>
    <dbReference type="EnsemblBacteria" id="EEZ42342">
        <property type="protein sequence ID" value="EEZ42342"/>
        <property type="gene ID" value="VDA_003375"/>
    </dbReference>
    <dbReference type="GeneID" id="57340175"/>
    <dbReference type="eggNOG" id="COG0149">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1266295at2"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00189"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004807">
        <property type="term" value="F:triose-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00311">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00147_B">
        <property type="entry name" value="TIM_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035990">
        <property type="entry name" value="TIM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022896">
        <property type="entry name" value="TrioseP_Isoase_bac/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000652">
        <property type="entry name" value="Triosephosphate_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020861">
        <property type="entry name" value="Triosephosphate_isomerase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21139">
        <property type="entry name" value="PTHR21139"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00121">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51351">
        <property type="entry name" value="SSF51351"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00419">
        <property type="entry name" value="tim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00171">
        <property type="entry name" value="TIM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51440">
        <property type="entry name" value="TIM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 4 5" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="2 4 5" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="3 4 5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="9"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="235"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="active site" description="Electrophile" evidence="4">
        <location>
            <position position="97"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="169"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="214"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ42342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="256" mass="26978" checksum="A44A71E34F172C0F" modified="2010-01-19" version="1">MRHPVVMGNWKLNGSKEMVSNLIKGLDAELNGVEGVDVAIAPPVMFLDLAEQLISKANNKIILGAQNVDIHESGAFTGDISPAMLKEFGATHIIIGHSERRDYHNESDEFVAQKFAFLKEHGLTPVLCIGESEAQNEAGETVAVCARQIDAVIKTQGVDALNGAIIAYEPIWAIGTGKAATAEDAQRIHAAIRAHIAEQSEEVAKNVVIQYGGSVKPENAAAYFAQPDIDGALVGGAALDAASFAAIAKAAAEAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1G3</accession>
    <name>D0Z1G3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ferredoxin--NADP(+) reductase</fullName>
            <ecNumber evidence="4">1.18.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_003377</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H(+) + NADP(+) + 2 reduced [2Fe-2S]-[ferredoxin] = NADPH + 2 oxidized [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:20125"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.18.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ferredoxin--NADP reductase type 1 family.</text>
    </comment>
    <dbReference type="EC" id="1.18.1.2" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302602.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003377"/>
    <dbReference type="EnsemblBacteria" id="EEZ42344">
        <property type="protein sequence ID" value="EEZ42344"/>
        <property type="gene ID" value="VDA_003377"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1018">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="707164at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004324">
        <property type="term" value="F:ferredoxin-NADP+ reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06195">
        <property type="entry name" value="FNR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033892">
        <property type="entry name" value="FNR_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="6">
        <location>
            <begin position="2"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ42344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="246" mass="27665" checksum="06CE89877716A837" modified="2010-01-19" version="1">MANWVEATVIKNHHWNDDLFSLTLDAPVETFTAGQFTKLALDIDGTRVQRAYSYVNSPNAPLEIYATRVADGLLSPKLHALKEGDKVFITPQANGFFTLDEVPEGDILWLFATGTAIGPYLSILGEPTVWQRFNTIVLVHAVRYQADLSYQQTVAKFQADHPNQLYYQPFVSRESIANTLAGRIPQAISNGSLEQVLELSLIPEHSQIMLCGNPQMVRDTREALEGKGFKKNLRRKPGQITMENYW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1I5</accession>
    <name>D0Z1I5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Argininosuccinate lyase</fullName>
            <shortName evidence="8">ASAL</shortName>
            <ecNumber evidence="4 8">4.3.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Arginosuccinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">argH</name>
        <name evidence="11" type="ORF">VDA_003399</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>2-(N(omega)-L-arginino)succinate = fumarate + L-arginine</text>
            <dbReference type="Rhea" id="RHEA:24020"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:57472"/>
            <dbReference type="EC" id="4.3.2.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8 9">Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.1" evidence="4 8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302645.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003399"/>
    <dbReference type="EnsemblBacteria" id="EEZ42366">
        <property type="protein sequence ID" value="EEZ42366"/>
        <property type="gene ID" value="VDA_003399"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0165">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1246">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="751464at2"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00114"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004056">
        <property type="term" value="F:argininosuccinate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042450">
        <property type="term" value="P:arginine biosynthetic process via ornithine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01359">
        <property type="entry name" value="Argininosuccinate_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00006">
        <property type="entry name" value="Arg_succ_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029419">
        <property type="entry name" value="Arg_succ_lyase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009049">
        <property type="entry name" value="Argininosuccinate_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011244">
        <property type="entry name" value="ASAL_AGS_AcTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43814">
        <property type="entry name" value="PTHR43814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14698">
        <property type="entry name" value="ASL_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036456">
        <property type="entry name" value="ASAL_AGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="SSF48557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00838">
        <property type="entry name" value="argH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9 11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5 8 9" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="8 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 9 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="10">
        <location>
            <begin position="464"/>
            <end position="616"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR036456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ42366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="625" mass="69503" checksum="C31A2EF2138243E7" modified="2010-01-19" version="1">MALWGGRFSQAADIRFKQFNDSLRFDYRLAEQDIIGSIAWSKALRQVGVLGEQEQLDLELALNEIKLAVMENPAQILQSDAEDIHSWVEQQLIAKVGDLGKKLHTGRSRNDQVATDLKLWCRQQGQQLLLMLDKLQNQLVTVARAHQATVLPGYTHLQRAQPVTFSHWCLAYVEMFERDYSRLHDALARLDTCPLGSGALAGTAYPIDREQLAHNLGFSRATRNSLDSVSDRDHVMELLSTASISMLHLSRMAEDLIFYNSGESNFIELSDTVTSGSSLMPQKKNPDALELIRGKCGRVYGAMAGMMMTVKALPLAYNKDMQEDKEGLFDALDSWHECMEMAALCFEGIKINQERTLEAAMQGYSNATELADYLVAKGIPFREAHHIVGVAVVMAIDKGCALEALSLEELQSLSPVISEDVYPILTIDSCLEKRCALGGVAPNQVDYAIGQAEKRLEQRYSPSVKVRGARLTDLDAIEGMVVYWAGLGENLPRNRNELVRDIGSFAVAEHHGVVTGCASLYVYDSGLAEIRSLGVEAGWQQQGQGKAIVDYLIEKAKQMAISKVFVLTRVPEFFMKQAFIPTSKSLLPEKVMKDCDRCPRQHACDEVALEMRLDQSQKIPTINVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1M9</accession>
    <name>D0Z1M9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">30S ribosomal protein S19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpsS</name>
        <name evidence="7" type="ORF">VDA_003443</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uS19 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302795.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003443"/>
    <dbReference type="EnsemblBacteria" id="EEZ42410">
        <property type="protein sequence ID" value="EEZ42410"/>
        <property type="gene ID" value="VDA_003443"/>
    </dbReference>
    <dbReference type="GeneID" id="61231774"/>
    <dbReference type="eggNOG" id="COG0185">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1893906at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00531">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020934">
        <property type="entry name" value="Ribosomal_S15/S19_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002222">
        <property type="entry name" value="Ribosomal_S19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005732">
        <property type="entry name" value="Ribosomal_S19_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023575">
        <property type="entry name" value="Ribosomal_S19_S15_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11880">
        <property type="entry name" value="PTHR11880"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00203">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002144">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00975">
        <property type="entry name" value="RIBOSOMALS19"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54570">
        <property type="entry name" value="SSF54570"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01050">
        <property type="entry name" value="rpsS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00323">
        <property type="entry name" value="RIBOSOMAL_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ42410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="92" mass="10454" checksum="F3947D9197F02950" modified="2010-01-19" version="1">MPRSLKKGPFIDLHLLKKVEKALESGDKKPVKTWSRRSMIIPQMIGLTIAVHNGRQHVPVFVSEEMIGHKLGEFAPTRTYRGHAADKKAKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1T6</accession>
    <name>D0Z1T6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MSHA pilin protein MshA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303618.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003500"/>
    <dbReference type="EnsemblBacteria" id="EEZ42467">
        <property type="protein sequence ID" value="EEZ42467"/>
        <property type="gene ID" value="VDA_003500"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2165">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1986406at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="161" mass="16528" checksum="6F57F8F8D6E41486" modified="2010-01-19" version="1">MKRQGGFTLIELVVVIVILGILAVTAAPKFMNLQTDARNASLQGLKGAIQGAAGIVYGKAAINGIEAKNTATDLDVDGKTIKTIYGYPVATSAALSAVVQGLDNNDEWLPVNNSQGGEAAGDSISYTFANQEKNASTTVCSVTYTAAQSGAAATVKVNDCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1X2</accession>
    <name>D0Z1X2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Ubiquinol cytochrome C oxidoreductase cytochrome C1 subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_003536</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303728.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003536"/>
    <dbReference type="EnsemblBacteria" id="EEZ42503">
        <property type="protein sequence ID" value="EEZ42503"/>
        <property type="gene ID" value="VDA_003536"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2857">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1426747at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002326">
        <property type="entry name" value="Cyt_c1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10266">
        <property type="entry name" value="PTHR10266"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02167">
        <property type="entry name" value="Cytochrom_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 6" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019322" evidence="8">
        <location>
            <begin position="19"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="218"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="9">
        <location>
            <begin position="36"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ42503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="245" mass="27922" checksum="1C828D1C466A292E" modified="2010-01-19" version="1">MKKWLIVFFAFIPSLVLAAGSNVSLDQPNNDLRDKASLQKGAKLFVNYCLACHSMQYQRYERVANDLAIPPDLMMENLVFDENAKIGDLMTNSISPDYAAASFGAPAPDLTMVARVRGTDWLYTYLRSFYADPSRPFGVNNLVFPSVGMPHVLEELQGVPNKIYETKLIDGEEVQEFVGIESDGTGELNQEEYDQAIRDLVNFLEYSGEPMKLERQRLGWWVMGFIAIFFILAILLKKEYWRDVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1X3</accession>
    <name>D0Z1X3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Stringent starvation protein A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_003537</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GST superfamily. HSP26 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303729.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003537"/>
    <dbReference type="EnsemblBacteria" id="EEZ42504">
        <property type="protein sequence ID" value="EEZ42504"/>
        <property type="gene ID" value="VDA_003537"/>
    </dbReference>
    <dbReference type="GeneID" id="57339986"/>
    <dbReference type="eggNOG" id="COG0625">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1997747at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03186">
        <property type="entry name" value="GST_C_SspA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03059">
        <property type="entry name" value="GST_N_SspA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034342">
        <property type="entry name" value="SspA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034341">
        <property type="entry name" value="SspA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="SSF47616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="2">
        <location>
            <begin position="9"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="3">
        <location>
            <begin position="61"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ42504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="212" mass="24347" checksum="17DADAED3836FF14" modified="2010-01-19" version="1">MAVAANKRSVMTLYSDASDIYSHQVRIVLAEKGVSFETELVEPNNLPEDLLDLNPYHSVPTLVDRELVLYQANIIMEYLDERFPHPPLMPVYPVARGNSRLMMYRVERNWYTLAEKVNNGTLDDADKARKQLREELLALAPVFAEYPYFMSDEFSLVDCYLAPLLWRLPTMGIELSGPGSKEVKAYMTRVFERDSFLASLTEAEREMRLAGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z208</accession>
    <name>D0Z208_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fucose 4-O-acetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001969</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299049.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001969"/>
    <dbReference type="EnsemblBacteria" id="EEZ40937">
        <property type="protein sequence ID" value="EEZ40937"/>
        <property type="gene ID" value="VDA_001969"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1835">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1979131at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002656">
        <property type="entry name" value="Acyl_transf_3_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01757">
        <property type="entry name" value="Acyl_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="159"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="186"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="216"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="244"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="284"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="309"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl_transf_3" evidence="2">
        <location>
            <begin position="7"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="341" mass="39073" checksum="F0DD98AE25074751" modified="2010-01-19" version="1">MNENRIPSLELGRVIAIFAVVIIHSQAFNTLPLINGEPWLGYLLNQSSRFAVPLFFLISGYLIAPKLIASPQQTACSYSIPLLKVWLIWSIIYLIAPFNLNTVMQESYLQERMGYWQYLSENPINSLFEGGLVHLWFIPALICAVILIAFFIRFNKIEWLLPFALLLFVYGLLAGSYQPYTELDSIIFTRNGPFFATLMVGLGFEYRRQKWQLSNTIALLLFIGGMSLHLTEAFMLSLLPDGLFNIHDFLLGTPLWGLGIFILLLNHPNIGNTQWVRYCAKHTLGIYVLHLLLIIYFMNISMMLNLNPWVSNILIIPATYCISLIIISLIDKTRLKHILLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z210</accession>
    <name>D0Z210_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001971</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299053.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001971"/>
    <dbReference type="EnsemblBacteria" id="EEZ40939">
        <property type="protein sequence ID" value="EEZ40939"/>
        <property type="gene ID" value="VDA_001971"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502Z7NT">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="325408at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="240"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="264"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="454" mass="53478" checksum="EDC2EB96880A04FB" modified="2010-01-19" version="1">MITVDKKDGHKLKISHVIQETTNRQLDIYIFVPGELGLTSNIISDEEFYHNAIHGKRTYYSDVNHLPLVHSRLASRGKLSIEQYRLSLSLYAYQYALALEKETHNLLENKESVTLDDVSELSELTIRILKRLRRNVPTDKKLLKYYENIDNYLSWFTEQRCLAMVAHLPRGNEYPEIKELLLDICASEEQHRIKHKYNSERAMQDQTRMSNKMRLLRRLIEYPVTMKEKTIELGKNTRKIVTGAAAGIVMIFVTLMMIKARGVLGDITASFILVLSLIYAIREVFKDDLKKMLWRWLRKGRARWRKQFFDANTDHLIGRQFEWMEYISYDKLPESIRKTRKHKVSNREETILHYKSTTRMSPTKFLSGYEQTRESIILDLRVVASLMEKGSQRIYQLKDGQVTKESVEKRHLINLITKETDEDNTVRIQRWKIIMNRSKIVDIEPVEVALPVTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z223</accession>
    <name>D0Z223_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative sodium/dicarboxylate symporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_001872</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298851.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001872"/>
    <dbReference type="EnsemblBacteria" id="EEZ40840">
        <property type="protein sequence ID" value="EEZ40840"/>
        <property type="gene ID" value="VDA_001872"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1823">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="781228at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001991">
        <property type="entry name" value="Na-dicarboxylate_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036458">
        <property type="entry name" value="Na:dicarbo_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42865">
        <property type="entry name" value="PTHR42865"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00375">
        <property type="entry name" value="SDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118215">
        <property type="entry name" value="SSF118215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="5"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="32"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="70"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="104"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="184"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="223"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="255"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="335"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="369"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="393"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="464" mass="48675" checksum="EDEA43E70ED68E9B" modified="2010-01-19" version="1">MIYPIVNLIIFALLIALLYQQQRAEKTLSRRVFISLGLGVIFGACLQFVYGSGSEAINQTLNYVNIVGAGYVSLLKMIIMPLIMVSIIGAIIKVKDSGSLGKISGLSIGILLATTAASALIGILVTHLFGLSADSIVQGAREIARGEALQTRLTSVESLSFADMVISFFPSNPFADLAGARPTSTIAVVIFSAFIGVAGLTVIRTQPELGASFEKFIHVVQEVVRALVRMVLNLTPYGVLALMSKVVAGSNYHDILNLISFVAASYVGLALILVMHLVLVSSVGVNPIRYIKKILPVLTFAFTSRSSAGTIPLNIETQVKQLGNSDGVANFSASFGATMGQNGCAGLYPAMLAVMIAPTVGINPLDPSFMLTLIAVVTVSSFGIAGVGGGATFAALIVLSTLNMPVALAGLLISIEPLIDMGRTAINVSGSMTAGTITSRLLGQYDEKVFQQDEETDSSPTHLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z233</accession>
    <name>D0Z233_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001882</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40850">
        <property type="protein sequence ID" value="EEZ40850"/>
        <property type="gene ID" value="VDA_001882"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="308" mass="34610" checksum="9D4E344C8A68E986" modified="2010-01-19" version="1">MYVASSISSIWNFHRENISCEGVMKRYALLYDHVIFNRRGVGIGPGEMASSLGECVSMLINSGETLSDRKSLGKNKAFCNIFVDCWDLVSDVNQFESDVHTVVDESVNNRIGDFCHQEIRRINGLDDDSYAYNIDDVKELYGDLSTDLGINQLLLREGVELVPSYAPIVGRALSNEYSHQGIECHNLFNSDILVPDFDALSWDEIIDLRSDKYIHAFRKVVFDLARSNPDVNEALVNKVQSDLWKLVSESKPNILKTFLTGFLGNLPSPTILNPIGIGSLIKDTYKENKLNNNYGHVFFIQGIRGSES</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z255</accession>
    <name>D0Z255_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative NADH oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001791</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298708.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001791"/>
    <dbReference type="EnsemblBacteria" id="EEZ40759">
        <property type="protein sequence ID" value="EEZ40759"/>
        <property type="gene ID" value="VDA_001791"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0446">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0607">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1149616at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="SSF55424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="3">
        <location>
            <begin position="466"/>
            <end position="550"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="550" mass="60147" checksum="F3FC11F606B3EC59" modified="2010-01-19" version="1">MTKIVIIGGVAGGASAAARARRLSEDAEIIIFERGQYISFANCGLPYHIGGDIPQRQNLLLQTPESFLARFNVDVRVMNEVTTIDRQAKCVTVKNLIDGTSYQESYDFLLLSPGASPIIPPIEGIDNPLTHSLRNIPDMDRILATLDNHKPTHATVVGGGFIGLEMVEAFHQRGIATTLLEMAPQVMTPVDPEMAGFVHQEIRDKGIDLRLNTALSAIQYHEKTQSLTLSLSNGEDLETGIVIMAIGVRPDIELAKQAGLKIGELGGIWVDETLQTSDPSIFAVGDAVEEKDFVTGKQCLVPLAGPANRQGRMAADNMLGRREHYQGTQGTAICKVFELAVASTGKNEKQLQQQGMAYQKVYVHTASHASYYPGAETVSLKLLFETTSGKILGAQAVGKDGIDKRIDILAVAQRAGMTVEQLQHVELTYAPPYGSAKDVINQAAFVASNIIKGDATPIHYNELEQLTDNQILLDVRNPGELKNMGFIKGAINIPLDQLRHRMNELPKEKEIIIYCAVGLRGNVAYRQLVNNGYKARNLMGGYRTWKFAQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z293</accession>
    <name>D0Z293_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000544</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0145 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39524">
        <property type="protein sequence ID" value="EEZ39524"/>
        <property type="gene ID" value="VDA_000544"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0393">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002765">
        <property type="entry name" value="UPF0145"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035439">
        <property type="entry name" value="UPF0145_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01906">
        <property type="entry name" value="YbjQ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117782">
        <property type="entry name" value="SSF117782"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="54" mass="5824" checksum="D73C8CBDEBFD9012" modified="2010-01-19" version="1">MYNEARSISVERMLDEARNLGADAVVGVRFTTSSVTEGASEVMAFGTAVTLQKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2A0</accession>
    <name>D0Z2A0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_000551</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000551"/>
    <dbReference type="EnsemblBacteria" id="EEZ39531">
        <property type="protein sequence ID" value="EEZ39531"/>
        <property type="gene ID" value="VDA_000551"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="110"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="170"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="200"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="242"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="283"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="312"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="347"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="370"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="415"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="496"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="14"/>
            <end position="516"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="521" mass="57458" checksum="29247CEB93B57A55" modified="2010-01-19" version="1">MNNREGWLSYEVYLLLCVCLAQIITSADNITTALSIKEIMLFFDVNLSTGQIITAFYSVICASLMIISGIFGYFLNWKKIFQLGLCFTFLGEFFAITSHHLLSFVGLSRVFFGLGASLILPACVSLLSTIIRKKNRVLAFSIWGTSVAVVIALFPLLLNALHIYWEWRSGYIILAILSLVVLGLSCKMPEPDFIKSNLKINLSEVILVFVTLMLFLLAIVLIPKFGFITPSLSIGFYLFDYISIPLILFLTSITTFFIYLNIKNENNSIIPQSFYTLTSLCGFYMLALLYVIYGGVLFVIVSYISLGQYPSITLALSTTIFAISMFISSVVAATVLKDKTSQELNTMGLTIITISLFSLAFVMQPKIPSYYFYIALAPIGIGCGFLATKINLVINCSVGIKFSGQSSGAQASAKNIGYVLGVISFGMLLTYATKYEFVDVIGNNTMFLNIDTLDKSIVNGINFMGNEQLMDYFDKALISYNKPELMVINNVIKTKAVSIVLLVGSVLTLLSIPIGNKVASC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2A3</accession>
    <name>D0Z2A3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="12">3-ketoacyl-CoA thiolase</fullName>
            <ecNumber evidence="12">2.3.1.16</ecNumber>
            <ecNumber evidence="12">2.3.1.9</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">VDA_000554</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.16" evidence="12"/>
    <dbReference type="EC" id="2.3.1.9" evidence="12"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304707.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000554"/>
    <dbReference type="EnsemblBacteria" id="EEZ39534">
        <property type="protein sequence ID" value="EEZ39534"/>
        <property type="gene ID" value="VDA_000554"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0183">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="550338at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003985">
        <property type="term" value="F:acetyl-CoA C-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012805">
        <property type="entry name" value="FadA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020615">
        <property type="entry name" value="Thiolase_acyl_enz_int_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020610">
        <property type="entry name" value="Thiolase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020613">
        <property type="entry name" value="Thiolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02445">
        <property type="entry name" value="fadA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00098">
        <property type="entry name" value="THIOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00737">
        <property type="entry name" value="THIOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00099">
        <property type="entry name" value="THIOLASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9 12" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase_N" evidence="10">
        <location>
            <begin position="4"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase_C" evidence="11">
        <location>
            <begin position="262"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="8">
        <location>
            <position position="91"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="343"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000429-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ39534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="387" mass="41220" checksum="A7D172841D2E1A74" modified="2010-01-19" version="1">MKNVVIVDAVRTPMGRSKNGVFRHVRADDLSAELMKSVFKRNPQLAPTMVDDIIWGCVQQTEEQGLNVARNAALIADIPVEVPATTVNRLCGSSMDALHIAACAIKAEDADMILVGGVEHMGHVPMTKGINMNPSNDKTLAQASAMMGLTAEALGKIHKCTREEQDALGARSHRLAHQATLEGLFDNEIVPVMGHDENGIPFLVKHDEVIRPETTEETLAQLRPVFDPVNGTVTAGTSSALSDGASCLVVMSEEKALALGIKPRAKIISMATAGVPAAIMGYGPVPATSKALAKAQLTIHDMDYVEINEAFAAQSIPCLKDLDLWDVRDDKVNLHGGAIALGHPLGCSGARLIATLLNILEQKDGHYGLATMCIGMGQGIATVIERY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2A7</accession>
    <name>D0Z2A7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycerophosphoryl diester phosphodiesterase</fullName>
            <ecNumber evidence="2">3.1.4.46</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000558</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.4.46" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304720.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000558"/>
    <dbReference type="EnsemblBacteria" id="EEZ39538">
        <property type="protein sequence ID" value="EEZ39538"/>
        <property type="gene ID" value="VDA_000558"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0584">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1542724at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008889">
        <property type="term" value="F:glycerophosphodiester phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030395">
        <property type="entry name" value="GP_PDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03009">
        <property type="entry name" value="GDPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="SSF51695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51704">
        <property type="entry name" value="GP_PDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GP-PDE" evidence="1">
        <location>
            <begin position="1"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="247" mass="28103" checksum="779E15B3BEDDF25D" modified="2010-01-19" version="1">MITGHRGAKAIAPENTLISFSIAAHCGAKWIETDTQLSADLVPVIYHDKNINRCTNGSGIVRKLTVDELKKFDAGSWFDPQFSEETIPTLEELLICCDHNNLNLNLEVKVHDEDEAELQVEKTIDVIKAHGFPIEKLILSSFSYRAVKHFKAYWPEVRRGLIIEEWVPQIDRLDEELELFSIHLDHHLLTESLASEIKAAGKELHIWTMNDLNSVMKFRRWGVDNIITDNPGDLIPIDSAFDLGYSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2B1</accession>
    <name>D0Z2B1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Site-specific DNA-methyltransferase (adenine-specific)</fullName>
            <ecNumber evidence="3">2.1.1.72</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_000562</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:15197"/>
            <dbReference type="Rhea" id="RHEA-COMP:12418"/>
            <dbReference type="Rhea" id="RHEA-COMP:12419"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90615"/>
            <dbReference type="ChEBI" id="CHEBI:90616"/>
            <dbReference type="EC" id="2.1.1.72"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the N(4)/N(6)-methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.72" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000562"/>
    <dbReference type="EnsemblBacteria" id="EEZ39542">
        <property type="protein sequence ID" value="EEZ39542"/>
        <property type="gene ID" value="VDA_000562"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0863">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1487464at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002941">
        <property type="entry name" value="DNA_methylase_N4/N6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002295">
        <property type="entry name" value="N4/N6-MTase_EcoPI_Mod-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01555">
        <property type="entry name" value="N6_N4_Mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00506">
        <property type="entry name" value="D21N6MTFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N6_N4_Mtase" evidence="6">
        <location>
            <begin position="25"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="224" mass="26194" checksum="2B764E5358E07128" modified="2010-01-19" version="1">MLITTNHVYKSDALSWLKEIQDQSIDLVITDPPYESLEKHRAVGTTTRLKQSKGSSNDWFRILPNDQFEPLLQEIYRVLKKNSHFYLFCDQETMFIVKPIAEKIGFKFWKPIVWDKCAIGMGYHYRSRYEFILFFEKGKRKLNDLSVPDVLEFKRVWRGYPTEKPVELLKTLIAQSSEPNDIVIDPFFGSGSTLVAASQLQRYYIGCDVSDNAHQHFSQRISEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2C8</accession>
    <name>D0Z2C8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">VgrG protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000579</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the VgrG protein family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304759.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000579"/>
    <dbReference type="EnsemblBacteria" id="EEZ39559">
        <property type="protein sequence ID" value="EEZ39559"/>
        <property type="gene ID" value="VDA_000579"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3501">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1880900at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006531">
        <property type="entry name" value="Gp5/Vgr_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017847">
        <property type="entry name" value="T6SS_RhsGE_Vgr_subset"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006533">
        <property type="entry name" value="T6SS_Vgr_RhsGE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037026">
        <property type="entry name" value="Vgr_OB-fold_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04717">
        <property type="entry name" value="Phage_base_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01646">
        <property type="entry name" value="vgr_GE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03361">
        <property type="entry name" value="VI_Rhs_Vgr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phage_base_V" evidence="2">
        <location>
            <begin position="384"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="673" mass="74952" checksum="F6811FDFF9DF7573" modified="2010-01-19" version="1">MASGLQFTFTVEGLDASTFAVTEFRGSDGLSLPFSFSIDLASRNPSLSPNDTVDRNCSLSVWREGELKQQWFGIVAGFSQGDTGHHHTLYQVQMIPPIGRLALRHNSRIFQTQTVPEIISILLQEMNVQDYAFALARQYPQREYCVQYRETDLAFLQRIAAEEGIFFSFSHEGNKNTVLFTDDTQNVAMLPEPVAYNGLSGGTSPLPFVRQFKRMAQIRPSSAQLKDYSFKNPAYSFLLTEQAKEADYQQAIYEHYDYPGRYKSDESGKPFTLFRLESLRRDAETAQAKSNLETLLPGSKFVLQDHNDDACNRDWLLVEIKHHGTQPQALEEAGGHGVTTYNNEFMVIPGHKPWRPPFNAKPRVDGPQIARVVGPDSEEIYCDEFGRVKIQFPWDRYSNNDDNASCWVRVSQGWAGTQYGMVALPRVGHEVIVSFFEGDPDQPIITGRTYNATNKPPYDLPAHKTRTVLRTETHQGDGYNELRFEDQAGKEEIYVHAQKDMNLLVENDRKDDIKHDLHLDVANERFTHIKANDHLTVDGEYRSHTKGNKTVVTDASLHLKQGNSLLVDAGREIHFKGGNKIVIEAGAELTLKAGGSFVKIDGSGVSVVGSKINLNSGGTAGSGSGYAGSAPLLPGAVEAATTLEAPTMIVWAQQLEAMKGNVPVCEVCQEHQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2I2</accession>
    <name>D0Z2I2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipase/acylhydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000633</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304926.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000633"/>
    <dbReference type="EnsemblBacteria" id="EEZ39613">
        <property type="protein sequence ID" value="EEZ39613"/>
        <property type="gene ID" value="VDA_000633"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2755">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1247435at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SGNH_hydro" evidence="1">
        <location>
            <begin position="107"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="269" mass="30972" checksum="8F7F307B00F56032" modified="2010-01-19" version="1">MTKEINNRIQNYDASIYKYCLEHKEKSVFDLMASFFSDKSNLDNKILFNQAEQVAKEFNLNLDSDVLLSFCNRLNILQASNAMSQYIGKMDSHKNMSKQHTANIIMFGDSITDWGPWYELFPEKSIVNRGIAGDNTQGMLFRIQDILPLQPKQVFFLAGINDLAQGFTVHEVFSRYCSMLDFCQEHGIEPIVQSTLYVGSRLAQLNPLVEQLNQQLKSYCVDKNITYINLNCVLCPEKTLLPKYTRDELHLTALAYQEWATIIKPLLNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2I7</accession>
    <name>D0Z2I7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Choloylglycine hydrolase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_000638</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C59 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304934.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000638"/>
    <dbReference type="MEROPS" id="C59.001"/>
    <dbReference type="EnsemblBacteria" id="EEZ39618">
        <property type="protein sequence ID" value="EEZ39618"/>
        <property type="gene ID" value="VDA_000638"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3049">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="636485at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029132">
        <property type="entry name" value="CBAH/NAAA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02275">
        <property type="entry name" value="CBAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019930" evidence="3">
        <location>
            <begin position="23"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="CBAH" evidence="4">
        <location>
            <begin position="23"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="362" mass="39438" checksum="5EAB3BCFC7AFF5CA" modified="2010-01-19" version="1">MSKKTILAVALGLTLAPVLTQACTGILVKSEDGKAVAARTMEFGFDVKSNIAIVPAGTEITSLVNDPKNTGLVYTAKYGFGGANALDKKMVVDGVNEKGLYFGAFYFSGLAKFAELTDENKSKAVSSEELGNYILGNFATVDEVIEELKNIVVVGSYIDEIKTFAPFHYAVTDPSGRSIVIEYTEAGLQIHENKIGVVTNNPTYDWHIANLRNYIGLTPYNKEAVEINGVKITPTGEGSGLLGLPGDYTSPSRFVRAATFVNASLPSKTVDDAVFTAFHLLNAFDIPKGAIRSPKHEALTDYTVWTSVVDTANKDYYFKSYLTPMEMKVNIPQALKQIKEPTVVKMENSYTYKDITPQFGTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2M0</accession>
    <name>D0Z2M0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000671</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305016.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39651">
        <property type="protein sequence ID" value="EEZ39651"/>
        <property type="gene ID" value="VDA_000671"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502ZARP">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1432368at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025935">
        <property type="entry name" value="AbiH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14253">
        <property type="entry name" value="AbiH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="319" mass="36866" checksum="59DAE68D5F014A66" modified="2010-01-19" version="1">MKLYIIGNGFDVHHGLDTRYTSFGLYLKNNYWETYELLIDHYGFRDLNPNDPTSISDPLWSEFETSMSLLDKDSVLAANMDAMPNYASDDFRDRGRYTLQIEMKRILGLLTTELYKAFKEFILAVQFPQFDSSRAINIDRDAVYLTFNYTDTLAQYYEVPVENVLFIHEKADEDVEELILGHGVDPENFKEKPAEPPAGLSEEDLEHWMEYQSDQYDYSYERGKDVINQYFSATFKGTEQIIKNNEDFFAGLGNVDEVFILGHSLAEVDLPYFKKLAGSVKTDAKWVATYYDPDDQQTHYETLTGLGITNVSVVRMETI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2P4</accession>
    <name>D0Z2P4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000695</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305080.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000695"/>
    <dbReference type="EnsemblBacteria" id="EEZ39675">
        <property type="protein sequence ID" value="EEZ39675"/>
        <property type="gene ID" value="VDA_000695"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0803">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1703187at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030001">
        <property type="term" value="P:metal ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006127">
        <property type="entry name" value="ZnuA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01297">
        <property type="entry name" value="ZnuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00073">
        <property type="entry name" value="ACYL_COA_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018851" evidence="1">
        <location>
            <begin position="31"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="302" mass="33840" checksum="09B8D37A23B3152D" modified="2010-01-19" version="1">MKKFTLSLTRTVAMTTVVCSALIASVQTHAADILIATPVTYLLASELTQSTPLTTDYLPPKRYGVTRLPNWFASKGDVLSQQAAKKAQVAVTIQAIWPQDPLYVYARQGNIRLIEVDASQAISPRAQGVAALMLDSGEISPYAWLNPTNISRMAAIVSEDLQKVWPEHAKIIEKNQQDLMIEVRKLINQQQNTLMEAGIDSVILLSSELEDFASGNQLFVVDRLTKPELEWNNEDIQQLQALLMDDPNTWLLTSKRLSKKIKDLLPKETKILTIDSIDRWGGKGIDKENPLERWYVELPISS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2W0</accession>
    <name>D0Z2W0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000761</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39741">
        <property type="protein sequence ID" value="EEZ39741"/>
        <property type="gene ID" value="VDA_000761"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="40" mass="4662" checksum="8118EEA0826EE79C" modified="2010-01-19" version="1">MISAGFNVVENINPYWESVGKTFEDIDGYRLVLQNLDWDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2X4</accession>
    <name>D0Z2X4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Maltose/maltodextrin transport ATP-binding protein MalK</fullName>
            <ecNumber evidence="7">3.6.3.19</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_000775</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.6.3.19" evidence="7"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305317.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000775"/>
    <dbReference type="EnsemblBacteria" id="EEZ39755">
        <property type="protein sequence ID" value="EEZ39755"/>
        <property type="gene ID" value="VDA_000775"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1200451at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015423">
        <property type="term" value="F:ABC-type maltose transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03301">
        <property type="entry name" value="ABC_MalK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015855">
        <property type="entry name" value="ABC_transpr_MalK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013611">
        <property type="entry name" value="Transp-assoc_OB_typ2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08402">
        <property type="entry name" value="TOBE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="4"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="368" mass="40902" checksum="7C7A59F1D66A5028" modified="2010-01-19" version="1">MTSVTLRNVCKAYGDNLISKNVDLDIQDGEFVVFVGPSGCGKSTLLRCIAGLEDITSGDLYIGDKRMNDVPPSQRGVGMVFQSYALYPHLNLFDNMSFGLKLAKADKSEIKRRVDHAADILQLGHLLERKPKALSGGQRQRVAIGRTLVAQPQVFLLDEPLSNLDAALRVQMRIELAKLHKQLGCTMIYVTHDQIEAMTLANKIVVLDGGFVSQVGRPLELYHYPQNRFVAGFIGSPKMNFMSVFVEEVENDRVMVQLANGNAFWIPVDGSTVERGSRMSLGVRPEHLVPCCDGDACIEGKVLVVEKLGHETQVYLNMDNVDADFIYRQPDTLDINAGDRLEVGIPAHRCHLFHSDGTACRRLYEEKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z317</accession>
    <name>D0Z317_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative multidrug transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_000818</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305429.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000818"/>
    <dbReference type="EnsemblBacteria" id="EEZ39798">
        <property type="protein sequence ID" value="EEZ39798"/>
        <property type="gene ID" value="VDA_000818"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1558246at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="96"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="129"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="157"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="195"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="217"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="254"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="291"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="319"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="343"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="384"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="422"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="6"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="460" mass="49472" checksum="83CB7A55E140C872" modified="2010-01-19" version="1">MSPQTIFASVALVIALGSLEKSIVTTPLPLIGQDLNAGQALTWVVTAYLLAATAVLPVYGKLSDIFGRVKMLNVSIVLFMLGSVACGLSDSLTQLILGRILQGLGGGGLIALAFTVIADSIPARVVGKYQGYISIVYAVSSIAGPLLGGYFAEHLNWRWVFWINLPLGILAIWMINRNLKHLSTGRKSPFDWKGAGLLMCSTTLTLLILSPEANLPLGWAAFALLLSLVVLYWVERSASDPILPARLARLPGYLVSVSLILCSQLLMFAVLVYLPLQMQWQKGMTASESGLFMMVFMFSITTGAFIGGKLIARWGNYKIFVVLGFLMASLALWQLHFGLWIRVALAFAGLGLGFTLPALSVVVQNVLPSKDRGIGMSLFNFGRELGGAIGVAVCSAVFHFQLPKDIVINKADGLASLEPQLLAQSFNTTYVVMGIFALGAFLSAIILLKSQSLAIDIEKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z325</accession>
    <name>D0Z325_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MFS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_000826</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305456.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000826"/>
    <dbReference type="EnsemblBacteria" id="EEZ39806">
        <property type="protein sequence ID" value="EEZ39806"/>
        <property type="gene ID" value="VDA_000826"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0738">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1121832at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="103"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="130"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="161"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="202"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="244"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="269"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="299"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="327"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="357"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="7"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="390" mass="42047" checksum="F0D60A0651A551B2" modified="2010-01-19" version="1">MKNKITLTAISFLANFIMAGFATQFGMLVEPLATTFNANINEVASIFSLLNGGALAGTIAAFFVIEKIGIKRMTVLCYGAIAVSALSLYIAPSLFIVMLGMTIIGFCGGVGLCIAGTIVVSVWKDKTQSTMLVVQDATFNIAGVVFPLITTYALTHAMNRSISYLSVGVVALATMFVALLTNFKQCHEDAESEHVTQSEWNFGIISGGIGLFLGMLALYTFLTWAPMFVKEKFDIPFEQAGNIITQYWSAALVGALVSTVIVSRMKIQTFLLVIIFIAMLITSIIVTTDKLSWLSYLTYGYGFACAALYNAFIAYGVSFVRNATSKNVSYILISGSAGAMFSPAISSVLESAVGLQTVMYAIPVIYAVIVFMLVVTKKLKPMIKHNKQTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z333</accession>
    <name>D0Z333_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator Dnr</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000834</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000834"/>
    <dbReference type="EnsemblBacteria" id="EEZ39814">
        <property type="protein sequence ID" value="EEZ39814"/>
        <property type="gene ID" value="VDA_000834"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0664">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012318">
        <property type="entry name" value="HTH_CRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13545">
        <property type="entry name" value="HTH_Crp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00419">
        <property type="entry name" value="HTH_CRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51063">
        <property type="entry name" value="HTH_CRP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="2">
        <location>
            <begin position="6"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="HTH crp-type" evidence="3">
        <location>
            <begin position="141"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="225" mass="25601" checksum="8BEBFE282B18FCFD" modified="2010-01-19" version="1">MMSFSIISLLNKTQLEKLASHQEKLICHTGSILFHQGDEANRMYVIEKGKVILYRLMPNGEEKVFNVFLAGDVIAEMALFMSPRQYPMTARIEQDSVLLAYQHNDVKQLVSETPELAVRVMEYMTNKIHSLVNDVNILTQVNANQRFVMKLAEIYKKQGLKTDKINLLTTKKLLATQLGMTPETLSRAIKRLKNEGQIVESGNSLKIVDISELCRSVELTPDIFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z371</accession>
    <name>D0Z371_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">OmpR/PhoB-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000872</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305589.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000872"/>
    <dbReference type="EnsemblBacteria" id="EEZ39852">
        <property type="protein sequence ID" value="EEZ39852"/>
        <property type="gene ID" value="VDA_000872"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3710">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1153219at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="4"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="1">
        <location>
            <begin position="4"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="428" mass="49223" checksum="1207CBB02FD1F989" modified="2010-01-19" version="1">MPTVEQIKFKTDVCYIPSQGMLKADDSTQKLNLSEQYILTFLIDNHQRPVTKEELLKVGWPDRIVTEASLFQIIRALRVKLQEQQKGDIIETLPRVGYQIRDFQRETVSLSQQEQEQSVAEKTWIKPALAVSTVAIMLGSVSWFYLNKDPNIPTFEVKQETIGTNKITYIALNAADLADLEQKADSIYQDNVEIFDKSTIKNRIIYMYKNMSGAYSVAWCRTEDNSNRCIPKTDFSYRISPEKWPAFAKLSSEQGKIFRDTPIIQTELSREPTAQVFTNYMDGSGIKSKVTHYYISKEEDGEMNYSFMSFITEKNSDYHHALSIRAAAVTIDPSRSQFIATTRIEPEMYHWAYADDGLNINKNKSIALNNEINLKNKHNALSVNHTYLLYHQDYLDLMLSASRGLYWVNNSQKVTELFRSSVAQATKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z397</accession>
    <name>D0Z397_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ATP-dependent DNA helicase RecQ family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_000898</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305666.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000898"/>
    <dbReference type="EnsemblBacteria" id="EEZ39878">
        <property type="protein sequence ID" value="EEZ39878"/>
        <property type="gene ID" value="VDA_000898"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0514">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="54580at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004589">
        <property type="entry name" value="DNA_helicase_ATP-dep_RecQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032284">
        <property type="entry name" value="RecQ_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16124">
        <property type="entry name" value="RecQ_Zn_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00614">
        <property type="entry name" value="recQ_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="5">
        <location>
            <begin position="23"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="6">
        <location>
            <begin position="214"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="639" mass="73050" checksum="A5218BA33D56A5CF" modified="2010-01-19" version="1">MYLQTLEKVFGFAQLRQGQDDVISRVLDGHSSAAIFPTGSGKSLCYQLPALLLPHLTLVISPLLALMKDQVDFLQSKGIAAASIDSSQTWDESQNIMQQVRQGDIKILMISVERLKNERFRQFISHVPISLLVIDEAHCISEWGHNFRPDYLKLPEYQKALNIPQVLLLTATATPAVIDDMQLKFGIEKENIVVTGFYRPNLDLNILTSEEDEKFSSLLNQIANDQNQGPTIIYVTLQNTAEWLAEELERHHIHAHAYHAGMSSERRNDIQQQFMQGKIDCIVATIAFGMGIDKSNIRQVIHFDLPKSIENYSQEIGRAGRDGQQSTCTVIANKSGLNVLENFIYGDTPEQSAIIKVLSEIAQAEQHWEVMINRLSRDSNIRLLPLKTLLVYLEIRNIIEPVYSYYAEYRFKFNIPVNDILQHFEGERLQFLQAIFSCSPKAKVWHTLDFTALWQLYQCERQRVVAAMDYLAQKGWLTLESKQMTDVYKITHSSFNIEDEAKALYDLFHNKENNEINRIDEMIGFFESKECLSYKLAQYFGDENAPKQCHHCSVCRGKTATLPAIVLAEPIDNRKITQWCDEFIAKCNEQPEASVLSRFLTGMASPIHTTIKAKSLKGFAQLEHYPYKDVLEHVKQCYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3G3</accession>
    <name>D0Z3G3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Signal transduction protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000964</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305850.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000964"/>
    <dbReference type="EnsemblBacteria" id="EEZ39944">
        <property type="protein sequence ID" value="EEZ39944"/>
        <property type="gene ID" value="VDA_000964"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2905">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="301791at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008773">
        <property type="term" value="F:[protein-PII] uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018821">
        <property type="entry name" value="DUF294_put_nucleoTrafse_sb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005105">
        <property type="entry name" value="GlnD_Uridyltrans_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03445">
        <property type="entry name" value="DUF294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10335">
        <property type="entry name" value="DUF294_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0129">CBS domain</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="2">
        <location>
            <begin position="17"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="3">
        <location>
            <begin position="156"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="3">
        <location>
            <begin position="228"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="625" mass="70837" checksum="97CB2FF8CBFAF893" modified="2010-01-19" version="1">MEVEQIEVLNFISQYPPFDDLPEDRLKEIALNVEISYYRAGTTIVNFGDAIHDLFMVRSGTVEIYRRKGELYNRIDTGGLFGQMGLLMNNKVRLPAKATEDTLVYCIPEAIFNELCDEFDNFADFMELEDSARLRSVVSNHAEGNDLTTVKARKILTREPVIIDASESIQAAANLMAEENITALLVANSESSDSEEHDHLLGILTDRDLCIRVLAQGIDTNLPISEVMTTDVISLDYNAYVFEAMLMMLRYNVHHLPIIKDKKPIGIIGLTDIVRYESQNSLLLVSSIYQQQSVEELKSISTQVKDCFVRMVGEDANAHMIGNAMSVIGSSFKQRLAELAEAELGPAPIPYCLVAMGSMARDEQLIVTDQDNALILDDSYDEAIHGNYFAQFAKFVSDGLAECGYSYCDGDIMATNPQWRKTRTEWEECFAEWIDHPNPERLLHSSIFFDIAGVYGRVKWAEQLNSFIVRRAKKNNRFLACLAHNAINRTPPLGFFKDFVMEKDGRHRNSINLKRRGTAPLADLIRVHALAVGSQQQNSFDRLDDIIDAGILPKGRGQDLRDAMELIYMVRIRHQALDIENGDEPDNSIEPENMSEFERRNLKAAFQILSNAQNFIKFRYQRNSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3H6</accession>
    <name>D0Z3H6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AraC-type DNA-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000977</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305889.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39957">
        <property type="protein sequence ID" value="EEZ39957"/>
        <property type="gene ID" value="VDA_000977"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1785082at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009594">
        <property type="entry name" value="Tscrpt_reg_HTH_AraC_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06719">
        <property type="entry name" value="AraC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="2">
        <location>
            <begin position="196"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="294" mass="33242" checksum="B0AB8BBF609A3D1E" modified="2010-01-19" version="1">MQLKRSMELYVEKQQLNHLEGIYQTAIPEVYFYRSSKGNQRQPFTYQSGLIILGQGHKNIHIGDEAVHYGEGDYLVVGMPMPLECEAFPDNEQSLLGISVNIPPQLLHRLVQQLEAKGFRPQKENPVTCGCLQSVAMDSAMHDCCIRLMNALCNEVETDILGNALVEELAYRALIGREGHLLFELAHSEGHYARIAKALNKVHLSFDEPLTVQQLAEEASMSVSAFHTAFRNVTLESPLQYIKKVRLNKAKELIHIEGKRVNEAARMVGYTSPSQFSREYKRHFNETPKGTVFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3J6</accession>
    <name>D0Z3J6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GGDEF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000997</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305944.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000997"/>
    <dbReference type="EnsemblBacteria" id="EEZ39977">
        <property type="protein sequence ID" value="EEZ39977"/>
        <property type="gene ID" value="VDA_000997"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3706">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041617">
        <property type="entry name" value="TPR_MalT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17874">
        <property type="entry name" value="TPR_MalT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GGDEF" evidence="2">
        <location>
            <begin position="573"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="518"/>
            <end position="545"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="719" mass="83712" checksum="28B567A52692BF3A" modified="2010-01-19" version="1">MAEHPILSEILTILTRLPQCTGLEEVQQTHQQVLAMAHQHKINFPDEFEQFITAYEAYRSNNMAKAIPTFLHCQRICYQQHSAVLSLYCDIHLGTIYTMLGQFQHGLTHFLKAYKNSNLKDRNFQMLLNLNIGDAYLLLNDFKQGERYCRKADKLALELDDLNCISLAKMNVALALAHQGDLIDSEAWIQEAIHYAQKTLCQRTLGYAWSYQGRISAIQNNYSKAKHSYITSDYFFAQSYEYFGRSENQYFYALLLLKKNKLKAALNHCQQAEKLISNEEHYQAKNRLYHLQVQIYQQQGDFDKANNILALQAKEANDEITRSAGRGTRYMDYILPLGEQKRQFDNLQQLHNNLSVITKIGQQIATANNLRAHLPEIYQQLNLIIPIHVFGIALYDQAQHQLNYDYFIEDGAVIPPIIIRCEDDSSLGAYSVAHQQQLHLNTSSKQDLAVYVDPQKMDRQLFQGNDEKTQSIIITPITLNEITIGVLFLEHHTPYLYQQHHCDLAKQLAGYIAVSLENLRQTNILKQQQQELEAVNQRLNTLSRYDALTQLFNRYELDTIAPNLINEAQKQQKSLTCLMIDIDFYKTFNDHYGHQQGDKVLRLVAKFIHQAFSEQQDFAFRYGGDEFLLLAFNQSQEQIQTKVEQLQQYLEQENIEHHYSQCSERLTLSIGSYTWQPDSFDDLTVESLIHQTDQALYFAKQKHRNRYVTYQQRQQEQID</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3Q0</accession>
    <name>D0Z3Q0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001051</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001051"/>
    <dbReference type="EnsemblBacteria" id="EEZ40031">
        <property type="protein sequence ID" value="EEZ40031"/>
        <property type="gene ID" value="VDA_001051"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2990">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007488">
        <property type="entry name" value="DUF535"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38785">
        <property type="entry name" value="PTHR38785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04393">
        <property type="entry name" value="DUF535"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="271" mass="32212" checksum="3AC79EB44031E7B2" modified="2010-01-19" version="1">MVRALIHAAQFKRMSAYFHQGNRLKLFEKQPNFVTKCITPYLRDGFTKDQRVDILINHYQWFEQVFTAQAQCAIYQDNVVLCELSIDEERYFVTLSFERNSRKEGELTLSLCDEQHNKYYVIAFTYIAGDFYIGCMQGGANDNGFSRKFTKAFYGLRPKSFMVETMQLLAQLLHIPHLYAVKNSGHIYNAKRYGKKAQTINLNYDQLWEEHDGEVYDEWFYQLPLESKRRAMEDIKRPKRKMYRERYEWLDGYKDQLAQSLEPLLNSSTVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3Q6</accession>
    <name>D0Z3Q6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative ThiJ/PfpI-family thiamine biogenesisprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001057</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306104.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001057"/>
    <dbReference type="EnsemblBacteria" id="EEZ40037">
        <property type="protein sequence ID" value="EEZ40037"/>
        <property type="gene ID" value="VDA_001057"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0693">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1421548at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DJ-1_PfpI" evidence="1">
        <location>
            <begin position="5"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="192" mass="21566" checksum="E8892DD1F53653ED" modified="2010-01-19" version="1">MSETKRVAVLLADGFEEGEAVVFIDIMRRLDIEVDVLSCMETTALNTYFKTKITADYTLIEKFDETYDAVMMPGGPQGTDNLTANTSVIAFLKRHIDANKYICALCSSGAKVLAAHHLFQGRPYTTGDKLADKFDDGDFRIQKVVVADNFITGRGLGVSFEFAFTVAKYLLSDNQEKVDWQANHIYFEHWPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4A9</accession>
    <name>D0Z4A9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Nitrite transporter NirC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_000365</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FNT transporter (TC 2.A.44) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304163.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000365"/>
    <dbReference type="EnsemblBacteria" id="EEZ39347">
        <property type="protein sequence ID" value="EEZ39347"/>
        <property type="gene ID" value="VDA_000365"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2116">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1834167at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000292">
        <property type="entry name" value="For/NO2_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024002">
        <property type="entry name" value="For/NO2_transpt_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30520">
        <property type="entry name" value="PTHR30520"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01226">
        <property type="entry name" value="Form_Nir_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00790">
        <property type="entry name" value="fnt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01005">
        <property type="entry name" value="FORMATE_NITRITE_TP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01006">
        <property type="entry name" value="FORMATE_NITRITE_TP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="25"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="60"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="148"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="182"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="228"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="272" mass="29198" checksum="4DF92F2C0A5C8308" modified="2010-01-19" version="1">MFAEPIKKCGDNAARIKRLASENPFGFWLSSAMAGAYVGLGIILIFTFGNLVDPAIRPIVMGATFGVALTLVIIAGSELFTGHTMFLALGAKTKQISWRDNAIILPQTWLGNLLGSIFVAALFMYAGGGKLLPDATSLVHKVALAKTMAPASVLFFKGILCNWLVCLAIWMCQRTDGASKFIAIWWCLLAFIGSGYEHSIANMTIFALSWFGQSAADFTLAGIGHNLLWVSLGNMVSGAIFMGLGYWYVTPKNERPVTVSDAQACTSNPAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4B9</accession>
    <name>D0Z4B9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000375</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304192.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000375"/>
    <dbReference type="EnsemblBacteria" id="EEZ39357">
        <property type="protein sequence ID" value="EEZ39357"/>
        <property type="gene ID" value="VDA_000375"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0697">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1515911at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="162"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="226"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="261"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="285"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="6"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="162"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="326" mass="35266" checksum="7363C1C2257E7D33" modified="2010-01-19" version="1">MNRTAMGWTAAIFIGLLWGIPWIVGTPILKVMDAQVLVWARYTIAFLTLAIILNVGIATGKLEKKKDFKLNWENRHDIIWSAACGIIGQGAFSFLSFLSLDYITASENGVIQGLIPILILTVGFFRHNARFTTLQMVAAVGAFVGVAILVMDPKSETNGFNIGHLICFGSAASFATMAYARAELAEKYGSVATMFHQFIFASIGFGLYLVFTGADLSSALGIFSSPLRILCITILGVGISGISYLIYIYAMERVGVDGTGMALNLMPLSSFVLAVFALGESVTPMRLLAIAVVIVSMMMFMKFGNDKAKETEKQKSSATELTTQKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4D1</accession>
    <name>D0Z4D1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Putative pseudouridine methyltransferase</fullName>
            <ecNumber evidence="5">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_000387</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the methyltransferase superfamily. TrmY family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304224.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000387"/>
    <dbReference type="EnsemblBacteria" id="EEZ39369">
        <property type="protein sequence ID" value="EEZ39369"/>
        <property type="gene ID" value="VDA_000387"/>
    </dbReference>
    <dbReference type="GeneID" id="57343232"/>
    <dbReference type="eggNOG" id="COG1901">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1311630at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008175">
        <property type="term" value="F:tRNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18087">
        <property type="entry name" value="TrmY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00587">
        <property type="entry name" value="tRNA_methyltr_TrmY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007158">
        <property type="entry name" value="TrmY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40703">
        <property type="entry name" value="PTHR40703"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04013">
        <property type="entry name" value="Methyltrn_RNA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ39369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="199" mass="22263" checksum="EB7E4C506E2E512F" modified="2010-01-19" version="1">MRAFVVRARAASTDKDTFVAAVGQEDHSEILAHVLMNAIFTAQSHRDDVVVYLVLESTRDFSRTIRFESSKIHNIGGFHEAALINKIAGALGASVGMAKEQVREVESGITVETVSFERLVQRLAEDYQLFLLDKKGTNFREQELEGDLCFLLTDHIPMPKKTINSLKRLNTLPISLGPKMLFASQCIVLIQNELDIRGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-06-02" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4E3</accession>
    <name>D0Z4E3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000399</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39381">
        <property type="protein sequence ID" value="EEZ39381"/>
        <property type="gene ID" value="VDA_000399"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031TA1">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="126" mass="14850" checksum="BB20D0256EA3C985" modified="2010-01-19" version="1">MVSEEEMQELFTFEQEETENEERLKSAQFDAMLRMTAIALSEVNEAFAHTDNAKQNIERMTRLLLWHFYAMSFQLEEAVTLEQHCEEVEKILQNPAKNAFEWVQTLTELLHRYASLSGFSEPEENK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4N1</accession>
    <name>D0Z4N1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Chitinase</fullName>
            <ecNumber evidence="5">3.2.1.14</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_000489</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.2.1.14" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304507.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000489"/>
    <dbReference type="EnsemblBacteria" id="EEZ39469">
        <property type="protein sequence ID" value="EEZ39469"/>
        <property type="gene ID" value="VDA_000489"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3979">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1584918at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004568">
        <property type="term" value="F:chitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016998">
        <property type="term" value="P:cell wall macromolecule catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006032">
        <property type="term" value="P:chitin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003610">
        <property type="entry name" value="CBM_fam5/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036573">
        <property type="entry name" value="CBM_sf_5/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000726">
        <property type="entry name" value="Glyco_hydro_19_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02839">
        <property type="entry name" value="CBM_5_12"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00182">
        <property type="entry name" value="Glyco_hydro_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00495">
        <property type="entry name" value="ChtBD3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51055">
        <property type="entry name" value="SSF51055"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018853" evidence="3">
        <location>
            <begin position="25"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-3" evidence="4">
        <location>
            <begin position="446"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-3" evidence="4">
        <location>
            <begin position="520"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="483"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="501"/>
            <end position="516"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="562" mass="61980" checksum="997F9F276C1FB1F2" modified="2010-01-19" version="1">MSKLRPIACVISSALILGSLSTQALTIEPDPENPGGYIIPKADIQAAEESKTADPMYAVWAKALQTTSNKVVEAILPGLDSNPDNVKRAERVFPEYEWDFLTGMAAPEYTYTRFLRAIGKFPAFCGEYTDGRDSDAICKKSIVTAFAHFAQETGGHIGKDNAWDNPLGLEEWQQALVHVREMGWSEGQEGYTTGCGQNDWQNKRWPCEKGQGYFGRGAKQLSYHFNYGAFSEVMFDGDATVLLKNPALVADSWLNLASAIWFFLTPQAPKPAMLHVIDRTWVPSERELDAGIGYGFGTTINVINGGIECGEQNKDKGQPVNRIRYWEGLSSHYQIPIESDEKNTCWQQTPYGSINLNGAKDVLYTNWEASWKYHSDRPGGVSFECELVGYQTAYSALTPGDYEKCVTNFYGSHANWPAVRIVDKIDGGDGNGGGTTDPTDPPVSTVPAWEASKVYVGGNEVSHNGKLYQAKWWTQGDRPDAGGPWKYIKDISGDDTGPTDPEPPVVVPPTDPSEPPTTMLPTWDSSNVYVGGDKVSYNGKSYQAKWWSQGNQPDKGDPWKVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4U2</accession>
    <name>D0Z4U2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">TnpA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_000175</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the transposase 7 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000175"/>
    <dbReference type="EnsemblBacteria" id="EEZ39159">
        <property type="protein sequence ID" value="EEZ39159"/>
        <property type="gene ID" value="VDA_000175"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4644">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002513">
        <property type="entry name" value="Tn3_Tnp_DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01526">
        <property type="entry name" value="DDE_Tnp_Tn3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0814">Transposable element</keyword>
    <keyword evidence="3" id="KW-0815">Transposition</keyword>
    <feature type="domain" description="DDE_Tnp_Tn3" evidence="7">
        <location>
            <begin position="375"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="89"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ39159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="782" mass="90501" checksum="F7D50A434A2C68CD" modified="2010-01-19" version="1">MKKSPGSATLRNFRKWENRLVLLDAILDTKPFLKKVAYTKIRQFASEALAYEINDMRGIHNEAKRYTLLLCLLFQTQINTRDELIEMFLRRMKRVHNTAQENLKNLQDKHREMEEELIAVFGQVLQHAKIVETNEVLGEKVRELLEARGGVEAIDTRFNMVTAYHHNNYFPLLWPVHKSNRAVIFRVLDSIEICSSTQDVTLLRALDFIRKHRNTRKDLLPPEIGLQFTTQRWVSLIQKKTHFGILYDRRSLEVCVFIHLAEALQSGDLYVENSGVYSDHRKQLEPWSECLKRLPDYCQELGLPDTASEFVKSLRQQLTTVANKIDKGFPKNSELTIDSDGTPHLKRQKVSVLPKGLDEFKDQVYGRMPERNLLDILRNVQHWSNYSRCFSPPAGTDAKLSDPHSSYLYTVFGFGCNLGASQTARHAPKNIHRQTLRRVNTQHINATKLEAASNKVISEYARFELPEFWGKSNVVIADGTQTELRKNNLLGEQHIRYDGFGGIAYHHISGEYIALFSHFISCGVWEAVYILDALILNQSVYQPDTLHADTQGQSEPVFGLAYLLGIKLYPRMRTWNDVAFYRPDGNAKYEHIDKIFKKTINWELIETHWQDLMQVVLSIQAGKVLSSMLLRRLNGHNRRNKLYRAFRELGRVMRTLFLLRYISEEDLRHTIRAETTKVESYNNFQDWISFGGEIIKSGDPVEQAKQIKYANLIANSIMLHNVSDLTGILNEMASEGIVITKELVSCLSPYIREHIRRFGRYDVDMTERPPDLDPRPVPIDEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4W0</accession>
    <name>D0Z4W0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Type III secretion inner membrane channel protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">VDA_000193</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306568.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000193"/>
    <dbReference type="EnsemblBacteria" id="EEZ39177">
        <property type="protein sequence ID" value="EEZ39177"/>
        <property type="gene ID" value="VDA_000193"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4789">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.540">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042194">
        <property type="entry name" value="FHIPEP_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042193">
        <property type="entry name" value="FHIPEP_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042196">
        <property type="entry name" value="FHIPEP_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025505">
        <property type="entry name" value="FHIPEP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001712">
        <property type="entry name" value="T3SS_FHIPEP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006302">
        <property type="entry name" value="T3SS_HrcV"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30161">
        <property type="entry name" value="PTHR30161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00771">
        <property type="entry name" value="FHIPEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005419">
        <property type="entry name" value="FlhA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00949">
        <property type="entry name" value="TYPE3IMAPROT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01399">
        <property type="entry name" value="hrcV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00994">
        <property type="entry name" value="FHIPEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="74"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="106"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="202"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="233"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="281"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="305"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="333"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ39177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="707" mass="77937" checksum="AAEFB9E508B216EB" modified="2010-01-19" version="1">MNKLKLIDILNKAGQRKDIMLAVMLLAIVFMMILPLPTALVDVLIGTNMSIAVVLLMLAIYITTPLEFSAFPAVLLITTLFRLSLSITTTRLILLQGDAGQIVYTFGNFVVGGNLVVGIVVFLIITIVQFMVITKGSERVAEVGARFSLDAMPGKQMSIDGDMRAGVIDVHEARHRRSLIEKESQMYGSMDGAMKFVKGDSIAGLIIIVVNILGGVTIGVTQKGMSASEALELFSILTVGDGLVSQIPALFIAITAGIIVTRVSNEDSSDLGSDIGGQVTAQPRALLVGGVLLILFALIPGFPKVTFLILAAIVGGGGFFLFYQQKKQSESDSSDLPSFVAQGAGSPAAKPNRPTSSRNSKGKLGEQEEFAMTVPLLIDLDSRLQESLEAVALNDELARVRRALYLDLGVPFPGIHLRFNEGMSNGEYLIQLQEVPVARGRIESEKMLVTEGNEQIDLLGVPYENDDDFLPGIVSIWVDHSHREKLQNSHVGFLTPDCILTYHLSHVLKEYAQDFIGIQETRYLLEQMEGSYSELVKEAQRIVPLQKMTEILQRLVSEDISIRNLRVILEAMVEWGQKEKDVVQLTEYIRSSLKRYICYKYASGQNMLPAYLLDQSLEDTIRNGIRQTSAGSYLALDPSVTQQFVSDVKQTIGDLSRMPNKPVLVVSMDVRRYVRKLIESEYYELPVLSFQELTQQINIQPLGRVGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z519</accession>
    <name>D0Z519_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Response regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000252</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306740.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39236">
        <property type="protein sequence ID" value="EEZ39236"/>
        <property type="gene ID" value="VDA_000252"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1766230at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010297">
        <property type="entry name" value="DUF900_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05990">
        <property type="entry name" value="DUF900"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="366"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="2"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="391" mass="45102" checksum="0F5F21EA02848820" modified="2010-01-19" version="1">MKVLVVDDNLPRCKEILDLLKSSAGVNEQDIYTCHNTQSAKKILRNIRFDFMILDVVLPKRSETPSANFGLALLSDIKKRPNILKPNKIVGITAHTDDIASFKDEFENHCEIVIEASHRNKTWKSRIIDSIKFETVKSVSKYTSTNNVTCLSVHGIRTFGKWQQDLKKTIESHVSSVNFEHYKYGYFTVISFFIPFLRNLQVKKFKQALLEIIKRKNDDEIIIFCHSFGTYVVVNAIDSLIKNGANCNKISKLVLAGSVLKSNYDFTNILTQTNMKIINDCGYNDNILLLSEGFVPNTGMAGRVGFYGLNNQRFSNRYFSGGHSHYFDKSNNFIEKYWLPLFFRDSDLNIVDDRNFITFRSRLIEMVFHTIGTVKELFYIIFAIWLLFNLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-02-10" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z521</accession>
    <name>D0Z521_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Riorf46 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000254</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39238">
        <property type="protein sequence ID" value="EEZ39238"/>
        <property type="gene ID" value="VDA_000254"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2801">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="2">
        <location>
            <begin position="124"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="404"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="450" mass="52953" checksum="B6866CBB5CC88DD2" modified="2010-01-19" version="1">MNDKEIFRLGTIRDVCEKRIRRKDAAQLLNVSVRQVQRLITRYRDLGAASLVHQRRGQSPGNKINADIRHQCLNLIHEYYADFGPTLAREKLIERHGIKIGLETLRQWMIADGLWVPHFKRKPRVYQPRYRRDCYGELIQIDGSHHDWFEGRSNKCCLLVFIDDATGKLMNLRFSETESAFDYMVATREYLEQHGKPTAFYSDRHAVFHVSKRDAKTERLTQFGRVLHDLNIELICANSSQAKGRVERANKTLQDRLVKEMRLQEIDTIEQANVWLPDFIADFNRRFAKPAKYPKDMHRPVREMTDELNDIFAWQELRKLSKSLTFQYDKVVYLIDPTEENQRLINQVVKVLDRPDGTIAIQYGLRKLTFKVFDKLTDIDQGQIVDNKRLGAVLKFAQEKQQEFEQQQTRNRSKKAPKRTAQQRAIRQLEAINPVLVHPEQFKPSTRKKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z523</accession>
    <name>D0Z523_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000256</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306753.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39240">
        <property type="protein sequence ID" value="EEZ39240"/>
        <property type="gene ID" value="VDA_000256"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3316">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1667004at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032874">
        <property type="entry name" value="DDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13610">
        <property type="entry name" value="DDE_Tnp_IS240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_IS240" evidence="1">
        <location>
            <begin position="70"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="228" mass="26771" checksum="A7B9F1B72B73737A" modified="2010-01-19" version="1">MQFSGYHFPSDIILQAVRYYVAYKLSFRDIEEIFAERGIRVDHATVNRWVIRFAPLIEQNARTSKHYVSSSWRMDETYIKIKGKWWYYYRAVDKYGDIVDFYLSQTRDEKSAQAFLRKAIRTNGLPEKVVIDKSGANAQALHNMNIQLWKSVVFMLNLIEVIDVKYLNNIVEQSHRPIKQKMYQALGWKSVEGAQATMSGQEVWTQIKRGQVGELSLPVWERFYALIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z573</accession>
    <name>D0Z573_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000032</name>
        <name evidence="3" type="ORF">VDA_000123</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000005">
        <property type="protein sequence ID" value="EEZ39047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306911.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000005.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39047">
        <property type="protein sequence ID" value="EEZ39047"/>
        <property type="gene ID" value="VDA_000032"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39107">
        <property type="protein sequence ID" value="EEZ39107"/>
        <property type="gene ID" value="VDA_000123"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031P1H">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2062220at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="108" mass="11549" checksum="46B23D673BF89626" modified="2010-01-19" version="1">MNTLAFSAPSIFMAKNKNIIMTALLALFPVAMTFVPDLAYAADMFAEGKQEIIDSTGKDSTLWFSMTAVGLAFALVLGFTTKNWFAAIGGFFIGMIFMNVAAGFIGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5A6</accession>
    <name>D0Z5A6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC-type antimicrobial peptide transport system permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_000156</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005307005.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000156"/>
    <dbReference type="EnsemblBacteria" id="EEZ39140">
        <property type="protein sequence ID" value="EEZ39140"/>
        <property type="gene ID" value="VDA_000156"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0577">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="768211at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="275"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="328"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="369"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="9">
        <location>
            <begin position="19"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="8">
        <location>
            <begin position="305"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ39140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="404" mass="44184" checksum="46D19B85774E3E7C" modified="2010-01-19" version="1">MISLLQQTWLTLIAHRIKSMLAIIAIAWGVISVVVLIALGEGFYRHQTQQLSFMVNNVQIVFPSSTSKPWQGLPLRRQIQIPQDKVDMIKKTGFVKVASSVYVKQDASVTNDKGQSLTNNVSGIDLSYFSLIQRKLKSGSRNLSPSDITNHTRVAVLGEQIAKMGEISIGQMIKVNGIPFLVIGIIKDEDAGISFGDSRKVFIPQTTYLDLWDAKPWMLLLEPIDGIDGPAFRQAIVNFYAKQLHFDPTDREAINLPDFNEGTALITGIFRGIQIFLGASGVMTMAVGALGVANIMFLSVTERTREIGVRLAIGATQKSIRSQFILEGLFLVVVGTALGLMAAYMIVALLGSISLPDWLGIPEITLDSIAWSLLVTLVLALLASYFPARRASRLTPVIALSART</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5B4</accession>
    <name>D0Z5B4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Usher protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">VDA_000021</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Cell outer membrane</location>
            <topology evidence="2 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the fimbrial export usher family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000005">
        <property type="protein sequence ID" value="EEZ39036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005307044.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000005.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000021"/>
    <dbReference type="EnsemblBacteria" id="EEZ39036">
        <property type="protein sequence ID" value="EEZ39036"/>
        <property type="gene ID" value="VDA_000021"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3188">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015473">
        <property type="term" value="F:fimbrial usher porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009297">
        <property type="term" value="P:pilus assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2610">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000015">
        <property type="entry name" value="Fimb_usher"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018030">
        <property type="entry name" value="Fimbrial_membr_usher_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042186">
        <property type="entry name" value="FimD_plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025949">
        <property type="entry name" value="PapC-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043142">
        <property type="entry name" value="PapC-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025885">
        <property type="entry name" value="PapC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037224">
        <property type="entry name" value="PapC_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30451">
        <property type="entry name" value="PTHR30451"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13953">
        <property type="entry name" value="PapC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13954">
        <property type="entry name" value="PapC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00577">
        <property type="entry name" value="Usher"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141729">
        <property type="entry name" value="SSF141729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01151">
        <property type="entry name" value="FIMBRIAL_USHER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="10" id="KW-1029">Fimbrium biogenesis</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0732">Signal</keyword>
    <keyword evidence="6 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="4 10" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003020113" evidence="11">
        <location>
            <begin position="30"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="domain" description="PapC_N" evidence="13">
        <location>
            <begin position="36"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="PapC_C" evidence="12">
        <location>
            <begin position="729"/>
            <end position="787"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF13953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF13954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEZ39036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="803" mass="87572" checksum="AA3579DF510C4E40" modified="2010-01-19" version="1">MNNKHQNKKKSQYSLSLLTLALFSPSLYAQNELDFSFLQGANTQVPEVLKQSSGNVLGQYLVDVFLNGKKIGRQTLTISQNEKQSLCLSPAWLMQLDLPINYKKMSSAFNSTLQCYNFEQIQGGKANFDYSQQSLKLSLPQIVLLHNNQSEHWDYGTPGFRLNYNVNGNKSIGHGLTKNTQGLYGNFDLNANHGQWVFSAKVSGTNTTGFMSSGLTLSTAIQSVRGDLIIGKSFTQSSILPDFSFYGASLRSNSAMKSWSARGYAPVIDGVLNSNSLITVKQGDYVLYSKTLPAGPYSLTDISPISNGDITVTVTGGNGTIISTRKYPVTTLPTLLRMGDFNYNFATGIRENSSQIDGIFGLASLDYGLDFGTINFASIIHPQYQSIGSGVTVPLGEYGAISTSLNTAWSHYDSAAFQPSGERTQRGLSATLQYAKDFGQDTNLQLLTYRYSGEGYNDFSSFYPRGIHVESDKRSRYEAIITQRIGPAYLNASGWAQDYRNGRRRDSGANLTLSGTIGKGIYLGLNGSYTHSGTSGSQYSTSLSVSIPFDLWEQNQYSNSSISYDSISGTSFNTGMSFSTSDRVTNNVNVSLGEHQRTASLYTGVRFDTAQTGFSVSQSEQSTALSANISGSIAGAQGVGLAYSNQQNDTIAIAHIKGLKDIKFNSSSPTNQWGNTIIPLSSYQPNTITVDTNNIPENVELLNSTYRVVPTNQAIIVRDYKYKTVNRYLLRILNKQGQPLPMGTAVQTNKGIDVGFIANGGVLFATLLSPSKYLKLQDNNIKCKIDITNIKPGSSQVTDVHCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5J9</accession>
    <name>D0Z5J9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">IncF plasmid conjugative transfer protein TraG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000017</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000008">
        <property type="protein sequence ID" value="EEZ38991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005307269.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000008.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000017"/>
    <dbReference type="EnsemblBacteria" id="EEZ38991">
        <property type="protein sequence ID" value="EEZ38991"/>
        <property type="gene ID" value="VDA_000017"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4678">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="29010at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012931">
        <property type="entry name" value="TraG_N_Proteobacteria"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07916">
        <property type="entry name" value="TraG_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="326"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="362"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="416"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="domain" description="TraG_N" evidence="3">
        <location>
            <begin position="7"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="579"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="659"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="815"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="675"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="815"/>
            <end position="852"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ38991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="903" mass="98973" checksum="CF95391699705661" modified="2010-01-19" version="1">MANVYDVYVFSGGATAEKVFNAIATFLRGDSYGHLLAIVGMCALLMTMFRFFTSRDHTHLLSYIAVNLTVSSMLLIPTATVRIDDSSMSGRTYFVDNVPIGVAAPIHYATTFMYGLARATDVIFTLPNEAAYTKSGMLFGSKLVGLSQRIGIQDGELKQLWGQYTQNCIRKDITINKKYTWTQFAQAGDIFEFLKNNRPSPVRRIAMNGAFPTCQEALPLLENKFRDEANKSFRLMSTETVINGWATNEALLQNAVVSSYRTFHNINKSASDLLKQNIAVNGVKSGLLDGAASTGATAAAFNYAATHSQMQTQSFMTSMGINAAEWLPIVNSVLILLLACSSIPVFLAAFIPGMTVRVLKGYLGGFFYLALWPFFFTVINLIMTYSLQYAGAESTNLLHGMSLAGSSPLQAMHYKYAAIAGWLMMMVPIISKYALTGGLAMAGSLGQQFLGAMGSNAARSSQAAASGDMTYGVVQTDTWYSNSMSGNKVDTAYSNQSYGAQVQRADGSSVNYLPGGNAVYSSRGAISTTGFDINSSEVQSRALQNSYIEAQRATTQARTAYNQSAGSVADQLMSLSSSASRNTSYGEGTQYSSNSSTQNSLNKLDGVVAEEAKAKGVSKEEAYKHMVDNYFDYNANFGASLGMGVGEFGNIKGGANFTGGQKFTDSESTTDSQRQDRTSRTSNSRQNQFNDLMSSIEQFGTSGRTEDLHGFNQQSISTLSEAIKDSKDLVKTVDSSIAKEQAYSAALQDSQTGSLSINTNLMPEFQAYVARRRPENVEAIMNGNTPAINEERDLFFQAFMSERFSNYNPELKQAWDESSMNRPAQSVQGRDIQGNYERNSGSIESQYQTEQGHRQKQFDEESEQSQQALYNNDAYLHIKQEQENAHQLTEQELKEVKKYRGMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVI2</accession>
    <name>D0YVI2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase</fullName>
            <shortName evidence="3">SEPHCHC synthase</shortName>
            <ecNumber evidence="3">2.2.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Menaquinone biosynthesis protein MenD</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">menD</name>
        <name evidence="7" type="ORF">VDA_001562</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>2-oxoglutarate + H(+) + isochorismate = 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-carboxylate + CO2</text>
            <dbReference type="Rhea" id="RHEA:25593"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29780"/>
            <dbReference type="ChEBI" id="CHEBI:58818"/>
            <dbReference type="EC" id="2.2.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
        <text evidence="3">Binds 1 thiamine pyrophosphate per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Quinol/quinone metabolism; 1,4-dihydroxy-2-naphthoate biosynthesis; 1,4-dihydroxy-2-naphthoate from chorismate: step 2/7.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Quinol/quinone metabolism; menaquinone biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TPP enzyme family. MenD subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.9" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001562"/>
    <dbReference type="EnsemblBacteria" id="EEZ40536">
        <property type="protein sequence ID" value="EEZ40536"/>
        <property type="gene ID" value="VDA_001562"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1165">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00079"/>
    <dbReference type="UniPathway" id="UPA01057">
        <property type="reaction ID" value="UER00164"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070204">
        <property type="term" value="F:2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009234">
        <property type="term" value="P:menaquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01659">
        <property type="entry name" value="MenD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004433">
        <property type="entry name" value="MenaQ_synth_MenD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032264">
        <property type="entry name" value="MenD_middle"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012001">
        <property type="entry name" value="Thiamin_PyroP_enz_TPP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme-bd_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42916">
        <property type="entry name" value="PTHR42916"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16582">
        <property type="entry name" value="TPP_enzyme_M_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02776">
        <property type="entry name" value="TPP_enzyme_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004983">
        <property type="entry name" value="MenD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00173">
        <property type="entry name" value="menD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 3" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0474">Menaquinone biosynthesis</keyword>
    <keyword evidence="1 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TPP_enzyme_N" evidence="5">
        <location>
            <begin position="1"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_M_2" evidence="6">
        <location>
            <begin position="172"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_C" evidence="4">
        <location>
            <begin position="406"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="560" mass="60690" checksum="B25704003558CA2F" modified="2010-01-19" version="1">MLEELTRLGVEHICIAPGSRSTPLTLAASNNPKLTIHTHFDERGLGFMALGIAKASQKPVAVVVTSGTAVANLLPAVAESGLTGEKLVMLTSDRPAELIQCGANQAIRQHGIFSSHATAFIDIPSPTLDISPSWLLAAIDDLMQQQTQRGGTVHFNCHYPEPLYGQDFDFTEYLSPVAYWQNHELAYCQHLSSIHADFVQSQTEWPRFTSKKGVIVVGRVLPDELTSIKALATTLGWPILVDPQAGGSSEWAGFDVWMQNPAALDALSQAQVLLQFGGRIVSKRLLQWIGQQQWQAYWLLDPLAGRLDQWHLSAQRIQTNCGQWAQDAKQMVQSSPQADWALSLQTAASNTAQLVASETTELSELALATHLHHWLPTGTELFLGNSLIVRLLDMVGTLPETATFANRGASGIDGLIATAAGVQKARQTPMVCLIGDTSLLYDLNSLALLTQAQQPMVVIVTNNNGGGIFDLLPVPDQQKDDFYRMPHGLSFAHAAAMFGLNYQCPSSIEELASAVRDGLTPQEAHQATSQTTVIEVVTPSGEAGDMLKALFTKVKNASLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVP5</accession>
    <name>D0YVP5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Hypoxanthine phosphoribosyltransferase</fullName>
            <ecNumber evidence="2 4">2.4.2.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_001210</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Purine salvage pathway enzyme which catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of hypoxanthine to yield IMP (inosine 5'-monophosphate). To a lesser extent, can also act on guanine leading to GMP, but shows a highly less efficient activity with xanthine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>diphosphate + IMP = 5-phospho-alpha-D-ribose 1-diphosphate + hypoxanthine</text>
            <dbReference type="Rhea" id="RHEA:17973"/>
            <dbReference type="ChEBI" id="CHEBI:17368"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="EC" id="2.4.2.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Purine metabolism; IMP biosynthesis via salvage pathway; IMP from hypoxanthine: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the purine/pyrimidine phosphoribosyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.8" evidence="2 4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297644.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001210"/>
    <dbReference type="EnsemblBacteria" id="EEZ40188">
        <property type="protein sequence ID" value="EEZ40188"/>
        <property type="gene ID" value="VDA_001210"/>
    </dbReference>
    <dbReference type="GeneID" id="57339934"/>
    <dbReference type="eggNOG" id="COG0634">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1819460at2"/>
    <dbReference type="UniPathway" id="UPA00591">
        <property type="reaction ID" value="UER00648"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052657">
        <property type="term" value="F:guanine phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004422">
        <property type="term" value="F:hypoxanthine phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032264">
        <property type="term" value="P:IMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006166">
        <property type="term" value="P:purine ribonucleoside salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005904">
        <property type="entry name" value="Hxn_phspho_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01203">
        <property type="entry name" value="HGPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0660">Purine salvage</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran" evidence="5">
        <location>
            <begin position="13"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="178" mass="20449" checksum="44D24A3E75323938" modified="2010-01-19" version="1">MKQHTIEVMISEQEVQERIKELGQQITEHYKDSKDLVLVGLLRGSFVFLADLARAINLTHEVDFMTASSYGNTMESSRDVRILKDLDDDIKGKDVLIVEDIIDTGNTLSKVREILELREPNSIRICTLLDKPERREVNVPVEWYGFVIPDEFVVGVGIDYAQKYRHLPYIGKVTLLED</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-12-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVT0</accession>
    <name>D0YVT0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">MutL protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001995</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299123.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001995"/>
    <dbReference type="EnsemblBacteria" id="EEZ40963">
        <property type="protein sequence ID" value="EEZ40963"/>
        <property type="gene ID" value="VDA_001995"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4974">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="745068at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0229">DNA integration</keyword>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyr recombinase" evidence="3">
        <location>
            <begin position="241"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="470" mass="54372" checksum="300A49B6EA684BD7" modified="2010-01-19" version="1">MARQRKLVSSEYANGDYTSVTLAVERKPVLEFVHDDNGELKPSIKERINPTMVTIPLLTDPSGALVFPANLYLHHVAQDSVELSTLNTHSQALLLFYRWLRLAGKTIYDCSSEREEGVVYGFRDFLVDNLKRDVVVDGEVTTEGIWEASTAATYVGVIIQFYEFMHVERIIRMSENFIPFEYTTKRIRKRNGKGRKRGVEKVNQHDILGHTKVGDKDFISVNTTGLLKPFKGAKPNASTSHKLTPMREDEKRIFYSYLKLDSNFESASEVKNLMLYLATEVGVRVEELVTFPASEVRYPSPELDTIPVLLSPVKNGCQTKYDKARTIQVPRKVMDALFLYKTSKARVRAESRALVKHNCLFVSHTEGRYYSPNTIEKHFESIRKNIRLTHKDWYFTVHDTRATFATHWLYEQHASRGLIFDMLLTELAELMGHEQTATTQKYIDHMNNDKHWREFAQRKNNYMKALMRNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVU1</accession>
    <name>D0YVU1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative SanA protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002022</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299200.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40990">
        <property type="protein sequence ID" value="EEZ40990"/>
        <property type="gene ID" value="VDA_002022"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2949">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1879123at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06259">
        <property type="entry name" value="YdcF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003848">
        <property type="entry name" value="DUF218"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02698">
        <property type="entry name" value="DUF218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF218" evidence="1">
        <location>
            <begin position="50"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="224" mass="25582" checksum="6024410B452A9B08" modified="2010-01-19" version="1">MKLRNIFPAFAVLCIIFVGSLLLVNRWVSAETSNQIYRDISQIPSRSVGLVLGTSKYIAKTLNPYYEYRIQAALELYKQDKINVFLLSGDNRHRSYNEPWTMKRDLLKAGVPDNEIVLDYAGFRTLDSIVRAKKVFEANHFVIITQKFHCERALFIAQNKNIDAICLAVPEPKGMAGLKLRIREVLARVKAVIDIYVLHEQPKFLGPKEPIEDPVYPSQDSNVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVY7</accession>
    <name>D0YVY7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Holo-[acyl-carrier-protein] synthase</fullName>
            <shortName evidence="8">Holo-ACP synthase</shortName>
            <ecNumber evidence="8">2.7.8.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">4'-phosphopantetheinyl transferase AcpS</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">acpS</name>
        <name evidence="10" type="ORF">VDA_001266</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>apo-[ACP] + CoA = adenosine 3',5'-bisphosphate + H(+) + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:12068"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9690"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:58343"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="EC" id="2.7.8.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the P-Pant transferase superfamily. AcpS family.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.7" evidence="8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297753.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001266"/>
    <dbReference type="EnsemblBacteria" id="EEZ40244">
        <property type="protein sequence ID" value="EEZ40244"/>
        <property type="gene ID" value="VDA_001266"/>
    </dbReference>
    <dbReference type="GeneID" id="57339845"/>
    <dbReference type="eggNOG" id="COG0736">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1893660at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008897">
        <property type="term" value="F:holo-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00101">
        <property type="entry name" value="AcpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008278">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037143">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002582">
        <property type="entry name" value="ACPS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004568">
        <property type="entry name" value="Ppantetheine-prot_Trfase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01648">
        <property type="entry name" value="ACPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56214">
        <property type="entry name" value="SSF56214"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00516">
        <property type="entry name" value="acpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00556">
        <property type="entry name" value="pantethn_trn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 8" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="4 8" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="1 8" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6 8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACPS" evidence="9">
        <location>
            <begin position="5"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ40244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="126" mass="13856" checksum="556783C6091F9C54" modified="2010-01-19" version="1">MAIVGLGTDIAEIERVAKVWQRQGLAFAERILTASELIELSQTKRPERFLAKRFAVKEAAAKALGTGIAAGVSFQDFEVGHDEFGKPLLNLTGQAQKFAQQRLVNHVHLTIADERHYAVATVILEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW15</accession>
    <name>D0YW15_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Bifunctional chorismate mutase/prephenate dehydratase</fullName>
            <ecNumber evidence="8">4.2.1.51</ecNumber>
            <ecNumber evidence="7">5.4.99.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">Chorismate mutase-prephenate dehydratase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17">p-protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="25" type="ORF">VDA_001320</name>
    </gene>
    <organism evidence="25 26">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="25 26" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="25 26">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>H(+) + prephenate = 3-phenylpyruvate + CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:21648"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:18005"/>
            <dbReference type="ChEBI" id="CHEBI:29934"/>
            <dbReference type="EC" id="4.2.1.51"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>chorismate = prephenate</text>
            <dbReference type="Rhea" id="RHEA:13897"/>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
            <dbReference type="ChEBI" id="CHEBI:29934"/>
            <dbReference type="EC" id="5.4.99.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Amino-acid biosynthesis; L-phenylalanine biosynthesis; phenylpyruvate from prephenate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Metabolic intermediate biosynthesis; prephenate biosynthesis; prephenate from chorismate: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="4.2.1.51" evidence="8"/>
    <dbReference type="EC" id="5.4.99.5" evidence="7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297856.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001320"/>
    <dbReference type="EnsemblBacteria" id="EEZ40295">
        <property type="protein sequence ID" value="EEZ40295"/>
        <property type="gene ID" value="VDA_001320"/>
    </dbReference>
    <dbReference type="GeneID" id="57339787"/>
    <dbReference type="eggNOG" id="COG0077">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1605">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1280729at2"/>
    <dbReference type="UniPathway" id="UPA00120">
        <property type="reaction ID" value="UER00203"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00121">
        <property type="reaction ID" value="UER00345"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004106">
        <property type="term" value="F:chorismate mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004664">
        <property type="term" value="F:prephenate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046417">
        <property type="term" value="P:chorismate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009094">
        <property type="term" value="P:L-phenylalanine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.59.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008242">
        <property type="entry name" value="Chor_mutase/pphenate_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036263">
        <property type="entry name" value="Chorismate_II_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036979">
        <property type="entry name" value="CM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002701">
        <property type="entry name" value="CM_II_prokaryot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010952">
        <property type="entry name" value="CM_P_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001086">
        <property type="entry name" value="Preph_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018528">
        <property type="entry name" value="Preph_deHydtase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01817">
        <property type="entry name" value="CM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00800">
        <property type="entry name" value="PDT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001500">
        <property type="entry name" value="Chor_mut_pdt_Ppr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00830">
        <property type="entry name" value="CM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48600">
        <property type="entry name" value="SSF48600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01797">
        <property type="entry name" value="CM_P_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51168">
        <property type="entry name" value="CHORISMATE_MUT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00857">
        <property type="entry name" value="PREPHENATE_DEHYDR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51171">
        <property type="entry name" value="PREPHENATE_DEHYDR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="21" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="14 25" id="KW-0413">Isomerase</keyword>
    <keyword evidence="15 25" id="KW-0456">Lyase</keyword>
    <keyword evidence="16" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="13" id="KW-0584">Phenylalanine biosynthesis</keyword>
    <keyword evidence="26" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chorismate mutase" evidence="22">
        <location>
            <begin position="2"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="Prephenate dehydratase" evidence="23">
        <location>
            <begin position="107"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="ACT" evidence="24">
        <location>
            <begin position="301"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="21">
        <location>
            <begin position="8"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="12"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="29"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Essential for prephenate dehydratase activity" evidence="20">
        <location>
            <position position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00004817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00013147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00014401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00031175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00031520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PIRSR" id="PIRSR001500-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="PIRSR" id="PIRSR001500-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS51168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="PROSITE" id="PS51171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="EMBL" id="EEZ40295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="390" mass="43824" checksum="48076958188DA945" modified="2010-01-19" version="1">MTEPTYSLDEIRLRVSQIDNQLLELLAQRRQLSLEVAKSKISTAKPVRDKAREHDLLLKLIETGKEKQLDPQYVTQLFHTIIEDSVLYQQAFLQQLINPENAQPSARIAFLGSKGSYSHLASLNYFSRKQTQLLEMSCSSFRDVINEVELGHADYGVLPIENTSSGSINEVYDLLQHTSLSIVGEITQPIEHCLLTAVETQLEAIDTLYSHPQPHQQCSEFVHQLGEIKQEYCSSTADAMKIVAELSQPNIAAIGNATSGEMYGLYSLTEHIANQEQNFTRFIVVARKAIDVTPLIPAKTTFIMSTGQSAGSLVECLLILKNHNINMAKLESRPVMGNPWEEMFYVDVEENIKSEVMQQAMEELSQVTRFIKVLGCYATENVKPTEVTID</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW32</accession>
    <name>D0YW32_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001295</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001295"/>
    <dbReference type="EnsemblBacteria" id="EEZ40270">
        <property type="protein sequence ID" value="EEZ40270"/>
        <property type="gene ID" value="VDA_001295"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="150" mass="16530" checksum="3462A7B8A1BFF9B9" modified="2010-01-19" version="1">MKLDTRTFDIPNFSKKRPIGNSSSELTPRRWMMDSLSITDILSRISSVRPVALSALPVAISKWNFFMSAVVKRLKPSLHTAFSPYSLMRNTASVLRAVAFSVILAKRVSIDLSLSSVAKCPVLLNASTFFIALVTIRYLLSLSEPPVAGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW49</accession>
    <name>D0YW49_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001331</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297868.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001331"/>
    <dbReference type="EnsemblBacteria" id="EEZ40306">
        <property type="protein sequence ID" value="EEZ40306"/>
        <property type="gene ID" value="VDA_001331"/>
    </dbReference>
    <dbReference type="GeneID" id="57339769"/>
    <dbReference type="eggNOG" id="COG3141">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1930646at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009813">
        <property type="entry name" value="Uncharacterised_YebG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038627">
        <property type="entry name" value="YebG-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07130">
        <property type="entry name" value="YebG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="100" mass="11162" checksum="147131567E29EE39" modified="2010-01-19" version="1">MAVIVKYVVERNGEEKMTFTSKSEADAYDKMLDMADEMFELLSTSDLFAEDEAKQEELSLFLAQKREEVLVALGAKKAKPAAKKKATKPELVADEQEEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWD1</accession>
    <name>D0YWD1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">tRNA(Ile)-lysidine synthase</fullName>
            <ecNumber evidence="7">6.3.4.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">tRNA(Ile)-2-lysyl-cytidine synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">tRNA(Ile)-lysidine synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">tilS</name>
        <name evidence="9" type="ORF">VDA_001375</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP + cytidine(34) in tRNA(Ile2) + L-lysine = AMP + diphosphate + H(+) + lysidine(34) in tRNA(Ile2)</text>
            <dbReference type="Rhea" id="RHEA:43744"/>
            <dbReference type="Rhea" id="RHEA-COMP:10625"/>
            <dbReference type="Rhea" id="RHEA-COMP:10670"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="ChEBI" id="CHEBI:83665"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.4.19"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the tRNA(Ile)-lysidine synthase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.19" evidence="7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001375"/>
    <dbReference type="EnsemblBacteria" id="EEZ40350">
        <property type="protein sequence ID" value="EEZ40350"/>
        <property type="gene ID" value="VDA_001375"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0037">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016879">
        <property type="term" value="F:ligase activity, forming carbon-nitrogen bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01992">
        <property type="entry name" value="PP-ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01161">
        <property type="entry name" value="tRNA_Ile_lys_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012796">
        <property type="entry name" value="Lysidine-tRNA-synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011063">
        <property type="entry name" value="TilS/TtcA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012094">
        <property type="entry name" value="tRNA_Ile_lys_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012795">
        <property type="entry name" value="tRNA_Ile_lys_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015262">
        <property type="entry name" value="tRNA_Ile_lys_synt_subst-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43033">
        <property type="entry name" value="PTHR43033"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01171">
        <property type="entry name" value="ATP_bind_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09179">
        <property type="entry name" value="TilS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11734">
        <property type="entry name" value="TilS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00977">
        <property type="entry name" value="TilS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02433">
        <property type="entry name" value="lysidine_TilS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02432">
        <property type="entry name" value="lysidine_TilS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TilS_C" evidence="8">
        <location>
            <begin position="394"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="57"/>
            <end position="62"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ40350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="467" mass="53153" checksum="3529C4B7096950AB" modified="2010-01-19" version="1">MARFLSTESLLGHQYHLGIYSKAVVAFNCLTIMLYPSFAQTLLAYPHHSKRLIIAFSGGVDSRVLLELVARFIAEHPDYQAHAVYVHHGLSAHADEWGIKCQRWAESYGISFTLERVQLETGARVSIEQVARQARYHALSTHMNLGDILLTAQHADDQIETFMLALKRGSGPTGLAAMPQWQRFVLGFHARPLLTTRRAEIVQFALDHQLDWVEDESNQDTRYDRNFLRHQIVPELEQRWPGVVAAVSRSAQLCGEQEELLAELLGQTLNQAIQSDKSLLLPSPCSKSLGFALIRQWLKSLAVVMPSLAQLQQIWSSVVHAKEDANPKLCWSQYEIRRYQGRLYVLEQWDDISSWQQTIALDQTYQLPQNLGKLTLTLQGEKALLRQPKPDETVSVRFHYQGDAIKPLGRSGSRKIKKLYQEYQVPSWMRNRTPLIFYNDKLAAAVGIFVVAEFSGTDITITLENEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWD8</accession>
    <name>D0YWD8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001409</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001409"/>
    <dbReference type="EnsemblBacteria" id="EEZ40383">
        <property type="protein sequence ID" value="EEZ40383"/>
        <property type="gene ID" value="VDA_001409"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3249">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1323839at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018642">
        <property type="entry name" value="DUF2066"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09839">
        <property type="entry name" value="DUF2066"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="388" mass="42615" checksum="DC5BCC285F060951" modified="2010-01-19" version="1">MALALSIIIRSEKYMLRILFLLLAVIALPLKAATVTDLYNAQVVLPSNDQQADTQARQQGLEQVLIKVSGQRDIAKNSYIKKAMAKPDSYISQYGYAQQQGQRVLNLAFSQSDIQKLLSSARAPIWNQRPNVLVWMVDDAHQDRQIVWDQSSNAALTDMRQMAKERGLPLTLPIGDFDDVTAISASDLWGGFADPITKASQRYHPDAILLVQEQAADNGQIALKWQLFTQNINNLAANTSAPLAGTAIGSDSSAANKMINQVADALAQKYAVQSGTKAAGDFDIAVHNIRSSDDFFSLERLLEQMTTVGSVNVVQLKGDEVIFDVNLLGSEDAFRRELMNNRHVQAYQANTQAPTPVDTATDPNQVDITATQTAPTLQIAPENTFIWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWH6</accession>
    <name>D0YWH6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Predicted metal-dependent hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_001435</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the endoribonuclease YbeY family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001435"/>
    <dbReference type="EnsemblBacteria" id="EEZ40409">
        <property type="protein sequence ID" value="EEZ40409"/>
        <property type="gene ID" value="VDA_001435"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0319">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023091">
        <property type="entry name" value="MetalPrtase_cat_dom_sf_prd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002036">
        <property type="entry name" value="YbeY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020549">
        <property type="entry name" value="YbeY_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02130">
        <property type="entry name" value="YbeY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00043">
        <property type="entry name" value="TIGR00043"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01306">
        <property type="entry name" value="UPF0054"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="8 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="4" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ40409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="78" mass="8966" checksum="60BA04FD7387AE4B" modified="2010-01-19" version="1">MEMDLLGDLVICRQVVEREAPEQNKTLTAHWAHMVVHGSLHLLGYDHIEDDEAEEMEALETEIMEKMGFPDPYAAEKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWL1</accession>
    <name>D0YWL1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">UDP-glucose lipid carrier transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_001502</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial sugar transferase family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298169.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001502"/>
    <dbReference type="EnsemblBacteria" id="EEZ40476">
        <property type="protein sequence ID" value="EEZ40476"/>
        <property type="gene ID" value="VDA_001502"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2148">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1759731at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003362">
        <property type="entry name" value="Bact_transf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017475">
        <property type="entry name" value="EPS_sugar_tfrase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02397">
        <property type="entry name" value="Bac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03025">
        <property type="entry name" value="EPS_sugtrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="72"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="100"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="231"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="Bac_transf" evidence="8">
        <location>
            <begin position="225"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ40476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="413" mass="46753" checksum="2948039D3AF27FC4" modified="2010-01-19" version="1">MNSLKTLLNNSYVCHTLGIFFVALLTYLFAGYGYKSMPDTVVNTLWLSVACYLAIAAVLPKITSYLLVERKYYILPVVVTVFILTMALVFMTRIDYSRSALINASIISFVWFYVTALIRQDSQCLTLSALPNFDASELKHNPKINLNELSQPYSIANVKGSLVVDLHKNLTAESEKFIADCSLANISVFHADSIKEMLEGKVQTRHLSENAIGTLLPNPLYMTFKRIWESLIIILSFPITLPVMAITALLIKLENPGPAMFIQERVGQGGKVFRIYKFRSMTVKAADAEDKFATQEQARVTKVGKVIRKVRIDELPQFFNVLKGDMSLIGPRPEQDSFVKQFEQEIPFYGYRHMVKPGITGWAQVVQGYTDDTESTTEKLAYDLYYIKNLSFWLDINIVFKTIRTMLTGFGAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWQ3</accession>
    <name>D0YWQ3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">2-dehydro-3-deoxyphosphooctonate aldolase</fullName>
            <ecNumber evidence="6">2.5.1.55</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">3-deoxy-D-manno-octulosonic acid 8-phosphate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">KDO-8-phosphate synthase</fullName>
            <shortName evidence="6">KDO 8-P synthase</shortName>
            <shortName evidence="6">KDOPS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Phospho-2-dehydro-3-deoxyoctonate aldolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">kdsA</name>
        <name evidence="8" type="ORF">VDA_001449</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>D-arabinose 5-phosphate + H2O + phosphoenolpyruvate = 3-deoxy-alpha-D-manno-2-octulosonate-8-phosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14053"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57693"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:85985"/>
            <dbReference type="EC" id="2.5.1.55"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Bacterial outer membrane biogenesis; lipopolysaccharide biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 6">Carbohydrate biosynthesis; 3-deoxy-D-manno-octulosonate biosynthesis; 3-deoxy-D-manno-octulosonate from D-ribulose 5-phosphate: step 2/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the KdsA family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.55" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298079.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001449"/>
    <dbReference type="EnsemblBacteria" id="EEZ40423">
        <property type="protein sequence ID" value="EEZ40423"/>
        <property type="gene ID" value="VDA_001449"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2877">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="687380at2"/>
    <dbReference type="UniPathway" id="UPA00030"/>
    <dbReference type="UniPathway" id="UPA00357">
        <property type="reaction ID" value="UER00474"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008676">
        <property type="term" value="F:3-deoxy-8-phosphooctulonate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019294">
        <property type="term" value="P:keto-3-deoxy-D-manno-octulosonic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00056">
        <property type="entry name" value="KDO8P_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006218">
        <property type="entry name" value="DAHP1/KDSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006269">
        <property type="entry name" value="KDO8P_synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21057">
        <property type="entry name" value="PTHR21057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00793">
        <property type="entry name" value="DAHP_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01362">
        <property type="entry name" value="KDO8P_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0448">Lipopolysaccharide biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAHP_synth_1" evidence="7">
        <location>
            <begin position="11"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ40423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="284" mass="31232" checksum="ED73FF2465E60B2F" modified="2010-01-19" version="1">MMEQKVVRVGDIDVANDKPFVLFGGMNVLESRDLAMKICEHYVEVTNKLGIPYVFKASFDKANRSSVHSYRGPGMDEGLKIFQELKDTFGVKIITDVHEQYQAQPVAEVVDVIQLPAFLARQTDLVEAMAKTGAVINVKKPQFMSPNQVGNIVEKFAECDNHNIILCERGVVHGYDNLVVDMLGFDVMKEASKGSPIIFDVTHSLQCRDPQGAASGGRRAQTVSLALSGVATGIAGLFMEAHPEPNNARCDGPSAFPLAQLEPFLKQVKQLDDLVKSFEHIEIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWX7</accession>
    <name>D0YWX7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Peptide transport system permease protein SapB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_001810</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298746.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001810"/>
    <dbReference type="EnsemblBacteria" id="EEZ40778">
        <property type="protein sequence ID" value="EEZ40778"/>
        <property type="gene ID" value="VDA_001810"/>
    </dbReference>
    <dbReference type="GeneID" id="57342075"/>
    <dbReference type="eggNOG" id="COG4168">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1479518at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="9"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="112"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="282"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="73"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="320" mass="35813" checksum="77509BFF26D49E97" modified="2010-01-19" version="1">MFIYTIRRLNLFIITLMILTIIGYSILRLDTNTMWSQQPFFSGWFMYLKNLAAGNLGIDINGIPVADEILAVFPATLELCFFAFLLSLIIGIPLGTIAGVRRGHFVDTVISSITLVGYSIPLFWFAMLLILLFALHLGWLPVSGRYSLLYEIHPVTGFALIDIMLSNEPYKAHAMLDAIKHLILPTLVLAMAPMTEVIRLTRASVSEVMKQNFIKVAQTKGLSTFEIVRRHGMRNAIPPIIPKLGMQFSTMMTFAMLTESIFNWPGIGRWLLDAIAAQNYIAIQAGVITVASFILLANILSDLIGAFVNPLVRKEWYAIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWY9</accession>
    <name>D0YWY9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001822</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298771.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001822"/>
    <dbReference type="EnsemblBacteria" id="EEZ40790">
        <property type="protein sequence ID" value="EEZ40790"/>
        <property type="gene ID" value="VDA_001822"/>
    </dbReference>
    <dbReference type="GeneID" id="57342062"/>
    <dbReference type="eggNOG" id="COG1737">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="992687at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901135">
        <property type="term" value="P:carbohydrate derivative metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05013">
        <property type="entry name" value="SIS_RpiR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000281">
        <property type="entry name" value="HTH_RpiR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035472">
        <property type="entry name" value="RpiR-like_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01418">
        <property type="entry name" value="HTH_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01380">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51071">
        <property type="entry name" value="HTH_RPIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH rpiR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="2">
        <location>
            <begin position="121"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="284" mass="31503" checksum="27EE63B076A70F8B" modified="2010-01-19" version="1">MNTLEKIQNNLENFSKSERKVAEVIIASPQTAIHSSIATLAKLADVSEPTVNRFCRRLDTKGFPDFKLHLAQSLANGTPYVNRNVEENDGPDAYTSKIFESTMACLDVAKNSLDPQQVNRAVDLLTQAKKISFFGLGASAAVAHDAQNKFFRFNIPIVCFDDIVMQRMSVINCSDGDVVVVISHTGRTKNLVEIARMARENGATVIGITEKDSPLERECSLSICPDVPEDTDIYMPMASRVVQMTIIDVLATGFTLRRGAGFRDNLKRVKESLKDSRFSKEPHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX82</accession>
    <name>D0YX82_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">VDA_001941</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001941"/>
    <dbReference type="EnsemblBacteria" id="EEZ40909">
        <property type="protein sequence ID" value="EEZ40909"/>
        <property type="gene ID" value="VDA_001941"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0642">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004721">
        <property type="term" value="F:phosphoprotein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="27"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="165"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="10">
        <location>
            <begin position="270"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="11">
        <location>
            <begin position="517"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="8">
        <location>
            <position position="567"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ40909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="638" mass="72497" checksum="0E04B8013D9CE760" modified="2010-01-19" version="1">MAKWNLGIKVIIHENKQKEREFRSIRLFWKMFLSLLFILTISTIATMSTAHYFNTEKIKKYTDHLMNASAPLIVDSILYSNTDSSIELNRMLSNYPEYLLVYFYDSNNKIIHAYHSMSLTPKDHAAIRTDVLKGNYAFHSAVLYDGKPIIKYSVLYDMSLFFDGVFFQVLLLITPFLLCLFMIMLYLKKRIIEPINSIIEHLPHMGSNVIDIRECKDAEEEVYLLANEIKKADSCIYHNDRKLREVNRALINKTHELNKAIKVKSEFMANMSHEIRTPMNGVVGFTQCLEEMELDNESKKYVKYIKDSASGLLSIINEILDFSRLENGNVEVSNNKFNLSEFIDEIGSVILIQANNKELTFACRIDKDLHETYIGDEGKIRQILLNLLGNAIKFTHEGSIELAVEKIQDDNSQTDCLRFRVIDTGIGISSEKQSAIFEAYQQADGSISRQFGGTGLGLAISSRLCFLLNSELNVISNESEGSEFYFDLVLESTTSSLMKTSMSESNHFDLSSYQHKHIVVAEDSKVNQKLIETLLKTMKVTNIHIVNDGVEVTSYIEKNGADLVLMDCQMPRMGGIEATQAIRNMSSIEQPIIIALTANVLPEEKENCFRAGMNDYLPKPIVKQALFIALRNALASSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXD2</accession>
    <name>D0YXD2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001672</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40645">
        <property type="protein sequence ID" value="EEZ40645"/>
        <property type="gene ID" value="VDA_001672"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="18"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="52" mass="5964" checksum="E09F32893B671B7C" modified="2010-01-19" version="1">MAIARYITLGMKELNGEFIVWLSLSAFILAAATLIIRAGHHYWPYKEDDSHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXJ9</accession>
    <name>D0YXJ9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001713</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298563.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40684">
        <property type="protein sequence ID" value="EEZ40684"/>
        <property type="gene ID" value="VDA_001713"/>
    </dbReference>
    <dbReference type="GeneID" id="57342202"/>
    <dbReference type="eggNOG" id="ENOG5033A6M">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2003389at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="65" mass="7837" checksum="4F3ECAD47D08E036" modified="2010-01-19" version="1">MTQTHELTQQEKDAIEELAINRVNYMNSDQVLVEAIDQKVHNMEEHLKAYFHERFQFHHTKAQQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXK4</accession>
    <name>D0YXK4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative efflux (PET) family transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001718</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298573.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40689">
        <property type="protein sequence ID" value="EEZ40689"/>
        <property type="gene ID" value="VDA_001718"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1289">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1338660at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010019">
        <property type="entry name" value="Integral_membrane_YccS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010020">
        <property type="entry name" value="Integral_membrane_YCCS_YHJK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032692">
        <property type="entry name" value="YccS_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12805">
        <property type="entry name" value="FUSC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01666">
        <property type="entry name" value="YCCS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01667">
        <property type="entry name" value="YCCS_YHJK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="140"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="443"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="467"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="491"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="domain" description="FUSC-like" evidence="2">
        <location>
            <begin position="71"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="721" mass="81732" checksum="6B428077FB81E213" modified="2010-01-19" version="1">MQTRHLHFTLRRYWANDRINYCIRVLIAMIGVVFPCWYLNATSEVTPLILGIIAAALAETDDNLTGRLKALATTLICFLVASVSIEVLFDYPIFFALGLFSSTFGFIMLGAMGPRYASIAFASLLLAVYTMLGADSSVNLWYQPMLLLGGAFWYGLLSLAWHILWPNQPVQQNLAHVFSQLATYLDSKSQLFEPIADLQPQPLRLDAAHNNAKVVAALNGAKATLLHRARRGQPHTTGDRFLKIYFMAQDIHERVSSSHYRYQDLAATFQRSDVLFRFQRLLRAQAMACRGIAKALAIGKPYQHLEITEKTLDELRESINYLKAQNNPQWRLLLTQLDYLFSNLATVERQLANISNPDATVTDETELADNEAHSIPDLWRRITSQLNPQSLLFRHALRMAIALTVGYGCIQFLHLERGYWILLTTLFVCQPNYSATRQKLVQRVIGTLGGLLAGIPLLYLFPGQEGQLVLMILAGVLFFAFRMVRYDLATAFITLLVLFCFNQLGEGFAVILPRLGDTLLGCFLAVIAVSYIFPDWESHRLHKVMASSVNANREYLGQIIAQYRLGKRDCLNYRVARRNAHNTDAQLSTAISNMLAEPGRYRMATNESFRFLTLNHAMLSYISALGAHRTQLEDNETYHLVSQAYRSINEHLESLTLQLEQNKPMAMPETDSALEQSLSQWRDDDCESTKMVLQQLHLIQRMLPELHSLTNKLTVRTNISK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXM1</accession>
    <name>D0YXM1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative hemolysin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001762</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298648.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001762"/>
    <dbReference type="EnsemblBacteria" id="EEZ40730">
        <property type="protein sequence ID" value="EEZ40730"/>
        <property type="gene ID" value="VDA_001762"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0204">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3176">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="218801at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07986">
        <property type="entry name" value="LPLAT_ACT14924-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045746">
        <property type="entry name" value="ACT14924-like_Acyltransf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19576">
        <property type="entry name" value="Acyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PlsC" evidence="1">
        <location>
            <begin position="75"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="587" mass="65987" checksum="E2BC6D223D0D0D58" modified="2010-01-19" version="1">MTELQPFSLPKKTPLGLFERSMEHLTGLSQLQALYEQRPQALSSAEFLRYTLRSLNVRSRYLRKDFAQLPKTGPVVIVANHPLGGLEGVILASLILAHRPDLKLFANELLYSIPELRDIFIPVDVFSTTKAKVTNSNALNEGREHLKNGGVLLVFPAGAVSTQQADNVIDDLPWRHSAAKLAIETGAIVCPVYIQGQNSRAFYRAKKIHSLLGTCMLGRELLNKSGTCLGVAVGDLVKPATLYHYKTIPQVTAYLRMLTYSLEQSIKPRPETLANTYSNTISLPIDSRKLLVDIEHLPEEAKLISQGGMSAYIANVQQIPNLILEIGRLRESVFRAVGEGTGQSIDTDQFDKTYLHLFVWDHKDNKLVGAYRLGLVDKILHQGNLATLYTYSLFRYDNTLLKQFGPSIELGRSIIAKKYQRSPTALALLWRGICTFISRNPKYTHLFGPVTISNRYSKVSQQMMGEVLSREFGDTALSRCVQPRSPFQSQHYTWFNDSIHNLKQLDHFISQQENEASGIPVLLRQYLNIGGKVIAFNVDHDFQDALDGLLVVDLRDVSQRQLAKYMGTHAATSYLSYHKAHNDTYNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXS2</accession>
    <name>D0YXS2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ATP-binding protein Uup</fullName>
            <ecNumber evidence="5">3.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">uup</name>
        <name evidence="9" type="ORF">VDA_002085</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="5">Associates with ribosomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.-" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299386.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002085"/>
    <dbReference type="EnsemblBacteria" id="EEZ41053">
        <property type="protein sequence ID" value="EEZ41053"/>
        <property type="gene ID" value="VDA_002085"/>
    </dbReference>
    <dbReference type="GeneID" id="57341800"/>
    <dbReference type="eggNOG" id="COG0488">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1112046at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00848">
        <property type="entry name" value="Uup"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032524">
        <property type="entry name" value="ABC_tran_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032781">
        <property type="entry name" value="ABC_tran_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043686">
        <property type="entry name" value="Uup"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037118">
        <property type="entry name" value="Val-tRNA_synth_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16326">
        <property type="entry name" value="ABC_tran_CTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12848">
        <property type="entry name" value="ABC_tran_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="1"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="320"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="546"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="546"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <begin position="352"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="642" mass="72821" checksum="A53C7FD61EFF3A32" modified="2010-01-19" version="1">MALINISNAQLAYGDHPLLDKAEFVLQPNERVCLVGRNGAGKSTLMKVIAGEILLDDGSIQRQSELVVSRLEQDPPRDAEGTVFDYVAEGLADVGTLLREYHQQLDLITADPSESNINKLARIQEKLDHANAWQIDTRITQVLESLNLTANTLLTDLSGGWQRKAALARALVCDPDILLLDEPTNHLDVTTIEWLEGFLKEFRGSIIFISHDRAFIRSMATRIVDLDRGQLSSFPGDYEKYLDEKEEQLRVEAEQNAEFDKKLAQEEVWIRQGIKARRTRNEGRVRALKQLRNERSERREVQGKADMQLQEAKRSGKIVFEAENISHSFGDQAIIKDFSFNVMRGDRIALIGPNGCGKSTLLKILLGQLENSGGKFHCGTKLEVAYFDQYREILDPEKTVMDNLADGKQEVVVNGKSRHALGYLQDFLFHPRRARTPVKALSGGEKNRLLLAKLFLKPNNLLVLDEPTNDLDIETLELLEEILANYQGTLLLVSHDRQFVDNTVTTSWIFEGNGVVNEYVGGYHDAQSQRENSLANIAKKEAEERELAKKKEEQQKQRQANRQRSSKKLSYKLQLELDELPAKIEQLENDIAELQEKINDPGFFADVKNDTQAVLTLLAEKEQAFEVAFERWEELEAMQKES</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXS9</accession>
    <name>D0YXS9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glycine betaine transporter OpuD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_002092</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41060">
        <property type="protein sequence ID" value="EEZ41060"/>
        <property type="gene ID" value="VDA_002092"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1292">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071705">
        <property type="term" value="P:nitrogen compound transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000060">
        <property type="entry name" value="BCCT_transptr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30047">
        <property type="entry name" value="PTHR30047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02028">
        <property type="entry name" value="BCCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="85"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="179"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="222"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="248"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="308"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="339"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="389"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="429"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="459"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="497" mass="56731" checksum="87C9C2EC68639107" modified="2010-01-19" version="1">MIKIKLSGSRNWLPFFLYGGILLLSFMFLIFPNQAVFILSRISNKLSVILARPILITTSLVVILCFILALFPIGKTRLGNSQPDYSYISWITMVFTTGMGSGLVFWGIAEPAYHYLFFNKLTVTESHSVSNVLAITYFHWGLHAWSIYTIVALSYAWFRYIRNRDLSLTSPFIEQSNNSIFFDIINIITVFTIIFSVAGAFANSVSLIQDGLNLTANTMKGFNSRIIIVILISLFFCISSFTSIKKGIRILSLLNVMLMLTLAVTVFFTNDVKNILHIFMNSIKDYILLLPKLSFQLNEKSQQWSVDWTINYFIWWCAWAPFVGIFLAKISKGRTVRQFILSVIFIPTLTSMIWFSIYSGSALIKYSEPVLSATKKDFTYGLFAFYEQLPFSTFLSTSSIILLSLFIITSIDSSVNTIDTLIKNDKRRITLLYCLLISSLTIILTYYNDINLNKQIAIIGAIPFMIIIVIQIYTFIVDVIFYISLKDRIKNNPIKSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXV0</accession>
    <name>D0YXV0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002113</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002113"/>
    <dbReference type="EnsemblBacteria" id="EEZ41081">
        <property type="protein sequence ID" value="EEZ41081"/>
        <property type="gene ID" value="VDA_002113"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5473">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="124"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="150"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="192"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="249"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="273" mass="29640" checksum="C2E3B2B334CE5D81" modified="2010-01-19" version="1">MTKSFHVGGSIEKAVKGEVELKAVDVLQEAWKVTAKHFFRFLPAIIGLFVAQVALLLLGLKVQLGDPNIFFNAFITGEGITPDLMQSALMANFWSDVLIAPLYAGVSLMALNHAVGLPTKPGQIVRGFSFTLVSIITMLLTSSIQGIGNTIFPLVGLFLTMALSLAMTLVCEKRVTPLKAIQYSFMATVRKLMPMTAIYLVILIMMFISMATAGLGLLWTLPFFFNVKAIIYRNMFGITLQVMTIEGDNKDSTPPSSSPENGSTSSQGNTFDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXV9</accession>
    <name>D0YXV9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Formate dehydrogenase-O iron-sulfur subunit</fullName>
            <ecNumber evidence="5">1.2.1.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_002122</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.2.1.2" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299491.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002122"/>
    <dbReference type="EnsemblBacteria" id="EEZ41090">
        <property type="protein sequence ID" value="EEZ41090"/>
        <property type="gene ID" value="VDA_002122"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0437">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1762646at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12838">
        <property type="entry name" value="Fer4_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="4"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="49"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="80"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="207" mass="22121" checksum="15EE04A11F292E23" modified="2010-01-19" version="1">MARMKFLCDTKRCIECNGCVTACKNANSEAVGWGIQRRRVVTLNDGLPGETSISVACMHCSDAPCMAVCPADCFSQTEDGIVQHNKDLCIGCGYCLFACPFGAPQFPKQQAFAERGKMDKCTYCSGGPNTEPGSEKERLLYGANRIAEGKLPMCASMCSTKSLLAGDAEKISEIYSKRVAARGAKDAGWASTAADELAMDASKVRKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY02</accession>
    <name>D0YY02_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002165</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299574.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002165"/>
    <dbReference type="EnsemblBacteria" id="EEZ41133">
        <property type="protein sequence ID" value="EEZ41133"/>
        <property type="gene ID" value="VDA_002165"/>
    </dbReference>
    <dbReference type="GeneID" id="57341694"/>
    <dbReference type="eggNOG" id="ENOG502ZWH8">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="950811at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021974">
        <property type="entry name" value="DUF3581"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12119">
        <property type="entry name" value="DUF3581"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="239" mass="27070" checksum="2937F1A0E58B275A" modified="2010-01-19" version="1">MFLDSYYSDHNDAFSFTRQQASHFAKKVAGDFNPIHDEDNKRFCVPGDLLFSVFLAKEGLSQKMRFEFAGMISDGIALTFYQKSDNDISVKDEKCKEYMHVTRSGLTTTDETLIAQITKNYVQFSGMNFPHIMVPLMKSKEIMINPARPLVVYESMELDFTRLDLKAPTVELLDSEIDADGKRGSVTLNFCFKEDGEIVGTGKKRMVMSGLRPYCQDGIDDLVSRFLARKDAFLTEVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY28</accession>
    <name>D0YY28_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">GTP cyclohydrolase II</fullName>
            <ecNumber evidence="7">3.5.4.25</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_002191</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; riboflavin biosynthesis.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.25" evidence="7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002191"/>
    <dbReference type="EnsemblBacteria" id="EEZ41159">
        <property type="protein sequence ID" value="EEZ41159"/>
        <property type="gene ID" value="VDA_002191"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0807">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00275"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003935">
        <property type="term" value="F:GTP cyclohydrolase II activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00641">
        <property type="entry name" value="GTP_cyclohydro2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032677">
        <property type="entry name" value="GTP_cyclohydro_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000926">
        <property type="entry name" value="RibA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036144">
        <property type="entry name" value="RibA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00925">
        <property type="entry name" value="GTP_cyclohydro2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142695">
        <property type="entry name" value="SSF142695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0686">Riboflavin biosynthesis</keyword>
    <feature type="domain" description="GTP_cyclohydro2" evidence="6">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="147" mass="16498" checksum="A9BD802A5BBC6B3F" modified="2010-01-19" version="1">MHSECLTGDVFHSSRCDCGEQLDETITKMGELGGVLLYLRQEGRGIGLYNKIDAYKLQSEGMNTYEANNHLGFPDDLRDFSEAAQMLKALGLEEIRLITNNPKKIRELEENGIKIAEVVGTKAHIKDGNENYLKAKVSHGHHRLDVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY45</accession>
    <name>D0YY45_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Trimethylamine-N-oxide reductase</fullName>
            <ecNumber evidence="4">1.7.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">VDA_002208</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
            <dbReference type="ChEBI" id="CHEBI:60539"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.7.2.3" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299651.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002208"/>
    <dbReference type="EnsemblBacteria" id="EEZ41176">
        <property type="protein sequence ID" value="EEZ41176"/>
        <property type="gene ID" value="VDA_002208"/>
    </dbReference>
    <dbReference type="GeneID" id="57341648"/>
    <dbReference type="eggNOG" id="COG0243">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="88184at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043546">
        <property type="term" value="F:molybdopterin cofactor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050626">
        <property type="term" value="F:trimethylamine-N-oxide reductase (cytochrome c) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02793">
        <property type="entry name" value="MopB_CT_DMSOR-BSOR-TMAOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006658">
        <property type="entry name" value="BisC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041954">
        <property type="entry name" value="CT_DMSOR/BSOR/TMAOR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041460">
        <property type="entry name" value="Molybdopterin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006657">
        <property type="entry name" value="MoPterin_dinucl-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006656">
        <property type="entry name" value="Mopterin_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006655">
        <property type="entry name" value="Mopterin_OxRdtase_prok_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019546">
        <property type="entry name" value="TAT_signal_bac_arc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00384">
        <property type="entry name" value="Molybdopterin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18364">
        <property type="entry name" value="Molybdopterin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01568">
        <property type="entry name" value="Molydop_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="SSF50692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00509">
        <property type="entry name" value="bisC_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01409">
        <property type="entry name" value="TAT_signal_seq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00490">
        <property type="entry name" value="MOLYBDOPTERIN_PROK_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="9 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-0574">Periplasm</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018678" description="Trimethylamine-N-oxide reductase" evidence="10">
        <location>
            <begin position="41"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="domain" description="Molybdopterin_N" evidence="13">
        <location>
            <begin position="54"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="Molybdopterin" evidence="11">
        <location>
            <begin position="98"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="domain" description="Molydop_binding" evidence="12">
        <location>
            <begin position="686"/>
            <end position="807"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF18364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEZ41176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="843" mass="93368" checksum="AD450978C7260A83" modified="2010-01-19" version="1">MATQVNNKGISRRRFLSGLAVASAASVVGTSLLAPRKAMAATDAKANFTGEVLSGSHWGAFRAKVVDGVWVETVPFEKDPHPTSMLEGVREVVYNPARVKYPMVRIDWLKHGYKSDTTQRGNNRFVRVPWSQALDFFHHELNRVQETYGPSALYAGHTGWQSVGKLHSAGTMMMRAIGLHGTFLAKAGDYSTGAAQVILPYVAGAMEVYEQQTSWPLVLEHSDTIVIWGSDPIKNLQVGWLVPDHSVYGYWQQLAEKVKNKEIKVIHVDPVRNETMKFVGGEQVAVNPQTDIPLMLAIAHTLYSENLYNKEFIADYTTGFDKFMPYVLGKTDGVEKTPEWAAKITGIPADDIRALARQMASGRTQLIGGWCLQRMQHGEQWAWMLVVIAAMLGQIGLPGGGFGFGWHYNDAGTITSAGPLMSGFSGVTGVEPIFNGSYKGYAKAIPVARFVDCIANPGKKIQWNGHDITYPYMKMAIFSGNNPFHHHQDRNKMIKAWTNLETVVSVEHQWTATCRFADIVLPATTTYERDDIEQFGNHSNKGIVALRKIVEPMFESKDDFDIFRDLCRRFNREEAFTGGKEKMEWVEEIYNGARLQGRGLGVRMPNFTKFWAGDGFIEFPAGKEWVRHESFRNEPDLEPLGTASGLIEIYCKTIADMGYDDCQGHPMWFEKAERSHGGPLSDKFPLHLQSCHPNHRLHSQLCSSTDFRATYTVADREPVYISTKDAAARGIKSGDLVRVFNDRGQVLAGAVVTDDYSAGVCRIHEGAWYSPLDGGKAGTICTYGDPNVLTLDIGTSKLAQATSAHTALVDIEKYTGPVPAVTGFGGPIYVTDIDPLFPAMDKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYF2</accession>
    <name>D0YYF2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Aminotransferase</fullName>
            <ecNumber evidence="4">2.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_002315</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.-" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299847.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002315"/>
    <dbReference type="EnsemblBacteria" id="EEZ41283">
        <property type="protein sequence ID" value="EEZ41283"/>
        <property type="gene ID" value="VDA_002315"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1448">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="417859at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901605">
        <property type="term" value="P:alpha-amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000796">
        <property type="entry name" value="Asp_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11879">
        <property type="entry name" value="PTHR11879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00799">
        <property type="entry name" value="TRANSAMINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="5">
        <location>
            <begin position="27"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="396" mass="43405" checksum="318F725D531AF0AA" modified="2010-01-19" version="1">MFEKISAAPADPILGLTEEFKNDPRVEKINLGVGIYKNEQGQTPVLATVKKAEAILLDKETTKSYLSIPGTPEYGLAVQQLLFGADAKLIADKRTKTAQAPGGTGALRVGAEFIKRQLGDVTVWISNPTWANHHGVFGAAGLEIKTYTYYNPETKDIDFPATLADLNQAKAGDIVLFHGCCHNPTGIDPTAEQWQQLADLCKEKQLLPMFDFAYQGFASGVEEDAQGLRLFAEQLDELLIASSFSKNFGLYNERVGAFTLVAKNAQEAEVAFSQVKSIARVIYSNPPAHGAAIVTVILNDPALRAEWEQEVAEMRDRIQEMRTLFVDTLKSLGIDRDFSFIEQQNGMFSFSGLNKEQVQRLKDEFGIYIVGSGRISVAGMTKANMMPLCQGIAAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYG2</accession>
    <name>D0YYG2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcription regulator MarR family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002325</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299874.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002325"/>
    <dbReference type="EnsemblBacteria" id="EEZ41293">
        <property type="protein sequence ID" value="EEZ41293"/>
        <property type="gene ID" value="VDA_002325"/>
    </dbReference>
    <dbReference type="GeneID" id="57341490"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1744037at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01047">
        <property type="entry name" value="MarR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="4"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="163" mass="18459" checksum="9006727FA9AC4EAE" modified="2010-01-19" version="1">MEKHEEVLIALRQIIRAIDLHSRKLNKNAGLTGPQLVLMRAIRDSGTEITIRQLSNNTNMSQATATTILDRLESRELVVRQRSQLDKRKVHAHLTEKGKALLEKAPMPLQDSFISQFQTLEDWEQSLLLSSVQRISSMMNAEHLDVAPLLEVGSITKHDSSEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYN2</accession>
    <name>D0YYN2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="14 15">Multifunctional fusion protein</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="14">Indole-3-glycerol phosphate synthase</fullName>
                <shortName evidence="14">IGPS</shortName>
                <ecNumber evidence="14">4.1.1.48</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="15">N-(5'-phosphoribosyl)anthranilate isomerase</fullName>
                <shortName evidence="15">PRAI</shortName>
                <ecNumber evidence="15">5.3.1.24</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="14" type="primary">trpC</name>
        <name evidence="15" type="synonym">trpF</name>
        <name evidence="18" type="ORF">VDA_002395</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Bifunctional enzyme that catalyzes two sequential steps of tryptophan biosynthetic pathway. The first reaction is catalyzed by the isomerase, coded by the TrpF domain; the second reaction is catalyzed by the synthase, coded by the TrpC domain.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 14">
            <text>1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate + H(+) = (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:23476"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:58613"/>
            <dbReference type="ChEBI" id="CHEBI:58866"/>
            <dbReference type="EC" id="4.1.1.48"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 15">
            <text>N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:21540"/>
            <dbReference type="ChEBI" id="CHEBI:18277"/>
            <dbReference type="ChEBI" id="CHEBI:58613"/>
            <dbReference type="EC" id="5.3.1.24"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 15">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 3/5.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 14">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 4/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the TrpC family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the TrpF family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">In the C-terminal section; belongs to the TrpF family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">In the N-terminal section; belongs to the TrpC family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.48" evidence="14"/>
    <dbReference type="EC" id="5.3.1.24" evidence="15"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002395"/>
    <dbReference type="EnsemblBacteria" id="EEZ41363">
        <property type="protein sequence ID" value="EEZ41363"/>
        <property type="gene ID" value="VDA_002395"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0134">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0135">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00042"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004425">
        <property type="term" value="F:indole-3-glycerol-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004640">
        <property type="term" value="F:phosphoribosylanthranilate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00331">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00405">
        <property type="entry name" value="PRAI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00134_B">
        <property type="entry name" value="IGPS_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00135">
        <property type="entry name" value="PRAI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045186">
        <property type="entry name" value="Indole-3-glycerol_P_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013798">
        <property type="entry name" value="Indole-3-glycerol_P_synth_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001468">
        <property type="entry name" value="Indole-3-GlycerolPSynthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001240">
        <property type="entry name" value="PRAI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22854">
        <property type="entry name" value="PTHR22854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00218">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00697">
        <property type="entry name" value="PRAI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00614">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 14" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 14" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="8 14" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="15 18" id="KW-0413">Isomerase</keyword>
    <keyword evidence="11 14 18" id="KW-0456">Lyase</keyword>
    <keyword evidence="12" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 14" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="IGPS" evidence="16">
        <location>
            <begin position="7"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="PRAI" evidence="17">
        <location>
            <begin position="259"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00009847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00025592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EEZ41363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="471" mass="52513" checksum="7BBC0DA560C3C165" modified="2010-01-19" version="1">MTMETVLQKIVADKRLWVEARKKLQPLTGFKSAVKTSDRSFYQALKQQPVAFILECKKASPSKGLIRADFNLDAIAKVYRRYASAISVLTDEKYFQGQFEFITHVREQVEQPVLCKDFMIDPYQVYLARYYQADAILLMLSVLDDETYQQLSTLAHQLGMGVLTEVSTEDELQRAIDLKATVVGINNRNLRDLSIDLNRTKQLAPKLPNGVTVISESGIYNNQQVRELAQYADGFLIGSALMAENDLELAVRKVILGENKVCGLTHSDDASYAYQSGAYYGGLIFAKASPRAISNEQARMVISGAPLKYIGVFQNQTSEEIVQTVKALGLYGVQLHGQEDTAYIAELTKQLQESQITCQLWKAYGIAGEQLPDFLPDVDRHLLDCKVGQQLGGTGQRFDWSLLDSLSEQQKSQLMIAGGINPSNAFIAIQIHCAGLDLNSGVEIKPGQKDPQKLQAAFAAIRQIKENRHYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYN6</accession>
    <name>D0YYN6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein yciI</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002399</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the YciI family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300022.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002399"/>
    <dbReference type="EnsemblBacteria" id="EEZ41367">
        <property type="protein sequence ID" value="EEZ41367"/>
        <property type="gene ID" value="VDA_002399"/>
    </dbReference>
    <dbReference type="GeneID" id="57341399"/>
    <dbReference type="eggNOG" id="COG2350">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1780176at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005545">
        <property type="entry name" value="YCII"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03795">
        <property type="entry name" value="YCII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YCII" evidence="2">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="99" mass="11053" checksum="A0D09208FC0FE157" modified="2010-01-19" version="1">MWYVIFSQDVENSLERRMSVREKHLARLKDLQNEGRLLVAGPMPAIDDENPGEAGFTGSTVIADFASLEDAQAWADADPYIDAGVYEKVIVKPFKKVLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYR6</accession>
    <name>D0YYR6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002429</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41397">
        <property type="protein sequence ID" value="EEZ41397"/>
        <property type="gene ID" value="VDA_002429"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3318">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011978">
        <property type="entry name" value="UPF0149"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036255">
        <property type="entry name" value="YgfB-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03695">
        <property type="entry name" value="UPF0149"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101327">
        <property type="entry name" value="SSF101327"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02292">
        <property type="entry name" value="ygfB_yecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="161" mass="17655" checksum="42D3ABD437846484" modified="2010-01-19" version="1">MAAAPNILDPAEWLAFLWGGEEVSPFTTHEELEAYANAIVGIWNDARAALLAGTWQWPEGCALDDAQLVTEETREFTEGMLQGWQLARDDWETIMPEDSEDNALLGGVLLSISLLFDPENALAVLSQEGADALAQFEEIFKAVPTMLCGLTQRAQTLAEDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYW1</accession>
    <name>D0YYW1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8 10">Thymidine kinase</fullName>
            <ecNumber evidence="2 8 10">2.7.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">tdk</name>
        <name evidence="12" type="ORF">VDA_002474</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8 10">
            <text>ATP + thymidine = ADP + dTMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19129"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17748"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:63528"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.21"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8 11">Belongs to the thymidine kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.21" evidence="2 8 10"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300162.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002474"/>
    <dbReference type="EnsemblBacteria" id="EEZ41442">
        <property type="protein sequence ID" value="EEZ41442"/>
        <property type="gene ID" value="VDA_002474"/>
    </dbReference>
    <dbReference type="GeneID" id="57341305"/>
    <dbReference type="eggNOG" id="COG1435">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1279539at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004797">
        <property type="term" value="F:thymidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00124">
        <property type="entry name" value="Thymidine_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001267">
        <property type="entry name" value="Thymidine_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020633">
        <property type="entry name" value="Thymidine_kinase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11441">
        <property type="entry name" value="PTHR11441"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00265">
        <property type="entry name" value="TK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF035805">
        <property type="entry name" value="TK_cell"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00603">
        <property type="entry name" value="TK_CELLULAR_TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 10" id="KW-0237">DNA synthesis</keyword>
    <keyword evidence="6 8 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 8 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Proton acceptor" evidence="8 9">
        <location>
            <position position="88"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="9"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="87"/>
            <end position="90"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR035805-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ41442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="192" mass="21934" checksum="6DA3D4AF3220AE0E" modified="2010-01-19" version="1">MAQMYFYYSAMNAGKSTTLLQSSFNYRERGMTPLIFTAAIDDRYGKGKVSSRIGLQEDAELFNNADDLYAQITDIHNEKKIDCVLIDECQFLTKDQVYQLTEVVDKLHIPVLCYGLRTDFRGELFEGSRYLLSWADKLVELKTICHCGRKANMVIRQDETGRAIADGDQVEIGGNDRYVSVCRTHYKEALGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYW2</accession>
    <name>D0YYW2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Na(+)/H(+) antiporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_002475</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002475"/>
    <dbReference type="EnsemblBacteria" id="EEZ41443">
        <property type="protein sequence ID" value="EEZ41443"/>
        <property type="gene ID" value="VDA_002475"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1757">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018461">
        <property type="entry name" value="Na/H_Antiport_NhaC-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03553">
        <property type="entry name" value="Na_H_antiporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="47"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="130"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="188"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="220"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="286"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="327"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="367"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="408"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="438"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="490"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="515"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="domain" description="Na_H_antiporter" evidence="7">
        <location>
            <begin position="179"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ41443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="545" mass="58115" checksum="185C5E7F391D0F77" modified="2010-01-19" version="1">MTVDLQPGSVVIEIMNFVDYSHSLVSILPPLVALSLAILTRRVLISLGAGIVLGALLLTDFSLGNTFSYLKQTATELFVVDGDLNYSNLSILLFLVLLGMTTALLTLSGGTRAFAEWAQTKIKSKRGAKLLAAFLGIFIFVDDYFNSLAVGAIARPVTDRFYVSRAKLAYVVDSTAAPMCVIMPASSWGAYIITLIGGILVSHGVTEYSPLSAFMTLAPMNFYAIFALAMVFVVAWFQWDVGPMKKHEMAASHGRGFDEGDSLDEAKALDEELEIKESDKGRVGDLVWPILVLIFATFFFMIYTGNEGLAAAGKPFDILGAFENTNVGKSLVLGGTLGLICALIPVLRQRLPMADVTSTLWIGAKSMFGAILILLFAWSIGSVIGDIQTGKYLSTLVQGNINPMLLPVILFCLSGIMAFSTGSSWGTFGIMLPIAGDLAGATDITLMLPMLAGVLAGAVFGDHCSPISDTTILSSTGARCHHIDHVATQLPYALSVAFVSAVGFLVLGITDSLPVSFLAATLTFVVMCFGLSWWSRRPVSSTSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYX3</accession>
    <name>D0YYX3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DinG family ATP-dependent helicase YoaA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_002486</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300184.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002486"/>
    <dbReference type="EnsemblBacteria" id="EEZ41454">
        <property type="protein sequence ID" value="EEZ41454"/>
        <property type="gene ID" value="VDA_002486"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1199">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="679382at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016818">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006555">
        <property type="entry name" value="ATP-dep_Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045028">
        <property type="entry name" value="DinG/Rad3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014013">
        <property type="entry name" value="Helic_SF1/SF2_ATP-bd_DinG/Rad3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472">
        <property type="entry name" value="PTHR11472"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13307">
        <property type="entry name" value="Helicase_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00491">
        <property type="entry name" value="HELICc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51193">
        <property type="entry name" value="HELICASE_ATP_BIND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="4">
        <location>
            <begin position="11"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="652" mass="72289" checksum="C926D659114E8539" modified="2010-01-19" version="1">MIAKFFAPGGALAKAIPGFQARQPQIEMATAVANAIKQQGQLVVEAGTGTGKTFAYLIPALASGKKTIISTGSKSLQEQLFHRDLPLMTEAIGFTGPVALLKGRANYLCLDRLARQTVESHGVHTDPTQLTQLVKIRSWSSASKTGDLGECDELAEDSPIIPLITSTNDNCLGRECPYYDDCFVMKARKKAMEADVVVVNHHLFLADLAIKETGFGELIPEADNFIFDEAHQIPDIASQYFGQSFTSRQVQDLAKDIEIGYRTEAKDMRQLQKTADRLAQAAFDLRIILGDPGFRGNWREAVKVPAVSRELTRLQDALELTYDVLKLCLGRSQLLDTAFERATLLKGKLNRLCDTSITGYSYWYECTPRHFSLNITPLSVADKFHEQIEQKKGAWIFTSATLAVDGDFSHFSQRLGLKPIEQFSLESPFDYQQQALLCVPRFLPEPNSYGLADKLVTMLTPLIQSNGGRCFFLCTSHQMVRDLAEGFRQSLDLPVLAQGEMTKQKLLAEYLELGNALLIATGAFWEGIDVRGQALSCVIIDKLPFTAPDDPLLKARIEDCQVRGGDPFAQVQIPDAVITLKQGVGRLIRDEQDKGVLVICDNRLVTRPYGAVFLRSLPPIPRTRSVDEVENFLSLLTNNEVEQVNDNQHSEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYY7</accession>
    <name>D0YYY7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 10">Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex</fullName>
            <ecNumber evidence="5 10">2.3.1.61</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">2-oxoglutarate dehydrogenase complex component E2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">VDA_002500</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 10">E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>(R)-N(6)-dihydrolipoyl-L-lysyl-[2-oxoglutarate dehydrogenase complex component E2] + succinyl-CoA = (R)-N(6)-(S(8)-succinyldihydrolipoyl)-L-lysyl-[2-oxoglutarate dehydrogenase complex component E2] + CoA</text>
            <dbReference type="Rhea" id="RHEA:15213"/>
            <dbReference type="Rhea" id="RHEA-COMP:10581"/>
            <dbReference type="Rhea" id="RHEA-COMP:10582"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="ChEBI" id="CHEBI:83120"/>
            <dbReference type="EC" id="2.3.1.61"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
        <text evidence="10">Binds 1 lipoyl cofactor covalently.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Amino-acid degradation; L-lysine degradation via saccharopine pathway; glutaryl-CoA from L-lysine: step 6/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.61" evidence="5 10"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300206.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002500"/>
    <dbReference type="EnsemblBacteria" id="EEZ41468">
        <property type="protein sequence ID" value="EEZ41468"/>
        <property type="gene ID" value="VDA_002500"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0508">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1626282at2"/>
    <dbReference type="UniPathway" id="UPA00868">
        <property type="reaction ID" value="UER00840"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045252">
        <property type="term" value="C:oxoglutarate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004149">
        <property type="term" value="F:dihydrolipoyllysine-residue succinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033512">
        <property type="term" value="P:L-lysine catabolic process to acetyl-CoA via saccharopine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004167">
        <property type="entry name" value="PSBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006255">
        <property type="entry name" value="SucB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02817">
        <property type="entry name" value="E3_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47005">
        <property type="entry name" value="SSF47005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01347">
        <property type="entry name" value="sucB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51826">
        <property type="entry name" value="PSBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 14" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9 10" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 10" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="12">
        <location>
            <begin position="2"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="13">
        <location>
            <begin position="112"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="88"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00019511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEZ41468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="403" mass="44360" checksum="092699970B5193B0" modified="2010-01-19" version="1">MTIEILVPDLPESVADATVATWHKKPGDMVERDEVLVDIETDKVVLEVPAPESGVLEAIIEDEGTTVLTKQLIGRLKVNAVAGEPTVDVPAGAEASPNKRNTAALSEENSEALSPAVRRLLAEHNLEAKQVPGTGVGGRITREDVDNYLKNKQPVAVVNTTVEVKEAPLSHRSEKRVPMTRLRKRVTERLLEAKNSTAMLTTFNEVNMKPIMNIRKQYKDVFEERHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDIVYHNFFDVSIAVSTPRGLVTPVLRDCDKLSLAEIEKGIRDLAIKGRDGKLTVDELTGGNFTVTNGGVFGSLMSTPIINPPQAAILGMHKIQDRPMAVDGKVEILPMMYLALSYDHRLVDGRESVGFLVTIKELLEDPTRLLLDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ09</accession>
    <name>D0YZ09_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 8">Adenylate kinase</fullName>
            <shortName evidence="6">AK</shortName>
            <ecNumber evidence="6 8">2.7.4.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">ATP-AMP transphosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">ATP:AMP phosphotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Adenylate monophosphate kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">adk</name>
        <name evidence="10" type="ORF">VDA_002522</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 8">
            <text>AMP + ATP = 2 ADP</text>
            <dbReference type="Rhea" id="RHEA:12973"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Purine metabolism; AMP biosynthesis via salvage pathway; AMP from ADP: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6 8">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6 8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="6">Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the adenylate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.3" evidence="6 8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300248.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002522"/>
    <dbReference type="EnsemblBacteria" id="EEZ41490">
        <property type="protein sequence ID" value="EEZ41490"/>
        <property type="gene ID" value="VDA_002522"/>
    </dbReference>
    <dbReference type="GeneID" id="57341248"/>
    <dbReference type="eggNOG" id="COG0563">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1491686at2"/>
    <dbReference type="UniPathway" id="UPA00588">
        <property type="reaction ID" value="UER00649"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004017">
        <property type="term" value="F:adenylate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044209">
        <property type="term" value="P:AMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01428">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00235">
        <property type="entry name" value="Adenylate_kinase_Adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006259">
        <property type="entry name" value="Adenyl_kin_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000850">
        <property type="entry name" value="Adenylat/UMP-CMP_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033690">
        <property type="entry name" value="Adenylat_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007862">
        <property type="entry name" value="Adenylate_kinase_lid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23359">
        <property type="entry name" value="PTHR23359"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05191">
        <property type="entry name" value="ADK_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00094">
        <property type="entry name" value="ADENYLTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01351">
        <property type="entry name" value="adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00113">
        <property type="entry name" value="ADENYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="4 6 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ADK_lid" evidence="9">
        <location>
            <begin position="123"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="NMP" evidence="6">
        <location>
            <begin position="30"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="LID" evidence="6">
        <location>
            <begin position="122"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="10"/>
            <end position="15"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="57"/>
            <end position="59"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="85"/>
            <end position="88"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="132"/>
            <end position="133"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="200"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF05191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ41490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="214" mass="23115" checksum="8D3A883762BAB8B1" modified="2010-01-19" version="1">MRIILLGAPGAGKGTQAQFIMEKFGIPQISTGDMLRAAIKAGTELGKQAKSVIDAGQLVSDDIILGLVKERIAEDDCAKGFLLDGFPRTIPQADGLKEIGVDVDYVIEFDVSDDVIVERMAGRRAHLPSGRTYHVVFNPPKVEGKDDVTGEDLVVRDDDKEETVRARLGVYHEQTAPLIEYYGKEAAAGNTKYLKFDGTLPVAEVSAALEKALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ24</accession>
    <name>D0YZ24_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Heavy metal RND efflux CzcC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002537</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002537"/>
    <dbReference type="EnsemblBacteria" id="EEZ41505">
        <property type="protein sequence ID" value="EEZ41505"/>
        <property type="gene ID" value="VDA_002537"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1538">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1533572at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019889" evidence="2">
        <location>
            <begin position="28"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="425" mass="48005" checksum="72658AB52EFCECFF" modified="2010-01-19" version="1">MFKNTHLSAKSLLGLMVAASFSAPSFANDQLQSLIDWAVEHDSGRQQIHYQAEAMQEMGIAQGQLMDPKLKMGVGGFPVENMGFDNDPMTNISVGLMQQFGRGDTLELLERQAFEQASSIREKAEIRQLDIEKAITTLWVELHYQQQAQKLLKQNQQLFRSLEKYLSTNYGVGVNQAQDIIQSQLQISRIGEKIQANSQMQQKIRAQLGEWLGDQASNLSPKNDPNWAQLSQSLNQSHSNFYPLLAQHPTVKAIEALIKSNETGIDIANEAYKPQFGVEVMYGYRQAKGMNGDPASDLVSAYVTMDLPLFTDKRQDKKLSAAKLQLGATQSQKDLMLKQMNAQAQALFIDRQNITERLGRYNSTLLRQAKEKTRAIERGYQNNTTQLDEYIRAASEELTLQLEQQRLHADLQLANTNLAYLLNKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZA9</accession>
    <name>D0YZA9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002622</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002622"/>
    <dbReference type="EnsemblBacteria" id="EEZ41590">
        <property type="protein sequence ID" value="EEZ41590"/>
        <property type="gene ID" value="VDA_002622"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3018">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="73" mass="8048" checksum="25C66BC4E5E2D82C" modified="2010-01-19" version="1">MRISARAAMEDQQLGLEVADGATDGVIRGAKVIRSYPVGDSYVTEMELDLKLMETMKDHGQIIHVPAQTQTIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZR0</accession>
    <name>D0YZR0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002773</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002773"/>
    <dbReference type="EnsemblBacteria" id="EEZ41741">
        <property type="protein sequence ID" value="EEZ41741"/>
        <property type="gene ID" value="VDA_002773"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="74" mass="8159" checksum="81458A586EEDFCFE" modified="2010-01-19" version="1">MLTLLRQDKLSSFTVSGAQKKASQKLQSCAILWGRSFMIQPYILKLLKDIKHKIGQVFSCSAILALLSSVGSMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZT0</accession>
    <name>D0YZT0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Helicase-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002793</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301023.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002793"/>
    <dbReference type="REBASE" id="38753">
        <property type="entry name" value="Pda61ORFAP"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41761">
        <property type="protein sequence ID" value="EEZ41761"/>
        <property type="gene ID" value="VDA_002793"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1061">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1974">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3886">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="16977at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025202">
        <property type="entry name" value="PLD-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13091">
        <property type="entry name" value="PLDc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="1">
        <location>
            <begin position="227"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="2">
        <location>
            <begin position="429"/>
            <end position="577"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="804" mass="92680" checksum="1203250634671CB2" modified="2010-01-19" version="1">MTNSLYYGHKLSSGSAEDPLLPKLIHAINHASIIEISVSFIMKSGIECLFNPLLDALDSGATIEILTSDYLSVTQPVALRQLMLLVERGARVRVFQCDHNVSFHLKSYICVKTKENCIEQGCAWVGSNNMSRGALCSSYEWALRYDYEHPDDSEAATEFYYIRQQFQRLFKHPATHWLTHSWIDAYIERYQQQSPEIIKLITGSFDISDEPFHPNSIQNEALVALNKTREAGYQRGLVVLATGMGKTWLSAFDAKQLQAQRILFVAHREEILTQAERTFILLNEQASTGHYHGQNKDLDADYLFASIQTLGQEEHLKRFAPDHFDYIVVDEFHHASAPTYQALLNYFTPQFLLGLTATPERSDQANILSLCDNNLVFERNLVHGIDERILVPFDYFGIYDQFVNYQEIPWRNGKFDPKVLDNAFATQLRAQHILKHWQEKKQTRTLAFCISKKHADYMANFFTLAGIKAIAVYSYSEVRRNEALKQLEHGEIDIIFSVDLFNEGTDIPAIDTILMIRPTESKILFLQQLGRGLRQSPTTNKQKLVVLDFIGNHQSFLIKPTALLDVSNIRDLVKKINHGTQLTEGCFINYDLQLVTFWQEMAKRYRINSEEEYQELKTVLGHRPTATEFLQKGYRLDKVRQQYGSWFALVAAQENNEQLKQLVQEFGDFLHRGIAQTAMTKCFKAILLEAFLTLDGFTTAPTTEQLASQSLLVLNRYPELKQRDVAKAEQHCQPNDEKWHKYWLRNPIRAYTTANQDGQRWFSLEDGRFKANFVVNASDREMLHQAVKELVDLRLAEYVLRVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZT8</accession>
    <name>D0YZT8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Soluble lytic murein transglycosylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_002801</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301045.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002801"/>
    <dbReference type="EnsemblBacteria" id="EEZ41769">
        <property type="protein sequence ID" value="EEZ41769"/>
        <property type="gene ID" value="VDA_002801"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0741">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="859969at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1240.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023800">
        <property type="entry name" value="Cucumovirus_coat_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037061">
        <property type="entry name" value="Lytic_TGlycoase_superhlx_L_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012289">
        <property type="entry name" value="Lytic_TGlycosylase_superhlx_L"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008939">
        <property type="entry name" value="Lytic_TGlycosylase_superhlx_U"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008258">
        <property type="entry name" value="Transglycosylase_SLT_dom_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00760">
        <property type="entry name" value="Cucumo_coat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01464">
        <property type="entry name" value="SLT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14718">
        <property type="entry name" value="SLT_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48435">
        <property type="entry name" value="SSF48435"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019267" evidence="2">
        <location>
            <begin position="27"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="domain" description="Cucumo_coat" evidence="3">
        <location>
            <begin position="150"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="SLT_L" evidence="5">
        <location>
            <begin position="405"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="domain" description="SLT" evidence="4">
        <location>
            <begin position="487"/>
            <end position="591"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF14718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="642" mass="72439" checksum="10EE7426CC5569F0" modified="2010-01-19" version="1">MPSISSVKKIFVAVVFALGCSNTATAASLEQQRAWYDQAQKALDNKDISTFKSLRSKLNSYPLTPYLDYREFNAQLSDKTLPQVQSFLKEYSTLPFSTRVKNRYLTNLAADDQWRSYLAVQPTEPSSKWQQCNYVLAQSQTGKATQAWKTTREIWLTGKSLPNSCDDLLEAWAASGNRTNALILQRMQLVLARGDKGLLTHLDKQLSGSAKATGDKMLTLVSSPNKVGAIAKSSAVTATNQEMIASAYQLLARKDPKEAVAQYNQVVSGQKYSAAKKQELADYVASRLMSTQDPQLASWRDSKLKSSDNESVLARRIQSSIREANWSDARSWINRLPTEAKQSTRWTFWHAYVLAKAGKTKEANKIYQSLLGQRDFYSAAAATILKQPITYPKKTAAPNDALLKPYHKTLVRIRELVARDKVVAANSEWAFLLRRVDEPTKKALAVYAEQHKMHHLAVQATISAKMWDHISLRFPVAHKWWYQFFGEKRDIPMTTLMALSRQESAFNTHAQSYVGARGLMQLMPATAKETAQKLGRSYSGVNSLYDPGTNIRLGSGYLKMALDRFDNNRIYAFAGYNAGPGRVNQWRKVTDGKLDAFAFIEQIPFNETRNYVQNILMFDIFYGDQLGQKTSLLRPNELKARY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZX5</accession>
    <name>D0YZX5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ATP-dependent zinc metalloprotease FtsH</fullName>
            <ecNumber evidence="5">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ftsH</name>
        <name evidence="9" type="ORF">VDA_002838</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
            <orientation evidence="5">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">In the C-terminal section; belongs to the peptidase M41 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">In the central section; belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301158.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002838"/>
    <dbReference type="MEROPS" id="M41.001"/>
    <dbReference type="EnsemblBacteria" id="EEZ41806">
        <property type="protein sequence ID" value="EEZ41806"/>
        <property type="gene ID" value="VDA_002838"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0465">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="190468at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01458">
        <property type="entry name" value="FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005936">
        <property type="entry name" value="FtsH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011546">
        <property type="entry name" value="Pept_M41_FtsH_extracell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000642">
        <property type="entry name" value="Peptidase_M41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037219">
        <property type="entry name" value="Peptidase_M41-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06480">
        <property type="entry name" value="FtsH_ext"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01434">
        <property type="entry name" value="Peptidase_M41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140990">
        <property type="entry name" value="SSF140990"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01241">
        <property type="entry name" value="FtsH_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="9" id="KW-0132">Cell division</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 5" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 5" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="AAA" evidence="8">
        <location>
            <begin position="185"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="601"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="601"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="416"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="193"/>
            <end position="200"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="415"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="419"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="493"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="649" mass="71873" checksum="2C98863A3A2582C4" modified="2010-01-19" version="1">MAKNLILWLVIAVVLMSVFQSFGPGDKTSHQIDYTTFVREIGQDQIKEVRFNDREITVYKRDNARYVTYLPVVNDPKLLDDLINANVKVYGTPPEEPSLLASIFISWFPMLLLIGVWIFFMRQMQGGGGKGAMSFGKSKARMMSEDQIKTTFADVAGCDEAKEDVKELVDYLRDPSRFQKLGGKIPTGVLMVGPPGTGKTLLAKAIAGEAKVPFFTISGSDFVEMFVGVGASRVRDMFEQAKKAAPCIIFIDEIDAVGRQRGAGVGGGHDEREQTLNQMLVEMDGFEGNEGIIVIAATNRPDVLDPALLRPGRFDRQVVVGLPDVRGREQILKVHMRKVPLDNDVNPSLIARGTPGFSGADLANLVNEAALFAARGNKRTVSMVEFELAKDKIMMGAERKSMVMSEAQKESTAYHEAGHAIIGRLVPDHDPVYKVSIIPRGRALGVTMYLPEQDRVSHSREYLESMISSLYGGRLAEELIYGVEKVSTGASNDIERATDIARKMVTQWGFSDKLGPLLYAEDEGEVFLGRSVTKSKHMSDDTAKLIDNEVRKLIDRNYARARQILVDNMDIMHAMKDALMKYETIDADQINDLMERKTEIRAPKGWADESDTMKQESVSEETTVAPEAPVNNDDVNDASESDTDTKPQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZZ9</accession>
    <name>D0YZZ9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002862</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301234.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002862"/>
    <dbReference type="EnsemblBacteria" id="EEZ41830">
        <property type="protein sequence ID" value="EEZ41830"/>
        <property type="gene ID" value="VDA_002862"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="750230at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="3"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="292" mass="32186" checksum="1F8EE5E0ADC82ED6" modified="2010-01-19" version="1">MQFSIEQLEAFVAAAETGSFSAGARKLNKAQSVISTAVANLELDLNVTLFDRTTRKPQLTEHGHTLLVKAKRILSQCQQLVANADELQQGVESKLTIALQSMTMSQPLTQALAKFEQDYPFVEIEILNATEDEIVSLLNSGRAQIGALLQLDTLPQEIEAHGIGSLAMVCIVAPSHPLARKSQIDWPDLITHRQIVLSGRHHQHKRWQVSDSIWSTESAISAVNLVMGGIGWTVVPLDMVKDLIAANVLTRLPLSFEGQTWHQGVDIVWTRLHPAGPAARQLRLYLTEARLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z009</accession>
    <name>D0Z009_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ATP-dependent RNA helicase SrmB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_002872</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the DEAD box helicase family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002872"/>
    <dbReference type="EnsemblBacteria" id="EEZ41840">
        <property type="protein sequence ID" value="EEZ41840"/>
        <property type="gene ID" value="VDA_002872"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0513">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4 8" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="6">
        <location>
            <begin position="1"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="7">
        <location>
            <begin position="155"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="319"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="338"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ41840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="374" mass="42488" checksum="7B61F548BDC2FAA5" modified="2010-01-19" version="1">MDFPRRKPGPARVLVLTPTRELAIQVADHARALAKYTDLKIFTITGGISYDEHAELLGKTQDIVVATPGRLMEYIEAERFDCRAIECLILDEADRMLDMGFGKIVERINKECRWRQQSLLFSATLEGKGVREFSQHILNEPLEVNAEPSRRERKKIHQVYHRCDNMEHKLAILEHLLRNDAERTIIFVKTRERLAELRGQLETRQIKCCWIQGEMAQAARSNTIRRFREGVINVMIATDVAARGIDLPDVSHVINFDMPRTADVYLHRIGRTARAGKKGSAISLVEAHDQAMMERVCRYIKEEVPERFVEGLRPATKKAATVKKKKPKNLDKKAKAELAKKKKAKAKKVAKKATKKTAPKTAPKTAPKTAPKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z092</accession>
    <name>D0Z092_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RNA polymerase sigma factor RpoD</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Sigma-70</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rpoD</name>
        <name evidence="10" type="ORF">VDA_002955</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Interacts transiently with the RNA polymerase catalytic core.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the sigma-70 factor family. RpoD/SigA subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301416.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002955"/>
    <dbReference type="EnsemblBacteria" id="EEZ41923">
        <property type="protein sequence ID" value="EEZ41923"/>
        <property type="gene ID" value="VDA_002955"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0568">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1565734at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00963">
        <property type="entry name" value="Sigma70_RpoD_SigA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000943">
        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009042">
        <property type="entry name" value="RNA_pol_sigma70_r1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007624">
        <property type="entry name" value="RNA_pol_sigma70_r3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007631">
        <property type="entry name" value="RNA_pol_sigma_70_non-ess"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007127">
        <property type="entry name" value="RNA_pol_sigma_70_r1_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042189">
        <property type="entry name" value="RNA_pol_sigma_70_r1_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012760">
        <property type="entry name" value="RNA_pol_sigma_RpoD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028630">
        <property type="entry name" value="Sigma70_RpoD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04546">
        <property type="entry name" value="Sigma70_ner"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03979">
        <property type="entry name" value="Sigma70_r1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00140">
        <property type="entry name" value="Sigma70_r1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04539">
        <property type="entry name" value="Sigma70_r3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00046">
        <property type="entry name" value="SIGMA70FCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02393">
        <property type="entry name" value="RpoD_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00715">
        <property type="entry name" value="SIGMA70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00716">
        <property type="entry name" value="SIGMA70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RNA_pol_sigma70" evidence="8">
        <location>
            <begin position="409"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_sigma70" evidence="9">
        <location>
            <begin position="578"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="6">
        <location>
            <begin position="579"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="167"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Sigma-70 factor domain-2" evidence="6">
        <location>
            <begin position="385"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Sigma-70 factor domain-3" evidence="6">
        <location>
            <begin position="464"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Sigma-70 factor domain-4" evidence="6">
        <location>
            <begin position="553"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Interaction with polymerase core subunit RpoC" evidence="6">
        <location>
            <begin position="409"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="187"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ41923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="619" mass="70819" checksum="D7F41B8E05C988E7" modified="2010-01-19" version="1">MEQNPQSQLKLLVAKGKEQGYLTYAEVNDHLPEDIVDSDQVEDIIQMINDMGIKVVETAPDADELMMTEDNADEDAIEAAAQALSSVESEIGRTTDPVRMYMREMGTVELLTREGEIDIAKRIEDGINQVQCSVAEYPKAISQLLDMFDKVEADELRLTDIISGFVDPNEEETAAPTATHIGSELSESDLEDEDRDLDEDEDEDEDGDSSDDSDDNNIDPEVAREKFTELRQSYEKMALAIDTHGRNHPTAELAVDELSEIFKQFRLVPKQFDKLIGSLRDSMDRVRTNERLIMRMCVDNSKMPKKTFINLFAGNEASSEWIDEALNSGKPYAERLKTYEEELRRCSTKLRLLEEETGLSIERIKDISRRMSIGEAKARRAKKEMVEANLRLVISIAKKYTNRGLQFLDLIQEGNIGLMKAVDKFEYRRGYKFSTYATWWIRQAITRSIADQARTIRIPVHMIETINKLNRISRQMLQEMGREPLPEELAERMQMPEDKIRKVLKIAKEPISMETPIGDDEDSHLGDFIEDTTLQLPMDAATQTNLRAATNEVLAGLTPREAKVLRMRFGIDMNTDHTLEEVGKQFDVTRERIRQIEAKALRKLRHPSRSDVLRSFLDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0D6</accession>
    <name>D0Z0D6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">3'(2'),5'-bisphosphate nucleotidase CysQ</fullName>
            <ecNumber evidence="7">3.1.3.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">3'-phosphoadenosine 5'-phosphate phosphatase</fullName>
            <shortName evidence="7">PAP phosphatase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">cysQ</name>
        <name evidence="8" type="ORF">VDA_002999</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Converts adenosine-3',5'-bisphosphate (PAP) to AMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>adenosine 3',5'-bisphosphate + H2O = AMP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10040"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58343"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="3.1.3.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell inner membrane</location>
            <topology evidence="7">Peripheral membrane protein</topology>
            <orientation evidence="7">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the inositol monophosphatase superfamily. CysQ family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.7" evidence="7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301513.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002999"/>
    <dbReference type="EnsemblBacteria" id="EEZ41967">
        <property type="protein sequence ID" value="EEZ41967"/>
        <property type="gene ID" value="VDA_002999"/>
    </dbReference>
    <dbReference type="GeneID" id="57340551"/>
    <dbReference type="eggNOG" id="COG1218">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1741160at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008441">
        <property type="term" value="F:3'(2'),5'-bisphosphate nucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046855">
        <property type="term" value="P:inositol phosphate dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006790">
        <property type="term" value="P:sulfur compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02095">
        <property type="entry name" value="CysQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006240">
        <property type="entry name" value="CysQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020583">
        <property type="entry name" value="Inositol_monoP_metal-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020550">
        <property type="entry name" value="Inositol_monophosphatase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00377">
        <property type="entry name" value="IMPHPHTASES"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01331">
        <property type="entry name" value="bisphos_cysQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00629">
        <property type="entry name" value="IMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00630">
        <property type="entry name" value="IMP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="2 7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="87"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="65"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="85"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ41967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="246" mass="27070" checksum="7BDB1D8861D3897A" modified="2010-01-19" version="1">MAISLDTLLAIATDAGNIILQHYHGQLSVETKADNSPVTSADLAANEIIVSRLRQLTPNIPILSEELIHQDWSVRQQWQQFWLVDPLDGTKEFIRKNGEFTVNIALVEQGKPILSVVHAPALQKSWIADGSQAWLITSATKEVLKVRPATVPTVVGSRSHPSSELQAYLTQLGEHKFIEVGSSLKFCLIAEGRAHVYPRLGPTMMWDTAAGQCVLTSAGGSVQLLDGQTLSYHRPELLNPYFIARN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0J9</accession>
    <name>D0Z0J9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Anaerobic C4-dicarboxylate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_003063</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 8">Cell inner membrane</location>
            <topology evidence="3 8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 8">Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301730.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003063"/>
    <dbReference type="EnsemblBacteria" id="EEZ42030">
        <property type="protein sequence ID" value="EEZ42030"/>
        <property type="gene ID" value="VDA_003063"/>
    </dbReference>
    <dbReference type="GeneID" id="57340466"/>
    <dbReference type="eggNOG" id="COG2704">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="591678at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015556">
        <property type="term" value="F:C4-dicarboxylate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004668">
        <property type="entry name" value="Anaer_Dcu_memb_transpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36106">
        <property type="entry name" value="PTHR36106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03605">
        <property type="entry name" value="DcuA_DcuB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004539">
        <property type="entry name" value="C4-dicrbxl_trns"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00770">
        <property type="entry name" value="Dcu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="90"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="133"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="165"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="228"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="263"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="295"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="323"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="359"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="412"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR004539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ42030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="435" mass="45462" checksum="6C64FBB7273211DF" modified="2010-01-19" version="1">MIGVELFVVLAFIFLGARIGGIGIGFAGGAGVIVLSLILGVPTSQSFIPVDVILIIMSVITAIAAMQVAGGMDWLVQLAEDFLRKNPKRITFYAPIVTYLMTLMAGTGHTAFSTLPVIAEVAKGQGIRPSRPLSIAVVASQIAITASPISAAVVFFSGILEPLGVSYITLLAICIPTTFAACMVGAFVANFMGCDLKDDPVYQERLAKGLISLENKTRREIKPEAKRATYIFIAAIVFVVCYAAAISHSIGLIENPTLGRNEAIMTVMLTAAAAIVLTTKIDASLIAQAPTFRSGMTACICVLGVAWLGSTFVNAHVDGIKEVAGALLSDYPWMLALVLFFASMLLYSQGATTTALMPAALAIGVSPVTAIASFAAVSALFVLPTYPTLLAAVEMDDTGSTRIGNLVFNHPFFVPGVVTITTSVALGFVVGGMLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0R4</accession>
    <name>D0Z0R4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Galactoside O-acetyltransferase</fullName>
            <ecNumber evidence="3">2.3.1.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_003128</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.3.1.18" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301948.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003128"/>
    <dbReference type="EnsemblBacteria" id="EEZ42095">
        <property type="protein sequence ID" value="EEZ42095"/>
        <property type="gene ID" value="VDA_003128"/>
    </dbReference>
    <dbReference type="GeneID" id="57340644"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="834114at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008870">
        <property type="term" value="F:galactoside O-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004343">
        <property type="term" value="F:glucosamine 6-phosphate N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006048">
        <property type="term" value="P:UDP-N-acetylglucosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039143">
        <property type="entry name" value="GNPNAT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012660">
        <property type="entry name" value="YiiD_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13355">
        <property type="entry name" value="PTHR13355"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13673">
        <property type="entry name" value="Acetyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09500">
        <property type="entry name" value="YiiD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02447">
        <property type="entry name" value="yiiD_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="201"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ42095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="305" mass="34970" checksum="AF8CAA584CACDDC3" modified="2010-01-19" version="1">MFRLVTPQSEQELKLYFHFRWQMLREPWQLPIGSERDAYDDLSCHRMILTDAGEVIAIGRLYMTADNDGQIRYMAVHPDFRHRGMGAVILMALEGLARQEGAKRLVCNAREDAIPFYVRNGFVSQGELSDERGPVRHQQMLKQLEALSDVVRHPDWCQELQQLWLNQIPISDKMGIRIHQYTGYRFEVGALFHANLNPNEFMFAGSIFTMATLAGWGFLWMLLKEHKFAANIVLVDSHIRYHNPIAERPRAITSVEQVEGNFDRLARGRKTKITVEVSVYGGDTLASTFTGTYLLLPVQDDAVVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0S7</accession>
    <name>D0Z0S7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Coproporphyrinogen-III oxidase</fullName>
            <ecNumber evidence="8">1.3.98.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">VDA_003141</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in the heme biosynthesis. Catalyzes the anaerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen III to yield the vinyl groups in protoporphyrinogen IX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>coproporphyrinogen III + 2 S-adenosyl-L-methionine = 2 5'-deoxyadenosine + 2 CO2 + 2 L-methionine + protoporphyrinogen IX</text>
            <dbReference type="Rhea" id="RHEA:15425"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:57307"/>
            <dbReference type="ChEBI" id="CHEBI:57309"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="EC" id="1.3.98.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8 10">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="8 10">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 8">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; protoporphyrinogen-IX from coproporphyrinogen-III (AdoMet route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 8">Belongs to the anaerobic coproporphyrinogen-III oxidase family.</text>
    </comment>
    <dbReference type="EC" id="1.3.98.3" evidence="8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301982.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003141"/>
    <dbReference type="EnsemblBacteria" id="EEZ42108">
        <property type="protein sequence ID" value="EEZ42108"/>
        <property type="gene ID" value="VDA_003141"/>
    </dbReference>
    <dbReference type="GeneID" id="57340631"/>
    <dbReference type="eggNOG" id="COG0635">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1130951at2"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00323"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051989">
        <property type="term" value="F:coproporphyrinogen dehydrogenase activity"/>
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        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004109">
        <property type="term" value="F:coproporphyrinogen oxidase activity"/>
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        <property type="project" value="InterPro"/>
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        <property type="term" value="F:metal ion binding"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Coprogen_oxidase_HemN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034505">
        <property type="entry name" value="Coproporphyrinogen-III_oxidase"/>
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    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
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        <property type="entry name" value="HemN_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13932">
        <property type="entry name" value="PTHR13932"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06969">
        <property type="entry name" value="HemN_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000167">
        <property type="entry name" value="HemN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00277">
        <property type="entry name" value="oxygen-independent_coproporphy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00538">
        <property type="entry name" value="hemN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 10" id="KW-0408">Iron</keyword>
    <keyword evidence="8 10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6 8" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="11">
        <location>
            <begin position="47"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="68"/>
            <end position="70"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <label>2</label>
        </ligand>
    </feature>
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        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <label>1</label>
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        <location>
            <begin position="113"/>
            <end position="114"/>
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        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
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        <location>
            <position position="145"/>
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        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <label>1</label>
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        <location>
            <position position="172"/>
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        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
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        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
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        </ligand>
    </feature>
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        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <label>2</label>
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        <location>
            <position position="243"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <label>2</label>
        </ligand>
    </feature>
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        <location>
            <position position="329"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <label>1</label>
        </ligand>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00001496"/>
        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00004496"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00004785"/>
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            <dbReference type="ARBA" id="ARBA00005493"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00024295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR000167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000167-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000167-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ42108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="457" mass="53257" checksum="BAE45E174CED3D48" modified="2010-01-19" version="1">MPNTQIIWDQALIEKYNYSGPRYTSYPTALEFHQEFSEAEFETACHQYPERKLSLYVHIPFCHKLCYYCGCNKVITRHQEKADVYLDALALEIAQRAALCGPRQVSQLHWGGGTPTFLTKEQITRLMNLLREHFDFDADAEISIEIDPRRIELDMLDHLRQEGFNRISIGVQDFNKEVQKVINREQDEKFIFDLVQRAKELGFRSTNLDLIYGLPLQNQQAFSDTLHEVLKMKPGRLSVFNYAHMPQLFAAQRKIKDEWLPGPKEKLAMLQQSIATLTGAGYQFIGMDHFALPDDELAVAQRNGILHRNFQGYTTQGDCDLLGLGVSAISMIGDCYAQNQKELKAYYADIEQQQHALWKGVQLDQDDLIRREVIKALICNFQLKKHDIEAMFDLKFDQYFAEDLQLLQTFINDDLVRVDDEMIYVEPKGRLLIRNICMCFDKYLRERARQQQFSRVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0T5</accession>
    <name>D0Z0T5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA helicase</fullName>
            <ecNumber evidence="3">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">VDA_003149</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the helicase family. RecQ subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302007.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003149"/>
    <dbReference type="EnsemblBacteria" id="EEZ42116">
        <property type="protein sequence ID" value="EEZ42116"/>
        <property type="gene ID" value="VDA_003149"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0514">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="54580at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004589">
        <property type="entry name" value="DNA_helicase_ATP-dep_RecQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006293">
        <property type="entry name" value="DNA_helicase_ATP-dep_RecQ_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010997">
        <property type="entry name" value="HRDC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002121">
        <property type="entry name" value="HRDC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044876">
        <property type="entry name" value="HRDC_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032284">
        <property type="entry name" value="RecQ_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018982">
        <property type="entry name" value="RQC_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00570">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16124">
        <property type="entry name" value="RecQ_Zn_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09382">
        <property type="entry name" value="RQC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00341">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00956">
        <property type="entry name" value="RQC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47819">
        <property type="entry name" value="SSF47819"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01389">
        <property type="entry name" value="recQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00614">
        <property type="entry name" value="recQ_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50967">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 12" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="36"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="225"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="domain" description="HRDC" evidence="9">
        <location>
            <begin position="532"/>
            <end position="612"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ42116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="613" mass="69484" checksum="BA042F9B1D2A2975" modified="2010-01-19" version="1">MTQTSFCDHPTLAQAQTLLEDVFGYQQFRDGQQDIITTALNRSDSLVIMPTGGGKSLCYQIPALLLDGLTLVISPLISLMKDQVDQLVANGIQAACIHSALTRDEIETVFSQLESGELKLLYVSPERVLMRDFIARLQQVKLALLAVDEAHCISQWGHDFRPEYAELGQLKQMFAPLPVMALTATADETTRQDIISRLALEQPHIHLGSFDRPNIRYTLLEKYKPLSQLLSYLASVRGQCGIIYCNSRKRVEQICEKLCENGLRAAAYHAGMSVNDRAYVQEAFQRDDIHIVVATVAFGMGINKPNVRFVIHHDIPRNIESYYQETGRAGRDGLPAEAVLLYDPADMAWLRRCLDEKPDGATREVEEHKLNAMRDFAEAQTCRRQVLLHYFGQHSEKPCGNCDICLDPPKQFNATEVAQKALSCVYRVQQSFGVNHIIEVLRGMQNHRIRDHGHELLSTYGIGRDFSHEYWLSVLRQLIHRGLLVQNIQRNSTLQLTEQSRSVLRGEVELMLAVPRLDTAARTAKHDKLAQRHYDKKLFAKLRKLRKAIADDENLPPYVVFNDVSLMEMAERLPTSHGEFLAINGVGQRKLEKYGQVFLELIEDHLTAVEGLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0Y8</accession>
    <name>D0Z0Y8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">LysM domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003202</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302148.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003202"/>
    <dbReference type="EnsemblBacteria" id="EEZ42169">
        <property type="protein sequence ID" value="EEZ42169"/>
        <property type="gene ID" value="VDA_003202"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1652">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1833920at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="SSF54106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LysM" evidence="1">
        <location>
            <begin position="31"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="352" mass="39935" checksum="E3A3526493E228E1" modified="2010-01-19" version="1">MKRWLGLVGLALWVPLVWADYLPIVRQDAPQTYIVKKGDTLWDISSYFLDNPWLWPKLWHANSYIKNPHLIYPGDRLRLRWVKGQPQLVLDRGKAQVKLTPKMRIASSPITTLHDSLMFPYLAEDKLLSAQSLENVARVIGSSDGRSYMAPGDTIWVDSVLDGGSEWWIYRINETFSREGEGTKHQVMALQEVAKARVKAIDKERSLLRLTQLRQEIHQNDLVLPAPIDTRSLNMSFAPTVAPSQLQAQVVGSISGQQYMASKQVVILDRGHLDNFEPGQVFKLYRDGADISGPRGEYAYHDSRFSGAEQQLKHIEVGEVMVLRPYEYFSLAVVTKSFEPFKAGVVALPPTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z107</accession>
    <name>D0Z107_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Acetolactate synthase</fullName>
            <ecNumber evidence="4 8">2.2.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">VDA_003221</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>H(+) + 2 pyruvate = (2S)-2-acetolactate + CO2</text>
            <dbReference type="Rhea" id="RHEA:25249"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:58476"/>
            <dbReference type="EC" id="2.2.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="8">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
        <text evidence="8">Binds 1 thiamine pyrophosphate per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 1/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 1/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the TPP enzyme family.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.6" evidence="4 8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302200.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003221"/>
    <dbReference type="EnsemblBacteria" id="EEZ42188">
        <property type="protein sequence ID" value="EEZ42188"/>
        <property type="gene ID" value="VDA_003221"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="391134at2"/>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00055"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00059"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003984">
        <property type="term" value="F:acetolactate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd02015">
        <property type="entry name" value="TPP_AHAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012846">
        <property type="entry name" value="Acetolactate_synth_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039368">
        <property type="entry name" value="AHAS_TPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012000">
        <property type="entry name" value="Thiamin_PyroP_enz_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012001">
        <property type="entry name" value="Thiamin_PyroP_enz_TPP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000399">
        <property type="entry name" value="TPP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045229">
        <property type="entry name" value="TPP_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme-bd_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18968">
        <property type="entry name" value="PTHR18968"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00205">
        <property type="entry name" value="TPP_enzyme_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02776">
        <property type="entry name" value="TPP_enzyme_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00118">
        <property type="entry name" value="acolac_lg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00187">
        <property type="entry name" value="TPP_ENZYMES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="6 8 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TPP_enzyme_N" evidence="11">
        <location>
            <begin position="1"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_M" evidence="9">
        <location>
            <begin position="189"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_C" evidence="10">
        <location>
            <begin position="375"/>
            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ42188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="548" mass="59371" checksum="6CE2FC8D0DFEA5A1" modified="2010-01-19" version="1">MTGAELVVKALQQQGITTVFGYPGGAIMPIYDALYDGGVEHILCRHEQGAAMAAIGMARSTQHVAVCMATSGPGATNLVTGLADAFLDSVPLVAITGQVASSHIGTDAFQEMDVIGMSLACCKHSYLVTDIDELASTLAEAFVVATSGRPGPVLVDIAKDVQLAEVPDPTTYHFQPPAPPIATNEQIMAAQQLLSQAQRPVLYVGGGVQIAHATQVVRQFHQHNPMPAVSTLKGLGTIERHHPYYLGMLGMHGTRAANLVVQECDLLLVIGARFDDRVTGKLDTFAPHAKVIHLDIDAAEINKLRQANVALRGEIQAVLPQLELGSDISEWLEHCQQLRTKFKWRYDHPGERIYAPALLKNLSDKMAENTVIATDVGQHQMWAAQHIQPRSPENFLSSAGLGTMGFGLPAAIGAQIARPHDDVVLITGDGSFMMNVQELGTIKRKQLPVKIILLNNQRLGMVRQWQSLFFDGRYSETILDDNPDFVALAKAFAIDGQTISRKEDIEGALETLLQSKGPYLLEVVISEQDNVWPLVPPGAANQDMLENT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z165</accession>
    <name>D0Z165_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DNA recombination protein RmuC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_003279</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in DNA recombination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RmuC family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302370.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003279"/>
    <dbReference type="EnsemblBacteria" id="EEZ42246">
        <property type="protein sequence ID" value="EEZ42246"/>
        <property type="gene ID" value="VDA_003279"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1322">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1309809at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003798">
        <property type="entry name" value="DNA_recombination_RmuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30563">
        <property type="entry name" value="PTHR30563"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02646">
        <property type="entry name" value="RmuC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="42"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ42246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="508" mass="57993" checksum="BECD0B761BACF0FF" modified="2010-01-19" version="1">MTEWLSGGGLATLAALSGATIASIITAMWLRGRYEQELALVEQQADNELKLSQAREAQLQQQLQQSNEELDEMDVERDRLTAELRQMHGRLAAAVEKMRYFEALKTEKQYVTEQLENARAANANLEADLREQYARHFEEQKAAEEKIKLLENAEERLRIQFESLANRLFEQKSRSVDEQNRISLEGLLMPLKEQLEGFKKQVNDSFSYEARERHTLIHQINSLKQLNEQMAKEAVNLTQALKGDNKAQGNWGEVILARVLSESGLREGHEYQTQVSLENDEGKRYQPDVVVRLPENKDVVIDAKMSLVAYERFYHAELAAERELALSEHVASVRGHMRGLSRKDYHQLHGVRSLDYVLMFIPVEPAFQAAIEADPALIRDAMDLNIMLVSPTTLLVALRTINNLWRNERQNQNAKEIAERASRLYDKLRLFVTDMEAMGASLEKANQSYQGAMNKLVSGRGNVLRQAESFKQLGVEVKRDINPQLTERAMFEGGFAEQVDALTHQDDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1E7</accession>
    <name>D0Z1E7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">O-antigen ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_003361</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302570.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003361"/>
    <dbReference type="EnsemblBacteria" id="EEZ42328">
        <property type="protein sequence ID" value="EEZ42328"/>
        <property type="gene ID" value="VDA_003361"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3307">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007016">
        <property type="entry name" value="O-antigen_ligase-related"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04932">
        <property type="entry name" value="Wzy_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="5"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="60"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="84"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="140"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="165"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="188"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="212"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="316"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="347"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ42328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="395" mass="44894" checksum="3AEF7DC4D726BDAF" modified="2010-01-19" version="1">MKDRVFSFFILLPFIWLSTGMLILKNGDKTMVAMIIISIIATVCRYGLTSIKQNLSNKMLWLVIAIAAYTLFSYAYHGLSSRELRAIIGSLLFLLFLPTQLITQNRLIGLVVLGSIVSSLYAWYYGIYLGLGRSWPMNPIPYSTLIVSFAIMSLSFALASTDKRVKVITTVCFSFSCLALIIGESRGLWLALALTLFTFAIYSMIRFYQPKYWLYIMGLVILIGSMGIVLKPQLEARWQQTEQEYQAIQNGNMCTSIGLRLQMWQAASILVEDDPILGTGDAHIQKLDELYHQGRIEKCLYQYQPAHYHNQYLDRFVKNGVIGLILLLALLLCPITQIKKLNNTKQYILLGIITVYISASLTDVPLNHGQTLFMYFFYIFGACCYSQDAQRELNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1I4</accession>
    <name>D0Z1I4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 9">Argininosuccinate synthase</fullName>
            <ecNumber evidence="2 9">6.3.4.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">Citrulline--aspartate ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">argG</name>
        <name evidence="10" type="ORF">VDA_003398</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10932"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57472"/>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.4.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 9">Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the argininosuccinate synthase family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.5" evidence="2 9"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003398"/>
    <dbReference type="EnsemblBacteria" id="EEZ42365">
        <property type="protein sequence ID" value="EEZ42365"/>
        <property type="gene ID" value="VDA_003398"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0137">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00113"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004055">
        <property type="term" value="F:argininosuccinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01999">
        <property type="entry name" value="Argininosuccinate_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00005">
        <property type="entry name" value="Arg_succ_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001518">
        <property type="entry name" value="Arginosuc_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018223">
        <property type="entry name" value="Arginosuc_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023434">
        <property type="entry name" value="Arginosuc_synth_type_1_subfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024074">
        <property type="entry name" value="AS_cat/multimer_dom_body"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11587">
        <property type="entry name" value="PTHR11587"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00764">
        <property type="entry name" value="Arginosuc_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69864">
        <property type="entry name" value="SSF69864"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00032">
        <property type="entry name" value="argG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00564">
        <property type="entry name" value="ARGININOSUCCIN_SYN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00565">
        <property type="entry name" value="ARGININOSUCCIN_SYN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3 9" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="11"/>
            <end position="19"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>L-citrulline</name>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>L-citrulline</name>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="126"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>L-citrulline</name>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>L-citrulline</name>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>L-citrulline</name>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="264"/>
        </location>
        <ligand>
            <name>L-citrulline</name>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="276"/>
        </location>
        <ligand>
            <name>L-citrulline</name>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ42365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="404" mass="44449" checksum="8B0C390381632A8B" modified="2010-01-19" version="1">MMSQINKVVLAYSGGLDTSAIIPWLKENYDCEVVAFVADVGQGEAELDGIEAKAIASGASSCYIADLKEEFVKDYIYPSLKTGATYEGKYLLGTSMARPIIAKAQVECALAIGADALCHGCTGKGNDQVRFESTYAALAPQLSVIAPWREWDLRSREALLDYLAERGIPCSASLEKIYSRDANAWHISTEGGVLEETWNQPNEHCWVWTNDPEQAPEQAEFVALTVEHGEVVAVDGEPMTPYNALVYLNEKGALHGVGRIDIVENRLVGMKSRGCYETPGGTIMMEALRGVEQLVLDKESFEFRQTVGLKASHLIYDGRWFTPLCQSLFAAANELAKDVSGEVVIKLYKGQATVVQKRSNNSLYSEQFATFGEDEVYDHSHAGGFIRLYSLASRIRAMNNQNKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1J1</accession>
    <name>D0Z1J1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type IV pilus biogenesis protein PilN</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003405</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302655.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003405"/>
    <dbReference type="EnsemblBacteria" id="EEZ42372">
        <property type="protein sequence ID" value="EEZ42372"/>
        <property type="gene ID" value="VDA_003405"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3166">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1673053at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007813">
        <property type="entry name" value="PilN"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05137">
        <property type="entry name" value="PilN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="213" mass="24093" checksum="B328D5FC969A7752" modified="2010-01-19" version="1">MIQKLNLLPWREQKRKQHQQRFYAILLGSVLLSLGGVFTAGSYLEQQQQIQQQRNAIISQEIQKLEQRLALLPKLDKQRAELNKRLAVITEIQTERNRVTNLFSVLPELVPHGVYLNDLSLKAGNVSVTGHGDSNGRLANLLSNAEQSLWLKDVSMHSILATKGVNAEDITKFSASFFMLKPHERALKIAQQIEANKKAVTAPQHQELKEVTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1L7</accession>
    <name>D0Z1L7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003431</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302698.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003431"/>
    <dbReference type="EnsemblBacteria" id="EEZ42398">
        <property type="protein sequence ID" value="EEZ42398"/>
        <property type="gene ID" value="VDA_003431"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2319">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002372">
        <property type="entry name" value="PQQ_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13360">
        <property type="entry name" value="PQQ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="157"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="325" mass="35410" checksum="F9EA7224558F1158" modified="2010-01-19" version="1">MRQVTVLLFLIVACFSLTGCLFNEKAVQGWDIDPQGATTLSLNPQGQIALVASSTQGLSLWDLHQSKKLATLGWQDPDHNLILHSAFSNNSRFAITATAQTFTVWDLGWGRALGLWSIDDAIIEDVAIANNGEKIALALSNNKVLYLNLGTGRRLEFLGHREKVNSVDMSANGKYVLSGGSDNNAFLWSTQTGQVIYPFPMKSRITQVALQQDGRFALVGDSTKHIAIWDLKTGQQQSKLNVKLRQQIISSARFSLSGDHVITGTPAGRVELWSALTGKNIKRWQMSGRKNTRPAATLVYDVAISPNTTAIAGTSAGLINAWSTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1M4</accession>
    <name>D0Z1M4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">30S ribosomal protein S10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpsJ</name>
        <name evidence="6" type="ORF">VDA_003438</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in the binding of tRNA to the ribosomes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS10 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302781.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003438"/>
    <dbReference type="EnsemblBacteria" id="EEZ42405">
        <property type="protein sequence ID" value="EEZ42405"/>
        <property type="gene ID" value="VDA_003438"/>
    </dbReference>
    <dbReference type="GeneID" id="57340105"/>
    <dbReference type="eggNOG" id="COG0051">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2012682at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.600">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00508">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001848">
        <property type="entry name" value="Ribosomal_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018268">
        <property type="entry name" value="Ribosomal_S10_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027486">
        <property type="entry name" value="Ribosomal_S10_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036838">
        <property type="entry name" value="Ribosomal_S10_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11700">
        <property type="entry name" value="PTHR11700"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00338">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00971">
        <property type="entry name" value="RIBOSOMALS10"/>
    </dbReference>
    <dbReference type="SMART" id="SM01403">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54999">
        <property type="entry name" value="SSF54999"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01049">
        <property type="entry name" value="rpsJ_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00361">
        <property type="entry name" value="RIBOSOMAL_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal_S10" evidence="5">
        <location>
            <begin position="7"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ42405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="103" mass="11725" checksum="1DBA799F90D985BC" modified="2010-01-19" version="1">MQNQRIRIRLKAFDHRLIDQSTAEIVETAKRTGAQVKGPIPLPTRKERFTVLISPHVNKTARDQYEIRTHKRLIDIVEPTDKTVDALMRLDLAAGVDVQISLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1Q1</accession>
    <name>D0Z1Q1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">50S ribosomal protein L17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rplQ</name>
        <name evidence="6" type="ORF">VDA_003465</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Part of the 50S ribosomal subunit. Contacts protein L32.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the bacterial ribosomal protein bL17 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303526.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003465"/>
    <dbReference type="EnsemblBacteria" id="EEZ42432">
        <property type="protein sequence ID" value="EEZ42432"/>
        <property type="gene ID" value="VDA_003465"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1838961at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1030.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01368">
        <property type="entry name" value="Ribosomal_L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000456">
        <property type="entry name" value="Ribosomal_L17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036373">
        <property type="entry name" value="Ribosomal_L17_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14413">
        <property type="entry name" value="PTHR14413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01196">
        <property type="entry name" value="Ribosomal_L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64263">
        <property type="entry name" value="SSF64263"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00059">
        <property type="entry name" value="L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01167">
        <property type="entry name" value="RIBOSOMAL_L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ42432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="128" mass="14566" checksum="E30CCF1E853829DA" modified="2010-01-19" version="1">MRHRKSGRQLNRNSSHRKAMFSNMASSLVRHELIKTTLPKAKELRRVIEPLITLAKTDSVANRRLAFARTRDNEVVAKLFNELGPRFAQRPGGYTRIIKCGFRAGDKAPMAYIELVDRSEAKEEATAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1R5</accession>
    <name>D0Z1R5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Na(+)/H(+) antiporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_003479</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303562.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003479"/>
    <dbReference type="EnsemblBacteria" id="EEZ42446">
        <property type="protein sequence ID" value="EEZ42446"/>
        <property type="gene ID" value="VDA_003479"/>
    </dbReference>
    <dbReference type="GeneID" id="57340048"/>
    <dbReference type="eggNOG" id="COG0025">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1194802at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015299">
        <property type="term" value="F:solute:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018422">
        <property type="entry name" value="Cation/H_exchanger_CPA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10110">
        <property type="entry name" value="PTHR10110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0050">Antiport</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0915">Sodium</keyword>
    <keyword evidence="7" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="71"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="100"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="128"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="203"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="295"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="318"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="356"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="391"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="domain" description="Na_H_Exchanger" evidence="9">
        <location>
            <begin position="11"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ42446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="426" mass="46538" checksum="439A69EFBDE60733" modified="2010-01-19" version="1">MSVYSTLCYLAAAAMLIAFVNSKIGKMQTTIAITAGSLILSLGIIIAGHNGWFHLEDIAATQLSEINFEDFLLKGILGFLLFAGGLGIKLPHLEDQKWEITLLALGATLFSTFFIGASLWGICQLLGIGLDLIYCLLFGALISPTDPIAVLAIVKKLNAPRRISTQIEGESLFNDGFGLVIFVTLFTIAFGSETPTVLGVGHLFVQEALGGIAYGFALGLIFHYLISSTNDHSMELLLTLGIPTTGYVFAQYLHVSGPLAMVVSGIMIGNWTRYIGFSKESEEHLDHFWELVDEFLNGVLFLLIGMTMLQFSFHQEDWVLMAIAVPLVLLARFLSVRLSYVAFNRYRTYNPFSVKILTWGGLRGGLALAMAMAIPAGTLVIPEKNIDVREIILVMTYAVVVFSILIQGSTITPLIQKAKAWEAAQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1S1</accession>
    <name>D0Z1S1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3 4">Single-stranded DNA-binding protein</fullName>
            <shortName evidence="2">SSB</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_003485</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303576.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003485"/>
    <dbReference type="EnsemblBacteria" id="EEZ42452">
        <property type="protein sequence ID" value="EEZ42452"/>
        <property type="gene ID" value="VDA_003485"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1942216at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04496">
        <property type="entry name" value="SSB_OBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00984">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000424">
        <property type="entry name" value="Primosome_PriB/ssb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011344">
        <property type="entry name" value="ssDNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10302">
        <property type="entry name" value="PTHR10302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00436">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002070">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00621">
        <property type="entry name" value="ssb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50935">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="2" id="KW-0234">DNA repair</keyword>
    <keyword evidence="2" id="KW-0235">DNA replication</keyword>
    <keyword evidence="1 2 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="DNA-binding region" evidence="2">
        <location>
            <begin position="55"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="114"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Important for interaction with partner proteins" evidence="2">
        <location>
            <begin position="177"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="114"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR002070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ42452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="182" mass="20131" checksum="D8A48434B6ECB5D7" modified="2010-01-19" version="1">MASRGVNKVILVGNLGNDPEVRYMPNGGAVANITIATSETWRDKATGENREKTEWHRVVLFGKLAEVAGEYLRKGSQVYIEGQLQTRKWQNQQGQDQYTTEIVVQGFNGVMQMLGGRQNQGGQGMGAPMGGQQQQGSWGQPQQPAAQNFAPQQQQQQAPAQQPAPQQQYNEPPMDFDDDIPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1T1</accession>
    <name>D0Z1T1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MSHA biogenesis protein MshM</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003495</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303605.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003495"/>
    <dbReference type="EnsemblBacteria" id="EEZ42462">
        <property type="protein sequence ID" value="EEZ42462"/>
        <property type="gene ID" value="VDA_003495"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="947558at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13401">
        <property type="entry name" value="AAA_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="42"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="282" mass="31785" checksum="499A26606D83DE04" modified="2010-01-19" version="1">MYQAYFGFHQAPFALTPNTELFHALPPHVEAIQTTLAALTMGEGIIHISGEVGTGKTLVCRMLIQRLPAHCDLAYIPTPPKEGDELKIALAIELGLEPPKDRIALTSQLQHELIRRKELGRSVVVILDEAQALSDDCLETIRLLGNLETEFEKLLQIVLLSQPELDQRLQQHHLRQLQQRITFRAQLRALDLAETVAYIEHRLYQAGCRLPLFSLPQSKLIWQASNGIPRLINQLCHKALIAASSSQLQMVGQREILMAIQDTPGARQPRWLFPVPWGWSKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1U8</accession>
    <name>D0Z1U8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">PmbA protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_003512</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase U62 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303654.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003512"/>
    <dbReference type="EnsemblBacteria" id="EEZ42479">
        <property type="protein sequence ID" value="EEZ42479"/>
        <property type="gene ID" value="VDA_003512"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0312">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="958356at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045569">
        <property type="entry name" value="Metalloprtase-TldD/E_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045570">
        <property type="entry name" value="Metalloprtase-TldD/E_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002510">
        <property type="entry name" value="Metalloprtase-TldD/E_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035068">
        <property type="entry name" value="TldD/PmbA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036059">
        <property type="entry name" value="TldD/PmbA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01523">
        <property type="entry name" value="PmbA_TldD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19289">
        <property type="entry name" value="PmbA_TldD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19290">
        <property type="entry name" value="PmbA_TldD_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111283">
        <property type="entry name" value="SSF111283"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PmbA_TldD" evidence="2">
        <location>
            <begin position="32"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="PmbA_TldD_M" evidence="4">
        <location>
            <begin position="124"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="PmbA_TldD_C" evidence="3">
        <location>
            <begin position="240"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF19289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF19290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ42479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="447" mass="48268" checksum="EBA35892AACA3872" modified="2010-01-19" version="1">MDVREQVAQQRVELEAAVAKALEMAGQKADAAEVAINKTTGISVSTRLSEVENVEFNSDGALGITVYRGQRKGSASTSDLSENAIAQTVAAALDIASYTSEDPFAGPGPKELMAKDIPDLDLFHPDEPEPDRAAEIAIAAEEAAMAYDPRIKQSDGASYDSHYGIRVYGNSHGMLASYASSRHSISCCVIAQGKNGEMERDYSYTTARRACDMWTPEKVGRHAAERTVGRVDAQKLSTREAPVMFAADIATGLFGHLVMGISGANLYRKSSFLLDKLGEEIFPNWLNISERPHILRGMASTPFDSEGLATKDLEIIKDGQLATYLLTSYAARKMNRQPTGHAGGIHNWLVSSTGENFTQMLKKMDRGLLVTELMGQGVNIVTGDYSRGAAGFWVENGEIQFPVSEITIAGNLADMMKNIVAVGSDIETRSQIQTGSILLDSMKIAGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1V2</accession>
    <name>D0Z1V2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 10">RNA polymerase sigma-54 factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">VDA_003516</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the sigma-54 factor family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303666.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003516"/>
    <dbReference type="EnsemblBacteria" id="EEZ42483">
        <property type="protein sequence ID" value="EEZ42483"/>
        <property type="gene ID" value="VDA_003516"/>
    </dbReference>
    <dbReference type="GeneID" id="57340009"/>
    <dbReference type="eggNOG" id="COG1508">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1906842at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001216">
        <property type="term" value="F:DNA-binding transcription activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000394">
        <property type="entry name" value="RNA_pol_sigma_54"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007046">
        <property type="entry name" value="RNA_pol_sigma_54_core-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007634">
        <property type="entry name" value="RNA_pol_sigma_54_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038709">
        <property type="entry name" value="RpoN_core-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32248">
        <property type="entry name" value="PTHR32248"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00309">
        <property type="entry name" value="Sigma54_AID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04963">
        <property type="entry name" value="Sigma54_CBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04552">
        <property type="entry name" value="Sigma54_DBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000774">
        <property type="entry name" value="RpoN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00045">
        <property type="entry name" value="SIGMA54FCT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02395">
        <property type="entry name" value="rpoN_sigma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00717">
        <property type="entry name" value="SIGMA54_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00718">
        <property type="entry name" value="SIGMA54_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 10" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5 10" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="9 10" id="KW-0804">Transcription</keyword>
    <keyword evidence="6 10" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Sigma54_CBD" evidence="13">
        <location>
            <begin position="126"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma54_DBD" evidence="12">
        <location>
            <begin position="327"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="54"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="54"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR000774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF04552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF04963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEZ42483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="487" mass="54874" checksum="136236A77AF55DD0" modified="2010-01-19" version="1">MKTSLQLKLGQQLAMTPQLQQAIRLLQLSTLDLQQEIQEALDANPLLELEENLADNEENKPSDSDYSDSHDEIKDSESFDTSEVIEQQEMPQDLPVDTTWDDVYSAGTGSTGIALDDDMPIYQGETTESLQDYLMWQVQLTPFSDTDLAIATAIIDAVDDQGYLSCSSQDILESLGDDEVELDEVEAVLKRIQQFDPLGVASRNLQECLLLQLATYAPETLWLNEAKMLLSQHIDLLGNRDFRQLMRETKLKEAELKEVMQLIHGLDPRPGNRVVATETEYVVPDVSVYKDNGKWVVTINPDSVPRIKVNEQYAALSKQTRNSADSQFIKTHLQDAKWLIKSLESRNETLLKVARCIVEHQQDFFEYGEEAMKPMVLNDIALAVDMHESTISRVTTQKYMHTPRGIFELKYFFSSHVSTDSGGECSSTAIRALVKKLVAAENQSKPLSDSKIATLLAEQGIMVARRTIAKYRESLGIPPSNQRKRLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1V8</accession>
    <name>D0Z1V8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">YrbG protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_003522</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303686.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003522"/>
    <dbReference type="EnsemblBacteria" id="EEZ42489">
        <property type="protein sequence ID" value="EEZ42489"/>
        <property type="gene ID" value="VDA_003522"/>
    </dbReference>
    <dbReference type="GeneID" id="57340003"/>
    <dbReference type="eggNOG" id="COG0530">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="804531at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004481">
        <property type="entry name" value="K/Na/Ca-exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004837">
        <property type="entry name" value="NaCa_Exmemb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044880">
        <property type="entry name" value="NCX_ion-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10846">
        <property type="entry name" value="PTHR10846"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01699">
        <property type="entry name" value="Na_Ca_ex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00367">
        <property type="entry name" value="TIGR00367"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="129"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="168"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="208"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="239"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="273"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="303"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="Na_Ca_ex" evidence="6">
        <location>
            <begin position="5"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="Na_Ca_ex" evidence="6">
        <location>
            <begin position="174"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ42489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="321" mass="33770" checksum="77A8149EC5C5E21C" modified="2010-01-19" version="1">MLEAVVLLCVGLALLVWSADRLVFGSAALARNMGVAPLVIGMTILAMGSSAPEMMVSATAALAGKTDTAVGNVLGSNIANIALILGVTAMLKPLAIGSTIIRRELPLMLVVTLIAGALLWDNYLGFAEGVLLLVLFVLFLLAMLYISKKAKQEGDVMVDEQESEIPQNVSNTASFIWIIVGLALLLYSSDMVVESAVTIAKYYGMSDLVIGLTIIAVGTSLPELAASVASVLKGEDDMAVGNIIGSNVFNILAVMGIPGILNPSAISPLAMGRDFYVMLGVSVLLLIMALGKNRRINRVEGGILLICFIAYQAYLFYNLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1X0</accession>
    <name>D0Z1X0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 18">Ubiquinol-cytochrome c reductase iron-sulfur subunit</fullName>
            <ecNumber evidence="5 18">7.1.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">VDA_003534</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17 18">
            <text>a quinol + 2 Fe(III)-[cytochrome c](out) = a quinone + 2 Fe(II)-[cytochrome c](out) + 2 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:11484"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="7.1.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="18">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="18">Binds 1 [2Fe-2S] cluster per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 19">The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="18">The Rieske protein is a high potential 2Fe-2S protein.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Rieske iron-sulfur protein family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.8" evidence="5 18"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303722.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003534"/>
    <dbReference type="EnsemblBacteria" id="EEZ42501">
        <property type="protein sequence ID" value="EEZ42501"/>
        <property type="gene ID" value="VDA_003534"/>
    </dbReference>
    <dbReference type="GeneID" id="57339989"/>
    <dbReference type="eggNOG" id="COG0723">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1632945at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008121">
        <property type="term" value="F:ubiquinol-cytochrome-c reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014349">
        <property type="entry name" value="Rieske_Fe-S_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005805">
        <property type="entry name" value="Rieske_Fe-S_prot_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019470">
        <property type="entry name" value="Ubiq_cytC_Rdtase_Fe-S_su_TAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006317">
        <property type="entry name" value="Ubiquinol_cyt_c_Rdtase_Fe-S-su"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10134">
        <property type="entry name" value="PTHR10134"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10399">
        <property type="entry name" value="UCR_Fe-S_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00162">
        <property type="entry name" value="RIESKE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="SSF50022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01416">
        <property type="entry name" value="Rieske_proteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="16" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="18" id="KW-0249">Electron transport</keyword>
    <keyword evidence="13" id="KW-0408">Iron</keyword>
    <keyword evidence="14" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="15" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="21" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="18" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Rieske" evidence="20">
        <location>
            <begin position="91"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00019816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00029351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU004494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="RuleBase" id="RU004497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="EEZ42501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="197" mass="21137" checksum="627A9ACAD44E861D" modified="2010-01-19" version="1">MSNTPISSGRRRFLTVTTSVVGGLGAAAIAVPFIKSWNPSAKAKAAGAPVEVDISKLEEGQMIRVEWRGKPVWVVRRSDAVLKQLEGHDEQLRDAASDEPQQPDYAKNAYRSVKPEIFLAVGICTHLGCSPTYLPNTFSEQVSGIASGFFCPCHGSKFDMAGRVFSGVPAPLNLVVPPHTFLDDNTILVGVDGEEVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z216</accession>
    <name>D0Z216_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF2062 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001865</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298837.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40833">
        <property type="protein sequence ID" value="EEZ40833"/>
        <property type="gene ID" value="VDA_001865"/>
    </dbReference>
    <dbReference type="GeneID" id="57342011"/>
    <dbReference type="eggNOG" id="COG3216">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1672574at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018639">
        <property type="entry name" value="DUF2062"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09835">
        <property type="entry name" value="DUF2062"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2062" evidence="2">
        <location>
            <begin position="22"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="182" mass="20813" checksum="65E6436F88C65923" modified="2010-01-19" version="1">MPRQIIKRYLPNHETIKRQKALRIFGNVLYNPNLWCLNRRSASGAFAVGLFMAFVPLPSQMIMAAGLAILFGVNLPLSVALVWVSNPITMPVLFYGAYKIGAWVMNTPHLPFHFELSWEFLLHQMSQIGPPFLLGCFICSVTCALLGYFGIRGLWRYSVVRSWNKRKFRLSTLTKKSTYIPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2D3</accession>
    <name>D0Z2D3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000584</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304774.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000584"/>
    <dbReference type="EnsemblBacteria" id="EEZ39564">
        <property type="protein sequence ID" value="EEZ39564"/>
        <property type="gene ID" value="VDA_000584"/>
    </dbReference>
    <dbReference type="OrthoDB" id="331838at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="252" mass="27927" checksum="07D864CABA6926AF" modified="2010-01-19" version="1">MVGLAIAIAIAIAIAIAIAIAIAIAIAIAGGLGCLWFKDSPIEAWLANGPFGKDKEARFRDEYAVLEDPKQALMTWLNFIIGIKVTVYPMNKVAGQLHLSADVLQRVKAKPKTHCIHIATNLPMALNEKNITIEAVQAIKETQLTLKTAHTSTKLMKLYALSPEGITSVGNSFIYFVNAPKLPEKKPITDMRTQTFYEEVVLVKARVTYQDTVFPLPSLDKDKMVINQYAPSKVNFTQHQDEWADNFESTVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2E5</accession>
    <name>D0Z2E5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_000596</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304816.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000596"/>
    <dbReference type="EnsemblBacteria" id="EEZ39576">
        <property type="protein sequence ID" value="EEZ39576"/>
        <property type="gene ID" value="VDA_000596"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0834">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="847343at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015276">
        <property type="term" value="F:ligand-gated ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001320">
        <property type="entry name" value="Iontro_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00062">
        <property type="entry name" value="PBPb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00079">
        <property type="entry name" value="PBPe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="183"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="211"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="PBPb" evidence="4">
        <location>
            <begin position="33"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="PBPe" evidence="5">
        <location>
            <begin position="33"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ39576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="364" mass="41297" checksum="79D9B864C095D7D9" modified="2010-01-19" version="1">MATVQHHKRILYLVILAVFVLIIFPTKTYSQDKLVIATYHCPPFVIHQPDGSYEGLSILLWQRIAETLNIEYQFEQHSLKELLTAVETGKANVGVSCISITPERERVIDFSHSFYETHLAIAVKKQGYWQSIVSIFTNTRLLMVLGFVFACACFVGGIYYLLEHKVNDKLYSMKSTRSQLVEGFILGLLFITKGPFNYYEFKTLTGRVITVLLAVATTLFIASITAVLTSTFTLGLINSDIKSPNDLANVSTGAKQASTSSLFLTNHSIVHTTYPTVEDYLTALDHKEVDAVVGDDAILKYQIKIAKERGQFESLIVLPYQFEKQNYGFALEENSPYEEEINRALLEFRQSNEWRQALLKYFAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-02-10" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2L4</accession>
    <name>D0Z2L4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Divalent cation tolerance protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000665</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CutA family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000665"/>
    <dbReference type="EnsemblBacteria" id="EEZ39645">
        <property type="protein sequence ID" value="EEZ39645"/>
        <property type="gene ID" value="VDA_000665"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1324">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010038">
        <property type="term" value="P:response to metal ion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004323">
        <property type="entry name" value="Ion_tolerance_CutA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03091">
        <property type="entry name" value="CutA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="SSF54913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="51" mass="5784" checksum="7B9F7BC020A2F112" modified="2010-01-19" version="1">MIKTKTALFDQVEAEIKAIHDYETPEVIALPITAGSQDYLDWISTECKKID</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2N1</accession>
    <name>D0Z2N1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000682</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305047.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000682"/>
    <dbReference type="EnsemblBacteria" id="EEZ39662">
        <property type="protein sequence ID" value="EEZ39662"/>
        <property type="gene ID" value="VDA_000682"/>
    </dbReference>
    <dbReference type="GeneID" id="57343026"/>
    <dbReference type="eggNOG" id="COG4221">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="313524at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025638">
        <property type="entry name" value="DUF4336"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33835">
        <property type="entry name" value="PTHR33835"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14234">
        <property type="entry name" value="DUF4336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="236" mass="27299" checksum="2F4E79B0A73DFA61" modified="2010-01-19" version="1">MIEWMKDRIWYQDGQFSQLGIAVGSRMTIIKLADEKLFIHSPIQLTTQLQLELSKLGHVAMVVTPNLNHHLFLSEWWLAYPSAYFYAPPGLQQKRSDLVFDGTLNTKTEPLWHGQLLQTVLKGSDTMEEVIFCDPLSRTLIIGDSLVWLKNRTSPISILLGLINGCYFNPAMPYYWRLSFHNKTRMRQSLQEILTWPFDRIILSHGQVIETDGKALFAKAFHWVLNDTLPLSNHEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2R0</accession>
    <name>D0Z2R0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chaperone protein DnaJ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000711</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000711"/>
    <dbReference type="EnsemblBacteria" id="EEZ39691">
        <property type="protein sequence ID" value="EEZ39691"/>
        <property type="gene ID" value="VDA_000711"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0484">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="SSF46565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="SSF49493"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="296" mass="32413" checksum="AAD33DBBB794C6EF" modified="2010-01-19" version="1">MLGLTKNASEKEIKKAYKKLAMKYHPDKNPDDPSAADKFKEVKEAYEILTDKEKRAAYDQFGHQAFERGGMGGNGYEGHQQYGNYADFEDIFGGAFGDMFSKARGGHFGGGGFGGFGNRPRKGNDLHYKMEVDFEDAIKGTSRVIDIPTYEGNVQSTKKLNIKIPMGIKDGEQIRLGGKGEPGINGGPAGDILIEITVRPHLRFTRHGNNLHTKVKTDFVTATLGGKVEVQTLDSRFNLTIPAGTQAGRKFKLTGKGVTDRKGHTGDLIAELVIETPTNLTERQKELLTEFAAASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2R9</accession>
    <name>D0Z2R9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Putative PTS system EIIc component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_000720</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305152.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000720"/>
    <dbReference type="EnsemblBacteria" id="EEZ39700">
        <property type="protein sequence ID" value="EEZ39700"/>
        <property type="gene ID" value="VDA_000720"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3641">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="814081at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008982">
        <property type="term" value="F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003352">
        <property type="entry name" value="PTS_EIIC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13303">
        <property type="entry name" value="PTS_EIIC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="33"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="93"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="133"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="174"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="259"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="310"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="domain" description="PTS_EIIC" evidence="9">
        <location>
            <begin position="32"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ39700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="351" mass="36705" checksum="A18C0F83B72D230A" modified="2010-01-19" version="1">MQSINTHPPHHRISSFLKQKNISLSAKVYLVDVMSYMALGLFSSLLIGSIFNSIGVKFDIPLFTDTLWPLAKQMTGPAIGVAVAYALQAPPLVLFSSVISGAAGAMLGGPVGAYVAALIAAESGKLVAGSTKVDILITPAVTIITGILVGNFIGPHVNWLMSSLGDLIMAATQLQPIVMGALVAVLMGMALTLPISSAAIAIMLSLNGISAGAATVGCATQMVGFAVMSFRENGWGGLVAQGLGTSMLQMPNIIRNYKIWLPTIITSAILGPIATTVFELQNTPLGAGMGTSGFVGQIQTVIAMDNTPAFTLYSLILLMHFILPATITLFFAEVMRNKGWIKPGDLTLTLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2T0</accession>
    <name>D0Z2T0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative amino acid ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_000731</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial solute-binding protein 3 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000731"/>
    <dbReference type="EnsemblBacteria" id="EEZ39711">
        <property type="protein sequence ID" value="EEZ39711"/>
        <property type="gene ID" value="VDA_000731"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0834">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015276">
        <property type="term" value="F:ligand-gated ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001320">
        <property type="entry name" value="Iontro_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018313">
        <property type="entry name" value="SBP_3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00062">
        <property type="entry name" value="PBPb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00079">
        <property type="entry name" value="PBPe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01039">
        <property type="entry name" value="SBP_BACTERIAL_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PBPb" evidence="5">
        <location>
            <begin position="1"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="PBPe" evidence="6">
        <location>
            <begin position="2"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="221" mass="24901" checksum="054C53A79024FCA5" modified="2010-01-19" version="1">MRDKQGELIGFEVDVARRVAQDAGLKIEFIPTAWDGIIPALLAGKFDVIIGGLSITPQRNLNVLFTVPYAHSGVQLAASKKSAADKTTIADYNKRSVTLAVRRGAVTVQTAKKYFPKAKLRQFDDESQAFQEVLNGNADAVLASSPKPEQMAIQYKDKLFIPFKENLNRGSEGFALRQGEFDLLNFFNNWIMLRTEDGWLQSRHDYWFKTLDWENQVAEGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2U5</accession>
    <name>D0Z2U5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000746</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305235.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39726">
        <property type="protein sequence ID" value="EEZ39726"/>
        <property type="gene ID" value="VDA_000746"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0697">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1179190at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="184"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="219"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="247"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="273"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="13"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="159"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="304" mass="33980" checksum="053B5EC4304BBB17" modified="2010-01-19" version="1">MERNDSLTRIFYIVLMGFGFPIMRYMSIHFDTLNNNAIRFLSGGIFFCVICLFKFREEIKTILKDYRTVLSLFLLATFMTANMFFFINGLKYTSAISGSIFGILAMPLGIIFASIFYSDEQKIVTNRRFTYGAIIAFLGSLIFVLNSNYSNGNEIIYTGYIYLTCAITIQSIQNLIVKKLALNLPAIVISASTATLSGIIFLSITIYTDTFSNLKEVPFTLITGLIFAGIYGMLMAFYILKKQGVAIFNMTQLLIPISTGIIGYMTLGETISIMQMIGGIIVIFGCILASKQEHSKRETNTLST</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z341</accession>
    <name>D0Z341_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">McrBC 5-methylcytosine restriction system component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000842</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000842"/>
    <dbReference type="EnsemblBacteria" id="EEZ39822">
        <property type="protein sequence ID" value="EEZ39822"/>
        <property type="gene ID" value="VDA_000842"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4268">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019292">
        <property type="entry name" value="McrC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38733">
        <property type="entry name" value="PTHR38733"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10117">
        <property type="entry name" value="McrBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="425" mass="48798" checksum="E10477082AC130B2" modified="2010-01-19" version="1">MIVVREFGLLLNGGNESSTDCHSIPSKAFEWLMVNGQSNNQDSVDLIKVKKHGRSIALQVINYVGVLETPCGIRIEIHPKISDKQDTQATMKVLLKMLSTVYKLNMHRFEHSSLQTLNRPLFEVLISYFLKEVSNIIQQGIRSRYTRVQDCKPYLKGQLQTSKQINQRPGCLNSFHISYDEFSPDRAENRLIRSALNQVIKWSKNSDNLRLGSELQCALDDIPCSKNYALDFRQWSKDRSLVHYRSVKPWCKLILNYQSPVSLSGRHKGISMLFPMESLFEQYVAIRLGKSLSHALTLRTQVSNCALVTHTPRSGKSQEWFRLKPDIVVWDKTLHKPLCVADTKWKRINEKQATAKHKYGISQSDMYQMFAYGQNCLGGSGVVYLIYPAYEDFNESLPPFKFDNRLSVKAIPYDLTNDECELLSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z349</accession>
    <name>D0Z349_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Hypothetical beta-ketoacyl synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_000850</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305524.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000850"/>
    <dbReference type="EnsemblBacteria" id="EEZ39830">
        <property type="protein sequence ID" value="EEZ39830"/>
        <property type="gene ID" value="VDA_000850"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="181584at2"/>
    <dbReference type="UniPathway" id="UPA00848">
        <property type="reaction ID" value="UER00151"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000794">
        <property type="entry name" value="Beta-ketoacyl_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11712">
        <property type="entry name" value="PTHR11712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PKS_KS" evidence="4">
        <location>
            <begin position="144"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="618" mass="66102" checksum="D7D278C5B31122B1" modified="2010-01-19" version="1">MAKLPLIVGFGGINAAGRSSGFHSYKRMLADVLPQETMASTWQDLAIRMGLSDTGCDVSDEIIAAIKAGTLVRRIDSFDPDALLYQYKANLETESEAITFTLRKSKLPTQIPDNWLVEEQGSKVKITVTGSIDALLEDRVTFPVSSGGNIPAGFDPGKLYNSRFHPRGLKLTVYGASDALNSLGFEWNQVLEHVKPDEISVYAGSGLAQVDDQSLAGMIAAHLTGGRVSSKMMALSLAEMPADFINGYVINSVGTTGTNMGACATFLYNLRQGMYDIQHGKSKVVIVGNAEAPVAPEVMEGFRVMGALAEDEQLKALDNSDCVDNSRACRPFSTNAGFTMAEASQFVVLMDDELALELGANIYGSVADVFVNADANKKSISAPGVGNYVTVAKAAALAKAILGAEGVKQTYVQSHGTGTPQNRVTESHILNEVAKTFAIDKWPVAAIKSYVGHSMSAAAGDQLIASLGVWQYGWIPGITTIDHIADDVHQSNLEILTSHKFAGEQGEAYKAVVLNAKGFGGNNATGLVLSPQQTLEMLTVKYGQECIDSYKTRNTPVAQIAKQNDLAACQGQETIRYDFGSEVMDGDSVEMDQQSLKLSAFAQAIDLPTVNPFAEYSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z362</accession>
    <name>D0Z362_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ATP-dependent RNA helicase DeaD</fullName>
            <ecNumber evidence="6">3.6.4.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Cold-shock DEAD box protein A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">deaD</name>
        <name evidence="6" type="synonym">csdA</name>
        <name evidence="13" type="ORF">VDA_000863</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000863"/>
    <dbReference type="EnsemblBacteria" id="EEZ39843">
        <property type="protein sequence ID" value="EEZ39843"/>
        <property type="gene ID" value="VDA_000863"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0513">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070417">
        <property type="term" value="P:cellular response to cold"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00964">
        <property type="entry name" value="DEAD_helicase_DeaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005580">
        <property type="entry name" value="DbpA/CsdA_RNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028618">
        <property type="entry name" value="DEAD_helicase_DeaD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03880">
        <property type="entry name" value="DbpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6 8" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 6 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="Q_MOTIF" evidence="12">
        <location>
            <begin position="6"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="37"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="231"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="447"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="565"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="7">
        <location>
            <begin position="6"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ39843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="647" mass="72829" checksum="BCD6E3E74C83D3EF" modified="2010-01-19" version="1">MQESVTEFRQLELADTLLSALDKMGFVAPTPIQAASIPLLLTGTDALGKAQTGTGKTAAFSLPLLNKLKLSQHKPQAIVMAPTRELAIQVAAEVKTLGQNIQGLKVLEIYGGASIVDQMRALKNGAHIVVGTPGRVKDLITRDRLHLDEVHTFVLDEADEMLKMGFVDDVTWIMEQAPETAQRVLFSATMPPIVKEIVDRFLRNPARIDVAGENRTVAKVDQQFWVVKGVEKDEAMMRLLETEDTDASIVFVRTRQDTERLADWLCARGFKAAALHGDIPQSLRERTVEHIKRGVIDILVATDVVARGLDVPRITHVFNYDIPFDVESYIHRIGRTGRAGREGKAILLVRTNQIRMLRTIERVTKSRMEEIQLPLRDAVAEARLNRLAKELEAQKEQSSVEAFVELVEKLQESIEVDAATLAAMLLQRQQGNRPLFYKGPDPMIAALERDKQRRDRRGNDRDRGERGERGERRERRTFNAADWDTYQLQVGREQGIQVKDVVGAIANELGLNKDFIGAIKLAPEHTYVQLPKKMTAEVAAQLKKLRIRQNEVKAVVVDGEVLREHRRGGRDGNRDGNRGGYRGNRDGNRDGNREGGRGRRDGERRFDRNRGGDNRGTYRGERNHGGDRNNSNGGERRRSDRKPRFES</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3R8</accession>
    <name>D0Z3R8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative altronate dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001069</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001069"/>
    <dbReference type="EnsemblBacteria" id="EEZ40049">
        <property type="protein sequence ID" value="EEZ40049"/>
        <property type="gene ID" value="VDA_001069"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2721">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="85" mass="9435" checksum="9A4D5B2554813F44" modified="2010-01-19" version="1">MEIISADNEVIAEIKALQKIPFGNKIALCDIAHAEHINKCGHSIGKSIIEIPLGQLVHVQNVRSERLDIPESIIEEIIKQMGIEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3S9</accession>
    <name>D0Z3S9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">PTS system N-acetylgalactosamine-specific IIB component</fullName>
            <ecNumber evidence="9">2.7.1.69</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_001080</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.7.1.69" evidence="9"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306171.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001080"/>
    <dbReference type="EnsemblBacteria" id="EEZ40060">
        <property type="protein sequence ID" value="EEZ40060"/>
        <property type="gene ID" value="VDA_001080"/>
    </dbReference>
    <dbReference type="GeneID" id="57343451"/>
    <dbReference type="eggNOG" id="COG3444">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1696140at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103111">
        <property type="term" value="F:D-glucosamine PTS permease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008982">
        <property type="term" value="F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00001">
        <property type="entry name" value="PTS_IIB_man"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.35.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004720">
        <property type="entry name" value="PTS_IIB_sorbose-sp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036667">
        <property type="entry name" value="PTS_IIB_sorbose-sp_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018455">
        <property type="entry name" value="PTS_IIB_sorbose-sp_subgr"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03830">
        <property type="entry name" value="PTSIIB_sorb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52728">
        <property type="entry name" value="SSF52728"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00854">
        <property type="entry name" value="pts-sorbose"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51101">
        <property type="entry name" value="PTS_EIIB_TYPE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0598">Phosphotransferase system</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="5 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PTS EIIB type-4" evidence="8">
        <location>
            <begin position="2"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ40060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="166" mass="18172" checksum="A31B4EC69E8A5F4E" modified="2010-01-19" version="1">MTAPNIVWTRIDERLLHGQIRITWGKHSEANLILVANDDAADGPNAAFMQAGMKASAGGEYAVRFFSIQKTIDVIHKASPQQKIFILCNNPTDVARLVEGGVPITHCNVGNMHFHEGKRQIAKTVSVDEKDIDAFERMVARGVTCTVQNTPDQNPVPVLELAKTVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z404</accession>
    <name>D0Z404_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001157</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306371.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40135">
        <property type="protein sequence ID" value="EEZ40135"/>
        <property type="gene ID" value="VDA_001157"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502ZBCH">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="801597at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="614" mass="70212" checksum="5D09B27FC3838810" modified="2010-01-19" version="1">MHLELHIKSGSRSGEVIRLNEVGSQLEPSSWVKENEVIELLLRVPAKFQSAILNLYDHRVAATYVDCDENYTNFIWKPQRQKNRLLECLFINYFGLAELSVELEDEEESKVIKNFAPLEIFASKLNAQNVEDMLSYLATLGDEQLHSLFQTTKHGAGFKEGSTSPNGSLERLEHTIDKLSFLFQSLFSKPITKLLPEHRVLQASGEEDLDDSALGWLLDNLSVVEEVDDIDRAHFEFNNRMYKAHSVQVPILKESSNLYENQVIHGFIVTLLNEADKQLTNYNRTGSLKSAFCEDMPDGYSSFFTQVNRFKKELLGNQIKRCVRAIERVEFLKHSLDKSIPVTNYILERPILTQKAEAHLSYRGVFIEYINWFERSCPDWSVYQNLLAIKSIPTLFESYAYYRISESLNNILNPIKKGHKPIGALIHDIDGNEISLVREPTYWMPKNSHSNESSYINSEGKVLNKGKVKPRSSQHKYSHRCPDVVIEVRKENKPSKLIVLDAKYTYPTLAFSKYLPECTMKYVHGIHNRSNNKSLVCSMTIVHPIGDADESLQSFHTFDYSIEGRMPVSPSLQALGLQLGLSQDSDRLNETLKFLLKQAGVAIPENLQLPLFIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z418</accession>
    <name>D0Z418_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Hydrogenase 4 Fe-S subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001171</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001171"/>
    <dbReference type="EnsemblBacteria" id="EEZ40149">
        <property type="protein sequence ID" value="EEZ40149"/>
        <property type="gene ID" value="VDA_001171"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1142">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13247">
        <property type="entry name" value="Fer4_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12837">
        <property type="entry name" value="Fer4_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="16"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="87"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="216" mass="23016" checksum="A80A5D51A2614181" modified="2010-01-19" version="1">MLLYWGFLRLTGRAMKSFVIADPEKCIGCGTCMAACSTVHKQEGLQSHPRLTVVKQNDATAPVMCRHCEDAPCAAVCPVQAITKQDDRVLLNETLCVGCTLCAVACPFGAIAFDGSRPIAMANSYDIYIPSTPRSSNPSTSIPSTFGQDILAWEPGVKSIAVKCDLCGFRDEGPACAQVCPTQAIMVVDEEKIAKARQIKRAQAAESSAVVQGGEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4G0</accession>
    <name>D0Z4G0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH lacI-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000416</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39398">
        <property type="protein sequence ID" value="EEZ39398"/>
        <property type="gene ID" value="VDA_000416"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="37" mass="3847" checksum="31F67C5038DF79F3" modified="2010-01-19" version="1">MKKLGYRPNAAARTLVSQSTNTMGVVVGMSPIPSLVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4G3</accession>
    <name>D0Z4G3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glutathione synthase</fullName>
            <ecNumber evidence="4">6.3.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">VDA_000419</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Sulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the eukaryotic GSH synthase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.3" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304316.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000419"/>
    <dbReference type="EnsemblBacteria" id="EEZ39401">
        <property type="protein sequence ID" value="EEZ39401"/>
        <property type="gene ID" value="VDA_000419"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502Z9VE">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="285125at2"/>
    <dbReference type="UniPathway" id="UPA00142">
        <property type="reaction ID" value="UER00210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004363">
        <property type="term" value="F:glutathione synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1080.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005615">
        <property type="entry name" value="Glutathione_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014042">
        <property type="entry name" value="Glutathione_synthase_a-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014709">
        <property type="entry name" value="Glutathione_synthase_C_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014049">
        <property type="entry name" value="Glutathione_synthase_N_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037013">
        <property type="entry name" value="GSH-S_sub-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004887">
        <property type="entry name" value="GSH_synth_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11130">
        <property type="entry name" value="PTHR11130"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03917">
        <property type="entry name" value="GSH_synth_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03199">
        <property type="entry name" value="GSH_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001558">
        <property type="entry name" value="GSHase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0317">Glutathione biosynthesis</keyword>
    <keyword evidence="5 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GSH_synthase" evidence="11">
        <location>
            <begin position="200"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ39401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="480" mass="53459" checksum="750AB9508ED8ABD1" modified="2010-01-19" version="1">MHNDKFTVKAVNDAVEWAMTHAMMLKDSPFSASHAAFVATPTQISAQRYQTLIDTAPLLGKMVDAVSEDALFIQQAIKPLVSGDTFFSALLTMHQKIHFSESPVRRVPMLIMRSDFMDDAVLGPKLIEFNAIAAGMWPFGQRAHELHHYLQNQWPTTFTPWQGEGAATLIENKAIEQLGEGIAKATFQIKQEFNDSTPATFLMVVQANEDNVFDQHLLELELQRRGIRTIRRTFSELYGNLSTGDNHRLLLEGIGSIDTVYLRAGYQFSDYCSDNIVEEVCCEALMNTRMFMEQHRIAMNATVGQQLASSKRVQMLLSSMPVSELSSFGLTITEAEQVKSVLGEMLPVTDQSVSWFATQSEQDWVLKNQGEGGGHCIFGQDIAPKLSVLRTEDFHAWSLMRRLQLQPRTTPALAVRKGQTEIIDDLISEIGIFTVHLAGKPITQNKGYAGYLIRSKSTRTTEGGIHSGQGVLDSLALSEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4L3</accession>
    <name>D0Z4L3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytosine/purines uracil thiamine allantoin permease family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_000471</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the purine-cytosine permease (2.A.39) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304455.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000471"/>
    <dbReference type="EnsemblBacteria" id="EEZ39451">
        <property type="protein sequence ID" value="EEZ39451"/>
        <property type="gene ID" value="VDA_000471"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="326558at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001248">
        <property type="entry name" value="Pur-cyt_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026030">
        <property type="entry name" value="Pur-cyt_permease_Fcy2/21/22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31806">
        <property type="entry name" value="PTHR31806"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02133">
        <property type="entry name" value="Transp_cyt_pur"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002744">
        <property type="entry name" value="Pur-cyt_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="38"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="68"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="109"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="178"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="211"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="254"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="296"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="337"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="362"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="407"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="432"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR002744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ39451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="465" mass="49514" checksum="1EF820997C309E55" modified="2010-01-19" version="1">MTMHNSTDNQFDVDSSIDELGIGLIPPSHQTKKPSELFFVWCAANIGILGVVYGAIIVSFGLSFFQSVLAAIVGVASFSLVGISSIAGKIGRTTTLTLSRSSFGKKGNIAPTAFCWLNLMGWEAVNIITGTLTLVALFVAVGFEENTFLTTFSLILFGGLTVAVSILGQDTVLTMQKWITRTFGAMTFVVAVYLMFTANWHTILALPSGDWLTGFLPAVSIIAAGTGISWAIAGADYSRDQSPHSSQGSIFQSVVGGAALPLIMLMLTGILLTSQIPDLASNENPISAIGKLLPNWMAIPYLAAAVAGIITIAVLSLYSASLNLLSMGVKLKQRTAITLDAIIVLTIAVYVLFISGDFLGPFISFLVFCGIFLASWAAIFVTDFYHNHVKQGYTEQELYGDTGINKPTLACWLIGSLSGLMVSKTGFIDGPFAIGVFADSSLGLFISFAVAMILYRIVLISKKAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4P2</accession>
    <name>D0Z4P2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Inorganic pyrophosphatase/exopolyphosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304544.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000500"/>
    <dbReference type="EnsemblBacteria" id="EEZ39480">
        <property type="protein sequence ID" value="EEZ39480"/>
        <property type="gene ID" value="VDA_000500"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2253">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="798280at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014942">
        <property type="entry name" value="AbiEii"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08843">
        <property type="entry name" value="AbiEii"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="313" mass="36269" checksum="709DA32C4EFC1114" modified="2010-01-19" version="1">MNKLKHQFLEVSDALALGNPAIIEKDYWVVALLAQLEKLTIDSHQLVFSGGTALAKSNVKIMRMSEDVDIKLIPNADFYTLSRSKKKTVRKLLLEILEKVIEESNTFSIEDKQAWDEYRYVEYDLKYPQQFSQAPCLRPIIKLELMETIPLQETEQRSIQSLVAELYRTKKEVKAFTCVSVHVTLVEKIISMLRRTMLAKRDENRKDDHTLVRHIYDVYCIDATQPIDIESLSPLFNAVLQEDITRFGNQHDEFVNNPSKELQSGLSELEANSLYRQRFEAFVTPMVFNQQPHDFDTCFASFKRIAASLIKKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4Q9</accession>
    <name>D0Z4Q9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Inosine-uridine preferring nucleoside hydrolase</fullName>
            <ecNumber evidence="4">3.2.2.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000517</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.2.2.1" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304596.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000517"/>
    <dbReference type="EnsemblBacteria" id="EEZ39497">
        <property type="protein sequence ID" value="EEZ39497"/>
        <property type="gene ID" value="VDA_000517"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1957">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1763387at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008477">
        <property type="term" value="F:purine nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045437">
        <property type="term" value="F:uridine nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901564">
        <property type="term" value="P:organonitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.245.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015910">
        <property type="entry name" value="I/U_nuclsd_hydro_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001910">
        <property type="entry name" value="Inosine/uridine_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023186">
        <property type="entry name" value="IUNH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036452">
        <property type="entry name" value="Ribo_hydro-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12304">
        <property type="entry name" value="PTHR12304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01156">
        <property type="entry name" value="IU_nuc_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53590">
        <property type="entry name" value="SSF53590"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01247">
        <property type="entry name" value="IUNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IU_nuc_hydro" evidence="3">
        <location>
            <begin position="5"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="312" mass="34169" checksum="2A4402B4D8D9E72E" modified="2010-01-19" version="1">MLLPIICDCDPGHDDAIALILALSRHELDVKAVTTSAGNQTPDKTLNNALRILTLLNRTDIEVAGGAKKPLSRDLIIAPDVHGESGLDGPELPDTKCKASSLTAFELIAKTLQESSEPITLVPTGPLTNIAIFLSAYPHLHRKIKQIVLMGGAAGVGNWSPAAEFNIFVDPEAADIVFKSGIPIVMCGLDVTHQAQIMDQDIERIRAIPNSIAQCVAELLDFFMIYHRNPKWGFEGAPLHDPCTIAWLLKPELFDAQDCYVSIETQGEHTQGMTVVDRYNVTDKKPNAKVLFSLNREGFVDLLVESLEHYNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-12-02" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4W4</accession>
    <name>D0Z4W4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type III secretion spans bacterial envelope protein (YscO)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000197</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000197"/>
    <dbReference type="EnsemblBacteria" id="EEZ39181">
        <property type="protein sequence ID" value="EEZ39181"/>
        <property type="gene ID" value="VDA_000197"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031D8R">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009929">
        <property type="entry name" value="T3SS_YscO"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07321">
        <property type="entry name" value="YscO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0261">Viral envelope protein</keyword>
    <keyword evidence="1" id="KW-0946">Virion</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="57" mass="6882" checksum="3D0D5F2E77D0508F" modified="2010-01-19" version="1">MEQENQRLKERKQEALAADKTKEKFIQLNEQEIAEQARQVQYQEELEQEEFRSVVVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4Z3</accession>
    <name>D0Z4Z3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ADP-ribosyltransferase toxin aexT (Exoenzyme T)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000226</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306661.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39210">
        <property type="protein sequence ID" value="EEZ39210"/>
        <property type="gene ID" value="VDA_000226"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031X91">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="258799at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003537">
        <property type="entry name" value="YopE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014773">
        <property type="entry name" value="YopE_GAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037168">
        <property type="entry name" value="YopE_GAP_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03545">
        <property type="entry name" value="YopE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01372">
        <property type="entry name" value="YERSINIAYOPE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47233">
        <property type="entry name" value="SSF47233"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0843">Virulence</keyword>
    <feature type="domain" description="YopE" evidence="3">
        <location>
            <begin position="128"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="198"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="514" mass="54919" checksum="B67EE4919E1914E9" modified="2010-01-19" version="1">MTNIGTIHSSATQVTNVSNHQAELSTQTGTLGDKPVTSIATSKEVQQLAERTESSPITRLKDKIISLLSGAVNAIKELLFTSKDKSVSSVVPTDQIQPLSREEMGKIALKESLKGLTQLDNLSSLDGESLKQQHRELATNNGALRSTVTALQAIRLFGTETQKTTANSILSDMVGGRPFQQWATTGSGEAKDASTFLNEASSEELQAASDKINQLSVQISKLKDELIDHLQPQQTASASEEKPANSVESRYKAYNVLGIGGGRSAKDNSVKTALDAVSFLATRVAPSTIPTLSSESINALQDAIADGTVSFSRIQNGALNKGDLAMIRELALSTVSNQDASYTGELGSIVDSLSHSRSNVGTVMQGIQGFIDMSASQWHAKTADKPEDAIDANAHAKFDRELMKSSFDGMSQSDLKQALAQLEGDFGQNLRGIMDLVAEKVPVSDDAQENPVLISSAMRYGNVIEGLITALKEKLGEPIDTSFADAPMIRDISELTAFEKAALLRVGITEEMMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z559</accession>
    <name>D0Z559_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 10">Phosphoenolpyruvate synthase</fullName>
            <shortName evidence="10">PEP synthase</shortName>
            <ecNumber evidence="6 10">2.7.9.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9 10">Pyruvate, water dikinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">VDA_000109</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 10">Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>ATP + H2O + pyruvate = AMP + 2 H(+) + phosphate + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:11364"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.9.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4 10">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 10">Belongs to the PEP-utilizing enzyme family.</text>
    </comment>
    <dbReference type="EC" id="2.7.9.2" evidence="6 10"/>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306874.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000109"/>
    <dbReference type="EnsemblBacteria" id="EEZ39093">
        <property type="protein sequence ID" value="EEZ39093"/>
        <property type="gene ID" value="VDA_000109"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0574">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1080">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008986">
        <property type="term" value="F:pyruvate, water dikinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006090">
        <property type="term" value="P:pyruvate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008279">
        <property type="entry name" value="PEP-util_enz_mobile_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006319">
        <property type="entry name" value="PEP_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018274">
        <property type="entry name" value="PEP_util_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000121">
        <property type="entry name" value="PEP_util_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023151">
        <property type="entry name" value="PEP_util_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036637">
        <property type="entry name" value="Phosphohistidine_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002192">
        <property type="entry name" value="PPDK_AMP/ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43030">
        <property type="entry name" value="PTHR43030"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00391">
        <property type="entry name" value="PEP-utilizers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02896">
        <property type="entry name" value="PEP-utilizers_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01326">
        <property type="entry name" value="PPDK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000854">
        <property type="entry name" value="PEP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52009">
        <property type="entry name" value="SSF52009"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01418">
        <property type="entry name" value="PEP_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00742">
        <property type="entry name" value="PEP_ENZYMES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00370">
        <property type="entry name" value="PEP_ENZYMES_PHOS_SITE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PPDK_N" evidence="12">
        <location>
            <begin position="18"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilizers" evidence="11">
        <location>
            <begin position="384"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilizers_C" evidence="13">
        <location>
            <begin position="481"/>
            <end position="779"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00021623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00033470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR000854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEZ39093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="786" mass="87314" checksum="340FF72046E879D4" modified="2010-01-19" version="1">MQQNTLWFNKLSMNDVDKVGGKNASLGEMVSNLTNVGVSVPNGFATTSYAFNQFLDYEGLDERIHQLLDELDVEDVEALRKTGATIRQWVVEAPFPVDLEQDIRDNYQELINNHPGISVAVRSSATAEDLPDASFAGQQETFLNVKGIDAVLEATKLVYASLFNDRAISYRVHQGFNHRGISLSAGIQRMVRSDKASSGVMFTLDTESGFDQVVFITSSWGLGEMVVQGAVNPDEFYVHKPMLDAGQHSIVKKTFGSKQIKMIYSGRQELGKQVEIIDTSVEERNSFSLNDKEIEDLAKQAMIIEKHYLRPMDIEWAKDGIDGTLYIVQARPETVCSQNKQNIIERYELSNKADVLAEGRAIGQRIGKGPVRLIHSLDQMPLVQDGDVLVTDMTDPDWEPVMKKASAIVTNRGGRTCHAAIIARELGIPAIVGCGDASTKLADGRYVTVSCSEGETGYVYQGELEFEVKRSSVDELPRLPIKVMMNVGNPDRAFDFAQIPNEGVGLARLEFIINKMIGIHPKALLNFDTQSDDLKEEINKRIRGYKDPIDFYVSKLTEGIATIASAFWPKRVIVRMSDFKSNEYKNLVGGKDYEPVEENPMLGFRGAARYISPVFSDCFELETQAIKRVRNEMGLKNVEIMIPFVRTLSEASSVIDLLAKHDLRRGDQGLKIIMMCELPSNAVLADEFLKYFDGFSIGSNDMTQLTLGLDRDSGDVALLFDERNPAVKAMLKMAIDAATKAGKYVGICGQGPSDHDDFAEWLMDQGISSVSLNPDTIIDTWLKLGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5A3</accession>
    <name>D0Z5A3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Chromosome segregation ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000153</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306996.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000004.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39137">
        <property type="protein sequence ID" value="EEZ39137"/>
        <property type="gene ID" value="VDA_000153"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5033CKJ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1546191at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="197" mass="22138" checksum="A6A36DFE055ED2F9" modified="2010-01-19" version="1">MKLLPLLLMVLLSGCNQSNEKEKPIPPPLPQVTKIIKAPELVEELKAQPTIDDQFSVLYDKFDHILDRSESLTGPDENNDGIRDDIGAFIDALEVEEPVRNALKQEARYFQNNLKYDWSENTDANIDKAMAMGGEFLKVIACQDFVRIPVRDATNTSKTITALTYNTKARTMAYLAYNHLKDGSVSTLLPAEAQYCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5A9</accession>
    <name>D0Z5A9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hemolysin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000159</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005307013.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000004.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39143">
        <property type="protein sequence ID" value="EEZ39143"/>
        <property type="gene ID" value="VDA_000159"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502Z9A8">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="397962at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003020110" evidence="1">
        <location>
            <begin position="20"/>
            <end position="573"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="573" mass="65158" checksum="1C78A2385416D37B" modified="2010-01-19" version="1">MKIKTLTMLIVCCSSNAYAFTQWGGSGLTPMGHEWLTRASALELLNSEDLIKPDPEDPRLNWTQGHAKNLDLEIASNEVSKIKNLKKSDKLYEPKYDAIFSAIVGERWVDIAGFNVIDGFIGQYGPDCFDATAQEPADLQQDHFMRRYDDIGSQGGVSAAKRAQNRFIDHFVNAAMANEKRILVWDGGASSSTQSEVDYNYFLFGRAVHLFQDSFSLEHTVRLPEDNYKKIRQVKGYICSDSSEQHSHSSFTSSDFYDSNDVIWKKKSKSDTGWQSYKPSNMKPAALTALEASKDLWAAFIRTMATNINERETTARKEAQQLIDTWLSFDEEEMLSWYDNEKNRDDTFVTSDNKKGQSQKTCLSNISFKNSDGSKPTPTNIEELASNIEKSRNKCLFNIEPVPGFADLYDPYIKIPYNWQWKSNSWKTPGQDWAPSTPKPDNGEVINILAYDNNQLSADTIANNSKIITSGKKGLDFIKVPSENNGYYFRLNNYPNLFFSYSASADETVKLVNSPKQSEFILIGNKNTYNIKNTYWDQFVWYNKAKKSVHLTSHGNEKNTDSSWTILNKDINN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5F7</accession>
    <name>D0Z5F7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000064</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000006">
        <property type="protein sequence ID" value="EEZ39009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39009">
        <property type="protein sequence ID" value="EEZ39009"/>
        <property type="gene ID" value="VDA_000064"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG50338FQ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="205" mass="24457" checksum="5194649C9859AB57" modified="2010-01-19" version="1">MLRIRFIVSKGYVNYTTGECKPSQKLKLIYKFTDRYEVGADKARRQYAKRIGKARTALIFLESTDSKMLTFWLFATEGEGIVFELEDMKDSRKKSSRISIANGDYELLRLPRPNDKARWTWLVTQEKYNDILQEIKLAIRHKKDKTLRQLHFKIVRIYGFSGMRKQGFALLSYMKKEWIRTRKEEFPFPDSYIGYLKIAKKRKEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5H3</accession>
    <name>D0Z5H3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Conjugative transfer protein TrbG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000080</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TrbG/VirB9 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000006">
        <property type="protein sequence ID" value="EEZ39025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000080"/>
    <dbReference type="EnsemblBacteria" id="EEZ39025">
        <property type="protein sequence ID" value="EEZ39025"/>
        <property type="gene ID" value="VDA_000080"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3504">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06911">
        <property type="entry name" value="VirB9_CagX_TrbG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2500">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010258">
        <property type="entry name" value="Conjugal_tfr_TrbG/VirB9/CagX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014142">
        <property type="entry name" value="TrbG_Ti"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033645">
        <property type="entry name" value="VirB9/CagX/TrbG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038161">
        <property type="entry name" value="VirB9/CagX/TrbG_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03524">
        <property type="entry name" value="CagX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02775">
        <property type="entry name" value="TrbG_Ti"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019454" evidence="3">
        <location>
            <begin position="20"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="290" mass="32314" checksum="AAA67FFE4989C1A5" modified="2010-01-19" version="1">MQKTKLFALGLLVSCSSYANIVPPLSQDSLDFLSPDIPLSTVERAGVKLAQKWINGKTKPITRGDGSVTYFYGAVMPTVVCSPLNLCDIQLQPGEEILPKGLNASDTVRWTITPMVSNSPNDQITHVMVKPTDSGLTSNLVIGTNKRTYNIKLISRQKEWMPTVNFDYPEVISQTLESLYTRTKEAKERKILGNGLSIDDLDFNYKTQGQADFVPIRVYNNSVKTILEMPRSVATGKLPTLLVVNDGRREQINYRYKNGRFIVDGLPKQIILLLGSGKYQKSVLITKGDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-06-02" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5H8</accession>
    <name>D0Z5H8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000085</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000006">
        <property type="protein sequence ID" value="EEZ39030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000085"/>
    <dbReference type="EnsemblBacteria" id="EEZ39030">
        <property type="protein sequence ID" value="EEZ39030"/>
        <property type="gene ID" value="VDA_000085"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031NKY">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="25"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="203" mass="22817" checksum="B9D7C7251837C092" modified="2010-01-19" version="1">MDILRSKSDLRLWVKNKRFTMKKHIKWIILGVVTVPTIGYLFYPQSPAPSPVQPVSQDQNITTPSLPEPPKSQPSIVIQLDSNAEKIIQKSNELVQKKLDDALNKLDIEVRTPMTYQVPDMSKTFLTDEDTGFETPTMNPLDQVQFRGLIGNGKNQTAYLSIADNAPFKVQVGSIFQGIKVTRISPNGIEIRKGKQTRLLKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVL8</accession>
    <name>D0YVL8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protease 4</fullName>
            <ecNumber evidence="3">3.4.21.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Endopeptidase IV</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Protease IV</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Signal peptide peptidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_001586</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the peptidase S49 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298331.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001586"/>
    <dbReference type="EnsemblBacteria" id="EEZ40560">
        <property type="protein sequence ID" value="EEZ40560"/>
        <property type="gene ID" value="VDA_001586"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0616">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1318587at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07023">
        <property type="entry name" value="S49_Sppa_N_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004634">
        <property type="entry name" value="Pept_S49_pIV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004635">
        <property type="entry name" value="Pept_S49_SppA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002142">
        <property type="entry name" value="Peptidase_S49"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01343">
        <property type="entry name" value="Peptidase_S49"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001217">
        <property type="entry name" value="Protease_4_SppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00705">
        <property type="entry name" value="SppA_67K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00706">
        <property type="entry name" value="SppA_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="25"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S49" evidence="6">
        <location>
            <begin position="138"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S49" evidence="6">
        <location>
            <begin position="391"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="206"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR001217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR001217-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="617" mass="67441" checksum="D90E9E3F649EA6E1" modified="2010-01-19" version="1">MKTIFKGIGRVCKAIWNLLSFTRQLVLNLIFLILVGALFFAFYQGDKDTETQPQPGALVLDLSGPIVEQKDPVNPVDSLLSEAMGKEPQQENVLFDIVEAIRAASGDNDIKGLVLNLQNMPETSLTKLRYIAKAITDFKQSGKPVYAYGDNFSQSQYYLASYADKVFMSPDGAILLTGYGSYTLYYKSLLEKLDVTTHVFRVGTYKSAIEPYIRDNMSDAAKEANTVWLNQLWQAYTSDVAKNRNIDAAELTPKLPEFIAALKSVDGDFAKLSVKLGLVDSLMTHPEMTQEFEKTFGTDQDHNFNQISYYDYLASLTDINVPSKNKIAVVIASGAIIDGPQRPGTTGGDTTAELLREARFDNNVKAVILRVDSPGGSAFASELIRNEVDALQKAGKPVVVSMSSVAASGGYWISSSADKIIANPTTITGSIGIFAVMTTFEKGLNKLGIYNDGVGTTPFAGVGVTRALPQGVGEIFQLGVDHGYQRFIGLVSKYRHMSLAQVDKIAQGRVWTGADAKRLGLVDELGDFDTAISAAVDLAKINDYQIEWMQQPLSPMEMFLQQFTTEARTQLLTMVLGDMPKAITPVTEKISADLTSLANFNDPKGQYAFCLNCGTFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVS4</accession>
    <name>D0YVS4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative restriction enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001989</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299105.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001989"/>
    <dbReference type="EnsemblBacteria" id="EEZ40957">
        <property type="protein sequence ID" value="EEZ40957"/>
        <property type="gene ID" value="VDA_001989"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0419">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="538212at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026866">
        <property type="entry name" value="CR006_AAA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13166">
        <property type="entry name" value="AAA_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_13" evidence="3">
        <location>
            <begin position="368"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="811"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="479"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="850" mass="95971" checksum="93012B78E4F121A4" modified="2010-01-19" version="1">MGRVREDIINWLHTQPYWVQLAAQTILKQEEITQDKITEFKELLKTPKGQSCTEALDFGQFKEESSTANQIWIKSIGEVEGIDDLNPRSPLTFEQKLTVVYGNNGSGKSGYTRILKKACGKNNANDLKPNVFKAPPTVSKCAISIDGVSTKKIDWVANSLPIPEISSADIFDSFTGGLYLDNENEVSYVPIDVLLFEKLVFVSTSIKSLLDKEQAQLVKILPNTPVELTQSKYIRAINDRLKADVPEATLREFFNFTNDDENKLNELSERLKGDPSKLKDKKSRELMQLTELTNSVLVASEKVSSLVCEKINESKAKLESAKKIAEQGAKALSDENLLNGIGSQTWKALWVAAKEYSMKEAYADEEAPYIGNDAQCVLCHQPLSDAAKQRFKSFEEHIQGSLEKEVKATQLHFDNLVKKLPSIPTKDTLKTQIAASNLVEEEWLPVLSKIWGEIEKVSEALVKHPEIPNQGFTFDTSLIAALSEKKEVLAKEIENHQKDVIAFNKEKLTNELNDYKAKQWASGYIDAIIQEVKRLEKYRQYEEWGKLLGSSKFTRKAGEVSKQVITDAYVKRFNDELDNLGAKKINVQLSKTRVSKGKVMHKLHLMGVNQNFTRSKSHDILSEGEQRIVSLAAFLADTNGKPQTTPFIFDDPISSLDQSYELYVAKRLVELSEHRQVIVFTHRISLLGALNDLGNPKCVHIRRENWGCGEHGVVPLFAKKPLKALNELKNQRLAQARKLLDSHGTEVYAPMAKSICSDFRILLERVVEVEFLADVVQRHRREVQTKNKISNLAKITIDDCNLIERLMGEYSAHEHSQPSESPVEPPTPEQLDTDINAVIDWHTEFKARKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVS9</accession>
    <name>D0YVS9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001994</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299119.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001994"/>
    <dbReference type="EnsemblBacteria" id="EEZ40962">
        <property type="protein sequence ID" value="EEZ40962"/>
        <property type="gene ID" value="VDA_001994"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5033WZB">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="55241at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="821" mass="92003" checksum="7A94D7E2B8DC62B9" modified="2010-01-19" version="1">MAKSPIASVKKATTPPPPSSNGAAVEQLDMVVVLDNPLGSAKATTTFNLKRLCHKQCDPSQELAIPCRRKMVKKFYKDIIQGMKDGMSHATLIRNIDVFIAYLRGSDTLNVDPFSEDGYKAMHDASWEKVVVATEAKKYIFQYEDGEQLGYKEGTAQSIKVKQDTILNKIGFDVGRLQSSLKQFKTDRRPTTVPYVPNEWQTMLRRLNYYFTNLATRLIAYKDANPTLPPPDVLKDVVIDVVDGKEITIDLKSTIRRGSISANSPFNQAMASGYLLFSYYTAFNTTTILDVRHPISIIKEERAGRTSRTVKVKGYKGRSNSEVRALFESLDESLHVVSNDANEDAGIVVTDIDKRDTNGIEDGVTFIEVLSTLSEIYSTEDFGRLFYIYTTNGVGLFDDHIIPLVAMNLGLYSSSRYGLADYFIKLFYDLYNGNTYPLYSVVNTPLRGKVVNKSLVEPTEAKSLTRRLRSMVFGAIQCLTDVELKGIIMPLEYGEPDDDGNIKVRFKYDDGRDGDFVVPVQYKEFLKKVESYSNAFNPIPTPKNADGTGKVSFKEPYLLPLGAKYNTTQWNTPKEVLGRNFLKDYGLGYDDFYLSLLSSRIRATTSNQEYSPEDNGFSAKEILQNSLETLMVSYLNGHPTENQRMASQGMNSLVRIASGQSRNDAVASLKTELGIPVLAYEEYKARNMPTNPNGVLCDGVARVSGKDGTHYGAKKFANKEIEGADVGDIPCYQYDLCVKCNSAELVDDVHAVYKLISFIDALEDAIHLFPERANVIESRVAAFYSKLDTLPESTREKAEEILDENGRYFMFEEHSSVMQYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVU0</accession>
    <name>D0YVU0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Di-and tricarboxylate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_002021</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299197.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40989">
        <property type="protein sequence ID" value="EEZ40989"/>
        <property type="gene ID" value="VDA_002021"/>
    </dbReference>
    <dbReference type="GeneID" id="57341837"/>
    <dbReference type="eggNOG" id="COG0471">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="626718at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031312">
        <property type="entry name" value="Na/sul_symport_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001898">
        <property type="entry name" value="SLC13A/DASS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00939">
        <property type="entry name" value="Na_sulph_symp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00785">
        <property type="entry name" value="dass"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01271">
        <property type="entry name" value="NA_SULFATE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="63"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="142"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="213"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="255"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="285"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="316"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="347"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="374"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="397"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="436"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="456" mass="48999" checksum="E972F036F6D3E142" modified="2010-01-19" version="1">MTTLALSIKNWLINRNSLIFIADVILFVVLLNTLPFEKNVVIGLSILAFVAVLWLTEAIHVSITAVLVPLLAVGFGIFQTPQALSNFANPIIFLFLGGFALAAALHRQELDKAIADKVLMLAKGRMSVAVFMLFGVTAVLSMWISNTATAAMMLPLVLGVLNKVDAKQERNTYVFVLLGIAYCASIGGIATVVGSPPNAIAAAEVGLSFTGWMAFGLPVTMVLLPITVAILYFMLKPNLNHMFELDHKPVEWNHGKCMTLAIFALTVFLWIFSKPINAMLGGFSKFDTLVALTAIVLLGVSRVVRWKDIEKSTDWGVLLLFGGGICLSNILKATGTSVFLAHSLSEFLAQAGLFFTILVVATFVVFLTEFASNTASAALLVPVFATIAEALGVSPVVLSALIAVAASCAFMLPVATPPNAIVFGSGHIKQSEMMKVGIYLNLACIIALTFFAWFFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVY0</accession>
    <name>D0YVY0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">Signal peptidase I</fullName>
            <ecNumber evidence="3 7">3.4.21.89</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_001261</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>Cleavage of hydrophobic, N-terminal signal or leader sequences from secreted and periplasmic proteins.</text>
            <dbReference type="EC" id="3.4.21.89"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the peptidase S26 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.89" evidence="3 7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297748.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001261"/>
    <dbReference type="MEROPS" id="S26.001"/>
    <dbReference type="EnsemblBacteria" id="EEZ40239">
        <property type="protein sequence ID" value="EEZ40239"/>
        <property type="gene ID" value="VDA_001261"/>
    </dbReference>
    <dbReference type="GeneID" id="57339850"/>
    <dbReference type="eggNOG" id="COG0681">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1741894at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06530">
        <property type="entry name" value="S26_SPase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000223">
        <property type="entry name" value="Pept_S26A_signal_pept_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019758">
        <property type="entry name" value="Pept_S26A_signal_pept_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019757">
        <property type="entry name" value="Pept_S26A_signal_pept_1_Lys-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019756">
        <property type="entry name" value="Pept_S26A_signal_pept_1_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019533">
        <property type="entry name" value="Peptidase_S26"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43390">
        <property type="entry name" value="PTHR43390"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10502">
        <property type="entry name" value="Peptidase_S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00727">
        <property type="entry name" value="LEADERPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="SSF51306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02227">
        <property type="entry name" value="sigpep_I_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00501">
        <property type="entry name" value="SPASE_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00760">
        <property type="entry name" value="SPASE_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00761">
        <property type="entry name" value="SPASE_I_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 7" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_S26" evidence="9">
        <location>
            <begin position="61"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="91"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR600223-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF10502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ40239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="296" mass="33157" checksum="E6B0180BF7554FD2" modified="2010-01-19" version="1">MANTFSIILVLATLVTGIIWALDKFVWAPKRRAKIEAAAANAGDQVDAKTLEQIAPQPSWVESASSMFPVIALIMIFRSFVYEPFQIPSESMMPTLLVGDFILVDKHVYGLRDPVFHDKFLSLGEPKRGDVVVFKYPPQPKIDYIKRVVGLPGDTVRYNGNKQLCIAPKGSDVCTPVPQTDPRQYPPMPGMIELTEQLGNVSHNILINPLRRDRTLAYQPRPGVAEWVVPEGEYFVMGDNRDNSADSRYWGFVPEANLVGKAVAIWISFEFDRSPDSILPSWIPTGVRFNRIGKII</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW27</accession>
    <name>D0YW27_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001290</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297805.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40265">
        <property type="protein sequence ID" value="EEZ40265"/>
        <property type="gene ID" value="VDA_001290"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5032YZS">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="680788at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036086">
        <property type="entry name" value="ParB/Sulfiredoxin_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110849">
        <property type="entry name" value="SSF110849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="408" mass="45674" checksum="2F4F061A14098F15" modified="2010-01-19" version="1">MNDNSEHNQLDEIGDNSLANSISSSLVNKYENKENSSYLASSKVIVDKFSEILTSQRVYDIFKSKSKYYAGIKSVRTSLKHIEIFISPQLARDMLQFSQRGAVNKNNKNRKLNRTKVNKYAEAMKAGKWCLTGEPIIISDDGEILNGHHRLQACLEAGVGFISTVTYGVTDDLSFAHIDVGNTRSRAQVLEMSGVKVSAPILSRVAMLAKAFDMTKNKFNFRGTQGTSFQPAEILSYVEEHEELALSVDFASTIVKRHKLESQISEPIYAFAHYLITQNLKELEFDCLPITPEVYLTRVISGLGLNSEEDIEYQVRNYLQSLVRESTSYALLCKLSAIFKGWNLHLNIPVTGNKVSVKRVAQFKRDADGNKLPLPSAGNINEAFTVPCLAKGTIPKRIHKQSNIQIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW72</accession>
    <name>D0YW72_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">Methionine aminopeptidase</fullName>
            <shortName evidence="2">MAP</shortName>
            <shortName evidence="2">MetAP</shortName>
            <ecNumber evidence="2 3">3.4.11.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Peptidase M</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">map</name>
        <name evidence="5" type="ORF">VDA_001357</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 2">Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 3">
            <text>Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.</text>
            <dbReference type="EC" id="3.4.11.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 3">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <cofactor evidence="2 3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="2 3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="2 3">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="2 3">Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.18" evidence="2 3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297913.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001357"/>
    <dbReference type="EnsemblBacteria" id="EEZ40332">
        <property type="protein sequence ID" value="EEZ40332"/>
        <property type="gene ID" value="VDA_001357"/>
    </dbReference>
    <dbReference type="GeneID" id="57339734"/>
    <dbReference type="eggNOG" id="COG0024">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1285136at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046914">
        <property type="term" value="F:transition metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070084">
        <property type="term" value="P:protein initiator methionine removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01086">
        <property type="entry name" value="MetAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01974">
        <property type="entry name" value="MetAP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001714">
        <property type="entry name" value="Pept_M24_MAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002467">
        <property type="entry name" value="Pept_M24A_MAP1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00599">
        <property type="entry name" value="MAPEPTIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="SSF55920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00500">
        <property type="entry name" value="met_pdase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00680">
        <property type="entry name" value="MAP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 3" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M24" evidence="4">
        <location>
            <begin position="12"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="119"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="216"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="275" mass="30548" checksum="339DE6897BD1C496" modified="2010-01-19" version="1">MSIKIKTAEEIEKMRVAGRLAAEVLEMIEPHVKAGVTTEELDRICHDYITKEQGAIPAPLNYHGYPKSVCTSINHIVCHGIPSAIDENMGSKYSKPAVLQDGDIINIDVTVIKDGYHGDTSRMFEVGEVSMEDKRLCRVAQESLYIGMKKVKPGATVGDIGTAIQKFIKNGTSRFSIVKDYCGHGIGNEFHEEPQVVHYKNNDRTVLKEGMCFTIEPMINAGKFGCVTDDDDGWTVYTVDGKKSAQWEHTLLVTKDGCEVLTLRSDESIPRLMHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW83</accession>
    <name>D0YW83_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cysteine desulfurase</fullName>
            <ecNumber evidence="4">2.8.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_001342</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[sulfur carrier]-H + L-cysteine = [sulfur carrier]-SH + L-alanine</text>
            <dbReference type="Rhea" id="RHEA:43892"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="EC" id="2.8.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.7" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297885.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001342"/>
    <dbReference type="EnsemblBacteria" id="EEZ40317">
        <property type="protein sequence ID" value="EEZ40317"/>
        <property type="gene ID" value="VDA_001342"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0520">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="446447at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031071">
        <property type="term" value="F:cysteine desulfurase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006534">
        <property type="term" value="P:cysteine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06453">
        <property type="entry name" value="SufS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022471">
        <property type="entry name" value="Cys_desulphurase_CdsA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010970">
        <property type="entry name" value="Cys_dSase_SufS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016454">
        <property type="entry name" value="Cysteine_dSase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005572">
        <property type="entry name" value="NifS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03392">
        <property type="entry name" value="FeS_syn_CsdA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01979">
        <property type="entry name" value="sufS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_5" evidence="6">
        <location>
            <begin position="27"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="406" mass="44063" checksum="312A449044183874" modified="2010-01-19" version="1">MTSQFNVDAIVAQFPALNDSSNSHAMVYLDSAATAQKPQVVIDTLTRYYSGHNANVHRGSHSLTANATALFEQARTKVQQFLHAQSSKEIIWTRGATEALNLIAQTYGCQNLQVGDEILVSELEHHANIVPWQMIAEQTGAVVKKIPMHSDCTLDMDAYNQLLSHKTKIVAVAHMSNVTGTRNPIEQMIQLAHQYGAVTVIDGAQGIAHEAVDVQTLDADFYVFSGHKIYAPAGIGVLYGKQALLEAMPPWHGGGKMVEKVSFDGTTYAQLPGKFEAGTPNVAGSLALAAAITWLQSLDREAAEAYVLQLRQKAINGIKEIEDLRIIGLQPNASLFSFVVDGVHHQDIATLLDQQGIALRAGHHCAHPMLDALGLSGTLRVSLAMYNTEHDVERFIAALKKACDLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWB6</accession>
    <name>D0YWB6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Diguanylate cyclase (GGDEF domain) with PAS/PAC sensor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001379</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297968.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001379"/>
    <dbReference type="EnsemblBacteria" id="EEZ40354">
        <property type="protein sequence ID" value="EEZ40354"/>
        <property type="gene ID" value="VDA_001379"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2199">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GGDEF" evidence="1">
        <location>
            <begin position="166"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="286" mass="33258" checksum="6CDCF46B50D98BA5" modified="2010-01-19" version="1">MDSKLRDYTTAPLFTHQKSSFLGADTRLLFLQQLQGKLDLYDVFQIFTQEIDKYIDVSKLSWHFDNECALIKSTDMPKYHTYCFSLSFDERVLGELHYQTPYTLEPEEQTLLHHYHRLFAGSLNNALEFRRIKKMALRDHLSDLGNRACFEQDIHHALAISERRAVGLTLVIFDLDNFKQVNDRYGHLNGDKVIRSFSKALKESVRASDRCYRLGGDEFIALLQPSTEQSAEKVTLRVIEALSIHPILQHFNIGTSFGYANYHDGDTSASLIERADRRLYYHKRNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWF9</accession>
    <name>D0YWF9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Lipoyl synthase</fullName>
            <ecNumber evidence="6">2.8.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Lip-syn</fullName>
            <shortName evidence="6">LS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Lipoate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Lipoic acid synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Sulfur insertion protein LipA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">lipA</name>
        <name evidence="8" type="ORF">VDA_001418</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>[[Fe-S] cluster scaffold protein carrying a second [4Fe-4S](2+) cluster] + 4 H(+) + N(6)-octanoyl-L-lysyl-[protein] + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = (R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + 2 5'-deoxyadenosine + [[Fe-S] cluster scaffold protein] + 4 Fe(3+) + 2 hydrogen sulfide + 2 L-methionine + 2 reduced [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:16585"/>
            <dbReference type="Rhea" id="RHEA-COMP:9928"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:14568"/>
            <dbReference type="Rhea" id="RHEA-COMP:14569"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:33722"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:78809"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="EC" id="2.8.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="6">Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Protein modification; protein lipoylation via endogenous pathway; protein N(6)-(lipoyl)lysine from octanoyl-[acyl-carrier-protein]: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the radical SAM superfamily. Lipoyl synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.8" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001418"/>
    <dbReference type="EnsemblBacteria" id="EEZ40392">
        <property type="protein sequence ID" value="EEZ40392"/>
        <property type="gene ID" value="VDA_001418"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0320">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00538">
        <property type="reaction ID" value="UER00593"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016992">
        <property type="term" value="F:lipoate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102552">
        <property type="term" value="F:lipoyl synthase activity (acting on glycine-cleavage complex H protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102553">
        <property type="term" value="F:lipoyl synthase activity (acting on pyruvate dehydrogenase E2 protein)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009249">
        <property type="term" value="P:protein lipoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00206">
        <property type="entry name" value="Lipoyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031691">
        <property type="entry name" value="LIAS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003698">
        <property type="entry name" value="Lipoyl_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10949">
        <property type="entry name" value="PTHR10949"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16881">
        <property type="entry name" value="LIAS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005963">
        <property type="entry name" value="Lipoyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00271">
        <property type="entry name" value="lipoyl_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00510">
        <property type="entry name" value="lipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0408">Iron</keyword>
    <keyword evidence="5 6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Radical SAM core" evidence="7">
        <location>
            <begin position="63"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="291"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ40392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="304" mass="34346" checksum="F4A58D572FEF85D6" modified="2010-01-19" version="1">MALIPVRNVAEEAPKEVLRKPEWMKIKLPSDSQRIQDIKAAMRKNKLHSVCEEASCPNLAECFNHGTATFMILGAICTRRCPFCDVAHGRPLPPSAEEPSHLAQTIADMNLRYVVVTSVDRDDLRDGGAKHFADCTREIRAKSPNIRIETLVPDFRGRMDRALEELQDNPPDVFNHNLETAPRLYRKVRPGANYQWSLDLLKKFKEQHPEIPTKSGLMMGLGETKEEIVEVLKDLRAHGVTMLTLGQYLAPSRHHLPVERYVPPEEFDELKQIALDLGFTHAACGPFVRSSYHADLQAQGVEVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWL6</accession>
    <name>D0YWL6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001507</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298179.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001507"/>
    <dbReference type="EnsemblBacteria" id="EEZ40481">
        <property type="protein sequence ID" value="EEZ40481"/>
        <property type="gene ID" value="VDA_001507"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018689" evidence="2">
        <location>
            <begin position="20"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="75" mass="6833" checksum="BA9A8094C3BA781E" modified="2010-01-19" version="1">MKKTAIVAIAALFASSAFAATETAGTAAGTAGATTAAAGATTAVVVGAATAVAAIAAASSDSNDTISNTTVTANK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWM3</accession>
    <name>D0YWM3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glyco_trans_2-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001514</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298193.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001514"/>
    <dbReference type="EnsemblBacteria" id="EEZ40488">
        <property type="protein sequence ID" value="EEZ40488"/>
        <property type="gene ID" value="VDA_001514"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031NZK">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2142097at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="72"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="271" mass="31574" checksum="3E96A2050D85D7D3" modified="2010-01-19" version="1">MIRKIKEIFFKIRYFIFSRTIRSHEYNKLLFEIEGISGDLERLSFDNKISNKLDYLQSSKELYPSVSAIYRVKNCQEYIESSILSIVPLASEIIIIDNDSNDSTLSICKRLKEELKNIVEIKIYSYKQKVEIAGNGYINRIEKNPAGSLSKFYEYSFSKGSCDYLMKCDAHCIFTLSGIEEIRTMLNRGIDVISFTGTEIYGKTFSYEPSIFSREKSGYKFVDCEQWEKLSFESKNRKLIKKPIFIHLKRLCLSKYIGCNSSESNIIKKYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWR4</accession>
    <name>D0YWR4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thioredoxin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001461</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298101.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001461"/>
    <dbReference type="EnsemblBacteria" id="EEZ40435">
        <property type="protein sequence ID" value="EEZ40435"/>
        <property type="gene ID" value="VDA_001461"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3118">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1630944at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="284" mass="31821" checksum="A8AA28FB7D2DF868" modified="2010-01-19" version="1">MNSSSVIEITEQNLQQVLEQSMSSVVVISFWAPSMPETIEVNRTLEQISQDYPQLMTLATLDCERQPMVAGQFGVRGLPTVAVFKNGQPVDGSAGPQTEQSLREMLGKYLPSPEELALKHALSLVDQKDYLQALPTLRQLAPQFPQDNIVNLAIAECLLETAQFNAAEEILNQIPMQDQDAKYKGLLAKLELHKEAADSPEIRELEQKWQLEPNNFEVGYELAIQYSQANRNEEALEILLSILKKDLNFADGQAKKSMLDLLAALGQGNTLASRYRRQLYALLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWT6</accession>
    <name>D0YWT6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">YcaO domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001481</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298132.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001481"/>
    <dbReference type="EnsemblBacteria" id="EEZ40455">
        <property type="protein sequence ID" value="EEZ40455"/>
        <property type="gene ID" value="VDA_001481"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1944">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1068793at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003776">
        <property type="entry name" value="YcaO-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041080">
        <property type="entry name" value="YcaO_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02624">
        <property type="entry name" value="YcaO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18381">
        <property type="entry name" value="YcaO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00702">
        <property type="entry name" value="TIGR00702"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51664">
        <property type="entry name" value="YCAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YcaO" evidence="1">
        <location>
            <begin position="59"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="582" mass="65927" checksum="EB60EF8A2444846F" modified="2010-01-19" version="1">MKTFIPGKDAALEESIERFQTQLKNLGFNIEEASWLNPVPNVWSVHIRDVDAPMNFTNGKGATKKAALASALGEYFERLSTNYFYADYYLGQDIANSEFVHYPNEKWFPIDFEENLPPEGILDERLTQFYDPTMELLGTDLVDLQSGNMERGVCCLPFERQSDNETVYIPMNIIGNLYVSNGMSAGNTKMETRVQGMSEIFERAVKNRIIAERISLPEIPAEVIAQYPSIKESIDCLEAEGFPIFCFDASLGGQYPVICVVLMNQDNNTCFASFGAHPSFEVSFERTVTELLQGRGLKDLDVFPEPSFDDEEVGDHHNLETHFIDSSGLISWDLFKQEADFEFVHWDFSGTTEQEFTRLLGMFHQEGTDVYISDYNHLGVDCCRIIVPGWSEIYPVEELIEANNNVAMELRETFLALPSVEWDSEQYAEMYSILEEEGFDDFNRLYEIIGLVPDAGSAWQTLRIGELKCLLALAGGDLELALEHASWCVDYNVSTYSKERARFFRCLVASLKLALDEERDPAQYKHAFERQFGTETVAAAWGSIEGTVRFYGLTAGDLSMSQFSAHQKLLASYQKLQAAKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWW1</accession>
    <name>D0YWW1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ATP-dependent Clp protease ATP-binding subunit ClpX</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">clpX</name>
        <name evidence="7" type="ORF">VDA_001550</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the ClpX chaperone family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4 5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001550"/>
    <dbReference type="EnsemblBacteria" id="EEZ40524">
        <property type="protein sequence ID" value="EEZ40524"/>
        <property type="gene ID" value="VDA_001550"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1219">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00175">
        <property type="entry name" value="ClpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004487">
        <property type="entry name" value="Clp_protease_ATP-bd_su_ClpX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046425">
        <property type="entry name" value="ClpX_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010603">
        <property type="entry name" value="Znf_CppX_C4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00382">
        <property type="entry name" value="clpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51902">
        <property type="entry name" value="CLPX_ZB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 4 5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="ClpX-type ZB" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="88"/>
            <end position="95"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="392" mass="43091" checksum="D639A34343A1D5C8" modified="2010-01-19" version="1">MYICDECVDLCNDIIREEIKEVLPKRDGSELPTPQEIRHNLDDYVIGQEHAKKVLAVAVYNHYKRLRNGDTNSDGVELGKSNILLIGPTGSGKTLLAETLARMLDVPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDVAKAERGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQVDTSKILFICGGAFAGLDKVIEQRVATNTGIGFGAEVRSKDESRTLTDLFLQVEPEDLVKFGLIPEFIGRLPVTATLTELDEDALVQILREPKNALTKQYGALFELEGAELEFRDDALVAIARKAMERKTGARGLRSIVEAVLLDTMYELPSTKGVSKVVIDESVIKGESEPLLIYENTENQAAGAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWZ5</accession>
    <name>D0YWZ5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002048</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002048"/>
    <dbReference type="EnsemblBacteria" id="EEZ41016">
        <property type="protein sequence ID" value="EEZ41016"/>
        <property type="gene ID" value="VDA_002048"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031ZEW">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="68" mass="7498" checksum="B9859010109C1711" modified="2010-01-19" version="1">MRDAGGSVLKEDYENEIAICIASVKGFKDKVITRIESAIPSATPQQLEDLETLLNFDLKAISDELETI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX12</accession>
    <name>D0YX12_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299311.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002060"/>
    <dbReference type="EnsemblBacteria" id="EEZ41028">
        <property type="protein sequence ID" value="EEZ41028"/>
        <property type="gene ID" value="VDA_002060"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031N3S">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1454656at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006498">
        <property type="entry name" value="Tail_tube"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04985">
        <property type="entry name" value="Phage_tube"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="163" mass="17553" checksum="592060F85C1798E2" modified="2010-01-19" version="1">MADRIRMRITAQVESVPLMNEIVDFTPPEVKSKLANNEGAFVASEDTVGLEKLNWTLKVKGEHGVLSRSLGQYTMGNAQINVVEKGKSTDGIPYVESYSMYGPITGIKKEAVKMGEKPTITIEGTCKAYTQHDTGILVHDINVNTGKTVIGGVDLMALAGIGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX14</accession>
    <name>D0YX14_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Tail tape measure protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_002062</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299316.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002062"/>
    <dbReference type="EnsemblBacteria" id="EEZ41030">
        <property type="protein sequence ID" value="EEZ41030"/>
        <property type="gene ID" value="VDA_002062"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5283">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="564227at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010090">
        <property type="entry name" value="Phage_tape_meas"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10145">
        <property type="entry name" value="PhageMin_Tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01760">
        <property type="entry name" value="tape_meas_TP901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PhageMin_Tail" evidence="3">
        <location>
            <begin position="283"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="648"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="26"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="649"/>
            <end position="663"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="969" mass="101214" checksum="B96C233731D0A004" modified="2010-01-19" version="1">MSEKISFVLDATVNGLQDIVSTTSATERLTQALESQRGEVKSLNSQLRNIKGFESAELKAEKLAAQLVETKKTMSRLDDEIIQSKKSTTQLRGEYSLTQNEIRGLNAQIATASDERLVSLKNQLKATELRLESLNVDIHQSKAHTNSLSVAYKRASGKVETLTGRQVKQSATLNKLKQSLHNAGISTDHLGEEQRRLKLQTDKATASLEKQNAHLKEMQSIQGRIDSRKAKLGELGSQATGLAAAAAPIAGSIWTAVKNESSFADVKKVVDMNDEQAKELQSWALKTSTTTPMSANDVNTMLAAGGQSGIADINELKEFVLDSSKMGVAFDMEAGQAGETLSVFKAALGIDQKGAMNVAGLANYLSNNSNAKAKDIAGVMAREGASAKTGGFSINESTALSASLLSLGMGEERAATALKNISGRLTLGDASSGNQKKAMAAIGLDASDIAANMQKDASGTLIHVLEALNQAPEEDKSALLSQIFGEEAKGAVASLSGNMENFSKLLKLSKENSSVHLNSLDKEYHSRISTTESGIDMFVNKLNRLSVVFGTALLPALNWVLEPLGKGVDLLADFAQENEGVTQAVGLGVAAFIGLKGALLAGKALSLVFGNSMDKTRLFTKGLNRETQDGGRIAALAARRWRSLNEAVAASRGPTSSGGGLGQESRRRTKRSRIRRSSRKRGLGRVIDTVANSRIAQNLSSGVQSLLGSGKNPIQAMVAPLPAAVPMVRSSSSGLGNIVNGVTESRIGKGVSAGSKSLLGHVRHNPMGSLLAVAGSGLALDPMADMASDVIGIGTDIAEKAGKTGLTKVLKPLGMAMSATSVIDGVAHGDMEKAGGALGDLGGSMGGGALGATIGTMIFPGVGTAIGGLLGSIAGGMGGEMLGSWFGRKLDSPEETAKKVEAVQSQEASAKQSPPVTYSPSFQIHAAPGQDPKVIAQEVSKQINHQLAALMGENTVSTQFSYAAIDRDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX17</accession>
    <name>D0YX17_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Phenylalanine--tRNA ligase alpha subunit</fullName>
            <ecNumber evidence="13">6.1.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Phenylalanyl-tRNA synthetase alpha subunit</fullName>
            <shortName evidence="13">PheRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">pheS</name>
        <name evidence="15" type="ORF">VDA_001884</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + H(+) + L-phenylalanyl-tRNA(Phe)</text>
            <dbReference type="Rhea" id="RHEA:19413"/>
            <dbReference type="Rhea" id="RHEA-COMP:9668"/>
            <dbReference type="Rhea" id="RHEA-COMP:9699"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58095"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78531"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="13">Binds 2 magnesium ions per tetramer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 13">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.20" evidence="13"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298874.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001884"/>
    <dbReference type="EnsemblBacteria" id="EEZ40852">
        <property type="protein sequence ID" value="EEZ40852"/>
        <property type="gene ID" value="VDA_001884"/>
    </dbReference>
    <dbReference type="GeneID" id="57341995"/>
    <dbReference type="eggNOG" id="COG0016">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="469058at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004826">
        <property type="term" value="F:phenylalanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006432">
        <property type="term" value="P:phenylalanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00281">
        <property type="entry name" value="Phe_tRNA_synth_alpha1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004529">
        <property type="entry name" value="Phe-tRNA-synth_IIc_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004530">
        <property type="entry name" value="Phe-tRNA-synth_IIc_mito"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004188">
        <property type="entry name" value="Phe-tRNA_ligase_II_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022911">
        <property type="entry name" value="Phe_tRNA_ligase_alpha1_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002319">
        <property type="entry name" value="Phenylalanyl-tRNA_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010978">
        <property type="entry name" value="tRNA-bd_arm"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11538:SF41">
        <property type="entry name" value="PTHR11538:SF41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02912">
        <property type="entry name" value="Phe_tRNA-synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01409">
        <property type="entry name" value="tRNA-synt_2d"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46589">
        <property type="entry name" value="SSF46589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00468">
        <property type="entry name" value="pheS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 13 15" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="9 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 13 15" id="KW-0436">Ligase</keyword>
    <keyword evidence="10 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11 13" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="14">
        <location>
            <begin position="116"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="252"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEZ40852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="327" mass="37278" checksum="1282D15C89313235" modified="2010-01-19" version="1">MQHLDEIIANATAAIEQADSLVALDEVRVQFLGKKGELTLQLQSLGKLPPEERRTAGQEINKAKQVVQTLLVERKDALQRAELEAKLAAETIDVSLPGRRIENGGIHPVTRTIERIESFFGELGFTTEAGPEIEDAFHNFDALNIAEDHPARTDHDTFFFNPELMLRTHTSGVQIRTMEQNQPPLRFIAPGRVYRNDYDQTHTPMFHQVEGMLVDENVNFAQLKGIIHDFLCNFFEEDLEIRFRPSYFPFTEPSAEVDVKGKNGKWLEVLGCGMVHPNVLRSVNIDPEKYSGFAFGMGVERLTMLRYGVNDLRAFFENDLRFLKQFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX86</accession>
    <name>D0YX86_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Anhydro-N-acetylmuramic acid kinase</fullName>
            <ecNumber evidence="1">2.7.1.170</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">AnhMurNAc kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">anmK</name>
        <name evidence="2" type="ORF">VDA_001945</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>1,6-anhydro-N-acetyl-beta-muramate + ATP + H2O = ADP + H(+) + N-acetyl-D-muramate 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:24952"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58690"/>
            <dbReference type="ChEBI" id="CHEBI:58722"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.170"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-sugar metabolism; 1,6-anhydro-N-acetylmuramate degradation.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cell wall biogenesis; peptidoglycan recycling.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the anhydro-N-acetylmuramic acid kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.170" evidence="1"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298989.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001945"/>
    <dbReference type="EnsemblBacteria" id="EEZ40913">
        <property type="protein sequence ID" value="EEZ40913"/>
        <property type="gene ID" value="VDA_001945"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2377">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="736294at2"/>
    <dbReference type="UniPathway" id="UPA00343"/>
    <dbReference type="UniPathway" id="UPA00544"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097175">
        <property type="term" value="P:1,6-anhydro-N-acetyl-beta-muramic acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006040">
        <property type="term" value="P:amino sugar metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009254">
        <property type="term" value="P:peptidoglycan turnover"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01270">
        <property type="entry name" value="AnhMurNAc_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005338">
        <property type="entry name" value="Anhydro_N_Ac-Mur_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30605">
        <property type="entry name" value="PTHR30605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03702">
        <property type="entry name" value="AnmK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="1 2" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="10"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="374" mass="40798" checksum="2F849BB1FFD36E28" modified="2010-01-19" version="1">MEKYIGLMSGTSMDGVDAVLVEMDDKQIKLLGHHAFPMGKNLKQSLLDICLGQPTSLQIIGELDHRLGHLFADAVLALLDHTQTPASEITAIGSHGQTVFHSPQSQYAFTMQIGDANIIAAKTGITTIADFRRKDMALGGQGAPLVPAFHQQLFSVPDLTRVILNIGGIANITVLEPTCAVTGYDTGPGNMLMDAWIQRHLDRSYDKDATWAKTGTVNQPLLTRLMQEPYLQLSAPKSTGRELFNLPWLDMHLSKLEAMNSQPLSLQDIQATLAEYTAVTIADEVRKHGSSTTTKELLVCGGGAHNPLLMERLAMWLPDWDVMTTADRGVDIDNMEAMAFAWLAYRTMHHQPGNLPEVTGAKALTSLGAIYPAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXA5</accession>
    <name>D0YXA5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pseudouridine synthase</fullName>
            <ecNumber evidence="3">5.4.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_001645</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pseudouridine synthase RsuA family.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298433.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001645"/>
    <dbReference type="EnsemblBacteria" id="EEZ40618">
        <property type="protein sequence ID" value="EEZ40618"/>
        <property type="gene ID" value="VDA_001645"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1187">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1037615at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140098">
        <property type="term" value="F:catalytic activity, acting on RNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034470">
        <property type="term" value="P:ncRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1560">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042092">
        <property type="entry name" value="PsdUridine_s_RsuA/RluB/E/F_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000748">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB/E/F"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018496">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00093">
        <property type="entry name" value="TIGR00093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01149">
        <property type="entry name" value="PSI_RSU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PseudoU_synth_2" evidence="5">
        <location>
            <begin position="62"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="215" mass="24684" checksum="AEDE76A6AFA96F60" modified="2010-01-19" version="1">MKPNTPFRQPRRGNNERRASRKINKPKRPRGPRKIILFNKPFNVLTQFSGEPGDITLADFIPVKDVYPAGRLDKDSEGLLVLTNDGILQARLTQPKSKQPKTYWVQVEGAPSEESLQALRKGVELKDGMTLPAGVEVMSEPNIWPRNPPIRERKNIPTTWLAITLKEGRNRQVRRMTAHIGHPTLRLIRYKMADWTVDDLEPGQWREITLETLPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXG0</accession>
    <name>D0YXG0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">JmjC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001639</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298423.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001639"/>
    <dbReference type="EnsemblBacteria" id="EEZ40612">
        <property type="protein sequence ID" value="EEZ40612"/>
        <property type="gene ID" value="VDA_001639"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2850">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1885303at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039994">
        <property type="entry name" value="JmjC_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13096">
        <property type="entry name" value="PTHR13096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08007">
        <property type="entry name" value="Cupin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjC" evidence="2">
        <location>
            <begin position="90"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="377" mass="43277" checksum="6C394FF746B753F1" modified="2010-01-19" version="1">MYQLTFSFEEFLEKYWQKQPVIIKGGFKDFVDPISADELAGLAMEEDIDSRYVARDGDEWDVQHGPLSFDNMPENNWSFLVQSVNYWHEGAARLVTPFRQLPGWLLDDLMISYSTPGGGVGPHIDQYDVFITQGSGKRRWRVGPKKDDYEEEFRHPALRQIKSFEPIIDEVIEAGDILYIPPGFPHDGDTIETAMSFSVGFRSPKKQELLSSFADHIIANDIGDVHYHNPNLPARNNHGAILASEHQDLENMMRSLLDHPELMKRWMGEYLSQNRHELDLVVCDPEYTTEELQQQLFNGETLARLGGLRAFYHADETHIIFINGETFELPDSLDKTGCFLADIESFTAQDLGEYATNTDFMSLLTTLVNLGYWYFKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXI3</accession>
    <name>D0YXI3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Aminodeoxychorismate lyase</fullName>
            <ecNumber evidence="6">4.1.3.38</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_001689</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.38" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298519.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001689"/>
    <dbReference type="EnsemblBacteria" id="EEZ40660">
        <property type="protein sequence ID" value="EEZ40660"/>
        <property type="gene ID" value="VDA_001689"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0115">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1275805at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008696">
        <property type="term" value="F:4-amino-4-deoxychorismate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017824">
        <property type="entry name" value="Aminodeoxychorismate_lyase_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018300">
        <property type="entry name" value="Aminotrans_IV_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043131">
        <property type="entry name" value="BCAT-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="SSF56752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03461">
        <property type="entry name" value="pabC_Proteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00770">
        <property type="entry name" value="AA_TRANSFER_CLASS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="3 5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="269" mass="30390" checksum="B4EC728B43BD20AE" modified="2010-01-19" version="1">MAWVNGQQQHSLSISDRATQYGDGCFTTILVIDGQPQLWDFHLQRLQDTLAYFAISAPNWQHITQEVFVLAQKFKEKGGIKILISRGSGGRGYSGQDCSQTQVIITTFAWPEHYSQWQQQGICLGVCSQRLGLAPMLAGWKHLNRLEQVLLKQEIENNHWLDGLVLDLNGNITETSVANIFWRKGCKVFTPTLKFAGVHGVVRRKVIELIQTLPYQLEFIDAPIEEIMGAEEVFITNALMSLVPINQIENQTFHQRQLLNALIKGLTAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXM3</accession>
    <name>D0YXM3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001764</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298653.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001764"/>
    <dbReference type="EnsemblBacteria" id="EEZ40732">
        <property type="protein sequence ID" value="EEZ40732"/>
        <property type="gene ID" value="VDA_001764"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0586">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1928533at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032816">
        <property type="entry name" value="SNARE_assoc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09335">
        <property type="entry name" value="SNARE_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="163"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="190" mass="21982" checksum="564648906BD4A71F" modified="2010-01-19" version="1">MIKDWIWLQLDNPLILFFSIIFISYIWEDAALFLAAGLYLQDELSFSTAYLSIFIGLMSGDYCVYLLGRTAKHHRSLYRYISSKPYWQKIQSLCSTKSYQTIFIARCLPGFRTITYMVLGYIQLPHNLMIKGLIFSGAIWISAIFALAYIFKQLVLDHPNLATLLLGIFLLITLSLIYLLKKNIREKTAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXT1</accession>
    <name>D0YXT1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">VDA_002094</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299416.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002094"/>
    <dbReference type="EnsemblBacteria" id="EEZ41062">
        <property type="protein sequence ID" value="EEZ41062"/>
        <property type="gene ID" value="VDA_002094"/>
    </dbReference>
    <dbReference type="GeneID" id="57341782"/>
    <dbReference type="eggNOG" id="COG0784">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004721">
        <property type="term" value="F:phosphoprotein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="PAC" evidence="11">
        <location>
            <begin position="266"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="9">
        <location>
            <begin position="335"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="10">
        <location>
            <begin position="572"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="8">
        <location>
            <position position="623"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ41062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="693" mass="78429" checksum="BF05501CB020DF96" modified="2010-01-19" version="1">MPSFESEKLQETILDLLRSQERESQLRDENEAILAGVSAMAGANNKRQVFNSLLEVIRKFIFFENAIVLTREDEIAPIQELVSTNYLFEGSVWPVFSTFSRCINGESVALFNPEAVEEFQSLPPDYLRYCKSALVTGVKVSSGDALLIFLHSEKGQFTPKCRRVLDRLRPLVERAIIDIDYRERLQSLVTARTQELIHSQQRFKDFAKTVGDWFWEIDTAFNFTYISSPQLAGHMIDQTNILDIFRDQPELKQKLKEKCEQQEPFEDFEWQLPESEGGLWITFTGTPYFDKNDHFLGYRGTSKNITARKKRLFDLQEARKQAESANSAKSQFLAMMSHEIRTPLNAVLGLMDTLADSGLRQEQMEWVKQMDQSAQLLLTIINDILDLSKIESGNFELTNGEMSITDCINLVVNQLSEQARNKNILLQAEIDQTVPSVICGDKNRIAQIMFNLIGNAIKFTSTGSVRVLARRVEDNIEISVIDTGIGIAKQAQNNLFHPFHQADSSITRKYGGTGLGLAISKHLISKMNGKIELDSSLGIGSCFKVILPIVIPLMTIEVDEPEQYPPSNRCLNILLAEDSITNQMVARLMLEKRGHKVHIVNNGEEALEAIRHGHKKFDLVFMDVSMPLVDGVEATRIVRSEGIEIPIIALTANVMKQDQIEYHEAGMNEFLPKPIRGSELTSILQKYQHIVAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-06-02" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXY4</accession>
    <name>D0YXY4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein ImpA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002147</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002147"/>
    <dbReference type="EnsemblBacteria" id="EEZ41115">
        <property type="protein sequence ID" value="EEZ41115"/>
        <property type="gene ID" value="VDA_002147"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010657">
        <property type="entry name" value="ImpA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017739">
        <property type="entry name" value="T6SS-assoc_VCA0119"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06812">
        <property type="entry name" value="ImpA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16989">
        <property type="entry name" value="T6SS_VasJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03362">
        <property type="entry name" value="VI_chp_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ImpA_N" evidence="2">
        <location>
            <begin position="13"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="482" mass="54044" checksum="1FFD596A7461279F" modified="2010-01-19" version="1">MSSMTTYREQLVNPIEGDDAVGLRIIDDPLLDFIDSQMMKVGSLSHADVQWHEVESCVVNLLSNKTKDIKLLTVLLQCLQHQPTPERFTLSIAVLVDFMSAYWETCHPVAGKRGVLPRKKFFNQICVRTSSATEKLDGTLFDAELKTTLEALVDELEHQASHYQLPLDLVDDIAAKVRRQLSQTPNHAAHQTASQQQMTTSDNHHNSGNSPSPSVSAAPVPKLDIDGSNDRAIRTSLLKVSDFLSDIGGDGIGLSIRLRRFAVWFSINSLPDANQHGETQLMPVSSDRVSEYEDQLARGGDLALWRKVEQCLTVSPYWLDGHYLSYRIAKQLGENEWANTIYEELNRFLTRLPQLATLSFKGKIPFISEPALQWIKDSNTLPNNHKVASVGSWHGKRSEALELAQEGGLSVALAMLNDGLSQSSEPRDAFYWRLLSADIMKSQHLEAMATEQYQTLYHQAKEMSVTDWEPSLLEQLEQHIAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY32</accession>
    <name>D0YY32_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hypothetical esterase of the alpha-betahydrolase superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_002195</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299628.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41163">
        <property type="protein sequence ID" value="EEZ41163"/>
        <property type="gene ID" value="VDA_002195"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4667">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="373926at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07208">
        <property type="entry name" value="Pat_hypo_Ecoli_yjju_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045943">
        <property type="entry name" value="DUF6363"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037483">
        <property type="entry name" value="YjjU-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19890">
        <property type="entry name" value="DUF6363"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="1 2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="3">
        <location>
            <begin position="33"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXGXXG" evidence="2">
        <location>
            <begin position="37"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="2">
        <location>
            <begin position="65"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DGA/G" evidence="2">
        <location>
            <begin position="190"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="67"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="407" mass="46487" checksum="D784E0AC6FEC701D" modified="2010-01-19" version="1">MNHLPFTLSTLESELWQPIAEDFCGKKYQKIALVVQGGGQRGIFTAGVLDAFLEANFDPFQLYIGTSAGALNLSSFISRQEMFGYNFITQYTSQDNFFSLYKYLSQQRSMDLDWALDIVAPDGSMALDFSQAQKTLVGRKAFACATRKDSLQDIYLPMYQDNWRDVLRASCAIPVLYQHPVNIGDLEWVDGGVSAAIPAKEAWRQGADLVVIIRTESLDIELDDESEQSAIQDWKDRLEQGLPEYVEKLNLQESLDKFRVFHSEISERFSQWKNELPWRDLDKTEQELEIEANVTQATESINKKGWLTQDNIERFLKLAGYSRSAEVIEMLTRYYETYKDMNDFIESPPAGLDVIQIAPEAQLKSRALLSNADDLEMDYRQGKLIGREFVKHYGAVLKRPDDLPKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYA1</accession>
    <name>D0YYA1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Choline dehydrogenase</fullName>
            <ecNumber evidence="4">1.1.99.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_002264</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.99.1" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299756.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002264"/>
    <dbReference type="EnsemblBacteria" id="EEZ41232">
        <property type="protein sequence ID" value="EEZ41232"/>
        <property type="gene ID" value="VDA_002264"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2303">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="543793at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008812">
        <property type="term" value="F:choline dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="PTHR11552"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GMC_OxRdtase_N" evidence="3">
        <location>
            <begin position="251"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="216"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="543" mass="59930" checksum="127CA106B2980868" modified="2010-01-19" version="1">MFDYIIVGAGSAGCVLANRLSANSHNKVCLIEAGPQDKHPMIHVPLGLIGMMHSKVMNWRYYTEPEPALNERKLFWPRGKTLGGSSSSNAMCYIRGHASDYDHWASLGNAGWSYQDVLPYFRKAEHQEFGEDIYHGSNGPLHVSELRIKNPLSQAFIKAAKQAGLRYNDDFNGQQQEGVGFYQVTQKNGQRCSSAVAYLREAETRDNLTIITNAMVNKVLIDNGVAVGVEYQQGGEIKAVHARKEVILSGGAINSPQLLMLSGIGDKEHLNAHGIECVADLPGVGQNLQDHLDILVVTRERTFHSVGFSPIAMLRAIKGAFDYWLFRQGNFTTNVAEAGGFLKTDDGLDKPDVQFHFSPCFLDNHGLDLLQTVKHGYSLHACCLRPKSRGVLMLRDSNPQSPPILQPNYLSHPDDIEVMLKGLKVSRQILAQKAFDHYRGKEAFPGKEVATDDELRSFIRQKAESIYHPVGTCKMGNDKAAVVDSCLRVRGIDQLRVVDASIMPTLIGGNTNAPTIMIAEKASDLILQDNIFEESDEITSVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYA5</accession>
    <name>D0YYA5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002268</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299762.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002268"/>
    <dbReference type="EnsemblBacteria" id="EEZ41236">
        <property type="protein sequence ID" value="EEZ41236"/>
        <property type="gene ID" value="VDA_002268"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0500">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1515497at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="1">
        <location>
            <begin position="65"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="269" mass="30855" checksum="2DA398E4F0A2535D" modified="2010-01-19" version="1">MGINNICFSTLYKNHIKQVRPTPRPPEHWDKKAEQLPQKAVNAKDHYVEQFIDFMDFSDAKTLFDMGCGTGSIALSVADWFDDVYAVDYSPKMLEICQHRADTQHVDNIHLINKAWEDSWQEIPQCDIAIASRSTLVQDLEAALIKLNNQAKLRVYTTHTVNDSFIDPEIIRALKREVNSGPNYIYAVNILHELGINPKLNYITNPNSQKTVETYEELEQQVKLGLGSLTDAEQSLLQEYFAKKKALGEVIKKPSRDWAIVYWDVTKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYL8</accession>
    <name>D0YYL8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Regulatory protein CysB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002381</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299992.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002381"/>
    <dbReference type="EnsemblBacteria" id="EEZ41349">
        <property type="protein sequence ID" value="EEZ41349"/>
        <property type="gene ID" value="VDA_002381"/>
    </dbReference>
    <dbReference type="GeneID" id="57341418"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="990666at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08413">
        <property type="entry name" value="PBP2_CysB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037423">
        <property type="entry name" value="CysB_PBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="324" mass="36095" checksum="3C7A59EBB1D590D0" modified="2010-01-19" version="1">MKLQQLRYIVEVVNHNLNVSSTAESLYTSQPGISKQVRLLEDELGIQIFERSGKHLTKVTPAGEEIVRIARDILSRVESIKSVAGEHTHPEVGTLNIATTHTQARYALPDVIQGFTARFPKVSLHMHQGTPSQIADAVAKGTTDFAIATEALHLYQDMIMLPCYHWNRSIVVRSDHPLAKKEKISIHDLANYSLVTYVFGFTGRSELDSAFNRAGLTPKIVFTATDADVIKTYVRLGIGVGVIASMAMDDERDQDLVAIDASHIFAASTTKIGFKKGSFLRTYMYDFMERFAPHLTRNVVDQAIALKSNAEIEEMFSTMELPVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYT4</accession>
    <name>D0YYT4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Aspartate--tRNA ligase</fullName>
            <ecNumber evidence="7">6.1.1.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Aspartyl-tRNA synthetase</fullName>
            <shortName evidence="7">AspRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">aspS</name>
        <name evidence="9" type="ORF">VDA_002447</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + L-aspartate + tRNA(Asp) = AMP + diphosphate + L-aspartyl-tRNA(Asp)</text>
            <dbReference type="Rhea" id="RHEA:19649"/>
            <dbReference type="Rhea" id="RHEA-COMP:9660"/>
            <dbReference type="Rhea" id="RHEA-COMP:9678"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78516"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.12" evidence="7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300109.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002447"/>
    <dbReference type="EnsemblBacteria" id="EEZ41415">
        <property type="protein sequence ID" value="EEZ41415"/>
        <property type="gene ID" value="VDA_002447"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0173">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="226836at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004815">
        <property type="term" value="F:aspartate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006422">
        <property type="term" value="P:aspartyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00044">
        <property type="entry name" value="Asp_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004524">
        <property type="entry name" value="Asp-tRNA-ligase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004115">
        <property type="entry name" value="GAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029351">
        <property type="entry name" value="GAD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22594:SF5">
        <property type="entry name" value="PTHR22594:SF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02938">
        <property type="entry name" value="GAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55261">
        <property type="entry name" value="SSF55261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00459">
        <property type="entry name" value="aspS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 7 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="8">
        <location>
            <begin position="146"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Aspartate" evidence="7">
        <location>
            <begin position="195"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="217"/>
            <end position="219"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="217"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="226"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="448"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="482"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="489"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="534"/>
            <end position="537"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="592" mass="66066" checksum="460247BE51CE5C9E" modified="2010-01-19" version="1">MRTQYCGQLNKSQAGQTVELCGWVNRRRDLGGLIFIDMRDREGIVQVVVDPDMKEVFELANQLRNEFCIRLTGEVRTRPESQVNKDMATGEVEVLASGLEIINRSDVLPLDFNQKNSEEQRLKYRYLDLRRPEMSDRIKLRAKASSFVRRFLDTNGFLDIETPVLTKATPEGARDYLVPSRVHKGNFYALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQPEFTQIDIETSFMSAEQVRAVTEQMITEMWKELLNVDLGEFPIMPFSEAMRRFGSDKPDLRNPLELVDVADIVKDVDFKVFSAPANDEKGRVAVICVPGGAELSRKQIDEYTKFVGIYGAKGLAWMKVNDRAAGLEGVQSPVAKFLNEEVIANLLERTNAQTGDIILFGADSNRVVTESMGALRLKLGEDLGLTDKSAWKPLWVVDFPMFEENEDGSLSAMHHPFTSPLNISPEELKANPAGALSNAYDMVLNGYEVGGGSVRIHNGEMQAAVFDILGIAADEQRLKFGFLLDALKYGTPPHAGLAFGLDRLVMLLCGTENIRDVIAFPKTTAAACLLTDAPSVANPAALEELAIAVKLAKEESAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYV0</accession>
    <name>D0YYV0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">UDP-2,3-diacylglucosamine hydrolase</fullName>
            <ecNumber evidence="10">3.6.1.54</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">UDP-2,3-diacylglucosamine diphosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">lpxH</name>
        <name evidence="12" type="ORF">VDA_002463</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>H2O + UDP-2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosamine = 2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosaminyl 1-phosphate + 2 H(+) + UMP</text>
            <dbReference type="Rhea" id="RHEA:25213"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:57957"/>
            <dbReference type="ChEBI" id="CHEBI:78847"/>
            <dbReference type="EC" id="3.6.1.54"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="10">Binds 2 Mn(2+) ions per subunit in a binuclear metal center.</text>
    </comment>
    <comment type="pathway">
        <text evidence="10">Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 4/6.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell inner membrane</location>
            <topology evidence="10">Peripheral membrane protein</topology>
            <orientation evidence="10">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the LpxH family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallophosphoesterase superfamily. YfcE family.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.54" evidence="10"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300141.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002463"/>
    <dbReference type="EnsemblBacteria" id="EEZ41431">
        <property type="protein sequence ID" value="EEZ41431"/>
        <property type="gene ID" value="VDA_002463"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2908">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1690667at2"/>
    <dbReference type="UniPathway" id="UPA00359">
        <property type="reaction ID" value="UER00480"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019897">
        <property type="term" value="C:extrinsic component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008758">
        <property type="term" value="F:UDP-2,3-diacylglucosamine hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00575">
        <property type="entry name" value="LpxH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024654">
        <property type="entry name" value="Calcineurin-like_PHP_lpxH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043461">
        <property type="entry name" value="LpxH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010138">
        <property type="entry name" value="UDP-diacylglucosamine_Hdrlase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34990">
        <property type="entry name" value="PTHR34990"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PTHR34990:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12850">
        <property type="entry name" value="Metallophos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01854">
        <property type="entry name" value="lipid_A_lpxH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="2 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 10" id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword evidence="3 10" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7 10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9 10" id="KW-0464">Manganese</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos_2" evidence="11">
        <location>
            <begin position="1"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="79"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="41"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="195"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF12850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ41431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="247" mass="28401" checksum="8E650E3099CC5EE1" modified="2010-01-19" version="1">MTTLFISDLHLSADRPDITQCFLSFIEQETQHIDALYVLGDLFEMWIGDDDDSPFHQQIKHAFKQLTDRGTPCYFIHGNRDFLIGKQFAKETGMTLLPEHHVANLYGIPTLILHGDTLCIADEAYQKYRKKVHNPCLQWLFSCLPLSTRQRIGDKMRSGSSQNNQQKSAEIMDVTASEVERVMAQDGVYRMIHGHTHRPDIHELTVNGQPATRIVLGDWYDHGSVLVITPDDYQLETRQFQTEQTLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ83</accession>
    <name>D0YZ83_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Flagellar hook-length control protein FliK</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_002596</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Controls the length of the flagellar hook.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FliK family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300429.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002596"/>
    <dbReference type="EnsemblBacteria" id="EEZ41564">
        <property type="protein sequence ID" value="EEZ41564"/>
        <property type="gene ID" value="VDA_002596"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3144">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1153442at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009424">
        <property type="term" value="C:bacterial-type flagellum hook"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044780">
        <property type="term" value="P:bacterial-type flagellum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001635">
        <property type="entry name" value="Flag_hook_Flik"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021136">
        <property type="entry name" value="Flagellar_hook_control-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038610">
        <property type="entry name" value="FliK-like_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02120">
        <property type="entry name" value="Flg_hook"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01007">
        <property type="entry name" value="FLGHOOKFLIK"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1005">Bacterial flagellum biogenesis</keyword>
    <keyword evidence="6" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6" id="KW-0969">Cilium</keyword>
    <keyword evidence="6" id="KW-0282">Flagellum</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flg_hook" evidence="5">
        <location>
            <begin position="468"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="64"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="250"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="345"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="403"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="542"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="87"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="125"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="256"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="271"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="352"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="542"/>
            <end position="570"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="600" mass="64516" checksum="EEEEBB51F5957728" modified="2010-01-19" version="1">MQLSHLLSQVNAKSHTGSTATTRNEPTDPASRGEEAQFAVSLHSAMDDTSDTQLKTKSQLKYELGGEEALKKEPFKKEGAKAAISSDEVSIESQAPSAVLLSKNTTTKSAASDDSQALLAPDEVGEKSQTSSLSVSPSSIEESSDPQTVAQSMDEGLDVLQQLQQSHSQLNSQLRSKKVLTDQQDAKFGTESVSTEDGGDVLQQLQQSHGQLHGQLHSKEVFTDQQDAKLDTESVSTEDGGDALQQLQQSHGQLHGQLRSKKELTDQQDVKLDTESVSTDVGTAHDTTAPLTTRIDTDTIAASTSTATRNANGDKVLLASKLASTDEVELKHHRSIDTELDSHEFKTTVSGGKESTKELLESQQNKSVHGQNALLASKAELLPQGDAVKAGINHSAALSQAHTQSLLDQSHATDSKEASAQAALQSLSAHQNGASSASSLLGNRQDTSLNNQPPLLLTKEQSGDQLADKVQMMAAKNLKQIDIRLDPPELGRMQIKLSLHDDNQASIQFQVAHQQTRDLIDQAMPRLRELLLQQGMQLAQSSVHQETNQQFSQHFNQQSGQDSSAFGSGGHSDGSHDGHDDGTIIEGYVTTSSDRVDYYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZF4</accession>
    <name>D0YZF4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 9">2-dehydropantoate 2-reductase</fullName>
            <ecNumber evidence="4 9">1.1.1.169</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">Ketopantoate reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">VDA_002667</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>(R)-pantoate + NADP(+) = 2-dehydropantoate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:16233"/>
            <dbReference type="ChEBI" id="CHEBI:11561"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15980"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.169"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Cofactor biosynthesis; (R)-pantothenate biosynthesis; (R)-pantoate from 3-methyl-2-oxobutanoate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the ketopantoate reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.169" evidence="4 9"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002667"/>
    <dbReference type="EnsemblBacteria" id="EEZ41635">
        <property type="protein sequence ID" value="EEZ41635"/>
        <property type="gene ID" value="VDA_002667"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1893">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00028">
        <property type="reaction ID" value="UER00004"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008677">
        <property type="term" value="F:2-dehydropantoate 2-reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003710">
        <property type="entry name" value="ApbA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013752">
        <property type="entry name" value="KPA_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013332">
        <property type="entry name" value="KPR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02558">
        <property type="entry name" value="ApbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08546">
        <property type="entry name" value="ApbA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00745">
        <property type="entry name" value="apbA_panE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0521">NADP</keyword>
    <keyword evidence="7 9 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6 9" id="KW-0566">Pantothenate biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ApbA" evidence="10">
        <location>
            <begin position="3"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="ApbA_C" evidence="11">
        <location>
            <begin position="172"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ41635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="299" mass="34143" checksum="D4808EF5FBFBB4B0" modified="2010-01-19" version="1">MKITIVGAGAIGSLWGHQLNQHHLVQMWTRTDEPHYSLTFKPHDASKLSQRLQLPANNREWLRQSDLVLVTVKAFQVIDALRPIYQDIKPTSLVVIMHNGMGTQHSVTQLLPHHTIAYATTAQAAFKQHDIVTHTGIGQTWLGLLQGEQQQVADWAQQFHHILPPCHCHPNILEPLWLKLAINCAINPLTAIYQCTNGQLDSAEHQQQITAICHEVAQVMSQEVAPITTEELLTRVNQVILATQANYSSMNRDVFHHRTTEIDYITGYLIETARRHHIASPYNEKLWQQIKQLEHHYHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZI0</accession>
    <name>D0YZI0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 14">Inosine-5'-monophosphate dehydrogenase</fullName>
            <shortName evidence="7">IMP dehydrogenase</shortName>
            <shortName evidence="7">IMPD</shortName>
            <shortName evidence="7">IMPDH</shortName>
            <ecNumber evidence="7 14">1.1.1.205</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">guaB</name>
        <name evidence="16" type="ORF">VDA_002693</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 14">
            <text>H2O + IMP + NAD(+) = H(+) + NADH + XMP</text>
            <dbReference type="Rhea" id="RHEA:11708"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="EC" id="1.1.1.205"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="7">Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7 14">Purine metabolism; XMP biosynthesis via de novo pathway; XMP from IMP: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 13">Belongs to the IMPDH/GMPR family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.205" evidence="7 14"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002693"/>
    <dbReference type="EnsemblBacteria" id="EEZ41661">
        <property type="protein sequence ID" value="EEZ41661"/>
        <property type="gene ID" value="VDA_002693"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0516">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0517">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00601">
        <property type="reaction ID" value="UER00295"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003938">
        <property type="term" value="F:IMP dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006177">
        <property type="term" value="P:GMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00381">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01964">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005990">
        <property type="entry name" value="IMP_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015875">
        <property type="entry name" value="IMP_DH/GMP_Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001093">
        <property type="entry name" value="IMP_DH_GMPRt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11911">
        <property type="entry name" value="PTHR11911"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00478">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000130">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01302">
        <property type="entry name" value="IMP_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00487">
        <property type="entry name" value="IMP_DH_GMP_RED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0129">CBS domain</keyword>
    <keyword evidence="3 7 14" id="KW-0332">GMP biosynthesis</keyword>
    <keyword evidence="2 7 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10 14" id="KW-0520">NAD</keyword>
    <keyword evidence="5 7 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 7 11" id="KW-0630">Potassium</keyword>
    <keyword evidence="7 14" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="15">
        <location>
            <begin position="60"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="15">
        <location>
            <begin position="120"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="IMP binding" evidence="7 9">
        <location>
            <begin position="305"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="IMP binding" evidence="7 9">
        <location>
            <begin position="328"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="IMP binding" evidence="7 9">
        <location>
            <begin position="352"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="active site" description="Thioimidate intermediate" evidence="7 8">
        <location>
            <position position="272"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7 8">
        <location>
            <position position="368"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7 10">
        <location>
            <begin position="215"/>
            <end position="217"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 10">
        <location>
            <begin position="265"/>
            <end position="267"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 11">
        <location>
            <position position="267"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 11">
        <location>
            <position position="269"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="270"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 11">
        <location>
            <position position="272"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="382"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="436"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <note>ligand shared between two tetrameric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="437"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <note>ligand shared between two tetrameric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="438"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <note>ligand shared between two tetrameric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000130-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000130-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000130-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000130-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EEZ41661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="454" mass="48264" checksum="5E35DFFACCC89E7C" modified="2010-01-19" version="1">MTKEITLNIPMLSASMDTVTEGRLAIALAQEGGIGFIHKNMSIEQQAAQVRMVKKFEAGVVSEPVTVKPDNTIADVKRLTEENGFAGYPVVTDNNELIGIITGRDVRFVTDLSLKVVEVMTPKEKLASAKEGASREEVEAIMQKHRVEKVLLVDDSFRLKGMITAKDFQKAERKPNACKDERGRLRVGAAVGAGAGNEERVQALVEAGVDVLLIDSSHGHSEGVLQRIRETHKQFPNLPIVGGNVATAEGARALIEAGVSAVKVGIGPGSICTTRIVTGVGVPQITAISEAASIADQYGIPVIADGGIRYSGDLCKAIAAGASCVMVGSMFAGTEEAPGEVELYQGRAYKSYRGMGSLGAMSKGSSDRYFQSDNAADKLVPEGIEGRVAYKGHLKEIVHQQMGGLRSSMGLTGSATIEDLRTKAEFVRISGAGMKESHVHDVTITKEAPNYRLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZI8</accession>
    <name>D0YZI8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin)</fullName>
            <ecNumber evidence="6">1.17.7.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ispG</name>
        <name evidence="7" type="ORF">VDA_002701</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>(2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + H2O + oxidized [flavodoxin] = 2-C-methyl-D-erythritol 2,4-cyclic diphosphate + reduced [flavodoxin]</text>
            <dbReference type="Rhea" id="RHEA:43604"/>
            <dbReference type="Rhea" id="RHEA-COMP:10622"/>
            <dbReference type="Rhea" id="RHEA-COMP:10623"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="ChEBI" id="CHEBI:58483"/>
            <dbReference type="ChEBI" id="CHEBI:128753"/>
            <dbReference type="EC" id="1.17.7.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="6">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 5/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the IspG family.</text>
    </comment>
    <dbReference type="EC" id="1.17.7.3" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300739.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002701"/>
    <dbReference type="EnsemblBacteria" id="EEZ41669">
        <property type="protein sequence ID" value="EEZ41669"/>
        <property type="gene ID" value="VDA_002701"/>
    </dbReference>
    <dbReference type="GeneID" id="57341028"/>
    <dbReference type="eggNOG" id="COG0821">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="665306at2"/>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00096"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046429">
        <property type="term" value="F:4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.413.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00159">
        <property type="entry name" value="IspG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011005">
        <property type="entry name" value="Dihydropteroate_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016425">
        <property type="entry name" value="IspG_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004588">
        <property type="entry name" value="IspG_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045854">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30454">
        <property type="entry name" value="PTHR30454"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04551">
        <property type="entry name" value="GcpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004640">
        <property type="entry name" value="IspG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51717">
        <property type="entry name" value="SSF51717"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56014">
        <property type="entry name" value="SSF56014"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00612">
        <property type="entry name" value="ispG_gcpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3 6" id="KW-0408">Iron</keyword>
    <keyword evidence="4 6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5 6" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 6 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <position position="270"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="273"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="305"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="312"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="373" mass="41005" checksum="679555B0E0B30E64" modified="2010-01-19" version="1">MHNESPIKRRQSSRIYVGNVPIGDGAPIAVQSMTNTRTTDVEATVAQIKALERVGADIVRVSVPTMDAAEAFKLIKQQVNVPLVADIHFDYRIALKVAEYGVDCLRINPGNIGREDRIRAVVDCARDYNIPIRIGVNGGSLEKDIQEKYREPTPDALVESAMRHVDILDRLNFDQFKVSVKASDVFLAVDSYRKLAQQIKQPLHLGITEAGGARAGSVKSAVGLGMLLSEGIGDTLRISLAADPVEEIKVGFDILKSLRIRSRGINFIACPTCSRQEFDVIGTVNQLEQRLEDLITPMDVSIIGCVVNGPGEAEASHLGVAGGNRKSAFYEDGIRQKERFDNDNIIDQLEAKIRAKASMLDMNNRIDVKELEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZK0</accession>
    <name>D0YZK0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cysteine desulfurase IscS</fullName>
            <ecNumber evidence="9">2.8.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">iscS</name>
        <name evidence="12" type="ORF">VDA_002713</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[sulfur carrier]-H + L-cysteine = [sulfur carrier]-SH + L-alanine</text>
            <dbReference type="Rhea" id="RHEA:43892"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="EC" id="2.8.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 9 10">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="9">Cofactor biosynthesis; iron-sulfur cluster biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.7" evidence="9"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300792.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002713"/>
    <dbReference type="EnsemblBacteria" id="EEZ41681">
        <property type="protein sequence ID" value="EEZ41681"/>
        <property type="gene ID" value="VDA_002713"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1104">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="839689at2"/>
    <dbReference type="UniPathway" id="UPA00266"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031071">
        <property type="term" value="F:cysteine desulfurase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044571">
        <property type="term" value="P:[2Fe-2S] cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00331">
        <property type="entry name" value="Cys_desulf_IscS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020578">
        <property type="entry name" value="Aminotrans_V_PyrdxlP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010240">
        <property type="entry name" value="Cys_deSase_IscS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016454">
        <property type="entry name" value="Cysteine_dSase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11601:SF34">
        <property type="entry name" value="PTHR11601:SF34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005572">
        <property type="entry name" value="NifS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02006">
        <property type="entry name" value="IscS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00595">
        <property type="entry name" value="AA_TRANSFER_CLASS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 9" id="KW-0408">Iron</keyword>
    <keyword evidence="8 9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 9" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_5" evidence="11">
        <location>
            <begin position="5"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="9">
        <location>
            <begin position="75"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="9">
        <location>
            <begin position="203"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine persulfide intermediate" evidence="9">
        <location>
            <position position="328"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="243"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" description="via persulfide group" evidence="9">
        <location>
            <position position="328"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
            <note>ligand shared with IscU</note>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="9">
        <location>
            <position position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ41681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="404" mass="44904" checksum="929988AB1F58A9EA" modified="2010-01-19" version="1">MKLPIYFDYSATCPVDPRVAEKMMQCLTMDGTFGNPASRSHRYGWQAEEAVDNAREQIAELLNADPREIVFTSGATESDNLAIKGAAHFYNKKGKHVITCKTEHKAVLDPCRQLEREGYEVTYLAPEANGLIDMAKLRDAMREDTVLVSIMHVNNEIGVIQDIDAIGEMCRENKTIFHVDAAQSAGKLPIDVQKTKVDLISLSAHKMYGPKGIGALYVRRKPRIRLEAQMHGGGHERGFRSGTLPTHQIVGMGEAAHIAKQQMEQDYQHAVTLRNRFLEALGDIEAMTINGDLEHRLPNNLNISFAYVEGESLLMALKDLAVSSGSACTSASLEPSYVLRALGLNDELAHSSIRFSFGRFTTEEEVDYAAAQIKGAVEKLRSMSPLWDMFKEGIDLNTVEWAHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZN1</accession>
    <name>D0YZN1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DNA-3-methyladenine glycosylase</fullName>
            <ecNumber evidence="1">3.2.2.20</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002744</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.2.2.20" evidence="1"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41712">
        <property type="protein sequence ID" value="EEZ41712"/>
        <property type="gene ID" value="VDA_002744"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2818">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008725">
        <property type="term" value="F:DNA-3-methyladenine glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005019">
        <property type="entry name" value="Adenine_glyco"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03352">
        <property type="entry name" value="Adenine_glyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="SSF48150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="191" mass="22015" checksum="8C50275B17929CC4" modified="2010-01-19" version="1">MTTTCAWALSDPLLQQYHDTEWGRIPKDDNALAECFILESMQSGLSWLTVLRKRPAYRAAFLDFDLAKIETELLPLEREPLVEHICQQFDVIKHKGKVAAALNNLALLIEVRKQTPLADFFWRFVDNQSIVNQWQTMTQIPAQTEQSVMMSKQLKKQGFKFIGPVTCYSFMQAVGMVNDHLVDCDCYQDHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZQ9</accession>
    <name>D0YZQ9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Protein GrpE</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">HSP-70 cofactor</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">grpE</name>
        <name evidence="8" type="ORF">VDA_002772</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 4">Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 5">Belongs to the GrpE family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300962.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="SMR" id="D0YZQ9"/>
    <dbReference type="STRING" id="675817.VDA_002772"/>
    <dbReference type="EnsemblBacteria" id="EEZ41740">
        <property type="protein sequence ID" value="EEZ41740"/>
        <property type="gene ID" value="VDA_002772"/>
    </dbReference>
    <dbReference type="GeneID" id="57340950"/>
    <dbReference type="eggNOG" id="COG0576">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1906715at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000774">
        <property type="term" value="F:adenyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042803">
        <property type="term" value="F:protein homodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00446">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.22.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01151">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000740">
        <property type="entry name" value="GrpE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013805">
        <property type="entry name" value="GrpE_coiled_coil"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009012">
        <property type="entry name" value="GrpE_head"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21237">
        <property type="entry name" value="PTHR21237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01025">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00773">
        <property type="entry name" value="GRPEPROTEIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51064">
        <property type="entry name" value="SSF51064"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58014">
        <property type="entry name" value="SSF58014"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01071">
        <property type="entry name" value="GRPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 8" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="36"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ41740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="206" mass="22919" checksum="A6799325024A6F6B" modified="2010-01-19" version="1">MNNEEKKVQDEQLQQDNVETVETESAEQEAVEMTAEELYEARIAELEAALLASEAKANEAKDSALRAMAEGENVRRRAEQEIDKARKFALNKFSEELLPVIDNLERAIEMADKSDEAIKPMLEGVELTLKTMTDTVAKFGLTQINPMGEAFNPEFHQAMSIQESADHAPNSVMFVMQKGYELNGRVIRPAMVMVSKAPAGNIDTQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZR7</accession>
    <name>D0YZR7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Phage integrase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_002780</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300985.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002780"/>
    <dbReference type="EnsemblBacteria" id="EEZ41748">
        <property type="protein sequence ID" value="EEZ41748"/>
        <property type="gene ID" value="VDA_002780"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0582">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="785253at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0075713">
        <property type="term" value="P:establishment of integrated proviral latency"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046718">
        <property type="term" value="P:viral entry into host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044826">
        <property type="term" value="P:viral genome integration into host DNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044068">
        <property type="entry name" value="CB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038488">
        <property type="entry name" value="Integrase_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025166">
        <property type="entry name" value="Integrase_DNA_bind_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004107">
        <property type="entry name" value="Integrase_SAM-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13356">
        <property type="entry name" value="Arm-DNA-bind_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14659">
        <property type="entry name" value="Phage_int_SAM_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51900">
        <property type="entry name" value="CB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0229">DNA integration</keyword>
    <keyword evidence="3" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="2 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1179">Viral genome integration</keyword>
    <keyword evidence="5" id="KW-1160">Virus entry into host cell</keyword>
    <feature type="domain" description="Core-binding (CB)" evidence="8">
        <location>
            <begin position="105"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="Tyr recombinase" evidence="7">
        <location>
            <begin position="209"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="413" mass="47309" checksum="1F36C5C6911E1714" modified="2010-01-19" version="1">MGTKAVRLNQKQIEHAKPKEKDYVLSDGDGLQLRIRTNGSRLWNFNYRHPITKKRINMGLGAFPELSLAQARKLTMDARSLVTQGIDPKDYREQQKIEEQKVSKHTLINVSTQWFELKKETITPNYAEDIWRSLEKHIFPQIANYPISQITAPMIIAILRPIEAKGSLETVKRLTQRLNEIMNYSVNCGLVISNPLSGIKAAFKKPKKENMASLKPDELPELINAIANASIKRTTRCLIEWQLHTMTRPAEASSTRWEEIDLESKIWTIPPERMKKRREHRIPLTEQALLLLETMQPISGHREFVFPSDRDPKKPCNSQTANMALKRMGFAGRLVSHGLRSLASTTLNEQGFEADLIEAALAHVDDNQVRSAYNRTDYLERRIPMMIWWSRHIEEATQGSLSVTGTKQLKVIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZS8</accession>
    <name>D0YZS8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_002791</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301017.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002791"/>
    <dbReference type="EnsemblBacteria" id="EEZ41759">
        <property type="protein sequence ID" value="EEZ41759"/>
        <property type="gene ID" value="VDA_002791"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0210">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="137860at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014017">
        <property type="entry name" value="DNA_helicase_UvrD-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000212">
        <property type="entry name" value="DNA_helicase_UvrD/REP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011528">
        <property type="entry name" value="NERD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11070">
        <property type="entry name" value="PTHR11070"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08378">
        <property type="entry name" value="NERD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13361">
        <property type="entry name" value="UvrD_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0347">Helicase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NERD" evidence="5">
        <location>
            <begin position="17"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="UvrD-like helicase C-terminal" evidence="6">
        <location>
            <begin position="429"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="domain" description="UvrD-like helicase C-terminal" evidence="6">
        <location>
            <begin position="541"/>
            <end position="604"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="622" mass="71356" checksum="F6E69186822A5909" modified="2010-01-19" version="1">MAILIPALSTCLKKMTSGERRFARRLETHLEDDYLCWFDIPVGKKRRYPDFIILHPDRGLLFLEVKDWKLSSISDLTSTQVTLHTDKGLERKANPLEQVRQCTYTVLNKLKSDLQLINHEGKYKGSLVLPYGYGVVLTNITRKQLNDAIPLDAQDTVLPPHLVICKDEMTDSVDIEVFQSQLWGMFNYTFPNQLTFPQIDRIRWHLYPEIRIQSPDQASLFEEEDFEFKHEDFSGNMPDIIKIMDIQQEQLARSLGEGHRVIHGVAGSGKTLILGYRCLHLAALLHKPILVLCFNITLASKLRSFIRDKEIEHKVQVYHFHDWCGQQLRTYHIKLVDGDNAVWERQVDSVIAGVDKGDIPRAQYGAVLIDEGHDFEADWLKLITQMVDPDTNSLLLLYDDAQSIYKHKNGLNFSLSSVGIQAQGRTTILKLNYRNTQEILQFSYQFAQTYFEQADHDDIPVIKPEAAGISGDNPIVRQFPDAESEVCFLVRCIKKWQLDGRLLQNIAILYPSSYMGKKALDALKKAGIDCIWLAKSDYKKKYDPKKNQLAILPIHSSKGLEFDTVVIIDSSHQYQNDDDVSSIVRLLYVGFTRAMKHLLVTYHEENELSESFEKIAKKKAIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZV8</accession>
    <name>D0YZV8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Peptide chain release factor 3</fullName>
            <shortName evidence="6">RF-3</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">prfC</name>
        <name evidence="8" type="ORF">VDA_002821</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002821"/>
    <dbReference type="EnsemblBacteria" id="EEZ41789">
        <property type="protein sequence ID" value="EEZ41789"/>
        <property type="gene ID" value="VDA_002821"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4108">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016149">
        <property type="term" value="F:translation release factor activity, codon specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006449">
        <property type="term" value="P:regulation of translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04169">
        <property type="entry name" value="RF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00072">
        <property type="entry name" value="Rel_fac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004548">
        <property type="entry name" value="PrfC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032090">
        <property type="entry name" value="RF3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038467">
        <property type="entry name" value="RF3_dom_3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041732">
        <property type="entry name" value="RF3_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43556">
        <property type="entry name" value="PTHR43556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16658">
        <property type="entry name" value="RF3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00503">
        <property type="entry name" value="prfC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="7">
        <location>
            <begin position="2"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="11"/>
            <end position="18"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="79"/>
            <end position="83"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="133"/>
            <end position="136"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ41789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="520" mass="58365" checksum="1B798D0DA4736AA6" modified="2010-01-19" version="1">MAKRRTFAIISHPDAGKTTITEKVLLFGNAIQKAGTVKGRGSNQHAKSDWMEMEKERGISVTTSVMQFPYNDCLVNLLDTPGHEDFSEDTYRTLTAVDSCLMVIDAAKGVEDRTRKLMEVTRLRDTPIVTFMNKLDRDIRDPMELLDEVENELNISCAPITWPIGCGKEFKGVYHIHRNETILYSTGQGHTIQELRTIKGLDNPELDEQVGNDLAEQLREELELVIGACPEFDQELFLAGELTPVYFGTALGNFGVDHMLDGLTAWAPQPRPRQANEREVTAEEEKFSGFVFKIQANMDPKHRDRIAFVRIVSGTYTQGMKMNHVRTGKTVSISDAVTFMAGDRARAEQAFAGDIIGLHNHGTIQIGDTFTQGEALKFSGIPNFAPELFRRIRLRDPLKQKQLLKGLVQLSEEGAVQVFRPLQNNDLIVGAVGVLQFDVVVARLKAEYNVEAIYEGVNVATARWVECDDAKKFEDFKRKNQSNLALDGGDNLTYIAPTMVNLNLAKERFPEVDFRATREH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z091</accession>
    <name>D0Z091_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="12 13">DNA primase</fullName>
            <ecNumber evidence="12">2.7.7.101</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">dnaG</name>
        <name evidence="16" type="ORF">VDA_002954</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 13">RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12 13 14">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="12 13 14">Binds 1 zinc ion per monomer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Monomer. Interacts with DnaB.</text>
    </comment>
    <comment type="domain">
        <text evidence="12">Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12 13">Belongs to the DnaG primase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.101" evidence="12"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301414.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002954"/>
    <dbReference type="EnsemblBacteria" id="EEZ41922">
        <property type="protein sequence ID" value="EEZ41922"/>
        <property type="gene ID" value="VDA_002954"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0358">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1071997at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990077">
        <property type="term" value="C:primosome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003896">
        <property type="term" value="F:DNA primase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03364">
        <property type="entry name" value="TOPRIM_DnaG_primases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.980.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00974">
        <property type="entry name" value="DNA_primase_DnaG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016136">
        <property type="entry name" value="DNA_helicase_N/primase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013264">
        <property type="entry name" value="DNA_primase_core_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037068">
        <property type="entry name" value="DNA_primase_core_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019475">
        <property type="entry name" value="DNA_primase_DnaB-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006295">
        <property type="entry name" value="DNA_primase_DnaG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013173">
        <property type="entry name" value="DNA_primase_DnaG_DnaB-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036977">
        <property type="entry name" value="DNA_primase_Znf_CHC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030846">
        <property type="entry name" value="DnaG_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034151">
        <property type="entry name" value="TOPRIM_DnaG_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002694">
        <property type="entry name" value="Znf_CHC2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10410">
        <property type="entry name" value="DnaB_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08278">
        <property type="entry name" value="DnaG_DnaB_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08275">
        <property type="entry name" value="Toprim_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01807">
        <property type="entry name" value="zf-CHC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002811">
        <property type="entry name" value="DnaG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00766">
        <property type="entry name" value="DnaG_DnaB_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00400">
        <property type="entry name" value="ZnF_CHCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01391">
        <property type="entry name" value="dnaG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12 13" id="KW-0235">DNA replication</keyword>
    <keyword evidence="10 12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1 12 13" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 12 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 12 13" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="2 12 13" id="KW-0639">Primosome</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 12 13" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 12 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 12 13" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 12 14" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Toprim" evidence="15">
        <location>
            <begin position="261"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="CHC2-type" evidence="12 14">
        <location>
            <begin position="40"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR002811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR002811-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EEZ41922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="584" mass="66113" checksum="B7F45864B30A8ED2" modified="2010-01-19" version="1">MAGRIPRSFIDDLISRYDIVDVIDSRVKLKKKGKNFGACCPFHNEKTPSFSVSQEKQFYHCFGCGAHGNVLDFVMEFDRLEFVEAIEELASQLGIEVPRENDNGSAPSGPRSAEKRNLYDVMAHIAQFYQSQLRTDEGQLAIDYLKGRGLSGEIVKKFAIGYVPDQWDLVRNRYGRDEASQQALVDMGMLIENDNGRRYDRFRGRVMFPILDRRGRVIGFGGRVLGDGTPKYLNSPETPIFHKGRELYGLHQVLETHREPERILVVEGYMDVVALAQFGVDYAVASLGTSTTSEHIQTLFRQTSTVVCCYDGDRAGREAAWRAMEQALPYLLDGRELKFMFLPDGEDPDTYIRQYGKEEFEHQVSSAMSLIDFMFNSLTEQANMETKEGRSKLMTLAKPLIEKVAGEALREYLINKLGYSLGLPPDQIRLESKRPQQEKPRLVQQNLKRTPMRDVVALLIQNPIFVNQLEFDTQAFEGIEVAGLNLLLTIVEKCRTNPNITTGQLLESWRGSKNEALLARLASWELPLSKDEDSTLDVFLDAMDNVIGQCVQQQIEKLQAKSSTVGLSVEEKQELQSLLLDRPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0A5</accession>
    <name>D0Z0A5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Thiamine transport system permease protein ThiP</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">VDA_002968</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">The complex is composed of two ATP-binding proteins (ThiQ), two transmembrane proteins (ThiP) and a solute-binding protein (ThiB).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="11">Cell membrane</location>
            <topology evidence="11">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301436.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002968"/>
    <dbReference type="EnsemblBacteria" id="EEZ41936">
        <property type="protein sequence ID" value="EEZ41936"/>
        <property type="gene ID" value="VDA_002968"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1178">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1783638at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015888">
        <property type="term" value="P:thiamine transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005947">
        <property type="entry name" value="ThiP_ABC_transpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01253">
        <property type="entry name" value="thiP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="7 11 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="70"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="112"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="175"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="216"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="269"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="310"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="350"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="376"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="441"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="480"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="33"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="307"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ41936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="531" mass="58351" checksum="B91C5D79972E462E" modified="2010-01-19" version="1">MAVVMGALFALISQAKDLSITVIWTDPYLRHVTAFSFKQALYSTLLSVIPAIAIAYAFSRRQFIGRALVLKLFAMTLVLPVLIAVFGLLAIYGKGGIISQWMQHFGLPAPNIYGLSGILLAHVFLNLPLSVRLLLQSLESIPIEHHQLAAHLGITGWSKFRFVAWPRLKQQLPHVVGLVFMLCFTSFAVIMSLGGGPKATTIELAIYQALRYDFDLATGAILALWQIVLCSGLVLLSHYFSQPIAIESGQNKVQPQFENGTLAKWWDGLWIGASLLLVIPPFVAVIVAGLNHEFWHLLQQAELWQAIKNSLTIASCASVIAFVFAVAIILTSRYWRLSSRLWSANTIEMLGTIILLTPGLVLSTGIFLLLRNYTDAYGAAFWVVTLVNALMALPYIIKTLSQPMLHVAQQYNQLCCSLNMSGLSRLYWVEWRLLRYPIAQAVAISFVLSLGDLGAISLFGSQDFQTLPLYLFQLMGSYQMAAASVAALILLLLSFGVFSIIEGILKPNHNAINTTTTASHKVGSTKGSSHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0C5</accession>
    <name>D0Z0C5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TRAP transporter solute receptor TAXI family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002988</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301491.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002988"/>
    <dbReference type="EnsemblBacteria" id="EEZ41956">
        <property type="protein sequence ID" value="EEZ41956"/>
        <property type="gene ID" value="VDA_002988"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2358">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="991310at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011852">
        <property type="entry name" value="TRAP_TAXI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42941">
        <property type="entry name" value="PTHR42941"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16868">
        <property type="entry name" value="NMT1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02122">
        <property type="entry name" value="TRAP_TAXI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0675">Receptor</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018727" evidence="1">
        <location>
            <begin position="25"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="323" mass="34827" checksum="9901C571B87F7899" modified="2010-01-19" version="1">MALKTLISSSAIAATLLLAGQASAQEFITIGTGSVTGVYYPTGGAICKLVNKDRKDHNIRCSVESTGGSIYNINTLRSGELDFGVVQSDWQYHGYNGSSKFKEQGPYPKLRAVFSIHTEPFNIIARADSGIKTLADLKGKRVNIGNPGSGDRATMGVVMDALGWTEKDFKLASELKGSERSQALCDNKIDAFIYMVGHPNGSIKEATTSCNAKLIPVTGEAIEKIIADNPYYTATEVPGNMYQGNDDVESFGVAATLVTSTDVSDDAVYALTKAVFENFDTFKRLHPAFAHLKPQDMVKNGISIPLHPGAIRYYKEAGLLPKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0E3</accession>
    <name>D0Z0E3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidyl-prolyl cis-trans isomerase</fullName>
            <ecNumber evidence="5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_003007</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 4 5">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the FKBP-type PPIase family.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301550.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003007"/>
    <dbReference type="EnsemblBacteria" id="EEZ41974">
        <property type="protein sequence ID" value="EEZ41974"/>
        <property type="gene ID" value="VDA_003007"/>
    </dbReference>
    <dbReference type="GeneID" id="57340543"/>
    <dbReference type="eggNOG" id="COG0545">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1861282at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000774">
        <property type="entry name" value="PPIase_FKBP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036944">
        <property type="entry name" value="PPIase_FKBP_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01346">
        <property type="entry name" value="FKBP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="6">
        <location>
            <begin position="120"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="206" mass="22025" checksum="A1597B3996DB1565" modified="2010-01-19" version="1">MFDVKLDTVETKASYGIGLQMGQQLAHSGLEGLNVAAIAKGIAASLTGEMPEIEVDEINDALRELHMRAEEIRQAQAKAAAAEGEAFLADNALREEVTVTDSGLQYEVLVEGNGEIPTSDKTVRVHYHGTLTDGTVFDSSVSRGQPAEFPVTGVIAGWVEALQLMPVGSKWKLYIPQNLAYGERGAGAAIPPYAALVFEVELLDIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0F6</accession>
    <name>D0Z0F6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Alanine racemase</fullName>
            <ecNumber evidence="3">5.1.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_003020</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>L-alanine = D-alanine</text>
            <dbReference type="Rhea" id="RHEA:20249"/>
            <dbReference type="ChEBI" id="CHEBI:57416"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="EC" id="5.1.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 3 4">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the alanine racemase family.</text>
    </comment>
    <dbReference type="EC" id="5.1.1.1" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301584.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003020"/>
    <dbReference type="EnsemblBacteria" id="EEZ41987">
        <property type="protein sequence ID" value="EEZ41987"/>
        <property type="gene ID" value="VDA_003020"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0787">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="859043at2"/>
    <dbReference type="UniPathway" id="UPA00042">
        <property type="reaction ID" value="UER00497"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008784">
        <property type="term" value="F:alanine racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030632">
        <property type="term" value="P:D-alanine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01201">
        <property type="entry name" value="Ala_racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000821">
        <property type="entry name" value="Ala_racemase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009006">
        <property type="entry name" value="Ala_racemase/Decarboxylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011079">
        <property type="entry name" value="Ala_racemase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001608">
        <property type="entry name" value="Ala_racemase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020622">
        <property type="entry name" value="Ala_racemase_pyridoxalP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00842">
        <property type="entry name" value="Ala_racemase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01168">
        <property type="entry name" value="Ala_racemase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00992">
        <property type="entry name" value="ALARACEMASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01005">
        <property type="entry name" value="Ala_racemase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50621">
        <property type="entry name" value="SSF50621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="SSF51419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00492">
        <property type="entry name" value="alr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00395">
        <property type="entry name" value="ALANINE_RACEMASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3 4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ala_racemase_C" evidence="6">
        <location>
            <begin position="235"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; specific for D-alanine" evidence="3">
        <location>
            <position position="34"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; specific for L-alanine" evidence="3">
        <location>
            <position position="256"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="304"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="3 4">
        <location>
            <position position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR600821-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR600821-52"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="359" mass="38730" checksum="3706C7C77EEA6BC2" modified="2010-01-19" version="1">MKAATAHIDTEALTHNLRQLRTQAPNSKILAVVKANAYGHGLLHVAKSLPTVDAYGAARIEEALTLRAGGIVKPILLLEGFYSPSDLPVLVTNNIHTVVHSIEQLEALEQAKLDGPVVVWLKIDTGMHRLGVRPEQIDEFITRLHACHNVAKPLRYISHFGCADDLQSDVTNQQLETFLALTEGCTGERSLAASAGVLAWPDSHLEWIRPGIVMYGISPFAEPEMSASAYNLKPVMTLTSSLIAVRDVKKGEQVGYGGNWTSERDTKVGVIAIGYGDGYPRSAPNGTPILVNGRIVPMAGRVSMDMLTVDLGPDAQDKVGDEAILWGNGLPAEVVAEHIGTIAYELVTKLTSRVAMTYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0G5</accession>
    <name>D0Z0G5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Sodium-type polar flagellar protein MotX</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_003029</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301637.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003029"/>
    <dbReference type="EnsemblBacteria" id="EEZ41996">
        <property type="protein sequence ID" value="EEZ41996"/>
        <property type="gene ID" value="VDA_003029"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0790">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0966">Cell projection</keyword>
    <keyword evidence="1" id="KW-0969">Cilium</keyword>
    <keyword evidence="1" id="KW-0282">Flagellum</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="209" mass="23899" checksum="30DA3A3D8A5E1D36" modified="2010-01-19" version="1">MKPAVKLWLLSAAIIPIWGWSQGVGDAVPVYSDSQLIHLFETNSQLAQVKADDCQLVQDIIARARRVQSPAYQFLYGDMLAWGVCVPKDAETGLYYMKKAANQGLPAALEQLGRYYATGTLVQQDRDRAILYLREAAAMGNIAARIRLAELLLKDYGSPLDYEDAYRWLYFSVTDNRNQHQRITQLRRRLEHQMPANIIARAKREELLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0Q0</accession>
    <name>D0Z0Q0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Type II secretion system protein N</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">General secretion pathway protein N</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">VDA_003114</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GSP N family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301901.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003114"/>
    <dbReference type="EnsemblBacteria" id="EEZ42081">
        <property type="protein sequence ID" value="EEZ42081"/>
        <property type="gene ID" value="VDA_003114"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5032RTB">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1565792at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022792">
        <property type="entry name" value="T2SS_protein-GspN"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01203">
        <property type="entry name" value="T2SSN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019286" description="Type II secretion system protein N" evidence="10">
        <location>
            <begin position="22"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ42081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="253" mass="27264" checksum="8FFC65F8A2A16FBB" modified="2010-01-19" version="1">MKFKLALGASFGAVFIASAIAHIPASWVWQQAPAVPGLTVTGISGTVWQGRADKVSWQQQSFGQVYWDVNVLDLLTAKVSADVRFGQGSDMALRGRGEVGYTLSGGPYAKQLMVSLPAQQALNYAKLPIPLTATGHLELALQEYQFAVPYCKSLTGTLTWSQPKVGTPMGDLALGQAKADLRCVKGNLQASVKQSSADVSSEWSATLDQRQNYQVSGWFKPGANFPTALGSQLKWLGNPDSKGQYRINQQGRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0R8</accession>
    <name>D0Z0R8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">50S ribosomal subunit assembly factor BipA</fullName>
            <ecNumber evidence="3">3.6.5.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">GTP-binding protein BipA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">bipA</name>
        <name evidence="5" type="ORF">VDA_003132</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>GTP + H2O = GDP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="3">Binds to ribosomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.-" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301957.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003132"/>
    <dbReference type="EnsemblBacteria" id="EEZ42099">
        <property type="protein sequence ID" value="EEZ42099"/>
        <property type="gene ID" value="VDA_003132"/>
    </dbReference>
    <dbReference type="GeneID" id="57340639"/>
    <dbReference type="eggNOG" id="COG1217">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="143460at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03710">
        <property type="entry name" value="BipA_TypA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00849">
        <property type="entry name" value="BipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035651">
        <property type="entry name" value="BipA_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042116">
        <property type="entry name" value="TypA/BipA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006298">
        <property type="entry name" value="TypA_GTP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908:SF8">
        <property type="entry name" value="PTHR42908:SF8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01394">
        <property type="entry name" value="TypA_BipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="3" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Tr-type G" evidence="4">
        <location>
            <begin position="7"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="19"/>
            <end position="24"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="132"/>
            <end position="135"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ42099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="609" mass="67313" checksum="2EC18B5BB5EF847F" modified="2010-01-19" version="1">MSNPQIDKLRNIAIIAHVDHGKTTLVDKLLQQSGTLESRGEAEERVMDSNDIEKERGITILAKNTAINWNDYRINIVDTPGHADFGGEVERIMSMVDSVLLIVDAVDGPMPQTRFVTQKAFAHGLKPILVINKIDRPGARPEWVMDQVFDLFDNLGATDEQLDFQVVYASALNGWATMEEGETGENMEPLFQAIVENVAAPDVDVDGALQMQISQLDYSSYVGVIGVGRVTRGSVVPNQQVCVVGADGTKRNGKVGTVLGYLGLERHDVEKATAGDIIAITGLGELKISDTICDVNTPEALPALSVDEPTVTMTFQVNNSPFAGKEGKYVTSRNILERLQKELVHNVALRVEETEDPDKFRVSGRGELHLSILIENMRREGYELAVSRPEVIIKRDENGDLQEPFETVTIDVMEEHQGGIMENIGLRKGELTDMAPDGKGRVRMDFMMPSRGLIGFQTEFMTLTSGSGLLYHTFDHYGPHKGGNIGQRNNGVLISNATGKALTYALFNLQERGRLFTEHADEVYEGQIIGIHNRSNDLTVNCLKGKQLTNVRASGTDEAQVLSPAIKYTLEQALEFIDDDELVEITPESIRIRKKLLTENDRKRAGRTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-06-02" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0S1</accession>
    <name>D0Z0S1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_003135</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301964.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003135"/>
    <dbReference type="EnsemblBacteria" id="EEZ42102">
        <property type="protein sequence ID" value="EEZ42102"/>
        <property type="gene ID" value="VDA_003135"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3852">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Histidine kinase" evidence="4">
        <location>
            <begin position="137"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ42102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="353" mass="39284" checksum="57EF14B8DF2A212B" modified="2010-01-19" version="1">MTAPDSTTIIDNLVTAVLLLDETLTICEVNPASEQLFSLSQRKLVGSKLNELGQHCSLDSEHLIQALEHGQSFSDSEVIWGLCDGKALTLDLDASPIMANGTRYVLLELRAVDQQRRISHEVSQYAQQQAAKELVRGLAHEIKNPLGGLRGAAQLLEKVLPSDQYQEYTQMIIEQADRLRNLVDRLLGPQKPGLRHSQNIHAVLERVRQLLQYEAGESIVIERDYDPSLPDFEMDSEQLEQALLNIVRNALQALASQSQNPAPKIVLKTRTEHQINIKGQHHRTVARIDLIDNGPGIPDQLQDTLFYPMVSGRSDGTGLGLSIARNLVDQHQGKIEVVSWPGHTAFTVYLPIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0Z8</accession>
    <name>D0Z0Z8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Type cbb3 cytochrome oxidase biogenesis protein CcoG involved in Cu oxidation</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_003212</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302178.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003212"/>
    <dbReference type="EnsemblBacteria" id="EEZ42179">
        <property type="protein sequence ID" value="EEZ42179"/>
        <property type="gene ID" value="VDA_003212"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0348">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1230380at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014116">
        <property type="entry name" value="Cyt_c_oxidase_cbb3_FixG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032879">
        <property type="entry name" value="FixG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13746">
        <property type="entry name" value="Fer4_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12801">
        <property type="entry name" value="Fer4_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11614">
        <property type="entry name" value="FixG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02745">
        <property type="entry name" value="ccoG_rdxA_fixG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="139"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="177"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="314"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="237"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ42179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="445" mass="51347" checksum="1C1AE71582631CD5" modified="2010-01-19" version="1">MASSKIYVRAITGYYQKLRQKITWVLMLLFIALPWLNYQQRQAILFDIEHQQFHLFSTTLWPQDFTILALIFIIAAFALFFITTFLGRVWCGYLCPQTVWSALFQWWEEKLEGPANKRRSQDNKRYSSSLWLKKTVKHCIWLLIAFFTAVSFVGYFVPVRQLISQSITFNLSNGPLFWIVFFTLCTYLNAGWLRATVCLHMCPYARFQSAMFDKDTYIVAYHNDRAEPRGPRSRKQDPKQLGLGDCIDCNLCVQVCPTGIDIRDGLQYECINCGACIDACDNTMAKMSYPKRLISYTTEHQLTGKKSNILRPKLLAYGGVLSAMTVAFLFSLNTIKPMEFDVLRDRNQLFRETNLGQIANTYTLKVSNKSQHIAQYQLTVDSQTPLAWQGKRTVILQPQEIANIPITLTVEPKQITQSLWPITFKIATENQQTSTVESRFIAKLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z150</accession>
    <name>D0Z150_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ubiquinone biosynthesis accessory factor UbiK</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ubiK</name>
        <name evidence="2" type="ORF">VDA_003264</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the UbiK family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302327.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003264"/>
    <dbReference type="EnsemblBacteria" id="EEZ42231">
        <property type="protein sequence ID" value="EEZ42231"/>
        <property type="gene ID" value="VDA_003264"/>
    </dbReference>
    <dbReference type="GeneID" id="57340310"/>
    <dbReference type="eggNOG" id="COG2960">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1995361at2"/>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02216">
        <property type="entry name" value="UbiK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007475">
        <property type="entry name" value="UbiK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38040">
        <property type="entry name" value="PTHR38040"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04380">
        <property type="entry name" value="BMFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="59"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="86" mass="9999" checksum="F1A1D05C655D9EF7" modified="2010-01-19" version="1">MFDPKKLEQVAKQIHESMPQPVKDLGNDVEQKVRQVIQSQLGKLDVVNREEFDVQTQVLLRTRQKLTELEQKMAELEAKLNNNKDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z180</accession>
    <name>D0Z180_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_003294</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302417.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003294"/>
    <dbReference type="EnsemblBacteria" id="EEZ42261">
        <property type="protein sequence ID" value="EEZ42261"/>
        <property type="gene ID" value="VDA_003294"/>
    </dbReference>
    <dbReference type="GeneID" id="57340270"/>
    <dbReference type="eggNOG" id="COG1280">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1440181at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001123">
        <property type="entry name" value="LeuE-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30086">
        <property type="entry name" value="PTHR30086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01810">
        <property type="entry name" value="LysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006324">
        <property type="entry name" value="LeuE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="40"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="70"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="116"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="149"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="185"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ42261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="205" mass="21885" checksum="1F9D872143E8A8F8" modified="2010-01-19" version="1">MSIEVWLAYLATAIVFSFAPGSGTVNSISNGMVHGFRKSLASIAGLQLGMSVHILLVGVGLGAIVAQSAALFTAIKWVGAAYLVWLGIQKWREHSAIDISTSNKAVSAQTLFRQAVLVNLTNPKTIVFLVALFPQFLSPTEPQLPQIAILGITTLVVDGCVMLFYVTLAAKLSRYIRSARVMNRLNRVFGSMFIGCGALLASAQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-12-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z181</accession>
    <name>D0Z181_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Non-specific DNA-binding protein Dps/iron-binding ferritin-like antioxidant protein/ferroxidase</fullName>
            <ecNumber evidence="4">1.16.3.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_003295</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the Dps family.</text>
    </comment>
    <dbReference type="EC" id="1.16.3.1" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302421.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003295"/>
    <dbReference type="EnsemblBacteria" id="EEZ42262">
        <property type="protein sequence ID" value="EEZ42262"/>
        <property type="gene ID" value="VDA_003295"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0783">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1742631at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004322">
        <property type="term" value="F:ferroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01043">
        <property type="entry name" value="DPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002177">
        <property type="entry name" value="DPS_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023188">
        <property type="entry name" value="DPS_DNA-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008331">
        <property type="entry name" value="Ferritin_DPS_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42932">
        <property type="entry name" value="PTHR42932"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00210">
        <property type="entry name" value="Ferritin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005900">
        <property type="entry name" value="Dps"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01346">
        <property type="entry name" value="HELNAPAPROT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00818">
        <property type="entry name" value="DPS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00819">
        <property type="entry name" value="DPS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ferritin" evidence="3">
        <location>
            <begin position="21"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ42262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="158" mass="18338" checksum="CAE4D34CC9200117" modified="2010-01-19" version="1">MTQQINLIGLDSDKAKALAVHLNQLLAHYQVLYMNTRGYHWNVKGQEFFELHLKFEEIYTDLQTKIDELAERILTLGFTPDHSFSRYLEQSGIKEYRDITNGKECVKGLVEGFSKLLVKEREILAQAGDADDEGTTALMSDYIREQEKLMWMLNAYLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1B3</accession>
    <name>D0Z1B3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Hypothetical ComF-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_003327</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003327"/>
    <dbReference type="EnsemblBacteria" id="EEZ42294">
        <property type="protein sequence ID" value="EEZ42294"/>
        <property type="gene ID" value="VDA_003327"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1040">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1937725at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ42294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="249" mass="28679" checksum="6E61F2B491251E82" modified="2010-01-19" version="1">MMWHSILSKLNPESILAWHCRLCRLPLSSGQQLWCDNCRRHIEQLHYCQRCGATLTQSASTLTCGRCLVSPPPWHHFYRLGLHQFPLKQVVHPFKFQRQFYLAAPLAQWLAQQIEQPAPVLLPVPLHRYRLWQRGFNQSTLLAWSLAKALNSECLSHGFIRTRHTPPQKKLKRSERQQNLKGAFQLQAKQLPPHIALVDDVVTTGSTLKELISLLPSHIERIDVYALSYTPVTQFQVSPRKSDKTGVKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1G4</accession>
    <name>D0Z1G4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_003378</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302604.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003378"/>
    <dbReference type="EnsemblBacteria" id="EEZ42345">
        <property type="protein sequence ID" value="EEZ42345"/>
        <property type="gene ID" value="VDA_003378"/>
    </dbReference>
    <dbReference type="GeneID" id="57340172"/>
    <dbReference type="eggNOG" id="COG2345">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1288973at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001034">
        <property type="entry name" value="DeoR_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08220">
        <property type="entry name" value="HTH_DeoR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH deoR-type" evidence="3">
        <location>
            <begin position="5"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ42345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="206" mass="23773" checksum="E9654CE3414D2058" modified="2010-01-19" version="1">MKTNDKILHLLKREGATTAKSIAERFELTTMGIRLQLQALEQQGLVEYFDVKVKVGRPQRHWQLSQQGHNQFSDRHDDLLIQTFDAVENLFGHDGLTRVIKEREQQSLLHYQAHIPADATLAEKLKLFSALRDQEGYITELIPQENGFLFVENHCPICQAATRCPNLCQSELSILTQVLGKQYQIERSEHIVAGQRRCAYWIYPMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1J8</accession>
    <name>D0Z1J8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003412</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003412"/>
    <dbReference type="EnsemblBacteria" id="EEZ42379">
        <property type="protein sequence ID" value="EEZ42379"/>
        <property type="gene ID" value="VDA_003412"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="39" mass="4401" checksum="CD7FAB436865C353" modified="2010-01-19" version="1">MVNYTKMKVGMGGKDEEEETTQANHTQCGSRTLWRAIKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1K0</accession>
    <name>D0Z1K0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 10">Phosphoglycolate phosphatase</fullName>
            <shortName evidence="10">PGP</shortName>
            <shortName evidence="10">PGPase</shortName>
            <ecNumber evidence="5 10">3.1.3.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">VDA_003414</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>2-phosphoglycolate + H2O = glycolate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14369"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29805"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58033"/>
            <dbReference type="EC" id="3.1.3.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Organic acid metabolism; glycolate biosynthesis; glycolate from 2-phosphoglycolate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.18" evidence="5 10"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302668.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003414"/>
    <dbReference type="EnsemblBacteria" id="EEZ42381">
        <property type="protein sequence ID" value="EEZ42381"/>
        <property type="gene ID" value="VDA_003414"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0546">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1562270at2"/>
    <dbReference type="UniPathway" id="UPA00865">
        <property type="reaction ID" value="UER00834"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008967">
        <property type="term" value="F:phosphoglycolate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046295">
        <property type="term" value="P:glycolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00495">
        <property type="entry name" value="GPH_hydrolase_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006346">
        <property type="entry name" value="PGPase/MupP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037512">
        <property type="entry name" value="PGPase_prok"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01449">
        <property type="entry name" value="PGP_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7 10 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Nucleophile" evidence="10">
        <location>
            <position position="13"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ42381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="229" mass="25149" checksum="6F62B3E99170DA46" modified="2010-01-19" version="1">MKQLEGIKFIAFDLDGTLLDSVPDLALAADQTMKALGRLSVSLEQVTTWIGNGADILIGRCLSMNSDIDPNLDPELHRQARQLFDQFYHDGGHKLTKLYPDVVATLEKLHQAGMPMAVVTNKPSQFVPGILQEYGIAPFFVDVIGGDTFELKKPDPFALHWLMEKHQLAANELLMVGDSRNDILAAKAATSPSVGLTYGYNYGVPISTSEPTIVLDHFNQLTDVLRLGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1Q2</accession>
    <name>D0Z1Q2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hypothetical glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003466</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303528.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003466"/>
    <dbReference type="EnsemblBacteria" id="EEZ42433">
        <property type="protein sequence ID" value="EEZ42433"/>
        <property type="gene ID" value="VDA_003466"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="635734at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="1">
        <location>
            <begin position="11"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="324" mass="36778" checksum="C44529BCA355FDCB" modified="2010-01-19" version="1">MIYQVIDSRNFGGIESHILQLACLLHRYNYPVTIVFMRHYSPAHPLRQQAESAKIPVLTTAQLPSFYHLKQGDILHGHGYKASLFVRIYGLFSRAKVITTFHAGEIATGKVAFYEWLNRSSAFLSKNIVISQVIGQKISAKYDYWHNFISLPKLPSKLAKPNKIMNVAFVGRLEKVKGFDRFCVIANALPQYQFHVFGDGLLHKLIPEHIHDHGMVSAMDGYWSQLDVLLIPSRAEGLPMAAIEAMANQVIVIATNVGDLAKLLAPEFLVPNSNWQQLSILLNSLNKLSPSEWKKICDDNYYKIQRDYSEQQAIKQLKLTYGFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1S3</accession>
    <name>D0Z1S3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Tyr recombinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_003487</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303581.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003487"/>
    <dbReference type="EnsemblBacteria" id="EEZ42454">
        <property type="protein sequence ID" value="EEZ42454"/>
        <property type="gene ID" value="VDA_003487"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0582">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="215800at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0229">DNA integration</keyword>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyr recombinase" evidence="3">
        <location>
            <begin position="162"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ42454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="498" mass="55998" checksum="A311D141B1C7FF0C" modified="2010-01-19" version="1">MSHNGFEFDYLSDRWTLNRNVTAQVGFLNTFEQPLQDDIRETLVYFAEHHSAKYVQNLINMLKVYLRESGCGDFSEIGFLSFKNKMSKPLQYKVAYVRGFVRQMRFLGLDRHIDDAVFKLTDQWRISGNDKGAAVLTLDPETGPFSDLEFEAIGLHAAHRYAEGKLATEEYACLSMFKASGRRAEQIASIKCKDFSYSAKYTGTLMYVVLIPKAKVRGGKFRSVLKPYALVNSVAQVVEQHIQEQTAKVEDALGRKMTLEEKGELPLFIDVGMIEEMQSINPDALMDYLKSELPHSKTRDLTDNLNGAVKKLEIISERTGEPLKSTSYRFRYTLGTRAAREGAGTLTIATLLDHSDTQNVHVYVANAPEHAVHISKIINQPLARYASVFAGKLVEDEAEANAENAGAARIPCREKECDVGSCGSSSYCQDYAPIACYLCPKFRPWANAPHHLILEWLVEERERLIADTNGDMQIVSINDRAILAVCQVIQLCREHNDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1Y6</accession>
    <name>D0Z1Y6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">GTP cyclohydrolase 1</fullName>
            <ecNumber evidence="6">3.5.4.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">GTP cyclohydrolase I</fullName>
            <shortName evidence="6">GTP-CH-I</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">folE</name>
        <name evidence="8" type="ORF">VDA_001976</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>GTP + H2O = 7,8-dihydroneopterin 3'-triphosphate + formate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17473"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:58462"/>
            <dbReference type="EC" id="3.5.4.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 6">Cofactor biosynthesis; 7,8-dihydroneopterin triphosphate biosynthesis; 7,8-dihydroneopterin triphosphate from GTP: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homopolymer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the GTP cyclohydrolase I family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.16" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299068.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001976"/>
    <dbReference type="EnsemblBacteria" id="EEZ40944">
        <property type="protein sequence ID" value="EEZ40944"/>
        <property type="gene ID" value="VDA_001976"/>
    </dbReference>
    <dbReference type="GeneID" id="57341884"/>
    <dbReference type="eggNOG" id="COG0302">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1632367at2"/>
    <dbReference type="UniPathway" id="UPA00848">
        <property type="reaction ID" value="UER00151"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003934">
        <property type="term" value="F:GTP cyclohydrolase I activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035998">
        <property type="term" value="P:7,8-dihydroneopterin 3'-triphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.286.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00223">
        <property type="entry name" value="FolE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043133">
        <property type="entry name" value="GTP-CH-I_C/QueF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043134">
        <property type="entry name" value="GTP-CH-I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001474">
        <property type="entry name" value="GTP_CycHdrlase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018234">
        <property type="entry name" value="GTP_CycHdrlase_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020602">
        <property type="entry name" value="GTP_CycHdrlase_I_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11109">
        <property type="entry name" value="PTHR11109"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01227">
        <property type="entry name" value="GTP_cyclohydroI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00063">
        <property type="entry name" value="folE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00859">
        <property type="entry name" value="GTP_CYCLOHYDROL_1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00860">
        <property type="entry name" value="GTP_CYCLOHYDROL_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5 6 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 6" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="GTP_cyclohydroI" evidence="7">
        <location>
            <begin position="38"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ40944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="217" mass="24453" checksum="8183D75F0544C923" modified="2010-01-19" version="1">MTTLSESALKVREALAARGLETPMTDLVVERNEKKEKIEHHMREILNLLSLDLTDDSLQETPHRIAKMYVDEIFSGLDYANFPKITVIENKMNCDEMVRVKDITLTSTCEHHLVTIDGKATVAYIPRGKIIGLSKINRIVRFFAQRPQVQERLTQQVLVALQTLLESEDVAVRIDATHYCVKSRGVMDATSETTTTALGGIFKRNPATRAEFLHGVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1Z7</accession>
    <name>D0Z1Z7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative NADH-dependent flavin oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001983</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299089.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001983"/>
    <dbReference type="EnsemblBacteria" id="EEZ40951">
        <property type="protein sequence ID" value="EEZ40951"/>
        <property type="gene ID" value="VDA_001983"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1902">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1033671at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxidored_FMN" evidence="1">
        <location>
            <begin position="4"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="367" mass="41461" checksum="49A1576B995F4CA6" modified="2010-01-19" version="1">MSILFTESRLGNMTLKNRFVRSATWENMATEDGHMTEKLYDIYEELAQGEVGLIVTGYANIVEEEKPNAGMMGMYNDSFIDEYKKLTDLVHRYDSKIVMQLAYGGTKTTYNVGERVIFAPSAVAEKGTNTLGKAMTQDEIDYIVQAFAQAARRAQESGFDGIEIHAAHTYLINQFLSPYYNQRTDQYGGSLENRMRFLVEIIQETRKLVGNDFPILVKLTATEFFEGGQTFEETRIICKKLEQLGVDGIIVSGNIHGKADTMVGEKHDGYTIEAEGYFHQYGQVISQEVSIPVITVGGLSDFSAIEEIANTTNIQYFALSRPLLAEPQLIKRWKDGNIEPVDCERCSKCRTRRGNFCVVYKKRKKVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z238</accession>
    <name>D0Z238_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glycerol-3-phosphate dehydrogenase</fullName>
            <ecNumber evidence="8">1.1.5.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">VDA_001774</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:18977"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.1.5.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5">Polyol metabolism; glycerol degradation via glycerol kinase pathway; glycerone phosphate from sn-glycerol 3-phosphate (anaerobic route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Composed of a catalytic GlpA/B dimer and of membrane bound GlpC.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.5.3" evidence="8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001774"/>
    <dbReference type="EnsemblBacteria" id="EEZ40742">
        <property type="protein sequence ID" value="EEZ40742"/>
        <property type="gene ID" value="VDA_001774"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0578">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00618">
        <property type="reaction ID" value="UER00673"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009331">
        <property type="term" value="C:glycerol-3-phosphate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052591">
        <property type="term" value="F:sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019563">
        <property type="term" value="P:glycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006072">
        <property type="term" value="P:glycerol-3-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007419">
        <property type="entry name" value="BFD-like_2Fe2S-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041854">
        <property type="entry name" value="BFD-like_2Fe2S-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000447">
        <property type="entry name" value="G3P_DH_FAD-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017752">
        <property type="entry name" value="G3P_DH_GlpA_su"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11985">
        <property type="entry name" value="PTHR11985"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04324">
        <property type="entry name" value="Fer2_BFD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01001">
        <property type="entry name" value="FADG3PDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03377">
        <property type="entry name" value="glycerol3P_GlpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAO" evidence="12">
        <location>
            <begin position="3"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="domain" description="Fer2_BFD" evidence="13">
        <location>
            <begin position="408"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00007330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00011331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00013029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF04324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEZ40742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="532" mass="59209" checksum="147F17EB5D21AE06" modified="2010-01-19" version="1">MRDCALRGINCILIEKDDLASGTTGRNHGLLHSGARYAVTDSESARECIVENRILKKIARHCVEDTQGLFISLPDDDLDFQKQFITSCQQADIDVEQLTPQEALRLEPNCNPNLIGAVKVPDGTLDPFRLAASNVIDAVEHGARLFNHTMVTSLIRDGHTVKGVNCLNLKTGEHFEIRAKQVVNAAGIWGQQICEYADLNIKMFPAKGSLLILDYRINNLVINRCRKPSDADILVPGDTISLIGTTSERIDYDKIDDLHVTSKEIDILLEEGTKLAPIMANTRVLRAYAGVRPLVAVDGDTSGRNISRGIVLLDHHERDGMDGFITITGGKLMTYRMMAEWTTDLVAKKLGNTMPCITHEKPLPGSEQASDNIKHTASLAKPVYQSAYYRHGERAAKFLKEEKKSQAVICECEMVTSGEVEYAIKELDVHNLVDLRRRTRVGMGPCQGELCSYRAAGLFAEYGDATGTQASQLLQHFLEERWKGIKPVFWGDALREGEFTYWIYEGLFGVSDIPQTDEQNPQQQQYTDEAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z266</accession>
    <name>D0Z266_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001913</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40881">
        <property type="protein sequence ID" value="EEZ40881"/>
        <property type="gene ID" value="VDA_001913"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="58" mass="6834" checksum="84225394DC6077BC" modified="2010-01-19" version="1">MKEVKSCIVEGQKVVWLIDVKERFSFAFTQIEQSLKQLQIGYEKVLLGKIYHCTSEHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z270</accession>
    <name>D0Z270_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001916</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298931.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40884">
        <property type="protein sequence ID" value="EEZ40884"/>
        <property type="gene ID" value="VDA_001916"/>
    </dbReference>
    <dbReference type="GeneID" id="57341958"/>
    <dbReference type="eggNOG" id="ENOG5031N5U">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1814448at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="121" mass="13445" checksum="B00E89EE821FBE9F" modified="2010-01-19" version="1">MQKIKITPNPHVAAIFQGWSEDWSKEAKAEQKDSANQFHTVYKIAGELFTKGGELDANVVSALYNDCKQKVTMSKAMVDKVKSALANDEEKAELLIKKINTTAQDAAYIVKELGQQMLEQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z275</accession>
    <name>D0Z275_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Hypothetical ribonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001920</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the RNase T2 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298938.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001920"/>
    <dbReference type="EnsemblBacteria" id="EEZ40888">
        <property type="protein sequence ID" value="EEZ40888"/>
        <property type="gene ID" value="VDA_001920"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3719">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1693572at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033897">
        <property type="term" value="F:ribonuclease T2 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.730.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001568">
        <property type="entry name" value="RNase_T2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036430">
        <property type="entry name" value="RNase_T2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018188">
        <property type="entry name" value="RNase_T2_His_AS_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033130">
        <property type="entry name" value="RNase_T2_His_AS_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11240">
        <property type="entry name" value="PTHR11240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00445">
        <property type="entry name" value="Ribonuclease_T2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55895">
        <property type="entry name" value="SSF55895"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00530">
        <property type="entry name" value="RNASE_T2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00531">
        <property type="entry name" value="RNASE_T2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018782" evidence="4">
        <location>
            <begin position="26"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="336" mass="37603" checksum="3285F684EE6B94F5" modified="2010-01-19" version="1">MITNKKITRFSLLSSLLLTPLLSHASIPTHGDFTAKQACDAFQSFRKQSNPQSVQLSVGQRYEITAINKEAFDWVQIKVPGSSPLTRWVKSSCGESNFLGQSKPTTKPSTPNNNKGNGSCSTAGNFDSYVLALTWQPGFCEHFSYKGKKPECDAINSGKLASTNLTLHGLWPNKKSCGTNYGYCDDSNKLDLSRSTINKIAPWMPNFYYQTKFGEYEWRKHGTCQTQSADQYFMTAVDLVKQVDASEIGQYIKENIGRNIKADQFKQVLVDRMGKEAVNRIRLSCTKGKYLNEVRINLPEPLDMTASLVSQMEKAPRTKSFYGNCKKIIHIEAAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2D1</accession>
    <name>D0Z2D1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000582</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304769.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000582"/>
    <dbReference type="EnsemblBacteria" id="EEZ39562">
        <property type="protein sequence ID" value="EEZ39562"/>
        <property type="gene ID" value="VDA_000582"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502ZEUJ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1534908at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="224" mass="25575" checksum="BEC5E0022523CF06" modified="2010-01-19" version="1">MEKLDLDEAQQIERLYATSPEYEWELIVNPDSSRTKGTIISFIIFVLVGVLFLLIGFSWLALVPIVVGAFMSPWYRYLLNADKRYYFAINQYGMYSRNEQIIPEIAYTIVRYSAWVGCGICLFAAILVGPIAFVGAGGAALLSFQMTNFRSVARKSQCLFDNAAILKNYCENDYLLRTENSMIPLIIPECKLPRVIEVIKQYNDSFEEVFVDSKSNLIILEIVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2E7</accession>
    <name>D0Z2E7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000598</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39578">
        <property type="protein sequence ID" value="EEZ39578"/>
        <property type="gene ID" value="VDA_000598"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG50330T2">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="103" mass="10352" checksum="E2A23137A2FC4528" modified="2010-01-19" version="1">MEGVNQEQYQQDFTYCQGYAEQVSKGEAARVAAINTAVPTAIMGAIAGGIGNGVQGALGGAVAGGTMGAGVGAFGGATSTTETQALVLRQCLKQKGYKVYDLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2G3</accession>
    <name>D0Z2G3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000614</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304876.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39594">
        <property type="protein sequence ID" value="EEZ39594"/>
        <property type="gene ID" value="VDA_000614"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031NM3">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2059026at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="63" mass="7242" checksum="C06499A2DB20A8E2" modified="2010-01-19" version="1">MAQVMNFETVTSDDVLNQKTYAVSFKGLIAHFMDILFVRSKSVKEYNVSDLSVHLQKDIGLYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2S7</accession>
    <name>D0Z2S7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phospho-2-dehydro-3-deoxyheptonate aldolase</fullName>
            <ecNumber evidence="5">2.5.1.54</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_000728</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 5">Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14717"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16897"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="2.5.1.54"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 5">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 1/7.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the class-I DAHP synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.54" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000728"/>
    <dbReference type="EnsemblBacteria" id="EEZ39708">
        <property type="protein sequence ID" value="EEZ39708"/>
        <property type="gene ID" value="VDA_000728"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0722">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00084"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003849">
        <property type="term" value="F:3-deoxy-7-phosphoheptulonate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006218">
        <property type="entry name" value="DAHP1/KDSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006219">
        <property type="entry name" value="DHAP_synth_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21225">
        <property type="entry name" value="PTHR21225"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00793">
        <property type="entry name" value="DAHP_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001361">
        <property type="entry name" value="DAHP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00034">
        <property type="entry name" value="aroFGH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAHP_synth_1" evidence="6">
        <location>
            <begin position="59"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR001361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="370" mass="40985" checksum="028EEB595991C96A" modified="2010-01-19" version="1">MYQRNVMTDTTLIIEQDRTMYKTDDVRISEIKQLLPPVAILERFPATDHAAKTVYDSRQAIHNILNDQDDRLLVVVGPCSIHDPDAALEYGKKLLALREQLKGELEIVMRVYFEKPRTTVGWKGLINDPYMDNSFQLNDGLRIGRKLLLDLTDMGMPTAGEFLDMITPQYMGDLISWGAIGARTTESQVHRELASGLSCPVGFKNGTDGNIKIATDAIGSASAPHHFLSVTKYGHSAIVSTAGNEDCHIILRGGKDPNYSAEHVDAITAQLAKAGHRQKVMIDFSHANSLKQYQRQMLVAEDVGSQIAQGNNAIFGVMIESHLVEGRQDIIDGVEPTYGQSITDACIGWDDTEKALTQLAHDVKKRRVLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2V7</accession>
    <name>D0Z2V7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Formate dehydrogenase</fullName>
            <ecNumber evidence="6">1.17.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">VDA_000758</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>formate + NAD(+) = CO2 + NADH</text>
            <dbReference type="Rhea" id="RHEA:15985"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.17.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
            <dbReference type="ChEBI" id="CHEBI:60539"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.17.1.9" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000758"/>
    <dbReference type="EnsemblBacteria" id="EEZ39738">
        <property type="protein sequence ID" value="EEZ39738"/>
        <property type="gene ID" value="VDA_000758"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0493">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3383">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009326">
        <property type="term" value="C:formate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008863">
        <property type="term" value="F:formate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043546">
        <property type="term" value="F:molybdopterin cofactor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015942">
        <property type="term" value="P:formate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02790">
        <property type="entry name" value="MopB_CT_Formate-Dh_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02753">
        <property type="entry name" value="MopB_Formate-Dh-H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041925">
        <property type="entry name" value="CT_Formate-Dh_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028261">
        <property type="entry name" value="DPD_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041924">
        <property type="entry name" value="Formate_Dh-H_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006478">
        <property type="entry name" value="Formate_DH_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006657">
        <property type="entry name" value="MoPterin_dinucl-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006656">
        <property type="entry name" value="Mopterin_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006963">
        <property type="entry name" value="Mopterin_OxRdtase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006655">
        <property type="entry name" value="Mopterin_OxRdtase_prok_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14691">
        <property type="entry name" value="Fer4_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12838">
        <property type="entry name" value="Fer4_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04879">
        <property type="entry name" value="Molybdop_Fe4S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00384">
        <property type="entry name" value="Molybdopterin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01568">
        <property type="entry name" value="Molydop_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00926">
        <property type="entry name" value="Molybdop_Fe4S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="SSF50692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01591">
        <property type="entry name" value="Fdh-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51669">
        <property type="entry name" value="4FE4S_MOW_BIS_MGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00490">
        <property type="entry name" value="MOLYBDOPTERIN_PROK_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="15" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12 15" id="KW-0408">Iron</keyword>
    <keyword evidence="13 15" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="19" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-0574">Periplasm</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0677">Repeat</keyword>
    <keyword evidence="14" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="16">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="17">
        <location>
            <begin position="602"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="17">
        <location>
            <begin position="651"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S Mo/W bis-MGD-type" evidence="18">
        <location>
            <begin position="689"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="696"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="699"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="703"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="733"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EEZ39738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="1376" mass="151192" checksum="EE1AD189BFCBF871" modified="2010-01-19" version="1">MFAIDPDQNLLEAAKQCQVDIPSLCGKNTKGEKVACNLCVVEIDGQGVQRACETKPAEGMSVTTQSEELSSRRQTALNKILSDHYADCEAPCQTACPAGVDIQSYLYHISQNDHQKAVEVIKRTLPMPLSIGRVCPAFCEAECRRGLVDEPIAIRQLKRHAADIDLKAQEAYVPEKKPAKGKSIAVVGSGPGGLTCGYYLSNEGYNVTVYEAMPETGGWLRYGIPEYRLPKSILDKEVELMCRNGMEIYTNKKLGEDFTLSDLSHDFDAVCLAVGASKAVEMHYTGSDLDGCYLGVDYLKDYVTEHKLVTGKKVAVIGGGNTAIDCARTAVRDGADTTLIYRRTRDEMPAEDYEIAEAEHEGVKFHFLTNPAENIADANGRVCQVKLEKMALGEPDASGRRSPKATGEFFIEEFDTVIAAVSQKADLSFLDNETIELPLTRWNTSDAHPETMHSGVENIFSIGDFRRGPATAIEAVADGRRAAQAIDRFFSGSMEQIPAKEFNSQKETKLKLVAPEQFAAIPKVMRAVMPELSSEQRALNFGEVELGFDNEAAITEAARCLECGCQANKDCKLRDYATEYKAAETDLENEAKQKFCVDDSSEFIVFDANRCISCGQCVQACNEKAVHGVLSFMKNADGTPAQRPECRPGFDGVNMGDSKCVQCGACVQACPTGALVDKRDKAQGRIELLTPVETICTYCGIGCRLTMFVDKAKNKIRYVQGSEKSPVNQGMLCVKGRFGFDFINSQERLQTPLIRKEGQLVPATWDEAISLIAEKFTAIKNEKGGDALAGFSSAKTTNEDNFVFQKFVRCEFETNNVDHCARLCHASTVTGLEASLGSGAMTNDIPSIKHSDLIFIIGSDTSSAHPIIGSHIKQAVRHHGARLIVADPKKVDIVAHAELYVAQRPGTDVMLLNGIMQQIIKNNWHDQAYIDERVEGFNALKAEVMQEAYSLEKVELVTGVKASDVLEMARLIGTAERTAIYYSMGITQHTTGHDNVRSIANLQMLCGNIGIEGAGINPLRGQSNVQGACDMGALPWDFPGYQKVEVPENHQKFAKAWNKPNLPAKKGLTLTEIIDAACHDQVKGLYVMGENPVLSDPNQAHVIEGLEKLDFLVVQDIFLTETAEYADVVLPSCSFAEKDGHFTNTERRVQRIQAAVNPPGEAKQDWQILQMVSQAMGGQWHYDSVQEITEEITQLTPQYAGISWDAVGYEGIQWPCNVNKPQGTRIMHEERFVRGKGEMAAVPFRYAAELPDEEFPLVLTTGRLLEQFHTGTMTRKTKGLDNLAGPRAMISVTDAERLGIHNGEMIRVATRRGAIETPAFVTKRMQDGVVFVPFHFAESPANRLTITATDPHAKIPEFKVAAVKIEKIEAKEVELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2X0</accession>
    <name>D0Z2X0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Iron-sulfur cluster assembly protein SufB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000771</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0051 (ycf24) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305298.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000771"/>
    <dbReference type="EnsemblBacteria" id="EEZ39751">
        <property type="protein sequence ID" value="EEZ39751"/>
        <property type="gene ID" value="VDA_000771"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0719">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="635721at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010231">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000825">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037284">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045595">
        <property type="entry name" value="SufBD_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01458">
        <property type="entry name" value="SUFBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19295">
        <property type="entry name" value="SufBD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101960">
        <property type="entry name" value="SSF101960"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01980">
        <property type="entry name" value="sufB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SufBD_N" evidence="2">
        <location>
            <begin position="150"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="492" mass="54699" checksum="418948956C5B267A" modified="2010-01-19" version="1">MSIPELQPDIDHVLNHKRYKEGFYTDVVSDTFSKGINEEVIRAISAKRNEPDWMLEFRLNAFNYWLTMKEPHWLKAEYPKLDYQDYSYYSAPSCARCDNIDSSNTDQESANSEFLTQEVEEAFELLGVPVREGADIAVDAIFDSVSVATTYHEELKQLGIIFCSFSEAIQQYPELVKKYLGTVVPAKDNFFAALNAAVASDGTFIYIPPGVRCPRELSTYFRINQAKTGQFERTILVADKGAYVSYIEGCSAPVRDSYQLHAAVVEVIIHQDAEVKYSTVQNWFAGEEGQDGGILNFVTKRALCEGRNSKMSWTQSETGSAITWKYPSVILQGDNSVGEFFSVALTNGNQKADTGTKMIHIGKNTKSTIISKGISAGQSENSYRGLVKILPSAQGARNYTQCDSMLIGNKCGAHTFPTVDVRNPSAQIEHEATTSRIGEDQLFYCVQRGISEDDAISMIVNGFCKDVFSELPLEFAVDAQKLLSISLEHSVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z316</accession>
    <name>D0Z316_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative hemagglutinin/hemolysin-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000817</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305428.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000817"/>
    <dbReference type="EnsemblBacteria" id="EEZ39797">
        <property type="protein sequence ID" value="EEZ39797"/>
        <property type="gene ID" value="VDA_000817"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2911">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2931">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018511">
        <property type="entry name" value="Hemolysin-typ_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001343">
        <property type="entry name" value="Hemolysn_Ca-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00353">
        <property type="entry name" value="HemolysinCabind"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00739">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51120">
        <property type="entry name" value="SSF51120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00330">
        <property type="entry name" value="HEMOLYSIN_CALCIUM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="3">
        <location>
            <begin position="3543"/>
            <end position="3729"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="3986" mass="412286" checksum="58015DCE1D637585" modified="2010-01-19" version="1">MNIIDLRDDLVVESVQGSVYTIDNKGNLVQLYAGSHLNKGDKVILQNDASFDALVHNQTVTFDNSADNMTVEDLKNLLNQQYAATVHQNYINQSQPDDDLASSLLVKQSHSVDHQISNNVTLDTIHRMIEDGQDPTLAQPKPAAGNELSSSAPGSVYIDYDNDQMLAEAGHDTAYKPTNNQERKDYIGGDESLFLPPLHAGVQILSIAEDNVINESEAHSKVSITGTVSQDVKVGDIVELSLDKQPIGHATVTLVDGELVWTTSVDGSTLVNANLDLVTATVTTHDSHGRTVSATDDHTYSIDTDIAAKITITSIATDDVINADEAYSKVPVTGTVGADVKAGDTVIVMVDGHKVGETQVVEQDGKLTWTAQVDGSVLEHASADSVKATVTTTDAAGNSATATDDHTYSIDTDIAAKITITSIATDDVINADEAHSKVPVTGTVGADVKAGDTVIVMVDGHKVGETQVVEQDGKLTWTAQVDGSVLEHASADSVKATVTITDAAGNRATATDDHLYSIDTDIAAKITITSIATDDVINADEAHSKVPVTGTVGADAKAGDTVMVMVDGHKVGETQVVEQDGKLTWTAQVDGSVLEHASADSVKATVTTTDAAGNRATATDDHTYSIDTDIAAKITITSIATDDVINADEAQSKVPVTGTVGADVKAGDTVIVMVDGHKVGETQVVEQDGKLTWTAQVDGSVLEHASADSVKATVTTTDAAGNSATATDDHLYSIDTDIAAKITITSIATDDVINADEAHSKVPVTGTVGADVKAGDTVIVMVDGHKVGETQVVEQDGKLTWTAQVDGSVLEHASTDSVKATVTTTDAAGNRATATDDHTYSIDTDIAAKITITSIATDDVINADEAQSKVPVTGTVGADVKAGDTVIVMVDGHKVGETQVVEQDGKLTWTAQVDGSVLEHASADSVKATVTTTDAAGNSATATDDHLYSIDTDIAAKITITSIATDDVINADEAHSKVPVTGTVGADVKAGDTVIVMVDGHKVGETQVVEQDGKLTWTAQVDGSVLEHASTDSVKATVTTTDAAGNRATATDDHLYNIDTDIAAKITITSIATDDVINADEAHSKVPVTGTVGADVKAGDTVTVIVDGKTVGTTTVENHDGKLTWTAQVDGSVLEHASADSVKATVTTTDAAGNRATATDDHTYSIDTDIAAKITISSIATDDVVNADEAHSKVPVTGTVGADVKAGDTVTVIVDGKTVGTTTVENHDGKLTWTAQVDGSVLEHASTDSVKATVTTTDAAGNRATATDDHLYSIDTDITAKITITSIATDDVINADEAHSKVPVTGTVGADVKAGDTVTVIVDGKTVGTTTVENHDGKLTWTAQVDGSVLEHASADSVKATVTTTDAAGNRATATDDHTYSIDTDIAAKITITSIATDDVVNADEAHSKVPVTGTVGADVKAGDTVTVIVDGKTVGTTTVENRDGKLTWTAQVDGSVLEHASADSVKATVTTTDAAGNRATATDDHLYSIDTDIAAKITITSIATDDVINADEAHSKVPVTGTVGADVKAGDTVTVIVDGKTVGTTTVENHDGKLTWTAQVDGSVLEHASTDSVKATVTTTDAAGNRATATDDHLYSIDTDIAAKITITSIATDDVINADEAHSKVPVTGTVGADVKADDTVTVIVDGKTVGTTTVENHDGKLTWTAQVDGSVLEHASADSVKATVTTTDAAGNRATATDDHLYSIDTDIAAKITITSIATDDVINADEAHSKVPVTGTVGADVKAGDTVTVIVDGKTVGTTTVENHDGKLTWTAQVDGSVLEHASADSVKATVTTTDAAGNRATATDDHLYNIDTDIAAKITITSIATDDVVNADEAHSKVPVTGTVGADVKAGDTVIVMVDGHKVGETQVVEQDGKLTWTAQVDGSVLEHASADSVKATVTTTDAAGNSATATDDHTYSIDTDIAAKITITSIATDDVVNADEAHSKVPVTGTVGADVKAGDTVTVIVDGKTVGTTTVENHDGKLTWTAQVDGSVLEHASTDSVKATVTTTDAAGNSATATDDHTYSIDTDIAAKITITSIATDDVVNADEAHSKVPVTGTVGADVKAGDTVTVIVDGKTVGTATVENHDGKLTWTAQVDGSVLEHASADSVKATVTTTDAAGNRAIATDDHTYSIDTDIAAKITISSIATDDVVNADEAHSKVPVTGTVGADVKAGDTVTVIVDGKTVGTTTVENHDGKLTWTAQVDGSVLEHASTDSVKATVTTTDAAGNSATATDDHTYSIDTDIAAKITITSIATDDVVNADEAHSKVPVTGTVGADVKAGDTVTVIVDGKTVGTTTVENHDGKLTWTAQVDGSVLEHASADSVKATVTTTDAAGNRAIATDDHTYSIDTDIAAKITISSIATDDVVNADEAHSKVPVTGTVGADVKAGDTVIVMVDGHKVGETQVEEQDGKLTWTAQVDGSVLEHASTDSVKATVTTTDAAGNRATATDDHTYSIDTDIAAKITITSIATDDVINADEAHSKVPVTGTVGADVKAGDTVIVMVDGHKVGETQVEEQDGKLTWTAQVDGSVLEHASTDSVKATVTTTDAAGNRATATDDHTYSIDTDIVAKITITSIATDDVINADEAHSKVPVTGTVGADVKAGDTVIVMVDGHKVGETQVVEQDGKLTWTAQVDGSVLEHASTDSVKATVTTTDAAGNRATATDDHLYNIDTDIAAKITITSIATDDVVNADEAHSKVPVTGTVGADVKVGDTVTVIVDGKTVGTTTVENHDGKLTWTAQVDGSVLEHASTDSVKTTVTTTDAAGNSATATDDHTYSIDTDIAAKITITSIATDDVINADEAHSKVPVTGTVGADVKAGDTVTVIVDGKTVGTTTVENHDGKLTWTAQVDGSVLEHASADSVKATVTTTDAAGNSATATDDHTYSIDTDIAAKITITSIATDDVINADEAHSKVPVTGTVGADVKAGDTVIVMVDGHKVGETQVVEQDGKLTWTAQVDGSVLEHASADSVKATVTTTDAAGNRATATDDHLYSIDTDIAAKITITSIATDDVVNADEAHSKVPVTGTVGADVKAGDTVTVIVDGKAVGTTTVENHDGKLTWTAQVDGSVLEHASADSVKATVTTTDAAGNRAIATDDHTYSIDTDIAASITITSIATDDNVTGPDSEHSQTIIGTVGGDVQEGDHVIVSLDGKVLGTATVQADKSWSLNVDGKVLLDAGSDSVTAMVDIRDAAGNQAHATATHDYTVDVSASIDIDPITGDNIITQKEGHEKVLDVTGKVGGQAREGDEVTVTIGNNKYITHVQKDLTWSIAVAGMDILHANQAIASVTTSYSSHNVTVDADEPYKVDIGALVTIDSIAEDNIVTQAEGKSSVVINGSVGGDVKDGDIVTLTIDGQQFTGEAKDGRYQITVEGSALLKDSDRIVEASVTTTDGAHHSASDTAEKSYQIDGVVIQADNGDNTIVGTVGSDLLIGDLDPAKIVDVPTNVNFVIDTSGSMYYGRLLNLDSIHMNSAEKYKVFVNYGATLTAADGTQLYNGSSQSGWVTVTYDQMKAGLQYDGYRAEDPIYIKSSIGEDQTYKLTDFPSVFDMTKQAYQVLVDEILTNTNDKSSLNFNVVTFNSTVGGDSSFHYDAESNSFVNSRGTDIHNYLNSLIAGGGTEFEAPLKTISDHIVTDGNTRNVVYFLTDGKDNTGFSNSANNSDYAALKHAEVISIAVGPSGDADQVNQIAQLGEGYNNNNDSEPSYSKVITNTNELTDIFKDIGQHFIPGSDTITGSDDNDVLVGDALNIHWMYDEGLLHGQYHEPVKGKVDTYPATIIKQYLADEAHNGDTNKVLTSDINHFIADHLDKFGNNEYGGNDHISGGKGNDILIGDGGNDTLDGGLGDDLLDGGLGNDFLTGGAGNDTFIWSDRSLVAKDSANNNPIDHIKDFAIGEDKIDLTDILDKSDNTTIDDLLKHVSAEIKDVGKDDKADVVLTVHNSDSSKQATIVLDDFASHSDLTGITSSNEIVQHLFNDHVFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z320</accession>
    <name>D0Z320_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Molybdenum ABC transporter, periplasmic molybdenum-binding protein ModA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_000821</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial solute-binding protein ModA family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000821"/>
    <dbReference type="EnsemblBacteria" id="EEZ39801">
        <property type="protein sequence ID" value="EEZ39801"/>
        <property type="gene ID" value="VDA_000821"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0725">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015689">
        <property type="term" value="P:molybdate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005950">
        <property type="entry name" value="ModA"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004846">
        <property type="entry name" value="ModA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01256">
        <property type="entry name" value="modA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018808" evidence="4">
        <location>
            <begin position="23"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>molybdate</name>
            <dbReference type="ChEBI" id="CHEBI:36264"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>molybdate</name>
            <dbReference type="ChEBI" id="CHEBI:36264"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>molybdate</name>
            <dbReference type="ChEBI" id="CHEBI:36264"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>molybdate</name>
            <dbReference type="ChEBI" id="CHEBI:36264"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>molybdate</name>
            <dbReference type="ChEBI" id="CHEBI:36264"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR004846-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="255" mass="27705" checksum="304175F0BAD83359" modified="2010-01-19" version="1">MSVKTWAYSSLLLALFSQGVMAKDVTVFAAASLTNALNEISADYKKESGMNTVMSYASSSTLARQIAQGAPADIYLSANEKWMDYVAEQGVIDKNSRIDLLKNALVLVAPSNYPENKITITSSFDLTKALDGTRLAVGDPAHVPAGRYAKQSLENLGLWKQAEPLLARANNVRGALALVERGEAKLGIVYKTDADITNKVKVVADFPAASHKPITYPIAIVKGQEDNKDVVSFYDYLRGKQAKSVFTKYGFTIVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-06-02" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z328</accession>
    <name>D0Z328_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Tetrathionate reductase two-component response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_000829</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305464.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000829"/>
    <dbReference type="EnsemblBacteria" id="EEZ39809">
        <property type="protein sequence ID" value="EEZ39809"/>
        <property type="gene ID" value="VDA_000829"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4566">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="930905at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="6"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="135"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="216" mass="24256" checksum="C093F0C847091962" modified="2010-01-19" version="1">MLTKTHLFLVDDDDAVLDALEFVLQGEGYEPHCFLSADLFWQFIQQQGTMITGCLVLDSRMPGMSGQELQIALNQLHSSLGIVFLTGHGDIPMAVDALKSGAVDFLLKPIHIDSLLKAIKNALEYSSRQIIRQLSIEKYKQLTQRERDMLALFAKGNNNIDVSNELHISPRTVEVHKSNLLRHLGVTTLAEMITIYTHVESILDTIPPPPTRIKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z339</accession>
    <name>D0Z339_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glutathione S-transferase</fullName>
            <ecNumber evidence="3">2.5.1.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000840</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.5.1.18" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305496.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000840"/>
    <dbReference type="EnsemblBacteria" id="EEZ39820">
        <property type="protein sequence ID" value="EEZ39820"/>
        <property type="gene ID" value="VDA_000840"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0625">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1560019at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13417">
        <property type="entry name" value="GST_N_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="SSF47616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="2">
        <location>
            <begin position="91"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="222" mass="25608" checksum="2B949C5CF9A69522" modified="2010-01-19" version="1">MSDLTVYTLGSPNGIKIPVALEEMGVMYDLHTIDITKGEQFSAAFSKINPRHKIPVLADKSKDSEHPQIIGESCAILLYLAEKFNKLISNDPLHRAQTIEWLFYQASTEGTVFGAYGHFSTYAKDKVKDPYPKERYLNESIKVLDYIESELTGKRYLVADEYSIADIAMFPWIIWIRNFYHIDSVIDMSKYPNILNWVDRCCQRSKTKIGLETYNYLDIKNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z340</accession>
    <name>D0Z340_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000841</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39821">
        <property type="protein sequence ID" value="EEZ39821"/>
        <property type="gene ID" value="VDA_000841"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="49" mass="5793" checksum="69F46F121D5BB1F1" modified="2010-01-19" version="1">MHCFVVNVLTRELELTEHLDFRWLNKDQLWDLDWAAADVAAVEMLSVTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z346</accession>
    <name>D0Z346_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000847</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305516.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000847"/>
    <dbReference type="EnsemblBacteria" id="EEZ39827">
        <property type="protein sequence ID" value="EEZ39827"/>
        <property type="gene ID" value="VDA_000847"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG50323BS">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1206013at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="259" mass="29995" checksum="BB3A7395AE1BB372" modified="2010-01-19" version="1">MKINSYLKKIEQGQPINLEHFQRCLPFSDNNAWRKIYHFVRVRDGYLLTIDDIEAHNELYVDKPSNRVSASKLGRSHDFQTNFSHLLVLNRINDSQIPFVVVCDINGFKTEGKLVGKRAILIENIENFYRYHEFIEALGHSGLVDDSDVIFGSGNQICHHLNISFLSNYEEIYCAQDVELGGLTTFKTLKNVLPQCKWLAPIDWESFKGRFKLKPKNSSHLAKAIKLARELDLNTEADLMNQTRHFMEQEAFLSVFKQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z352</accession>
    <name>D0Z352_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">L-lactate dehydrogenase</fullName>
            <ecNumber evidence="9">1.1.2.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_000853</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.2.3" evidence="9"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305533.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000853"/>
    <dbReference type="EnsemblBacteria" id="EEZ39833">
        <property type="protein sequence ID" value="EEZ39833"/>
        <property type="gene ID" value="VDA_000853"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1186741at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004460">
        <property type="term" value="F:L-lactate dehydrogenase (cytochrome) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02809">
        <property type="entry name" value="alpha_hydroxyacid_oxid_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012133">
        <property type="entry name" value="Alpha-hydoxy_acid_DH_FMN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000262">
        <property type="entry name" value="FMN-dep_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037396">
        <property type="entry name" value="FMN_HAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008259">
        <property type="entry name" value="FMN_hydac_DH_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01070">
        <property type="entry name" value="FMN_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000138">
        <property type="entry name" value="Al-hdrx_acd_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00557">
        <property type="entry name" value="FMN_HYDROXY_ACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51349">
        <property type="entry name" value="FMN_HYDROXY_ACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 7" id="KW-0288">FMN</keyword>
    <keyword evidence="4 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FMN hydroxy acid dehydrogenase" evidence="8">
        <location>
            <begin position="4"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="281"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="83"/>
            <end position="85"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="257"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="279"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="281"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="284"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="312"/>
            <end position="316"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="335"/>
            <end position="336"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000138-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000138-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ39833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="387" mass="43216" checksum="AF7DE6CC3BA9B39A" modified="2010-01-19" version="1">MKDYFNTNYPSIDLLRKKAKCRLPKFAFEYVDGGCNNEIGLKRNTDDIRKLELIPYYLRDYQEISLKTKLFGETYDAPFGVSPIGLQGLIWPQAPEILAKAAFDHNVPFILSTVSTAPIETIAEITEGKMWFQLYHPADDAITDDLLARCKAAGVKTLVLLSDVPTFAYRPKEIKNGLAMPPKMTIPNILQIMASPEWALETLIKGKPEFRTLTKYMPGSMNMHHLALFMDKTFNGRLSEEKVQKLRDKWDGNLVLKGLSTVEDAEKAIHLGLDGIIVSNHGGRQLDAGPSTINKGIEILNACKGKTTIMMDSGIREGSDIACTMAAGMDFTFLGRSFMYTVGALGHNGGNHAMNMLKKQLQQVMEQVCCEKPQDLPNHLAEIKNLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3E5</accession>
    <name>D0Z3E5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">BatD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000946</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305801.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000946"/>
    <dbReference type="EnsemblBacteria" id="EEZ39926">
        <property type="protein sequence ID" value="EEZ39926"/>
        <property type="gene ID" value="VDA_000946"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="997498at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025738">
        <property type="entry name" value="BatD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40940">
        <property type="entry name" value="PTHR40940"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13584">
        <property type="entry name" value="BatD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003020037" evidence="2">
        <location>
            <begin position="35"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="436"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="569" mass="62524" checksum="73EA882A2CD2E976" modified="2010-01-19" version="1">MKKLLNNKKNRQSKWVSLFLIALLTILSPAIAFAAQVEATVSKNIVGLNDVFQLTVKIDDSVNANALDLSPLDADFNYGTPSVSNSTSMINGAISRSTEWNVALAAKKMGKIVIPSFRIGATESQPITITVEKNRNASATKTTQDQQAVQLLTEVDKSSLYQGETFSYRVELRIGAQMSQASLTAPYGDGLDVVQQGDDRQTETVVNGRRYIVVTRYYQITAEKPGKITLNGAKFSGNIVKGNRGGFGFSPSVNIPVKRTAENIALEIKAKPESYTGLWIPTTDLKLEQQWQPQNSTVKVGEPLTRLITLKIKNTSQSNMPNISLEYPSSVRSYNEKPEYSNQNGYTVMTVKQVIIPRKEGKLSLPGLSVNWFNTVTGKEQTSSIDGMKLTVMQEEANTSSALNNQEDKIANITDTNVAPSTSSSVTKNDSAYASIWPWLTALMTILWLGTTIALLKAKRSKQTRSAVINSEAVTVSTLEGLQQAAERNEPIKAQTYFRQWKNENLQLVGSSEAQKVAHEIEIMMNAAYSKQATTWKNDALLQAIKALPTASTKKSQSRSHLAELDPNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3M0</accession>
    <name>D0Z3M0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001021</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306003.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001021"/>
    <dbReference type="EnsemblBacteria" id="EEZ40001">
        <property type="protein sequence ID" value="EEZ40001"/>
        <property type="gene ID" value="VDA_001021"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="694191at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="58"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="176"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="348" mass="39951" checksum="5CDB0AF784B5184D" modified="2010-01-19" version="1">MANIVLVCDIFLKQGSSFFDFLYHLPTHSPHQYILLVRGIDKELSSCLTSLGYEVKIFHSSIDLAKYFLRYQPNLIHFHFYGIGHRHILLAKCLAKKVILTCHNSLLKKPKINVYLRVKQSLLALPLSRVIAVSSFTSSWLCSLLPPIKVVHIDNGVDLTRFRPIPQIEVTQYLECCYIGSLSNEKGVNKLISLFSLPEIARFARLHLVGEGELQKVIHRLPEQTDNIISYGYLNDVTVVLKKVHLVLVPSDWYEAFGYSAVEAMATQRPIIAQPVGALKDLFSNDLHSWHADYNNMISVQKLLERIHRSPLLLKQTGEQAQAWVRQKYDIHNQIKKTHRQYCQLLNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3P7</accession>
    <name>D0Z3P7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001048</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001048"/>
    <dbReference type="EnsemblBacteria" id="EEZ40028">
        <property type="protein sequence ID" value="EEZ40028"/>
        <property type="gene ID" value="VDA_001048"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039536">
        <property type="entry name" value="TetR_C_Proteobacteria"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14246">
        <property type="entry name" value="TetR_C_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="9"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="203" mass="23338" checksum="682FC0287C0DF336" modified="2010-01-19" version="1">MKTKMTRSEQKHLAIIDAAKEEFIQHGFLAANMDRISAAAEVSKRTLYRHFESKEVLFESVLTIIQDEVNQAIQYPYIEGKTLKEQLTEITYKEVDILYNTYGIPLSKTIVMEFMRQPEMAHNLVKTIYSNKAITQWFHDAMMAGKLKETNLNLITNIYVSLFQGLLFWPQVMTLAPNAEGKELTDKVETVVSIFLASYSLES</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3Z8</accession>
    <name>D0Z3Z8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Membrane-bound lytic murein transglycosylase C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001151</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the transglycosylase Slt family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306354.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001151"/>
    <dbReference type="EnsemblBacteria" id="EEZ40129">
        <property type="protein sequence ID" value="EEZ40129"/>
        <property type="gene ID" value="VDA_001151"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0741">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008933">
        <property type="term" value="F:lytic transglycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000270">
        <property type="term" value="P:peptidoglycan metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024570">
        <property type="entry name" value="Murein_transglycosylaseC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000189">
        <property type="entry name" value="Transglyc_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008258">
        <property type="entry name" value="Transglycosylase_SLT_dom_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11873">
        <property type="entry name" value="Mltc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01464">
        <property type="entry name" value="SLT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00922">
        <property type="entry name" value="TRANSGLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mltc_N" evidence="3">
        <location>
            <begin position="50"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="SLT" evidence="2">
        <location>
            <begin position="210"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF11873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="375" mass="42700" checksum="F2AD6F255BCC3546" modified="2010-01-19" version="1">MKHLWFAVASSIALTACAPSDLDVYGPAEPSKPPVVIPPPPPTTNTNAQEQAFKKLLAYLNEQVKKQWGDDEFLQAGKHRYVKYLDGYRTRAHIDFDTGKIYVSTVSKYAPKETLKEAIVSTLLMPADPAQVDLFSDKTIPLNGKPFLLGQVKDHDGQDIQWEWRANRFADYLIENKLQSKPFKYGTAYYVQIDMVGDHLEQREYQYADLIKRASKQYGIDEDLIYAIVKTESSFNPFAVSHAGAYGLMQVIPKTAGADVFNLVKNKPGIPTKEYLFDPANNIDTGTAYFYILKNRYLKNVQHPTTKHYTMISAYNGGTGGVLATFDPDRDRAMNQINQLNPDQVYWALTNKHPKEEARRYLQKVLHFQKEFNNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z434</accession>
    <name>D0Z434_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Iron(III) ABC transporter solute-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000290</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303955.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000290"/>
    <dbReference type="EnsemblBacteria" id="EEZ39272">
        <property type="protein sequence ID" value="EEZ39272"/>
        <property type="gene ID" value="VDA_000290"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0614">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1473468at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002491">
        <property type="entry name" value="ABC_transptr_periplasmic_BD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01497">
        <property type="entry name" value="Peripla_BP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50983">
        <property type="entry name" value="FE_B12_PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003020068" evidence="1">
        <location>
            <begin position="21"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="domain" description="Fe/B12 periplasmic-binding" evidence="2">
        <location>
            <begin position="44"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="340" mass="37903" checksum="99C399F29900E4D8" modified="2010-01-19" version="1">MKLKATVALVCSLISVSAMATSTTRTVIDDTGAKVVLPNHPIERVADAWYSHTTELMALGEGDKIVATINHPESRPWMFKIQPSLNHALLGQGKIFNIESLLNRDVQLAFVMTGNPQRIAMESVNIPVVQVHFTTLDGLQKTMLLTAKAMGSEKAMVRAKEYNQYLQHQLKRIKKKTEKLTEQQRPKVLHISSLNPLKVDGQGTLISDWISIAGGRNVAEVKGTMQPVSAEQILAWQPDIVILQGDAGDIKQSSEASLLEQLKAVKDGHVLRNPLGVFTWDRYGPESALQIQWAAKAFHPELFKHDNLAKITQEFYQHFFDYSLTPEQASRILQALPPRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z498</accession>
    <name>D0Z498_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Di-/tripeptide transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_000354</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304130.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000354"/>
    <dbReference type="EnsemblBacteria" id="EEZ39336">
        <property type="protein sequence ID" value="EEZ39336"/>
        <property type="gene ID" value="VDA_000354"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3104">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="470322at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904680">
        <property type="term" value="F:peptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17346">
        <property type="entry name" value="MFS_DtpA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005279">
        <property type="entry name" value="Dipep/tripep_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000109">
        <property type="entry name" value="POT_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11654">
        <property type="entry name" value="PTHR11654"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00854">
        <property type="entry name" value="PTR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00924">
        <property type="entry name" value="yjdL_sub1_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="9"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="100"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="139"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="169"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="209"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="235"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="266"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="302"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="351"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="375"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="413"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="459"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="7">
        <location>
            <begin position="1"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ39336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="486" mass="53002" checksum="D7E8AA0926F1E7F3" modified="2010-01-19" version="1">MRLASQPKGLFHLIAIQMWEFFSYYGMRSLLILFLTQKLLMTDHHAYALYGAYTSLVYVTPIIGGYLADRYFGNYWSVVIGALLMVAGHAVLSIPSVGNISMYIALSLIICGYGFFKTNSSCLLGELYTKEHEKSRESGFSISYIGSNVGSALAPIFCGYAAMKWGWHVGFALAGIGMLVGLIIFSTGRRNFTHVKKCNKDALIQKSAGVPHWLIIIVLLALTAFGLVFVLKDLLAGYILAVICAVSFYQIVALYRRSSPSDRSKLNSILYFMIFGTVFWAFDQQGGSSISLFIERNINTDIFGFHIPTAFFQSVNPVAVIVGGGAVAWLWKVLASKSISVRTLTKLNMGLLLLTAGFTLITISSKLAMNTGHTTFLWLFIGLFLIGVAELFIDPVALAAITRLNPQGATSTLAGIYMLMGGSVANYIAANIAEFTASNTPVNADATDLIASAAQYHHVFQSILFVTVAVLVLGLLVDFKNRHKAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z499</accession>
    <name>D0Z499_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PNPLA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000355</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304133.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000355"/>
    <dbReference type="EnsemblBacteria" id="EEZ39337">
        <property type="protein sequence ID" value="EEZ39337"/>
        <property type="gene ID" value="VDA_000355"/>
    </dbReference>
    <dbReference type="GeneID" id="57343265"/>
    <dbReference type="eggNOG" id="COG4667">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="373926at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07208">
        <property type="entry name" value="Pat_hypo_Ecoli_yjju_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045943">
        <property type="entry name" value="DUF6363"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037483">
        <property type="entry name" value="YjjU-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19890">
        <property type="entry name" value="DUF6363"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="1 2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="3">
        <location>
            <begin position="28"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXGXXG" evidence="2">
        <location>
            <begin position="32"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="2">
        <location>
            <begin position="60"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DGA/G" evidence="2">
        <location>
            <begin position="187"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="62"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="332" mass="37289" checksum="79D603BEEB819835" modified="2010-01-19" version="1">MTGTHVSYAVHNTDALSHIGTEVTKVALVTEGGGQRGIFTAGVLDAFLEANFNPFSLLVGTSAGSLNLASYICGQYKHAYRVITEATTNHQFFDVYRFIFGREGLNLDWLVGQTNESLDARLQLNWKQGHENMRYRTVLASASGIMSHRASYFDLDTDNRTLALKASCAIPILNRQPIFSQNEYWVDGGLCAPIPVQEAYERGYRHIVVVRTVPLDVQYDHCWMTSVQQALGKSRAAGVIEMLLEHEDNYRKTQQFLSNPPDDVTIYEIHPQKPLVSKLIGSDISMLNTDYHLGYQTGVYFLNTMGKHMHHQFDQPAANDQLNCIPMANVRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4C8</accession>
    <name>D0Z4C8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000384</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000384"/>
    <dbReference type="EnsemblBacteria" id="EEZ39366">
        <property type="protein sequence ID" value="EEZ39366"/>
        <property type="gene ID" value="VDA_000384"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3683">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010412">
        <property type="entry name" value="DUF1007"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016537">
        <property type="entry name" value="UCP008159_ABC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06226">
        <property type="entry name" value="DUF1007"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF008159">
        <property type="entry name" value="UCP008159_ABC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019988" evidence="1">
        <location>
            <begin position="28"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="218" mass="24799" checksum="4959B60267BBAED3" modified="2010-01-19" version="1">MLSDGKKMKFRWLSIAATLLYSSAGLAHPHSWIDMKTYIHGTEQQITGFTMEWTFDAMTSAYMLDGEDMSPDHKAQTLKQVGDSVMHNMINEHYFTYFYNGEQPIKYKLAENGELTQNRTKLTLTFDLPLSKPQPLTKDSLKVLIFEPSYYVDMSWKKSKDVILDPELAAVCNAEMIEPNPTPEQMSYAMSLPPDADPDNALGQLFTQTVRLHCKPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4G9</accession>
    <name>D0Z4G9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 11">Carboxynorspermidine/carboxyspermidine decarboxylase</fullName>
            <shortName evidence="11">CANS DC/CAS DC</shortName>
            <shortName evidence="11">CANSDC/CASDC</shortName>
            <ecNumber evidence="6 11">4.1.1.96</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">VDA_000427</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 11">
            <text>carboxynorspermidine + H(+) = CO2 + norspermidine</text>
            <dbReference type="Rhea" id="RHEA:34099"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57920"/>
            <dbReference type="ChEBI" id="CHEBI:65070"/>
            <dbReference type="EC" id="4.1.1.96"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>carboxyspermidine + H(+) = CO2 + spermidine</text>
            <dbReference type="Rhea" id="RHEA:34095"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57834"/>
            <dbReference type="ChEBI" id="CHEBI:65072"/>
            <dbReference type="EC" id="4.1.1.96"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 11">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5 11">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10 11">Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.96" evidence="6 11"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304331.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000427"/>
    <dbReference type="EnsemblBacteria" id="EEZ39407">
        <property type="protein sequence ID" value="EEZ39407"/>
        <property type="gene ID" value="VDA_000427"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0019">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="861683at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045312">
        <property type="term" value="P:nor-spermidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008295">
        <property type="term" value="P:spermidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06829">
        <property type="entry name" value="PLPDE_III_CANSDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009006">
        <property type="entry name" value="Ala_racemase/Decarboxylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022643">
        <property type="entry name" value="De-COase2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022644">
        <property type="entry name" value="De-COase2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005730">
        <property type="entry name" value="Nsp_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43727:SF1">
        <property type="entry name" value="PTHR43727:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02784">
        <property type="entry name" value="Orn_Arg_deC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00278">
        <property type="entry name" value="Orn_DAP_Arg_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038941">
        <property type="entry name" value="NspC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50621">
        <property type="entry name" value="SSF50621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="SSF51419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01047">
        <property type="entry name" value="nspC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 11" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="11" id="KW-0456">Lyase</keyword>
    <keyword evidence="11" id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword evidence="11" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0745">Spermidine biosynthesis</keyword>
    <feature type="domain" description="Orn_Arg_deC_N" evidence="14">
        <location>
            <begin position="27"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="Orn_DAP_Arg_deC" evidence="13">
        <location>
            <begin position="241"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="272"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR038941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR038941-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEZ39407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="374" mass="41179" checksum="F8EB20A1778F01DC" modified="2010-01-19" version="1">MKQLATPYFMIDEAALLKNLERIAQLKALSGAKMVLALKCFSTWGVFDTMKPYLDGTTSSGPLEVRLGAETFGGETHGYSVGYSQQDIEAINPFVNKLIFNSLSQLENLRKYAADGISIGVRFNPGISYANQDLANPARQYSRLGVSVDKLSSQALVGVEGGMFHMNCENSNFPAYKRILETISQQFGPYLDNLNWVSLGGGVSFTSDGYPLEELASLLKWFSDKHGVQIYLEPGEAVITKTTDLVVTVVDIVENGMKTAIVDSATEAHRLDTLIYNESGTIREASLDGDYEYIIGSCSCLAGDVFCVAKFDQPLQIGDRLHVMDSGGYTMVKLNWFNGLKMPSIYCRRVDGEIIQLNQFGYDDFKATLSRASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4H1</accession>
    <name>D0Z4H1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hypothetical cytosolic protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000429</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304337.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000429"/>
    <dbReference type="EnsemblBacteria" id="EEZ39409">
        <property type="protein sequence ID" value="EEZ39409"/>
        <property type="gene ID" value="VDA_000429"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1361">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2885">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3292">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3391">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3420">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4719">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4932">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5184">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="57483at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001434">
        <property type="entry name" value="DUF11"/>
    </dbReference>
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</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="33" xmlns="http://uniprot.org/uniprot">
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                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
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            <text>a 1-acyl-sn-glycero-3-phosphate + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphate + CoA</text>
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        </reaction>
    </comment>
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        <text evidence="2">Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 2/3.</text>
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        <text evidence="6">The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.</text>
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</entry>
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                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
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                <person name="Tapia R."/>
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                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
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                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <name>Ca(2+)</name>
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        <text evidence="8">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
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    </dbReference>
    <dbReference type="CDD" id="cd16030">
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        <property type="entry name" value="DUF4976"/>
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        <property type="entry name" value="IDS"/>
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        <property type="entry name" value="Sulfatase_N"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01409">
        <property type="entry name" value="TAT_signal_seq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00523">
        <property type="entry name" value="SULFATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Sulfatase" evidence="9">
        <location>
            <begin position="35"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4976" evidence="10">
        <location>
            <begin position="450"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="8">
        <location>
            <position position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF16347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ39515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="539" mass="60534" checksum="813B2348CBE838D2" modified="2010-01-19" version="1">MELSRRKFLKSTAAVGAVTATSSCFVQAEHSTQHPNVLFLAVDDLNDWIGALGAHPQVKTPNLDRLYKRSTAFRNAHCQVPVCGPSRTALLTGMAPTTTGLYTNKELGIKPFDPVAEQVLGSTPVLPQHFKNNGYYTMASGKISHHGTADYRHKEQWDEEIPLYVIGPRDEHLKANGYGYGSYGVDDHKYYPFPVGGGQIIQSQEYGPGTRGFSLCSGALDRHDIPNGGVMPDEYFADWTVERLQRHYEKPFFLACGFIRPHVPYTAPREYFDMFPLESIIVPETIEKEMTDIPLMGKALALGIIPGGDAAAVNKLGIRKELVQAYLACIAFMDAQVGKVLDALEKSPYANNTIVMFWGDHGQNFGEHMNYRKQTLWQESTRVPLMIRLPQQEKGQVCDEAVSLLDLYPTLIELCHLPKVATNEGISLKPLLNNPRFDRKIPAVTTYGYQCHAIRDEQYTYIRYRDGSEELYDRNLDPNEHHNLASDPNYQVIKQAMKQWLPVNNALPYGMVDFDKEGGDFITRILAGFEKEGIPTNLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4T4</accession>
    <name>D0Z4T4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">IncF plasmid conjugative transfer pilus assembly protein TraK</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000167</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306493.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39151">
        <property type="protein sequence ID" value="EEZ39151"/>
        <property type="gene ID" value="VDA_000167"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2375">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1450250at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010563">
        <property type="entry name" value="Pilus_assembly_TraK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014126">
        <property type="entry name" value="TraK_Ftype"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06586">
        <property type="entry name" value="TraK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02756">
        <property type="entry name" value="TraK_Ftype"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019420" evidence="1">
        <location>
            <begin position="22"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="243" mass="26324" checksum="10D5382D8E4C07BB" modified="2010-01-19" version="1">MSKYPAVLGLCALIFAPTVLATAPNTVLFSDNETVSVNLSSLDINRLVVKDDKITSVTCPTGFCTMPANPVDESGTGAPVDPQGAGLISLNVLEPFTLYITTEKGRSFGVFVRPLAVPAITTVFLSTERDTQKAQEFEKQSPYTQTLAALISHMIKETIPEGFAFQRLTVKKPIEQAKLLLTPIASYQGEHLTGISVKISNKTAQYIQVEPTSFYKAGVKAVSFSSMSIPPHGSIYMYQIQGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4V3</accession>
    <name>D0Z4V3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Type III export protein YscF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000186</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MxiH/PrgI/YscF family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306547.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000186"/>
    <dbReference type="EnsemblBacteria" id="EEZ39170">
        <property type="protein sequence ID" value="EEZ39170"/>
        <property type="gene ID" value="VDA_000186"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031YA0">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2009480at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030257">
        <property type="term" value="C:type III protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030254">
        <property type="term" value="P:protein secretion by the type III secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021123">
        <property type="entry name" value="T3SS_needle-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037203">
        <property type="entry name" value="T3SS_needle-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011841">
        <property type="entry name" value="T3SS_needle_YscF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09392">
        <property type="entry name" value="T3SS_needle_F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140129">
        <property type="entry name" value="SSF140129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02105">
        <property type="entry name" value="III_needle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0843">Virulence</keyword>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="12"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="82" mass="9270" checksum="9589DDF43F17783E" modified="2010-01-19" version="1">MSFYDASNRVYLDDVKTKLEEQAKAANEAVNKAIKNLETNADDPSKLAELQHTINKWSVIYNINATTTRAIKDVMQSILQKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4V4</accession>
    <name>D0Z4V4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Type III secretion inner membrane protein YscD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000187</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306550.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000187"/>
    <dbReference type="EnsemblBacteria" id="EEZ39171">
        <property type="protein sequence ID" value="EEZ39171"/>
        <property type="gene ID" value="VDA_000187"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1716">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1151319at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012843">
        <property type="entry name" value="T3SS_YscD/HrpQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032030">
        <property type="entry name" value="YscD_cytoplasmic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032034">
        <property type="entry name" value="YscD_ppl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16697">
        <property type="entry name" value="Yop-YscD_cpl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16693">
        <property type="entry name" value="Yop-YscD_ppl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SSF49879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02500">
        <property type="entry name" value="type_III_yscD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="Yop-YscD_cpl" evidence="3">
        <location>
            <begin position="7"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="Yop-YscD_ppl" evidence="2">
        <location>
            <begin position="170"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="433" mass="48228" checksum="FE80F20B6C3DEB33" modified="2010-01-19" version="1">MQQWKIRILSGVHAGVEVTLPNDSLVLGSDDFTADLVLTDSDIKASHLVLVCDGDTVLLRDCDEVSINNESVTVDANEIELSRNALVSVGRLTFAVGHLEDDLAIDITTEAAEKQATPVSHKPSSGWKRTVLIGLMCSLIPSVIFAGVWYSQIRASNSDAITEAEPIVLVRNILSELKLDDVRVEWNATARQAVLEGYVEDRTAKLQLLGRIDALGINYKSDLRTMEEIRRGVRFILRNLGYHQVKVDNGEEIGTLLLTGYIDDASRWSQVEQILERDVPGLVAWKAELQRAGAYMDTLKALLEKAELLKKVQLVTSGDRIEVRGELDDIETTRFYGVTRDFREQYGEKPYLVLKSIPKVSKGTNIDFPFRSVNFGQVPYVILTDNVRYMVGARTPQGYRISSVTPSGIELVKGGRVITIDLWYEGENTNDKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4W5</accession>
    <name>D0Z4W5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type III secretion protein (YscP)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000198</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306582.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000198"/>
    <dbReference type="EnsemblBacteria" id="EEZ39182">
        <property type="protein sequence ID" value="EEZ39182"/>
        <property type="gene ID" value="VDA_000198"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031N24">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1435536at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013354">
        <property type="entry name" value="T3SS_YscP_C"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02514">
        <property type="entry name" value="type_III_yscP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="416"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="442" mass="48958" checksum="8E8C18D5DD10BC7F" modified="2010-01-19" version="1">MRVKNDHPNTTERPQQVQQRPVNQVSEELESRFNNALKPTQAESEHESATSRLFAAVLNADKLDGMKHKGKISSAIPATGKEQLEGSQEHPENLKDQPANEKSDADLHPEKPSHDLSERETVQVLDNKDQNEESHSETSERPAKEPHSDTAKPVKLHSLIEQSVGSKETDKSQPLASNSAAEKDSNNKQVSSVPLDNGSSRDPKIPMISLPNALKDQVLPIQTDQANLRNKTEPSTVQSVLQGQLHKLDAAAHKPDPAAKDTAAIVDSKAALSALEEKVKAVKHIELRHPSSESDAKLHPTANLSQSTAQGDIILKNVETHAPQNRAQDVNELINKLVDKIYVSLPSANDKEVRLLLNEGQLKGGEISIKQDSSGYSVLIKQEHALSLINQTAKQELTERLQRLGIDQPIRIAVSEQMNQQQDQQRSRQQRSIYDEWKPEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z594</accession>
    <name>D0Z594_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetate/propionate kinase</fullName>
            <ecNumber evidence="2">2.7.2.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000144</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.2.1" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000144"/>
    <dbReference type="EnsemblBacteria" id="EEZ39128">
        <property type="protein sequence ID" value="EEZ39128"/>
        <property type="gene ID" value="VDA_000144"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031PFH">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008776">
        <property type="term" value="F:acetate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018880" evidence="1">
        <location>
            <begin position="29"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="255" mass="27856" checksum="131D3AB52BBC207F" modified="2010-01-19" version="1">MNNKKVIALFISAAVLAPMMGCQSTQQAQRNSLDANVVDVNDKMVGMIRGVVLTYDPVKVKPEQLKNQGVQVAGSGLVAGGLTGAMLSSDRTGAAIGVGAAVIGGLALLADNLSEPDLVDAYRYTVQTQKGGELLEIYQVDQAPLIEGSPVFVRSYQSGRLTVRLDTTQGRSFQRAHDTQYQGKGRLTAQERQEMLEDAAFDRKLRTDQRNEETENVVHEQYRKAVKTETDKLNSTIDARNQSLRNSKTTNININ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5A0</accession>
    <name>D0Z5A0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_000150</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Nucleoid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the histone-like protein H-NS family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306989.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000150"/>
    <dbReference type="EnsemblBacteria" id="EEZ39134">
        <property type="protein sequence ID" value="EEZ39134"/>
        <property type="gene ID" value="VDA_000150"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2916">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1911889at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009295">
        <property type="term" value="C:nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027444">
        <property type="entry name" value="H-NS_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037150">
        <property type="entry name" value="H-NS_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001801">
        <property type="entry name" value="Histone_HNS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027454">
        <property type="entry name" value="Histone_HNS_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00816">
        <property type="entry name" value="Histone_HNS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002096">
        <property type="entry name" value="HnS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00528">
        <property type="entry name" value="HNS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNS" evidence="9">
        <location>
            <begin position="85"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="DNA-binding region" evidence="6">
        <location>
            <begin position="110"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="78"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="26"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="80"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR002096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR002096-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ39134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="127" mass="14889" checksum="67F393582F0F5115" modified="2010-01-19" version="1">MSDVFAILLNLRSLRAQSRELTLEQLQEGLEKLTQVTNERVQEEEQLRAENKEKEEKLAMYREMLIADGIDPEELLNNLESKSATKKRPSRPAKYRYTDENGEEKTWTGQGRTPKFLQDKNLDDYLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5F8</accession>
    <name>D0Z5F8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TriK protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000065</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000006">
        <property type="protein sequence ID" value="EEZ39010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39010">
        <property type="protein sequence ID" value="EEZ39010"/>
        <property type="gene ID" value="VDA_000065"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3505">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032689">
        <property type="entry name" value="TraG-D_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12696">
        <property type="entry name" value="TraG-D_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="TraG-D_C" evidence="2">
        <location>
            <begin position="408"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="616" mass="70317" checksum="DA39BCAAD3E7FDFF" modified="2010-01-19" version="1">MYDYLNFFYQNPILISLISGISITTSIYVALSSRFLRKENLTGLELLWNTITTRYFPVVVMTHISIICSIYVISNIIYKRSDTLFYLKLLSDKYLTTVAQFNILYPLILIIAPIVLFSINRVLIPELVKIKEKRIIRQSEDKLSDIREEITELSSIEFVPSDYYKDDFFFFGLNEENEPIYLSDKDFSSRHAKILGPSQTGKGVGLGVLIDQAIKKGWGVWFNDIKPDDFIYHIMNQACKESGRKLNYLDLNGTHGTYEPFKNGTVRQREERIKRACKLNDTGTNADHYKLGNRQILDLLMPYWDGSLTHLTELLNCRSLPSCLSDEDKEMIKEQGGTLRERIREFSKLDVLKPSNNRQQFIISDLMDEGSVVYIKGSLTDDLVRNANIALLDEFIQFGLGKKQNKQIFMVLDEVRFLVTDKLANSLATLLSKKINMAIAYQAKNDLANSPDQTLNVGSIMNGIETNTLITMSYRGHDEETAKWIAGMTGTKRLSITKSDHVETNQFGVETKTGKRTYGQDQEYMINTNRILSFNPRVGAFINGGSLACIIKTCWIPVKEFLDYPSEAVPSNDMIIDTHSDNLVEEISAHKHEEISSNDVKKINDEAEALFKQMDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVH7</accession>
    <name>D0YVH7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA-uridine aminocarboxypropyltransferase</fullName>
            <ecNumber evidence="1">2.5.1.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_001557</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.5.1.25" evidence="1"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298274.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001557"/>
    <dbReference type="EnsemblBacteria" id="EEZ40531">
        <property type="protein sequence ID" value="EEZ40531"/>
        <property type="gene ID" value="VDA_001557"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3148">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1719529at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016432">
        <property type="term" value="F:tRNA-uridine aminocarboxypropyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005636">
        <property type="entry name" value="DTW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039262">
        <property type="entry name" value="DTWD2/YfiP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21392">
        <property type="entry name" value="PTHR21392"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03942">
        <property type="entry name" value="DTW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01144">
        <property type="entry name" value="DTW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="DTW" evidence="5">
        <location>
            <begin position="1"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="206" mass="23194" checksum="25991A956D5247FA" modified="2010-01-19" version="1">MSRYCKQCGKAIKACICHWIQTIDAKTELWILQHPSETKRAIGTARILTLSLPNSRLFVGEDFSDHQELNQLLADPCRQAYVIYPGEGALPISQVAQSAADASAIQTLILLDGTWKKAFKMWQLSSNLQQLPAVMLDNADNGNYRIRKSPKENGVSTVEAGFLALSAMEPPQSRYIPLLETFERMIDFQIKQMPEGVFERNYGDEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVJ7</accession>
    <name>D0YVJ7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Fatty acid metabolism regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001577</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001577"/>
    <dbReference type="EnsemblBacteria" id="EEZ40551">
        <property type="protein sequence ID" value="EEZ40551"/>
        <property type="gene ID" value="VDA_001577"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2186">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000062">
        <property type="term" value="F:fatty-acyl-CoA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019217">
        <property type="term" value="P:regulation of fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014178">
        <property type="entry name" value="FA-response_TF_FadR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028374">
        <property type="entry name" value="FadR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008920">
        <property type="entry name" value="TF_FadR/GntR_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43537:SF10">
        <property type="entry name" value="PTHR43537:SF10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07840">
        <property type="entry name" value="FadR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48008">
        <property type="entry name" value="SSF48008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="FadR_C" evidence="4">
        <location>
            <begin position="1"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="171" mass="20201" checksum="C8A28CA9233524D0" modified="2010-01-19" version="1">MRYAVKGNAEESSKLIQHVIESCEKLLAAESFAEFIEENEDKVELLQEVKKIVDKYGKDDPELCEAICRARAFNFYDYRMFQGMAKCSNNTLYVLTINGLRKIYTRVGGYYFMKPEACQLALSYYRDMQAYCDNQQPELVAERIRTYGRDSGAIWFMHRDEIMRYMHEEEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVP9</accession>
    <name>D0YVP9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pantothenate synthetase</fullName>
            <shortName evidence="5">PS</shortName>
            <ecNumber evidence="5">6.3.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Pantoate--beta-alanine ligase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Pantoate-activating enzyme</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">panC</name>
        <name evidence="6" type="ORF">VDA_001214</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>(R)-pantoate + ATP + beta-alanine = (R)-pantothenate + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10912"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15980"/>
            <dbReference type="ChEBI" id="CHEBI:29032"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57966"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.2.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Cofactor biosynthesis; (R)-pantothenate biosynthesis; (R)-pantothenate from (R)-pantoate and beta-alanine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="5">The reaction proceeds by a bi uni uni bi ping pong mechanism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the pantothenate synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.1" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297652.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001214"/>
    <dbReference type="EnsemblBacteria" id="EEZ40192">
        <property type="protein sequence ID" value="EEZ40192"/>
        <property type="gene ID" value="VDA_001214"/>
    </dbReference>
    <dbReference type="GeneID" id="57339930"/>
    <dbReference type="eggNOG" id="COG0414">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1661843at2"/>
    <dbReference type="UniPathway" id="UPA00028">
        <property type="reaction ID" value="UER00005"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004592">
        <property type="term" value="F:pantoate-beta-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00560">
        <property type="entry name" value="PanC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00158">
        <property type="entry name" value="PanC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003721">
        <property type="entry name" value="Pantoate_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042176">
        <property type="entry name" value="Pantoate_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21299:SF1">
        <property type="entry name" value="PTHR21299:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02569">
        <property type="entry name" value="Pantoate_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00018">
        <property type="entry name" value="panC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 5" id="KW-0566">Pantothenate biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="37"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="30"/>
            <end position="37"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="149"/>
            <end position="152"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>(R)-pantoate</name>
            <dbReference type="ChEBI" id="CHEBI:15980"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="186"/>
            <end position="189"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="296" mass="33321" checksum="5828CC83120596BA" modified="2010-01-19" version="1">MQTFADIASMREQVRTWRREGRRIAFVPTMGNLHDGHMRLVRKARKYADIVVVSIFVNPMQFDKPEDLQNYPRTLDDDLTKLDAEHVDVVFTPTPEMMYPQGLESQTFVEVPILSQMLEGALRPGHFRGVATIVTKLFNIVQPDVACFGEKDYQQLALIRQMVKDMAMDIEIVGVPTVRELDGLALSSRNGYLTVDERQRAPVLARTMRWVSSQMRGGRTDYDDLIVDANDQLRAAGLQPDASFIRDAVTLQPVSETSTKAVILMAAQLGKARLIDNQVVDLTPIQTTTVTEAVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVQ2</accession>
    <name>D0YVQ2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glutamyl-Q tRNA(Asp) synthetase</fullName>
            <shortName evidence="5">Glu-Q-RSs</shortName>
            <ecNumber evidence="5">6.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">gluQ</name>
        <name evidence="8" type="ORF">VDA_001217</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001217"/>
    <dbReference type="EnsemblBacteria" id="EEZ40195">
        <property type="protein sequence ID" value="EEZ40195"/>
        <property type="gene ID" value="VDA_001217"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0008">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004812">
        <property type="term" value="F:aminoacyl-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006424">
        <property type="term" value="P:glutamyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01428">
        <property type="entry name" value="Glu_Q_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022380">
        <property type="entry name" value="Glu-Q_tRNA(Asp)_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000924">
        <property type="entry name" value="Glu/Gln-tRNA-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020058">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00749">
        <property type="entry name" value="tRNA-synt_1c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00987">
        <property type="entry name" value="TRNASYNTHGLU"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03838">
        <property type="entry name" value="queuosine_YadB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 6" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="3 5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 5 6" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="tRNA-synt_1c" evidence="7">
        <location>
            <begin position="54"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Glutamate binding" evidence="5">
        <location>
            <begin position="55"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="5">
        <location>
            <begin position="58"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="5">
        <location>
            <begin position="274"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="218"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="277"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ40195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="339" mass="38247" checksum="3C58686E1F5B0028" modified="2010-01-19" version="1">MQNHCTHILDTKLISFLLKWANQFGCPIRSINRKPFNLTALFVMSTERNHQYVGRFAPSPSGPLHFGSLVAALGSYLQAKSQQGRWIVRIEDLDPPREMPGAADDILRTLDAFGLHWDGELMYQSQRLDVYQSQVEHWLVTGDAYYCQCTRKQIKDGGGYYLGTCRHLNHGADESSIRLKIDNPITHFIDQLHGRIDIPAQLAAEDFIIRRRDGLFAYNLAVVLDDIEQGVTEVVRGADLIEPTGRQISLYQLLQQPEVSYLHLPLATMDNGCKLSKQNHAPAINKQDPRPQLLAAMHFLAMQPPNELASNSIEEILSWGIAHWQVDNLPQATAITLAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVQ6</accession>
    <name>D0YVQ6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 13">Penicillin-binding protein 1B</fullName>
            <shortName evidence="13">PBP-1b</shortName>
            <shortName evidence="13">PBP1b</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12 13">Murein polymerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">VDA_001221</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 13">Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>[GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-di-trans,octa-cis-undecaprenyl diphosphate + beta-D-GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate = [GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-di-trans-octa-cis-undecaprenyl diphosphate + di-trans,octa-cis-undecaprenyl diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23708"/>
            <dbReference type="Rhea" id="RHEA-COMP:9602"/>
            <dbReference type="Rhea" id="RHEA-COMP:9603"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58405"/>
            <dbReference type="ChEBI" id="CHEBI:60033"/>
            <dbReference type="ChEBI" id="CHEBI:78435"/>
            <dbReference type="EC" id="2.4.1.129"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 13">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">In the C-terminal section; belongs to the transpeptidase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">In the N-terminal section; belongs to the glycosyltransferase 51 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001221"/>
    <dbReference type="EnsemblBacteria" id="EEZ40199">
        <property type="protein sequence ID" value="EEZ40199"/>
        <property type="gene ID" value="VDA_001221"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0744">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="652304at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009274">
        <property type="term" value="C:peptidoglycan-based cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008658">
        <property type="term" value="F:penicillin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008955">
        <property type="term" value="F:peptidoglycan glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009002">
        <property type="term" value="F:serine-type D-Ala-D-Ala carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3810.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001264">
        <property type="entry name" value="Glyco_trans_51"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011813">
        <property type="entry name" value="PBP_1b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036950">
        <property type="entry name" value="PBP_transglycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001460">
        <property type="entry name" value="PCN-bd_Tpept"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028166">
        <property type="entry name" value="UB2H"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00912">
        <property type="entry name" value="Transgly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00905">
        <property type="entry name" value="Transpeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14814">
        <property type="entry name" value="UB2H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002799">
        <property type="entry name" value="PBP_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02071">
        <property type="entry name" value="PBP_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="13" id="KW-0133">Cell shape</keyword>
    <keyword evidence="13" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="8 13 20" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="16" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="13" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="7" id="KW-0645">Protease</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13 20" id="KW-0808">Transferase</keyword>
    <keyword evidence="16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="98"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="UB2H" evidence="19">
        <location>
            <begin position="146"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="Transgly" evidence="18">
        <location>
            <begin position="241"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="domain" description="Transpeptidase" evidence="17">
        <location>
            <begin position="505"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="9"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="30"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="15">
        <location>
            <begin position="74"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for transglycosylase activity" evidence="14">
        <location>
            <position position="266"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate; for transpeptidase activity" evidence="14">
        <location>
            <position position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR002799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR002799-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF00912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF14814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="EEZ40199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="847" mass="94264" checksum="0073561AA779569C" modified="2010-01-19" version="1">MMTKLPANISHISAHNQSLSQRKCAQRPSSRRKKTGDEGEDKKTPTRKPPAKKAPAKKPEPKKTAEKKPAVKKAPSKKTSSKKKKAKTAKVSTWQKKLAWLAFKIGLVVLAILLVIGIYLDNVVRSKMDGQTWQLPSVVYGRVLTLEPGLTLSLPALKRELDVLQYHKVAQPNQIGEYAASSHSIEFIRRAFDFPTGKEGRRHVKINFSGSEISSIVDMSNNRKLGYVRLEPKMLGMLGATSDEQRMFLPLNQFPKLLSQALITTEDRDFYEHDGVSPMAIARALFVNLRAGRTVQGGSTLTQQLAKNLFLSRERSLWRKIREAYIAVILDYRYSKDRILEAYLNEVYMGQNGGKEVHGFALGARLYFGRPVQELAPEQLAMLVGMVKGPSQFNPWRHPERTRERRDLVLRLLMDNDIISGQEYELAASKPLGVQKAPQIATRQPAYFDLLRRELRDSVGDIYQLGYGLKIFSTLDPVSQQDAEDAVEAMVPQLNKRAGMQVETAMVAADRMSGEIRAMIGGSRTGYAGFNRALDASRQIGSLVKPAVYLSALRQPNRYTLATTLDDKPIVLRGSNGDNWKPRNYDRKYRGAVPLYLALAKSLNVPTVNLGLQVGLKDVIHTLSELGVNPDEVPHVPSILLGSFTLTPLEVTQMFQSIASGGKRAPLSALRAVMTKEGKVVYQHVPKYQQVVPLQAAWLTTYAMKRVVSEGTARYLQSKFGYASLAGKTGTTDKSRDSWFAGADGREVVAIWVGRDDNKSVRLTGSSGALRIYGEYLTRRKPEPLRLPWPQQIRTVKYQRLSNGTLRFDCGGNVSLPAWDQNGSLKAACQGGGSKQPAAWIQNMFAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVT1</accession>
    <name>D0YVT1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_001996</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001996"/>
    <dbReference type="EnsemblBacteria" id="EEZ40964">
        <property type="protein sequence ID" value="EEZ40964"/>
        <property type="gene ID" value="VDA_001996"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1132">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="39"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="162"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="184"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="270"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="298"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="40"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="324" mass="36615" checksum="7A8E3AB0119EF69E" modified="2010-01-19" version="1">MFKRFEKLTQAFPKDDPSQPPNTIFAFCRYYTRGFEKPLIMVALLSAVIAMIEVALFGFMGQLVDWLAASDPKTFLSENAGKLFGISLVILIVMPLLVLLSSLLSHQSLLGNYPMSIRWKAHRYLLNQSLSFYQDDFAGRIATKVMQTSLAVRETVMKTADVFVYVLVYFTSMLVILAQADWLLMIPMVAWLIAYIAIQLHFVPKLKQVATEQADARSLMTGRIVDSYTNISTVKLFSHSTRETDYAEDGMKGFLKTVYQQMRLVTGFDVCVQLANYSLLFIISALSIYLWMQGAIEIGAIAIAISLALRINGMSMWIMWDNVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVW7</accession>
    <name>D0YVW7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative conserved exported protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001248</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001248"/>
    <dbReference type="EnsemblBacteria" id="EEZ40226">
        <property type="protein sequence ID" value="EEZ40226"/>
        <property type="gene ID" value="VDA_001248"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3079">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011978">
        <property type="entry name" value="UPF0149"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036255">
        <property type="entry name" value="YgfB-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03695">
        <property type="entry name" value="UPF0149"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101327">
        <property type="entry name" value="SSF101327"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="157" mass="17110" checksum="9AF86D264F3A02CD" modified="2010-01-19" version="1">MICGGLALDNQMWLGPVCDYANEGEPLTDGAKTFTETLFATTSQELVGGDFDFTLLLPSDEADLFERAEALTEWVSSFMSGFGLVGVNTSQLPEAVTEALADLRDITQLGIDEDDDMEEQAALFEQVTEHVRMCVLTCHAELGQSVVDENDSKPTLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVX4</accession>
    <name>D0YVX4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FAD assembly factor SdhE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001255</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SdhE FAD assembly factor family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297738.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001255"/>
    <dbReference type="EnsemblBacteria" id="EEZ40233">
        <property type="protein sequence ID" value="EEZ40233"/>
        <property type="gene ID" value="VDA_001255"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2938">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2055100at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005631">
        <property type="entry name" value="SDH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036714">
        <property type="entry name" value="SDH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03937">
        <property type="entry name" value="Sdh5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109910">
        <property type="entry name" value="SSF109910"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="86" mass="9871" checksum="F536613162B7E052" modified="2010-01-19" version="1">MLSADDKARVKWACRRGMLELDVIIMPFFEECFDGLSEQEQQDFIALLGCDDPDLFKWVMNHGRSEDPALAVMVDKIVAHNNSKLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW29</accession>
    <name>D0YW29_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Tyr recombinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001292</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297809.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001292"/>
    <dbReference type="EnsemblBacteria" id="EEZ40267">
        <property type="protein sequence ID" value="EEZ40267"/>
        <property type="gene ID" value="VDA_001292"/>
    </dbReference>
    <dbReference type="OrthoDB" id="851328at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0229">DNA integration</keyword>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyr recombinase" evidence="3">
        <location>
            <begin position="180"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="486" mass="55463" checksum="6C5F41A58BAC1650" modified="2010-01-19" version="1">MVMNSLKIDIKSRPASSESDSHDNDELCLFLYGNGDVNWFATDFLMSNKIPRASKKGAKGLIRYFLEYIEYYENWKYGDTQGKPVSIGTVTDEHFYDFVRYIEDDIGLNRNAIAKRVRMALRFLEFIQENYHLRYTLIAISDADGHYSSKGLVNAKRKISSHNKKSFLHHDCIPHSEDYGSRSPITEAAIESLYNDLDKLEDEGEEFLFEFLSTLIGLLEATGIRVSEAANIDAHTIEILRAQVNASLASKAVELNDIIRLNKLTVDAKSLKTAEAIYRKSAVGGNNNQLVWIKIKTTKGNNKNTFRIIPISFTAAQYLVRFYDDYILNELDRTNEGLCRINRAKFGKLFVHHRSHLPMTGVMISSLFYEIFGRKYKSKHKRNPHLFRHRFITLLTVQQLKALNSNMGGTQLARLILKRIQGLTGHASIDTMLHYVELAEAELEIDKLSGFDSTTREHLVSELGEEHVAQLEKGLILKQVKETLTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW80</accession>
    <name>D0YW80_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Zinc metalloprotease</fullName>
            <ecNumber evidence="9">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">VDA_001365</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the peptidase M50B family.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="9"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001365"/>
    <dbReference type="MEROPS" id="M50.004"/>
    <dbReference type="EnsemblBacteria" id="EEZ40340">
        <property type="protein sequence ID" value="EEZ40340"/>
        <property type="gene ID" value="VDA_001365"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0750">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004387">
        <property type="entry name" value="Pept_M50_Zn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008915">
        <property type="entry name" value="Peptidase_M50"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42837">
        <property type="entry name" value="PTHR42837"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13180">
        <property type="entry name" value="PDZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02163">
        <property type="entry name" value="Peptidase_M50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00054">
        <property type="entry name" value="TIGR00054"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 11" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="11" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6 9" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="98"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="376"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="426"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="10">
        <location>
            <begin position="114"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="10">
        <location>
            <begin position="210"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ40340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="450" mass="49082" checksum="75C77F856DF237B1" modified="2010-01-19" version="1">MGFLWNLGAFLLALGILIAVHEFGHFWVARRCGVYVERFSIGFGKAIWQRKGKDGTEYTLAMIPLGGYVKMLDERVEAVPEHQRHMAFNNKKLWQRSAIVAAGPFANFVFAVFAYWVVYLIGVPAVKPVIGEVAPQSIAAQGGIAPGMELKSISGIETPDWESVNMAMISHIGDKQMAVTLTEPHSNIDVKRTLNLTDWSYDPERENVLTTLGLTPYTPAITLVISQLVDNGAAINAGFQLNDKIIAVDGEPIKQWQTFADLVKANPGKTLNVEVLRDNAPLTLALTPAVKDLKDGSKVGYVGIAPKVDAWPEDYRINLQFGPIESVAKATEKTWQLVTLTFDMVTKLVTGDVAIKNLSGPISIAKGAGMTADFGLVYFLGFLALISVNLGIVNLLPLPVLDGGHLMFFAIEAVTRRPVSEKIQDIGYRVGSAILVALMAIALFNDFTRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWA6</accession>
    <name>D0YWA6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">MutT protein [7,8-dihydro-8-oxoguanine-triphosphatase]</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_001184</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the Nudix hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297590.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001184"/>
    <dbReference type="EnsemblBacteria" id="EEZ40162">
        <property type="protein sequence ID" value="EEZ40162"/>
        <property type="gene ID" value="VDA_001184"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0494">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1538300at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008413">
        <property type="term" value="F:8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003561">
        <property type="entry name" value="Mutator_MutT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00586">
        <property type="entry name" value="mutt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="5">
        <location>
            <begin position="5"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="8-oxo-dGTP binding" evidence="2">
        <location>
            <begin position="38"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>8-oxo-dGTP</name>
            <dbReference type="ChEBI" id="CHEBI:77896"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>8-oxo-dGTP</name>
            <dbReference type="ChEBI" id="CHEBI:77896"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>8-oxo-dGTP</name>
            <dbReference type="ChEBI" id="CHEBI:77896"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR603561-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR603561-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="135" mass="14992" checksum="F34189D032D82077" modified="2010-01-19" version="1">MTDKKRVWIAAGIILNPTGDKIFITRRAANAHQGGFWEFAGGKVEANETAEQAVIRELQEEVGITATHIEPFIALEHDYPDKALTFDFFVIRQFSGEAYGKEGQPGQWVAISELKDYPFPAANDVVLEKILTVLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWF2</accession>
    <name>D0YWF2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Hypothetical sulfate permease family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_001400</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Membrane</location>
            <topology evidence="1 5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001400"/>
    <dbReference type="EnsemblBacteria" id="EEZ40375">
        <property type="protein sequence ID" value="EEZ40375"/>
        <property type="gene ID" value="VDA_001400"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0659">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008271">
        <property type="term" value="F:secondary active sulfate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001902">
        <property type="entry name" value="SLC26A/SulP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11814">
        <property type="entry name" value="PTHR11814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00815">
        <property type="entry name" value="sulP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="24"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="122"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="172"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="197"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="265"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="345"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="395"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="6">
        <location>
            <begin position="441"/>
            <end position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="568" mass="60553" checksum="E352117E5BE0E3D9" modified="2010-01-19" version="1">MLLFQALSEAWKDGYSFSKFRSDIISGITVGIVAIPLGMALAIAVGVPPQHGLYTVIIAGFLAALLGGSRFNITGPTAAFVVILLPITQKYGLTGLMVATMMSGIILLLMGVFRLGQLVKYVPYPVTTGFTAGVGFVIAFLQLKDLLGLHVLTSPIHFPEKVMAYVDALPSINYADAAVGLVTIFTFIGWAKLKNRIPPHVVALVVGTVLALVINKFGPVHVSLLGEKFSYHIGDLVGHGIPQVLPQFVPLWQHDGLNWSLIVELLPAAFTIAMLGSIESLLCAVVADGMTSTKHNPNAELVGQGLANMIVPFFGGIPATAAIARTATNIRAGAFSPISAIVHSLFVLAAMIALAPVLSYVPMCALAGLLIMVAWNMSEAPHFVHTLKVAPRRDVAVLLTCFILTVVVDMVVAVVVGLLLAGLLFIQRIASLTTVTVVQDKQEHLDFGPDVVVYDINGPLFFAASERAFSAIEHSTIDTRAVVLDFSDVTTIDITAIHAFEAALDRLSDFPVCLLGVAPHVEKKLRNAGIFNAQNVRVFSSTEALRSHLTLSHENNSADKSTLSPVSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWK6</accession>
    <name>D0YWK6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative polysaccharide polymerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001497</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298160.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001497"/>
    <dbReference type="EnsemblBacteria" id="EEZ40471">
        <property type="protein sequence ID" value="EEZ40471"/>
        <property type="gene ID" value="VDA_001497"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5033A5I">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="166"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="200"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="251"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="284"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="313"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="338"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="397" mass="47154" checksum="5FCE0853442CB7DC" modified="2010-01-19" version="1">MIYYVIFGILAIFSFTDNLKDQRYSSLSFIISFFILFLFGSLRYDTGWDFATYRYYFERVDTIHVFLTNGFSPSVYFDFGFKLLISIIKSLGLGFQSLIFICNLFVISCLYYFTNRNIKYKNSAILLFYSLCYLFINLSILRQGIAAGFLLLAIDNNFNNKSNYKTYSYLFLSILFHFSSILFIPLIFISQIFKVNRKTFLLFISSIIFIAIINISVFEIFFHTFHSIIPNNLNEKFELYINSPRFGTSRAIGFGFIEKVFFLILLFHYVYIRNNLTYKEAKNINLIILMLLSYFAVYVLFIDIQVIYTRLKFYFMIIASCYYPLFIYEFLNTRLSKQLGVSICILFSLINLYNTLRFEPNKIVFIPYQTIVTELPSYLNKDYYRIDRAQEIIKENQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWM5</accession>
    <name>D0YWM5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative glycosyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001516</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298197.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001516"/>
    <dbReference type="EnsemblBacteria" id="EEZ40490">
        <property type="protein sequence ID" value="EEZ40490"/>
        <property type="gene ID" value="VDA_001516"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1216">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="730335at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="279" mass="32550" checksum="201533AAC8385D52" modified="2010-01-19" version="1">MECNQKLKEISILIVIYNKKLEESSSFQSIINSLSLVDKGLNVVIWNNGPVSILDEAERYKEIFFEETLYNEGLAILYNKFIDKYPAEKFLILDDDSTFKVDFITKLLLSKNEISLPLIIAGECIRYPRYKGKIVNNNSVLNETKSLISIGSGLCISDKVVELMIKKYGSVFDENFYLYGVDSTFFYRLNDIDIKSINISGEIYHSLSKYEPESDKRKKFRFIERGYDLSLQLKYYPSIKIIKSVFKHTLSLLFNYELRLILDFLKCYLNGYHPRKKIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWM8</accession>
    <name>D0YWM8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">dTDP-glucose 4,6-dehydratase</fullName>
            <ecNumber evidence="4 5">4.2.1.46</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_001519</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>dTDP-alpha-D-glucose = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H2O</text>
            <dbReference type="Rhea" id="RHEA:17221"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57477"/>
            <dbReference type="ChEBI" id="CHEBI:57649"/>
            <dbReference type="EC" id="4.2.1.46"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 5">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.46" evidence="4 5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298203.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001519"/>
    <dbReference type="EnsemblBacteria" id="EEZ40493">
        <property type="protein sequence ID" value="EEZ40493"/>
        <property type="gene ID" value="VDA_001519"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1088">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="707977at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008460">
        <property type="term" value="F:dTDP-glucose 4,6-dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009225">
        <property type="term" value="P:nucleotide-sugar metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05246">
        <property type="entry name" value="dTDP_GD_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005888">
        <property type="entry name" value="dTDP_Gluc_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01181">
        <property type="entry name" value="dTDP_gluc_dehyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="6">
        <location>
            <begin position="4"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="353" mass="39660" checksum="8BDC09270DF4FED7" modified="2010-01-19" version="1">MKILVTGGAGFIGSAVVRHIINNTQDSVVNVDKLTYAGNLESLLSVENDERYAFEQVDICDRAELDRIFAKHQPDAVMHLAAESHVDRSIDGPAAFIETNIIGTYTMLEAARQYWNQLDADHKSAFRFHHISTDEVYGDLEGTDDLFTETTSYSPSSPYSASKASSDHLVRAWLRTYGLPTIVTNCSNNYGPYHFPEKLIPLMILNALEGKQLPVYGNGMQIRDWLYVEDHASALYTVVTQGEIGETYNIGGHNEKANIEVVKTICSLLEELVPNKPQGIAQYQDLITYVTDRPGHDVRYAIDATKIAAELGWKPAETFESGIRKTVEWYLNNEKWWSRVLDGSYSRERLGTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWQ7</accession>
    <name>D0YWQ7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">UDP-sugar hydrolase</fullName>
            <ecNumber evidence="5">3.1.3.5</ecNumber>
            <ecNumber evidence="5">3.6.1.45</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001453</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the 5'-nucleotidase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.5" evidence="5"/>
    <dbReference type="EC" id="3.6.1.45" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001453"/>
    <dbReference type="EnsemblBacteria" id="EEZ40427">
        <property type="protein sequence ID" value="EEZ40427"/>
        <property type="gene ID" value="VDA_001453"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0737">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110165">
        <property type="term" value="C:cellular anatomical entity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008768">
        <property type="term" value="F:UDP-sugar diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106411">
        <property type="term" value="F:XMP 5'-nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009166">
        <property type="term" value="P:nucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008334">
        <property type="entry name" value="5'-Nucleotdase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036907">
        <property type="entry name" value="5'-Nucleotdase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006146">
        <property type="entry name" value="5'-Nucleotdase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006179">
        <property type="entry name" value="5_nucleotidase/apyrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575">
        <property type="entry name" value="PTHR11575"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02872">
        <property type="entry name" value="5_nucleotid_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01607">
        <property type="entry name" value="APYRASEFAMLY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55816">
        <property type="entry name" value="SSF55816"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00786">
        <property type="entry name" value="5_NUCLEOTIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="3">
        <location>
            <begin position="6"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="5_nucleotid_C" evidence="4">
        <location>
            <begin position="309"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="495" mass="54506" checksum="E3FE7D53A42E899D" modified="2010-01-19" version="1">MAARKTLLDKLRAEIKAEGGTSLLLSGGDINTGVPESDLQDAEPDFKGMNLLGYDAMALGNHEFDNPLDVLRKQEAWANFPMLSANIYDKKTGKRLFQPYQIFTQQGLKIAVIGLTTEDTAKIGNPEYIGEIEFRDPKVEAKKVIAELKKTENPDIIIAATHMGHYEDGKRGVNAPGDVALARFLPSGELDMIVGGHSQEPVCMEAKNVSDKNYQPGEKCTPDQQNGTWIVQAHEWGKYVGRADFEFKNGELNMVSYDLIPVNLKKKVTLADGSKQRVFIQPEIAQNQEVLKFLTPYQDKGQEQLNIKIAESNGKLEGDRNVVRFEQTNLGRLIAAAHMERAKADFAVMNSGGVRDSIPAGNITYKDVLTVQPFGNIVTYVDMTGNEVLDYLNVVATKPVDSGAYAQFYGVSMVVENNKVHDVKIGGKALNPTATYRFTIPSFNAAGGDGYPKIADHAGYVNTGFVDAEVLKEYLHKHSPIDVNKFAPKGEIVYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWT4</accession>
    <name>D0YWT4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Formate acetyltransferase</fullName>
            <ecNumber evidence="8">2.3.1.54</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Pyruvate formate-lyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">VDA_001479</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>acetyl-CoA + formate = CoA + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:11844"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.1.54"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Fermentation; pyruvate fermentation; formate from pyruvate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.54" evidence="8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298130.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001479"/>
    <dbReference type="EnsemblBacteria" id="EEZ40453">
        <property type="protein sequence ID" value="EEZ40453"/>
        <property type="gene ID" value="VDA_001479"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1882">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="116406at2"/>
    <dbReference type="UniPathway" id="UPA00920">
        <property type="reaction ID" value="UER00891"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008861">
        <property type="term" value="F:formate C-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01678">
        <property type="entry name" value="PFL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005949">
        <property type="entry name" value="Form_AcTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019777">
        <property type="entry name" value="Form_AcTrfase_GR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001150">
        <property type="entry name" value="Gly_radical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004184">
        <property type="entry name" value="PFL_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01228">
        <property type="entry name" value="Gly_radical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02901">
        <property type="entry name" value="PFL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01255">
        <property type="entry name" value="pyr_form_ly_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00850">
        <property type="entry name" value="GLY_RADICAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51149">
        <property type="entry name" value="GLY_RADICAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51554">
        <property type="entry name" value="PFL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8 11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0313">Glucose metabolism</keyword>
    <keyword evidence="11" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 7 8" id="KW-0556">Organic radical</keyword>
    <keyword evidence="11" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PFL" evidence="10">
        <location>
            <begin position="1"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="domain" description="Glycine radical" evidence="9">
        <location>
            <begin position="629"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="modified residue" description="Glycine radical" evidence="7">
        <location>
            <position position="732"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU368075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ40453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="757" mass="84187" checksum="1CE379592EFCD564" modified="2010-01-19" version="1">MAEQFAAWEGFTAGDWQNEVNVRDFIQKNYTPYEGDGSFLETEATPATAKLWDAVMEGIKQENATHAPVDFDTDVISTITAHDAGYINKELETIVGLQTDAPLKRGLIPNGGIRMIEGSCKVYGRELNADIKKIYSEYRKTHNQGVFDIYTPDILKCRKSGVLTGLPDAYGRGRIIGDYRRVALYGIDALMKDKLAQFTSLQERFEKGEDLQMTMQLREEICEQHRALGQIKAMAAKYGCDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSLGRTSTFLDIFIERDIAAGKITEAQAQEMIDHFVMKLRMVRFLRTPEYDELFSGDPIWATESMGGMGLDGRTLVTRTNFRFLNSLYTMGPSPEPNITVLWSEQLPVGFKKFCAKVSIDTSSIQYENDDLMRPDMNSDDYAIACCVSPMVVGKQMQFFGARANLAKTMLYSINGGVDEKLKMQVGPKTDPVTSEVLDYTDVMDRLDHFMDWLATQYVTALNAIHYSHDKYSYEASLMALHDRDVKRTMACGIAGLSVAADSLSAIKYATVKPIRDEDGIAIDFEIEGDYPKFGNNDARVDDIACDLVERFMNKIRTHKMYRDAIPTQSILTITSNVVYGKKTGNTPDGRRAGAPFAPGANPMHGRDEKGAVASLTSVGKLPFAHAKDGISYTFSIVPNALGKDLDTQETNLAGLMDGYFHHEAGIEGGQHLNVNVLNRETLEDAVKHPEKYPQLTIRVSGYAVRFNSLTPEQQRDVISRTFTASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWX5</accession>
    <name>D0YWX5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Peptide transport system ATP-binding protein SapD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_001808</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298742.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001808"/>
    <dbReference type="EnsemblBacteria" id="EEZ40776">
        <property type="protein sequence ID" value="EEZ40776"/>
        <property type="gene ID" value="VDA_001808"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4172">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1101128at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01727">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="4"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="40"/>
            <end position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="332" mass="37391" checksum="7091E3CAE2350CA6" modified="2010-01-19" version="1">MPLLDIRNLTIEIDTPQGRVKAVDRMSMTINESEIRGLVGESGSGKSLVAKAIAGVAKDNWHITADRMRLGDIDLLALSSRERRKIVGREMAMIFQEASSCLDPSERVGAQLEEAIPSSAFSGHLWQRFHWRQKQAIALLHKVGIKDHKRVMRSYSYELTDGECQKVMIAMAIANRPRLLIADEPTNDLDSITQAQIFRLLSRMNQLGNTTILLISHDLTTVTQWADRITVMYCGQSVESGSRQDLLETPHHPYTEALLRAMPDFSDGICHKSKLETLPGSIPPLQHLPIGCRLGPRCPHAQRKCVEVPERRKVKSHKYSCHFPLNMEKDKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWY3</accession>
    <name>D0YWY3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001816</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298760.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001816"/>
    <dbReference type="EnsemblBacteria" id="EEZ40784">
        <property type="protein sequence ID" value="EEZ40784"/>
        <property type="gene ID" value="VDA_001816"/>
    </dbReference>
    <dbReference type="GeneID" id="57342069"/>
    <dbReference type="eggNOG" id="COG3106">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="929462at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007413">
        <property type="entry name" value="DUF463_YcjX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38605">
        <property type="entry name" value="PTHR38605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04317">
        <property type="entry name" value="DUF463"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019381">
        <property type="entry name" value="YcjX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="464" mass="53322" checksum="1A6C996E010E5950" modified="2010-01-19" version="1">MNRLGNEFNKWVNRGLDRHVRLAVTGLSRAGKTAFITSLVNQLLHVSTNPRLPLFTPVREGHLLGAKRVPQLDMHIPKFGYDEGMASILSTPPAWPEPTRDVSQIRLALRYRPQKGALKYLQDTATLYLDIVDYPGEWLLDLPLLDMDFMTWSKQQALVLKGKRLELAQEWMALGDEFDPFAPVDEALLEKISQAFTQYLYACKDEGGLHWVQPGRFVLPGELAGAPVLQFFPMIWTNKYTEQQLQEADEHSNFAMLKQRYKYYQQHIVKGFYKEHFSKFDRQIILVDCLQPLNAGPESFNDMRQAIDQLMQSFKYGRSSLLRRMFAPRIDKVLFAATKADHVTPEQHPNLVNLLQQLVNEAWHTASFEGIEMDCVSLASIQATEPGFVNHHGQQVPALRGVSMDEQPQTLFPGEVPKRLPNESFWQNNGFEFMNFRPLEQQSDEPLPHIRMDKALEFLLGDKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWZ9</accession>
    <name>D0YWZ9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Prophage LambdaW5 minor tail protein Z putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002052</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299286.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41020">
        <property type="protein sequence ID" value="EEZ41020"/>
        <property type="gene ID" value="VDA_002052"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG50314P9">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1697048at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="171" mass="19555" checksum="DA3A95919B730F11" modified="2010-01-19" version="1">MTSLNSNMVLDTRFLERLSHLPDELSKAAKRSLVKTNQWLRAVSMADLGYELTIDSKAMATRFRVYKSGATSKLWVGVRKIGVHRLGSPVQTDSGVKVAGHFFPHAFIAPMDSDKLLVFRRQNKARKSIQMVTLDISQESEEIIDSYLPDLNRKFEEFFHREFNYILSGSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX34</accession>
    <name>D0YX34_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">23S rRNA (uracil(747)-C(5))-methyltransferase RlmC</fullName>
            <ecNumber evidence="4">2.1.1.189</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">23S rRNA(m5U747)-methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rlmC</name>
        <name evidence="7" type="ORF">VDA_001890</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>S-adenosyl-L-methionine + uridine(747) in 23S rRNA = 5-methyluridine(747) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42628"/>
            <dbReference type="Rhea" id="RHEA-COMP:10154"/>
            <dbReference type="Rhea" id="RHEA-COMP:10155"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74447"/>
            <dbReference type="EC" id="2.1.1.189"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmC subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.189" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298883.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001890"/>
    <dbReference type="EnsemblBacteria" id="EEZ40858">
        <property type="protein sequence ID" value="EEZ40858"/>
        <property type="gene ID" value="VDA_001890"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2265">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1421660at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070041">
        <property type="term" value="F:rRNA (uridine-C5-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01012">
        <property type="entry name" value="23SrRNA_methyltr_RlmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011825">
        <property type="entry name" value="23SrRNA_MeTrfase_RlmC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030390">
        <property type="entry name" value="MeTrfase_TrmA_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010280">
        <property type="entry name" value="U5_MeTrfase_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11061">
        <property type="entry name" value="PTHR11061"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05958">
        <property type="entry name" value="tRNA_U5-meth_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02085">
        <property type="entry name" value="meth_trns_rumB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51687">
        <property type="entry name" value="SAM_MT_RNA_M5U"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01230">
        <property type="entry name" value="TRMA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 4 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="3 4 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4 5" id="KW-0808">Transferase</keyword>
    <feature type="active site" evidence="6">
        <location>
            <position position="337"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4 5">
        <location>
            <position position="337"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="3"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="11"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="215"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="244"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="265"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="310"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="379" mass="42452" checksum="687A2BFF9E6EE41A" modified="2010-01-19" version="1">MHCSLSASNLCRSCPLSSLSYDQQIEKKDQGLRSLLAPCQPQHWLEPVRSATQGYRNKAKMVVLGAAHEPCLGAVAVVDEDNKPISLRACPLYPQDMQDLLAALEQWIRTSGIPPYNVNKKKGELKFILLTRSHKAGEFMIRFVLRSHNAMPRIEANLERLMTAFPAIKVVSVNIQPVHMARLEGDEEIFLTQAQHLDEQLNDVPLVIRPKSFFQTNPDVAAKLYATARQWVREIKPSAMWDLFCGVGGFALHCVSPETDVTGIEIEPEAIASAQRSAQAMGITNLDFAALDSTGFSMEHDTAPELVLVNPPRRGIGEQLCQQLSYFAPKHIIYSSCNPETLAIDIQRLEGYELEKVQWFDMFPHTDHAEVLVLLSHKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX46</accession>
    <name>D0YX46_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hypothetical membrane-fusion protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001840</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001840"/>
    <dbReference type="EnsemblBacteria" id="EEZ40808">
        <property type="protein sequence ID" value="EEZ40808"/>
        <property type="gene ID" value="VDA_001840"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0845">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HlyD_D23" evidence="3">
        <location>
            <begin position="86"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="111"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="372" mass="41351" checksum="91D517F492A0B4BA" modified="2010-01-19" version="1">MDYVCHLSVFDTTTKQGKTNHRDWRVFMGHRMSVTLLSCMVLAGCGEKAKEIPEPESRPVKLLSVSIGDNQSFRTFPATVAAGDKAVLAFRVPGQLQHVFAHPGDVVKRGQKLAQLNVDELSLQVRQAKANYQLKKVQFDRNAQLRKTNVVSELDFDASKSALKQAKATLDKAKANLAYATLKAPYNGNVSLSLVENYEYVGAKQPVMHIQSAGLINVTFQLPDHLLTRFQSTTDDITPAVTFDTIKDQTYQAKFKEIDTESDPKTSSYKVTLYMDRPEGKNILPGMSGQVRLAIPKGESGSVPKRALMTEGDEVYVWHIDEQGLAHKVKVQLDEQQHIISGLNDGDQIATSGVKELQEGQKVRPWIKERGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXD7</accession>
    <name>D0YXD7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ion-translocating oxidoreductase complex subunit G</fullName>
            <ecNumber evidence="8">7.-.-.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Rnf electron transport complex subunit G</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rnfG</name>
        <name evidence="10" type="ORF">VDA_001616</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="8">The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell inner membrane</location>
            <topology evidence="8">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the RnfG family.</text>
    </comment>
    <dbReference type="EC" id="7.-.-.-" evidence="8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298383.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001616"/>
    <dbReference type="EnsemblBacteria" id="EEZ40589">
        <property type="protein sequence ID" value="EEZ40589"/>
        <property type="gene ID" value="VDA_001616"/>
    </dbReference>
    <dbReference type="GeneID" id="57342306"/>
    <dbReference type="eggNOG" id="COG4659">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1381933at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00479">
        <property type="entry name" value="RsxG_RnfG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007329">
        <property type="entry name" value="FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010209">
        <property type="entry name" value="Ion_transpt_RnfG/RsxG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36118">
        <property type="entry name" value="PTHR36118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04205">
        <property type="entry name" value="FMN_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006091">
        <property type="entry name" value="E_trnsport_RnfG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00900">
        <property type="entry name" value="FMN_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01947">
        <property type="entry name" value="rnfG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0249">Electron transport</keyword>
    <keyword evidence="3 8" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4 8" id="KW-0288">FMN</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 8" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-1278">Translocase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 8" id="KW-0813">Transport</keyword>
    <feature type="domain" description="FMN_bind" evidence="9">
        <location>
            <begin position="101"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="modified residue" description="FMN phosphoryl threonine" evidence="8">
        <location>
            <position position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ40589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="210" mass="22745" checksum="5AF45C6575C59AED" modified="2010-01-19" version="1">MFQAMKKNGGILALFALLATGLVAITHLLTEGRIAKQQEIELMDILNQVVPAQSHDNVLYKSCTLVKDLPRLGTNDAEPAYIATKDGKPVGIAIQAIAPDGYSGAIKLIVGLNMDGVVTGVRVLQQNETPGLGDKIETSVSNWIYSFNGKKVKGENDPAWHVRKDGGEFDQFTGATITPRAVVKSVKNVSLFWDQNKEKILNQPLNCSGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXD8</accession>
    <name>D0YXD8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Ion-translocating oxidoreductase complex subunit D</fullName>
            <ecNumber evidence="10">7.-.-.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Rnf electron transport complex subunit D</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">rnfD</name>
        <name evidence="11" type="ORF">VDA_001617</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="10">The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell inner membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the NqrB/RnfD family.</text>
    </comment>
    <dbReference type="EC" id="7.-.-.-" evidence="10"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001617"/>
    <dbReference type="EnsemblBacteria" id="EEZ40590">
        <property type="protein sequence ID" value="EEZ40590"/>
        <property type="gene ID" value="VDA_001617"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4658">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022900">
        <property type="term" value="P:electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00462">
        <property type="entry name" value="RsxD_RnfD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004338">
        <property type="entry name" value="NqrB/RnfD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011303">
        <property type="entry name" value="RnfD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30578">
        <property type="entry name" value="PTHR30578"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30578:SF0">
        <property type="entry name" value="PTHR30578:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03116">
        <property type="entry name" value="NQR2_RnfD_RnfE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01946">
        <property type="entry name" value="rnfD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="3 10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4 10" id="KW-0288">FMN</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 10" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="18"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="94"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="124"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="213"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="240"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="266"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="297"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="322"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="modified residue" description="FMN phosphoryl threonine" evidence="10">
        <location>
            <position position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ40590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="349" mass="37804" checksum="633639E19718C5C7" modified="2010-01-19" version="1">MFNIASSPHAHSRKSTSAIMRTVILCAAFGIAAQTYFFGIGTLIQVLLASTVSVLAEACVLKLRKRPIVPYLRDNSALLTGVLIGISIPPLAPWWLTVIGVIFAIVIAKHLYGGLGQNLFNPAMVAYVVLLISFPVQMTTWLPPSSLSANPTSMLDSIMAIFTGFTQDGYSVQQLRLSIDGVTMATPLDTFKTSLTTGMHAVDIMAKPVYDSFAGIGWEWVNLGFLLGGLILLKMRIIQWYIPVSMLLGLFIASSIGYVVDPAQHASPLIHMFSGATMLGAFFIATDPITASTTVKGRLIFGAFIGVMTYLIRTHGGFPDGVAFSVLLANMCVPLIDYYTRPRTYGHTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXF0</accession>
    <name>D0YXF0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Molybdopterin synthase sulfur carrier subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001629</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the MoaD family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298404.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001629"/>
    <dbReference type="EnsemblBacteria" id="EEZ40602">
        <property type="protein sequence ID" value="EEZ40602"/>
        <property type="gene ID" value="VDA_001629"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1977">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1995573at2"/>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010038">
        <property type="entry name" value="MoaD_arc-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044672">
        <property type="entry name" value="MOCS2A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016155">
        <property type="entry name" value="Mopterin_synth/thiamin_S_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003749">
        <property type="entry name" value="ThiS/MoaD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33359">
        <property type="entry name" value="PTHR33359"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02597">
        <property type="entry name" value="ThiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54285">
        <property type="entry name" value="SSF54285"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01687">
        <property type="entry name" value="moaD_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="81" mass="8861" checksum="6825FDE131C8DCB7" modified="2010-01-19" version="1">MITVLFFAQVKELVGQSQIDVEASVNTAEELRQQLTLRGDKWQLALESGKLLVAVNQTICPLDTEIKDGDEVAFFPPVTGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXF6</accession>
    <name>D0YXF6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Oligopeptide transport ATP-binding protein OppD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_001635</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298415.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001635"/>
    <dbReference type="EnsemblBacteria" id="EEZ40608">
        <property type="protein sequence ID" value="EEZ40608"/>
        <property type="gene ID" value="VDA_001635"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0444">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1101128at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01727">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="6"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="40"/>
            <end position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="323" mass="35939" checksum="6FBE201073BE6DA9" modified="2010-01-19" version="1">MSLLDVKDLRVEFTTQDGIVTAVNDLNFSLNQGETLGIVGESGSGKSQTVFAIMGLLAKNGKISGRAEFEGRNILNLPERELNKIRAEQIAMIFQDPMTSLNPYMKVSDQLMEVLMLHKGMSKQQAFEESVRMLDAVKIPEARNRMTMYPHEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMELLNDLKQDFNTSIIMITHDLGVVAGSCDKVLVMYAGRTMEYGKINEIFYQPGHPYTEGLLKAIPRLDTEGEMLPTIPGNPPNLLNLPVGCPYQERCHRVSARCHQEAPILTPFADGRLRACFAEMEVASC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXG8</accession>
    <name>D0YXG8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 8">Corrinoid adenosyltransferase</fullName>
            <ecNumber evidence="5 8">2.5.1.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Cob(II)alamin adenosyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Cob(II)yrinic acid a,c-diamide adenosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_001673</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 8">
            <text>2 ATP + 2 cob(II)alamin + reduced [electron-transfer flavoprotein] = 2 adenosylcob(III)alamin + 3 H(+) + oxidized [electron-transfer flavoprotein] + 2 triphosphate</text>
            <dbReference type="Rhea" id="RHEA:28671"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16304"/>
            <dbReference type="ChEBI" id="CHEBI:18036"/>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="EC" id="2.5.1.17"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>2 ATP + 2 cob(II)yrinate a,c diamide + reduced [electron-transfer flavoprotein] = 2 adenosylcob(III)yrinate a,c-diamide + 3 H(+) + oxidized [electron-transfer flavoprotein] + 2 triphosphate</text>
            <dbReference type="Rhea" id="RHEA:11528"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18036"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="ChEBI" id="CHEBI:58503"/>
            <dbReference type="ChEBI" id="CHEBI:58537"/>
            <dbReference type="EC" id="2.5.1.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 8">Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 2/7.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 8">Belongs to the Cob(I)alamin adenosyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.17" evidence="5 8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298493.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001673"/>
    <dbReference type="EnsemblBacteria" id="EEZ40646">
        <property type="protein sequence ID" value="EEZ40646"/>
        <property type="gene ID" value="VDA_001673"/>
    </dbReference>
    <dbReference type="GeneID" id="57342245"/>
    <dbReference type="eggNOG" id="COG2109">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1690483at2"/>
    <dbReference type="UniPathway" id="UPA00148">
        <property type="reaction ID" value="UER00233"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008817">
        <property type="term" value="F:cob(I)yrinic acid a,c-diamide adenosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006779">
        <property type="term" value="P:porphyrin-containing compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00561">
        <property type="entry name" value="CobA_CobO_BtuR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003724">
        <property type="entry name" value="CblAdoTrfase_CobA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025826">
        <property type="entry name" value="Co_AT_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12557">
        <property type="entry name" value="Co_AT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02572">
        <property type="entry name" value="CobA_CobO_BtuR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015617">
        <property type="entry name" value="Adensltrnsf_CobA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00708">
        <property type="entry name" value="cobA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Co_AT_N" evidence="9">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR015617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ40646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="201" mass="22457" checksum="80AD9BE364DCDC04" modified="2010-01-19" version="1">MTSNSDKNQRYKDRQQKVKQHIDAKVEAAQQEKGLLLIITGNGKGKSTSGFGTVARAVGHGYRCGVGQFIKGTWDCGERNLLEQHGVTFAVMATGFTWETQNKEADTLAAQQTWQACKKMLADPSYDVVLLDELTYMITYHYIDLDELIEALNNRPPMQSVIITGRGAHRSLIELADTVSEVRNIKHAFENGIKARQGVDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXH7</accession>
    <name>D0YXH7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">3-oxoacyl-[acyl-carrier-protein] synthase 3</fullName>
            <ecNumber evidence="8">2.3.1.180</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">3-oxoacyl-[acyl-carrier-protein] synthase III</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Beta-ketoacyl-ACP synthase III</fullName>
            <shortName evidence="8">KAS III</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">fabH</name>
        <name evidence="11" type="ORF">VDA_001684</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>acetyl-CoA + H(+) + malonyl-[ACP] = 3-oxobutanoyl-[ACP] + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:12080"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9625"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:78450"/>
            <dbReference type="EC" id="2.3.1.180"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the thiolase-like superfamily. FabH family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.180" evidence="8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298510.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001684"/>
    <dbReference type="EnsemblBacteria" id="EEZ40655">
        <property type="protein sequence ID" value="EEZ40655"/>
        <property type="gene ID" value="VDA_001684"/>
    </dbReference>
    <dbReference type="GeneID" id="57342235"/>
    <dbReference type="eggNOG" id="COG0332">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="872193at2"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033818">
        <property type="term" value="F:beta-ketoacyl-acyl-carrier-protein synthase III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01815">
        <property type="entry name" value="FabH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013751">
        <property type="entry name" value="ACP_syn_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013747">
        <property type="entry name" value="ACP_syn_III_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004655">
        <property type="entry name" value="FabH_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08545">
        <property type="entry name" value="ACP_syn_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08541">
        <property type="entry name" value="ACP_syn_III_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00747">
        <property type="entry name" value="fabH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="4 8" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 8" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5 8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACP_syn_III" evidence="10">
        <location>
            <begin position="106"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="ACP_syn_III_C" evidence="9">
        <location>
            <begin position="229"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="ACP-binding" evidence="8">
        <location>
            <begin position="246"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="112"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="245"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ40655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="318" mass="33912" checksum="4B72894FAE3E6C2C" modified="2010-01-19" version="1">MYSKILGTGSYLPAQVRTNADLEQMVETNDEWIVARTGIRERRIANTEETVAVMGYQASLNAIDMAGIAKEDIDLIIMATSSASHSFPSAACQVQGMLDIKGCPAFDLSAACSGFMYALSIADQHIKTGMAKNVLVIGADALSHKCDPTDRSTIILFGDAAGAVVVGASEEPGILSTHIHADGHFGGLLSLGIPEHGEDFSDDNWLYMAGNEVFKVAVTQLSNLVKDTLAANNMDKSELDWLVPHQANLRIISATAKKLSMSLDQVVVTLDRHGNTSAATVPTALDEAVRDGRIQRGQTLLLEAFGGGFTWGSALVKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXN3</accession>
    <name>D0YXN3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative thiosulfate sulfur transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001730</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298592.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001730"/>
    <dbReference type="EnsemblBacteria" id="EEZ40700">
        <property type="protein sequence ID" value="EEZ40700"/>
        <property type="gene ID" value="VDA_001730"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2897">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1385159at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004792">
        <property type="term" value="F:thiosulfate sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001307">
        <property type="entry name" value="Thiosulphate_STrfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045078">
        <property type="entry name" value="TST/MPST-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11364">
        <property type="entry name" value="PTHR11364"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00380">
        <property type="entry name" value="RHODANESE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018662" evidence="2">
        <location>
            <begin position="22"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodanese" evidence="3">
        <location>
            <begin position="34"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodanese" evidence="3">
        <location>
            <begin position="163"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodanese" evidence="3">
        <location>
            <begin position="304"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="434" mass="48747" checksum="F1FAA67F9F1CB786" modified="2010-01-19" version="1">MRVSNTYFPLLGLVLSCSASAATFAEYQQIQQQSPNQVQIIDCRDSNFYNGWPQNTMKSGGHVPGAISLDANWLNQTSPHALSNLMMSKHISNKKQTFLYCGEKKAQSLANALKSQGIDNIKIITQPIDQYHGTLSALPQFQHLVPAWWLNDLIKGKDPLYTPKNGYKVVEVAWGPPAKYLLAHIPGAYYLNTNDIESEPWWNRVSPKQLKQVINDLGLRYDTTVILYGRDNTAAARAANILMYAGVKDVRLLNGGWQSWVDAGYCSEPMLNENHDKVDFGKPIPANPNYIIDVPQAKALLKQPKDQQSLVSIRSWAEYTGETSGYSYIKPKGRIPGSKWGHAGSDPYHLEDLRNPDGTMRSPNEIAQLWQQWDIKPNQDVAFYCGTGWRASEAFFDAYLMGWKNISVFDGGWYQWSGDKSNPTAHGDIKPSKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXU0</accession>
    <name>D0YXU0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Universal stress protein E</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002103</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299441.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002103"/>
    <dbReference type="EnsemblBacteria" id="EEZ41071">
        <property type="protein sequence ID" value="EEZ41071"/>
        <property type="gene ID" value="VDA_002103"/>
    </dbReference>
    <dbReference type="GeneID" id="57341769"/>
    <dbReference type="eggNOG" id="COG0589">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2040681at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="1">
        <location>
            <begin position="4"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="Usp" evidence="1">
        <location>
            <begin position="176"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="313" mass="35191" checksum="9795E6C249547CB0" modified="2010-01-19" version="1">MKKYKNILVVADPNQDYQPALVRAAYLAKHSENAKITLFLAIYDFSYEMTSMLSADERIAMRRGVVMQREEWLKEIIKPYESDSYEIAISVVWHNRPYEAVIAEVFSQDIELLIKATHNHDTLGSVIFTPTDWHLLRKCPCPVLLVKDQEWQPNGKVLACVNLAADNETHEELNDNIIDEANRFAHVLEAEVNLVNAYPSTPVNITIELPEFDPASYTDAVRGHHLTSMKALRQKYGIDEAQTHVLEGLPEDIIPRVAEDLGVEMVVLGTTGRTGLSAVFIGNTAEHTIDRLNCDLLALKPTGYISPLAPNIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY77</accession>
    <name>D0YY77_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002240</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002240"/>
    <dbReference type="EnsemblBacteria" id="EEZ41208">
        <property type="protein sequence ID" value="EEZ41208"/>
        <property type="gene ID" value="VDA_002240"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1357">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="215" mass="24791" checksum="19EF9DE00EA14721" modified="2010-01-19" version="1">MEQMHFEREDFSQQDLAGQIYRHCRFILCDFSRANLTDTQFIDCCFIESGDSQGCDFAYAQLKDASFKGCNLSFANFRGAQCFGLELRETNLQGADFQQASFTNYISHNTYFCSAYISACNLSYCNFEDVKFEECELFENRWNGANLLGVSFVGSDLSRGEFSQEQWRQCVWHKVNLTHVDLDGVDIRYVDFTGVQICDWQQEQLLNQLGIVVLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY96</accession>
    <name>D0YY96_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Hypothetical phosphatase/phosphohexomutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002259</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299744.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002259"/>
    <dbReference type="EnsemblBacteria" id="EEZ41227">
        <property type="protein sequence ID" value="EEZ41227"/>
        <property type="gene ID" value="VDA_002259"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0637">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1167152at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00413">
        <property type="entry name" value="HADHALOGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="226" mass="24871" checksum="19055AFEDFE5CF2F" modified="2010-01-19" version="1">MQAICFDFDGTLVDSEVFHAANWSLYMASHDVELSADVFMHKYAGVTWPNIAKILIEKFQLNIEPQQIVDDMEALTEEQIRAKGIPAKEGAETLLKQLTGKVPLAVVTGAPRIYVEGILAQKGWLEWFDVIFTGDDVEHNKPAPDIYQLACQHFELPTESVIAVEDSTTGATSALTAGLKTIFVNTINLPISGQAARHFSDLIEAQPTICAMLSLDCDKNNKQHVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYD2</accession>
    <name>D0YYD2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ATP-dependent dethiobiotin synthetase BioD</fullName>
            <ecNumber evidence="5">6.3.3.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">DTB synthetase</fullName>
            <shortName evidence="5">DTBS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Dethiobiotin synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">bioD</name>
        <name evidence="6" type="ORF">VDA_002295</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>(7R,8S)-7,8-diammoniononanoate + ATP + CO2 = (4R,5S)-dethiobiotin + ADP + 3 H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:15805"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:149469"/>
            <dbReference type="ChEBI" id="CHEBI:149473"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.3.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; biotin biosynthesis; biotin from 7,8-diaminononanoate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the dethiobiotin synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.3.3.3" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299809.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002295"/>
    <dbReference type="EnsemblBacteria" id="EEZ41263">
        <property type="protein sequence ID" value="EEZ41263"/>
        <property type="gene ID" value="VDA_002295"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0132">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1739932at2"/>
    <dbReference type="UniPathway" id="UPA00078">
        <property type="reaction ID" value="UER00161"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004141">
        <property type="term" value="F:dethiobiotin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009102">
        <property type="term" value="P:biotin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00336">
        <property type="entry name" value="BioD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004472">
        <property type="entry name" value="DTB_synth_BioD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43210">
        <property type="entry name" value="PTHR43210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006755">
        <property type="entry name" value="DTB_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00347">
        <property type="entry name" value="bioD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5" id="KW-0093">Biotin biosynthesis</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="5">
        <location>
            <position position="38"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="13"/>
            <end position="18"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="17"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="116"/>
            <end position="119"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="176"/>
            <end position="177"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="227" mass="24964" checksum="0667524DE4725522" modified="2010-01-19" version="1">MTKAFFVTGTDTEVGKTVATRAILHAAGHADIKMSGYKPVASGSSRTEGGLRNSDALYIQEASVVELSYQEVNPYAFEEPVSPHLAAEREKRTIEFEVLTQGLDNLKQKSDVVLVEGAGGWRVPVAREQFLSQWVQQQKMPVILVVGVKLGCLSHAMLTAEAIERDGLEVVGWIANRINPGEENYAENIQMLEAQLPGKKLGEIPYMPGIKKRNLAQYIDLSVLELI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYE3</accession>
    <name>D0YYE3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mlc transcriptional repressor of MalT (The transcriptional activator of maltose regulon) and manXYZ operon</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002306</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ROK (NagC/XylR) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299830.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002306"/>
    <dbReference type="EnsemblBacteria" id="EEZ41274">
        <property type="protein sequence ID" value="EEZ41274"/>
        <property type="gene ID" value="VDA_002306"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1940">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1130699at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01125">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="404" mass="44287" checksum="744D3BD545FE0EDE" modified="2010-01-19" version="1">MYVAQPGHIDHIKRNNAGSVYKLIDLYGPISRIELSKRSQLAPASITKITRELIDAHLIKETQYQESTSRGRPAIGLIPNNEGWQFLSIRIGRGYLTIALHELGGDILVEERQEISELHQDDLIEKLLGEINIFFARHVSELDRITAIAVSLPGLVNAKEGMVLQMPHYDVKNLPLGPVIHQATGLPVFIGNDTRSWALAEKLFGHSQGVANSLLISIHHGVGAGIVLDDSVLQGSIGNVGELGHIQIKPFGRRCFCGNHGCLETVASLQAVLEQTEQCLRDGHPSSLHGGKVTIERICDAAVEGDALARQIISELGHNLGQAIAIMVNLFNPQRILIGGEFNRAKSVLYPAIMECVRTQSIPLYNRDLDIMESCFYTQATMPGAALVKQAMYDGHLLMKLIEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYF1</accession>
    <name>D0YYF1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Enoyl-CoA hydratase</fullName>
            <ecNumber evidence="1">4.2.1.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002314</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="4.2.1.17" evidence="1"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299845.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002314"/>
    <dbReference type="EnsemblBacteria" id="EEZ41282">
        <property type="protein sequence ID" value="EEZ41282"/>
        <property type="gene ID" value="VDA_002314"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1024">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1498685at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004300">
        <property type="term" value="F:enoyl-CoA hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="252" mass="28554" checksum="2F4742E66BB00B7A" modified="2010-01-19" version="1">MDIQLSIDNGIAQLTLDRPQTYNALTLNMYQELGRHFIELTNNPEVKIIILTSSSDFFCSGNDMFDFRTIGHCSEQEIQKHRLDIESFMFNFINCSKPIIAAVTGPAIGIGTTLLQYCDYVVASSHSYFQTPFTALGLCPEFGASVVLEKLIGARKARAMLLFSEKMTASEASELRFINAISAKPIKHSYEIAGQLQHLSINAITHSKRMLKNIQYHNIEETIKQENDLIFQLIQQPDAQARIEKFIEKSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYK2</accession>
    <name>D0YYK2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative two-component response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_002365</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299963.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002365"/>
    <dbReference type="EnsemblBacteria" id="EEZ41333">
        <property type="protein sequence ID" value="EEZ41333"/>
        <property type="gene ID" value="VDA_002365"/>
    </dbReference>
    <dbReference type="GeneID" id="57341435"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1020672at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="2"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="125"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="125"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="222" mass="25225" checksum="4166BD899E8183E8" modified="2010-01-19" version="1">MKVLIVDDNHNIAETIADYLELEGMTIDCAYHGEAALNLVKENHYDVIIMDIMMPKLDGINAVKKLREEQFCNTPILFLTAKDQLEDKIAAFKAGGDDYLLKPFAMEELCLRLYALSNRGPRQDIGELKFADITINTRTDEVKRAETEIKLSRIQLKILKLLMRQAPSIVSRQEVIESIWGDETPSSDALRSHIYGLRNALDKGFETSRLETIHGQGYRIKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYV1</accession>
    <name>D0YYV1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Probable membrane transporter protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_002464</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300143.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002464"/>
    <dbReference type="EnsemblBacteria" id="EEZ41432">
        <property type="protein sequence ID" value="EEZ41432"/>
        <property type="gene ID" value="VDA_002464"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0730">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1746903at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002781">
        <property type="entry name" value="TM_pro_TauE-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01925">
        <property type="entry name" value="TauE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="38"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="94"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="132"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="170"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="206"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="235"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="263"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="297" mass="31539" checksum="17C1243CE133FD3A" modified="2010-01-19" version="1">MSIFTLIQAGLLVGGAIFVFLLIQAWRRNRTQEAQTKIVPIGLIGGFANFCDTLGIGSFAIMTAGYKQFKLVDDKVLPGTLNCQSVLATVVQSLIFLTAVNVDAVTLVSLVIAACAGATVGAKLVSSWDRQLIRIVMSMALLIVAGLMLAGQLKLFPLGGTALGLTGWKLAIGIAGNFLFGALMTVGIGLYAPCMTMIYMLGMNPLAAFPVMMCSCAFLSFFSAGGFLVRDRVNTRAALVVAITGPIAVVIAAYLVKSLDMHLLAWLVTGVVLYTAISMYRSWSQDRKSTPEPIANL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYV3</accession>
    <name>D0YYV3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 11">ATP phosphoribosyltransferase</fullName>
            <shortName evidence="11">ATP-PRT</shortName>
            <shortName evidence="11">ATP-PRTase</shortName>
            <ecNumber evidence="4 11">2.4.2.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">hisG</name>
        <name evidence="14" type="ORF">VDA_002466</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10 11">Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>1-(5-phospho-beta-D-ribosyl)-ATP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + ATP</text>
            <dbReference type="Rhea" id="RHEA:18473"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:73183"/>
            <dbReference type="EC" id="2.4.2.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="11">Feedback inhibited by histidine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the ATP phosphoribosyltransferase family. Long subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.17" evidence="4 11"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300147.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002466"/>
    <dbReference type="EnsemblBacteria" id="EEZ41434">
        <property type="protein sequence ID" value="EEZ41434"/>
        <property type="gene ID" value="VDA_002466"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0040">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1419568at2"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00006"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003879">
        <property type="term" value="F:ATP phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00079">
        <property type="entry name" value="HisG_Long"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013820">
        <property type="entry name" value="ATP_PRibTrfase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018198">
        <property type="entry name" value="ATP_PRibTrfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001348">
        <property type="entry name" value="ATP_PRibTrfase_HisG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020621">
        <property type="entry name" value="ATP_PRibTrfase_HisG_long"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013115">
        <property type="entry name" value="HisG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21403">
        <property type="entry name" value="PTHR21403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01634">
        <property type="entry name" value="HisG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08029">
        <property type="entry name" value="HisG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="SSF54913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00070">
        <property type="entry name" value="hisG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03455">
        <property type="entry name" value="HisG_C-term"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01316">
        <property type="entry name" value="ATP_P_PHORIBOSYLTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 11 14" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 11" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HisG" evidence="12">
        <location>
            <begin position="53"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="HisG_C" evidence="13">
        <location>
            <begin position="222"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEZ41434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="298" mass="33175" checksum="3A8B43C9619AD13A" modified="2010-01-19" version="1">MQTPRLRIAIQKKGRLSKECQNLLKQCGVKFNMVGERLVVHAENMPIDLLLVRDDDIPGLIMDGVVDLGVIGENELEEVGLERIARNEPADYKKLRRLDFGGCRLSIAIDKDAKYNGPQDLQGKRIATTYPQLVKRYMDERGVKFSTCMLNGSVEVAPRAGLADAICDLVSTGATLEANGLKEVEVILRSKAALIQAKIPMSAEKQALIDRLLTRMQGVIQAKESKYIMLHAPTDRLDQIKQLLPGAEDPTVMPLSQDRTKVAIHLVSSENLFWETMEQLKELGASSILVLPIEKMME</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYV8</accession>
    <name>D0YYV8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 10">1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase</fullName>
            <ecNumber evidence="8 10">5.3.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">hisA</name>
        <name evidence="11" type="ORF">VDA_002471</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8 10">
            <text>1-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamide = 5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:15469"/>
            <dbReference type="ChEBI" id="CHEBI:58435"/>
            <dbReference type="ChEBI" id="CHEBI:58525"/>
            <dbReference type="EC" id="5.3.1.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 8 10">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 4/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 8 10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 8 9">Belongs to the HisA/HisF family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.16" evidence="8 10"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300156.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002471"/>
    <dbReference type="EnsemblBacteria" id="EEZ41439">
        <property type="protein sequence ID" value="EEZ41439"/>
        <property type="gene ID" value="VDA_002471"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0106">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="794219at2"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00009"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003949">
        <property type="term" value="F:1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04732">
        <property type="entry name" value="HisA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01014">
        <property type="entry name" value="HisA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006062">
        <property type="entry name" value="His_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006063">
        <property type="entry name" value="HisA_bact_arch"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044524">
        <property type="entry name" value="Isoase_HisA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023016">
        <property type="entry name" value="Isoase_HisA-like_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43090">
        <property type="entry name" value="PTHR43090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00977">
        <property type="entry name" value="His_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00007">
        <property type="entry name" value="TIGR00007"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8 9" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="7 8 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="7"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ41439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="245" mass="26461" checksum="1F9D0142F017D7CE" modified="2010-01-19" version="1">MIIPALDLIDGQVVRLYQGDYGQVTEYKVNPSEQFALYYRAGAQWLHLVDLTGAKNTQARQLDLIASILASTPANIQIGGGVRHLEDVKALLSAGAKRVVIGSTAVKHPQQVKQWIQELGADKIVLALDININDQGERHVAVSGWQEDSGVTIEALLEDYLTVGLQHVLCTDISRDGTLQGSNVALYQDLCRNYPTIAFQSSGGIGSLNDIAALKNSGVAGVIVGRALLDGHFTAEDAFQLWARE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYW0</accession>
    <name>D0YYW0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Histidine biosynthesis bifunctional protein HisIE</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="13">Phosphoribosyl-AMP cyclohydrolase</fullName>
                <shortName evidence="13">PRA-CH</shortName>
                <ecNumber evidence="13">3.5.4.19</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="13">Phosphoribosyl-ATP pyrophosphatase</fullName>
                <shortName evidence="13">PRA-PH</shortName>
                <ecNumber evidence="13">3.6.1.31</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="13" type="primary">hisI</name>
        <name evidence="13" type="synonym">hisIE</name>
        <name evidence="15" type="ORF">VDA_002473</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>1-(5-phospho-beta-D-ribosyl)-5'-AMP + H2O = 1-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:20049"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58435"/>
            <dbReference type="ChEBI" id="CHEBI:59457"/>
            <dbReference type="EC" id="3.5.4.19"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 13">
            <text>1-(5-phospho-beta-D-ribosyl)-ATP + H2O = 1-(5-phospho-beta-D-ribosyl)-5'-AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22828"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:59457"/>
            <dbReference type="ChEBI" id="CHEBI:73183"/>
            <dbReference type="EC" id="3.6.1.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4 13">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/9.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 13">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 3/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 13">In the C-terminal section; belongs to the PRA-PH family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 13">In the N-terminal section; belongs to the PRA-CH family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.19" evidence="13"/>
    <dbReference type="EC" id="3.6.1.31" evidence="13"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300161.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002473"/>
    <dbReference type="EnsemblBacteria" id="EEZ41441">
        <property type="protein sequence ID" value="EEZ41441"/>
        <property type="gene ID" value="VDA_002473"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0139">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0140">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1842189at2"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00007"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004635">
        <property type="term" value="F:phosphoribosyl-AMP cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004636">
        <property type="term" value="F:phosphoribosyl-ATP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd11534">
        <property type="entry name" value="NTP-PPase_HisIE_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.810">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01020">
        <property type="entry name" value="HisE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01019">
        <property type="entry name" value="HisIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023019">
        <property type="entry name" value="His_synth_HisIE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008179">
        <property type="entry name" value="HisE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021130">
        <property type="entry name" value="PRib-ATP_PPHydrolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002496">
        <property type="entry name" value="PRib_AMP_CycHydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038019">
        <property type="entry name" value="PRib_AMP_CycHydrolase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01502">
        <property type="entry name" value="PRA-CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01503">
        <property type="entry name" value="PRA-PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141734">
        <property type="entry name" value="SSF141734"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03188">
        <property type="entry name" value="histidine_hisI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11 13" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="9 13 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12 13" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="8 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PRA-CH" evidence="14">
        <location>
            <begin position="30"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphoribosyl-AMP cyclohydrolase" evidence="13">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphoribosyl-ATP pyrophosphohydrolase" evidence="13">
        <location>
            <begin position="117"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00008299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEZ41441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="206" mass="22953" checksum="77EA1056924F3D82" modified="2010-01-19" version="1">MSLITEINWEKVGGLIPVIVQDSRTQKVLMLGYMNDAALSSTLDTHKVTFWSRTKQRLWMKGESSGNILKLEEIKLDCDQDTLLIQAIPVGPTCHRNTETCFDDKDIKLSAASPLFLQQLEQVLASRKGADPKSSYTASLYARGTKRISQKVGEEGVEVALAATSGDKEELICESADLLYHLLVLLQDQGLSLQDVLNKLHQRHNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYX0</accession>
    <name>D0YYX0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hypothetical hydrolase/acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002483</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300178.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002483"/>
    <dbReference type="EnsemblBacteria" id="EEZ41451">
        <property type="protein sequence ID" value="EEZ41451"/>
        <property type="gene ID" value="VDA_002483"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1498437at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="39"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="300" mass="34208" checksum="5F1CD66C65944B6E" modified="2010-01-19" version="1">MVFDIQFQLAELQLAGFCSFEFDKTNGSKNSSVAKTDAPLILMFHGWQDNAATFIPLIQHLRPYYQMIAVDLPGHGLSHHRSTDNFYHFVDYLDDISQLVEQLSSTEQPIILLGHSLGAIIANSIGAMMPEHIQAVIAIEGLTPLFESESNTLKRLQKGVASRKLSRRRLQREPKGFLSFSEALAMRAKANQLKPELLEQVVERGCYLDQQDWFWRHDPKLRCESLFRMSSNQVKNIIEGIECPVFSIVGEHGFDYLRAPQTSHSWFRNLEQVQVKGGHHCHLESSEAVAYYVKEFISKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYX9</accession>
    <name>D0YYX9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Ferrous iron transport protein B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">VDA_002492</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Probable transporter of a GTP-driven Fe(2+) uptake system.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell inner membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300195.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002492"/>
    <dbReference type="EnsemblBacteria" id="EEZ41460">
        <property type="protein sequence ID" value="EEZ41460"/>
        <property type="gene ID" value="VDA_002492"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0370">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="304844at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015093">
        <property type="term" value="F:ferrous iron transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055072">
        <property type="term" value="P:iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01879">
        <property type="entry name" value="FeoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003373">
        <property type="entry name" value="Fe2_transport_prot-B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011640">
        <property type="entry name" value="Fe2_transport_prot_B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041069">
        <property type="entry name" value="FeoB_Cyto"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030389">
        <property type="entry name" value="G_FEOB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011642">
        <property type="entry name" value="Gate_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07664">
        <property type="entry name" value="FeoB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17910">
        <property type="entry name" value="FeoB_Cyto"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02421">
        <property type="entry name" value="FeoB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07670">
        <property type="entry name" value="Gate"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00437">
        <property type="entry name" value="feoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51711">
        <property type="entry name" value="G_FEOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 10" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="4 10" id="KW-0410">Iron transport</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="282"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="333"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="421"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="452"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="510"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="666"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="694"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="726"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="domain" description="FeoB-type G" evidence="11">
        <location>
            <begin position="2"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ41460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="758" mass="82967" checksum="FABA4E90928996AD" modified="2010-01-19" version="1">MQYHILTVGNPNSGKTTLFNGLTGAKQHVGNWAGVTVEKKTGRYERVGDEFVLTDLPGIYNLDSANDANSLDEAIASRAILTTPADVIINVVDASCLERSLYMTLQLRELGRPMIVVLNKMDVLKRQRQILDIKGLEKALGCPVLSLSANNKKQVEEFKEKLHKMLTQGISVHGLSLDYGVEFESAVSELEPLFSDGEVKARAQAIRVLENDTLVINTLEDDDKFKACNTRSKLMVDVDPDIQVADIRYTFLHNLCQKVRRQEGKLSHNITERIDNVLLNRLFGIPFFFIVMYLMFLFAINVGSAFIDFFDISFGAIFVDGAHHVLDGHLPAWLVTVIANGVGGGIQTVATFIPVIACLYLFLTVLESSGYMARAAFVLDKVMQKIGLPGKAFVPLVLGFGCNVPAIMATRTLEHERERKLAAAMAPFMSCGARLPVYALFAAAFFPHSGQNVVFSLYILGIVVAIFTGLVLRNTLYPGTSDSFIMEMPDYELPTFRNVVLKTWQKVKKFVLGAGKTIVVVVAILSFFNSLGVDGSFGNEDSPNSVLSKTAQVVTPVLEPIGVKADNWPATVGIITGIFAKEAVVGTLNSLYSPEQAGDDTEYDLLGSLKEAVESIPANLEGINFSDPLGLSVGDLDNQSAAAEEQGVDQSVFGNIQAHFVSSAAAMAYLIFILLYTPCAAAMGAYAREFGQKFAWFIAGWTMLLAYTCATLFYQIAHFMDHPASSMLWIGLFVAINVGLILIFKHQGKKQREELLAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ42</accession>
    <name>D0YZ42_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hypothetical lipoprotein-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002555</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300316.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002555"/>
    <dbReference type="EnsemblBacteria" id="EEZ41523">
        <property type="protein sequence ID" value="EEZ41523"/>
        <property type="gene ID" value="VDA_002555"/>
    </dbReference>
    <dbReference type="GeneID" id="57341204"/>
    <dbReference type="eggNOG" id="COG3126">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1992770at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039366">
        <property type="entry name" value="Pilotin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09619">
        <property type="entry name" value="YscW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019860" evidence="1">
        <location>
            <begin position="20"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="140" mass="15286" checksum="FB9AC2EE1326966F" modified="2010-01-19" version="1">MKKAFMMVSTLAAALVVTACTKLIPTDTNMGHIQGNVTYRERIALPDDAKVTVTLEDVSLADAPAEVLSRQTFLTDGKQPPFAYQLSYQSDQIEPNHRYIVSARIEGQNGKLLFVSDTAYPVLTNAAKTATQDILVINAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ51</accession>
    <name>D0YZ51_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Enoyl-CoA hydratase/delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase</fullName>
            <ecNumber evidence="14">1.1.1.35</ecNumber>
            <ecNumber evidence="14">4.2.1.17</ecNumber>
            <ecNumber evidence="14">5.1.2.3</ecNumber>
            <ecNumber evidence="14">5.3.3.8</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">VDA_002564</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a (3S)-3-hydroxyacyl-CoA + NAD(+) = a 3-oxoacyl-CoA + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:22432"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57318"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
            <dbReference type="EC" id="1.1.1.35"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism; fatty acid beta-oxidation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.35" evidence="14"/>
    <dbReference type="EC" id="4.2.1.17" evidence="14"/>
    <dbReference type="EC" id="5.1.2.3" evidence="14"/>
    <dbReference type="EC" id="5.3.3.8" evidence="14"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300339.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002564"/>
    <dbReference type="EnsemblBacteria" id="EEZ41532">
        <property type="protein sequence ID" value="EEZ41532"/>
        <property type="gene ID" value="VDA_002564"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1024">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1250">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="977512at2"/>
    <dbReference type="UniPathway" id="UPA00659"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003857">
        <property type="term" value="F:3-hydroxyacyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008692">
        <property type="term" value="F:3-hydroxybutyryl-CoA epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004165">
        <property type="term" value="F:delta(3)-delta(2)-enoyl-CoA isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004300">
        <property type="term" value="F:enoyl-CoA hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006180">
        <property type="entry name" value="3-OHacyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006176">
        <property type="entry name" value="3-OHacyl-CoA_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006108">
        <property type="entry name" value="3HC_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012802">
        <property type="entry name" value="FadJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00725">
        <property type="entry name" value="3HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02737">
        <property type="entry name" value="3HCDH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02440">
        <property type="entry name" value="FadJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00067">
        <property type="entry name" value="3HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="14" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="6 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3HCDH_N" evidence="13">
        <location>
            <begin position="309"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="domain" description="3HCDH" evidence="12">
        <location>
            <begin position="497"/>
            <end position="590"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEZ41532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="706" mass="77321" checksum="CBA5C4345F93132C" modified="2010-01-19" version="1">MNNSAFTLTIDDDKLAWLKIDVPNEKMNTLQDCFATEISQVLEQLEASSDIKGMVIYSGKPDNFVAGADIKMLAACETAEQAQQLATTGQELFTRLENLPFHVVAAIHGPCLGGGLELALACHSRVATLDDKTRIGLPEVQLGLLPGSGGTQRLPRLIGVANALDMILTGKQLRAKKAKKMGVVDAVVDSEILLTVAKEIALEHKPKRQSSWQNWAMGGNPLGRSVVFDQAKKKTEQKTRGNYPATTAILEVIKHGLDKGLSQGYALEAQRFGELVMSSQSKALRHIFFATTAMKKEQGSLEQAHPLTHIGVLGGGLMGAGISHVTATKADLPVRIKDVHNDGVLNALNYNYKLFSKKRDRKIISKAQLQNQMSMFTGGTDFIGYNQLDMVVEAVFEDLALKHQMVRDIETHSKPDTIFATNTSSLPIHQIASAAQRPEQVVGLHYFSPVEKMPLVEIIPHQGTELGGATSQQTIETAITLAKKQGKTPIVVADTAGFYVNRILAPYMNEAARLLLEGEPIEHIDRSLLDFGFPVGPITLLDEVGVDIGAKISPILLAELGERFQAPDLFDTLLNDGRKGRKSGKGFYLYNGKKKEADKQVYQLLNLEPEQHLAGQDLALRCTLMMLNEAVRCLDEGVIQSARDGDIGAIFGIGFPPFLGGPFHYMDSLGLDRVLDMFIDYSHKYGERFAPCEGIVMRAENKQSFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ70</accession>
    <name>D0YZ70_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein-glutamate methylesterase/protein-glutamine glutaminase</fullName>
            <ecNumber evidence="4">3.1.1.61</ecNumber>
            <ecNumber evidence="4">3.5.1.44</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">cheB</name>
        <name evidence="10" type="ORF">VDA_002583</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>H2O + L-glutaminyl-[protein] = L-glutamyl-[protein] + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:16441"/>
            <dbReference type="Rhea" id="RHEA-COMP:10207"/>
            <dbReference type="Rhea" id="RHEA-COMP:10208"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29973"/>
            <dbReference type="ChEBI" id="CHEBI:30011"/>
            <dbReference type="EC" id="3.5.1.44"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>[protein]-L-glutamate 5-O-methyl ester + H2O = H(+) + L-glutamyl-[protein] + methanol</text>
            <dbReference type="Rhea" id="RHEA:23236"/>
            <dbReference type="Rhea" id="RHEA-COMP:10208"/>
            <dbReference type="Rhea" id="RHEA-COMP:10311"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17790"/>
            <dbReference type="ChEBI" id="CHEBI:29973"/>
            <dbReference type="ChEBI" id="CHEBI:82795"/>
            <dbReference type="EC" id="3.1.1.61"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="4">Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.</text>
    </comment>
    <comment type="PTM">
        <text evidence="4">Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the CheB family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.61" evidence="4"/>
    <dbReference type="EC" id="3.5.1.44" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300393.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002583"/>
    <dbReference type="EnsemblBacteria" id="EEZ41551">
        <property type="protein sequence ID" value="EEZ41551"/>
        <property type="gene ID" value="VDA_002583"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2201">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1655418at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000156">
        <property type="term" value="F:phosphorelay response regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008984">
        <property type="term" value="F:protein-glutamate methylesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050568">
        <property type="term" value="F:protein-glutamine glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018277">
        <property type="term" value="P:protein deamination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006482">
        <property type="term" value="P:protein demethylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16432">
        <property type="entry name" value="CheB_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00099">
        <property type="entry name" value="CheB_chemtxs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008248">
        <property type="entry name" value="CheB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035909">
        <property type="entry name" value="CheB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000673">
        <property type="entry name" value="Sig_transdc_resp-reg_Me-estase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01339">
        <property type="entry name" value="CheB_methylest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52738">
        <property type="entry name" value="SSF52738"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50122">
        <property type="entry name" value="CHEB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 5" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="8">
        <location>
            <begin position="4"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="CheB-type methylesterase" evidence="9">
        <location>
            <begin position="224"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="146"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="active site" evidence="4 5">
        <location>
            <position position="236"/>
        </location>
    </feature>
    <feature type="active site" evidence="4 5">
        <location>
            <position position="263"/>
        </location>
    </feature>
    <feature type="active site" evidence="4 5">
        <location>
            <position position="359"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="4 6">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ41551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="417" mass="44966" checksum="C4618003FAA49C8D" modified="2010-01-19" version="1">MAIKVLVVDDSSFFRRRVSEIISADPKLEVIGSAANGKEAIAQTRQLHPDVITMDIEMPVMDGITAVREIMKVAPTPILMFSSLTHEGAKATLDALDAGALDFLPKKFEDIARNREEAVSLLQKRIVELSHKRRFMRRPVSSTLTSGLVHTSRTSATTRLSDTARSHISSSALSTSHSNLRTTKPTVAATASANSARVQVAKPHITEHSVPVSANKPMMRFKASGKKYQLVAIGTSTGGPVALQKILTKLPARFPLPIVLIQHMPSTFTPAFAARLDNLCKISVKEAQDGDILQPGKAYLAPGGMQMMVDGRVGAGRLRILDGGERMNYKPCVDVTFGSAAKVYQDKVLSIILTGMGADGREGARMLKANGSTIWAQDEESCVVYGMPQAVAKAGISSEDLPLDRIAERILVELGLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZB9</accession>
    <name>D0YZB9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 9">Cell division protein ZipA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">zipA</name>
        <name evidence="13" type="ORF">VDA_002632</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 9">Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Interacts with FtsZ via their C-terminal domains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell inner membrane</location>
            <topology evidence="8">Single-pass type I membrane protein</topology>
        </subcellularLocation>
        <text evidence="8">Localizes to the Z ring in an FtsZ-dependent manner.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8 9">Belongs to the ZipA family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300548.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002632"/>
    <dbReference type="EnsemblBacteria" id="EEZ41600">
        <property type="protein sequence ID" value="EEZ41600"/>
        <property type="gene ID" value="VDA_002632"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3115">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1632200at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090529">
        <property type="term" value="P:cell septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043093">
        <property type="term" value="P:FtsZ-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1400.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00509">
        <property type="entry name" value="ZipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011919">
        <property type="entry name" value="Cell_div_ZipA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007449">
        <property type="entry name" value="ZipA_FtsZ-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036765">
        <property type="entry name" value="ZipA_FtsZ-bd_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38685">
        <property type="entry name" value="PTHR38685"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04354">
        <property type="entry name" value="ZipA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00771">
        <property type="entry name" value="ZipA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64383">
        <property type="entry name" value="SSF64383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02205">
        <property type="entry name" value="septum_zipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 8 9" id="KW-0132">Cell division</keyword>
    <keyword evidence="2 8 10" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1 8 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="domain" description="ZipA_C" evidence="12">
        <location>
            <begin position="280"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="31"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="66"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ41600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="417" mass="45384" checksum="84CFECD956446D51" modified="2010-01-19" version="1">MQELRLVLIIFGALIIAALLLHGLWTSKKEKPAKFGEKPQSKLNESVVEPKVETPKVVQESVETPVVKESKTKKAERKEPELHFGAKPEADPLLGDIAPISADDDLPKMSAVDEPKAAVQPQAIVEPVAQTVVSEPAQAQAQAQAQAQAQAQAQAQAQAQAQAVEPTIEAPVSVPEPTMTAEPVVHTPVAEPIAAEMITPVVETTVTPVIETPVTATEPQVEPRHEELVEEVVTPAEVSQPVPEIKQPEVKVEPEFVEPEPYEIIEPVIAEPEPEPAPLEPSYISLCVHARSGGVLMGRQLFTALENHGLIFGENSVYHRHLDRAGTQPVIFSVTNLVAPGNFPDINDAHFETPGIGFFLMLPCPGRADDNFNTMLQTAQRIADDLNADVLDHERNMITPYRITAYRDKAKLYANAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZD9</accession>
    <name>D0YZD9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aminoacyl-histidine dipeptidase (Peptidase D)</fullName>
            <ecNumber evidence="3">3.4.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002652</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.4.13.3" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300607.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002652"/>
    <dbReference type="MEROPS" id="M20.007"/>
    <dbReference type="EnsemblBacteria" id="EEZ41620">
        <property type="protein sequence ID" value="EEZ41620"/>
        <property type="gene ID" value="VDA_002652"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2195">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1015417at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016805">
        <property type="term" value="F:dipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03890">
        <property type="entry name" value="M20_pepD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001160">
        <property type="entry name" value="Peptidase_M20C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43501">
        <property type="entry name" value="PTHR43501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016599">
        <property type="entry name" value="Xaa-His_dipept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00934">
        <property type="entry name" value="XHISDIPTASE"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01893">
        <property type="entry name" value="aa-his-dipept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0224">Dipeptidase</keyword>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="2">
        <location>
            <begin position="209"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="486" mass="52667" checksum="B1F347A5CE3A180A" modified="2010-01-19" version="1">MSEISQLSPKALWQFFDKICSIPHPSKYEEQLAQYIVSFAQQEGLDVRRDNVGNVIIKKPATPGMEDRKGVVLQAHIDMVPQKNEDTAHDFLVDPIQPYVDGEWVTAKGTTLGADNGIGMATCLAVLAAKDIEHGPLEVLLTIDEEAGMTGAFGLEAGWLEGDILLNTDSEQEGEVYMGCAGGVDGAITVEIAREATPSELVGAKLVIKGLKGGHSGCDIHTGRGNANKLLGRFLFGHAQELGLRLESITGGSLRNAIPREANAVVALPAANLDKLNELFSHYQDLLNAELGHVETDINLFIETQEQPAQIMALADQNRLVAVLNACPNGVIRMSDDIQGVVETSLNVGVITTEENKVTILCLIRSLIDSGRSNVEGMLKAVAELAGAGCEFAGAYPGWKPDADSEIMHLFRDTYNNMYGRTPNIMVIHAGLECGLFKKPYPTMDMLSFGPTIKFPHSPDEKVNIETVALFWDQMVAILKNIPVKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZF1</accession>
    <name>D0YZF1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="2">PPIase</shortName>
            <ecNumber evidence="2">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_002664</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300644.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002664"/>
    <dbReference type="EnsemblBacteria" id="EEZ41632">
        <property type="protein sequence ID" value="EEZ41632"/>
        <property type="gene ID" value="VDA_002664"/>
    </dbReference>
    <dbReference type="GeneID" id="57341069"/>
    <dbReference type="eggNOG" id="COG0652">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1861282at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000413">
        <property type="term" value="P:protein peptidyl-prolyl isomerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044665">
        <property type="entry name" value="E_coli_cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43246">
        <property type="entry name" value="PTHR43246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="SSF50891"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0697">Rotamase</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006523347" description="Peptidyl-prolyl cis-trans isomerase" evidence="2">
        <location>
            <begin position="19"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="3">
        <location>
            <begin position="26"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="183" mass="19909" checksum="6A61A6D54B4303CF" modified="2010-01-19" version="1">MKRFFIALCLMIALPVSAATKVLVTTNLGNFTIELNEQKAPISSANFLKYVKDGSYVGTIFHRVIPGFMAQGGGFDENMKQRPSYAAIINEATNGLKNDTATVAMARTSNPNSATRQFYINYANNDFLNASANNPGYAVFGKVVDGFSVVKKMAEIPTTTIPTMGMKDVPQQPIVIKAMKVIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZI3</accession>
    <name>D0YZI3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002696</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41664">
        <property type="protein sequence ID" value="EEZ41664"/>
        <property type="gene ID" value="VDA_002696"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3133">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2003802at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="157" mass="16082" checksum="B2256ADBC3013C84" modified="2010-01-19" version="1">MASSLIIGLTGCQATGEQYKATSYQVSALNHKQEAKTINIIAVTAAQVQVDNSQAKKTTTAVGSLLGSVAGAFIGDNQGETLVGGLLGGVAGGATGLVVSDTIMVEGVTLTYSEKNKIFTSTQIGRSCEFKPGVALVVSTEKNETRVQPNSVCVEQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZJ6</accession>
    <name>D0YZJ6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Chaperone protein HscA homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">hscA</name>
        <name evidence="7" type="ORF">VDA_002709</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002709"/>
    <dbReference type="EnsemblBacteria" id="EEZ41677">
        <property type="protein sequence ID" value="EEZ41677"/>
        <property type="gene ID" value="VDA_002709"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0443">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10236">
        <property type="entry name" value="HscA_like_NBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00679">
        <property type="entry name" value="HscA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042039">
        <property type="entry name" value="HscA_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010236">
        <property type="entry name" value="ISC_FeS_clus_asmbl_HscA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="PTHR19375"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="SSF100920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="SSF100934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01991">
        <property type="entry name" value="HscA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="592" mass="63433" checksum="772F729DE7CF1954" modified="2010-01-19" version="1">MGTTNSLVAAVRSGVPEALSDEQGRTILPSVVHFGLEDTLVGHEARAIAQQDPTNTIVSVKRLMGRSLADIEQRYPQLPYEFEASENGLPLLKTCVGKINPIQVSAEILKSLADRATKTLGGDLEGVVITVPAYFDDAQRAGTKDAAKLANLNVLRLLNEPTAAAIAYGLDSGQEGVIAVYDLGGGTFDISILRLSKGVFEVLATGGDSALGGDDFDHLIAEWILSQAGIEQALTASERRALQDISQAAKEALTDSDSTDVTFLGWQGQLTREQFDELARPLVKKTLMSCRRALKDADISSEDVLETVMVGGSTRVPIVREMVGDYFGKTPLTSIDPDKVVAIGAAIQADILAGNKPDSEMLLLDVIPLSLGIETMGGLVEKIIPRNTTIPVARAQEFTTFKDGQTAMSVHVVQGEREMVSDCRSLARFTLRGIPAMAAGAAHIRVTYQVDADGLLSVTAMEKSSGVQSTIQVKPSYGLTDDEIATMISDSMTYAQDDKDARALAEQRVEADRVLEGLIAALAADGETLLSKEERDALEAVMMELVQLRQGEDARAIEAGIKKTDKASQDFAARRMDQSIRRALAGQSIDEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0D3</accession>
    <name>D0Z0D3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Translocation and assembly module subunit TamA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Autotransporter assembly factor TamA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">VDA_002996</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell outer membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TamA family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301508.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002996"/>
    <dbReference type="EnsemblBacteria" id="EEZ41964">
        <property type="protein sequence ID" value="EEZ41964"/>
        <property type="gene ID" value="VDA_002996"/>
    </dbReference>
    <dbReference type="GeneID" id="57340691"/>
    <dbReference type="eggNOG" id="COG0729">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="470487at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000184">
        <property type="entry name" value="Bac_surfAg_D15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039910">
        <property type="entry name" value="D15-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035243">
        <property type="entry name" value="TamA_POTRA_Dom_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12815">
        <property type="entry name" value="PTHR12815"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01103">
        <property type="entry name" value="Omp85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17243">
        <property type="entry name" value="POTRA_TamA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1134">Transmembrane beta strand</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019932" description="Translocation and assembly module subunit TamA" evidence="8">
        <location>
            <begin position="24"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="domain" description="POTRA_TamA_1" evidence="10">
        <location>
            <begin position="27"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="Omp85" evidence="9">
        <location>
            <begin position="266"/>
            <end position="570"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00033063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF17243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ41964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="573" mass="63777" checksum="BF78370636924811" modified="2010-01-19" version="1">MKKFFKPLSLTAFALAFSTAAHASSSLKIKGLDGKLESNVEAYLSGIPKEDYSATLRFQEQVEDEVKQALQALGYYQPSIDYRAKPDGDEIDITITVDAGTATHIAKSDIEITGAAANDPDFLALIRNSGLSIGDQLNHGNYEAFKSSLSSLALKKGYFDAEMTKSVMEVAPSRAEAFIIIHFDSGKRYNFGQTLFQGSQIDQDRLDSLIPYQENEPYLASKLGLFNERLSSVGWFSSIFVGGDVNERKGDEIPIHVALSPAVRNKVEVGMGYSTDVGYNFKLNWKKPWINSKGHSLTVKSEFSKVQPKIEAAYKIPLDDVLNNYYQVIGGIRYVDNHDTRSTEYSAGLERHWKLESGWKRVASLRWLYEDYKQGEFESGVAHMLIPGLTYSRTRTRGGAMPTWGDRQMFSVEVTDPALGSDNRLARLRGQTAWIRSLSENQRGLFRLDAGAVFTDHLATVPPSMRFFAGGDNSIRGYGYESVGPRDSAGKLLGGKYMATSSLEYQYRVYGDWWGAIFYDYGSAWNDSPDWVSGAGVGVRWASPVGPVTLDFAWGLDKEKDKFQLHFSLGPEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0E8</accession>
    <name>D0Z0E8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Sulfite reductase [NADPH] flavoprotein alpha-component</fullName>
            <shortName evidence="10">SiR-FP</shortName>
            <ecNumber evidence="10">1.8.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">VDA_003012</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -&gt; FAD -&gt; FMN to the hemoprotein component.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>3 H2O + hydrogen sulfide + 3 NADP(+) = 4 H(+) + 3 NADPH + sulfite</text>
            <dbReference type="Rhea" id="RHEA:13801"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17359"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.8.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10 11">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="10 11">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10 11">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
        <text evidence="10 11">Binds 1 FMN per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="10">Sulfur metabolism; hydrogen sulfide biosynthesis; hydrogen sulfide from sulfite (NADPH route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.2" evidence="10"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301561.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003012"/>
    <dbReference type="EnsemblBacteria" id="EEZ41979">
        <property type="protein sequence ID" value="EEZ41979"/>
        <property type="gene ID" value="VDA_003012"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0369">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="707164at2"/>
    <dbReference type="UniPathway" id="UPA00140">
        <property type="reaction ID" value="UER00207"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004783">
        <property type="term" value="F:sulfite reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019344">
        <property type="term" value="P:cysteine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070814">
        <property type="term" value="P:hydrogen sulfide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.990.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010199">
        <property type="entry name" value="CysJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003097">
        <property type="entry name" value="CysJ-like_FAD-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001094">
        <property type="entry name" value="Flavdoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023173">
        <property type="entry name" value="NADPH_Cyt_P450_Rdtase_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00667">
        <property type="entry name" value="FAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000207">
        <property type="entry name" value="SiR-FP_CysJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00369">
        <property type="entry name" value="FLAVODOXIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01931">
        <property type="entry name" value="cysJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9 10" id="KW-0198">Cysteine biosynthesis</keyword>
    <keyword evidence="7 10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5 10 11" id="KW-0274">FAD</keyword>
    <keyword evidence="3 10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4 10 11" id="KW-0288">FMN</keyword>
    <keyword evidence="6 10 11" id="KW-0521">NADP</keyword>
    <keyword evidence="8 10 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 10" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="12">
        <location>
            <begin position="74"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="13">
        <location>
            <begin position="243"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="80"/>
            <end position="85"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="127"/>
            <end position="130"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="163"/>
            <end position="172"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="331"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="365"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="395"/>
            <end position="398"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="413"/>
            <end position="415"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="419"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="428"/>
            <end position="431"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="528"/>
            <end position="529"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="534"/>
            <end position="538"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="570"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="608"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR000207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000207-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEZ41979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="608" mass="67352" checksum="74C2450914368FBA" modified="2010-01-19" version="1">MISKEAANPLTALSPLNDQQLATLAQTAAELSPQQLAWISGYFWGLSQTPTVAAVAQATGDVSLNAHSNPAPKVTLIYASQTGNAKGVAQEVATFLNQHNIENQVVAAGDYKGKNLAKETYVVLVASTHGEGEAPDDAVELYEFMQSKKAPKLEPLNYAVIGLGDSSYEFFCQTGKDFDAFFKRLGAKAFVPRIDCDVDYSADISTWQGQALEQIQQALTTSAQVVPLPISHSSAQAINYSKQNPFTASLSVQQKITGRNSSKDVRHIEIDLEGSGLRYEPGDSLGIWYQNDPELVSQLLSTLGLDGETLVDVDGETLSLATALQHHYEITAANPLFVTKYAELSQSKRLLKLITNKDKLRQYAAETQIVDVIAEKKAQLTATELLSLLRRLTPRLYSIASSMSEVGEEVHLTVGVVQYQQKDQIRLGGASGFLAQRLAEDDAVKVFVETNNHFKLPENDSTPIIMVGPGTGIAPFRSFLQERDNREASGKNWLLFGDRSFTEDFLYQVEWQKYLKSGLLTQLDVAFSRDQVEKVYVQHRLLEHGKQVWQWLEDGAYFYVCGDASQMAKDVHQALLTLVQQHGNKNAEQAEQYLAELRKAKRYQKDVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0G7</accession>
    <name>D0Z0G7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein HflC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_003031</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">HflC and HflK could regulate a protease.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the band 7/mec-2 family. HflC subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301641.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003031"/>
    <dbReference type="MEROPS" id="I87.001"/>
    <dbReference type="EnsemblBacteria" id="EEZ41998">
        <property type="protein sequence ID" value="EEZ41998"/>
        <property type="gene ID" value="VDA_003031"/>
    </dbReference>
    <dbReference type="GeneID" id="57340513"/>
    <dbReference type="eggNOG" id="COG0330">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1714999at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052547">
        <property type="term" value="P:regulation of peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03405">
        <property type="entry name" value="SPFH_HflC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010200">
        <property type="entry name" value="HflC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42911">
        <property type="entry name" value="PTHR42911"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005651">
        <property type="entry name" value="HflC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="SSF117892"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01932">
        <property type="entry name" value="hflC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PHB" evidence="3">
        <location>
            <begin position="18"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR005651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="336" mass="38158" checksum="FB6210FFBD57D130" modified="2010-01-19" version="1">MRKLMIPVVVIFIALLLMSVFVVKEGERGIVVRFGRIIKDNNTEVAQVYAPGLHFKVPVFDRVHMLDARIQTMDDQADRFLTAEKKDVIIDTYVKWRIQNFGQYYLATGGGNISTAEALLKRKVVDSLRAEIGAKEIKQIVSGKDSAQPKAAKTDDANDQQTQIAEEIVKGLLPENDVKEVEGQRDQIMADVLSETRDSAKDLGIEVVDFRIKKINLPDEISESIYRRMRAERESVARSYRSQGRQRAEELRARAELKVATILAEANRKAQVLRGDADAQAADTYAEAYTKNPEFFSFWRSLKAYEKSFNSKNDVLVIDPDTEFFRYMNQANPKAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0S3</accession>
    <name>D0Z0S3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 3">Adenosine deaminase</fullName>
            <ecNumber evidence="1 3">3.5.4.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2 3">Adenosine aminohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">add</name>
        <name evidence="5" type="ORF">VDA_003137</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>2'-deoxyadenosine + H(+) + H2O = 2'-deoxyinosine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:28190"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17256"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:28997"/>
            <dbReference type="EC" id="3.5.4.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>adenosine + H(+) + H2O = inosine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:24408"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16335"/>
            <dbReference type="ChEBI" id="CHEBI:17596"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="3">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.4" evidence="1 3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301970.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003137"/>
    <dbReference type="EnsemblBacteria" id="EEZ42104">
        <property type="protein sequence ID" value="EEZ42104"/>
        <property type="gene ID" value="VDA_003137"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1816">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="554648at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046936">
        <property type="term" value="F:2'-deoxyadenosine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004000">
        <property type="term" value="F:adenosine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009168">
        <property type="term" value="P:purine ribonucleoside monophosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00540">
        <property type="entry name" value="A_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028893">
        <property type="entry name" value="A_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001365">
        <property type="entry name" value="A_deaminase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006330">
        <property type="entry name" value="Ado/ade_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11409">
        <property type="entry name" value="PTHR11409"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00962">
        <property type="entry name" value="A_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01430">
        <property type="entry name" value="aden_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="A_deaminase" evidence="4">
        <location>
            <begin position="7"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="200"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="12"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="14"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="16"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="278"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="279"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="3">
        <location>
            <position position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00031852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ42104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="334" mass="36289" checksum="7763ED8E9C2D5339" modified="2010-01-19" version="1">MITKHLPLTDLHRHLDGNIRVETILDLGQKFGLELPANSVESLRPHVQIVEAEPSLVAFLAKLDWGVAVLGDLDACRRVAYENVEDALRAQIDYAELRFSPYYMAMKHQLPIAGVVEAVADGVAAGCRDFGIKANLIGIMSRTFGTEACQQELDGLLAHKDKLVAIDLAGDELGQPGVQFIEHFKQVRNAGLNITIHAGEAAGPESMWQAITELGATRIGHGVKAIHDPKLMDYLAQNKIGIESCLTSNIQTSTVASYQTHPVKAFLEHGILACLNTDDPAVEGIELPYEYEVAAPKVGLTEAQIRQAQINGLELAFLSDSEKQALKTLAAQRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-08-12" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0W6</accession>
    <name>D0Z0W6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase</fullName>
            <ecNumber evidence="1">3.6.1.40</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Guanosine pentaphosphate phosphohydrolase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">pppGpp-5'-phosphohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">gppA</name>
        <name evidence="3" type="ORF">VDA_003180</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>guanosine 3'-diphosphate 5'-triphosphate + H2O = guanosine 3',5'-bis(diphosphate) + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13073"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:77828"/>
            <dbReference type="ChEBI" id="CHEBI:142410"/>
            <dbReference type="EC" id="3.6.1.40"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; ppGpp biosynthesis; ppGpp from GTP: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GppA/Ppx family. GppA subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.40" evidence="1"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302090.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003180"/>
    <dbReference type="EnsemblBacteria" id="EEZ42147">
        <property type="protein sequence ID" value="EEZ42147"/>
        <property type="gene ID" value="VDA_003180"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0248">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1862004at2"/>
    <dbReference type="UniPathway" id="UPA00908">
        <property type="reaction ID" value="UER00885"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008894">
        <property type="term" value="F:guanosine-5'-triphosphate,3'-diphosphate diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015974">
        <property type="term" value="P:guanosine pentaphosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015970">
        <property type="term" value="P:guanosine tetraphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01550">
        <property type="entry name" value="GppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023709">
        <property type="entry name" value="Guo-5TP_3DP_PyrP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003695">
        <property type="entry name" value="Ppx_GppA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030673">
        <property type="entry name" value="PyroPPase_GppA_Ppx"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02541">
        <property type="entry name" value="Ppx-GppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001267">
        <property type="entry name" value="Pyrophosphatase_GppA_Ppx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ppx-GppA" evidence="2">
        <location>
            <begin position="24"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ42147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="499" mass="55635" checksum="9AB222A01ACBC04F" modified="2010-01-19" version="1">MERSSTSPLYAAIDLGSNSFHMWVVREVDGHVQTLAKIKRKVRLAAGLNSNNELSLEAMQRGWDCLSLFAERLQDIPSEHVRIVGTAALRTAVNADEFLAKAKDILGYAIVVIPGKEEARIIYQGVAHTSGGSDKRLVVDIGGASTEVVIGTGFEANALTSLKIGCVTWLESYFKDRHLNAENFNAAISAAKMAIAPIVEQYRQLGWETCVGASGTVQALQEIMLAQGMDEIITLAKLKRLQRQAMQYERLEDLDIEGLTLERALVFPSGLSILIALFESLNIDSMTLAGGALREGMVYEMMSQMRHHDVRTRTLHSVQERFQLDTLHAEEVAKTAMTLLQDCDAEWQFEPQAQSLLFAAAQLHEIGISIEFKKSGEHAAYLINHLDLPGFTRAQKHLIAELLRRFREQLSSLPEQHALSAQSATRLLRLLRLAVILCHRRDQRCQADVQINATDNKLTLTLTKGWLTQNPLTEAELQQEATRQTDMGWPLTIETVENQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0Z3</accession>
    <name>D0Z0Z3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">PSDC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_003207</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302165.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003207"/>
    <dbReference type="EnsemblBacteria" id="EEZ42174">
        <property type="protein sequence ID" value="EEZ42174"/>
        <property type="gene ID" value="VDA_003207"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0688">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="891720at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004609">
        <property type="term" value="F:phosphatidylserine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003817">
        <property type="entry name" value="PS_Dcarbxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022237">
        <property type="entry name" value="PsiD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10067">
        <property type="entry name" value="PTHR10067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02666">
        <property type="entry name" value="PS_Dcarbxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12588">
        <property type="entry name" value="PSDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="1" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="7" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="8" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0865">Zymogen</keyword>
    <feature type="domain" description="PSDC" evidence="9">
        <location>
            <begin position="38"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ42174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="450" mass="50122" checksum="E35A450C57F98530" modified="2010-01-19" version="1">MTSANRTNTWLPQNRAHTQAWIQSLKSRTDFNAELVAPIAEFKQLVATNPVLASLAQEMFTEAKSHKDLTPLNGMAVSDFNEFLVLLNQIMTQAPEYTEYFDPKEGALEPYGLIGFPINALLDWPMATDAGNIFFANELVNQQLKKILSYWSQYLSSPESRSVLINDYPDRVPQVAGWLSADVKRKIIEVACQADPLDSEKRNQEFADFFNCDPSDTYYSFASWDDFFTRTFKPGVRPVAQGDGVIANACESAPLQVVKNVDKSAQFWLKGQPYSLENMMGFDPLAEQFVGGTIYQAFLSALSYHRWNSPVSGTVKKAYMLNGSYYLGNRYQGFCNPEGADDSAPNNSQPFLTAVATRAVIFIESDNPKIGLMCFIAVGMAEVSSCDITVLEGQHINKGDELGMFHFGGSTHCLIFRPEVELEFDFHNTTPGLDATNIPVCSRIATVKNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1E1</accession>
    <name>D0Z1E1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative lipopolysaccharide biosynthesis glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_003355</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302559.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003355"/>
    <dbReference type="EnsemblBacteria" id="EEZ42322">
        <property type="protein sequence ID" value="EEZ42322"/>
        <property type="gene ID" value="VDA_003355"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0463">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1379602at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="202"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="231"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="8"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ42322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="256" mass="29076" checksum="9753DB1DE79704B0" modified="2010-01-19" version="1">MEKKHTLSVILITKNEADRVEVCLRSVADIADEIIVLDSGSTDDTVEICRRYTDDITTTDWPGFGKQKQRALDKASCDWVLSIDADEALDDEMKQALIQLLSQQSIQETAYRLPWGVTLYGTTLKYGRSARSVLRLFKREGAKYTLDEVHETVIPATGDIGTLKGLLLHYTHRDYGHGLDKAAQYAWLGSQKYHRKGKKSHGLVLALLRAIWTFFHIYIIRRGFLDGSVGFIVAMTYAQVNFNKYVGLWLLENDRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1F4</accession>
    <name>D0Z1F4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Glycerol-3-phosphate dehydrogenase [NAD(P)+]</fullName>
            <ecNumber evidence="8">1.1.1.94</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_003368</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.94" evidence="8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003368"/>
    <dbReference type="EnsemblBacteria" id="EEZ42335">
        <property type="protein sequence ID" value="EEZ42335"/>
        <property type="gene ID" value="VDA_003368"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0240">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009331">
        <property type="term" value="C:glycerol-3-phosphate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004367">
        <property type="term" value="F:glycerol-3-phosphate dehydrogenase [NAD+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006072">
        <property type="term" value="P:glycerol-3-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006168">
        <property type="entry name" value="G3P_DH_NAD-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006109">
        <property type="entry name" value="G3P_DH_NAD-dep_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07479">
        <property type="entry name" value="NAD_Gly3P_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00077">
        <property type="entry name" value="GPDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00957">
        <property type="entry name" value="NAD_G3PDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="3 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="6" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD_Gly3P_dh_C" evidence="7">
        <location>
            <begin position="1"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ42335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="148" mass="15842" checksum="8C186EB25D18067E" modified="2010-01-19" version="1">MQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLAEMCRLGAALGAHPETFMGMAGLGDLVLTCTDNQSRNRRFGLALGKGESVEQAQIDIGQVVEGYRNTKEVHALAERFGVEMPITEQIYQVLYQGKDARIAAKDLLAREKKYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1N5</accession>
    <name>D0Z1N5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">50S ribosomal protein L14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rplN</name>
        <name evidence="6" type="ORF">VDA_003449</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 5">Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the universal ribosomal protein uL14 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302802.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003449"/>
    <dbReference type="EnsemblBacteria" id="EEZ42416">
        <property type="protein sequence ID" value="EEZ42416"/>
        <property type="gene ID" value="VDA_003449"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0093">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1799923at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.150.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01367">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036853">
        <property type="entry name" value="Ribosomal_L14_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000218">
        <property type="entry name" value="Ribosomal_L14P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005745">
        <property type="entry name" value="Ribosomal_L14P_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019972">
        <property type="entry name" value="Ribosomal_L14P_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11761">
        <property type="entry name" value="PTHR11761"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00238">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01374">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50193">
        <property type="entry name" value="SSF50193"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01067">
        <property type="entry name" value="rplN_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00049">
        <property type="entry name" value="RIBOSOMAL_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ42416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="123" mass="13645" checksum="8097210824694C6B" modified="2010-01-19" version="1">MIQMQSMLDAADNSGARSVMCIKVLGGSHRRYAQIGDIIKITVKEAIPRGKVKKGDVLKAVVVRTRKGVRRPDGSVIRFDRNACVLLNNNTEQPIGTRIFGPVTRELRTEKFMKIVSLAPEVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1T0</accession>
    <name>D0Z1T0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MSHA biogenesis protein MshL</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_003494</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303602.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003494"/>
    <dbReference type="EnsemblBacteria" id="EEZ42461">
        <property type="protein sequence ID" value="EEZ42461"/>
        <property type="gene ID" value="VDA_003494"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1450">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="870677at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009297">
        <property type="term" value="P:pilus assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001775">
        <property type="entry name" value="GspD/PilQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013358">
        <property type="entry name" value="Pilus_biogenesis_MshL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011662">
        <property type="entry name" value="Secretin/TonB_short_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011514">
        <property type="entry name" value="Secretin_N_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004846">
        <property type="entry name" value="T2SS/T3SS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00263">
        <property type="entry name" value="Secretin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07655">
        <property type="entry name" value="Secretin_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00811">
        <property type="entry name" value="BCTERIALGSPD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00965">
        <property type="entry name" value="STN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02519">
        <property type="entry name" value="pilus_MshL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="STN" evidence="6">
        <location>
            <begin position="99"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="171"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ42461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="565" mass="60477" checksum="1488AB3EB5C7E337" modified="2010-01-19" version="1">MRRVAVGLAIASLVGCSTNMGHRDPVEIKQALNQAVNDANNTSLTDLPEGVSADLMPNMDPMSGSSIVPSHVVEKRFQVNARNVEAKAFFTSLVKGTPFNMVIAPNVSGRITLKLKDVTLSEVLKVVSDMYGYEITRADNIIQVFPATLRTEIIPVDYLQLQRRGVSLTSITTGSVSDNDSSNGSSNSNNNNDDNNDSDSNGNNLSSGDSTTTGGTTIETTSKSDFWGQLQKAVQAMIGGAGDGRSVVVSPQASLISVRAYPNELREVKKFLGMSEQRLKRQVILEAKILEVTLNDSYQQGINWGNITRSIGSGGVTIGQPSVVNPVTGLINTLPGGNDISELLGGQTNITITDGNFSAVMRFLSTQGDLNVLSSPRVTAANNQKAVIKVGGDEYFVTNVSSSNVSGDNSTAAPDINLTPFFSGISLDVTPQIDDQGGVLLHVHPAVVDVTDEVKSIELGDKFGTYQLPLAKSSIRESDSIIHAHSGDVVVIGGLMKTSTHDQVSKVPLLGDIPGLGNLFRNINKVQQKTELVILLKPTVVGEQTWKQQLERSQSLLNEWFPENK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1U0</accession>
    <name>D0Z1U0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cell shape-determining protein MreB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">mreB</name>
        <name evidence="3" type="ORF">VDA_003504</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Forms polymers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="2">Membrane-associated.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the FtsA/MreB family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303629.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003504"/>
    <dbReference type="EnsemblBacteria" id="EEZ42471">
        <property type="protein sequence ID" value="EEZ42471"/>
        <property type="gene ID" value="VDA_003504"/>
    </dbReference>
    <dbReference type="GeneID" id="57340024"/>
    <dbReference type="eggNOG" id="COG1077">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="410781at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000902">
        <property type="term" value="P:cell morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd10225">
        <property type="entry name" value="MreB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02207">
        <property type="entry name" value="MreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004753">
        <property type="entry name" value="MreB"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01652">
        <property type="entry name" value="SHAPEPROTEIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00904">
        <property type="entry name" value="mreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0133">Cell shape</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="19"/>
            <end position="21"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="168"/>
            <end position="170"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="216"/>
            <end position="219"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="296"/>
            <end position="299"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ42471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="347" mass="36956" checksum="C1EB825B2297F753" modified="2010-01-19" version="1">MFKKLRGMFSNDLSIDLGTANTLIYVKGQGIVLDEPSVVAIRQDRAGATKSVAAVGHDAKQMLGRTPGNIAAIRPMKDGVIADFYVTEKMLQHFIKQVHDNSILRPSPRVLVAVPCGSTQVERRAIRESAQGAGAREVYLIDEPMAAAIGAGMPVSEATGSMVIDIGGGTTEVAVISLNGVVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERIKHEIGSAYPGDEVREIEVRGRNLAEGVPRSFTLNSNEILEALQEPLTGIVSAVMVALEQCPPELASDISERGMVLTGGGALLRDLDRLLTEETGIPVVVAEDPLTCVARGGGKALEMIDMHGGDLFSEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1V9</accession>
    <name>D0Z1V9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized ABC transporter ATP-binding protein YrbF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_003523</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303689.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003523"/>
    <dbReference type="EnsemblBacteria" id="EEZ42490">
        <property type="protein sequence ID" value="EEZ42490"/>
        <property type="gene ID" value="VDA_003523"/>
    </dbReference>
    <dbReference type="GeneID" id="57340002"/>
    <dbReference type="eggNOG" id="COG1127">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1058434at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030296">
        <property type="entry name" value="MlaF/Mkl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43023:SF6">
        <property type="entry name" value="PTHR43023:SF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="8"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="40"/>
            <end position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ42490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="270" mass="29324" checksum="A3B41AB13459BFFC" modified="2010-01-19" version="1">MDKQEALISVKNMTFSRGERKIFDNVSLTVPKGKVTAIMGPSGIGKTTLLRLIGGQIAPDEGEVWFDGHNIPTLGRSALYQVRQRMSMLFQSGALFTDMDVFDNVAFPLREHTQLPEELIRTLVLLKLEAVGLRGAAHLQPNELSGGMARRAALARSIALDPELIMYDEPFVGQDPITMGVLVELIGSLNQALGITSVIVSHDVPEVMSIADHVYLLSGGKVIGSGSPQELQANSDPRVRQFLDGDADGPVRFQFPAQDLQQELFGSSNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z225</accession>
    <name>D0Z225_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA 5-carboxymethoxyuridine methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">cmo5U methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">cmoM</name>
        <name evidence="3" type="ORF">VDA_001874</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>5-carboxymethoxyuridine(34) in tRNA + S-adenosyl-L-methionine = 5-methoxycarbonylmethoxyuridine(34) in tRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:54080"/>
            <dbReference type="Rhea" id="RHEA-COMP:13383"/>
            <dbReference type="Rhea" id="RHEA-COMP:13781"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:136879"/>
            <dbReference type="ChEBI" id="CHEBI:138053"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="1"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298854.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001874"/>
    <dbReference type="EnsemblBacteria" id="EEZ40842">
        <property type="protein sequence ID" value="EEZ40842"/>
        <property type="gene ID" value="VDA_001874"/>
    </dbReference>
    <dbReference type="GeneID" id="57342002"/>
    <dbReference type="eggNOG" id="COG2227">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1431378at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097697">
        <property type="term" value="F:tRNA 5-carboxymethoxyuridine methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02057">
        <property type="entry name" value="tRNA_methyltr_CmoM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033664">
        <property type="entry name" value="Cmo5U_methylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13847">
        <property type="entry name" value="Methyltransf_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Methyltranfer_dom" evidence="2">
        <location>
            <begin position="47"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="1">
        <location>
            <begin position="54"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="265" mass="30279" checksum="296FB08393F667E7" modified="2010-01-19" version="1">MIKDRNFDDLAQKFAKNIYGTAKGEIRQTVVWQDIEQILAELKSETPLQVLDAGGGLGQLSQRIAELGHHVTLCDLSSEMLNLAEQEIAKNGLLEQYRLVHCPVQEVGQFIEQPVDLILFHAVMEWLVDPISALSGLLEQIKPGGVISVMFYNYHGLLFKNLICGNLTHIEEGMPHRKRFKLQPQKGIRPEEVYQCLEDAGLEIMGKTGVRTFHDYMQKHRLGDYTFEQVLDMEQKLCRQEPYLSLGRYIHVYARKPSDNDLVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z247</accession>
    <name>D0Z247_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Phosphate transport ATP-binding protein PstB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001783</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001783"/>
    <dbReference type="EnsemblBacteria" id="EEZ40751">
        <property type="protein sequence ID" value="EEZ40751"/>
        <property type="gene ID" value="VDA_001783"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1117">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015415">
        <property type="term" value="F:ATPase-coupled phosphate ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:inorganic phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03260">
        <property type="entry name" value="ABC_PstB_phosphate_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005670">
        <property type="entry name" value="Phosp_transpt1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43423">
        <property type="entry name" value="PTHR43423"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="1"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="183" mass="20789" checksum="6DB83E8F08AF7229" modified="2010-01-19" version="1">MEDQDIYGNIDVAQLRIKVGMVFQKPNPFPMSIYENVAYGLRAQGIKDKKVLDEIVEQSLRGAALWDEVKDRLKSHAFGLSGGQQQRLCIARTIAMKPEVILMDEPTSALDPIATKKIEDLMESLKKEFTIVIVTHSMQQARRISDRTAFFLMGELVEHDETQVIFNQPQDDRTRGYVNGDFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2C0</accession>
    <name>D0Z2C0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein-methionine-sulfoxide reductase catalytic subunit MsrP</fullName>
            <ecNumber evidence="5">1.8.5.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">msrP</name>
        <name evidence="7" type="ORF">VDA_000571</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a quinone + H2O + L-methionyl-[protein] = a quinol + L-methionyl-(R)-S-oxide-[protein]</text>
            <dbReference type="Rhea" id="RHEA:51296"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12314"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:45764"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a quinone + H2O + L-methionyl-[protein] = a quinol + L-methionyl-(S)-S-oxide-[protein]</text>
            <dbReference type="Rhea" id="RHEA:51292"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12315"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:44120"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </cofactor>
        <text evidence="5">Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the MsrP family.</text>
    </comment>
    <dbReference type="EC" id="1.8.5.-" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000571"/>
    <dbReference type="EnsemblBacteria" id="EEZ39551">
        <property type="protein sequence ID" value="EEZ39551"/>
        <property type="gene ID" value="VDA_000571"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2041">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043546">
        <property type="term" value="F:molybdopterin cofactor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016672">
        <property type="term" value="F:oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030091">
        <property type="term" value="P:protein repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01206">
        <property type="entry name" value="MsrP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022867">
        <property type="entry name" value="MsrP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000572">
        <property type="entry name" value="OxRdtase_Mopterin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036374">
        <property type="entry name" value="OxRdtase_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00174">
        <property type="entry name" value="Oxidored_molyb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56524">
        <property type="entry name" value="SSF56524"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 5" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="4 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Oxidored_molyb" evidence="6">
        <location>
            <begin position="111"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Molybdopterin binding" evidence="5">
        <location>
            <begin position="94"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Molybdopterin binding" evidence="5">
        <location>
            <begin position="252"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </ligand>
        <ligandPart>
            <name>Mo</name>
            <dbReference type="ChEBI" id="CHEBI:28685"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="241"/>
        </location>
        <ligand>
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="337" mass="38265" checksum="3FB5980AA86FF643" modified="2010-01-19" version="1">MIKKSQSWMISENEVTPETIFKQRRDILLKLGITATALPFAAQSKAGLLDLFSSDEPSKTVDHRQNLAGVSSPLSTSDLSLTPESKILEYNNFYEFGATKSDPARLAANFKTDPWTVEIDGLVKNPIKLHHEDLLKKFTIEERIYRMRCVEAWSMNIPWLGFQLSDLLKLVEPTSEAKYVAFQTLYDPKEMPGQASRSLGGGIDYPYVEGLRLDEAMNPLTLMSVGLYGKTLAPQNGAPIRLVVPWKYGFKSIKSIVRITLTDKEPPTTWNRLAPQEYGFYANVNPNVDHPRWSQASERFIGQGSVFSSRRQKTLMFNGYEDQVAYLYKGMDLRKNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2E0</accession>
    <name>D0Z2E0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000591</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39571">
        <property type="protein sequence ID" value="EEZ39571"/>
        <property type="gene ID" value="VDA_000591"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3528">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018707">
        <property type="entry name" value="LpxR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037107">
        <property type="entry name" value="Put_OMP_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09982">
        <property type="entry name" value="DUF2219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="343" mass="38601" checksum="2A4CA900EF34614C" modified="2010-01-19" version="1">MPVDKTIARTIMLALPVTIILPTSGHTSTDFNSSTWSVSIDNDGILGTDKNYSNGLFLEYHSERVNNLALSSPWPYRIAGQLFSSDVEQTLSWNWRIGQQMWTPSDIESQQPVINERPYAGLLFVDLGINRYQPNLTQKYQLRLGTVGPRALAKHTQKTIHDWIGSDNPNGWNNQIKNQWIANFSYQQHNTLYSSPISDFLHSQWDVASLARASIGNDQSDLAAGITLRWGQDLTKSLGAIGFTPGEFVDVSALSASRSGYFLFTGIEGRYKFNDITIEGKRPDETYPAHLEPWQASVVLGGVFYRPTWGITLSLATHTKEFKQSMDTTHSNGSVEFFWRFPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-12-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2I0</accession>
    <name>D0Z2I0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Integrase/recombinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000631</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304920.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000631"/>
    <dbReference type="EnsemblBacteria" id="EEZ39611">
        <property type="protein sequence ID" value="EEZ39611"/>
        <property type="gene ID" value="VDA_000631"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4974">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="745068at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0229">DNA integration</keyword>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyr recombinase" evidence="3">
        <location>
            <begin position="276"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="468" mass="53978" checksum="36E3F97E166454C3" modified="2010-01-19" version="1">MQNLILRNNDLLAPNRSLIETKHNYASSISINPALAYIYSLAATDTSGGRINAKYTLERFARFNLGPSFVKVDWQFLVKQPRLIQKLLHSFFIYRAKQKAEAKQLRHYSLKNLQVTPLINALLELSNFMFFNGDISEYELKKWQNQLSNYVIEDIETPIEPSSSAENRIDYSLSLSVRSQISLEAFSCFYIGSCIERMDWYQVLYAPVLQNLMQQFLSERNDRNLIKTGSYSPATADNLLRMLRGVAHHAWLSESITVETLERIKAIKLPRGSRQSSGRYLSYSELDKISAICLNQTNKIKGIRDNAIFWLMYESGLRRAEVVNLSLDDIDINRGTIHVVGKGNKERYVPFSLESDLYRALSKWFDVRYKLQGNIFNSLFCVVNKHQQVVEKSLTTQSLNDLCKQIQRMGFERMVSPHDFRHSVATNLLRAGHDLLLVSKFMGHSSVTTTQRYDRRSDDDLKGLALRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2L1</accession>
    <name>D0Z2L1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">H-REV 107-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000662</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304986.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39642">
        <property type="protein sequence ID" value="EEZ39642"/>
        <property type="gene ID" value="VDA_000662"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5033VNZ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1840661at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007053">
        <property type="entry name" value="LRAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04970">
        <property type="entry name" value="LRAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="LRAT" evidence="2">
        <location>
            <begin position="7"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="165" mass="18157" checksum="57132B98CFBB2F68" modified="2010-01-19" version="1">MTISGYQVQPGDIVAVDFGRYDHWALVSDKVCHQGKRMLISATKRNGTVMEETWDEVTQGQKVVLSKLHCHNDVRGSLEKARSQIGVWRYSIYKRNCEHFIYWVLSDKLRSKQVIGGVSGAVLGAIGVVTLSKKPSVLKVLGGAWAGLSSGVILAKASNKTRKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2W5</accession>
    <name>D0Z2W5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cyclic-guanylate-specific phosphodiesterase</fullName>
            <ecNumber evidence="3">3.1.4.52</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">VDA_000766</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>cyclic di-3',5'-guanylate + H2O = 5'-phosphoguanylyl(3'-&gt;5')guanosine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24902"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58754"/>
            <dbReference type="ChEBI" id="CHEBI:58805"/>
            <dbReference type="EC" id="3.1.4.52"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="3.1.4.52" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305284.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000766"/>
    <dbReference type="EnsemblBacteria" id="EEZ39746">
        <property type="protein sequence ID" value="EEZ39746"/>
        <property type="gene ID" value="VDA_000766"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2200">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071111">
        <property type="term" value="F:cyclic-guanylate-specific phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024744">
        <property type="entry name" value="CSS-motif_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12792">
        <property type="entry name" value="CSS-motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0973">c-di-GMP</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0418">Kinase</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="14"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="216"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="11">
        <location>
            <begin position="247"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
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        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ39746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="479" mass="54944" checksum="6C788453C2A75680" modified="2010-01-19" version="1">MLQKLPKIFTKKKYVFILFVFMSWFVLSACFLLMDYAYKRHKLMNYAQETVQVFNSIFNHANSSINLAEKVDYLDCDKSLNQLRQIAAVTPYVRSIVILHNNKLICNSVLGKTNFPVNRNLKHQKLAIIDKSYITKKPVLILTKKINENSEIRIGINTYFLSHNLISSTEDRELYIEIDDAIYNLDGVARSIDTSDGYIRVSSLLYPFSIYVDDSFVLTSLDMTFVLFMLLTGIVVGGYGNRIFSKTDFVKYELENAILNNEIKPYIQPISSSNGDVIGGEVLARWVKSNDRVIPPSVFIPLIEQYDLMESMTNAMIDQLINTPNLLESNKSLHLSINVTKECLENEIIRIKCEWLAEQCRLILELTESEEFTDPEYISLLMSELRERGVLFALDDYGTGFSTLKYLKQYQFDYLKIDKMFIDNVCDDSVSSEIIKNIISLAKKLNISLVAEGVEHQCQVHKLSNYGVDISKAIILVNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2W6</accession>
    <name>D0Z2W6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000767</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39747">
        <property type="protein sequence ID" value="EEZ39747"/>
        <property type="gene ID" value="VDA_000767"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031NJY">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="74" mass="8435" checksum="85FAF407A2DA9ED3" modified="2010-01-19" version="1">MLELEGKDLTQLTKQEKEVFDAFEARAHEFGVTIEIASEAPLSDIKQGTSSYSVTQLERHFPNQIIIKRVLDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z306</accession>
    <name>D0Z306_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000807</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305405.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000807"/>
    <dbReference type="EnsemblBacteria" id="EEZ39787">
        <property type="protein sequence ID" value="EEZ39787"/>
        <property type="gene ID" value="VDA_000807"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003020032" evidence="1">
        <location>
            <begin position="23"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="117" mass="12572" checksum="FA583373396B82BB" modified="2010-01-19" version="1">MKKQISVLALSLAAVFSAAVFAGNGVDTTMDKAAMDAKQDAHAVMKDASSDSKDAMIDIKDELNKGTEDVMKMAEKEGNAESHAINKHSDAMKIDKDAMKEEAATQVQEKVIKEVTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z307</accession>
    <name>D0Z307_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000808</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305408.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000808"/>
    <dbReference type="EnsemblBacteria" id="EEZ39788">
        <property type="protein sequence ID" value="EEZ39788"/>
        <property type="gene ID" value="VDA_000808"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1552415at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="182"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="227"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="269"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="295"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="356"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="383" mass="43012" checksum="73805D924B573677" modified="2010-01-19" version="1">MSWKSLLRFELKAIFTNPALLFTVFGGIVIYSFLYPLPYSEQLPREQRVAVVNLDQSQLSRKLIRMADATPQVEITEHLGSIYSAQQQLEQSNIDGILVIPENFYRDVLLGKSPTLAYAGNAALFLVYGTVVEGLASAGGTLGAHIKVSHMVMDGHNIALAAKQYSAMKLNMRPIFNTTMGYINYVVPAVFVLILHQTLLIGVSIIGGEHNERRAEGEIGYWMTYPAWKIIFVRTILFVLIYIPLTMYYFGWSFDYYDISKLAKVPELLLLTVPFLVSVISLGLVIGQLIPRRELATLIVLLSSLPLVFSAGFIWPTAELPTIIKGFAQLVPSTPAINGFLRLNQMGASFTQVAPYFWQMWLQAVIYFMLAWGLMSRNRSHLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3C6</accession>
    <name>D0Z3C6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000927</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305742.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39907">
        <property type="protein sequence ID" value="EEZ39907"/>
        <property type="gene ID" value="VDA_000927"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0697">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1179190at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="184"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="219"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="251"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="277"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="13"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="159"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="312" mass="34725" checksum="0A4E571838329241" modified="2010-01-19" version="1">MERNDSLTRIFYIVLMGFGFPIMRYMSIHFDTLNNNAIRFLSGGIFFCVICLFKFREEIKTILKDYRTVLSLFLLATFMTANMFFFINGLKYTSAISGSIFGILAMPLGIIFASIFYPDERKIVTNRRFAYGAIIAFLGSLVFVLNSHYSNGNEIIYTGYIYLTCAITIQSIQNLIVKKLALNLPAIVISASTATLSGIIFLAIAIYTDTFSNLKEVPFTLITGLIFAGIYGMLTGMLMAFYILKKQGVAIFNMTQLLIPISTGIIGYMTLGETISTMQMIGGIIVICGCILASRREHTKKVVSDTLSTSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3I7</accession>
    <name>D0Z3I7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000988</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39968">
        <property type="protein sequence ID" value="EEZ39968"/>
        <property type="gene ID" value="VDA_000988"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="52" mass="6206" checksum="AEAEF66D512CF6E0" modified="2010-01-19" version="1">MNPILTDRVNPRSYQITQSKVKVDQFLNSQGDMIYQPIVDITYRYEARDRNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3L2</accession>
    <name>D0Z3L2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Diguanylate cyclase DosC</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Direct oxygen-sensing cyclase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_001013</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305987.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001013"/>
    <dbReference type="EnsemblBacteria" id="EEZ39993">
        <property type="protein sequence ID" value="EEZ39993"/>
        <property type="gene ID" value="VDA_001013"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3706">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019825">
        <property type="term" value="F:oxygen binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009050">
        <property type="entry name" value="Globin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044398">
        <property type="entry name" value="Globin-sensor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012292">
        <property type="entry name" value="Globin/Proto"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11563">
        <property type="entry name" value="Protoglobin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46458">
        <property type="entry name" value="SSF46458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GGDEF" evidence="7">
        <location>
            <begin position="235"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00015125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ39993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="378" mass="43957" checksum="2B3FC68A46CDB7B5" modified="2010-01-19" version="1">MDARNLIYQTLAEQLNINEHDIEQRKISLSFVEQDEVNLQQCLKWLEPLIPQVVQEFYQHQVSIPEIALIIGDKDTLKRLHYSMSQYITELFSGSYDMDYVAKRLQIGRIHQRIGVTPKLYLSGINRLQHLLEDIIRDYSEDELQTNQILSSLKKLMYFDNQLVFDTYISTLQSEVIVANKQLESYANNLEQIVSDRTQRLEELALKDALTSLYNRHSFQEIVDKNISYAERTSGWGSLLYLDINRFKEVNDTFGHQAGDQVLIELADSMRETLRKSDSAARHGGDEFCIWLPNTALKKTQILVERLCRHFDQHKSHDVSLSIGVTSVYPEHYLPFEKLLIEADELMYQAKKIAHQTHQNEVMYHQDLSTVTMLQSAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-06-02" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3X6</accession>
    <name>D0Z3X6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Serine transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001129</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306292.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001129"/>
    <dbReference type="EnsemblBacteria" id="EEZ40107">
        <property type="protein sequence ID" value="EEZ40107"/>
        <property type="gene ID" value="VDA_001129"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="154"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="184"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="223"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="266"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="320"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="363"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="386"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="421"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="442" mass="48587" checksum="71E2604C1F6C5227" modified="2010-01-19" version="1">MSDITPAVKSACNTKVSPHIRANMSEQEWKQAIKFDSVDIGWIVMSIGMAIGAGIVFLPVQVGVMGLWVFLLSSIIGYPAMYLFQKLFINTLAESKECTDYPGVISGYLGKNWGVALGILYFLMLVIWVLVYSLAVTNDSSSYLHTFGITEGHLNQNAFYGLALICILAFIGSKGEKLLFKLSGFMAVTVLTLVGVMGVLLISRWDFNNIPAMGNMGTMIKDAIITLPFTLTSILFIQSLSPMVISYRSHEKSIEVARYKASRAMTIAFSILFVVVFFFAISFTFAINQEQAHEAMQQNISALAIIAHYFPGSWATITGIVINIFAVVTSFFGVFLAFQEACRGLAMNLLLRKFEESQINRQLVNKLVTVFIILLAWSAVALNAPILSFTSICSPIFGLVGCLIPAYLVYKVPSLHKYKGVATNLIIITGILLCISPLLAFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-08-12" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z426</accession>
    <name>D0Z426_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Sulfur carrier protein FdhD</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">fdhD</name>
        <name evidence="4" type="ORF">VDA_000282</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FdhD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303936.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000282"/>
    <dbReference type="EnsemblBacteria" id="EEZ39264">
        <property type="protein sequence ID" value="EEZ39264"/>
        <property type="gene ID" value="VDA_000282"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1526">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="948173at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097163">
        <property type="term" value="F:sulfur carrier activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016783">
        <property type="term" value="F:sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00187">
        <property type="entry name" value="FdhD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003786">
        <property type="entry name" value="FdhD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30592">
        <property type="entry name" value="PTHR30592"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02634">
        <property type="entry name" value="FdhD-NarQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015626">
        <property type="entry name" value="FdhD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00129">
        <property type="entry name" value="fdhD_narQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Cysteine persulfide intermediate" evidence="3">
        <location>
            <position position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="276" mass="30392" checksum="CEABA9ECF325C8C0" modified="2010-01-19" version="1">MNTCEVLPDIDFANSCERSIVRYRKGQDEHREWDFIIEEMPVAVAFNGVAYTVMMCTPNDLEYFAIGFALSEGIIDHHRDIHDIEITKLENGIDLNVIVANRCLLRLKQKRRSLAGLTGCGICGEEKLDTVCRALLPVTSHAEFDLCHLEPALAQLLAKQQLNQLTGSAHAAVYLTPEGCIEAIFEDVGRHIALDKLVGFISQRQLSGGAVLVTSRASFEMVQKVASAGVEILFAISSATKMAVDLAERLNVTLVGHCRHGRADAYSHSERIVGML</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z479</accession>
    <name>D0Z479_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Nucleotidyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000335</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000335"/>
    <dbReference type="EnsemblBacteria" id="EEZ39317">
        <property type="protein sequence ID" value="EEZ39317"/>
        <property type="gene ID" value="VDA_000335"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0433">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008571">
        <property type="entry name" value="HerA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42957">
        <property type="entry name" value="PTHR42957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="407" mass="46579" checksum="0083157D60F07827" modified="2010-01-19" version="1">MLLDFNGEYIKDQIVSLEHKHAIDLNTNTAVDQFPLAEDEFWNVETLSILFQATTNTQKPFINRVLQGRSKYGSGKASALSYLKYTIKFCFTSSSQKPEVLDLIKSVLKSTNQAKILDKVCWHGNKYKLLRDNMSDVFFNGESEYDIYLKNIVDSIQINDLDAFQEFKILCKLKLINDLMFNYVQFDHIQPLLKRAESSLGGLSKVIKVESSVAVDDKAITVISLRNCNQDVKKIIPLLVTKHYYNSHKKQVKKSPPEKTLHLIIDEAHNILSQQSVREQANWKDYRLELFEELIKEGRKFGIFLTLSSQRPADISATIMSQLHNFFIHRLVNDRDLFLLDNTISTLDSVSRSLIPNLSRGSCIITGTSFDLPMLIQVDELNDNCKPDSNDVLLESLWSVKTEEESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z485</accession>
    <name>D0Z485_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Putrescine-binding periplasmic protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000341</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for the activity of the bacterial periplasmic transport system of putrescine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial solute-binding protein PotD/PotF family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304094.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000341"/>
    <dbReference type="EnsemblBacteria" id="EEZ39323">
        <property type="protein sequence ID" value="EEZ39323"/>
        <property type="gene ID" value="VDA_000341"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0687">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1264541at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019808">
        <property type="term" value="F:polyamine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015846">
        <property type="term" value="P:polyamine transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001188">
        <property type="entry name" value="Sperm_putr-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019574">
        <property type="entry name" value="Periplasmic_polyamine_BP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00909">
        <property type="entry name" value="SPERMDNBNDNG"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0574">Periplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003020072" description="Putrescine-binding periplasmic protein" evidence="3">
        <location>
            <begin position="23"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>spermidine</name>
            <dbReference type="ChEBI" id="CHEBI:57834"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>spermidine</name>
            <dbReference type="ChEBI" id="CHEBI:57834"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR019574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR019574-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="343" mass="38999" checksum="988F1DE4928091AE" modified="2010-01-19" version="1">MKKILKGVTTLTFALSAFNVSAANDVLNVYNWAEYMPDSVLKAFEKEYDVTINYSTFDNNEAMYTKLKLLDNKGYDVVFASTYFIEKMAREGMLAKIDHSKIPNLANVYPGLLNQEFDPKNDYSAPYVWGVTGISYNSELVTTPITGWKDLWNADFARQVMLLDDVRDVFGMALKAQGHSINTTNEAEIKQAYESLQKLRPNVVVYNSDAPHVPYVTGEASIGMQWNGNAYMAKQEMKELEFVYPKEGSILWMDNFIIPAGSANKELAEKFINFIYRPENQAKIVEEFGFPPATKDAKSHLPKEIQDNPIIFPSEEDINKGEFTNDVGKAVNIYQKYWQLLKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z487</accession>
    <name>D0Z487_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">5'-nucleotidase</fullName>
            <ecNumber evidence="5">3.1.3.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_000343</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the 5'-nucleotidase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.5" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000343"/>
    <dbReference type="EnsemblBacteria" id="EEZ39325">
        <property type="protein sequence ID" value="EEZ39325"/>
        <property type="gene ID" value="VDA_000343"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0737">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106411">
        <property type="term" value="F:XMP 5'-nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009166">
        <property type="term" value="P:nucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008334">
        <property type="entry name" value="5'-Nucleotdase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036907">
        <property type="entry name" value="5'-Nucleotdase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006179">
        <property type="entry name" value="5_nucleotidase/apyrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575">
        <property type="entry name" value="PTHR11575"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02872">
        <property type="entry name" value="5_nucleotid_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01607">
        <property type="entry name" value="APYRASEFAMLY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55816">
        <property type="entry name" value="SSF55816"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="3">
        <location>
            <begin position="14"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="5_nucleotid_C" evidence="4">
        <location>
            <begin position="291"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="555" mass="60512" checksum="4A77439B34C9E8D6" modified="2010-01-19" version="1">MNAALLSQMGLDGMALGNHEFDLSNKKLNQFIDSVNFPILAANVDVSQDPDLKDQKNLHPFRVFAFDGNKKTVVTDLNHLPKDKNLVAVFGLALDDMPNIAPHTGKVKFNNMVKSAQATVDYLQSKGVDNIIALTHIGNSVDLNLASKVNGIDLIVGGHSHTLLGDFTNLGLSNNGTYAQMVKNPNGVGETCVVQAGEYAQAIGRVNVTFDAQGDVVSCKGHNTLLSNDEFFHSADRLANEKFSAKDTAKVEQFIDEQENIVIAPEDSAMRSEIDTQYKPAVDKAYGKTIGQVPVELKHERRPGDRGTDDHGSDVAPIVAEGQYYWTNTPAVRKVTGMKVDFSLIGAGGIRTNIEAGEYREGNVSLELLPFSNFMSVVPVKGRAIRELLQNAVSATLPEGSHAGKFPYGGHIRYTFTETSAHKAGKLNSVEVMTGTEKHPVWTPLDDNKTYNVAINNYNATGNDGWTPLYTSQKDHSGRVDLVYVNGKLTGYKVKNIAKNGDKYKVNYVGGKAPNCKAENVRCNTDAQSVIDYIANDRQTVTPLSYEVVTFNRAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4D4</accession>
    <name>D0Z4D4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glutathione-regulated potassium-efflux system ancillary protein KefG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000390</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304232.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000390"/>
    <dbReference type="EnsemblBacteria" id="EEZ39372">
        <property type="protein sequence ID" value="EEZ39372"/>
        <property type="gene ID" value="VDA_000390"/>
    </dbReference>
    <dbReference type="GeneID" id="57343228"/>
    <dbReference type="eggNOG" id="COG2249">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1143659at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003680">
        <property type="entry name" value="Flavodoxin_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02525">
        <property type="entry name" value="Flavodoxin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin_2" evidence="1">
        <location>
            <begin position="5"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="204" mass="23502" checksum="7AA4DC9DA98FB633" modified="2010-01-19" version="1">MAEKKKILLLFAHPSPERSEVNFPLFRASQTVDNVTTVDLYAEYPTFRINIDREQQRLCEHDIIIFMFPLYWYSTPAILKEWQDLVLEYGFAYGSEGTKLHGKTFLCALTAGGAESAYRHEGYNHYTIRELLQPLEQMADLTGMDFIAPFALFGARTAVEEHRVGSHINNWKQVLIALRDNKFDLALAKTLSKLNHHLPELIKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4E5</accession>
    <name>D0Z4E5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000401</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304266.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000401"/>
    <dbReference type="EnsemblBacteria" id="EEZ39383">
        <property type="protein sequence ID" value="EEZ39383"/>
        <property type="gene ID" value="VDA_000401"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3157">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1153621at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036624">
        <property type="entry name" value="Hcp1-lik_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008514">
        <property type="entry name" value="T6SS_Hcp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05638">
        <property type="entry name" value="T6SS_HCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141452">
        <property type="entry name" value="SSF141452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03344">
        <property type="entry name" value="VI_effect_Hcp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="172" mass="19111" checksum="729EECF51009333B" modified="2010-01-19" version="1">MPTPCYISIQGKTQGNITAGAFTADSVGNIYVEGHEDQMLVQEFKHIVTVPTDPQSGQPAGQRVHKPFKFTVALNKAVPLMFNSLASGEMLPKVELKWYRTSVEGKQEHYFTTTLTDATIVDINTHMPHCQDPSKADFTQLIEVSMAYRKINWDHTISGTSGADDWRAPLEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4F4</accession>
    <name>D0Z4F4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Aspartate racemase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000410</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304290.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000410"/>
    <dbReference type="EnsemblBacteria" id="EEZ39392">
        <property type="protein sequence ID" value="EEZ39392"/>
        <property type="gene ID" value="VDA_000410"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1794">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1359310at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036361">
        <property type="term" value="F:racemase activity, acting on amino acids and derivatives"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015942">
        <property type="entry name" value="Asp/Glu/hydantoin_racemase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001920">
        <property type="entry name" value="Asp/Glu_race"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01177">
        <property type="entry name" value="Asp_Glu_race"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53681">
        <property type="entry name" value="SSF53681"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="353" mass="38363" checksum="5651CEDE41304D7F" modified="2010-01-19" version="1">MGSTRIGVIGGMGNEAMVDLIEKINGSISASDSIELVAFGNSRLAYKAEEVGQQWQATDTPELRKYATATYTLRLMQYLDVKVMGLACNSAHELFRTILPQIPVHFVDMIKQTAASLEGSEDTILVMGVNSLVDSGLYQSALADQGVKSTKPSLENQQKVMDAIYHPEFGIKTAKITPQAEQLLCEVICDELAKQGCTKIVLGCTELPLALTAESCLRFKQQGLLPPEITVIDASMVLAQSLISTLGDASSLIEPLQSYQQPYLDWIAPLAVSVSSLEQLASIQKQIFAQTTSYLAKNNKSLTGSYMHLPTLFFTDNAKGVADKLRSIDIEVIDGDDLTAADIEQALQRHLAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4L1</accession>
    <name>D0Z4L1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MSHA pilin protein MshA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000469</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304449.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000469"/>
    <dbReference type="EnsemblBacteria" id="EEZ39449">
        <property type="protein sequence ID" value="EEZ39449"/>
        <property type="gene ID" value="VDA_000469"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2165">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1986406at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="187" mass="20247" checksum="0BE43AEBE2C5DFC0" modified="2010-01-19" version="1">MKRNGFTLIELVVVIVILGILAVVAAPKFLNLQQDARDASLKGLKGSIESTLDVTYAKLATLGLENAAYVVDKPTGKHENEVVADLSTFGCNKDGRCLFEYGYPSDYGPTLAVLVNGISANEHAPSDDFVAVRKGKTSDDLAITFKNNVERLSSNQVVLKPDASCYIDYSRPSKDKPRPVLTIVPCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-08-12" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4L7</accession>
    <name>D0Z4L7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Probable potassium transport system protein kup</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">kup</name>
        <name evidence="12" type="ORF">VDA_000475</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Transport of potassium into the cell.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cell membrane</location>
            <topology evidence="11">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the HAK/KUP transporter (TC 2.A.72) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304466.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000475"/>
    <dbReference type="EnsemblBacteria" id="EEZ39455">
        <property type="protein sequence ID" value="EEZ39455"/>
        <property type="gene ID" value="VDA_000475"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3158">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="589903at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015079">
        <property type="term" value="F:potassium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01522">
        <property type="entry name" value="Kup"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003855">
        <property type="entry name" value="K+_transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023051">
        <property type="entry name" value="K+_uptake_low_affin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30540">
        <property type="entry name" value="PTHR30540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02705">
        <property type="entry name" value="K_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 11" id="KW-0630">Potassium</keyword>
    <keyword evidence="5 11" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="45"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="138"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="168"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="208"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="244"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="286"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="336"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="363"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="396"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="422"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ39455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="620" mass="68884" checksum="8ACAEFC8A3BCE0A9" modified="2010-01-19" version="1">MQNQKQSLLVLTCLSIGIVYGDIGTSPLYAFKAMFDGEHSIAINQANVFGILSLVFWTFILTVCIKYLSLVTQASNKGEGGILTLASLAHGVAPKQLKISILFLGMLAAGFFFGEAIITPAMSVLSAVEGISVINPDLQPMILPISITIICALFAIQKFGSGKIGQLFAPVMLIWFVCIGVLGANAIIDNPIVIKALSPHYAVGFIFHHGVATLFTLGVVVLAVTGVEALYADMGHFGIKPIRLAWFFVVMPCLVLNYFGQGALVLSHAKAIENPFFMLAPNALRLPLVILATFATVIASQAVISGIFSLTRQAINLGFLPPVRIHHTSHHEQGQIYVPMANFLLFILVITVVVTFGSSTRLAAAYGIAVTATMLISSLFILVVSRYLWNWSRKTVITYAILMVSYDLLLFISTSLKFADGGWLPLTIGSLVFLLMIIWYQERERITTLFKPSLSIDAMVKELEQKQWSRASGTAVYLSSNENQVPSSLVNNLKYNEILHERNVLLTYKYVDQPWVHPLKRLEVRQLSPSFWQMIAYVGYQETLDIEQIYHGCCTKELTLHPAETIFFMSSERMKVKHVSWWHDLKARLFILLSRNALRTSERLSVPQDRLIEIGVHLEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4Q2</accession>
    <name>D0Z4Q2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Ribokinase</fullName>
            <shortName evidence="10">RK</shortName>
            <ecNumber evidence="3 10">2.7.1.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">rbsK</name>
        <name evidence="13" type="ORF">VDA_000510</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>ATP + D-ribose = ADP + D-ribose 5-phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13697"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:47013"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.15"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="10">Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.</text>
    </comment>
    <comment type="activity regulation">
        <text evidence="10">Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.</text>
    </comment>
    <comment type="pathway">
        <text evidence="10">Carbohydrate metabolism; D-ribose degradation; D-ribose 5-phosphate from beta-D-ribopyranose: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the carbohydrate kinase pfkB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.15" evidence="3 10"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000510"/>
    <dbReference type="EnsemblBacteria" id="EEZ39490">
        <property type="protein sequence ID" value="EEZ39490"/>
        <property type="gene ID" value="VDA_000510"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0524">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00916">
        <property type="reaction ID" value="UER00889"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004747">
        <property type="term" value="F:ribokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019303">
        <property type="term" value="P:D-ribose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01174">
        <property type="entry name" value="ribokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01987">
        <property type="entry name" value="Ribokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011877">
        <property type="entry name" value="D_ribokin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002139">
        <property type="entry name" value="Ribo/fructo_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00990">
        <property type="entry name" value="RIBOKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02152">
        <property type="entry name" value="D_ribokin_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00584">
        <property type="entry name" value="PFKB_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 10 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 10" id="KW-0630">Potassium</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="12">
        <location>
            <begin position="2"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="5"/>
            <end position="9"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="218"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="186"/>
            <end position="191"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="214"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="217"/>
            <end position="218"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="218"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="242"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="248"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="251"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="253"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="257"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ39490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="272" mass="28528" checksum="514A0C3735A85099" modified="2010-01-19" version="1">MIPGGKGANQAVAAARLGADIAFIACVGDDSFGHSMREAFATEGMNVEAVMIEENMPTGIAMIQVVATGENSICISAEANGCLTAEKLAPHHHLIEQADTLLMQLETPLCAIEQAAKVAKAAGTKVVLNPAPAKVLSDELLACVDLITPNETEAEVLTGIKVVDMDSAQQAAEALHAKGIERVMITLGSKGVWISQNGHGEQVEGFRVKAIDTTAAGDTFNGALLTALQEEMPLRDAIRFAHAAAALSVTRFGAQTSIPTRNDVELFLTQQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4V0</accession>
    <name>D0Z4V0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Lipoprotein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">VDA_000183</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell outer membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the YscJ lipoprotein family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000183"/>
    <dbReference type="EnsemblBacteria" id="EEZ39167">
        <property type="protein sequence ID" value="EEZ39167"/>
        <property type="gene ID" value="VDA_000183"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4669">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006182">
        <property type="entry name" value="FliF_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003282">
        <property type="entry name" value="T3SS_HrcJ/YscJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043427">
        <property type="entry name" value="YscJ/FliF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30046">
        <property type="entry name" value="PTHR30046"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01514">
        <property type="entry name" value="YscJ_FliF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01338">
        <property type="entry name" value="TYPE3OMKPROT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02544">
        <property type="entry name" value="III_secr_YscJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="8 9 11" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 9" id="KW-0564">Palmitate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="236"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="YscJ_FliF" evidence="10">
        <location>
            <begin position="39"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ39167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="265" mass="29169" checksum="4F5973B9E2EF3C92" modified="2010-01-19" version="1">MMKAIVMTKAVVTMKSVITRKTMRAVSMLLVLFLVGCQAELYTGVSQKEGNEMLSVLLSEGVVATKEPDKDNTVKLMVDNAQIAFAIDALKRKGYPREQFSTLKEVFPKDDLISSPLAERARLIYAKSQELSATLSQIDGVLVARVHVVLKDQNLRPGERPTPASASVFIKHAADVALDSYVPQIKLLVNNSIEGLNYDRISVVMVPSSEVRVTPQGNQFESILSIQVTKDTASHLIVILVFLVLLIIGSNVATFAWCRRNVKRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4Y5</accession>
    <name>D0Z4Y5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Riorf46 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000218</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39202">
        <property type="protein sequence ID" value="EEZ39202"/>
        <property type="gene ID" value="VDA_000218"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2801">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="2">
        <location>
            <begin position="111"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="391"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="437" mass="51282" checksum="8BC6FF4E6495404C" modified="2010-01-19" version="1">MFAKNESNAKMLLNILNVSVRQVQRLVTRFRQHGAAAIVHQRRGQPSSNRINYSVKLRCLFLIREHYTDFGPTLAHEKLTERHDIHVSVETIRQWMLADGLWVPHTKRKPRVYQPRYRRDCYGELIQIDGSHHDWFEGRSNKCCLLVFIDDATGKLMNLRFSETESAFDYMVATREYLEQHGKPTAFYSDRHAVFHVSKRDAKTERLTQFGRVLHDLNIELICANSSQAKGRVERANKTLQDRLVKEMRLQGIDTIEQANAWLPDFIADFNRRFAKPAKYPKDMHRPVREMTDELNDIFAWQELRKLSKSLTFQYDKVVYLIDPTEENQRLINQVVKVLDRPDGTIAIQYGQRKLTFKVFDKLADIDQGQIVDNKRLGAVLKFAQEKQQEFEQQQTRSRSKKAPKRTAQQRAIRQLEAINPVLVHPEQFKPSTRKKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z525</accession>
    <name>D0Z525_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000258</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306757.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39242">
        <property type="protein sequence ID" value="EEZ39242"/>
        <property type="gene ID" value="VDA_000258"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="251" mass="28283" checksum="A3AA31A5604778C6" modified="2010-01-19" version="1">MNTRSKTATKFYTSERADSSVQIGLAGREVDLESVMSEGNATHHLSSLDVSQGTDVTDIKEDPSLILRTLKAGRLRKNAKTVEQVQSLVKASTGIFVHEVNWNRGVTETDFWDWFHRMWPNITIEVSCGQSGLTNEVRFFSLGQRKHCALARLVFHDLKKAAFKKAVKSEINRLLTAILDDEDFLQDDKMRAIGSRFDRMYDRANLSAFDTEERETQRLAAQAVALGILGLLNCGKSTVSPKVKKWAELLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z539</accession>
    <name>D0Z539_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">IncF plasmid conjugative transfer pilus assembly protein TraU</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000274</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306794.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000274"/>
    <dbReference type="EnsemblBacteria" id="EEZ39256">
        <property type="protein sequence ID" value="EEZ39256"/>
        <property type="gene ID" value="VDA_000274"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502Z7SA">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1609287at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009649">
        <property type="entry name" value="TraU"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06834">
        <property type="entry name" value="TraU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003020025" evidence="1">
        <location>
            <begin position="23"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="336" mass="37428" checksum="1CE15A8CBE7767DA" modified="2010-01-19" version="1">MKYKIPWLIGLSLLTQSFYASATGPACRGRFMNPITDVCWECLFPITLGSVPLVPSRHPDTHNPSLPISFCPKPPPLFMQIGLNIGYWEPYAITDVTRVPFCMVNMGISTGGATSALIGGQSTNKGQGKGSNGGFYHAHWYKYPLIYWLQLLQSAACMATDNFDVSYLTEIDPFWDDDELSFILNPEAILFGNPIAQLACVAEAVKTSTSFFLPIDALFWCLGSQGSAYPLTGTTDYRDTPMQSAVLMAERLNYKLHRQGIVWESLGVDGAVCVQHPMPILPKSRYRYQLSNVIPDPFNCYPYGTTTAIWESGHDNPVTGDNFGFVQWRKRNCVFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z548</accession>
    <name>D0Z548_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type II/IV secretion system ATPase TadZ/CpaE associated with Flp pilus assembly</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000098</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306841.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000098"/>
    <dbReference type="EnsemblBacteria" id="EEZ39082">
        <property type="protein sequence ID" value="EEZ39082"/>
        <property type="gene ID" value="VDA_000098"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0455">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1046589at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="409" mass="46079" checksum="F4C73B89B977F934" modified="2010-01-19" version="1">MFDLVDVLKNKNLDSVSSEEFKSVLFFQTENCKDLVEEVFRFEGISPPRIIKNNEGDIRSHIREESAEIIIIELNESNNVTKDIDHISSLLPNNASVIVIGQEDAISTIRNLKTMGFYYLFWPASKLDIVDFLNNVRDNRRRNFGLGKKRSAKRVAIWGSKGGVGTSLIVAEISKELSEKRNSSCLVMDSSFLGGNLDIMLGLKQFKKRHIALGALTASLDETYASSMTQKVNDMLSLLAIESNELDNNQMKDYSRELSNELSHQVNFIIEDLSNSNISQSDFDYVALNIDTLIIVTEPSVSSVRAAANLIHQLEEKNSSVRCILIVNNVRPEKSATVSMSEIEKLLHKKINVECAYEQSLCDEILRGKSIYKQSFDISKKINIVTSLLLGEEPSLPKKNFLNRIFQSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z550</accession>
    <name>D0Z550_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Flp pilus assembly protein TadB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_000100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306847.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000100"/>
    <dbReference type="EnsemblBacteria" id="EEZ39084">
        <property type="protein sequence ID" value="EEZ39084"/>
        <property type="gene ID" value="VDA_000100"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4965">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1002350at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018076">
        <property type="entry name" value="T2SS_GspF_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00482">
        <property type="entry name" value="T2SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="81"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="103"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="247"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="283"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="7">
        <location>
            <begin position="139"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ39084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="306" mass="35199" checksum="630766FB4BE46751" modified="2010-01-19" version="1">MIYWIAIIFGGLIIIYLSLKNDQSSNEYFNEINQTILVSTMDEDRQAVNLTSLSDESFIQKLKRASNNTYNQLGDYPAVKLLIYFTLLLLFSFYINQNFIRENIFVVAFIIEIVGILWGISWLQKRERKKFEESFPDALNILTSAISSGESIIHAIVFVGKTLDGAVGNEFSLMGERLQLGESPDNVFRKSCMRFPYPSFQFFVITLRANMHRGGQLKDVMSRLNRIMFDARAIEKKKYALTSEARISAKIVAAIPFIFLFMLQYLSPENYEFVMFNPGGRPILYYVIISESIGITIVWLLMKGVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z563</accession>
    <name>D0Z563_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Outer membrane protein OmpU</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_000113</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell outer membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306886.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000113"/>
    <dbReference type="EnsemblBacteria" id="EEZ39097">
        <property type="protein sequence ID" value="EEZ39097"/>
        <property type="gene ID" value="VDA_000113"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1064531at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015288">
        <property type="term" value="F:porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00342">
        <property type="entry name" value="gram_neg_porins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033900">
        <property type="entry name" value="Gram_neg_porin_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13609">
        <property type="entry name" value="Porin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019441" evidence="3">
        <location>
            <begin position="23"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="Porin_4" evidence="4">
        <location>
            <begin position="12"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="308" mass="33340" checksum="1A8825ED0CE0C818" modified="2010-01-19" version="1">MSKNKIALGLLSLASVSGAANAANIYKTDDSTLDIGGRIEARAEHRDDNISDLSRVRLKIEGETKITDSVSGIAQFEQEFKDNSQKTRHLYAGIKSVIGNGTATLVYGKTDGSMSLVTDITDIQAAYGAIAADKYKVGKRIANSLAFDYMNENGTSFAANYAGAEGKDIGDFDNGFSIGASQSFGDTGLIAGIGYAKQEKVDKKEKSQLDYAIGYQYKKLYIGALYSARRVGDKEGDGYDVVTAYKINSTYKATVGFGELHFDKGDDSRAVNADITAKWNSHFRTYAAVNRDLVNKDTQGMLGARYDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z576</accession>
    <name>D0Z576_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">IncF plasmid conjugative transfer pilus assembly protein TraB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000035</name>
        <name evidence="4" type="ORF">VDA_000126</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000005">
        <property type="protein sequence ID" value="EEZ39050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000035"/>
    <dbReference type="EnsemblBacteria" id="EEZ39050">
        <property type="protein sequence ID" value="EEZ39050"/>
        <property type="gene ID" value="VDA_000035"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39110">
        <property type="protein sequence ID" value="EEZ39110"/>
        <property type="gene ID" value="VDA_000126"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3170">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005498">
        <property type="entry name" value="T4SS_VirB10/TraB/TrbI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03743">
        <property type="entry name" value="TrbI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="103"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="429"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="46"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="103"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="429"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="457" mass="50059" checksum="C4AEA75F3173C1CB" modified="2010-01-19" version="1">MLLFFGLCGLVFWLINKPKETFVPPSPDFEPVITEDFTDKDAKSALQAQQRTIIALEKSVSELKKERQRLSEQVATGLDRLEQRLNDNSEETERLINNNLDAFRDSATTDPSNSVTPSLDPFGSLDQYPQVPTAPRGYLDDHSLKDIPTTTRRGIQTFSYRWPKMASETTYRRTSDNYVPTGSFVTAVLMGAADANAGVNAQGDTAPIVFRTIHEGILPNGKRSRIKDCFVTASVYGEISSNRGIARLNRMSCIFDEDGEEDILDIPVRGTAFSFARNGMRGTPVMRNGKIIQMAGISGLFTGLGDTAKNASSSTITGPSGVVSTVDPSKALLNMGGSALENIGSKLADYYIKLAEQYHPIIELNPGSVVNLVFLEGFPLDPLMRDGYEQRLSAQEVPQSVGDMASQLMTNMMNPLAAQPTLPTNPLKQQLSAQLQQKANQFDATTQSPPQPVYSPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z593</accession>
    <name>D0Z593_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_000143</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Nucleoid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the histone-like protein H-NS family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306970.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000143"/>
    <dbReference type="EnsemblBacteria" id="EEZ39127">
        <property type="protein sequence ID" value="EEZ39127"/>
        <property type="gene ID" value="VDA_000143"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2916">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1911889at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009295">
        <property type="term" value="C:nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027444">
        <property type="entry name" value="H-NS_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037150">
        <property type="entry name" value="H-NS_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001801">
        <property type="entry name" value="Histone_HNS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027454">
        <property type="entry name" value="Histone_HNS_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00816">
        <property type="entry name" value="Histone_HNS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002096">
        <property type="entry name" value="HnS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00528">
        <property type="entry name" value="HNS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNS" evidence="9">
        <location>
            <begin position="86"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="DNA-binding region" evidence="6">
        <location>
            <begin position="111"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="77"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="23"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR002096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR002096-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ39127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="128" mass="14871" checksum="9CC5ADA981527344" modified="2010-01-19" version="1">MSETISVLLNLRTLRAQSRELTLEQLQEGLEKLTQVVNERVQEEEQLRAENREKEEKLETYRQLLLADGIDPEELIATMSTSKTNKSTRAPRPAKYRYTDENGQDKTWTGQGRTPKFLADKDLNDYLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5A4</accession>
    <name>D0Z5A4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC-type antimicrobial peptide transport system ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_000154</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306999.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000154"/>
    <dbReference type="EnsemblBacteria" id="EEZ39138">
        <property type="protein sequence ID" value="EEZ39138"/>
        <property type="gene ID" value="VDA_000154"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1136">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1181903at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="7"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="43"/>
            <end position="50"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="230" mass="25005" checksum="E14F318FE8BDFA43" modified="2010-01-19" version="1">MLSEPLVKLTNICKYYASGEAEVRALDGVDLTINRGEFLSILGPSGSGKSTLMNMLGCLDKPTHGKYQLGGQNVASLSANELASIRNQRIGFVFQSFNLLEYATALDNVALPLVYSDIKAKERRQRATRLLEQVGLGDRLDHKPNQLSGGQKQRVAIARALVNDPQIILADEPTGALDSKSGAEIEALFNQLHSEGRTLIIVTHDNALAKRTKRIITIKDGKVISDKAPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5E9</accession>
    <name>D0Z5E9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATPase_AAA_core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000056</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000005">
        <property type="protein sequence ID" value="EEZ39071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005307094.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000005.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39071">
        <property type="protein sequence ID" value="EEZ39071"/>
        <property type="gene ID" value="VDA_000056"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1106">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="318943at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13304">
        <property type="entry name" value="AAA_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase_AAA_core" evidence="1">
        <location>
            <begin position="24"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="364" mass="41640" checksum="CE340CD4BEA85AB6" modified="2010-01-19" version="1">MLQHIKIRNFRSFKRLDIDRLGRINLISGKNNAGKTALLEAFQLHVSNFAPNATHSILSEREEFFSKNASRDDLSPLKHFFYGHTIDSTNTPLTIESNINKQELQFGRYSLVKEDDKYQRQYDTFDIEDAKALSYDSPEDSYIFCASTLHERTIVGHLLNTESFRRNYLRSRLVKQDDTKINFVPSGNINPATLSELWDRISLTALEEHVVSGLQIIEPRITGITFVQASSRIRVPIVKLNHLSEPVTLRSLGDGMTRICHIILSLVNSANGTLLIDEFENGLHWSVQEQIWKVIFELSVKHNIQVIATSHSRDCIASFSKNWGTNQNIGSFYRMEVDGDGLIKAIGYNYEDLEDSIEFDVEVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5I1</accession>
    <name>D0Z5I1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000088</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000006">
        <property type="protein sequence ID" value="EEZ39033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005307199.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000006.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000088"/>
    <dbReference type="EnsemblBacteria" id="EEZ39033">
        <property type="protein sequence ID" value="EEZ39033"/>
        <property type="gene ID" value="VDA_000088"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031MZF">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2125988at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="187" mass="20190" checksum="54171F7316583139" modified="2010-01-19" version="1">MQYPVSTQINQQQTQEEKNMEQNTSNQAFFKNKQRGASLENFIFWMIAASLILVVIVGLYMKATSGARNMTVKSDVGVIIAASQQWGGNNKTGISMTKLCEAGSHYLTNEICGAAKNGTNANPYGGNYAIKVDPANPSRVQIDITGIDANYVNVVANDLAPLSFDNCRLADGCATLKKTGNSVTLTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5J4</accession>
    <name>D0Z5J4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">IncF plasmid conjugative transfer pilus assembly protein TraU</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000012</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000008">
        <property type="protein sequence ID" value="EEZ38986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005307263.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000008.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000012"/>
    <dbReference type="EnsemblBacteria" id="EEZ38986">
        <property type="protein sequence ID" value="EEZ38986"/>
        <property type="gene ID" value="VDA_000012"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502Z7SA">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1609287at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009649">
        <property type="entry name" value="TraU"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06834">
        <property type="entry name" value="TraU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019457" evidence="1">
        <location>
            <begin position="23"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ38986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="336" mass="37366" checksum="3902B87316FE4693" modified="2010-01-19" version="1">MTKPLLWALGFSLLMASNAASASGPACRARFMNPITDICWECIFPITLGSVPLIPSRHPDTPNPSLPISFCPKPPPIFMQVGLNIGYWEPYAITDVTRVPFCMVNLGFSLGGGMSQQIGGQNSYKKPGDSSSGAFYQAHWYKYPLIYWLQILQSSACMAMDNFDVGYLTELDPFWDDDELSFILNPEAILFGNPIAQLACVAEAVKTSTSFFLPIDALFWCMGSQGSAYPLTGNTGYRDTPMQSAVLMAERLNYKLHRQGIVWESLGVDGAVCVQHPMPILPKSRYRYQLSNVIPNPFNCYPYGTTTAIWESGHDNPVTGDNFGFVQWRKRNCVFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVJ4</accession>
    <name>D0YVJ4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">tRNA-dihydrouridine(16) synthase</fullName>
            <ecNumber evidence="7">1.3.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">U16-specific dihydrouridine synthase</fullName>
            <shortName evidence="7">U16-specific Dus</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">tRNA-dihydrouridine synthase C</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">dusC</name>
        <name evidence="11" type="ORF">VDA_001574</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>5,6-dihydrouridine(16) in tRNA + NAD(+) = H(+) + NADH + uridine(16) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:53380"/>
            <dbReference type="Rhea" id="RHEA-COMP:13543"/>
            <dbReference type="Rhea" id="RHEA-COMP:13544"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>5,6-dihydrouridine(16) in tRNA + NADP(+) = H(+) + NADPH + uridine(16) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:53376"/>
            <dbReference type="Rhea" id="RHEA-COMP:13543"/>
            <dbReference type="Rhea" id="RHEA-COMP:13544"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7 8">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the Dus family. DusC subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the dus family.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.-" evidence="7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298308.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001574"/>
    <dbReference type="EnsemblBacteria" id="EEZ40548">
        <property type="protein sequence ID" value="EEZ40548"/>
        <property type="gene ID" value="VDA_001574"/>
    </dbReference>
    <dbReference type="GeneID" id="57342367"/>
    <dbReference type="eggNOG" id="COG0042">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1710586at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017150">
        <property type="term" value="F:tRNA dihydrouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02801">
        <property type="entry name" value="DUS_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.225.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02043">
        <property type="entry name" value="DusC_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035587">
        <property type="entry name" value="DUS-like_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001269">
        <property type="entry name" value="DUS_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032886">
        <property type="entry name" value="DusC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042270">
        <property type="entry name" value="DusC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018517">
        <property type="entry name" value="tRNA_hU_synthase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11082:SF26">
        <property type="entry name" value="PTHR11082:SF26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01207">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006621">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01136">
        <property type="entry name" value="UPF0034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7 8" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 7 8" id="KW-0288">FMN</keyword>
    <keyword evidence="7" id="KW-0521">NADP</keyword>
    <keyword evidence="6 7 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 7 8" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="7" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Dus" evidence="10">
        <location>
            <begin position="5"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7 9">
        <location>
            <position position="98"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="200"/>
            <end position="202"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="224"/>
            <end position="225"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="site" description="Interacts with tRNA; defines subfamily-specific binding signature" evidence="7">
        <location>
            <position position="35"/>
        </location>
    </feature>
    <feature type="site" description="Interacts with tRNA" evidence="7">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <feature type="site" description="Interacts with tRNA" evidence="7">
        <location>
            <position position="176"/>
        </location>
    </feature>
    <feature type="site" description="Interacts with tRNA; defines subfamily-specific binding signature" evidence="7">
        <location>
            <position position="272"/>
        </location>
    </feature>
    <feature type="site" description="Interacts with tRNA; defines subfamily-specific binding signature" evidence="7">
        <location>
            <position position="274"/>
        </location>
    </feature>
    <feature type="site" description="Interacts with tRNA" evidence="7">
        <location>
            <position position="279"/>
        </location>
    </feature>
    <feature type="site" description="Interacts with tRNA; defines subfamily-specific binding signature" evidence="7">
        <location>
            <position position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR006621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR006621-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ40548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="314" mass="35416" checksum="94D732B0446BC3EF" modified="2010-01-19" version="1">MRVILGPMEGVLDHLMREILTDINDYDLCVTEFVRVVDRLFPNSVFYRLCPELHNGGKTRAGTPVRVQILGQDPNWMAENGRRAVELGSPGVDINFGCPAKLVNKSKGGAVLLKEPELIHQIVKSVRQAVDPTKPVTAKIRLGWDDPNHCFEIADAIAQAGADEITVHGRTKEDGYRAEEIKWDYIHQLQQHSPISIVANGEVWNYQDGQQCIATTGTQSLMVCRGAINLPNLGNVIKYNADHMPWTEVLDLLLHYSTFEIKGDKGLYYPNRIKQWFAYLRHEYPQAKALFADIRRHNKAQPIVDILTQARAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVJ9</accession>
    <name>D0YVJ9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0229 protein VDA_001579</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001579</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0229 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298319.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001579"/>
    <dbReference type="EnsemblBacteria" id="EEZ40553">
        <property type="protein sequence ID" value="EEZ40553"/>
        <property type="gene ID" value="VDA_001579"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2718">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="481720at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01232">
        <property type="entry name" value="UPF0229"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006698">
        <property type="entry name" value="UPF0229"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30510">
        <property type="entry name" value="PTHR30510"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04285">
        <property type="entry name" value="DUF444"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="47"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="423" mass="48839" checksum="43C29F8B7CD5280D" modified="2010-01-19" version="1">MAHFIDRRLNGKNKSTVNRQRFLRRHKQQIKESIADAVNKRSITDVDSGEDISIPSRDISEPSFHQGRGGQRDVVHPGNDQFIPGDRIDRPQGGAGQGGSGEGQASPDGEGQDEFVFQISKDEYLDLLFEDLELPNLQKNQMNQIVEWKTFRSGYKSQGVPSNIAIVKSLQNSLARRTAMSAGKRRQLRELEQALDLLFTTEPAQPLEEARIKEEIEVLRKKIRSVPFIDTFDLRYKNYERRPQPSSQAVMFCLMDVSGSMDQATKDIAKRFYILLYLFLNRTYKNVDVVFIRHHTQAKEVDEHEFFYSQETGGTIVSSALRLMDEIVKKRYSPDEWNIYAAQASDGDNWADDSPGCRELLNKEILPVTRYYSYIEITRRAHQTLWREYEALQASHDNFTMQNIRGVDDIFPVFRELFKKQVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVL9</accession>
    <name>D0YVL9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Putative NAD(P)H nitroreductase</fullName>
            <ecNumber evidence="2">1.-.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001588</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
        <text evidence="3">Binds 1 FMN per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the nitroreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.-.-.-" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298332.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001588"/>
    <dbReference type="EnsemblBacteria" id="EEZ40561">
        <property type="protein sequence ID" value="EEZ40561"/>
        <property type="gene ID" value="VDA_001588"/>
    </dbReference>
    <dbReference type="GeneID" id="57342350"/>
    <dbReference type="eggNOG" id="COG0778">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1847197at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02135">
        <property type="entry name" value="YdjA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.109.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029479">
        <property type="entry name" value="Nitroreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000415">
        <property type="entry name" value="Nitroreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026021">
        <property type="entry name" value="YdjA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00881">
        <property type="entry name" value="Nitroreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000232">
        <property type="entry name" value="YdjA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55469">
        <property type="entry name" value="SSF55469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2 3" id="KW-0288">FMN</keyword>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitroreductase" evidence="4">
        <location>
            <begin position="16"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="10"/>
            <end position="12"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="131"/>
            <end position="133"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR000232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000232-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="182" mass="19700" checksum="10A1BDBF2D051F1C" modified="2010-01-19" version="1">MDALTLLLNRRSLPRLAEPAPSGEALENILRAGLRAPDHGGLTPWRFIVSQGDGLQKLADILVSAAKADELDDFVVEKASNAPFRAPMVITVVAKVTSGHKVPVFEQHLSAGCATQAMQMAAVAQGFSGFWRTGSWAYHPVVREALGVQGEDMIVGFLYLGTPSCREAKVHEQDLAKFVEYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVN0</accession>
    <name>D0YVN0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Long-chain fatty acid transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_001611</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell outer membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the OmpP1/FadL family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001611"/>
    <dbReference type="EnsemblBacteria" id="EEZ40584">
        <property type="protein sequence ID" value="EEZ40584"/>
        <property type="gene ID" value="VDA_001611"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2067">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005017">
        <property type="entry name" value="OMPP1/FadL/TodX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35093">
        <property type="entry name" value="PTHR35093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03349">
        <property type="entry name" value="Toluene_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018674" evidence="8">
        <location>
            <begin position="39"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ40584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="430" mass="47133" checksum="050B0B493E79448D" modified="2010-01-19" version="1">MEDLNKKLNKYKRGSFMSIKKRYISLAIASLLSSQSYAAGFQVSEHSASGLGRAFAGEAAIADDASVIGRNPAAMTHFKQAEFSGALSVINPSIDIYDHTWDQGAEDVAPIAFVPAGYYVHPVNDQLAVGLAMFSNYGVTTDYPTDFNAGSLAGKTSLLTVNLNPSVAYKLTPQLSIGGGVSLVYGKAELNRHLGSLSIAVPDSNPSDKTISMEGDTWAWGWNIGAFYELNENNRFGLSYRSQVDLDFDGDFTDYLGAITGKPNNTITGSLSVPLPAIAEFSGFHQLNKQWAIHYSLQWTQYSKFKELRATSSECKPGYNGQSGVCLLKEEDYDDTYRWAIGTTYTLNPLWTLRAGFAFDEQAGKPTLSIPDTDRYWYSAGATYHYNQHLSFDAGFSFIYSSKATFTEDSSTFTSKGKAYLAAVQANYKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVT4</accession>
    <name>D0YVT4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GST N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002015</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002015"/>
    <dbReference type="EnsemblBacteria" id="EEZ40983">
        <property type="protein sequence ID" value="EEZ40983"/>
        <property type="gene ID" value="VDA_002015"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0695">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13417">
        <property type="entry name" value="GST_N_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="6"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="39" mass="4605" checksum="8B05806353FEECAA" modified="2010-01-19" version="1">MINGGGKRKVPCLRIEEDGKTEWMYESNDIIAYLEQRFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVU7</accession>
    <name>D0YVU7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Formate-dependent phosphoribosylglycinamide formyltransferase</fullName>
            <ecNumber evidence="3">6.3.1.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">5'-phosphoribosylglycinamide transformylase 2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Formate-dependent GAR transformylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">GAR transformylase 2</fullName>
            <shortName evidence="3">GART 2</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Non-folate glycinamide ribonucleotide transformylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Phosphoribosylglycinamide formyltransferase 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">purT</name>
        <name evidence="6" type="ORF">VDA_002028</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>ATP + formate + N(1)-(5-phospho-beta-D-ribosyl)glycinamide = ADP + H(+) + N(2)-formyl-N(1)-(5-phospho-beta-D-ribosyl)glycinamide + phosphate</text>
            <dbReference type="Rhea" id="RHEA:24829"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:143788"/>
            <dbReference type="ChEBI" id="CHEBI:147286"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Purine metabolism; IMP biosynthesis via de novo pathway; N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide from N(1)-(5-phospho-D-ribosyl)glycinamide (formate route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PurK/PurT family.</text>
    </comment>
    <dbReference type="EC" id="6.3.1.21" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299217.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002028"/>
    <dbReference type="EnsemblBacteria" id="EEZ40996">
        <property type="protein sequence ID" value="EEZ40996"/>
        <property type="gene ID" value="VDA_002028"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0027">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1677960at2"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00127"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043815">
        <property type="term" value="F:phosphoribosylglycinamide formyltransferase 2 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004644">
        <property type="term" value="F:phosphoribosylglycinamide formyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01643">
        <property type="entry name" value="PurT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003135">
        <property type="entry name" value="ATP-grasp_carboxylate-amine"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005862">
        <property type="entry name" value="PurT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02222">
        <property type="entry name" value="ATP-grasp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="SSF51246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01142">
        <property type="entry name" value="purT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1 3" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ATP-grasp" evidence="5">
        <location>
            <begin position="117"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="5'-phosphoribosylglycinamide binding" evidence="3">
        <location>
            <begin position="20"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="5'-phosphoribosylglycinamide binding" evidence="3">
        <location>
            <begin position="361"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>N(1)-(5-phospho-beta-D-ribosyl)glycinamide</name>
            <dbReference type="ChEBI" id="CHEBI:143788"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="158"/>
            <end position="163"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="193"/>
            <end position="196"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="265"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="277"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="284"/>
        </location>
        <ligand>
            <name>N(1)-(5-phospho-beta-D-ribosyl)glycinamide</name>
            <dbReference type="ChEBI" id="CHEBI:143788"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="354"/>
        </location>
        <ligand>
            <name>N(1)-(5-phospho-beta-D-ribosyl)glycinamide</name>
            <dbReference type="ChEBI" id="CHEBI:143788"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="391" mass="42538" checksum="B64600549B5B26C7" modified="2010-01-19" version="1">MLGTALTNSATRVLLLGSGELGKEVAIECQRLGVEVIAVDRYPNAPAMHVAHRSHVIDMLDGEALQQIIATEKPHYIVPEIEAIATDTLVELEKQGLNVVPTANATKLTMNREGIRRLAAETLSIPTSPYRFADTYQDFVDAIEFVGTPCVVKPIMSSSGKGQSVIKSEADYATAWQYAQEGGRAGQGRVIVEGFVEFDYEITLLTIRAVDGIHFCAPIGHRQEDGDYRESWQPQAMTEQALIAAQDVAAKVVDALGGYGLFGVELFVKGDQVLFSEVSPRPHDTGMVTLISQDQSEFALHVRAFLGLPIRHICQYGPSASAVVLAEGTSNAIQFSGLDQALIEPNTQVRLFGKPEIHGRRRLGVVLTRRTSTEDAITDAITASKQIKVHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVX0</accession>
    <name>D0YVX0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nitro_FeMo-Co domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001251</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297730.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001251"/>
    <dbReference type="EnsemblBacteria" id="EEZ40229">
        <property type="protein sequence ID" value="EEZ40229"/>
        <property type="gene ID" value="VDA_001251"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1433">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1829885at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009399">
        <property type="term" value="P:nitrogen fixation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003731">
        <property type="entry name" value="Di-Nase_FeMo-co_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036105">
        <property type="entry name" value="DiNase_FeMo-co_biosyn_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02579">
        <property type="entry name" value="Nitro_FeMo-Co"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53146">
        <property type="entry name" value="SSF53146"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0535">Nitrogen fixation</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitro_FeMo-Co" evidence="2">
        <location>
            <begin position="11"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="157" mass="16847" checksum="889F5C4647762251" modified="2010-01-19" version="1">MMMAVAVTGRHEVAGHFGKAAAFVVFDEQGQQVALVENHNTKAIGCKHKKRIQRQLSDLGVTQIVLGNIGQRSLARLLNAGFAVYQVPNRSELSDVLNEQVAKVPLLAPEQGRPCKREKGECGCGCGSKKETAPKVGTVMQPQGVIRGLKTLGGFKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVY6</accession>
    <name>D0YVY6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pyridoxine 5'-phosphate synthase</fullName>
            <shortName evidence="2">PNP synthase</shortName>
            <ecNumber evidence="2">2.6.99.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pdxJ</name>
        <name evidence="3" type="ORF">VDA_001265</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>1-deoxy-D-xylulose 5-phosphate + 3-amino-2-oxopropyl phosphate = H(+) + 2 H2O + phosphate + pyridoxine 5'-phosphate</text>
            <dbReference type="Rhea" id="RHEA:15265"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57279"/>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
            <dbReference type="ChEBI" id="CHEBI:58589"/>
            <dbReference type="EC" id="2.6.99.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; pyridoxine 5'-phosphate biosynthesis; pyridoxine 5'-phosphate from D-erythrose 4-phosphate: step 5/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homooctamer; tetramer of dimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PNP synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.99.2" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297752.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001265"/>
    <dbReference type="EnsemblBacteria" id="EEZ40243">
        <property type="protein sequence ID" value="EEZ40243"/>
        <property type="gene ID" value="VDA_001265"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0854">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1159993at2"/>
    <dbReference type="UniPathway" id="UPA00244">
        <property type="reaction ID" value="UER00313"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033856">
        <property type="term" value="F:pyridoxine 5'-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008615">
        <property type="term" value="P:pyridoxine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00003">
        <property type="entry name" value="PNPsynthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00279">
        <property type="entry name" value="PdxJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004569">
        <property type="entry name" value="PyrdxlP_synth_PdxJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036130">
        <property type="entry name" value="Pyridoxine-5'_phos_synth"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30456">
        <property type="entry name" value="PTHR30456"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03740">
        <property type="entry name" value="PdxJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63892">
        <property type="entry name" value="SSF63892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00559">
        <property type="entry name" value="pdxJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0664">Pyridoxine biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="1-deoxy-D-xylulose 5-phosphate binding" evidence="2">
        <location>
            <begin position="11"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="region of interest" description="3-amino-2-oxopropyl phosphate binding" evidence="2">
        <location>
            <begin position="215"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="45"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="72"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="193"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>3-amino-2-oxopropyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57279"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="20"/>
        </location>
        <ligand>
            <name>3-amino-2-oxopropyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57279"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>1-deoxy-D-xylulose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>1-deoxy-D-xylulose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>1-deoxy-D-xylulose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>3-amino-2-oxopropyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57279"/>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="2">
        <location>
            <position position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="243" mass="26484" checksum="7FCBFDC102E2EEC6" modified="2010-01-19" version="1">MSHILLGVNIDHVATLRNARGTRYPDPVHAAEIAERAGADGITVHLREDRRHITDRDVRILRETIQTRMNLEMAVTDEMVAIALEIKPEYVCLVPEKREELTTEGGLDVAGQLEKVKSATEKLTAAGIKVSLFIDADRLQIDAAKACGAPFIELHTGHYADATNECEQLAELKKIAAAASYAADLGIKVNAGHGLTYHNVSAIAAIPELYELNIGHSIMGRALFDGLSTAVADMRQLMLDARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW21</accession>
    <name>D0YW21_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative CinA-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001281</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001281"/>
    <dbReference type="EnsemblBacteria" id="EEZ40259">
        <property type="protein sequence ID" value="EEZ40259"/>
        <property type="gene ID" value="VDA_001281"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1546">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036653">
        <property type="entry name" value="CinA-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008136">
        <property type="entry name" value="CinA_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02464">
        <property type="entry name" value="CinA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142433">
        <property type="entry name" value="SSF142433"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00199">
        <property type="entry name" value="PncC_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CinA" evidence="1">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="79" mass="8503" checksum="CB565052CF80C5ED" modified="2010-01-19" version="1">MAEGALTNSLADISVAISGIAGPTGGTEEKPVGTVWFAWVDKQGWRKTMVCQFSGNRSQVRYQAITQAILGMLHHLAEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW99</accession>
    <name>D0YW99_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">UDP-N-acetylmuramate--L-alanine ligase</fullName>
            <ecNumber evidence="4 11">6.3.2.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">UDP-N-acetylmuramoyl-L-alanine synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">murC</name>
        <name evidence="15" type="ORF">VDA_001177</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Cell wall formation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>ATP + L-alanine + UDP-N-acetyl-alpha-D-muramate = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanine</text>
            <dbReference type="Rhea" id="RHEA:23372"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:70757"/>
            <dbReference type="ChEBI" id="CHEBI:83898"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 11">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the MurCDEF family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.8" evidence="4 11"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001177"/>
    <dbReference type="EnsemblBacteria" id="EEZ40155">
        <property type="protein sequence ID" value="EEZ40155"/>
        <property type="gene ID" value="VDA_001177"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0773">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008763">
        <property type="term" value="F:UDP-N-acetylmuramate-L-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00046">
        <property type="entry name" value="MurC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000713">
        <property type="entry name" value="Mur_ligase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005758">
        <property type="entry name" value="UDP-N-AcMur_Ala_ligase_MurC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01225">
        <property type="entry name" value="Mur_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01082">
        <property type="entry name" value="murC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 11" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6 11" id="KW-0132">Cell division</keyword>
    <keyword evidence="7 11" id="KW-0133">Cell shape</keyword>
    <keyword evidence="10 11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="5 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11 15" id="KW-0436">Ligase</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 11" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase" evidence="12">
        <location>
            <begin position="10"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_M" evidence="14">
        <location>
            <begin position="113"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="13">
        <location>
            <begin position="315"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="115"/>
            <end position="121"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEZ40155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="472" mass="51129" checksum="5EE86113CD2051AF" modified="2010-01-19" version="1">MVPEMRRVERIHFVGIGGAGMSGIAEVLLNEGYCISGSDLSANPVTDRLSGKGAQIFFGHAASNVEGASVVVVSTAISQENPELVAARELRIPVVRRAEMLAELMRYRHGIAIAGTHGKTTTTALVTQIYSEAGLDPTFVNGGLVKSAGTNARLGCSRYLIAEADESDASFLHLQPMVCVVTNIEADHMDTYGGDFEVLKQTFIDFLHNLPFYGLAVMCIDDPVVRELLPRVGRPMLTYGFSEDADVRLMDYQQCGQQGFFTIVRKDKPELKVTLNVPGRHNALNATAAVAVATEEGVDDDAIIRALAEFQGTGRRFDHLGEFETGNGTAMLVDDYGHHPSEVDVTIQAARAGWPDKRLVMVFQPHRYSRTRDLYDDFANVLEQVDVLLMLDVYAAGEAPIAGADGRALCRTIRGRGKLDPIFVANKEALPAALANIIQNDDLVLTQGAGDVGKIARQLAELKLDIAAMQGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWA7</accession>
    <name>D0YWA7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA gyrase inhibitor YacG</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">yacG</name>
        <name evidence="3" type="ORF">VDA_001185</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 1 zinc ion.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Interacts with GyrB.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA gyrase inhibitor YacG family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297592.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001185"/>
    <dbReference type="EnsemblBacteria" id="EEZ40163">
        <property type="protein sequence ID" value="EEZ40163"/>
        <property type="gene ID" value="VDA_001185"/>
    </dbReference>
    <dbReference type="GeneID" id="57339960"/>
    <dbReference type="eggNOG" id="COG3024">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2071775at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008657">
        <property type="term" value="F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00649">
        <property type="entry name" value="DNA_gyrase_inhibitor_YacG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005584">
        <property type="entry name" value="DNA_gyrase_inhibitor_YacG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36150">
        <property type="entry name" value="PTHR36150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03884">
        <property type="entry name" value="YacG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="17"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="37"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="69" mass="7799" checksum="852FA16A2ADB5CAB" modified="2010-01-19" version="1">MTEKKEAPVTVVKCPTCKEDVVWGEQSPFRPFCSKRCQLIDLGEWADEEKAIPGAPDMSDSDGWSEDMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWC7</accession>
    <name>D0YWC7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ABC-type dipeptide transport system component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001390</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297987.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001390"/>
    <dbReference type="EnsemblBacteria" id="EEZ40365">
        <property type="protein sequence ID" value="EEZ40365"/>
        <property type="gene ID" value="VDA_001390"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4166">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="162819at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030678">
        <property type="entry name" value="Peptide/Ni-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002741">
        <property type="entry name" value="MppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018626" evidence="1">
        <location>
            <begin position="23"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="domain" description="SBP_bac_5" evidence="2">
        <location>
            <begin position="96"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="609" mass="70270" checksum="3DFC3681C162951E" modified="2010-01-19" version="1">MMKPIVMTVAALGWLMIAPSWATTLPDDLKWQTNLDEPLFASPDAQFGGTFRTYIASFPQTFRVVGPDSNGAFRGWLVDYQPALVAKHPNTEAWLPNLATHWALADDHKTVYFRLNPAAKWSDGKPVTADDYLFMLQMMRSKDIVAPWYNEYYSKQIVDIVKFDDHTIAVKQAEPKNPDDLLYYSNLQPRPKHFYKVKTDKNSDGIDDNYVRRYNFKPEPVTGPYYLDKVKKGKSVTFRHVGQDWWGYQNPYYKHRYNVEKIRLTVIRDNDIARKHYEKGSLDAFNLVMPSLWHDKSNTEPYQKGYIEKFWGYNQTLQGAGGIWINTQKPLLNNIDVRKGLGFATDFDGMIEKVLRGDYVRQANGMGVGQGDYTNKDIQAPKFDLTKANEYFIKAGFDKFDAQGIRMNEKGERLSFAITYAYAEHTPRLAYLKEQAKQAGVEYTLNLVDGSSAFKYVLENKHQLSFHTMGSSEIPAYWEYLHSSNANQPQTNNFTNYASSDMDSLIMAYRNEFDVSKKKALSKEIQQIVADEALIIPGYMVPYTRVGYWRWMKYPTPAMTKKTEQLFSVGMNSDLGTYWIDEKIKKETLAAIKQNKSFKPKVIVDESYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWJ4</accession>
    <name>D0YWJ4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 10">Ribosomal RNA small subunit methyltransferase E</fullName>
            <ecNumber evidence="4 10">2.1.1.193</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">VDA_001236</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>S-adenosyl-L-methionine + uridine(1498) in 16S rRNA = H(+) + N(3)-methyluridine(1498) in 16S rRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42920"/>
            <dbReference type="Rhea" id="RHEA-COMP:10283"/>
            <dbReference type="Rhea" id="RHEA-COMP:10284"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74502"/>
            <dbReference type="EC" id="2.1.1.193"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the RNA methyltransferase RsmE family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.193" evidence="4 10"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297699.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001236"/>
    <dbReference type="EnsemblBacteria" id="EEZ40214">
        <property type="protein sequence ID" value="EEZ40214"/>
        <property type="gene ID" value="VDA_001236"/>
    </dbReference>
    <dbReference type="GeneID" id="57339886"/>
    <dbReference type="eggNOG" id="COG1385">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1490892at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006700">
        <property type="entry name" value="rRNA_ssu_MeTrfase-E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30027">
        <property type="entry name" value="PTHR30027"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04452">
        <property type="entry name" value="Methyltrans_RNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015601">
        <property type="entry name" value="MTase_slr0722"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00046">
        <property type="entry name" value="TIGR00046"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 10 11" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="8 10 11" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR015601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ40214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="243" mass="26989" checksum="DB2AE8B9B11C207A" modified="2010-01-19" version="1">MRIPRIYHPESLPSQGSVMLSDDAANHVGRVMRMQAGQEIMLFDGSNAEFPAIITNASKKNVEVEIQQRVECSIESPLNIHLGQVVSRGEKMEFTIQKSVELGVNTITPLISERCGVKLNGERFDKKLAQWQKIAIAACEQSGRNVVPEIRPIMKLEDWCAEEFSGLKLNLHPRAKYSINTLPTPVTDVRLLIGPEGGLSSDEIDMTENYNFDEILLGPRVLRTETAAMTAITALQVRFGDLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWL2</accession>
    <name>D0YWL2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Outer membrane protein A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">VDA_001503</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell outer membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpA family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001503"/>
    <dbReference type="EnsemblBacteria" id="EEZ40477">
        <property type="protein sequence ID" value="EEZ40477"/>
        <property type="gene ID" value="VDA_001503"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2885">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3637">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046930">
        <property type="term" value="C:pore complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015288">
        <property type="term" value="F:porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07185">
        <property type="entry name" value="OmpA_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006664">
        <property type="entry name" value="OMP_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006665">
        <property type="entry name" value="OmpA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036737">
        <property type="entry name" value="OmpA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000498">
        <property type="entry name" value="OmpA-like_TM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00691">
        <property type="entry name" value="OmpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01389">
        <property type="entry name" value="OmpA_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01021">
        <property type="entry name" value="OMPADOMAIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103088">
        <property type="entry name" value="SSF103088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51123">
        <property type="entry name" value="OMPA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0626">Porin</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012542322" evidence="12">
        <location>
            <begin position="16"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="OmpA-like" evidence="13">
        <location>
            <begin position="187"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEZ40477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="317" mass="33903" checksum="AAB792ECF3F3B323" modified="2010-01-19" version="1">MILPLALLVSAAANAATDNPFYAGARIGNAIYDTDHKGPNVDDANLAGGAFLGYQIAPWFAVEAGYTHLGSTTIKGTDAKFRTQGADIVGKYSYAINDKIDVFGKLGAYYYDVHTKNLADAKEHGWAGTAGVGAEYYLTNNLSTAVEYQYYNDVAGADIHFAGVSLAYHWGAPAPVVAEPVYVDQVSVETLEELKLAVPFAFDSTELSAGDRAKLAPFEQRLQAQDAAQIYVVGYTDSRGSEAYNQKLSVKRADAVAEALRSVMNVDGSRIIAEGRGESNPVASNDTAEGRAQNRRVEIISPSIDVETVTQVEQAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWM9</accession>
    <name>D0YWM9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Glucose-1-phosphate thymidylyltransferase</fullName>
            <ecNumber evidence="4 5">2.7.7.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_001520</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>alpha-D-glucose 1-phosphate + dTTP + H(+) = diphosphate + dTDP-alpha-D-glucose</text>
            <dbReference type="Rhea" id="RHEA:15225"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37568"/>
            <dbReference type="ChEBI" id="CHEBI:57477"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="EC" id="2.7.7.24"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the glucose-1-phosphate thymidylyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.24" evidence="4 5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298206.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001520"/>
    <dbReference type="EnsemblBacteria" id="EEZ40494">
        <property type="protein sequence ID" value="EEZ40494"/>
        <property type="gene ID" value="VDA_001520"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1209">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1004719at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008879">
        <property type="term" value="F:glucose-1-phosphate thymidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045226">
        <property type="term" value="P:extracellular polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02538">
        <property type="entry name" value="G1P_TT_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005907">
        <property type="entry name" value="G1P_thy_trans_s"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43532">
        <property type="entry name" value="PTHR43532"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01207">
        <property type="entry name" value="rmlA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transferase" evidence="6">
        <location>
            <begin position="2"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="290" mass="32359" checksum="B4DD2A4FF6CDF9C2" modified="2010-01-19" version="1">MKGIILAGGSGTRLYPITRGVSKQLLPIYDKPMIFYPLSTLMLAGIRDILIITTPEDNESFRRLLGNGADFGINLEFAIQPSPDGLAQAFLIGEEFIGDDSVCLVLGDNIFYGQSFSQTLLNAASREHGATVFGYQVKDPERFGVVEFDSEMKAVSIEEKPAEPKSNYAVTGLYFYDNRVVEMAKQVKPSERGELEITTLNEMYLNDGSLNVELLGRGFAWLDTGTHESLHEASSFVETIQNIQGLKVACLEEIAWRNGWLTSEQIQELAKPMMKNEYGQYLMRITSENK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWS1</accession>
    <name>D0YWS1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Acetate kinase</fullName>
            <ecNumber evidence="6">2.7.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Acetokinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ackA</name>
        <name evidence="8" type="ORF">VDA_001466</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>acetate + ATP = acetyl phosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:11352"/>
            <dbReference type="ChEBI" id="CHEBI:22191"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="6">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="6">Mg(2+). Can also accept Mn(2+).</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the acetokinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.1" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298112.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001466"/>
    <dbReference type="EnsemblBacteria" id="EEZ40440">
        <property type="protein sequence ID" value="EEZ40440"/>
        <property type="gene ID" value="VDA_001466"/>
    </dbReference>
    <dbReference type="GeneID" id="57339568"/>
    <dbReference type="eggNOG" id="COG0282">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="537106at2"/>
    <dbReference type="UniPathway" id="UPA00340">
        <property type="reaction ID" value="UER00458"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008776">
        <property type="term" value="F:acetate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006085">
        <property type="term" value="P:acetyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006082">
        <property type="term" value="P:organic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00020">
        <property type="entry name" value="Acetate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004372">
        <property type="entry name" value="Ac/propionate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000890">
        <property type="entry name" value="Aliphatic_acid_kin_short-chain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023865">
        <property type="entry name" value="Aliphatic_acid_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21060">
        <property type="entry name" value="PTHR21060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00871">
        <property type="entry name" value="Acetate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000722">
        <property type="entry name" value="Acetate_prop_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00471">
        <property type="entry name" value="ACETATEKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00016">
        <property type="entry name" value="ackA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01075">
        <property type="entry name" value="ACETATE_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01076">
        <property type="entry name" value="ACETATE_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 7" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton donor/acceptor" evidence="6">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="16"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="206"/>
            <end position="210"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="281"/>
            <end position="283"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="329"/>
            <end position="333"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="384"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="6">
        <location>
            <position position="178"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="6">
        <location>
            <position position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ40440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="398" mass="42850" checksum="23A4628CCE2F5D92" modified="2010-01-19" version="1">MSKLVLVLNCGSSSLKFAIIDPVSGEEHLSGLAECLGLPEARIKWKLDGKHEAQLGEGAAHEEALAFMVDTILASKPELKDNLGAIGHRIVHGGEQFTASALIDDVVLKGIEDAATFAPLHNPAHIIGIEAAKHNFPELKNVAVFDTAFHQSMPEEAFLYAIPYNLYKEHGIRRYGAHGTSHRFIARETAERLGKPQEELNIINCHLGNGASVCAIKNGQCVDTSMGLTPLEGLVMGTRCGDLDPAVMFHLHDKLGMSVDQINTMFTKESGLLGLTGVTSDCRFVEDNYGDKEEATRAMDVFCHRLAKYVAGYTATLDGRLDAIVFTGGIGENSGPIREMVLNRLAIFGIEVDGEANLKARFGGEGVITSANSRIPAMVVSTNEELVIAEDTALLANI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-06-02" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWU7</accession>
    <name>D0YWU7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DedD protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001539</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298239.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001539"/>
    <dbReference type="EnsemblBacteria" id="EEZ40513">
        <property type="protein sequence ID" value="EEZ40513"/>
        <property type="gene ID" value="VDA_001539"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3147">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1648036at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042834">
        <property type="term" value="F:peptidoglycan binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007730">
        <property type="entry name" value="SPOR-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036680">
        <property type="entry name" value="SPOR-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05036">
        <property type="entry name" value="SPOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110997">
        <property type="entry name" value="SSF110997"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51724">
        <property type="entry name" value="SPOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SPOR" evidence="2">
        <location>
            <begin position="138"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="222" mass="24116" checksum="6969D1C810184CC5" modified="2010-01-19" version="1">MASKFQNRLIGTVILVSVGVVVLPDIFDGQKEHYKEEFASIPLQPKAGEDEKYTTVPDPTEEQVALPEDPAEVTIDHSQSEHKQNADLSTTDTTPVVAVKPQSKPEPKPVVKPEPKPQPKPEPKPVVKPQPKPEKPAATTSGSWAIQLGVFSNVSNAQALVEKLQAVGYQAHLSPKNPKSGQYVRVIVGPETSKDKLTGQIGQLQKITGLKGRVFKFNPLNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWU9</accession>
    <name>D0YWU9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Yip1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_001541</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298241.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001541"/>
    <dbReference type="EnsemblBacteria" id="EEZ40515">
        <property type="protein sequence ID" value="EEZ40515"/>
        <property type="gene ID" value="VDA_001541"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502Z7KS">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1606932at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006977">
        <property type="entry name" value="Yip1_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04893">
        <property type="entry name" value="Yip1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="27"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="107"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="131"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="164"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="Yip1" evidence="6">
        <location>
            <begin position="8"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="199" mass="22174" checksum="BE3CF5383ADF3058" modified="2010-01-19" version="1">MIWEHVVGFYRNPIQEWHRVDKHHQSIFVSLLHIAIFALMPPVMAYLSSVYIGWDVGIGEPIYLTATSALNMSLAMYCTLIMGVIALAYLTYWMSHTFGSNPTYAQALELAAYTATPIFMASFAALIPHVWFLMLVGLCAVAYSVYLLYIGVPILMHIPKEQGFIYASSIVTSGLVLLVSIIASSVILWSYGMGPVFEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWV0</accession>
    <name>D0YWV0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001542</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001542"/>
    <dbReference type="EnsemblBacteria" id="EEZ40516">
        <property type="protein sequence ID" value="EEZ40516"/>
        <property type="gene ID" value="VDA_001542"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LysR_substrate" evidence="1">
        <location>
            <begin position="17"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="220" mass="25278" checksum="09CAF05115E8BC32" modified="2010-01-19" version="1">MQQLVDTTEHISEECKGAAGKLRIAAPSNVTKVMLQPMLNQFMVEHPAISIQLYMSNEPDQLDPTDWDVIFRVGPQRDSTLIARRINEVKDILVASPEYLKKNPAPKHAQDLHEHSLLKGNPLLRWRLTNHNGETVTITERGRFEASELNVVRRACCAGLGITLMPDVMLENYIESGEVVRILENWSANPRDVYLIYNHRDYQPEKLRLFIDFASHYFDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWX9</accession>
    <name>D0YWX9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Psp operon transcriptional activator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_001812</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298751.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001812"/>
    <dbReference type="EnsemblBacteria" id="EEZ40780">
        <property type="protein sequence ID" value="EEZ40780"/>
        <property type="gene ID" value="VDA_001812"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3829">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="123059at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002197">
        <property type="entry name" value="HTH_Fis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025944">
        <property type="entry name" value="Sigma_54_int_dom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014317">
        <property type="entry name" value="Transcription_activator_PspF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02954">
        <property type="entry name" value="HTH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00158">
        <property type="entry name" value="Sigma54_activat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01590">
        <property type="entry name" value="HTHFIS"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02974">
        <property type="entry name" value="phageshock_pspF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00688">
        <property type="entry name" value="SIGMA54_INTERACT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50045">
        <property type="entry name" value="SIGMA54_INTERACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="5">
        <location>
            <begin position="7"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="335" mass="38079" checksum="9B838B4EEC0D60F5" modified="2010-01-19" version="1">MQKPENIIGESESFLSALDQASRLASVNRPVLILGERGTGKELIAKRIHYLSKRWDQPLVTLNCAALSDGVIDSELFGHEAGSFTGAKGLHKGRFERAEQGTLFLDELATAPPSVQEKLLRVIEYGEYERVGGSKTYQSNVRLICATNENLPKLAHDGKFRADLLDRLAFDVIHLPPLRERLDDILPLAEHYAVRMCREMRFGYFAGFTLQAKKRLLQHSWPGNVRELKNAVERSVFRNGLEDEAVDNIILDPFTPPWHNTTTSIPTEVENQSSTLPQLPLDLRQWQQEQEKELIEQALEHAKHNQRKAAELLNLSYHQLRGLLRKYQLVGNSDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX04</accession>
    <name>D0YX04_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002057</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41025">
        <property type="protein sequence ID" value="EEZ41025"/>
        <property type="gene ID" value="VDA_002057"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031MZU">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="217" mass="22786" checksum="3750809F36FE0553" modified="2010-01-19" version="1">MLGNKIDQMIAALNNVMGVINGKLRLKADKSEVYLRNYLDDPLSTLGANASTANKLKVARTITLGRDAAGSVSFDGSGNVTLQVTIPALDDKADKVETLTPAQIDARIHQLIGVAPDVLDTFEELAKALGNDPNFAATMSAELAKKANASEVYTITAADAQFLTKRGKAADATLFGGNAPDHYATSGQISTLEQEIADGFTRLAASFNDAANTINGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXD3</accession>
    <name>D0YXD3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribonuclease T</fullName>
            <ecNumber evidence="4">3.1.13.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Exoribonuclease T</fullName>
            <shortName evidence="4">RNase T</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rnt</name>
        <name evidence="6" type="ORF">VDA_001612</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="4">Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RNase T family.</text>
    </comment>
    <dbReference type="EC" id="3.1.13.-" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298377.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001612"/>
    <dbReference type="EnsemblBacteria" id="EEZ40585">
        <property type="protein sequence ID" value="EEZ40585"/>
        <property type="gene ID" value="VDA_001612"/>
    </dbReference>
    <dbReference type="GeneID" id="57342310"/>
    <dbReference type="eggNOG" id="COG0847">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1985371at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016896">
        <property type="term" value="F:exoribonuclease activity, producing 5'-phosphomonoesters"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06134">
        <property type="entry name" value="RNaseT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00157">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Exonuclease_RNaseT/DNA_pol3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005987">
        <property type="entry name" value="RNase_T"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30231:SF2">
        <property type="entry name" value="PTHR30231:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01298">
        <property type="entry name" value="RNaseT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Exonuclease" evidence="5">
        <location>
            <begin position="18"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="4">
        <location>
            <position position="182"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="23"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="25"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="site" description="Important for substrate binding and specificity" evidence="4">
        <location>
            <position position="29"/>
        </location>
    </feature>
    <feature type="site" description="Important for substrate binding and specificity" evidence="4">
        <location>
            <position position="77"/>
        </location>
    </feature>
    <feature type="site" description="Important for substrate binding and specificity" evidence="4">
        <location>
            <position position="125"/>
        </location>
    </feature>
    <feature type="site" description="Important for substrate binding and specificity" evidence="4">
        <location>
            <position position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="221" mass="24672" checksum="5B0D28C969643AC8" modified="2010-01-19" version="1">MSQNNEFNSLKSRFRGYFPVVIDVETAGFNAQTDALLEICAVTLKMDDDGWLHPATTLHFHVTPFEGAILHKEALEFNGIRDPFSPLRGAVSEDTALKEIFKQIRKEQKNADCSRAIMVAHNANFDHSFVMAAAERAKLKRNPFHPFATFDTAALSGLALGQTVLAKACQTANIPFDNKEAHSALYDTERTAELFCKIVNKWKALGGWPLVDDETEENQND</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXH1</accession>
    <name>D0YXH1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ribonuclease E</fullName>
            <shortName evidence="5">RNase E</shortName>
            <ecNumber evidence="5">3.1.26.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rne</name>
        <name evidence="8" type="ORF">VDA_001678</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>Endonucleolytic cleavage of single-stranded RNA in A- and U-rich regions.</text>
            <dbReference type="EC" id="3.1.26.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="5">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5">Binds 2 Zn(2+) ions per homotetramer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation. Within the RNA degradosome, RNase E assembles into a homotetramer formed by a dimer of dimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Cell inner membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
            <orientation evidence="5">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the RNase E/G family. RNase E subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.12" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001678"/>
    <dbReference type="EnsemblBacteria" id="EEZ40649">
        <property type="protein sequence ID" value="EEZ40649"/>
        <property type="gene ID" value="VDA_001678"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1530">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009898">
        <property type="term" value="C:cytoplasmic side of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008995">
        <property type="term" value="F:ribonuclease E activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006402">
        <property type="term" value="P:mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00970">
        <property type="entry name" value="RNase_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019307">
        <property type="entry name" value="RNA-bd_AU-1/RNase_E/G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028878">
        <property type="entry name" value="RNase_E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004659">
        <property type="entry name" value="RNase_E/G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30001">
        <property type="entry name" value="PTHR30001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10150">
        <property type="entry name" value="RNase_E_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00757">
        <property type="entry name" value="RNaseEG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="5" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="5" id="KW-0820">tRNA-binding</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="S1 motif" evidence="7">
        <location>
            <begin position="36"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Required for zinc-mediated homotetramerization and catalytic activity" evidence="5">
        <location>
            <begin position="400"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="570"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="802"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1069"/>
            <end position="1095"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="570"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="680"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="818"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1072"/>
            <end position="1095"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="299"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="342"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="400"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="403"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ40649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="1095" mass="124078" checksum="94C15AC895D5C59F" modified="2010-01-19" version="1">MLINATQKEELRVALVDGQKLFDLDIESPGHESKKANIYKGRITRIEPSLEAAFVDYGAERHGFLPLKEIAKEYFPQDYSYQGRPNIKEVLKEGQEVIVQVDKEERGNKGAALTTFISLAGSYLVLMPNNPRAGGISRRIEGEERTQLKAALSTLELPHGMGLIVRTAGVGKSAEELEWDLNVLLNHWSAVKEAADAQPAPFLIHQESNVIARAIRDYLRRDIGEILIDSPKIFERARDHIKLVRPDFISRVKRYEGEVPLFSHYQIESQIESAFQREVRLPSGGSIVIDPTEALTSIDINSARATKGGDIEETALQTNLEAADEIARQLRLRDLGGLVVIDFIDMTPVRHQREVENRLREAVRMDRARVQIGRISRFGLLEMSRQRLSPSLAEASHHVCPRCTGTGVVRDNESLSLSILRLIEEEALKDNSSQVLAIVPVAIASYLLNEKRRSVQHIEKYHDVRVIIVPNSDMETPHFEVSRVREGEEQEALSYRIPKLLAAQREAETQEPVQPERVIKKREEPVLQGFTAPKEPAPIAKPAASKLAVQQPSIFNRIFSAIANFFSSHMSKKEEEQQPQENTNNRRNNNRRNDRNDNRRNDNRRNDNRRNDNRRNNRQQDSEQRDNRNNERQEKDNTRNNEQRQNNRRRNNERNNDRNNDKATKQDQRQQQQAEKPQKTQQQRQRDEEKELKRQARKEEIQAQKQQRRQEMQKEKTEKQNLEAQRENEEKTAKVKQRRQRRQLQKKVRIDDQQDVVEAIEVSSTATAEAKPSPLMEMGTAMAKAAQDEVKTQAVDMPTAPEMEEAEDQEDAPQRRNRRSPRHLRASGQRRRRMRDTRVEKPEHVTHEDVKMVPIDMMATDSVDALNDIENTVSIVEKPKSIQRRPATGVASPEMAMGKVWPRHTKPAVAAAEVIEETVVEPELDLAQAEAAMDNVLTPAIIETQQIAEVEAVETVVRTGVAMPELAMGKVFPMRAVEETQPVVSLTEEVEAEAPVLEQTEEVIVEAAPVVKEKEEAVIETTISLAPTKVKATMATNPRGFHATAPMAKAPAPVSMGHAETVAVAPTRDLATSRPAGSQVATNRASAPMTKPNFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXH5</accession>
    <name>D0YXH5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">50S ribosomal protein L32</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpmF</name>
        <name evidence="7" type="ORF">VDA_001682</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the bacterial ribosomal protein bL32 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298506.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001682"/>
    <dbReference type="EnsemblBacteria" id="EEZ40653">
        <property type="protein sequence ID" value="EEZ40653"/>
        <property type="gene ID" value="VDA_001682"/>
    </dbReference>
    <dbReference type="GeneID" id="57342237"/>
    <dbReference type="eggNOG" id="COG0333">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2092354at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00340">
        <property type="entry name" value="Ribosomal_L32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002677">
        <property type="entry name" value="Ribosomal_L32p"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044957">
        <property type="entry name" value="Ribosomal_L32p_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35534">
        <property type="entry name" value="PTHR35534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01783">
        <property type="entry name" value="Ribosomal_L32p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="SSF57829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01031">
        <property type="entry name" value="rpmF_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="56" mass="6207" checksum="0FC69DF9F0A15B76" modified="2010-01-19" version="1">MAVQKSKKSRAARGMRRSHDALTTAALSVDAVSGETHLRHHMTADGFYRGRKVINK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXK0</accession>
    <name>D0YXK0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Collagenase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001714</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298565.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40685">
        <property type="protein sequence ID" value="EEZ40685"/>
        <property type="gene ID" value="VDA_001714"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0826">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1264653at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071704">
        <property type="term" value="P:organic substance metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001539">
        <property type="entry name" value="Peptidase_U32"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01136">
        <property type="entry name" value="Peptidase_U32"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0176">Collagen</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="752" mass="84785" checksum="EE79111C08828EA5" modified="2010-01-19" version="1">MQNKFELLAPGGDLDSIKAAIAAGADAIYCGLDSFNARNRATNLTFDVLSGIIRLAHKNHCKIFLTLNIVVLDSEIPAVIRLLNKLVNTKVDGVILQDLGLFSIIKERFPTLDIHASTQINTHNDGQILFLKQLQASRVNLSRELNINEIKHLAQFGHQHDVLMEVFVHGSYCIGFSGLCYISSVKNGNSGNRGRCSQPCRDQYQTTAAGKDFPLNLKDNSAFSNMAELADAGVYSLKVEGRIKKSHYVYTVVDQWRQQIDRYLNQQPLLTDTKSLYTVFNRDFSSSYLQGDINKNMFIDNPRDNAVTHFTKVYQCTTPETINGVKQKLYDDKTEIIQTVEQVTANMDVSSLPLTIVLTGQEGEPLSISVTTPNHHFVLCSDSVLRDSNKQTLTHDMLEKRFQSLANEGEFEIVEFNTKGLNEALSVPFAELAQLKDQMGYRLNGNVAIVAPIEPPKPRNMVNHRKPTGIAPKLAVLISEPKDVTLGHGDEVALYYAMPEGLSMELETLVALFEQNPHLIPWFPAILIGENYQAAVEFIERVKPQQLVTNNNGIAYVAYQHEIDWIAGPYLNITNSFSLQCIADEFKAKGAFISNEINRKQINPMVCPENFELYYSIYHPLMMLMSRQCLFHQTVGCKKKRFDNKCLRKCDKSASILSLKEASFVLDKQRGTHNALYSQQNYMNLSAVTDFPDKFTRFMIDLRDIKTETQVNLDKPTLVNLFSRYIQGDMTAQEQLESGLIGTIHHQYKKGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXM5</accession>
    <name>D0YXM5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Acetyltransferase</fullName>
            <ecNumber evidence="2">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001766</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298661.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40734">
        <property type="protein sequence ID" value="EEZ40734"/>
        <property type="gene ID" value="VDA_001766"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0110">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1878940at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016407">
        <property type="term" value="F:acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039369">
        <property type="entry name" value="LacA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024688">
        <property type="entry name" value="Mac_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43017">
        <property type="entry name" value="PTHR43017"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12464">
        <property type="entry name" value="Mac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01266">
        <property type="entry name" value="Mac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Mac" evidence="3">
        <location>
            <begin position="4"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU367021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="205" mass="23174" checksum="71B4FE149A3E79F1" modified="2010-01-19" version="1">MDSKQRMHSQQVYFCDDSELVKEQLICLERLYDFNHSRPSHIEQRQALMKEMFASVGKDCYIEPPLHANWGKHTHLGDSVYANFNLTLVDDTHIYIGNHVMIGPNVTIATAGHPITPELRKQVSQFNIPVHIKDNVWLGAHCVVLPGVTIGENSVIGAGSIVTKDIPANVVAVGNPCKVLRPINERDREFYYQNRRFDDEVLAAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXM8</accession>
    <name>D0YXM8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Anaerobic C4-dicarboxylate transporter DcuC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_001769</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DcuC/DcuD transporter (TC 2.A.61) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001769"/>
    <dbReference type="EnsemblBacteria" id="EEZ40737">
        <property type="protein sequence ID" value="EEZ40737"/>
        <property type="gene ID" value="VDA_001769"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3069">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015556">
        <property type="term" value="F:C4-dicarboxylate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004669">
        <property type="entry name" value="C4_dicarb_anaerob_car"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018385">
        <property type="entry name" value="C4_dicarb_anaerob_car-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42002">
        <property type="entry name" value="PTHR42002"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03606">
        <property type="entry name" value="DcuC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00771">
        <property type="entry name" value="DcuC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="97"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="178"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="222"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="251"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="291"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="327"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="415"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ40737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="437" mass="45395" checksum="7749DBEB63C5022D" modified="2010-01-19" version="1">MKGYKAAGVLLTAGISLLIIAGILGHTILPAKVTSTGNLFTDSLEYVKYMLQYRGGGLGLQIMLLCGFASYMTHIGANNVVVKQFSKPLSFIKSPYILLVAAYIVACLMSLAVSSATGLGVLLMATLFPMMTAMGISRPAAAAVCASPAAIILSPTSGDVVVAAEKSGLPLHVFAVETVLPVSICAIIVMAVAAFFWNKYLDKKNNTPMEKVDISHMEVKAPSYYAILPFLPIIGVFVFNGETIPGLKLDIYTIVVLSITIGALVDYATNRLNGKLTLENLESCYAGMGDAFKGVVMLLVAAGVFAQGLMSVGAIDNLLHLADEAGAGGVALMLLLTALTVAAAIATGSGNAPFYAFVELAPQLAGKLGLSPAFLIIPMLQASNLGRTISPVSGVIVATSGMAQISPFDVVKRTVVPVIAGLITVIVGTMVLVPMYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXQ4</accession>
    <name>D0YXQ4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Aquaporin Z</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">aqpZ</name>
        <name evidence="11" type="ORF">VDA_001753</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 10">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="10">Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the MIP/aquaporin (TC 1.A.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298632.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001753"/>
    <dbReference type="EnsemblBacteria" id="EEZ40721">
        <property type="protein sequence ID" value="EEZ40721"/>
        <property type="gene ID" value="VDA_001753"/>
    </dbReference>
    <dbReference type="GeneID" id="57342156"/>
    <dbReference type="eggNOG" id="COG0580">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1744995at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015250">
        <property type="term" value="F:water channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00333">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01146">
        <property type="entry name" value="Aquaporin_Z"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034294">
        <property type="entry name" value="Aquaporin_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023743">
        <property type="entry name" value="Aquaporin_Z"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022357">
        <property type="entry name" value="MIP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45724">
        <property type="entry name" value="PTHR45724"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00783">
        <property type="entry name" value="MINTRINSICP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="SSF81338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00861">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00221">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0677">Repeat</keyword>
    <keyword evidence="7 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="81"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="131"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="164"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="205"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="NPA 1" evidence="10">
        <location>
            <begin position="63"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="NPA 2" evidence="10">
        <location>
            <begin position="186"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="site" description="Involved in tetramerization or stability of the tetramer" evidence="10">
        <location>
            <position position="20"/>
        </location>
    </feature>
    <feature type="site" description="Selectivity filter" evidence="10">
        <location>
            <position position="43"/>
        </location>
    </feature>
    <feature type="site" description="Selectivity filter" evidence="10">
        <location>
            <position position="174"/>
        </location>
    </feature>
    <feature type="site" description="Selectivity filter" evidence="10">
        <location>
            <position position="183"/>
        </location>
    </feature>
    <feature type="site" description="Selectivity filter" evidence="10">
        <location>
            <position position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ40721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="231" mass="23996" checksum="D1E7123E827C0864" modified="2010-01-19" version="1">MLKKLTAEFIGTFWLVLGGCGSAVLAAAFPDVGIGLLGVALAFGLTVVTMAYAIGHISGCHLNPAVTVGLWTGGRFPAAEVVPYILSQVLGAIAAAYTLYFIASGQPGYDLAVNGLAANGYGAHSPGHYDLASGFVIEVIMSFMFLFVILGVTHKLASPQMAGLAIGLALTLIHLISIPVTNTSVNPARSTGPALVVGDWAISQLWLFWVAPLIGAVLAGIVYRWLCPNQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXS7</accession>
    <name>D0YXS7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">OmpR/PhoB-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_002090</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002090"/>
    <dbReference type="EnsemblBacteria" id="EEZ41058">
        <property type="protein sequence ID" value="EEZ41058"/>
        <property type="gene ID" value="VDA_002090"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3710">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1807891at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="169"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="21"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="1">
        <location>
            <begin position="21"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="262" mass="29655" checksum="E54E0D0E7797D235" modified="2010-01-19" version="1">MLHWQSVLLEIIIILMNQSVIDIRQFGRFDVDLTNRIIKRRADSAEVKVSKSEILIFTYLAENKDKTIHRENLLKECWQGKVVTNNSLTVAIKNLRTALNEIDENNLIITEPKLGYAINGANLTHSVLSDLNDSDRNLEIQTLGKNPPANKREIPKKNIDIILPSKNHMVTLLFLLITYFIGMQYFSFIDEKSINGIPVIYDGIDLPNPVVNTIKQSQADGAAKWIAYPISGICSRYQLYGVIGDDFIDYSDKIKQGSCDVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXT0</accession>
    <name>D0YXT0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Riorf46 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002093</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41061">
        <property type="protein sequence ID" value="EEZ41061"/>
        <property type="gene ID" value="VDA_002093"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2801">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1637053at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="2">
        <location>
            <begin position="128"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="408"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="454" mass="53229" checksum="4EE58DA4DBA38D8A" modified="2010-01-19" version="1">MLLTMTDNELLRIKVIQDICDKRLTGVEAAHLLNLSPRQVYRLVKRFIEFGASGLVSLQRGRPGNHRYDENVKLQTLAILYEHYTDFGPTLAHEKLTERHNIHVSVETIRQWMIADGLWVPHTKRKPRVYQPRYRRDCLGELIQIDGSHHDWFEGRSNKCCLLVFIDDATGKLMNLRFSETESAFDYMVATREYLEQHGKPTAFYSDRHAVFHVSKRDAKTERLTQFGRVLHDLNIELICANSSQAKGRVERANKTLQDRLVKEMRLQGIDTIEQANVWLPDFIADFNRRFAKPAKYPKDMHRPVREMTDELNDIFAWQELRKLSKSLTFQYDKVVYLIDPTEENQRLINQVVKVLDRPDGTIAIQYGQRKLTFKVFDKLTDIDQGQIVDNKRLGAVLKFAQEKQQEFEQQQTRNRSKKAPTRTAQQRAIRQLEAINPVLVHYEQFKPSTRKKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY04</accession>
    <name>D0YY04_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Hypothetical DNA-binding response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_002167</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299578.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002167"/>
    <dbReference type="EnsemblBacteria" id="EEZ41135">
        <property type="protein sequence ID" value="EEZ41135"/>
        <property type="gene ID" value="VDA_002167"/>
    </dbReference>
    <dbReference type="GeneID" id="57341692"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1020672at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="2"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="126"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="126"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="225" mass="25393" checksum="04F04B5F882E74A1" modified="2010-01-19" version="1">MKILVIEDDNTTRDFVVQGLIEHGYVVDEASDGHQGLMMATSCEYSLIILDRMLPMLDGLKVLAAIRATENSTPVMILSAMDSVEERVVGLTAGSDDYLIKPFALAELIARAEILIKRHHATTQVATEYVYADLKLDLKSHRVWRGNRVINLQQKEFLLLQYLMGHAESVVSRMSLFESVWNYHFDPKTNIIDVHIANLRKKLDAEGEVSLIHTVRGAGYVLRQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY19</accession>
    <name>D0YY19_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative ATP-dependent helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002182</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002182"/>
    <dbReference type="EnsemblBacteria" id="EEZ41150">
        <property type="protein sequence ID" value="EEZ41150"/>
        <property type="gene ID" value="VDA_002182"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1061">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="SSF57829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="1">
        <location>
            <begin position="40"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="2">
        <location>
            <begin position="263"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="603" mass="68557" checksum="1B90A19DD8AC289D" modified="2010-01-19" version="1">MTIAGSTGYIYTVAVVILKSRILMYTLRPYQQDSVNATIHYFRKHNTPAVLVLPTGAGKSLVVAELARIARGRVLVLTHVKELVEQNHAKYESYDLKAAIFSAGLGRKETDQQVVFASVQSMANGLDKFTKQFSLLVIDECHRVPDDENSAYRKVIKHVQEVNPNIKILGLTATPYRLGMGWIYKYHTRGQVKTEQERFFRDCIFELPIRYLLDEGFLTEPKMMDMAVIGYDFSSITPSATGHYQTADLDDVIEKSARATPIIIEQVIDYAKDRKGVMIFASTVTHAQEIMGYLAAENAALVVGDTPIEERDRIINDFKDQKIKYLVNVSVLTTGFDAPHVDLIAILRPTESISLYQQIVGRGLRLSEGKKDCLVLEYAGNCYDLYQPEVGDPKPNSDSEVIMVPCPACGFNNSFWGKLDPAGFLIEHYGRRCQGYFEDDETGEREECGYRFRAKYCEECGADNDIAARRCHLCNAVMVDPDKKLREALKLKDAMIMKINDMRLEAGKNQYGKPQLKVIYESDEGSEISEVWTLSNKTQKQEFLKKFINPHLVDRHRPFLDTAPTKVANNEHRLRPPEIIIARKSGRFWAIRDKLFDIDQYQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY79</accession>
    <name>D0YY79_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative phospholipase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002242</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299721.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="SMR" id="D0YY79"/>
    <dbReference type="STRING" id="675817.VDA_002242"/>
    <dbReference type="EnsemblBacteria" id="EEZ41210">
        <property type="protein sequence ID" value="EEZ41210"/>
        <property type="gene ID" value="VDA_002242"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3240">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1247435at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001087">
        <property type="entry name" value="GDSL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00657">
        <property type="entry name" value="Lipase_GDSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019880" evidence="1">
        <location>
            <begin position="21"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="405" mass="45936" checksum="9C9D7BC4D30D3AED" modified="2010-01-19" version="1">MKKSVLTLTLALLCSQNVFAQDQPTLDPGKSTYTSVRCWYRSGATHDEASTEWKWAKNSDGSYYTVPGYWYSSVSPVNMFFTDVGQETIKQQCKQTLGIDHNAADITYFASDMRYSFNHSFWTNDKSNQTGKINKIVSFGDSISDTGNIFNAFQWRFPNPNSWFLGHFSNGFVWTEYLAQEKHLPLYTWAVGGAAGETEYGFLSGIHDQVNSYLQYMTMAKNYNPQNTLFTIEFGLNDFINYNRTVAEVSKDFTTALTTLFKNGAENIVVLTLPDASIAPQFKYSTPEHAQEVSAKIKQFNQYVTTEAMRFRMEGHNVALFDSMALFNDMTTTPAKYGFHNIKDACLNINRSSSKDYLMSHALTNDCASYGSDSYMFWGVTHPTTHTHHILAEEVAKKVSSQFNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY81</accession>
    <name>D0YY81_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_002244</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299723.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002244"/>
    <dbReference type="EnsemblBacteria" id="EEZ41212">
        <property type="protein sequence ID" value="EEZ41212"/>
        <property type="gene ID" value="VDA_002244"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3829">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5001">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004673">
        <property type="term" value="F:protein histidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029151">
        <property type="entry name" value="Sensor-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13188">
        <property type="entry name" value="PAS_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103190">
        <property type="entry name" value="SSF103190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="298"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="4">
        <location>
            <begin position="459"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="5">
        <location>
            <begin position="531"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="7">
        <location>
            <begin position="614"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="6">
        <location>
            <begin position="755"/>
            <end position="1008"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ41212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="1021" mass="117633" checksum="D74AFCAA50A6FA29" modified="2010-01-19" version="1">MKQVLIRFIGILLPLIAIVATASWYFYQQDVAQLQERVKEKEHNYHSSLMQIHKLHFKSTIHDLTYLSGKIQPQHGNKLSVEEIRKTFNQLMINTPEYFSIALLDKKGYPIIQTNSLKSQQNLPPQDIYRHYQTIIKNIPERSILVSPFLYYENEILYNFMLTIGHNKFSSILLSYRLNTFLNDFSKDYSWTNGKNFILDENGNLIVKAENELWPYSMTKEKFSDLYKKEWDLIKNNKQGQFTIEGQLFTFTNFSLINITASNSNIPSVNFPWVIITKTDIHQEVNHLLYSQQRIIKIIAFVVFIMSLFSACIVLAWHFSQQLLYEKKLRKERDNILDRYSSVIRNTADGLILINRKKQIKSLNYAACSIFNITTDSVGQSILSITTDKTVTAEILRLFNLVSAEKPNSKHTIFKAKTILNTISIRHIELMVSKIDSTNQDEFLFNIKDITYWVQRENKIRNLSQVIEQSDDGIVIISFDGIIEYVNKSFELAKNKRSYELVGTKAEVLLEPYNIPDLELEQLHKKIQRGETIQYIVDYFDNNHNTIYEHKKISPIKNNNGDITHYVSITRNITEQIIAEEKLKRLAHYDDKTSLPNRVHLTNKIANYIQSSETPAILLDIDLDNFKTVNETLGMECGDEILLVIAQRLQIFAQSGIIARVSGDEFVLFLTNLAVIPDFQRFCQQIHEYISQPIQIQHKSLSINISIGIARYPQDATTTDSLIKYANIALYEAKDRGRNRDCYFDIEMAERSTKQLQLEMQLRESLGTERYELFYQPKVDTRTHKLVGAEALLRWRDQYGKLVSPTDVIPILELSGLIIPVGEQLITQACMTLKRWQEQGLQLHLALNLSAKQLEDSDIVETFERSIILTGCDPSLLQVELTESILMTDVKLALDTLTRLQTLGIKIAIDDFGTGYSSLAYLHTFPIHILKVDRSFVKDLPFCADSITISKAIVELAHSLNLQVVAEGVEDKHQAAFLNSINVDELQGFYFGKPMPIQDFETHFLPNNSKNHSPCSESAKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYC8</accession>
    <name>D0YYC8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Membrane-fusion protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002291</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299800.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002291"/>
    <dbReference type="EnsemblBacteria" id="EEZ41259">
        <property type="protein sequence ID" value="EEZ41259"/>
        <property type="gene ID" value="VDA_002291"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0845">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1174564at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039562">
        <property type="entry name" value="MFP_biotin_lipoyl_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13533">
        <property type="entry name" value="Biotin_lipoyl_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin_lipoyl_2" evidence="2">
        <location>
            <begin position="49"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="64"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="319" mass="34872" checksum="24D1565AE46DCF3E" modified="2010-01-19" version="1">MYKNLAFILSISILVSLTGCNDSTSHQALGTLERDTVRLTATSNEIIRKMPIQEGQKVKAGDLLVQLDDQMQKAALEKARAEQGKAKAYLQRLLNGERPEDIATAQAHLAKSQANLQDAKQNFQRVAKLVKRKVMTQADLDNAQAQLSAAIADVTANQETLDKLVQGTRIEDIAQAEQALKASQAEVALQQQKLSDLTVVATRDGILDSLPYHVGSRVPLNGVVAIVEANTAPYAQVYIPEPYRVHLKAGDKLTVHVDGLDTPFQGTLRWIATESTFTPYYALNAEDRARLVYLAKIDLPTDAVDLPSGVPAQVDMPHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYG6</accession>
    <name>D0YYG6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5 6">50S ribosomal protein L20</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplT</name>
        <name evidence="7" type="ORF">VDA_002329</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the bacterial ribosomal protein bL20 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299885.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002329"/>
    <dbReference type="EnsemblBacteria" id="EEZ41297">
        <property type="protein sequence ID" value="EEZ41297"/>
        <property type="gene ID" value="VDA_002329"/>
    </dbReference>
    <dbReference type="GeneID" id="57341483"/>
    <dbReference type="eggNOG" id="COG0292">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1932144at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07026">
        <property type="entry name" value="Ribosomal_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1900.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00382">
        <property type="entry name" value="Ribosomal_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005813">
        <property type="entry name" value="Ribosomal_L20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035566">
        <property type="entry name" value="Ribosomal_protein_L20_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10986">
        <property type="entry name" value="PTHR10986"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00453">
        <property type="entry name" value="Ribosomal_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00062">
        <property type="entry name" value="RIBOSOMALL20"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74731">
        <property type="entry name" value="SSF74731"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01032">
        <property type="entry name" value="rplT_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00937">
        <property type="entry name" value="RIBOSOMAL_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="117" mass="13476" checksum="DF618FF64D051474" modified="2010-01-19" version="1">MPRVKRGVQARARHKKVLKQAKGYYGARSRVYRVAFQAVTKAGQYAYRDRRQKKRTFRQLWIARINAAARQNGMSYSRFINGLKKASIEIDRKILADIAVFDKATFTVLVEKAKAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYH2</accession>
    <name>D0YYH2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Riboflavin synthase alpha chain</fullName>
            <ecNumber evidence="4">2.5.1.9</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_002335</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.5.1.9" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299903.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002335"/>
    <dbReference type="EnsemblBacteria" id="EEZ41303">
        <property type="protein sequence ID" value="EEZ41303"/>
        <property type="gene ID" value="VDA_002335"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0307">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1276859at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004746">
        <property type="term" value="F:riboflavin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00402">
        <property type="entry name" value="Riboflavin_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023366">
        <property type="entry name" value="ATP_synth_asu-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001783">
        <property type="entry name" value="Lumazine-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026017">
        <property type="entry name" value="Lumazine-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21098">
        <property type="entry name" value="PTHR21098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00677">
        <property type="entry name" value="Lum_binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000498">
        <property type="entry name" value="Riboflavin_syn_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00187">
        <property type="entry name" value="ribE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51177">
        <property type="entry name" value="LUMAZINE_BIND"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="Lumazine-binding" evidence="2">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="Lumazine-binding" evidence="3">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="repeat" description="Lumazine-binding" evidence="2">
        <location>
            <begin position="98"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="Lumazine-binding" evidence="3">
        <location>
            <begin position="98"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="202" mass="22301" checksum="36D0B6491D75A85C" modified="2010-01-19" version="1">MFTGIVQSTAPVVAIDKKLNFQTHTILMPEHLLDGLEIGASVAHNGCCLTVTKIEGRHISFDLMQETLKVTNLGLVHVGDEVNIERAAKFGDEIGGHSMSGHIICTAKVLDVIESENNRQVWFSMPEHLMKYVFTKGYIGIDGISLTIGDVVDNSFNVNLIPETLTRTNLKSRQVGDVINIEIDPQTQAVVDTVERMMAQRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYI6</accession>
    <name>D0YYI6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 9">Alpha-acetolactate decarboxylase</fullName>
            <ecNumber evidence="4 9">4.1.1.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_002349</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>(2S)-2-acetolactate + H(+) = (R)-acetoin + CO2</text>
            <dbReference type="Rhea" id="RHEA:21580"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15686"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:58476"/>
            <dbReference type="EC" id="4.1.1.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Polyol metabolism; (R,R)-butane-2,3-diol biosynthesis; (R,R)-butane-2,3-diol from pyruvate: step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the alpha-acetolactate decarboxylase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.5" evidence="4 9"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002349"/>
    <dbReference type="EnsemblBacteria" id="EEZ41317">
        <property type="protein sequence ID" value="EEZ41317"/>
        <property type="gene ID" value="VDA_002349"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3527">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1445885at2"/>
    <dbReference type="UniPathway" id="UPA00626">
        <property type="reaction ID" value="UER00678"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047605">
        <property type="term" value="F:acetolactate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045151">
        <property type="term" value="P:acetoin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd17299">
        <property type="entry name" value="acetolactate_decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005128">
        <property type="entry name" value="Acetolactate_a_deCO2ase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35524">
        <property type="entry name" value="PTHR35524"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03306">
        <property type="entry name" value="AAL_decarboxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001332">
        <property type="entry name" value="Acetolac_decarb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01252">
        <property type="entry name" value="acetolac_decarb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0005">Acetoin biosynthesis</keyword>
    <keyword evidence="6 9" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="8 9 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR001332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ41317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="226" mass="25164" checksum="431106D0B114CF71" modified="2010-01-19" version="1">MMSALIAGLYEGDFTIGQLLEHGNFGIGTFDDLDGEMIVLGNEVYQLTSIGDVHLVDKAMTTPFASVVDFQPTETKALTQLTKQELEALLEQEGLVANNAINAIRMTGTFSYVKTRTVPAQHRPYPPMVEVVKHQPVFELEQVSGVMIGFKIPDYMIGINVPGYHFHFISDDRTQGGHVSDFVLAQGTLETEIFKDFHLRMPASHEFDVADLHPEDLKEAIHTTEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYN4</accession>
    <name>D0YYN4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Tryptophan synthase alpha chain</fullName>
            <ecNumber evidence="7">4.2.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">trpA</name>
        <name evidence="9" type="ORF">VDA_002397</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + L-serine = D-glyceraldehyde 3-phosphate + H2O + L-tryptophan</text>
            <dbReference type="Rhea" id="RHEA:10532"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
            <dbReference type="ChEBI" id="CHEBI:58866"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.2.1.20"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 5/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Tetramer of two alpha and two beta chains.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the TrpA family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.20" evidence="7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300020.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002397"/>
    <dbReference type="EnsemblBacteria" id="EEZ41365">
        <property type="protein sequence ID" value="EEZ41365"/>
        <property type="gene ID" value="VDA_002397"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0159">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="912786at2"/>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00044"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004834">
        <property type="term" value="F:tryptophan synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04724">
        <property type="entry name" value="Tryptophan_synthase_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00131">
        <property type="entry name" value="Trp_synth_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018204">
        <property type="entry name" value="Trp_synthase_alpha_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002028">
        <property type="entry name" value="Trp_synthase_suA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43406">
        <property type="entry name" value="PTHR43406"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00290">
        <property type="entry name" value="Trp_syntA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00262">
        <property type="entry name" value="trpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00167">
        <property type="entry name" value="TRP_SYNTHASE_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5 7" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="6 7 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="49"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="270" mass="28668" checksum="8A8691A753E014EF" modified="2010-01-19" version="1">MDRYSLLFDRLGARNEGAFVPFVTIGDPNPTLSLQIIDTLVESGADALELGIPFSDPLADGPTIQGATIRALTAGTTPPVCFESLKQIRLKYPELPIGLLMYANLVFAAGLDNFYHQCAEAGIDSVLIADVPLHASAEFRQAAKKHGIDAIFIAPPNADEETLKMVAEYGSGYTYLLSRAGVTGAETKAGMPVDHLLKSLKDHHAPPALLGFGISSPEQVSDAIKAGSAGAISGSAVVKIIETHLEQPEELLKAMSHFIQTMKAATKNSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYN9</accession>
    <name>D0YYN9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sodium-dependent transporter putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_002402</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300026.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002402"/>
    <dbReference type="EnsemblBacteria" id="EEZ41370">
        <property type="protein sequence ID" value="EEZ41370"/>
        <property type="gene ID" value="VDA_002402"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0733">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="376209at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000175">
        <property type="entry name" value="Na/ntran_symport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037272">
        <property type="entry name" value="SNS_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00209">
        <property type="entry name" value="SNF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00176">
        <property type="entry name" value="NANEUSMPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161070">
        <property type="entry name" value="SSF161070"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50267">
        <property type="entry name" value="NA_NEUROTRAN_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0769">Symport</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="42"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="87"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="144"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="174"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="214"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="250"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="309"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="351"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="384"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="421"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ41370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="444" mass="48489" checksum="9826823D1CB311A1" modified="2010-01-19" version="1">MAGQSRAQFSSRLGFILAAAGSAVGLGNIWGFPTQAASNGGAVFLLVYLVMVFALAYPLLVAELTIGRYGHANPIKSIRAIWPKQPVIAAVLGIAGMVAVSMILSFYAIVAGWLFGYLVGPIANYVGLTSVGDWLENFSTSRNLVLMILFMLLTILVVRNGVADGIERWSTRLMPVLFVLFLLLVGYIFTQHGAMEGLKMYLVPDMSHFSSDLVVSAMGQAFFSLSLGVCSMMVYGSYLKKEVNLPKTAAQVALLDTSVAFVAGLLILPAMFVASNNGVEIYNDAGELLSSDTLVFSVLPAMFDTMGTVGFIVGILFFVLMVIAALTSSISMLEVPVSCATEELKQDRHIAVWWIGGLITLFSAIIVFNFGDLFGLVISLTTEYAQPILGMLFALLVGWVWKRDQVLQEIKSGYPDLEHSLFWKIWPWYVRVVCPLLMLWVFFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYU1</accession>
    <name>D0YYU1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002454</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300123.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002454"/>
    <dbReference type="EnsemblBacteria" id="EEZ41422">
        <property type="protein sequence ID" value="EEZ41422"/>
        <property type="gene ID" value="VDA_002454"/>
    </dbReference>
    <dbReference type="GeneID" id="57341327"/>
    <dbReference type="eggNOG" id="ENOG5033CMH">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2013618at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021879">
        <property type="entry name" value="Ribosomal_S4Pg"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11993">
        <property type="entry name" value="Ribosomal_S4Pg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="177" mass="19714" checksum="65F86EBBBDC8ED6B" modified="2010-01-19" version="1">MTAVHTLDKAQLINEIQLGNQLGHAVEQGRRSDFALMLALLSPDFLENTPVDHIDNKPVTDSQLRGYFELQDSRPLTTSEFCYERGAVQAEAFHQGGLASCRLMDGLQPIALTFPPQDTKGMPEELYHNLSGHERRKLPPTEIIVPESSPQRLYGALVQAKRFAEMQAQAPQIYATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYW9</accession>
    <name>D0YYW9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Long-chain-fatty-acid--CoA ligase</fullName>
            <ecNumber evidence="3">6.2.1.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002482</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="6.2.1.3" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300176.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002482"/>
    <dbReference type="EnsemblBacteria" id="EEZ41450">
        <property type="protein sequence ID" value="EEZ41450"/>
        <property type="gene ID" value="VDA_002482"/>
    </dbReference>
    <dbReference type="GeneID" id="57341296"/>
    <dbReference type="eggNOG" id="COG0318">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="961884at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004467">
        <property type="term" value="F:long-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="29"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="2">
        <location>
            <begin position="470"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="564" mass="63162" checksum="CF54DD0411D6163A" modified="2010-01-19" version="1">MDKVWLSRYPEDVPAEINPDMYSSLVDMFEQSVQKYADQTAFINMGQVMTFRKLEERSRAFAAYLQNDLKLQKGDRVAVMMPNLLQYPIAIFGILRAGCVVVNVNPLYTPRELEHQLNDAGAKAIVIVSNFAHTLEAVVKDTSVEHVILTRLGDQLSRPKGTLVNFVVKYIKKMVPKYHLPHATSMRMALRKGRRMQYVKPFISGEDMAFLQYTGGTTGVAKGAMLTHHNMVSNVMQAKGAYGPVLTEGRELIVTALPLYHVFALTVNCLLILEMGGQNLLITNPRDIPTFIKELQRYPFTAITGVNTLFNALVNNEDFHELDFSNLRLSVGGGMAVQRAVAEKWQNITGNYLLEGYGLTECSPLVAAYPYDLTQYNGSIGLPVPSTEVRLIDDEGNEVGMDGTGELQVRGPQVMKGYWQRPEATKEVLTDDGWLSTGDIVRFDDDGFMHIVDRKKDMILVSGFNVYPNEIEDVVALHGKVMEVAAIGQAHDVSGEIVKLCVVKRDPSLTREELIAHCREHLTGYKIPKIVEFHEELPKSNVGKILRRVLREESDKKLAEKTNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-08-12" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ13</accession>
    <name>D0YZ13_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Recombination protein RecR</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">recR</name>
        <name evidence="9" type="ORF">VDA_002526</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the RecR family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002526"/>
    <dbReference type="EnsemblBacteria" id="EEZ41494">
        <property type="protein sequence ID" value="EEZ41494"/>
        <property type="gene ID" value="VDA_002526"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0353">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01025">
        <property type="entry name" value="TOPRIM_recR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00017">
        <property type="entry name" value="RecR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000093">
        <property type="entry name" value="DNA_Rcmb_RecR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023627">
        <property type="entry name" value="Rcmb_RecR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023628">
        <property type="entry name" value="Rcmb_RecR_C4-type_Zn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034137">
        <property type="entry name" value="TOPRIM_RecR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30446">
        <property type="entry name" value="PTHR30446"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02132">
        <property type="entry name" value="RecR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13662">
        <property type="entry name" value="Toprim_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111304">
        <property type="entry name" value="SSF111304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00615">
        <property type="entry name" value="recR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5 7" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6 7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Toprim" evidence="8">
        <location>
            <begin position="71"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="7">
        <location>
            <begin position="47"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="190" mass="20476" checksum="4DB0D85EBF1DFEB8" modified="2010-01-19" version="1">MEALRCLPGVGPKSAQRMAFSLLQRNRQGGLQLAEALNHAMTEIGHCRDCRTFTEDDICAICDNPRRKENGIVCVVESPADIVAVEATGQFSGRYFVLMGHLSPLDGIGPSDIGLDTLEFRLQNEAISELILATNPTVEGEATAHYIAELCQEYGVPASRIAHGVPVGGELELVDGTTLSHSLAGRQKLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ21</accession>
    <name>D0YZ21_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Probable membrane transporter protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_002534</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300274.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002534"/>
    <dbReference type="EnsemblBacteria" id="EEZ41502">
        <property type="protein sequence ID" value="EEZ41502"/>
        <property type="gene ID" value="VDA_002534"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0730">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002781">
        <property type="entry name" value="TM_pro_TauE-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01925">
        <property type="entry name" value="TauE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="103"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="163"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="196"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="235"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="257" mass="27459" checksum="2D2559D80F7323D9" modified="2010-01-19" version="1">MIENIEPLTLAILGGVALVAGFIDAVAGGGGMLTVPALLSLGLPPHIALGTNKLAATFASSTAAWTYYRKLLFSPSFWKKSFIATFIGAVIGTLVVNQISTMWLEKALPLIILAAAIYTIWHPHPKTAQQSLPQVSASLYRKQWLQGSSLGFYDGLAGPGTGAFWTVSSMALYRLDILLASGLAKAMNFTSNMTSLVTFAILGHINFALGLTMGLCLMVGAYIGAHSAIRFGAKFIRPIFITVVMILAIKLAYQAWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ31</accession>
    <name>D0YZ31_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Beta/gamma crystallin 'Greek key' domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_002544</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the beta/gamma-crystallin family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41512">
        <property type="protein sequence ID" value="EEZ41512"/>
        <property type="gene ID" value="VDA_002544"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3342">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001064">
        <property type="entry name" value="Beta/gamma_crystallin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011024">
        <property type="entry name" value="G_crystallin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00030">
        <property type="entry name" value="Crystall"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00247">
        <property type="entry name" value="XTALbg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49695">
        <property type="entry name" value="SSF49695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50915">
        <property type="entry name" value="CRYSTALLIN_BETA_GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019256" description="Beta/gamma crystallin 'Greek key' domain-containing protein" evidence="3">
        <location>
            <begin position="22"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="Beta/gamma crystallin 'Greek key'" evidence="4">
        <location>
            <begin position="149"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="188" mass="20868" checksum="ED8690C7F1A1EE2E" modified="2010-01-19" version="1">MKRIFSWLSAAAFLFSSSSFAAINFNQNIIVSGSNNGSVSRSVSVCVLNPFTKIFAEAGITEAQARRNVSLACQRDQGSNSIFCEESKARCHQSQLWSGDLTSGNSGELIIYNMRNQAGRTVTVTDNIADLSNVQFDNTLESFEIPVGWTVRFYEDKNFSGDYYTRTAGKYNADGFMNKISSIQIMQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZB4</accession>
    <name>D0YZB4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002627</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300532.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002627"/>
    <dbReference type="EnsemblBacteria" id="EEZ41595">
        <property type="protein sequence ID" value="EEZ41595"/>
        <property type="gene ID" value="VDA_002627"/>
    </dbReference>
    <dbReference type="GeneID" id="57341118"/>
    <dbReference type="eggNOG" id="ENOG5033HC1">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1563071at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019263" evidence="1">
        <location>
            <begin position="22"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="178" mass="18667" checksum="BC30E82366B0766C" modified="2010-01-19" version="1">MKLKIASLALCAAMAAPAAMADTPIQLSVPGVNLPAGNVTGVRLNALYGHTSSVTGVNFSFLGLSDIDTFKGLNFGLAFGINRTRSMMTGVEFGLANWNDGNAKGVDFGLANYTAGNFTGAQFGTFNYAGTLNGLQFGFVNATDHINQGVQIGLINYDKSGTFVSKNLPVFPIINARF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZF3</accession>
    <name>D0YZF3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative outer membrane protein OmpK</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002666</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the nucleoside-specific channel-forming outer membrane porin (Tsx) (TC 1.B.10) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300650.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002666"/>
    <dbReference type="EnsemblBacteria" id="EEZ41634">
        <property type="protein sequence ID" value="EEZ41634"/>
        <property type="gene ID" value="VDA_002666"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3248">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="914393at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.230.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018013">
        <property type="entry name" value="Channel_Tsx-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036777">
        <property type="entry name" value="Channel_Tsx-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03502">
        <property type="entry name" value="Channel_Tsx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111364">
        <property type="entry name" value="SSF111364"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019901" evidence="2">
        <location>
            <begin position="23"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="267" mass="30003" checksum="A7A4510C87E8DB79" modified="2010-01-19" version="1">MRKSLVALSVLAATALPSVVNAADYSDDIHKNDYKWMNFNLMYALGELPRAKDAHSGHDYLEMEFGGRSGVIDLYGYVDVFNLTNSDSQDKSGSDDKMFMKFAPRFSLDGMTGKDLSFGPVQELYIATLMNWGGNNGGVNNYFIGLGSDVNVPWLGKIGLNLYGLYDANIKDWNGYQISTNWFKPFYTFANGTFLSYQGYIDYQFGMKDKYSSASNGGAMFNGLYWHSERFAVGYGLKAYYNVYGIKDTDAFESTGVAHYFDITYKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZI4</accession>
    <name>D0YZI4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7 9">GTPase Der</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">GTP-binding protein EngA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">der</name>
        <name evidence="12" type="ORF">VDA_002697</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 9">GTPase that plays an essential role in the late steps of ribosome biogenesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Associates with the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8 9">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300728.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002697"/>
    <dbReference type="EnsemblBacteria" id="EEZ41665">
        <property type="protein sequence ID" value="EEZ41665"/>
        <property type="gene ID" value="VDA_002697"/>
    </dbReference>
    <dbReference type="GeneID" id="57341032"/>
    <dbReference type="eggNOG" id="COG1160">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="263682at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00195">
        <property type="entry name" value="GTPase_Der"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031166">
        <property type="entry name" value="G_ENGA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016484">
        <property type="entry name" value="GTP-bd_EngA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032859">
        <property type="entry name" value="KH_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14714">
        <property type="entry name" value="KH_dom-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006485">
        <property type="entry name" value="GTP-binding_EngA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03594">
        <property type="entry name" value="GTPase_EngA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51712">
        <property type="entry name" value="G_ENGA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5 7 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 7" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="EngA-type G" evidence="11">
        <location>
            <begin position="3"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="domain" description="EngA-type G" evidence="11">
        <location>
            <begin position="211"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="476"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="9"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="56"/>
            <end position="60"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="118"/>
            <end position="121"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="217"/>
            <end position="224"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="264"/>
            <end position="268"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="329"/>
            <end position="332"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ41665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="499" mass="56030" checksum="514FFC72B73441C5" modified="2010-01-19" version="1">MIPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGRAEINEHEFIVIDTGGIDGTEEGVETKMAEQSLMAIEEADVVLFLVDGRAGLTAADEAIAKHLRSRNKPTFLVVNKIDGIDADSACADFWKLGADEMHQIAASQNRGVTALMERALEPFFENISGSDEELESDEISIEDLNSVAEIENANLSEQDAEAAYKRLQEQPIKLAIIGRPNVGKSTLTNRILGEERVVVYDMPGTTRDSIYIPMERDGQEYVLIDTAGIRRRKNMHEAVEKFSVIQTLKAVEDANVVLLIIDARENISDQDLSLLGFALNAGRSLVIAVNKWDGLDNDVKERVKTELDRRLGFVDFARIHFISALHGTGVGHLYESVVEAYQSATKRISTSMLTRIMQMAQDDHQPPMIRGRRVKLKYAHAGGYNPPIIVVHGNLVNELPGSYKRYLMNYYRKSLEMMGTPIRIQFQNSENPFETKKEKLTISQQRQRKRLASMIKDRNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZL9</accession>
    <name>D0YZL9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Phosphate transport system permease protein PstC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_002732</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300849.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002732"/>
    <dbReference type="EnsemblBacteria" id="EEZ41700">
        <property type="protein sequence ID" value="EEZ41700"/>
        <property type="gene ID" value="VDA_002732"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4590">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1325025at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="455"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="490"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="519"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="553"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="602"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="650"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="718"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="449"/>
            <end position="737"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="751" mass="83411" checksum="988C368276422EB2" modified="2010-01-19" version="1">MANADSLFASDRLRRIKDSWARVGVTAGGISVLITLVLIFFYLLYVIGPIFSSVTVKPSQQFSLPLQGQTSALGTDDNNQLAYRFSFEGTVDFVRLFQAEKTLTEQDRAASQQSHLVTTKSVITNPTAFAASLPRDQLFVYGNEQGQAMVVKPDFVTHFADGHKTVVPELLYPAGKQALQLAPVDDPLVKLAISGREGDAALVGKTQSGQFYAMVFWTHGLDSSQHQWQYNRYPIIGLPANVTDFDVTPDGKTLYALSGKELYVVKLTKQQAMIRQVLSVSDDKTIPVGMYLLSGAQSLLLVNSDNTVNQWFEVVKDGKRTLVYAREFEFSASPIYKLIPEYFRKGFYAIQQDGTVSAYFTSEHNIIYQQKLFTSLPDFVAISPRANLLLTLNGEQWKSYSVDNLHPEIGLSSLWQKVWYEGYSEPDYVWQSTSASNEFEPKLSLVPIVFGTFKAAIYALFFAIPLALGGAIYTAYFMSSKMRRVVKPTIELMEALPTVILGFLAGIWLAPIVEKHLPGIVMILVLFPLTMLLVGLLWSILPGRWRHKIPNGMHIALLMPVIALLTYGCFAISPWIEQWLFHGDVRSYVTNELGIGYDQRNALVVGIAMGFAVIPTIFSIAEDAIFSVPKHLTNGSLALGATHWQTLTKVVLLTASPGIFSAVMMGLGRAVGETMIVLMATGNTPVMDWNILQGMRTLAATIAIEMPESEVGSSHYRVLFLAAFVLFVATFVFNTIAELVRQRLREKYRSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZP9</accession>
    <name>D0YZP9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha-D-GlcNAc alpha-1,2-L-rhamnosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002762</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300932.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002762"/>
    <dbReference type="EnsemblBacteria" id="EEZ41730">
        <property type="protein sequence ID" value="EEZ41730"/>
        <property type="gene ID" value="VDA_002762"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="694191at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="18"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="197"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="369" mass="41366" checksum="FF3E94268B9EBBC5" modified="2010-01-19" version="1">MNKSILVLGTRGIPNVQGGVESHCQSLYPLLVEKYNLDITVTARKPYVPYSESEYLGVKLKALPSVTNKSLEAPLHSLLAALYAIKEKADIVHIHAIGPGLVTPLLRLFGKKVVFTHHSQNYDHQKWGKLAKFVLRLGERCAVKYASEVIVISDFMQNLMEEKYGRKDTHLIFNGVHKPQLPEQHKINEYLSKFDLESRDYVVAVGRFSQEKGLDVLLDAYKKSGINKKLVLVGDCDHPTEYSDDPKKVAKETSGVVLTGFLSGEELHSIFSQADTFVLPSFSEGLPIALLEAMSFSLPVIVSDIPANKAVHLPNDRYFSCGNSDDLAKKLIESVGQPLISYDDYLQKYDWDLIAEQTYNVFQQAEHDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZU2</accession>
    <name>D0YZU2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002805</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301059.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002805"/>
    <dbReference type="EnsemblBacteria" id="EEZ41773">
        <property type="protein sequence ID" value="EEZ41773"/>
        <property type="gene ID" value="VDA_002805"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502Z80T">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="608311at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035438">
        <property type="term" value="F:cyclic-di-GMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009875">
        <property type="entry name" value="PilZ_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07238">
        <property type="entry name" value="PilZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PilZ" evidence="1">
        <location>
            <begin position="148"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="PilZ" evidence="1">
        <location>
            <begin position="471"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="784" mass="90619" checksum="34912EAFBAF62519" modified="2010-01-19" version="1">MQPVHDKGLLEQLVSLYHDGDFEPMFEMLTQDFSGPQKLQLKIELRQLMMPINKEIDLRGRVKGECRPYYLNERQHWLDDVALNIYHQRIQHYGGVLCYGLYQEIIHSRNSFRVLHKQQTETKPPQEPTQLLDPFAVNMIRFGHYLSREEHRVQISTQVTLVTDKQQTIHGNSYDLSFSGAKIKVPAAFHYQLGEVIALTFPILAEKLNDDRLNQSMYYRVLAIDDIAENQSSKWLRLTTTQDNLALKEAILKIKQVAAHSRDDHQDKFIRARTKGYEHCYLKHSTGLPLFFSQQQLSYALLTEHNRHLWHYWHDERNLPNINHLLNPQRMAMLTKHGLSHSRTLIYSFCHQHEGKSYFYSACLPEMSLEQRRLFWHLGAARDSWRVWQLTLSPLQGEDLAQLNELAPDQTQEYQNFTHIALLQDLTDTHAQQDYRLTLKPNASAKILQPFRHQRDPICQASAILFDPRPQRSEERFTYQTELTISHETGSFSGCTVDFSTKGLNIQLASPLVAKRDDEIAISFPQLQQKNKQLPLSDLRYRIVRINAEGTNLQAQLLDIVCNIKGESCLKNIVKHNAKHLAVCEEDRPQHVLLQAMHQLLLTRLDSVPYFVEKLEHKLTVTSIGCNIPLPSLAKLFQQFSHTQQPNGFSLAPIFKGRVQTMLAKTLRPVAITKPYSHELYLHLVHQQGKTQCVASWLLQEFESTQARITFIEHARSHGEIKVLRITAAPIFDSMTLLTQQKLSELARLTLHRARGLENEFSALVGCGEIFDITDEVLVRLAIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZV6</accession>
    <name>D0YZV6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ABC transporter transmembrane region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">VDA_002819</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301099.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002819"/>
    <dbReference type="EnsemblBacteria" id="EEZ41787">
        <property type="protein sequence ID" value="EEZ41787"/>
        <property type="gene ID" value="VDA_002819"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2274">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="643917at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017750">
        <property type="entry name" value="ATPase_T1SS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005074">
        <property type="entry name" value="Peptidase_C39"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03412">
        <property type="entry name" value="Peptidase_C39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03375">
        <property type="entry name" value="type_I_sec_LssB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50990">
        <property type="entry name" value="PEPTIDASE_C39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="178"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="212"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="288"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="314"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="397"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase C39" evidence="10">
        <location>
            <begin position="20"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="178"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="490"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="524"/>
            <end position="531"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ41787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="725" mass="80003" checksum="44075C25EBF18EDA" modified="2010-01-19" version="1">MVFVVEQQKKQEQWTIPASEKTTEDPLLDCLVLLSEHYGNPCSGEALLVGLPLNNAQLTPELFSQAASRIGLVAKLLRKPLDTLSPLVLPCILLLNNKKACILREIIPNQDKVIIQLPENGGESEIAISELNNIYTGYAFLVKQQYRGDKSIDVNFIEQKGHWLWSLVKDASPIYRDALLASILINIFVLVSPLFMMNVYDKIVPNLAFESLWVLASGVALVFTFDFILRHMRSYLIDLAGKKIDIIVSSQLFAKVLGIPLAKKGLSVGATAKQIGEFDSIRDMLTSVTLTTLVDLPFAALFLVIIYLVAGDLALIPLCAGILIIGYSLWVQPKLKFAVTEANKYSTIKHAHLIESLTAAEAIKSNVAEGIMQRSWQQMNAHTADWQLKLKKLSNSVAFFATYITQLTTVGVVILGVYRLSTLDISMGGIIAAVMLSGRVVSPMAQLANLLTRSNQTANALTQLDLLMEQEDEFTGKAHLISRHRLKGAIQAENLQFIYPQQKRSTLYPCNFNIKPGEKIAILGKNGSGKTSLAKLLAGLYQPSDGQLRFDGINESQIHPADLRKNIGYMPQDITLIHGTIRDNIMFGHRQVTEHQLLRAVQLSGVAQFCTEDSEGLDKQVGEGGLSLSRGQRQSVALARAILVDPPILLMDEPTASMDAITEQQFIQSIQRILPNKTLVMITHKMSLLTLVDRVMVLDKGQIILDGEKAPVLEKLRRGLVGGEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZW4</accession>
    <name>D0YZW4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ubiquinone biosynthesis protein UbiV</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ubiV</name>
        <name evidence="2" type="ORF">VDA_002827</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiU, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Forms an heterodimer with UbiU.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase U32 family. UbiV subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301124.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002827"/>
    <dbReference type="EnsemblBacteria" id="EEZ41795">
        <property type="protein sequence ID" value="EEZ41795"/>
        <property type="gene ID" value="VDA_002827"/>
    </dbReference>
    <dbReference type="GeneID" id="57340891"/>
    <dbReference type="eggNOG" id="COG0826">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1725274at2"/>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02233">
        <property type="entry name" value="UbiV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001539">
        <property type="entry name" value="Peptidase_U32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043693">
        <property type="entry name" value="UbiV"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01136">
        <property type="entry name" value="Peptidase_U32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="292" mass="32953" checksum="4BDE04B4306FD350" modified="2010-01-19" version="1">MKYALGPILYFWPKTDVEAFYQQAQSANVDIIYLGETVCSKRREMKAADWFEIAKSLADNGKQVVLSTMALLEAPSEVNVMKKYIDNGDFIIEANDVSAIQLAHEHRVPFVVGPAVNCYNAQTLNLFLKKGMTRWCMPVELSRDWLQNTLAECEQLGIRGQFETEVFSYGYLPLAYSARCFTARAEDRAKDDCETCCIKYPTGITVKSQESQKVFTLNGIQTQSGYCYNLINDLQGMQELVDVVRLSPLGVDTLGLVDEFRQNEQGQNRHTLADGHQCNGYWHNLAGLNIQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZZ5</accession>
    <name>D0YZZ5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase</fullName>
            <ecNumber evidence="2">2.5.1.145</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">lgt</name>
        <name evidence="3" type="ORF">VDA_002858</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + L-cysteinyl-[prolipoprotein] = H(+) + S-1,2-diacyl-sn-glyceryl-L-cysteinyl-[prolipoprotein] + sn-glycerol 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:56712"/>
            <dbReference type="Rhea" id="RHEA-COMP:14679"/>
            <dbReference type="Rhea" id="RHEA-COMP:14680"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57685"/>
            <dbReference type="ChEBI" id="CHEBI:64716"/>
            <dbReference type="ChEBI" id="CHEBI:140658"/>
            <dbReference type="EC" id="2.5.1.145"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; lipoprotein biosynthesis (diacylglyceryl transfer).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the Lgt family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.145" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301219.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002858"/>
    <dbReference type="EnsemblBacteria" id="EEZ41826">
        <property type="protein sequence ID" value="EEZ41826"/>
        <property type="gene ID" value="VDA_002858"/>
    </dbReference>
    <dbReference type="GeneID" id="57340854"/>
    <dbReference type="eggNOG" id="COG0682">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="435911at2"/>
    <dbReference type="UniPathway" id="UPA00664"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008961">
        <property type="term" value="F:phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042158">
        <property type="term" value="P:lipoprotein biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01147">
        <property type="entry name" value="Lgt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001640">
        <property type="entry name" value="Lgt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30589">
        <property type="entry name" value="PTHR30589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01790">
        <property type="entry name" value="LGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00544">
        <property type="entry name" value="lgt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01311">
        <property type="entry name" value="LGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="90"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="177"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="202"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="239"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)</name>
            <dbReference type="ChEBI" id="CHEBI:64716"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="267" mass="29896" checksum="9AB013DEFFD5F6E8" modified="2010-01-19" version="1">MQGYLTFPQIDPVLVQIGPLAIRWYGLMYLIGFAFAMWLANRRADQPGSGWTKDQVSDLLFAGFLGVVIGGRIGYVLFYNFDLFLANPLYLFKVWTGGMSFHGGLLGVITAMFWYGHKNGRTFFSIADFIAPLVPFGLGMGRLGNFINGELWGRVTDVPWAMIFPTGGPLPRHPSQLYEFLLEGVVLFIILNLFIRKPRPTGAVSGLFLLCYGSFRFFVEFFRQPDAQLGFFDGWLTMGQILSTPMILLGAAILIWAYKKKPESSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z042</accession>
    <name>D0Z042_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">(GlcNAc)2 ABC transporter: substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002905</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301313.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002905"/>
    <dbReference type="EnsemblBacteria" id="EEZ41873">
        <property type="protein sequence ID" value="EEZ41873"/>
        <property type="gene ID" value="VDA_002905"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0747">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="162819at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030678">
        <property type="entry name" value="Peptide/Ni-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002741">
        <property type="entry name" value="MppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019275" evidence="1">
        <location>
            <begin position="29"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="domain" description="SBP_bac_5" evidence="2">
        <location>
            <begin position="77"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="558" mass="63156" checksum="0B339984283DA8CB" modified="2010-01-19" version="1">MLANIKKTKLALAVVAAATAFTAPTVSAAEKSQLTIVPDFYPTMVRNFNPYLATNLRTTTDFIYEPLVIFNQMKGNEPVMRLAKNYFMSDDLMKVTFEIRDGVKWSDGKPFTADDVVYSFELLKNKPELDQRGINKWVKGVKKDGNKVIFDLTEANSNVPYEISFVPVVAKHVWSKVKDPTSFTNENPVGTGPFTVIETFTPQLYVQCRNPNYWDNANLEVDCLRVPQIANNDQLLGKIINSELDWTSSFVPDIDSTYAAANPNHKYWYPASGTQSFMLNFKSPKDGNKEAINNVDFRRAFSMAIDRQTIIDIAFYGNGTPNDYASGLGKVFEFWSDKPTHDKYKAFNTYSVKGSKDLLAKAGFKDLDGDGFVESPTGKKIELEVQSPNGWTDFNNTVQLAVEQLQEVGINAKARTPDFAVYNEAMLKGTYDVAYTNYFHGADPHLYWDSAYNSRLQQGEGMPRFAMHYFKNAELDSLLNSFYKTADKQEQIQIAHKIQKIIAENQVTVPVMSGADMFQYNETRFTGWWNEKNPKGRPMVWAGVPERLLQVLDLKPKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z073</accession>
    <name>D0Z073_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA</fullName>
            <shortName evidence="2">3',5'-cyclic AMP phosphodiesterase</shortName>
            <shortName evidence="2">cAMP phosphodiesterase</shortName>
            <ecNumber evidence="2">3.1.4.53</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">cpdA</name>
        <name evidence="4" type="ORF">VDA_002936</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>3',5'-cyclic AMP + H2O = AMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:25277"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58165"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="3.1.4.53"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="2">Binds 2 Fe(2+) ions per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the cyclic nucleotide phosphodiesterase class-III family.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.53" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301386.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002936"/>
    <dbReference type="EnsemblBacteria" id="EEZ41904">
        <property type="protein sequence ID" value="EEZ41904"/>
        <property type="gene ID" value="VDA_002936"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1409">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1242748at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004115">
        <property type="term" value="F:3',5'-cyclic-AMP phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07402">
        <property type="entry name" value="MPP_GpdQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00905">
        <property type="entry name" value="cAMP_phosphodiest_CpdA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046379">
        <property type="entry name" value="cAMP_phosphodiest_CpdA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026575">
        <property type="entry name" value="GpdQ/CpdA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0114">cAMP</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="3">
        <location>
            <begin position="16"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="21"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="23"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="93"/>
            <end position="94"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00025742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="275" mass="30681" checksum="EB13A351DF3A3869" modified="2010-01-19" version="1">MLTYSLPPRQSDSVVLLQITDTHLFANDAGSLLGVATKDSFHAVLAAIDHQARPFDAIIATGDISQDHSTESYQHFAQGIARWQQPCFWLPGNHDYQPSMKAVLPSPQIKPCEQVLLGEHWQMILLDSQVPGVPHGELRAEQLEMLDRALAAHSERHALVLLHHHPLAAGSAWLDQHQLHNADDFWQVLARYPAKVKSVLCGHIHQELDCMRQGVRVLATPSTCIQFLPDSDDFALDSKAPGWRYLELTPQGDVHTQIHRLANDQFAPDLNSAGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0G6</accession>
    <name>D0Z0G6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 10">Adenylosuccinate synthetase</fullName>
            <shortName evidence="8">AMPSase</shortName>
            <shortName evidence="8">AdSS</shortName>
            <ecNumber evidence="8 10">6.3.4.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">IMP--aspartate ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">purA</name>
        <name evidence="11" type="ORF">VDA_003030</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 10">
            <text>GTP + IMP + L-aspartate = GDP + 2 H(+) + N(6)-(1,2-dicarboxyethyl)-AMP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:15753"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57567"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="6.3.4.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="8">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8 10">Purine metabolism; AMP biosynthesis via de novo pathway; AMP from IMP: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1 8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8 10">Belongs to the adenylosuccinate synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.4" evidence="8 10"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301639.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003030"/>
    <dbReference type="EnsemblBacteria" id="EEZ41997">
        <property type="protein sequence ID" value="EEZ41997"/>
        <property type="gene ID" value="VDA_003030"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0104">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="232152at2"/>
    <dbReference type="UniPathway" id="UPA00075">
        <property type="reaction ID" value="UER00335"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004019">
        <property type="term" value="F:adenylosuccinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044208">
        <property type="term" value="P:'de novo' AMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd03108">
        <property type="entry name" value="AdSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00011">
        <property type="entry name" value="Adenylosucc_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018220">
        <property type="entry name" value="Adenylosuccin_syn_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033128">
        <property type="entry name" value="Adenylosuccin_syn_Lys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042109">
        <property type="entry name" value="Adenylosuccinate_synth_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042110">
        <property type="entry name" value="Adenylosuccinate_synth_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042111">
        <property type="entry name" value="Adenylosuccinate_synth_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001114">
        <property type="entry name" value="Adenylosuccinate_synthetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11846">
        <property type="entry name" value="PTHR11846"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00709">
        <property type="entry name" value="Adenylsucc_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00788">
        <property type="entry name" value="Adenylsucc_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00184">
        <property type="entry name" value="purA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01266">
        <property type="entry name" value="ADENYLOSUCCIN_SYN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00513">
        <property type="entry name" value="ADENYLOSUCCIN_SYN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 8 10" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 8 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 8 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 8 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 8 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 8 10" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="IMP binding" evidence="8">
        <location>
            <begin position="14"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="region of interest" description="IMP binding" evidence="8">
        <location>
            <begin position="39"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="306"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="14"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="42"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="141"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="13"/>
            <end position="19"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="41"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="225"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="240"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="310"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="312"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="338"/>
            <end position="340"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="421"/>
            <end position="423"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ41997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="438" mass="47930" checksum="43B3418FCA39D0F6" modified="2010-01-19" version="1">MANNVVVLGTQWGDEGKGKIVDLLTEDAKYVVRYQGGHNAGHTLVIDGEKTVLHLIPSGILRDNVKCIIGNGVVLSPDALMKEMGPLEERGIPVRERLFLSEACPLILPYHIALDQAREIARGKKAIGTTGRGIGPAYEDKVARRGLRVGDLFNKEAFAEKLKEVMAYHNFQLEHYYNAEPVSYEEVLEGVMAQADILTSMVIDVTKELDDARLRGDKIMFEGAQGTLLDIDHGTYPYVTSSNTTAGGVAAGSGFGPRHLGYILGIAKAYCTRVGAGPFPTELYDGLEKQDPIGKHLGTVGHEFGATTGRLRRTGWFDAVAMRRAVQINSISGFCLTKLDVLDGLEELKICTGYKTKTGEILEVSPMAADEYEDLELIYETMPGWSEKTFGVKTLEELPQTALDYIARIEELTGVPVDIISTGPDRNETIIKVHPYGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0H3</accession>
    <name>D0Z0H3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N-acetylmuramoyl-L-alanine amidase</fullName>
            <ecNumber evidence="2">3.5.1.28</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_003037</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides.</text>
            <dbReference type="EC" id="3.5.1.28"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="3.5.1.28" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301660.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003037"/>
    <dbReference type="EnsemblBacteria" id="EEZ42004">
        <property type="protein sequence ID" value="EEZ42004"/>
        <property type="gene ID" value="VDA_003037"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0860">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1388">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1184688at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008745">
        <property type="term" value="F:N-acetylmuramoyl-L-alanine amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009253">
        <property type="term" value="P:peptidoglycan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="CDD" id="cd02696">
        <property type="entry name" value="MurNAc-LAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021731">
        <property type="entry name" value="AMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002508">
        <property type="entry name" value="MurNAc-LAA_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01520">
        <property type="entry name" value="Amidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11741">
        <property type="entry name" value="AMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00646">
        <property type="entry name" value="Ami_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="SSF54106"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019939" description="N-acetylmuramoyl-L-alanine amidase" evidence="4">
        <location>
            <begin position="24"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="5">
        <location>
            <begin position="405"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="5">
        <location>
            <begin position="480"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="5">
        <location>
            <begin position="531"/>
            <end position="574"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ42004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="577" mass="62804" checksum="BF67D9BD2E5DFCFF" modified="2010-01-19" version="1">MALRSYLNLLIVGASLVSSSVWANELKGVRVWPAPDETRVVLDMQDKPVYSTFTLTKPDRLVVDLKTTSKDTKLPVVVKNSEILSQIRSSNAPKKGDFRLVFEIKDDVKPNIFALAPTPGGRYGHRLVLDLPHPGGESNLVVDKSKSTPATSQATAHMPKSMGKIVIAIDAGHGGEDPGSIGPHRKYEKNVTLAIAKKLAAKLNSTSGMEAVMTRRGDYYVGLSKRSEIARKNKALLLVSIHADAFTNPRPRGASVWVLNNRRANTEIGRWLEQSEKQSELLGGGDVLSGNSQDKYLSRAVLDLQFSHSQKEGYDVAESVLHQLRRVTRLHKSQPQHASLAVLKSPDIPSLLVETGFISNPTEERLLTSPAHQAKIADAVYRGIVDYFKANPPQGTMFASRGSTVKHKVTSGQTLSGIANRYGVSMATIRSANNLKSNSVNIGQVLVIPRGGNVVSTPSQKSVATKTAAISSSSTSTKVIYHTVKRGEYLGQLAEKYGTTMSRIRSLNKLKSDNVMLGQKLKIEVKAPKQITHKVQRGEFLSKIASKYGVSIASIRNANKLRSDKLAVGQTLIIPRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0M2</accession>
    <name>D0Z0M2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Branched-chain amino acid transport system carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_003086</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the transport system for branched-chain amino acids.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell inner membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the branched chain amino acid transporter family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301818.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ42053">
        <property type="protein sequence ID" value="EEZ42053"/>
        <property type="gene ID" value="VDA_003086"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1114">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1533843at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015658">
        <property type="term" value="F:branched-chain amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004685">
        <property type="entry name" value="Brnchd-chn_aa_trnsp_Livcs"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30588">
        <property type="entry name" value="PTHR30588"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05525">
        <property type="entry name" value="Branch_AA_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00796">
        <property type="entry name" value="livcs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="38"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="75"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="116"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="146"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="187"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="220"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="270"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="313"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="335"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="365"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="405"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ42053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="440" mass="46267" checksum="972AC4EE3717965E" modified="2010-01-19" version="1">MLSARNIAALGFMTFAMYLGAGNLIFPPFLGYQAGDNFMSGMMGFLLTGVGLPALALVMVALVKGSDNLTAALPKPLATAFWVMVFIVIGPAFVIPRAITVAYQFSFAPFLGDNSALVPFSIAFCLIVVLFSLFPGKLVDTVGKWLTPALLAILAVMAVFAFLFPMGKVEMATGPYVNGAFAEGLTQGYMTMDALGSIGFGWVIFRAIKSMGVDCPRATAKYTLMAAAMYAAAMAAVYLSLAYIGTNSANLGVEFTNGGEILTAFTNLHFGAFGTMLLGVVMVLACLTTAIGVTTAGSEFYSRTFSKVTYSKSVWVTMILAGMIANVGLEQLLAITLPAVVALHPIAIALLLIAPLRKQLSSTMVLVAVATAAGFGIVDATHILGAMPEAVTAWCEHNLPLYHYYASWVVPTVVIIGLGWGVSAVNASRTAPEQVVCDNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0N4</accession>
    <name>D0Z0N4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein translocase subunit SecE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">secE</name>
        <name evidence="8" type="ORF">VDA_003098</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the SecE/SEC61-gamma family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301853.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003098"/>
    <dbReference type="EnsemblBacteria" id="EEZ42065">
        <property type="protein sequence ID" value="EEZ42065"/>
        <property type="gene ID" value="VDA_003098"/>
    </dbReference>
    <dbReference type="GeneID" id="57340423"/>
    <dbReference type="eggNOG" id="COG0690">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1974284at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043952">
        <property type="term" value="P:protein transport by the Sec complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00422">
        <property type="entry name" value="SecE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005807">
        <property type="entry name" value="SecE_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038379">
        <property type="entry name" value="SecE_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001901">
        <property type="entry name" value="Translocase_SecE/Sec61-g"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33910">
        <property type="entry name" value="PTHR33910"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00584">
        <property type="entry name" value="SecE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01650">
        <property type="entry name" value="SECETRNLCASE"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00964">
        <property type="entry name" value="secE_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01067">
        <property type="entry name" value="SECE_SEC61G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0811">Translocation</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="50"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="95"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ42065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="127" mass="13637" checksum="FF97037AF5501BC0" modified="2010-01-19" version="1">MNANAENENQESQSKMDGLKWLVVFALLAAAVVGNYLYSDVSVVLRVSGIVALVAIAGITAAFTAKGKAAITFAREARMEVRKVVWPTRQEATQTTFIVLAVTVVMALALWGIDGIMVRLVRLVTGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0V7</accession>
    <name>D0Z0V7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ferritin</fullName>
            <ecNumber evidence="1">1.16.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_003171</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Iron-storage protein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>4 Fe(2+) + 6 H2O + O2 = 12 H(+) + 4 iron(III) oxide-hydroxide</text>
            <dbReference type="Rhea" id="RHEA:11972"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:78619"/>
            <dbReference type="EC" id="1.16.3.2"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ferritin family. Prokaryotic subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.16.3.2" evidence="1"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302067.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003171"/>
    <dbReference type="EnsemblBacteria" id="EEZ42138">
        <property type="protein sequence ID" value="EEZ42138"/>
        <property type="gene ID" value="VDA_003171"/>
    </dbReference>
    <dbReference type="GeneID" id="57340595"/>
    <dbReference type="eggNOG" id="COG1528">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1890523at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:cellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006826">
        <property type="term" value="P:iron ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01055">
        <property type="entry name" value="Nonheme_Ferritin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001519">
        <property type="entry name" value="Ferritin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009040">
        <property type="entry name" value="Ferritin-like_diiron"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008331">
        <property type="entry name" value="Ferritin_DPS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041719">
        <property type="entry name" value="Ferritin_prok"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11431">
        <property type="entry name" value="PTHR11431"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00210">
        <property type="entry name" value="Ferritin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50905">
        <property type="entry name" value="FERRITIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0409">Iron storage</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ferritin-like diiron" evidence="2">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU361145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ42138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="175" mass="19859" checksum="8643E14471D51E6E" modified="2010-01-19" version="1">MLAQAMVEKLNEQINLEFFSSNLYLQMSAWCEDKGFEGAAAFLRSHAVEEMEHMQRLFTYVSETGALPILGTIAAPKHEFASLGDVFRETYEHEQLITEKINKLAHVAFTTQDYSTFNFLQWYVAEQHEEEKLFKGILDKIELVGEDGKALFFIDKDLAEMAKSGSTSVMDTQAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0X3</accession>
    <name>D0Z0X3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted arginine uptake transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_003187</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302108.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003187"/>
    <dbReference type="EnsemblBacteria" id="EEZ42154">
        <property type="protein sequence ID" value="EEZ42154"/>
        <property type="gene ID" value="VDA_003187"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3314">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="819609at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011642">
        <property type="entry name" value="Gate_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07670">
        <property type="entry name" value="Gate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="215"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="243"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="322"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="364"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="397"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="432"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="domain" description="Gate" evidence="2">
        <location>
            <begin position="141"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ42154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="455" mass="49024" checksum="5793C31538D86F19" modified="2010-01-19" version="1">MQEHVAKPPAKSKSNWMMFLLPSLIGVFLFMAPISYDGNITIPIAVLAKTVQQLFEGSLVDIVTFVISFTAVMSIITKTIKPSFITRNAFLNGLFNPSTAWFIVQLLGGAFVLMTYFGFGPAMISDGATGGLVLNDLLPVLFSVFIFAGLLLPLLLNFGLLEFFGTLFTRIMRPVFGLPGRSSVNCIASWLGDGSVGVLLTSKQYEKGMYTQREAAIIGTTFSAVSITFSLVVITQVGLANMFAPFYLTVCLAGFVAAVVVPRLPPLSWKKDVYIDGTTEKEDFEAVPAGHNVVSYGLEQALNKAAEVKSLRAVALDGVKNAVDMVFGVLPIVMAIGTIALVVAENTPVFELLGQPFIPFLELLHVPEAAAASETIVVGFADMFLPSILASGIESEMTRFIIAAMSVTQLIYMSEIGALLVGSKVPVKIWELFVIFILRTLVTLPVIAGVAHLIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z143</accession>
    <name>D0Z143_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alcohol dehydrogenase</fullName>
            <ecNumber evidence="2">1.1.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003257</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.1" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302311.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003257"/>
    <dbReference type="EnsemblBacteria" id="EEZ42224">
        <property type="protein sequence ID" value="EEZ42224"/>
        <property type="gene ID" value="VDA_003257"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0604">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="884088at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004022">
        <property type="term" value="F:alcohol dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014188">
        <property type="entry name" value="Acrylyl-CoA_reductase_AcuI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43677:SF1">
        <property type="entry name" value="PTHR43677:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02823">
        <property type="entry name" value="oxido_YhdH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="14"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="326" mass="34864" checksum="9F716E1ACBDD802C" modified="2010-01-19" version="1">MFKALVLNQEDKKTLVSIEQLDESQLPEGDVLIDVDYSSLNYKDGLAITGKGRIVRQFPMVPGIDLVGTVSQSNDNRYQAGDKVVLTGWGVGEGHWGGMAEKARLKADWLVPMPQAFDGKQAMMIGTAGVTAMLCVQALVDAGVKPQDGEVLVTGASGGVGSVAVTLLSQLGYQVVAVTGRVAKNGELLKQLGASRVVERSEFAEPVRPLDKQLWAGAIDTVGSTMLAKVLSQVNYDGAVAICGLAGGFDLPTTVMPFILRNVKLLGVDSVMCPFEKRQQAWQRLGELLPASYFEQACREVTLEQVPECAEAITNGQITGRVVIKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z196</accession>
    <name>D0Z196_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycerol-3-phosphate regulon repressor DeoR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003310"/>
    <dbReference type="EnsemblBacteria" id="EEZ42277">
        <property type="protein sequence ID" value="EEZ42277"/>
        <property type="gene ID" value="VDA_003310"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1349">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014036">
        <property type="entry name" value="DeoR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00455">
        <property type="entry name" value="DeoRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DeoRC" evidence="1">
        <location>
            <begin position="3"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="181" mass="19983" checksum="5A7B73957EC2161A" modified="2010-01-19" version="1">MQLAEKDRIAQAMVAHIPDGATLFIDIGTTPEAVARALLNHNDLRIVTNNLNVAGTLMAKEDFRVILAGGEVRNRDGGIVGEATLDFVSQFRLDFGILGISGIELDGSLLDFDYHEVRVKQAIIENSRCVMLGVDHTKFGRNAMVNLGDISQIDMLFTDQEPPAELMQRLQECELTMEIIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1A7</accession>
    <name>D0Z1A7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SURF1-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003321</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the SURF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302488.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003321"/>
    <dbReference type="EnsemblBacteria" id="EEZ42288">
        <property type="protein sequence ID" value="EEZ42288"/>
        <property type="gene ID" value="VDA_003321"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1908280at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd06662">
        <property type="entry name" value="SURF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002994">
        <property type="entry name" value="Surf1/Shy1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02104">
        <property type="entry name" value="SURF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50895">
        <property type="entry name" value="SURF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="210"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="240" mass="28416" checksum="F411FFA1208138B1" modified="2010-01-19" version="1">MKRISFLLFTLLMVALCLRLSWWQVERAQEKSQRQVMLERRSEQTYHHIDSLPNDPRWYQLNVMGQFDQRHAILLDNQIHQGRVGYQVLLPFVSQQRLFLINLGWLAAPRYREQLPSIPHYYLPIRLTGLIDIPQSLLQLGEQVDELEELIQEPNSLQQQVLRVQNLNLEQLAQKLQKPLEPWILQLDPNHKLALQQHWQAVVIGPQKHYAYALQWGLIAVAILLLSLWWQRRVKHGQTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1B2</accession>
    <name>D0Z1B2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fe/S biogenesis protein NfuA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">nfuA</name>
        <name evidence="8" type="ORF">VDA_003326</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="5">Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the NfuA family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302497.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003326"/>
    <dbReference type="EnsemblBacteria" id="EEZ42293">
        <property type="protein sequence ID" value="EEZ42293"/>
        <property type="gene ID" value="VDA_003326"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0316">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0694">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051604">
        <property type="term" value="P:protein maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.300.12">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01637">
        <property type="entry name" value="Fe_S_biogen_NfuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017726">
        <property type="entry name" value="Fe/S_biogenesis_protein_NfuA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000361">
        <property type="entry name" value="FeS_biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034904">
        <property type="entry name" value="FSCA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035903">
        <property type="entry name" value="HesB-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001075">
        <property type="entry name" value="NIF_FeS_clus_asmbl_NifU_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01521">
        <property type="entry name" value="Fe-S_biosyn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01106">
        <property type="entry name" value="NifU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117916">
        <property type="entry name" value="SSF117916"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89360">
        <property type="entry name" value="SSF89360"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03341">
        <property type="entry name" value="YhgI_GntY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3 5" id="KW-0408">Iron</keyword>
    <keyword evidence="4 5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe-S_biosyn" evidence="7">
        <location>
            <begin position="2"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="NifU" evidence="6">
        <location>
            <begin position="111"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ42293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="192" mass="20812" checksum="3D945BA8B6E34FDE" modified="2010-01-19" version="1">MITISASAQEHFGKLLAQQPEGTNIRVFVVNPGTPNAECGVSYCPPEAVEANDTEIKFDLFSAFVDELSLPFLTDAQIDFVTDKMGSQLTLKAPNAKVRKVADDAPLMERVDYVIQTQVNPQLAGHGGHISLIEITEDGIAVIQFGGGCNGCSMVDVTLKEGIEKELLAQFEGELNAVRDVTEHARGDHSYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1C7</accession>
    <name>D0Z1C7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nucleoid occlusion factor SlmA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">slmA</name>
        <name evidence="7" type="ORF">VDA_003341</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer. Interacts with FtsZ.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
            <location evidence="4">Nucleoid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the nucleoid occlusion factor SlmA family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302526.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003341"/>
    <dbReference type="EnsemblBacteria" id="EEZ42308">
        <property type="protein sequence ID" value="EEZ42308"/>
        <property type="gene ID" value="VDA_003341"/>
    </dbReference>
    <dbReference type="GeneID" id="57340214"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043590">
        <property type="term" value="C:bacterial nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010974">
        <property type="term" value="P:negative regulation of division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01839">
        <property type="entry name" value="NO_factor_SlmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023769">
        <property type="entry name" value="NO_SlmA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 4" id="KW-0132">Cell division</keyword>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="6">
        <location>
            <begin position="7"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="5">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ42308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="196" mass="22728" checksum="D6C0787EDB1A67A3" modified="2010-01-19" version="1">MAGNKKNNRREEILQALAQMLESPQGSQRITTVKLAAQVGFSEAALYRHFPSKARMFEGLIEFIEDSITTRINRILDDEKDTLNRLRMVLQLILVFAERNPGLTRIMTGHALMFEQDRLQARINQLFERIETQLRQILRERKLREGKGFPVDESILAAQLLGQVEGSLNRFVRSNFKYKPTESFDDYWQLLSSQLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-08-12" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1L6</accession>
    <name>D0Z1L6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein SlyX homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">slyX</name>
        <name evidence="3" type="ORF">VDA_003430</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SlyX family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302697.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003430"/>
    <dbReference type="EnsemblBacteria" id="EEZ42397">
        <property type="protein sequence ID" value="EEZ42397"/>
        <property type="gene ID" value="VDA_003430"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2900">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2039245at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00715">
        <property type="entry name" value="SlyX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007236">
        <property type="entry name" value="SlyX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36508">
        <property type="entry name" value="PTHR36508"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04102">
        <property type="entry name" value="SlyX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="11"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ42397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="73" mass="8614" checksum="8E1A7CDDD0B197E7" modified="2010-01-19" version="1">MTEQQQLLARIDELEMKQAFQEQTIEELNQALTEQQFLIEKLMLQMKFMVGKVKGMEPSNMARESEETPPPHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1R6</accession>
    <name>D0Z1R6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 19">Methionine synthase</fullName>
            <ecNumber evidence="6 19">2.1.1.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="19">5-methyltetrahydrofolate--homocysteine methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="29" type="ORF">VDA_003480</name>
    </gene>
    <organism evidence="29 30">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="29 30" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="29 30">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="18 19">Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>(6S)-5-methyl-5,6,7,8-tetrahydrofolate + L-homocysteine = (6S)-5,6,7,8-tetrahydrofolate + L-methionine</text>
            <dbReference type="Rhea" id="RHEA:11172"/>
            <dbReference type="ChEBI" id="CHEBI:18608"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58199"/>
            <dbReference type="EC" id="2.1.1.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 19 22">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 19 21">
            <name>methylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:28115"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4 19">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-methionine from L-homocysteine (MetH route): step 1/1.</text>
    </comment>
    <comment type="domain">
        <text evidence="19">Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the vitamin-B12 dependent methionine synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.13" evidence="6 19"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303565.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003480"/>
    <dbReference type="EnsemblBacteria" id="EEZ42447">
        <property type="protein sequence ID" value="EEZ42447"/>
        <property type="gene ID" value="VDA_003480"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0646">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1410">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="118138at2"/>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00081"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008705">
        <property type="term" value="F:methionine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042558">
        <property type="term" value="P:pteridine-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02069">
        <property type="entry name" value="methionine_synthase_B12_BD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1240.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.196.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.330">
        <property type="match status" value="1"/>
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        <property type="entry name" value="Cbl-bd_cap"/>
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        <property type="entry name" value="Cobalamin-bd"/>
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        <property type="entry name" value="Cobalamin-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011005">
        <property type="entry name" value="Dihydropteroate_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003726">
        <property type="entry name" value="HCY_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036589">
        <property type="entry name" value="HCY_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033706">
        <property type="entry name" value="Met_synthase_B12-bd"/>
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    <dbReference type="InterPro" id="IPR011822">
        <property type="entry name" value="MetH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036594">
        <property type="entry name" value="Meth_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000489">
        <property type="entry name" value="Pterin-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004223">
        <property type="entry name" value="VitB12-dep_Met_synth_activ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037010">
        <property type="entry name" value="VitB12-dep_Met_synth_activ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02310">
        <property type="entry name" value="B12-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02607">
        <property type="entry name" value="B12-binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02965">
        <property type="entry name" value="Met_synt_B12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00809">
        <property type="entry name" value="Pterin_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02574">
        <property type="entry name" value="S-methyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000381">
        <property type="entry name" value="MetH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01018">
        <property type="entry name" value="B12-binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF47644"/>
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    <dbReference type="SUPFAM" id="SSF52242">
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF82282"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02082">
        <property type="entry name" value="metH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50974">
        <property type="entry name" value="ADOMET_ACTIVATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51332">
        <property type="entry name" value="B12_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51337">
        <property type="entry name" value="B12_BINDING_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50970">
        <property type="entry name" value="HCY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50972">
        <property type="entry name" value="PTERIN_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 19" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 19 21" id="KW-0846">Cobalamin</keyword>
    <keyword evidence="17 19 20" id="KW-0170">Cobalt</keyword>
    <keyword evidence="13 19 20" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16 19" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="8 19 23" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="30" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0677">Repeat</keyword>
    <keyword evidence="12 19 21" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="11 19 23" id="KW-0808">Transferase</keyword>
    <keyword evidence="15 19 20" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Hcy-binding" evidence="24">
        <location>
            <begin position="5"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="Pterin-binding" evidence="25">
        <location>
            <begin position="354"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="domain" description="B12-binding N-terminal" evidence="28">
        <location>
            <begin position="647"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="domain" description="B12-binding" evidence="27">
        <location>
            <begin position="743"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="domain" description="AdoMet activation" evidence="26">
        <location>
            <begin position="894"/>
            <end position="1221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Methylcob(III)alamin binding" evidence="21">
        <location>
            <begin position="753"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="21">
        <location>
            <begin position="1187"/>
            <end position="1188"/>
        </location>
    </feature>
    <feature type="binding site" evidence="20 22">
        <location>
            <position position="245"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20 22">
        <location>
            <position position="308"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20 22">
        <location>
            <position position="309"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <position position="691"/>
        </location>
        <ligand>
            <name>methylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:28115"/>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="20">
        <location>
            <position position="756"/>
        </location>
        <ligand>
            <name>methylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:28115"/>
        </ligand>
        <ligandPart>
            <name>Co</name>
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        <location>
            <position position="801"/>
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        <ligand>
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        </ligand>
    </feature>
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        <location>
            <position position="805"/>
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        <ligand>
            <name>methylcob(III)alamin</name>
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        </ligand>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <position position="857"/>
        </location>
        <ligand>
            <name>methylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:28115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <position position="944"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <position position="1132"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001700"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00001956"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00005178"/>
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    </evidence>
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    </evidence>
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    </evidence>
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        <source>
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    </evidence>
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    </evidence>
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    </evidence>
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        </source>
    </evidence>
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    </evidence>
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    </evidence>
    <evidence type="ECO:0000259" key="28">
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            <dbReference type="EMBL" id="EEZ42447.1"/>
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        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
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    </evidence>
    <sequence length="1221" mass="135207" checksum="AC6BAC3A58293568" modified="2010-01-19" version="1">MVKGLNLLQQRLAEQILIIDGGMGTMIQGYKLAESDYRGERFANWHCDVKGNNDLLVLTQPQIITDIHQQYLAAGADILETNTFNATTIAMADYEMADFSAEINLVAAQLARQAADEWSTPDKPRFVAGVLGPTNRTCSISPDVNDPGFRNITFEQLVIAYSESTRALIKGGVDLILIETIFDTLNAKACAFAVESVFDELGYQLPIMISGTITDASGRTLSGQTTEAFYNALRHVKPISFGLNCALGPDELRQYVAELSRLAECSVSAHPNAGLPNAFGEYDLEPEEMAEHIAEWAQSGFLNLVGGCCGTTPEHIRQMAAVTQNIKPRTPPSIPVACRLSGLEPLNIEKNSLFINVGERTNVTGSARFKRLIKEELYDEALEVARQQVEAGAQIIDINMDEGMLDAKAAMVRFLNLCATEPEIAKVPIMVDSSKWEVIEAGLQCVQGKPIVNSISLKEGKAKFIEQAKLIQRYGAAVIVMAFDEEGQADTRERKVEICTQAYRILVDEVGFAPEDIIFDPNIFAVATGIEEHNNYAVDFIEAVGEIKATLPHAMISGGVSNVSFSFRGNDPVREAIHAVFLYYCFQKGMDMGIVNAGQLAIYDDLPQELRQAVEDVVLNLREDSTERLLDIAEKYRGTGKVEEDRSAQEWRSWPVEKRLEHALVKGITEFIVEDTEQARALAAKPLEVIEGPLMAGMNVVGDLFGEGRMFLPQVVKSARVMKQAVAYLEPFINAEKQAGSSNGKILLATVKGDVHDIGKNIVGVVLQCNNYEIIDLGVMVSCEQILKVAKEEQVDIVGLSGLITPSLDEMVHVAKEMERQGFELPLLIGGATTSKAHTAVKIEQNYHAPVVYVSNASRAVGVCSALLSETQREDFIARLDKEYEVVRDQHSRKKPRSAPITLEQARENCAHIDWQAYQPPQPKSKGIHTIIDCSVATLRQYIDWTPFFMTWSLSGKYPTILRHEVVGEEATKLFNEANVLLDKIEQEGIIKANGVCGFFPANSVGDDIEVYTDESRQHVLTRLHHLRQQTAKPKGANYCLSDFIAPKSSQHPDWIGAFAVTGGIGESELAAQFKAQGDDYNAILIQAVADRLAEAFAEYLHQQVRTQLWGYSPKEDLSNDDLIREKYQGIRPAPGYPACPEHTEKGTLWQLLEVEERTGMSLTESYAMWPGASVSGWYFSHPEARYFAVAQIQQDQALDYANRKGWNEREIEKWLGPNLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-12-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1S2</accession>
    <name>D0Z1S2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phage integrase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_003486</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003486"/>
    <dbReference type="EnsemblBacteria" id="EEZ42453">
        <property type="protein sequence ID" value="EEZ42453"/>
        <property type="gene ID" value="VDA_003486"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0582">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="745068at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DNA_brk_join_enz"/>
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        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0229">DNA integration</keyword>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyr recombinase" evidence="3">
        <location>
            <begin position="184"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
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    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="436" mass="51073" checksum="F012BDBBDB688EB8" modified="2010-01-19" version="1">MKTKVFSMSSGESYSILLGEDGMPLPYHNLFVTLHYRNQSKANATCKSVFEHLRFLEEICQFEKIDLIERCKTGDFLTNREFENIKKHSSLTVESFREMVTRHKSSNVLNIRRKNLETARAKILVNTEGDISPHTTYNRLTVFAQFIGWLEEELFPSKDSTAEFELKKIRGDKFGTSDEALDWGDWKSLEPVQEIRVLDVVRPDSLENPWKSESVRYRNQLIVNMFFSLGCRRGELLKIRVKTDKHQSDIKQRSKNGRYFVMIRSQTDYSDKRKHRPEGKTKGRFVPMDKRLKEMYDNYLIHYRPNASGSEHIKYLFVTHNHKTQTNVALSMAQVNKIFREISEVVGFRVHPHAARHTWNDKFSKFADKRIAEGKTTEAKSEADRQKLMGWTENSKSAKRYAKRHDDKRAMDMALDLQEENSTTINSIVGQYDEYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1Z6</accession>
    <name>D0Z1Z6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Arginine/ornithine antiporter ArcD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_001982</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299086.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001982"/>
    <dbReference type="EnsemblBacteria" id="EEZ40950">
        <property type="protein sequence ID" value="EEZ40950"/>
        <property type="gene ID" value="VDA_001982"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0531">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="527053at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004754">
        <property type="entry name" value="Amino_acid_antiprt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00905">
        <property type="entry name" value="2A0302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="31"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="91"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="126"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="202"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="235"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="278"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="338"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="363"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="391"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="414"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="442"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ40950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="468" mass="50285" checksum="B8E59C92CA323D11" modified="2010-01-19" version="1">MDNKLGLGALSALVVGSMIGAGVFSLPQNMAAVASPAAVIIGWTITGIGMIFLALSFQHLCQLKPEIESGVFGYAQAGFGNFVGFCSAWGYWLSAMLANVSYLVIVFSTLGMFFDKPDMVLFGEGNTWLSVVCSSIVVWAVHALVLRGVKTAAVINSITTIAKLIPMVLFIICTMIAFKWHTFTLDFTGVHFGDEHGLLSQVKSTMLITVWVFIGVEGAVVVSGRARDRRDIGRATILGLLTALSIYVFVTLFSMGVITTPELAAMKNPSMAQVLNQILGPWGGLIIAIGLIVSVTGAYLSWTVLASEAPFIAAKEGMFPKAYQEQNAAGTPVRSLRLTNICIQISLFAVVFAGGTYDSLLNIASEMILVPYFFVGAYTLRLAIEKKDRGSLMVVGVCATIYGLWLLYASGLEHLLLSALLYLPGLMFYVKAKREQGLKPFIGKEMVAASMLTVAAFVAVGMLWQGMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z259</accession>
    <name>D0Z259_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GGDEF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001795</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001795"/>
    <dbReference type="EnsemblBacteria" id="EEZ40763">
        <property type="protein sequence ID" value="EEZ40763"/>
        <property type="gene ID" value="VDA_001795"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2199">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3850">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="268"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="2">
        <location>
            <begin position="556"/>
            <end position="685"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="685" mass="78334" checksum="CB33B5939750F135" modified="2010-01-19" version="1">MLVIAVVPAAMIGGLLLKQQIDVEKNYQTEQLKRLSNTIGQEINYRFYVLSTSLDVLSRDRLLVQGIDNFFLSSHVFATLESLVDNAPLVKSAYLLDKDWDEVENYNGISGIESLKNIQTHLLKQTRLSKNLKGDQWIFNYYDEKLMPNKLNPSERGIVVVVPVYQSTLTEGLKKDPLGYLVVVIPMESLGKMIKPYLSNGEWVELNRNTIDSILFTAGESEHNAPSMSLQRKIELNNEYVAEALNYELIVYMDREYKGDQFTQSLKIFTILSLIAIALGLFGAGMTYRWVSQPLAALMRIVREYSRGNYSVPKRNLRFMEFYSVDNLIQEMSSTIQAQVKNLAVTNQALTNAMKAQEVANVQLSNFNGKLEKKVQEKTEALSTSLKREERRREMMQSLIAFFSKVQTDDFRDVVIQQLKELYPDAEWALKFQYDHKDWSYEDLPLHKLEQLELLQTDQDYFNYRSNQLYHGFNLLDSDNKSLGLLIMQASDLQIDDFEVISIFANQLASTLEGKILNQELKRIAITDSLTELANRKAFDIDFEAYTKRLKRYPERHFGLCIIDVNGLKQANDLHGHKMGDALLISVGNILVSACRNTDKVYRLGGDEYAILLEEGSVAACERLTERLRCERNKHVITTENNQIIKVSFAVGDSCSVSTCVSTMFHVADEAMYQDKMACYAKNKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z283</accession>
    <name>D0Z283_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Serine transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">VDA_001933</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298962.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001933"/>
    <dbReference type="EnsemblBacteria" id="EEZ40901">
        <property type="protein sequence ID" value="EEZ40901"/>
        <property type="gene ID" value="VDA_001933"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="369689at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015171">
        <property type="term" value="F:amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004694">
        <property type="entry name" value="Hydroxy_aa_transpt"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00814">
        <property type="entry name" value="stp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="51"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="142"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="166"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="206"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="254"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="300"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="347"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="370"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="410"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ40901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="429" mass="46284" checksum="E35A3DDD24D24AD9" modified="2010-01-19" version="1">MDTANNTTQNTSSNSKKLGWSKSDTVWVLGLYGTAVGAGTLFLPINAGVGGLIPLIVMALLALPMTYFAHRGMTRFVLSSSNPGADITEVVEEHFGAKMGQLITILYFFAIYPILLVYSVALTNTVESFMQHQLHMTPPARPILALVLILGLMAIVRLGEQLIVKAMSILVFPFVAVLIMLALYLVPYWNGAIFDQVIPTGDSISSIFMAVWLILPVMVFSFNHSPVISSFAVAKQKEYGKDAEVQCSRILGRAHVMMVVTVMFFVFSCVLSLSPADLAEAKAQNVSILTYLANHFDTPVIAYAAPIVAIIAITKSFLGHYLGAGEGLNGIVTKAARSRGKTVSPKALNTFTAVFMLVTTWAVATINPSILGMIESLGGPVIAMLLFIMPMYAIKKVPAMHKYAGKLSNVFVTVIGLISISAIFYSLAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z288</accession>
    <name>D0Z288_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Outer membrane protein A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">VDA_000539</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell outer membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpA family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304666.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000539"/>
    <dbReference type="EnsemblBacteria" id="EEZ39519">
        <property type="protein sequence ID" value="EEZ39519"/>
        <property type="gene ID" value="VDA_000539"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2885">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3637">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="583204at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046930">
        <property type="term" value="C:pore complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015288">
        <property type="term" value="F:porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07185">
        <property type="entry name" value="OmpA_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006664">
        <property type="entry name" value="OMP_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006665">
        <property type="entry name" value="OmpA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006690">
        <property type="entry name" value="OMPA-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036737">
        <property type="entry name" value="OmpA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000498">
        <property type="entry name" value="OmpA-like_TM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00691">
        <property type="entry name" value="OmpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01389">
        <property type="entry name" value="OmpA_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01021">
        <property type="entry name" value="OMPADOMAIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103088">
        <property type="entry name" value="SSF103088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01068">
        <property type="entry name" value="OMPA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51123">
        <property type="entry name" value="OMPA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0626">Porin</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019333" evidence="13">
        <location>
            <begin position="21"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="OmpA-like" evidence="14">
        <location>
            <begin position="207"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEZ39519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="335" mass="36875" checksum="F97ED0152F5EFDAF" modified="2010-01-19" version="1">MSKVRYVLPLALLISGVANAAADNPWYAGFRVGATHYNDISVDGVDSNSAFDRDDMGGGLFAGYNVTPWFAVETGYTWLGRAEFNNDYKMRVDQQAIDLVGKFTWHATDYMGLYAKLGGAYYFSEAKGFGAEKYKDDGVVGTAGAGLEFFLDDHLSARLEYQYYHDVELKDKDVRANWDTHFYGLSLVYSWGAPEPVAEPVYVDQVSVATLEELKLAVPFAFDSSSISTGDAAKLVPFEQRLQEQDAAQIYVVGYTDSKGSEAYNQKLSERRADAVADALRAHLNVDGSRIIAEGRGEADPVASNQTEEGRAQNRRVEIVSPSIDIETVTQVLAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2D8</accession>
    <name>D0Z2D8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">FGE-sulfatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000589</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304799.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000589"/>
    <dbReference type="EnsemblBacteria" id="EEZ39569">
        <property type="protein sequence ID" value="EEZ39569"/>
        <property type="gene ID" value="VDA_000589"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1262">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005532">
        <property type="entry name" value="SUMF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042095">
        <property type="entry name" value="SUMF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03781">
        <property type="entry name" value="FGE-sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="SSF56436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003020002" description="FGE-sulfatase domain-containing protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="domain" description="FGE-sulfatase" evidence="3">
        <location>
            <begin position="65"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="286"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="339" mass="38499" checksum="F7583E63833254AD" modified="2010-01-19" version="1">MKVNSILLLIISANLVACNDSGNTVSSEIISKQEIARIDTNINKLYPDADSKLKQHILNVAVESLESMVFIKGGTFMMGDFKAPCSPLDLKRMDWTPEASCNTALSMTRTGANHQHKVTLSNYSLSDHETTYYETDAFNRSENKPVANQDSRYDKEFPIQDEQLKNRPSSTKSWQEAKDYCLWLGKLTNYPIDLPTEAQWEYAARNRGQNVYFATNSGYVQQIGSRYVDKDGSIHEYTKEQGNYGDFGDIKRWPPNPLGLYDMAGNAGEWVNDWYSKDYYKVSPELNPQGPKTGTEKVTRGWGDSMPLTTTRSHEKPIDSMYYSRRGFRCAVQSPTSIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2G5</accession>
    <name>D0Z2G5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 16">NAD(P) transhydrogenase subunit beta</fullName>
            <ecNumber evidence="7 16">7.1.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Nicotinamide nucleotide transhydrogenase subunit beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">VDA_000616</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 16">The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 16">
            <text>H(+)(in) + NAD(+) + NADPH = H(+)(out) + NADH + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:47992"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="7.1.1.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="6">Heterodimer of an alpha and a beta chain.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell inner membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 16">Belongs to the PNT beta subunit family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.1" evidence="7 16"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304879.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000616"/>
    <dbReference type="EnsemblBacteria" id="EEZ39596">
        <property type="protein sequence ID" value="EEZ39596"/>
        <property type="gene ID" value="VDA_000616"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1282">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="788546at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008750">
        <property type="term" value="F:NAD(P)+ transhydrogenase (AB-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012136">
        <property type="entry name" value="NADH_DH_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034300">
        <property type="entry name" value="PNTB-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02233">
        <property type="entry name" value="PNTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000204">
        <property type="entry name" value="PNTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 16" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="9 16" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="15 16 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-0520">NAD</keyword>
    <keyword evidence="12 16" id="KW-0521">NADP</keyword>
    <keyword evidence="19" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13 16" id="KW-1278">Translocase</keyword>
    <keyword evidence="11 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14 17" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="57"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="119"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="162"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="184"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="210"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="236"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="PNTB" evidence="18">
        <location>
            <begin position="7"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00014581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRNR" id="PIRNR000204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF02233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EEZ39596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="458" mass="48511" checksum="67926190769FDC9E" modified="2010-01-19" version="1">MSAGIVQAAYIVAAVLFIMSLAGLSKQETARNGNYYGIAGMAIALIATIFGPDAQGTGWIIIAMIIGGAIGIYYAKKVEMTEMPELVAILHSFVGLAAVLVGFNTYLDHGDLTGAMLTIHLVEIFLGVFIGAVTFTGSIVAFAKLRGIISSKPLMLPHRHKLNLAAIVVSFILMLIFVKAEGSMIALILVTLIALAFGYHLVASIGGADMPVVVSMLNSYSGWAAAAAGFMLANDLLIVTGALVGSSGAILSYIMCKAMNRSFISVIAGGFGTDGGVASTEEEQGEHREASAEEVAELLKDAKSVIITPGYGMAVAQAQYPVHEITDKLRAQGVNVRFGIHPVAGRLPGHMNVLLAEAKVPYDIVLEMDEINDDFSDTDVVLVIGANDTVNPAAMEDPNSPIAGMPVLEVWNARNVIVFKRSMNTGYAGVQNPLFFKENTQMLFGDAKQSCLDILEHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2H4</accession>
    <name>D0Z2H4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AraC_binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000625</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304904.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39605">
        <property type="protein sequence ID" value="EEZ39605"/>
        <property type="gene ID" value="VDA_000625"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502ZDKA">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1672644at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003313">
        <property type="entry name" value="AraC-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037923">
        <property type="entry name" value="HTH-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02311">
        <property type="entry name" value="AraC_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51215">
        <property type="entry name" value="SSF51215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AraC_binding" evidence="1">
        <location>
            <begin position="27"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="225" mass="24805" checksum="C9C9769E51F96B85" modified="2010-01-19" version="1">MKHAIEFTHHNHPFLHVGSRKKSTHSFFIVVEKGAVLVRLGKNEHLVSAGTGFWLPFDCLHALTALPGTNYYQVDFSIRLTTAVCSHAGFFKVTPLIAALLDELSQTASEQHQWEGPEGRILKVLADKAAQLKVSTKTLSPALAERHHSALTLILNGSKITENSDIKAIESVFNQSVKELESCMLMREAIRLQRSGRKLAQIATELSVPETLLNTLALPILGKPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2I8</accession>
    <name>D0Z2I8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Translation initiation factor SUI1-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_000639</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SUI1 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304940.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000639"/>
    <dbReference type="EnsemblBacteria" id="EEZ39619">
        <property type="protein sequence ID" value="EEZ39619"/>
        <property type="gene ID" value="VDA_000639"/>
    </dbReference>
    <dbReference type="GeneID" id="57342866"/>
    <dbReference type="eggNOG" id="COG0023">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1752091at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11567">
        <property type="entry name" value="YciH_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001950">
        <property type="entry name" value="SUI1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005872">
        <property type="entry name" value="SUI1_arc_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036877">
        <property type="entry name" value="SUI1_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01253">
        <property type="entry name" value="SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037511">
        <property type="entry name" value="Transl_init_SUI1_pro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55159">
        <property type="entry name" value="SSF55159"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01158">
        <property type="entry name" value="SUI1_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50296">
        <property type="entry name" value="SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0810">Translation regulation</keyword>
    <feature type="domain" description="SUI1" evidence="4">
        <location>
            <begin position="29"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="103" mass="11076" checksum="9CF630AC0F9F061F" modified="2010-01-19" version="1">MTLVYSTECGRIKEEKTQPERPKGDGIVRIQRQTKGRKGKGVCVVTGLDVEDTQLKLIAAELKKVCGCGGSVKDGAIEIQGDKRDVIKTALEKKGYTVKLAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2K0</accession>
    <name>D0Z2K0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phospholipid-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000651</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304966.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000651"/>
    <dbReference type="EnsemblBacteria" id="EEZ39631">
        <property type="protein sequence ID" value="EEZ39631"/>
        <property type="gene ID" value="VDA_000651"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1881">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1150223at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00865">
        <property type="entry name" value="PEBP_bact_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008914">
        <property type="entry name" value="PEBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036610">
        <property type="entry name" value="PEBP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005247">
        <property type="entry name" value="YbhB_YbcL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30289">
        <property type="entry name" value="PTHR30289"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01161">
        <property type="entry name" value="PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49777">
        <property type="entry name" value="SSF49777"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00481">
        <property type="entry name" value="TIGR00481"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="159" mass="17345" checksum="415F0B0A724C3426" modified="2010-01-19" version="1">MSNFTLTSNDIFEGQLKDKQFAFNGFGHDGDNISPQLAWENAPEGTKSFAVTCFDPDAPTGCGFWHWQVINIPAETTELEQGASGKLAAGLEMRNDYGFNGFGGACPPEGHGMHRYQFTVWALPVEKLDVPDDASCALVSFMLHGMSLAKSTITTTYVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2L6</accession>
    <name>D0Z2L6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">3-hydroxyacyl-CoA dehydrogenase [isoleucine degradation]</fullName>
            <ecNumber evidence="1">1.1.1.35</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000667</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.35" evidence="1"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305002.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000667"/>
    <dbReference type="EnsemblBacteria" id="EEZ39647">
        <property type="protein sequence ID" value="EEZ39647"/>
        <property type="gene ID" value="VDA_000667"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1601931at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003857">
        <property type="term" value="F:3-hydroxyacyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="252" mass="27332" checksum="238D503DF566212B" modified="2010-01-19" version="1">MEIQDRVVIVTGAGQGLGQMIAVNLAEQGAQLALIDVNEAALRITQDQCHLLNSKAMIYTADVSNEQEVEEAFQHIVEDFGHIDVLINNAGVINDGLLVCKRDGVIRKMPLSQYQKVMDINATGSFLCGREAAAHMIEHDTHGVIINISSVARAGNVGQTNYSASKAAVAAMTVTWAKELARYQIRVAAVAPGVIDTPMIEQMKQEALERLEKNVPAGRVGNAEEVGHALKFILENDYFTGRILEIDGGLRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2S0</accession>
    <name>D0Z2S0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA ligase</fullName>
            <ecNumber evidence="3">6.5.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000721</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="6.5.1.1" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000721"/>
    <dbReference type="EnsemblBacteria" id="EEZ39701">
        <property type="protein sequence ID" value="EEZ39701"/>
        <property type="gene ID" value="VDA_000721"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1793">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1073940at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003910">
        <property type="term" value="F:DNA ligase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012310">
        <property type="entry name" value="DNA_ligase_ATP-dep_cent"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029319">
        <property type="entry name" value="DNA_ligase_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01068">
        <property type="entry name" value="DNA_ligase_A_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14743">
        <property type="entry name" value="DNA_ligase_OB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50160">
        <property type="entry name" value="DNA_LIGASE_A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003020018" evidence="1">
        <location>
            <begin position="28"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="DNA_LIGASE_A3" evidence="2">
        <location>
            <begin position="149"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="303" mass="34479" checksum="F4280F001059A517" modified="2010-01-19" version="1">MSLLYHTNHLTAVAASISLLFSTSAFTTELDSMKASSFTIEHLTALIALENQVDTTNNFPITDYLVSEKLDGIRAIWTGKELLTRSGNPISAPSWFLSKLPSIPLDGELWLGRDHFQELSQIVLDAKPNSIQWQQVRYMLFDLPSITIPFSERYQELLRISKQLDPTFIRVVEQSEISSLAQLEQWLEIIENESGEGLMLHHKNNFYTNGRTKQLLKLKKHQDAEAVIIGYEEGKGKYQGMLGAVWVRTIDNQIFKIGSGFKDTQRISPPPIGSTIQYRFNGYTNKGLPRFARFVRIRNNPDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-02-10" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2U3</accession>
    <name>D0Z2U3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000744</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305230.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000744"/>
    <dbReference type="EnsemblBacteria" id="EEZ39724">
        <property type="protein sequence ID" value="EEZ39724"/>
        <property type="gene ID" value="VDA_000744"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4805">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="520320at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010281">
        <property type="entry name" value="DUF885"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33361">
        <property type="entry name" value="PTHR33361"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05960">
        <property type="entry name" value="DUF885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="675" mass="76274" checksum="D9549EE7CDADD848" modified="2010-01-19" version="1">MKKYSLPYTFAITSLLMLSGCNDDTTVVEQPKDTEPPATQLRTVLSNYQNATHTLDNTHFGQVTDQMASSRQGIDRMYLDKLEQINRDALSDEDKIYYDTFQFDRNLAIRGASFPNPRFGNFDIPITHFYNYIDWNASAAGSKQESPEAYHKHIQVLREFTSWVNNLQSQYSLAIIDRAQLPKILTTRLINSTVEAMAINGQPYGLLEIGLNDIKASGNADYSDEFIAEYQKAVNDAQRAVDNIINFLQTDYFKSARGTNDITDTNIGWGDLPNGQAWYQWQLDRNSTTGKSAMELNKLGEDLVADAKAEMIRVAQLIIKKRGETIKAEWRNPDGVVEERTFNLVNADESVNLDEFFDYLNSEQFFYGRDGRTISGTPYANLCKAASDQTACEAALIDYNTFKNDANNIVASYFKPIKTDYTIVPVPANREKYDGVASYGGNEFNLNTNPNYSLQKWNVSTLLLHEAAPGHHFQNAYSIEYPPKDKPDYIKGVSYTAYAEGWALYTEWLGLKMGIYGELNAEGKPTFINATGMCKPDLDYTHFQGGIYNDAEECNALQYFGSLNEAQLRNMRLAVDTGIHAKGWSIQNAQNYMNQNSALGDGDIESESFRYAAYVGQAVSYKSGYLVIMEMLTLAQNELGNKFDWASFHDQLLKYGDQPMEVVETSIKNWIKTQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z338</accession>
    <name>D0Z338_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">TonB-dependent receptor protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">VDA_000839</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305494.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000839"/>
    <dbReference type="EnsemblBacteria" id="EEZ39819">
        <property type="protein sequence ID" value="EEZ39819"/>
        <property type="gene ID" value="VDA_000839"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4206">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="514956at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039426">
        <property type="entry name" value="BtuB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30069">
        <property type="entry name" value="PTHR30069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="4" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0675">Receptor</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0798">TonB box</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Plug" evidence="10">
        <location>
            <begin position="66"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="9">
        <location>
            <begin position="162"/>
            <end position="662"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ39819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="663" mass="74012" checksum="59BEC04C77ACE602" modified="2010-01-19" version="1">MKYSITLLTLLPCLSYGSEVTTLDEVLVVDHNSAVLHPTRMAQEKIIRNQPGGGSLITDKPIISARPEDALSQQAGVVVQSFSGGNDQTRLSVRGSGIQSFPPTRGLAIFQNGFPINDADGSFNLGLVNFSNTQFISVLRGANALRSATSSLGGEIELFSNQGRQNNQVSYQLGSFGRQNTFATVGGENSDGDINLSANLDDYDGYRTQSSSHRKGLSLNSTYFLSDHLSNSLYVDLAKLRFNIPGPLSKDQLEDDPTQANPMYAKAKPFRHLENIRIGDRLSFAQGQQRYDLQLWYSHTFDDFKTPMSRYISHINTYGSSLSADIKLNDQHHLTSYLSFDQSDIDRSFYAKNNASMGVYNLTANNLRFNVRDHYQIDRNFSVIAGTDFALSHRNGESKHQNLDQLYRTFAPKIGALYQWNAANTLFTNVSYSAEVPTFWDIQDTKGQNVILKPLEQQKATTYEIGARGSLLDSWYYDLAIYHAIVDNEIVLTYDDSGTQMGAFNYQGTSWHQGVELALNKTQHFGSTELDYNLTWTFNRYTFQSGLYQGKHLPTIPDHIITAQIKAKHGKFGAGADMNYVPTSTPVDYVNSGRQELDPYLIVNVGVDYQPITDLTLWAKVDNILDENYAAMSVARDKVGSSKQPTQFPGLGRSVNIGFQYKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z365</accession>
    <name>D0Z365_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 9">Class B acid phosphatase</fullName>
            <ecNumber evidence="5 9">3.1.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">VDA_000866</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>a phosphate monoester + H2O = an alcohol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:15017"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:67140"/>
            <dbReference type="EC" id="3.1.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9 12">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="9 12">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 9">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the class B bacterial acid phosphatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.2" evidence="5 9"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305572.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000866"/>
    <dbReference type="EnsemblBacteria" id="EEZ39846">
        <property type="protein sequence ID" value="EEZ39846"/>
        <property type="gene ID" value="VDA_000866"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3700">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1258380at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07499">
        <property type="entry name" value="HAD_CBAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005519">
        <property type="entry name" value="Acid_phosphat_B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010025">
        <property type="entry name" value="HAD-SF_ppase_IIIB_AphA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03767">
        <property type="entry name" value="Acid_phosphat_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017818">
        <property type="entry name" value="Acid_Ptase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01127">
        <property type="entry name" value="C1.3:_Acid_Phosphatase_Like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01672">
        <property type="entry name" value="AphA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 9" id="KW-0574">Periplasm</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 13" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019367" description="Class B acid phosphatase" evidence="13">
        <location>
            <begin position="26"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="11">
        <location>
            <begin position="142"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="10">
        <location>
            <position position="74"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10">
        <location>
            <position position="76"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR017818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR017818-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR017818-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR017818-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEZ39846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="241" mass="26904" checksum="03A0C3D5EF08C7FC" modified="2010-01-19" version="1">MNKSFLSLVLGTVLASSFVIGSAYADPKLAGTETGYSSTQLMQMGEQQAKLHWVSVADIEKSLEGKPPMAVGFDIDDTVLFSSPGFYHGQQVFSPNGYSYLKNQKFWNKMNCEWDVFSLPKDIGKELIAMHQKRGDSIYFITGRDPSTCKEITSDYLQKVFNIKHMNPVVFAGSSKTEYTKTKYIKDNHIKLYYGDSDGDIISARHAGAEGIRIIRASNSSYKPIAQNGIYGEKVVENSQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3A5</accession>
    <name>D0Z3A5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Putative pyruvate formate-lyase 3 activating enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_000906</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the organic radical-activating enzymes family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305685.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000906"/>
    <dbReference type="EnsemblBacteria" id="EEZ39886">
        <property type="protein sequence ID" value="EEZ39886"/>
        <property type="gene ID" value="VDA_000906"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1180">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1141206at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040074">
        <property type="entry name" value="BssD/PflA/YjjW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034457">
        <property type="entry name" value="Organic_radical-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012839">
        <property type="entry name" value="Organic_radical_activase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001989">
        <property type="entry name" value="Radical_activat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30352">
        <property type="entry name" value="PTHR30352"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000371">
        <property type="entry name" value="PFL_act_enz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01118">
        <property type="entry name" value="activating_enzymes__group_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01087">
        <property type="entry name" value="RADICAL_ACTIVATING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="10" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="9">
        <location>
            <begin position="11"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ39886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="313" mass="35313" checksum="2FE8E8130F16F2F3" modified="2010-01-19" version="1">MYFNIQRFSTHDGDGIRSILFLKGCSLSCPWCQNPESRSEKYSLLFDQRSCMEDCQLCVSAYQATTQSTAGGETVGDGIQRIDNQIIINRKAIKEDQLITLRNVCPTQALTVCGEEAKSDMLFDILMKDKAFYDQSQGGVTFSGGEPLMQADLVAELAQRLHDNQVSTAIESCMHVPWKNVEKAAPHIDCWLADLKHTNEEKFLSWAKGSLKRIKDNFRKLAPIAKRIVIRVPVVPGFNDTIEELKDIIDFAASLESCQELHLLPYHTLGINKYRLLDMPYECSDKPLNKPELLESAMQYASENTQLNVIVRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3D2</accession>
    <name>D0Z3D2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phg_2220_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000933</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305761.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000933"/>
    <dbReference type="EnsemblBacteria" id="EEZ39913">
        <property type="protein sequence ID" value="EEZ39913"/>
        <property type="gene ID" value="VDA_000933"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1778696at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011741">
        <property type="entry name" value="Phg_2220_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09524">
        <property type="entry name" value="Phg_2220_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phg_2220_C" evidence="2">
        <location>
            <begin position="180"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="283" mass="31405" checksum="4D4AFF22D29D5245" modified="2010-01-19" version="1">MHKLLFELLGQGANLSIPRLFVRMCSGSYNHAAVLAQLVFWSNKSSRTDGWFYKSQVELGGELELSRDQVKRSVKYLTTNFGNAIHTKLKKANGVPTTHYFIDIKELLSLASKEIKEDPKPSGEVVKLSGQDSPMPGMGEPTQSITDPNHIRSTDLKDSLSSKHDKASTKSTNLEIAKTVIAFLNEATGSKFQCCKSNLNYINGRISDGYTLEDLCQVIAHKKIEWGSDAKMSQYLRPCTLFQPGKFAGYLQSAKVANLHPGDRPVSLADFDDTTWGQDLGIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3G2</accession>
    <name>D0Z3G2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA-directed DNA polymerase</fullName>
            <ecNumber evidence="1">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_000963</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="1"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305846.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000963"/>
    <dbReference type="EnsemblBacteria" id="EEZ39943">
        <property type="protein sequence ID" value="EEZ39943"/>
        <property type="gene ID" value="VDA_000963"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0847">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1985371at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006054">
        <property type="entry name" value="DnaQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Exonuclease_RNaseT/DNA_pol3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00573">
        <property type="entry name" value="dnaq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Exonuclease" evidence="5">
        <location>
            <begin position="58"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ39943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="249" mass="28139" checksum="A0FE517280FD91E6" modified="2010-01-19" version="1">MIRLFSSAKEDEPLLDTSTTPNWPERFVQLATESKDQRLKQFYEASCVAGDTPLKEVPFVALDLETTGLDSQQDQIISVGLVPFTLDRIYCRQSAHWVVNPHRLLNEESVVIHGITDSEVQDAPDLRVILEQVLQALAGKIVVVHYKNIERGFLNQALLKRLGEGIEFPVVDTLDLEAAIQYRQCRGFFNRLKGKKPGSVRLGHARERYGLPTYQPHHALTDALASAELLQAQLAYYFTPNTPISEVWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3G8</accession>
    <name>D0Z3G8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Hypothetical MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_000969</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305867.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000969"/>
    <dbReference type="EnsemblBacteria" id="EEZ39949">
        <property type="protein sequence ID" value="EEZ39949"/>
        <property type="gene ID" value="VDA_000969"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1384345at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="75"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="104"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="204"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="241"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="272"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="296"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="328"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="358"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="9"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="395" mass="41445" checksum="B9ACEFD33F9C8D81" modified="2010-01-19" version="1">MNKEKMPLQVWILTLAAFAIGTAEFVIAGILPQVANSLSITEGQAGYLISAYALAIVFGGPLLTIYLARFNKKAVLAGLMVLFILGNVLSAFAPNYFVLMVSRVVTGLVQGPFYGIGAVVATNLVSEKMAGRAVGQMFAGLTLANVLGVPGGTWIGLQFGWHTTFLTVAAFGLVALFSITSVIKSTGHGEAKDVKAQLAAFKNPMLLISLAITVFAWSGFMTLYGYIAPIAMHITGFGESAVTWILVIVGVGLIVGNTMGGRSSDKNLQKASMFWASAMIVSLVLVGLTVDSKVLFIATAFVFGIASFANVPAMQLRVMKHGGEGQELAATANISAFNLANAFGGFLGGMVLDSQMGAGMIPYAAIIVPLIGLLFIAKANRKESKQVELAPSFNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3H0</accession>
    <name>D0Z3H0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-ethylmaleimide reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000971</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000971"/>
    <dbReference type="EnsemblBacteria" id="EEZ39951">
        <property type="protein sequence ID" value="EEZ39951"/>
        <property type="gene ID" value="VDA_000971"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1902">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045247">
        <property type="entry name" value="Oye-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893">
        <property type="entry name" value="PTHR22893"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxidored_FMN" evidence="1">
        <location>
            <begin position="8"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="68" mass="7734" checksum="A16E88EA0086688C" modified="2010-01-19" version="1">MMATYYKQRADEVLEKGYADLVAFGRPFVSNPDLVARLQHQQPQAELDGFTLFGGNEYGYTDYSMCSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3Q3</accession>
    <name>D0Z3Q3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001054</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306096.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001054"/>
    <dbReference type="EnsemblBacteria" id="EEZ40034">
        <property type="protein sequence ID" value="EEZ40034"/>
        <property type="gene ID" value="VDA_001054"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1414">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="370329at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014757">
        <property type="entry name" value="Tscrpt_reg_IclR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005471">
        <property type="entry name" value="Tscrpt_reg_IclR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09339">
        <property type="entry name" value="HTH_IclR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01614">
        <property type="entry name" value="IclR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00346">
        <property type="entry name" value="HTH_ICLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51077">
        <property type="entry name" value="HTH_ICLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51078">
        <property type="entry name" value="ICLR_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH iclR-type" evidence="3">
        <location>
            <begin position="7"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="IclR-ED" evidence="4">
        <location>
            <begin position="70"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="244" mass="26787" checksum="E475DB43B15EE802" modified="2010-01-19" version="1">MIVTYSLSANEKLLQVLIHIAASNKPLHAQQLSNETGMPISSLYRYLALLRGWNLVEENHSQNTYSAGPAALQLQRNFHTHSPLPDGVRPVLKRLQQQTGEMSAYMVPVGFNALCVDSIDSPYALRCSYEKGQSQPLIRGASAKVILAHLSLSRQLMILAHYGITDQFEIDRWMTELELIKQDGFALSTSEIDPGVSGVSAPVFIGNKVAGAVSVMAPAERINSRKNKIVMCVLQAARALPPQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z403</accession>
    <name>D0Z403_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001156</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001156"/>
    <dbReference type="EnsemblBacteria" id="EEZ40134">
        <property type="protein sequence ID" value="EEZ40134"/>
        <property type="gene ID" value="VDA_001156"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2425">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="543" mass="60707" checksum="CF5386712CA73D09" modified="2010-01-19" version="1">MLSEVATSAFTRFVLVKLATKATKYFIDDNFRSKVTPVEGSVVYSDLFTGVEHSGIYIGDGKISNIVVTGTFESEVKLDSASTFVDSSKLHSKIYVSCNSNGAVGHQMVADEAESRIGDKAFYGLIIQNCHEFSRKCVEKAPENLNLGLWDKVTSSFEIEDTWEFTIGALKRSAKKHMRATKWRLWEQGQGNSISESELKQIYHQLDNTPLDSQTLDAIIHSQSELERYSKEIEDENLPASALKNIDQYKTQLAKLKYAGEKATKLSKGLGYSFTYNELKDIKDIDFSSLAQELASNQAITDIVTTLGRAYISEKTNHKQVKRINTNEVYGTHKSADISRVLPSDLALLENEDLEYLFYAKLLESNLSTYKLLGHHIDFEKENDTEEDKGPIVTCLDTSGSMSGIPILKARALLLAIHSIITKEKRELYVLLFGSRGQVKELYLSETSSSGLLPFICKEFSGGTDFETPLKRAINIIEHKEKFNKADILMITDGECNVSDNFQRMLVAKKSQLDFSVQTVICTGSFANTHQVTDGFSDRIVGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z416</accession>
    <name>D0Z416_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Selenocysteine-specific translation elongation factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001169</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306401.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001169"/>
    <dbReference type="EnsemblBacteria" id="EEZ40147">
        <property type="protein sequence ID" value="EEZ40147"/>
        <property type="gene ID" value="VDA_001169"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3276">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="244339at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001514">
        <property type="term" value="P:selenocysteine incorporation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015191">
        <property type="entry name" value="Elong_fac_SelB-wing-hlx_typ-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004535">
        <property type="entry name" value="Transl_elong_SelB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09107">
        <property type="entry name" value="SelB-wing_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00475">
        <property type="entry name" value="selB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="3">
        <location>
            <begin position="9"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="607" mass="67377" checksum="A3A9F5A862A3C6DF" modified="2010-01-19" version="1">MVASNSSVPYQAVIGLAGHVDHGKTALIQALTGMMTARAHEQALGMTQDLGFAHFQDDSGNTIGVVDVPGHERYLRNMVAGVWHLNVLLLVIAADEGWMPMTTSHVQVAHAMGIEHIVVCINKKDKVDASQLADIEDQALDNVMDLTGLLPEIVAVSALNHDNISTLRQLLISTVNESLAAQSTISSQLQLYVDRAFVVNGIGTVITGTLAHGTINLGDKVRCYPSGIVGTVRSIQAYHQSLQTISGTCRVALNIKGVSRKDIGRGHLVVSANDTMTLADQCIIRINKNDAKLKEKKQRQVEAAIGTWHGVAKVSYLPQTQLARVVFNHPIPLFFGQRLALIQKGGSRLMHGGEVVWHDFIAGHQKRALYQALDALPVDLNIEHQRQLRLTLQGYFEPIVDSSEGEYIPTCDQTYLAPYCFASHWLDAWIQNVLTLLQDGDAMATNELSSRFKLDDAVVNTIMQHLKQQQKVHLSYGKWRFGAGDNEDDLPAEALVILQQIRQFGKAGLELNKVTVAGGKKWLRQLSHQKYITALDDTIYFDMGLYHNLVKEILAGHQVYDRISMGEIKDRTELSRKYSIPLANRMEKDGWVRRDGDERVILKIWQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z496</accession>
    <name>D0Z496_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000352</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304126.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000352"/>
    <dbReference type="EnsemblBacteria" id="EEZ39334">
        <property type="protein sequence ID" value="EEZ39334"/>
        <property type="gene ID" value="VDA_000352"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4340">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="597962at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018724">
        <property type="entry name" value="2OG-Fe_dioxygenase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10014">
        <property type="entry name" value="2OG-Fe_Oxy_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="210" mass="24350" checksum="E2D6AB088C724679" modified="2010-01-19" version="1">MNNTFLIEAFQTPPSVAENLIPYFEDLPQDQYVTQHNRYRTYARFSYNAHDFSRLAHHNFCQSSEINRAVGDIERNFAPMSEELINTPEFQHLLSSFAHYIDVDLTHRIIDVHQIRVTCNDHTTSSAAPEGIHQDGFEFVGIYCVQRKNICGGFTQLFTSPVDQHPHLNTVLEENQFIIINDRHFYHFISETLASTHDEQGVRDVFVFTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4F3</accession>
    <name>D0Z4F3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_000409</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304287.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000409"/>
    <dbReference type="EnsemblBacteria" id="EEZ39391">
        <property type="protein sequence ID" value="EEZ39391"/>
        <property type="gene ID" value="VDA_000409"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="692375at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="145"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="166"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="228"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ39391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="418" mass="47608" checksum="2066B9C40DEB624F" modified="2010-01-19" version="1">MKIKSAKQLTFTYFSIVAFAIIAIHFSIFESTIEDLEMFNAQNRLDMALESVQQNLPQDELEHNNPYTSFYFGKANIPSDIHLPENLPFNKAVEVYKPSQDELETEYFVMRSKVTYQGKEQEVYIFNIDPIFERSEEQMMDSQSYQMLLTLGLLLVSLFAVLRISVRLTSPLSSLSKQLQNRAHNDFTPIQLPSSGQTRELVQLVESLNDYQQQITDLLERERAFNRFASHELRTPLMVIKGGLTLLGHSQQPEFVERQRNRMLPAVDEMQEYVQTLLSLTRDEQLTETPWQIREDLIHSLISSYQQLLDGKTVKIDVVANGEPTVNAPLPAVKILLGNLIKNAFTYTEQGRITIILNTSNVVISDTGVGIDPDAENGQKGYGLGLLIVKDICRKYNWSVELSNNRANGCDATVDFIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4L4</accession>
    <name>D0Z4L4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ADP-ribosylglycohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000472</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304458.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000472"/>
    <dbReference type="EnsemblBacteria" id="EEZ39452">
        <property type="protein sequence ID" value="EEZ39452"/>
        <property type="gene ID" value="VDA_000472"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1397">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1661477at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4080.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005502">
        <property type="entry name" value="Ribosyl_crysJ1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036705">
        <property type="entry name" value="Ribosyl_crysJ1_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03747">
        <property type="entry name" value="ADP_ribosyl_GH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101478">
        <property type="entry name" value="SSF101478"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="344" mass="36991" checksum="98C7CDAE595BF111" modified="2010-01-19" version="1">MTHADIVTLIHTQDRILGCLYGQALGDTMGMPSELWPKSRVEQHFGWINTLLDGPAENIAANEFKAGEYTDDTAQCVALMDAIIEAKGDIEPYLIASHIMAWAKRINAFEKNILGPTSKAALNALDQGISFEEIEANGVTNGSAMRVSPIGCLLPTYDRAAFINGVRLSCLPTHKSDIAIAGASVIAWAISRAIEGASWNIIKQEIIPLANETQQTFESTFSPLLGERIQYALNVVASEHNEQQGLTNLYQKVGAGMDIIESIPTAIALVELSNTDPHLCAELAANLGGDTDTIGAMATAICGAIHGINRISNDTVDQINQANHIDFTPYAAALCQFREANLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4X4</accession>
    <name>D0Z4X4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000207</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39191">
        <property type="protein sequence ID" value="EEZ39191"/>
        <property type="gene ID" value="VDA_000207"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3316">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032874">
        <property type="entry name" value="DDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13610">
        <property type="entry name" value="DDE_Tnp_IS240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_IS240" evidence="1">
        <location>
            <begin position="47"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="218" mass="26021" checksum="51B6883D83CA0B10" modified="2010-01-19" version="1">MSYANISDMLAERGSSVNRSTIYRWFIEYSPALRKKLRRYQFIRVDSSWQLDETYVKVKGKWFYLYRAINKQGETLDFYFSKKRNKYSAYQFLKRCLKYYPLEKKPKTLNTDKHSSYGNAIARLKKEGYLRKDVKQRQVKYLNNGIESDHSPIKKLIMATSGFKVQKRAWATLQGFESVRMLNQGQFDFWLRHDEPKTKVLDRSAFMNSLFNVDAIYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z569</accession>
    <name>D0Z569_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH_7 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000119</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39103">
        <property type="protein sequence ID" value="EEZ39103"/>
        <property type="gene ID" value="VDA_000119"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502Z9K1">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000150">
        <property type="term" value="F:DNA strand exchange activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006120">
        <property type="entry name" value="Resolvase_HTH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02796">
        <property type="entry name" value="HTH_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_7" evidence="1">
        <location>
            <begin position="125"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="158" mass="18011" checksum="AA4AE9AF19A325AF" modified="2010-01-19" version="1">MTFDLEKATGKTVVKSAVLREVANSGHVEKYVFHRYSNQLANIGLHTEYLVLDGKSLKRLKVEFTTLSNNLESFTIHCHRSRRYEEKRLAASKRGIELTQREKGKFGRPKGSTVSIDDFLMKHSDIVTRLERGLSINQTAEIMGKGRSTVKRVKEAMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z588</accession>
    <name>D0Z588_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">IncF plasmid conjugative transfer DNA-nicking and unwinding protein TraI</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000138</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306956.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000138"/>
    <dbReference type="EnsemblBacteria" id="EEZ39122">
        <property type="protein sequence ID" value="EEZ39122"/>
        <property type="gene ID" value="VDA_000138"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0507">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="961809at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014059">
        <property type="entry name" value="Conjug_relaxase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014129">
        <property type="entry name" value="Conjug_relaxase_TraI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040668">
        <property type="entry name" value="TraI_2B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014862">
        <property type="entry name" value="TrwC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18340">
        <property type="entry name" value="TraI_2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08751">
        <property type="entry name" value="TrwC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02686">
        <property type="entry name" value="relax_trwC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02760">
        <property type="entry name" value="TraI_TIGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TrwC" evidence="2">
        <location>
            <begin position="36"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="TraI_2B" evidence="3">
        <location>
            <begin position="696"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF18340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="1980" mass="221781" checksum="BDC171ED2F071515" modified="2010-01-19" version="1">MLSLSSLRGGASGASKYYLEEEKQLHLNQPQFTLKTDTQPTKDSPLPPTDNPTANYYLAEQSGTKKTTQWYGKIAEKEGILGHEIEHQKLEAVLNGQLNNDQTPRAHSDTRRTGYDLVFSAPKGASILALVYGDTRIIDAHNAAVKTALDLLEQDTAQAKVTENKEGRFENTQNLLFGLVQHKTNRNNEPQLHTHALQANMTYDNQGNLKNLASSFVQNGFETQGTYERILENAKYYGMAYHSELGRALEGMGFAIKSLGNGQIDIDGIPTEVIEANSTRREEILEYANETGHSSGKSRMIAAHQTRKAKTYTPEDSLVKEWQTKNEALKFDGLAFVAASYNGEHRKDNDISVPDKELQQAIDNSISYLSDRLSAFGYEKVLVTALDKFAPKAITQMGELKQALDNKIKHGDLIALDDKQSLFTTQEQVDREAKLIESTQKRTHGLRVHADSTALNELNLKADTKKTLADILASTKQVNVVNLSGSSKQLSESLLHVSENSGKSIHFITPNKLVKQQTEQQVRRQAFSVTQWVKNAFRPDVVHTAYQYLNQAERRQKTKDSILVVEHANQLGVKETQQLIDLAQRQGNKLVFLNHTKRSQGLRAGNAMDVVQKGNVQTHTWQGAQLAQTHIKTSEVDKKERHQILAERYQELSKQERSETQVLTTNKGDNDNLNRVIRHQLDKSGQLSEKRVEIPTLNPVFMSPEQQRSIKSYQKGMVISQVNDGKVQQYTVEKVNSRAQTLQLLDSDNNRSYLNVKESSTPYFVSQPDKIEVATGDRLRINGDVFRTDLKQNDTVTVEKIGWMGLSLTDDNGKGHLVPLSYLEGSALSYGYANTLNNAAHGKTTTLVEMQSYTASKETLYELMQQGSKQLHIFTDNQEKLEARMEKSHIQPSSMARVMASTQSLDKYVNAQTAETLQSDVTMAVQALLDQQAPKPLIEQAVNFALDHVSEQQAGFKHSELVVEAIRFAMDEKGTTVLESEIHNKLNELQQQDSVLSAQFSDGTRWTTKEAIDTEKRILTRLDAGKGQVASYASERQADAYLAQQDWMTDGQKEAIKLMATTNDRYTIVQGFAGVGKSTMLEQGKTLIEQTQALHGNANIDVLGLAPTHAAVNELKEKGIPAQTTQSLLKDLLTGDTTPDKYKNTLFLLDESSMASNAQFDAFTALVNNSGARATLLGDIYQLQSKEAGKPFELAYRSKSVDTVVMKDIQRQQTPELLSAVQNVINQQSESMLEAIKQQSPLPGSHHNQTVVSTYNETGNSAKDREVAKEELYQSAAAEYLSRTPESRENTLMIAYSNRERDILAGLIRKGLKEMKELLDKSDTPVTRLRGIGTTKEELKTMMPYKAGLIINTGRDTYLHIDSIDRRNELLMVTNMTTGEQTSFIPARHDHKMTTLWSSSEMPLTSGDKITWRKTDKELGLTGNMDLTVSDINKDTIMLSNNDGKHVTLSLSDMKSSHWDYRYTKTADMAQGSTTNHVISVIDSEAKLTNLRRAYIDISRASQHAMIFTDNEKGLMRSWLNHFDNNSSAIETVNKTYHSNERHFDTQSIPRENPKYQQHGEFKLSLYAKDLAQQLTPYTESLAIELLGQPNNSKSDNDYLAFGQGQSHLKVTLTGEYRGYFRDWTTGDKGNLINLIMSAKSFSFKEAVNFAEQILTEPENHNLIENEKHDKLVDTLPKQMSELKERAMSYFEQGAEIKETIANIYINNQTYHDFESHPALRFHEQVYSSETKSTHPALLAALTNNKGEIEAIEITYLNKDGDLADNLTTPKRLMGNKSGHGIVLNDGTLPDISVVAIGLENGISLLGSNTHDVDIVAVTNAHDLRTLDTKALREQIIIMTSEHQLSNQNLISDITDKLTAQGHNISIVKETMDGLSSQDIGIYISDKVNDDIAELKGEHEIDTKKIEQLVDDISKSQEFSDKEIASLLDVIEPKDIEHANHLANETVDKSLAEYDLHQEQTEKELAQEKELEKELDYPLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5I2</accession>
    <name>D0Z5I2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hypothetical type IV pilin PilA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000089</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000006">
        <property type="protein sequence ID" value="EEZ39034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005307202.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000006.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000089"/>
    <dbReference type="EnsemblBacteria" id="EEZ39034">
        <property type="protein sequence ID" value="EEZ39034"/>
        <property type="gene ID" value="VDA_000089"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4969">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1902406at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="309" mass="34778" checksum="52A45652C0F38883" modified="2010-01-19" version="1">MKKQKGFGLIETIMALAILGIVSTMIIKGVNKYNQIQQAKAYAAHIERVINQLQKYQYKKVTIDHISPSSKNVWPTNLDGLMIASQFWPQCSLVDEQAHRCVRPDSVPWTTRKLGYSVTSTNPTKAELILPSPPTEWASPLKRLPFAVTQGNGDIKISVEDPLLSQVFDGLQQDWLKKDGSTELTKTWDVGNQSILNAKKFSVRTQTGTQLRIDAGTVKEFLARHNDRVYKSSWSCPEGLRQTIHVSAHAPMAPNSSTEYVGISNFKPYAIDRGSFYELNFDYNAKIKSTGKWARMHSGFLNVRLNCDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVJ0</accession>
    <name>D0YVJ0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0260 protein VDA_001570</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001570</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0260 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298300.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001570"/>
    <dbReference type="EnsemblBacteria" id="EEZ40544">
        <property type="protein sequence ID" value="EEZ40544"/>
        <property type="gene ID" value="VDA_001570"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2983">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00676">
        <property type="entry name" value="UPF0260"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005358">
        <property type="entry name" value="Puta_zinc/iron-chelating_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008228">
        <property type="entry name" value="UCP006173"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37421">
        <property type="entry name" value="PTHR37421"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03692">
        <property type="entry name" value="CxxCxxCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006173">
        <property type="entry name" value="UCP006173"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="145" mass="16941" checksum="403B58C602E6DA18" modified="2010-01-19" version="1">MTQFWQEKNLTEMTEQEWESLCDGCGKCCLHKLIDDDTDAIYYTNVGCSLLDNKTCSCKDYANRFESGEECLKLTRERIDEFVWLPETCAYRLLAEGKSLPEWHPLLTGSKDAMHDAGESVRDQFVYEIDVIDWEDHILNHPHRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVK6</accession>
    <name>D0YVK6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Flavodoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_001598</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Low-potential electron donor to a number of redox enzymes.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the flavodoxin family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298352.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001598"/>
    <dbReference type="EnsemblBacteria" id="EEZ40571">
        <property type="protein sequence ID" value="EEZ40571"/>
        <property type="gene ID" value="VDA_001598"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0716">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1961680at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001226">
        <property type="entry name" value="Flavodoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010086">
        <property type="entry name" value="Flavodoxin_lc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038996">
        <property type="entry name" value="FldA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01752">
        <property type="entry name" value="flav_long"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00201">
        <property type="entry name" value="FLAVODOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0249">Electron transport</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4 5" id="KW-0288">FMN</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="6">
        <location>
            <begin position="3"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR038996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="162" mass="17881" checksum="358B30C9699AF039" modified="2010-01-19" version="1">MNIGIFFGSDSGQTEAVANLIANKLNLTAQDIQDCDDTSFDDYDLLILGTPTVNYGEMQPDWDYFVPTLEDMDLAGKKVALFGLGDQVDYPDSFQDAMGDLAELIEQAGGELVGFTSTESYQFNDSRAQRGEQFVGLALDTDRQSELTEARIDAWLKQLQLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVM8</accession>
    <name>D0YVM8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Alkyl hydroperoxide reductase C</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Peroxiredoxin</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Thioredoxin peroxidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_001609</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298372.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001609"/>
    <dbReference type="EnsemblBacteria" id="EEZ40582">
        <property type="protein sequence ID" value="EEZ40582"/>
        <property type="gene ID" value="VDA_001609"/>
    </dbReference>
    <dbReference type="GeneID" id="57342313"/>
    <dbReference type="eggNOG" id="COG0450">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="892697at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051920">
        <property type="term" value="F:peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024706">
        <property type="entry name" value="Peroxiredoxin_AhpC-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019479">
        <property type="entry name" value="Peroxiredoxin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10417">
        <property type="entry name" value="1-cysPrx_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000239">
        <property type="entry name" value="AHPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="8">
        <location>
            <begin position="3"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine sulfenic acid (-SOH) intermediate" evidence="7">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00032077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000239-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ40582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="201" mass="22227" checksum="36A4EF6BE7DB4201" modified="2010-01-19" version="1">MGVLVGRPAPDFTAAAVLGNGEIVDSFNLAQHIQGKPAVVFFYPLDFTFVCPSELIAFDKRYNDFKEKGVEVIGVSIDSQFSHNAWRNTAVEDGGIGPVQYPLIADTKHEICQAYDVEHPEAGVAFRGSFLIDKEGVVRHQVINDLPLGRNIDEMLRMVDALQFHEKHGEVCPAQWEKGKEGMNASPEGVAKYLSEHTEDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVN1</accession>
    <name>D0YVN1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 14">Dihydrolipoyl dehydrogenase</fullName>
            <ecNumber evidence="3 14">1.8.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">VDA_001196</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>(R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + NAD(+) = (R)-N(6)-lipoyl-L-lysyl-[protein] + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:15045"/>
            <dbReference type="Rhea" id="RHEA-COMP:10474"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="EC" id="1.8.1.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12 14">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="12 14">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="14">The active site is a redox-active disulfide bond.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.4" evidence="3 14"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297617.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001196"/>
    <dbReference type="EnsemblBacteria" id="EEZ40174">
        <property type="protein sequence ID" value="EEZ40174"/>
        <property type="gene ID" value="VDA_001196"/>
    </dbReference>
    <dbReference type="GeneID" id="57339949"/>
    <dbReference type="eggNOG" id="COG1249">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="267896at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004148">
        <property type="term" value="F:dihydrolipoyl dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006258">
        <property type="entry name" value="Lipoamide_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012999">
        <property type="entry name" value="Pyr_OxRdtase_I_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="SSF55424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01350">
        <property type="entry name" value="lipoamide_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00076">
        <property type="entry name" value="PYRIDINE_REDOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6 12 14" id="KW-0274">FAD</keyword>
    <keyword evidence="5 14" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8 12 14" id="KW-0520">NAD</keyword>
    <keyword evidence="12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 14 17" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10 14" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="16">
        <location>
            <begin position="8"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_dim" evidence="15">
        <location>
            <begin position="348"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="11">
        <location>
            <position position="446"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="183"/>
            <end position="190"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="273"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="314"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="320"/>
            <end position="323"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="13">
        <location>
            <begin position="45"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EEZ40174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="476" mass="50910" checksum="3F4849689E5EF7C8" modified="2010-01-19" version="1">MSKEIKAQVVVLGSGPAGYSAAFRCADLGLDTVLIEKYSTLGGVCLNVGCIPSKALLHVAKVIEEAKAMAAHGVVFGEPQTDITKIRLWKDKVITQLTGGLGGMAKMRKVTVVNGYGKFTGPNSILVEGADGEQTTVNFDNAIVAAGSRPIKLPFIPHEDPRIWDSTDALELKEVPEKLLVMGGGIIGLEMGTVYHALGSQIDVVEMFDQVIPAADKDIVKIFTKRIEKKFNLMLETKVTAVEAREDGIYVSMEGKKAPAEPVRYDAVLVAIGRVPNGKLLDAEKAGIEVDERGFIHVDKQMRTNVPHIHAIGDIVGQPMLAHKGVHEGHVAAEVISGKKHYFDPKVIPSIAYTEPEVAWVGKTEKEAKAEGINYEVATFPWAASGRAIASDCSDGMTKMIFDKDTHRVIGGAIVGTNGGELLGEIGLAIEMGCDAEDIALTIHAHPTLHESVGLAAEVFEGSVTDLPNAKAVKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVQ5</accession>
    <name>D0YVQ5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ATP-dependent helicase HrpB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001220</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297665.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001220"/>
    <dbReference type="EnsemblBacteria" id="EEZ40198">
        <property type="protein sequence ID" value="EEZ40198"/>
        <property type="gene ID" value="VDA_001220"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1643">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="604268at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010225">
        <property type="entry name" value="HrpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013689">
        <property type="entry name" value="RNA_helicase_ATP-dep_HrpB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04408">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08482">
        <property type="entry name" value="HrpB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005496">
        <property type="entry name" value="ATP_hel_hrpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01970">
        <property type="entry name" value="DEAH_box_HrpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="2">
        <location>
            <begin position="14"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="3">
        <location>
            <begin position="196"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="804"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="804"/>
            <end position="823"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="830" mass="92316" checksum="3AC6A60218021908" modified="2010-01-19" version="1">MAQLPIDAVLADITTALQSGSQLILKAPPGAGKSTQLPLHLLRTAFCSEKCSGKIILLEPRRLAARNIARYLASQLGEEVGQTVGLRMRGENKVSSQTQLEIVTEGVMTKMLQQDPELNGIELLIFDEFHERSIHADTALALALEVQEALRDDLKILLMSATLDQQALQNLLPEAHYIESQGRCYPIEYRYQSLRNIRDLTEQCSKAILQLLRTETGSILVFLPGVGEIKRVEELLQQHDLGANVVIAPLYGQQSLSAQQQAIMPTAQGQRKVVLATNIAETSLTIEGIRLVIDCGLERIAQWDGRSGISRLELVKIAQSSAEQRAGRAGRLEPGICVRLYSEEQLSRQPIVPVPEIQRADLTSLALELAQWGCRDISDLQWLTLPPKSSMQAAYQLLSRLGLCQIDRQLTELGQRLYQLGTDPRHGLMLLQGEQLTEQGYDHGVATAALLVALLENPPKGVNNPDLAFALNLLDEKKLAQGGSYLQRAQQYATKFGHQIKPGQIHLELIAVILAAGYPDRIAKARTQLGRYGLANGQGAMINDDEKLAGNDYLVVADLVRTQQGDSRIFSAVAADIALLEQYLPYLFERKSWLDWDEKKGRLTAEERLYCGQLIVSTKALPEPSADQTAEALLNAVRRKGLSCLPWNEASQNLLVRARNAQHWNLNLTLPDLCDNGLLQGLDQWLAPYLQGINSFKALAKLNLVAALEAYIGWEAMQQLNLWLPTHYQVPTGSNIRLRYELHQPPVLAVKLQEMFGEPTSPSIANGQVRLVLELLSPAQRPLQITQDLAAFWQGSYREVQKEMKGRYPKHPWPDDPASHIPTRKTKRQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVV8</accession>
    <name>D0YVV8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002039</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41007">
        <property type="protein sequence ID" value="EEZ41007"/>
        <property type="gene ID" value="VDA_002039"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="40" mass="4500" checksum="5F185FB1126F5920" modified="2010-01-19" version="1">MTLIPNPKNGWGISKYCPLDMEITQKIAEEFAAEVITFIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVY1</accession>
    <name>D0YVY1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribonuclease 3</fullName>
            <ecNumber evidence="3">3.1.26.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Ribonuclease III</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">VDA_001262</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ribonuclease III family.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.3" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001262"/>
    <dbReference type="EnsemblBacteria" id="EEZ40240">
        <property type="protein sequence ID" value="EEZ40240"/>
        <property type="gene ID" value="VDA_001262"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0571">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004525">
        <property type="term" value="F:ribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00593">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014720">
        <property type="entry name" value="dsRBD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011907">
        <property type="entry name" value="RNase_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000999">
        <property type="entry name" value="RNase_III_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036389">
        <property type="entry name" value="RNase_III_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11207">
        <property type="entry name" value="PTHR11207"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00035">
        <property type="entry name" value="dsrm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14622">
        <property type="entry name" value="Ribonucleas_3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00358">
        <property type="entry name" value="DSRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00535">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69065">
        <property type="entry name" value="SSF69065"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02191">
        <property type="entry name" value="RNaseIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50137">
        <property type="entry name" value="DS_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50142">
        <property type="entry name" value="RNASE_3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RNase III" evidence="12">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="DRBM" evidence="11">
        <location>
            <begin position="108"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ40240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="178" mass="19833" checksum="385B13FCFBE8AA27" modified="2010-01-19" version="1">MSFVIADDLYHRFPNVDEGDMSRMRATLVRGKTLAELGREFELGDHLLLGPGELKSGGFRRDSILADCVEAIIGAIYLDSDIEKVRNIVLDWYQSRLETIQPGVNQKDPKTRLQECLQGRRLPLPAYTVTKVHGEAHNQEFTVQCEVTGLDKPVVGKGGSRRKAEQAAAELALQQLES</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVZ1</accession>
    <name>D0YVZ1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nucleoside triphosphate pyrophosphohydrolase MazG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001270</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001270"/>
    <dbReference type="EnsemblBacteria" id="EEZ40248">
        <property type="protein sequence ID" value="EEZ40248"/>
        <property type="gene ID" value="VDA_001270"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3956">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1099129at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004518">
        <property type="entry name" value="MazG_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011551">
        <property type="entry name" value="NTP_PyrPHydrolase_MazG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30522">
        <property type="entry name" value="PTHR30522"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03819">
        <property type="entry name" value="MazG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00444">
        <property type="entry name" value="mazG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MazG" evidence="2">
        <location>
            <begin position="29"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="MazG" evidence="2">
        <location>
            <begin position="170"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="169"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="265" mass="30690" checksum="881AAC48FE79400C" modified="2010-01-19" version="1">MQSSDIEQLLSIMAKLRDPKDGCPWDIKQSFDSIVPYTLEEAYEVADAIEKQNWLDVKEELGDLLFQVVFYSQMAKEQDLFDFDEVVAGICEKLTRRHPHVFANKQFASEAEVKANWEAEKAKERADKAVDNSILANVPLAMPALTRADKIQKRCAQFGFDWDSLAPVAEKVVEELDEVMDEYQQVTLDQNRIEEEMGDLLFSVVNLSRHLNVNPERALQKANKKFERRFRKVEKNVLEKGMEISNCSLEQLDQEWNIVKKMELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW12</accession>
    <name>D0YW12_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Histidine kinase</fullName>
            <ecNumber evidence="3">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">VDA_001317</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297853.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001317"/>
    <dbReference type="EnsemblBacteria" id="EEZ40292">
        <property type="protein sequence ID" value="EEZ40292"/>
        <property type="gene ID" value="VDA_001317"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3275">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1031920at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010559">
        <property type="entry name" value="Sig_transdc_His_kin_internal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011620">
        <property type="entry name" value="Sig_transdc_His_kinase_LytS_TM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07694">
        <property type="entry name" value="5TM-5TMR_LYT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06580">
        <property type="entry name" value="His_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="10" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="41"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="71"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="138"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="171"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="5TM-5TMR_LYT" evidence="14">
        <location>
            <begin position="25"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="His_kinase" evidence="13">
        <location>
            <begin position="367"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF06580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF07694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEZ40292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="568" mass="62745" checksum="FBE23B2605F4E735" modified="2010-01-19" version="1">MELIFSLLQQLSVYLVIAYLLSKTPLFMPITTISGRLSQRFSCYILFSLFCILGTYFGLNIDDAIANTRAIGAVMGGVLGGPIVGFAVGLTGGLHRYSIGGFTDLACAISTTAEGILGGLVHSYYVRRNHIDQLYRPSIVFGITLIAEVLQMAIILLVAKPFDQALELVNAIALPMVIANSAGAALFMSIIHDRKTIYEKYSAAFSSRALTIAQRTVGIMSKGFNEQSAKKIARIVYEETEVGAVAITDREKILAFIGIGDDHHLPGTPISSIHTLRSINRSELVYADGYDIPYCCSIHDKCKLGSALVIPLLGGNNEVLGTIKLYEPKHKLFSTVNVTLGEGIAKLLSNQILTGRYAQQQALLLQAELRLLQAQVNPHFLFNALNTISSVIRRDPTRARQLILHLSQFFRSNLKQDIEQVTLAEELNHVKAYLEIELARFSDRLNVEIDIPDTLLSLKLPTFTLQPLVENAIKHGTAHLLENGKITIYATETQDYIELVVEDNAGNYQVTHESTGLGMKIVDKRLRNKFGQEFGLIMQCQPQQWTRATIHLPHIIAPLTRNGEQTNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW43</accession>
    <name>D0YW43_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pseudouridine synthase</fullName>
            <ecNumber evidence="3">5.4.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001323</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Responsible for synthesis of pseudouridine from uracil.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a uridine in RNA = a pseudouridine in RNA</text>
            <dbReference type="Rhea" id="RHEA:48348"/>
            <dbReference type="Rhea" id="RHEA-COMP:12068"/>
            <dbReference type="Rhea" id="RHEA-COMP:12069"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pseudouridine synthase RluA family.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297860.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001323"/>
    <dbReference type="EnsemblBacteria" id="EEZ40298">
        <property type="protein sequence ID" value="EEZ40298"/>
        <property type="gene ID" value="VDA_001323"/>
    </dbReference>
    <dbReference type="GeneID" id="57339784"/>
    <dbReference type="eggNOG" id="COG0564">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1714699at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120159">
        <property type="term" value="F:rRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd02869">
        <property type="entry name" value="PseudoU_synth_RluA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006225">
        <property type="entry name" value="PsdUridine_synth_RluC/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006224">
        <property type="entry name" value="PsdUridine_synth_RluC/D_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00005">
        <property type="entry name" value="rluA_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01129">
        <property type="entry name" value="PSI_RLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S4" evidence="4">
        <location>
            <begin position="18"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR606225-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="324" mass="36696" checksum="D2A9DEEB9D6221FC" modified="2010-01-19" version="1">MAQQIELTNTVNDSQLGKRLDQVIAELYPDYSRTRIKDWILAGKVAVDGEIIDKPRIKMMGGEQLVINAEIEDEVRWEAQDIPLDIVYEDDDIIVINKPRDFVVHPGAGTPDGTVLNALLWHCPSLAEVPRAGIVHRLDKDTTGLMVVAKTVQAQTRLVRALQKRNITREYEAIAMGKMTGGGTVEKAIGRHSTKRTCMAVHELGKPAITHYRVAEHFREHTRIVLRLETGRTHQIRVHMSYLTHPLVGDATYGGRPRPPRNASDELIQALRAFDRQALHARMLRLTHPITGELMEWHAPLPNDMVAMIDILRKDKELNDEDDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW88</accession>
    <name>D0YW88_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase</fullName>
            <shortName evidence="6">UDP-N-acetylglucosamine acyltransferase</shortName>
            <ecNumber evidence="6">2.3.1.129</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">lpxA</name>
        <name evidence="8" type="ORF">VDA_001370</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a (3R)-hydroxyacyl-[ACP] + UDP-N-acetyl-alpha-D-glucosamine = a UDP-3-O-[(3R)-3-hydroxyacyl]-N-acetyl-alpha-D-glucosamine + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:67812"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="ChEBI" id="CHEBI:173225"/>
            <dbReference type="EC" id="2.3.1.129"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 1/6.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homotrimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the transferase hexapeptide repeat family. LpxA subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.129" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297942.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001370"/>
    <dbReference type="EnsemblBacteria" id="EEZ40345">
        <property type="protein sequence ID" value="EEZ40345"/>
        <property type="gene ID" value="VDA_001370"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1043">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="971098at2"/>
    <dbReference type="UniPathway" id="UPA00359">
        <property type="reaction ID" value="UER00477"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008780">
        <property type="term" value="F:acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03351">
        <property type="entry name" value="LbH_UDP-GlcNAc_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00387">
        <property type="entry name" value="LpxA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029098">
        <property type="entry name" value="Acetyltransf_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037157">
        <property type="entry name" value="Acetyltransf_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010137">
        <property type="entry name" value="Lipid_A_LpxA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43480">
        <property type="entry name" value="PTHR43480"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13720">
        <property type="entry name" value="Acetyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000456">
        <property type="entry name" value="UDP-GlcNAc_acltr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01852">
        <property type="entry name" value="lipid_A_lpxA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6" id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword evidence="1 6" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="4 6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Acetyltransf_11" evidence="7">
        <location>
            <begin position="180"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ40345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="262" mass="28404" checksum="42BB1D76231DD26D" modified="2010-01-19" version="1">MIHETANIHPTAVIEDGVKIGANVTVGPFTYIATNVEIGDGTEVMSHVVIKGPTVIGKDNRIFPFAIVGEECQDKKFQGEQTRLEIGDRNVIRESVQIHRGTTQDKGVTVIGDDNLLCVGAHIAHDVVVGNNTHIGNNSILGGHVTVDDYAGVMALSAVHPFCRVGAYSYIGGCSAVVQDVPPYVLAQGNHASPFGLNLVGLQRNGFEKKELHALRRAYKEIYRSGKTLAEVKPVLEEMAQEWPSVARFIEILDNSSRGIIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWJ2</accession>
    <name>D0YWJ2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UPF0301 protein VDA_001234</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001234</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the UPF0301 (AlgH) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297695.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001234"/>
    <dbReference type="EnsemblBacteria" id="EEZ40212">
        <property type="protein sequence ID" value="EEZ40212"/>
        <property type="gene ID" value="VDA_001234"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1678">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1736059at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00758">
        <property type="entry name" value="UPF0301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003774">
        <property type="entry name" value="UPF0301"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30327">
        <property type="entry name" value="PTHR30327"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02622">
        <property type="entry name" value="DUF179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00758"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="187" mass="20514" checksum="C863E0A9AF4F92CC" modified="2010-01-19" version="1">MNLTNHFLIAMPSLQQTLFEKTVIYICEHNEDGAMGVIINQSVDVSIAEMFEKIEVEPSYLITQPSKLTAQVLNGGPVSEDRGFVLHSGHHNYTSSILITDQLALTTSLDVLSELGSSQGPQQFLVALGYAGWDAGQLEQELAENSWLTVEADPEIIFNTPLNQRWQHAISKMGFTAAQLSTDVGHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWK3</accession>
    <name>D0YWK3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Hypothetical membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_001494</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0126 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298157.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40468">
        <property type="protein sequence ID" value="EEZ40468"/>
        <property type="gene ID" value="VDA_001494"/>
    </dbReference>
    <dbReference type="GeneID" id="57342451"/>
    <dbReference type="eggNOG" id="COG2860">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1665397at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005115">
        <property type="entry name" value="Gly_transporter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03458">
        <property type="entry name" value="Gly_transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="115"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="174"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="Gly_transporter" evidence="8">
        <location>
            <begin position="5"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="Gly_transporter" evidence="8">
        <location>
            <begin position="91"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ40468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="211" mass="22939" checksum="75AABE79E1FFF0BD" modified="2010-01-19" version="1">MLLSILYIIGITAEAMTGAIAAGKRNMDWFGVMLVASATAIGGGSVRDILLGHYPLGWVAHPQYLVITCLAGLLTTVMAKWVVRFHKLFIILDAIGLIVFSIIGCRVAMNMGLPAIICVVAAVVTGVFGGMLRDLICRRQPMVLHKELYASVSLIAGVIYWAMLHFGIDQDLTIIVTLVVGFTMRMAAVQYSWSLPVFSFEDESERVASSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWN7</accession>
    <name>D0YWN7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Rhamnosyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001523</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298212.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001523"/>
    <dbReference type="EnsemblBacteria" id="EEZ40497">
        <property type="protein sequence ID" value="EEZ40497"/>
        <property type="gene ID" value="VDA_001523"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1216">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="957193at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="260" mass="30242" checksum="CBECFC565F79091F" modified="2010-01-19" version="1">MSVYISVVSHGHSDLINNLGCLQLLSKDFFIILKSNKDGDNFSDLAKEEKVHWLDKDYGLGFGHNNNINYQYCINELGMNNDDLFIVFNPDVFMNVDEIYKLLSLMEKDHIDFSCINLFKDKELSIYDNSIRKFPSLFQFVKSFLGLGNDTVLNKDLITCTTPVDWAAGSFLAFTANRYNQLKGFDESYFMYCEDIDICYRSYKQDVPIYYYPQIKALHYAKHANRKLFSKHMYWHISSVFRFLLTKKGLTKSASTIGKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWQ9</accession>
    <name>D0YWQ9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative threonine efflux protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_001455</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298089.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40429">
        <property type="protein sequence ID" value="EEZ40429"/>
        <property type="gene ID" value="VDA_001455"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1280">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1927576at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001123">
        <property type="entry name" value="LeuE-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30086">
        <property type="entry name" value="PTHR30086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01810">
        <property type="entry name" value="LysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006324">
        <property type="entry name" value="LeuE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="41"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="71"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="117"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="150"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="184"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="204" mass="21603" checksum="1E3EAF7F4297D757" modified="2010-01-19" version="1">MTITIWFSLFFVCLLGAMSPGPSLAVVVKHTLAGGRQHGIVTSWAHACGVGCYAVMTLLGLAVVLKQSPQVFTLITYLGAGYLAYLGINALRSKGGIAAKLQAGKHSSLGEAARDGAMISLLNPKLALFFIALFSQFVSVGNDWSAKATIVLTPLIVDGLWYTLIALVLSHANILDKLKSRAKIIDQLSGVVLILLALRVVITV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWT9</accession>
    <name>D0YWT9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Response regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001484</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298137.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001484"/>
    <dbReference type="EnsemblBacteria" id="EEZ40458">
        <property type="protein sequence ID" value="EEZ40458"/>
        <property type="gene ID" value="VDA_001484"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0784">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="656589at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="9"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="550" mass="63229" checksum="E820328CC2209C18" modified="2010-01-19" version="1">MTLDRSKLKILLIDDQSSSALMLKSLFIKLGFSLVDIASSAEDAIYLARHNKYELLCVDYHLNHKISGVDLVSLLKKKHYLSPACSLLFISGDNSSETILTAMTLNPDGFLVKPLSLNILEQKLSVLLKDKQQRQPIFDALIQHNNELAIQRCKEQMLKYGFSNKLNILLLDLLVGQQLWSSVEIILEHLKHSQQHQLIIYKAKLALHHNEIDQAETLLTQLIEQVPLYGEAYDLLIEIYYQQEQWSSALIWAQKVLKLTPAVSARALVVADLAIKTQDFPLYWQTGKTLVHYLPVWGHEWLAIVKRYSDLFEAYFFTTPNRHQALQHKIVMKALFLLASNRLPEGQTPLLRALGNILLVRLEIEIQTKLKGKRRLLVGLRAYLNQMDKLPDEIILDMLPLLLLFGENYLYQAIIEKLSLLDKEKTTELKSAMDAFAYLEQQLQSARELQLSQPQQALLVYHKLLEQYPVATEVHLGHLECLYQLGYFNNHYAVTSSIKAISAMPLPTVLHTRREYVLNQFNLIAPEFEYESDPLQDHESYVAIPQLEQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWU3</accession>
    <name>D0YWU3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Sialyltransferase 0160</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001535</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298232.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001535"/>
    <dbReference type="EnsemblBacteria" id="EEZ40509">
        <property type="protein sequence ID" value="EEZ40509"/>
        <property type="gene ID" value="VDA_001535"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5033ZQ6">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1796640at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021574">
        <property type="entry name" value="PM0188"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043078">
        <property type="entry name" value="Sialyltransferase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11477">
        <property type="entry name" value="PM0188"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="510" mass="57478" checksum="43E2CE31E8C900C4" modified="2010-01-19" version="1">MKKILTVLSIFILSACNSDNTSLKETVSSNSADVVETETYQLTPIDAPSSFLSHSWEQTCGTPILNESDKQAISFDFVAPELKQDEKYCFTFKGITGDHRYITNTTLTVVAPTLEVYIDHASLPSLQQLIHIIQAKDEYPSNQRFVSWKRVTVDADNANKLNIHTYPLKGNNTSPEMVAAIDEYAQSKNRLNIEFYTNTAHVFNNLPPIIQPLYNNEKVKISHISLYDDGSSEYVSLYQWKDTPNKIETLEGEVSLLANYLAGTSPDAPKGMGNRYNWHKLYDTDYYFLREDYLDVEANLHDLRDYLGSSAKQMPWDEFAKLSDSQQTLFLDIVGFDKEQLQQQYSQSPLPNFIFTGTTTWAGGETKEYYAQQQVNVINNAINETSPYYLGKDYDLFFKGHPAGGVINDIILGSFPDMINIPAKISFEVLMMTDMLPDTVAGIASSLYFTIPADKVNFIVFTSSDTITDREEALKSPLVQVMLTLGIVKEKDVLFWADLPDCSSGVCIDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX36</accession>
    <name>D0YX36_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Putative transport protein VDA_001892</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_001892</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the AAE transporter (TC 2.A.81) family. YidE subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298885.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001892"/>
    <dbReference type="EnsemblBacteria" id="EEZ40860">
        <property type="protein sequence ID" value="EEZ40860"/>
        <property type="gene ID" value="VDA_001892"/>
    </dbReference>
    <dbReference type="GeneID" id="57341987"/>
    <dbReference type="eggNOG" id="COG2985">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1458740at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1450">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01016">
        <property type="entry name" value="YidE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006037">
        <property type="entry name" value="RCK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036721">
        <property type="entry name" value="RCK_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023018">
        <property type="entry name" value="Transpt_YidE_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006512">
        <property type="entry name" value="YidE_YbjL"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06826">
        <property type="entry name" value="Asp-Al_Ex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02080">
        <property type="entry name" value="TrkA_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116726">
        <property type="entry name" value="SSF116726"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01625">
        <property type="entry name" value="YidE_YbjL_dupl"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51202">
        <property type="entry name" value="RCK_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="93"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="162"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="371"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="397"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="437"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="466"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="491"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="530"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="6">
        <location>
            <begin position="191"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="6">
        <location>
            <begin position="279"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="552" mass="58738" checksum="618A36C7870B352B" modified="2010-01-19" version="1">MSDIALSISILALVAVLGLWMGNWRIRGVGLGIGGVLFGGIIVGHYTDAWGIALDAHTLHFIQEFGLILFVYTIGIQVGPGFFASLRSSGLKLNGFAALIVVIGCLVAILLHQFFDVPLPVILGVYSGAVTNTPSLGAGQQILSELGANESMLDLTGMGYAVAYPFGICGILLTMWLVRLLFKVNVDHEADEYDSNNGKKTESLHTINVAVKNPNLNGLTLSQVPALTEGSIVCSRLKRGSQLYIPKPNTRIETNDLLHLVGNPKALDKARLVIGEEVDTSLSTRGTDLRVQRLVVTNEIVLGKKIRDLELKEKYDVVVSRLNRAGVELVPTSQTSLQFGDILNLVGRQEAIEAVSGLVGNAHQKLQQVQMLPVFIGIGLGVLLGSIPLYLPGFPAAIKLGLAGGPLIVALILARIGSIGKLYWFMPPSANLALREIGIVLFLAVVGLKSGGGFVDTLVNGDGLSWMGYGILITFLPLMITAIVARMFGGLNYLTICGMLAGSMTDPPALAFANGLHPTSGAAALSYATVYPLVMCLRIISPQLLALLLWAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX47</accession>
    <name>D0YX47_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hypothetical periplasmic linker protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001841</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298796.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001841"/>
    <dbReference type="EnsemblBacteria" id="EEZ40809">
        <property type="protein sequence ID" value="EEZ40809"/>
        <property type="gene ID" value="VDA_001841"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0845">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1200399at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039562">
        <property type="entry name" value="MFP_biotin_lipoyl_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13533">
        <property type="entry name" value="Biotin_lipoyl_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin_lipoyl_2" evidence="2">
        <location>
            <begin position="61"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="364" mass="39929" checksum="5BCDF17675973725" modified="2010-01-19" version="1">MKKYTAIACGILLALGLQGCEKTSVEERSQIRPVSIATVSLTEQAPQLTFPAVAAAADKSSLSFRISGEVARILVRPSDFVKKGQLLATLEPTDFKIEVDDKQAKYNVINSQYQRSAKLVAKGYLAQSQFDELKAQRSIAKANLDIAKLNLSFTQLRAPFDGVISRVPVEQFESVQIGQQVMNIHSTKMVDIDLQAPDMIYSQNSALEINNSKPDARVILPDGSEYKASLKEFTTEPDPGSGAFLVTLTMPMPKDKFILDGMAVEVKADAQKLNVYRQGEPVVPLSAVFNEDGDSLDMAQKYVWVVSNENTVEKRVVVTDKVVPQGVRLVSGVKPNEKIVVAGGNRLRDGDKVRIVNNENKEAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX56</accession>
    <name>D0YX56_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative transcriptional regulatory protein PhoP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001829</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298781.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001829"/>
    <dbReference type="EnsemblBacteria" id="EEZ40797">
        <property type="protein sequence ID" value="EEZ40797"/>
        <property type="gene ID" value="VDA_001829"/>
    </dbReference>
    <dbReference type="GeneID" id="57342055"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1020672at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="2"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="124"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="124"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="224" mass="25504" checksum="DDF799ACCF1FCBB4" modified="2010-01-19" version="1">MRILIVEDDPILSHHLKSQLSELGNQVQCADTAEEGLFFAQNYPNDIAIVDLGLPDRDGLSLIKDMRSKDLRLPILILTARSNWQDKVTGLEAGADDYLVKPFQKEELVARLSALVRRSAGFVKPEMTAGDIRVDLLAKQVFINEEVLELTAFEYDLLEYLMRHSRQVVSKQRLLDVLYEDQEGDPNTIEVMISRLRKKFTKTGQENPISTIRGQGYIFELQAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX90</accession>
    <name>D0YX90_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GGDEF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001949</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298996.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001949"/>
    <dbReference type="EnsemblBacteria" id="EEZ40917">
        <property type="protein sequence ID" value="EEZ40917"/>
        <property type="gene ID" value="VDA_001949"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3706">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1857502at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040572">
        <property type="entry name" value="TackOD1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18551">
        <property type="entry name" value="TackOD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GGDEF" evidence="1">
        <location>
            <begin position="325"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="442" mass="51422" checksum="550310C63573FC41" modified="2010-01-19" version="1">MNKSLIPLYILGDLCVSDERFNVHNINYIDDIINIKHSIIVVEKDIDETLKKLNDKHLTECLIYTSAKTELSSYLSYGIFSCQQAIADWDIVREKAKLIKNTDNKLLSWLFSYPSRRLTPQLNYHLDTVYTYPILNVFYKQNEIIELESFIKSGLIESDSLIDKIRICNTCHSGHLNYIETCPNCESIDIISQHSLHCFTCGHVNNETEFKKANHLECPKCSTKLKHIGVDYDRPLEMFSCKSCHELFIESETRAKCFSCHSIQDVSSTIAKSIYTYRLTDKGEQYVRAKLDYNLPDLNLSGRVDKEYLLSLLPWLSKLSIRHQYDHIICAIKFNGIDEMNFTYGRDKADNFIYEYIDRLNTILRTTDITCQYENDVILLVFPHTSKNSMNTIMKKISRVTENINIPKISVIVGMWTLSKMAMDKSITRWLEDKIESIENDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXA1</accession>
    <name>D0YXA1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Anaerobic nitric oxide reductase flavorubredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">VDA_001641</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298426.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001641"/>
    <dbReference type="EnsemblBacteria" id="EEZ40614">
        <property type="protein sequence ID" value="EEZ40614"/>
        <property type="gene ID" value="VDA_001641"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0426">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1773">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1149616at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016966">
        <property type="term" value="F:nitric oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00730">
        <property type="entry name" value="rubredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01312">
        <property type="entry name" value="NorV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023957">
        <property type="entry name" value="Anaer_NO_rdtase_flvorubredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024934">
        <property type="entry name" value="Rubredoxin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024935">
        <property type="entry name" value="Rubredoxin_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00301">
        <property type="entry name" value="Rubredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00163">
        <property type="entry name" value="RUBREDOXIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50903">
        <property type="entry name" value="RUBREDOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0288">FMN</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="11">
        <location>
            <begin position="254"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="Rubredoxin-like" evidence="12">
        <location>
            <begin position="442"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ40614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="495" mass="55454" checksum="B21020F64F26D857" modified="2010-01-19" version="1">MAIQVKNNIQWVGQRDWEVRDFHGTEYKTTKGTSYNSYLIREEKTVLIDTVDHKFSHAFLQNLEQEIDLNEIDYVVINHAEEDHAGALSALMARIPGTPIYCTANAIDSIVGHHHHPEWNFNVVKTGDSLDIGNGKSLVFVETPMLHWPDSMMTYMTGDAVLFSNDAFGQHYCDERLFNDEVDQTELMEQCLRYYANILTPFSPLVTAKIHEVLGFNLPVSMVATSHGVIWRENPTQIIEQYLTWANEYKEDKITIFYDSMSNNTRMMADAIAQGITETDPNVSVKIFNVARHDKNEILAHVFGSKGILVGSSTMNNVMMPKVAGMLEEITGLRFKGKKAGAFGSYGWNGGAVDRIHARLTDAGFFTTIGLKTKWRPDGKAIEECREHGRTIAREWALAPLTVKTQPSVTPVTPTKSAPLNIQQATAPSTESKMQCNPQKIGQKMLCTVCQWVYDPEIGEPNQEVAPGTAWEDVPDSFLCPECGIGKDVFEPIND</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXC6</accession>
    <name>D0YXC6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 11 12">Uridine kinase</fullName>
            <ecNumber evidence="7 11 12">2.7.1.48</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Cytidine monophosphokinase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Uridine monophosphokinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">udk</name>
        <name evidence="14" type="ORF">VDA_001666</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>ATP + cytidine = ADP + CMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24674"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17562"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.48"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 11 12">
            <text>ATP + uridine = ADP + H(+) + UMP</text>
            <dbReference type="Rhea" id="RHEA:16825"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16704"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.48"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5 11 12">Pyrimidine metabolism; CTP biosynthesis via salvage pathway; CTP from cytidine: step 1/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 11 12">Pyrimidine metabolism; UMP biosynthesis via salvage pathway; UMP from uridine: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 11 12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6 11 12">Belongs to the uridine kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.48" evidence="7 11 12"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298478.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001666"/>
    <dbReference type="EnsemblBacteria" id="EEZ40639">
        <property type="protein sequence ID" value="EEZ40639"/>
        <property type="gene ID" value="VDA_001666"/>
    </dbReference>
    <dbReference type="GeneID" id="57342252"/>
    <dbReference type="eggNOG" id="COG0572">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1793376at2"/>
    <dbReference type="UniPathway" id="UPA00574">
        <property type="reaction ID" value="UER00637"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00579">
        <property type="reaction ID" value="UER00640"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004849">
        <property type="term" value="F:uridine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044211">
        <property type="term" value="P:CTP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044206">
        <property type="term" value="P:UMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd02023">
        <property type="entry name" value="UMPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00551">
        <property type="entry name" value="Uridine_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006083">
        <property type="entry name" value="PRK/URK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026008">
        <property type="entry name" value="Uridine_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000764">
        <property type="entry name" value="Uridine_kinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00485">
        <property type="entry name" value="PRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00235">
        <property type="entry name" value="udk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11 12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11 12 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="10 11 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 11 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PRK" evidence="13">
        <location>
            <begin position="10"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="15"/>
            <end position="22"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00005408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00021478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEZ40639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="214" mass="24302" checksum="9B4397658AD8DC29" modified="2010-01-19" version="1">MSENSHQCVIIGIAGASASGKSLIASTVYNELKEKVGDHQIGVITEDCYYNDQSHLSMEERVKTNYDHPNALDHDLLCDHLQMLMEGKSVEVPQYSYSEHTRMTETSTMTPKKVIILEGILLLTDPRLRNLMHASVFMDTPLDICLLRRLQRDVAERGRTMESVLVQYQKTVRPMFMQFIEPSKQYADIIVPRGGKNRIAIDVLKAHIAKLLKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXD4</accession>
    <name>D0YXD4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Sodium-type flagellar protein MotY</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001613</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298379.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001613"/>
    <dbReference type="EnsemblBacteria" id="EEZ40586">
        <property type="protein sequence ID" value="EEZ40586"/>
        <property type="gene ID" value="VDA_001613"/>
    </dbReference>
    <dbReference type="GeneID" id="57342309"/>
    <dbReference type="eggNOG" id="COG2885">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="583204at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07185">
        <property type="entry name" value="OmpA_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041544">
        <property type="entry name" value="MotY_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006664">
        <property type="entry name" value="OMP_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006665">
        <property type="entry name" value="OmpA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036737">
        <property type="entry name" value="OmpA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18393">
        <property type="entry name" value="MotY_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00691">
        <property type="entry name" value="OmpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01021">
        <property type="entry name" value="OMPADOMAIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103088">
        <property type="entry name" value="SSF103088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51123">
        <property type="entry name" value="OMPA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0966">Cell projection</keyword>
    <keyword evidence="5" id="KW-0969">Cilium</keyword>
    <keyword evidence="5" id="KW-0282">Flagellum</keyword>
    <keyword evidence="1 2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018654" evidence="3">
        <location>
            <begin position="29"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="OmpA-like" evidence="4">
        <location>
            <begin position="180"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="297" mass="34163" checksum="D81A97F3EAE2533E" modified="2010-01-19" version="1">MAWHQKQLTIISRCLLCCGLFLPLPSFAVTQYLAKPSQSQWQLKTNTQLECQLVHQIPGYGLAQFVSKAGKKINLDFEIDLFRSTGKTANVNLVSMPARWMPGDAAQRMLKLKFFKQFNGYVGGKTAWTMLSELERGRNPTFSYRDWYHSNRYIDVGLSAVAFQKPYQEFNQCLNQLLPYSFDDISFTILHYDNDSEELNELSRKRLMQIADFVRAAKDVDLVLVATYTDSFGTKNENQDLSERRANKLHEYFISLGLPPDRIKVQAFGERREIADNNTPIGRNLNRRVVISLGRSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXG5</accession>
    <name>D0YXG5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA transformation protein TfoX</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298539.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001700"/>
    <dbReference type="EnsemblBacteria" id="EEZ40671">
        <property type="protein sequence ID" value="EEZ40671"/>
        <property type="gene ID" value="VDA_001700"/>
    </dbReference>
    <dbReference type="GeneID" id="57342218"/>
    <dbReference type="eggNOG" id="COG3070">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1803592at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007077">
        <property type="entry name" value="TfoX_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007076">
        <property type="entry name" value="TfoX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026256">
        <property type="entry name" value="TfoX_Sxy"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04994">
        <property type="entry name" value="TfoX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04993">
        <property type="entry name" value="TfoX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028788">
        <property type="entry name" value="TfoX_Sxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TfoX_N" evidence="1">
        <location>
            <begin position="11"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="TfoX_C" evidence="2">
        <location>
            <begin position="115"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="196" mass="22380" checksum="5CC825AD02B4C86D" modified="2010-01-19" version="1">MRNIKDEFLNYLNDFGPFEKRSMFGGTGVFVDGAMYAIINNGRIFLRGGETLDDELIGLNCGRFKHVKRSTTAIVNYYDITTIYLDNEPKCRDLVNKSIQYACAERNIKFSEDSRRLRDLPNMRLTLERMVKKAGIPDVKSFMSLGAVEVYRKVRRSHGSGVDVKLLWIFAGAVDGCHWTLLKDEQKSVLLKALNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXG6</accession>
    <name>D0YXG6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">D-serine dehydratase transcriptional activator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001701</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298541.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001701"/>
    <dbReference type="EnsemblBacteria" id="EEZ40672">
        <property type="protein sequence ID" value="EEZ40672"/>
        <property type="gene ID" value="VDA_001701"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="846433at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="11"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="310" mass="35197" checksum="B1E63B393FE638FF" modified="2010-01-19" version="1">MQLPKLSGSVLSGLHCFLIAADQMSFTRAAETLCLTQSAVSHKIKNLEEILGVKLFIRQPRKLTLTPEGQHLKEVLAHNFGDIALEIRDLKSTELSGELNVSVPPTFAQRWLVPRLKGFLDKYPSVRVHLRTRNDLVDFQTESFDCAIYFGHGKYAGLHAVKLMDETMLPVCSHEYAVEHNLYHHPENLILCLLLHDAAPWARAGRNDEWQYWAKRFGVELPDNGCTFDRADLALQAAERGIGVAMGRRSFITEQLKENRLVTPFDMSVFSPQHYYVVCRQDVKDSARIQAFQSWLMSEIAQTDNDDLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXJ4</accession>
    <name>D0YXJ4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 10">Uridine phosphorylase</fullName>
            <ecNumber evidence="5 10">2.4.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">VDA_001708</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>phosphate + uridine = alpha-D-ribose 1-phosphate + uracil</text>
            <dbReference type="Rhea" id="RHEA:24388"/>
            <dbReference type="ChEBI" id="CHEBI:16704"/>
            <dbReference type="ChEBI" id="CHEBI:17568"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57720"/>
            <dbReference type="EC" id="2.4.2.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Pyrimidine metabolism; UMP biosynthesis via salvage pathway; uracil from uridine (phosphorylase route): step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the PNP/UDP phosphorylase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.3" evidence="5 10"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298552.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001708"/>
    <dbReference type="EnsemblBacteria" id="EEZ40679">
        <property type="protein sequence ID" value="EEZ40679"/>
        <property type="gene ID" value="VDA_001708"/>
    </dbReference>
    <dbReference type="GeneID" id="57342207"/>
    <dbReference type="eggNOG" id="COG2820">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1028277at2"/>
    <dbReference type="UniPathway" id="UPA00574">
        <property type="reaction ID" value="UER00633"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004850">
        <property type="term" value="F:uridine phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009164">
        <property type="term" value="P:nucleoside catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009166">
        <property type="term" value="P:nucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044206">
        <property type="term" value="P:UMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018016">
        <property type="entry name" value="Nucleoside_phosphorylase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000845">
        <property type="entry name" value="Nucleoside_phosphorylase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010058">
        <property type="entry name" value="Uridine_phosphorylase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01048">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="SSF53167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01718">
        <property type="entry name" value="Uridine-psphlse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01232">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PNP_UDP_1" evidence="11">
        <location>
            <begin position="21"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00021980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ40679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="255" mass="27365" checksum="F151C367E5134CDD" modified="2010-01-19" version="1">MSDNKVFHLGVNQADLNGATLAIIPGDPARVEKIANLMDEPEFLASSREYTVYRAKLDGKSVVVCSTGIGGPSTSIAVEELAQLGVRTFLRVGTTGAIQPNINVGDMIVTIGSVRLDGASLHFAPMEFPAVADFDVATAMKNACDDEGLTVHTGVTASSDTFYPGQERYDTFTGRVVRRFQGSMKEWQEMGVLNFEMESATLLTMCASSGLRAGCVAGVIINRTQKEIPDHATLKETEAKSIKVVVDAARRMLAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXJ8</accession>
    <name>D0YXJ8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hypothetical membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001712</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001712"/>
    <dbReference type="EnsemblBacteria" id="EEZ40683">
        <property type="protein sequence ID" value="EEZ40683"/>
        <property type="gene ID" value="VDA_001712"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5032QDR">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011577">
        <property type="entry name" value="Cyt_b561_bac/Ni-Hgenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016174">
        <property type="entry name" value="Di-haem_cyt_TM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01292">
        <property type="entry name" value="Ni_hydr_CYTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81342">
        <property type="entry name" value="SSF81342"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="58"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="127"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="168"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="Ni_hydr_CYTB" evidence="3">
        <location>
            <begin position="19"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="194" mass="22281" checksum="104CE4FCF0F47F52" modified="2010-01-19" version="1">MMSWLHGFYRYIKHYFPNVGLRHLHTTLATLIILQILNSNLIHMTHDGILKEGPFATLFLWFHICIGLLAVFATIGMIVFMLTKQSFRQFFPYLFGDNEVLKDDIKQLMKGKLPEPREKGLGNIIQGLGIGALILIEAAALIWLALWVSHSPYANEFRELHKTFTGLIEVYLVGHGGMALLHFIVERKRFMTND</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXP8</accession>
    <name>D0YXP8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Signal transduction protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001740</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298605.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001740"/>
    <dbReference type="EnsemblBacteria" id="EEZ40708">
        <property type="protein sequence ID" value="EEZ40708"/>
        <property type="gene ID" value="VDA_001740"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2905">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="301791at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008773">
        <property type="term" value="F:[protein-PII] uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018821">
        <property type="entry name" value="DUF294_put_nucleoTrafse_sb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005105">
        <property type="entry name" value="GlnD_Uridyltrans_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03445">
        <property type="entry name" value="DUF294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10335">
        <property type="entry name" value="DUF294_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0129">CBS domain</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="2">
        <location>
            <begin position="17"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="3">
        <location>
            <begin position="156"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="3">
        <location>
            <begin position="229"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="626" mass="71326" checksum="64BF07D4625A2AC7" modified="2010-01-19" version="1">MEVEQIEILNFINQQPPFDLLPEEKQQEIAVEIEIAYYRSGATILNIGDQIHDLYLLRSGAVEIYRRNGELYDRLEEGDVFGQVGLLMNNRVRMPAKALEDTLLYCIPEPIFSALCDEFDNFSEFFEVRDTARLRNTVSTQQDENDLTTSKIKTLLTREAVIIENHCTIQYAAQTMADENISSLLISDPEINPEDDELDPIVGIITDRDLCTRVLAQGLDVNLPVKDVMSTNLITLDHNAYVFEAMLTMLRCNVHHLPVMRNQKALGVLSMSDIVRYESQNSLLLVSSIYQQQTVEELEAISKQVKDCFVRMVNEDANSHMIGSAMAEIGRSFKQRLLELAEDQLGHPPIPYCFLALGSMARDEQLMVTDQDNAIILDNSYDPEKHGQYFSDLAQFVCDGLAACGYSYCEGEIMAINPEWRKTRREWELCFADWIDNPKPQALLNSSIFFDLDGVWGRTKWAKQLNGFIVKKARNNQRFLACLARNALNRTPPLGFFKDFVMEKNGQHNNSINLKRRGTAPLADLIRVHALAAGSRSQNSLERLDDVIEAGILPPGRGPDLRDAMEYISLVRIRHQALDIEAGIEPDNSIEPENMSDFERRNLKDAFQILSKAQNFLKFRYQPTRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXU5</accession>
    <name>D0YXU5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Metal-dependent carboxypeptidase</fullName>
            <ecNumber evidence="1">3.4.17.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_002108</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of a C-terminal amino acid with broad specificity, except for -Pro.</text>
            <dbReference type="EC" id="3.4.17.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="2">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M32 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.17.19" evidence="1"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299457.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41076">
        <property type="protein sequence ID" value="EEZ41076"/>
        <property type="gene ID" value="VDA_002108"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2317">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="239313at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001333">
        <property type="entry name" value="Peptidase_M32_Taq"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34217">
        <property type="entry name" value="PTHR34217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02074">
        <property type="entry name" value="Peptidase_M32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006615">
        <property type="entry name" value="Zn_crbxpep_Taq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00998">
        <property type="entry name" value="CRBOXYPTASET"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="262"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="261"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="265"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="291"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR006615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR006615-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR006615-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="493" mass="56054" checksum="ED1FD85A23B5880E" modified="2010-01-19" version="1">MSYYKKLEQHARKLSRLNHLSAICGWDQAAMMPSGGNTARSEALAELAVMKHDLATAEYLANWYELAEKEELSHDEKVSLNEMKRQWQQYIALPADLVEAQSLAGSQCEHAWRTQRANNDWDGFKANLEKVVELSRKEAAERAKITGTSKYNALVDLYEPGMTTETLDAIFSEVKTWLPELIQKVQANQAQENIQIPQGPFLIEQQKALSIKAMEILNFDFNHGRIDISTHPFCGGVPTDVRITTRYDETDFSSALMGVIHETGHARYEQGLPQTWRDLPVGEARSMGIHESQSLFFEMQLSRSTAFMAWLAPEIQNVFSRADDASLSAENLGKLTTRVKPGFIRVDADEVTYPAHVILRYEIERDLIEGNIEVADIPALWQKKMAQYLGLDTTDNFKDGCMQDIHWTDGSFGYFPSYTLGAMYAAQFMAAIKREMDVDALIEKHDLSPIFNWLETNIWSKASTLSTDELVRQATGESLNPRYFKEHLESRYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXY0</accession>
    <name>D0YXY0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphoglycerate mutase family 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002143</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299533.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002143"/>
    <dbReference type="EnsemblBacteria" id="EEZ41111">
        <property type="protein sequence ID" value="EEZ41111"/>
        <property type="gene ID" value="VDA_002143"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0406">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1122642at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001345">
        <property type="entry name" value="PG/BPGM_mutase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00175">
        <property type="entry name" value="PG_MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="193" mass="21765" checksum="D370F2C2C7306FDF" modified="2010-01-19" version="1">MKKLYLLRHGQTQFNAEKRLQGHCNSALTEKGQQQATAVGCSLAKEIEDTSGWVIYSSPLGRAMETVTIVAKQLGMDPNDIHQDARLMEYNLGDWEQQEIPQLVQQNPTLLDKPDWYLTAPNAETFDQVCTRLAAFLDDSSVPDNIIVVSHGLTGATLRGLYTQMSYPQVWQQDLPQDAYFLLSHQQITRIQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY34</accession>
    <name>D0YY34_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PIN_12 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002197</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299632.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41165">
        <property type="protein sequence ID" value="EEZ41165"/>
        <property type="gene ID" value="VDA_002197"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502ZFAI">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2018616at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032557">
        <property type="entry name" value="DUF4935"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16289">
        <property type="entry name" value="PIN_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PIN_12" evidence="2">
        <location>
            <begin position="4"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="67"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="380" mass="42676" checksum="C1DF444287BED1B1" modified="2010-01-19" version="1">MKNIVLDTNILHKEGLISGRMQVLKKLVDAKLITIFVPDIVLREFSTKRVTEITNALNSIQGSLAKSDKKQDHLTELKKRSAVLENEVVELKKIVEKSVLEDVEHWLGSHQVQVLTFKVENITKVVDDYFTGSGVFKALKSREDFPDSMIHQTIIDLVESVGEVHAVLIDGAFKKGIEKQEGVIVLNSLKALLELDDIAEYLANAPFEEMFTSHGVAEQLQQYFAYQKELISHIYISDEGVHNTELIGINVYNATIDWPSENDIRNLAISNVYSVSDSEFTADISFVTDTTVHYVSDFGSYLQVERNANRNVDMDSMNGDGFCDLYEGFTVELSGKIHFTFSERNNIEEATSLMNSLIENEAQVSIDLEIDSATLLSIIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYG0</accession>
    <name>D0YYG0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hypothetical outer membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002323</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299867.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002323"/>
    <dbReference type="EnsemblBacteria" id="EEZ41291">
        <property type="protein sequence ID" value="EEZ41291"/>
        <property type="gene ID" value="VDA_002323"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3108">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2028958at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010275">
        <property type="entry name" value="DUF882"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009045">
        <property type="entry name" value="Hedgehog_sig/DD-Pept_Zn-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37425">
        <property type="entry name" value="PTHR37425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05951">
        <property type="entry name" value="Peptidase_M15_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55166">
        <property type="entry name" value="SSF55166"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019848" evidence="2">
        <location>
            <begin position="31"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="185" mass="20575" checksum="77C29C2E48F8B9F4" modified="2010-01-19" version="1">MSDIHISRRQLLIAGGLALGACALPGTAIATPFKAKDPRTISLCNIHTGENLETEYYNGRGYIYSELKRMNHLCRDFRQNEATRMDKRLFDTIAHIQDVLGHKGQAQIISGYRSPATNKMLARRSGGVAKKSYHMTGQAIDFNLEGIPLSKVRRVAMELNIGGVGYYPKSGFVHIDTGPVRQWRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYL4</accession>
    <name>D0YYL4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Competence/damage-inducible protein CinA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002377</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299986.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002377"/>
    <dbReference type="EnsemblBacteria" id="EEZ41345">
        <property type="protein sequence ID" value="EEZ41345"/>
        <property type="gene ID" value="VDA_002377"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1058">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1834406at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00885">
        <property type="entry name" value="cinA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.980.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008135">
        <property type="entry name" value="Competence-induced_CinA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036425">
        <property type="entry name" value="MoaB/Mog-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001453">
        <property type="entry name" value="MoaB/Mog_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00994">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00852">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53218">
        <property type="entry name" value="SSF53218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00200">
        <property type="entry name" value="cinA_nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00177">
        <property type="entry name" value="molyb_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MoCF_biosynth" evidence="1">
        <location>
            <begin position="5"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="404" mass="45526" checksum="57E24511878B7ED1" modified="2010-01-19" version="1">MTKIAMISTGEEVLYGDIVDTNASWLSHHLCQLGFTMAYRSTVGDNLESICEEIKRISKLVDVVIVNGGLGPTTDDLSAQAAAKALGVQLELNEAWVEQMHLKFQQMQCDMPKSNLKQAMLPLGAELIDNPVGTACGFCIELNHARVYFTPGVPREFKHMVETQIVPKLQRFYSSAEAKQVERIYTFGLTESGISDVLDHWNLPEGCELGYRSALPFIEIKLFHRNNKTEQITAFKDAIIDKFQANVVSVDQSLLDALSEQLTKKKQTLNVSEVGIMGTLAYQFSQHEGIANLLINSRCSYHLVAPVELSVLVQQLQKEVSEQLEDIGLYIYANNDKSYTLALITHQYQKLIRVKPYRQYNIKNQSILIATLVQIMLLNYLLGNGDIDEYLNFEYLGVFETEID</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYM1</accession>
    <name>D0YYM1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">DNA topoisomerase 1</fullName>
            <ecNumber evidence="10">5.6.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">DNA topoisomerase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">topA</name>
        <name evidence="13" type="ORF">VDA_002384</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>ATP-independent breakage of single-stranded DNA, followed by passage and rejoining.</text>
            <dbReference type="EC" id="5.6.2.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the type IA topoisomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.1" evidence="10"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002384"/>
    <dbReference type="EnsemblBacteria" id="EEZ41352">
        <property type="protein sequence ID" value="EEZ41352"/>
        <property type="gene ID" value="VDA_002384"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0550">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003917">
        <property type="term" value="F:DNA topoisomerase type I (single strand cut, ATP-independent) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00186">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00952">
        <property type="entry name" value="Topoisom_1_prok"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000380">
        <property type="entry name" value="Topo_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003601">
        <property type="entry name" value="Topo_IA_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023406">
        <property type="entry name" value="Topo_IA_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013497">
        <property type="entry name" value="Topo_IA_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013824">
        <property type="entry name" value="Topo_IA_cen_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013825">
        <property type="entry name" value="Topo_IA_cen_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013826">
        <property type="entry name" value="Topo_IA_cen_sub3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023405">
        <property type="entry name" value="Topo_IA_core_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003602">
        <property type="entry name" value="Topo_IA_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013498">
        <property type="entry name" value="Topo_IA_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005733">
        <property type="entry name" value="TopoI_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013263">
        <property type="entry name" value="TopoI_Znr_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028612">
        <property type="entry name" value="Topoisom_1_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42785">
        <property type="entry name" value="PTHR42785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08272">
        <property type="entry name" value="Topo_Zn_Ribbon"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01131">
        <property type="entry name" value="Topoisom_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01751">
        <property type="entry name" value="Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01396">
        <property type="entry name" value="zf-C4_Topoisom"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00417">
        <property type="entry name" value="PRTPISMRASEI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00437">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00436">
        <property type="entry name" value="TOP1Bc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56712">
        <property type="entry name" value="SSF56712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01051">
        <property type="entry name" value="topA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00396">
        <property type="entry name" value="TOPOISOMERASE_I_PROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9 10 13" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0799">Topoisomerase</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Toprim" evidence="12">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with DNA" evidence="10">
        <location>
            <begin position="169"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-tyrosine intermediate" evidence="10">
        <location>
            <position position="296"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="3"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="145"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="149"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="161"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="298"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ41352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="852" mass="95185" checksum="A0B3D4FED4F00E57" modified="2010-01-19" version="1">MGHVRDLPTGARAATGKKAPATSTKGLSAEEKARVKKEKDRNSLIKKMGVDPYHDWAANYEILPGKEKVVSELQKLAEEAEYVYLATDLDREGEAIAWHLREIIGGDDARYKRVVFNEITKNAIQQAFEQPGELNMDGVNAQQARRFLDRVVGFMVSPLLWKKIARGLSAGRVQSVAVKLIVEREREIKAFVPEEFWDIHANTLTAGKDELRLLVAQQAGKAFRPVNETETMAAKALLDKAAYEVIDREDRPTSSKPSAPFITSTLQQAASTRLGYGVKRTMGLAQRLYEAGYITYMRTDSTNLSKEAVEAAREFISGEYGDEYLPGKPNVYGSKENAQEAHEAIRPSSVTVRAEDLDGMEQDAVKLYDLIWRQFVACQMVPAQYDSSTITVRAADFTLKAKGRTLRFAGWTKVQRPSGKNEDMTLPMVSVGDKLELSDVEPKQHFTKPPARFTEAALVKELEKRGIGRPSTYASIISTIQDRGYVRVDQRRFYAEKMGEIVSDRLDDSFPDLMDFDFTARMEGNLDQIAEGEKNWKAVLDNFFSDFTTELEKAELDETEGGMKPNNIVLTDIECPTCSRPMGIRTASTGVFLGCSGYALPPKERCKTTINLGSEDGIVNVLEEDVETAALRAKKRCPKCGTAMDAYLIDQTRKLHVCGNNPSCDGYIVEKGEFKLKGYDGPVIECDKCGSDMELKNGRFGKYMGCTNENCKNTRKILKNGEIAPPKEEPVHLPELPCTQDPDAYFVLRDGASGLFMAASTFPKSRETRAPLVEELVRFKDRLSPKFLYLTDAPVADPDGLPTVVRFARKTKENYVRSEIDGKPSGWTALFVDGKWVITDKRKKPKKEKAEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYN1</accession>
    <name>D0YYN1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Anthranilate phosphoribosyltransferase</fullName>
            <ecNumber evidence="5">2.4.2.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">trpD</name>
        <name evidence="8" type="ORF">VDA_002394</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>diphosphate + N-(5-phospho-beta-D-ribosyl)anthranilate = 5-phospho-alpha-D-ribose 1-diphosphate + anthranilate</text>
            <dbReference type="Rhea" id="RHEA:11768"/>
            <dbReference type="ChEBI" id="CHEBI:16567"/>
            <dbReference type="ChEBI" id="CHEBI:18277"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="EC" id="2.4.2.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="5">Binds 2 magnesium ions per monomer.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 2/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the anthranilate phosphoribosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.18" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300017.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002394"/>
    <dbReference type="EnsemblBacteria" id="EEZ41362">
        <property type="protein sequence ID" value="EEZ41362"/>
        <property type="gene ID" value="VDA_002394"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0547">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1238435at2"/>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00041"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004048">
        <property type="term" value="F:anthranilate phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1030.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00211">
        <property type="entry name" value="TrpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005940">
        <property type="entry name" value="Anthranilate_Pribosyl_Tfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000312">
        <property type="entry name" value="Glycosyl_Trfase_fam3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017459">
        <property type="entry name" value="Glycosyl_Trfase_fam3_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036320">
        <property type="entry name" value="Glycosyl_Trfase_fam3_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035902">
        <property type="entry name" value="Nuc_phospho_transferase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02885">
        <property type="entry name" value="Glycos_trans_3N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00591">
        <property type="entry name" value="Glycos_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47648">
        <property type="entry name" value="SSF47648"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52418">
        <property type="entry name" value="SSF52418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01245">
        <property type="entry name" value="trpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4 5" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="1 5 8" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 5" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="Glycos_trans_3N" evidence="7">
        <location>
            <begin position="5"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_3" evidence="6">
        <location>
            <begin position="74"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphoribosylpyrophosphate binding" evidence="5">
        <location>
            <begin position="84"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphoribosylpyrophosphate binding" evidence="5">
        <location>
            <begin position="91"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphoribosylpyrophosphate binding" evidence="5">
        <location>
            <begin position="109"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>anthranilate</name>
            <dbReference type="ChEBI" id="CHEBI:16567"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>anthranilate</name>
            <dbReference type="ChEBI" id="CHEBI:16567"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="225"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ41362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="335" mass="35593" checksum="6A174DAA4456B0AB" modified="2010-01-19" version="1">MTVHELTNKLLQQESLDQTESYQLFDAIIKGEVEPVVLSAVLTALKIKGETPSEIAGAASALQDNANNFPTPDYDFADIVGTGGDGANTINISTTAAFVASACGVKVAKHGNRGVSSQSGSSDLLDKFGIDLAMTAQEARKALDELGICFLFAPQYHQGVRHAMPVRQSLKTRTIFNLLGPLINPAKPTIELMGVYSPELVLPIAKTIATLGFKRAAVVHGSGLDEVAIHGETLVAEIINGEIKQYTVTPADFGLDTYPLEAIKGGSPEENRTIIQHILTGKGTPAQEAAVAVNVALLLRLFGHEDLKANTEKALTIMKTGVAYHLVEQLAARGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYN3</accession>
    <name>D0YYN3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Tryptophan synthase beta chain</fullName>
            <ecNumber evidence="11">4.2.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">trpB</name>
        <name evidence="13" type="ORF">VDA_002396</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + L-serine = D-glyceraldehyde 3-phosphate + H2O + L-tryptophan</text>
            <dbReference type="Rhea" id="RHEA:10532"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
            <dbReference type="ChEBI" id="CHEBI:58866"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.2.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 11">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 11">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 5/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 11">Tetramer of two alpha and two beta chains.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the TrpB family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.20" evidence="11"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300019.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002396"/>
    <dbReference type="EnsemblBacteria" id="EEZ41364">
        <property type="protein sequence ID" value="EEZ41364"/>
        <property type="gene ID" value="VDA_002396"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0133">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="912282at2"/>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00044"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004834">
        <property type="term" value="F:tryptophan synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06446">
        <property type="entry name" value="Trp-synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00133">
        <property type="entry name" value="Trp_synth_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006653">
        <property type="entry name" value="Trp_synth_b_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006654">
        <property type="entry name" value="Trp_synth_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023026">
        <property type="entry name" value="Trp_synth_beta/beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001413">
        <property type="entry name" value="Trp_syn_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00263">
        <property type="entry name" value="trpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00168">
        <property type="entry name" value="TRP_SYNTHASE_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9 11" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="10 11 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="8 11" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="PALP" evidence="12">
        <location>
            <begin position="51"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="11">
        <location>
            <position position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ41364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="396" mass="42583" checksum="E8E47333BDE4A827" modified="2010-01-19" version="1">MSKLDPYFGEFGGQYVPQILVPALDQLEQAFIDAQQDPEFSQQFIELLKEYAGRPTALTLCQNLTKGSKTKLYLKREDLLHGGAHKTNQVLGQALLAKRMGKAEIIAETGAGQHGVATALACALLGLKCRIYMGAKDVERQSPNVFRMKLMGATVIPVHSGSATLKDACNEAMRDWSASYDKAHYLLGTAAGPHPFPTIVREFQRVIGEETKAQILAKEGRLPDAVIACVGGGSNAIGMFADFIEETSVGLIGVEPAGKGLDTNMHGAPLKHGKLGIFFGMKAPLMQDQYGQVEESYSVSAGLDFPSVGPQHAHLNAIGRAEYGSVTDDEALEAFQLLARNEGIIPALESAHALAYALKLIQENPDKEQLLVVNLSGRGDKDIFTVHDILTAQGAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYQ7</accession>
    <name>D0YYQ7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cytolysin and hemolysin HlyA Pore-forming toxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_002420</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300058.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002420"/>
    <dbReference type="EnsemblBacteria" id="EEZ41388">
        <property type="protein sequence ID" value="EEZ41388"/>
        <property type="gene ID" value="VDA_002420"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502ZBG7">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="429328at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051715">
        <property type="term" value="P:cytolysis in another organism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00161">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022220">
        <property type="entry name" value="Hemolysin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043080">
        <property type="entry name" value="Hemolysin_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044883">
        <property type="entry name" value="Hemolysin_pre-stem_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016183">
        <property type="entry name" value="Leukocidin/Hemolysin_toxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036435">
        <property type="entry name" value="Leukocidin/porin_MspA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12563">
        <property type="entry name" value="Hemolysin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07968">
        <property type="entry name" value="Leukocidin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00458">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="SSF50370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56959">
        <property type="entry name" value="SSF56959"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019885" evidence="2">
        <location>
            <begin position="24"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B-type lectin" evidence="3">
        <location>
            <begin position="480"/>
            <end position="558"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="603" mass="68221" checksum="A6EE2F0BEF50DDC1" modified="2010-01-19" version="1">MKIRKLYSCILLGLSSLSASAIADVDNYSTGADVISILSSVQNPDRIVYVNMKQEEISTYNRILEDIIYNDKQYIFDLSFDNNEEKEKLQKKFKDLMGVKFDSNFIVVTGYKNQLMYTPIADANDRMVSVLDHEARSNDISKYPMALALRSGNATSDQSISLPHVSFYLNVNKEITDQECTFRNSLIWDRGSRSFCKNGNISLIYQVILERSLSFGTNGIATPDAKIVRISLDDNTTGAGIHLNDTLTQKYYWANYQVVSGWAREWSASAIAQDYLFDISTSNKKAQILKTFPRENINSNYNINESSGFTIGVTGGAEVSKDGPKASLQANASYSQSKSLSFNTQDYRVEKNSTSAQNVSFRWAREQYPDSESLLDKWTNPVWSEGYPANLKKVQPLSYASFVPKLDVIYKASPNETGKTQFTIDSSVNIMPLYNRSWFYFYGIGAHQTYYGVDDQPLRRVNKAISFTVDWEHPVFTGGTPVNLQLASFNNKCIDIQNNNKVMTAECDINSKSQSFIYDQYNRYVSATNTKLCLDGESLSELQSCSLKLTQKWLWDGDRLKNSFEDKYLTVDSDTLSLETGLSNKQKLNSSYTRVFDPSTINQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYT3</accession>
    <name>D0YYT3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Probable transcriptional regulatory protein VDA_002446</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_002446</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the TACO1 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300107.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002446"/>
    <dbReference type="EnsemblBacteria" id="EEZ41414">
        <property type="protein sequence ID" value="EEZ41414"/>
        <property type="gene ID" value="VDA_002446"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0217">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1304328at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.980">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00693">
        <property type="entry name" value="Transcrip_reg_TACO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017856">
        <property type="entry name" value="Integrase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002876">
        <property type="entry name" value="Transcrip_reg_TACO1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026564">
        <property type="entry name" value="Transcrip_reg_TACO1-like_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029072">
        <property type="entry name" value="YebC-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12532">
        <property type="entry name" value="PTHR12532"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01709">
        <property type="entry name" value="Transcrip_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75625">
        <property type="entry name" value="SSF75625"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01033">
        <property type="entry name" value="TIGR01033"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 4" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="248" mass="26407" checksum="A4BEEC9A87B2AA1A" modified="2010-01-19" version="1">MAGHSKFANIKHRKAAQDAKRGKIFTKLIREIVVSAKEGGAEVENNPRLRAAIDKALSNNMTRDTINRAVTRGAGGDGEDNMETVIYEGYGPAGTAVMVECMTDNRNRTVSAVRHAFSKAGGNLGTDGSVSYLFDKKGVISYAPGLDEDAVMEAALEAGADDVETNDDGSIDVYTTPKEFGAVKDAMDAAGFEAANAEVTLVPSTKADLDITTAPKLMRLIDVLDDLDDVQEVYHNGDMSDEVAATLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYT7</accession>
    <name>D0YYT7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA U34 carboxymethyltransferase</fullName>
            <ecNumber evidence="3">2.5.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">cmoB</name>
        <name evidence="4" type="ORF">VDA_002450</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>5-hydroxyuridine(34) in tRNA + carboxy-S-adenosyl-L-methionine = 5-carboxymethoxyuridine(34) in tRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:52848"/>
            <dbReference type="Rhea" id="RHEA-COMP:13381"/>
            <dbReference type="Rhea" id="RHEA-COMP:13383"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:134278"/>
            <dbReference type="ChEBI" id="CHEBI:136877"/>
            <dbReference type="ChEBI" id="CHEBI:136879"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.-" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002450"/>
    <dbReference type="EnsemblBacteria" id="EEZ41418">
        <property type="protein sequence ID" value="EEZ41418"/>
        <property type="gene ID" value="VDA_002450"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2227">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016765">
        <property type="term" value="F:transferase activity, transferring alkyl or aryl (other than methyl) groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01590">
        <property type="entry name" value="tRNA_carboxymethyltr_CmoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010017">
        <property type="entry name" value="CmoB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027555">
        <property type="entry name" value="Mo5U34_MeTrfas-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08003">
        <property type="entry name" value="Methyltransf_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00452">
        <property type="entry name" value="TIGR00452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 3" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Carboxy-S-adenosyl-L-methionine binding" evidence="3">
        <location>
            <begin position="153"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Carboxy-S-adenosyl-L-methionine binding" evidence="3">
        <location>
            <begin position="182"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>carboxy-S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:134278"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>carboxy-S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:134278"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>carboxy-S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:134278"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>carboxy-S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:134278"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>carboxy-S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:134278"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>carboxy-S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:134278"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="316"/>
        </location>
        <ligand>
            <name>carboxy-S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:134278"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="325" mass="37857" checksum="29165ECE2FD2A89C" modified="2010-01-19" version="1">MLFSFSEFYRLIAQHETLRPWLNILPQQLTDWENKEHGDMGRWLRALKKLPTEKPDLINIQDEVSVAYQNGIENGERKRIESLLRIMQPWRKGPFNIHDIQIDTEWRSDWKWDRVLPHISPLKNRTVLDVGCNNGYHMWRMLGEGAQLAVGIDPSSLFLIQFEAIKRLMGMDDRAYLLPLGIEQLPELKAFDTVFSMGVLYHRRSPLDHIIQLKNQLRKDGELVLETIVIDGDENDVLVPTDRYAQMHNVYFFPSAKALKVWLEKCGFVDVRIVDQCDTTTDEQRSTDWMTNNSLPDYLDPDDPSKTIEGYPAPKRAILVARNPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYZ3</accession>
    <name>D0YYZ3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002506</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002506"/>
    <dbReference type="EnsemblBacteria" id="EEZ41474">
        <property type="protein sequence ID" value="EEZ41474"/>
        <property type="gene ID" value="VDA_002506"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3782">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015003">
        <property type="entry name" value="DUF1853"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08907">
        <property type="entry name" value="DUF1853"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="286" mass="34009" checksum="24D36728851C9150" modified="2010-01-19" version="1">MYYYYRFLLKIAPICAKILYENEIMSLINNIENSIQKFDTDIRAVMALPSLLSDHVNYVDNQWLKHFFQTAVKPTWSRYGGNRRLGFYYQWLWRQFILAHPQYELIAEEVQIYQDKQTLGAIDFLVREKQTQQIEHWEVAIKFYLQHKAQWLGPNANDQLEKKTARMVSHQLLLTEQSAYQQQWQTQFGQPEVKRLIMQGRLFTSESAQIKAPDINPNCAKGLWCFAEHAPAHLRFFDKSEWLSPPRYQDLKPQSNHNALTHPTQAIDEHNQVWFVMPSYWPNSKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZC3</accession>
    <name>D0YZC3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 13">Phosphoenolpyruvate-protein phosphotransferase</fullName>
            <ecNumber evidence="5 13">2.7.3.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12 13">Phosphotransferase system, enzyme I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">VDA_002636</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>L-histidyl-[protein] + phosphoenolpyruvate = N(pros)-phospho-L-histidyl-[protein] + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:23880"/>
            <dbReference type="Rhea" id="RHEA-COMP:9745"/>
            <dbReference type="Rhea" id="RHEA-COMP:9746"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:29979"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:64837"/>
            <dbReference type="EC" id="2.7.3.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 13 16">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the PEP-utilizing enzyme family.</text>
    </comment>
    <dbReference type="EC" id="2.7.3.9" evidence="5 13"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300559.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002636"/>
    <dbReference type="EnsemblBacteria" id="EEZ41604">
        <property type="protein sequence ID" value="EEZ41604"/>
        <property type="gene ID" value="VDA_002636"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1080">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="467393at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008965">
        <property type="term" value="F:phosphoenolpyruvate-protein phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008279">
        <property type="entry name" value="PEP-util_enz_mobile_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018274">
        <property type="entry name" value="PEP_util_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000121">
        <property type="entry name" value="PEP_util_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023151">
        <property type="entry name" value="PEP_util_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036637">
        <property type="entry name" value="Phosphohistidine_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024692">
        <property type="entry name" value="PTS_EI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006318">
        <property type="entry name" value="PTS_EI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008731">
        <property type="entry name" value="PTS_EIN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036618">
        <property type="entry name" value="PtsI_HPr-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05524">
        <property type="entry name" value="PEP-utilisers_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00391">
        <property type="entry name" value="PEP-utilizers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02896">
        <property type="entry name" value="PEP-utilizers_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000732">
        <property type="entry name" value="PTS_enzyme_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47831">
        <property type="entry name" value="SSF47831"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52009">
        <property type="entry name" value="SSF52009"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01417">
        <property type="entry name" value="PTS_I_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00742">
        <property type="entry name" value="PEP_ENZYMES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00370">
        <property type="entry name" value="PEP_ENZYMES_PHOS_SITE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-0418">Kinase</keyword>
    <keyword evidence="13 16" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11 13 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 13" id="KW-0598">Phosphotransferase system</keyword>
    <keyword evidence="20" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 13" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="13 20" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 13" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PEP-utilisers_N" evidence="19">
        <location>
            <begin position="4"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilizers" evidence="17">
        <location>
            <begin position="152"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilizers_C" evidence="18">
        <location>
            <begin position="251"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="region of interest" description="PEP binding" evidence="15">
        <location>
            <begin position="454"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="14">
        <location>
            <position position="189"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="14">
        <location>
            <position position="502"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="296"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="332"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="431"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="455"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="465"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00016544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00033235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR000732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR000732-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR000732-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR000732-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF02896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF05524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="EEZ41604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="575" mass="63592" checksum="CAD6A0A5DADC9C9B" modified="2010-01-19" version="1">MISGILASPGIAFGKALLLQEEEIVLNKNPISADQIDNEIQRFFDARKKSADQLEVIKEKARITFGEEKEAIFEGHIMLLEDEELEEEIIAFIKDNKASADLAIYSIIEEQATTLESLDDEYLKERASDIRDIGSRFVKNALGINVVNLSAINEEVILVANDLTPSETAQINLEYVLGFITDIGGRTSHTSIMARSLEIPAIVGTNDITARVKNGDMLVLDAINNQIVINPSEEELNKFKAIREAHRAEQEELAKLKDLPAITLDGKQVEVCGNIGTVKDCDGVNRNGGEGVGLYRTEFLFMDRDALPTEEEQYQAYKEVAEAMHGEPVIIRTMDIGGDKDLPYLDLPKEMNPFLGWRAIRISLDRREILRDQFRAILRASAHGKIRIMFPMIISVEEVRTLKAAIEEFKAELTAEGLAFDANIEIGVMVETPAAAAIAHHLAKEVSFFSIGTNDLTQYTLAVDRGNELISHLYNPLSPAVLTVIKQVIDASHKEGKWTGMCGELAGDERATLLLLGMGLDEFSMSAISIPRIKKVIRNANFADVKAMAEQALAMPTAAEIEAHVEKFIAEKTIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZG5</accession>
    <name>D0YZG5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">6,7-dimethyl-8-ribityllumazine synthase</fullName>
            <shortName evidence="7">DMRL synthase</shortName>
            <shortName evidence="7">LS</shortName>
            <shortName evidence="7">Lumazine synthase</shortName>
            <ecNumber evidence="4 7">2.5.1.78</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ribH</name>
        <name evidence="8" type="ORF">VDA_002678</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>(2S)-2-hydroxy-3-oxobutyl phosphate + 5-amino-6-(D-ribitylamino)uracil = 6,7-dimethyl-8-(1-D-ribityl)lumazine + H(+) + 2 H2O + phosphate</text>
            <dbReference type="Rhea" id="RHEA:26152"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15934"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58201"/>
            <dbReference type="ChEBI" id="CHEBI:58830"/>
            <dbReference type="EC" id="2.5.1.78"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Cofactor biosynthesis; riboflavin biosynthesis; riboflavin from 2-hydroxy-3-oxobutyl phosphate and 5-amino-6-(D-ribitylamino)uracil: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the DMRL synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.78" evidence="4 7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300681.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002678"/>
    <dbReference type="EnsemblBacteria" id="EEZ41646">
        <property type="protein sequence ID" value="EEZ41646"/>
        <property type="gene ID" value="VDA_002678"/>
    </dbReference>
    <dbReference type="GeneID" id="57341053"/>
    <dbReference type="eggNOG" id="COG0054">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1680292at2"/>
    <dbReference type="UniPathway" id="UPA00275">
        <property type="reaction ID" value="UER00404"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009349">
        <property type="term" value="C:riboflavin synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000906">
        <property type="term" value="F:6,7-dimethyl-8-ribityllumazine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09209">
        <property type="entry name" value="Lumazine_synthase-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.960">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00178">
        <property type="entry name" value="Lumazine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034964">
        <property type="entry name" value="LS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002180">
        <property type="entry name" value="LS/RS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036467">
        <property type="entry name" value="LS/RS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21058">
        <property type="entry name" value="PTHR21058"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00885">
        <property type="entry name" value="DMRL_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52121">
        <property type="entry name" value="SSF52121"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00114">
        <property type="entry name" value="lumazine-synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0686">Riboflavin biosynthesis</keyword>
    <keyword evidence="6 7 8" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="5-amino-6-(D-ribitylamino)uracil binding" evidence="7">
        <location>
            <begin position="57"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="5-amino-6-(D-ribitylamino)uracil binding" evidence="7">
        <location>
            <begin position="81"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="1-deoxy-L-glycero-tetrulose 4-phosphate binding" evidence="7">
        <location>
            <begin position="86"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="89"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="22"/>
        </location>
        <ligand>
            <name>5-amino-6-(D-ribitylamino)uracil</name>
            <dbReference type="ChEBI" id="CHEBI:15934"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>5-amino-6-(D-ribitylamino)uracil</name>
            <dbReference type="ChEBI" id="CHEBI:15934"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>(2S)-2-hydroxy-3-oxobutyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58830"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ41646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="156" mass="16333" checksum="0B3039E965BDCDA6" modified="2010-01-19" version="1">MKVIEGAIAAPNAKVAIVISRFNSFINESLLSGALDALKRQGQVSDDNITVVRCPGAYELPLVAQQVAKSDRYDAIVALGSVIRGGTPHFDYVAGECNKGLAQVALEYNTPVAFGVLTVDSIEQAIERAGTKAGNKGAEAALSALEMVNVLSQIES</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZH0</accession>
    <name>D0YZH0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Serine hydroxymethyltransferase</fullName>
            <shortName evidence="7">SHMT</shortName>
            <shortName evidence="7">Serine methylase</shortName>
            <ecNumber evidence="7">2.1.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">glyA</name>
        <name evidence="10" type="ORF">VDA_002683</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + glycine + H2O = (6S)-5,6,7,8-tetrahydrofolate + L-serine</text>
            <dbReference type="Rhea" id="RHEA:15481"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="EC" id="2.1.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7 8">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Amino-acid biosynthesis; glycine biosynthesis; glycine from L-serine: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the SHMT family.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.1" evidence="7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300693.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002683"/>
    <dbReference type="EnsemblBacteria" id="EEZ41651">
        <property type="protein sequence ID" value="EEZ41651"/>
        <property type="gene ID" value="VDA_002683"/>
    </dbReference>
    <dbReference type="GeneID" id="57341048"/>
    <dbReference type="eggNOG" id="COG0112">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="861782at2"/>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="UniPathway" id="UPA00288">
        <property type="reaction ID" value="UER01023"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004372">
        <property type="term" value="F:glycine hydroxymethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019264">
        <property type="term" value="P:glycine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00378">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00051">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001085">
        <property type="entry name" value="Ser_HO-MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019798">
        <property type="entry name" value="Ser_HO-MeTrfase_PLP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039429">
        <property type="entry name" value="SHMT-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11680">
        <property type="entry name" value="PTHR11680"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00464">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000412">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00096">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4 7" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="6 7 8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SHMT" evidence="9">
        <location>
            <begin position="9"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="125"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="354"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="235"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="362"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="7 8">
        <location>
            <position position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000412-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ41651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="416" mass="45149" checksum="746D6A0A4F0F9561" modified="2010-01-19" version="1">MLKRDMNIADYDAELYAAIQEETARQEEHIELIASENYTSPRVMEAQGSQLTNKYAEGYPGKRYYGGCEYVDKAEQLAIDRACQLFGAEYANVQPHSGSQANNAVYMALLNAGDTVLGMSLAHGGHLTHGSPVNFSGKLYNIIPYGIDENGQIDYDEVEALALEHNPKMIIGGFSAYSQIVDWERMRKIADKVGAYFFVDMAHVAGLVAAGVYPTPVPHAHVVTTTTHKTLAGPRGGLILSNAGEDIYKKLNSAVFPGGQGGPLMHVIAAKAVAFKEAMEPEFTEYQARVVENAKVMVGEFLERGYKIVSGSTENHLFLVDLIDKGITGKEADAALGAANITVNKNSVPNDPRSPFVTSGIRVGTPSITRRGFTAEDAKQLAGWMCDVLDNIDNPQVIADTKAKVLEICKRLPVYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZU6</accession>
    <name>D0YZU6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Purine nucleoside phosphorylase DeoD-type</fullName>
            <shortName evidence="4">PNP</shortName>
            <ecNumber evidence="4">2.4.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">deoD</name>
        <name evidence="6" type="ORF">VDA_002809</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a purine 2'-deoxy-D-ribonucleoside + phosphate = 2-deoxy-alpha-D-ribose 1-phosphate + a purine nucleobase</text>
            <dbReference type="Rhea" id="RHEA:36431"/>
            <dbReference type="ChEBI" id="CHEBI:26386"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57259"/>
            <dbReference type="ChEBI" id="CHEBI:142361"/>
            <dbReference type="EC" id="2.4.2.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a purine D-ribonucleoside + phosphate = a purine nucleobase + alpha-D-ribose 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:19805"/>
            <dbReference type="ChEBI" id="CHEBI:26386"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57720"/>
            <dbReference type="ChEBI" id="CHEBI:142355"/>
            <dbReference type="EC" id="2.4.2.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homohexamer; trimer of homodimers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the PNP/UDP phosphorylase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.1" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301070.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002809"/>
    <dbReference type="EnsemblBacteria" id="EEZ41777">
        <property type="protein sequence ID" value="EEZ41777"/>
        <property type="gene ID" value="VDA_002809"/>
    </dbReference>
    <dbReference type="GeneID" id="57340912"/>
    <dbReference type="eggNOG" id="COG0813">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1028277at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004731">
        <property type="term" value="F:purine-nucleoside phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009164">
        <property type="term" value="P:nucleoside catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042278">
        <property type="term" value="P:purine nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09006">
        <property type="entry name" value="PNP_EcPNPI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01627">
        <property type="entry name" value="Pur_nucleosid_phosp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004402">
        <property type="entry name" value="DeoD-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018016">
        <property type="entry name" value="Nucleoside_phosphorylase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000845">
        <property type="entry name" value="Nucleoside_phosphorylase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43691:SF2">
        <property type="entry name" value="PTHR43691:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01048">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="SSF53167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00107">
        <property type="entry name" value="deoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01232">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PNP_UDP_1" evidence="5">
        <location>
            <begin position="15"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphate binding" evidence="4">
        <location>
            <begin position="88"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Purine nucleoside binding" evidence="4">
        <location>
            <begin position="180"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Purine nucleoside binding" evidence="4">
        <location>
            <begin position="204"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="205"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="5"/>
        </location>
        <ligand>
            <name>a purine D-ribonucleoside</name>
            <dbReference type="ChEBI" id="CHEBI:142355"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="21"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="25"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="4">
        <location>
            <position position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="241" mass="26258" checksum="59B1AAF4AC500459" modified="2010-01-19" version="1">MATPHINAEMGDFADVVLMPGDPLRAKYIAETFLEDIKEVCNVRNMYGYTGTYKGRRISVMGHGMGIPSCSIYATELVKDFGVKKIIRVGSCGAVRDDVNLRDVVIGMGASTDSKVNRMRFGGHDFAALADYGMVQNAVEAAKAKGIKVRVGNLFSADLFYNPDFDFFKTMDKYGILGVEMEAAGIYGLAAEFGAKALTICTVSDHILKGEATTSEERQLTFNEMMEIALESVLIGDKEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z033</accession>
    <name>D0Z033_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hypothetical DedA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002896</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301290.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002896"/>
    <dbReference type="EnsemblBacteria" id="EEZ41864">
        <property type="protein sequence ID" value="EEZ41864"/>
        <property type="gene ID" value="VDA_002896"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0586">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1928533at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032816">
        <property type="entry name" value="SNARE_assoc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09335">
        <property type="entry name" value="SNARE_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="17"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="178"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="201" mass="22338" checksum="3AEAA88209915752" modified="2010-01-19" version="1">MSIEHIITELTPLLQQYGYFVLALAVAIEGMGIPAPGQSLLIVASLLAASGKMSLPVVLLVGWMSSFIGNTLGYVIGRQFGHILVHKQWIKPNTLEKLHQFIDKYGVLGLLISRFVEGIKQFMCLGCGIAQMPARLFFLGNFIAVTVWVLVFGVAPAYLRDEMGSILAFYHKYQTQCWVAVAAILVSIFTLIVLYRRRSMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z072</accession>
    <name>D0Z072_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative esterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002935</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301385.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002935"/>
    <dbReference type="ESTHER" id="lisda-d0z072">
        <property type="family name" value="abh_upf00227"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41903">
        <property type="protein sequence ID" value="EEZ41903"/>
        <property type="gene ID" value="VDA_002935"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3150">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="721431at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008886">
        <property type="entry name" value="UPF0227/Esterase_YqiA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35602">
        <property type="entry name" value="PTHR35602"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05728">
        <property type="entry name" value="UPF0227"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="192" mass="22159" checksum="18611F1EC41DEDB9" modified="2010-01-19" version="1">MKPLLLYIHGFNSSPQSMKAEIMANYCRECRPDIKVVVPRLPSYPQQAAEYIDELVQTYLPDYKLGLVGSSLGGYIATWLSQRYLLPAVVVNPAVKPYELLVDYLGPQQNPYTQEQYVLAPHHMDELKAMDVNNIVHPELIWLLQQEGDEVLDYRQAVEKYTLCRQLIEKQGDHSFVQFERFPAEIIQFLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z074</accession>
    <name>D0Z074_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ADP-ribose pyrophosphatase</fullName>
            <ecNumber evidence="4">3.6.1.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">ADP-ribose diphosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">ADP-ribose phosphohydrolase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Adenosine diphosphoribose pyrophosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">VDA_002937</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ADP-D-ribose + H2O = AMP + D-ribose 5-phosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:10412"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57967"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="3.6.1.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Nudix hydrolase family. NudF subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.13" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301387.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002937"/>
    <dbReference type="EnsemblBacteria" id="EEZ41905">
        <property type="protein sequence ID" value="EEZ41905"/>
        <property type="gene ID" value="VDA_002937"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0494">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1831818at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047631">
        <property type="term" value="F:ADP-ribose diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004385">
        <property type="entry name" value="NDP_pyrophosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00052">
        <property type="entry name" value="TIGR00052"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="11">
        <location>
            <begin position="58"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013297"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00033056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ41905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="211" mass="23749" checksum="22077C9F872D51AA" modified="2010-01-19" version="1">MCDSMKKQSDIHLFGHNDVEVLNSDTLYQGFFKMVKYRFRHRLFAGGWSLPIEREMFERGHAAALLPYDPKTDQVVLIEQFRVGAMAAGCQPWQLEIVAGIIESNESPEDVVVREAVEEAGVDVSDLRKVTRYLSSSGGCSEMLDIFVGTVDSQTASGLHGLEEEGEDIRVHVVSRNQAYQWVESGKIENAASIIALQWLQLNYQQLQLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0B9</accession>
    <name>D0Z0B9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002982</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301458.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002982"/>
    <dbReference type="EnsemblBacteria" id="EEZ41950">
        <property type="protein sequence ID" value="EEZ41950"/>
        <property type="gene ID" value="VDA_002982"/>
    </dbReference>
    <dbReference type="GeneID" id="57340706"/>
    <dbReference type="eggNOG" id="COG0697">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1515911at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="154"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="186"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="216"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="246"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="280"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="6"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="157"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="306" mass="33657" checksum="1EFCAB26FD05A481" modified="2010-01-19" version="1">MSGPVIGALLALTTAVFWGALPIAMKQAVEVMSPFTIVWYRFITAFIGLGIWLLWRKQLPAKSSLNFPRFGFLLLASLGLAGNFVLFNSALQYLSPPVVQVIIQLAPVILLLSSVWLFKETLGRHQIIGVICLFSGLLLFFNERLVELFTSLSGYTLGVILAVTAALVWVVYGLTQKRLLRDFSSAQILFMVYGICALLLTPFAEPKQLLLMDSRQLGMLMFCCINTLVGYGAFAEALARWQAAQVSAVITLAPLFTILFVDLASLVWPKFVAPVALNSWGYLGAMVVVSGAMFCAIGHKLIRQQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0C0</accession>
    <name>D0Z0C0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L27</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpmA</name>
        <name evidence="7" type="ORF">VDA_002983</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the bacterial ribosomal protein bL27 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301460.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002983"/>
    <dbReference type="EnsemblBacteria" id="EEZ41951">
        <property type="protein sequence ID" value="EEZ41951"/>
        <property type="gene ID" value="VDA_002983"/>
    </dbReference>
    <dbReference type="GeneID" id="57340705"/>
    <dbReference type="eggNOG" id="COG0211">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1904463at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00539">
        <property type="entry name" value="Ribosomal_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001684">
        <property type="entry name" value="Ribosomal_L27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018261">
        <property type="entry name" value="Ribosomal_L27_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15893">
        <property type="entry name" value="PTHR15893"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01016">
        <property type="entry name" value="Ribosomal_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00063">
        <property type="entry name" value="RIBOSOMALL27"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00062">
        <property type="entry name" value="L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00831">
        <property type="entry name" value="RIBOSOMAL_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="8"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="85" mass="9166" checksum="B1742A16B4014677" modified="2010-01-19" version="1">MAHKKAGGSTRNGRDSESKRLGVKRFGGESVLAGNIIVRQRGTKFHAGTNVGLGKDHTLFALSDGKVKFEVKGPKNRKFVSIEAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0I9</accession>
    <name>D0Z0I9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">L-lysine 2,3-aminomutase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">EF-P post-translational modification enzyme B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">VDA_003053</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-lysine = D-beta-lysine</text>
            <dbReference type="Rhea" id="RHEA:44148"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:84138"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 13">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the radical SAM superfamily. KamA family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301701.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003053"/>
    <dbReference type="EnsemblBacteria" id="EEZ42020">
        <property type="protein sequence ID" value="EEZ42020"/>
        <property type="gene ID" value="VDA_003053"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1509">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="557227at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022462">
        <property type="entry name" value="EpmB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003739">
        <property type="entry name" value="Lys_aminomutase/Glu_NH3_mut"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30538">
        <property type="entry name" value="PTHR30538"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004911">
        <property type="entry name" value="DUF160"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00314">
        <property type="entry name" value="L-lysine_2_3-aminomutase_(yjeK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01070">
        <property type="entry name" value="PLP-dependent"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03821">
        <property type="entry name" value="EFP_modif_epmB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00238">
        <property type="entry name" value="TIGR00238"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="10 12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="15" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="14">
        <location>
            <begin position="106"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="13">
        <location>
            <position position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR004911-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR603739-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEZ42020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="340" mass="38433" checksum="3EC4D60376F7D9E9" modified="2010-01-19" version="1">MSHIITRNAPSVEQNWLNDLGNAISDPLKLLNLLKIDPTPWEKGLAARKLFALRVPMSFVERMEVGNPYDPLLRQVLPLEQEFEVHAGYSTDPLEEQDNDIPGLLHKYKNRVLMIVKGGCAINCRYCFRRHFPYQDNKGSKSVWQQSLDYIANHPELDEVILSGGDPLMAKDHELAWLMDGIEQIPHIKRLRIHSRLPVVLPSRVTPDLCQRFASSRLQVILVTHINHCNEINAELTLAMQNLKHANVTLLNQGVLLKGVNDSVQALINLSNRLFDAGILPYYLHVLDKVQGAAHFFVDDIQAKTLMAGLMENVSGYLVPQLTREIGGRSSKTPLDLHLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0V0</accession>
    <name>D0Z0V0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_003164</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ42131">
        <property type="protein sequence ID" value="EEZ42131"/>
        <property type="gene ID" value="VDA_003164"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ42131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="62" mass="6826" checksum="A111FBC09EB3D683" modified="2010-01-19" version="1">METLAAAQAEPELEVQEQECVVTKAKKLKKLAKKKAKLLKKTAKAVKKYEKALAKAKLSMGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0V8</accession>
    <name>D0Z0V8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Universal stress protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_003172</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the universal stress protein A family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302069.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003172"/>
    <dbReference type="EnsemblBacteria" id="EEZ42139">
        <property type="protein sequence ID" value="EEZ42139"/>
        <property type="gene ID" value="VDA_003172"/>
    </dbReference>
    <dbReference type="GeneID" id="57340594"/>
    <dbReference type="eggNOG" id="COG0589">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2040681at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006276">
        <property type="entry name" value="UspA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="3">
        <location>
            <begin position="3"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR006276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ42139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="140" mass="15405" checksum="6F3F56664D023FC6" modified="2010-01-19" version="1">MAYKHILVAVDLSEESFVLLKKAADLAKALDAQLSLIHIDVNYAELYTGLIDINLSDTQDRAANDAQQQLQVLAEKAGYPVAHTLVGSGDLSDEICNAIKDLHVELVVCGHHQDFWSKILSSTKQLLNRTPVDLLMVPLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0Z1</accession>
    <name>D0Z0Z1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Trk system potassium uptake protein TrkA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_003205</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302158.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003205"/>
    <dbReference type="EnsemblBacteria" id="EEZ42172">
        <property type="protein sequence ID" value="EEZ42172"/>
        <property type="gene ID" value="VDA_003205"/>
    </dbReference>
    <dbReference type="GeneID" id="57340385"/>
    <dbReference type="eggNOG" id="COG0569">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1768241at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015079">
        <property type="term" value="F:potassium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1450">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006036">
        <property type="entry name" value="K_uptake_TrkA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006037">
        <property type="entry name" value="RCK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036721">
        <property type="entry name" value="RCK_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003148">
        <property type="entry name" value="RCK_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02080">
        <property type="entry name" value="TrkA_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02254">
        <property type="entry name" value="TrkA_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00335">
        <property type="entry name" value="KUPTAKETRKA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116726">
        <property type="entry name" value="SSF116726"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51202">
        <property type="entry name" value="RCK_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51201">
        <property type="entry name" value="RCK_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="3" id="KW-0630">Potassium</keyword>
    <keyword evidence="2" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="RCK N-terminal" evidence="6">
        <location>
            <begin position="2"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="7">
        <location>
            <begin position="143"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="RCK N-terminal" evidence="6">
        <location>
            <begin position="234"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="7">
        <location>
            <begin position="368"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00017378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ42172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="458" mass="50217" checksum="7FCB028D6A91C5E2" modified="2010-01-19" version="1">MKIIILGAGQVGGTLAENLVGENNDITIVDKDPERLRELQDKFDLRVVQGFASHPRTLREAGAQDADMLVAVTNSDETNMIACQIAFSLFNTPNRVARIRSPEYIKEKEQLFQSDAVPVDHLIAPEELVTGYIERLIEYPGALQVVGFAEDKVGLVAVKAYYGGPLVGNALSALREHMPHVDTRVAAIFRQGRPIRPQGTTIIEADDEVFFVAASNHIRSVMSELQRLEKPYKRIMIVGGGNIGAGLARRLEQSYSVKLIERNPDRAENLSEILQKTIVFCGDASDQELLSEEHIEQIDVFIAVTNDDEANIMSAMLAKRMGAKKVMVLIQRGAYVDLVQGGTIDIAISPQQATISALLTHVRKADIVNVSSLRRGAAEAIEAIAHGDASTSKVVGRAVGDIKLPPGTTIGAIVRGEEVLIAHDRTVIEQDDHVVMFLVDKKYIPDVERLFQPSPFFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z114</accession>
    <name>D0Z114_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Bifunctional protein GlmU</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="15">UDP-N-acetylglucosamine pyrophosphorylase</fullName>
                <ecNumber evidence="15">2.7.7.23</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="15">N-acetylglucosamine-1-phosphate uridyltransferase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="15">Glucosamine-1-phosphate N-acetyltransferase</fullName>
                <ecNumber evidence="15">2.3.1.157</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="15" type="primary">glmU</name>
        <name evidence="17" type="ORF">VDA_003228</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>H(+) + N-acetyl-alpha-D-glucosamine 1-phosphate + UTP = diphosphate + UDP-N-acetyl-alpha-D-glucosamine</text>
            <dbReference type="Rhea" id="RHEA:13509"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:57776"/>
            <dbReference type="EC" id="2.7.7.23"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>acetyl-CoA + alpha-D-glucosamine 1-phosphate = CoA + H(+) + N-acetyl-alpha-D-glucosamine 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:13725"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57776"/>
            <dbReference type="ChEBI" id="CHEBI:58516"/>
            <dbReference type="EC" id="2.3.1.157"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="15">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="15">Bacterial outer membrane biogenesis; LPS lipid A biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="15">Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; N-acetyl-alpha-D-glucosamine 1-phosphate from alpha-D-glucosamine 6-phosphate (route II): step 2/2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="15">Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; UDP-N-acetyl-alpha-D-glucosamine from N-acetyl-alpha-D-glucosamine 1-phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Homotrimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 15">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">In the C-terminal section; belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.23" evidence="15"/>
    <dbReference type="EC" id="2.3.1.157" evidence="15"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003228"/>
    <dbReference type="EnsemblBacteria" id="EEZ42195">
        <property type="protein sequence ID" value="EEZ42195"/>
        <property type="gene ID" value="VDA_003228"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00113">
        <property type="reaction ID" value="UER00532"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00973"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019134">
        <property type="term" value="F:glucosamine-1-phosphate N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003977">
        <property type="term" value="F:UDP-N-acetylglucosamine diphosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000902">
        <property type="term" value="P:cell morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006048">
        <property type="term" value="P:UDP-N-acetylglucosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd03353">
        <property type="entry name" value="LbH_GlmU_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01631">
        <property type="entry name" value="GlmU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005882">
        <property type="entry name" value="Bifunctional_GlmU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038009">
        <property type="entry name" value="GlmU_C_LbH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025877">
        <property type="entry name" value="MobA-like_NTP_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12804">
        <property type="entry name" value="NTP_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01173">
        <property type="entry name" value="glmU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13 15 17" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="10 15" id="KW-0133">Cell shape</keyword>
    <keyword evidence="14 15" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="4 15" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 15" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 15" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="6 15 17" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11 15" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 15" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 15 17" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transf_3" evidence="16">
        <location>
            <begin position="4"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyrophosphorylase" evidence="15">
        <location>
            <begin position="1"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="UDP-GlcNAc binding" evidence="15">
        <location>
            <begin position="20"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="UDP-GlcNAc binding" evidence="15">
        <location>
            <begin position="42"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Linker" evidence="15">
        <location>
            <begin position="169"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-acetyltransferase" evidence="15">
        <location>
            <begin position="190"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Acetyl-CoA binding" evidence="15">
        <location>
            <begin position="325"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="15">
        <location>
            <position position="302"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="166"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="272"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="290"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="305"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="316"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="319"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="344"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="362"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="379"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF12804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EEZ42195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="394" mass="42402" checksum="1D9E838BB45DEB00" modified="2010-01-19" version="1">MKQVLSQEQVEWVLQAEQLGTGHAVNQATPNLADDEQVLILYGDVPLISQTTLENLLDAQPAGGIALLTVVLDDPTGYGRIVRRNGPVVAIVEQKDATEEQKLIKEINTGVMVVSGGDLKRWLSALKNDNAQGEYYLTDIIAAAHEEGRAVEAVHPEKAIEVEGVNNRIQLARLERAFQAMQAERLLEQGVMLRDPARFDLRGDLQCGTDVEIDVNVIIEGSVSLGNNVVIGAGCVLKDCEIDDNTEIRPYSVIEGATVGEDCSVGPFTRLRPGAELMRDAHVGNFVEMKQARLGEGSKAGHLTYLGDAEIGANVNIGAGTITCNYDGANKFKTEIADDVFVGSDTQLIAPVKVGKGATIGAGSTINKDVNDGELVITRAPMRNIQGWKRPVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z123</accession>
    <name>D0Z123_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Probable chromosome-partitioning protein ParB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_003237</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ParB family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302253.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003237"/>
    <dbReference type="EnsemblBacteria" id="EEZ42204">
        <property type="protein sequence ID" value="EEZ42204"/>
        <property type="gene ID" value="VDA_003237"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1475">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="653368at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041468">
        <property type="entry name" value="HTH_ParB/Spo0J"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004437">
        <property type="entry name" value="ParB/RepB/Spo0J"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003115">
        <property type="entry name" value="ParB/Sulfiredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036086">
        <property type="entry name" value="ParB/Sulfiredoxin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17762">
        <property type="entry name" value="HTH_ParB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02195">
        <property type="entry name" value="ParBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00470">
        <property type="entry name" value="ParB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110849">
        <property type="entry name" value="SSF110849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00180">
        <property type="entry name" value="parB_part"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ParB" evidence="5">
        <location>
            <begin position="40"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ42204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="293" mass="32325" checksum="4C9FCD4CC6DCAC8A" modified="2010-01-19" version="1">MSKRGLGKGLDALFATSSVALAKQQAANQAQTLSNDGALRELAVSQLQSGKYQPRKDMADEALAELTESIRAQGIIQPIIVRELTNTHFEIIAGERRWRAARQAGLKQVPCIVKSVDDRATMAIALIENIQREDLNVMEEAQALERLQSEFSLTHQQLAQAVGKSRTAVSNLLRLNQLATEVKHLVETKQIEMGHARALLALPIEQQLAIAQIVVSKALTVRETEALVKKQLEPQVEAKKVTRNPVVEAIENRLSEQFGTPVAISKQKNGKGKIVISFDQDHELQQILDKIGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z190</accession>
    <name>D0Z190_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Cell division ATP-binding protein FtsE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ftsE</name>
        <name evidence="9" type="ORF">VDA_003304</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer. Forms a membrane-associated complex with FtsX.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell inner membrane</location>
            <topology evidence="7">Peripheral membrane protein</topology>
            <orientation evidence="7">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the ABC transporter superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302446.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003304"/>
    <dbReference type="EnsemblBacteria" id="EEZ42271">
        <property type="protein sequence ID" value="EEZ42271"/>
        <property type="gene ID" value="VDA_003304"/>
    </dbReference>
    <dbReference type="GeneID" id="57340256"/>
    <dbReference type="eggNOG" id="COG2884">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1181903at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005286">
        <property type="entry name" value="Cell_div_FtsE_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02673">
        <property type="entry name" value="FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7 9" id="KW-0132">Cell division</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="2"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="35"/>
            <end position="42"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ42271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="223" mass="25012" checksum="6FAC607E3EE63680" modified="2010-01-19" version="1">MIQFQQVSKAYRGGRQALQRVNFHLGRGEMSFLTGHSGAGKSTLLKLICAIERPSDGKILFNDHDISRIPNKQIPFLRRNIGIIFQDHKLLMDRSVYENVALPLRVELASEHEIKRRVSAALDKVGLLDKAKCTPIQLSGGEQQRVGIARAVVNKPMLLLADEPTGNLDADLSQQVMRLFEEFNRVGVSVLMATHDTSLLASHDYRRLDLLQGHLREIVRGAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z193</accession>
    <name>D0Z193_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thiosulfate sulfurtransferase GlpE</fullName>
            <ecNumber evidence="2">2.8.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003307</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.8.1.1" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003307"/>
    <dbReference type="EnsemblBacteria" id="EEZ42274">
        <property type="protein sequence ID" value="EEZ42274"/>
        <property type="gene ID" value="VDA_003307"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0607">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004792">
        <property type="term" value="F:thiosulfate sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="4"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="56" mass="6320" checksum="CAB93961CE05A3DF" modified="2010-01-19" version="1">MDEVDFEQPVIVMCYHGISSQGAAQYLLHQGFEQVYSLEGGFEAWRRAQLPMALGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1C5</accession>
    <name>D0Z1C5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribonuclease PH</fullName>
            <shortName evidence="4">RNase PH</shortName>
            <ecNumber evidence="4">2.7.7.56</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">tRNA nucleotidyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rph</name>
        <name evidence="7" type="ORF">VDA_003339</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>phosphate + tRNA(n+1) = a ribonucleoside 5'-diphosphate + tRNA(n)</text>
            <dbReference type="Rhea" id="RHEA:10628"/>
            <dbReference type="Rhea" id="RHEA-COMP:17343"/>
            <dbReference type="Rhea" id="RHEA-COMP:17344"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:173114"/>
            <dbReference type="EC" id="2.7.7.56"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homohexameric ring arranged as a trimer of dimers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RNase PH family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.56" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302522.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003339"/>
    <dbReference type="EnsemblBacteria" id="EEZ42306">
        <property type="protein sequence ID" value="EEZ42306"/>
        <property type="gene ID" value="VDA_003339"/>
    </dbReference>
    <dbReference type="GeneID" id="57340216"/>
    <dbReference type="eggNOG" id="COG0689">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1824064at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-exoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009022">
        <property type="term" value="F:tRNA nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016075">
        <property type="term" value="P:rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd11362">
        <property type="entry name" value="RNase_PH_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00564">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015847">
        <property type="entry name" value="ExoRNase_PH_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002381">
        <property type="entry name" value="RNase_PH_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018336">
        <property type="entry name" value="RNase_PH_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03725">
        <property type="entry name" value="RNase_PH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="SSF55666"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01966">
        <property type="entry name" value="RNasePH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01277">
        <property type="entry name" value="RIBONUCLEASE_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 4" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 4" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="2 4" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="RNase_PH" evidence="5">
        <location>
            <begin position="10"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="RNase_PH_C" evidence="6">
        <location>
            <begin position="158"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphate (substrate) binding" evidence="4">
        <location>
            <begin position="124"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <note>substrate</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ42306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="238" mass="25792" checksum="D504EBC648BF1E0F" modified="2010-01-19" version="1">MRPSGRSASQVRPITITRQFTAHAEGSVLVEFGNTKVICTASVEENVPRWLKGQGKGWVTAEYGMLPRATHSRNRREAASGKQGGRTMEIQRLIARSLRAAVDLEVLGEQMITVDCDVIQADGGTRTASITGAMVALVDAIHYMLEKGMIKKNPLKTMVAAVSVGIYNGEPICDLEYLEDSAAETDMNVVMTEEGKMIEIQGTAEGEAFSHEELLAMLALAKEGINEIIAQQKQALAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1E4</accession>
    <name>D0Z1E4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Capsular polysaccharide biosynthesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_003358</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302565.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003358"/>
    <dbReference type="EnsemblBacteria" id="EEZ42325">
        <property type="protein sequence ID" value="EEZ42325"/>
        <property type="gene ID" value="VDA_003358"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1208">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="809743at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ42325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="530" mass="60828" checksum="6660AAA839FFD321" modified="2010-01-19" version="1">MFLIMSAAYITSELESEFGTIPPSFLPLGNRRLFQHQIKLAPKGANVYLSIPETYRVSEYDTNWLKINNVNLLRIPEGLSLGASLMSALALSDLASETPLHILFGDTLLTELPSGNDLVTISQVENSYDWAMVTHDHSYWLNTAEDREQLNSNNVVCGYFKFNQPRHLVKALTMAHWDFIQSLNYYHEKHQLNAVETQEWLDFGHLNTYYSSKAKFTTQRAFNQLKINDKWIQKSSVKNNKIAAEANWFATVPAPLRIYLPQYLGSSEVGNTLSYRLEYLYNTALNELYVFSDLPELVWQRILTSCLEFIDECRMHQAVDDSHTNQLQDLFGNKTHQRLNEYCQSIQVQLNTPWTYNGNLSASFSDLLAKSEQYLPTENQLGTVMHGDFCFSNILYDFRSNKVKTIDPRGIDLQGNLTIFGDTRYDLAKLSHSILGLYDWIIAGYYQVDIDYTNHHIQFDIQPSGGIAAIQTLFIEMIAERYQLSANALYAMQIQLFLSMLPLHADDPKRQQALMANAFRLYLLIKDSTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1M2</accession>
    <name>D0Z1M2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8">Elongation factor G</fullName>
            <shortName evidence="8">EF-G</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">fusA</name>
        <name evidence="10" type="ORF">VDA_003436</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302779.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003436"/>
    <dbReference type="EnsemblBacteria" id="EEZ42403">
        <property type="protein sequence ID" value="EEZ42403"/>
        <property type="gene ID" value="VDA_003436"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0480">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="88967at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16262">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01434">
        <property type="entry name" value="EFG_mtEFG1_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03713">
        <property type="entry name" value="EFG_mtEFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00054_B">
        <property type="entry name" value="EF_G_EF_2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009022">
        <property type="entry name" value="EFG_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035649">
        <property type="entry name" value="EFG_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004540">
        <property type="entry name" value="Transl_elong_EFG/EF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005517">
        <property type="entry name" value="Transl_elong_EFG/EF2_IV"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03764">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00889">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00484">
        <property type="entry name" value="EF-G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 8 10" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="6 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="9">
        <location>
            <begin position="8"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="17"/>
            <end position="24"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="88"/>
            <end position="92"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="142"/>
            <end position="145"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ42403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="701" mass="77631" checksum="8EE95C62FCBBEFAD" modified="2010-01-19" version="1">MARKTPIERYRNIGICAHVDAGKTTTTERILFYTGISHKIGEVHDGAATMDWMEQEQERGITITSAATTTFWRGMDSQFDEHRINIIDTPGHVDFTIEVERSLRVLDGAVVVFCGSSGVEPQSETVWRQADRYEVPRMVFVNKMDRTGADFIRVIEQIKTRLGANPVPIQLNIGSEDEFKGVIDLIKMKAINWSEADQGTSFTYEDISADMQELAEEWRMNLVESAAEANDELMDKYLEEGELSEEEIKAGLRQRTLNNEIVVATCGSAFKNKGVQAVLDAVIDFLPSPTEVKAITGEDENGNPVERHSDDKEPFAALAFKIATDPFVGTLTFMRVYSGVVNSGDTVFNTIKEKRERLGRIVQMHANKREEIKEVRAGDIAAAIGLKFATTGDTLCDQNHKVILERMDFPEPVIQIVVEPRSTADQDKMAIALAKLAVEDPSFRVENDEESGQTLISGMGELHLDIIVDRMKREFSVDCNVGNPQVAYREAIRGTTEVEGKFIRQAGETGGRNQYGHVWLRLEPSEPGEGFVFVDEIADGSVPKEFIGAVATGIEEQMKSGVLAGYPMVDVKATLFDGSYHDADSTEIAFKIAASMALRQGALQADPVLLEPMMKVEVTTPEDWMGDVVGDLNRRRGMIEGMDEGLAGIKIIRAKVPLSAMFGYATSLRSATQGRASYSMEFSEYAEMPKNASDKIIAERS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1S4</accession>
    <name>D0Z1S4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative integrase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003488</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303586.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003488"/>
    <dbReference type="EnsemblBacteria" id="EEZ42455">
        <property type="protein sequence ID" value="EEZ42455"/>
        <property type="gene ID" value="VDA_003488"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4688">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="77366at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="791" mass="89776" checksum="7FAA6B64C0999360" modified="2010-01-19" version="1">MADVLIFKPKHELEYAKNQADFIEFGRQIAPLNDKYEYDQNYWQKVGNFNIFGVSNQSRNPEHLLDESLIPFAKAYVTYGGGTKAGLNVKFQALRAINASWQLLHKGEVFDAAKLTAKDFDAAQRAAKESLGAGAAYQAGRGLNNFLEFLIEYKLLKPFKWKSGIKKPSEQATDDDADKRRQDKMPDDNALMALASINARKTEELSPRDIFTTSTMALLMAAPNRGSEPLYLLADPLHYEELRVWEVLKIEGFTRDDVKAILEFQKEFDTASKTTDSAVFDESGSIIKSSQETESDNDKEELDLNATIRVIGLKWYSGKDFGHAHKWIPSCMYGVVEAAIARLQKQSEPARKFAKQLEDIPDFPRHDLCPDVPEDQPLTMDEVAMALGLDLSDYGDISDKENRKKWYSSRNSLLKRKGVERKDYVVTLRELNAILRNDLPEGFPYIPFKKGNGHVKVKWSEALYAGFANGLHTIKPTIQTELKIRTINTLNEDLAPTKKKSSTGKLAKGALSVFQRWGYGDLKITSHQIRHMLDTMAAVNGMDGEQRANWAMRSDPRHNRYYDHTTPEEYGADFICDHEADLVSRGLMVNPATGSTQIQVQIATPRTLQELNTKAALTAHTNEFGMCVTSYMAEPCTKYRDCINCDQQVCEKGDDGKCERIRTRLKDEKRLLKMDKKAVDDGIQGARQFYERRKLTTERCEQLLAMMEDPNIEDGSLIKLVNLEDDTQLDRAMDANGKKRLPKIENFQRIKANQRVSVDEMIGIESNSKSDIDDELFEAMDDLDCIDFFED</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1U7</accession>
    <name>D0Z1U7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0307 protein VDA_003511</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_003511</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0307 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303652.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003511"/>
    <dbReference type="EnsemblBacteria" id="EEZ42478">
        <property type="protein sequence ID" value="EEZ42478"/>
        <property type="gene ID" value="VDA_003511"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1711519at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16331">
        <property type="entry name" value="YjgA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.60.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00765">
        <property type="entry name" value="UPF0307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023153">
        <property type="entry name" value="PSPTO4464-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006839">
        <property type="entry name" value="Ribosome-assoc_YjgA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38101">
        <property type="entry name" value="PTHR38101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04751">
        <property type="entry name" value="DUF615"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016183">
        <property type="entry name" value="UCP016183"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158710">
        <property type="entry name" value="SSF158710"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="93"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ42478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="174" mass="20683" checksum="64A200044DF410AB" modified="2010-01-19" version="1">MSRKNKKAPWEEEEEIIWVSKSEMKRDMEELQKIGEELVELKPNALAKMPLDEDMMDAIKDAQRFTKEARRRQLQYIGKQMRFIDLEPIEAALDKLRNKHSQQTVMLKKLEQKRDKLIENGDSMINAILVDHPHADRQHLRQLVRQAGKEKAQQKPGKAFKEIFQYLKELYIQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z203</accession>
    <name>D0Z203_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Potassium channel protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001964</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299035.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001964"/>
    <dbReference type="EnsemblBacteria" id="EEZ40932">
        <property type="protein sequence ID" value="EEZ40932"/>
        <property type="gene ID" value="VDA_001964"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5032Y28">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1991946at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013099">
        <property type="entry name" value="K_chnl_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07885">
        <property type="entry name" value="Ion_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0407">Ion channel</keyword>
    <keyword evidence="3" id="KW-0406">Ion transport</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="193"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="Ion_trans_2" evidence="2">
        <location>
            <begin position="130"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="230" mass="25648" checksum="2F63377467A3921B" modified="2010-01-19" version="1">MVVKKKITESNNFFYLTLALIGLLISASLVQVTTSDILEYVLEAFTILTFVVCLVSLRFDQNWYRFLVTLLACWIGAIVVKKFFSLQQIDIAMLALMFAFFFGTFKSIAKQVLFSGPVTFNKIVGSVALFLLLGLMWAILYLILLEFDPNSFTGMESMPWGDNFSNAAYFSFVTLTTLGYGDISPITPIAQVIVYLEAIVGVFYMAIVVSSLVSSNQSYVEKNNQGNKNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z273</accession>
    <name>D0Z273_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Peptidase T</fullName>
            <ecNumber evidence="7">3.4.11.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_001918</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M20B family.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.4" evidence="7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298934.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40886">
        <property type="protein sequence ID" value="EEZ40886"/>
        <property type="gene ID" value="VDA_001918"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2195">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1015417at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045148">
        <property type="term" value="F:tripeptide aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006518">
        <property type="term" value="P:peptide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001261">
        <property type="entry name" value="ArgE/DapE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010161">
        <property type="entry name" value="Peptidase_M20B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42994:SF1">
        <property type="entry name" value="PTHR42994:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037215">
        <property type="entry name" value="Peptidase_M20B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01882">
        <property type="entry name" value="peptidase-T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00759">
        <property type="entry name" value="ARGE_DAPE_CPG2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="active site" evidence="5">
        <location>
            <position position="82"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="175"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="141"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="382"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR037215-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR037215-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="413" mass="45653" checksum="EA6B85952E168945" modified="2010-01-19" version="1">MNIVDRFLNYTRINTTTDREKGAAGIMPSSPGQMELALWVKQELEQLGLQDIELRETAILTATLPANTTKQIPTVSFFGHLDTSAEQKNDTHAHIVNYQGGDICLNPELDIILKASEFPEIAQYVDQEIIVTDGTSLLGADDKAAIAAILDALQYLQDHPEIEHGPVKVGFVPDEEQGLRGAKAFDVDSFGADFGYTLDCCGIGEFVYENWNAGNAEVTFIGQSAHPMSAKGKLKNSLLMAHKFIAMLPPGEAPEYTEGREGYYWVKELSGNSAKTVLKMDIRDFTKEGYRQRMTFLQQLADSCKTLWGENAIEIDLSDRYENVANSLEGEAHFPVDIAKEAYKRNNIEMKVTPMRGGYDGAVLSQKGLPCPNIFTGAHNFHSIYEYLPVNSLQAASDVVVEVIKITAEKMAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2A5</accession>
    <name>D0Z2A5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Lipoprotein putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_000556</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304713.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000556"/>
    <dbReference type="EnsemblBacteria" id="EEZ39536">
        <property type="protein sequence ID" value="EEZ39536"/>
        <property type="gene ID" value="VDA_000556"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4461">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009739">
        <property type="entry name" value="LprI_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018660">
        <property type="entry name" value="MliC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036328">
        <property type="entry name" value="MliC_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07007">
        <property type="entry name" value="LprI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09864">
        <property type="entry name" value="MliC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141488">
        <property type="entry name" value="SSF141488"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0564">Palmitate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019920" evidence="5">
        <location>
            <begin position="21"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="LprI" evidence="6">
        <location>
            <begin position="27"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="MliC" evidence="7">
        <location>
            <begin position="121"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF09864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ39536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="192" mass="21447" checksum="E897ED8C45CAA073" modified="2010-01-19" version="1">MKGKRFSLTLLSLFALPTLAATPSFDCTKASSSVEELICSNNELATLDNTLNTVYKQAMANYPSTEKKQQKAMQRGWIKGRNECWKSSDVLSCVADNYRDRILELQITGGLLKAPETITLQCNNEKQPVTVAFYNQTDPSSMVFTIGDDQLIAQQQPTASGIHYSGQNLEYIEHQGKIDITYMAKKLHCLVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2G0</accession>
    <name>D0Z2G0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">VOC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000611</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000611"/>
    <dbReference type="EnsemblBacteria" id="EEZ39591">
        <property type="protein sequence ID" value="EEZ39591"/>
        <property type="gene ID" value="VDA_000611"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="82" mass="9458" checksum="04A13502DDF0004A" modified="2010-01-19" version="1">MELELTWNEGVEEAYTHGSGYGHIAVAVDDLESEHEKLMGLGYEPADVKEFFRDGTLLAKFFFVQDPDGYKIEFLQRHGRYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2M1</accession>
    <name>D0Z2M1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HNHc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000672</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000672"/>
    <dbReference type="EnsemblBacteria" id="EEZ39652">
        <property type="protein sequence ID" value="EEZ39652"/>
        <property type="gene ID" value="VDA_000672"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502ZPCC">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13391">
        <property type="entry name" value="HNH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNHc" evidence="1">
        <location>
            <begin position="39"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="262" mass="30501" checksum="2AA40AA1F2E77708" modified="2010-01-19" version="1">MANKLRRAQVTETVKMSLVAEVQGKCPLCRKNLIKRKAPNVPVRVFDVAHIYPLNATERELELLKDEERLCDDIDSEGNFITLCKECHKMYDTQKTVEEYRHLVEVKKAINKIRALTDTWDNQTLHKDIALVAERIDQLDASTLEDTKLSFDALKVSDKTDDTFGQLNEMKVSMFVVNYFANIKESLKRLEMQRKASSLVICNQVRSYYSMLLFQDFNQNDIFEQMCDWFMVNTGIKERTKAEVLVSYFIQHCEIFSNDSAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2Q7</accession>
    <name>D0Z2Q7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Biotin_lipoyl_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000708</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000708"/>
    <dbReference type="EnsemblBacteria" id="EEZ39688">
        <property type="protein sequence ID" value="EEZ39688"/>
        <property type="gene ID" value="VDA_000708"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0845">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1432684at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039562">
        <property type="entry name" value="MFP_biotin_lipoyl_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13533">
        <property type="entry name" value="Biotin_lipoyl_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin_lipoyl_2" evidence="3">
        <location>
            <begin position="86"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="151"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="411" mass="45548" checksum="2BDF77CA62E14805" modified="2010-01-19" version="1">MFKKLMPFGIVLLSIAIATLLIIAKPEPKQKEPEQLIPTLEVVQVIKQDVPITIRAYGVVEPSRSADLVSELKGTVNWLSPKFEVGQFVKQGDVLLTLTDGDYQADLMQAKASLAQAKASLTEEIARGEVARKTLRNTQNTNALGLRIPQRQQEEANVEYAKAAVARAERNIAKTQIRAPFSGLISQKRIHIGSYINVGTQVGELLGTKIAHIRLAITPESFSLLPTPWPERYPVTLTTEVASHIHHYWQGELIRSEGVIDKNSRMVYLLAEVHDPYQLEKQSSRSLSAQPLQFGTFVSAQIRGKTIPNVIKLPRHVVRNRTVITIDENSKAKHQAVTVAREDLNYAYITDGLKDAEIVSLIRPEQIVDGLKVNVVESQSFDPSINVSIEADSGKLVPSLNSEPPNQEVVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2T1</accession>
    <name>D0Z2T1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative amino acid ABC transporter permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_000732</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000732"/>
    <dbReference type="EnsemblBacteria" id="EEZ39712">
        <property type="protein sequence ID" value="EEZ39712"/>
        <property type="gene ID" value="VDA_000732"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0765">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1523519at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010065">
        <property type="entry name" value="AA_ABC_transptr_permease_3TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043429">
        <property type="entry name" value="ArtM/GltK/GlnP/TcyL/YhdX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30614">
        <property type="entry name" value="PTHR30614"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01726">
        <property type="entry name" value="HEQRo_perm_3TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="35"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="94"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="133"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="185"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="232"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="285"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="8">
        <location>
            <begin position="88"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ39712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="319" mass="35742" checksum="61F09C882A454B76" modified="2010-01-19" version="1">MSQQTVSLPKLDKSTSSAPSQRSVLSRLSLRNLNGLDWSLLLLIASALGWFIYRSAVGIQYQWHWHQALELIFTAGPNGELPYFFQGVATTIRISLWGMLFAGVLGLLFGLARRSSLAFIRMPAQAYIQLIRNIPPLVFVFIFYFFISSQLVPLLGLETLFRYYNGTPNGLQTFLFGTPNLWENLFSGVICIGLLASAYIAEIIRSGIDSIEKGQWEAADSLGLTPLQRFRYVIFPQAFASVIPPLAGQFISIVKDSSIISLISIQELTFVGSEIANSSGYIFEIWILVGLAYLVLCLSLSILFSYLEKRYLKHQAYNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2W9</accession>
    <name>D0Z2W9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Iron-sulfur cluster assembly ATPase protein SufC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_000770</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily. Ycf16 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305295.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000770"/>
    <dbReference type="EnsemblBacteria" id="EEZ39750">
        <property type="protein sequence ID" value="EEZ39750"/>
        <property type="gene ID" value="VDA_000770"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0396">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1214676at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03217">
        <property type="entry name" value="ABC_FeS_Assembly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010230">
        <property type="entry name" value="FeS-cluster_ATPase_SufC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43204">
        <property type="entry name" value="PTHR43204"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01978">
        <property type="entry name" value="sufC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="2"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ39750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="247" mass="27558" checksum="37920AB85428034B" modified="2010-01-19" version="1">MLDIKNLHVSVEDNEILKGINLQIKAGEVHAIMGPNGSGKSTLSSTLAGKEDYEVTQGSIEFLNKDLIELDADERAGEGVFLAFQYPVEIPGVSNKLFLRTALNGIRNYKGLSELDRFDFDDLLEEKAEPLKMPVHLLDRSVNEGFSGGEKKRNDILQMAVLEPSLCILDETDSGLDIDALKAVSESVNTLRDDKRAFIVVTHYQRILDYIKPDYVHVMVDGKIVKSGDYRLAKELEEKGYGWIIGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z301</accession>
    <name>D0Z301_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000802</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305391.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000802"/>
    <dbReference type="EnsemblBacteria" id="EEZ39782">
        <property type="protein sequence ID" value="EEZ39782"/>
        <property type="gene ID" value="VDA_000802"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1661500at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="299" mass="33967" checksum="EC7AE6AD2034D4EA" modified="2010-01-19" version="1">MTNNQLFDGIIIFVQVVKSESFSAAAHLLGHSSSHVSKEVNKLENRLGVRLLNRTTRSLSLTPEGEAYFEQCIQLIQGAEDAVSLITHHEASPRGTLRINCPIGFSHQHLQPILVEYAKRYPNVILDLDLTDKRIDVIADGYDLAIRAAAQLDESSLICKAIYKSCIYTVASPDYLERKGRPYHPFELTKHDCICYSNLKSPYRWEYIDKSNQLINVDVRPRVKTNDGNIELAMTLAGQGICRLPEFYIADNLKTGQLEILFEDLPETEVNVYLLYPSRKHLSPKVRCFIDLIEEMLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z313</accession>
    <name>D0Z313_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4832 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000814</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305421.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000814"/>
    <dbReference type="EnsemblBacteria" id="EEZ39794">
        <property type="protein sequence ID" value="EEZ39794"/>
        <property type="gene ID" value="VDA_000814"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1874">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="469334at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032267">
        <property type="entry name" value="DUF4832"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16116">
        <property type="entry name" value="DUF4832"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003020033" description="DUF4832 domain-containing protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4832" evidence="2">
        <location>
            <begin position="313"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="504" mass="58463" checksum="9774140045B8ADFB" modified="2010-01-19" version="1">MKKTNLYYAALISSLIISQNAYSKQKQETINYYPETINDILVNPDIGITDFHTFDRRNDPWWSEPTHPETSVVYFRWYWEELETEEGKYNFQLIDDTINQAKNLGKKFVFRFMTMSGLNETYYNPSPLAGKKTLGIPCWLKKQIDPNTFDICKDDNSYVVDYKNPLLKEKLTKFVNAMGQRYNSNKNILRIDVGLVGTWGEWNLATHADHAELGQNGYTYEDLKPYVDMMHNAFPDQQLSIDLGSRSETIASDVTSRLNLGWRADCLGDWAPWGWNHMENGYPDTINFIEGNSTLANRHAYQNFSQHWKTAPVDFEVCTSLNDFSYEPNIYTRDKIKQTFDFALNKHASLLNIKSGNVPEMYQDLMDDFLKKLGYRFELSFVQLISNFKPGSNITINSTWKNVGSAPSYNNYPVSWRLINQKNNSIITWNTENDITKWYPAEDINQDAHNYNQNNIFSLPVNMQTGMYKLQVALLDKNNNPAIKLGIFGRDNDGWHTIGDVYIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z314</accession>
    <name>D0Z314_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glyco_hydro_42 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000815</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305424.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000815"/>
    <dbReference type="EnsemblBacteria" id="EEZ39795">
        <property type="protein sequence ID" value="EEZ39795"/>
        <property type="gene ID" value="VDA_000815"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1874">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="469334at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009341">
        <property type="term" value="C:beta-galactosidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004565">
        <property type="term" value="F:beta-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013529">
        <property type="entry name" value="Glyco_hydro_42_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02449">
        <property type="entry name" value="Glyco_hydro_42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018864" description="Glyco_hydro_42 domain-containing protein" evidence="1">
        <location>
            <begin position="26"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_42" evidence="2">
        <location>
            <begin position="85"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="362" mass="41695" checksum="CB5E8F5AA078E232" modified="2010-01-19" version="1">MPKSYIIPVLSLSILLGCNDSSSNANTLPLLPDNIQSITPLINSNVLVNPDIGFTDLSSIHIHDDPYTPVPSYPVTSVVYYRWYWEQLEPRDGEYDFSVIDTALKDAIKHNKKLVFRIMTLAAPGETYYGELGFNFQPILGVPCWIKDQLSSTIPSGQWEGCSTNAEFIPDYNQPYFKEKVAQLMQALGDKYDGNNNILRLDVGLVGTWGEWHMASRTIQTPQHPDLISQGYTNEELFYYVDLVEKTFPRTTKTMLINSKDEDTLSYATLKGFGWRADCLGDWAEWGWNHMEQGYPYAIEHTKGSGPYPNEYPDYEFDHRWQQKPVDFEICETMEDWSYNPELYTQEKVKESFDYALKKQTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z356</accession>
    <name>D0Z356_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Paraquat-inducible protein A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_000857</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PqiA family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305545.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000857"/>
    <dbReference type="EnsemblBacteria" id="EEZ39837">
        <property type="protein sequence ID" value="EEZ39837"/>
        <property type="gene ID" value="VDA_000857"/>
    </dbReference>
    <dbReference type="GeneID" id="57343105"/>
    <dbReference type="eggNOG" id="COG2995">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="836803at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007498">
        <property type="entry name" value="PqiA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005219">
        <property type="entry name" value="PqiA-like_Ent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04403">
        <property type="entry name" value="PqiA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00155">
        <property type="entry name" value="pqiA_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="60"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="106"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="189"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="276"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="315"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="373"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="400"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ39837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="447" mass="49683" checksum="0A7BD00A4B8977E7" modified="2010-01-19" version="1">MVSLEQTTATTASLPHELIACEECGLVVDIPDIKDGQKATCPRCGHTLLKKINNPYHKPIAYGIACLIMLVLSVSFPFMSFSVQGLTHEITLANAAEMLRHFDNGILSALFMGFVLVLPAFYVLAIMYLNYQAAKIHQGHYDVKNIETIKSLCRIIFKIEPWTMVDVFLIGVLVSLVKIAALADVGLGSSFWAFCAYTILFVKCVSLIDRTWLWDQFIPMTHIAGVKPGDDHSTHNHVACHTCNQLNPMPTTKHAKCLRCDSRLHVFDPRMNLQRAWAFLIASIVFYIPANLYPMMYTVSLGQKDGSTIMGGVALLWHLGSYPVAAVIFFASIMIPMAKMFALMWLYYSASKKPDCSQRDAIQHLKLYRITELIGRWSMIDIFVVSILVALVQLQNLMAILPGPAALSFAAVVVFTMLSAMTFDPRVFWSNTDLKSSADGKASAAIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-02-10" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3D1</accession>
    <name>D0Z3D1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Replication protein P</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000932</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305758.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39912">
        <property type="protein sequence ID" value="EEZ39912"/>
        <property type="gene ID" value="VDA_000932"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502ZB3U">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1934526at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009731">
        <property type="entry name" value="Phage_lambda_P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06992">
        <property type="entry name" value="Phage_lambda_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="219" mass="25370" checksum="5E1898320C8E9650" modified="2010-01-19" version="1">MDNIVELTEKIAVNTKHRPVYVAQYAKHIDEFAMQNINAIFKDLCAIFPAWRNHLRTSEEFRATRANFAKGMIENEITTMEQVRRGLARARQQESDFFPSVGKFISWCQDLDSWEDAFKRMLCNEPALSLAEKLTRNELSWPTRHLLTEYEALSRFKKLLIKYQSLERDGFLRDLPQLPRQSVVTDIDIKRNSVSVSPSSFKKGSVFARVAARGEMIHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3M8</accession>
    <name>D0Z3M8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Riorf46 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000031</name>
        <name evidence="4" type="ORF">VDA_000122</name>
        <name evidence="5" type="ORF">VDA_000243</name>
        <name evidence="6" type="ORF">VDA_001029</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000005">
        <property type="protein sequence ID" value="EEZ39046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39046">
        <property type="protein sequence ID" value="EEZ39046"/>
        <property type="gene ID" value="VDA_000031"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39106">
        <property type="protein sequence ID" value="EEZ39106"/>
        <property type="gene ID" value="VDA_000122"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39227">
        <property type="protein sequence ID" value="EEZ39227"/>
        <property type="gene ID" value="VDA_000243"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40009">
        <property type="protein sequence ID" value="EEZ40009"/>
        <property type="gene ID" value="VDA_001029"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2801">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1637053at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="2">
        <location>
            <begin position="128"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="408"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="454" mass="53133" checksum="D7651E3EA6B28C9A" modified="2010-01-19" version="1">MLLTMTDNELLRIKVIQDICDKRLTGVEAAHLLNLSPRQVYRLVKRFIEFGASGLVSLQRGRPGNHRYDENVKLQTLAILYEHYTDFGPTLAHEKLTERHNIHVSVETIRQWMIADGLWVPHTKRKPRVYQPRYRRDCLGELIQIDGSHHDWFEGRSNKCCLLVFIDDATGKLMNLRFSETESAFDYMVATREYLEQHGKPTAFYSDRHAVFHVSKRDAKTERLTQFGRVLHDLNIELICANSSQAKGRVERANKTLQDRLVKEMRLQGIDTIEQANVWLPDFIADFNRRFAKPAKYPKDMHRPVREMTDELNDIFAWQELRKLSKSLTFQYDKVVYLIDPTEENQRLINQVVKVLDRPDGTIAIQYGQRKLTFKVFDKLADIDQGQIVDNKRLGAVLKFAQEKQQEFEQQQTRSRSKKAPKRTAQQRAIRQLEAINPVLVHPEQFKPSTRKKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3N3</accession>
    <name>D0Z3N3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001034</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306040.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001034"/>
    <dbReference type="EnsemblBacteria" id="EEZ40014">
        <property type="protein sequence ID" value="EEZ40014"/>
        <property type="gene ID" value="VDA_001034"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2354">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1419056at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008526">
        <property type="entry name" value="YedI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30503">
        <property type="entry name" value="PTHR30503"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05661">
        <property type="entry name" value="DUF808"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016660">
        <property type="entry name" value="YedI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="165"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="226"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="267"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="298" mass="31596" checksum="93EDFFB1924E579A" modified="2010-01-19" version="1">MAGASLLTLLDDIATVLDDVALMTKVAARKTAGVLGDDLALNAQQVSGVRAEREIPVVWGVAKGSFRNKLILVPAAILISVIAPWLISPMLLLGGLFLCFEGAEKILEKFFHHEEHNEEAKVEPEIVDIEQFEKEKIKGAVRTDFILSAEIIVIALGTVQDHPLMTQILVVSLIAIVMTAGVYSLVAGIVKLDDAGLYLVNHSEKETLKHRIGGALVSVAPYLMKALAVIGTIAMFLVGGGIVVHSIPQSHDIIHHLTETVSFPGAASILPAAINGVIGIIAGLVVLAVVTLVKKIKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3R4</accession>
    <name>D0Z3R4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_001065</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306128.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001065"/>
    <dbReference type="EnsemblBacteria" id="EEZ40045">
        <property type="protein sequence ID" value="EEZ40045"/>
        <property type="gene ID" value="VDA_001065"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1971">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1993813at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003810">
        <property type="entry name" value="Mntp/YtaF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35529">
        <property type="entry name" value="PTHR35529"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02659">
        <property type="entry name" value="Mntp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="69"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="100"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="128"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="184" mass="19967" checksum="EC277D1B35805384" modified="2010-01-19" version="1">MTFLLALLFSLSSNLDNFVIGFSYGVKHKQISLLSNTIIATIIAVVTYLSMILGQWLTHLISHQESSDIGSIIFIGLGIWSIGNSFSNKKKTQKNDTKELGIKGAIILGILLSINNIGVGILGSVSRLNITLITVLTFITSILLIYLGNHLGNHIIGRLLGRYNDLVSGLLLVILGLLSFIYAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3S4</accession>
    <name>D0Z3S4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase</fullName>
            <ecNumber evidence="6">5.3.1.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">5-keto-4-deoxyuronate isomerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">DKI isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">kduI</name>
        <name evidence="7" type="ORF">VDA_001075</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>5-dehydro-4-deoxy-D-glucuronate = 3-deoxy-D-glycero-2,5-hexodiulosonate</text>
            <dbReference type="Rhea" id="RHEA:23896"/>
            <dbReference type="ChEBI" id="CHEBI:17117"/>
            <dbReference type="ChEBI" id="CHEBI:29071"/>
            <dbReference type="EC" id="5.3.1.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 6">Glycan metabolism; pectin degradation; 2-dehydro-3-deoxy-D-gluconate from pectin: step 4/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the KduI family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.17" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306156.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001075"/>
    <dbReference type="EnsemblBacteria" id="EEZ40055">
        <property type="protein sequence ID" value="EEZ40055"/>
        <property type="gene ID" value="VDA_001075"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3717">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1047507at2"/>
    <dbReference type="UniPathway" id="UPA00545">
        <property type="reaction ID" value="UER00826"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008697">
        <property type="term" value="F:4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045490">
        <property type="term" value="P:pectin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.520">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00687">
        <property type="entry name" value="KduI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007045">
        <property type="entry name" value="KduI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021120">
        <property type="entry name" value="KduI/IolB_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027449">
        <property type="entry name" value="KduI_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38461">
        <property type="entry name" value="PTHR38461"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04962">
        <property type="entry name" value="KduI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006625">
        <property type="entry name" value="KduI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="243"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="276" mass="31064" checksum="C1A9F7B96E5EB902" modified="2010-01-19" version="1">MEIRQPIHSAHAKQLDTAGLREQFLIEDLFQAGQINLTYSHIDRIIVGAAVPTETAIAFEGGKEIGVDFFLQRRELGIINIGEPGLVVVDGQTYEIGAREAIYVGMGAQDIRFESVSAEQPARFYLNCAPAHHAYPTRKITREDAAPETLGNQENCNVRTIYKYLHPAVLPTCQLLMGMTELAPGSLWNTMPCHTHERRMEVYLYFDMNQDNVVFHYMGEPQETRHLVVRNEQAVISPSWSIHSGVGTAAYTFIWGMVGENQTFHDMDHVAMSDLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3U0</accession>
    <name>D0Z3U0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Surface protein Lk90-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001091</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306199.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001091"/>
    <dbReference type="EnsemblBacteria" id="EEZ40071">
        <property type="protein sequence ID" value="EEZ40071"/>
        <property type="gene ID" value="VDA_001091"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502ZXPB">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="169533at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="816" mass="91371" checksum="C3DCBB100615FA6A" modified="2010-01-19" version="1">MEKIKTIVFVIVSSLLFGCNGSDGGEGTIKDDFYFNVENSFHHVILSNDKSKHIDLSDNIHKQGSGSVSIKNVTILSGDCSAPIIDDLSLVITDNKSNLCKVNVEYVSDNNIQKSSNVTYIVSAGEQGDILPILNLDKSIEQANAPLVIDLKSSLGSDYPFDYHLVSSSVVGNGQVDNDITNDTLSFSTDMIGSDRVYYSLESDNPENKSVYGYINVNISSDDIIPPQANDIALEKDVVAGETITVNLNDLDAIKEGSVPLSEVQLTDVYMLDTYDAASVKIDNQDDLRNVEFSFQSQYQGKYYVSDYISDHLGNSDIGIVEINVKPAYDLIFLPNVGIFTAPLTAYDVLDTRYERPDPSHIYTEDGSNGPNGLDIALFSQTDAQQYCSDIGMTLATGIQLEQLDRSASGSTLFDKYNWPQSHIFWGLENKGAFDFKTHQWIEETSTTTGYFTCVMQVESDQVTIHSKDKLYVGQNDDAYLTTKLDSGEEIVIPDEYVNYSVGNDNILNIDVNNGDITALKSGLTNITGTLIDSPVSDSKQVEVIDYPIIEMRVRPFVSVKETIPVTFEISYNSGKSWQPLPEDIVVQSVSMEPEGPAVITKDGSNQFNLTGVQEGLVTLTAHTNHSEIDQYIKPHDVRVFAKNVDVCLQFAYFDRIHGRKFCLAYDEGRFFEVPGLEDLILSRRWFANNNPRVLYTNQKEYCRLIGGNEYLIPHDYGKAYPLDGWIFGLSDENIYIHRVVKENYEEGQDKPGRKMEWSGIGPWHWERWRWGGAGTPSEKIAPTCMYEDIHVNPSESTKKRFENYKQMVRNVVLIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3U7</accession>
    <name>D0Z3U7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATP synthase subunit epsilon</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001100"/>
    <dbReference type="EnsemblBacteria" id="EEZ40078">
        <property type="protein sequence ID" value="EEZ40078"/>
        <property type="gene ID" value="VDA_001100"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0355">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036794">
        <property type="entry name" value="ATP_F1_dsu/esu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020547">
        <property type="entry name" value="ATP_synth_F1_dsu/esu_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00401">
        <property type="entry name" value="ATP-synt_DE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46604">
        <property type="entry name" value="SSF46604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-synt_DE" evidence="2">
        <location>
            <begin position="5"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="56" mass="6361" checksum="2348C14CF3FDE326" modified="2010-01-19" version="1">MHGKDIDKARADEARRAAEENINKHADDVNFAQAQMELAKAMAQLRAVELTQQVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3W3</accession>
    <name>D0Z3W3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Multidrug resistance efflux pump</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001116</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306265.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40094">
        <property type="protein sequence ID" value="EEZ40094"/>
        <property type="gene ID" value="VDA_001116"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1566">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="757027at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039562">
        <property type="entry name" value="MFP_biotin_lipoyl_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13533">
        <property type="entry name" value="Biotin_lipoyl_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="domain" description="Biotin_lipoyl_2" evidence="2">
        <location>
            <begin position="65"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="3">
        <location>
            <begin position="157"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="377" mass="42189" checksum="4A15B0C60A3B17C2" modified="2010-01-19" version="1">MDLLLILTYTALCIAIFKIFRIPLNKWTVPTAVLGGVVLIGTLILLMNYNHPYSNLGGQYFVTTPVIPAVRGKVIEVPVEANRPLHKGDVLFKLDPTPFQAEVNLQQAALAEAQQYVLGLEAAYRAAQATTHKAQAERDRTYTQYQRYKKGHQKGAFTQSDVDNRRQFYLSAESSLEAAKAEERRAKLAFESEIAGENTNIAKIRAQLQKAQFNLDETVVHAPTDGYVTQLALRPGMMAVPMPLRPVMTFVNKDAENLFVAAFRQNSLLRLEKGFKADFIFKALPGKTFAGEVVEVLPAIGESQIQAQGTLYGTEALQRQGRPLVVLKITDDIGQYQLPQGTNVEVAIYSDSFEHVAVMRKVLIRMKSWQNYLYLDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3W7</accession>
    <name>D0Z3W7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Trehalose-6-phosphate hydrolase</fullName>
            <ecNumber evidence="2">3.2.1.93</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.2.1.93" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001120"/>
    <dbReference type="EnsemblBacteria" id="EEZ40098">
        <property type="protein sequence ID" value="EEZ40098"/>
        <property type="gene ID" value="VDA_001120"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008788">
        <property type="term" value="F:alpha,alpha-phosphotrehalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032091">
        <property type="entry name" value="Malt_amylase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16657">
        <property type="entry name" value="Malt_amylase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aamy" evidence="1">
        <location>
            <begin position="1"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="356" mass="41420" checksum="CB2DFFD8F4F96F59" modified="2010-01-19" version="1">MINLISKQQDFPNDDQGDGRRFYTDGPRVHEYLQEISRDVFQYYGSVTVGEMSSTTLERCQQYSALDGSELSMVFNFHHLKVDYPQGEKWALAPFDFVGLKQIFSHWQRGLHCKGWGALFWCNHDQPRIVSRLGNDGAYRELSAKMLATSLHMMQGTPYIYQGEELAMTNPHYQNLSQYRDVESLNMYKIMVHQQGIEPTTMLNILAEKSRDNSRTPMQWSDALHAGFSKEQPWIDVADNYLLINAEQAIKDPNSVFYFYQRLIELRKTVSIITDGDFLDLCPEHPQLFCYLRQANGQHLLCINNFYDKQVEFELPENIDVSKGKVLLGNYDDWQTQTVQSSMLVRPYESRVILFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z409</accession>
    <name>D0Z409_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uracil-DNA glycosylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001162</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306380.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40140">
        <property type="protein sequence ID" value="EEZ40140"/>
        <property type="gene ID" value="VDA_001162"/>
    </dbReference>
    <dbReference type="GeneID" id="57343361"/>
    <dbReference type="eggNOG" id="COG1573">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1529383at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005122">
        <property type="entry name" value="Uracil-DNA_glycosylase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036895">
        <property type="entry name" value="Uracil-DNA_glycosylase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03167">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00986">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52141">
        <property type="entry name" value="SSF52141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDG" evidence="1">
        <location>
            <begin position="27"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="195" mass="22409" checksum="2CE2011CE0A6FC4F" modified="2010-01-19" version="1">MSVENLVHRIRQCQICKGKLPYPPKPLIQASDKAKILIIGQAPGEKTHFKGRVFDDVSGDRLRAWLGVDRETFYNPDIFNIVPMGFCYPGTIIRNGKRAGDKPPRPECRATWHPILLPQLTQVELVILMGNYAIEYYLKQKKLSVTDAVFNQDHHKDNIFVLPHPSPRNNIWLAKHPQFEQDILPKLKQKVAQLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z441</accession>
    <name>D0Z441_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000297</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303976.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39279">
        <property type="protein sequence ID" value="EEZ39279"/>
        <property type="gene ID" value="VDA_000297"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1675292at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018832" evidence="1">
        <location>
            <begin position="20"/>
            <end position="621"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="621" mass="68604" checksum="1549B0B0B7E6FB6C" modified="2010-01-19" version="1">MIFNKKLISLAIISSLSLAGCGGGGNDEKQETPTDAGGAIITVRYIDSAVTGLNYQCDQTEDGKTNNNGEFTTVNNAQCNFFINDLNIGSAIIKKSQINQNGIVIIDPISMTKQQNVRYENIAVLLQSLDNDGNSENGINLENANIKAPLSTKDHNLLTMSASELQKQLQTLVKNPKTIVTEQQALAHLHQSLTTSGALAGYHSPQVQEIVTDINKLSTSTPEEMQQINFVDKVQQYQDILDSGASDNADIEVLKAVLTIAKIVNEPEVKERISFNYENTNLANETEDLLPQVLDSLLKANGPLLVPNELEKGSTDSEAKILYSLAQNLMTASNTLGQSFTNINRVASYDTEGKIQLNYQRAQSLRVIALSIANSLSTAAAYDLGSDKYFIPQRERVTIPLTIAQDYFTVVGEKKTTVNSEFATAEEDPVSLIADQSFMTLRNSGPEYLRTALSALKQAASIAATQINLDDKEFSNLTGADKQNLKAMIDSLNHHLQSSDGQKNPFTYTVLDQNGKVDGELTINLQEFYQNPITRNDITITENKYNCTIDKNLSKYMNQPMCYEKGDTNFWYGYEDLSSNKMLFVSGQPAKHLFSSDYTNTNIILSCREKDSNNNWVFCEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z458</accession>
    <name>D0Z458_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Arsenical-resistance protein ACR3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_000314</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304018.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000314"/>
    <dbReference type="EnsemblBacteria" id="EEZ39296">
        <property type="protein sequence ID" value="EEZ39296"/>
        <property type="gene ID" value="VDA_000314"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0798">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1493959at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015103">
        <property type="term" value="F:inorganic anion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004706">
        <property type="entry name" value="Arsenical-R_Acr3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002657">
        <property type="entry name" value="BilAc:Na_symport/Acr3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43057">
        <property type="entry name" value="PTHR43057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01758">
        <property type="entry name" value="SBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005508">
        <property type="entry name" value="Acr3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00832">
        <property type="entry name" value="acr3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="25"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="58"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="152"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="195"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="234"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="264"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="297"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="326"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR005508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="357" mass="39201" checksum="4D2B06A288C40CD2" modified="2010-01-19" version="1">MSTQPLPTSTEASAPVKMSFLDRYLTVWIFAAMATGVLIGAVFPQVSHWNEAMSVGNTNIPLAIGLILMMYPPLAKVDYSLLKSVTKDRQAMTLSLVMNWIVGPILMFVLALTFLGDHPGYMVGIILIGLARCIAMVLVWNDIGGGNKEYGATLVALNSAFQIITYSFMAWLFISVLPPYFGYQGFAIDISMLDIAHSVLIYLGVPFVAGFLSRKYLVKFKGQDWYNQVFIPKISPITLIALLGTIILMFSLKGEMILELPMDVVRIAIPLAIYFVVMFFVSFFIGKKMGISYDKNASIAFTATGNNFELAIAVSIAVFGLNSDQAFAGVIGPLIEVPVLIGLVNLALRMKQKYNLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z492</accession>
    <name>D0Z492_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Hypothetical permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_000348</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0014 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304114.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000348"/>
    <dbReference type="EnsemblBacteria" id="EEZ39330">
        <property type="protein sequence ID" value="EEZ39330"/>
        <property type="gene ID" value="VDA_000348"/>
    </dbReference>
    <dbReference type="GeneID" id="57343272"/>
    <dbReference type="eggNOG" id="COG0390">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1882150at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005226">
        <property type="entry name" value="UPF0014_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30028">
        <property type="entry name" value="PTHR30028"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03649">
        <property type="entry name" value="UPF0014"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="93"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="127"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="180"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="220"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="255" mass="27679" checksum="8229F25A1B2F9A80" modified="2010-01-19" version="1">MNGAVNISVWALAGFYGLLLIPIYFFFRWQLKLTRSLITAVLRMTIQLAVVGLYLHTLFSLNHIGLNVLWLSVMISVAGYTVCKRAGVELKTVLPAVLIGLVVALVIALPAMLAGVIQATPWWDAQYMIPIAGMLLGNSLSANVLALERWQSQLKEKHQEYQFYVAMGAPNPSQPFIKTAMGAAVLPQIAAMTTLGIVSLPGMMTGQILGGTAPLIAVKYQLAIMVAIFISGILSVATTLTLIQRRTFSEYGEVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4F7</accession>
    <name>D0Z4F7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000413</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39395">
        <property type="protein sequence ID" value="EEZ39395"/>
        <property type="gene ID" value="VDA_000413"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031EJ3">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="277" mass="32127" checksum="FF5F90F264111D6D" modified="2010-01-19" version="1">MAFEIYLELLGENWLALENLIKLGLINLFFIGLELFLLFEVGFITTAILINRASAQYQFCDKMKASLVRAVMELSEPTDNIHGIKPYKQYSKFRYIKVALYTGKDILSNFVIKAILQKSISRSSVRVYIPLVSTLITGFWDAWVQQKALSEVRLRISARVYVLNQLAELEAKDMSQAYVTALLRLIAVRQSYKQECDVNLEYFYDQLYKSKQYQLNDLESVDLLLISVNALTNEEKTELTVMMEYLFYFRRNPTRNEKALLYKLGVLQASKNNPLLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4T2</accession>
    <name>D0Z4T2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">IncF plasmid conjugative transfer pilus assembly protein TraC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000165</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000165"/>
    <dbReference type="EnsemblBacteria" id="EEZ39149">
        <property type="protein sequence ID" value="EEZ39149"/>
        <property type="gene ID" value="VDA_000165"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3451">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043964">
        <property type="entry name" value="P-loop_TraG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014117">
        <property type="entry name" value="TraC-F-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025955">
        <property type="entry name" value="TraC/Conjuga_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045978">
        <property type="entry name" value="TRAC_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19357">
        <property type="entry name" value="DUF5934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19044">
        <property type="entry name" value="P-loop_TraG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11130">
        <property type="entry name" value="TraC_F_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02746">
        <property type="entry name" value="TraC-F-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5934" evidence="2">
        <location>
            <begin position="279"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="domain" description="P-loop_TraG" evidence="1">
        <location>
            <begin position="452"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF19044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="692" mass="77998" checksum="39B06249E59B560C" modified="2010-01-19" version="1">MSSVIARGGLNTLYKRAHPVASHMHQELPYRYYDDESGLFENQSTLGFGKKLNVLGGANDELVAALNELVMRLPEGKNWDFQFVLTGDNQVGHIIDSNYEQASVRGGIVEKIAQNQAIYAHYAARNGYNTKLGPSYRFDLKNYNASFFCTSKADRETVSDLKTTLDYAFVQTGIDHQPIEPHDLIDNVSQALNFNSARNTPKRPHYNEDELLHSQMLELDSEFLIHKKYIESRCSFAHQDEVAHTRVINFTLRRLPSEFRLYSFSNCLASLRNAANALRCPFRISCNFQIEPTGKEKVKNEGKIRNLSKWAHSPMAIFIPTAKKELQEREELQDAFLREECKIASMVFTITLFSNKENMKADMASARGVFSEAGLPIVEADMIQGQTLLASLPFNMIDFYDDCRKAGRVRQIKTSNLVNFFPIVAEYKRIMGGMLLPTMRHQISYFDPFNMSTDNYNMAITGVSGSGKSFITQNIARSVFERGGKVWILDKGDSYKKFTQTMSGVYMTAGSVFLNPFTHIATVEQKAGISFSEASNLKPSEGHDDDDVHPLASILGDITGLIASMAAPNTDLNDTLDSALSDAILRAWDRHKQNTLIDHVQEALFELAKERDDDRRISDLGHQLNKYCTDGIYGDIFNKPSQLDPDVHLTTIELEGFTDNVLRPVIFALMVSINQAMYLAGERRIPKVCIIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4U0</accession>
    <name>D0Z4U0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">KilA-N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000173</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306509.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000173"/>
    <dbReference type="EnsemblBacteria" id="EEZ39157">
        <property type="protein sequence ID" value="EEZ39157"/>
        <property type="gene ID" value="VDA_000173"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502Z7N4">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="872571at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017880">
        <property type="entry name" value="KilA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018004">
        <property type="entry name" value="KilA_N/APSES_HTH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04383">
        <property type="entry name" value="KilA-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01252">
        <property type="entry name" value="KilA-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51301">
        <property type="entry name" value="KILA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="KilA-N" evidence="1">
        <location>
            <begin position="1"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="276" mass="31775" checksum="8E4903EF7D1E3F4F" modified="2010-01-19" version="1">MAQKIDVRGVKVSVFSDKQDDYISLSDIAKYKDGDRSDYILQNWMRNRSTIEFIGLWEQLHNPDFNSIEFDGFKNEAGANSFSLTPKRWITATNAVGIISKAGRYGGTYAHQDIAFEFASWISAEFKLYLLKEFQRLKQEENEQKNLEWNVSRTLAKVNYHIHTESIKTNIIPTLELNPKAKNFVYANEADMLNLALFGKTASDWRKENSELKGNIRDYATLEQLVVLSNLESFNAELIEQGISTNDRFQKLNSVAVNQMKILIENKSIDKLKQLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4U1</accession>
    <name>D0Z4U1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tn5044 transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000174</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000174"/>
    <dbReference type="EnsemblBacteria" id="EEZ39158">
        <property type="protein sequence ID" value="EEZ39158"/>
        <property type="gene ID" value="VDA_000174"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4644">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025296">
        <property type="entry name" value="DUF4158"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13700">
        <property type="entry name" value="DUF4158"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4158" evidence="1">
        <location>
            <begin position="3"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="179" mass="20628" checksum="4E9F3D8044940513" modified="2010-01-19" version="1">MASIDRTASPRFYKQLSEKELSDHYVLDDKELSFARRNTRSDRGYLIIAVMLKTRRQLGYFPALNKIPVQIIFHISKQLNLTSIVWKADEKHDGKMLHRYRSSCRKFLESSPFTEKGKKLVITSVRNAALTMSDPADLINVAIEALVNSGIELPAFSTLDRLVSHERHLIHEKLYLEIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4X1</accession>
    <name>D0Z4X1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Beta/gamma crystallin 'Greek key' domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_000204</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the beta/gamma-crystallin family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39188">
        <property type="protein sequence ID" value="EEZ39188"/>
        <property type="gene ID" value="VDA_000204"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3342">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001064">
        <property type="entry name" value="Beta/gamma_crystallin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011024">
        <property type="entry name" value="G_crystallin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00030">
        <property type="entry name" value="Crystall"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00247">
        <property type="entry name" value="XTALbg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49695">
        <property type="entry name" value="SSF49695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003020016" description="Beta/gamma crystallin 'Greek key' domain-containing protein" evidence="3">
        <location>
            <begin position="22"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="domain" description="Beta/gamma crystallin 'Greek key'" evidence="4">
        <location>
            <begin position="262"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="353" mass="39870" checksum="91F13F623CFD12CE" modified="2010-01-19" version="1">MIRKSISIPVVISILSSPSFAHDDVFSQQEEVNFNKTYSSCSVPSDDFVFYRAQSEQVNQIRSEAEALLFDVNRKLNITDKRDILGLCNAVKMATDDDFDVIKNKILSVDHIGYGGFDTTNDVARNQVGAFNSIVVDFLLKNKTKEPEQLIDLICLINNADNTAYSKINTAIYVDYIDNNNGWEQIQNKGKSSCYPIYKGGVHTWLKMNASYLEKSGKLDEAREVYVLLNKYFKRIRTLHTGDIVRLSQPTVATQAQDNGQFVTIFEHDNFQGRAKKIIGDIVDLGDFNNQMSSYKIPKGWQVRFYEGANFQGGFYTRSSDGWDSTFTAGFNDKIKSIKIIKKEGSVAKLGNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z524</accession>
    <name>D0Z524_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000257</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306756.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39241">
        <property type="protein sequence ID" value="EEZ39241"/>
        <property type="gene ID" value="VDA_000257"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502ZXQR">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1403295at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021316">
        <property type="entry name" value="DUF2913"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11140">
        <property type="entry name" value="DUF2913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="199" mass="22820" checksum="3A313CCF90505AF4" modified="2010-01-19" version="1">MFNSPYHALLSDAVDNALLHLYSEVSASTRFFPTIKRNEILVRYLKPKLKSPKYKLVKAELKIMIGIGRNPEGNLEAKLIELNQLANKNRQNTTDAHSLFQLMELLDAEHNFDSKLFNPDIISVADVIYILPEHIEHCFADDGKQVAPVSLFIESDRTTELLLAIDNSELFTTELKEWNEQKKQAHILLHPIKAEKNTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z530</accession>
    <name>D0Z530_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF1281_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000263</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306770.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39247">
        <property type="protein sequence ID" value="EEZ39247"/>
        <property type="gene ID" value="VDA_000263"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1948306at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041329">
        <property type="entry name" value="YubB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18406">
        <property type="entry name" value="DUF1281_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1281_C" evidence="1">
        <location>
            <begin position="137"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="214" mass="25626" checksum="E64817CC58E3D98E" modified="2010-01-19" version="1">MPNHIPDHILNVISIDSDDRQQSEQGILSILDNQGVFDFNRYIPMPRILRNTQAPNRINPDECRNKTGYIDWYEWSWDNWDTKWNAYNQNIEYDGLDAKPWHLSCKTKNIICNSKYRAYLKRQNKKRFKASIIENGVPEHVKFYSAWVHPEKVIIAMSKKHPSFYFRVKFADEDIGYDVGEYVIKNGKLFDVRRDINFEHKEEAFAKKLWNEYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z567</accession>
    <name>D0Z567_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted manganese transporter 11 TMS</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000117</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306898.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000117"/>
    <dbReference type="EnsemblBacteria" id="EEZ39101">
        <property type="protein sequence ID" value="EEZ39101"/>
        <property type="gene ID" value="VDA_000117"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2248">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1784762at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021552">
        <property type="entry name" value="ArsP_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11449">
        <property type="entry name" value="ArsP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="209"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="240"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="290"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="316"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="379"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="403" mass="44035" checksum="E9DEB15C0612BBEF" modified="2010-01-19" version="1">MDTSIQKLSKLAQQQSWQLTNKRLILPVIILVLLISTSSLRELTIQVLADGFWQVAAYVAATLAVYEFISTKLKHRESPITKLIEHSVIGQIVFSALMGALPGCGGAIIVMTQYVNGKLPFAAVVTVLTATMGDAAFLLLATKPSVGLFVIMISTVVAILSGLVIYKAHGVHFLKRVQHVNEFVEIQNCCRQSSSQDTTPILIKLQSKFWQWILIPAITIALLGSFQIDTNHLFNLPANTIEIVGAVAAIITIFLWALSREVSDYQSMVSEDPKKPNDKAFNRIALDTNFVLSWVIGAFLAFELMLYWTQIDLNQLFNHWGILLPLIGIAIGLLPGCGPQIIVTSMFLAGTIPLSAQLGNAISNDGDALFPAIALAPKAALIATLYSSIPALLTAYTYFYLFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z580</accession>
    <name>D0Z580_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000011</name>
        <name evidence="2" type="ORF">VDA_000040</name>
        <name evidence="3" type="ORF">VDA_000130</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000008">
        <property type="protein sequence ID" value="EEZ38985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="ADBS01000005">
        <property type="protein sequence ID" value="EEZ39055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000011"/>
    <dbReference type="EnsemblBacteria" id="EEZ38985">
        <property type="protein sequence ID" value="EEZ38985"/>
        <property type="gene ID" value="VDA_000011"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39055">
        <property type="protein sequence ID" value="EEZ39055"/>
        <property type="gene ID" value="VDA_000040"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39114">
        <property type="protein sequence ID" value="EEZ39114"/>
        <property type="gene ID" value="VDA_000130"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1463">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021856">
        <property type="entry name" value="DUF3465"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11948">
        <property type="entry name" value="DUF3465"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ38985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="40" mass="4925" checksum="8BACB630176890F2" modified="2010-01-19" version="1">MQFYGEYEWNHQGGVIHWTHKDPKQKHPDGWLKVNNVKYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z584</accession>
    <name>D0Z584_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">IncF plasmid conjugative transfer pilus assembly protein TraF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000015</name>
        <name evidence="2" type="ORF">VDA_000044</name>
        <name evidence="3" type="ORF">VDA_000134</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000008">
        <property type="protein sequence ID" value="EEZ38989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="ADBS01000005">
        <property type="protein sequence ID" value="EEZ39059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000015"/>
    <dbReference type="EnsemblBacteria" id="EEZ38989">
        <property type="protein sequence ID" value="EEZ38989"/>
        <property type="gene ID" value="VDA_000015"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39059">
        <property type="protein sequence ID" value="EEZ39059"/>
        <property type="gene ID" value="VDA_000044"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39118">
        <property type="protein sequence ID" value="EEZ39118"/>
        <property type="gene ID" value="VDA_000134"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0526">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014110">
        <property type="entry name" value="TraF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039555">
        <property type="entry name" value="TraF/TrbB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13728">
        <property type="entry name" value="TraF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02739">
        <property type="entry name" value="TraF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ38989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="252" mass="28216" checksum="A091A44C3DB8F1C7" modified="2010-01-19" version="1">MKPLSLAWLLIVITPLYANPNGWRWYNEPKAPIVQPKPPLPKQPHATITQTPSKPMTATEQMNWFHGYMAEVQNQAVINPTVDNVLAFMKLSQYIDGKTTDFGMTWKEALLVDPSLSYRIKHPTESLARQTQNAQIKARKEAAVKALAEQGYGLFFVYQGQDPLNQQLAPSIQAFAEQYGISLLGISDDGKILPSIKQNRLNNGKLKVPVIPALLAVNPNTQDIKPLAYGFISQEELLGRFLNVATQYQPDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z589</accession>
    <name>D0Z589_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000139</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306959.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000004.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39123">
        <property type="protein sequence ID" value="EEZ39123"/>
        <property type="gene ID" value="VDA_000139"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2224301at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="181" mass="20486" checksum="FCED6796D86BCE9A" modified="2010-01-19" version="1">MNTRSKTATKFYTSERADSSVQIGLAGREVDSESVIREGNATHRLSSLEVLQAPALRAPCAAHISRANARKAAIFKRAWSLAAQKALRFGGEKCTYFAACLKVVYCQIKLTHTESRQQYGDLMKRNNEYLKQLKGRLSHYESKTDLLHREQTIADLLPRIKSAQIRQSYYIDLIFCTGLEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5E5</accession>
    <name>D0Z5E5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative DNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_000052</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Nucleoid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the histone-like protein H-NS family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000005">
        <property type="protein sequence ID" value="EEZ39067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000052"/>
    <dbReference type="EnsemblBacteria" id="EEZ39067">
        <property type="protein sequence ID" value="EEZ39067"/>
        <property type="gene ID" value="VDA_000052"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2916">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009295">
        <property type="term" value="C:nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027444">
        <property type="entry name" value="H-NS_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037150">
        <property type="entry name" value="H-NS_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001801">
        <property type="entry name" value="Histone_HNS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027454">
        <property type="entry name" value="Histone_HNS_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00816">
        <property type="entry name" value="Histone_HNS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002096">
        <property type="entry name" value="HnS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00528">
        <property type="entry name" value="HNS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNS" evidence="7">
        <location>
            <begin position="51"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="DNA-binding region" evidence="5">
        <location>
            <begin position="76"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="44"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR002096-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ39067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="93" mass="10882" checksum="9BEEC78019EC6475" modified="2010-01-19" version="1">MVNERVQEEEQLRAENREKEEKLETYRQLLLADGIDPEELIASMSAPKAKKPTRTPRPAKYRYTDENGQEKTWTGQGRTPKFLADKDLNDYLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVI4</accession>
    <name>D0YVI4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">o-succinylbenzoate synthase</fullName>
            <shortName evidence="4">OSB synthase</shortName>
            <shortName evidence="4">OSBS</shortName>
            <ecNumber evidence="4">4.2.1.113</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">4-(2'-carboxyphenyl)-4-oxybutyric acid synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">o-succinylbenzoic acid synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">menC</name>
        <name evidence="6" type="ORF">VDA_001564</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(1R,6R)-6-hydroxy-2-succinyl-cyclohexa-2,4-diene-1-carboxylate = 2-succinylbenzoate + H2O</text>
            <dbReference type="Rhea" id="RHEA:10196"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:18325"/>
            <dbReference type="ChEBI" id="CHEBI:58689"/>
            <dbReference type="EC" id="4.2.1.113"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Quinol/quinone metabolism; 1,4-dihydroxy-2-naphthoate biosynthesis; 1,4-dihydroxy-2-naphthoate from chorismate: step 4/7.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Quinol/quinone metabolism; menaquinone biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.113" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298286.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001564"/>
    <dbReference type="EnsemblBacteria" id="EEZ40538">
        <property type="protein sequence ID" value="EEZ40538"/>
        <property type="gene ID" value="VDA_001564"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1441">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="951991at2"/>
    <dbReference type="UniPathway" id="UPA00079"/>
    <dbReference type="UniPathway" id="UPA01057">
        <property type="reaction ID" value="UER00165"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043748">
        <property type="term" value="F:O-succinylbenzoate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009234">
        <property type="term" value="P:menaquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00470">
        <property type="entry name" value="MenC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029065">
        <property type="entry name" value="Enolase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013342">
        <property type="entry name" value="Mandelate_racemase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010196">
        <property type="entry name" value="OSB_synthase_MenC1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13378">
        <property type="entry name" value="MR_MLE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00922">
        <property type="entry name" value="MR_MLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="SSF51604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="SSF54826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0474">Menaquinone biosynthesis</keyword>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MR_MLE" evidence="5">
        <location>
            <begin position="116"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="135"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="237"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="215"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="324" mass="35701" checksum="ACD375380E14098C" modified="2010-01-19" version="1">MRSAKLYQYQLPMDSGVILRNQRLVTRDGFIVELKEGERCGFGEIAPLPEFSHETLEQAQQQAEALIEQWVETGDVDLNAVSPSVAFGFSMAQLELSQALPVEGNYQVAPLCSGDPDDLVVRLNQMSGDKVAKIKVGLYEAVRDGIVANMFLESIPELKLRLDANRQWTPLKAQQFAKYVKPELRAGIAFLEEPCRNPADSLAFAQETGINIAWDETVRDDGFEVKAEPGVAAIIIKPTLVGSIDKCRQLVEQAHQQGLTAVISSSLESSLGLNQLARVAQWLTPGVIPGLDTMQLFAEQLETPWPESNLPVKALSELEIICQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVQ9</accession>
    <name>D0YVQ9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Anaerobic C4-dicarboxylate transporter DcuC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_002000</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DcuC/DcuD transporter (TC 2.A.61) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299138.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002000"/>
    <dbReference type="EnsemblBacteria" id="EEZ40968">
        <property type="protein sequence ID" value="EEZ40968"/>
        <property type="gene ID" value="VDA_002000"/>
    </dbReference>
    <dbReference type="GeneID" id="57341859"/>
    <dbReference type="eggNOG" id="COG3069">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1345750at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015556">
        <property type="term" value="F:C4-dicarboxylate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004669">
        <property type="entry name" value="C4_dicarb_anaerob_car"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018385">
        <property type="entry name" value="C4_dicarb_anaerob_car-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42002">
        <property type="entry name" value="PTHR42002"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03606">
        <property type="entry name" value="DcuC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00771">
        <property type="entry name" value="DcuC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="113"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="197"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="250"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="275"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="308"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="352"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="405"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="440"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ40968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="459" mass="49411" checksum="AB69684141F0B5C3" modified="2010-01-19" version="1">MEYIFTLFIVGLVAYSMLKKFNPQATLITAGLLLLAYASISGIAPVLAEGKTQGALFFDLWQRFTEITNTRLGKVGLTLVSIAGVSTYLNHIGASQALVKATSRPVMAVKNPYILLILVLLFVSIMYVFITGATSLSLLLMGTLYPVLRNAGVSAKTAVATIVIPTAWEYGPGQINAVIGANAINVEIMDFVVNHQTIFQALLLFTIPLVNILWQRHCDRKDGYDPTQDRGKYLATLEAQHDANDTVPKFYALLPVLPFVFLFGFSSMVMESITMTIPIAMMSTITICVVIEAIRFRSIQRAFDNFEAWLKGTGMIFASVLTLMIAAEYFSAGLTNIGAINALIDTAKSFDLGPSGIVVVFSGFILLTAFITGSGNAPVMAFIPIVPQIATNFGVNPLLPLLPILFAAGIGRTMSPVAGVIITVSGMAGLTPIDVIKRTSVPMLSSMVVVLIMAVIQYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVT3</accession>
    <name>D0YVT3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_002014</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299179.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002014"/>
    <dbReference type="EnsemblBacteria" id="EEZ40982">
        <property type="protein sequence ID" value="EEZ40982"/>
        <property type="gene ID" value="VDA_002014"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0668">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1597438at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008381">
        <property type="term" value="F:mechanosensitive ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071470">
        <property type="term" value="P:cellular response to osmotic stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030192">
        <property type="entry name" value="YbdG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30414">
        <property type="entry name" value="PTHR30414"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="29"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="107"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="146"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="172"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="410" mass="46353" checksum="0130FA72675D95F4" modified="2010-01-19" version="1">MSKQIRQAVAEGMSKLGINIQPHDNFSTIVILILCTMVAFGTYVIVRWGVLKILNAMIKRTKSQWGTILVHHQVLEKLCLIIPAVVMNLLIPLVLDQYVLLSDLIDRVLGIWLIFALIRSSYAFLDASNDIFNMNHLSKNLPVKSFVQLFKLTIFFIGFFVGISILADRSPVYFLSGLGVATGLVLLMFKDTILGFVAGIQLAANQMIQVGDWIQMDKYGANGSVDEVSLTTIKVKNFDNTVTNIPAYALVQDSFINWRQMQESGGRRIKRSILINIDTIRFLTEDDEQKLATIPFVGQYIKEKKDELNRSGNPYLVNSLTNITVFRAYLEAFLQQNTHLRKDMTFLVRELEPTAQGLPIQIYVFANDTRWAYYEGIQADIFDHVFAVLPQFGLAAFQSPAASDIREIKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW01</accession>
    <name>D0YW01_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">S-ribosylhomocysteine lyase</fullName>
            <ecNumber evidence="5">4.4.1.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">AI-2 synthesis protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">Autoinducer-2 production protein LuxS</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">VDA_001306</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-(5-deoxy-D-ribos-5-yl)-L-homocysteine = (S)-4,5-dihydroxypentane-2,3-dione + L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:17753"/>
            <dbReference type="ChEBI" id="CHEBI:29484"/>
            <dbReference type="ChEBI" id="CHEBI:58195"/>
            <dbReference type="ChEBI" id="CHEBI:58199"/>
            <dbReference type="EC" id="4.4.1.21"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the LuxS family.</text>
    </comment>
    <dbReference type="EC" id="4.4.1.21" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001306"/>
    <dbReference type="EnsemblBacteria" id="EEZ40281">
        <property type="protein sequence ID" value="EEZ40281"/>
        <property type="gene ID" value="VDA_001306"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1854">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043768">
        <property type="term" value="F:S-ribosylhomocysteine lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009372">
        <property type="term" value="P:quorum sensing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037005">
        <property type="entry name" value="LuxS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003815">
        <property type="entry name" value="S-ribosylhomocysteinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35799">
        <property type="entry name" value="PTHR35799"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02664">
        <property type="entry name" value="LuxS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="SSF63411"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0071">Autoinducer synthesis</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0673">Quorum sensing</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000297"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00015130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00030600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00031777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEZ40281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="83" mass="8956" checksum="25F2A1A207276071" modified="2010-01-19" version="1">MSLIGEPQETVVAQAWLDAMQDVLLVDSQDKIPELNEYQCGTYAMHSLAEAQAIAQSIITAGVGVNQNDDLALPAEMLVQLKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW28</accession>
    <name>D0YW28_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001291</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297807.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40266">
        <property type="protein sequence ID" value="EEZ40266"/>
        <property type="gene ID" value="VDA_001291"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502ZBDX">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1015114at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="388" mass="42979" checksum="74DE703256832F43" modified="2010-01-19" version="1">MSELNLTGCLISSSDKTVKSLVTYLPAIELENYFYINRIPPQLEVFFDAAKNKTNLKRVSDIQADLEKELSQKMIGTPISLTVVLDGKPTLSLTDGAAKVSYDRDSSFIVGEILILTAVLKSLGIKTPLFSSRLSASEIKKKSAFRQILSVQSVVLTVIFDDESGIDEEQVKELFFKFNRQHSGMHLSQFSQTNDAFPLRPYVLKLAVELSLDSFGGVSDKSKHVKMSESYLTTEYILFKFLVGAVAGAHVQEICKMSDEVTTSSGKTVSECLSNGNFDYIKAFLSSWLTPLEQGGKVERAGFRLSAQIWQALALVIHRLISDGASVQEVSHAGLILGQLDYCKKASHWGDCEVMALDSNGRLYKNAANSTREFRNGLADYFYRVVSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW52</accession>
    <name>D0YW52_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_001334</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297871.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001334"/>
    <dbReference type="EnsemblBacteria" id="EEZ40309">
        <property type="protein sequence ID" value="EEZ40309"/>
        <property type="gene ID" value="VDA_001334"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1275">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1600064at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004695">
        <property type="entry name" value="SLAC1/Mae1/Ssu1/TehA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038665">
        <property type="entry name" value="Voltage-dep_anion_channel_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03595">
        <property type="entry name" value="SLAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="73"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="103"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="133"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="162"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="194"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="218"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="251"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="285"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="328" mass="35674" checksum="C8E11F23E9A0BBFD" modified="2010-01-19" version="1">MIQATKRKVAGAPTPMAGLALGIGSLGWCWENGASLHGAGQIIGASIAAVLLAILVVKFVLHPNLLLGDLRHHVVGSVVPTFAMALMVVSKAVGMYFPVLAQAIWLFAVILHLVFLTLFTYHRVIEFELHHMVPSWFVPPVGIIVADVAFPGGALRPLAEGLLIFGMVAYAIMLPIMIYRLIFSHEVPDAAKPTIAILAAPASLSLAGYLTVCQTPSPVIIALLGGIAVLMTFIIYLAFFRLMRLEFSPGYAAFTFPMVIGSTALFKTAAWMTHYGFAEQYVNQVHTLATLELYVATVVVGYVALRYKMFYRPLSRLFTRCPNSPQNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWI7</accession>
    <name>D0YWI7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Pyrroline-5-carboxylate reductase</fullName>
            <shortName evidence="3">P5C reductase</shortName>
            <shortName evidence="3">P5CR</shortName>
            <ecNumber evidence="3 4">1.5.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">PCA reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">proC</name>
        <name evidence="7" type="ORF">VDA_001229</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>L-proline + NAD(+) = 1-pyrroline-5-carboxylate + 2 H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:14105"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15893"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="EC" id="1.5.1.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 4">
            <text>L-proline + NADP(+) = 1-pyrroline-5-carboxylate + 2 H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:14109"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15893"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="EC" id="1.5.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 4">Amino-acid biosynthesis; L-proline biosynthesis; L-proline from L-glutamate 5-semialdehyde: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 4">Belongs to the pyrroline-5-carboxylate reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.2" evidence="3 4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297684.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001229"/>
    <dbReference type="EnsemblBacteria" id="EEZ40207">
        <property type="protein sequence ID" value="EEZ40207"/>
        <property type="gene ID" value="VDA_001229"/>
    </dbReference>
    <dbReference type="GeneID" id="57339893"/>
    <dbReference type="eggNOG" id="COG0345">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1349288at2"/>
    <dbReference type="UniPathway" id="UPA00098">
        <property type="reaction ID" value="UER00361"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004735">
        <property type="term" value="F:pyrroline-5-carboxylate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01925">
        <property type="entry name" value="P5C_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028939">
        <property type="entry name" value="P5C_Rdtase_cat_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029036">
        <property type="entry name" value="P5CR_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000304">
        <property type="entry name" value="Pyrroline-COOH_reductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11645">
        <property type="entry name" value="PTHR11645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03807">
        <property type="entry name" value="F420_oxidored"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14748">
        <property type="entry name" value="P5CR_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000193">
        <property type="entry name" value="Pyrrol-5-carb_rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00112">
        <property type="entry name" value="proC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00521">
        <property type="entry name" value="P5CR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4" id="KW-0521">NADP</keyword>
    <keyword evidence="2 3 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 4" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F420_oxidored" evidence="5">
        <location>
            <begin position="6"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="P5CR_dimer" evidence="6">
        <location>
            <begin position="163"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF14748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="272" mass="28580" checksum="A856FD84635FC4A4" modified="2010-01-19" version="1">MTQRSIAFIGAGNMAKSIIAGLVNSGYDPKKITVTAPSATRRQPLAEEYGVQTSSDNFASAAAADVVVLAVKPQLMAEVCKPLQKVDFSNKLVISIAAGVSSARLNEMLACQLNLVRVMPNTPALIGQGMSGLFAVDGLAQADKAFAEQLLTAVGKVCWVSQEADINGVIAAAGSAPAYFFLFMEAMEQEAIRQGFDPETARLLVQQSALGAAHMVEANPATSLATLREQVTSKGGTTAEAIATFNQHQLSDTVAQAMQAAVARAQEMEQLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWR0</accession>
    <name>D0YWR0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001457</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298093.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001457"/>
    <dbReference type="EnsemblBacteria" id="EEZ40431">
        <property type="protein sequence ID" value="EEZ40431"/>
        <property type="gene ID" value="VDA_001457"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3735">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1991552at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002816">
        <property type="entry name" value="TraB/PrgY/GumN_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01963">
        <property type="entry name" value="TraB_PrgY_gumN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018636" evidence="1">
        <location>
            <begin position="20"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="281" mass="31593" checksum="9B5BD3C194974801" modified="2010-01-19" version="1">MRKYIYALLLPFLSFSALSAPLVWQAQKGDVNFYFLGSIHAGKKTFYPLPSEFMEHWSSANALIVEANILSSTEVKPDLSGPTTKQQLTPKQQEQLKVISDTLSLPYSHLLTMPPWLSAINLQMALTNQLGLDPQQGVDYQLLLKAQHDKLPIKELEGVEQQFALLANLPEHGTPMLQETVTNWEQLKQDMADLITAWQTGDQTKLNQLFTNSQFDDQSDEQLIFGRNKQWAHILSDPQQYPAGNYLVVVGAFHLLGDKGVPALLAEEGFIVKRVSEFSPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWR5</accession>
    <name>D0YWR5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Smr domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001456</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298091.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40430">
        <property type="protein sequence ID" value="EEZ40430"/>
        <property type="gene ID" value="VDA_001456"/>
    </dbReference>
    <dbReference type="GeneID" id="57339581"/>
    <dbReference type="eggNOG" id="COG2840">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1888882at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002625">
        <property type="entry name" value="Smr_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036063">
        <property type="entry name" value="Smr_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01713">
        <property type="entry name" value="Smr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00463">
        <property type="entry name" value="SMR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160443">
        <property type="entry name" value="SSF160443"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50828">
        <property type="entry name" value="SMR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Smr" evidence="2">
        <location>
            <begin position="95"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="88"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="193" mass="22247" checksum="997B890916178ECB" modified="2010-01-19" version="1">MSDNNELDLFREMMADVSPIKQDTVEVTNKFNVTDAQLARQLAAQTLSDSDPEYLSIDYAKMVKPDDMLEFKRDGVQEGVIRKLRLGKYEIQARLDLHRKTLKEAREEVLKFLKQCQRLDIRSVLIVHGKGERSNPPALMKSYLATWLEQISDVMGYHSALRQHGGCGAVYVMLKKSPEKKLDNRERHLARRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX67</accession>
    <name>D0YX67_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Iron-containing alcohol dehydrogenase</fullName>
            <ecNumber evidence="3">1.1.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001832</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.1" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298784.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001832"/>
    <dbReference type="EnsemblBacteria" id="EEZ40800">
        <property type="protein sequence ID" value="EEZ40800"/>
        <property type="gene ID" value="VDA_001832"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1454">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1456634at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004022">
        <property type="term" value="F:alcohol dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001670">
        <property type="entry name" value="ADH_Fe/GldA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039697">
        <property type="entry name" value="Alcohol_dehydrogenase_Fe"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11496">
        <property type="entry name" value="PTHR11496"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00465">
        <property type="entry name" value="Fe-ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe-ADH" evidence="2">
        <location>
            <begin position="8"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="405" mass="43870" checksum="297EB8F35DB999ED" modified="2010-01-19" version="1">MFQFMTSTRIVFGEHALVESLSSLNQFGYSVLLVTGQDSSRAQPLIEYFQQQSMRFQQVSVLGEPLIAMVEEMAAMARQFRPDMVIAIGGGSVLDTGKALAALIPNQGSVYDYAEVVGRNLPLQSKPIPFIAIPTTAGTGSEVTRNAVLKSAQENIKVSLRSPEMLPDLAIVDPTLTYGMSPQLTACCGMDAFTHLMEAYVCGEPNALTDMICEEGLRRIATAIIPACEQDDPEARSDMAFASMLGGMALTNAKLGAAHGLAAALGGRLNAPHGVITARLAPYVMEENVAIAKEQNRKDILGRYKKLAEILTIKPCAEIEEGIDWVKSILTRLEIPLVGQYGLCATMFDEVAKDALLSNSIKGNPIPLSQERLESILEHICQSCSCHLNTNDDSIEQDEPMVETQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXA8</accession>
    <name>D0YXA8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ATP-dependent Clp protease ATP-binding subunit ClpA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_001648</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the ClpA/ClpB family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298439.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001648"/>
    <dbReference type="EnsemblBacteria" id="EEZ40621">
        <property type="protein sequence ID" value="EEZ40621"/>
        <property type="gene ID" value="VDA_001648"/>
    </dbReference>
    <dbReference type="GeneID" id="57342269"/>
    <dbReference type="eggNOG" id="COG0542">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="44062at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043335">
        <property type="term" value="P:protein unfolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036628">
        <property type="entry name" value="Clp_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004176">
        <property type="entry name" value="Clp_R_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013461">
        <property type="entry name" value="ClpA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018368">
        <property type="entry name" value="ClpA/B_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028299">
        <property type="entry name" value="ClpA/B_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041546">
        <property type="entry name" value="ClpA/ClpB_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17871">
        <property type="entry name" value="AAA_lid_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02861">
        <property type="entry name" value="Clp_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81923">
        <property type="entry name" value="SSF81923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02639">
        <property type="entry name" value="ClpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51903">
        <property type="entry name" value="CLP_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00870">
        <property type="entry name" value="CLPAB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00871">
        <property type="entry name" value="CLPAB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0143">Chaperone</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Clp R" evidence="9">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="143"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="143"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ40621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="754" mass="83632" checksum="88A59C26ADEE5308" modified="2010-01-19" version="1">MLNKELEASLNGAFARAREKRHEFMTVEHLLLALIDNAAAQEALLACRADLDQLRKELHSFIDQTTPLIPEDDTGRETQPTLSFQRVLQRAVFHVQSSGRNEVTGANVLVAIFSEQESHAAYLLKKSDITRLDVVNFISHGTVKDSVNDNSPSESANQDETRIEQSSEDKLENFATNLNNLAKAGGIDPLIGRDQELERTIQVLCRRRKNNPLLVGEAGVGKTAIAEGLAWRIVEGQVPDVIKDCVIYSLDIGSLLAGTKYRGDFEKRFKGILKQLEKEDHAIMFIDEIHTIIGAGAASGGQVDAANLIKPLLSSGKLRCMGSTTYQEYSNIFEKERALSRRFQKIDVVEPSIDDTTKILMGLKPKYEAHHEVRFTNKAIRAAVELSAKYINERHLPDKAIDVIDEAGARCRLAPASRRKKTINVSDIEAMIAKMARIPEKSVSSSDRDVLQSLDSKLKMLVFGQDDAIDVLTEAIKLSRAGLGADNKPVGSFLFAGPTGVGKTEVTVQLARTLGIDLLRFDMSEYMERHTVSRLIGAPPGYVGYDQGGLLTDAVIKNPHSVVLLDEIEKAHPDVFNLLLQVMDNGTLTDNNGRKADFRNVILVMTTNAGVTETTRKSIGLIQQDHSHDAMAEIKRVFTPEFRNRLDGIIWFNHLEKEVISQVVDKFIVELQAQLDARGVSMEVTDRAREWMADKGYDKAMGARPMARVIQDSLKKPLANELLFGELVNGGSVRVDLINDQLDFQFSSEMEAAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXC7</accession>
    <name>D0YXC7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Deoxycytidine triphosphate deaminase</fullName>
            <ecNumber evidence="5">3.5.4.13</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001667</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.5.4.13" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001667"/>
    <dbReference type="EnsemblBacteria" id="EEZ40640">
        <property type="protein sequence ID" value="EEZ40640"/>
        <property type="gene ID" value="VDA_001667"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0717">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008829">
        <property type="term" value="F:dCTP deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006229">
        <property type="term" value="P:dUTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07557">
        <property type="entry name" value="trimeric_dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011962">
        <property type="entry name" value="dCTP_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029054">
        <property type="entry name" value="dUTPase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036157">
        <property type="entry name" value="dUTPase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033704">
        <property type="entry name" value="dUTPase_trimeric"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00692">
        <property type="entry name" value="dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51283">
        <property type="entry name" value="SSF51283"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02274">
        <property type="entry name" value="dCTP_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="dUTPase" evidence="4">
        <location>
            <begin position="49"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="141"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="167" mass="18381" checksum="B9B46B2C7290BF43" modified="2010-01-19" version="1">MTVDVSLGNKFRIFNDHGAPYIDLSGRKEEVSAQLDKVMSDEIEVAEDEAFFLHPGQLALAVTHESVTLPANIVGWLDGRSSLARLGLMVHVTAHRIDPGWSGRIVLEFYNSGRLPLALRPHMPIGALSFETLSGPAEKPYNKRADAKYKNQQGAVASRINEDDKEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXE3</accession>
    <name>D0YXE3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001622</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298391.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40595">
        <property type="protein sequence ID" value="EEZ40595"/>
        <property type="gene ID" value="VDA_001622"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018703" evidence="1">
        <location>
            <begin position="20"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="144" mass="16023" checksum="98C33F4DBFB194EF" modified="2010-01-19" version="1">MKKLLIVALLVVSSTSVVADDRIPSVVGEWQDCGPLNVVAVQAEHDDVLIQLENETDGWQVWKRIGVTQDDSVYDGLIPRQSRSQGADIEGNLTFNTSSHIMQFQSLAEKALLNDKQVIVRFEGDEVCHADNYNSNAVMIRLIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXF8</accession>
    <name>D0YXF8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative two-component response regulator and GGDEF family protein YeaJ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001637</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298420.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001637"/>
    <dbReference type="EnsemblBacteria" id="EEZ40610">
        <property type="protein sequence ID" value="EEZ40610"/>
        <property type="gene ID" value="VDA_001637"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3706">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="313"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="2">
        <location>
            <begin position="384"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="517" mass="60117" checksum="2688D40533EB7290" modified="2010-01-19" version="1">MSENKHLLANENSFYEHHFLFKSKTWHNIFVVGINSLLIIGLIAFNLYRQIDANKNYIDSNLKLVKSSMMTLAYRNDRYAQTVTKTLKDVSIMSQPGLVSINTYPSMNEFGFNRGIYPDNLLNGSLIGVGKPSEAIYHDTNLFQILDDLWAEQHRRNITYNYYYISHQHRYFYLSSKYSLNDFNMTKDFFTTDFYSQQRSDLQQESTLKKGFYFTPPYRDFFTHDMVITIKSPVFSAKDIIIGDVGVDIPVKSLMRAITLPNDFKQYLNIYLYDDIKKQTITLYDGKRSYLPWINMNRQINDTLSIHAEISSWYILYSSIQDISLIIVLIIALNYMYSLLKMHKAQKNEYKIEAYTDSLTGLYNRRIIKSSVMPLLQEAKDTHSPVSFIIIDANDFKIINDNYGHDVGDMALKHIANQIFALSRSSDICIRLGGDEFCIVLPNTTIGQAHSLSRRLELAVYGIKFYSQKITTTITTSCVQYDGEETLEETFARADKILYNNKLHKKERLKKLKEQLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXG7</accession>
    <name>D0YXG7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">D-lactate dehydrogenase</fullName>
            <ecNumber evidence="7">1.1.1.28</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_001702</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.28" evidence="7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298543.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001702"/>
    <dbReference type="EnsemblBacteria" id="EEZ40673">
        <property type="protein sequence ID" value="EEZ40673"/>
        <property type="gene ID" value="VDA_001702"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1052">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1638924at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008720">
        <property type="term" value="F:D-lactate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029753">
        <property type="entry name" value="D-isomer_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029752">
        <property type="entry name" value="D-isomer_DH_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00065">
        <property type="entry name" value="D_2_HYDROXYACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00670">
        <property type="entry name" value="D_2_HYDROXYACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00671">
        <property type="entry name" value="D_2_HYDROXYACID_DH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2 4 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2-Hacid_dh" evidence="5">
        <location>
            <begin position="4"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="2-Hacid_dh_C" evidence="6">
        <location>
            <begin position="110"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="331" mass="37188" checksum="670B3A52F99EE5F5" modified="2010-01-19" version="1">MKVAVFSTKNYDQKSFEHINKHYHHELTYYDFRLTRHTAKMAHGFDAVCAFVNDDLNHHVIAQLAQYGVKIIAMRCAGFDKVDLEAAKVFGIQVVRVPAYSPEAVAEHTLGLMLSLNRRIHRAYQRTRDANFSLEGLTGFNFHGKTVGVIGTGKIGIATMRILNGLGMNILAFDPFENPAAIELGAKYTTLDDIYQQADVITLHCPMTPENHHMLNEESFNKMKDGVMIINTSRGGLLNSVDAIEALKHRKIGSLGVDVYENEQDLFFQDKSNDVIQDDVFRRLSSCHNVLFTGHQAFLTEEALANIADTTLNNLKLFKEQKSSGNELIEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXJ2</accession>
    <name>D0YXJ2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001706</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001706"/>
    <dbReference type="EnsemblBacteria" id="EEZ40677">
        <property type="protein sequence ID" value="EEZ40677"/>
        <property type="gene ID" value="VDA_001706"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4191">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004673">
        <property type="term" value="F:protein histidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="3">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="4">
        <location>
            <begin position="274"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="442" mass="48903" checksum="5A6D8F31D847C937" modified="2010-01-19" version="1">MHQPKALQRIIDVYFRESARTQAVSTGTQVLQQNGYNDRLYWVKKGELSGYLLNEATGLTAKVFRVEQGMFFGVHSFFAQTLMASTTVIAEKDSEIAWIDASTKAVEPELYGSLVEQFMPVMVHELAQRQMLTGLQAIEKEKALQKLYASEQLTTLGQLAAGIAHELNNAVGVLSSKTESLQQALCQQLEVQRPQAIAFIEQGIESGQQSGSADVRVRSKALMAQYPSLSREQAKLLARAVPNGDITPDWLNDLDMALQYWDIGRDLHDMKIAAKHAASIVRSVKQLGGSDQDRQTDVDVNDTIHKSLALLQSNLRRVNVVTHSATLPTITASTTELVQVWVNIIKNACDALENTEEPTIEIITRHSKNRLLITISNNGPMIDEATRRKIFQPNFTTKKGGLSFGLGLGLSIVQRIVDSYGGTVALKSDTERTKFRIKLPIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXR3</accession>
    <name>D0YXR3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Paraquat-inducible protein A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_002076</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PqiA family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299360.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002076"/>
    <dbReference type="EnsemblBacteria" id="EEZ41044">
        <property type="protein sequence ID" value="EEZ41044"/>
        <property type="gene ID" value="VDA_002076"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2995">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="836803at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007498">
        <property type="entry name" value="PqiA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005219">
        <property type="entry name" value="PqiA-like_Ent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04403">
        <property type="entry name" value="PqiA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00155">
        <property type="entry name" value="pqiA_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="46"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="91"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="139"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="163"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="241"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="288"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="335"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="365"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ41044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="397" mass="44583" checksum="E0A1303A18AA4932" modified="2010-01-19" version="1">MSTARLCPGCDLLIQPKDANLGQSAYCPRCQTRLYRGGVRQFGGDLALAVACLILFVPAHIFPLITIRLFGQMIPATLPSGTITLAGNFPGVAALILFCSSIAPFLVMSSVITTQLGLHFRRFKLFKRSLWLLEHLKHWAMFDVFLVSLAIACFKVQDHADIYVGSGLFSLVILQFLMLALLTKISVRRYWDAWQPEKEHLNTDLEVHCHTCHLTQKQQAYCRRCGSELHHRDPNSIQKTWAYLISASVFIFPANLYPISIFFNNGKQLEDTIFSGVATLVKTNMSGIAAIIFIASIVVPVAKILGLAYILLCIQFKRQGSFLTRMKMYRIIQWIGKWSMMDLFVISIMVTLIDRGQLLDFTPGPGAIAFAVVVVLTMLAAESLDSRLIWDNYEQPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXY3</accession>
    <name>D0YXY3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">IcmF-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_002146</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299538.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002146"/>
    <dbReference type="EnsemblBacteria" id="EEZ41114">
        <property type="protein sequence ID" value="EEZ41114"/>
        <property type="gene ID" value="VDA_002146"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3523">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="393769at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009612">
        <property type="entry name" value="IcmF-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025743">
        <property type="entry name" value="IcmF-related_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010623">
        <property type="entry name" value="IcmF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017731">
        <property type="entry name" value="TssM1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06761">
        <property type="entry name" value="IcmF-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14331">
        <property type="entry name" value="IcmF-related_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06744">
        <property type="entry name" value="IcmF_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03348">
        <property type="entry name" value="VI_IcmF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="453"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="domain" description="IcmF-related_N" evidence="4">
        <location>
            <begin position="202"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="domain" description="IcmF-related" evidence="3">
        <location>
            <begin position="510"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="domain" description="IcmF_C" evidence="2">
        <location>
            <begin position="1054"/>
            <end position="1160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF14331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="1181" mass="135429" checksum="53FEDBF82D0AFC3C" modified="2010-01-19" version="1">MWNYIRAIFNRIAPTFKASVPILLIATFILLNVAIWWAGPWLEIDGKTPLASTMARAVTSIIFSLCCFTVWGVFQWRRLQQINDAKAREEKLREDPIKRLEERQELELNQVMTEMKDSLNKRNYLYALPWYLVLGLENAGKTSLINRSGQNFVFSSVMRASGKKSENPFSFDWWIGDDSVLIDPDGELLTQRQNEADKDGEMERRLWLHFVKWLEKTRSRRPLNGVILTLDLSHLATVTVAERQAYANLLRARLRELMETLSTRMPVYIALTKLDLLYGFEPFFRQYTRAQREEVMGFTFSLNSVTDLDSWLAEFDRDYSQFIERINDSLPQALRHAVDSEERSAIYSFTRQIAGMHDVLKAFFTDALSSDQFSTSALVRGAYFMSVYQQGVPENAFVNAASQRYGLADSVQSAQHAQNSTTYFVKRLFNEIIYPEAGIASDNFRVAKQKKKILMLSVVACSIASVLLIGSWHRYYMKNVEQENAVLAQVNQYKSEYSDSKIMRSEQEILEPLNTIREATLEFGFFRDKPKYVSDMGLYQGHVIGPKVEETYLSLLEFRYLPSLMKQLAVDLSQANSEEEELETLRVFRMLTDKGGRQDKVVTNYFAQVWQQAFPNNVKTQEQLMEHLNYALMHTDLQGLRRDDNQDAIRVMRPYDHLIQQTQEALGSVSIAERVYRNLKQSANAALGAPLDLKTAVGPVFDLVFEQRVSNGQALDIPQLLTQKGFNSYFLPQSESVSELALVDSWVLGQTTVAQFSLEDKQVLRQKIRDLYVADYTNTWRSAINDVDVKYFADINEAVSVFSQFMGPQQPMNRLLNTVEKNTQLFPNLPQDDKARLALMESIQYKVAAMIALPFADIDGLLAQKDQQPAYISEVMSAMQQVYSYLKAIQDAPDMGKAALEATKERVELKNSDPIYTLQRMASSLPKPLDSMMEKLADESWYAVKQEAIKYLEVRWQHDVYQEYQAKLATRYPFNPRASKDVSLKDFESFFAPDGTLSRFYNDQLKMFIDENISMSVNGQQNAFLRSDVLKQFTNAKKIQEAFFNRKGILDVEFSLEPIELSSNQRRSVINVDGQYVEYSHGPHRSIELVWPNTLREGAISKLSLVPSKVNKSPRGITIQGPWAFFRLLDRGAVVSSSSTSVDYQFSINGGEVTYRLTSEADANPFTSALFRNFKLTRTLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY33</accession>
    <name>D0YY33_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002196</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299630.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41164">
        <property type="protein sequence ID" value="EEZ41164"/>
        <property type="gene ID" value="VDA_002196"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2178722at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="277" mass="31570" checksum="B4D8D3799172AC50" modified="2010-01-19" version="1">MKISKTRYQIRKEIQQLSRIDSSKISIPYLTSKVDSLLKGMWTPWFGGPFYEVWRARSGFYNNISELWCPPAECVLKRGRMNDINESIFYSCFGHNANLGSLEEIRTEVGDIVTQLCCKLDPEDKILKVLSLGHADIWMKEKAPDYMKQYFIDAEARYKADCGTDEQYSRSLVLKNWVNDTFIEKVNDGQECKYAHSIAISKAFFSGFDCEGILYPSVASNAKAVNLVLKPRVAEAYLKPNYARVVEIVSKSSQGFGLKIKNESKSISSDGTINWSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY70</accession>
    <name>D0YY70_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative cytochrome oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002233</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299703.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002233"/>
    <dbReference type="EnsemblBacteria" id="EEZ41201">
        <property type="protein sequence ID" value="EEZ41201"/>
        <property type="gene ID" value="VDA_002233"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0558">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1232102at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016780">
        <property type="term" value="F:phosphotransferase activity, for other substituted phosphate groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="24"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="109"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="173"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="204" mass="22484" checksum="DA2BE9863B7D54B1" modified="2010-01-19" version="1">MLDRYAIKIIKLPLKTLAALPDKLGISANQVTITGFIIGLFTLPALTFQRYDLALIFIVINRLLDGLDGAIARRQGITDCGGFLDITLDFIFYSLVPFGFVLADPNNNAIAGAFLIYSFIGTGSSFLAFAIMAGKRNIESPVYKQKSLYYIGGLTEGTETIACFVLFCLFPSYFSIIAWIFGALCWVTTATRIWAGYQTLKQQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY75</accession>
    <name>D0YY75_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Arginine ABC transporter permease protein ArtQ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_002238</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299714.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002238"/>
    <dbReference type="EnsemblBacteria" id="EEZ41206">
        <property type="protein sequence ID" value="EEZ41206"/>
        <property type="gene ID" value="VDA_002238"/>
    </dbReference>
    <dbReference type="GeneID" id="57341608"/>
    <dbReference type="eggNOG" id="COG4215">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1523519at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071705">
        <property type="term" value="P:nitrogen compound transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010065">
        <property type="entry name" value="AA_ABC_transptr_permease_3TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01726">
        <property type="entry name" value="HEQRo_perm_3TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="59"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="87"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="14"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="242" mass="26362" checksum="443C937F716F4E01" modified="2010-01-19" version="1">MGLTGYSLSLLEASWMTIQLAFTSLAVGLVLAVIFAAGEMSRHKLLAWTTTGWVTLLRGLPEILVVLFIFFGSSQILFYITGDYIEVSPFLSGVIALSLIFSAYASQTIRGALKAVSKGQREAASALGLSSGRTFFKIILPQTVRHALPGLTNQWLVLLKDTALVSLIGVTDLLKQAQLTSAATHESFTWYATAAAIYLVITLLTQQLIKVVEKKYQIQDTQSYDIKSKKKISKKPIAQGVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY98</accession>
    <name>D0YY98_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glyceraldehyde-3-phosphate dehydrogenase</fullName>
            <ecNumber evidence="8">1.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_002261</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.-" evidence="8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299747.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002261"/>
    <dbReference type="EnsemblBacteria" id="EEZ41229">
        <property type="protein sequence ID" value="EEZ41229"/>
        <property type="gene ID" value="VDA_002261"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0057">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="944149at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020831">
        <property type="entry name" value="GlycerAld/Erythrose_P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020830">
        <property type="entry name" value="GlycerAld_3-P_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020829">
        <property type="entry name" value="GlycerAld_3-P_DH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020828">
        <property type="entry name" value="GlycerAld_3-P_DH_NAD(P)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006424">
        <property type="entry name" value="Glyceraldehyde-3-P_DH_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02800">
        <property type="entry name" value="Gp_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00044">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000149">
        <property type="entry name" value="GAP_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00078">
        <property type="entry name" value="G3PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00846">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01534">
        <property type="entry name" value="GAPDH-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00071">
        <property type="entry name" value="GAPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 8 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gp_dh_N" evidence="9">
        <location>
            <begin position="3"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Glyceraldehyde 3-phosphate binding" evidence="4">
        <location>
            <begin position="151"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Glyceraldehyde 3-phosphate binding" evidence="4">
        <location>
            <begin position="210"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="152"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="12"/>
            <end position="13"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="315"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="site" description="Activates thiol group during catalysis" evidence="6">
        <location>
            <position position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ41229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="337" mass="36772" checksum="3F3234F720C97939" modified="2010-01-19" version="1">MTIKVGINGFGRIGRLTMRAAFDWPEIEVVQINDVAGDTATLAHLLEFDSVQGRWNKTVAVDGQTMLINGKAITCSQEKEITAVDWSGCDVVLEATGVHRNKALLDQYIAQGVKRVVVSAPVKHPDVQNIVVGVNDNLFEPEKHTIVTAASCTTNCIAPIVKVINEHFTIEQSSFTTIHDLTNTQTILDAPHKDLRRARACGMSLIPTTTGSAKAIIDIFPELDGKIDGHAVRVPLANASMTDIIFNLAEETSVDEINTLLQQAADNELSGILGFEARPLVSIDYKGEQRSTVVDALSTMVVNGRMVKIYAWYDNEMGYATRTAELVRKVGLADKIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYE2</accession>
    <name>D0YYE2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002305</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299828.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002305"/>
    <dbReference type="EnsemblBacteria" id="EEZ41273">
        <property type="protein sequence ID" value="EEZ41273"/>
        <property type="gene ID" value="VDA_002305"/>
    </dbReference>
    <dbReference type="GeneID" id="57341511"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1661500at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="2"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="300" mass="33423" checksum="5E5504D6F1709B4F" modified="2010-01-19" version="1">MPQIDDLVLFTQVIEHGSFSKVAELNSITKSVVSKRISKLESELGIQLIYRTTRKLTITEAGEVLYHRAKSISQVAQSAFDAVTGYSEALSGTIKMSVPTISGELLLAESVSEFCKKHPGLTVNMSLDNHFVDLVAGNFDLVIRTGYLEDSSLIARHIFNSRWVLCASPEYLAQHGIPNTPKDLLRHNCLGYNHQASGSFDWQFIRNDEVYTLRVAGNFSSDNAAALKKVALAGNGIAYLPTCLVYDELHNEKLVEILSEHAGKVVGIYAVYPYTKKPAKRIQALIEHIRESYMEIKEKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYI7</accession>
    <name>D0YYI7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299932.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002350"/>
    <dbReference type="EnsemblBacteria" id="EEZ41318">
        <property type="protein sequence ID" value="EEZ41318"/>
        <property type="gene ID" value="VDA_002350"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3391">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="117633at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019882" evidence="1">
        <location>
            <begin position="21"/>
            <end position="990"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="990" mass="112883" checksum="8B9F892A08DCF31E" modified="2010-01-19" version="1">MKIKTITAIIGSLFASTALANSAEQEYFKSVYQDAYQQVSSKLETLRQQANNPNNVIVENNQRYLEVNGIKYRLNSDNYILFDFPRPFTDESSFRNIFNSLSDDWELTWYDLGVVMVNKHFGNYEYGNGCLMEYYPGGTTFNNEFTRVVLETSSCSFNDFSTQLEYFEHDKTITAQDLGLESLSITAVERYKDRLYVTQDTTPGTVFIIDVNTKAVLGTITGIETPTGFADYKRINELYIRDNLLYVASLSSNRVDIFDLDNHHQHVTTIGTGSWSGSNGILHAQSVVANNEYVIVSDASNRISVYRQSEVTPENNLKMSRYGFLNFEGKYTHRKVQMHILDHYLLVLTANKNYYIYDLNKIDDAVTSGTYLDPEMRVDQRIQKIDKEGDKLIVNFADRIEWHSVNDVIAANFSFDKPLRTIKSLNGYSITALNDLHFSQGELVTASAKGLSIDNLKVNDVAFVADQSVETKNIHFDVLMPSSVTEILTNDEPHSVLINRELRSVNINSLVKTQLLDNETVQITNYAAKELKDIAVELKLNGINKWFVLGQFDRLPAYAQITLPLSAFGEQFNSVDGDGYFDLAPLFASSMNITKAFEARFDSKTDTFAQMLARLKPSWEIRFAANSEGKWRAMNGLYAREWLIIMTNFAYMVSSNEFKHVWFNFKDIMGYDMHGTAGAVNEPNGFFTAQDYDHYYHSLLKRPYVNVGITAMGGGLGGQGITGVDTWMFYTHYYGTWGIIAHEFGHGFDGMTTYGHHTSFANGGNGWQPLMTMLANYHIRKGDLPYMDDNINGFYKEENNAYHYSGIDLNKRKYRADTHMYLLDKYFMTFSSMPKGWVENGPEFNLATVNGLNNQERMLMAKYPMGDQSPYLCRFTFSDGEQYFGYVDQADNQNFCNAGSDISYRQANGEQVALRSQVNAFEWLSLYNPSLKDQAVTNAEGQSLCQMNYQEFYGTGFVNGSGQCVQKPNVYWSNGNRWVFSSRWSEMKFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYI8</accession>
    <name>D0YYI8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Chitodextrinase</fullName>
            <ecNumber evidence="8">3.2.1.14</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_002351</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.14" evidence="8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299933.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002351"/>
    <dbReference type="EnsemblBacteria" id="EEZ41319">
        <property type="protein sequence ID" value="EEZ41319"/>
        <property type="gene ID" value="VDA_002351"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3325">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3979">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1081028at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004568">
        <property type="term" value="F:chitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003610">
        <property type="entry name" value="CBM_fam5/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036573">
        <property type="entry name" value="CBM_sf_5/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009470">
        <property type="entry name" value="Chi_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06483">
        <property type="entry name" value="ChiC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00495">
        <property type="entry name" value="ChtBD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51055">
        <property type="entry name" value="SSF51055"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54556">
        <property type="entry name" value="SSF54556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3 5 8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018730" evidence="6">
        <location>
            <begin position="26"/>
            <end position="1172"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="7">
        <location>
            <begin position="466"/>
            <end position="928"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ41319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="1172" mass="127960" checksum="61FE2183CB5F7A53" modified="2010-01-19" version="1">MKKTIKFIPTLLAASIGLALPSAQAAINGQVSIVGSESQYWNTYQVTLTNQGNQAIDLRGAKIQFNSNLSISSPSWSANTVSYPIMNFTSVSQGEIFANTLALSFDQGSWVKSQLPAGETIQLTLGVSGVLDTTLVQSSMTVITEDDGNNEPSLELVLTSPTVGSEFTTGDIVTIAANVTAENTTATQVTFYVDGQEIGQKTQAPYQTLWTATDTGSHKITAKVSDANGLTAEQSAIITVKAQTTPPVEPTAPVIAITAPQQGTKVEQGETITITTQASDKDDDIRYVELWVNDAKVATNTQAPYSFSWTAEKSGIHTLTVKVIDDTQLSHSDSVTIEAVEKPVEPQAPEISLVNPRPGQTVFLGKTITISANASDANNDLVSVDFFINGQAVGSIAEAPFAVQWTPVVVGDYAIEAIAYDAAGHQTRTTKTVVKAQEMGTGNLSCDIKQIYREDGTECMGDDHPRRIIGYYTSWRTGKNGLPSYLAHDLPWDKLTHINYAFVGIDKEFNLTVDDSATKMTWDGVAGAEMDPSLPYQGHFNLLNKFKKQYPDVKTLISVGGWAETTNFYPMTTNLESCSINMDGIDKFAQSAVKFIRQYGFDGVDIDYEYPTSMKDSGNPIDFELSNKCRDQLWTNYMVMMKQLRTELDKAGKEDGRRYMLTIASPSSGYLLRGMEDFGMQDVLDYVNIMSYDLHGTWNEFVGPQAALFDDGKDAELAKWGVYTTEQYQGIGYLNQAWAHHYFRGAFKPSQINMGIPYYTRGWQGVTGGTEKGLWGKAVEPNQSSCPEGTTVCGWGAEGIDNIWHDSDKQGNEIKAGVVPMWHAMNLMHADKLGMQGSMPSYGPAWGLDPNNAKDKVEGSYERVWNHELQTAWLWNDLKKVFLSIEDKESLKPKLDYIVDNGLGGMMVWEMAGDYRFDNEKNEYVMGTDMTDYAHDVFTQAPPMEIKHNDLPAPNSVIDVTVSTTEWPAGDSNYPINPKLVFKNNSDVAIPGGTTIEFLMATATGDIVKDWSGANIKIVESGHTGHNFSVDGEKKMFHKLALTLRTSESIPAGGEYVVSLVYYTPVSGVANGVRFIVGDEVIGLKKDFPSLPEFEGSIDNGNGGTTPPATGKTCAEAGVDTSGVVTYPEFPKGDHAAGGDQLIHNGALWQANWWINTAPSASDSAWKMICKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYJ4</accession>
    <name>D0YYJ4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glutathione-dependent formaldehyde-activating enzyme</fullName>
            <ecNumber evidence="4">4.4.1.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">S-(hydroxymethyl)glutathione synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">gfa</name>
        <name evidence="6" type="ORF">VDA_002357</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>S-(hydroxymethyl)glutathione = formaldehyde + glutathione</text>
            <dbReference type="Rhea" id="RHEA:22488"/>
            <dbReference type="ChEBI" id="CHEBI:16842"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:58758"/>
            <dbReference type="EC" id="4.4.1.22"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="4">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">One-carbon metabolism; formaldehyde degradation; formate from formaldehyde (glutathione route): step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the Gfa family.</text>
    </comment>
    <dbReference type="EC" id="4.4.1.22" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002357"/>
    <dbReference type="EnsemblBacteria" id="EEZ41325">
        <property type="protein sequence ID" value="EEZ41325"/>
        <property type="gene ID" value="VDA_002357"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3791">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00562">
        <property type="reaction ID" value="UER00621"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051907">
        <property type="term" value="F:S-(hydroxymethyl)glutathione synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046294">
        <property type="term" value="P:formaldehyde catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00723">
        <property type="entry name" value="Formald_GSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006913">
        <property type="entry name" value="CENP-V/GFA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014185">
        <property type="entry name" value="Formald_GSH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04828">
        <property type="entry name" value="GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF033318">
        <property type="entry name" value="Formald_GSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="SSF51316"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02820">
        <property type="entry name" value="formald_GSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51891">
        <property type="entry name" value="CENP_V_GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CENP-V/GFA" evidence="5">
        <location>
            <begin position="39"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>structural</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>structural</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>structural</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>structural</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="206" mass="22357" checksum="8F6F8F16439C22D6" modified="2010-01-19" version="1">MKNFLSKLFSTSKAINMTTSKFNLHPALNQGFAATQANFTGGLLSCKCKTNQVTVKLTAQTAHNHACGCSKCWKPEGALFSQIAVVSSDKLTVIANANKLQVVDSAAVIKRHACKECGVHMFGRIEDSNHPFYGLDFVHTELSEQNGWTAPSFAAFVSSIIEAGTDPKDMDAIRSQFAEIGLPTYDCLSPALMDAIATHVYNQNHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYR2</accession>
    <name>D0YYR2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acetoacetyl-CoA reductase</fullName>
            <ecNumber evidence="3">1.1.1.36</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002425</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.36" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300068.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002425"/>
    <dbReference type="EnsemblBacteria" id="EEZ41393">
        <property type="protein sequence ID" value="EEZ41393"/>
        <property type="gene ID" value="VDA_002425"/>
    </dbReference>
    <dbReference type="GeneID" id="57341365"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1601931at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018454">
        <property type="term" value="F:acetoacetyl-CoA reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042619">
        <property type="term" value="P:poly-hydroxybutyrate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011283">
        <property type="entry name" value="Acetoacetyl-CoA_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01829">
        <property type="entry name" value="AcAcCoA_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="246" mass="26339" checksum="DBDA12746F3AF1EC" modified="2010-01-19" version="1">MSKLALITGAKGGIGSAISCQLVNDGYRVIATYFTGKHECALKWFKECGFTEQQVRLLELDVTNTQQCQERLTALLEEEGTIDVLVNNAGITRDSVFKKMSAEAWYDVINANLNSLFNVTHPLFAAMCEKGNGRVINISSVNALKGQFGQANYSAAKAGMIGFSKALAAEGARSGVTVNVVAPGYTATPMVQKIKPEILDAIKGEIPMKRLAEPEEIAKSVSFLASDAGAYITGETLSVNGGLYMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYU0</accession>
    <name>D0YYU0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glutathione synthase/Ribosomal protein S6 modification enzyme (Glutaminyl transferase)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002453</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300121.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002453"/>
    <dbReference type="EnsemblBacteria" id="EEZ41421">
        <property type="protein sequence ID" value="EEZ41421"/>
        <property type="gene ID" value="VDA_002453"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0189">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="937913at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011758">
        <property type="entry name" value="RimK-rel_E_lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039523">
        <property type="entry name" value="RimK-rel_E_lig_ATP-grasp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14397">
        <property type="entry name" value="ATPgrasp_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02291">
        <property type="entry name" value="rimK_rel_E_lig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ATP-grasp" evidence="2">
        <location>
            <begin position="48"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="324" mass="35652" checksum="332F45651930FF2E" modified="2010-01-19" version="1">MSFLSQFTSPSKLKKRGIMGMNQRNHSYIGRYNDRSRYPLVDNKLKTKIVAQEYGATVPELIGIIDSQATVKTIHNMVKDWPGFVIKPAQGSGGKGILVIVKHKDGVYVKPSGAEINKEDVERHITNTLAGLFSLGGKNDVAMVENLIEFDNVFDGFSYEGVPDVRVIVFKGYPVMAMMRCSTSASDGKANLHQGAVGVGIDIASGKAIRAVQFNKPIERHPDTDRLLSELEVPNWEKLLTLASSAWEMTGLGYMGTDMVLDKKLGPMVLELNARPGLAIQIANGCGLLPRLRHIEMMGTSFRMPTPEERVAYSAHQFGAKPQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ00</accession>
    <name>D0YZ00_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Beta-N-acetylhexosaminidase</fullName>
            <ecNumber evidence="3">3.2.1.52</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Beta-N-acetylhexosaminidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">N-acetyl-beta-glucosaminidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_002513</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides.</text>
            <dbReference type="EC" id="3.2.1.52"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 20 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.52" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300229.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002513"/>
    <dbReference type="EnsemblBacteria" id="EEZ41481">
        <property type="protein sequence ID" value="EEZ41481"/>
        <property type="gene ID" value="VDA_002513"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3525">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="727559at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004563">
        <property type="term" value="F:beta-N-acetylhexosaminidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102148">
        <property type="term" value="F:N-acetyl-beta-D-galactosaminidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030247">
        <property type="term" value="F:polysaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02847">
        <property type="entry name" value="E_set_Chitobiase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.379.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025705">
        <property type="entry name" value="Beta_hexosaminidase_sua/sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008965">
        <property type="entry name" value="CBM2/CBM3_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012291">
        <property type="entry name" value="CBM2_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004866">
        <property type="entry name" value="CHB/HEX_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004867">
        <property type="entry name" value="CHB_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015883">
        <property type="entry name" value="Glyco_hydro_20_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029018">
        <property type="entry name" value="Hex-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015882">
        <property type="entry name" value="HEX_bac_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22600">
        <property type="entry name" value="PTHR22600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03173">
        <property type="entry name" value="CHB_HEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03174">
        <property type="entry name" value="CHB_HEX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00728">
        <property type="entry name" value="Glyco_hydro_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02838">
        <property type="entry name" value="Glyco_hydro_20b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00738">
        <property type="entry name" value="GLHYDRLASE20"/>
    </dbReference>
    <dbReference type="SMART" id="SM01081">
        <property type="entry name" value="CHB_HEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49384">
        <property type="entry name" value="SSF49384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55545">
        <property type="entry name" value="SSF55545"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018744" description="Beta-N-acetylhexosaminidase" evidence="7">
        <location>
            <begin position="21"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="domain" description="CHB_HEX" evidence="8">
        <location>
            <begin position="35"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00030512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00033000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="887" mass="97986" checksum="B8F60E45DB90A824" modified="2010-01-19" version="1">MTLKLSALASVIALAVTGCASQGTNDQAVVNNLANNLEVNYKVVTNHGADNGLQCQNLGAEWASCDLINLTLVNNGPEVTSKDWKIYFHSIRQILDVQNDQFKITHVTGDLHTLEPTEKFDGFAEGETVVIPYVGEYWTLFENDYMPRAYVAAGKAEPKTIKSTDTENPADYLSPIDGDNWKRVPADNNTLATAQSRFDKNNDVQLLAKEEIAGTIVPTPLSTKLTGKTVSLTNGIAIDNSALSGDMLNAVKARLTMLGVNSNGSYPVKVELAPKHFAKANQVSGAYQLDVTPKGATILGFDKEGAFYGMQSLMSLMSTGTQNEIPTLKVVDAPRFDYRGIMVDVGRNFHSKEAILRTLDQMAAYKMNKLHMHLSDDEGWRLEIPGLPELTDIGAKRCHDLSETSCLLPQLGSGPEANNFGSGFYSKQDYLDILKYAKARGIEVIPEIDMPAHARAAVVAMEARYNRLAADGDMEAANEYRLMDPQDTSNVTTVQFYDKRSFINPCMDSSMNFVNKVISEVAAMHQEAGMPLTTWHFGGDEAKNIKQGAGFQDLNAGNKVAWKGNIDMSAENKPFEKSPMCKKLVDSGEVADYAHLPSHFAEKVSEVVNNKGIPNFQAWQDGLKYSKDSSAFATDKVRVNFWDVLYWGGTASAYDWADKGYDVIVSNPDYVYMDMPYEVDPQEKGYYWATRATDTRKMFGFAPENLPQNAETSLDRDGNGFSGKGTTESKGFYGLSAQLWSETVRTDDQYEYMVFPRVLAAAERAWHEASWENEYKTGVEYSQKSNLVNKKALNNDWARFANVLGQRELAKLDAAGIQYRVPVPGAKVIDGKLNMNVSMPGLKLQYSTDAGKTWVTYYNEVKPTVTGKVEVRAVSADGKRTSRVVSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ41</accession>
    <name>D0YZ41_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002554</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300312.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41522">
        <property type="protein sequence ID" value="EEZ41522"/>
        <property type="gene ID" value="VDA_002554"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502ZJ32">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1353890at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="149"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="191"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="219"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="245" mass="26063" checksum="8B13C479889A4D06" modified="2010-01-19" version="1">MLYAALLMIASVALTIVGVTALGHGQGEIPALALAIPALWILPQGKTAAWLLLSGLALFGYALPDQPLALSISLFMILPILAVSFSSKSPWQLGAMLIAVVIAMLFGLMALQTESKLSGSMGATCMQLMGVLMIWYAARSWRPVTGNTWWALVLVVPLLMGGMAPAALVALCVTGLIAAMQEMEKHKVGEWIPKMAWVLPAIGFATLVLAPQFEVPSPILVSWLLILGGGLLGEFLLEENEEEEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ55</accession>
    <name>D0YZ55_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Long-chain fatty acid transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_002568</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell outer membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the OmpP1/FadL family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300351.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002568"/>
    <dbReference type="EnsemblBacteria" id="EEZ41536">
        <property type="protein sequence ID" value="EEZ41536"/>
        <property type="gene ID" value="VDA_002568"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2067">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="620166at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005017">
        <property type="entry name" value="OMPP1/FadL/TodX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35093">
        <property type="entry name" value="PTHR35093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03349">
        <property type="entry name" value="Toluene_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018750" evidence="8">
        <location>
            <begin position="26"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="413" mass="45028" checksum="ECF900FEFA15EF77" modified="2010-01-19" version="1">MNKKRLFTKTLVAAAVTIASQQAMAAGFQLNAQSATGLGRAFAGDGVIADNASTMAKNPASMALFDAPALSLGVIAIDTDVKVKNATYTSPFGTNALPDEQIGGTSFAPNIYYIHPLNEKWTVGAGLYSNFGTKTEFSDKYAANAFGGLTDVKSVNLALSAAFRVNEHWSLGGGLDVIYGSGKLERYLPETKVPVVDITIPRKDLLNIDADGVALGFNLGTVYELNEDNRFGLSYRYSPTLDAKGDMSYIGADITNHKLKMPLPDMAEFSGFNKLNDKFAVHYSIQWIRWSEFDVLETSGGVNLNNYEWQDGWHYSIGGTYYLNDTWTLRAGYMHDTSAQDKRTSISVPDSARNWFSGGFSYHLDPKSSIDVGVTYLVGEDVKATESNPLGLGVDATTRANAWLYGIQYNRSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ61</accession>
    <name>D0YZ61_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cytochrome c heme lyase subunit CcmF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_002574</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002574"/>
    <dbReference type="EnsemblBacteria" id="EEZ41542">
        <property type="protein sequence ID" value="EEZ41542"/>
        <property type="gene ID" value="VDA_002574"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1138">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015232">
        <property type="term" value="F:heme transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032523">
        <property type="entry name" value="CcmF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002541">
        <property type="entry name" value="Cyt_c_assembly"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003567">
        <property type="entry name" value="Cyt_c_biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003568">
        <property type="entry name" value="Cyt_c_biogenesis_CcmF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43653">
        <property type="entry name" value="PTHR43653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16327">
        <property type="entry name" value="CcmF_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01578">
        <property type="entry name" value="Cytochrom_C_asm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01410">
        <property type="entry name" value="CCBIOGENESIS"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01411">
        <property type="entry name" value="CCMFBIOGNSIS"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00353">
        <property type="entry name" value="nrfE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0201">Cytochrome c-type biogenesis</keyword>
    <keyword evidence="10" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="9"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="134"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="158"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="198"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="237"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="278"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="310"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="335"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="376"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="500"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrom_C_asm" evidence="8">
        <location>
            <begin position="5"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="CcmF_C" evidence="9">
        <location>
            <begin position="200"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ41542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="537" mass="59680" checksum="B74AE206E5E3ACA0" modified="2010-01-19" version="1">MPLESVSRVLAVMGMISVGFLLFIILTSNPFLRTLPFFPVQGRDLNPLLQDPGLIIHPPMLYMGYVGFSVAFAFAIASLMTGRLDTAWARWSRPWTIAAWSFLTLGIALGSWWAYYELGWGGWWFWDPVENASFMPWLAGTALMHSLSVTEKRGTFKAWTVLLAIAAFSLSLLGTFLVRSGVLVSVHAFASDPSRGMFILGFLVVVIGGSLLLYALRGAQIRSRGNYSLFSRENMLFANNILLVTGLLVVLIGTLLPLVHKQLGLGSVSIGEPFFNTLFTWLMVPFAFVLGIGPLVRWKRDNISKIKKPLIISAIASVIFAFGSIYLFASTVEPLAVLGMWMAAWIVILHGFELYERATHRHSLIEGLGKLGRSHWAMVFGHIGLAISIIGITLVSNYDLERDVRLAPGQSVNVKGYDFYFAGLRDADGPNYDGYVADFKISKNNIMVTTLHAEKRIYTVAGSMMTEAAIDSGITRDLYVAMGEKLGDGAWAVRIYYKPFVNWMWFGALLMAIGGVFAISDKRYRFRKKAQITESKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZK6</accession>
    <name>D0YZK6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Sec translocon accessory complex subunit YajC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">yajC</name>
        <name evidence="11" type="ORF">VDA_002719</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the YajC family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300808.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002719"/>
    <dbReference type="EnsemblBacteria" id="EEZ41687">
        <property type="protein sequence ID" value="EEZ41687"/>
        <property type="gene ID" value="VDA_002719"/>
    </dbReference>
    <dbReference type="GeneID" id="57341009"/>
    <dbReference type="eggNOG" id="COG1862">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2082059at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003849">
        <property type="entry name" value="Preprotein_translocase_YajC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33909">
        <property type="entry name" value="PTHR33909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02699">
        <property type="entry name" value="YajC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01853">
        <property type="entry name" value="YAJCTRNLCASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01323">
        <property type="entry name" value="YajC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00739">
        <property type="entry name" value="yajC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0811">Translocation</keyword>
    <keyword evidence="7 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU366028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ41687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="112" mass="12169" checksum="A05C1D1EE0B8B30C" modified="2010-01-19" version="1">MSLFISNAYAAAEGAAPQGSSMQLFIMLGLFAVIFYFMIYRPQAKRVKEHKNLMASMGKGDEVLTNGGLLGRITKVSAESDYIVIALNDSTEVTIKKDFVTAVLPKGTMKSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZN7</accession>
    <name>D0YZN7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Formate dehydrogenase iron-sulfur subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">VDA_002750</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11 12">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="11 12">Binds 4 [4Fe-4S] clusters per subunit.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300903.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002750"/>
    <dbReference type="EnsemblBacteria" id="EEZ41718">
        <property type="protein sequence ID" value="EEZ41718"/>
        <property type="gene ID" value="VDA_002750"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0437">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1762646at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045333">
        <property type="term" value="P:cellular respiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015944">
        <property type="term" value="P:formate oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd10558">
        <property type="entry name" value="FDH-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006470">
        <property type="entry name" value="Formate_DH_bsu_Proteobacteria"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038384">
        <property type="entry name" value="Formate_DH_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014603">
        <property type="entry name" value="Formate_DH_Fe-S_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015246">
        <property type="entry name" value="Formate_DH_TM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13247">
        <property type="entry name" value="Fer4_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09163">
        <property type="entry name" value="Form-deh_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036298">
        <property type="entry name" value="FDH_4Fe4S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01582">
        <property type="entry name" value="FDH-beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 11 12" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="2 11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 11" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8 11 12" id="KW-0408">Iron</keyword>
    <keyword evidence="9 11 12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 11 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1 11" id="KW-0813">Transport</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="14">
        <location>
            <begin position="91"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="14">
        <location>
            <begin position="124"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>4</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>4</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>4</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>4</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR036298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR036298-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEZ41718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="296" mass="32676" checksum="9D52152027291ECB" modified="2010-01-19" version="1">MGMESQNIIRSSATSSITPAPHGRERQIEITKLIDVTCCTGCKGCMDACGEWNNLRGKVGTFEGSYQNPPNTTAEVWTTIHFKEIEEDNKFKWLFSKHSCMHCSDPGCLKACPEPGAIVQYENGVVDFDSEKCVGCGYCIAGCPFDIPRMNPVDNRVYKCTLCLDRLQAGQVPSCVKTCPTGALRFGSREEILEYANERVAALKAKGHSKAGIYNPEGVNGTHVIYILHDVTDPERYDLPKDPKISETVKLWKDDFKPLAAAGIVGTLALAAIHRVTVGRSRVKEEEDRNQKGDEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZP6</accession>
    <name>D0YZP6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Type II secretion system protein H</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">General secretion pathway protein H</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">VDA_002759</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300926.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002759"/>
    <dbReference type="EnsemblBacteria" id="EEZ41727">
        <property type="protein sequence ID" value="EEZ41727"/>
        <property type="gene ID" value="VDA_002759"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4970">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1974884at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022346">
        <property type="entry name" value="T2SS_GspH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016824">
        <property type="entry name" value="Tfp-pilus_assembly_FimT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12019">
        <property type="entry name" value="GspH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF024622">
        <property type="entry name" value="Tfp_FimT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0488">Methylation</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="domain" description="GspH" evidence="12">
        <location>
            <begin position="59"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF12019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ41727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="192" mass="21610" checksum="F4725428C3F2AA1C" modified="2010-01-19" version="1">MARETLFQLHHLQQNSLKCRGFTLLELIIAMSVMVVLLGAAAPSFSDLIERNKIKRLATEIEWLLVHAKSEAVMRGVEVYVYAPLVPGMRENSDWCVFSSIDTKKNCDDIDTSSLSSIKSADFSGVTFKNSSTLKQFSFDPIYGKPKNVGFGGNFDYQFGDYHLKTVIFNKTGRIYTCFEADSEKLSGYEKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZT6</accession>
    <name>D0YZT6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Delta endotoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_002799</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the delta endotoxin family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301039.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41767">
        <property type="protein sequence ID" value="EEZ41767"/>
        <property type="gene ID" value="VDA_002799"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5032XGN">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1646617at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090729">
        <property type="term" value="F:toxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001897">
        <property type="term" value="P:cytolysis by symbiont of host cells"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030435">
        <property type="term" value="P:sporulation resulting in formation of a cellular spore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038979">
        <property type="entry name" value="Pest_crys"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005639">
        <property type="entry name" value="Pest_crys_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036716">
        <property type="entry name" value="Pest_crys_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37003">
        <property type="entry name" value="PTHR37003"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03945">
        <property type="entry name" value="Endotoxin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56849">
        <property type="entry name" value="SSF56849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0749">Sporulation</keyword>
    <keyword evidence="2" id="KW-0800">Toxin</keyword>
    <keyword evidence="4" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018765" evidence="5">
        <location>
            <begin position="31"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="domain" description="Endotoxin_N" evidence="6">
        <location>
            <begin position="68"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="553" mass="63587" checksum="5308DCEB24BD62A9" modified="2010-01-19" version="1">MDNFTNERRLALKKLSALIALALFSSNSRANVILHGDNFDSTGVSVKAAFPDFSTDDIIEDFKLSLAFALHYVPYIGDILSFLVHLLWPSSQKDIWEEIREKVEKLIDQKLSEDTYERLKQVLEGLEGVLKQYLKTIQAGASDDEIKIHFLAANLFFINQRPWFQQKNHEYVLYPLFSIFSSLHLTLLRDGLINGKHLFSNNEYELLKKDMKEYTKSYSDYLLKTVDAERYKLKEHSPPVGQHKTEYYNYFADFNAVTIKYCDDYIEMFRQMDVDLNPQAFEFDRTQFKDIFSKAYGTADDWDGTCRGFARGGMGVQSIYTQPAESFNSIFLDFFDGRPVNLNVAYPDGKGPYNLDKHRVNSTQVIADYHRGVETRTVAIEAIDGEIFPISSVILKSGSIPSYLTLLDTNGKSYNLWNSYEAFQQEEVKVSFAPRRLSTITAWSHSRYYHYALGCMILGFSWVPPKNKTPALLRQHYKSMLTEPDLDELSRIHHIDALDYIKPKDESQRDQYWSELNDIADKNQVEQERNGGAIGGAALTGLIGSVLLKRFIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZW0</accession>
    <name>D0YZW0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Glycerol dehydrogenase</fullName>
            <ecNumber evidence="8">1.1.1.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_002823</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="4">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the iron-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.6" evidence="8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301112.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002823"/>
    <dbReference type="EnsemblBacteria" id="EEZ41791">
        <property type="protein sequence ID" value="EEZ41791"/>
        <property type="gene ID" value="VDA_002823"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0371">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="717704at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008888">
        <property type="term" value="F:glycerol dehydrogenase [NAD+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001670">
        <property type="entry name" value="ADH_Fe/GldA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018211">
        <property type="entry name" value="ADH_Fe_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016205">
        <property type="entry name" value="Glycerol_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43616">
        <property type="entry name" value="PTHR43616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00465">
        <property type="entry name" value="Fe-ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000112">
        <property type="entry name" value="Glycerol_dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00913">
        <property type="entry name" value="ADH_IRON_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="3 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Fe-ADH" evidence="7">
        <location>
            <begin position="9"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="95"/>
            <end position="99"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="117"/>
            <end position="120"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="172"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="255"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000112-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000112-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000112-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ41791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="365" mass="39235" checksum="16DECEF9659113DB" modified="2010-01-19" version="1">MIPRSVTSPKKFIIGQNLLSQLPDYVKDFGDSAFLICDEFILDRVNQEAIPALQDAGLKGASEKFQYECTDEEIGRLDHMARELGANVIVGIGGGKTLDVAKAVAHFSHKPVIIFPTIASTDAPCTALSVVYNTDGSFNRYLFLPQNPDAVIADTAIISAAPARFFAAGIGDALATFFEARACCYADGLNLVQKKVSRTGLGLAMMCYDLILENVEMAMDAVRNHVVTPALEELIEATIYLSGVGAESGGLAAAHAISNGMSALPALHHIQHGEKVAFGLLVQLVLEKADTEEIENVIYVMKTAGLPLTLADFGVTEFVEADWRQVAEIACEPGDTMCNMPVKVNPQKVYQAIVAADALAQRYHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZX1</accession>
    <name>D0YZX1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transcription termination/antitermination protein NusA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">nusA</name>
        <name evidence="9" type="ORF">VDA_002834</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Participates in both transcription termination and antitermination.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the NusA family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301147.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002834"/>
    <dbReference type="EnsemblBacteria" id="EEZ41802">
        <property type="protein sequence ID" value="EEZ41802"/>
        <property type="gene ID" value="VDA_002834"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0195">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="384865at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription, termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031564">
        <property type="term" value="P:transcription antitermination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1480.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00945_B">
        <property type="entry name" value="NusA_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010995">
        <property type="entry name" value="DNA_repair_Rad51/TF_NusA_a-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025249">
        <property type="entry name" value="KH_dom_NusA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030842">
        <property type="entry name" value="NusA_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036555">
        <property type="entry name" value="NusA_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013735">
        <property type="entry name" value="TF_NusA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010214">
        <property type="entry name" value="Tscrpt_termin_fac_NusA_C_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010213">
        <property type="entry name" value="Tscrpt_termination_fac_NusA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22648">
        <property type="entry name" value="PTHR22648"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13184">
        <property type="entry name" value="KH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08529">
        <property type="entry name" value="NusA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47794">
        <property type="entry name" value="SSF47794"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="SSF54814"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69705">
        <property type="entry name" value="SSF69705"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01953">
        <property type="entry name" value="NusA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01954">
        <property type="entry name" value="nusA_Cterm_rpt"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 7" id="KW-0889">Transcription antitermination</keyword>
    <keyword evidence="5 7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="1 7" id="KW-0806">Transcription termination</keyword>
    <feature type="domain" description="S1 motif" evidence="8">
        <location>
            <begin position="135"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="494" mass="54758" checksum="305E05878FF5BFD6" modified="2010-01-19" version="1">MNKEILAVVEAVSNEKAVPRERIFEALEIALATATKKKYEAEIDVRVTIDRKTGEFETFRRWKAVDEVTQPTLEITLEAAQFEDETVELGDFVEDEIQSVTFDRITTQTAKQVIVQKVREAERAQIVAQFVDNEGDLITGVVKKVNRDAVIVDLGNNAEAVIGRDDQLPRENFRPGDRVRGLLYKVAPEARGFQLFMTRSKPAMLSELFRIEVPEIGEELIELMGAARDPGSRAKIAVKTNDKRIDPVGACVGMRGARVQAVSGELGGERIDIVLWDENPAQYVINAMAPAEVSSIIVDEDSHTMDIAVEKANLAQAIGRNGQNVRLASQLTGWELNVMTVEDLQKKHQEEAQESIDTFTKYLDIDEDFASVLVTEGFTTLEEIAYVPVNELLEVEGLNEETIDELRNRAKEALTTIALAKEESLDAEPAEDLLALEGLERELAFKLAAKGILTLEDLADQGTDDLIDIEGVDEAKAGELIMAARNICWFGDEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZX2</accession>
    <name>D0YZX2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ribosome maturation factor RimP</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rimP</name>
        <name evidence="6" type="ORF">VDA_002835</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Required for maturation of 30S ribosomal subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RimP family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301149.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002835"/>
    <dbReference type="EnsemblBacteria" id="EEZ41803">
        <property type="protein sequence ID" value="EEZ41803"/>
        <property type="gene ID" value="VDA_002835"/>
    </dbReference>
    <dbReference type="GeneID" id="57340883"/>
    <dbReference type="eggNOG" id="COG0779">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1595498at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01734">
        <property type="entry name" value="YlxS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01077">
        <property type="entry name" value="RimP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003728">
        <property type="entry name" value="Ribosome_maturation_RimP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028998">
        <property type="entry name" value="RimP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036847">
        <property type="entry name" value="RimP_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028989">
        <property type="entry name" value="RimP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035956">
        <property type="entry name" value="RimP_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33867">
        <property type="entry name" value="PTHR33867"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02576">
        <property type="entry name" value="DUF150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17384">
        <property type="entry name" value="DUF150_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74942">
        <property type="entry name" value="SSF74942"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75420">
        <property type="entry name" value="SSF75420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="DUF150" evidence="4">
        <location>
            <begin position="11"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="DUF150_C" evidence="5">
        <location>
            <begin position="86"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="151" mass="16655" checksum="E6E559802B985196" modified="2010-01-19" version="1">MTALETQLTEMLEPSVAALGYELVGLEFIRAGEHSTLRIFIDKENGINVEDCAEVSRQVSAVMDVEDPITVAYNLEVSSPGLERPLFKAAHYEQFIGHEVSLVLKMAMGNRRKWKGDIVAVDGELVTLNVDGNEECFALSNISKANLVPKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZY4</accession>
    <name>D0YZY4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">4-hydroxy-tetrahydrodipicolinate reductase</fullName>
            <shortName evidence="9">HTPA reductase</shortName>
            <ecNumber evidence="9">1.17.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">dapB</name>
        <name evidence="12" type="ORF">VDA_002847</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>(S)-2,3,4,5-tetrahydrodipicolinate + H2O + NAD(+) = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:35323"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16845"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:67139"/>
            <dbReference type="EC" id="1.17.1.8"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>(S)-2,3,4,5-tetrahydrodipicolinate + H2O + NADP(+) = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:35331"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16845"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:67139"/>
            <dbReference type="EC" id="1.17.1.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="9">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 4/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the DapB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.</text>
    </comment>
    <dbReference type="EC" id="1.17.1.8" evidence="9"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301183.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002847"/>
    <dbReference type="EnsemblBacteria" id="EEZ41815">
        <property type="protein sequence ID" value="EEZ41815"/>
        <property type="gene ID" value="VDA_002847"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0289">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="803114at2"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00018"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008839">
        <property type="term" value="F:4-hydroxy-tetrahydrodipicolinate reductase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016726">
        <property type="term" value="F:oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019877">
        <property type="term" value="P:diaminopimelate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00102">
        <property type="entry name" value="DapB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022663">
        <property type="entry name" value="DapB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000846">
        <property type="entry name" value="DapB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022664">
        <property type="entry name" value="DapB_N_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023940">
        <property type="entry name" value="DHDPR_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20836">
        <property type="entry name" value="PTHR20836"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05173">
        <property type="entry name" value="DapB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01113">
        <property type="entry name" value="DapB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000161">
        <property type="entry name" value="DHPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00036">
        <property type="entry name" value="dapB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01298">
        <property type="entry name" value="DAPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9" id="KW-0220">Diaminopimelate biosynthesis</keyword>
    <keyword evidence="8 9" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="7 9" id="KW-0520">NAD</keyword>
    <keyword evidence="4 9" id="KW-0521">NADP</keyword>
    <keyword evidence="6 9 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DapB_N" evidence="10">
        <location>
            <begin position="2"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="DapB_C" evidence="11">
        <location>
            <begin position="128"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="(S)-2,3,4,5-tetrahydrodipicolinate binding" evidence="9">
        <location>
            <begin position="165"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="9">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="9">
        <location>
            <position position="159"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="8"/>
            <end position="13"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="98"/>
            <end position="100"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="122"/>
            <end position="125"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>(S)-2,3,4,5-tetrahydrodipicolinate</name>
            <dbReference type="ChEBI" id="CHEBI:16845"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF05173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ41815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="268" mass="28400" checksum="1E1C4DEDF461E679" modified="2010-01-19" version="1">MVRIAIAGAGGRMGRQLIKATTLVDSATLGVAVERTGSTLVGVDAGELAGVGLLNIQVIDDLAAQMDQFDVLIDFTAPSATLANLELCKAHQKAIVIGTTGFTEQERASIDQAAQSIPVVMAPNYSVGVNLMFKLLEQAAKVMGDYCDIEIIEAHHRHKVDAPSGTAIGMGEAIAGAMDKKLSDVAVYAREGITGERKQSEIGFATIRAGDIVGEHTALFADIGERIEITHKASDRMTFANGAVRAAIWLVEQKTGFYTMQDVLGLNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z067</accession>
    <name>D0Z067_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Aspartate carbamoyltransferase regulatory chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pyrI</name>
        <name evidence="10" type="ORF">VDA_002930</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 7">Involved in allosteric regulation of aspartate carbamoyltransferase.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Contains catalytic and regulatory chains.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the PyrI family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301380.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002930"/>
    <dbReference type="EnsemblBacteria" id="EEZ41898">
        <property type="protein sequence ID" value="EEZ41898"/>
        <property type="gene ID" value="VDA_002930"/>
    </dbReference>
    <dbReference type="GeneID" id="57340766"/>
    <dbReference type="eggNOG" id="COG1781">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1657328at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009347">
        <property type="term" value="C:aspartate carbamoyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006221">
        <property type="term" value="P:pyrimidine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00002">
        <property type="entry name" value="Asp_carb_tr_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020545">
        <property type="entry name" value="Asp_carbamoyltransf_reg_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002801">
        <property type="entry name" value="Asp_carbamoylTrfase_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020542">
        <property type="entry name" value="Asp_carbamoyltrfase_reg_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036792">
        <property type="entry name" value="Asp_carbatrfase_reg_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036793">
        <property type="entry name" value="Asp_carbatrfase_reg_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35805">
        <property type="entry name" value="PTHR35805"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01948">
        <property type="entry name" value="PyrI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02748">
        <property type="entry name" value="PyrI_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54893">
        <property type="entry name" value="SSF54893"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57825">
        <property type="entry name" value="SSF57825"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00240">
        <property type="entry name" value="ATCase_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 7" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="PyrI" evidence="8">
        <location>
            <begin position="7"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="PyrI_C" evidence="9">
        <location>
            <begin position="102"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ41898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="154" mass="17204" checksum="601054EDADECCC13" modified="2010-01-19" version="1">MVKENKLQVEAIKNGSVIDHIPANIGIKVLKLFGMHKANQRITVGLNLPSSALGAKDLIKIENIYITEEQANQLALYAPKATVNQIENYEVVKKLALSLPEQIHAIFKCPNSNCISHGEPVDSSFKVLKKNDDVQLKCRYCEKVFSREIVTECN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0A3</accession>
    <name>D0Z0A3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF547 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002966</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301434.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002966"/>
    <dbReference type="EnsemblBacteria" id="EEZ41934">
        <property type="protein sequence ID" value="EEZ41934"/>
        <property type="gene ID" value="VDA_002966"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0398">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="856351at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006869">
        <property type="entry name" value="DUF547"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04784">
        <property type="entry name" value="DUF547"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019927" description="DUF547 domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="DUF547" evidence="2">
        <location>
            <begin position="89"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="266" mass="30908" checksum="1094B46F62450761" modified="2010-01-19" version="1">MRSWLIIFTLISACFSSGIWAAPKAQLWPYWQTNNATSQQTIDHQVWQQLLTRYVTVTPHQTYFNYRLVTQQSRQQLQQYIQGLTAIDPRKLNRNEQFAYWVNLYNAATVDLILQNYPIASITKLGGLFSFGLWDEKLLTINGRSLTLNDIEHRILRPIWQDKRIHYVVNCASLGCPDLMPTALTASNSQTLLDQAATRFINSTKGVDVINANNNQIQLSSIYDWYSSDFGSQSELNAHINHYRKQPVSLDKVRFDYNWQLNELKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0B3</accession>
    <name>D0Z0B3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">4-hydroxythreonine-4-phosphate dehydrogenase</fullName>
            <ecNumber evidence="4">1.1.1.262</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">4-(phosphohydroxy)-L-threonine dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">pdxA</name>
        <name evidence="5" type="ORF">VDA_002976</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>4-(phosphooxy)-L-threonine + NAD(+) = 3-amino-2-oxopropyl phosphate + CO2 + NADH</text>
            <dbReference type="Rhea" id="RHEA:32275"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57279"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58452"/>
            <dbReference type="EC" id="1.1.1.262"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="4">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <text evidence="4">Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; pyridoxine 5'-phosphate biosynthesis; pyridoxine 5'-phosphate from D-erythrose 4-phosphate: step 4/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="4">The active site is located at the dimer interface.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PdxA family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.262" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301445.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002976"/>
    <dbReference type="EnsemblBacteria" id="EEZ41944">
        <property type="protein sequence ID" value="EEZ41944"/>
        <property type="gene ID" value="VDA_002976"/>
    </dbReference>
    <dbReference type="GeneID" id="57340713"/>
    <dbReference type="eggNOG" id="COG1995">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1414545at2"/>
    <dbReference type="UniPathway" id="UPA00244">
        <property type="reaction ID" value="UER00312"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050570">
        <property type="term" value="F:4-hydroxythreonine-4-phosphate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050897">
        <property type="term" value="F:cobalt ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042823">
        <property type="term" value="P:pyridoxal phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008615">
        <property type="term" value="P:pyridoxine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00536">
        <property type="entry name" value="PdxA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037510">
        <property type="entry name" value="PdxA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005255">
        <property type="entry name" value="PdxA_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30004">
        <property type="entry name" value="PTHR30004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04166">
        <property type="entry name" value="PdxA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00557">
        <property type="entry name" value="pdxA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0170">Cobalt</keyword>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="3 4 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0664">Pyridoxine biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="4">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="266"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="274"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="283"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="292"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="329" mass="35317" checksum="5496A6C3A6A347B1" modified="2010-01-19" version="1">MDKVKRIAITPGEPAGIGPDLVLALSQHNWPHQLVICADAQVMVERAVQLGIQVEIIRYDQTQPAEPHRAGTLVVAQIDTQEAVCAGQLNEANGHYVLNTLARAAQGCLSGEFSAIVTGPVHKGVINRAGVAFSGHTEFFAEQSNTAQVVMMLATEGLRVALVTTHIPLSCVAKAITPQRLEQVIRILHQDLVTKFGLAAPKIYVCGLNPHAGEDGCLGHEEIDVITPTLNRLREENIHLVGPLPADTIFQPKYLAEADTVLAMYHDQGLPVLKFKGFGKSVNITLGLPFIRTSVDHGTALELAGTGQAEIGSLWTALTHAVELVEKQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0B5</accession>
    <name>D0Z0B5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Bis(5'-nucleosyl)-tetraphosphatase, symmetrical</fullName>
            <ecNumber evidence="5">3.6.1.41</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Ap4A hydrolase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Diadenosine tetraphosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">apaH</name>
        <name evidence="7" type="ORF">VDA_002978</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 5">Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>H2O + P(1),P(4)-bis(5'-adenosyl) tetraphosphate = 2 ADP + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:24252"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58141"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.1.41"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the Ap4A hydrolase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.41" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301447.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002978"/>
    <dbReference type="EnsemblBacteria" id="EEZ41946">
        <property type="protein sequence ID" value="EEZ41946"/>
        <property type="gene ID" value="VDA_002978"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0639">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="900869at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008803">
        <property type="term" value="F:bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07422">
        <property type="entry name" value="MPP_ApaH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00199">
        <property type="entry name" value="ApaH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004617">
        <property type="entry name" value="ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000903">
        <property type="entry name" value="B5n-ttraPtase_sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00668">
        <property type="entry name" value="apaH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="6">
        <location>
            <begin position="3"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="273" mass="31136" checksum="4804CA56D32BF7C9" modified="2010-01-19" version="1">MATYIVGDIQGCFDDLEKLLQQVQFDANTDELWLAGDLVARGPKSLQTLRFIKALGNAATIVLGNHDLHLLAVANGIAKAKSKDKIHDIFTAPDGEELLNWLRMQPILAEHPQHNFVMVHAGITPQWSLEQARTQARHVESVLQSDRYLWLLTNMYGDGPNLWQDNLTELEQLRFTINNFTRMRFCYPDGRLDMACKEGPDSQSVTELKPWFDIPRLTPMEKTILFGHWAALMGHQDEYCIGLDTGCVWGNSLTMMRWEDKAFFSTPCPIYSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0C2</accession>
    <name>D0Z0C2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative octaprenyl-diphosphate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002985</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002985"/>
    <dbReference type="EnsemblBacteria" id="EEZ41953">
        <property type="protein sequence ID" value="EEZ41953"/>
        <property type="gene ID" value="VDA_002985"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0142">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033749">
        <property type="entry name" value="Polyprenyl_synt_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00444">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="189" mass="20710" checksum="10930B012B8E2E22" modified="2010-01-19" version="1">MSAATNVIAEGEVQQLMNCNDPDTTEESYMEVIYSKTARLFEAATQVAAIIAKASPEVETAFQDYGRYLGTAFQLIDDVLDYVADGKEMGKNVGDDLAEGKPTLPLLYAMRHGNPQQAAMIREAIEQANGMDKLDEILTCMRETGALEYTQQRAEQEADKAIAALDILPESAHKQALIALAHLSVQRNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0F2</accession>
    <name>D0Z0F2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chemotaxis protein CheX</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_003016</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003016"/>
    <dbReference type="EnsemblBacteria" id="EEZ41983">
        <property type="protein sequence ID" value="EEZ41983"/>
        <property type="gene ID" value="VDA_003016"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1406">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028976">
        <property type="entry name" value="CheC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038756">
        <property type="entry name" value="CheX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028051">
        <property type="entry name" value="CheX-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39452">
        <property type="entry name" value="PTHR39452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13690">
        <property type="entry name" value="CheX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103039">
        <property type="entry name" value="SSF103039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CheX" evidence="2">
        <location>
            <begin position="2"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="66" mass="7155" checksum="4444CEAAA25BB41F" modified="2010-01-19" version="1">MVGEITNMVTGGAKRILADKGYDFDMATPAVVSGRGHTITHKCEGAVIIMPFESDYGRAFIEICFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0H4</accession>
    <name>D0Z0H4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA threonylcarbamoyladenosine biosynthesis protein TsaE</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaE</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_003038</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TsaE family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003038"/>
    <dbReference type="EnsemblBacteria" id="EEZ42005">
        <property type="protein sequence ID" value="EEZ42005"/>
        <property type="gene ID" value="VDA_003038"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0802">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002949">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003442">
        <property type="entry name" value="T6A_TsaE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02367">
        <property type="entry name" value="TsaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00032441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ42005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="62" mass="7156" checksum="436A00DCA2FA41EC" modified="2010-01-19" version="1">MGIRDYFSNDAICLVEWPEKGTGLLPQPDLELEMLYHGEQRKVIITAQSEYGEQLLSRLEKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0J1</accession>
    <name>D0Z0J1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Site-specific recombinase XerD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_003055</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ42022">
        <property type="protein sequence ID" value="EEZ42022"/>
        <property type="gene ID" value="VDA_003055"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0582">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="785253at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0229">DNA integration</keyword>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ42022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="161" mass="18010" checksum="BF2BEFA027C07CBB" modified="2010-01-19" version="1">MRSIWTHAYKLGEIDSKTSPFFDHDLSAYRGEGSKQKQLFSHDQLSKVLKEASESIRDLVRLGLFPKARLSERCNAHEEIIEDVRCMVIKKGKTAAAARTIPIAKQIQDIQLPLGLDHKSAGRVFSRFKTSKVTTDSSPPSIPCACISLPQRNVQELMSSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0K8</accession>
    <name>D0Z0K8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 13">Biotin carboxylase</fullName>
            <ecNumber evidence="5 13">6.3.4.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11 13">Acetyl-coenzyme A carboxylase biotin carboxylase subunit A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">VDA_003072</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 13">This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>ATP + hydrogencarbonate + N(6)-biotinyl-L-lysyl-[protein] = ADP + H(+) + N(6)-carboxybiotinyl-L-lysyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13501"/>
            <dbReference type="Rhea" id="RHEA-COMP:10505"/>
            <dbReference type="Rhea" id="RHEA-COMP:10506"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83144"/>
            <dbReference type="ChEBI" id="CHEBI:83145"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.14"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 13">Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 13">Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.14" evidence="5 13"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301757.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003072"/>
    <dbReference type="EnsemblBacteria" id="EEZ42039">
        <property type="protein sequence ID" value="EEZ42039"/>
        <property type="gene ID" value="VDA_003072"/>
    </dbReference>
    <dbReference type="GeneID" id="57340455"/>
    <dbReference type="eggNOG" id="COG0439">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="361205at2"/>
    <dbReference type="UniPathway" id="UPA00655">
        <property type="reaction ID" value="UER00711"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003989">
        <property type="term" value="F:acetyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004075">
        <property type="term" value="F:biotin carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001295">
        <property type="term" value="P:malonyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004549">
        <property type="entry name" value="Acetyl_CoA_COase_biotin_COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005481">
        <property type="entry name" value="BC-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011764">
        <property type="entry name" value="Biotin_carboxylation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005482">
        <property type="entry name" value="Biotin_COase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CbamoylP_synth_lsu-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02785">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00289">
        <property type="entry name" value="Biotin_carb_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00878">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="SSF51246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00514">
        <property type="entry name" value="accC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50979">
        <property type="entry name" value="BC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00866">
        <property type="entry name" value="CPSASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9 12 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 13" id="KW-0092">Biotin</keyword>
    <keyword evidence="13" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="13" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="7 13 16" id="KW-0436">Ligase</keyword>
    <keyword evidence="13" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="13" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 12 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin carboxylation" evidence="15">
        <location>
            <begin position="1"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="14">
        <location>
            <begin position="120"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00033786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU365063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EEZ42039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="447" mass="49421" checksum="44A2DDD4907851C0" modified="2010-01-19" version="1">MLDKVVIANRGEIALRILRACKELGIKTVAVHSTADRDLKHVLLADESVCIGPARGTESYLNIPRIISAAEITGAVAIHPGYGFLSENADFAEQVERSGFIFVGPKAETIRLMGDKVSAINAMKKAGVPCVPGSDGPLGNDEDKNKAIAKRIGYPVIIKASGGGGGRGMRVVRNEKEIVEAIAMTRAEAKACFNNDMVYMEKYLENPRHIEVQVLADGQGNAIHLGERDCSMQRRHQKVVEEAPAPGITEEMRKYIGERCTRACIEIGYRGAGTFEFLYENGEFYFIEMNTRIQVEHTITEMVTGIDLVKEQLRIAAGQPLSYTQDDIKLRGHSIECRINAEDPVRFLPSPGKIERFHSPGGMGVRWESHIYTGYTVPPHYDSMIGKLITYGENRDVAISRMKNALSEMIIEGIHVNVPLLLDIMNDENFQHGGANIHYLEKKLGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0V6</accession>
    <name>D0Z0V6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">NAD(FAD)-utilizing dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_003170</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ42137">
        <property type="protein sequence ID" value="EEZ42137"/>
        <property type="gene ID" value="VDA_003170"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2081">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004792">
        <property type="entry name" value="BaiN-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023166">
        <property type="entry name" value="HI0933-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42887">
        <property type="entry name" value="PTHR42887"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00275">
        <property type="entry name" value="TIGR00275"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ42137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="411" mass="45199" checksum="9656A5F3D2C8069F" modified="2010-01-19" version="1">MLASFFIVDSQLEQTTMAKKFDVVVIGAGAAGLMCAAEAGKRGRSVLVVDHGKKPGRKILISGGGRCNFTNYDVNANNYVCRNPHFVKSALSQYTNWDFIAMVAKYDIAYEERDHGQLFCLDSAKDIVNMLLAECDQPTVSQRYQVDVHNIEQTDSGFRLMLNTESVECESLVVATGGLSMPKLGATPFGYQIAEQFGLKMVPTTAGLVPFTLHVEDKDAFADLSGIAIPAVVETENGVSFKENLLFTHRGLSGPVILQASSYWLPGQAVTIDLLPDVSLDETFNAMREKHPNQSLKNSLARLLPKRLIEVLIERGDLVDKPLKQFNPKDISQMHQYFHHWTIAPNGTEGYRTAEVTLGGVDTDELSSKTLEAKKVKGLFFAGEVMDVSGWLGGYNFQWAWSSGFVVGQNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z127</accession>
    <name>D0Z127_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_003241</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ42208">
        <property type="protein sequence ID" value="EEZ42208"/>
        <property type="gene ID" value="VDA_003241"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ42208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="37" mass="4197" checksum="27BB6889B62C8A09" modified="2010-01-19" version="1">MDLGAKLIAPRLDIDVSAHPVPEEPAEIWLEQWKNTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1F1</accession>
    <name>D0Z1F1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">2,3-bisphosphoglycerate-independent phosphoglycerate mutase</fullName>
            <shortName evidence="8">BPG-independent PGAM</shortName>
            <shortName evidence="8">Phosphoglyceromutase</shortName>
            <shortName evidence="8">iPGM</shortName>
            <ecNumber evidence="8">5.4.2.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">gpmI</name>
        <name evidence="14" type="ORF">VDA_003365</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>(2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate</text>
            <dbReference type="Rhea" id="RHEA:15901"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="ChEBI" id="CHEBI:58289"/>
            <dbReference type="EC" id="5.4.2.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="8">Binds 2 manganese ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the BPG-independent phosphoglycerate mutase family.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.12" evidence="8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302577.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003365"/>
    <dbReference type="EnsemblBacteria" id="EEZ42332">
        <property type="protein sequence ID" value="EEZ42332"/>
        <property type="gene ID" value="VDA_003365"/>
    </dbReference>
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        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="7 8 14" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6 8 11" id="KW-0464">Manganese</keyword>
    <keyword evidence="4 8 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metalloenzyme" evidence="12">
        <location>
            <begin position="5"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="domain" description="iPGM_N" evidence="13">
        <location>
            <begin position="83"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8 10">
        <location>
            <begin position="154"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8 10">
        <location>
            <begin position="262"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphoserine intermediate" evidence="8 9">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8 11">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
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        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
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            <label>2</label>
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        <location>
            <position position="124"/>
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        <ligand>
            <name>substrate</name>
        </ligand>
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        <location>
            <position position="186"/>
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            <name>substrate</name>
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            <position position="402"/>
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            <label>1</label>
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        <location>
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            <dbReference type="ARBA" id="ARBA00000370"/>
        </source>
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        <source>
            <dbReference type="ARBA" id="ARBA00004798"/>
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        <source>
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        <source>
            <dbReference type="HAMAP-Rule" id="MF_01038"/>
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    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001492-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001492-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR001492-3"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF01676"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF06415"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EEZ42332.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="513" mass="55796" checksum="0E66AE31E1CDC2EF" modified="2010-01-19" version="1">MSAKKPLALVILDGWGYREDAANNAIANANTPVMDSLMANEAHTLISASGMDVGLPDGQMGNSEVGHTNIGAGRVVYQDLTRITKAISDGEFFENDVLVAAMDAAIKEGKAVHIMGLMSPGGVHSHEDHIKAAVEMAAKRGAEKIYLHCFLDGRDTPPRSAQHSLERFQELFAKLGKGRVASLVGRYYAMDRDNNWDRVEQAYDLLTAAQGEFTAESAVAGLEAAYARNENDEFVKATVIRAEGQEDAAMQDGDAVIFMNYRADRARQITRAFEAGFESFARKQFPQLADFVMLTQYAADIELSTAFPPASLENTLGEWLSKKGKKQLRISETEKYAHVTFFFNGGVENEFDGESRQLVASPKVATYDLQPEMSSPELTDKLVAAIKGGEFDVIICNYPNGDMVGHTGIYDAAVKACEALDGCIGRVVEAIREVNGQLLITADHGNAEMMINPETGEIHTAHTNLPVPLIYVGDKSLTLKDNGKLSDLAPTMLALSDMEIPSEMSGQVLFDLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1H5</accession>
    <name>D0Z1H5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Primosomal protein N'</fullName>
            <ecNumber evidence="9">3.6.4.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">ATP-dependent helicase PriA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">priA</name>
        <name evidence="12" type="ORF">VDA_003389</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the primosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the helicase family. PriA subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="9"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302625.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003389"/>
    <dbReference type="EnsemblBacteria" id="EEZ42356">
        <property type="protein sequence ID" value="EEZ42356"/>
        <property type="gene ID" value="VDA_003389"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1198">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1132322at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990077">
        <property type="term" value="C:primosome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006269">
        <property type="term" value="P:DNA replication, synthesis of RNA primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006268">
        <property type="term" value="P:DNA unwinding involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00983">
        <property type="entry name" value="PriA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005259">
        <property type="entry name" value="PriA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041222">
        <property type="entry name" value="PriA_3primeBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042115">
        <property type="entry name" value="PriA_3primeBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041236">
        <property type="entry name" value="PriA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040498">
        <property type="entry name" value="PriA_CRR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17764">
        <property type="entry name" value="PriA_3primeBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18074">
        <property type="entry name" value="PriA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18319">
        <property type="entry name" value="PriA_CRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00595">
        <property type="entry name" value="priA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 9" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 9 12" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1 9" id="KW-0639">Primosome</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="212"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="472"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="9">
        <location>
            <begin position="437"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="9">
        <location>
            <begin position="464"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ42356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="734" mass="82004" checksum="787A2F185369760A" modified="2010-01-19" version="1">MTGNIAQVALPVPLDKRFDYKIHPQQCPVVGGRVKVPFGRQQLVGIVTKISDRSDFPLEQLKAINEVIDSQPLWSDSLYQLLNWASGFYQYPLGDTLANAMPTLLRKGRVAELSSIKYWSITEEGKNQELTSVTKKAPKQAQILNLLHAGNMSHEQLLDAEVSPAALKTLNEKQWITTFEQKPKTQDWPQQFAITEQKPQLNTEQALAVATVNANPNFGCYLLEGITGSGKTEVYLNLLEPVLAAGKQALILVPEIGLMPQTINRFRRRFNVPLKTIHSGLNDTERLTAWLAGRDNQAGIIIGTRSALFTPFANLGIIIVDEEHDASYKQQDSLRYHARDLAVMRASQDNIPIVLGSATPALETINNAKSGKYHHLTLTKRAGNASKARQGVIDVKGLYLEAGLSAPLIAEMRKHLTAGNQVILFLNRRGFSPALMCHECGWLAECPRCDAYYTLHQQSGELRCHHCATQRPIMHQCQNCGSTQLHAVGVGTEQLEAQLAELFPEYKTVRIDRDSTRRKGSLENYLEAIRRNEYQILIGTQMLAKGHHFPNVTLVGLIDVDGALFSNDFRASERLAQLYVQVAGRAGRASKPGEVLLQTHHPEHALLQSLLRQGYGSFAEHALIERKQAMLPPYSYLVLFRAESNHSDQVQQFLQQVRSIFESSPLFDSDSFVMGPNPAPLARRAGRYRWQLIVQAPSRKVLQNMLNIAKPAINLLPLAKKVRWSIDVEPQDLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1H9</accession>
    <name>D0Z1H9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cystathionine gamma-synthase</fullName>
            <ecNumber evidence="4">2.5.1.48</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_003393</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.48" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003393"/>
    <dbReference type="EnsemblBacteria" id="EEZ42360">
        <property type="protein sequence ID" value="EEZ42360"/>
        <property type="gene ID" value="VDA_003393"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0626">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003962">
        <property type="term" value="F:cystathionine gamma-synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102028">
        <property type="term" value="F:cystathionine gamma-synthase activity (acts on O-phosphohomoserine)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00614">
        <property type="entry name" value="CGS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011821">
        <property type="entry name" value="O_succ_thio_ly"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808">
        <property type="entry name" value="PTHR11808"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001434">
        <property type="entry name" value="CGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02080">
        <property type="entry name" value="O_succ_thio_ly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00868">
        <property type="entry name" value="CYS_MET_METAB_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR001434-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ42360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="401" mass="43078" checksum="D521662AE38A6B86" modified="2010-01-19" version="1">MNKNSTTKSLGMASMSNKQSATIAVRSGIDCDSQYNAVVPPIYLTSTYSFNALGEVPQYDYSRSGNPTRNTLAEALAQLEQGAGAIVTNCGTAAINLLVSALLGPNDLVVAPHDCYGGTYRLLNTRAQKGDFKVRFINQGDPQALTEALSLKPKLIWVETPSNPLLRVVDITNICQQAEAVGAQVAVDNTFLSPILQLPLTLGADFVVHSTTKYINGHSDVVGGVLISKDSQQAEDIAWWANCIGATGAAFDAYLTLRGLRTLAPRIRLHEENAQAVMGFLQQHPLIGPLYHPSLPEHPGHEIANKQQLGFGSMLSFEFAGSFEQLQCFVKALTLFSLAESLGGTESLIAHPASMTHRAMSDEAQQEAGITSQLLRLSVGLEDSRDLIADLEQALSAAQRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1Q4</accession>
    <name>D0Z1Q4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ATPase involved in chromosome partitioning</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_003468</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303534.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003468"/>
    <dbReference type="EnsemblBacteria" id="EEZ42435">
        <property type="protein sequence ID" value="EEZ42435"/>
        <property type="gene ID" value="VDA_003468"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0489">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1184929at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ42435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="225" mass="25880" checksum="C2B4EF534679C7AE" modified="2010-01-19" version="1">MTNPWLSHEYEQIFQHIYRAHARVIILCSATKQSGCSTIALWLAQRCANQQSTLLVELDLCGAGLGYSPIEWQNTTEHHIAHSENLFILPQPRSAQSILQLRQQDQLQLYLNLWQQYYEFIVIDLGAVNNKHWRQLSACNLSKISDIAILSVALGKTTQEELLEAIDVLKKGQLPLLGCIANQFYNPSLQQKLLNSLQSYQKILPSKLFHFFEQKIKHNHFLRGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1S6</accession>
    <name>D0Z1S6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003490</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ42457">
        <property type="protein sequence ID" value="EEZ42457"/>
        <property type="gene ID" value="VDA_003490"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG50322IA">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="275" mass="31541" checksum="D7613D2952B5BF8A" modified="2010-01-19" version="1">MRRPSVLRCSHFNRVLCVQSDVGESSLSWVVKINWLCFFVGIPYLVSMVIYPLTQGDWGHVHAVWYTWQSFNTGILAFIASVFALNAVMYTEEKRRQRNFIAAKAFLPQALSELCSYFEKSSKLVNEAWDRAKDKSDHCKTPLKENCPELPVGYQQVFKDCISEASPEVAEHLAYILVRLQIHHSRMELLAKSFSADSHTIQDPLNLMAQVFALAELQGLVNQLFKFSRGTAPFDNKPLGVDNFYSCYDNWGVEIDENDDLKGFTEINHSKRWNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1S9</accession>
    <name>D0Z1S9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MSHA biogenesis protein MshJ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003493</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303599.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003493"/>
    <dbReference type="EnsemblBacteria" id="EEZ42460">
        <property type="protein sequence ID" value="EEZ42460"/>
        <property type="gene ID" value="VDA_003493"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3167">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2020115at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043683">
        <property type="term" value="P:type IV pilus assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043107">
        <property type="term" value="P:type IV pilus-dependent motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007445">
        <property type="entry name" value="PilO"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04350">
        <property type="entry name" value="PilO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="211" mass="24006" checksum="0874C2290E5A1398" modified="2010-01-19" version="1">MIQWQQLDQKFAALSLREKWLITGCGFVAIFFVGIFTFIQPLMADADSAHLSTLDVKNQVITANNQVIVLNNKLKEDPDAKINVNIAKLQHQETQLKLELDKKIDSLITPQQMPALLEHVLQQSASLHLVSMESLSPIQLTAGKDVGYYIHPVRLTFTGRYFDVIGYLAQLEALPVKYYWRFLDYRVEKYPEATISLEVYTLGESKDFIGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1T2</accession>
    <name>D0Z1T2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MSHA biogenesis protein MshN</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003496</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303608.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003496"/>
    <dbReference type="EnsemblBacteria" id="EEZ42463">
        <property type="protein sequence ID" value="EEZ42463"/>
        <property type="gene ID" value="VDA_003496"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1438690at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="388" mass="42629" checksum="00B364959AE0633B" modified="2010-01-19" version="1">MSSINKKLDALAQKQALSSDLPPLKMAKIKPVAQSVWPSRIAVALCAMGVFASGWIIRSSYIDADESGAGFHVVTPAVAASNPVSNHQVMVNEKSDSQSVLHSQELKTSSEENNEITTEHRSISTEAIVQVEEPKTTPIKLKHQALKPVVEEYDSAPEPEFEPEPEVHIAQVRSAPRHVIEESHEPEQLSIKTVTLNNRQLADLEYNRAEKALAQADSQQAIISLQKAVKYRPDWIEARQKLAATLYGQGSVRGAIATLEEGLELAPQQPVLRLTLAKLLAQESQPEAALAILNSVPANAPMPYLVMRGALAQEVKNNAIALNSYQQLLNRQPQNGRWWLGLAIAAERSNNKAKATMAYQQALKYGHISQQSIQFAQQRLALLTKTRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z211</accession>
    <name>D0Z211_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001858</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298829.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001858"/>
    <dbReference type="EnsemblBacteria" id="EEZ40826">
        <property type="protein sequence ID" value="EEZ40826"/>
        <property type="gene ID" value="VDA_001858"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5032S61">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1923832at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="193" mass="22440" checksum="17E0CB0981DEABF5" modified="2010-01-19" version="1">MNQDEYFSVHYDLKINVYPLEDGVTLPDHQTFVKEIPPLFRVASECSEQEEQAERLLKGISQDENAAIVQYLFAQNSKINLLLSYVLSQQDDAKHRFYTTSFGASKLNYIATQPLAVNQYVQTTLFLDYPPAAIYSYAQVSRCELLANNQFEVELRYVRLQEEDKDLLIRAALHQQQKLLRQRAQQRSNTIKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-06-02" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z254</accession>
    <name>D0Z254_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001790</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40758">
        <property type="protein sequence ID" value="EEZ40758"/>
        <property type="gene ID" value="VDA_001790"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3152">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008523">
        <property type="entry name" value="DUF805"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05656">
        <property type="entry name" value="DUF805"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="46" mass="4946" checksum="57F58F62B7ED8457" modified="2010-01-19" version="1">MLIGIIPLIGAIVLIYFFVQDGQAGSNRFGPDPKNNDNNKDGILSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z297</accession>
    <name>D0Z297_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000548</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304689.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000548"/>
    <dbReference type="EnsemblBacteria" id="EEZ39528">
        <property type="protein sequence ID" value="EEZ39528"/>
        <property type="gene ID" value="VDA_000548"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5033GKT">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1303102at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018835" evidence="1">
        <location>
            <begin position="26"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="276" mass="30676" checksum="B8F600DE1F40B521" modified="2010-01-19" version="1">MENKKTLLTASILAAGLLSSSVTFADNKKEDAPDPADVTKVVTSFKLSAGTNSNNNDFALEGELKIGGSFNPDNNFLTMISVTGAEKEEDPFEDGFDLREMRARWFQVFGTGLAGLPKAGYSLDFIDRSNDDSDVIDNIIAVGGIVKVPVLSNWVIYPNIAVVQANVKDEYKLAGTDDGIGIQVNLYNAIYLSKKGTYMMFSPQYSYLDFDGYVTQDLLLETTLGTPITENRRWWFNVTYKETFSDLSSDISSMPDKSMYANDDKRQFRAGVTYYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2D5</accession>
    <name>D0Z2D5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000586</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304780.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39566">
        <property type="protein sequence ID" value="EEZ39566"/>
        <property type="gene ID" value="VDA_000586"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="190" mass="22347" checksum="87E4810020B72C83" modified="2010-01-19" version="1">MTKLSHYIFLLSTSTFTYSASLDVIKESGDDLIINNHIFEGIIRDYQNDYVYLDYWDNKYAIIRETDSSNKERAIMTINAKNNTIDCIYQSFYTTYTHIRLGRAVCNLDLNINDFEQYQNIMGKYNIDTLSYDNPLIIDGLKLSRIELDNFIFLKNKKIKYDDIFLMYDNDKKISSIVIEENNKVSILSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2E2</accession>
    <name>D0Z2E2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GGDEF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000593</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304810.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000593"/>
    <dbReference type="EnsemblBacteria" id="EEZ39573">
        <property type="protein sequence ID" value="EEZ39573"/>
        <property type="gene ID" value="VDA_000593"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2199">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="2">
        <location>
            <begin position="164"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="289" mass="32669" checksum="83AF673C13E64BB5" modified="2010-01-19" version="1">MGTLSQLSTRLISIVCISILVAAFFISSGTLSVVTSILTLVLIIMLLLEDFGKAMKLPLILALILYGFGVAIEILNQVPELREHPVLKNTDTVFVHLGVFMICFCLIKLLHQRHSLIKKLNIQINKAKQLEGELSKQALQDDLTLLGNRRALFRRFDQLVLKHEKGMLAYIDIDNFKQVNDMMGHKSGDHVLVQIAKILVKTAPIGSHYYRIGGDEFVVLFPTDDEKHIRDWIDTLYQQTEELCQYYSINLSVGLAPYHQGNLSDPDSILVQADSAMYLDKSKKKISMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2E6</accession>
    <name>D0Z2E6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribosomal RNA large subunit methyltransferase F</fullName>
            <ecNumber evidence="2">2.1.1.181</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">23S rRNA mA1618 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">rRNA adenine N-6-methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rlmF</name>
        <name evidence="4" type="ORF">VDA_000597</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Specifically methylates the adenine in position 1618 of 23S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>adenosine(1618) in 23S rRNA + S-adenosyl-L-methionine = H(+) + N(6)-methyladenosine(1618) in 23S rRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:16497"/>
            <dbReference type="Rhea" id="RHEA-COMP:10229"/>
            <dbReference type="Rhea" id="RHEA-COMP:10231"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74449"/>
            <dbReference type="EC" id="2.1.1.181"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the methyltransferase superfamily. METTL16/RlmF family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.181" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304818.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000597"/>
    <dbReference type="EnsemblBacteria" id="EEZ39577">
        <property type="protein sequence ID" value="EEZ39577"/>
        <property type="gene ID" value="VDA_000597"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3129">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1027015at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052907">
        <property type="term" value="F:23S rRNA (adenine(1618)-N(6))-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01848">
        <property type="entry name" value="23SrRNA_methyltr_F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010286">
        <property type="entry name" value="METTL16/RlmF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016909">
        <property type="entry name" value="rRNA_lsu_MeTfrase_F"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13393">
        <property type="entry name" value="PTHR13393"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05971">
        <property type="entry name" value="Methyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029038">
        <property type="entry name" value="Mtase_YbiN_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="1 2 4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="332" mass="37017" checksum="DE913B74D617354E" modified="2010-01-19" version="1">MSSKKQTTPKKGLHPRNPHRARYDFPQLTKALPELSQFVAKNPYGDLSVNFSDPMAVKALNKALLKHFYQVDFWDIPDGFLCPPIPGRADYLHYIADLLAASNNGKIPQGKRIKGLDVGVGANCVYPIVGHRVYGWQFAAADIDPISIKSAKFIVESNASLKGQIQLRLQKDANCIYTNMIKPTDLFDFTMCNPPFHSSLEEATAGSERKVRNLAANTKKRTGIKVDANNNNSKPVLNFGGQKAELWCPGGEAAFIQRMIKQSAEHSAQCLWFTTLVSKKETLPLVYQALKEIKAADVKTIEMSQGQKITRIVAWTFLPEKAQQAWAKARWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2E8</accession>
    <name>D0Z2E8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Predicted membrane-associated metal-dependent hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_000599</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304831.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000599"/>
    <dbReference type="EnsemblBacteria" id="EEZ39579">
        <property type="protein sequence ID" value="EEZ39579"/>
        <property type="gene ID" value="VDA_000599"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2194">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1067869at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008484">
        <property type="term" value="F:sulfuric ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016772">
        <property type="term" value="F:transferase activity, transferring phosphorus-containing groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012549">
        <property type="entry name" value="EptA-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040423">
        <property type="entry name" value="PEA_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30443">
        <property type="entry name" value="PTHR30443"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08019">
        <property type="entry name" value="EptA_B_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="73"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="111"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="153"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="EptA_B_N" evidence="9">
        <location>
            <begin position="54"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="8">
        <location>
            <begin position="236"/>
            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ39579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="557" mass="63696" checksum="7CB3BF96FC0EA336" modified="2010-01-19" version="1">MIKPSLSYSKLILLLAIYFGLVLNIPLYKELYYLTRNQAVIHWGFLVSIPIFVISALNLLFQLFAWPKITKPFFALLLLLSSIISYASFQYRTIFDSEMLRNLMQTYSGEAFAYISMSSIVWIIAFGVFPTLVLFMTHIKPVNNLWVFIQHKLLSMGASALLVIIISGFFYQDYVSLGRNHSEVRRLIIPTHFVYSANKYIKQTYFSPPMVYREIGTDAKQTDKALARAKEKPSLVILVVGETARAQNYQFNGYHKATNPFTSQQDVIFYPNVSSCGTATAISVPCMFSALNRDNYNHDIANNQDNVLDVLKRANIDILWKDNDGGDKGVARHVTYREIKPNVNNLNCNGSSCFDIALLGNLDKEIDNMQGNRLVVLHLIGSHGPTYYQRYPKSHEIFTPVCARADIEKCTREEITNTYDNTIAYTDYVISQLINQLKAKGSSYNTALLYLSDHGESLGEHGLYLHGMPYQLAPRYQTEIPMMLWLSQSFSTENNLDPNCLEEQAKLYHYSHDNLFHSLLGLFSVRSEVYNKRQDIFAQCQNRLPIDYNKLQQSDSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2F5</accession>
    <name>D0Z2F5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amine oxidase flavin-containing</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000606</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304847.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000606"/>
    <dbReference type="EnsemblBacteria" id="EEZ39586">
        <property type="protein sequence ID" value="EEZ39586"/>
        <property type="gene ID" value="VDA_000606"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2907">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="630753at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amino_oxidase" evidence="1">
        <location>
            <begin position="10"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="435" mass="49968" checksum="6AAA617EC6077C3B" modified="2010-01-19" version="1">MKIAIIGSGISGLTCAWYLQKQHQVSLYEANDYLGGHTATVDVEVESGHYAIDTGFIVFNDRTYPNFERLLKELDIKGQDTQMSFSVHNQQSGLEYNGHTLATLFAQKANLVNPRFYRFLYEIVKFNREAKKAIERQDFDSSQTLGDFLNQYGFSDYFCTNYILPMGAAIWSSTLSDMRKFPLLFFLKFFLNHGLLDITHRPQWKVIPGGSRQYINKMLLDLKADIRLNTPVLTVHRFHDRADVVIKNREQPELHQIESFDQVIFACHSDQALAMLAKPSINEKEVLGNIYYQDNEVVLHTDTNLLPIEPKAWAAWNYHLFPASEHGSERLAALTYNMNILQGLQSSETFCVSLNQTEKIDPTKILRTFTYSHPVFSTQSIAAQQKRHDINGFQRSWFCGAYWYNGFHEDGVRSALDVIEAINELPSQSNYQRSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2N0</accession>
    <name>D0Z2N0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">HTH-type transcriptional regulator MalT</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">ATP-dependent transcriptional activator MalT</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">malT</name>
        <name evidence="8" type="ORF">VDA_000681</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides. Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box.</text>
    </comment>
    <comment type="activity regulation">
        <text evidence="6">Activated by ATP and maltotriose, which are both required for DNA binding.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Monomer in solution. Oligomerizes to an active state in the presence of the positive effectors ATP and maltotriose.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the MalT family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305045.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000681"/>
    <dbReference type="EnsemblBacteria" id="EEZ39661">
        <property type="protein sequence ID" value="EEZ39661"/>
        <property type="gene ID" value="VDA_000681"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2909">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045913">
        <property type="term" value="P:positive regulation of carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045893">
        <property type="term" value="P:positive regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01247">
        <property type="entry name" value="HTH_type_MalT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041617">
        <property type="entry name" value="TPR_MalT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023768">
        <property type="entry name" value="Tscrpt_reg_HTH_MalT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17874">
        <property type="entry name" value="TPR_MalT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0010">Activator</keyword>
    <keyword evidence="2 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="7">
        <location>
            <begin position="832"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="39"/>
            <end position="46"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ39661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="902" mass="103674" checksum="1155E4E01DC887B9" modified="2010-01-19" version="1">MWIPSKLTRPARLYNAILRPRLLATLEHAPFYRLVLFRSPAGYGKTTMAAQWLSEHPTTGWLNLDDNDNDTFRFANYLIQALNRGTSDAAPKTQAMAERRQFACLTTLFGELFAEIADYQQQTYLVLDDYHVITNEDIHDGMRFFLKHMPDNLTLVLTSRTQPPLNTANLRVRDQLIEVDNEWLAFDEEETERFFGQRIKADVEPQVLHTLHSQVEGWPSALQLIALHAQQKPQHLAQSALSMAQFNRGHLWDYLAEEVFDQLDDETQQFLLQCSVLDTFNAVLVTELTGYCDSLAKLESLNRFGLFLTTLDSDDNWYRFHNLFAEFLNHQRHSRLPEQQDHLHTLAAQAWLKQNSPQQALAHALKGQNEQLTVDIIVEHGWKLFHHGELKLLEGAISALSRDALFSTPRLALLRAWLAQSQHQYDDVGALLNEAEIEMTHRNITLDDGLQGEFNALRAQVAINQNNPQEALELSELSLGQLPSNTYRSRIVATSVVGEVHHCIGNLNRALPMMQQTEKLARQYHVYHQALWALIQQSEILVAQGYVQAAFELLEQAFKLIREQHLQQVPLHEFVLRLKAQILWCWNRLDEAEECAQKSLDVLAPFEDNYSLHAYSMLARIALTRGELDKAARYLTLCDELMERSAFHIDWRANSEFSSLLYWHQKGEITAIEHYLVKAEQPQQACNHFQQLQWRNIARANMYLGHYQQALDIMNMLDAACQQHNLVTDNNRNLVLEAVIYKQMGNKEVALSKLKNALLLTNNTGMVGNFLCDAEIVAKLLDELIQKQHLSDLALYRAQQLLREMNNKERTRSVHFDEDFVEKLLTLPNIPELIRTSPLTQREWQVLGLIYSGYSNEQIASELDVAATTIKTHIRNLYQKLGIANRQEAITTAEELIGLMGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2T3</accession>
    <name>D0Z2T3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Cobyric acid synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">cobQ</name>
        <name evidence="10" type="ORF">VDA_000734</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Cofactor biosynthesis; adenosylcobalamin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the CobB/CobQ family. CobQ subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305199.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000734"/>
    <dbReference type="EnsemblBacteria" id="EEZ39714">
        <property type="protein sequence ID" value="EEZ39714"/>
        <property type="gene ID" value="VDA_000734"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1492">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="744477at2"/>
    <dbReference type="UniPathway" id="UPA00148"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015420">
        <property type="term" value="F:ABC-type vitamin B12 transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01750">
        <property type="entry name" value="GATase1_CobQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00028">
        <property type="entry name" value="CobQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002586">
        <property type="entry name" value="CobQ/CobB/MinD/ParA_Nub-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033949">
        <property type="entry name" value="CobQ_GATase1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004459">
        <property type="entry name" value="CobQ_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011698">
        <property type="entry name" value="GATase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21343:SF1">
        <property type="entry name" value="PTHR21343:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01656">
        <property type="entry name" value="CbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07685">
        <property type="entry name" value="GATase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00313">
        <property type="entry name" value="cobQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="5 7" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CbiA" evidence="8">
        <location>
            <begin position="8"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="GATase_3" evidence="9">
        <location>
            <begin position="255"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="7">
        <location>
            <position position="334"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ39714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="492" mass="53399" checksum="BC69F13EF89B1EEB" modified="2010-01-19" version="1">MQKTTQAIMVQGTTSDAGKSVLVAGLCRVLARKGIAVAPFKSQNMALNSAVTQDGGEIGRAQAVQAQACRIEPTVDMNPVLLKPNTDIGAQVIVQGKALADMDAVGYHNYKKVVMGPIMDSFAKLQAQYQTVVIEGAGSPAEINLRENDVANMGFAEKADVPVIIIADIDRGGVFAHLYGTLALLSESEQNRVKGFVINRFRGDIKLLESGLDWLEQKTGKPVLGVLPYLHGLMLEAEDAINSQQVESTTDQPLRVAVPVLTRVSNHTDFDPLRMHPQVNLMLVGKGEALPPCDLVIIPGTKNVRDDLAYLKEQGWDQQIQRHLRLGGKLMGICGGYQMLGQTIADPLGIEGKAGESQGLGYLDVTTVLEQEKQLKQVSGILTLPNQASVPVRGYEIHAGVTTGVQVDAPIQLESGLDGQLGLDNQVFGTYLHGVFERQEACDAILSWAGLEATQTPDFDQIREQGIDRVADTIEQYLDLEALWPEWDLFKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2Y2</accession>
    <name>D0Z2Y2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 11">Glycogen synthase</fullName>
            <ecNumber evidence="5 11">2.4.1.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 11">Starch [bacterial glycogen] synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">glgA</name>
        <name evidence="14" type="ORF">VDA_000783</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 11">Synthesizes alpha-1,4-glucan chains using ADP-glucose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>[(1-&gt;4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1-&gt;4)-alpha-D-glucosyl](n+1) + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18189"/>
            <dbReference type="Rhea" id="RHEA-COMP:9584"/>
            <dbReference type="Rhea" id="RHEA-COMP:9587"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15444"/>
            <dbReference type="ChEBI" id="CHEBI:57498"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.4.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 11">Glycan biosynthesis; glycogen biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.21" evidence="5 11"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305337.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000783"/>
    <dbReference type="EnsemblBacteria" id="EEZ39763">
        <property type="protein sequence ID" value="EEZ39763"/>
        <property type="gene ID" value="VDA_000783"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0297">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="83240at2"/>
    <dbReference type="UniPathway" id="UPA00164"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033201">
        <property type="term" value="F:alpha-1,4-glucan synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004373">
        <property type="term" value="F:glycogen (starch) synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009011">
        <property type="term" value="F:starch synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005978">
        <property type="term" value="P:glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00484">
        <property type="entry name" value="Glycogen_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011835">
        <property type="entry name" value="GS/SS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013534">
        <property type="entry name" value="Starch_synth_cat_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08323">
        <property type="entry name" value="Glyco_transf_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02095">
        <property type="entry name" value="glgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11" id="KW-0320">Glycogen biosynthesis</keyword>
    <keyword evidence="7 11 14" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_transf_5" evidence="13">
        <location>
            <begin position="13"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="12">
        <location>
            <begin position="300"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="26"/>
        </location>
        <ligand>
            <name>ADP-alpha-D-glucose</name>
            <dbReference type="ChEBI" id="CHEBI:57498"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00019935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEZ39763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="505" mass="57011" checksum="99B66619AE5A1A43" modified="2010-01-19" version="1">MVSKRKPAGKALKILFVASEVDGLVKTGGLADVAKSLPATLKSMGHDVRIVLPFYQTIKHSDEATECAKLKLHVETQPEPVFYRVMDMNVAGVPVWALDVPHYFARPEIYAENNVEYADNGERFSFLAAGALDCCQQLGFQPDVVHCNDWHTGLIPFLLKTRYRQSDFFANTRSVISIHNAVFKGVYNYDQFSLIPELIQHRYLNLEQDRAHISMLKAGVAYADRINAVSPNYATELLTDLGSHGMGWEFQQRARDLFGIVNGCDYDDWNPETDGFIKQKYKANKVSLVRGKKACKRDLQQQVGLPEDDVPVYGMVCRLTEQKGIHYLVPILQDFLLNEVQVVIVGTGDPRLAEQLRQISLANPTKCVFVEAYSNPLAHCVEAGSDFFMMPSEFEPCGLNQMYSLAYGTLPIVRAVGGLKDTVIDYDATPKFATGFIFTQPTPEALLIKLQRSLLLYCQQPQEIKRLQQNALACKFSWQESAQQYLDMYRSMWAKQSETKMEQEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2Y8</accession>
    <name>D0Z2Y8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TPR domain protein putative component of TonB system</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000789</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000789"/>
    <dbReference type="EnsemblBacteria" id="EEZ39769">
        <property type="protein sequence ID" value="EEZ39769"/>
        <property type="gene ID" value="VDA_000789"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019358" evidence="1">
        <location>
            <begin position="26"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="392" mass="44525" checksum="2B96A4689838B4C7" modified="2010-01-19" version="1">MMKIKKPLVSVLLLSASILPCWVQAAPQLSQSVAAKLQKANTLMQEDKLTQASQLLTSIAVDKAYDKAFIARMLGVVYWQQGKAQSAIKALTQAVNSGLLKDEYGWQTERMLADLLLSEQQYNKALPHYYSLTQVKAKGNKTDEVWLRIAQSHYQLSQWSKVLTSIKRYDSYGNKDSVSPLSIALGAQLQLKKYNLAVPTLNRLIALEPNKNIWWQQLASLQIRIGKTSDALDTLVLAQYQGIQLSNNELLTLAQLYAQRGIPERSAKIIATLSDANTQERLVEQANYWQMAREWDKAITVWKKAVSLNSKYRWQLAQLQLQQGQYQQALSQLNQISNSKYQSQVELAKVRAYYKLDKLEKAIIHAKMANNLKPSQEAKGWIQYLSQMQTMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z343</accession>
    <name>D0Z343_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000844</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305507.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000844"/>
    <dbReference type="EnsemblBacteria" id="EEZ39824">
        <property type="protein sequence ID" value="EEZ39824"/>
        <property type="gene ID" value="VDA_000844"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5032QN7">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1157527at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="188" mass="21989" checksum="FA28C7D8FF0E5C6D" modified="2010-01-19" version="1">MTPFSQINMVRSQQIYATFVNGKVITKQIYDLYQQSFLESPLYTELYNHLDHFTQLYLHIGYTLNFNVEGEFFYISRSEAEEDADTNATKIQAMLLIIARYWVDKGYDLDDLLTPVIGLGRTALEEIAEQTIYDDIRQALGIETWDKALNYLADRNFLYQCGDKHYILSSAGMHFLNLHVEKYTHEQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-02-10" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z370</accession>
    <name>D0Z370_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000871</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305586.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39851">
        <property type="protein sequence ID" value="EEZ39851"/>
        <property type="gene ID" value="VDA_000871"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502ZTSF">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1528399at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021422">
        <property type="entry name" value="DUF3069"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023132">
        <property type="entry name" value="Sama2622-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11269">
        <property type="entry name" value="DUF3069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158675">
        <property type="entry name" value="SSF158675"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="150" mass="17349" checksum="876C63F9BF12CF05" modified="2010-01-19" version="1">MSDIEKKDEQVIEEVQFTLDDCSPELRKIIEVEEVPAELHDMLINVYKVSEPTTLEVWNALPKSAQNVLDNFEQFHALVALSQTYSGVDFLGEMQETEFPEDMGAEEQANYKATMLDKVLHNCVKDLAKQLKKARQNPPMKREFQEIFKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z392</accession>
    <name>D0Z392_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative NupC family protein (Permease)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000893</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39873">
        <property type="protein sequence ID" value="EEZ39873"/>
        <property type="gene ID" value="VDA_000893"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1972">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005337">
        <property type="term" value="F:nucleoside transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008276">
        <property type="entry name" value="C_nuclsd_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011657">
        <property type="entry name" value="CNT_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011642">
        <property type="entry name" value="Gate_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10590">
        <property type="entry name" value="PTHR10590"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07670">
        <property type="entry name" value="Gate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07662">
        <property type="entry name" value="Nucleos_tra2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="197"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="236"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="290"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="326"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="Gate" evidence="3">
        <location>
            <begin position="39"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleos_tra2_C" evidence="2">
        <location>
            <begin position="141"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="351" mass="36488" checksum="482FEA7379300055" modified="2010-01-19" version="1">MLGAMSDGVAGLLSFADVGIQFVFGDLSNIQKSGFVFAIRVLPLVIFISALISLLYYLGVMQWIIKVLGGGIQKALGTSRAESLVATGNIFLSQGESPLLVKPFLSQMTRSELFVVMTCGMASVAGSVLGGYAGLGVDLKYLIAASFMAAPGGLLMAKILVPETGTPVEQTAIEMEKSDHSNAIDALAAGAMNGMKVSVAIGTMLIAFVSVIAMVNAGLESVGEMFGFAGMTMQKVLGYVFSPLAFVAGVPAHEMLKAGSFIGEKLILNEFVAFMDFANVKQTLSEHTQVIITFALCGFANIGSIAIQIGSIGAMAPDRRSDVANLGFRAVLAATLANLMSAALAGIFISL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3A8</accession>
    <name>D0Z3A8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000909</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000909"/>
    <dbReference type="EnsemblBacteria" id="EEZ39889">
        <property type="protein sequence ID" value="EEZ39889"/>
        <property type="gene ID" value="VDA_000909"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="440" mass="50206" checksum="27CB6083128B6C8D" modified="2010-01-19" version="1">MVIDTRGFMDGALRGFDLMENHYDRAERKADRERSLRLADEQNKRQEQWRQKAWDRDEDRYQERLKTDQANNDKEERRYQDGLKLKKQQLAQSNAVNAAQQQYYQQRNNREKRLQFIQDNAPLIDQAWTRFNETGELSDILNNDYIKGTAYDVRSYTPDKINAFNNLRTNIPNVLSGKADVDSLVPDIGVVYKSNIDRVIGSKDDSGKRTVTGAELANIHLASDINPDIKGDQPGLVLGLKVKYDDGSTAVKPVTKLRSSDPNDHPLVIPLDEAMKDLSGQMKLARLASTSKAYQQLFGKDNKAQKSVDKEYRGEVNKISKWYGDATLDLMKNSGGTVSPEQQEQLDKQRDDMLAKLNKMYGKAQTTTITKFTPTERWASGDGTKQEYLQAMKSAGRDIGSLSVEQLEQGYQQALIRKKEREKEQHESEIANRIRGGIVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3B9</accession>
    <name>D0Z3B9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000920</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000920"/>
    <dbReference type="EnsemblBacteria" id="EEZ39900">
        <property type="protein sequence ID" value="EEZ39900"/>
        <property type="gene ID" value="VDA_000920"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="51" mass="5789" checksum="7C803E6953426C67" modified="2010-01-19" version="1">MIADSQRYTNAKTQAETGKILTEMERVNQEVEQIKQGLLANLQQQINSIVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3K4</accession>
    <name>D0Z3K4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">OMP_b-brl domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001005</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305963.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39985">
        <property type="protein sequence ID" value="EEZ39985"/>
        <property type="gene ID" value="VDA_001005"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031N4X">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027385">
        <property type="entry name" value="OMP_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13505">
        <property type="entry name" value="OMP_b-brl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018814" description="OMP_b-brl domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="OMP_b-brl" evidence="2">
        <location>
            <begin position="58"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="240" mass="26317" checksum="2C431FE93888982C" modified="2010-01-19" version="1">MKKIMLATSTLVAILSQSAVAETLDQQSSILPVNTDSGSELTESVQVPSFDDSRHYFVGLTGGLSQFSITNRAKISGQSFDAPSPDRNGFAGIDFGIYAPNGKGRIYYSYQRHQADTKVNDVKALENTIDLHLLSGDYLFRPHKAISPFVGAHFGYTQVDGKATGEGRYHESGYVFGLQAGVSWRITQQFTMDIGARHTVLPSEAVKKWTGKISGDNHSVSFETQPESISSVYMAVNYRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3M1</accession>
    <name>D0Z3M1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001022</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306005.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001022"/>
    <dbReference type="EnsemblBacteria" id="EEZ40002">
        <property type="protein sequence ID" value="EEZ40002"/>
        <property type="gene ID" value="VDA_001022"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502Z8XA">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1554094at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025130">
        <property type="entry name" value="DUF4056"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13265">
        <property type="entry name" value="DUF4056"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018878" evidence="1">
        <location>
            <begin position="23"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="359" mass="39807" checksum="B7D45F9BCD3131FE" modified="2010-01-19" version="1">MIKLIKLILGAGLLLFIGSVNAMDAPVGVRPCCAFGKDLKAEVGGVPVPFFSIGNILGIEDLGSHVYNDGSQGVSSSLLGMGKETNGIVYTQKGGFIDIAHVRDTADFTFYLYQEIHSKLGSGTSIVLTPELRSRHVYLPKKDTHSLTAQERQQISVELAGLMAFRLAQWHEIAQWFGLESVGGFSELASAFSPEDLYSNMLGAKVAMNILQQQPSISKQTFSQIFTQNLKAKLIALDIVSADKAKQKMASLDGQWWDSSKRLPQKWVVLKRDYRLRLDLQPNGVANGELEQLTAQLSNGDNSEQWTDLYLHSADREKQFELLPAELKKKQVWQPKDFNQLADFAKQHDAKEVGHSTQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3N9</accession>
    <name>D0Z3N9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Isoaspartyl aminopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001040</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306057.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40020">
        <property type="protein sequence ID" value="EEZ40020"/>
        <property type="gene ID" value="VDA_001040"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1446">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="890789at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000246">
        <property type="entry name" value="Peptidase_T2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10188">
        <property type="entry name" value="PTHR10188"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01112">
        <property type="entry name" value="Asparaginase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018883" evidence="4">
        <location>
            <begin position="22"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="236"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="259"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="208"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage; by autolysis" evidence="3">
        <location>
            <begin position="207"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR600246-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR600246-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR600246-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="341" mass="36225" checksum="24EA17D7E41E95FC" modified="2010-01-19" version="1">MKLKTLSIAILSATFSLSSFAEESPIRLVIHGGAGTITKETITPEKEQQYQQKLSEALQAGYAVLNKGGSSLDAVMASINVMEDSPLFNAGKGAVFTHDGKNELDASIMDGKTLMAGAVAGVTNIKNPINAAHIVMTKSPHVLMVSKGAEKFAAENGIQTVDPSYFKTDFRWQQLQKAIEKEQVVLDHDGKTAALFVDPMMYDYKYGTVGAVALDKEGNLAAGTSTGGMTNKRYGRVGDSPLIGAGNYADNETVAVSATGSGEKFIRTLTAYNIASQVKYKGVSLQEAAKNALDDVKSIDGSGGVIVLDKQGNYTMEFNSAGMYRGTISNDGIPHVAIYKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3T9</accession>
    <name>D0Z3T9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hypothetical maturase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001090"/>
    <dbReference type="EnsemblBacteria" id="EEZ40070">
        <property type="protein sequence ID" value="EEZ40070"/>
        <property type="gene ID" value="VDA_001090"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3344">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030931">
        <property type="entry name" value="Group_II_RT_mat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013597">
        <property type="entry name" value="Mat_intron_G2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08388">
        <property type="entry name" value="GIIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04416">
        <property type="entry name" value="group_II_RT_mat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="348" mass="40484" checksum="DC0A1011838CD3FD" modified="2010-01-19" version="1">MLGIPSVRDRVVQQTLNDLLTPIFEEQFHPSSFGYRPRRSCHDAINKATMFIRRYGMRHVVDMDLSKCFDKLDHELILTSIKKRITDSSILELIKQFLQSGVIANGEWHVTEIGSPQGGVISPLIANIYLDAFDQEMRKRNHRIVRYADDILIFCRSRRGAENALKQARKILEHDLKLKVNQEKSHIAHSAEGVKFLGVEIGSNYTRIQPKKIKGFKRKLKQMTRRNSGKPLTMIIDALNPVLRGFGQYFKIANTSREFKSLVAWLRRRLRSIQLKLWKKPMKLHRRLKQLGYKPPFQFIKMNSWKNAASPLASYAMPNQWFVDLGLVNLGHIKTGYVFSNYAEWKYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3U5</accession>
    <name>D0Z3U5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ricin B-type lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001098</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306213.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40076">
        <property type="protein sequence ID" value="EEZ40076"/>
        <property type="gene ID" value="VDA_001098"/>
    </dbReference>
    <dbReference type="OrthoDB" id="447059at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00161">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00652">
        <property type="entry name" value="Ricin_B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="SSF50370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018824" description="Ricin B-type lectin domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B-type lectin" evidence="2">
        <location>
            <begin position="104"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="275" mass="30575" checksum="36753BB01C3A4CE4" modified="2010-01-19" version="1">MIKNIILVSCVMMSANAMAGLSEYASNLDKTTFKFKVGKENKPGKFNCVTIAGGSELGNPYFNGQDVVAHKCSEEEKDTQFYSYINGEIKAVINTFPSTYVSHDYCIDVDNGIDVPGNKVQLFECNGSKAQKFTPYTTNKDQVVFKTNAKNCLSISENGAEVRACDLEDNTQLFDAVNPKKMIRVDFYDGAGFNMLGRVEDKGLRTFYSPKKMMLGQDRTVYMPGTSKTVKISGIGLYAGASTYSKWVDTKPGEHFRLQSWGTLFNPQYEVSKIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z405</accession>
    <name>D0Z405_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AAA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001158</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306373.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001158"/>
    <dbReference type="EnsemblBacteria" id="EEZ40136">
        <property type="protein sequence ID" value="EEZ40136"/>
        <property type="gene ID" value="VDA_001158"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1401">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4372">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="489714at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011704">
        <property type="entry name" value="ATPase_dyneun-rel_AAA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07728">
        <property type="entry name" value="AAA_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="2">
        <location>
            <begin position="526"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="313"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="835" mass="94078" checksum="EBB6946F1F0048A4" modified="2010-01-19" version="1">MQEKKALNKLVVIKSGQLNENQGFITPILSISDNEEFIPISVHDYPQDILVSKGYPYIDTNYESNELFILKSHNLDEEKTLQSGSPRYWTRDESAFSDLTPSTLLPILSVSLPSKENGILPTGVTPPTRPFFILDNGHLYGPLTSSQTDDDRYIVEPYVHPSLSFGRGYIGRFPISDITNCLVETRINDELVLYVSSFKQLSSHRKDKTSIDYVSDDQLIKVVNQLGFGKQTKGLGKKEAERLQQIIADSEKANKFGKQDERLERLKGLLDRYLSEADIGFELVKNYLDSNSGQAFLNNYVEVNKSTLLSDFIDKVKADAKAEEKKIQQKLQEQKAQITAKEQEITQIIENVALKRKEAQDEIKRIAAETEDEVRQTLKLKQQELSENIATLENEQNSLEKQIKEKVQHLELVNEIEKLKDECNYYEKHSKRLESTVKGFEATLKNNDTEELAKKIGEMEAINRVLNGKSASVSKPVQRYNPITFSESEPDSAEQVIDAIGAHFAQDNGRMFSKEEMTNLIVSVNQSFLTILSGPPGTGKTSTVTRLAKALHLGSSRGDQNFLYVPVGRGWVSSRDTLGFYNSLKDVYQESRTGLYSFLSRQESKDSDALKLILLDEANLSSMEHYWSDFLALCDLENLNRPIDTGIPHESHRFLKVGDSTRFIATINNDATTEKLSPRLIDRVPVITLDSPTDKIVETTSLVLDGSVRASKLRELFIPEYAELSKADESILAKIIDTLSTRDPIFGKSIPISRRKVNAITNYCDVAGQMIGSEAAMDFAIQQHILPHIEGYGASFRKRLEQLLTIVNKTYPRSAAQIERILASGNEFTGSYSYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z425</accession>
    <name>D0Z425_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Formate hydrogenlyase transcriptional activator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_000281</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303934.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000281"/>
    <dbReference type="EnsemblBacteria" id="EEZ39263">
        <property type="protein sequence ID" value="EEZ39263"/>
        <property type="gene ID" value="VDA_000281"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3604">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="123059at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002197">
        <property type="entry name" value="HTH_Fis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025943">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025944">
        <property type="entry name" value="Sigma_54_int_dom_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02954">
        <property type="entry name" value="HTH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00158">
        <property type="entry name" value="Sigma54_activat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00676">
        <property type="entry name" value="SIGMA54_INTERACT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00688">
        <property type="entry name" value="SIGMA54_INTERACT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50045">
        <property type="entry name" value="SIGMA54_INTERACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="6">
        <location>
            <begin position="382"/>
            <end position="611"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="739" mass="83930" checksum="36D24E345044181F" modified="2010-01-19" version="1">MLEFLFAIRANLSARANGTMERFEADLMSFSKALLSINDISGVMTFLNNEDLLFIQVDRVNLLLKNNIDDTPTLYFLDNGNEQKNYQYNQHSLALHKIASCEYYHDISGHELYQTFPQLVDHPAYYDVNRYCKIPLLIAGKPLGAIEYINHKLADSIESERQFKLFNNMIAAMIEHIIEHQLASDFTQQLSNEKKNFQVLVDITNTVISQSTKKELISSLLHFLYQHFAMTELSIIQLQDNHYMQMFCGLNNNNTEFHCHFFNDDKMIKHAIENNKPVLLDHNQLEQIRQDENGPYFPSKVKSACIVPMVFRGLTIGYICYMKRETLNYQQYDIELVQQIASRVALAMHSIKAHQATLPRTETEQYVSIEESYDEHAIFDDIISQSEAMNQVLEKVAMVASCDSTVLILGESGTGKELIARAIHKMSLRSKTRMVKMNCAAIPAGLFESELFGHERGAFTGAISQRVGRFEQAHKGTLFLDEIGDMPLELQPKLLRALQENEIERVGKNQLISVDVRIVVATNVDLLAMVDAKQFRNDLYYRLNVFPIEVPPLRQRAEDIPLLVKHFARQLAQKMGKKITAIAASDLELMQRFSWPGNVRELHNFVERSVILTRGHVLNIPVDELISLQPHIVQNSRKMESQASLSKTSLKQAQELPQVASIDDLTSSGSESVCSVDTAAKNEVKKVRPIVDQSMIINALKRCQGVIAGPNGAANMLGLKRTTLLSRMQKMGISSQDYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z446</accession>
    <name>D0Z446_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Urease accessory protein UreG</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ureG</name>
        <name evidence="6" type="ORF">VDA_000302</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303986.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000302"/>
    <dbReference type="EnsemblBacteria" id="EEZ39284">
        <property type="protein sequence ID" value="EEZ39284"/>
        <property type="gene ID" value="VDA_000302"/>
    </dbReference>
    <dbReference type="GeneID" id="57343317"/>
    <dbReference type="eggNOG" id="COG0378">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1134430at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01389">
        <property type="entry name" value="UreG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003495">
        <property type="entry name" value="CobW/HypB/UreG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004400">
        <property type="entry name" value="UreG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31715">
        <property type="entry name" value="PTHR31715"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02492">
        <property type="entry name" value="cobW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00101">
        <property type="entry name" value="ureG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 4" id="KW-0996">Nickel insertion</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="cobW" evidence="5">
        <location>
            <begin position="10"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="14"/>
            <end position="21"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ39284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="206" mass="22428" checksum="03059C136CD6D425" modified="2010-01-19" version="1">MQNYKQPLRIGVGGPVGSGKTALLEVLCKALRDRFQIAVVTNDIYTQEDAKILTRAEALDADRIIGVETGGCPHTAIREDASMNLAAVEELAMRHKNLDVVFVESGGDNLSATFSPELADLTIYVIDVAEGEKIPRKGGPGITRSDLLVINKIDLAPYVGASLEVMEADTARMRPEKPYVFTNLKEGKGLDKIIDFIVDRGMLEVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z455</accession>
    <name>D0Z455_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Oligopeptide transport ATP-binding protein OppD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_000311</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000311"/>
    <dbReference type="EnsemblBacteria" id="EEZ39293">
        <property type="protein sequence ID" value="EEZ39293"/>
        <property type="gene ID" value="VDA_000311"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0444">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1101128at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="231" mass="25486" checksum="D468173084F7335D" modified="2010-01-19" version="1">MLTIKNLSIKSSEQVLLDNFNLSVDKGELVGLIGASGSGKSILFQAIQGTLPSSFDHTGSIEFMDEAPKQTALIAQHSGVLNPNLTIGKQLHLFAGHQGDIDRYLKQLKLDLSIKEQYPYQLSGGMLKRILTCLALIQDTPYLLADEPACGLDHDNAVLLYQCLRQQNHKGVIVISHDLELLVNYVDRIVVLNKGLQVDNTTPSAILTGQCQSYTCQLWQALPQHWESCCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-06-02" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4A4</accession>
    <name>D0Z4A4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000360</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304147.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39342">
        <property type="protein sequence ID" value="EEZ39342"/>
        <property type="gene ID" value="VDA_000360"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031NJ0">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2062171at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="65" mass="7457" checksum="232566DF773250DC" modified="2010-01-19" version="1">MSINSIDHSEMASVSSKWDYKDESASRIADSKKQQAKARRRIELLRDIRESGLTLEEARELGLLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4B0</accession>
    <name>D0Z4B0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="19">Nitrite reductase [NAD(P)H] large subunit</fullName>
            <ecNumber evidence="19">1.7.1.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">VDA_000366</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 12">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Nitrogen metabolism; nitrate reduction (assimilation).</text>
    </comment>
    <dbReference type="EC" id="1.7.1.4" evidence="19"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304165.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000366"/>
    <dbReference type="EnsemblBacteria" id="EEZ39348">
        <property type="protein sequence ID" value="EEZ39348"/>
        <property type="gene ID" value="VDA_000366"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1251">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1128731at2"/>
    <dbReference type="UniPathway" id="UPA00653"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008942">
        <property type="term" value="F:nitrite reductase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042128">
        <property type="term" value="P:nitrate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.413.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007419">
        <property type="entry name" value="BFD-like_2Fe2S-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041854">
        <property type="entry name" value="BFD-like_2Fe2S-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005117">
        <property type="entry name" value="NiRdtase/SiRdtase_haem-b_fer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036136">
        <property type="entry name" value="Nit/Sulf_reduc_fer-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012744">
        <property type="entry name" value="Nitri_red_NirB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017121">
        <property type="entry name" value="Nitrite_Rdtase_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006067">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045854">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006066">
        <property type="entry name" value="NO2/SO3_Rdtase_FeS/sirohaem_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041575">
        <property type="entry name" value="Rubredoxin_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04324">
        <property type="entry name" value="Fer2_BFD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01077">
        <property type="entry name" value="NIR_SIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03460">
        <property type="entry name" value="NIR_SIR_ferr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18267">
        <property type="entry name" value="Rubredoxin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037149">
        <property type="entry name" value="NirB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00397">
        <property type="entry name" value="SIROHAEM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55124">
        <property type="entry name" value="SSF55124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56014">
        <property type="entry name" value="SSF56014"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02374">
        <property type="entry name" value="nitri_red_nirB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00365">
        <property type="entry name" value="NIR_SIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 12" id="KW-0274">FAD</keyword>
    <keyword evidence="6 12" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 12" id="KW-0534">Nitrate assimilation</keyword>
    <keyword evidence="8 19" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="17">
        <location>
            <begin position="6"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="Rubredoxin_C" evidence="18">
        <location>
            <begin position="322"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="Fer2_BFD" evidence="16">
        <location>
            <begin position="424"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="domain" description="NIR_SIR_ferr" evidence="15">
        <location>
            <begin position="561"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="domain" description="NIR_SIR" evidence="14">
        <location>
            <begin position="634"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="831"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="836"/>
            <end position="854"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR037149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF03460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF04324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF18267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EEZ39348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="854" mass="93763" checksum="6BBB368EDFA9F513" modified="2010-01-19" version="1">MSSKIKLVIIGNGMVGHRFIEDLVDKTDPQLFDITVFCEEPRVAYDRVHLSSYFSHHTAAELSLVKEGFYQQHGINVLIGERAININRENRVVYSSSGREVVYDKLILATGSYPWVPPIQGNENKDCFVYRTIEDLKAIEACAKKSKSGVVVGGGLLGLEAAGALKALGMETHVIEFAPVLMAEQLDLQGGLQLRNKIERMGVQVHTSKNTKEIVAQGQDARNTLNFADGTSLEVDFIVFSTGIRPQDKLARQAKLDIAPRGGIAINDVCQSSDPNIYAIGECASWNESFFGLVAPGYKMATVAVDHLLNRESVFEGADMSAKLKLLGVNVGSIGDANGRTPNCRSYVYLNEAEEVYKRLIVSEDGKKLLGAVLVGDTSDYGDLLQLTLNDIELPEHPDSLILPAHAGAEKPALGADALPDSAVICSCFDVTKGKIAQAVAEGNHTLADIKAVTGAGTGCGGCIPLVTSVLNAELAKSGIEVNHNLCEHFPYSRQEMFHLIRIESIKSFEEMLEKHGKGYGCETCKPAIGSILASCWGDHVLKPQNVPLQDTNDNFLGNLQKDGTYSVIPRMAGGEVTPLALAELANVARDYNLYTKITGAQRIGLFGAQKDDLPAIWQRLIDAGFETGQAYAKALRMAKTCVGSTWCRFGVQDSVGLGSLLENRYKGIRTPHKMKFGVSGCTRECAEAQGKDLGIIATDAGWNMYVCGNGGMKPRHADLLAADLDQTTLLQYIDRFMMFYIRTADKLQRTSVWLENMEGGIDYLREVIVNDSLGINKQLEADVARLVENYRCEWTETLQNPQQLKRFSHFINSDQRDDNVVFVPERDQHRPATYQEKHPQQQGDILHVSLENK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4G4</accession>
    <name>D0Z4G4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000420</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304318.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000420"/>
    <dbReference type="EnsemblBacteria" id="EEZ39402">
        <property type="protein sequence ID" value="EEZ39402"/>
        <property type="gene ID" value="VDA_000420"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2357">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1614527at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018912" evidence="1">
        <location>
            <begin position="26"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="263" mass="29921" checksum="8C58460D69CFF734" modified="2010-01-19" version="1">MDMKSILRTGVILLFMLGRTSVANADSSANNYVEPDFDLQQKYSLKSQKFFQKSLSGLYNVPSWQADSIQQPYSDFATLYQNAELAQHELSVMMHEIALASNAHPIIPTVKSEQRAKVKIAQELNGQVDRITDLSRATLIADDIPSLMQAFELLNKEARIVAVKNRFKNPAPSGYRDLKVLVELPKTQLIAEVQLHLDEIATIKNGEEHKIYEQIQKIERTAQAEARPFNDIEQTKIKKLRSISQQMYQDAWQQYLQPTTNVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4I5</accession>
    <name>D0Z4I5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Ribonucleotide reductase of class III (Anaerobic) large subunit</fullName>
            <ecNumber evidence="8">1.17.4.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_000443</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.17.4.2" evidence="8"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000443"/>
    <dbReference type="EnsemblBacteria" id="EEZ39423">
        <property type="protein sequence ID" value="EEZ39423"/>
        <property type="gene ID" value="VDA_000443"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1328">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008998">
        <property type="term" value="F:ribonucleoside-triphosphate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01675">
        <property type="entry name" value="RNR_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005144">
        <property type="entry name" value="ATP-cone_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019777">
        <property type="entry name" value="Form_AcTrfase_GR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001150">
        <property type="entry name" value="Gly_radical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012833">
        <property type="entry name" value="NrdD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03477">
        <property type="entry name" value="ATP-cone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13597">
        <property type="entry name" value="NRDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02487">
        <property type="entry name" value="NrdD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51161">
        <property type="entry name" value="ATP_CONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00850">
        <property type="entry name" value="GLY_RADICAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51149">
        <property type="entry name" value="GLY_RADICAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 5" id="KW-0556">Organic radical</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-cone" evidence="7">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="domain" description="Glycine radical" evidence="6">
        <location>
            <begin position="551"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="modified residue" description="Glycine radical" evidence="5">
        <location>
            <position position="649"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ39423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="674" mass="75789" checksum="2AEBC54474952B45" modified="2010-01-19" version="1">MDEAYATTVAEAVLAQFVNAEEVEIHAIQNAVETQLMTGPHKAVARAYIEYRHDRDISREKKSRLNNEIRGLIEQSNASLLNENANKDSKVIPTQRDLLAGIVAKHYATQHLLPRDIVKSHELGEIHYHDLDYSPFFPMFNCMLIDLNGMLTHGFKMGNAEIDTPKSISTATAVTAQIIAQVASHIYGGTTINRIDEVLAPYVQVSYDKHLAVANEWGIADPEAFAKARTEKECYDAFQSLEYEVNTLHTANGQTPFVTFGFGLGTTWASRLIQQSILRNRIAGLGKNHKTAVFPKLVFAIKDGLNHKQGDPNYDIKKLALECASKRMYPDILNYDKLVEVTGSFKTPMGCRSFLGPYENEQGELEHEGRNNLGVVSLNLPRIALEAKGDEARFFTLLDERLQLARRALDTRIERLEGVKARVAPILYMEGACGVRLNEDDNVSEIFKNGRASISLGYIGIHETVNALYGNETHVYDNEELRQKAVAIVQRLRDATDAWKEETGYGFSLYSTPSENLCSRFCALDTKEFGVVDGVTDKGYYTNSFHLDVEKQVNPYDKIDFEMPYPEIANGGFICYGEYPNIQHNIEALENVWDYSYSRVPYYGTNTPIDECYECGFTGEFSCTSKGFTCPKCGNHEPSKVSVTRRVCGYLGSPDARPFNFGKQEEVKRRVKHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4J9</accession>
    <name>D0Z4J9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000457</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304417.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000457"/>
    <dbReference type="EnsemblBacteria" id="EEZ39437">
        <property type="protein sequence ID" value="EEZ39437"/>
        <property type="gene ID" value="VDA_000457"/>
    </dbReference>
    <dbReference type="GeneID" id="57342624"/>
    <dbReference type="eggNOG" id="ENOG5032YRS">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021242">
        <property type="entry name" value="DUF2799"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10973">
        <property type="entry name" value="DUF2799"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="97"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="183" mass="21395" checksum="2E7166CF693832A9" modified="2010-01-19" version="1">MNENECRTANWYSLGYTDGMNGSDMANSLSNRSSACAEYNVAVNFNQYKSGYEQGVVAFCTESNGYYVASNGYNYRGICPKNLENQFLKGYQQGRKLNQLRQQASEIKDQLDQAEFDNNYQQSEIKRLKNKLIYDELTPRKRQNILQQLEQFQDNQSNIDHLQLEYAKAKQQIEDFKRSHSRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4K1</accession>
    <name>D0Z4K1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Multidrug resistance protein D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_000459</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000459"/>
    <dbReference type="EnsemblBacteria" id="EEZ39439">
        <property type="protein sequence ID" value="EEZ39439"/>
        <property type="gene ID" value="VDA_000459"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="46"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="71"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="95"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="130"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="206"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="240"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="270"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="296"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="331"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="357"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="1"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="380" mass="41263" checksum="EE617108DE565257" modified="2010-01-19" version="1">MKKLPPIWLLVCLMMLPQIAETIYSPILPSISQAFYVSVVDAGQTLSIYFIAFAVGVVFWGRMADILGRRSSMLLGLLCYALACIVAALTNSFSILLAARAMSAFGLAVGSVISQTILRDGYSGKDLAQTFNIMGLAISISPIIGLLAGTGLNILGGYRIVFIMLAVLALFIFIICYSRLNETQNELNVTDSFFSVAKKMVMDTKIWLSACLVAGFNLLIFVYYQQGAFFFESLGYSSQQFGYSGIVLALGTFGGGILNRRLLSMGYTSYFVIAIAGVISFFGGLCAYQLSNSLWLLAAVLVIVCSFGLAIPNILSVALNNYKTSIGSAGAIFGLFYYLMLGLGLNITAYVNHLSLSLLFTSAFIMIIAGLFFWLRNKQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4M2</accession>
    <name>D0Z4M2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_000480</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000480"/>
    <dbReference type="EnsemblBacteria" id="EEZ39460">
        <property type="protein sequence ID" value="EEZ39460"/>
        <property type="gene ID" value="VDA_000480"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1288">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018385">
        <property type="entry name" value="C4_dicarb_anaerob_car-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018387">
        <property type="entry name" value="YcgA/YfcC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43652:SF6">
        <property type="entry name" value="PTHR43652:SF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03606">
        <property type="entry name" value="DcuC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="23"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="110"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="152"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="237"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="287"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="318"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="357"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="485"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="510" mass="54699" checksum="9A7EA33793D78BE7" modified="2010-01-19" version="1">MQAVSNEKGSTGSKKKQWQIPDTFILIFLVGVFATVLTYLIPAGSFTQQEISYVVDGVEKTRSVVDPESFKVALNDQGEPVYNSVGFFASGGGIGLMNFVFEGLVSGSKWGSAIGVIMFMLVIGGAFGVVMRTGAIDNGILVLIDKTKGNDRFFIPTLFLLFSLGGAVFGMGEEAIAFAMIIAPLMLRLGYDGITTVMVTYIATQIGFATSWMNPFSVAIAQGIAGIPVLSGMEVRIPMWVGFTLLGMLYTMRYAARIKKNPELSYSRRTDASMREHNAEVQKSDWCLGYTLVIATVVFTTVWVVWGVVVHAWYIPEIASQFFTMGFIAGIIGVVFKLNGMRLNDIAASFKEGAGTMLAPALLVGCAKGVLLILGDGSATTPSVLNSILNSAGSVISGIPDVAAVWMMYLFQSIFNFFVTSGSGQAALTMPLLAPLGDIAGISRQVSVLAFQLGDGFTNVIVPTSAPLMATLGVCRIDWGDWARFCWRFMLLLFVTASIVVISAHLAGFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4T1</accession>
    <name>D0Z4T1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sex pilus assembly and synthesis protein TraW</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000164</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306485.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000164"/>
    <dbReference type="EnsemblBacteria" id="EEZ39148">
        <property type="protein sequence ID" value="EEZ39148"/>
        <property type="gene ID" value="VDA_000164"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031QWG">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1325284at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014114">
        <property type="entry name" value="TraW"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02743">
        <property type="entry name" value="TraW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003020086" evidence="1">
        <location>
            <begin position="24"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="256" mass="29188" checksum="910D71FFE70D326B" modified="2010-01-19" version="1">MRYGLRPLSLLLLCSLTFSPAYAKNLGTIAQTFPIAEIDMLDWIMARLRHFEATGELEKMQDEFTERVKQSAIRPTPVEGLTTTSTPTTYSIDPTLTLAEDIKDANGKVLFHKGLKINPFDSSTWPNAKGLPPLYLSKILVFLDGDDMRQLRFAKALQQQEQAKAHPLKFKWILVKGEPAKVQHFLKEKVYFDQLGNITKRFDIKHISTTAKQAGTRWEVKEFDVSQEDDTPIDAMVNAPSLQFINNKPIEEIERH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z561</accession>
    <name>D0Z561_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">TonB-dependent hemin ferrichrome receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">VDA_000111</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306880.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000111"/>
    <dbReference type="EnsemblBacteria" id="EEZ39095">
        <property type="protein sequence ID" value="EEZ39095"/>
        <property type="gene ID" value="VDA_000111"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4771">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="439303at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039426">
        <property type="entry name" value="BtuB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010949">
        <property type="entry name" value="TonB_Hb/transfer/lactofer_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30069">
        <property type="entry name" value="PTHR30069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01786">
        <property type="entry name" value="TonB-hemlactrns"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="4" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0675">Receptor</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0798">TonB box</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Plug" evidence="10">
        <location>
            <begin position="46"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="9">
        <location>
            <begin position="254"/>
            <end position="745"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ39095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="746" mass="85702" checksum="7FF7F8336BA51E78" modified="2010-01-19" version="1">MGRKNILPLLSLSFISCNLHAEDVSRFAEIVVSEAKEDALNKADITIGNEEINNELILDINDLVKNEPGVSVVQKANSGSSGFNIRGVDQDRVAILVDGIHQGETFENIIYTNYGYFDGSINEIELDSVKSVSINKGTDSLFTGSGSLGGAVSYTTKSASDLILGNKKYGLYNKTIYASNSSEVKTTSGVALKQDFGDLLVLYTYTTGHEQKTRDKGNDTYGRARSQVDPLNKNSHNILVKSNLLPNDSNKITLTYENYDVDKNVDERSWELFGSNYRKTHSIGQRQRYSIDWNYKNQGEYINEIDTKIYHQKISQVKDSDVYEFKNDKKEYNYNRRLDQSSVGFDQKISLTDNNIGSLSILNQLMYGYKTKKVSNDNVDTFYFSDRTSTISNSIIEPVTTEHYYVALTNEIDITPSQLVALGLRYDAYHHNVKRNGKSISEHLYSDTFVLPEDTSFSGLTYSALYDYQFNEQFNIKYKISTGFRAPNATELYFTYGDDFAANRFEPNQNLKEETGLTNELYLEYVADSWYVSFNPFYTKYNNFIDLKDEYRLVKNKYYDPIRYPKEFDDQKYFQYRNVDSAYIYGFDARFKLNVSELVDSYYPIWYQSRVSYSKGKGSDGDSLMTIQPWKWTNNFKFDIEDYNFSLYATYISKKDPQDTIRNGKPWKYTSDSALVMDFIVNYELNKNIKFNAGIFNFLNEKYKTWDSVRSIPTFGSTNMVDDDGLGLNRFTAPGVNWKAGVEIKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z571</accession>
    <name>D0Z571_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000121</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306908.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000004.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39105">
        <property type="protein sequence ID" value="EEZ39105"/>
        <property type="gene ID" value="VDA_000121"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031PT5">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="270" mass="31505" checksum="CAA5F0DB12FCC6C0" modified="2010-01-19" version="1">MSRAEQSQTQKAIAQRINELGSNKNEWRKAQFPYCTRRTLLAFAKFIDNPHAYENQLHDLLHCQTRVGGLQKRQRMNCVKVITVLMSKMDVENYQIGFAKSAEMETITHAWFMARYEQFWGETISLKRYYHTIHLLKMADYLVIDAVFVYDEEVPPVLDDNGQVKEEDAPRIYSKAAYKTITAKFMGIFGLENDEGVVKSKLQAVKNRLAKGLSNIWWVYAPYSYSYIWTKRQLAKVTKRDRVTGKERDRYPQGKVIEPDILGGNYLTEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z581</accession>
    <name>D0Z581_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">IncF plasmid conjugative transfer pilus assembly protein TraU</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000041</name>
        <name evidence="3" type="ORF">VDA_000131</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000005">
        <property type="protein sequence ID" value="EEZ39056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000041"/>
    <dbReference type="EnsemblBacteria" id="EEZ39056">
        <property type="protein sequence ID" value="EEZ39056"/>
        <property type="gene ID" value="VDA_000041"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39115">
        <property type="protein sequence ID" value="EEZ39115"/>
        <property type="gene ID" value="VDA_000131"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502Z7SA">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009649">
        <property type="entry name" value="TraU"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06834">
        <property type="entry name" value="TraU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5007650147" evidence="1">
        <location>
            <begin position="33"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="346" mass="38690" checksum="E150FB0718EA7437" modified="2010-01-19" version="1">MYTPYRELKLMTKPLLWVLGFSLLMASNAASASGPACRARFMNPITDICWECIFPITLGSVPLIPSRHPDTPNPSLPISFCPKPPPIFMQVGLNIGYWEPYAITDVTRVPFCMVNLGFSLGGGMSQQIGGQNSYKKPGDSSSGAFYQAHWYKYPLIYWLQILQSSACMAMDNFDVGYLTELDPFWDDDELSFILNPEAILFGNPIAQLACVAEAVKTSTSFFLPIDALFWCMGSQGSAYPLTGNTGYRDTPMQSAVLMAERLNYKLHRQGIVWESLGVDGAVCVQHPMPILPKSRYRYQLSNVIPNPFNCYPYGTTTAIWESGHDNPVTGDNFGFVQWRKRNCVFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z583</accession>
    <name>D0Z583_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">IncF plasmid conjugative transfer protein TraN</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000043</name>
        <name evidence="3" type="ORF">VDA_000133</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000005">
        <property type="protein sequence ID" value="EEZ39058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306939.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000005.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000043"/>
    <dbReference type="EnsemblBacteria" id="EEZ39058">
        <property type="protein sequence ID" value="EEZ39058"/>
        <property type="gene ID" value="VDA_000043"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39117">
        <property type="protein sequence ID" value="EEZ39117"/>
        <property type="gene ID" value="VDA_000133"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502Z9Z1">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="170450at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014121">
        <property type="entry name" value="TraN_Ftype"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06986">
        <property type="entry name" value="TraN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02750">
        <property type="entry name" value="TraN_Ftype"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5007650154" evidence="1">
        <location>
            <begin position="19"/>
            <end position="610"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="610" mass="67297" checksum="3B6C1CC3D7A1E885" modified="2010-01-19" version="1">MNQYLLLVTLLVSHIAAADVIGNRFHQEVPNAKASIQSSLSNPNFKGFNAEGYCKDQACINEMNNPSQSQYLNNDAALIAEGEKQLVTNPNAANITEGFNNRPKHTIDPNDPAYRNAKTYMDNSYNISHGISNKYVDCEGGDICKYVDTKRQCSEPTGQPTYCRSEAYVVSTGTKADRKTFTVNGTLGSYTLNKAETVTQIDTPTLTTDRVQNGVKCTNGNFTIAMTLWVNGSQVASFTGTRHQKTEGSGIFNSRCYVSYTVPARYTTLNPSRNLHTFRLEVKADNRTLAPKGHGYVIAHFTQKTVQMGWRDNCKGIPNQCSQTQEICVEGAGTRYINGVPVYLDCWKKKRTYQCQYPNTCTPLLGKAVTGAPLTCQIDNKGCKTQVLGVCVENSVNLTCEERQCEQTNLVCGETMFCLNGDCYFEEQKQNGNFSEAASALAALGEAAASLNADNLRIFTGKPAFCDKKPIGLSDCCADSGWGNDIGLTQCSAEEKGLASAKEKKLTIELGEYCAEKVLGVCIRKKKSYCQFDSKMTRIIQEQGKKQLGLGFGSKKEPDCQGFTPEQLQHVDFSKIDMSEFYGDLEANMELPNMQEIQDRINDKYGDLAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5C0</accession>
    <name>D0Z5C0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Guanine deaminase</fullName>
            <shortName evidence="4">Guanase</shortName>
            <ecNumber evidence="3 4">3.5.4.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Guanine aminohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_000027</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>guanine + H(+) + H2O = NH4(+) + xanthine</text>
            <dbReference type="Rhea" id="RHEA:14665"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16235"/>
            <dbReference type="ChEBI" id="CHEBI:17712"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="4">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 4">Purine metabolism; guanine degradation; xanthine from guanine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.3" evidence="3 4"/>
    <dbReference type="EMBL" id="ADBS01000005">
        <property type="protein sequence ID" value="EEZ39042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000027"/>
    <dbReference type="EnsemblBacteria" id="EEZ39042">
        <property type="protein sequence ID" value="EEZ39042"/>
        <property type="gene ID" value="VDA_000027"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0402">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00603">
        <property type="reaction ID" value="UER00660"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008892">
        <property type="term" value="F:guanine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006147">
        <property type="term" value="P:guanine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01303">
        <property type="entry name" value="GDEase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014311">
        <property type="entry name" value="Guanine_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11271:SF6">
        <property type="entry name" value="PTHR11271:SF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02967">
        <property type="entry name" value="guan_deamin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="5">
        <location>
            <begin position="68"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU366009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ39042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="434" mass="49313" checksum="51BCDC2A1561D9C1" modified="2010-01-19" version="1">MSNSIAIRASILHFINDPVKTDNISDSYQYLNDGLLVIENGCIKEMKNFDSIDKSKYNNFVDYSGKLICPGFIDTHIHYPQTQMISAYGEQLLEWLESYTFPTEQQFENKLHAKAISKFFVNELLKNGTTTALIFGTVHPQSVDALFEEALEKNMRIIAGKVMMDRNAPDYLLDTPETGYQESKNLINKWHNKGRLQYAITPRFAPTSSPEQLNAAGKLRLEYPEVYVQTHLSENKSEIEWVKSLYPDREGYFDVYEHYGLAGKKSIFAHSIHLTDKEWSDFERTDSVMSFCPTSNLFLGSGLFNIEKAEKHNIRIGLGTDIGAGTSFSQLESLNEAYKVMQLQGQKLSSFKGLYLATLGGAKALSIDDKVGNFIIGKEADFIVLDWASTELQKLRHKHSKNLEDKLFSLMMLGDERNIHATYLLGKIAYLNEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5F6</accession>
    <name>D0Z5F6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000063</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000006">
        <property type="protein sequence ID" value="EEZ39008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005307129.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000006.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39008">
        <property type="protein sequence ID" value="EEZ39008"/>
        <property type="gene ID" value="VDA_000063"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1833046at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="219" mass="25570" checksum="81AD265276153E29" modified="2010-01-19" version="1">MKLLNTADFFKKCRRPIYYKSRLNKLRNSETLILGSISEEIENQDNTINICAQAYIQKKTKGVYQFTGLWTVPTKPSRPMIWCSGDFRLEKSNLIFCNENSEVNLHNFFLICRWLNILKRVTENDYQSILPQDNYYHMNGLPYVFDGLELTKDYITKTPRVTRFKQISGNFVYYKTGNTAKISLEYNIHKILTPPLKAILDIGILTGSVNFDDDTPPWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVL2</accession>
    <name>D0YVL2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Na(+)/(H)+ antiporter NhaC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_001604</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40577">
        <property type="protein sequence ID" value="EEZ40577"/>
        <property type="gene ID" value="VDA_001604"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1757">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004770">
        <property type="entry name" value="Na/H_antiport_NhaC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018461">
        <property type="entry name" value="Na/H_Antiport_NhaC-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03553">
        <property type="entry name" value="Na_H_antiporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00931">
        <property type="entry name" value="antiport_nhaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="29"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="63"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="188"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="212"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="266"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="303"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="domain" description="Na_H_antiporter" evidence="7">
        <location>
            <begin position="114"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ40577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="435" mass="45902" checksum="8A8C59AFDFA3CC7C" modified="2010-01-19" version="1">MALGLKLGHDYKSLEKAATKGISNGLGAVLILLAVGALVGTWIAGGIVPTIIYYGLKAIHPSIFLLATMIICSLTALATGTSWGAAGTAGIAMMGIGQGLGIPPAMTAGAVLSGCYFGDKMSPLSDSVILASSMSNVEIVEHIKGMLPIALISYIITGVLFTLVGYHYSGNVDMSQVQSVIEAMDKQFVITPLSFVPVVIVLVLLAMRLPSFPVISLGSLLGIVWAIMVQDMDPLAAFNTAWAPFSIQSGVEFIDSILNRGGMESMLGSVAVIVFGLGFGGLLDKVGVLQTIAHLFEKRVNSAGSLSVSTIATAFLGNVFGSAMYVSLILTPKICAKNYDRLGYQRKNLSRNAEFGGTLTSGMVPWSDNGIYMASILGVATFSYAPFMWLSFVCIIVTIVSSYMGWFVDRCPPASAEQLAKDDEEEMLAVEKLTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-08-12" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVQ4</accession>
    <name>D0YVQ4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Sugar fermentation stimulation protein homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">sfsA</name>
        <name evidence="3" type="ORF">VDA_001219</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SfsA family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297662.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001219"/>
    <dbReference type="EnsemblBacteria" id="EEZ40197">
        <property type="protein sequence ID" value="EEZ40197"/>
        <property type="gene ID" value="VDA_001219"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1489">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1375946at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00095">
        <property type="entry name" value="SfsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005224">
        <property type="entry name" value="SfsA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040452">
        <property type="entry name" value="SfsA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041465">
        <property type="entry name" value="SfsA_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30545">
        <property type="entry name" value="PTHR30545"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03749">
        <property type="entry name" value="SfsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17746">
        <property type="entry name" value="SfsA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00230">
        <property type="entry name" value="sfsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ig-like" evidence="2">
        <location>
            <begin position="9"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="237" mass="26669" checksum="CCB2F1FC738BA970" modified="2010-01-19" version="1">MKFAKPLQPATLIKRYKRFLADVSLADGREITIHCANTGAMTGCAEPGSTVWYSTSDNPKRKYPNSWELTYTQQGNWICVNTAQANRLVEEAINHQIIPELAGYSTLRTEVKYGSENSRIDILLQDEAKADCYIEVKSVTLLAEHGQGLFPDAVTTRGQKHLRELMEMAQQGHRAVLFFAILHSGIENVAIAHHIDPNYYHLLKQAEQAGVEIICYQASIATDEMAINKRLQFHHSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-02-10" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVR0</accession>
    <name>D0YVR0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase OrfAB subunit B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002001</name>
        <name evidence="3" type="ORF">VDA_002038</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40969">
        <property type="protein sequence ID" value="EEZ40969"/>
        <property type="gene ID" value="VDA_002001"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41006">
        <property type="protein sequence ID" value="EEZ41006"/>
        <property type="gene ID" value="VDA_002038"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2801">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032196">
        <property type="term" value="P:transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038965">
        <property type="entry name" value="InsF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46889:SF1">
        <property type="entry name" value="PTHR46889:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="1">
        <location>
            <begin position="52"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="225" mass="26181" checksum="D26DCA47BD3FD60F" modified="2010-01-19" version="1">MVTTQGIPLSRYRASKQMKALNLVSCQSPKHRYRKANQEHIAIPNHLDRQFAVTSPNQVWVGDVTYVWAGNRWMYLAVVIDLFSRKPVGWAMSLSPDSRLTGKALMMAYESRHKPKGVMFHSDQGSHYTSSYYRQLLWRCQIKQSLSRRGNCWDNAPMERFFRSLKTEWVPNVGYCSFAEAKHEITRYIIGYYSQLRPHQYNGGLTPNESERLYWLTSNTVASIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVR8</accession>
    <name>D0YVR8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">M23/M37 peptidase/aminotransferase class III</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002009</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299164.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002009"/>
    <dbReference type="EnsemblBacteria" id="EEZ40977">
        <property type="protein sequence ID" value="EEZ40977"/>
        <property type="gene ID" value="VDA_002009"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0739">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1891666at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Peptidase_M23" evidence="1">
        <location>
            <begin position="86"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="221" mass="24890" checksum="79BA4021697510F5" modified="2010-01-19" version="1">MLNDLLKNHRFHPVVPKERQFGRALIVDLSPSSEIWQHVTEQHSFSDEMAQRAVAIEAQVVIGRYNEQRLIYQDTDNFAGQEHRTVHIGIDLGLPALTPIYAPYTAQVHSVANHNNDGDYGPTVILCHQLEGQKFYTLYGHLHWESVKALSVGQTIKTGEAFASIGTPEENGGWAPHLHLQVIKDMGKHHSDYPGVVDPKQLDFYLDNCPDPNLILGREDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-02-10" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVV1</accession>
    <name>D0YVV1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_002032</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002032"/>
    <dbReference type="EnsemblBacteria" id="EEZ41000">
        <property type="protein sequence ID" value="EEZ41000"/>
        <property type="gene ID" value="VDA_002032"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1380">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005538">
        <property type="entry name" value="LrgA/CidA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03788">
        <property type="entry name" value="LrgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="23"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="52" mass="5527" checksum="5F00E5929AEF312C" modified="2010-01-19" version="1">MALLFVPVGVGLMNYLDLISNNVAVIAASTFGSTFIVLVVLGLAVHHKEKDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVW4</accession>
    <name>D0YVW4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">D-3-phosphoglycerate dehydrogenase</fullName>
            <ecNumber evidence="6">1.1.1.399</ecNumber>
            <ecNumber evidence="7">1.1.1.95</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">2-oxoglutarate reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">VDA_001245</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>(2R)-3-phosphoglycerate + NAD(+) = 3-phosphooxypyruvate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:12641"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18110"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="EC" id="1.1.1.95"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(R)-2-hydroxyglutarate + NAD(+) = 2-oxoglutarate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:49612"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15801"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.399"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-serine biosynthesis; L-serine from 3-phospho-D-glycerate: step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 13">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.399" evidence="6"/>
    <dbReference type="EC" id="1.1.1.95" evidence="7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297718.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001245"/>
    <dbReference type="EnsemblBacteria" id="EEZ40223">
        <property type="protein sequence ID" value="EEZ40223"/>
        <property type="gene ID" value="VDA_001245"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0111">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1638924at2"/>
    <dbReference type="UniPathway" id="UPA00135">
        <property type="reaction ID" value="UER00196"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004617">
        <property type="term" value="F:phosphoglycerate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006564">
        <property type="term" value="P:L-serine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029753">
        <property type="entry name" value="D-isomer_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029752">
        <property type="entry name" value="D-isomer_DH_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01842">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00065">
        <property type="entry name" value="D_2_HYDROXYACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00670">
        <property type="entry name" value="D_2_HYDROXYACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00671">
        <property type="entry name" value="D_2_HYDROXYACID_DH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10" id="KW-0520">NAD</keyword>
    <keyword evidence="9 13 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0718">Serine biosynthesis</keyword>
    <feature type="domain" description="ACT" evidence="14">
        <location>
            <begin position="340"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00021582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEZ40223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="409" mass="44673" checksum="754237B5DF6FF4BC" modified="2010-01-19" version="1">MVKVSLNKDKIKILLLEGLHPSTVEVFKQAGYNNIEYHKGSLADDELREAIKDAHFVGIRSRTQLSDDVFAIANKLIAVGCFCIGTNQVDLKSATRRGIPVFNAPFSNTRSVAELVLGEILLLLRGIPEKNAKAHRGEWFKSADASFEARGKRLGIIGYGHIGTQLGILAENLGMRVYYYDIENKLSLGNATQVLSMTELLNKCDVISLHVPETPETKNMMGADEFARMKPGAIFINAARGTVVEIDALCSALESKHIAGAAIDVFPVEPKTNNDPFESPLMQYDNVLLTPHIGGSTQEAQENIGLEVAGKLVKYSDNGSTLSAVGFPEVSLPEQRECSRLLHIHQNRPGILNQITAIFADDGINIAAQFLQTGPEIGYVVIDVETEHAPQALQKLKAIEGTIRARILH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVX6</accession>
    <name>D0YVX6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNA polymerase sigma factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_001257</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297741.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001257"/>
    <dbReference type="EnsemblBacteria" id="EEZ40235">
        <property type="protein sequence ID" value="EEZ40235"/>
        <property type="gene ID" value="VDA_001257"/>
    </dbReference>
    <dbReference type="GeneID" id="57339855"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1914729at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000838">
        <property type="entry name" value="RNA_pol_sigma70_ECF_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014286">
        <property type="entry name" value="RNA_pol_sigma70_RpoE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02939">
        <property type="entry name" value="RpoE_Sigma70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01063">
        <property type="entry name" value="SIGMA70_ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="4">
        <location>
            <begin position="26"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="5">
        <location>
            <begin position="135"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="192" mass="21878" checksum="EF6360F561E4EEC6" modified="2010-01-19" version="1">MSEQQTDQVLIERVQRGDKQAFNLLVIKYQNKVCNLISRYVSNSGDVPDVAQEAFIKAYRALPTFRGDSAFYTWLYRIAVNTAKNYLVAQGRRPPASDIDADDAEYYETGSAMKEISNPENQMLSDELKRVVFSTIESLPEDLKMAITLRELDGLSYEEIAEVMGCPVGTVRSRIFRAREAVEKRIQPLLQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW05</accession>
    <name>D0YW05_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">30S ribosomal protein S16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rpsP</name>
        <name evidence="4" type="ORF">VDA_001310</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the bacterial ribosomal protein bS16 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297846.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001310"/>
    <dbReference type="EnsemblBacteria" id="EEZ40285">
        <property type="protein sequence ID" value="EEZ40285"/>
        <property type="gene ID" value="VDA_001310"/>
    </dbReference>
    <dbReference type="GeneID" id="57339798"/>
    <dbReference type="eggNOG" id="COG0228">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1937072at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00385">
        <property type="entry name" value="Ribosomal_S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000307">
        <property type="entry name" value="Ribosomal_S16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020592">
        <property type="entry name" value="Ribosomal_S16_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023803">
        <property type="entry name" value="Ribosomal_S16_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12919">
        <property type="entry name" value="PTHR12919"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00886">
        <property type="entry name" value="Ribosomal_S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54565">
        <property type="entry name" value="SSF54565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00002">
        <property type="entry name" value="S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00732">
        <property type="entry name" value="RIBOSOMAL_S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="83" mass="9163" checksum="5153145EB10EF430" modified="2010-01-19" version="1">MVTIRLARHGAKKRPFYHIVVADARVSREGRSIEKLGFFNPLAKGQEEALRLDLDRVNHWVGQGAAVSDRVAKLIKDAAKAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW26</accession>
    <name>D0YW26_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Type I restriction enzyme endonuclease subunit</fullName>
            <shortName evidence="10">R protein</shortName>
            <ecNumber evidence="10">3.1.21.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">VDA_001289</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Subunit R is required for both nuclease and ATPase activities, but not for modification.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endonucleolytic cleavage of DNA to give random double-stranded fragments with terminal 5'-phosphates, ATP is simultaneously hydrolyzed.</text>
            <dbReference type="EC" id="3.1.21.3"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">The type I restriction/modification system is composed of three polypeptides R, M and S.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the HsdR family.</text>
    </comment>
    <dbReference type="EC" id="3.1.21.3" evidence="10"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297803.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001289"/>
    <dbReference type="EnsemblBacteria" id="EEZ40264">
        <property type="protein sequence ID" value="EEZ40264"/>
        <property type="gene ID" value="VDA_001289"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0610">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="25184at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009035">
        <property type="term" value="F:type I site-specific deoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007409">
        <property type="entry name" value="Restrct_endonuc_type1_HsdR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004473">
        <property type="entry name" value="Restrct_endonuc_typeI_HsdR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040980">
        <property type="entry name" value="SWI2_SNF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021810">
        <property type="entry name" value="T1RH-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11867">
        <property type="entry name" value="DUF3387"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04313">
        <property type="entry name" value="HSDR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18766">
        <property type="entry name" value="SWI2_SNF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00348">
        <property type="entry name" value="hsdR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7 10 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0680">Restriction system</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="12">
        <location>
            <begin position="303"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="518"/>
            <end position="545"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU364115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ40264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="1074" mass="121845" checksum="8B1B30FD7136236C" modified="2010-01-19" version="1">MITEEQLEQQCINWFINQGYLYKNGYDIASDGDTPEREDYHQVILKQRLLARLEILNPDLPSDCLSVIVNTVSTPDTPVLIKSNRAFHKYLIEGVPVEYSVFEDGETKTKHTHARLMDFNEPDNNEFLVVNQFTITGKKGNRRPDIVVFINGLPISVIELKNPADEHADIWDAFNQLQTYKDEISDLFVFNEALIVSDGWTARVGSLTANKERFLPWKTVSTEEDRPLLEFQLETMVRGFFKQDLLLDYIRYFVLFETDNDKIIKKIAGYHQFHAVRAAVEATVRAANTSGNFLESAIPALKKIKQGSGKAGVVWHTQGSGKSISMVCYASKLLQQPAMNNPTIVVVTDRNDLDGQLYNTFGMANETLKQIPQQANDRDELRELLLNRQSGGIIFTTIQKFALLENEIEHPVLSERANIVVVSDEAHRSQYGNKSKLVSVKDADGNIIGSKYVFGYSKYMRDALPNASFIGFTGTPIAMDDKDTRGVFGEYVSVYDIQDAVDDGATVPIYYESRLAKLDINQAEIESLNDQIDDEISEEDETETREKIKSQWATLEKLVGAEPRLKQVAQDLVTHFTTRTETFPGKAMIVAMSREICVDLYNAIIAIKPEWHSDDPNQGAIKIVMTGSASDKEKMQPHIYDKKTKKLFEKRYKDTNDELKLVIVRDMWLTGFDAPCCHTMYIDKPMKGHNLMQAIARVNRVFKDKPGGLVVDYIGIASELKNALKTYTNSQGKGQPTVDTAEAFSVLMEKIDIVRGMFATPVDGAVFNYRPEFETNALRLLPGAVNHLSGLSYTNSNGKEERDGKRRFLDVMAAMTKAYSLCNTMDETQGYKNEIAFYSAIKTAFVKHSTVDKKRSDEQRNSVLKQILDNAIIAEGVDDIFSMVGLDKPNIGLLSDEFLEDVKNLKEKNLAVELLEKLLRDEVKARMKNDVVQEKKYSDRIMTTLQKYHNRSIETAQVIEELIKWAKEMAADAEMAAGLNLSPDEIAFYRALVLNEASVRELGDNNLRQLAIELTLQLRKSATVDWQKRESVRARMRNLVRRLLRRWKYPPDKADEAIKLVLEQAEVLADGWYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW34</accession>
    <name>D0YW34_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein RecA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_001297</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RecA family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001297"/>
    <dbReference type="EnsemblBacteria" id="EEZ40272">
        <property type="protein sequence ID" value="EEZ40272"/>
        <property type="gene ID" value="VDA_001297"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0468">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008094">
        <property type="term" value="F:ATP-dependent activity, acting on DNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013765">
        <property type="entry name" value="DNA_recomb/repair_RecA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020584">
        <property type="entry name" value="DNA_recomb/repair_RecA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023400">
        <property type="entry name" value="RecA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020587">
        <property type="entry name" value="RecA_monomer-monomer_interface"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45900">
        <property type="entry name" value="PTHR45900"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00154">
        <property type="entry name" value="RecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00142">
        <property type="entry name" value="RECA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54752">
        <property type="entry name" value="SSF54752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00321">
        <property type="entry name" value="RECA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50163">
        <property type="entry name" value="RECA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RECA_3" evidence="6">
        <location>
            <begin position="35"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="165"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="187" mass="20675" checksum="42FD36D5D29DD7B4" modified="2010-01-19" version="1">MQARMLSQAMRKLTGNLKQSNCMCIFINQIRMKIGVMFGNPETTTGGNALKFYASVRLDIRRTGSIKDGEEVVGNETRIKVVKNKIAAPFKQAETQILYGQGFNRVGKLIDLGVKQKLIEKAGAWYSYKGDKIGQGKANAGKYLTENPAIADEIEKQIRELLLTPPQEDTTEDASLDAIEAGEDKAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW37</accession>
    <name>D0YW37_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Aspartokinase</fullName>
            <ecNumber evidence="9">2.7.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">VDA_001300</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + L-aspartate = 4-phospho-L-aspartate + ADP</text>
            <dbReference type="Rhea" id="RHEA:23776"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57535"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 1/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 1/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 10">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 1/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 9">Belongs to the aspartokinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.4" evidence="9"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297825.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001300"/>
    <dbReference type="EnsemblBacteria" id="EEZ40275">
        <property type="protein sequence ID" value="EEZ40275"/>
        <property type="gene ID" value="VDA_001300"/>
    </dbReference>
    <dbReference type="GeneID" id="57339826"/>
    <dbReference type="eggNOG" id="COG0527">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1067792at2"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00015"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00461"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00462"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004072">
        <property type="term" value="F:aspartate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd04261">
        <property type="entry name" value="AAK_AKii-LysC-BS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041740">
        <property type="entry name" value="AKii-LysC-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005260">
        <property type="entry name" value="Asp_kin_monofn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001341">
        <property type="entry name" value="Asp_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018042">
        <property type="entry name" value="Aspartate_kinase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000726">
        <property type="entry name" value="Asp_kin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00657">
        <property type="entry name" value="asp_kinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00324">
        <property type="entry name" value="ASPARTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AA_kinase" evidence="11">
        <location>
            <begin position="9"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="13"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="179"/>
            <end position="180"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="215"/>
            <end position="216"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000726-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ40275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="398" mass="42927" checksum="EF2AF7C689D7D3E0" modified="2010-01-19" version="1">MTQKACKSLIVQKFGGTSVGSIERIHAVAERVIEAKEAGSQLVVVVSAMAGETNRLLDLAQKIDSVPTDRELDVLLSAGEQMSMALLAMTLNKLGHEAVSLTGWQAGIVTNQQFNNASIDSIDTTRIQSLLEQDKIVIVAGFQGITDEGDITTLGRGGSDTTAVALAGALNATECQIFTDVDGVYSCDPRVVPEACRLHTIDFPTMEAMAKQGAKVLHLPSVQFAWKNRVPLRVLSSFTKQGGTLVTGEECIHDISGIALQRDLLHVQVAHEDLAALEKQCYLLGIKVWTVISEAERAGVVIKQDAYAKLNLVFAEKIRNSVDVSSLTCVGNNVESVITKANQLLGEYNISVLATEPGIQCLLMLFEPDLVNKAANIIHEHYVLANVKQKDPQKVVVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW61</accession>
    <name>D0YW61_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Flap endonuclease Xni</fullName>
            <shortName evidence="4">FEN</shortName>
            <ecNumber evidence="4">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">xni</name>
        <name evidence="4" type="synonym">ygdG</name>
        <name evidence="6" type="ORF">VDA_001346</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
        <text evidence="4">Binds 1 K(+) per subunit. The potassium ion strongly increases the affinity for DNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="4">Binds 2 Mg(2+) per subunit. Only one magnesium ion has a direct interaction with the protein, the other interactions are indirect.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the Xni family.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297892.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001346"/>
    <dbReference type="EnsemblBacteria" id="EEZ40321">
        <property type="protein sequence ID" value="EEZ40321"/>
        <property type="gene ID" value="VDA_001346"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0258">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1220182at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017108">
        <property type="term" value="F:5'-flap endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030955">
        <property type="term" value="F:potassium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033567">
        <property type="term" value="P:DNA replication, Okazaki fragment processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09898">
        <property type="entry name" value="H3TH_53EXO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01192">
        <property type="entry name" value="Xni"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020046">
        <property type="entry name" value="5-3_exonucl_a-hlix_arch_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002421">
        <property type="entry name" value="5-3_exonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036279">
        <property type="entry name" value="5-3_exonuclease_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020045">
        <property type="entry name" value="DNA_polI_H3TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038969">
        <property type="entry name" value="FEN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008918">
        <property type="entry name" value="HhH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022895">
        <property type="entry name" value="Xni"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42646">
        <property type="entry name" value="PTHR42646"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01367">
        <property type="entry name" value="5_3_exonuc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02739">
        <property type="entry name" value="5_3_exonuc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00475">
        <property type="entry name" value="53EXOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00279">
        <property type="entry name" value="HhH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47807">
        <property type="entry name" value="SSF47807"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1 4" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="2 4" id="KW-0630">Potassium</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="53EXOc" evidence="5">
        <location>
            <begin position="3"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with DNA" evidence="4">
        <location>
            <begin position="189"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="258" mass="28589" checksum="E4D1C46638B32279" modified="2010-01-19" version="1">MAIHLVVIDALNLIRRVHAAQHGEPNVENTAQVCCQALTKIIAMSQPTHIVAVFDHNGEDRGWRAELLPKYKEGRKPMPEELAQGMDKIQDAFMAMGIDSLLSSGDEADDLVATLAIKVASHNEQVTIISTDKGYCQLLQPTLRIRDYFQERWLDSPFIEQEYGVKPEQLPDYWGLAGISSSKIPGIPGIGPKAAVELLSQYGDLESVLSADDLAEKWQKKILGNEDLARACKQVASLKTDLELGFNLQDIRYTSSTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW82</accession>
    <name>D0YW82_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001341</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40316">
        <property type="protein sequence ID" value="EEZ40316"/>
        <property type="gene ID" value="VDA_001341"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031NGE">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2182016at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="123" mass="13213" checksum="208B7B784C3C9A3A" modified="2010-01-19" version="1">MALLLSGSTLVGCNAIENAAGKMVLGDEFVKASEGLDRCDLSGLNYLQRTTDDNNKMMSSAALIALGAHYAADGDMNKVNLIAKRLEKHSDSQSFNQIKKDILDSGKKEAQTRIDNGFSANCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW85</accession>
    <name>D0YW85_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Chaperone protein skp</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001367</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homotrimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the skp family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297931.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001367"/>
    <dbReference type="EnsemblBacteria" id="EEZ40342">
        <property type="protein sequence ID" value="EEZ40342"/>
        <property type="gene ID" value="VDA_001367"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2825">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1854604at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.910.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005632">
        <property type="entry name" value="Chaperone_Skp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024930">
        <property type="entry name" value="Skp_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35089">
        <property type="entry name" value="PTHR35089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03938">
        <property type="entry name" value="OmpH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002094">
        <property type="entry name" value="OMP26_Skp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00935">
        <property type="entry name" value="OmpH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111384">
        <property type="entry name" value="SSF111384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0574">Periplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019840" description="Chaperone protein skp" evidence="3">
        <location>
            <begin position="24"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR002094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="169" mass="18868" checksum="9442198F330E0554" modified="2010-01-19" version="1">MKQWVKAAGLSLVILSSSMYANAAEAAQKIGYVATGQAMAQLAKRYNVQDKLRKEFSGRVNELRSLEKKMKAKIDKLKRDGAVMSDSDRTKLQRELASLESSYKLKAQALAEDQRRRGQEEEQKLVMKIRTAIDSVAKKEGYNLVLDANAVLFASKKDDLSQKVISAVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWB2</accession>
    <name>D0YWB2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Type 4 fimbrial assembly ATPase PilB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001190</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GSP E family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297602.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001190"/>
    <dbReference type="EnsemblBacteria" id="EEZ40168">
        <property type="protein sequence ID" value="EEZ40168"/>
        <property type="gene ID" value="VDA_001190"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2804">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="749544at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009297">
        <property type="term" value="P:pilus assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013374">
        <property type="entry name" value="ATPase_typ4_pilus-assembl_PilB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001482">
        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037257">
        <property type="entry name" value="T2SS_E_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007831">
        <property type="entry name" value="T2SS_GspE_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00437">
        <property type="entry name" value="T2SSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05157">
        <property type="entry name" value="T2SSE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160246">
        <property type="entry name" value="SSF160246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02538">
        <property type="entry name" value="type_IV_pilB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00662">
        <property type="entry name" value="T2SP_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T2SP_E" evidence="4">
        <location>
            <begin position="384"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="563" mass="62494" checksum="E4C8614A29619E69" modified="2010-01-19" version="1">MHTTLASILHQADLISSVQQQQVEDSVSMEGITVPSALIHLGIFSDRELAQHLSHIFGLTLVSVHDYDFEACCKAVYQRDLVLRHRALPLAQNVDTLFLGVSDPCNIDGQDEFRFATGRNIEPLLLENKQLESAIRRIYGRELGETTNMASRDVSDDDLNNLVDIGDDELDQTTDLGQENEPVTRYINQVLLDAVRKKASDIHFEPYETSYRIRFRCDGILHQHATPPAHLSRRLSTRLKVMSRLNIAERRQPQDGRIKLKLTANLAVDLRVSTLPTLWGEKVVLRILDSSSANLDIDILGYNQQQKAAYLNALQQPQGMILMTGPTGSGKTVSLYTGLSILNTEERNISTAEDPVEINLPGINQVHINNQAGLGFAEALRSFLRQDPDVVMVGEIRDLETASIAVKAAQTGHLVLSTLHTNSAAETITRLTNMGIEDFNLASSLTLIIAQRLGRRLCPHCKQVDEIDGFMQDKLRIPTGTTLYKANPAGCDDCNKGYLGRVGIYEVMPFSRRLAQALVDGATTLELENIAVEEGMLTLQQSGIEKLCLGITSLKELQRVLHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWB7</accession>
    <name>D0YWB7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Proline--tRNA ligase</fullName>
            <ecNumber evidence="9">6.1.1.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Prolyl-tRNA synthetase</fullName>
            <shortName evidence="9">ProRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">proS</name>
        <name evidence="11" type="ORF">VDA_001380</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + L-proline + tRNA(Pro) = AMP + diphosphate + L-prolyl-tRNA(Pro)</text>
            <dbReference type="Rhea" id="RHEA:14305"/>
            <dbReference type="Rhea" id="RHEA-COMP:9700"/>
            <dbReference type="Rhea" id="RHEA-COMP:9702"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78532"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.15"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2 9">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="9">Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.15" evidence="9"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297970.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001380"/>
    <dbReference type="EnsemblBacteria" id="EEZ40355">
        <property type="protein sequence ID" value="EEZ40355"/>
        <property type="gene ID" value="VDA_001380"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0442">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="665824at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004827">
        <property type="term" value="F:proline-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006433">
        <property type="term" value="P:prolyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00861">
        <property type="entry name" value="ProRS_anticodon_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00779">
        <property type="entry name" value="ProRS_core_prok"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01569">
        <property type="entry name" value="Pro_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002316">
        <property type="entry name" value="Pro-tRNA-ligase_IIa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004500">
        <property type="entry name" value="Pro-tRNA-synth_IIa_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023717">
        <property type="entry name" value="Pro-tRNA-Synthase_IIa_type1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044140">
        <property type="entry name" value="ProRS_anticodon_short"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033730">
        <property type="entry name" value="ProRS_core_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036754">
        <property type="entry name" value="YbaK/aa-tRNA-synt-asso_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007214">
        <property type="entry name" value="YbaK/aa-tRNA-synth-assoc-dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04073">
        <property type="entry name" value="tRNA_edit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001535">
        <property type="entry name" value="ProRS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01046">
        <property type="entry name" value="TRNASYNTHPRO"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55826">
        <property type="entry name" value="SSF55826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00409">
        <property type="entry name" value="proS_fam_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 11" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="10">
        <location>
            <begin position="38"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ40355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="572" mass="63298" checksum="485D9EDBC87F35E1" modified="2010-01-19" version="1">MRTSNYLLSTLKETPNDAEIISHQLMLRAGMIRKLASGLYTWLPTGLRVLRKVENIVRQEIDNAGAVETLMPVVQPFELWEETGRSEKMGPELLRFTDRHARPFVLSPTAEEVITSLVRNEVSSYKQLPLNLYQIQTKFRDERRPRFGVMRAREFCMMDAYSFDIDKEGLQKSYDAMHDAYCKAFDRMGLEYRPVWADSGAIGGNGSQEFHVLAESGEDLIAFSTESDYAANIEKAEALAPAHDRAAPTVELSVIDTPNAKTIDELVEQHGIAIEKTTKTLFVKASDEIDAPIVALLVRGDHELNEIKAENLDWVASPLEMATEEEIRQFVNAGPGSLGPVGLELPFIVDRTVAVMSDFAAGANIDGKHHVGINWDRDVALGRVEDLRNVVEGDPSPCGQGTLMLKRGIEVGHIFQLGTTYSEKMNCGVLDSNGKNVILEMGCYGIGVSRVVASAIEQNNDENGIIWPDAIAPFQVSIVPMNMAKSEEVKEAAEKLYADLTAAGIDVLFDDRKERPGVMFADHELIGIPHTIVIGNRSLENGEMEYKNRRTGTKENVAVTDIVAFVTSKLAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWC2</accession>
    <name>D0YWC2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">D,D-heptose 1,7-bisphosphate phosphatase</fullName>
            <ecNumber evidence="5">3.1.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_001385</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the gmhB family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.-" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297976.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001385"/>
    <dbReference type="EnsemblBacteria" id="EEZ40360">
        <property type="protein sequence ID" value="EEZ40360"/>
        <property type="gene ID" value="VDA_001385"/>
    </dbReference>
    <dbReference type="GeneID" id="57339703"/>
    <dbReference type="eggNOG" id="COG0241">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1472357at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006549">
        <property type="entry name" value="HAD-SF_hydro_IIIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004446">
        <property type="entry name" value="Heptose_bisP_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006543">
        <property type="entry name" value="Histidinol-phos"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42891">
        <property type="entry name" value="PTHR42891"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004682">
        <property type="entry name" value="GmhB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00213">
        <property type="entry name" value="GmhB_yaeD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01662">
        <property type="entry name" value="HAD-SF-IIIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01656">
        <property type="entry name" value="Histidinol-ppas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="9"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="17"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="51"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="107"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="6">
        <location>
            <position position="9"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="11"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="11"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="134"/>
        </location>
    </feature>
    <feature type="site" description="Stabilizes the phosphoryl group" evidence="8">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <feature type="site" description="Contributes to substrate recognition" evidence="8">
        <location>
            <position position="107"/>
        </location>
    </feature>
    <feature type="site" description="Stabilizes the phosphoryl group" evidence="8">
        <location>
            <position position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00031828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR004682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR004682-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR004682-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR004682-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR004682-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ40360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="184" mass="20448" checksum="A547778D21600542" modified="2010-01-19" version="1">MAKPAVFIDRDGVINVDHGYVHTTDDFEYVEGVFAACKKLKEMGYLLVLVTNQSGIARGMFTEDEFLSLTEWMDWNFVDNGVEFDGIYYCPHHPEGQGDYRQECDCRKPKPGMLISARDYLKIDMAQSVMIGDKADDMTAAKAAEVGTKILVRTGKPVTEVGEQLADVVLDSVADVPAWLASQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWF7</accession>
    <name>D0YWF7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">4-hydroxy-tetrahydrodipicolinate synthase</fullName>
            <shortName evidence="9">HTPA synthase</shortName>
            <ecNumber evidence="4 9">4.3.3.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">dapA</name>
        <name evidence="11" type="ORF">VDA_001416</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 9">Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>L-aspartate 4-semialdehyde + pyruvate = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H(+) + H2O</text>
            <dbReference type="Rhea" id="RHEA:34171"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:67139"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="4.3.3.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 9">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 3/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homotetramer; dimer of dimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9 10">Belongs to the DapA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.</text>
    </comment>
    <dbReference type="EC" id="4.3.3.7" evidence="4 9"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298025.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001416"/>
    <dbReference type="EnsemblBacteria" id="EEZ40390">
        <property type="protein sequence ID" value="EEZ40390"/>
        <property type="gene ID" value="VDA_001416"/>
    </dbReference>
    <dbReference type="GeneID" id="57339658"/>
    <dbReference type="eggNOG" id="COG0329">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1438588at2"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00017"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008840">
        <property type="term" value="F:4-hydroxy-tetrahydrodipicolinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019877">
        <property type="term" value="P:diaminopimelate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00950">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00418">
        <property type="entry name" value="DapA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005263">
        <property type="entry name" value="DapA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002220">
        <property type="entry name" value="DapA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020625">
        <property type="entry name" value="Schiff_base-form_aldolases_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020624">
        <property type="entry name" value="Schiff_base-form_aldolases_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128">
        <property type="entry name" value="PTHR12128"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00701">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001365">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00146">
        <property type="entry name" value="DHPICSNTHASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01130">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00674">
        <property type="entry name" value="dapA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00665">
        <property type="entry name" value="DHDPS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00666">
        <property type="entry name" value="DHDPS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0220">Diaminopimelate biosynthesis</keyword>
    <keyword evidence="9 10 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 9" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0704">Schiff base</keyword>
    <feature type="active site" description="Proton donor/acceptor" evidence="9">
        <location>
            <position position="133"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="9">
        <location>
            <position position="161"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </ligand>
    </feature>
    <feature type="site" description="Part of a proton relay during catalysis" evidence="9">
        <location>
            <position position="44"/>
        </location>
    </feature>
    <feature type="site" description="Part of a proton relay during catalysis" evidence="9">
        <location>
            <position position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR001365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ40390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="292" mass="31110" checksum="F9140254F5FC6A65" modified="2010-01-19" version="1">MFSGSIVALITPLDAAGEVDYDNLRSLVEYHIAAGTTAIVAVGTTGESATLTVDEHIKVVLKTIEFANGRIPVIAGSGANATHEAVTMVKLFAGTGVAACLSVTPYYNKPTQEGLYQHYKAIAEATEIPQILYNVPGRTGVDLLPETVARLAKLDNIIGIKDATADLARVKKTRELCGPDFIQLSGDDATGIEFMAEGGHGVISVTTNIAAKEMAAMYQFALDGDFEQAQHINQQLMPLHEKLFVEANPIPVKWAALQLGMINNGTLRLPLTELSATAQPVVKQALKDANLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWL0</accession>
    <name>D0YWL0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">WbcZ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001501</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001501"/>
    <dbReference type="EnsemblBacteria" id="EEZ40475">
        <property type="protein sequence ID" value="EEZ40475"/>
        <property type="gene ID" value="VDA_001501"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1215">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="865276at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="16"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="268" mass="31021" checksum="BE6B3FBA503245C6" modified="2010-01-19" version="1">MNNISVLMSLYKGEKAHFFFEALKSIEVQTIQPAEIIVVHDGPLTKELYDTLDIWRDKLPIKEVVLAENQGLGVALNKGLDACSYEIVARVDTDDINLDERFAVQYQFMMENPDVELCSAHIAEFDNDISVISGLRKVPLSDQIEKVIYRRNPINHMAVMFRKSAVIKAGGYQHMPYMEDYYLWVRMHAKGMNIANIDDVLVYARVGNGMLERRQGYKYYRSELRFMKQLLKLPIKDKSKIAMIFLARAHMRLLPTKILGNIYKLVRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWQ1</accession>
    <name>D0YWQ1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Release factor glutamine methyltransferase</fullName>
            <shortName evidence="5">RF MTase</shortName>
            <ecNumber evidence="5">2.1.1.297</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">N5-glutamine methyltransferase PrmC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Protein-(glutamine-N5) MTase PrmC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Protein-glutamine N-methyltransferase PrmC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">prmC</name>
        <name evidence="8" type="ORF">VDA_001447</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-methionine = H(+) + N(5)-methyl-L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42896"/>
            <dbReference type="Rhea" id="RHEA-COMP:10271"/>
            <dbReference type="Rhea" id="RHEA-COMP:10272"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30011"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61891"/>
            <dbReference type="EC" id="2.1.1.297"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.297" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298076.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001447"/>
    <dbReference type="EnsemblBacteria" id="EEZ40421">
        <property type="protein sequence ID" value="EEZ40421"/>
        <property type="gene ID" value="VDA_001447"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2890">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1816476at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102559">
        <property type="term" value="F:protein-(glutamine-N5) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036009">
        <property type="term" value="F:protein-glutamine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018364">
        <property type="term" value="P:peptidyl-glutamine methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02126">
        <property type="entry name" value="RF_methyltr_PrmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004556">
        <property type="entry name" value="HemK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040758">
        <property type="entry name" value="PrmC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019874">
        <property type="entry name" value="Release_fac_Glu-N5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13847">
        <property type="entry name" value="Methyltransf_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17827">
        <property type="entry name" value="PrmC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00536">
        <property type="entry name" value="hemK_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03534">
        <property type="entry name" value="RF_mod_PrmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PrmC_N" evidence="7">
        <location>
            <begin position="8"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="Methyltranfer_dom" evidence="6">
        <location>
            <begin position="114"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="5">
        <location>
            <begin position="121"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="188"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ40421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="282" mass="30935" checksum="BB9A94E6B18ADCF2" modified="2010-01-19" version="1">MSRSIEVLLKQTAQELQTAGCPSPQLDAAVLLCHALDKPRSYLLTWPEKELDESQFSLFSHCVSRRLAGEPVAYIIGVREFWSLPLKVAPSTLIPRPDTERLVELALDKIPAQPCQVLDLGTGTGAIALAIASERPDITVTGIDLRQEAAQLATENGATLGFNNVQFLAGSWYSPLAEIQQFAVIVSNPPYIDEQDPHLDQGDVRFEPKSALVAADNGLADIKIIAEQGRQHLQTNGWLLLEHGFEQGLAVREILTKLGYQAVVTEQDYAGLDRVTLGCWQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWY4</accession>
    <name>D0YWY4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">UPF0283 membrane protein VDA_001817</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_001817</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the UPF0283 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298763.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001817"/>
    <dbReference type="EnsemblBacteria" id="EEZ40785">
        <property type="protein sequence ID" value="EEZ40785"/>
        <property type="gene ID" value="VDA_001817"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3768">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1529001at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01085">
        <property type="entry name" value="UPF0283"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021147">
        <property type="entry name" value="DUF697"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006507">
        <property type="entry name" value="UPF0283"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39342">
        <property type="entry name" value="PTHR39342"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05128">
        <property type="entry name" value="DUF697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01620">
        <property type="entry name" value="hyp_HI0043"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="210"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="342" mass="38086" checksum="C5DA18E2B4467984" modified="2010-01-19" version="1">MSEQYKSKILFDESSPDIQTEQEKELTSQISFDEDKKFLPKQADNTEIEQELDQILASKPKRRGGFFKGLLLAGAAMVGWQSVDYVVTAYQSADWLSLGWSVLVAGIATMGITALGRELLNLRRLKHRQTERDQAQELLNADGIGNGKAFCTKLAKQSQISTENTGYDRWIHSLAATHNDREVMALYDKMVVSQQDKMARQLVARYSSEAAVMVALSPLAIADMLLVAWRNFRLIEQVSNVYGVELGYWSRIRLVKLVLANMAFAGASEIATDIGTEVLSMDLAGRMSTRVAQGVGIGLLTGRLGLKAMTLMRPLPWLPGEQPKLSEIRHDLIAQLTKKKDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX37</accession>
    <name>D0YX37_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001893</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298886.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001893"/>
    <dbReference type="EnsemblBacteria" id="EEZ40861">
        <property type="protein sequence ID" value="EEZ40861"/>
        <property type="gene ID" value="VDA_001893"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0209">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="993263at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="228" mass="25679" checksum="18443AEDD5703F04" modified="2010-01-19" version="1">MVRKIEQNIVGFKVKNHVEGTPIQEETAPLEQMHESMPRPEKLVGATYKLKTPEHISEHSLFITINDVVLNEGTEHEIRRPFEVFINSKSLEHYQWIVALTRIMSAVFRKGGDCTFLVEELRSVFDPRGGYWNQGKYVPSLIAEIGNIIEMHLIEIGMINKPELDQHQQAFIDAKKAELSGNSVSNEQEHADSNFPPSATLCYKCHAKAVVVKDGCQTCLNCGDSKCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-02-10" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXC1</accession>
    <name>D0YXC1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative proton/glutamate symporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_001661</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298467.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001661"/>
    <dbReference type="EnsemblBacteria" id="EEZ40634">
        <property type="protein sequence ID" value="EEZ40634"/>
        <property type="gene ID" value="VDA_001661"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1301">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="781228at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001991">
        <property type="entry name" value="Na-dicarboxylate_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036458">
        <property type="entry name" value="Na:dicarbo_symporter_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00375">
        <property type="entry name" value="SDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118215">
        <property type="entry name" value="SSF118215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="155"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="193"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="225"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="303"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="336"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="438" mass="46188" checksum="A517D8CECAAF172F" modified="2010-01-19" version="1">MKAEKKKMSLTGRVILGMVLGILTGFIIRSLFADVAFIHDYIVNGLFDVGGKIFIASLKMLVVPLVFVSLVCGTSSLKDITTLGRLGGKTLAFYIATTAIAITLALTMGTLFKPGAGADLTAATSFSAKEAPSLGDVIIGMFPTNPISSMAQGNTLQIIVFAILFGIAISAAGKPGERLAAVFSDLNEVIMKLVALLMNIAPFGVFFLMAKLFTGLGLDAIFNLLGYFLVLTATLLIHGLVTYSVMLKSFTGLSPKTFFKKMEDAIMFAFSTASSNATIPVTMETATKRMGVNNKIASFTVPLGATINMDGTAIMQGVATAFIAQAFNIDLTMSDYLAVIMTATLASIGTAGVPGVGLIMLAMVLNQVGLPVEGIALIMGVDRLLDMIRTAVNITGDTVVTCIVAKTEGELDLDRFHDPLAGEEDETVSFHGREQQAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXG1</accession>
    <name>D0YXG1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001696</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298531.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001696"/>
    <dbReference type="EnsemblBacteria" id="EEZ40667">
        <property type="protein sequence ID" value="EEZ40667"/>
        <property type="gene ID" value="VDA_001696"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1652">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2063919at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007055">
        <property type="entry name" value="BON_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04972">
        <property type="entry name" value="BON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="SSF54106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50914">
        <property type="entry name" value="BON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BON" evidence="1">
        <location>
            <begin position="17"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="2">
        <location>
            <begin position="90"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="142" mass="15406" checksum="2DB5835818E89677" modified="2010-01-19" version="1">MGLLDFARDIGKKLFSNEDEAPAKITQHIEENNPGVNDLQVNVENGVATLSGSADSAAAREKAILMAGNAQGIESVVDNISAPEEMANVTYYIVEDGDSLWIIAEKTLGNGAKYEQIFEENKEVIQNPDLIFPGQKLRITQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXL3</accession>
    <name>D0YXL3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphorelay protein LuxU</fullName>
            <ecNumber evidence="3">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">VDA_001728</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298588.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001728"/>
    <dbReference type="EnsemblBacteria" id="EEZ40698">
        <property type="protein sequence ID" value="EEZ40698"/>
        <property type="gene ID" value="VDA_001728"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004721">
        <property type="term" value="F:phosphoprotein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00088">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036641">
        <property type="entry name" value="HPT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008207">
        <property type="entry name" value="Sig_transdc_His_kin_Hpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01627">
        <property type="entry name" value="Hpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00062">
        <property type="entry name" value="PBPb"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47226">
        <property type="entry name" value="SSF47226"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50894">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="21" id="KW-0418">Kinase</keyword>
    <keyword evidence="15" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 14" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 16" id="KW-0732">Signal</keyword>
    <keyword evidence="21" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="12" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019207" description="Phosphorelay protein LuxU" evidence="16">
        <location>
            <begin position="22"/>
            <end position="1249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="513"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="19">
        <location>
            <begin position="625"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="17">
        <location>
            <begin position="691"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="18">
        <location>
            <begin position="1003"/>
            <end position="1119"/>
        </location>
    </feature>
    <feature type="domain" description="HPt" evidence="20">
        <location>
            <begin position="1150"/>
            <end position="1248"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="14">
        <location>
            <position position="1052"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphohistidine" evidence="13">
        <location>
            <position position="1189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="EEZ40698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="1249" mass="142035" checksum="5327DD6E44E793E9" modified="2010-01-19" version="1">MRKIYTLLLLYLFSASSFAYAPIDQKENILTSEEISWLNNQDEIRYGILNYDWPPYYIHKKDGSVEGIYIDYANDINNFLDIKRKSKFIPYSSIKELEHALVNNEIDAVVGLSPTLRRNKIMWFTHSLYQESLGIIIKNSIIGFDADAIADLKWGCVTSSSYCDVLITAGGQHLQQTKNLTEAITLFKQGEIDAILSDYVVLSQQEDDINNARIISADWLRASTHNIAIQKNNIYLRDIFNKVIEFTPQGSESRIKDEIKSQTKNIKAENKLTKVILGNPEIKQTAFSYTLPGNLVPFSALNTNKGFTHDLLSLISMETGLRFNYLKTNDSVDYKKLLTDNKIDFLPIANINDIDEEQFLITEPYTTLKYAVITTKNRPELSKLSDLGKFKIGMIKSEKYFINTNNTQGDIKSYPNYKNLIDELLQGKVDYVVVVYSSFMAHLKQRYGINDFRVAYIGNDLVFPISMAINKDNQTLAQILNLALKSVPAEDISQLRKKYQPSIILKGFDESKVILWTSISIFIAVAVIALFLFWSNQLKKEVKRREKAEKKAVQQLDLLNEIIESIPSMLLMQDTNNQRVFWNNNYKETFSQFWNHNNMQPSWEEYNKSTLENATVLKTGIDINNTSKNNLRQTILPDGTTVDLIYTKKLIKDRDNNKLGVMTVLTDVSDLIQAQEKAERAMQARTHFLATMSHELRTPIASMIGLIDILETKNPSQEQLNYIKNLKSSTNHLLYLVNDILDFSQIEAGQLKLDYQPCRWLTEIGLSLINFAQEAQHKGVKFNLFWQPTKLTTLTIDSIRVNQVINNLLSNAIKFTEAGSISVYIELTQHSLLVKVIDTGIGIHEDNIKRLFSPFEQAEKTISRTYGGTGLGLSICKQLVEMMNGKIELHSQLNEGTTVIFKVPYSQGDIEPIEQNDPIYLEKAHPTIEQWLKIWDINYRIATNQIDFPLLQIDATYSAQPSYNISTDPLFPGQLRELIERINNNDDTISTAHKAQYPHLLGRILVAEDHQINQIILNNMLTQFGIQADFANDGEEALNLWQQNHYDLLLTDCHMPNMDGYELASQIRQGSVNSHVPIIGITADCSSQSTTRGSVIGMNHVMFKPYGIDELYAQLTQYLSVSLNHTAPLEQIKSPENISVKPQWLSTFAEQEPITDIAQVFVFSMKDDVEALTLAINQGNSEQIRRIAHRVKGALSLVKLEHLANMAANLQASAEAETDFSLITQQAIALQKEITAEIETTSNWLSTYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXN7</accession>
    <name>D0YXN7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AMMECR1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001736</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298600.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001736"/>
    <dbReference type="EnsemblBacteria" id="EEZ40704">
        <property type="protein sequence ID" value="EEZ40704"/>
        <property type="gene ID" value="VDA_001736"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2078">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1812209at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.700.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023473">
        <property type="entry name" value="AMMECR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036071">
        <property type="entry name" value="AMMECR1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002733">
        <property type="entry name" value="AMMECR1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027485">
        <property type="entry name" value="AMMECR1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027623">
        <property type="entry name" value="AmmeMemoSam_A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13016">
        <property type="entry name" value="PTHR13016"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01871">
        <property type="entry name" value="AMMECR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143447">
        <property type="entry name" value="SSF143447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04335">
        <property type="entry name" value="AmmeMemoSam_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51112">
        <property type="entry name" value="AMMECR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMMECR1" evidence="1">
        <location>
            <begin position="12"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="202" mass="23063" checksum="39A8B684675CB2C1" modified="2010-01-19" version="1">MPLTPYNHYNKGELTQLLDIAREAIRGHLFDDPSGIPELDLYTKKMRLPTACFVTLEVAGQLQGSIGTTRPTLPLVLEVHNKAISSAYEDRRFMPLAEEQLDTLTIEVSVLSQLERLKCEDEASLIDYLSQHQIGVQLTFDHKQAIMLPQAWCHDTTPSKFIQMLKLKAGLAMNFWHPDIVIEIFTVDSLKEKYNSIRGQYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXR9</accession>
    <name>D0YXR9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Aminopeptidase N</fullName>
            <ecNumber evidence="4">3.4.11.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">VDA_002082</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of an N-terminal amino acid, Xaa-|-Yaa- from a peptide, amide or arylamide. Xaa is preferably Ala, but may be most amino acids including Pro (slow action). When a terminal hydrophobic residue is followed by a prolyl residue, the two may be released as an intact Xaa-Pro dipeptide.</text>
            <dbReference type="EC" id="3.4.11.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M1 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.2" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299377.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002082"/>
    <dbReference type="MEROPS" id="M01.005"/>
    <dbReference type="EnsemblBacteria" id="EEZ41050">
        <property type="protein sequence ID" value="EEZ41050"/>
        <property type="gene ID" value="VDA_002082"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0308">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="771837at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045357">
        <property type="entry name" value="Aminopeptidase_N-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038438">
        <property type="entry name" value="PepN_Ig-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001930">
        <property type="entry name" value="Peptidase_M1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012779">
        <property type="entry name" value="Peptidase_M1_pepN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024601">
        <property type="entry name" value="Peptidase_M1_pepN_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037144">
        <property type="entry name" value="Peptidase_M1_pepN_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035414">
        <property type="entry name" value="Peptidase_M1_pepN_Ig-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46322">
        <property type="entry name" value="PTHR46322"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11940">
        <property type="entry name" value="DUF3458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17432">
        <property type="entry name" value="DUF3458_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17900">
        <property type="entry name" value="Peptidase_M1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00756">
        <property type="entry name" value="ALADIPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="SSF63737"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02414">
        <property type="entry name" value="pepN_proteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="8 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase_M1_N" evidence="14">
        <location>
            <begin position="37"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M1" evidence="11">
        <location>
            <begin position="230"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3458" evidence="12">
        <location>
            <begin position="449"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3458_C" evidence="13">
        <location>
            <begin position="553"/>
            <end position="873"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00015611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF11940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF17432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF17900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEZ41050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="874" mass="99594" checksum="EE42AB926C44BD16" modified="2010-01-19" version="1">MSDITNTNQPTAKYRADYTAPDYTISDIDLTFDLYDTQTKVLAVSQVKRLTDASSAVLALDGDGLKLIRVSVDGQPWTAYQETESQLILSNLPESFELTIETEINPEANTLLEGLYKSGGAYCTQCEAEGFRRITFYLDRPDVLARFTTKVIADNEYPFLLSNGNRIAEGQLDNGRHWVQWQDPFPKPSYLFALVAGDFDVLKDHFITMSGRKVELEIFVDKGNLDRATYAMTSLQNAMKWDEERFGLEYDLDIYMVVAVDFFNMGAMENKGLNVFNSKFVLANPKTATDTDYQGIESVIGHEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSSDLGSRPVNRIANVRIIRGPQFAEDRGPMSHPIRPEKVIEMNNFYTLTVYEKGSEVIRMMHTLLGEEKFQAGMKLYFERHDGTAATCDDFVQAMEDASKIDLSRFRRWYSQSGTPVVTVTTEYDQDKARYAVTIKQETAATPNQEEKLPLHIPFDIELYNQDGEPYELRCNGESIHHILDVTEAEQTFVFEGITTQPVISMLREFSAPVVLQYDYSDDELIFLMTHARNEFARWDAGQMLLAKYIRHNVTRVQQGNNVELSEAVVDAFRDVLLSTELDPAFIAEMLTLPSENEIAGWYQCVDVDSIHHVVGELTKILANAMSDEFSAIYHSLTQKQYSLDHQAMAQRTLRNQCLSYLALTEQGNALVDAQYQAADNMTDTMAAMNAANNAQLACREAQMTDFSEKWTHDGLVMDKWFMLQGKNPADNALQVVRETMNHPAFSLKNPNRTRSLVVSFTANNPVHFHAKDGSGYLFLTEILTHLNTSNPQVAARLIEPFLKYRQYDAERQQLMRAELEKLANLDNLAKDLFEKIHKALEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXT3</accession>
    <name>D0YXT3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Hypothetical oxidoreductase short chain dehydrogenase/reductase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002096</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002096"/>
    <dbReference type="EnsemblBacteria" id="EEZ41064">
        <property type="protein sequence ID" value="EEZ41064"/>
        <property type="gene ID" value="VDA_002096"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="263" mass="28691" checksum="233DA20E00732BA7" modified="2010-01-19" version="1">MSDKFWSLFSSIGKKFSHDRDIMTGKVYLVTGGASGIGRGICLYLAKKNATVIALDINEDVGFELVSQEPRIRFRQADVTSESDIQAVITDIEKNFGRLDGLVNNAAISDPYNAPLSELAMADWQRVLNVNLTAPLYISQQCLPLLKQSHGSIIHLSSTRASQSEPNTEAYSATKGAIVALTHSMAMSLGPDIRVNCISPGWINANHSELREIDHQQHPVGRVGVVDDIAAMVSFLLSEESGFITGQNFTIDGGMTKKMIYSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY21</accession>
    <name>D0YY21_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">50S ribosomal protein L25</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rplY</name>
        <name evidence="4" type="ORF">VDA_002184</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the bacterial ribosomal protein bL25 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299606.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002184"/>
    <dbReference type="EnsemblBacteria" id="EEZ41152">
        <property type="protein sequence ID" value="EEZ41152"/>
        <property type="gene ID" value="VDA_002184"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1825">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1864712at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008097">
        <property type="term" value="F:5S rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00495">
        <property type="entry name" value="Ribosomal_L25_TL5_CTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.240.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01336">
        <property type="entry name" value="Ribosomal_L25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020056">
        <property type="entry name" value="Rbsml_L25/Gln-tRNA_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029751">
        <property type="entry name" value="Ribosomal_L25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011035">
        <property type="entry name" value="Ribosomal_L25/Gln-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020055">
        <property type="entry name" value="Ribosomal_L25_short"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01386">
        <property type="entry name" value="Ribosomal_L25p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50715">
        <property type="entry name" value="SSF50715"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="92" mass="10484" checksum="DC1F3E0E7E61B6E4" modified="2010-01-19" version="1">MKFEAVVRTDLGKGASRRLRHANQFPAIVYGGEEAPVAIVLDHDSVINQMDKPAFYEVITLVIDGKEVQVKPQDIQRHPYKPKVNHMDFNRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY44</accession>
    <name>D0YY44_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Cytochrome c-type protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">VDA_002207</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="8">Binds 5 heme groups per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the TorC/TorY family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002207"/>
    <dbReference type="EnsemblBacteria" id="EEZ41175">
        <property type="protein sequence ID" value="EEZ41175"/>
        <property type="gene ID" value="VDA_002207"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3005">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009276">
        <property type="term" value="C:Gram-negative-bacterium-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3820.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009154">
        <property type="entry name" value="Membr-bd_4haem_cyt_TorC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036280">
        <property type="entry name" value="Multihaem_cyt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005126">
        <property type="entry name" value="NapC/NirT_cyt_c_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038266">
        <property type="entry name" value="NapC/NirT_cytc_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03264">
        <property type="entry name" value="Cytochrom_NNT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000014">
        <property type="entry name" value="4_hem_cytch_TorC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48695">
        <property type="entry name" value="SSF48695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="7 8" id="KW-0349">Heme</keyword>
    <keyword evidence="7 9" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Cytochrom_NNT" evidence="10">
        <location>
            <begin position="2"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="binding site" description="covalent" evidence="8">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="8">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="8">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="8">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="8">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="8">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>3</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="8">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>4</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="8">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>4</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>4</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="8">
        <location>
            <position position="317"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>5</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="8">
        <location>
            <position position="320"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>5</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="321"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>5</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR000014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000014-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000014-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ41175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="372" mass="41356" checksum="CB175DDE0A69DA9C" modified="2010-01-19" version="1">MLALVLVGIGITLAGIFAVHKGFEHASQTEFCTSCHTMQQNYEEYKQSVHFKNASGVRAECVDCHQPKDLPGAIQRKLGAWKDVYNHYITKKIDTPEKFEEHRLELAQMVWNRMSEQKSKTCKSCHDYSAMDHAKQSPEAAKAMTEAAAKDMNCIECHKGIAHELPNMAGGFQKSFQGLQAEATAQGAKADKLYSLGEKDLYATDDAKGKVEGKLLPASEVTVLERKGDMLKVEVNGWLEKAGKGRVMTEYMGKRVFKATIRGEVKANEKVIKEETDPATDIVWQNVAVQAWITKADMIDNIQPIWNYAEEMYGSTCNACHAAPDPGHFTANGWIASLKAMSSYYRLTKTEERTLLKYLQNHGKDTGGAGAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY54</accession>
    <name>D0YY54_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002217</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41185">
        <property type="protein sequence ID" value="EEZ41185"/>
        <property type="gene ID" value="VDA_002217"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5032Z72">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1969744at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019878" evidence="1">
        <location>
            <begin position="32"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="189" mass="21058" checksum="EF7768B7DA7D548C" modified="2010-01-19" version="1">MTNMTKQPGIKSKLVKLAAPIALACAFSVSAAPAATNSAPARPQVSAQVQQAAQRVGQIQQELATIRNKTLKANPKLVKDIKAYETAFDNKAKALGYHPDQELKRLREIQTKARDQKTTDAQRKDLAKEFASIQQKLIKQRQTIMSDPAISKMEQQLEKNTITAMKKQDPKTDKLLKELDSLMAKFKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY71</accession>
    <name>D0YY71_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HTH lysR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002234</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299705.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002234"/>
    <dbReference type="EnsemblBacteria" id="EEZ41202">
        <property type="protein sequence ID" value="EEZ41202"/>
        <property type="gene ID" value="VDA_002234"/>
    </dbReference>
    <dbReference type="GeneID" id="57341612"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="750230at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="2"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="300" mass="34007" checksum="94824514471E7105" modified="2010-01-19" version="1">MFSYHDLLVIDVVARRGSFSAAAEELHKVPSAISYTVRSIEERLAVDLFVRMHRQVKLTPAGEYFVEEARKLIKQMEQIKFRTQQVANGWSESVSVALDTVVRERQANMLVRDFYREFPDVELHLTMEVFNGVWDALADGRADIAIGATAAVPVGGNFDYRDMGMLTWTFVLAPDHPLADAKEPLTSDELAKYPAICLEDTSRTLPKRVTWLMDNQRRIMVPNWHSALQCLKAGLGISVVPTHMAIPLLEKGELVERELAVKPAVSPCCLAWNKERLSPAVTWILDYLGDSDKLHRDWMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY83</accession>
    <name>D0YY83_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Sodium/glutamate symporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">gltS</name>
        <name evidence="2" type="ORF">VDA_002246</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the sodium-dependent transport of glutamate.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299727.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002246"/>
    <dbReference type="EnsemblBacteria" id="EEZ41214">
        <property type="protein sequence ID" value="EEZ41214"/>
        <property type="gene ID" value="VDA_002246"/>
    </dbReference>
    <dbReference type="GeneID" id="57341597"/>
    <dbReference type="eggNOG" id="COG0786">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1284248at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015501">
        <property type="term" value="F:glutamate:sodium symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015813">
        <property type="term" value="P:L-glutamate transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02062">
        <property type="entry name" value="GltS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004445">
        <property type="entry name" value="GltS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36178">
        <property type="entry name" value="PTHR36178"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03616">
        <property type="entry name" value="Glt_symporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00210">
        <property type="entry name" value="gltS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="1" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="1" id="KW-0406">Ion transport</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0915">Sodium</keyword>
    <keyword evidence="1" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="1" id="KW-0769">Symport</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="162"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="227"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="257"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="287"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="313"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="346"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="380"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="410" mass="43953" checksum="252EAE01E5A73F7C" modified="2010-01-19" version="1">MNTTIHINELESLLIAIIVLFLGSFINSKIKVLQKYNIPEPIVGGLIVAILITLLHLEGVDVVFKLSMKDTLMQMFFATVGLAASYKLLLQGGSRVLLFLGLATVFIIIQDAVGVSLAKVLGLDPLLGLIVGSITLSGGHGTGAAWSQTFAQQYGLTNTLELSMAAATFGLVMGGIIGGPIAQRLIKKHNLTSSFGEGKNHHDQHPELVTYSENEEDRITSKTTIEVLFILLVCVAGASHVKTFIDGFGISSLNIPEFVYSLFIGVFITNICESTKAYKINNETVDALGTISLSLFLAMALMSLHLWELLDLALPMLAILAVQTVVLGLFTYFVTFRVMGSNYDAAVIVGGHCGFGMGATPTAVMNMGSLVSRYGPSPQAFMVVPIVGAFFIDIANLIVLQGYLMFIAPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYB4</accession>
    <name>D0YYB4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transmembrane component MtsC of energizing module of methionine-regulated ECF transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_002277</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CbiQ family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299774.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002277"/>
    <dbReference type="EnsemblBacteria" id="EEZ41245">
        <property type="protein sequence ID" value="EEZ41245"/>
        <property type="gene ID" value="VDA_002277"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0619">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1479665at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003339">
        <property type="entry name" value="ABC/ECF_trnsptr_transmembrane"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02361">
        <property type="entry name" value="CbiQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="28"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="118"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="251"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="280" mass="31884" checksum="6167B374B002583D" modified="2010-01-19" version="1">MKSNKFKFGISYINTGSILHQLNGITKFILFMSWVTMVLITFDLRIICGLIVLGLALLKMSKVPFSVYKPLLIGTLVVLMMNALFMFLIAPNQGTDYMGSKTVLVPLFGHYDITAETLFYLLTVTLKYFSMFPIALVFVFTTHPTEFSASLNKLGVPYRVSYAVSLTLRYLPEVMKDFTNIMHAQQARGVDISKNAPVMVRIKNVAKILGPLIFSSLDRADVISNAMTLRGFGRNKRRTWYSLKPMKTNDYIVIAIITLVLVLGFIKRYHDTTLFWYPFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYD5</accession>
    <name>D0YYD5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 13">Biotin synthase</fullName>
            <ecNumber evidence="3 13">2.8.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">bioB</name>
        <name evidence="16" type="ORF">VDA_002298</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 13">
            <text>(4R,5S)-dethiobiotin + [sulfur carrier]-SH + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = 2 5'-deoxyadenosine + [sulfur carrier]-H + biotin + 2 L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:22060"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57586"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="ChEBI" id="CHEBI:149473"/>
            <dbReference type="EC" id="2.8.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13 14">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="13 14">Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13 14">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="13 14">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 13">Cofactor biosynthesis; biotin biosynthesis; biotin from 7,8-diaminononanoate: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the radical SAM superfamily. Biotin synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.6" evidence="3 13"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299815.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002298"/>
    <dbReference type="EnsemblBacteria" id="EEZ41266">
        <property type="protein sequence ID" value="EEZ41266"/>
        <property type="gene ID" value="VDA_002298"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0502">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="940969at2"/>
    <dbReference type="UniPathway" id="UPA00078">
        <property type="reaction ID" value="UER00162"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004076">
        <property type="term" value="F:biotin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009102">
        <property type="term" value="P:biotin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01694">
        <property type="entry name" value="BioB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010722">
        <property type="entry name" value="BATS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002684">
        <property type="entry name" value="Biotin_synth/BioAB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024177">
        <property type="entry name" value="Biotin_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22976">
        <property type="entry name" value="PTHR22976"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06968">
        <property type="entry name" value="BATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001619">
        <property type="entry name" value="Biotin_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00272">
        <property type="entry name" value="biotin_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00876">
        <property type="entry name" value="BATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00433">
        <property type="entry name" value="bioB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13 14" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="4 13 14" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="9 13" id="KW-0093">Biotin biosynthesis</keyword>
    <keyword evidence="10 13 14" id="KW-0408">Iron</keyword>
    <keyword evidence="11 13 14" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8 13 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 13 14" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 13 16" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Radical SAM core" evidence="15">
        <location>
            <begin position="38"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="260"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR001619-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EEZ41266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="350" mass="39446" checksum="AAE375AB9A26A02F" modified="2010-01-19" version="1">MEARHNWNVEEVQQLLDQPFMDLLFQAQQVHRQYHDPNQVQVSTLLSIKTGACPEDCKYCPQSAHYRTDVERERLMEVEQVLTAAQKAKESGATRFCMGAAWKNPKSRDMPYLLDMIKGVKSLGLETCMTLGMLTPEQANILADAGLDYYNHNLDTSPEYYGNIITTRTYQDRLDTLDHVRQAGMKICSGGIIGMGESHRDRAGLLVELANLPVHPESVPINMLVKVKGTPLEQEEDVEPFDFIRMIAVARIMMPQSAVRLSAGREQMNEQMQAMCFMAGANSIFYGCKLLTTPNPKEDKDMVLFEKLGINRQQQAAKPDQVQAQELLTKVALQVASRPAKDDLFYDASI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYD8</accession>
    <name>D0YYD8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">L-lactate permease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_002301</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Transports L-lactate across the membrane. Can also transport D-lactate and glycolate.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell inner membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the lactate permease family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002301"/>
    <dbReference type="EnsemblBacteria" id="EEZ41269">
        <property type="protein sequence ID" value="EEZ41269"/>
        <property type="gene ID" value="VDA_002301"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1620">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015129">
        <property type="term" value="F:lactate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003804">
        <property type="entry name" value="Lactate_perm"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30003">
        <property type="entry name" value="PTHR30003"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02652">
        <property type="entry name" value="Lactate_perm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00795">
        <property type="entry name" value="lctP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="40"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="63"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="91"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="145"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="181"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="224"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="252"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="278"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="318"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="388"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="428"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="466"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="515"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="544"/>
            <end position="565"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU365092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="566" mass="60881" checksum="1006A782BA836B4D" modified="2010-01-19" version="1">MPRILFPRRSLISNTYSLRVINNKTTNTLFSGNYYPEWDMLNLIISVVPIILLIWMMTKKNSYPSHIALPVTALLVGLIQLFYFEANTTLLAANIVTGVLSAITPISIIAGAILLNRTLAVSGAEDVIRQWLEGVSKNQVAQLMIIGWAFAFMIEGASGFGTPAAIAAPILVGLGFNPLKVAMLALVMNSVPVSFGAVGTPTWFGFGTLGLSDAELLNTGRLTAAVHFVAGFIIPVLALKFVVSWQQIRRNFIFIQLSALSCTVPYLLLAQWNYEFPALIGGAIGMTISIFIAKAGIGLSKETETNTENTVEKLPFKTVLTAMAPTLILIAILIVTRIQQLGIKGLLNDATPLFNLHLGFADLSISQALIIKLSDVFGTNASWAYKTLYVPALIPFFVVVLISIPLLKMSSAQSKQVVTETLSRIKMPFIALVGALIMVKFMMIGGDHSPIMTTGKAFSELTGKNWQFFASYLGALGAFFSGSATVSNLTFGGIQQTIAQTVGLPQDMILAMQSVGGAMGNMVCINNIIAVSTILGIANKEGFIIKRTVIPMVIYGIIAAVVSLFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYF7</accession>
    <name>D0YYF7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sensor histidine protein kinase UhpB glucose-6-phosphate specific</fullName>
            <ecNumber evidence="8">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_002320</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299859.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002320"/>
    <dbReference type="EnsemblBacteria" id="EEZ41288">
        <property type="protein sequence ID" value="EEZ41288"/>
        <property type="gene ID" value="VDA_002320"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3851">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007895">
        <property type="entry name" value="MASE1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05231">
        <property type="entry name" value="MASE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="56"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="80"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="112"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="142"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="186"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="213"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="316"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ41288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="510" mass="57473" checksum="9150F3CAE8F22BE8" modified="2010-01-19" version="1">MRNYIVTSICSFFLVLCTWFCLWIISSYFIMEAELAILFFPFAFRLGMVLHTPKKYWFVLYGAEWFLTISLAILLAQPQWISVLISSIASLPIVWYADKFYLSKEASSATQWYQLSILGAVIGITSLLNMLIVSHQGVSSGLVLLVSITGGLMIVPSCYLIWNYLFKQSWSPLTANVVAYPVALRARHVIVYAVVFLLSILAQLLLPEELKRFAPFCLAIPIILLAFRYGWQGALLGTLLNSIALIAVRSGVSNIEITDLMLSLSAQTLTGILLGIGVQRQRELNLYLRHELERNQSLSRQLVKAEESVRKNIARELHDEIGQNITAIRMQAGILKRVETSPMGEKCASMIEGLSLNVYDTTKGLLTQLRPKTLDDLGLKAAIEQLIFELRSHQMSVELNWFPEQSETITFNDETNVTLYRICQEALNNIAKYAQATKVVLNFHFDEQIELSISDNGIGFKQEDTLKGFGLRGMRERVQALGGEFSITSIPKYSEQIKSGTQLHVRLPQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYM5</accession>
    <name>D0YYM5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ribosomal large subunit pseudouridine synthase B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002388</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300008.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002388"/>
    <dbReference type="EnsemblBacteria" id="EEZ41356">
        <property type="protein sequence ID" value="EEZ41356"/>
        <property type="gene ID" value="VDA_002388"/>
    </dbReference>
    <dbReference type="GeneID" id="57341411"/>
    <dbReference type="eggNOG" id="COG1187">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1037615at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120159">
        <property type="term" value="F:rRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000748">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB/E/F"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00093">
        <property type="entry name" value="TIGR00093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S4" evidence="2">
        <location>
            <begin position="3"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="275"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="275"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="385" mass="43943" checksum="25D26E7F013E07B6" modified="2010-01-19" version="1">MSEKLQKVLARAGQGSRREIELMIQNGRVSVDGDVAKLGDRLEDMTASVRIDGRRIELVASTDEVCRVLAYNKPEGELCTRHDPEGRRTVFDRLPRLNNGRWVSVGRLDANTSGMLLFTTDGELANRLMHPSHSVQREYMVRVFGEISEDMVRNLVRGVELEDGMARFEDVVYAGGEGMNHTFYVVITEGRNREVRRLWASQGVTVSRLKRVRYGDIYLSKELPRGGWMELELNDVNYLRELVGLQPETETELTVEGQKRKRNVRQIRRAVRRFEERADNTNSRRRNDRRSTTRNSDVEKAGNDKPRRPSTRSSDVDKAGNQKPRRPSTRNSGADKAENNKPRRQPRQNDADNKGGNKARKPAGNGANRRNPLASKPTNKPRTRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYS1</accession>
    <name>D0YYS1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Tol-Pal system protein TolB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">tolB</name>
        <name evidence="9" type="ORF">VDA_002434</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the TolB family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300082.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002434"/>
    <dbReference type="EnsemblBacteria" id="EEZ41402">
        <property type="protein sequence ID" value="EEZ41402"/>
        <property type="gene ID" value="VDA_002434"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0823">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="821953at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017038">
        <property type="term" value="P:protein import"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00671">
        <property type="entry name" value="TolB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="PD40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014167">
        <property type="entry name" value="Tol-Pal_TolB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007195">
        <property type="entry name" value="TolB_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04052">
        <property type="entry name" value="TolB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02800">
        <property type="entry name" value="propeller_TolB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 7" id="KW-0132">Cell division</keyword>
    <keyword evidence="5 7" id="KW-0574">Periplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5009009105" description="Tol-Pal system protein TolB" evidence="7">
        <location>
            <begin position="22"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="TolB_N" evidence="8">
        <location>
            <begin position="23"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="449" mass="49841" checksum="D5B0E9416F659053" modified="2010-01-19" version="1" precursor="true">MKRWIMGLCLMLLTVSQFARAELELVITDGVDSARPIAVVPFKWEGQGKLPTDISAVVASDLQRSGKFSPVPVAKMPQQPSDESQINYNAWTQMGVDALVMGTVSQDANGNYVVQYQLIDLVKGQLQSKQTTADANGQVVTEKNYILVNNRATVKPNRLRQYAHRISDVVYQKLTGERGAFLTRIAYVAMEEKSKFPYQLRVADYDGYNERTVLKSQQPIMSPAWSPDGSKLAYVSFENNKAQIYIMNIYKGTRELVSDYPRHNGSPRFSPDGSKLALVLSKSGSLQIYIKDLNTKQLTQVTRGRANNTEPFWDPTGNSLIFTSDRGGKPQIYRVNLADGQTQRLTWQGSQNLGGQLTPDGRYLVMVNRSDTGYNIAKQDLKTGAVQVLTKTFLDESPSIAPNGSMIIYSSSIGNSNELSLVSIDGRFKARLPSASDRVRSPAWGPFLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYS5</accession>
    <name>D0YYS5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Cytochrome d ubiquinol oxidase subunit I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">VDA_002438</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cell inner membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the cytochrome ubiquinol oxidase subunit 1 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002438"/>
    <dbReference type="EnsemblBacteria" id="EEZ41406">
        <property type="protein sequence ID" value="EEZ41406"/>
        <property type="gene ID" value="VDA_002438"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1271">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070069">
        <property type="term" value="C:cytochrome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019646">
        <property type="term" value="P:aerobic electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002585">
        <property type="entry name" value="Cyt-d_ubiquinol_oxidase_su_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30365">
        <property type="entry name" value="PTHR30365"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01654">
        <property type="entry name" value="Cyt_bd_oxida_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006446">
        <property type="entry name" value="Cyt_quinol_oxidase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 12" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 12" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5 12" id="KW-0349">Heme</keyword>
    <keyword evidence="10 12" id="KW-0408">Iron</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="50"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="87"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="143"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="179"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="347"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="380"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="430"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR006446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ41406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="486" mass="54088" checksum="25492085E9A0094D" modified="2010-01-19" version="1">MTGKQIYKDMTKFWGKLFAINFALGVATGLSMEFQFGTNWAYYSHYVGDIFGAPLAIEALMAFFLESTLVGMFFFGWDRLSKRQHLAVTWLVALGSNFSALWILVANGWMQNPVGADFNFETMRMEMVSFADVVLNPVAQVKFVHTVASGYTTGAMFILGISAYYLLKGRDIAFARRSFAIAAAFGLAAIISTIILGDESGYELGDVQKTKLAAIEAEWHTEPAPAAFTAIAIPNQEKMENDFQIKVPYLLGIIATRSLDEQVTGIVDLKKEHEIRIRNGMIAYGLLDKLRAGDKSPENIAAFDKVKKDLGYGLLLKPYAPNVVDATEADIQKATDDSIPTVWPLFWSFRVMVGAGMLMLGIIGMAFIQSCRHKITEKKWVLKAALYGIPLPWIAVEAGWFVAEYGRQPWAVGEVLPVHMAASNLQPYELWLSLLGIIALYTIFLIAELYLMIKYARLGPSSLKTGRYHFEKIDSQQNAVSRQVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZA2</accession>
    <name>D0YZA2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Flagellar basal-body rod protein FlgF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_002615</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="4">The basal body constitutes a major portion of the flagellar organelle and consists of five rings (E,L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Bacterial flagellum basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the flagella basal body rod proteins family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300494.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002615"/>
    <dbReference type="EnsemblBacteria" id="EEZ41583">
        <property type="protein sequence ID" value="EEZ41583"/>
        <property type="gene ID" value="VDA_002615"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4787">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="947161at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030694">
        <property type="term" value="C:bacterial-type flagellum basal body, rod"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001444">
        <property type="entry name" value="Flag_bb_rod_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020013">
        <property type="entry name" value="Flagellar_FlgE/F/G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010930">
        <property type="entry name" value="Flg_bb/hook_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037925">
        <property type="entry name" value="FlgE/F/G-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012836">
        <property type="entry name" value="FlgF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00460">
        <property type="entry name" value="Flg_bb_rod"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06429">
        <property type="entry name" value="Flg_bbr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117143">
        <property type="entry name" value="SSF117143"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03506">
        <property type="entry name" value="FlgEFG_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02490">
        <property type="entry name" value="flgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="7" id="KW-0966">Cell projection</keyword>
    <keyword evidence="7" id="KW-0969">Cilium</keyword>
    <keyword evidence="7" id="KW-0282">Flagellum</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flg_bb_rod" evidence="5">
        <location>
            <begin position="5"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="Flg_bbr_C" evidence="6">
        <location>
            <begin position="173"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF06429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="249" mass="27074" checksum="6FC2B77582DB5BF0" modified="2010-01-19" version="1">MDRALYLAMNGAQQDMLGLQVRANNLANVSTTGFRADLEQARSMQAYGEGVPDRVFTMAERPGYNFTQGSVITTGRDLDVAVEGDGWLAVQDASGNEAYTRAGHLKIDQTGMLQNSNGQLVLGQNDSPIFIPLPISKIEIGRDGTISVLPQGAPPEAMAQIDRIKLVKTDNHQLFKDADGLFKFKGGQEPQQADASIRLLNGTLEGSNVNAVGEMTALIDLQRHFEMQVKLMKTAEEMDKSSSSLMRIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZC7</accession>
    <name>D0YZC7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytochrome c-type protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">VDA_002640</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
        <text evidence="9">Binds 4 heme groups per subunit.</text>
    </comment>
    <comment type="PTM">
        <text evidence="8">Binds 4 heme groups per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the NapC/NirT/NrfH family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300574.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002640"/>
    <dbReference type="EnsemblBacteria" id="EEZ41608">
        <property type="protein sequence ID" value="EEZ41608"/>
        <property type="gene ID" value="VDA_002640"/>
    </dbReference>
    <dbReference type="GeneID" id="57341099"/>
    <dbReference type="eggNOG" id="COG3005">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1683334at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019333">
        <property type="term" value="P:denitrification pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3820.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036280">
        <property type="entry name" value="Multihaem_cyt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024717">
        <property type="entry name" value="NapC/NirT/NrfH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005126">
        <property type="entry name" value="NapC/NirT_cyt_c_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038266">
        <property type="entry name" value="NapC/NirT_cytc_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03264">
        <property type="entry name" value="Cytochrom_NNT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000013">
        <property type="entry name" value="4_hem_cytochrm_NapC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48695">
        <property type="entry name" value="SSF48695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="8 10" id="KW-0408">Iron</keyword>
    <keyword evidence="7 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 8 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="17"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrom_NNT" evidence="12">
        <location>
            <begin position="15"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="binding site" description="covalent" evidence="9">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="9">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="9">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="9">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="10">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="10">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="9">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="9">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="10">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>3</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="9">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>4</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="9">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>4</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="10">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>4</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="10">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR000013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000013-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000013-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF03264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ41608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="191" mass="21776" checksum="87C2D43455448E0E" modified="2010-01-19" version="1">MKLLKTFWRRLKSPSKVAVGIVLFMGFMGGLLFWGAFNTGMEVTNTEEFCSGCHAPIVKEIKSTIHYSNRSGVRAICSDCHVPHNWTDKIVRKVQASKEIVAHMMGTIDTDEKFQARRAHLAEREWKRMKDNNSQECRNCHEFNYMDFSEQAPRSANQHSTALASGDKTCVDCHKGIAHKLPDMKNVEGWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZD6</accession>
    <name>D0YZD6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Esterase FrsA</fullName>
            <ecNumber evidence="1">3.1.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">frsA</name>
        <name evidence="2" type="ORF">VDA_002649</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the hydrolysis of esters.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a carboxylic ester + H2O = a carboxylate + an alcohol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21164"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29067"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:33308"/>
            <dbReference type="EC" id="3.1.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the FrsA family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.1" evidence="1"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300599.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002649"/>
    <dbReference type="ESTHER" id="lisda-d0yzd6">
        <property type="family name" value="Duf_1100-R"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41617">
        <property type="protein sequence ID" value="EEZ41617"/>
        <property type="gene ID" value="VDA_002649"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1073">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="721431at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080030">
        <property type="term" value="F:methyl indole-3-acetate esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01063">
        <property type="entry name" value="FrsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043423">
        <property type="entry name" value="FrsA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010520">
        <property type="entry name" value="FrsA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06500">
        <property type="entry name" value="FrsA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0719">Serine esterase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="420" mass="47116" checksum="795FC4882173BB86" modified="2010-01-19" version="1">MAESSKTNLSEKLFAPRANIKETSNLVKIAHSDTAVHNAIDGDSETGWYRVLRRPQWIWQGVDPIVLEEVLARITSTEAPRTDDALLDTVIGYRPGNWNYEWSQIAGRYHKQARYQASQGNQETAAELMFKSSIHYSIAAYPHIKGDELAAQAELHANQSYKEAIELRPHDMRTIDVKYEGKTFQAFIHLPRTDKLLPTVIVSGGLDTMQCDLWRLYTDYLGPAGFAMVTLDMPSVGYSARWSLTEDTSRLHQALLQQLRDVPWVDHHKVAMLGLRFGGNAAIRLGFLESARLKTCISLGGIIHSFFTQPKMLDQIPRMYLDVLASRLGKNGVSKTALLSHLPAWSLKNQGIVGRRPVGIPMLGLSLKNDPVCPESDNQLIAMSSYRGKAVTLPEKPLHDGYHRAMTMVVEWLNEKVLAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZI7</accession>
    <name>D0YZI7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Histidine--tRNA ligase</fullName>
            <ecNumber evidence="10">6.1.1.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Histidyl-tRNA synthetase</fullName>
            <shortName evidence="10">HisRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">hisS</name>
        <name evidence="12" type="ORF">VDA_002700</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>ATP + L-histidine + tRNA(His) = AMP + diphosphate + H(+) + L-histidyl-tRNA(His)</text>
            <dbReference type="Rhea" id="RHEA:17313"/>
            <dbReference type="Rhea" id="RHEA-COMP:9665"/>
            <dbReference type="Rhea" id="RHEA-COMP:9689"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78527"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.21"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3 10">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.21" evidence="10"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300737.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002700"/>
    <dbReference type="EnsemblBacteria" id="EEZ41668">
        <property type="protein sequence ID" value="EEZ41668"/>
        <property type="gene ID" value="VDA_002700"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0124">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="277998at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004821">
        <property type="term" value="F:histidine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006427">
        <property type="term" value="P:histidyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00773">
        <property type="entry name" value="HisRS-like_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00859">
        <property type="entry name" value="HisRS_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00127">
        <property type="entry name" value="His_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015807">
        <property type="entry name" value="His-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041715">
        <property type="entry name" value="HisRS-like_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004516">
        <property type="entry name" value="HisRS/HisZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033656">
        <property type="entry name" value="HisRS_anticodon"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43707">
        <property type="entry name" value="PTHR43707"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13393">
        <property type="entry name" value="tRNA-synt_His"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001549">
        <property type="entry name" value="His-tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00442">
        <property type="entry name" value="hisS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10 12" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 10 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="11">
        <location>
            <begin position="21"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ41668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="422" mass="47376" checksum="36FCD2D578355630" modified="2010-01-19" version="1">MAKQIQAIRGMNDCLPTQSPLWQKVEGTVKQVISSYGYNEVRMPIVESTHLFKRAIGEVTDVVEKEMYTFEDRNGDSLTLRPEGTAGCVRSGIQNGLLYNQEQRLWYIGPMFRHERPQKGRYRQFHQFGVEVFGLNGPDIDAELIMMTARLWRELGIHEHVTLELNSIGSLEARAEYRTALIAFLEQHMEVLDEDAKRRMYTNPLRVLDTKNPEIQNILGDAPKLSEYLDQDSREHFAGLCELLDAAGIKYQVNERLVRGLDYYNRTVFEWVTDSLGAQGTVCGGGRYDGLVEQLGGKVTPAVGFAMGLERLVLLMETLEQTEVRRSVDVYMVTAGEGTLAAGMKLAEVLRSQIPDLRVMTHFGGGNFKKQFKRADNVGAVVALVLGENEIAENTVVVKDLRGGEQITMNQDDVAAKLAELI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZM2</accession>
    <name>D0YZM2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphate-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_002735</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in the system for phosphate transport across the cytoplasmic membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Periplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the PstS family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002735"/>
    <dbReference type="EnsemblBacteria" id="EEZ41703">
        <property type="protein sequence ID" value="EEZ41703"/>
        <property type="gene ID" value="VDA_002735"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042301">
        <property type="term" value="F:phosphate ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024370">
        <property type="entry name" value="PBP_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011862">
        <property type="entry name" value="Phos-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12849">
        <property type="entry name" value="PBP_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02136">
        <property type="entry name" value="ptsS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0574">Periplasm</keyword>
    <keyword evidence="4" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="3 4" id="KW-0732">Signal</keyword>
    <keyword evidence="2 4" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5027157139" description="Phosphate-binding protein" evidence="4">
        <location>
            <begin position="25"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="PBP_domain" evidence="5">
        <location>
            <begin position="72"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="362" mass="39860" checksum="D1EE185FCB41DA7F" modified="2010-01-19" version="1">MKRGWRFSQIVAIGILGYCSAAFTQNLTTSPLDVQSAQLGSYSSENRTANQPSTTNEALTLLLPHYHRVSGISGNLSSSGSDTLANLMTYWAEEFKRRYPNVHIQIQTAGSSTAPTALTEATAQLGPMSRQMKTKEIEAFEHEYGYPPTEIRVAIDTLAVFVHEDNPLKGLNFKQLDAIYSRTYQCGAVETITRWGQLGLTGSWQHRPIQLFGRNSVSGTYGYFKKRALCRGDFRSNVNEQPGSASVAQSVSTSLNGIGYSGIGYKTTGIRAIPIAREGNEYVEATIDNSVSGHYPLARYLYVYVNKKPNKPLAPIVQEFFRFVLSQDGQQIVQKDGYVPVPQSVVEQDLIKLGLGHNSAAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZN4</accession>
    <name>D0YZN4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Penicillin-insensitive murein endopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002747</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300898.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002747"/>
    <dbReference type="MEROPS" id="M74.001"/>
    <dbReference type="EnsemblBacteria" id="EEZ41715">
        <property type="protein sequence ID" value="EEZ41715"/>
        <property type="gene ID" value="VDA_002747"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3770">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1681877at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009045">
        <property type="entry name" value="Hedgehog_sig/DD-Pept_Zn-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005073">
        <property type="entry name" value="Peptidase_M74"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03411">
        <property type="entry name" value="Peptidase_M74"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018455">
        <property type="entry name" value="MepA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55166">
        <property type="entry name" value="SSF55166"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="222"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="267" mass="29727" checksum="9A4AD844432CAA89" modified="2010-01-19" version="1">MGCLAGMCASVSASPWEKFKTPTQGEAQSIGSYANGCLAGGEALPLEGEGYQVIRSNRHRYYGNPELIEFLQQLTHASNQLKIGNVLIGDIAMARGGRFSSGHASHQTGLDADIWLKITDKPLDKSQLQTVSALPMVNLEQYKINKDNWTEKQAQLIQLAASDERVARIFVHPVIKETLCKEEWKDRSWLRKVRPWWGHYYHFHVRLNCPEGSQYCQAQTPPPPGDGCGAELASWRPKPVDKTKPTVKPKPKPKPVMPAQCKALLKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZN9</accession>
    <name>D0YZN9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Formate dehydrogenase formation protein FdhE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002752</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300907.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002752"/>
    <dbReference type="EnsemblBacteria" id="EEZ41720">
        <property type="protein sequence ID" value="EEZ41720"/>
        <property type="gene ID" value="VDA_002752"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3058">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="876348at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16341">
        <property type="entry name" value="FdhE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1670.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024064">
        <property type="entry name" value="FdhE-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006452">
        <property type="entry name" value="Formate_DH_accessory"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37689">
        <property type="entry name" value="PTHR37689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04216">
        <property type="entry name" value="FdhE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018296">
        <property type="entry name" value="Format_dh_formtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144020">
        <property type="entry name" value="SSF144020"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01562">
        <property type="entry name" value="FdhE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="296" mass="33474" checksum="F928681C34EDDB2C" modified="2010-01-19" version="1">MSVKILEKDMIIKQNSDGFTPLIIGQPTTIFTARAQRLRQLAQDSFMGDYLLLVGQIAQQQANLAEQFESQIQTFAAQQTPLWPLTFDNTWMPLLTKMLNTMLDALIPVVSEDMLAVLNEVKTLDNTTLEQYFSQLQQNQFDSVPSEQAILLFAVLNTFVSLYVAALRLEWQPELDKKQHNCPLCGAAPVASLVKDRGVRYLHCSQCEAQWHRLRAECTQCDDGEDIQLKSATLEDAVRAETCSHCNSYLKILFIEKDFKVEPIADDLATLVLDQKLAEDGLLRSGFNPYLLPLMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZQ6</accession>
    <name>D0YZQ6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Capsular polysaccharide synthesis enzyme CpsB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002769</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002769"/>
    <dbReference type="EnsemblBacteria" id="EEZ41737">
        <property type="protein sequence ID" value="EEZ41737"/>
        <property type="gene ID" value="VDA_002769"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5338">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018710" evidence="1">
        <location>
            <begin position="45"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="461" mass="53316" checksum="137A26714E204FC1" modified="2010-01-19" version="1">MVRRSNTVYQRGCQTIIMLRFKSNKIHLLLLSCLSATYAINASANITFQESKHIDPLLGLEFSSSVSSDYGYDDNVFNQNSDHIVGSNYYTIKPAFSITGHRYTKDFGLYYSGDYRKYTNDVTSYQGSSDQNYSDHNFNGIFKWEMGLRHHLELTANYGLGHEALGTGVTNGFYFDDNSPAEDVASFDNFQITKPIEKKDTDFAIKYSYGAKDAKGRIDFSVGQKRLRYDVLNSYSSTFQTYLENENLTESEMSLIFRHSYTHKTRFDYILMYRQYEYLDSTRDNEELLAGVSYISQITGKSKIEASITNVQKYMNTTDTSSINWSVMYKWQPVNYSAIVLKSASEVKEPDNTGDYIQSYINSISWNHEFLGNVSTQLSYTHIDDKYHIRDRNDDYDYLRLNVTYVFRPRVEFNFEYNYSVYNSSLNSDPLYINVISGPNLYGRNLGYEKNQFGLSIKVAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZS2</accession>
    <name>D0YZS2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Type I site-specific deoxyribonuclease</fullName>
            <ecNumber evidence="3">3.1.21.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">VDA_002785</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endonucleolytic cleavage of DNA to give random double-stranded fragments with terminal 5'-phosphates, ATP is simultaneously hydrolyzed.</text>
            <dbReference type="EC" id="3.1.21.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HsdR family.</text>
    </comment>
    <dbReference type="EC" id="3.1.21.3" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301001.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002785"/>
    <dbReference type="EnsemblBacteria" id="EEZ41753">
        <property type="protein sequence ID" value="EEZ41753"/>
        <property type="gene ID" value="VDA_002785"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0610">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="25184at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009035">
        <property type="term" value="F:type I site-specific deoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007409">
        <property type="entry name" value="Restrct_endonuc_type1_HsdR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040980">
        <property type="entry name" value="SWI2_SNF2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04313">
        <property type="entry name" value="HSDR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18766">
        <property type="entry name" value="SWI2_SNF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="8 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0680">Restriction system</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="12">
        <location>
            <begin position="292"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1309"/>
            <end position="1328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ41753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="1328" mass="152397" checksum="BDF66121567D4DDA" modified="2010-01-19" version="1">MSEYQLVEKPLLNQLKSMGWDVTDLGQGVPTDPTTSFRSSFREVILKDIFKAAVHRINTTDDSKPWLTDSQLDVLLDDVTDFGTHKLLAANEEFIGRLHKWQLDRNELTGEEDPVVKLIDFDNWDNNTFTAINQFRVDTPGLGKEHIRPDIVLFVNGLPLVVIECKEQSQHCCNPMAAGIDQLRRYADLREPEHSKLREGEPALFFTNQLMISTYGDDCKVGTITSNEDYYFNWKTIHPDTEPYIAPEIGTHRSQEKLVQGMLHPQRLLDITRCFTLFMDTDNGPRVKVICRYQQFRAVQKIIERMEQGETGIQRSGVVWHTQGSGKSLTMVFLVRKLRRHPELKSYKVLMVNDRSDLEEQLTNTAALIGDTVVEIKSTKDAKEKLANDTSNTNMVMVHKFREQDSSFLPESVRKLLSKHLAEAKEAGDVERIEELEADFDAEIVMHRPFGVINAGEKVLILVDEAHRTQRGGKDRPSLSDNLFDAFPKSTRVAFTGTPLIADHHTYPTWKRFGVSQEKAYIDKYKLQDAVDDGATLKILYEGKTADSAIYDKAGFDTKFEDLFSDRTEEELREIRKKYGAEGDILEAEKRIEEIAEDLVKHYIRQILPAGFKAQVVCSSKQAAIHYQTYIEKALAKEIERYKKQSEQCIDKAWLERLEFLKTAVVISSDDTNEAASFTYARKQAKELKAVESFKKKFDHSKPNTGVAFLIVCDMLLTGFDAPIEQVMYLDKKLREHNLLQTIARVNRTAKEKQRGYIVDYIGLAHHLRDALSMYSQDDQEDILESLQNIDSEVPVLESRYRRLLQLFTELKVHNIEAFVNQKLSIDEHYQVQLQAIAVLEDPRQRDSFNVFLKKFLQSMDIIMPNSLADPYKTPMYQFVHIQAKARQRYQDDSMSFQGVGAKIRHLVNEHLISLGINPKIKPIDLFSDAFMTHMGKEPDLQAQASEMEHAIRKHCKVNADDDPVFHKKMSEKLDEIIKKHSGNWEKMILELSALRDEIDAGRGPNAKVSDPFFDLIVSIAFPEGEPVKPLDKVKACVDAIMEELGENISSLDFWEREDLVSELRGRIKKRFILSKVPQLKEAREKLTIEVVALARRRELLILSDQALNQRIDEIIEKLRAIDPDALQKQISEQPDLSMLKYDLDGVDLYLAQELEQYESFYELGLIKVATDINYVEEAEHQSSLPYEVRKQFLLNAEDVREALADIILSIQSELTFPELEHQPIIALKETAKGSLFITVVIGLMTSLIYDVMKTTALKGRQPIKNIFSKSERVKTELPALVERNRAERGLEESSYGISYTEEKNLVDDALKQLRERNSPNQDKKKYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZS6</accession>
    <name>D0YZS6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002789</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301010.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41757">
        <property type="protein sequence ID" value="EEZ41757"/>
        <property type="gene ID" value="VDA_002789"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5033FJ9">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1474465at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="302" mass="36875" checksum="394CCF97B771265F" modified="2010-01-19" version="1">MHKYIINEYEFDIAIKYLKRHTRDYIKEELDYLSDEYLPLNKKIEKLEDIINSEQLKSDLIRIKRLIEDERITKSELLWIDSKNHRLCNYIYYILNNRRKLYLLNNTELDLPYLIDDESYEIDHDIYKNTIKTNSINHQEKYNSICEHIITSNFNKETKLNLIHVLKESWRSVSECKIITNFLNDKDINKCTWAVEYLKKNKKDRFDFEIISEEDYYDNVVLYFDTCDDKYKKELLITKMKKAWSQKKCRDAKNGFKYYSFNMKESINNKLSEMSRELNISKNLLVEKIIEKEYKQFKDNLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-08-12" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZT7</accession>
    <name>D0YZT7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Trp operon repressor homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">trpR</name>
        <name evidence="6" type="ORF">VDA_002800</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TrpR family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301042.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002800"/>
    <dbReference type="EnsemblBacteria" id="EEZ41768">
        <property type="protein sequence ID" value="EEZ41768"/>
        <property type="gene ID" value="VDA_002800"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2973">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1926997at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00475">
        <property type="entry name" value="Trp_repressor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000831">
        <property type="entry name" value="Trp_repress"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013335">
        <property type="entry name" value="Trp_repress_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010921">
        <property type="entry name" value="Trp_repressor/repl_initiator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038116">
        <property type="entry name" value="TrpR-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38025">
        <property type="entry name" value="PTHR38025"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01371">
        <property type="entry name" value="Trp_repressor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003196">
        <property type="entry name" value="Trp_repressor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48295">
        <property type="entry name" value="SSF48295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01321">
        <property type="entry name" value="TrpR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0678">Repressor</keyword>
    <keyword evidence="4 5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 5" id="KW-0805">Transcription regulation</keyword>
    <feature type="DNA-binding region" evidence="5">
        <location>
            <begin position="62"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="105" mass="11889" checksum="C8D01894821B3967" modified="2010-01-19" version="1">MSTTPETPDFTQWQQVIDLLRQAATEQKEDALLQLLLTPDERDALLARVNIVHELLNGQRSQRKISELLGVGVATITRGSNELKHQDEATKAWIGEQLKQMVDKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZW9</accession>
    <name>D0YZW9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribosome-binding factor A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rbfA</name>
        <name evidence="3" type="ORF">VDA_002832</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RbfA family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301142.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002832"/>
    <dbReference type="EnsemblBacteria" id="EEZ41800">
        <property type="protein sequence ID" value="EEZ41800"/>
        <property type="gene ID" value="VDA_002832"/>
    </dbReference>
    <dbReference type="GeneID" id="57340886"/>
    <dbReference type="eggNOG" id="COG0858">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1971380at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00003">
        <property type="entry name" value="RbfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000238">
        <property type="entry name" value="RbfA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023799">
        <property type="entry name" value="RbfA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020053">
        <property type="entry name" value="Ribosome-bd_factorA_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33515">
        <property type="entry name" value="PTHR33515"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02033">
        <property type="entry name" value="RBFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89919">
        <property type="entry name" value="SSF89919"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00082">
        <property type="entry name" value="rbfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01319">
        <property type="entry name" value="RBFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0690">Ribosome biogenesis</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="133" mass="15348" checksum="462B3AE9308353E4" modified="2010-01-19" version="1">MAKEFSRTQRVAQQLQKELAVILQRELKEPRLAMTTISSVEVSRDMGYAKVYVTFFAIGDQSEEESLAILREKAPYIRSLLGKQIRLRVTPELTFIFDQSLTEGMRISNLVSKVVRDDEVRHVADDDQKQDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z024</accession>
    <name>D0Z024_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Radical SAM core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_002887</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301274.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002887"/>
    <dbReference type="EnsemblBacteria" id="EEZ41855">
        <property type="protein sequence ID" value="EEZ41855"/>
        <property type="gene ID" value="VDA_002887"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1242">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="979208at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039661">
        <property type="entry name" value="ELP3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032432">
        <property type="entry name" value="Radical_SAM_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005911">
        <property type="entry name" value="YhcC-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11135">
        <property type="entry name" value="PTHR11135"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11135:SF1">
        <property type="entry name" value="PTHR11135:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16199">
        <property type="entry name" value="Radical_SAM_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01091">
        <property type="entry name" value="uncharacterized_CHP01210-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01212">
        <property type="entry name" value="TIGR01212"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="7">
        <location>
            <begin position="17"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ41855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="309" mass="34609" checksum="661E6460F8720885" modified="2010-01-19" version="1">MQLHERVNTFGQDLQRRYGEKVHKLTLHGGFSCPNRDGTIGRGGCTFCNVASFADEKAQFLPIHEQLTQRAGEVNRAKKYLAYFQAYTSTYAEVQTLKKMYEEALQAADIVGLCVGTRPDCVPDAVLDLLAGYREQGYEIWLELGLQTANDKTLKRINRGHDFACYAEITRRARALGIKVCTHLIVGLPGDTKQDNLETIKRVVEVGVDGIKLHPLHLVEGSKLGQAWKAGRIEEVSLDQYSDIASEMIRLTPPDVVYHRVSASARKPTLLAPSWCETRWLVMTEIWRNLEQFGAQGSGVGAPFVYQKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z059</accession>
    <name>D0Z059_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002922</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301363.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002922"/>
    <dbReference type="EnsemblBacteria" id="EEZ41890">
        <property type="protein sequence ID" value="EEZ41890"/>
        <property type="gene ID" value="VDA_002922"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502Z8UB">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1178526at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032811">
        <property type="entry name" value="Put_conjugal_transfer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13729">
        <property type="entry name" value="TraF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018720" evidence="1">
        <location>
            <begin position="24"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="399" mass="43376" checksum="84B481716CEBCB63" modified="2010-01-19" version="1">MFFCKRNHLALLVLSSLSASAFADNGMDARGMGMGGTGVASAHYLTAGFYNPALAVNYKANDDFGLMLPSIGVTVHDADDLYHKVDHFQEINSDIEDSIDNGMLTAAQKEEWTSALNELDNGSLKATVHAGIAASVPNHYLSAVLFTQAQVQAVVNTDIDQRDIKHLEDFDTTPEHMYSTVEGLAGGTADIGIALAKSFDLPFDNQTVSLGVAPKLQKIYALRYKKTVEEFEDSDFDAGHDHTEKTAFNLDLGIAYKPVDSITVAFAAKNVIKQSLDTNQNISRSDSTAVTYLVEPKYTAGVAYDNGMFTLAADVDLNKQHYFEELAYETQFAHLGAEFNAWDWAQLRAGYSISMTDYAQNMVTAGIGLKPFGAFGIDLAGQYGEDNNYGAAVQFVITL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z081</accession>
    <name>D0Z081_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_002944</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301394.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002944"/>
    <dbReference type="EnsemblBacteria" id="EEZ41912">
        <property type="protein sequence ID" value="EEZ41912"/>
        <property type="gene ID" value="VDA_002944"/>
    </dbReference>
    <dbReference type="GeneID" id="57340749"/>
    <dbReference type="eggNOG" id="COG0306">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1329125at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:inorganic phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001204">
        <property type="entry name" value="Phos_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11101">
        <property type="entry name" value="PTHR11101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01384">
        <property type="entry name" value="PHO4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="49"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="149"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="184"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="217"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="257"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="305"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="345"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="371"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="396"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="422" mass="43977" checksum="6E3B9E50B760EB3A" modified="2010-01-19" version="1">MEILANYGSLIIGVAAIFGLLMAIGIGANDVANAMGTSVGSKALTVKQAIIIAMIFEFAGAYLAGGEVTDTIRKGVIETSLYAHQPEILVYGMMSALLAAGTWLLVASYMGWPVSTTHSIIGAIIGFACVSVGTDAVDWHSIQGIVGSWLITPLIAGIFAYFIFISAQRLIFDTDKPLVNAKRFVPVYMFITAMVIALVTIKKGLKHVGLHLTNGEAWVASLVVSLLVMVFGYFYIQRKYKDNDNVVSSNGYAGVESVFSVLMVVTACAMAFAHGSNDVANAIGPLSAIVSTVQHGGQIADKAEIAWWILPLGGIGIVVGLATLGHKVMATVGTGITELTPSRGFAAQLATASTVVLASGTGLPISTTQTLVGAVLGVGFARGIAALNLGVVRNIVASWVVTLPAGALLAVVFYYVMRAVFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z090</accession>
    <name>D0Z090_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">GatB/Yqey</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002953</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301412.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002953"/>
    <dbReference type="EnsemblBacteria" id="EEZ41921">
        <property type="protein sequence ID" value="EEZ41921"/>
        <property type="gene ID" value="VDA_002953"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1610">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1498741at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016884">
        <property type="term" value="F:carbon-nitrogen ligase activity, with glutamine as amido-N-donor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1510.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003789">
        <property type="entry name" value="Asn/Gln_tRNA_amidoTrase-B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023168">
        <property type="entry name" value="GatB_Yqey_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019004">
        <property type="entry name" value="YqeY/Aim41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042184">
        <property type="entry name" value="YqeY/Aim41_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28055">
        <property type="entry name" value="PTHR28055"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09424">
        <property type="entry name" value="YqeY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89095">
        <property type="entry name" value="SSF89095"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="147" mass="15992" checksum="5260E1856B1C527C" modified="2010-01-19" version="1">MTLIERLKDEQKAAMKARDKARLGAIRLALAAIKQREVDEKITLTDDDIVAVLTKMVKQRRDSVAQYEAAGRQDLADVELAEISVLEEFMPQPLSDDEVAALLDEAIAATGAAGMQDMGKVMGVLKPQIQGRADMGKVSQLVKTKLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z097</accession>
    <name>D0Z097_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002960</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41928">
        <property type="protein sequence ID" value="EEZ41928"/>
        <property type="gene ID" value="VDA_002960"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="49" mass="5864" checksum="64C8AE4B1C5E0656" modified="2010-01-19" version="1">MLTDEFAHQMTAKLYLATPHQLDDVEQHDHLDAQFEYECDEQYEIRVVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0I4</accession>
    <name>D0Z0I4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">Fumarate reductase iron-sulfur subunit</fullName>
            <ecNumber evidence="3 11">1.3.5.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">VDA_003048</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>a menaquinone + succinate = a menaquinol + fumarate</text>
            <dbReference type="Rhea" id="RHEA:27834"/>
            <dbReference type="Rhea" id="RHEA-COMP:9537"/>
            <dbReference type="Rhea" id="RHEA-COMP:9539"/>
            <dbReference type="ChEBI" id="CHEBI:16374"/>
            <dbReference type="ChEBI" id="CHEBI:18151"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="EC" id="1.3.5.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a quinone + succinate = a quinol + fumarate</text>
            <dbReference type="Rhea" id="RHEA:40523"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.3.5.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="11">Binds 1 [2Fe-2S] cluster.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </cofactor>
        <text evidence="11">Binds 1 [3Fe-4S] cluster.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="11">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.</text>
    </comment>
    <dbReference type="EC" id="1.3.5.4" evidence="3 11"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301689.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003048"/>
    <dbReference type="EnsemblBacteria" id="EEZ42015">
        <property type="protein sequence ID" value="EEZ42015"/>
        <property type="gene ID" value="VDA_003048"/>
    </dbReference>
    <dbReference type="GeneID" id="57340477"/>
    <dbReference type="eggNOG" id="COG0479">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1605514at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051538">
        <property type="term" value="F:3 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102040">
        <property type="term" value="F:fumarate reductase (menaquinone)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004489">
        <property type="entry name" value="Succ_DH/fum_Rdtase_Fe-S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025192">
        <property type="entry name" value="Succ_DH/fum_Rdtase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13085">
        <property type="entry name" value="Fer2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13183">
        <property type="entry name" value="Fer4_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00384">
        <property type="entry name" value="dhsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="9 11" id="KW-0003">3Fe-4S</keyword>
    <keyword evidence="11" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7 11" id="KW-0408">Iron</keyword>
    <keyword evidence="8 11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="12">
        <location>
            <begin position="7"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="13">
        <location>
            <begin position="139"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEZ42015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="246" mass="27462" checksum="9C6F4FB3875AEEA3" modified="2010-01-19" version="1">MADNRIQKVDILRYDPEHDAEPYLETFEVPFNETMSVLDALGYIKDNLDKDLAYRWSCRMAICGSCGMMVNNVPKLACKTFLREYPEGLKIEPLANFAIEKDLIVDMTPFIERLEAIKPYIIGNGRTPEDGPNLQTPEQMAKYKQFAGCINCGLCYAACPQFGLNPEFIGPAALTLAHRYNLDSRDNGSQERMELINGENGAWGCTFVGYCSEVCPKHVDPAAAVNQGKVESSKDFVIAMLKPQEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0K7</accession>
    <name>D0Z0K7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Biotin carboxyl carrier protein of acetyl-CoA carboxylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_003071</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 5">This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301753.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003071"/>
    <dbReference type="EnsemblBacteria" id="EEZ42038">
        <property type="protein sequence ID" value="EEZ42038"/>
        <property type="gene ID" value="VDA_003071"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0511">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1938042at2"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009317">
        <property type="term" value="C:acetyl-CoA carboxylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003989">
        <property type="term" value="F:acetyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001249">
        <property type="entry name" value="AcCoA_biotinCC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001882">
        <property type="entry name" value="Biotin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01071">
        <property type="entry name" value="ACOABIOTINCC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00531">
        <property type="entry name" value="BCCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00188">
        <property type="entry name" value="BIOTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0092">Biotin</keyword>
    <keyword evidence="5" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="6">
        <location>
            <begin position="76"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ42038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="152" mass="16033" checksum="5AA6578D045E91C7" modified="2010-01-19" version="1">MDIRKIKKLIELVEESGIAELEISEGEESVRISRSTAPVVPAQQYYAPAQPAAPVAAPVQAAPAEAPVAAAPEVTGHKVLSPMVGTFYRSPSPEAAKFAEIGQSVSVGDTLCIVEAMKMMNQIQSDKAGTIVAILAKDGDAVEFDQPLFVIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0P4</accession>
    <name>D0Z0P4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Vitamin B12 transporter BtuB</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Cobalamin receptor</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Outer membrane cobalamin translocator</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">btuB</name>
        <name evidence="13" type="ORF">VDA_003108</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell outer membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301882.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003108"/>
    <dbReference type="EnsemblBacteria" id="EEZ42075">
        <property type="protein sequence ID" value="EEZ42075"/>
        <property type="gene ID" value="VDA_003108"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4206">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="71288at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046930">
        <property type="term" value="C:pore complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015420">
        <property type="term" value="F:ABC-type vitamin B12 transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015288">
        <property type="term" value="F:porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01531">
        <property type="entry name" value="BtuB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010101">
        <property type="entry name" value="B12_transptr_BtuB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039426">
        <property type="entry name" value="BtuB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010917">
        <property type="entry name" value="TonB_rcpt_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30069">
        <property type="entry name" value="PTHR30069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01156">
        <property type="entry name" value="TONB_DEPENDENT_REC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="5 10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 10" id="KW-0626">Porin</keyword>
    <keyword evidence="13" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0732">Signal</keyword>
    <keyword evidence="6 10" id="KW-0798">TonB box</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 10" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="1 10" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5009009110" description="Vitamin B12 transporter BtuB" evidence="10">
        <location>
            <begin position="24"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="12">
        <location>
            <begin position="45"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="11">
        <location>
            <begin position="192"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="TonB box" evidence="10">
        <location>
            <begin position="31"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="TonB C-terminal box" evidence="10">
        <location>
            <begin position="592"/>
            <end position="609"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ42075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="609" mass="67640" checksum="2042CCE4E31C0ECE" modified="2010-01-19" version="1" precursor="true">MKKSFLAVSVATLCSSFAPLAFAADDVDSNDVMVVTANRFAQPLKTVIAPISVVTKEEIDAIQAKSMAEVLRLLPGVQVVSGGLGQNTEVYVRGTSSKHLLVMINGVRIGSATLGSADFSQIPLTGIERIELIRGSRAALYGSDAIGGVLNIITAYQPGEQQVQATVSGGSEGYYQVGASAAGQIGTEGWGKLAIRTEGNDGFSARQLPYEQDKDGFTSKNAVAELGRHLGDNWKVSLQGYFHKGKNKYDDADFFGNNKPNPKAENELYNIAGKVNYSTAQYSSELTLAQNQDKAKNYNDIEVGSEIKTTRLLANWQNHYQVNENWQIGGGTEWHRDKVSNSTQQYSKDQRDNTAFYLTSIYKLQDWQFEGSARTDDNQSYGRHNTWQLGSSYQITPEVKSYASVGTAFKAPTFNDLYWPASGNPDLQPEESTNYELGLSGHHQLLDWSVTAYRNDIDQLIAWAPNATGMWIPQNVAKAKIKGVELTTGFATGPIYHDISYDYLEPEDAATGNQLIRRSKHNAKWRMSYLLDDWQFDVNTIYHGSSYEDATNKQKMDAYTLVDLAASYYMTEHLTLRGRIGNLFDADYQTRTSYNTPERTYYATATYQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0U9</accession>
    <name>D0Z0U9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="14">HemY-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">VDA_003163</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in a late step of protoheme IX synthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Porphyrin-containing compound metabolism; protoheme biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell inner membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302048.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003163"/>
    <dbReference type="EnsemblBacteria" id="EEZ42130">
        <property type="protein sequence ID" value="EEZ42130"/>
        <property type="gene ID" value="VDA_003163"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3071">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="699592at2"/>
    <dbReference type="UniPathway" id="UPA00252"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042168">
        <property type="term" value="P:heme metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006779">
        <property type="term" value="P:porphyrin-containing compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005254">
        <property type="entry name" value="Heme_biosyn_assoc_TPR_pro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010817">
        <property type="entry name" value="HemY_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013105">
        <property type="entry name" value="TPR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07219">
        <property type="entry name" value="HemY_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07719">
        <property type="entry name" value="TPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00540">
        <property type="entry name" value="TPR_hemY_coli"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="7 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="40"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="HemY_N" evidence="13">
        <location>
            <begin position="26"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="327"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF07219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEZ42130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="395" mass="43682" checksum="C6C30C1CC3A83A1C" modified="2010-01-19" version="1">MIKLLLLIAALIAGIVVGPDLAGSQGYVLISFAEQTIEMSLTTLVILIVALLALFFVVEFILRGLFSMGSSTRGWFSQRKARKARTLTADGLVKVIEGDWKQAEKLVTKAAKNSDAPVLNYLAAAEASQELGNTDQRDEYLKRAAECDGQNLAVGLVRAKLQIRQQQYEQALATLQEIKRDNGRNLIVLNLLKECYIQLEDWKALLEILPQLEKDGVITTETKNQLELDAQRGLMVQIAKQSGSDGLMSHWNGLNRKLKQQSVLVAAFVEQMINCNADNDAYTVLREYLKKTSDDTLINLVPKLKLSDNHPAIVRLQDLLRHDSRNAATHSALGQMFAANGKWQEAKEHFTQAVALRPDVSDYAHLVQTLENLDDSQGAAQASLQALNLALPAKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0V1</accession>
    <name>D0Z0V1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribosomal RNA small subunit methyltransferase J</fullName>
            <ecNumber evidence="1">2.1.1.242</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">16S rRNA m2G1516 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">rRNA (guanine-N(2)-)-methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rsmJ</name>
        <name evidence="2" type="ORF">VDA_003165</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Specifically methylates the guanosine in position 1516 of 16S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>guanosine(1516) in 16S rRNA + S-adenosyl-L-methionine = H(+) + N(2)-methylguanosine(1516) in 16S rRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:43220"/>
            <dbReference type="Rhea" id="RHEA-COMP:10412"/>
            <dbReference type="Rhea" id="RHEA-COMP:10413"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74481"/>
            <dbReference type="EC" id="2.1.1.242"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. RsmJ family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.242" evidence="1"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302053.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003165"/>
    <dbReference type="EnsemblBacteria" id="EEZ42132">
        <property type="protein sequence ID" value="EEZ42132"/>
        <property type="gene ID" value="VDA_003165"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0742">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1696461at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008990">
        <property type="term" value="F:rRNA (guanine-N2-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01523">
        <property type="entry name" value="16SrRNA_methyltr_J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007536">
        <property type="entry name" value="16SrRNA_methylTrfase_J"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36112">
        <property type="entry name" value="PTHR36112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04445">
        <property type="entry name" value="SAM_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="1 2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="1">
        <location>
            <begin position="101"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="1">
        <location>
            <begin position="117"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="1">
        <location>
            <begin position="153"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="257" mass="27974" checksum="B9E59883D9BCD45B" modified="2010-01-19" version="1">MHIALICEAPERQSELDTLAQRWGLHHDDSSEFALVLTTEQLELRKLDEPKLGAVFVDLAGGAVAHRRKFGGGRGQAIAKAVGLKSGVNPIVLDGTAGLGRDAFVLASLGCTVYMVERHPVVAALLDDGLQRAQNDSEIGTWVGDRMHLLHASSHDALYQLAEQDGFVAPDVVYLDPMFPHKKKSALVKKEMRVFQTLVGADLDADALFAPAMALATKRVVVKRPDYAEFLAGEQPSMAIETKKNRFDVYVKSGMKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0W5</accession>
    <name>D0Z0W5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ATP-dependent RNA helicase RhlB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_003179</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the DEAD box helicase family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003179"/>
    <dbReference type="EnsemblBacteria" id="EEZ42146">
        <property type="protein sequence ID" value="EEZ42146"/>
        <property type="gene ID" value="VDA_003179"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0513">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4 8" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="6">
        <location>
            <begin position="1"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="7">
        <location>
            <begin position="150"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="304"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="309"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ42146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="339" mass="38622" checksum="7D16FB2A8998ED01" modified="2010-01-19" version="1">MAIQIYNDAAPLIASTGLTAGLAYGGEPYEKQQKKLTDGVDILIGTCGRIIDFYKQRVIDLRSIQAVVLDEADRMFDLGFIKDIRFLFRRMPAPDQRRNMLFSATLSYRVKELAFEHMNTPESVVVEPEQKTGHRIQEELFYPSNNDKMRLLQTLIEEEWPDRAIIFANTKHRCEDVWGHLAADGHRVGLLTGDVPQKKRVRILEQFTQGDIDILVATDVAARGLHIPQVTHVFNYDLPDDCEDYVHRIGRTGRAGASGHSISFACEEYAINLPGIETYIEHSIPLSKYDASALLEDLPEPIRITRTPRQGGRRSNQQGQGQSRQRNRRRPAQKKQQQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0X4</accession>
    <name>D0Z0X4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative peptide ABC transporter permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_003188</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302110.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003188"/>
    <dbReference type="EnsemblBacteria" id="EEZ42155">
        <property type="protein sequence ID" value="EEZ42155"/>
        <property type="gene ID" value="VDA_003188"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1173">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1734230at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025966">
        <property type="entry name" value="OppC_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12911">
        <property type="entry name" value="OppC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="29"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="105"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="167"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="222"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="277"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="99"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ42155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="313" mass="34685" checksum="AC3DA402065718DF" modified="2010-01-19" version="1">MSEQVITTPSRWQRFKQSDFLYFFRKDKVAMVSFAIFMAFATMAVFAPFIAPTNPYDLSSIDIMDAELPPSWMDEGDERFTLGTDDQGRDIFSTILYGSRLSLTIGLLAVGLQLILGVIIGLSAGYFGGRIDNFLMRIADVQLSFSTMMVAIIISAIFRTALGSELYAQYAVVMLVVIIGIAEWPQYARTIRASVLAEKKKEYVEAAKVMGFRAPRIMFRHILPNCLSPILVISTVQVANAIMSEAALSFLGLGLPVDQPSLGSLISIGFNYIFSGAWWITAFPGLVLVVLVLVINLLGDWLRDVFNPKIYKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0Y6</accession>
    <name>D0Z0Y6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Zn-finger domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302142.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003200"/>
    <dbReference type="EnsemblBacteria" id="EEZ42167">
        <property type="protein sequence ID" value="EEZ42167"/>
        <property type="gene ID" value="VDA_003200"/>
    </dbReference>
    <dbReference type="GeneID" id="57340392"/>
    <dbReference type="eggNOG" id="COG0551">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1276290at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003917">
        <property type="term" value="F:DNA topoisomerase type I (single strand cut, ATP-independent) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000380">
        <property type="entry name" value="Topo_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013498">
        <property type="entry name" value="Topo_IA_Znf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42785">
        <property type="entry name" value="PTHR42785"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01396">
        <property type="entry name" value="zf-C4_Topoisom"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="zf-C4_Topoisom" evidence="1">
        <location>
            <begin position="16"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="domain" description="zf-C4_Topoisom" evidence="1">
        <location>
            <begin position="63"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="zf-C4_Topoisom" evidence="1">
        <location>
            <begin position="107"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="185" mass="20899" checksum="3E070CAF90F75268" modified="2010-01-19" version="1">MSHSSLFSNHEHALTQTCPQCGEPLQMRFGKHGPFLGCSHYPECDYIQPLKQNDGHIVKLLGVPCPKCQQELVLRQGRFGMFIGCSSYPQCDYISSPEKPAEETHIACPECKTGHLVERKSRYGKLFYACDQYPRCRFAVNNKPVIGECQSCHYPLLIEKKLAAGVKLQCANRHCQAYQDSTDTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z156</accession>
    <name>D0Z156_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Usp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003270</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003270"/>
    <dbReference type="EnsemblBacteria" id="EEZ42237">
        <property type="protein sequence ID" value="EEZ42237"/>
        <property type="gene ID" value="VDA_003270"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0589">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="1">
        <location>
            <begin position="12"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="90" mass="10162" checksum="392129FAE96E0AB1" modified="2010-01-19" version="1">MDVELELDEVHNALEIKRMQQLADLAKQSPYPVGEMYLADGDVAKHLVELAKKVDAKLVIVGYHKTFLHLFGDVADELSKHLECDVLTCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z175</accession>
    <name>D0Z175_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Putrescine transporter PotE</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Putrescine-proton symporter / putrescine-ornithine antiporter</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">potE</name>
        <name evidence="6" type="ORF">VDA_003289</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes both the uptake and excretion of putrescine. The uptake of putrescine is dependent on the membrane potential and the excretion involves putrescine-ornithine antiporter activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>H(+)(in) + putrescine(in) = H(+)(out) + putrescine(out)</text>
            <dbReference type="Rhea" id="RHEA:28891"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:326268"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-ornithine(out) + putrescine(in) = L-ornithine(in) + putrescine(out)</text>
            <dbReference type="Rhea" id="RHEA:28827"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="ChEBI" id="CHEBI:326268"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell inner membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003289"/>
    <dbReference type="EnsemblBacteria" id="EEZ42256">
        <property type="protein sequence ID" value="EEZ42256"/>
        <property type="gene ID" value="VDA_003289"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0531">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015496">
        <property type="term" value="F:putrescine:ornithine antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02073">
        <property type="entry name" value="Putrescine_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027566">
        <property type="entry name" value="Symport/antiport_PotE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="5" id="KW-0050">Antiport</keyword>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0769">Symport</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="106"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="135"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="175"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="206"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="252"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="302"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="336"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="370"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="393"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ42256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="423" mass="44910" checksum="CBC7761B9E086581" modified="2010-01-19" version="1">MAVNMMGSGIIMLPASLAQVGAISMLSWVVTALGAMCIAYTFAKCGALCKRSGGMSAYSEEAHGKSSFFISSYTYYVCLVISCVAIAVSAVGYIKPFMPWLDTPVHTFFGVCAVLILTMVANFGGAKITGQISSFTVWGIIIPVFGLSIIGWWWFDPQTFMNAWNPHHDTTMHSVSSGIALTLWAFLGIESAGANSDAVENPERNVPLAVLFGTSFAAIVYILSTGVIQGIIPNAELAASTAPFGLVFSHMFNPMVGNIVTLAAVIACIGSLLGWQFTNAQVSKAAADEGLFPKIFAKTNSAGAPIAGMLIMLAGELILAVMTISPDLINQFNSLLNLAVFINMVPYILSMTGLEVMLRKNMVSPKQYRLGAVVGTLAVIYSIYGVYACGMEAVFGGTILTLFGYIFYGFIAARDVNPGVKAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1D7</accession>
    <name>D0Z1D7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative lipopolysaccharide biosynthesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003351</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003351"/>
    <dbReference type="EnsemblBacteria" id="EEZ42318">
        <property type="protein sequence ID" value="EEZ42318"/>
        <property type="gene ID" value="VDA_003351"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0859">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03789">
        <property type="entry name" value="GT9_LPS_heptosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002201">
        <property type="entry name" value="Glyco_trans_9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01075">
        <property type="entry name" value="Glyco_transf_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="377" mass="42121" checksum="CD0B509F240F28C0" modified="2010-01-19" version="1">MICTSYLHQWQSEYFTISSSNCIICVNSSVENRFMALFSAQPQSICILRLSAIGDVCHAISVVQAIQKHWPKTKITWVCGKIEAQLIGDLPNIRVVIFDKKAGYKGMKSVWQQLKSERFDALLDMQVALRASALSLGIKAKYRIGFSKNRTKEGQWWFTNRHLPDTQSFHVLDNFADFARYLGVPFTTPSWHIPQSKDDIQFAQAHIQQPTLIISPAASKDERNWLTERYAAIADYAQEKQLQVILCGSPAAREVKLGEDICALCNHKPLNLIGKTSLKQLTALLGQATVVIAPDTGPAHLATTQLTPVIGLYAHSNPQRTGPYNSLDTVVSVYDQFAQQQYGKSVAELPWGTRVKGDNLMQAITVDAVIEQLNKFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1J9</accession>
    <name>D0Z1J9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 10 11">Ribulose-phosphate 3-epimerase</fullName>
            <ecNumber evidence="7 10 11">5.1.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">rpe</name>
        <name evidence="15" type="ORF">VDA_003413</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10 11">
            <text>D-ribulose 5-phosphate = D-xylulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:13677"/>
            <dbReference type="ChEBI" id="CHEBI:57737"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="EC" id="5.1.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10 13">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="10 13">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="10">Carbohydrate degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 10 11">Belongs to the ribulose-phosphate 3-epimerase family.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.1" evidence="7 10 11"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302667.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003413"/>
    <dbReference type="EnsemblBacteria" id="EEZ42380">
        <property type="protein sequence ID" value="EEZ42380"/>
        <property type="gene ID" value="VDA_003413"/>
    </dbReference>
    <dbReference type="GeneID" id="57340136"/>
    <dbReference type="eggNOG" id="COG0036">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1697639at2"/>
    <dbReference type="UniPathway" id="UPA00705"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004750">
        <property type="term" value="F:D-ribulose-phosphate 3-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019323">
        <property type="term" value="P:pentose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00429">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02227">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026019">
        <property type="entry name" value="Ribul_P_3_epim"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000056">
        <property type="entry name" value="Ribul_P_3_epim-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11749">
        <property type="entry name" value="PTHR11749"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00834">
        <property type="entry name" value="Ribul_P_3_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001461">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01163">
        <property type="entry name" value="rpe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01085">
        <property type="entry name" value="RIBUL_P_3_EPIMER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01086">
        <property type="entry name" value="RIBUL_P_3_EPIMER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="13" id="KW-0170">Cobalt</keyword>
    <keyword evidence="9 10 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="13" id="KW-0464">Manganese</keyword>
    <keyword evidence="8 10 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="10 14">
        <location>
            <begin position="144"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="177"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10 14">
        <location>
            <begin position="199"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10 12">
        <location>
            <position position="36"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10 12">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10 14">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 13">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 13">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 13 14">
        <location>
            <position position="68"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10 13">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00009541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR001461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEZ42380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="224" mass="24788" checksum="F00578A4623A3158" modified="2010-01-19" version="1">MKDFLIAPSILSADFARLGEDVEKVLASGADVVHFDVMDNHYVPNLTFGAPICQALRNYGIDAPIDVHLMVKPVDRIIPDFAKAGASMITFHVEATEHLDRTLQLIKEHGCKAGVVFNPATPLHHLDYIMDKIDMILLMSVNPGFGGQSFIPATLDKLREVRRRIDESGYDIRLEIDGGVKVDNIREIAEAGADMFVAGSAIFGQPDYKEVIDQMRAELAKVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1K8</accession>
    <name>D0Z1K8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cyclic AMP receptor protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_003422</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003422"/>
    <dbReference type="EnsemblBacteria" id="EEZ42389">
        <property type="protein sequence ID" value="EEZ42389"/>
        <property type="gene ID" value="VDA_003422"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0664">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018488">
        <property type="entry name" value="cNMP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012318">
        <property type="entry name" value="HTH_CRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018335">
        <property type="entry name" value="Tscrpt_reg_HTH_Crp-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13545">
        <property type="entry name" value="HTH_Crp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00034">
        <property type="entry name" value="HTHCRP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00419">
        <property type="entry name" value="HTH_CRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00888">
        <property type="entry name" value="CNMP_BINDING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00889">
        <property type="entry name" value="CNMP_BINDING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00042">
        <property type="entry name" value="HTH_CRP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51063">
        <property type="entry name" value="HTH_CRP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0675">Receptor</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="2">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="HTH crp-type" evidence="3">
        <location>
            <begin position="109"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ42389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="181" mass="20276" checksum="EED540BD750612E1" modified="2010-01-19" version="1">MIHAGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEGQERTAWVRAKTPCEVAEISFKKFRQLIQVNPDILMRLSAQMARRLQVTSQKVGDLAFLDVTGRIAQTLLNLAKQPDAMTHPDGMQIKITRQEIGQIVGCSRETVGRILKMLEEQNLISAHGKTIVVYGTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1P4</accession>
    <name>D0Z1P4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5 7">50S ribosomal protein L15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplO</name>
        <name evidence="10" type="ORF">VDA_003458</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Binds to the 23S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uL15 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302825.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003458"/>
    <dbReference type="EnsemblBacteria" id="EEZ42425">
        <property type="protein sequence ID" value="EEZ42425"/>
        <property type="gene ID" value="VDA_003458"/>
    </dbReference>
    <dbReference type="GeneID" id="57340085"/>
    <dbReference type="eggNOG" id="COG0200">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1874945at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01341">
        <property type="entry name" value="Ribosomal_L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036227">
        <property type="entry name" value="L18e/L15P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030878">
        <property type="entry name" value="Ribosomal_L15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005749">
        <property type="entry name" value="Ribosomal_L15_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001196">
        <property type="entry name" value="Ribosomal_L15_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021131">
        <property type="entry name" value="Ribosomal_L18e/L15P"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12934">
        <property type="entry name" value="PTHR12934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00828">
        <property type="entry name" value="Ribosomal_L27A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52080">
        <property type="entry name" value="SSF52080"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01071">
        <property type="entry name" value="rplO_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00475">
        <property type="entry name" value="RIBOSOMAL_L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L18e/L15P" evidence="9">
        <location>
            <begin position="28"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ42425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="144" mass="14880" checksum="94950372DE497B8C" modified="2010-01-19" version="1">MRLNTLSPAAGSKPSAKRVGRGIGSGLGKTCGRGHKGQKSRSGGSVRPGFEGGQMPLKQRLPKFGFTSRKGLVSAEIRLAELAKVEGDVVSLETLKAADLISANIQFAKVVLSGEINRAVTVKGLRVTKGAKAAIEAAGGKIEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z282</accession>
    <name>D0Z282_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF2760 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001927</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001927"/>
    <dbReference type="EnsemblBacteria" id="EEZ40895">
        <property type="protein sequence ID" value="EEZ40895"/>
        <property type="gene ID" value="VDA_001927"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5032SHU">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021212">
        <property type="entry name" value="DUF2760"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10816">
        <property type="entry name" value="DUF2760"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2760" evidence="1">
        <location>
            <begin position="86"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="209" mass="23174" checksum="3DDBE870A76FD83E" modified="2010-01-19" version="1">MVHVGLGALVLILLVMYIAKKGKPVEVEKIVEKEVEVEKIVEVEKPVEKIIEKIVEKPVEKIVEVEKVVEKIVEVEVEPKLKTSTPDSALQLLSLLQQEARFIDFMQEDLKGFSDADIGAAARVVHEGGHKVINEYFTFAPVRSEDEETRITLPQGFNASEVRLTGNVVGEAPFNGTLIHRGWKVTEVKLPKLAEGHDAHIVAAAEVEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2D4</accession>
    <name>D0Z2D4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000585</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304777.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000585"/>
    <dbReference type="EnsemblBacteria" id="EEZ39565">
        <property type="protein sequence ID" value="EEZ39565"/>
        <property type="gene ID" value="VDA_000585"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031PAH">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1765730at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="77"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="121"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="314" mass="36188" checksum="373F8DDFD41D5CAB" modified="2010-01-19" version="1">MKSSPYNSQHIPPQAPGDGQGFWSQQARKGTYFPFTRNNHHVPEKELLYQKPSELRKLTSFDDGYNERQIREITLPWWGLIYFYAVTFAKGTALIMMPMAFLVFGGMNLSDDSIQSDFNQIYFGLTCILIVCLIIWGSFSLFNGKIPVKTLFSLSRETGMVTLHGSGNKVLFSHPFIEFDCYLTTTPTPQGFFDYQLFLVHRYNGYKHGVPIGRFINGSKQLDEYKRLWNMIQAYMDVSQPLPDIPMNEPFRDKDSATIAYDKAHNRKPDFWFSMSDEEFEQAVAKIVEKQNTEPPLGEMIPIFATDTEISQEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2I4</accession>
    <name>D0Z2I4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted sialic acid transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_000635</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304930.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000635"/>
    <dbReference type="EnsemblBacteria" id="EEZ39615">
        <property type="protein sequence ID" value="EEZ39615"/>
        <property type="gene ID" value="VDA_000635"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0591">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
        <property type="entry name" value="SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00813">
        <property type="entry name" value="sss"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="45"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="74"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="117"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="154"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="185"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="227"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="272"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="317"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="376"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="401"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="431"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="468"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ39615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="511" mass="54416" checksum="48FDC8D97864C7F3" modified="2010-01-19" version="1">MEWSAVNWFVIALYFAGMLGIGVYFSKRNKSTDDYFKAGGRVPTWVTACSVYATALSSISFIAIPASIYANGAIMGLAPLGIMVMVVWAALVFVPFFRKVNVTTAYEYLGKRFDPKLCYVASISFIVFHIIRIAVVLYLPTLALQQALPGVDPVILVGSVALMCVIYTSIGGIEAVVWSDAIQTIILLAGAVVIAVIGYSASPDGLFAAFDRLVADQKTLPESAFNISFAGTTLIGIILGGVINSIYSYVGSQDIVQRYNITKTTKEAQNSLFMNVPLLFTSMAIFIGMGTALYIFFAFTAPLPGEINGNAILPYFVIKYVPAGLSGLIIAAIFAAAQSTVSSSLNAISTCVTSDLVSKARPDMDDSSKLKVAKGASWIIGLISTALALHFLKAGQGDMFLYFQAITGLLGGPIAGLFLAGIFIKRINAKSAWFGFGISVIVATYIGDPAGLLSGYIPGYVKPQIFEFMISLVVILACVVPAYISSFFFVTSNEESARAEGLTYATATGSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2J7</accession>
    <name>D0Z2J7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DctA-YdbH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000648</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304958.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000648"/>
    <dbReference type="EnsemblBacteria" id="EEZ39628">
        <property type="protein sequence ID" value="EEZ39628"/>
        <property type="gene ID" value="VDA_000648"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2911">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="234208at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021730">
        <property type="entry name" value="DctA-YdbH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11739">
        <property type="entry name" value="DctA-YdbH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="domain" description="DctA-YdbH" evidence="3">
        <location>
            <begin position="880"/>
            <end position="1076"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF11739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="1092" mass="124108" checksum="58907C40643719B0" modified="2010-01-19" version="1">MTLDSYPKKIPASSNSSPDQATNHTSNHKKKWLRRLGFLLAALLGLSLISAYTLLKLLAQHEVQIHRISGIQLFSAPHIEKLAVVYQGVPIEMNHISINTSPLTIKIQQVQSQIPKKDQEPLQPYQFSSLQLEQLEMHSPSWRLDQMFTAKINKATVGLTINQEPTHIYQQQIHQLHIEVDPNNDGDSTNNYSNNSYAIAAKIHDIDVTVPVQTKVEDQPDVEIIQYRANLKQLSAKLQIAKNNPMQHPIPLSVAIDAIKPSWQSLEEIEQTIQNIHIDTDLTHWKSNTTIKINQAHLIQPQYLPLDIKKSDSEYQGFHIGQAIANLAQLPVNFSINQLTYLPLIYNAEVFLQQPSLDNLVTDQEQPQRPHFYFSGHVLSQQPYKMDLSLFYQDLKNMTVTAGLVGKKGNSVFCDSVISADLPLPKRLDCQLNLKQTKDITDNWQMTDAPNAILNKPITLQARQINHLIPNEVKNDDIKSAHYHVDLTLPQKINIQLPEAWSWDLLNIPRQVQVTNDGKLSIELRYAEKFLQLSLRGKQESLGVSVQNKKQHIIKTNLDINKLKCFPTKLQCHGNGVISNHLSSLIFSSLPQQIDTSSPLILQTKSHWQLTYKDQQFIGQLTDNQLSLPSFRLQQPSYSLELSNNQLAVPQWVILANTHQWQWYAPKDKDITFTSNAEATVTIETNSQASHPVQKITSPLKMTMGSFWVDKQSKQSIKIKSHIHSQLSPILNGQTLPKLDLNTQLQLAKGEISLENRIHSLLPNQQSVPLADIKIRHNINQYSGLLDVRLSPWQFDSKRRLSQYYLPEIPTGIELVSGKLEGHLVTRYRQFQPISSQVSLYTKELSGMFFNIPFHNANIQLELQQDQQGIQTRSPAIVDIEKIKLGIPLTNIRLSGHYQDYAYKLNHGYIELLDGFITTTPTQSRQPWQQLSLPISIHGINLAALMSQIDQQDIELTGILDGKLTLALHKGLFDIHNGKLIARYPGGLFRYKQGSTIDNQVEAMDDNNPIVVSKLLKNYHYRTLVVDIDYSNKGILKAKSQFKGYNPDFQNGRPIHLNLNIEDNVPALIKTLSLLNSSDVERYLQEQFGKQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-02-10" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2N2</accession>
    <name>D0Z2N2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Arginine/ornithine antiporter ArcD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_000683</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305050.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39663">
        <property type="protein sequence ID" value="EEZ39663"/>
        <property type="gene ID" value="VDA_000683"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1288">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="350103at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018385">
        <property type="entry name" value="C4_dicarb_anaerob_car-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018387">
        <property type="entry name" value="YcgA/YfcC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43652:SF6">
        <property type="entry name" value="PTHR43652:SF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03606">
        <property type="entry name" value="DcuC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="121"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="160"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="185"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="217"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="241"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="304"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="326"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="359"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="414"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="454"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="485"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="510" mass="55608" checksum="42E6BF2F4AC2E551" modified="2010-01-19" version="1">MNKIFGFFKSMTFPSAFTILFSITIIAVAFTWIIPAGSYSKLLYNTSDKMLQITSPVGEVTQVNATQTELDRLNIKINIDQFTSGVIRKPIAIPDTYEEVAPIHKGMMDVTQSMVEGTIEAADIMVFILILGGMIGIVNKTGSFNSGLIALSHKTKGHEFLLVFSVSLVMALGGTTCGLEEEAVAFYPILVPIFLSLGYDSIICVGAIFLAGSMGSTFSTINPFSVVIASNAAGIPFTEGIVFRTLGLIIAFSVVISYLYWYAKKVKQTPSFSYTYSDHEAFEKRFLEDVNLDAPAPFNIRKKLILTLFVAAFPLMIWGVSVGGWWFPSMAASFLTITIVIMFISGLKEKELIDSFIKGASELVGVSLIIGLARGVNIVLDQGMISDTILFYASNIVSGMEGSIFIISMMFVFFLLGFIVPSSSGLAVLSMPIMAPLADTVGIPRDIVVSAYNWGQYAMLYLAPTGLILATLQMLDMSYNKWLKFVWPMVLFVLSFGAILLVIQVKLSGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2R8</accession>
    <name>D0Z2R8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000719</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305149.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39699">
        <property type="protein sequence ID" value="EEZ39699"/>
        <property type="gene ID" value="VDA_000719"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5030B5Q">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1928770at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="38"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="221" mass="25296" checksum="7AF5AF0A96B8509B" modified="2010-01-19" version="1">MKDSLKNWMLPLLVGVLLGSGSASGYFLYQQQGHDAHSQKLEQQIQLEQQKQLQQQQEFTEDLANKTSQFEQLVAKLNDELKEQKESSDRELAKLQQKITSLQQSTQKLTVTKKKLDTRVVQLKTETKQQQHVISNSQALFTEKANLQGELTQIKSQITQLKGPLAKQKKACDEFKSGTSWNWVSQADCDKYNTMNKEVVALEQKSTLISNRLEQLEKLTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2S3</accession>
    <name>D0Z2S3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptidoglycan D,D-transpeptidase MrdA</fullName>
            <ecNumber evidence="3">3.4.16.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Penicillin-binding protein 2</fullName>
            <shortName evidence="3">PBP-2</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">mrdA</name>
        <name evidence="6" type="ORF">VDA_000724</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes cross-linking of the peptidoglycan cell wall.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell inner membrane</location>
            <topology evidence="3">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the transpeptidase family. MrdA subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.4" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305166.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000724"/>
    <dbReference type="EnsemblBacteria" id="EEZ39704">
        <property type="protein sequence ID" value="EEZ39704"/>
        <property type="gene ID" value="VDA_000724"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0768">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="423699at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008658">
        <property type="term" value="F:penicillin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009002">
        <property type="term" value="F:serine-type D-Ala-D-Ala carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02081">
        <property type="entry name" value="MrdA_transpept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005311">
        <property type="entry name" value="PBP_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036138">
        <property type="entry name" value="PBP_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001460">
        <property type="entry name" value="PCN-bd_Tpept"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017790">
        <property type="entry name" value="Penicillin-binding_protein_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03717">
        <property type="entry name" value="PBP_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00905">
        <property type="entry name" value="Transpeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56519">
        <property type="entry name" value="SSF56519"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03423">
        <property type="entry name" value="pbp2_mrdA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0133">Cell shape</keyword>
    <keyword evidence="3" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="23"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="domain" description="PBP_dimer" evidence="5">
        <location>
            <begin position="67"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="Transpeptidase" evidence="4">
        <location>
            <begin position="287"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="3">
        <location>
            <position position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ39704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="652" mass="73090" checksum="84C1693B5C560AC7" modified="2010-01-19" version="1">MKKTTRTPFRDHTAEVRLFGRRAIFSFAAIIILMGVLIGNLYHLQVQDYSAYKARSNDNRIKIIPVAPNRGRIFDRNGVLLAENVPIYSLDLYPSKMKDLKQTLAGLQKLLGITDEQIAAFYKEKRHTSHYKPVTLIEQMTETQVAEFSVNEFHYPGVDVDAYLERYYPYGAQLTHVLGYVAKINDRDIQRLKDEGVYSNYKATHTIGKLGVERYYESLLHGKSGYEKVEVDSRGRVVRTLSYVPPVSGKDIMLNIDLGLQEYANQLLTQQVKDPVTGKMVTKPRRGSIVVLDPKDNSVLAMASSPSYDPNLFVHGISSKNYRALLNNPDHPLLNRATLGVYPPGSTVKPEIAVAALTTGVITPQTTYDFPGWWQIPNAKTTRKFRDDVRWGHGRVNIYKAIEESVDTFFYQVAYDMGIDRLSTWMKKFGYGQPTGIDIREETNGNMPTREWKHARFKVPWYQGDTIPVGIGQGYWTATPMQIAKAASVIAESGVEHRPHLLKGIVEENDKVDDAEFPDFPKVAAPKQNWQIAQEGMHLVTVSGTARSIFKNVAYPVAGKTGTSQVFTLADNQNYNAKDIAEHLRDHALFVGFAPVQNPKVLVATVLENGGWGKNAAPLAKKIMDYVLLKPTLNPASSENTANDKSMKTTTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2T7</accession>
    <name>D0Z2T7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000738</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305210.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000738"/>
    <dbReference type="EnsemblBacteria" id="EEZ39718">
        <property type="protein sequence ID" value="EEZ39718"/>
        <property type="gene ID" value="VDA_000738"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1555">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1948240at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004509">
        <property type="entry name" value="Competence_ComEA_HhH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003583">
        <property type="entry name" value="Hlx-hairpin-Hlx_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="SMART" id="SM00278">
        <property type="entry name" value="HhH1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00426">
        <property type="entry name" value="TIGR00426"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018857" evidence="1">
        <location>
            <begin position="20"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="HhH1" evidence="2">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="HhH1" evidence="2">
        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="161" mass="17119" checksum="B1AA5955424F29A2" modified="2010-01-19" version="1">MFRALLLSLMLVAPFASQAATPSSSDVKAAIKQCETKYKADAKKKSDCITKAKKSVSKVATKSTKDIKKDVKKTSHKATTSTTKDVKKTKAAVKKNLKAVNVNNASASDLAASLPGIGDAKAKAIVDYRKKHGKFKSAKDLEKVPGLGAKSVGAMSKYLKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2T8</accession>
    <name>D0Z2T8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Inner membrane protein YccF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000739</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39719">
        <property type="protein sequence ID" value="EEZ39719"/>
        <property type="gene ID" value="VDA_000739"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031308">
        <property type="entry name" value="UCP028777"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005185">
        <property type="entry name" value="YccF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03733">
        <property type="entry name" value="YccF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028777">
        <property type="entry name" value="UCP028777"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="YccF" evidence="2">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="YccF" evidence="2">
        <location>
            <begin position="60"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR028777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="135" mass="14539" checksum="0D2B6B8B44F9B9EA" modified="2010-01-19" version="1">MGLAWWFFGLLAFISIVGIPWGRACFVMGTFSFFPFGKDAISRDELTNQDDIGTSGFGIIGNIIWFCLAGIWLAIGHLISAAACFVTIIGIPFALQHLKLAAISLAPIGKTVVDSEVAAAARISNAQDRVNKYRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2V2</accession>
    <name>D0Z2V2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000753</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000753"/>
    <dbReference type="EnsemblBacteria" id="EEZ39733">
        <property type="protein sequence ID" value="EEZ39733"/>
        <property type="gene ID" value="VDA_000753"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="59" mass="6798" checksum="2AF401E6EC3845E9" modified="2010-01-19" version="1">MLENMNLSIPEDIKKEPELPIPTLEEQKKIVAELKRLEEAGELTPEILHAFMTGERKPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2W1</accession>
    <name>D0Z2W1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000762</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000762"/>
    <dbReference type="EnsemblBacteria" id="EEZ39742">
        <property type="protein sequence ID" value="EEZ39742"/>
        <property type="gene ID" value="VDA_000762"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2035">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007163">
        <property type="entry name" value="DUF368"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37308">
        <property type="entry name" value="PTHR37308"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04018">
        <property type="entry name" value="DUF368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="181"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="212"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="267"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="293" mass="31819" checksum="BDD85391C547D591" modified="2010-01-19" version="1">MGAADVVPGVSGGTIAFITGIYDTLLESIRRINPKLISVLKEKGLKGAFEHVNGAFLIALFAGILTSIFTLARFITWMLHTHPIPLWSFFFGLIIVSVIHMFKQVDRWALTRFIAVILGAAFAYGITVVNPVSMDPTPVNIVIAGAIAICAMILPGISGSFILLLLGMYAPILGAAKSMDVVTLGLFAMGCVVGLLTFSHVLSWILRNYRDIALTFLTGLMIGTLGKIWPWKETLTWRINSHGEQVPLVEQNLSPFNFEHVTGQPALLGYAVVAMILGIAIVWGLEKFAQHGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z354</accession>
    <name>D0Z354_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ABC_trans_aux domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000855</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000855"/>
    <dbReference type="EnsemblBacteria" id="EEZ39835">
        <property type="protein sequence ID" value="EEZ39835"/>
        <property type="gene ID" value="VDA_000855"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3009">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005586">
        <property type="entry name" value="ABC_trans_aux"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03886">
        <property type="entry name" value="ABC_trans_aux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC_trans_aux" evidence="1">
        <location>
            <begin position="2"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="137" mass="15213" checksum="3A169649F2D1E72C" modified="2010-01-19" version="1">MASHLNGSGLVYQVSDTKVVEAQNNLWAEAINKQLTRRITDDLRNKQNKFWPTQLTPTLDIAGATRLQVRIDQFNGTYNGIADVAGEWMVMNANGELESVHPFEFKVPLAEPGYNAQVLALSKGVDELTSQIAQQIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z395</accession>
    <name>D0Z395_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000896</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000896"/>
    <dbReference type="EnsemblBacteria" id="EEZ39876">
        <property type="protein sequence ID" value="EEZ39876"/>
        <property type="gene ID" value="VDA_000896"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502Z8RZ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="165"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="193"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="227"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="262"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="286"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="311"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="342" mass="39715" checksum="2E941474F1DF8A38" modified="2010-01-19" version="1">MKITKRQAQFLDQTLSHWHKKGLIDDEQAKQLAVSYEIIGFDWKLLAVYSFWIAISCFVISVSVLVADDYLMSLIAKIIDTPASILALLSALIATMFYGFGIRRRRLNPSKNISNEAIFFFGVLMTAVSFGFLHETSTFNQWSDTWFILAPTLIYGFLGFQLRSILIWLFFLIGAGLWYLLQTDLWSSSEHYFLGTNIPLRFVFFGAVILAFGHWQKERQPYLQDSTLFMGLLYSFFALWLLSIFGNYSEINLWQKTPQIELIQWAAFSIFGCLGAIYFGIKHNQVLYRSFGITFLLINLYTRFFEYFWDSMHKTIFFALLAISFWALGSKAEKLYPSDINK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3G9</accession>
    <name>D0Z3G9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glutaredoxin 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000970</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000970"/>
    <dbReference type="EnsemblBacteria" id="EEZ39950">
        <property type="protein sequence ID" value="EEZ39950"/>
        <property type="gene ID" value="VDA_000970"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2999">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007494">
        <property type="entry name" value="Glutaredoxin2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04399">
        <property type="entry name" value="Glutaredoxin2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="SSF47616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutaredoxin2_C" evidence="1">
        <location>
            <begin position="2"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="43" mass="4959" checksum="A7FBE465147C9683" modified="2010-01-19" version="1">MVDEAILFSILRGFFSATEIQWDNAVKDWMESVSNKTQVPLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3K3</accession>
    <name>D0Z3K3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">6-carboxy-5,6,7,8-tetrahydropterin synthase</fullName>
            <ecNumber evidence="5">4.1.2.50</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Queuosine biosynthesis protein QueD</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">VDA_001004</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>7,8-dihydroneopterin 3'-triphosphate + H2O = 6-carboxy-5,6,7,8-tetrahydropterin + acetaldehyde + 2 H(+) + triphosphate</text>
            <dbReference type="Rhea" id="RHEA:27966"/>
            <dbReference type="ChEBI" id="CHEBI:15343"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18036"/>
            <dbReference type="ChEBI" id="CHEBI:58462"/>
            <dbReference type="ChEBI" id="CHEBI:61032"/>
            <dbReference type="EC" id="4.1.2.50"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Purine metabolism; 7-cyano-7-deazaguanine biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PTPS family. QueD subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.50" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305961.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001004"/>
    <dbReference type="EnsemblBacteria" id="EEZ39984">
        <property type="protein sequence ID" value="EEZ39984"/>
        <property type="gene ID" value="VDA_001004"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0720">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="993025at2"/>
    <dbReference type="UniPathway" id="UPA00391"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070497">
        <property type="term" value="F:6-carboxy-5,6,7,8-tetrahydropterin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007115">
        <property type="entry name" value="6-PTP_synth/QueD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038418">
        <property type="entry name" value="6-PTP_synth/QueD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01242">
        <property type="entry name" value="PTPS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ39984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="292" mass="32971" checksum="6F27F8D907748DA1" modified="2010-01-19" version="1">MKLFVRDLTVIDASYLSVERGMVGESWILDVVMSGELNEMSMVLDFSRVKKQIKQLVDQFVDHRLIVPTQNSAIKAQQVEDGYFTVDLLRGDNSIYLKSPEQAFCFIDAQEVTIETVTKHLHNVLSGHMPANVEGLELTLRHEKIDGAFYHYSHGLKKHDGNCQRIAHGHRSPIELLVNGKRHSVLEQEWAERWQDIYLAAEEDVVELSLLDLSENAQNLSSEQYVGFSYQAPQGKFDLAIAKNKTEILPTDTTVELLAYYIAQQVKPKLETNDSLDVFAYEGVGKGAMASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3L9</accession>
    <name>D0Z3L9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306000.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001020"/>
    <dbReference type="EnsemblBacteria" id="EEZ40000">
        <property type="protein sequence ID" value="EEZ40000"/>
        <property type="gene ID" value="VDA_001020"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0110">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1878940at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14602">
        <property type="entry name" value="Hexapep_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="227" mass="25367" checksum="B4EE8A6079A785B9" modified="2010-01-19" version="1">MWTYRVRSYIKQRNSLFSRCLYSVVITIRDGQLPRMVWVYRPIYLLYQLIKQVWARLVNVIFYLPMLQARLTQFAPRLQLENGFPLIGGPVEITIGQNTCLNGALSIHAHPDTPSRLIIGDNCYLGWQTSIIVGLSVTIGNNVKIAGRTSIHSHAGHSTDSSHRDKTPELGHLTIEDDVWICTSCNIVKPVLIGRGSVIASGCVVTHDVPPNVLFAGNPGRVIRQLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3N1</accession>
    <name>D0Z3N1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 14">Transketolase</fullName>
            <ecNumber evidence="8 14">2.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">VDA_001032</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 14">Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = aldehydo-D-ribose 5-phosphate + D-xylulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:10508"/>
            <dbReference type="ChEBI" id="CHEBI:57483"/>
            <dbReference type="ChEBI" id="CHEBI:57737"/>
            <dbReference type="ChEBI" id="CHEBI:58273"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="2.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="14">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <cofactor evidence="14">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="14">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <text evidence="14">Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
        <text evidence="14">Binds 1 thiamine pyrophosphate per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7 14">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 14">Belongs to the transketolase family.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.1" evidence="8 14"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306034.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001032"/>
    <dbReference type="EnsemblBacteria" id="EEZ40012">
        <property type="protein sequence ID" value="EEZ40012"/>
        <property type="gene ID" value="VDA_001032"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0021">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="188169at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004802">
        <property type="term" value="F:transketolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02012">
        <property type="entry name" value="TPP_TK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005478">
        <property type="entry name" value="Transketolase_bac-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020826">
        <property type="entry name" value="Transketolase_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033247">
        <property type="entry name" value="Transketolase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005474">
        <property type="entry name" value="Transketolase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43522">
        <property type="entry name" value="PTHR43522"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00456">
        <property type="entry name" value="Transketolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00232">
        <property type="entry name" value="tktlase_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00801">
        <property type="entry name" value="TRANSKETOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00802">
        <property type="entry name" value="TRANSKETOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 14" id="KW-0106">Calcium</keyword>
    <keyword evidence="12 14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="15" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13 14" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="9 14 17" id="KW-0808">Transferase</keyword>
    <keyword evidence="15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="416"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="domain" description="TRANSKETOLASE_1" evidence="16">
        <location>
            <begin position="11"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00002931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00007131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00013152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU004996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS00801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EEZ40012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="664" mass="72150" checksum="CA7826D59E95A403" modified="2010-01-19" version="1">MDRKHLANAIRALSMDGVQQANSGHPGAPMGMADIAEVLWRSHMNHNPQNPNWADRDRFVLSNGHGSMLIYSLLHLTGYDLSIDDLKNFRQLHSKTPGHPEYGYAPGVETTTGPLGQGITNAVGMALAEKALAAQFNREGHDIVDHHTYAFMGDGCMMEGISHEACSLAGTLGLGKLIAFWDDNGISIDGHVEGWFSDDTPKRFEAYGWQVIRSVDGHDAAAINAAIEEAKADTTRPTLICCKTIIGFGSPNKSGSHDCHGAPLGAEEIKAAREFLGWNYGAFEIPTDVYAEWDAKAAGTAKETAWDEKFAAYAAQYPELAAEFKRRVNGELPANWEEASSAIIADLQANPANIASRKASQNALEAFGKLLPEFMGGSADLAPSNLTMWSGSKSLTADDTSGNYIHYGVREFGMTAIINGIALHGGFVPYGATFLMFMEYARNAMRMAALMKVQNIQVYTHDSIGLGEDGPTHQPVEQVASLRLTPNMSTWRPCDQVESAVAWKFAIERKDGPTSLIFSRQNLAQQERDAQQLADITKGGYVLKDCDGKPELILIATGSEVELATEAYALLTAEGRKVRVVSMPATDVFDKQDAVYRESVLPSDVTARVAIEAGIADFWYKYVGFDGRIIGMTSFGESAPADQLFKLFGFTVENVVETAKELLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3S1</accession>
    <name>D0Z3S1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Endoxylanase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001072</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306148.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001072"/>
    <dbReference type="EnsemblBacteria" id="EEZ40052">
        <property type="protein sequence ID" value="EEZ40052"/>
        <property type="gene ID" value="VDA_001072"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5032SKS">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="922127at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010502">
        <property type="entry name" value="Carb-bd_dom_fam9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06452">
        <property type="entry name" value="CBM9_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0858">Xylan degradation</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003020060" evidence="1">
        <location>
            <begin position="22"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="Carb-bd_dom_fam9" evidence="2">
        <location>
            <begin position="39"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="239" mass="27141" checksum="F9DD9B5200FB09F4" modified="2010-01-19" version="1">MKLALLTTLAAATLFSAATYASDNNKTYSVNFTDKAPVIDGQLDTNIWDKAENLTDFTFPWRKVVPPKTEFKALWDQDALYFIYTVTDKNVAIGTDPERAILDSDRVEIFLAKDTALSHYYTMEIDPKGRVFSAKASFDMKTQKRASLDSQWRWPGLETKAVLTDMGYQVEGKLPLATLSQLELWQDKSQSELLCALMRAEFTQQDGQLDMGWMTWVDPKTPKPNFHNPQTFGSCKLVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3S6</accession>
    <name>D0Z3S6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PTS system N-acetylgalactosamine-and galactosamine-specific IIA component</fullName>
            <ecNumber evidence="4">2.7.1.69</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001077</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.1.69" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306162.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001077"/>
    <dbReference type="EnsemblBacteria" id="EEZ40057">
        <property type="protein sequence ID" value="EEZ40057"/>
        <property type="gene ID" value="VDA_001077"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2893">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2008912at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103111">
        <property type="term" value="F:D-glucosamine PTS permease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008982">
        <property type="term" value="F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00006">
        <property type="entry name" value="PTS_IIA_man"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.510">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004701">
        <property type="entry name" value="PTS_EIIA_man-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036662">
        <property type="entry name" value="PTS_EIIA_man-typ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033887">
        <property type="entry name" value="PTS_IIA_man"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03610">
        <property type="entry name" value="EIIA-man"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53062">
        <property type="entry name" value="SSF53062"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51096">
        <property type="entry name" value="PTS_EIIA_TYPE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PTS EIIA type-4" evidence="3">
        <location>
            <begin position="1"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="147" mass="15710" checksum="7FEC3A3946FF78D5" modified="2010-01-19" version="1">MIGIVVSGHIHFASGVASAVRAIAGEQEQMCYVDFVETMSTDELELALRQAAQEVDSGDGVLFLTDIPGGSPANRALAILMDTPNVELIGGANLPMIANAAFERDGVELKELVEILLEIGGSCMQDMRKQLEMMMAPEPEVECEDGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3X2</accession>
    <name>D0Z3X2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001125</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306282.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40103">
        <property type="protein sequence ID" value="EEZ40103"/>
        <property type="gene ID" value="VDA_001125"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502ZMQ1">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2071318at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="60" mass="6833" checksum="E09C503E37B0224C" modified="2010-01-19" version="1">MKVVIEFTETGKYRDQAWEGSFLCSKGQLHAVTPSYAAQLIQQRKAVVCMDKDGEIRIEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z419</accession>
    <name>D0Z419_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NADH dehydrogenase subunit N</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000275</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000275"/>
    <dbReference type="EnsemblBacteria" id="EEZ39257">
        <property type="protein sequence ID" value="EEZ39257"/>
        <property type="gene ID" value="VDA_000275"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0651">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042773">
        <property type="term" value="P:ATP synthesis coupled electron transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003918">
        <property type="entry name" value="NADH_UbQ_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001750">
        <property type="entry name" value="ND/Mrp_mem"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00361">
        <property type="entry name" value="Proton_antipo_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01437">
        <property type="entry name" value="NUOXDRDTASE4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="44"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="89"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="130"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="167"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="195"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="237"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="267"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="307"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="353"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="395"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="450"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="549"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="domain" description="Proton_antipo_M" evidence="3">
        <location>
            <begin position="55"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="570" mass="61084" checksum="1B397AF44408BAD0" modified="2010-01-19" version="1">MDMLSALMVCVISIVTIASSIYSINYLQEYLGKGGWKISVLFNLFAAAMTALVVAANVMVFMFFVEIISLASVLLVVSGGSEANRKAGLQYFVVDHLANLFILVAFLILVCHSHSFDFSVFVATPITGTTASWAFIFALFGFGIKAAGIGLHGWMPKIYPLAPSHSSTLISCVMVKLGIYGIIKFGIMFLGASQLWWGIVVLIFGALSSVLGVMYALAEHNIKRLLAYHTVENIGIILIGVGVAMIGIATVHPVIALLGLLGALYHLLNHAVFKGLLCLGSGSIVYRMHTKEMDQMGGLGKTMPKTALAFLIGTMAICALPPLNGFVSEWFIYQSLFSLGKAGSVTNLIFGPFGMVMLALTGALACMCFVKVYGVCFTGAPKSEQAANTKEVGPAMTLATSSLAIVCIILGVGSPWIAPYFSAIASSMLNLMPVPVASGAALYPVIPTQAILSTPVIAIALALLTLVPALLLMIFGGHRVSRRQQGDPWACGYQYEQRMTVSTAGITAPMRQMFGFIYNNRPKTSLTERYVLPFFVDLNGQLSCHKVKVFCVVLALFVIGFFPFISGVSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4F6</accession>
    <name>D0Z4F6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PNPLA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000412</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304297.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39394">
        <property type="protein sequence ID" value="EEZ39394"/>
        <property type="gene ID" value="VDA_000412"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4667">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="373926at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07208">
        <property type="entry name" value="Pat_hypo_Ecoli_yjju_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045943">
        <property type="entry name" value="DUF6363"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037483">
        <property type="entry name" value="YjjU-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19890">
        <property type="entry name" value="DUF6363"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="1 2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="3">
        <location>
            <begin position="6"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="2">
        <location>
            <begin position="38"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DGA/G" evidence="2">
        <location>
            <begin position="159"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="40"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="279" mass="31371" checksum="E2E77990EAFC6966" modified="2010-01-19" version="1">MTKHALVVEGGAMRGIFATGVLDAFLEHDFNPFDFTIGVSAGSVVLMGYLCKDYQRNYKVITEYARSKDFISYKRFVEGGNLIDIDWLWKASVEHLPLGLHEYEKQGVPLFATTTNVVTGDPSYIEVTRENLTEVMTATCALPIVYKNFPQVNGIAMSDGGIADPIPVIEAYNKGAREITVVLSHPQALFAHNRQVPWLTRRIFKTQPVFAQEFLTKESRYNKALYFIKNPPADCKINAIIPDKNFQIKRLTKNLDKLDAGYQQGRNAGLSLVKSYSNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4L8</accession>
    <name>D0Z4L8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Histidine kinase</fullName>
            <ecNumber evidence="3">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_000476</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304469.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000476"/>
    <dbReference type="EnsemblBacteria" id="EEZ39456">
        <property type="protein sequence ID" value="EEZ39456"/>
        <property type="gene ID" value="VDA_000476"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1293707at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038318">
        <property type="entry name" value="KdpD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025201">
        <property type="entry name" value="KdpD_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13493">
        <property type="entry name" value="DUF4118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="58"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="6">
        <location>
            <begin position="268"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="488" mass="54553" checksum="240ED6FEEFCD11F2" modified="2010-01-19" version="1">MNNQFTWADGKKILCLFTLYALVTYVGVRFRDVIIETDTAMLLLLLNIVSGFWLRKRMAYVITAMSIVAFHFFVLPEHNSFKFQNYQHIITFAVMAFSGVFAVKITQSQQRELHKNIALRSELKSNYGLASVLASLNESVEIAEASIQHLASCRQIKAQVWLFQPNLYCLASHENLEQTHFIEQVEAYYQKGCDDIQSVSAHVELHPLYSQNGVFGVLVVEFYQPTTFNPILSTLISLSLARSEANHALAMVKEANQMEQMRNTLLAAVSHDLKTPLGSIIGSATTLNDPNIHLPPQTKQELLQSIAEEGYSLNRSLTKLLDISRYSIKTLVPKCDWVEPEEVIGSAIKRVELLLKQHPISLVGDTMLVSLDYTLIEQVIANLIENAAKYSSGNSPIDISTCYLDGAFVFSIADRGCGVAPEDTQRIFERFYRSEHVKVKGTGLGLAICKLIVSAHKGTISVASREGGGSIFTVQIPCERYELTDIYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4Y7</accession>
    <name>D0Z4Y7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306642.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000220"/>
    <dbReference type="EnsemblBacteria" id="EEZ39204">
        <property type="protein sequence ID" value="EEZ39204"/>
        <property type="gene ID" value="VDA_000220"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3316">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1667004at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032874">
        <property type="entry name" value="DDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13610">
        <property type="entry name" value="DDE_Tnp_IS240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_IS240" evidence="1">
        <location>
            <begin position="70"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="228" mass="26760" checksum="26E88020A2302684" modified="2010-01-19" version="1">MPFTGYHFPSNIILQAVRNYVAYKLSYRDIEEIFAERGIRVDHATINRWVIRFAPLIEQNARVRKRQVSSSWRMDETYIKIKGKRWYYYRAVDKYGDIVDFYLSQTRDEKAAKVFLRKAIRTNGLPDKVIIDKSGANAQALHNMNIQLWKSVVFMLNLIEVIDVKYLNNIVEQSHRPIKQKMRQALGWKSVEGAQATMSGQEVWTQLKRGQVGDLSLPVWERFYALVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-02-10" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z502</accession>
    <name>D0Z502_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase OrfAB subunit B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000235</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39219">
        <property type="protein sequence ID" value="EEZ39219"/>
        <property type="gene ID" value="VDA_000235"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2801">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13333">
        <property type="entry name" value="rve_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="1">
        <location>
            <begin position="52"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="225" mass="26496" checksum="A07BA57DF7E34B2B" modified="2010-01-19" version="1">MVTTQGIPLSRYRASKQMKALNLVSCQSPKHRYRKVNQEHITIPNHLDRQFTVTAPNQIWVGDVTYVWAGHRWMYLAVVIDLFSRKPVGWAMSLSPDSRLTGKALMMAYESRQKPKEVMFHSDQGSHYTSRYYRQLLWRCQIKQILSRRGNCWDNAPMEHFFRSLKTEWVPNVGYRSFAEAKHEITRYIIGYYSQLRPHQYNGGLTPNESERLYWLTSKTVASIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z522</accession>
    <name>D0Z522_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Extensin-like protein:NEAr transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000255</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306748.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39239">
        <property type="protein sequence ID" value="EEZ39239"/>
        <property type="gene ID" value="VDA_000255"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031P3K">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="552" mass="62507" checksum="7EE188C7F40DDBE5" modified="2010-01-19" version="1">MRNIVVLLSLLSLAGCGDGGSDSDKSKISEMAKPEIVKPEVVKPEVVKPEVVKPEVVKPEVVKPEVVKPEVVKPEVVKPEVVKPEVVKPEVVKPEVVKPEVVKPEVVKPEVVKPADPKDMALTFFNVDMYQNGSANIKYIEMNAGNQPYELNIHELNERSMYGNKITHKLNYKDINGNLHSENYLIDVNNKLIIKTDNSILYKDGTYKTFNYSDKYINFDFNLEKGQENNKVFNVTTFDSDLHHIVTIPIKVTTKYIGLDKIEVGDIFYNTGKFETIEDTKHSKTIITTWFNITNGAIVKQTKIINDINNTTIKNTLNIVDSSINFNYFYNKNAFDKFNLDFMNSNQVSENNINLYIGKDNPVIISLINNNIKISSYNDIDFENASVVSKTIESHSDGGVLSSFISKIQYSRVECEVNCSRPMINTLYLLGVRNNFDNSKNYDSEYAGVYNWYRTDDGFISDNYYIVMDLKAKTCQISSRVKLNAYKCVNLDIDIDSGQIVAVVVNKNTGTYGSLFANINGKNNEYITGVVRDKNINDKSIDTFIIKKDNYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5F5</accession>
    <name>D0Z5F5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA topoisomerase</fullName>
            <ecNumber evidence="3">5.6.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Omega-protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Relaxing enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Swivelase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Untwisting enzyme</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">VDA_000062</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP-independent breakage of single-stranded DNA, followed by passage and rejoining.</text>
            <dbReference type="EC" id="5.6.2.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the type IA topoisomerase family.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.1" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000006">
        <property type="protein sequence ID" value="EEZ39007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005307127.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000006.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000062"/>
    <dbReference type="EnsemblBacteria" id="EEZ39007">
        <property type="protein sequence ID" value="EEZ39007"/>
        <property type="gene ID" value="VDA_000062"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0550">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="100725at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003917">
        <property type="term" value="F:DNA topoisomerase type I (single strand cut, ATP-independent) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03362">
        <property type="entry name" value="TOPRIM_TopoIA_TopoIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000380">
        <property type="entry name" value="Topo_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003601">
        <property type="entry name" value="Topo_IA_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023406">
        <property type="entry name" value="Topo_IA_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013497">
        <property type="entry name" value="Topo_IA_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013824">
        <property type="entry name" value="Topo_IA_cen_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013825">
        <property type="entry name" value="Topo_IA_cen_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013826">
        <property type="entry name" value="Topo_IA_cen_sub3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023405">
        <property type="entry name" value="Topo_IA_core_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003602">
        <property type="entry name" value="Topo_IA_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013498">
        <property type="entry name" value="Topo_IA_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034144">
        <property type="entry name" value="TOPRIM_TopoIII"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11390">
        <property type="entry name" value="PTHR11390"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01131">
        <property type="entry name" value="Topoisom_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01751">
        <property type="entry name" value="Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01396">
        <property type="entry name" value="zf-C4_Topoisom"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00417">
        <property type="entry name" value="PRTPISMRASEI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00437">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00436">
        <property type="entry name" value="TOP1Bc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56712">
        <property type="entry name" value="SSF56712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00396">
        <property type="entry name" value="TOPOISOMERASE_I_PROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9 15" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0799">Topoisomerase</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Toprim" evidence="14">
        <location>
            <begin position="1"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00032877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEZ39007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="727" mass="82046" checksum="FB0251FF188A92F1" modified="2010-01-19" version="1">MRLFIAEKPSLAKAIFEGLGGNPKTQRKQGYFENGNDIVTWCVGHLLEQSPPEHQWKLEYLPIKSEYPPKMRPIEKTKDQFKVVQDLIKKADSIVNASDPDEEGNLLCDEILTYCHNTKPVERLLVADLNLEPVKRALANMQPNENFHGWTQSALARSIGDLIFGFNMSQAYTLKAREMGYSGTFGIGRVQTVALGMINERTLANQSHQESYFYQVYADFAFNNQTVKARYLPTTNNEVDEQNRLLSKTEAKQIAQATDNQHALIIDAQTKPTKSLPPRPYDLSSLQQLCAKKWGYSAKKTLDICQSLYEKHKVLTYPRTDNRFLGDSHLEQRVAIFKNIAEAIPELSSMVANADLSLKHHAFDASKITAHHAIVPTLTSAKGLTLTKDEQTIYEFVARSFIALFYPASVRDRTEVTIELANKYRFKANQTQLSVVGWEVLYKDDIEAEKPIEGVDLTTLKRDQETKASNPTIEKGKTKPPKYHDEASLIAFMKKAGKLIKDPELRAKFEAKDKGDRDNCGSIGTEATRANILDTVKSRSDLVQVVKMKGYKQKVWITTPLGQEFCAMLPSEFTAPDISAIWSQHQLAIKNGDMTVEQFLDELDGFVAHYVDKVKTNGVNITVETFDCPNCADGHLIKRNGSKGVFWSCNRYPECKTSFPDKSGKPDTAPKAKPQVSEFNCPLCQKPLVRRKGKSDKDKPEKYFYGCSGYPQCKASYQEQDNKPKFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVI6</accession>
    <name>D0YVI6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lysophospholipid transporter LplT/2-acylglycerophosphoethanolamine acyltransferase/acyl-[acyl-carrier-protein] synthetase</fullName>
            <ecNumber evidence="3">2.3.1.40</ecNumber>
            <ecNumber evidence="3">6.2.1.20</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001566</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.3.1.40" evidence="3"/>
    <dbReference type="EC" id="6.2.1.20" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298291.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001566"/>
    <dbReference type="EnsemblBacteria" id="EEZ40540">
        <property type="protein sequence ID" value="EEZ40540"/>
        <property type="gene ID" value="VDA_001566"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0204">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="961884at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008779">
        <property type="term" value="F:acyl-[acyl-carrier-protein]-phospholipid O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008922">
        <property type="term" value="F:long-chain fatty acid [acyl-carrier-protein] ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="176"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="231"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="264"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="297"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="335"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="378"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="404"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="domain" description="PlsC" evidence="2">
        <location>
            <begin position="457"/>
            <end position="571"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="625" mass="69552" checksum="4A53F5D95BC91315" modified="2010-01-19" version="1">MALSPHSSLLRKQRFLPYFLTQALGAFNDNVYKNVLLILIAFAAPGALPFSSDLAINIAAGLFILPFFLFSASAGVLSDIYDKAQIMRIVKFAEIIIMACAAIAFITQSYLILLFLLFLMGTQSAFFGPAKYALLPQHLKKEELIAGNALVEMGTFLAILLGTLFAGVIADSSQHAHLFAGISVVTFAILGYLTSRKIPEAKPSLHGVQFQWRPIEQTKTTLAIAKKDKTIFQCVMGISWFWFLGACYLTQFPNFTRESLGGSAASVSLLLALFSIGIAIGSMLCNKLSHQRVEPGIVTLGCIGMTLFGADLYFATPNIAPVTQSVFDFLTQPELIRVFVSLVMLGVSGGLFIVPLYALMQERSPEDERAQIVAANNIWNAIFMVFSSLAAIIFISVLKLSIPEFFLVLAIMNALVVIYIYRQAPDFFWRFIVWLVSHTMYRVRHKNVKNIPQQGAALLVCNHVTYMDALLLAGACPRPIRFLMDIRLYKLPMINAFCRACKVIPVDSQDRRSIQKAFNQIDTLLKAGDIVCLFPEGQLTYDGEIGPFMRGVEVITKRNKVPIIPMALQGLWGSFFSRERGRAVLKRPKRFWSKINIIVGDPIYPPEVSKEELRAQVIELRGSER</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVK2</accession>
    <name>D0YVK2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glucose-6-phosphate 1-epimerase</fullName>
            <ecNumber evidence="3">5.1.3.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001582</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>alpha-D-glucose 6-phosphate = beta-D-glucose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:16249"/>
            <dbReference type="ChEBI" id="CHEBI:58225"/>
            <dbReference type="ChEBI" id="CHEBI:58247"/>
            <dbReference type="EC" id="5.1.3.15"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glucose-6-phosphate 1-epimerase family.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.15" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001582"/>
    <dbReference type="EnsemblBacteria" id="EEZ40556">
        <property type="protein sequence ID" value="EEZ40556"/>
        <property type="gene ID" value="VDA_001582"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0676">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047938">
        <property type="term" value="F:glucose-6-phosphate 1-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09020">
        <property type="entry name" value="D-hex-6-P-epi_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008183">
        <property type="entry name" value="Aldose_1/G6P_1-epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025532">
        <property type="entry name" value="G6P_1-epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01263">
        <property type="entry name" value="Aldose_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016020">
        <property type="entry name" value="PHexose_mutarotase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="SSF74650"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="4">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR016020-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="259" mass="28909" checksum="859DEC86702FB5E7" modified="2010-01-19" version="1">MVEAGISLHGGHLIWFKPAAEKDVIWLSEKAEFDPAKAIRGGIPVCWPWFGKAGTPSHGFARNSQWTLEQHRENDQGVIVSLTLEDNEQTQAIWPHKFHNRLIFEMGSELKVHLTTTNTDNQTWSYGGALHTYFDIANIKQIAITGMGEEYQDSTQGGAICHGESELTFHAETDRVYTQPNNIITIDDKANQRQINVENQGHNAAVIWNPWQELSISMGDMADDSYETMVCVESAIHGQGVTLEPNQAHTLSTIISVVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVL3</accession>
    <name>D0YVL3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 13">Aspartate-semialdehyde dehydrogenase</fullName>
            <shortName evidence="13">ASA dehydrogenase</shortName>
            <shortName evidence="13">ASADH</shortName>
            <ecNumber evidence="8 13">1.2.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Aspartate-beta-semialdehyde dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">asd</name>
        <name evidence="15" type="ORF">VDA_001605</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 13">Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>L-aspartate 4-semialdehyde + NADP(+) + phosphate = 4-phospho-L-aspartate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:24284"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57535"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="1.2.1.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4 13">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 2/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 13">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 2/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5 13">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 2/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7 13">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 13">Belongs to the aspartate-semialdehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.11" evidence="8 13"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001605"/>
    <dbReference type="EnsemblBacteria" id="EEZ40578">
        <property type="protein sequence ID" value="EEZ40578"/>
        <property type="gene ID" value="VDA_001605"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0136">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00016"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00463"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00464"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004073">
        <property type="term" value="F:aspartate-semialdehyde dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071266">
        <property type="term" value="P:'de novo' L-methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019877">
        <property type="term" value="P:diaminopimelate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02121">
        <property type="entry name" value="ASADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000319">
        <property type="entry name" value="Asp-semialdehyde_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011534">
        <property type="entry name" value="Asp_ADH_gamma-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012080">
        <property type="entry name" value="Asp_semialdehyde_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000534">
        <property type="entry name" value="Semialdehyde_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012280">
        <property type="entry name" value="Semialdhyde_DH_dimer_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46278:SF4">
        <property type="entry name" value="PTHR46278:SF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01118">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02774">
        <property type="entry name" value="Semialdhyde_dhC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00859">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01745">
        <property type="entry name" value="asd_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01103">
        <property type="entry name" value="ASD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 13" id="KW-0220">Diaminopimelate biosynthesis</keyword>
    <keyword evidence="11 13" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="12 13" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="13" id="KW-0521">NADP</keyword>
    <keyword evidence="13 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 13" id="KW-0791">Threonine biosynthesis</keyword>
    <feature type="domain" description="Semialdhyde_dh" evidence="14">
        <location>
            <begin position="3"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="13">
        <location>
            <position position="135"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="13">
        <location>
            <position position="275"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="10"/>
            <end position="13"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="37"/>
            <end position="38"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="165"/>
            <end position="166"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="241"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="244"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="268"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="351"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00010584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00013120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEZ40578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="372" mass="40415" checksum="7E65EF566676DD6A" modified="2010-01-19" version="1">MMKVGLVGWRGMVGSVLMQRMVEEGDFAHIEPVFYSTSQVGIPAPNLGKEAGLLQDAFNIDSLKQLDAIITCQGGSYTEKVYPALRQAGWKGYWIDAASTLRMQSDSIISLDPVNFEQIKQGIHSGTNTFVGGNCTVSLMLMAVGGLYQAGLVEWMTSQTYQAASGAGAKNMRELIAQMGVVNDSVLSELANPASSILDIDRKVADTLRSNNFPTQEFGAPLAGSLIPWIDVKRDNGQSKEEWKGSVETNKILGLDSNPIPIDGTCVRIGAMRCHSQALTIKLKQNVPLDEIEQIIASHNDWVKVIPNEREATVQELSPAKVTGTLSVPVGRLRKLAMGDDFLNAFTVGDQLLWGAAEPLRRTLRIILAEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVM7</accession>
    <name>D0YVM7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0352 protein VDA_001596</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001596</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0352 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298347.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001596"/>
    <dbReference type="EnsemblBacteria" id="EEZ40569">
        <property type="protein sequence ID" value="EEZ40569"/>
        <property type="gene ID" value="VDA_001596"/>
    </dbReference>
    <dbReference type="GeneID" id="57342342"/>
    <dbReference type="eggNOG" id="COG3082">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1958957at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00816">
        <property type="entry name" value="UPF0352"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009857">
        <property type="entry name" value="UPF0352"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023202">
        <property type="entry name" value="YejL_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07208">
        <property type="entry name" value="DUF1414"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006188">
        <property type="entry name" value="UCP006188"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158651">
        <property type="entry name" value="SSF158651"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="72" mass="7888" checksum="761B78550AAFB9DB" modified="2010-01-19" version="1">MPITSKYSTKQVEKIIDEVFDVLEKNQVSPELALMIVGDVATNVINSNVPAGQRQAIAEKFALALQSTIKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVR9</accession>
    <name>D0YVR9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily (MFS_1) transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_002010</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002010"/>
    <dbReference type="EnsemblBacteria" id="EEZ40978">
        <property type="protein sequence ID" value="EEZ40978"/>
        <property type="gene ID" value="VDA_002010"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="626204at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="92"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="151"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="183"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="233"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="266"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="298"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="322"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="354"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="381"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="16"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="413" mass="44855" checksum="5C05BE1A8D652719" modified="2010-01-19" version="1">MNSLTQPIEAKFSPFSLFTLYLIIFLGSAGFFITIPAYVSLFLTDHSLAIAQNMPIEQRRELFGTVMSAAPFISMFFTPLLARLADHFGRKIMMAICLLIAGVGFILPVYAIALGSVVLLFAGNMINSLGSASQPMAQAVLSDNSEGKNKAALMSLVAVVMTAAMSFGPALGSKLTAMYGAEGPFYACLFIALICLALLQNVRLPKQHKADSDNPLSFVAPLQRSQSGLIKSLAIVFLGQFSWSLYFQNISFIFPQKWQLEVSGSFYQNYMIAIGIVMIIALLVLPKWILSRWSVTKALRITLLFSALGMATLALTPTPLTHTIAMVVTATFVAISFPLYITSLSNRASDIDQGWAMAMSSAMVGLAWTLTGYLTAVLVNISLMLPTWIAVIGYIAASFLVPKMLNKEMVDAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVS3</accession>
    <name>D0YVS3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_001988</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001988"/>
    <dbReference type="EnsemblBacteria" id="EEZ40956">
        <property type="protein sequence ID" value="EEZ40956"/>
        <property type="gene ID" value="VDA_001988"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1132">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="26"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="59"/>
            <end position="66"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ40956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="281" mass="30586" checksum="96726F1A7E89A436" modified="2010-01-19" version="1">MKTLAKPIEIKDSPNAKPLSVTQGSIRFEDVSFHYGENKGVLSHLNLDIKPGEKVGLVGRSGAGKSTLVNLLLRFHDLEGGKISIDGQDIAKVTQDSLRSNIGMVTQDTSLLHRSIKDNILYGRPDATDDELYAATKQAHADEFISTLTDPFGHCGYDAQVGERGVKLSGGQRQRIAISRVLLKNAPLLILDEATSALDSEVEAAIQESLYELMEGKTVIAIAHRLSTIAAMDRLIVLDKGEIVEHGTHQELLAQHGIYAQLWSHQTGGFIGEQNLTETVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVU5</accession>
    <name>D0YVU5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002026</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299211.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40994">
        <property type="protein sequence ID" value="EEZ40994"/>
        <property type="gene ID" value="VDA_002026"/>
    </dbReference>
    <dbReference type="GeneID" id="57341830"/>
    <dbReference type="eggNOG" id="ENOG5031N7B">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1765149at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="97" mass="11299" checksum="AAC0108E8528166E" modified="2010-01-19" version="1">MSRFECLERIVEEYRKKVRDSEFNRQNDSEVAKVLVLLVGNSMFSLADQFADWVNRGGDRAYGGKFFVSKQLMTLLEPVTFRGVTVRRDSIKLFRIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW09</accession>
    <name>D0YW09_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative outer membrane lipoprotein Pcp</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001314</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40289">
        <property type="protein sequence ID" value="EEZ40289"/>
        <property type="gene ID" value="VDA_001314"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3133">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019867">
        <property type="term" value="C:outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008816">
        <property type="entry name" value="Gly_zipper_2TM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05433">
        <property type="entry name" value="Rick_17kDa_Anti"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rick_17kDa_Anti" evidence="1">
        <location>
            <begin position="31"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="126" mass="12463" checksum="2ED9ED5A5AB6871A" modified="2010-01-19" version="1">MGDARQVQTVLTGTITKLDAVTIQGDAGNTIGTLAGGAIGALLGSEIGGGTGSDIAAIGGGVVGSMVGSKAGQAADTRQGVNIVIKLDSGRTIAVVQQVDPNVIFRVGERVDIYQQGSTTRVVPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW33</accession>
    <name>D0YW33_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001296</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297817.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40271">
        <property type="protein sequence ID" value="EEZ40271"/>
        <property type="gene ID" value="VDA_001296"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031BX8">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="235605at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="660" mass="75006" checksum="9C14A062313F9B8D" modified="2010-01-19" version="1">MAKVSSVVNNIHCHKIMSHKYASKMNASIEKIISGKEYSYQIRTTRILGEFFTFCFEHNLQMTTGSDVSLCFSAWQEKYFDGNTNKQPYTLISNARALKIALSRLCSHSIRGLPETNHIAPLRRLNTTVFSNTVNSRSKVLGGFDLSTDIQGKSLTLALETDIDIFLGDLISTMKKHRDVIYNISKRYLLDASDRFNFREKVVAKIDRSLFDDNPDLLHPTRVSCKGQRYSLFNSDLSNGKCGKDNLLAYIWHCKRGFVNRDFSGANNNLYKHSKNRFELREYFGLSTLSAVACCNIIIVESGINVDSIRNLSLSSQGSTNQIFEPTPNGFRISYHKARAKAHFKRTLKHVTTEPFIERAFDYLVTATSHHRTFVSGNTSKRLFLYQSSSTSNSIIPVSDMAFKSGFIRLLREAKQLLEQNPSWCEDVTPECIDEILNPSLKAKLKENKLLRPTAKKLRTTEGIIRWYESGGNPAVAAKYLGNSEAVSIRNYLPKELQLAVYNQRVRRFQNVLIASATDGKDYQIKALNLKDEAELTEYLSRLEKRIPHWKSIMKTVSANKDKPNTACGAKVTLNICPENIAVMKACHVIAMQRIESGKSVDDSIKELSYVYQALSDYLRTHPDRRLKRTVHKGDLLYEKKTGNYSDIKITKQEVNRGSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW48</accession>
    <name>D0YW48_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase</fullName>
            <ecNumber evidence="4">2.3.1.117</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Tetrahydrodipicolinate N-succinyltransferase</fullName>
            <shortName evidence="4">THDP succinyltransferase</shortName>
            <shortName evidence="4">THP succinyltransferase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Tetrahydropicolinate succinylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">dapD</name>
        <name evidence="6" type="ORF">VDA_001330</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(S)-2,3,4,5-tetrahydrodipicolinate + H2O + succinyl-CoA = (S)-2-succinylamino-6-oxoheptanedioate + CoA</text>
            <dbReference type="Rhea" id="RHEA:17325"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15685"/>
            <dbReference type="ChEBI" id="CHEBI:16845"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="EC" id="2.3.1.117"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; LL-2,6-diaminopimelate from (S)-tetrahydrodipicolinate (succinylase route): step 1/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homotrimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.117" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297867.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001330"/>
    <dbReference type="EnsemblBacteria" id="EEZ40305">
        <property type="protein sequence ID" value="EEZ40305"/>
        <property type="gene ID" value="VDA_001330"/>
    </dbReference>
    <dbReference type="GeneID" id="57339770"/>
    <dbReference type="eggNOG" id="COG2171">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1251912at2"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00019"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008666">
        <property type="term" value="F:2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019877">
        <property type="term" value="P:diaminopimelate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02122">
        <property type="entry name" value="DapD_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019876">
        <property type="entry name" value="DapD_gammaproteobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032784">
        <property type="entry name" value="THDPS_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038361">
        <property type="entry name" value="THDPS_M_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026586">
        <property type="entry name" value="Type2_DapD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14602">
        <property type="entry name" value="Hexapep_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14789">
        <property type="entry name" value="THDPS_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03536">
        <property type="entry name" value="DapD_gpp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0220">Diaminopimelate biosynthesis</keyword>
    <keyword evidence="4" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="THDPS_M" evidence="5">
        <location>
            <begin position="131"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Succinyl-CoA binding" evidence="4">
        <location>
            <begin position="278"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Succinyl-CoA binding" evidence="4">
        <location>
            <begin position="316"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-anhydride intermediate" evidence="4">
        <location>
            <position position="220"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
            <note>ligand shared between trimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="222"/>
        </location>
        <ligand>
            <name>succinyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="237"/>
        </location>
        <ligand>
            <name>succinyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="240"/>
        </location>
        <ligand>
            <name>succinyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="263"/>
        </location>
        <ligand>
            <name>succinyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="286"/>
        </location>
        <ligand>
            <name>succinyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="303"/>
        </location>
        <ligand>
            <name>succinyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF14789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="343" mass="36038" checksum="68E2128408439AA6" modified="2010-01-19" version="1">MARFSLALGTATKNRDGKIIEAYFPTPILNPSDALVDEIAAVVTYKEGNQAVEVTSEQCVALASIFAAHDQAESALFASKAVNSAQPLVLVILANDETPVSVAEAFLKLQLISHRLVKPHGLVLDGIFGLLHNIAWTNKGAIDLPELAERQMEARLNGETIIVDCVDKFPKMVDYVVPTGVRIADTSRVRLGAHVGEGTTVMHEGFINFNAGTTGVSMVEGRISAGVVVGNGSDIGGGASIMGTLSGGGKVVVSIGENSLLGANAGLGFPMGDRCTIESGLYVTAGSKVQMLDASGKPVEVVKARDLAGKPDLLFRRNSMTGQIECLTNKTAIELNSELHKNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW63</accession>
    <name>D0YW63_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GGDEF domain family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001348</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297896.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001348"/>
    <dbReference type="EnsemblBacteria" id="EEZ40323">
        <property type="protein sequence ID" value="EEZ40323"/>
        <property type="gene ID" value="VDA_001348"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3706">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GGDEF" evidence="2">
        <location>
            <begin position="386"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="4"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="300"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="516" mass="59670" checksum="606A0A7D0F9ECF41" modified="2010-01-19" version="1">MTNLLNVASEISELKQRLDQAQLNYRDQTFKSRRELTILKRLISRLIAVCIGLDSELDRKLLELKAELEQPKEITQLIPRLAIIERLVILQAEKNKKSSHQLQQQFQHSGEALTRFGGLPAPLKRDVLELMQQSTQDRHGLRLHVSQLLALYQRALTLKATTKQNSELSVSYCQQLQQLSAELMQLTTEVDVSGETFQQLQTIQHQLLQDVEPDKLIEMALTVLQMELKHNKQQRKQSQHFINQLHGDLAAAQKNTQHSHEQFHYLHQQRQTVNVELSDITTTLTNNLQQQNLETLRPVFEQLVQELKILTERNQALEKREQTIIEQLNYSGNKLQLVLDQTETYHQQLEDEEQRLYLDPLTQLHNQAALRHRLEQEFQRWIRYKNTTVVAIIDLNRFKKINELYGYGAGDKALKIIAKSLSSHLQSTDFIARSQGDEFVIILPDTTKDQAHKILEQIQSNTQNLPFRFRQQGVTITTTACASVISAQYSPDELLQQLKLTVIQHSSDASTALTWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW91</accession>
    <name>D0YW91_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Phospho-N-acetylmuramoyl-pentapeptide-transferase</fullName>
            <ecNumber evidence="9">2.7.8.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">UDP-MurNAc-pentapeptide phosphotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">mraY</name>
        <name evidence="10" type="ORF">VDA_001173</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>di-trans,octa-cis-undecaprenyl phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine = di-trans-octa-cis-undecaprenyl diphospho-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UMP</text>
            <dbReference type="Rhea" id="RHEA:28386"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:60392"/>
            <dbReference type="ChEBI" id="CHEBI:61386"/>
            <dbReference type="ChEBI" id="CHEBI:61387"/>
            <dbReference type="EC" id="2.7.8.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="9">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the glycosyltransferase 4 family. MraY subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.13" evidence="9"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297570.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001173"/>
    <dbReference type="EnsemblBacteria" id="EEZ40151">
        <property type="protein sequence ID" value="EEZ40151"/>
        <property type="gene ID" value="VDA_001173"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0472">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1151822at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008963">
        <property type="term" value="F:phospho-N-acetylmuramoyl-pentapeptide-transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051992">
        <property type="term" value="F:UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine:undecaprenyl-phosphate transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06852">
        <property type="entry name" value="GT_MraY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00038">
        <property type="entry name" value="MraY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000715">
        <property type="entry name" value="Glycosyl_transferase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003524">
        <property type="entry name" value="PNAcMuramoyl-5peptid_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018480">
        <property type="entry name" value="PNAcMuramoyl-5peptid_Trfase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22926">
        <property type="entry name" value="PTHR22926"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00953">
        <property type="entry name" value="Glycos_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10555">
        <property type="entry name" value="MraY_sig1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00445">
        <property type="entry name" value="mraY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01347">
        <property type="entry name" value="MRAY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01348">
        <property type="entry name" value="MRAY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 9" id="KW-0132">Cell division</keyword>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0133">Cell shape</keyword>
    <keyword evidence="9" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="22"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="73"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="97"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="134"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="172"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="200"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="239"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="263"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="290"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="338"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ40151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="360" mass="40228" checksum="C713BE6C9991FC1E" modified="2010-01-19" version="1">MIYWLAHVLESTFPFFRLFEYLTFRAIMSILTALVLSLWMGPRLIARLQMLQIGQVVRNEGPESHFSKRGTPTMGGIMILAAITITVLLWADLSNPYVWAVLFVLLGYGAVGFVDDYRKVVRKNTDGLIARWKYFWQSLIAIIVAFALYAYGKDTAATQLVVPFFKDIMPQLGLFYIILTYFVIVGTSNAVNLTDGLDGLAIMPTVMVAGGMAFIAWATGNYNYAEYLHIPYVKDASELVVVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLALGGALGTIAVLIRQEFLLVLMGGVFVMETVSVILQVGSYKLRGQRIFRMAPIHHHYELKGWPEPRVIVRFWIITLMLVLIALATLKVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWA2</accession>
    <name>D0YWA2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Cell division protein FtsZ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ftsZ</name>
        <name evidence="9" type="ORF">VDA_001180</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5">Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="4">Assembles at midcell at the inner surface of the cytoplasmic membrane.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the FtsZ family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297584.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001180"/>
    <dbReference type="EnsemblBacteria" id="EEZ40158">
        <property type="protein sequence ID" value="EEZ40158"/>
        <property type="gene ID" value="VDA_001180"/>
    </dbReference>
    <dbReference type="GeneID" id="57339965"/>
    <dbReference type="eggNOG" id="COG0206">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1009041at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000917">
        <property type="term" value="P:division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043093">
        <property type="term" value="P:FtsZ-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051258">
        <property type="term" value="P:protein polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02201">
        <property type="entry name" value="FtsZ_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00909">
        <property type="entry name" value="FtsZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000158">
        <property type="entry name" value="Cell_div_FtsZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020805">
        <property type="entry name" value="Cell_div_FtsZ_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045061">
        <property type="entry name" value="FtsZ/CetZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024757">
        <property type="entry name" value="FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30314">
        <property type="entry name" value="PTHR30314"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12327">
        <property type="entry name" value="FtsZ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00423">
        <property type="entry name" value="CELLDVISFTSZ"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="SSF52490"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="SSF55307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00065">
        <property type="entry name" value="ftsZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01134">
        <property type="entry name" value="FTSZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01135">
        <property type="entry name" value="FTSZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4 5 9" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 4 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0717">Septation</keyword>
    <feature type="domain" description="Tubulin" evidence="7">
        <location>
            <begin position="13"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin_C" evidence="8">
        <location>
            <begin position="207"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="331"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="21"/>
            <end position="25"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="108"/>
            <end position="110"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ40158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="382" mass="40009" checksum="83C7994699452FAC" modified="2010-01-19" version="1">MFEPMMDISDEAVIKVVGVGGGGGNAVDHMVRESIEGVQFISVNTDAQALRKSSVSTVIQIGGDITKGLGAGANPQVGRDSALEDREAIKKELEGSDMVFIAAGMGGGTGTGAAPIIAEIAKELGILTVAVVTKPFSFEGKKRMAFAEQGIEELSKHVDSLITIPNEKLLKVLGRGITLLDAFAKANDVLKNAVQGIAELITRPGMINVDFADVRTVMSEMGHAMMGSGMASGDDRAEEAAEMAISSPLLEDIDLAGARGVLVNITAGLDMRLDEFETVGNTVKAFASDNATVVIGTSLDPDMTDELRVTVVATGIGKDTKPDITLVTSSKPQPVVQERPAQTAAPVVEEKPAVEGQAAAQKKPQAEHDYLDIPAFLRKQAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWP9</accession>
    <name>D0YWP9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8 13">Glutamyl-tRNA reductase</fullName>
            <shortName evidence="8">GluTR</shortName>
            <ecNumber evidence="4 8 13">1.2.1.70</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">hemA</name>
        <name evidence="17" type="ORF">VDA_001445</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8 13">
            <text>(S)-4-amino-5-oxopentanoate + NADP(+) + tRNA(Glu) = H(+) + L-glutamyl-tRNA(Glu) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:12344"/>
            <dbReference type="Rhea" id="RHEA-COMP:9663"/>
            <dbReference type="Rhea" id="RHEA-COMP:9680"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57501"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="EC" id="1.2.1.70"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8 13">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; 5-aminolevulinate from L-glutamyl-tRNA(Glu): step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="domain">
        <text evidence="8">Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="8">During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8 13">Belongs to the glutamyl-tRNA reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.70" evidence="4 8 13"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298074.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001445"/>
    <dbReference type="EnsemblBacteria" id="EEZ40419">
        <property type="protein sequence ID" value="EEZ40419"/>
        <property type="gene ID" value="VDA_001445"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0373">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1358620at2"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00316"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008883">
        <property type="term" value="F:glutamyl-tRNA reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00087">
        <property type="entry name" value="Glu_tRNA_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000343">
        <property type="entry name" value="4pyrrol_synth_GluRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015896">
        <property type="entry name" value="4pyrrol_synth_GluRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015895">
        <property type="entry name" value="4pyrrol_synth_GluRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018214">
        <property type="entry name" value="GluRdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036453">
        <property type="entry name" value="GluRdtase_dimer_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036343">
        <property type="entry name" value="GluRdtase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006151">
        <property type="entry name" value="Shikm_DH/Glu-tRNA_Rdtase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00745">
        <property type="entry name" value="GlutR_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05201">
        <property type="entry name" value="GlutR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01488">
        <property type="entry name" value="Shikimate_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000445">
        <property type="entry name" value="4pyrrol_synth_GluRdtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69075">
        <property type="entry name" value="SSF69075"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69742">
        <property type="entry name" value="SSF69742"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01035">
        <property type="entry name" value="hemA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00747">
        <property type="entry name" value="GLUTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8 11" id="KW-0521">NADP</keyword>
    <keyword evidence="6 8 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7 8 13" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GlutR_N" evidence="16">
        <location>
            <begin position="6"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="Shikimate_DH" evidence="15">
        <location>
            <begin position="170"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="GlutR_dimer" evidence="14">
        <location>
            <begin position="318"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8 10">
        <location>
            <begin position="49"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8 10">
        <location>
            <begin position="112"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8 9">
        <location>
            <position position="50"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 11">
        <location>
            <begin position="187"/>
            <end position="192"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for activity" evidence="8 12">
        <location>
            <position position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000445-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000445-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000445-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000445-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF01488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF05201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EEZ40419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="417" mass="45737" checksum="E13E8E09EAFD8E43" modified="2010-01-19" version="1">MTLLALGINHKTATVDLREKVAFSPEKLTRALQELELHPEVTSGVIVSTCNRTEVYCDISQSGPGVIIDWLTNFHQITAEELMPSLYFYEEQAAARHLMRVACGLDSLVLGEPQILGQVKQSYSDAKDNDAVQGTLEKLFQKTFTVAKRVRTETDIGGNAVSVAFAACTLARQIFESLHGVSVLLVGAGETIELVARHIVEQGCSSLIVANRTRERAEKFSTEFGAEVIGLEQIPEHLHRADIVISSTASPLPIIGKGMVENALKARRHQPMLLVDIAVPRDIEAEVGELNDAYLYSVDDLHSIVEKNREQRKVAAIQAEAIVSEESAAFMSWLRSLEAVDSIRQYRHHAEEIKGELLTRSLQAIASGANPEKVLAELSNKLTNKLIHAPTKAMQQAAHNGDPDKLAVIRETLGLDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWS0</accession>
    <name>D0YWS0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 12">Phosphate acetyltransferase</fullName>
            <ecNumber evidence="6 12">2.3.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11 12">Phosphotransacetylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">VDA_001465</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Involved in acetate metabolism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>acetyl-CoA + phosphate = acetyl phosphate + CoA</text>
            <dbReference type="Rhea" id="RHEA:19521"/>
            <dbReference type="ChEBI" id="CHEBI:22191"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.1.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 12">Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="12">The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 12">In the N-terminal section; belongs to the CobB/CobQ family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.8" evidence="6 12"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001465"/>
    <dbReference type="EnsemblBacteria" id="EEZ40439">
        <property type="protein sequence ID" value="EEZ40439"/>
        <property type="gene ID" value="VDA_001465"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0280">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0857">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00340">
        <property type="reaction ID" value="UER00459"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008959">
        <property type="term" value="F:phosphate acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006085">
        <property type="term" value="P:acetyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1390.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10950">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010766">
        <property type="entry name" value="DRTGG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016475">
        <property type="entry name" value="P-Actrans_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004614">
        <property type="entry name" value="P_AcTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042113">
        <property type="entry name" value="P_AcTrfase_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042112">
        <property type="entry name" value="P_AcTrfase_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002505">
        <property type="entry name" value="PTA_PTB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028979">
        <property type="entry name" value="Ser_kin/Pase_Hpr-like_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07085">
        <property type="entry name" value="DRTGG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01515">
        <property type="entry name" value="PTA_PTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006107">
        <property type="entry name" value="PhpActrans_proteobac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75138">
        <property type="entry name" value="SSF75138"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00651">
        <property type="entry name" value="pta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12 15" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8 12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 12 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DRTGG" evidence="14">
        <location>
            <begin position="233"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="PTA_PTB" evidence="13">
        <location>
            <begin position="391"/>
            <end position="706"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00021528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR006107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF07085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEZ40439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="715" mass="76887" checksum="FF388BE33B365283" modified="2010-01-19" version="1">MSRTIMLIPVGAGVGLTSVSLGVLRAMERKGVRVSFFKPIAQPRQGGEQPDLTTTIIRANSDMQIADPLSMASAEELIRNDQTDVLLEEIVARFKAATANSEVALIEGLVPTRKHPFANQINFEIAKTLDAEIVFVVSPGTDNASQLKERIEVACSNFGGIKNKQISGVIVNKLNAPVDSEGRTRPDLSEIFDDAEAALSSNVEVMQVFNSSPIRVLGCAPWSPELIATRATDIAQHLNAEVLNEGEIATRRIKSITFCARSIPHMVEHFRPGSLLVTSADRPDVIVAACLAAMNGVEIGALLLTGGYDLPKPVMDLCERAFATGLPVLSAQGNTWQTSLNLQSFSLEVPADDKERVEFVNEYMASHIDGQWIESLTEGSTRERRLSPPAFRYQLTELARSAAKRIVLPEGDEPRTVKAAAICAERGIAECVLLGNPEEIKRVAEQQGVTLGAGVTIINSDEVRENYVARLVELRGAKGMTEVVAREKLQDSVFLGTMMLENNEVDGLVSGAVHTTANTIVPPFQIIKTAPDASIVSSVFFMLLPDQVLVYGDCAINPDPTAEQLAEIAIQSADSAKAFGIDPRVAMISYSTGTSGKGADVDKVREATRIAQEKRPDLVIDGPLQYDAAIMENVAASKAPNSPVAGKATVFVFPDLNTGNTTYKAVQRSADLVSIGPMLQGMRKPVNDLSRGALVDDIVYTVALTAIQAKQAETN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWX2</accession>
    <name>D0YWX2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Lipopolysaccharide assembly protein B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">lapB</name>
        <name evidence="4" type="ORF">VDA_001805</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the LapB family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298735.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001805"/>
    <dbReference type="EnsemblBacteria" id="EEZ40773">
        <property type="protein sequence ID" value="EEZ40773"/>
        <property type="gene ID" value="VDA_001805"/>
    </dbReference>
    <dbReference type="GeneID" id="57342080"/>
    <dbReference type="eggNOG" id="COG2956">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1425742at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031235">
        <property type="term" value="C:intrinsic component of the cytoplasmic side of the plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008653">
        <property type="term" value="P:lipopolysaccharide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046890">
        <property type="term" value="P:regulation of lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00994">
        <property type="entry name" value="LPS_assembly_LapB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030865">
        <property type="entry name" value="LapB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041166">
        <property type="entry name" value="Rubredoxin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18073">
        <property type="entry name" value="Rubredoxin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13176">
        <property type="entry name" value="TPR_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="topological domain" description="Cytoplasmic" evidence="2">
        <location>
            <begin position="21"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="Rubredoxin_2" evidence="3">
        <location>
            <begin position="355"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="357"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="360"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="371"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="374"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF18073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="389" mass="44731" checksum="5DEB1D979DF88F1A" modified="2010-01-19" version="1">MLELLFLLLPIAAAYGWYMGNRSASNDRQEQSNHMSRQYVAGLNMLLSDESDKAVDIFIELLQVDSETIDTHLALGNLFRSRGEVERAIKIHQNLIARPNLTIEQRNLSLQQLAKDYMVAGLFDRAEKIFGQLLDEPDYRKSALQQLLNIYQRTREWEKAIDMASQLVKMGEAKLKHDIAHYWCELAMIELGAQNPDKAIQDIKKALSVDKQCVRASLMMARIHIQNQEYKQAIKYLEKVIDQDIDFVGEALPLLLECYQATNSESTWLKYLQLCVERKVGATAELMLADEIAHREGPVMAQTFMTRQLQKNPTMRGFYQLMDYHLDEAEEGRAKESLTSLRHLVGEQLKMKPHYRCRQCGFAAHSLYWQCPSCKSWGSVKPIRGLDGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWZ6</accession>
    <name>D0YWZ6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002049</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299277.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002049"/>
    <dbReference type="EnsemblBacteria" id="EEZ41017">
        <property type="protein sequence ID" value="EEZ41017"/>
        <property type="gene ID" value="VDA_002049"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5525">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="576433at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008866">
        <property type="entry name" value="Phage_lambda_GpA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05876">
        <property type="entry name" value="Terminase_GpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="697" mass="79690" checksum="78D31410D43DB437" modified="2010-01-19" version="1">MSLKQFDSRLGLEFADAKEIRRKLAYLCAPTDKTPVEAADEGLWISDGTDVTKFLSSQVPYMREPLNCLSRRIYEAVIVCGPARSGKTKALVEGWINYAVTQAPGDMLLIYSTKTKASDMSKVDLERSFNATSAIAKLRTGRKSDDNITSKKFKNGMNLKLDSATETSLSASTYRYAGATDYDRADDAVGQEGSKFELMLMRVQNAKSSGMVMAESSPGRVVRNPKREEELAPHEAQPCGGIMELYNQGDRRRFYWLCMDCCAYFQPSFETLKWEENADPLVASKQTWMECPRCGHRHFESQKQQMNMEGRWFREGEIDCYGYVVTETAAIRTSKWATFWFEGVIAAYASWENLVYRYLNAQVIYQDSGDEESLKAFMNVRMGRPYIMQSRGQEIGAHQLMARAADYERSIIPFGGRFLIMTIDVQGGKQNPRFVVQAQVFGEGLQRWVIDRFEILTNPNRNNDRINPMIYAEDWDLLIDEVIKKTYPLADGSGRMMKPVLTLCDSGGSGEKKKGRQKTSSVTDHAYQFYNRLKSLGLSHLFRLVKGASRDIEDLVKETYPDKRSKLANGEIPLLQLHTNRLKNRVAASFSRLEFGARFFHLPGWAERVWFDELTVEFIDEYGHWQKPDGARNESFDLCAYAEAGMYYKGGDDINWNNPPIWAEEWQLNSNVVDADQSPKFERQVRRRYNHSRGIFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX32</accession>
    <name>D0YX32_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Hypothetical outer membrane lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001906</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40874">
        <property type="protein sequence ID" value="EEZ40874"/>
        <property type="gene ID" value="VDA_001906"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="61" mass="6232" checksum="507D81824B3A6497" modified="2010-01-19" version="1">MGALAGGLSDEGVVKGAALGGTSGFIAGDLAGRSKDLDDAQYVLRKCLENKGYTVLDKRDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX44</accession>
    <name>D0YX44_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminodeoxychorismate synthase</fullName>
            <ecNumber evidence="1">2.6.1.85</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001838</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.6.1.85" evidence="1"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298790.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001838"/>
    <dbReference type="EnsemblBacteria" id="EEZ40806">
        <property type="protein sequence ID" value="EEZ40806"/>
        <property type="gene ID" value="VDA_001838"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0147">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1786019at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046820">
        <property type="term" value="F:4-amino-4-deoxychorismate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009396">
        <property type="term" value="P:folic acid-containing compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005802">
        <property type="entry name" value="ADC_synth_comp_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005801">
        <property type="entry name" value="ADC_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019999">
        <property type="entry name" value="Anth_synth_I-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006805">
        <property type="entry name" value="Anth_synth_I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015890">
        <property type="entry name" value="Chorismate_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11236">
        <property type="entry name" value="PTHR11236"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04715">
        <property type="entry name" value="Anth_synt_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00425">
        <property type="entry name" value="Chorismate_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00095">
        <property type="entry name" value="ANTSNTHASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56322">
        <property type="entry name" value="SSF56322"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00553">
        <property type="entry name" value="pabB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Anth_synt_I_N" evidence="4">
        <location>
            <begin position="25"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="Chorismate_bind" evidence="3">
        <location>
            <begin position="204"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="469" mass="52784" checksum="7053FBBCCA50048B" modified="2010-01-19" version="1">MICKSHPQLVVQAIDYHKNVTQSWFEPLAGQPWAMILRSAADDHPDNRFDILVADPLATLQTQNDTTCIKFSNGDEKVTTDDPFTVLEQLKQQLTPDIKGIPDIPFVGGAVGYFSYDLGRQVESIPSIAQHDIHQPDMAVGIYDWALIADHKEQKAFLISPRDSQRFEWLEQQRDQAQLQHNKNKPQHSDDFMLTTDWSSNMTKEVYCNKFNKVREYILSGDCYQINLAQRFSAQYQGDEWQAYCHLEQKNGAPFSSFIRTESGAIISVSPERFLQLKQKAIETKPIKGTRPRHHDVVQDKALAVELQQSTKDQAENVMIVDLLRNDIGRVAKPGSVEVPHLFAVESFPAVHHLVSTVTGTLDDQYQATDLLRACFPGGSITGAPKVRAMEIIEELEPHRRSVYCGSIGYISRCGNMDTSITIRTLVAENNTIYAWAGGGLVLDSQADSEYQETLDKLGKILPTLPRQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX92</accession>
    <name>D0YX92_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001951</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299000.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001951"/>
    <dbReference type="EnsemblBacteria" id="EEZ40919">
        <property type="protein sequence ID" value="EEZ40919"/>
        <property type="gene ID" value="VDA_001951"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0845">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1992451at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="347" mass="39266" checksum="7EF3E14BA8D92CEB" modified="2010-01-19" version="1">MKVQFHTETQVDPKSSNFMNVIYGSAKRGGYRLRWYLLLLLIISPILYLAYFMYQSIYLTIAPGIITTSPMLITATNDGIIDFVVNGDELYTKKSVLVTINNETISNTEHYLSLKTQEIDAQIEKLPAINLDKYNQEIKNAKSSFLKVNEIKKLYEKYRKQGQVSQVDYANIINTASVAKQRELQSSISKEQALFSYDQNKLAGPLMLLRNDIGLKLISYQSQQNELSIVSPVSGFIVENYVTEGQWVQKGQELMTIAPYRQPEVISYVDAKYLAKVAKGSEVMVQLPNGGQYSAIVRSKPRLATKLPSQLTTPFTETKAVLKVVLEFNNHVNDLDWVEGMPVKVII</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXE7</accession>
    <name>D0YXE7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001626</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298399.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001626"/>
    <dbReference type="EnsemblBacteria" id="EEZ40599">
        <property type="protein sequence ID" value="EEZ40599"/>
        <property type="gene ID" value="VDA_001626"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2802">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1474822at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046336">
        <property type="entry name" value="Lon_prtase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="191" mass="22523" checksum="3EE84D1135A340BC" modified="2010-01-19" version="1">MSQHIPLLLQKRHILPTGRMFIRILPGVQTETLKASLEDCSELGICMYENTDKDQRFYHIATRVHVDDFDLAIYDNSLTINISGIDNGFINEIRQDHEGVIWGDYSSIPKWQEMKTQQTHKLLAERLEIMYRSHPELAQQHQEKQFDNLTWLCQRWLEILPLPTSEKQLLINRPNCLDTCDYLMSMMLEPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXH9</accession>
    <name>D0YXH9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">3-oxoacyl-[acyl-carrier-protein] reductase</fullName>
            <ecNumber evidence="4">1.1.1.100</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001686</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 4">Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a (3R)-hydroxyacyl-[ACP] + NADP(+) = a 3-oxoacyl-[ACP] + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:17397"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="EC" id="1.1.1.100"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.100" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298513.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001686"/>
    <dbReference type="EnsemblBacteria" id="EEZ40657">
        <property type="protein sequence ID" value="EEZ40657"/>
        <property type="gene ID" value="VDA_001686"/>
    </dbReference>
    <dbReference type="GeneID" id="57342233"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1601931at2"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004316">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011284">
        <property type="entry name" value="3oxo_ACP_reduc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01830">
        <property type="entry name" value="3oxo_ACP_reduc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="3 4" id="KW-0521">NADP</keyword>
    <keyword evidence="4 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="151"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="12"/>
            <end position="15"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="37"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="59"/>
            <end position="60"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="151"/>
            <end position="155"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR611284-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR611284-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU366074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="244" mass="25626" checksum="2AC104F951070D28" modified="2010-01-19" version="1">MSLEGKIALVTGASRGIGRAIAEILVERGATVIGTATSESGAEAISAYLGDKGQGMALNVTSPESIEAVLKQIKETFGDVDILVNNAGITRDNLLMRMKDDEWQDIMDTNLTSIFRLSKAVLRAMMKKRNGRIISIGSVVGTMGNAGQTNYAAAKAGLLGFTKSMAREVASRGITVNAVAPGFIETDMTRALNDDQRAATLANVPAGRLGDPREIAAAVAFLASDDAAYITGETLHVNGGMYMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXL4</accession>
    <name>D0YXL4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cobalt-zinc-cadmium resistance protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_001755</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001755"/>
    <dbReference type="EnsemblBacteria" id="EEZ40723">
        <property type="protein sequence ID" value="EEZ40723"/>
        <property type="gene ID" value="VDA_001755"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3965">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="SSF161111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="27"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="65"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="136" mass="14923" checksum="D8009A13414AA58E" modified="2010-01-19" version="1">MVMCLLSFVSAIDAILAGGRHVNEGIAVVFGVVNVIGCYLTYWHLAKAHKKTKSALVEAESKQWVMDTVISAAVLMGFVVAQILSMTQYGDYAVYADPAMVIIASLYFALVPVKMVWGAITKMRRVYQHHQAVEAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXM6</accession>
    <name>D0YXM6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative integral membrane efflux protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001767</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40735">
        <property type="protein sequence ID" value="EEZ40735"/>
        <property type="gene ID" value="VDA_001767"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2978">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015558">
        <property type="term" value="F:secondary active p-aminobenzoyl-glutamate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902604">
        <property type="term" value="P:p-aminobenzoyl-glutamate transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004697">
        <property type="entry name" value="AbgT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30282">
        <property type="entry name" value="PTHR30282"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03806">
        <property type="entry name" value="ABG_transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="143"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="207"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="268"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="305"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="348"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="385"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="414"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="444"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="475"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="513" mass="55237" checksum="BDF855E4F361D0C8" modified="2010-01-19" version="1">MTMDVDVLKPSKRSWLDNIEAIGNKIPDITMLFFMATLLCIGLSAVLSWFTFEYIHPLTKQPIEVINLFTSSELMALFTSMVKNFVNFPPLGIVIVATLGIGIAEGSGYISTALKKLLSFVPLSVVTPSVIFIGILAHVASDSAYVILMPVSAYIFYKTGKHPLAGIAAGFAGLAGGFTASYTPSIIDPILAGFTETGARVLDPTYSVNVLCNFFYSFASTFAVIGCCWYVTDKIVEPRLKKSMPIDVAQQDESSETLTAKETKAFKVANYSMLALVAVVVALMVPENSLFRAPDGSLTSPQAPAMQVIVPLLLVFFALPGLVYGFVSQRFQSAKDVTKSMENITASLISFIVFAFFCAQFLYCFGKSNIGSLIALSGAEALKAINLPGQVTILGVILLTACLNLIITSASSKWAILAPVLVPMLMAVGLSPELTQAAFRISDSAVNVSTPMFAFYPLIISYMQRYSSQSGIGTLVSMMVPYSIGLLVTLTAMLYLFWGLDIPLGFNSGYTYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXP0</accession>
    <name>D0YXP0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DNA polymerase III epsilon subunit</fullName>
            <ecNumber evidence="4">2.7.7.7</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001739</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.7.7" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298603.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001739"/>
    <dbReference type="EnsemblBacteria" id="EEZ40707">
        <property type="protein sequence ID" value="EEZ40707"/>
        <property type="gene ID" value="VDA_001739"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0847">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1985371at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Exonuclease_RNaseT/DNA_pol3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Exonuclease" evidence="3">
        <location>
            <begin position="51"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="242" mass="27855" checksum="243195500D664698" modified="2010-01-19" version="1">MQEIAHFIRGGQAPDWQQRYQDRLSKTQDLRLRHFYQTGMIDGKTPLKDVPFVALDFETTGLNSKTDDIVSIGLIPFTIHRIYSKQAQHWVVKPKRPLAEESVVIHGITHSDIQAAPDLRRILDQVLDALAGKVVVVHYKTIERQFMDAALQLRIGEGIEFPVVDTLALEYEIERQKHSGFWNRLRGRRPGSVRLNKCRERYGLPTYQPHHALTDAIATAELLQAQIAYHFTPETPICQIWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXU4</accession>
    <name>D0YXU4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Serine-type D-Ala-D-Ala carboxypeptidase</fullName>
            <ecNumber evidence="4">3.4.16.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">VDA_002107</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the peptidase S11 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.4" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002107"/>
    <dbReference type="EnsemblBacteria" id="EEZ41075">
        <property type="protein sequence ID" value="EEZ41075"/>
        <property type="gene ID" value="VDA_002107"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1686">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009002">
        <property type="term" value="F:serine-type D-Ala-D-Ala carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015956">
        <property type="entry name" value="Peniciliin-bd_prot_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018044">
        <property type="entry name" value="Peptidase_S11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012907">
        <property type="entry name" value="Peptidase_S11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037167">
        <property type="entry name" value="Peptidase_S11_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001967">
        <property type="entry name" value="Peptidase_S11_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07943">
        <property type="entry name" value="PBP5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00768">
        <property type="entry name" value="Peptidase_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00725">
        <property type="entry name" value="DADACBPTASE1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00936">
        <property type="entry name" value="PBP5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69189">
        <property type="entry name" value="SSF69189"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 16" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="9" id="KW-0133">Cell shape</keyword>
    <keyword evidence="11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="8 16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="domain" description="PBP5_C" evidence="15">
        <location>
            <begin position="238"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="12">
        <location>
            <position position="22"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="12">
        <location>
            <position position="25"/>
        </location>
    </feature>
    <feature type="active site" evidence="12">
        <location>
            <position position="85"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR618044-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR618044-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU004016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EEZ41075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="348" mass="38453" checksum="0788E86B2BC6FF45" modified="2010-01-19" version="1">MDYHTGRVLVEHNANEKLNPASLTKLMTSYVAGQEMKQGNISKDDVVVISRNAWARNFHDSSKMFIEVGAEVPMMDLFRGLIIQSGNDASVAIAEHVAGSQDAFVGLMNSWAKKLNMNNSRFANAHGLDHDDLYSTPYDIALLGQALIRDLPDIYPLYSEKSFTYNNITQRNRNGLLHDSSMNVDGMKTGYTGGAGYSLASSATEGDMRLIAVVMGTKSPKIRQAESKQLLNYGFRFFDTVSPHKAGDEIMTERIWMGDKEQVKLGVAETSYVTLSRNDVKKMTASVEMTGQLEAPIEKGQQVGKVIYSVDGKDVASQPLVALETVNEGSFFSKIIDMVKKFVYGLFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXY7</accession>
    <name>D0YXY7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ClpB protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_002150</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the ClpA/ClpB family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299546.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002150"/>
    <dbReference type="EnsemblBacteria" id="EEZ41118">
        <property type="protein sequence ID" value="EEZ41118"/>
        <property type="gene ID" value="VDA_002150"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0542">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="44062at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017729">
        <property type="entry name" value="ATPase_T6SS_ClpV1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036628">
        <property type="entry name" value="Clp_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004176">
        <property type="entry name" value="Clp_R_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018368">
        <property type="entry name" value="ClpA/B_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028299">
        <property type="entry name" value="ClpA/B_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041546">
        <property type="entry name" value="ClpA/ClpB_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17871">
        <property type="entry name" value="AAA_lid_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02861">
        <property type="entry name" value="Clp_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81923">
        <property type="entry name" value="SSF81923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03345">
        <property type="entry name" value="VI_ClpV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51903">
        <property type="entry name" value="CLP_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00870">
        <property type="entry name" value="CLPAB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00871">
        <property type="entry name" value="CLPAB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Clp R" evidence="8">
        <location>
            <begin position="10"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="868" mass="96757" checksum="E05FF789B1E819AD" modified="2010-01-19" version="1">MIRIELPVLIEKLNSQTKLALEQAAALCISRGNSEVTFEHLLFTLLDNPLSDVRELIKLSGLEHDAIKLICGDSLPKESGNDTYPAFSPLLVELLQDAWLLASTELDSHELRSGIIFLAALLRPDRYLAFSLIKQFENINRETVRKQFSQLLVNSSETPVITSREKVTNKSLIGGESGLQRFCTDFTQQARSGKLDPVLCRDDEINLMIDILCRRRKNNPIVVGDAGVGKSAVVEGLALRIVEGKVPQALKDVQLWSLDLGLMQAGASVKGEFEKRLKSILDEVKNSPTPIILFIDEAHTLIGAGNQEGGGDAANLLKPALARGEVCTVAATTWKEYKKYFEKDPALTRRFQLVKLDEPTAAQATDILRGLHCVYEAAHQVLISDDALKAAAELSARYVSGRQLPDKAIDVLDTACARIAINLSAPPRRISEIDSQCHQRQLEIEMLSRQQKLGKTIDQEHFDHLLAEEERDRAEQDRLHLAWQEQKEIVSEIIKTRQALLKQVAKDGDSNEMDTLRNQLQQCYQKLEQIPHDQRLIHPEVDATQIAEVIADWTGVPVDQMNTDELTKITHLPEILSQAIKGQDVAIECIHRHLLTARADLRRPGRPKGAFLLVGPSGVGKTETVVQLAEQLYGGQQFLTTINMSEYQEKHTVSRLIGSPPGYVGFGEGGVLTEAIRKMPYSIVLLDEVEKAHPEVLNLFYQAFDKGELADGEGRVIDCQNIVFFLTSNLGYQTIVDYAEQPDQIEDKLYPELAAFFKPALLARMEVVPYLPLNHDVLEKIVRGKLSRLEKLLVSRYKAEVVIEPCLIEEILGRATRSENGARMLEAIIEGQMLPPVSLALLNKLAHREAVTRICLTVVDGDFVGEVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY80</accession>
    <name>D0YY80_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002243</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299722.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002243"/>
    <dbReference type="EnsemblBacteria" id="EEZ41211">
        <property type="protein sequence ID" value="EEZ41211"/>
        <property type="gene ID" value="VDA_002243"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3265">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1758621at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="178" mass="20176" checksum="03E10AC4CFEEE5A3" modified="2010-01-19" version="1">MTPSLNLTYAPNVLFLFGLSGAGKSYVGDVIGQNSGWHVYHADEDLTQEMRRVISEQKPFTEQMRDDFFVKIVSRIKQLQKQHKKIVVTQGAYKNKHRHYLLQSIDDLELIMVSASDSLIHKRLEHRHNGISNQSAAAIKHVFETPNHLAHVIENNEGSEFIIQQLNALYANARSAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYA9</accession>
    <name>D0YYA9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="13">CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase</fullName>
            <ecNumber evidence="13">2.7.8.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">VDA_002272</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="10">Phospholipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.5" evidence="13"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002272"/>
    <dbReference type="EnsemblBacteria" id="EEZ41240">
        <property type="protein sequence ID" value="EEZ41240"/>
        <property type="gene ID" value="VDA_002272"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0558">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00848">
        <property type="reaction ID" value="UER00151"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008444">
        <property type="term" value="F:CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004570">
        <property type="entry name" value="Phosphatidylglycerol_P_synth"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000847">
        <property type="entry name" value="Phos_ph_gly_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00560">
        <property type="entry name" value="pgsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="9" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="167"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ41240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="198" mass="23021" checksum="D724D7EB9031EABD" modified="2010-01-19" version="1">MLCEFFIIRIKIMRLSIPNILSFVRLILIPFFVIAFYLPYEWSPFATALIFFIAGVTDWFDGYLARRLNQTTRFGAFIDPVADKLMVATALVLVVEHYHSVWVTIPAVTMIGREIIISALREWMAEIGKRASVAVSWVGKVKTASQMFALLMLLWRPYEWTVWLGYISLYAAMVLTYWSMIQYLLAAKDDLLDERHHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYD1</accession>
    <name>D0YYD1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Protease HtpX</fullName>
            <ecNumber evidence="12">3.4.24.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Heat shock protein HtpX</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">htpX</name>
        <name evidence="14" type="ORF">VDA_002294</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="12">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cell membrane</location>
            <topology evidence="12">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the peptidase M48B family.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="12"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299807.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002294"/>
    <dbReference type="MEROPS" id="M48.002"/>
    <dbReference type="EnsemblBacteria" id="EEZ41262">
        <property type="protein sequence ID" value="EEZ41262"/>
        <property type="gene ID" value="VDA_002294"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0501">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1918093at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00188">
        <property type="entry name" value="Pept_M48_protease_HtpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022919">
        <property type="entry name" value="Pept_M48_protease_HtpX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 12" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 12" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4 12" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12 14" id="KW-0346">Stress response</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8 12" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="162"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="193"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M48" evidence="13">
        <location>
            <begin position="78"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="active site" evidence="12">
        <location>
            <position position="144"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="223"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEZ41262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="293" mass="31908" checksum="FD624D54BCCDD012" modified="2010-01-19" version="1">MKRILLFLATNLAVMLVFSIVLNIIFAVTGIKSTSMGGLLVMAALFGFGGSLISLMMSKSMALRSVGGMVIEHPRNETEHWLMETVARQAQQAGIGMPTVAIYDAHDINAFATGAKRDDALVAVSTGLLHSMTRDEAEAVLAHEISHISNGDMVTMTLMQGVVNTFVIFISRLVAGAISGVNNNDEEGEGGSYMTYFIVSSIMEVLFGFLASILTMWYSRHREFKADAGSAHLVGKQKMIAALERLKMSHEEPHLEGSMMAFGINGKKSLSELFMTHPPLEKRIEALRTGEHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYG1</accession>
    <name>D0YYG1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">L,D-transpeptidase YcbB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_002324</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the YkuD family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002324"/>
    <dbReference type="EnsemblBacteria" id="EEZ41292">
        <property type="protein sequence ID" value="EEZ41292"/>
        <property type="gene ID" value="VDA_002324"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2989">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071972">
        <property type="term" value="F:peptidoglycan L,D-transpeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd16913">
        <property type="entry name" value="YkuD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.101.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005490">
        <property type="entry name" value="LD_TPept_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045380">
        <property type="entry name" value="LD_TPept_scaffold_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002477">
        <property type="entry name" value="Peptidoglycan-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036365">
        <property type="entry name" value="PGBD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036366">
        <property type="entry name" value="PGBDSf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038063">
        <property type="entry name" value="Transpep_catalytic_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01471">
        <property type="entry name" value="PG_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20142">
        <property type="entry name" value="Scaffold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03734">
        <property type="entry name" value="YkuD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141523">
        <property type="entry name" value="SSF141523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47090">
        <property type="entry name" value="SSF47090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Scaffold" evidence="6">
        <location>
            <begin position="92"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="PG_binding_1" evidence="4">
        <location>
            <begin position="282"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="YkuD" evidence="5">
        <location>
            <begin position="342"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF20142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="582" mass="66905" checksum="C7F1F949F7370945" modified="2010-01-19" version="1">MKTFSTLSLCIACTLGYSCQIHAYHLDIEPFPLEQKNAMDNAMHIEIAQLYDPSRDVGSTQLDHYFNPKYQAALDWVKDIPSIQSVISYPDKLAEIYYTNGYQPYWSSKEAIEALLANLKIFEIAKISPDLTKRYTKIMQLKNTQDWKQIDLLATDTMLALLSFYQYSKHEQREWLFGGKMKWPLPLPSHHEIESFLTASETAQMVKYISSLQGNNEQYTSNIKALEKLTQLSHKRWPIFHVANKVSLGNPLPNAKNLITILEMLGDLPSYQAEQMLTENLDYLSPTLIEAVKSFQQRHGLSPDGVIGPNTLYWLSKSPQERLRVVALNTLRLSLWPDEQPNQIVVNIPAYELTARLNNQSVMTSKVIVGRPSRNTPMMDSTITSVVFNPYWNVPTSIMRKDILPKVKRNPSYLTRNRYEILSSWSNPARISVNAINWRGVNPKTFPYRLRQKPGNKNALGRFKFNIPNDYAIYLHDTSSKRLFNKSDRALSSGCVRVEYAKGLAQLLLEYSGVSDKRFIQYSSRTRTKTVVLKNKIPVHLIYQTAWAEGNGLIYYRDDIYHYDKMGGASQNGKLYITAYNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYL7</accession>
    <name>D0YYL7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methyltranfer_dom domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299991.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002380"/>
    <dbReference type="EnsemblBacteria" id="EEZ41348">
        <property type="protein sequence ID" value="EEZ41348"/>
        <property type="gene ID" value="VDA_002380"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502Z7Q4">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1557981at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13679">
        <property type="entry name" value="Methyltransf_32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltranfer_dom" evidence="1">
        <location>
            <begin position="124"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="398" mass="45871" checksum="B5F59672472E81E9" modified="2010-01-19" version="1">MANYFDSFSHLDELLTQSRCFWQFMPFSQLDYQWRETYPELCEWLENLSEAQLAEYQNNAELLAHTLKKWIPPSVELFNATSLAFLPQKETELPRGSDTGIPGRKWQQITAFTSALPKLGLPWLEWCAGKGHLGRVLALSHQQPVVSLEWQDQLCIDGEAMAQHLNLPITFVQADAFAKESQQHIKTEQHAVALHACGDLHTSLLQHCAAKQAAAVSISPCCYHLIRSDFYQMLSEYGKKTQLQLSKHDLRLPLQETVTAGQRVQALRETEVSFRLGFDALQRHVRDVDEYLSVPNTQKALFNQGFSAFCHWAAEKKSINLAGLDIDYDYWLAEGKRRFQISERMELVRQLFRRPLEMWLVLDRACFMVEQGYQVEIGLFCEKPMTPRNILINAYISK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYQ4</accession>
    <name>D0YYQ4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002417</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300051.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002417"/>
    <dbReference type="EnsemblBacteria" id="EEZ41385">
        <property type="protein sequence ID" value="EEZ41385"/>
        <property type="gene ID" value="VDA_002417"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0517">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="763914at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007069">
        <property type="entry name" value="Transposase_32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026889">
        <property type="entry name" value="Zn_Tnp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04986">
        <property type="entry name" value="Y2_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14319">
        <property type="entry name" value="Zn_Tnp_IS91"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn_Tnp_IS91" evidence="1">
        <location>
            <begin position="7"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="352" mass="41309" checksum="FEBB2B5651D79444" modified="2010-01-19" version="1">MTFQSLLRDYYDDFCATYSTQINHDIRYAMKAILTCHTEKQGHSRWQCSHCEHQSEYAMSCGHRHCSQCQHQATSDWLAKQQQKLLPVDYFMVTFTLPAELRYLAKKHTKALYQAMFTVTASVIKSFANNDKHLGNRIGFTSVLHTHNRRRDLHPHIHMVITGGGFDDKKRQWKNCKNKYLFNAFALAKVWRARLLAYLTTELKWALPDHITKKWVVDCRHVGQGKPALLYLSTYLYRGVIADKDILFIHHDQVTFRYKESQTQTMKTRTLPVLQFLWLILQHVLPKGFRRVRDYGLLRGHEKKRLQAIQFMFMLAGQLTLPSPNKTVHIKAQPFCPCCQHVMQLTGIFRPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYT9</accession>
    <name>D0YYT9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_002452</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300119.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002452"/>
    <dbReference type="EnsemblBacteria" id="EEZ41420">
        <property type="protein sequence ID" value="EEZ41420"/>
        <property type="gene ID" value="VDA_002452"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1305">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1099526at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025840">
        <property type="entry name" value="7TM_transglut"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025838">
        <property type="entry name" value="Transglut_i_TM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14402">
        <property type="entry name" value="7TM_transglut"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14400">
        <property type="entry name" value="Transglut_i_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="307"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="341"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="379"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="410"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="439"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="469"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="domain" description="Transglut_i_TM" evidence="2">
        <location>
            <begin position="24"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="7TM_transglut" evidence="3">
        <location>
            <begin position="257"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="503" mass="55899" checksum="E1D8907458A446B9" modified="2010-01-19" version="1">MTSRVPFYFLISILITVGLALSIYRHEVYGVPWTPGEHRQVWELEARVEFDAIGEPVKVSMAAPKTQQGFTLIDQSTSSPGYGVATVDNDQGHRIEWTIRDAIGKQILYYKTQMLVDNQSDYKEIAPKGEPATVSLDSPQQTAATALLAQARNLSSDDLTLTRELIKEFNDKQNQNASLLLNSLTREQAITNLLSMDGIYSRVVGGLQLEDGRRRQSITPMVEVWDSANKEWQLFNLETGIKGKPENVLIWNQQGHSLLDVVGGRNSNVSFSIIAQDITPQQATQEKVQAEDLLNFSIHSLPIEEQAMFKTIMLVPIGALIVVFLRIIVGLKTSGTFMPVLIAVAFVQTQLLTGILGFLLIVGTGLIIRSYLSKLNLLLVARISAVIITVIMIISVFTVVAYKIGLVEGLSITFFPMIILSWTIERMSILWEEEGAKEVFVQGGGSLLTAVLIYLAMTNPLIRHLTFNFIGLQLIIMAAILLLGTYTGYRISELRRFKPLAED</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYW4</accession>
    <name>D0YYW4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Membrane-bound lytic murein transglycosylase B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002477</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300167.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002477"/>
    <dbReference type="EnsemblBacteria" id="EEZ41445">
        <property type="protein sequence ID" value="EEZ41445"/>
        <property type="gene ID" value="VDA_002477"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2951">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="710313at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043426">
        <property type="entry name" value="MltB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011970">
        <property type="entry name" value="MltB_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031304">
        <property type="entry name" value="SLT_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30163">
        <property type="entry name" value="PTHR30163"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13406">
        <property type="entry name" value="SLT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02283">
        <property type="entry name" value="MltB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019887" evidence="1">
        <location>
            <begin position="23"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="SLT_2" evidence="2">
        <location>
            <begin position="27"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="323" mass="36495" checksum="A25CC2A3FC7E8D87" modified="2010-01-19" version="1">MKKRLVSALVAFGLGMSSSVFAADAGFDKYVEGLKAEAREKGISEQIINEAFTGIEFKHRAVKADKNQPEKKLTLDQYIPRAVPQWKVKQANRLYREHYTDLQRIGKQFGVQPRFIVALWGVESNFGKFTGKYNVVEALATMAYEGRREAFFRGQVMDALQILNEGHIKPSEMKGSWAGAMGQPQFMPSSYLTFAADGNNDGKSDIWNTTEDVFASAANYLHKSGWNDEYTWGRQVKVPTTLNSALIGVERDKGKTLSQWQALGVRTVSGQQLPTEDIQAWLVQPDDQHGRAYLIYENYQTLLKWNRSHYFALAVSHLADQIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYZ0</accession>
    <name>D0YYZ0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 18">Succinate dehydrogenase flavoprotein subunit</fullName>
            <ecNumber evidence="7 18">1.3.5.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">VDA_002503</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 18">
            <text>a quinone + succinate = a quinol + fumarate</text>
            <dbReference type="Rhea" id="RHEA:40523"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.3.5.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 18">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5 18">Carbohydrate metabolism; tricarboxylic acid cycle; fumarate from succinate (bacterial route): step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4 18">Cell inner membrane</location>
            <topology evidence="4 18">Peripheral membrane protein</topology>
            <orientation evidence="4 18">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
            <orientation evidence="3">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6 18">Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.3.5.1" evidence="7 18"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002503"/>
    <dbReference type="EnsemblBacteria" id="EEZ41471">
        <property type="protein sequence ID" value="EEZ41471"/>
        <property type="gene ID" value="VDA_002503"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1053">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER01005"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008177">
        <property type="term" value="F:succinate dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022900">
        <property type="term" value="P:electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.700.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-binding_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003952">
        <property type="entry name" value="FRD_SDH_FAD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037099">
        <property type="entry name" value="Fum_R/Succ_DH_flav-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015939">
        <property type="entry name" value="Fum_Rdtase/Succ_DH_flav-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030664">
        <property type="entry name" value="SdhA/FrdA/AprA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027477">
        <property type="entry name" value="Succ_DH/fumarate_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011281">
        <property type="entry name" value="Succ_DH_flav_su_fwd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014006">
        <property type="entry name" value="Succ_Dhase_FrdA_Gneg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11632">
        <property type="entry name" value="PTHR11632"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02910">
        <property type="entry name" value="Succ_DH_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46977">
        <property type="entry name" value="SSF46977"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56425">
        <property type="entry name" value="SSF56425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01816">
        <property type="entry name" value="sdhA_forward"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01812">
        <property type="entry name" value="sdhA_frdA_Gneg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00504">
        <property type="entry name" value="FRD_SDH_FAD_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="18" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="18" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="13 18" id="KW-0249">Electron transport</keyword>
    <keyword evidence="12 18" id="KW-0274">FAD</keyword>
    <keyword evidence="11 18" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="15 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="14 18 21" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 18" id="KW-0813">Transport</keyword>
    <keyword evidence="10 18" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="FAD_binding_2" evidence="19">
        <location>
            <begin position="1"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="Succ_DH_flav_C" evidence="20">
        <location>
            <begin position="441"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="16">
        <location>
            <position position="267"/>
        </location>
    </feature>
    <feature type="modified residue" description="Tele-8alpha-FAD histidine" evidence="17">
        <location>
            <position position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00008040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00019965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR611281-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR611281-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU362051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF00890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF02910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="EEZ41471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="569" mass="62606" checksum="4D0C744FD6C5F0BE" modified="2010-01-19" version="1">MRAALQISEQGLKCALLSKVFPTRSHTVSAQGGITVALGNSHPDNWQWHMYDTVKGSDYIGDQNAIEYMCLNGPKSVIELEKMGLPFSRFDNGTIYQRPFGGQSKEFGGEQAARTAAAADRTGHALLHTLYQQNIKHKTTIFSEWYALDLVKNQDGAILGCTALCMETGEICYFKSKATILATGGAGRIYASTTNAHINTGDGVGMALRAGVPMQDMEMWQFHPTGIAGAGVLVTEGCRGEGGYLLNKDGERFMERYAPNAKDLAGRDVVARSMMVEIREGRGCDGPWGPHIKLKLDHLGKEVLESRLPGICELSRTFAHVDPVKEPIPVIPTCHYMMGGVPTQVSGQAIKQNVSGQDVDVQGLFACGEIASVSVHGANRLGGNSLLDLVVFGRATGLHLGETLLAQTEARPATDSDIEASLSRLNRWNRTQQGEDPVQIRKDLQTCMQNSFSVFREGDAMAEGLKELKQIRERLNEARLDDTSTEFNTQRIECLELDNLMETAMATAVAANYRTESRGAHARFDFPERDDENWLCHTIYNPETESMSQRAVNMTPIHREAFPPKVRSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ06</accession>
    <name>D0YZ06_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Asparagine synthetase [glutamine-hydrolyzing]</fullName>
            <ecNumber evidence="9">6.3.5.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_002519</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the asparagine synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.4" evidence="9"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300243.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002519"/>
    <dbReference type="EnsemblBacteria" id="EEZ41487">
        <property type="protein sequence ID" value="EEZ41487"/>
        <property type="gene ID" value="VDA_002519"/>
    </dbReference>
    <dbReference type="GeneID" id="57341252"/>
    <dbReference type="eggNOG" id="COG0367">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="610569at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004066">
        <property type="term" value="F:asparagine synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006529">
        <property type="term" value="P:asparagine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01991">
        <property type="entry name" value="Asn_Synthase_B_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00712">
        <property type="entry name" value="AsnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006426">
        <property type="entry name" value="Asn_synth_AEB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001962">
        <property type="entry name" value="Asn_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033738">
        <property type="entry name" value="AsnB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00733">
        <property type="entry name" value="Asn_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13537">
        <property type="entry name" value="GATase_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001589">
        <property type="entry name" value="Asn_synthetase_glu-h"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01536">
        <property type="entry name" value="asn_synth_AEB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0061">Asparagine biosynthesis</keyword>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 5" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="9" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="8">
        <location>
            <begin position="2"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="active site" description="For GATase activity" evidence="5">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="273"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="347"/>
            <end position="348"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for beta-aspartyl-AMP intermediate formation" evidence="7">
        <location>
            <position position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="556" mass="62662" checksum="33F07435BB89D93D" modified="2010-01-19" version="1">MCSIFGILDIKSDSSALRTTALEMSKKMRHRGPDWSGIYSSDRAILVHERLAIVDLNSGEQPLYNQDKTHALAVNGEIYNHKELRAEFAPDYPFQTESDCEIILALYKEKGPELLDYLNGIFGFILYDAEQDAYLIGRDHIGIIPLYQGYDEHGNYYVASEMKALVPVCKTISEFPPGHFLWSKKGEPVRYYKRDWMEFDAVKDAVTDKQKLADALESAVKRQLMTDVPYGVLLSGGLDSSVISAITKKFAARRIEDDEQSQAWWPTLHSFAIGLEGAPDLKAAKVVADHIGTVHHELTYTVQEGLDAIRDVIYHIETYDVTTIRASTPMYLMSRKIRAMGIKMVLSGEGADEVFGGYLYFHKAPNAKEFHEETVRKLLALNMFDCARANKSMAAWGIEARVPFLDKEFLEVAMSINPQDKMCGNGKIEKHIIRECFGHYLPESVAWRQKEQFSDGVGYNWIDTLKAVAEEKVTDQQMETAKFRFPYNTPTTKEAYAYREIFEELFPLESAAHCVPGGPSIACSSAKAIEWDESFKNAADPSGRAVAAVHCDAYKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ28</accession>
    <name>D0YZ28_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">5'-methylthioadenosine nucleosidase/S-adenosylhomocysteine nucleosidase</fullName>
            <ecNumber evidence="3">3.2.2.16</ecNumber>
            <ecNumber evidence="3">3.2.2.9</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002541</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.2.2.16" evidence="3"/>
    <dbReference type="EC" id="3.2.2.9" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300288.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002541"/>
    <dbReference type="EnsemblBacteria" id="EEZ41509">
        <property type="protein sequence ID" value="EEZ41509"/>
        <property type="gene ID" value="VDA_002541"/>
    </dbReference>
    <dbReference type="GeneID" id="57341225"/>
    <dbReference type="eggNOG" id="COG0775">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1860206at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008782">
        <property type="term" value="F:adenosylhomocysteine nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008930">
        <property type="term" value="F:methylthioadenosine nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009116">
        <property type="term" value="P:nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000845">
        <property type="entry name" value="Nucleoside_phosphorylase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01048">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="SSF53167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019858" evidence="1">
        <location>
            <begin position="22"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="PNP_UDP_1" evidence="2">
        <location>
            <begin position="26"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="270" mass="29913" checksum="B48F733BEC004F22" modified="2010-01-19" version="1">MLLLKRGLALIAILFSCQIFAQSQPILVQGAMDIETTTLINALDNKKETTMGSWTFWQGTIAGYPVVVSRTEVGIANAAAATTLAIEQFKPKLIINQGTSGGHDPKLYRGDIVLGKTSFNMGAYQVSFKEKGQGIHPENWQNFAVTMRLRENGKPVEHTEFAADSHLLTVAQQQAKSYNKGKVVTGIIGTADEWNREVDRINWFHNTYGTSVEEMETSSAALVAQAYNIPFIGIRILSNTDQHKQDFDPQTAVDCQEFVLGYIKTLIKQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ62</accession>
    <name>D0YZ62_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cytochrome c-type biogenesis protein CcmE</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Cytochrome c maturation protein E</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Heme chaperone CcmE</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ccmE</name>
        <name evidence="4" type="synonym">cycJ</name>
        <name evidence="7" type="ORF">VDA_002575</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the CcmE/CycJ family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300374.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002575"/>
    <dbReference type="EnsemblBacteria" id="EEZ41543">
        <property type="protein sequence ID" value="EEZ41543"/>
        <property type="gene ID" value="VDA_002575"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2332">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1724595at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017003">
        <property type="term" value="P:protein-heme linkage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01959">
        <property type="entry name" value="CcmE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004329">
        <property type="entry name" value="CcmE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036127">
        <property type="entry name" value="CcmE-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34128">
        <property type="entry name" value="PTHR34128"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03100">
        <property type="entry name" value="CcmE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82093">
        <property type="entry name" value="SSF82093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2 4" id="KW-0201">Cytochrome c-type biogenesis</keyword>
    <keyword evidence="1 4 5" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="3 4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="4 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="topological domain" description="Cytoplasmic" evidence="4">
        <location>
            <begin position="1"/>
            <end position="8"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="9"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="topological domain" description="Extracellular" evidence="4">
        <location>
            <begin position="30"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="binding site" description="covalent" evidence="4 5">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="4 5">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR604329-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="159" mass="17569" checksum="3CCEAA2775FE4029" modified="2010-01-19" version="1">MNPRRKKRLTIVIAILIGLSATVGLMLYALNQNMDLFYTPTELVNGKPDGTKPEVGQHLRIGGMVVKGSLKRDPESLKVSFEVEDVGPKVTVIYDGILPDLFREGQGIVAQGVLVNPTTVQASEVLAKHDENYMPPEVADAMKKNHTRLQYTEEQLQGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ65</accession>
    <name>D0YZ65_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter involved in cytochrome c biogenesis ATPase component CcmA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_002578</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300381.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002578"/>
    <dbReference type="EnsemblBacteria" id="EEZ41546">
        <property type="protein sequence ID" value="EEZ41546"/>
        <property type="gene ID" value="VDA_002578"/>
    </dbReference>
    <dbReference type="GeneID" id="57341180"/>
    <dbReference type="eggNOG" id="COG4133">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1833499at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015439">
        <property type="term" value="F:ABC-type heme transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005895">
        <property type="entry name" value="ABC_transptr_haem_export_CcmA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43499">
        <property type="entry name" value="PTHR43499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01189">
        <property type="entry name" value="ccmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0201">Cytochrome c-type biogenesis</keyword>
    <keyword evidence="1 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="2"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="216" mass="24180" checksum="5D993D3FACB2B422" modified="2010-01-19" version="1">MLSIEDLACIRDERMLFEHLNFTISSGELVQIEGHNGAGKTTLLRIIAGLGRADHGVVRWKGEDIVTAREDYHHDLLFLGHSTGVKKELSAYENLAFFQAMHPWEYDSELQGSPRVTGEEALWDALAHVGLAGREDVLAGQLSAGQQRRVALARLWLSNHKLWVLDEPLTAIDKQGVKVLENLFLAHAQRGGMVLLTTHQDMFTDSDHLRKIKLGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZB3</accession>
    <name>D0YZB3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002626</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300529.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41594">
        <property type="protein sequence ID" value="EEZ41594"/>
        <property type="gene ID" value="VDA_002626"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5032UN4">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="322258at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="371" mass="43452" checksum="8607859C59E9F846" modified="2010-01-19" version="1">MTDGFSNNATPKYLGYVYQVLIAIEKCFDAKPNETIWIECFGDIYDGKTFTEVKHHVEEHNLASNSKDIWNTLKNLVVEDSSMFEQIVLHTTSFISERSIFHGWNTLSAHEKLNLIKSHEPSLSIKLLYDKIFEDASDVELLSILSRFTIDQSREHVEEKWKSLLEARKLKCVLEPYRESILHWIYSYVNKNAIVDHRRWKVNINDFDDAFQFQVNRWSGDNIPFPVDRTEYDTEQHADGYLFLLEYRDIGLKGRDRGIALNDYFKAKNSEESLVDLKPDIMPEIINNYLVDVVEKATGYKRQYSYEIDPEDLGTSKSNKIARDAYFEFHNSSVLEVPEVSGTRPYFMRGKVHEAINNTSYTWKYNEEDID</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZD5</accession>
    <name>D0YZD5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glutamate 5-kinase</fullName>
            <ecNumber evidence="8">2.7.2.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Gamma-glutamyl kinase</fullName>
            <shortName evidence="8">GK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">proB</name>
        <name evidence="10" type="ORF">VDA_002648</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>ATP + L-glutamate = ADP + L-glutamyl 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:14877"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58274"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-glutamate: step 1/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the glutamate 5-kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.11" evidence="8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300596.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002648"/>
    <dbReference type="EnsemblBacteria" id="EEZ41616">
        <property type="protein sequence ID" value="EEZ41616"/>
        <property type="gene ID" value="VDA_002648"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0263">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1480250at2"/>
    <dbReference type="UniPathway" id="UPA00098">
        <property type="reaction ID" value="UER00359"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004349">
        <property type="term" value="F:glutamate 5-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04242">
        <property type="entry name" value="AAK_G5K_ProB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00456">
        <property type="entry name" value="ProB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041739">
        <property type="entry name" value="G5K_ProB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001057">
        <property type="entry name" value="Glu/AcGlu_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011529">
        <property type="entry name" value="Glu_5kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005715">
        <property type="entry name" value="Glu_5kinase/COase_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019797">
        <property type="entry name" value="Glutamate_5-kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002478">
        <property type="entry name" value="PUA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036974">
        <property type="entry name" value="PUA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01472">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000729">
        <property type="entry name" value="GK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00474">
        <property type="entry name" value="GLU5KINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00359">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01027">
        <property type="entry name" value="proB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00902">
        <property type="entry name" value="GLUTAMATE_5_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 8" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PUA" evidence="9">
        <location>
            <begin position="291"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="24"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="151"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="183"/>
            <end position="184"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="225"/>
            <end position="231"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ41616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="382" mass="40842" checksum="2D4AA9D33BC3C493" modified="2010-01-19" version="1">MAESKTLTANTKNGADVKHTVVVKLGTSVLTGGTLKLNRAHMVELVRQCAMLRHEGHKVIVVTSGAIAAGREHLGYPELPKTMASKQLLAAVGQSCLIQEWQSLFGIYGFNIGQMLLTRADLNDRERFLNARDMLVALLDNGIIPVVNENDAVATTEIKVGDNDNLSALVGILAGADKLLLLTDQPGLFTADPRSNPDAELIREVHTIDETLRNIAGGSVGGLGTGGMATKLQAADVARRAGIEVVIAAGSRPDVIIDLARGESVGTRFLPLECPLESRKRWILAGPPPAGDIMIDDGAVVAVQERGSSLLPKGITGVKGEFERGEVVRIFNKDGVLLARGISRYSSTDMLKIAGKHSHDIHQILGYEYGHVAIHRDDLVVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZJ8</accession>
    <name>D0YZJ8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Iron binding protein IscA for iron-sulfur cluster assembly</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002711</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HesB/IscA family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002711"/>
    <dbReference type="EnsemblBacteria" id="EEZ41679">
        <property type="protein sequence ID" value="EEZ41679"/>
        <property type="gene ID" value="VDA_002711"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0316">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.300.12">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000361">
        <property type="entry name" value="FeS_biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016092">
        <property type="entry name" value="FeS_cluster_insertion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017870">
        <property type="entry name" value="FeS_cluster_insertion_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035903">
        <property type="entry name" value="HesB-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01521">
        <property type="entry name" value="Fe-S_biosyn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89360">
        <property type="entry name" value="SSF89360"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00049">
        <property type="entry name" value="TIGR00049"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01152">
        <property type="entry name" value="HESB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe-S_biosyn" evidence="2">
        <location>
            <begin position="2"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="70" mass="7823" checksum="0684769E37046514" modified="2010-01-19" version="1">MAYVLEFVDELEEGDEMFEEKGVKIIVDAKSMLYLDGTELDFAKEGLNEGFKFNNPNVSSECGCGESFNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZU0</accession>
    <name>D0YZU0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_002803</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002803"/>
    <dbReference type="MEROPS" id="M23.014"/>
    <dbReference type="EnsemblBacteria" id="EEZ41771">
        <property type="protein sequence ID" value="EEZ41771"/>
        <property type="gene ID" value="VDA_002803"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0739">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1891666at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="28"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M23" evidence="4">
        <location>
            <begin position="172"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="58"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="336" mass="37442" checksum="02CA804B43A7F609" modified="2010-01-19" version="1">MSKANKSVNNKAPIRKLKQEKPRDNKPLIMAGAGFCGTLFALLCYGTFTLYQDAYDNNQQLDLLNRQAQELAASLNEESEMNQKLNAELESKNESLEHLNQRLDDMETVLGLQTDGENPYTLEQHIDSAAIDSAVRATLFRLIPNGMPTPEHIQLTSGFGTRVHPITKKRRSHNGLDFAAKIGTPIYAPADAVIEQARSSNSGYGNHLQLNHAMGFISTYSHLSKFNVKRGQFVRKGDLIGWTGNTGLSTGPHLHYEIRFLGRPLNPKAFVKWTPENFDSLFAKEKSVQWASLLNMINGMVGMQVQLTHDDSTKGLTTAQVTHETSEQDDNKSQTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZU3</accession>
    <name>D0YZU3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002806</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002806"/>
    <dbReference type="EnsemblBacteria" id="EEZ41774">
        <property type="protein sequence ID" value="EEZ41774"/>
        <property type="gene ID" value="VDA_002806"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1396">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039554">
        <property type="entry name" value="HigA2-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13744">
        <property type="entry name" value="HTH_37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="25"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="92" mass="10293" checksum="28147F2F4537858D" modified="2010-01-19" version="1">MASRSQESQDRIAEMADEMLLEVQFQAIREELEITQAELARNMGISQPSVVAIEQRGNDVKLSTIKRYIEAMGGKMSINIELPTGKHVGFNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z058</accession>
    <name>D0Z058_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF2061 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002921</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002921"/>
    <dbReference type="EnsemblBacteria" id="EEZ41889">
        <property type="protein sequence ID" value="EEZ41889"/>
        <property type="gene ID" value="VDA_002921"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018638">
        <property type="entry name" value="DUF2061_membrane"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09834">
        <property type="entry name" value="DUF2061"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2061" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="38" mass="4549" checksum="D0520DF2885CC090" modified="2010-01-19" version="1">MAMIEPAINTVAYYFHEKVWQKKEHNHTLFDAMVCQHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0A4</accession>
    <name>D0Z0A4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thiamine-binding periplasmic protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_002967</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial solute-binding protein 1 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301435.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002967"/>
    <dbReference type="EnsemblBacteria" id="EEZ41935">
        <property type="protein sequence ID" value="EEZ41935"/>
        <property type="gene ID" value="VDA_002967"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4143">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1567509at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030975">
        <property type="term" value="F:thiamine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015888">
        <property type="term" value="P:thiamine transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13545">
        <property type="entry name" value="PBP2_TbpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005967">
        <property type="entry name" value="ThiB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005948">
        <property type="entry name" value="ThiB-like"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01254">
        <property type="entry name" value="sfuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01276">
        <property type="entry name" value="thiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0574">Periplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018778" description="Thiamine-binding periplasmic protein" evidence="7">
        <location>
            <begin position="20"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ41935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="329" mass="37021" checksum="88CE302C427D6018" modified="2010-01-19" version="1">MKKILPLLGLTLLSASVMAQDKPTLTVYTYSSFAADWGPGPKVKRAFEQECGCNLNFVALDDGVSILNRVRLEGSRTKADVLLGLDNNLIEEAKKTGLLAPSGVDTSKVNIPNGWHDPIFVPYDYGYFAFVYNSNKLKQVPSSLDQLIHDQSISVIYQDPRTSTPGQGLMLWIKSVYGDKAPQAWQALAKHTVTVTKGWSEAYNMFLQGEADMVLSYTTSPAYHIIEENKQQYRAADFKEGHYMQVEVAAKLKNSTHPKLADEFMQFILTKPFQSLMATGNWMYPVISEPLPKGFDQLTIPTKALEFSPEKIAQERRSWIREWQQALTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0E9</accession>
    <name>D0Z0E9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ABC-type Fe3+-hydroxamate transport system component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_003013</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301563.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003013"/>
    <dbReference type="EnsemblBacteria" id="EEZ41980">
        <property type="protein sequence ID" value="EEZ41980"/>
        <property type="gene ID" value="VDA_003013"/>
    </dbReference>
    <dbReference type="GeneID" id="57340536"/>
    <dbReference type="eggNOG" id="COG3637">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1258929at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027385">
        <property type="entry name" value="OMP_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026387">
        <property type="entry name" value="OMP_w_GlyGly"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13505">
        <property type="entry name" value="OMP_b-brl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04219">
        <property type="entry name" value="OMP_w_GlyGly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018729" evidence="1">
        <location>
            <begin position="23"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="OMP_b-brl" evidence="2">
        <location>
            <begin position="9"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="206" mass="22568" checksum="F45D46E993999AEB" modified="2010-01-19" version="1">MKKLALSAAVLAATFAAIPAQADTLLGVKVGADAWFADSKVAGHTDDSTSGSYYVSLEHFIPLVPNVEIRYNNIDANNAKFDQTDFTAYYEILDNDLVALDLGLTMTNFSSVNIGPDHFDKWQPSLYGNAEIGIPMTPLAVFTKLNYGNIDSTKTFDGQAGVKFTLPLVVADLNLRGGYRMMDYDFDKARNDVKLDGWFLGAEVDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0H7</accession>
    <name>D0Z0H7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Small ribosomal subunit biogenesis GTPase RsgA</fullName>
            <ecNumber evidence="3">3.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rsgA</name>
        <name evidence="7" type="ORF">VDA_003041</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="3">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.-" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003041"/>
    <dbReference type="EnsemblBacteria" id="EEZ42008">
        <property type="protein sequence ID" value="EEZ42008"/>
        <property type="gene ID" value="VDA_003041"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1162">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01854">
        <property type="entry name" value="YjeQ_EngC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01820">
        <property type="entry name" value="GTPase_RsgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030378">
        <property type="entry name" value="G_CP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004881">
        <property type="entry name" value="Ribosome_biogen_GTPase_RsgA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010914">
        <property type="entry name" value="RsgA_GTPase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32120">
        <property type="entry name" value="PTHR32120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03193">
        <property type="entry name" value="RsgA_GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00157">
        <property type="entry name" value="TIGR00157"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50936">
        <property type="entry name" value="ENGC_GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51721">
        <property type="entry name" value="G_CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CP-type G" evidence="6">
        <location>
            <begin position="119"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="ENGC_GTPASE" evidence="5">
        <location>
            <begin position="136"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="22"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="175"/>
            <end position="178"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="229"/>
            <end position="237"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="311"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="316"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="318"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="324"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ42008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="366" mass="41481" checksum="A10D7CAA6BC3A985" modified="2010-01-19" version="1">MYDNTESQPKLNDILVAKKKKLTQSQSRRVRSNQNKRLNKERDTVQWDEALLESPREGLVITRFGQHADIEDLETHKVHRCNLRRSIRSLVSGDRVVWRPGVEALQGIAGVVEAVHERQSVLTRPDYYDGVKAVAANVDLIVIVSAILPELSLNIIDRYLIAAETVEIEPLIVLNKIDLLDKEQRQQVEETLSLYQDIGYNIRYVSTETGEGMDELKQDLKNHTTIFAGQSGVGKSSMVNTLMPEVDAEVGDVSENSGLGQHTTTAARLYHFEDGGDLIDSPGVREFGLWHLEPEHVTKAFVEFRNYLGGCKFRDCKHKDDPGCILREAVEDGHINQERFDSYHRIIESMSENVANRQFSRNKSAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0I5</accession>
    <name>D0Z0I5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fumarate reductase subunit C</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Quinol-fumarate reductase subunit C</fullName>
            <shortName evidence="5">QFR subunit C</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">frdC</name>
        <name evidence="6" type="ORF">VDA_003049</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Anchors the catalytic components of the fumarate reductase complex to the cell membrane, binds quinones.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the FrdC family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301692.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003049"/>
    <dbReference type="EnsemblBacteria" id="EEZ42016">
        <property type="protein sequence ID" value="EEZ42016"/>
        <property type="gene ID" value="VDA_003049"/>
    </dbReference>
    <dbReference type="GeneID" id="57340476"/>
    <dbReference type="eggNOG" id="COG3029">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2053102at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045284">
        <property type="term" value="C:plasma membrane fumarate reductase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000104">
        <property type="term" value="F:succinate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00546">
        <property type="entry name" value="QFR_TypeD_subunitC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00708">
        <property type="entry name" value="Fumarate_red_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003510">
        <property type="entry name" value="Fumarate_red_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034804">
        <property type="entry name" value="SQR/QFR_C/D"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02300">
        <property type="entry name" value="Fumarate_red_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000180">
        <property type="entry name" value="FrdC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81343">
        <property type="entry name" value="SSF81343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="21"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ42016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="127" mass="14660" checksum="7D6FC07B0BE9F61F" modified="2010-01-19" version="1">MSNRKPYVREMKRTWWKDSSFYRFYMIREATILPLIFFTICLTFGLGSLVKGPEAWQSWLDFMANPIVILLNILALAGSLFHAFTYFNMMPQVMPIQIKGKKVDKKIIILAQWAVVAVISVVVLALV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0L7</accession>
    <name>D0Z0L7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Bifunctional purine biosynthesis protein PurH</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="8">Phosphoribosylaminoimidazolecarboxamide formyltransferase</fullName>
                <ecNumber evidence="8">2.1.2.3</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="8">AICAR transformylase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="8">IMP cyclohydrolase</fullName>
                <ecNumber evidence="8">3.5.4.10</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="8">ATIC</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="8">IMP synthase</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="8">Inosinicase</fullName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="8" type="primary">purH</name>
        <name evidence="10" type="ORF">VDA_003081</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(6S)-10-formyltetrahydrofolate + 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide = (6S)-5,6,7,8-tetrahydrofolate + 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:22192"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
            <dbReference type="ChEBI" id="CHEBI:58467"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="EC" id="2.1.2.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>H2O + IMP = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:18445"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:58467"/>
            <dbReference type="EC" id="3.5.4.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Purine metabolism; IMP biosynthesis via de novo pathway; 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide (10-formyl THF route): step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Purine metabolism; IMP biosynthesis via de novo pathway; IMP from 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide: step 1/1.</text>
    </comment>
    <comment type="domain">
        <text evidence="8">The IMP cyclohydrolase activity resides in the N-terminal region.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the PurH family.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.3" evidence="8"/>
    <dbReference type="EC" id="3.5.4.10" evidence="8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301804.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003081"/>
    <dbReference type="EnsemblBacteria" id="EEZ42048">
        <property type="protein sequence ID" value="EEZ42048"/>
        <property type="gene ID" value="VDA_003081"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0138">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1049662at2"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00133"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003937">
        <property type="term" value="F:IMP cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004643">
        <property type="term" value="F:phosphoribosylaminoimidazolecarboxamide formyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00139">
        <property type="entry name" value="PurH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024051">
        <property type="entry name" value="AICAR_Tfase_dup_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011607">
        <property type="entry name" value="MGS-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036914">
        <property type="entry name" value="MGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002695">
        <property type="entry name" value="PurH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11692">
        <property type="entry name" value="PTHR11692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01808">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02142">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000414">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00798">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00851">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52335">
        <property type="entry name" value="SSF52335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00355">
        <property type="entry name" value="purH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51855">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 8" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="5 8" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MGS-like" evidence="9">
        <location>
            <begin position="1"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ42048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="532" mass="57798" checksum="52B04CC08AB03C8B" modified="2010-01-19" version="1">MENARPIRRALISVSDKTGIVEFAQALVSQGVDILSTGGTARLLADNQIPVTEVSDHTGFPEMMDGRVKTLHPKIHGGILGRREQDDSIMAEHNIAPIDMVVVNLYPFAATVANPDCTLAEAIENIDIGGPTMVRSAAKNHRDVTIIVNAGDYDRVLTEMAANQGSLTLATRFDLAIAAFEHTAAYDGMIANYFGTQVPAYGDSEENQADSIFPRTFNQQFIKKQDMRYGENSHQAAAFYVEAQPQEASVATAHQLQGKALSYNNIADTDAALECVKEFLEPACVIVKHANPCGVALGDNLLDAYNRAYQTDPTSAFGGIIAFNRELDAATAQAIVERQFVEVIIAPSVSAQAAEIVATKQNVRLLESGLWQQEHKTTQWDSKRVNGGLLVQERDQGMVSLQDLEVVSERQPTEDELRDALFCWKVAKYVKSNAIVYAKGNMTIGVGAGQMSRVYSAKIAGIKAADENLEVAGSVMASDAFFPFRDGIDAAAQAGIKCVIQPGGSMRDQEVIDAANEHGMAMIFTKMRHFRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0Q7</accession>
    <name>D0Z0Q7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Type II secretion system protein E</fullName>
            <shortName evidence="3">T2SS protein E</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Type II traffic warden ATPase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_003121</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the GSP E family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003121"/>
    <dbReference type="EnsemblBacteria" id="EEZ42088">
        <property type="protein sequence ID" value="EEZ42088"/>
        <property type="gene ID" value="VDA_003121"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2804">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001482">
        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037257">
        <property type="entry name" value="T2SS_E_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013369">
        <property type="entry name" value="T2SS_GspE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00437">
        <property type="entry name" value="T2SSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160246">
        <property type="entry name" value="SSF160246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02533">
        <property type="entry name" value="type_II_gspE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00662">
        <property type="entry name" value="T2SP_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="T2SP_E" evidence="4">
        <location>
            <begin position="321"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU366070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ42088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="501" mass="55664" checksum="60DE70FF067D842A" modified="2010-01-19" version="1">MDLTPSVDHPLPSLTRLPFSFAKRHKVVLEYNEQGLHLFYSSPLSAAVLAEIRRVTESSFMAVELTAEDFEQKLTESYQRDSSEARQLMEDLGSDSDDFFSLAEELPETEDLLESEDDAPIIKLINAMLAEAIKESASDIHIETFEKVLSIRFRVDGVLREVLQPSRKLAPLLVSRIKVMAKLDIAEKRVPQDGRISLRIGGRAVDVRVSTMPSSHGERVVLRLLDKNATRLDLHSLGMTPSIHTNFSKIIQRPHGIILVTGPTGSGKSTTLYAGLQELNSPDRNILTVEDPIEFDIDGIGQTQVNSKVDMTFARGLRAILRQDPDVVMIGEIRDLETAAIAVQASLTGHMVLSTLHTNTAVGAITRLRDMGIEPFLISSSLLGVLAQRLIRTLCQQCREPYLADNEQKKLFGLSEQEELTLYRPCGCEHCNGKGYRGRTGIHELLLVDDKVQELIHAEAGEQAIEQYIRHTTPSIRADGLSKVRAGITTLEEVMRVTKEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-08-12" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0R1</accession>
    <name>D0Z0R1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">33 kDa chaperonin</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Heat shock protein 33 homolog</fullName>
            <shortName evidence="6">HSP33</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">hslO</name>
        <name evidence="7" type="ORF">VDA_003125</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="6">Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the HSP33 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301939.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003125"/>
    <dbReference type="EnsemblBacteria" id="EEZ42092">
        <property type="protein sequence ID" value="EEZ42092"/>
        <property type="gene ID" value="VDA_003125"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1281">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1406579at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00498">
        <property type="entry name" value="Hsp33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.55.30.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00117">
        <property type="entry name" value="HslO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000397">
        <property type="entry name" value="Heat_shock_Hsp33"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016154">
        <property type="entry name" value="Heat_shock_Hsp33_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016153">
        <property type="entry name" value="Heat_shock_Hsp33_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023212">
        <property type="entry name" value="Hsp33_helix_hairpin_bin_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30111">
        <property type="entry name" value="PTHR30111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01430">
        <property type="entry name" value="HSP33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005261">
        <property type="entry name" value="Heat_shock_Hsp33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118352">
        <property type="entry name" value="SSF118352"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64397">
        <property type="entry name" value="SSF64397"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 6" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0862">Zinc</keyword>
    <feature type="disulfide bond" description="Redox-active" evidence="6">
        <location>
            <begin position="229"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="6">
        <location>
            <begin position="262"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ42092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="292" mass="32363" checksum="2165EA427FFA68D0" modified="2010-01-19" version="1">MTTDNLYRYLFDGVSVRGELVQLGDTYQQIIASKEYPAPIQNLLGELLVATSLLTATLKFEGSITVQLQGDGPVSLAVINGDHDQKLRGVARFEGEIPAINNIHELMGKGYLVITITPTKGERYQGVVGLEGDTLAECLESYFKNSEQLKTRILLRTGEFEGQAKAAGMLLQILPDEQGNEGDFEHLEALTETVKDEELFGLDAQDVLYRLYHQEEVKLFEPQPVSFFCGCSRERSASAIRSIDRAEVDAIVAQEGKVSLHCDYCGTSYNFDSIDVANLFENGQDTNNEQVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0S6</accession>
    <name>D0Z0S6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DNA polymerase III epsilon subunit</fullName>
            <ecNumber evidence="4">2.7.7.7</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_003140</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.7.7" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301980.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003140"/>
    <dbReference type="EnsemblBacteria" id="EEZ42107">
        <property type="protein sequence ID" value="EEZ42107"/>
        <property type="gene ID" value="VDA_003140"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0847">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1985371at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Exonuclease_RNaseT/DNA_pol3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Exonuclease" evidence="3">
        <location>
            <begin position="51"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ42107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="237" mass="26631" checksum="86DB6DA291AF7846" modified="2010-01-19" version="1">MSISQLFKRWSPLEKLQQQRDSYVQQALPNSLSSWLSTPLPPSDSLLSQLEYLVLDFETTGFDPEQDDILSVGFVTISQQRIDLSTATELLIKDSQQKVKPETAIINHITTEKLAHGVELDCAMAALFNAMKGKIMVAHGAMIEQRFLNHYLATRYQLPPLPIIWLDTLTIEKSLSIHRQQLKANDYRLAQIRQRHGLPAYPAHGAVIDAIATAELLLVLQVACFGKKTGTLANWLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0T4</accession>
    <name>D0Z0T4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Probable queuosine precursor transporter</fullName>
            <shortName evidence="1">Q precursor transporter</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003148</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302004.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003148"/>
    <dbReference type="EnsemblBacteria" id="EEZ42115">
        <property type="protein sequence ID" value="EEZ42115"/>
        <property type="gene ID" value="VDA_003148"/>
    </dbReference>
    <dbReference type="GeneID" id="57340622"/>
    <dbReference type="eggNOG" id="COG1738">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1462872at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990397">
        <property type="term" value="P:queuosine salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02088">
        <property type="entry name" value="Q_prec_transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003744">
        <property type="entry name" value="YhhQ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34300">
        <property type="entry name" value="PTHR34300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02592">
        <property type="entry name" value="Vut_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00697">
        <property type="entry name" value="TIGR00697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="154"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="198"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="239" mass="26839" checksum="C178C81DA9DE8030" modified="2010-01-19" version="1">MTDRYSTATSIPSNIQSSFSAAQKQKALGYLVLFHLLVIASSNYLVQLPFTVFGFHTTWGAFTFPFIFLATDLTVRILGAPMARKTVLMVMMPALVISYILSVLFFQGEYQGLAHLGEFNLFVARIAIASFMAYLLGQILDVSVFNRLRQLKQWWIAPTCSTIFGNAIDTLAFFSIAFYQSPDAFMAANWTEIALVDYSFKLIISLGLFVPMYGVLLNYLVRKLTTLPSYNNSPQSQYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0W1</accession>
    <name>D0Z0W1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_003175</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003175"/>
    <dbReference type="EnsemblBacteria" id="EEZ42142">
        <property type="protein sequence ID" value="EEZ42142"/>
        <property type="gene ID" value="VDA_003175"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ42142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="41" mass="4647" checksum="930AD709D6BB769D" modified="2010-01-19" version="1">MVEGEVFYQLEPMLTEDEIEQGWIAPCSAYAKSDLVLDLRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0Y2</accession>
    <name>D0Z0Y2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Oxygen-dependent coproporphyrinogen-III oxidase</fullName>
            <shortName evidence="5">CPO</shortName>
            <shortName evidence="5">Coprogen oxidase</shortName>
            <shortName evidence="5">Coproporphyrinogenase</shortName>
            <ecNumber evidence="5">1.3.3.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">hemF</name>
        <name evidence="6" type="ORF">VDA_003196</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>coproporphyrinogen III + 2 H(+) + O2 = 2 CO2 + 2 H2O + protoporphyrinogen IX</text>
            <dbReference type="Rhea" id="RHEA:18257"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57307"/>
            <dbReference type="ChEBI" id="CHEBI:57309"/>
            <dbReference type="EC" id="1.3.3.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; protoporphyrinogen-IX from coproporphyrinogen-III (O2 route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1 5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the aerobic coproporphyrinogen-III oxidase family.</text>
    </comment>
    <dbReference type="EC" id="1.3.3.3" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302131.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003196"/>
    <dbReference type="EnsemblBacteria" id="EEZ42163">
        <property type="protein sequence ID" value="EEZ42163"/>
        <property type="gene ID" value="VDA_003196"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0408">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1086432at2"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00322"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004109">
        <property type="term" value="F:coproporphyrinogen oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042803">
        <property type="term" value="F:protein homodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1500.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00333">
        <property type="entry name" value="Coprogen_oxidas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001260">
        <property type="entry name" value="Coprogen_oxidase_aer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036406">
        <property type="entry name" value="Coprogen_oxidase_aer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018375">
        <property type="entry name" value="Coprogen_oxidase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10755">
        <property type="entry name" value="PTHR10755"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01218">
        <property type="entry name" value="Coprogen_oxidas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000166">
        <property type="entry name" value="Coproporphyri_ox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00073">
        <property type="entry name" value="COPRGNOXDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102886">
        <property type="entry name" value="SSF102886"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01021">
        <property type="entry name" value="COPROGEN_OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 5" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="110"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Important for dimerization" evidence="5">
        <location>
            <begin position="242"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="260"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="108"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for dimerization" evidence="5">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ42163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="303" mass="35314" checksum="7ABD759A4ADAA8B8" modified="2010-01-19" version="1">MAFIDKEAVKTFLLQLQDQICRALEQQDGVAQFEQDDWQREQGGGGRTRVLRHGQVFEQAGVNFSHVFGVEMPASATAHRPELAGRRFEAMGVSLVIHPHNPYVPTSHANVRFFIAEKEGEAPVWWFGGGFDLTPFYPFAEDCLHWHQVAHQLCQPFGDAVYSQHKAWCDRYFFLPHRNETRGIGGLFFDDLNQWEFDNCFAYIQAVGQGYLEAYLPIVEKRKSHCFGERERQFQLYRRGRYVEFNLVYDRGTLFGLQSGGRTESILMSMPPLARWEYDYQVEPNSAEAELYQYYLKPRNWIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z135</accession>
    <name>D0Z135_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7 8">DNA replication and repair protein RecF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">recF</name>
        <name evidence="10" type="ORF">VDA_003249</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7 8">The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7 8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the RecF family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302284.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003249"/>
    <dbReference type="EnsemblBacteria" id="EEZ42216">
        <property type="protein sequence ID" value="EEZ42216"/>
        <property type="gene ID" value="VDA_003249"/>
    </dbReference>
    <dbReference type="GeneID" id="57340340"/>
    <dbReference type="eggNOG" id="COG1195">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="891841at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00365">
        <property type="entry name" value="RecF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001238">
        <property type="entry name" value="DNA-binding_RecF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018078">
        <property type="entry name" value="DNA-binding_RecF_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042174">
        <property type="entry name" value="RecF_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32182:SF0">
        <property type="entry name" value="PTHR32182:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00611">
        <property type="entry name" value="recf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00617">
        <property type="entry name" value="RECF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00618">
        <property type="entry name" value="RECF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7 8" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0742">SOS response</keyword>
    <feature type="domain" description="SMC_N" evidence="9">
        <location>
            <begin position="3"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="30"/>
            <end position="37"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ42216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="360" mass="40688" checksum="E9E6D9E4AAF57D84" modified="2010-01-19" version="1">MALTRLIVKDFRNIADCDLELSPSFNFLIGANGSGKTSVLEAVHYLGHGRSFRSHLTGRVIRHEQSELFVHGRVQGEGTQLPQPVGINKKRDGTTEVKIAGEGNQKLAQLAQILPLQLITPEGFDLLIGGPKFRRAFIDWGVFYVEPKFFQAWSRLKRLTKQRNALLKTATSYRELSYWDQELAQLAEQIDLWRSDYLAAVKQKANEICLGFLPEFDIQLGYYRGWEKETPYGELLRRNFERDCQLGYTASGPHKADLRIKVAGTPVEDVLSRGQLKLMVCALRLAQGLHLTEVTGKQCIYLIDDFASELDSHRRALLAQRLKETHAQVFISAISADQITDMQDEKGKMFLVEHGKITAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z145</accession>
    <name>D0Z145_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Enoyl-CoA hydratase/delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase</fullName>
            <ecNumber evidence="14">1.1.1.35</ecNumber>
            <ecNumber evidence="14">4.2.1.17</ecNumber>
            <ecNumber evidence="14">5.1.2.3</ecNumber>
            <ecNumber evidence="14">5.3.3.8</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">VDA_003259</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a (3S)-3-hydroxyacyl-CoA + NAD(+) = a 3-oxoacyl-CoA + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:22432"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57318"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
            <dbReference type="EC" id="1.1.1.35"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism; fatty acid beta-oxidation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.35" evidence="14"/>
    <dbReference type="EC" id="4.2.1.17" evidence="14"/>
    <dbReference type="EC" id="5.1.2.3" evidence="14"/>
    <dbReference type="EC" id="5.3.3.8" evidence="14"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302316.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003259"/>
    <dbReference type="EnsemblBacteria" id="EEZ42226">
        <property type="protein sequence ID" value="EEZ42226"/>
        <property type="gene ID" value="VDA_003259"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1024">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1250">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="977512at2"/>
    <dbReference type="UniPathway" id="UPA00659"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036125">
        <property type="term" value="C:fatty acid beta-oxidation multienzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003857">
        <property type="term" value="F:3-hydroxyacyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008692">
        <property type="term" value="F:3-hydroxybutyryl-CoA epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004165">
        <property type="term" value="F:delta(3)-delta(2)-enoyl-CoA isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004300">
        <property type="term" value="F:enoyl-CoA hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006180">
        <property type="entry name" value="3-OHacyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006176">
        <property type="entry name" value="3-OHacyl-CoA_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006108">
        <property type="entry name" value="3HC_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018376">
        <property type="entry name" value="Enoyl-CoA_hyd/isom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012799">
        <property type="entry name" value="FadB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00725">
        <property type="entry name" value="3HCDH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02737">
        <property type="entry name" value="3HCDH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02437">
        <property type="entry name" value="FadB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00067">
        <property type="entry name" value="3HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00166">
        <property type="entry name" value="ENOYL_COA_HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="14" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="5 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3HCDH_N" evidence="13">
        <location>
            <begin position="318"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="domain" description="3HCDH" evidence="12">
        <location>
            <begin position="495"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="domain" description="3HCDH" evidence="12">
        <location>
            <begin position="626"/>
            <end position="705"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEZ42226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="726" mass="79507" checksum="CCDC72EA52078CB3" modified="2010-01-19" version="1">MIYQGETLYVDYIEPGIAELCLHASGSINKFDLATLESLNQALNALYQQPDLKGLLLTSSKDSFIVGADITEFLGLFAQSEPELLQWLNYANSIFNKLEDIPVPTVSAISGYALGGGCECVLACDFRIGTPTTKIGLPETKLGIMPGFGGTVRLPRLIGADSAMEIITTGKEQTASQALKMGLLDAIVDTENLHQSALNLLHNTIDTTINWQPRRSQKQQPLALNHTEAMMSFTTAKAMVAKLAGPHYPAPMMAVKTIENAAQLSRAEALQIESTNFVKLAKSSEAQALIGLFLGDQKLKAAAKKAAKESSLIEHSMVLGAGIMGGGIAYQSAVKGIQVTMKDIAPASLDLGMTEAAKLLNKRLERGRIDGLKMAQILGRINPTLSYPQQTPQIIVEAVVENPKIKMAVLQEVEAATPATTVLTSNTSTIPIDLLAQGLTRPEQFCGMHFFNPVHKMPLVEIIRGKATSEQTIQQVVSYAKQMGKTPVVVNDCPGFFVNRVLFPYFAAFSQLVNDGIDFQRIDKIMERQFGWPMGPAYLLDVVGIDTAHHAQAVMAEGYPDRMAKVHKDAIDVLFENKRFGQKNGSGFYNYQLDKKGKPKKTLAPEVTQLLNSLCQQPLDLSDQQIMERMMIPMINEVVLCLEQQIIADPADGDMALIYGLGFPPFIGGVFRYLDNLGLDNYLRLTKQYQQLGTLYSVPSSLQEMAKKQQTYYPKPNSTLNLHTQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-02-10" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1D5</accession>
    <name>D0Z1D5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative capsule O-acetyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_003349</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302547.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003349"/>
    <dbReference type="EnsemblBacteria" id="EEZ42316">
        <property type="protein sequence ID" value="EEZ42316"/>
        <property type="gene ID" value="VDA_003349"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0110">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1878940at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ42316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="243" mass="27068" checksum="BBF62A4674460614" modified="2010-01-19" version="1">MKTHLFSNKNPIAFIQRIQSHLACFIKKSVIYISKLHTNQVEITAPKKSLIKIRFKKSQQNRVIIDENFQGHLTLNFSGNNNHVYIGKNVSLDHSSINITQNNSRLIIEDNVTIGRENKISLNDVAASPMIKIGRDCMLSSNVSLRTFDSHPLYDLNDQLLNSGKGDLVLQPHCWIGQDTKILKGVTIGKGSVIGTGSIVTKSLPSHTIAAGIPAKIIKQGEFYWAREHSPLSQQQGKTLSFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1F0</accession>
    <name>D0Z1F0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative NlpD-related protein family M37 unassigned peptidase (NlpD protein)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_003364</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003364"/>
    <dbReference type="EnsemblBacteria" id="EEZ42331">
        <property type="protein sequence ID" value="EEZ42331"/>
        <property type="gene ID" value="VDA_003364"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4942">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018768" evidence="2">
        <location>
            <begin position="31"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M23" evidence="3">
        <location>
            <begin position="297"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="36"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="159"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ42331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="395" mass="43700" checksum="8C44B52DBE790F74" modified="2010-01-19" version="1">MIKHLNQTIRAGALCTGALLCLAFVTPSYATSPNQLDSVKQEIARQKSQLAKKQQEFAALQKELRQHELGIGKTAKQIHQAQAQLETLKRSIAQLESEQKKLEAEQKKQQQQLKALLDAQYRQGKNSEIANLLSGENSSTLDRMTAYAETFSLAQTKALENLEVTNTELQMKLHQLSTQREQQRAMLSQLQQEKAELDSQQKAREKTLAGIKGKIRTSNDYINDLKANERRMLAAIAKAKAEAEARARAEAAAKKAAEAAKRLPMNGLSSSKGKLPWPVRGSVIHNYGDRQQGELRWKGMVIAKPVGSQVTAISSGRVVFADWLRGYGLMIVIEHGKGDMSIYGYNQTLLKKVGDPVSAGEPIALVGDSGGQDRSGLYFEIRRKGSPVNPRSWLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1F3</accession>
    <name>D0Z1F3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein-export protein SecB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">secB</name>
        <name evidence="4" type="ORF">VDA_003367</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the SecB family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302581.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003367"/>
    <dbReference type="EnsemblBacteria" id="EEZ42334">
        <property type="protein sequence ID" value="EEZ42334"/>
        <property type="gene ID" value="VDA_003367"/>
    </dbReference>
    <dbReference type="GeneID" id="57340183"/>
    <dbReference type="eggNOG" id="COG1952">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1624074at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051262">
        <property type="term" value="P:protein tetramerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00821">
        <property type="entry name" value="SecB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003708">
        <property type="entry name" value="SecB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035958">
        <property type="entry name" value="SecB-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36918">
        <property type="entry name" value="PTHR36918"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02556">
        <property type="entry name" value="SecB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01594">
        <property type="entry name" value="SECBCHAPRONE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54611">
        <property type="entry name" value="SSF54611"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00809">
        <property type="entry name" value="secB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0811">Translocation</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ42334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="155" mass="17162" checksum="90FA6E9B65409DB8" modified="2010-01-19" version="1">MAEAANNDAQQNFQIQRIFLKDVSFEAPNSPDVFQKEWNPEVKLDLDTQSRELGEGVYEVVLRLTVTVQNEGDNAFLCEVQQGGIFTALGMEAPQLAHCLGAFCPNILFPYARETISSLVVKGTFPQLNLAPVNFDALFMNYLQSQAEANTEADA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1F7</accession>
    <name>D0Z1F7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_003371</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302590.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003371"/>
    <dbReference type="EnsemblBacteria" id="EEZ42338">
        <property type="protein sequence ID" value="EEZ42338"/>
        <property type="gene ID" value="VDA_003371"/>
    </dbReference>
    <dbReference type="GeneID" id="57340179"/>
    <dbReference type="eggNOG" id="COG5002">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="692375at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032404">
        <property type="entry name" value="CpxA_peri"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038515">
        <property type="entry name" value="CpxA_peri_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16527">
        <property type="entry name" value="CpxA_peri"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="9">
        <location>
            <begin position="183"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="8">
        <location>
            <begin position="244"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="266"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ42338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="453" mass="51831" checksum="92C2A9C7C3B6CAEB" modified="2010-01-19" version="1">MRFPALNSLYGRIFTIFWLTLLVVVIAVLLLPNLDPRAQHTIPTSHLKRLQQMAHNIGEEIDQSPISLPRTLKELTSHEKHRSAQLYFTTEDGEILAPLKRNRALRNFITIADNPKSPRQRLYGRWMMAGPFVVQTQQQNLLLYVGRVWREPPPFFIQILDKPFQLLLATMIVSTPFLLWLAWVVSRPAYRLQQAAERVAKGEFEVDPKLEQGPREFKQAGASFNQMVGALNHMISGQQRLLSDISHELRSPLTRLRMATALATRKQGSSKELDRIDTEAERLEKMIGELLELSRMQVNSHQERQHFDAHSLWFEMLEDARFEAEQNHKQLTYNQLEDWPICGNPNLLISALENIIRNAIKYGNDQIEIHFHQQHNQLIITVDDNGEGVPEEELNDIFRPFYRVSTARDRSSGGTGLGLAITESALRQHSGSAQASRSPLGGLRITLQLPLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1H3</accession>
    <name>D0Z1H3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cell division protein ftsN</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_003387</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003387"/>
    <dbReference type="EnsemblBacteria" id="EEZ42354">
        <property type="protein sequence ID" value="EEZ42354"/>
        <property type="gene ID" value="VDA_003387"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3087">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042834">
        <property type="term" value="F:peptidoglycan binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011930">
        <property type="entry name" value="FtsN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007730">
        <property type="entry name" value="SPOR-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036680">
        <property type="entry name" value="SPOR-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05036">
        <property type="entry name" value="SPOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110997">
        <property type="entry name" value="SSF110997"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02223">
        <property type="entry name" value="ftsN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51724">
        <property type="entry name" value="SPOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="SPOR" evidence="3">
        <location>
            <begin position="196"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ42354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="276" mass="30707" checksum="2625F749BFA9F3C3" modified="2010-01-19" version="1">MQKKAPTRQSRKAPTTVADRFPKKLGALALVLTGLLGYGLFYLSHSPAPEDKTPEASVTKEQKQLDQLIEKVQQTEQKKDQLPPKPEEKWRYIKELENKVIQLPTQDEKQRLAAEKAQADRARIAAEKAARDKAEAERRKQQQEATQKSDAAKPTVSPATDKVADVAKPKPVQPTTPVVPTEPVKPQPKPETKPVTKPSVRYIVQCGAYHSADQANERKATIAFQGFNSQVSMVKTSSGTWHKVYIGPYPDRDQALKARGRLQSSGIEPCAILSWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1K3</accession>
    <name>D0Z1K3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Para-aminobenzoate synthase amidotransferase component</fullName>
            <ecNumber evidence="2">2.6.1.85</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003417</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.6.1.85" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302671.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003417"/>
    <dbReference type="EnsemblBacteria" id="EEZ42384">
        <property type="protein sequence ID" value="EEZ42384"/>
        <property type="gene ID" value="VDA_003417"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0512">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1561172at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046820">
        <property type="term" value="F:4-amino-4-deoxychorismate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071704">
        <property type="term" value="P:organic substance metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd01743">
        <property type="entry name" value="GATase1_Anthranilate_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006221">
        <property type="entry name" value="TrpG/PapA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00566">
        <property type="entry name" value="trpG_papA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GATase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="194" mass="21237" checksum="6622CC95EEAE9A62" modified="2010-01-19" version="1">MLLIIDNYDSFTYNLYQYFCQLGAEVKVVRNDEIDIAGIEALNPTHLVISPGPCTPNEAGISLAAIQHFAGKLPILGVCLGHQAMAQAFGATIVRAKQAMHGKTSPITHTGQSVFHGLNNPLTVTRYHSLVVQADTLPSEFMVTAWTTTSDGKRDEIMGICHKELALEGVQFHPESILTEQGHQLLANFLRRKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1P5</accession>
    <name>D0Z1P5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9 10">Protein translocase subunit SecY</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">secY</name>
        <name evidence="13" type="ORF">VDA_003459</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 11">Membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 12">Belongs to the SecY/SEC61-alpha family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302827.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003459"/>
    <dbReference type="EnsemblBacteria" id="EEZ42426">
        <property type="protein sequence ID" value="EEZ42426"/>
        <property type="gene ID" value="VDA_003459"/>
    </dbReference>
    <dbReference type="GeneID" id="57340084"/>
    <dbReference type="eggNOG" id="COG0201">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1567535at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043952">
        <property type="term" value="P:protein transport by the Sec complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01465">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026593">
        <property type="entry name" value="SecY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002208">
        <property type="entry name" value="SecY/SEC61-alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030659">
        <property type="entry name" value="SecY_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023201">
        <property type="entry name" value="SecY_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10906">
        <property type="entry name" value="PTHR10906"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00344">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004557">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103491">
        <property type="entry name" value="SSF103491"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00967">
        <property type="entry name" value="3a0501s007"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00755">
        <property type="entry name" value="SECY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00756">
        <property type="entry name" value="SECY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9 11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9 11" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="75"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="119"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="152"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="184"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="213"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="272"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="313"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="371"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="397"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ42426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="441" mass="48155" checksum="943A1C989E33566A" modified="2010-01-19" version="1">MAKQPGQDFRSAKGGLAELKSRLFFVLGAILIFRAGSFVPIPGIDAAVLADLFEQQKGTIIELFNMFSGGALSRASILALGIMPYISASIIVQLLTVVHPALAELKKEGEAGRRKISQYTRYGTLVLATFQAIGIATGLPSMIPGLVVNPGLGFYFVAVVSLVTGTMFLMWLGEQITERGIGNGISLIIFTGIVAGLPPAIGQTVEQARQGELHVLLLLLIAVISFAVIYFVVFMERGQRRIVVNYAKRQQGRRVFAAQSTHLPLKINMAGVIPAIFASSIILFPGTLAQWFGQSENLGWLSDISLALSPGQPLYVMLYAAAIIFFCFFYTALVFNPRETADNLKKSGAFVPGIRPGEQTAKYIDKVMTRLTLAGALYITFICLIPEFMMIAWNVRFYFGGTSLLIVVVVIMDFMAQVQTHLMSQQYESVLKKANLKGYGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1P6</accession>
    <name>D0Z1P6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L36</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpmJ</name>
        <name evidence="6" type="ORF">VDA_003460</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the bacterial ribosomal protein bL36 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_000868186.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="SMR" id="D0Z1P6"/>
    <dbReference type="STRING" id="675817.VDA_003460"/>
    <dbReference type="EnsemblBacteria" id="EEZ42427">
        <property type="protein sequence ID" value="EEZ42427"/>
        <property type="gene ID" value="VDA_003460"/>
    </dbReference>
    <dbReference type="GeneID" id="62576190"/>
    <dbReference type="GeneID" id="67378607"/>
    <dbReference type="eggNOG" id="COG0257">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2066169at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00251">
        <property type="entry name" value="Ribosomal_L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000473">
        <property type="entry name" value="Ribosomal_L36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035977">
        <property type="entry name" value="Ribosomal_L36_sp"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42888">
        <property type="entry name" value="PTHR42888"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00444">
        <property type="entry name" value="Ribosomal_L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57840">
        <property type="entry name" value="SSF57840"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01022">
        <property type="entry name" value="rpmJ_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00828">
        <property type="entry name" value="RIBOSOMAL_L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ42427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="37" mass="4278" checksum="52E753A5DC1644ED" modified="2010-01-19" version="1">MKVRASVKKICRNCKVIKRNGVVRVICSEPKHKQRQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1W2</accession>
    <name>D0Z1W2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein yrbA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_003526</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the BolA/IbaG family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303697.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003526"/>
    <dbReference type="EnsemblBacteria" id="EEZ42493">
        <property type="protein sequence ID" value="EEZ42493"/>
        <property type="gene ID" value="VDA_003526"/>
    </dbReference>
    <dbReference type="GeneID" id="57339997"/>
    <dbReference type="eggNOG" id="COG5007">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2009812at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002634">
        <property type="entry name" value="BolA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036065">
        <property type="entry name" value="BolA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01722">
        <property type="entry name" value="BolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003113">
        <property type="entry name" value="BolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82657">
        <property type="entry name" value="SSF82657"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ42493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="84" mass="9341" checksum="D1FA7AA6B13AEFAA" modified="2010-01-19" version="1">MEISEIKAILESALELDEVIVKGEGSHYEVIAVGAIFDGMSRVKKQQTIYGPLMGHIAANDIHALSIKTFTPQEWARDRKLMSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z217</accession>
    <name>D0Z217_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted hydrolase of the metallo-beta-lactamase superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_001866</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001866"/>
    <dbReference type="EnsemblBacteria" id="EEZ40834">
        <property type="protein sequence ID" value="EEZ40834"/>
        <property type="gene ID" value="VDA_001866"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0658">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2333">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030420">
        <property type="term" value="P:establishment of competence for transformation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07731">
        <property type="entry name" value="ComA-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035681">
        <property type="entry name" value="ComA-like_MBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004477">
        <property type="entry name" value="ComEC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004797">
        <property type="entry name" value="Competence_ComEC/Rec2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03772">
        <property type="entry name" value="Competence"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00360">
        <property type="entry name" value="ComEC_N-term"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00361">
        <property type="entry name" value="ComEC_Rec2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="18"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="41"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="247"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="281"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="324"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="349"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="388"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="417"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="452"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="484"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="505"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="domain" description="Lactamase_B" evidence="7">
        <location>
            <begin position="541"/>
            <end position="727"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ40834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="787" mass="90244" checksum="22970A1B7E53D07C" modified="2010-01-19" version="1">MIICRGILALSCLKSRPMFLFCTAVVFGILSLHIWDVLPNMQWLILVSFVTTSIALIFRYYWLLWFTLSASWALLYAHQYMNELESIPQKRSHHTIEVRVNSLINRNISSDSIEVSPTINTLSSYVLPSTFKLSWDQSSWVKQGQKWQIPVQFSRPYGMLNEAGFDSEVHAVGKGITRKGRVIYQADNLPMMLDSSVTYRQQFFDYISSYLVDLKHHAYLYALTFGYRNGLTADDWLILRDSGLAHLMAISGLHIGLAMLWGWGIGWFLRSLLPQNQKFLWLPLTCGFSFALAYAWLAGFSLPTQRALLMCLIAGGLLYARRTWLSWQIFLVTLTLCLVWNPLSSYASGFWLSFSAVWILFASRVFSGKSLSSPKTARHSKFSHKAKSNAVELVKLQFVLLIFMLPLQWHWFGGMSIWAPIINFIAVPWVSMVTVPLLFLAILTSWWLPASLLIWQLADWSLLPVLYIASWAKGGWWLFSENTYWILCGAIVWGISLYLLPLRQFIGGHISIFVLLCLFYWNLNNRSPAMGWKVHMLDVGHGLAILIEKNQQAWLYDTGSQWKDSSIARRVIAPVLAKKGIGQLDGFIISHSDNDHAGGTDHIVADFNPVKRRSSDNRSGFSVCKQGESWLWQGLKFEVLWPPVIRDYASNPYSCVISIRESGRKLSQTQILLTGDIDDVVELLLAKAYPQLTTEVLVVPHHGSATSSTYTWLDKLQPSYALASINLYNPWRLPSQRIKERYEQRNIVWLTTANEGQISVQFVDNQIKLQRYRQDVATEWFRWQRDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z262</accession>
    <name>D0Z262_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Lipid A biosynthesis lauroyltransferase</fullName>
            <ecNumber evidence="8">2.3.1.241</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Kdo(2)-lipid IV(A) lauroyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">lpxL</name>
        <name evidence="9" type="ORF">VDA_001930</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>alpha-Kdo-(2-&gt;4)-alpha-Kdo-(2-&gt;6)-lipid IVA + dodecanoyl-[ACP] = dodecanoyl-(Kdo)2-lipid IVA + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:28442"/>
            <dbReference type="Rhea" id="RHEA-COMP:9644"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="ChEBI" id="CHEBI:60365"/>
            <dbReference type="ChEBI" id="CHEBI:61524"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:65264"/>
            <dbReference type="EC" id="2.3.1.241"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Bacterial outer membrane biogenesis; lipopolysaccharide biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8">Glycolipid biosynthesis; KDO(2)-lipid A biosynthesis; KDO(2)-lipid A from CMP-3-deoxy-D-manno-octulosonate and lipid IV(A): step 3/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell inner membrane</location>
            <topology evidence="8">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the LpxL/LpxM/LpxP family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.241" evidence="8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298957.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001930"/>
    <dbReference type="EnsemblBacteria" id="EEZ40898">
        <property type="protein sequence ID" value="EEZ40898"/>
        <property type="gene ID" value="VDA_001930"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1560">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1106624at2"/>
    <dbReference type="UniPathway" id="UPA00030"/>
    <dbReference type="UniPathway" id="UPA00360">
        <property type="reaction ID" value="UER00485"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008913">
        <property type="term" value="F:lauroyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036104">
        <property type="term" value="P:Kdo2-lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009103">
        <property type="term" value="P:lipopolysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd07984">
        <property type="entry name" value="LPLAT_LABLAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01942">
        <property type="entry name" value="Lipid_A_LpxL_LpxP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004960">
        <property type="entry name" value="LipA_acyltrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011920">
        <property type="entry name" value="Lipid_A_LpxL_LpxP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30606">
        <property type="entry name" value="PTHR30606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03279">
        <property type="entry name" value="Lip_A_acyltrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF026649">
        <property type="entry name" value="MsbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02207">
        <property type="entry name" value="lipid_A_htrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2 8" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0448">Lipopolysaccharide biosynthesis</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="18"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="HXXXXD motif" evidence="8">
        <location>
            <begin position="134"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ40898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="310" mass="35937" checksum="9A070FA48ACB7FB0" modified="2010-01-19" version="1">MTKYNAPSFSLSLLHPRYWGTLCLVAVMYSLSWLPYFMQYHLGRWIGRIAIKLMPKRRQTIRRNLELCFPDMDTNEREELIKQNIDNSGLALFETGMAWFWPDLRVERHVDIEGLEYLEQLERDGKGALMLAVHSMNLELGARAFGIQMSGMGVYRPNNNPCFDYFQYKGRARSNRSLIDRKNVRCMLDSLNSGARVWYAPDHDYGMKRSAFAPLFAVENACTTTGTSLLVDNSDCAIVPFTIVRLNQSGQYKLTIHKPLIDQFPKENPVEGAKFVNKIVEQSILTEPSQYMWLHRRFKTRPENEASLYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2B0</accession>
    <name>D0Z2B0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Metal-dependent phosphohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000561</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304725.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000561"/>
    <dbReference type="EnsemblBacteria" id="EEZ39541">
        <property type="protein sequence ID" value="EEZ39541"/>
        <property type="gene ID" value="VDA_000561"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1418">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1798994at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD" evidence="1">
        <location>
            <begin position="25"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="209" mass="23753" checksum="CD06F518A1634EA5" modified="2010-01-19" version="1">MDCLAFEVDLVEYLKSEMSQDMAHDVDHILRVVKSAKMLCQQEGANIAIVLPAAYLHDCFSYPKDHPDRHLSSYKAADKAVEFLNSIGYPSEYFEAIHHAIVAHSFSAQVTPTTLEAQIVQDADRLDALGAIGVTRCILVSAKLKRPLYQLDDPFCQQRSPDDSQYTLDHFYTKLLKLTDTMNTRSAQEEAGRRTEFMYAYLKQLELEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2B2</accession>
    <name>D0Z2B2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Beta-ketoadipate enol-lactone hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.24</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000563</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.1.24" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304727.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000563"/>
    <dbReference type="EnsemblBacteria" id="EEZ39543">
        <property type="protein sequence ID" value="EEZ39543"/>
        <property type="gene ID" value="VDA_000563"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1196738at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047570">
        <property type="term" value="F:3-oxoadipate enol-lactonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="24"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="270" mass="30102" checksum="2D0DCF1F676EDFA2" modified="2010-01-19" version="1">MQTFSVGSQTMTYLDQGTGPVIVFGHSYLWDHKMWQPQIDVLSQHYRCIVPDLWAHGGSDAAPSSTNTLRDYADDVLALLDHLKIDKFAIVGLSVGGMWGAELAIKAQGRVQALVMMDTFIGYEPEVTCAKYFQMLDTIAELKMVPPPMIDVVTPMFFARNGEQQNPELVSAFRSSLAALQGDKAQAVARVGKMVFGRRDTFDDIEHLQLPTLIMVGMEDMPRPPLEAQLMHDAIKDSEYVVIPQAGHISNLEQPELVTEKLQQFLAKHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2F2</accession>
    <name>D0Z2F2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator MerR family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000603</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304841.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000603"/>
    <dbReference type="EnsemblBacteria" id="EEZ39583">
        <property type="protein sequence ID" value="EEZ39583"/>
        <property type="gene ID" value="VDA_000603"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0789">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1467120at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13411">
        <property type="entry name" value="MerR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00552">
        <property type="entry name" value="HTH_MERR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH merR-type" evidence="1">
        <location>
            <begin position="10"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="273" mass="30884" checksum="A82475346286612E" modified="2010-01-19" version="1">MTEINQTEKRYAIGEVSEITGVNSVTLRAWQRRYGLIVPQRTPKGHRLYTHDDIVKIRQIVSWLKKGVSIGKVKPLLETQGQAREQATTEFHHELIDSMMAEVEKLDGHKLSKILLENMKIYPFDMLVNQVLMPIHCRIADTNNPLKGIQSAFWQGVITRCCNEVMVKAVKPKAPRCLLLSFEQSELIWIKALLLTYQGYAVTTLVSISDKLTGFQDALTALPWKACVVVGENKLTTPQLQELIAVNQAFAFPMILADSLRVIHANDFKTSEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-12-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2J5</accession>
    <name>D0Z2J5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000646</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304952.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000646"/>
    <dbReference type="EnsemblBacteria" id="EEZ39626">
        <property type="protein sequence ID" value="EEZ39626"/>
        <property type="gene ID" value="VDA_000646"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1042">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1247">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="445933at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043758">
        <property type="term" value="F:acetate-CoA ligase (ADP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.261">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003781">
        <property type="entry name" value="CoA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043938">
        <property type="entry name" value="Ligase_CoA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032875">
        <property type="entry name" value="Succ_CoA_lig_flav_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13380">
        <property type="entry name" value="CoA_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19045">
        <property type="entry name" value="Ligase_CoA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13607">
        <property type="entry name" value="Succ_CoA_lig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00881">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52210">
        <property type="entry name" value="SSF52210"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="743"/>
            <end position="898"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="899" mass="99309" checksum="3A30E25844CB18B8" modified="2010-01-19" version="1">MATTPLSALLNPKSIAVIGASNQTHRTGFVIINNLLQSHFNGPIFPVTPKYDSVAGILAYPTISDLPRTPDIAIVCTHASKTVKIIKELGEKGVKSAVILAAGTSTLKDETGTTVADYLQQLAKRYQIRLLGPNSMGIILPWLNLNASFAPTPANKGNIAFISQSAAVCTTILDWARNKNIGFSTFISLGDGLDINFAELLDALSQDGKTEAILLYLDSVNNAREFLSAARAAARNRRILVVKGGRTLAGSEAVKHHTGSNLGADIVYEAAIRRAGLLRVKNTHELFAAVETLAHSVPLRGERLAIITNGGGPAIMAVDSLSERGGKLAQLSSTTLHQLKKQLPNYWPASNPIDLLGDATIERYEHTINTLLDSDEADALLIMHTPSAIAPSQQTAERLVQTLKQHPNIKKFNVLSNWTGEYEGQVARDIFAQAGFPAYRTPESAVSAFMYLVEYRRNQKLLRETPKTLEPISTSNDNFSPQQAQAIIQELLNHNITQLETHEVQPILKGYGFKTLPTWLANDAVEAIHIAEQIGYPVAVKLRSPDIEYKSEVHGVMLHLRDAQEVESAAQAMLERVNIDYPTAQIDGLLVQRMANRAGAQELRVAVRNDPIFGPVIFLGEELMNWNCYQDSAVGLPPLNMALARYMIIDALKSQKIKQRSTLVPIDIDALCSFLVTVSQIIIDCPNIESLDIHPLLANGPELTIIDASMTLNADTNQIPRLAIRPYPKELEQWVELKSGKTILLRPILPEDEPEHKSFISHVTQEDLYKRFFSDVGEFNHEAMSNFTQIDYDREMAFIAVFENKGHTEILGVVRALSDPDNMDAEFAILIRSDLKGLGLGRIMMEKIIHYCQHKGLQRITGMTMPNNRSMIMLAQKMGFHVDIQMEDGVVEMELNLIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2N4</accession>
    <name>D0Z2N4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Multidrug resistance efflux pump</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000685</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305055.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000685"/>
    <dbReference type="EnsemblBacteria" id="EEZ39665">
        <property type="protein sequence ID" value="EEZ39665"/>
        <property type="gene ID" value="VDA_000685"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1566">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="757027at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039562">
        <property type="entry name" value="MFP_biotin_lipoyl_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13533">
        <property type="entry name" value="Biotin_lipoyl_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin_lipoyl_2" evidence="2">
        <location>
            <begin position="45"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="106"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="355" mass="39513" checksum="9830D019A759DCA3" modified="2010-01-19" version="1">MQTAESAFRRWMRCLIILFLIFLAYIIVADRHAPLTTESRVHGYVVQIAPEVSGNVTSVKVKNNQDVKKGELLFTIDDSKYQIAVERAKVNLAQAHEQETALYAQADAARAQIATAQAAYNNANREYNRIQKLANKNLVSQSMRDNAFAQDKVTRSNLAAAKQQLLVIQAKLGSTPGDSTMVHAAENALKQAELDLSHTQVKAPSNGVITNMQLDEGTMASANKPILTFIPTDNMWVSADFREKATALINDKSAAYVTYDALPGEVFDFKIASRDFGVSSAQQNPNGQLTTVEVNNRWVRDAQRIRVNLVSEEPMPKQLFVGSRATVVIYPTENPIWQFMASAEIWIASVFHYIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z358</accession>
    <name>D0Z358_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative GTPase (G3E family)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000859</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305551.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000859"/>
    <dbReference type="EnsemblBacteria" id="EEZ39839">
        <property type="protein sequence ID" value="EEZ39839"/>
        <property type="gene ID" value="VDA_000859"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0523">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1267701at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003495">
        <property type="entry name" value="CobW/HypB/UreG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02492">
        <property type="entry name" value="cobW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="cobW" evidence="1">
        <location>
            <begin position="5"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="329" mass="36672" checksum="706ED4E0B012D736" modified="2010-01-19" version="1">MKRIPTNIITGFLGAGKTTAILSLLARKPENEKWAVLINEFGNVGVDGAMMEQQGAIIKEVPGGCMCCVAGLPMSVGINALLAQKPDRLLLEPTGLGHPKEVINKLTSDTYKNYIDLRATITLVDPRHFSESIYTENENFQDQLALADIVVANKIDQCDDYDLFLFEETLAKAEPQKALLAHVENGKLDPAWLDVERLQREASHSHHHHHNDDNAELAPLPEFELAPGQQFIRKENQGQGYHSCGWFFAAEQLFDFSKLFSLLSNINAERVKAVVNTDKGCYAFNVVNRIVTVNELSLEGFESRLEVIDKEILPWDELENILCSIVTAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z359</accession>
    <name>D0Z359_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative TldD protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_000860</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase U62 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305553.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000860"/>
    <dbReference type="EnsemblBacteria" id="EEZ39840">
        <property type="protein sequence ID" value="EEZ39840"/>
        <property type="gene ID" value="VDA_000860"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0312">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="806701at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045569">
        <property type="entry name" value="Metalloprtase-TldD/E_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045570">
        <property type="entry name" value="Metalloprtase-TldD/E_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002510">
        <property type="entry name" value="Metalloprtase-TldD/E_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025502">
        <property type="entry name" value="TldD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035068">
        <property type="entry name" value="TldD/PmbA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036059">
        <property type="entry name" value="TldD/PmbA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01523">
        <property type="entry name" value="PmbA_TldD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19289">
        <property type="entry name" value="PmbA_TldD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19290">
        <property type="entry name" value="PmbA_TldD_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004919">
        <property type="entry name" value="TldD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111283">
        <property type="entry name" value="SSF111283"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PmbA_TldD" evidence="3">
        <location>
            <begin position="22"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="PmbA_TldD_M" evidence="5">
        <location>
            <begin position="115"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="PmbA_TldD_C" evidence="4">
        <location>
            <begin position="227"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF19289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF19290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ39840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="461" mass="49707" checksum="28D9B4D1D9373786" modified="2010-01-19" version="1">MLNSTTAKAVIDHALFLGADFAELFVEHHQSSSVQLISGDIDRVNSGIDFGIGIRLFFGLKVLYGYTNSTDEEELKRVTSLLAAKDKRERIVAPISFDLRRYESRHHCELPLSGDPNLAEKIAFLRKIDNAARNEHEKISQLVAGIGSREQKVEIFNSEGLHINDIRHYTRLSANAIAQNGTEQSSGYEAPGALTGWEFHHKVDPEQLGQDVAKQAMVKLFADACPSGEMPVIIGNGFGGVIFHEACGHLLETTSVAKKASVFHDKMGEMIANSAVNAVDDGTLVNEWGSINIDDEGVETQRTQLIKEGQLTGFMVDKMGGLKTGYASTGSGRRESYKYAPTSRMRNTFIEPGNSSLDEMLAGVERGIYAKKMGGGSVQPGTGEFNFSVQEAYLIENGKITKPLKSATLISTGPKVLKEISMVGSDFELAAGMCGSVSGSVPTTVGQATLKVDNILVGGGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3A2</accession>
    <name>D0Z3A2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000903</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305680.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39883">
        <property type="protein sequence ID" value="EEZ39883"/>
        <property type="gene ID" value="VDA_000903"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502ZS9M">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1788014at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="236" mass="25717" checksum="69B1D63EDF61DE30" modified="2010-01-19" version="1">MSDSINNTNPYEAYYKAMMDMQMEMTKIYMANMQNGEVPPMPPFHNFPPFPHPGLCHPFQMPPVMGAHPYHGMLPPNHWHQPGMMQPTQESQSPEPSEDHPLYVQAQAMLDGALGEDAGTFKEILGSFGMNDKEFWKGAMVGAAAALLLSNENVRGKLMGLVSGAGSMLKSGGESVKEGAMNTASTVKENVSTGSEIFKETYAAGKQGFQESVERHKTESAPTSDDSSQPDVKTNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3A6</accession>
    <name>D0Z3A6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transaldolase</fullName>
            <ecNumber evidence="3">2.2.1.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000907</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.2.1.2" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305688.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000907"/>
    <dbReference type="EnsemblBacteria" id="EEZ39887">
        <property type="protein sequence ID" value="EEZ39887"/>
        <property type="gene ID" value="VDA_000907"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0176">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="784333at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016832">
        <property type="term" value="F:aldehyde-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004801">
        <property type="term" value="F:transaldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00956">
        <property type="entry name" value="Transaldolase_FSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001585">
        <property type="entry name" value="TAL/FSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018225">
        <property type="entry name" value="Transaldolase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033919">
        <property type="entry name" value="TSA/FSA_arc/bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10683">
        <property type="entry name" value="PTHR10683"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00923">
        <property type="entry name" value="TAL_FSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01054">
        <property type="entry name" value="TRANSALDOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0704">Schiff base</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="224" mass="24149" checksum="F85AF838A7CE57BA" modified="2010-01-19" version="1">MIELYLDTADVAEVKRFNQCLPLKGVTTNPSILAKSKQGLNETLASMQEALGGTPRFHAQVISSTVNGMVDEARQLNELPYDMVVKVPATETGLSAIKLMKKEGITVLATAIYSAQQGFLAALCGADYLAPYVNRIDAINGNGVEVVADLQLLLDQNKLSSKILAASFKNTQQAMEVMKIGIEAITLPTDVAAQMFAHPAVKPAVEQFDVDWKGVFGDKLSFES</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3C5</accession>
    <name>D0Z3C5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000926</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305738.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39906">
        <property type="protein sequence ID" value="EEZ39906"/>
        <property type="gene ID" value="VDA_000926"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031HUM">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038500">
        <property type="entry name" value="Antitermination_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013464">
        <property type="entry name" value="CHP02642"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036410">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57938">
        <property type="entry name" value="SSF57938"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02642">
        <property type="entry name" value="phage_xxxx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="266" mass="30317" checksum="BA58825FEF335B39" modified="2010-01-19" version="1">MSRAVELLARMHEVRSITADEHGRQTITGDVIIAVFGRVQHEMPFGMDLLMAKYVHDAQAFNRLVDRITVSVQGEPLKRKDLAIALGCVALDVFCDKPVASQQRQLTSLWRKYSTQAKRSHKLVKRWECQLKNIERELDYCETISAEDRINARISNIESLIIKERRRLDEFAQSQGLSKSICPRCSGTGFTQTTQCPSCDGKGSFTPTLDNIRQHLRHIGLARVSDKLWDGELKPWFDKCLTMMHREAGEATCELTNQLNKEKSIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3E1</accession>
    <name>D0Z3E1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MoxR-like ATPase in aerotolerance operon</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000942</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305788.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000942"/>
    <dbReference type="EnsemblBacteria" id="EEZ39922">
        <property type="protein sequence ID" value="EEZ39922"/>
        <property type="gene ID" value="VDA_000942"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0714">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="688156at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011703">
        <property type="entry name" value="ATPase_AAA-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041628">
        <property type="entry name" value="ChlI/MoxR_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07726">
        <property type="entry name" value="AAA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17863">
        <property type="entry name" value="AAA_lid_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_3" evidence="1">
        <location>
            <begin position="36"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="domain" description="AAA_lid_2" evidence="2">
        <location>
            <begin position="246"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="318" mass="35570" checksum="1CAB7E48CED041E9" modified="2010-01-19" version="1">MLNNRFQKINNYLKSQVIGQPELVEQLLIALLADGHILVEGPPGLAKTRAVKVLSDCIEGKFHRIQFTPDLLPADLTGTDIFRPETGEFSFQAGPIFNSLILADEINRAPAKVQAAMLEAMAEKQITAGRKTYPLPELFLVMATQNPIEQEGTYPLPEAQLDRFLLQLMVDYPNADSELEILRLNRGEALGNKVAEAVTISQEEIFEARKQVLTIHMAEDVEQYIIRIVMATRQPEKYSGTLASWLQMGVSPRATLALDRCARAHAWLQGRDFVTPEDVQTMAFPVLRHRLLLSYEAQAEGIASDRVIEHLLEQVASV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3K0</accession>
    <name>D0Z3K0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Endopeptidase La</fullName>
            <ecNumber evidence="1">3.4.21.53</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001001</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of proteins in presence of ATP.</text>
            <dbReference type="EC" id="3.4.21.53"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S16 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.53" evidence="1"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305954.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001001"/>
    <dbReference type="EnsemblBacteria" id="EEZ39981">
        <property type="protein sequence ID" value="EEZ39981"/>
        <property type="gene ID" value="VDA_001001"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1067">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="128102at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041699">
        <property type="entry name" value="AAA_32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008269">
        <property type="entry name" value="Lon_proteolytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027065">
        <property type="entry name" value="Lon_Prtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10046">
        <property type="entry name" value="PTHR10046"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13654">
        <property type="entry name" value="AAA_32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05362">
        <property type="entry name" value="Lon_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51786">
        <property type="entry name" value="LON_PROTEOLYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Lon proteolytic" evidence="3">
        <location>
            <begin position="566"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="138"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="656"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="699"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="790" mass="88691" checksum="4C30FDA48B4AD2AD" modified="2010-01-19" version="1">MSVQPLSSDKLYRESELNGLAKEIKSTKQLAPIDEIVGQERAQRAVEFAMSIKEKGYNIYAIGRNGLGKRTMVLRYLNRHDPNGNGHTLYDWCYVSNFDNSRSPKVLKLPAGSGLPFKKDIEQLMKRLVKSLPLAFDNEMYYSRADKLKQQLAEKQGEILQAISSQAQVNNISVTVTAQGEYQMVAMNGEQPHTEESFQALSEQEQNHFEQVINALEAELRGMIRQFTEFEEAFSDKLQKLDEEVAQEVVSHVLKPLKIQYGKISEAKHYLTALQKDILENLDIFLEDNEEQLALAYASLDKKMPRRYQINVLVAQDEHAFPIVVEESPTYHNLFGYIENATFKGTVFTDYSLIRPGSLHRANGGVLLMDAVKVLERPYVWDGLKRALRARELNLNSLEREVTLSGVVSLEPEAIPLDVKIILFGDYQTYQLLQHYDPEFGELFRVTADFEDDMPRTEQSEEQYAKFIASIIQDNNMLHCDRKAIARIIEYSSRRADDQNKLSLHSADIANLLRETNYCAKSSNANMIRSHHVEQALANQIQRVSRLQDMVKQGFVNGTTLIDVTGERIGQVNALSVLTTTDHQFGSASRITATTAYGSGEIFDIERTVDLGGSIHSKGVMILSAYLASVFGKTARIPLSTHITFEQSYGGVDGDSASMAELCAIVSAYSQQPLRQDVAITGSMNQFGEAQPIGGVNEKIEGFFDVCAIKGRTSQQGVIIPQSNVHNLMLRKDIVEAVEKGEFHILAINHVTEAIEILMKIPAGIWHDSTGYDANTLYGMAQIRLNTLKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3P9</accession>
    <name>D0Z3P9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transporter AcrB/D/F family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001050</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306085.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001050"/>
    <dbReference type="EnsemblBacteria" id="EEZ40030">
        <property type="protein sequence ID" value="EEZ40030"/>
        <property type="gene ID" value="VDA_001050"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0841">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="38744at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="338"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="363"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="394"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="438"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="468"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="516"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="858"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="884"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="910"/>
            <end position="931"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="959"/>
            <end position="979"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="985"/>
            <end position="1008"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="1016" mass="111343" checksum="9BA4B3042BD8EBF6" modified="2010-01-19" version="1">MDIARYTIAKRTSVWVLIALTLIGGYISYLKLGRFEDPEFVIRQAVINTPYSGATAQEVSDEVTDVIEGAVQSLQELKEVKSVSKQGMSEVTVEIKLEFAKSSADLQQVWDKLRRKVNDAQRQLPPGAGPSIVNDDFSDVYALFFAVTGDGFTDKQLQDYVDSLRRELVLVPGVAKTATLAEQQETIFVEISSERLAQFGLSAEKVFQVLQKQNLVTVAGSIETDSMRIPVIPSSSIRSFNDLKNLQVGVGENNTVLRLGDIATVKRGYKEPSSMLMRYNGERAIGFGISNVTGGNVVDMGDAVKARIAELEGQRPLGMELHVISMQSDSVRDSVTNFIDNLIAAVVIVFIVLLVFMGLRSGIIIGFVLLLTVAGTLCIMLIEDIAMQRISLGALIIALGMLVDNAIVVTDGVLVRLQNNPEEDRATIVSDIVNSTKWPLLGGTVVGICAFSAIGLSPSDMGEYAGSLFWVILYSMFLSWVFAVTVTPMLCYDFLKVKPKVPGSKPSKMVTGYKTVLTWVLAHRAMSTTLLLVMLGVAVYAVRFVPPGFMPESQRPQFVVDVYLPQGSDIKRTEKLVAQIEQDVKVKEGITNITSFIGGGGLRFMLTYAPEARNPSYGQLLIDIDDYTKIAPLLGKLQSELDAKYPDASIKVWKFMLGRGGGKKIEAGFKGPDSKVLRQLAEQAKAIMLNDPQLIAVQDDWRQQVPVLRPVYSAEEAQRFGLTTQEINQAIAQTLSGRNVGVYREGDDLIPIVVRAPQSERDHQRAIENTEVYSHTVGGFIPVSQLVESVDVVWEDAILRRIDRMPTLLVQADPAPGVLTADAFNNVKDKIEAIELPPGYQLTWYGEYKASKDANEGLAISAPYGFAAMILSVIFMFNAIRQPLVIWLTAPLALIGVTIGLIIFQTPFEFMAILGFLSLIGMMVKNAIVLVDQADAEILEGKAPYQAIIDAAISRARPVLLGAFTTILGVAPLLIDPFFKSMAVTIMFGLLFATLLTLLVIPLFYAMFFRVKVETA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3Q9</accession>
    <name>D0Z3Q9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Tagatose-bisphosphate aldolase</fullName>
            <ecNumber evidence="2">4.1.2.40</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">D-tagatose-bisphosphate aldolase class II</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Tagatose-bisphosphate aldolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_001060</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8">Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate metabolism; D-tagatose 6-phosphate degradation; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-tagatose 6-phosphate: step 2/2.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.40" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306113.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001060"/>
    <dbReference type="EnsemblBacteria" id="EEZ40040">
        <property type="protein sequence ID" value="EEZ40040"/>
        <property type="gene ID" value="VDA_001060"/>
    </dbReference>
    <dbReference type="GeneID" id="57343470"/>
    <dbReference type="eggNOG" id="COG0191">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="827430at2"/>
    <dbReference type="UniPathway" id="UPA00704">
        <property type="reaction ID" value="UER00716"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009025">
        <property type="term" value="F:tagatose-bisphosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001059">
        <property type="term" value="P:D-tagatose 6-phosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00947">
        <property type="entry name" value="TBP_aldolase_IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000771">
        <property type="entry name" value="FBA_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011288">
        <property type="entry name" value="TagBP_ald_KbaY/GatY"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01116">
        <property type="entry name" value="F_bP_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001359">
        <property type="entry name" value="F_bP_aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00167">
        <property type="entry name" value="cbbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01858">
        <property type="entry name" value="tag_bisphos_ald"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00602">
        <property type="entry name" value="ALDOLASE_CLASS_II_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00806">
        <property type="entry name" value="ALDOLASE_CLASS_II_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Dihydroxyacetone phosphate binding" evidence="7">
        <location>
            <begin position="209"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Dihydroxyacetone phosphate binding" evidence="7">
        <location>
            <begin position="230"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="82"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>dihydroxyacetone phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00031246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00032933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001359-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001359-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001359-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ40040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="284" mass="31328" checksum="25BCBFB33FB11115" modified="2010-01-19" version="1">MFLVSSREMLHKAQMGGYAVPAFNIHNLETVQVVVETAAEMRSPVILAGTPGTFTYAGTDYLVGICKEAAKRYEMPIALHLDHHESFTDIRQKVEAGIKSAMIDGSHHSFEENIALTRQVVEFCHRWDCSVEAELGRLGGQEDDLIVDAKDALYTDPDAAVEFIRSTGIDSLAIAIGTAHGMYKEEPRLDFDRLGIIRSKTDTPLVLHGASGVPDADVRRCIELGITKVNVATELKIAFSDAVKQYFIENPNANDPRHYIIPGKNAMKQVVMDKIRVCGSEGRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3R1</accession>
    <name>D0Z3R1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">N-acetylgalactosamine 6-sulfate sulfatase (GALNS)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_001062</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="3">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfatase family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306120.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001062"/>
    <dbReference type="EnsemblBacteria" id="EEZ40042">
        <property type="protein sequence ID" value="EEZ40042"/>
        <property type="gene ID" value="VDA_001062"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3119">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1067869at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008484">
        <property type="term" value="F:sulfuric ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024607">
        <property type="entry name" value="Sulfatase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00523">
        <property type="entry name" value="SULFATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00149">
        <property type="entry name" value="SULFATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019975" evidence="4">
        <location>
            <begin position="29"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="5">
        <location>
            <begin position="35"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="3">
        <location>
            <position position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="543" mass="59893" checksum="E71D32A4EEE76A84" modified="2010-01-19" version="1">MNLSSTKKTVVASLVAAACVAAPVTTYAAKQAEQPNVLLVIMDDLGTGQLDFALDSLDKTELAKRPVPARYQGDLDKMIDAAHRAMPNVAKLAQNGVKMTNAFVAHPVCGPSRAGIFTGRYPTSFGTYSNDDALQGVPLDIKLLPALFQENGYRTANIGKWHNAKIASKDKVAEDARTRDYHDIQIPVIGKGFGPEERGFDYSYSFYASGAALWNSPAIYQNGKNIPAPGYLTHNLTNEALKFIEDSGDKPFFINLAYSVPHIPLEQASPAKYMDRFNTGNVEADKYFAAINAADEGLGQIMALLKQKGELDNTLIFFLSDNGAVHESPMPMNGMDRGFKGQMYNGGVRVPFVAAWPNHIPAGGKSDTLISALDILPTALKAAGISIPQDMKVDGQDIMPVLAGKAEQSPHKYIYWAGPGAKHYSEENDPFWYGYWKWITYESDTIPSNPNLEKLSKGSWAIRDQDWALYFYDDGSNKVKLFNDKLDPSESKDLAQKYPEKVVEMKNAFYDWIKDKPKPVAWGQDRYHVLTESAKPAPKLAQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3V6</accession>
    <name>D0Z3V6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator AraC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001109</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306246.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001109"/>
    <dbReference type="EnsemblBacteria" id="EEZ40087">
        <property type="protein sequence ID" value="EEZ40087"/>
        <property type="gene ID" value="VDA_001109"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1622875at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020449">
        <property type="entry name" value="Tscrpt_reg_HTH_AraC-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00032">
        <property type="entry name" value="HTHARAC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="1">
        <location>
            <begin position="235"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="338" mass="38652" checksum="1825CAAB3950F43A" modified="2010-01-19" version="1">MELKCHTSSKNSPLIHTGWIALLSDSEQTTLVTNSATHSEEWDVHQFRTFYRQKALTQSLNEFPFDLTNQISPLSFGEYSLRIWTAPTLLTAIKDACHYSPLLGLPIRCLFHETKNDVIDIWFINHETSSKESDMSHNETMLVISAFISMLDANASTNIDFDLFIPKWQSSLDIKKQTEKYAHCRIHEGYPIHRLVIKKQQLDVGSSYANNAIYQQMGQLLDTELAGLKKTNITQQVYSTLDTLPSLYEASGEHIAKVMNISFRTLNRRLAEVETSYRGVLEKYKLEKALVWLENSNISMTEVASRLGFSDLSTFSRAFKRWTGVCPSQLSNHPYLIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3Y5</accession>
    <name>D0Z3Y5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">tRNA(Met) cytidine acetyltransferase TmcA</fullName>
            <ecNumber evidence="9">2.3.1.193</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">tmcA</name>
        <name evidence="12" type="ORF">VDA_001138</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>acetyl-CoA + ATP + cytidine(34) in elongator tRNA(Met) + H2O = ADP + CoA + H(+) + N(4)-acetylcytidine(34) in elongator tRNA(Met) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:43788"/>
            <dbReference type="Rhea" id="RHEA-COMP:10693"/>
            <dbReference type="Rhea" id="RHEA-COMP:10694"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:74900"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.3.1.193"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the TmcA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.193" evidence="9"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306316.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001138"/>
    <dbReference type="EnsemblBacteria" id="EEZ40116">
        <property type="protein sequence ID" value="EEZ40116"/>
        <property type="gene ID" value="VDA_001138"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1444">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1019071at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051392">
        <property type="term" value="F:tRNA N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051391">
        <property type="term" value="P:tRNA acetylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002101">
        <property type="term" value="P:tRNA wobble cytosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01886">
        <property type="entry name" value="tRNA_acetyltr_TmcA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007807">
        <property type="entry name" value="Helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032672">
        <property type="entry name" value="TmcA/NAT10/Kre33"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038321">
        <property type="entry name" value="TmcA_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013562">
        <property type="entry name" value="TmcA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024914">
        <property type="entry name" value="tRNA_acetyltr_TmcA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10925">
        <property type="entry name" value="PTHR10925"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08351">
        <property type="entry name" value="DUF1726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13718">
        <property type="entry name" value="GNAT_acetyltr_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05127">
        <property type="entry name" value="Helicase_RecD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 9" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="3 9" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="11">
        <location>
            <begin position="180"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetyltransferase" evidence="10">
        <location>
            <begin position="379"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="164"/>
            <end position="165"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="338"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ40116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="705" mass="79425" checksum="17A7D3867E15A7F5" modified="2010-01-19" version="1">MHIQFSHYLTQLIPFLQQTNSRRLVVIQGSYEWAQPYLKLCTSYYQEPLWVGELSSNLYQGRHISYKKAKTVLGQETDCVIFDGNSDLSYEAIGAVVGTIKGGGLAILFLPNEWEEDNLAYQRLLNYIDINTVLFLSESRALFPKLPEIDDSIVHTASSVLEYGAITLDQQKGIEAIIKVMTGHRKRPLVLTADRGRGKSAALGLAAAQLLSQRKIKIVVTAPSLKAAQNIFYHAADRLGLECHLGRELSWQQSMLVYVAPDELLQQHVDCDLLFVDEAAAIPTSILERILNRYSRIVFSSTIHGYEGTGRGFAIKFKQILANKMPQFRSISLHQPVRWASNDPLEKWCFDALMLNAEMADLTQLPSHHSEIIYSLVSIDVLAKDEERFRQFVGLLINAHYQTSPNDIQLLLTHPDVLCFIASYQGRIIGCCIVLKEGGFDSALAEEVRLGQRRIKGHLLPQSIAAHIGLDAALTQGCGRIQRIAIHPNCQQQGLGLKLLETVTSHAKTLDLDYLGTSFGASSDLTQFWIKANYQFIRLGLTKDASSGVHSALAVYPLTTKSETWLESAQTLFAANLMYQRVEVFSQLEPSLLLLLWRSLKQENQASFLSLDLMNMQLSAFLRGGMGYDLVVASLEQLMMWYLSQPRFLSEQDESFFCRKVLQKRSWSELVVDYELVGQKQAEQKLRSVVQEIFLKWSTEHANIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3Z5</accession>
    <name>D0Z3Z5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001148</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306345.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001148"/>
    <dbReference type="EnsemblBacteria" id="EEZ40126">
        <property type="protein sequence ID" value="EEZ40126"/>
        <property type="gene ID" value="VDA_001148"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3608">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="632656at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007036">
        <property type="entry name" value="Aste_AspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043795">
        <property type="entry name" value="N-alpha-Ac-DABA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04952">
        <property type="entry name" value="AstE_AspA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039012">
        <property type="entry name" value="ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="352" mass="38253" checksum="D8C4F7B5F4514043" modified="2010-01-19" version="1">MVAKHISSPFEFANISIAAGTRANCELEIARLYTHSPLSVSVDILHGKHPGPVLLVNAAIHGDELNGVEVVRQVIDKIDLNKLHGTVIAVPVVNVFGFIHKSRYLPDRRDLNRCFPGSERGSIAGRMAYQYFSQVVRRATHVVDLHTAAIHRTNLPQIRANLDNEAAQAMAVAFGSPVVVDASLRDGSLRAAAEAYDIPVITFEAGEALRFDPHAIGSGVQGTLNVMKHLGMLRSSRSKKEHTPMVPKATRWVRADSDGLLRSHVALGEKVEKNQIIASINDPSGASEISVIAPQGGIVIGQQTLPLVNEGDAIFHIAFFDEPDSLVEEQVESYLDDAIEVLDDDLKYGMTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z440</accession>
    <name>D0Z440_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000296</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303973.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39278">
        <property type="protein sequence ID" value="EEZ39278"/>
        <property type="gene ID" value="VDA_000296"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502Z9Q4">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1467471at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019392" evidence="1">
        <location>
            <begin position="21"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="275" mass="30976" checksum="8A0F400F2056F72D" modified="2010-01-19" version="1">MKKKLSLLLIASCIPSIVHAENQENEGYSYFSLGMENTSYKEFYSKSNSSVSVTSPTINTGGLYSINNKWDFSIDALGTFSPNHSNEHWNNGQKNQFEYIKAMTDVLLQYKLTPQWRIVAGPTLSYQTYKRYGRDSSTESIFTGVWEEKTTDIYANVGIAYDSGNLYNNWHYYVQAKAGIPLYSQTENTATELNGVTFNTFGYRSSLSGGISYRLMKGIHLGLFTALSYEYRQEDGPKFTGVIIESNGKKQAMDATLPEAQIINFSAGIQVLWKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z454</accession>
    <name>D0Z454_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Dipeptide transport system permease protein DppC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_000310</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304007.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000310"/>
    <dbReference type="EnsemblBacteria" id="EEZ39292">
        <property type="protein sequence ID" value="EEZ39292"/>
        <property type="gene ID" value="VDA_000310"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1173">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1734230at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="5"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="69"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="100"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="183"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="228"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="63"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ39292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="265" mass="29578" checksum="FF47EFE93F6DDC0A" modified="2010-01-19" version="1">MKLQWIKLIGLILGLMAGAIIVPYFIPSIDLHLTERLQSPSLTYWFGTDWLGRDVFLRSVQALACSVRVGLSSALFTGLFALFLAVLGNSSHGLYQTVRWAIDTFLALPHILLLILLTLCFGSDANAIIWAVTLSHWPRLTQLLLQEMKTIGRSRYVLHAEQFGSSRFMALCKHGFPYISAQWVIGLILLFPHILMHIAALTFLGFGLEPSQPTLGGMLSESNRYLMLGYWWLGLLPGVLLILIVLILAKAGRAMTQQVTHYAND</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z476</accession>
    <name>D0Z476_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative ARAC-type regulatory protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_000332</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304069.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000332"/>
    <dbReference type="EnsemblBacteria" id="EEZ39314">
        <property type="protein sequence ID" value="EEZ39314"/>
        <property type="gene ID" value="VDA_000332"/>
    </dbReference>
    <dbReference type="GeneID" id="57342525"/>
    <dbReference type="eggNOG" id="COG2207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1268974at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020449">
        <property type="entry name" value="Tscrpt_reg_HTH_AraC-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00032">
        <property type="entry name" value="HTHARAC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="4">
        <location>
            <begin position="182"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="280" mass="32648" checksum="79502D1B6AADFAAA" modified="2010-01-19" version="1">MNKTFVDLLDNVITDSASVNNIWFAGDSMPPPEAGYQVNFPRLELVFKGRYENTLENHQQQVDHIALEVGDALFIPANAWNKPSWDHECSVLSLLFGKSQLGFSLVSKRENEDGFYDVVKYSVPQRTGHAVDHILNALSSLAHEKKKQPADKFMLLALLSYCKDMIETPMEDTARRSQDLFKGICIYVQENFHRNINRNTVAARFNISPNHLSRLFRQEGHMRFADYISWVRLERAKFMLKRYNFRLEEVAQRCGYHDSNYFCRVFKRKTGKTPTEYRSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z493</accession>
    <name>D0Z493_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000349</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304117.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000349"/>
    <dbReference type="EnsemblBacteria" id="EEZ39331">
        <property type="protein sequence ID" value="EEZ39331"/>
        <property type="gene ID" value="VDA_000349"/>
    </dbReference>
    <dbReference type="GeneID" id="57343271"/>
    <dbReference type="eggNOG" id="ENOG5031MWP">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1778119at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="162" mass="18043" checksum="F4F47329030376CD" modified="2010-01-19" version="1">MSDVPVTVVTKAADVLPAAESSGSVWGYVAGGAILLILAGIYGYRKINTPAFLIKQVRKRNQKEMKKHGVQNSEFMVDLDKLLDSILEYANENKLKGSDVVELIKPLNDKERVKTPKDMYQSMIYIANKVGDTELSRFYKNKSKQVKASSNLMNGLFKRAGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z495</accession>
    <name>D0Z495_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cysteine desulfurase</fullName>
            <ecNumber evidence="3">2.8.1.7</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000351</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.8.1.7" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304123.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000351"/>
    <dbReference type="EnsemblBacteria" id="EEZ39333">
        <property type="protein sequence ID" value="EEZ39333"/>
        <property type="gene ID" value="VDA_000351"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0520">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="446447at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031071">
        <property type="term" value="F:cysteine desulfurase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011340">
        <property type="entry name" value="Cys_dSase-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01976">
        <property type="entry name" value="am_tr_V_VC1184"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_5" evidence="2">
        <location>
            <begin position="31"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="413" mass="46148" checksum="9236116B10BB6AF9" modified="2010-01-19" version="1">MSSYLPLNHHNIDHTRRQFPALTHGEQTRLFFDGPGGSQQPESVINAYRNFFINGNSNLGGRFATSTQTHQIVDETREKVATLIGASSGKEIIFGANMTSLTFSLSRAISQDWQAGDEIILTDIDHAANRSPWVLAAKEKGVTVHYLPIQDDRCHLDFSSFMSLLSPKTKLLALSAASNLTGTYTDLAPFIELAKANGTLTYIDAVHYLPHQQIDVTQLDADFVAGSAYKFFGPHLGFVYGREEQLENYQPFKVAPATNNIPNCWETGTLNFEAITALSATIDYLASLGTGSNLTEQITSAYRNIYQYEQELSQYFLATLNQFPELTLIGETDKDKRTPTFALSFQHHDPNDIAAMLGKHHIFTWSGHLYAERLTASLNLDTKGGVLRVGMMHYNTKQEIDTFFRVFARCLKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4L2</accession>
    <name>D0Z4L2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PfkB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000470</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304451.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000470"/>
    <dbReference type="EnsemblBacteria" id="EEZ39450">
        <property type="protein sequence ID" value="EEZ39450"/>
        <property type="gene ID" value="VDA_000470"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0524">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1604782at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00583">
        <property type="entry name" value="PFKB_KINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00584">
        <property type="entry name" value="PFKB_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="3">
        <location>
            <begin position="13"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="318" mass="34602" checksum="57B80899D31B08B6" modified="2010-01-19" version="1">MIDILHLHPTRPVIVIGAAFGDLMLEVDQLPTSGADIEANEMGQHIGGCAFNVARALSRLSIPVINGISIGNGKWGQAIEQEMQKEHLSPLLFHPTKDNGWCIALVDKTKERTFITVNGCEQEWSPELLAKIPTPDNAIIYVSGYELVGTHAQPLQQWLLSQTNDKTLYLDLGPRINELSSEFLIQLIEKQPILTLNRDELAMLMNRIDQQEGDNVVAAHFFANQHNCQLICRFDCEGATVCEPDNIPMTEPAFQVEVADTIAAGDSHCAGVIAGLASGLSLVESTRLGNMVAAIVVSKVGSDGAPTRDELAIFAQNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4P9</accession>
    <name>D0Z4P9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aminomethyltransferase</fullName>
            <ecNumber evidence="3">2.1.2.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Glycine cleavage system T protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_000507</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(6S)-5,6,7,8-tetrahydrofolate + (R)-N(6)-(S(8)-aminomethyldihydrolipoyl)-L-lysyl-[protein] = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + (R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:16945"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:10492"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="ChEBI" id="CHEBI:83143"/>
            <dbReference type="EC" id="2.1.2.10"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GcvT family.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.10" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304565.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000507"/>
    <dbReference type="EnsemblBacteria" id="EEZ39487">
        <property type="protein sequence ID" value="EEZ39487"/>
        <property type="gene ID" value="VDA_000507"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0404">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="282830at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004047">
        <property type="term" value="F:aminomethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006546">
        <property type="term" value="P:glycine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006223">
        <property type="entry name" value="GCS_T"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028896">
        <property type="entry name" value="GCST/YgfZ/DmdA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013977">
        <property type="entry name" value="GCV_T_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006222">
        <property type="entry name" value="GCV_T_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029043">
        <property type="entry name" value="GcvT/YgfZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027266">
        <property type="entry name" value="TrmE/GcvT_dom1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43757">
        <property type="entry name" value="PTHR43757"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01571">
        <property type="entry name" value="GCV_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08669">
        <property type="entry name" value="GCV_T_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101790">
        <property type="entry name" value="SSF101790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00528">
        <property type="entry name" value="gcvT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GCV_T" evidence="7">
        <location>
            <begin position="10"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="GCV_T_C" evidence="8">
        <location>
            <begin position="298"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ39487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="372" mass="40800" checksum="7B1F243D461B1D5F" modified="2010-01-19" version="1">MTESLLMTPLNNMHKEAGAKMVPFAGYEMPVQYPLGVKKEHLHCREKAGLFDVSHMGQIRLIGEEAAKELEKLVPVDIIDLPVGKQRYALFTNEQGGIEDDLMVTNFGDCLYLVVNAACKHQDIERLKQHLAPSVTLEVLEDRALLALQGPKAAAVLAQLNPAVSDMVFMDACRLDLLGVECFVSRSGYTGEDGFEISVPNNKVEEIACHLVEFEEVEWIGLGARDSLRLECGLCLYGHDLTSSTTPVEASLLWAISPIRRLGGERAGGFPGADVILEQIKTKQIVQKRIGLIGLTKAPVREGAELLDENDQVIGTVTSGTYGPSIAQPVLMAFVDIAHTDIGMEMWALVRGKKIPVQVTKMPFVAQNYYRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4X9</accession>
    <name>D0Z4X9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000212</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39196">
        <property type="protein sequence ID" value="EEZ39196"/>
        <property type="gene ID" value="VDA_000212"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="39" mass="4470" checksum="9457A232644E3D4B" modified="2010-01-19" version="1">MDNVLQLLNTQFDIAPPKDHDEEIALIGFCRKVREPESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z517</accession>
    <name>D0Z517_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cytotoxic necrotizing factor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000250</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000250"/>
    <dbReference type="EnsemblBacteria" id="EEZ39234">
        <property type="protein sequence ID" value="EEZ39234"/>
        <property type="gene ID" value="VDA_000250"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3774">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16834">
        <property type="entry name" value="CNF1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008430">
        <property type="entry name" value="CNF_Rho-act"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037040">
        <property type="entry name" value="CNF_Rho-act_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011324">
        <property type="entry name" value="Cytotoxic_necrot_fac-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031886">
        <property type="entry name" value="DUF4765"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05785">
        <property type="entry name" value="CNF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15962">
        <property type="entry name" value="DUF4765"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64438">
        <property type="entry name" value="SSF64438"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4765" evidence="2">
        <location>
            <begin position="537"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="domain" description="CNF1" evidence="1">
        <location>
            <begin position="730"/>
            <end position="1002"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF15962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="1037" mass="116466" checksum="42ECFD62EEF6C42D" modified="2010-01-19" version="1">MNDQWQKKYLFEYNELVSKFPSPEKIISDYIKDKFNTDLHWFHWADPDNLYFVQFSQSRSNNKSYTGWDHLEKYKTNAMTLTQAAMLNMGHRFSTYDDANSVAGIYKTSNANLFDEKNEAKMLPSEYLRFIYNCDFAGLYNKALSDYWSKYYERFKLLLKNYYVSSILYLYKNNLVSKDEHDFAMAALNRENNISLFFFDIYGYYSSDIFLAENKERVMLFIPGATNPFLFSENLNSLRGRLKEIIKEQNNTSLLSTHFSLYDRQDGTSYSGVNTALNGIKENKNFDESYFFYSPKKITEKNVFEAIAILVKKRSFSDGDVLITSNSEASKEDALNILQTILSMAPIFDVIIPEVSVPASLGILATSVGLSFDQLINGDTFEERRSAIPGVVTNVLLLGLSFAIPFIISKASANKEILNEFVSNEDNILNATNTDDFLKEYSINKDDISSTSVLEINIKETEQSVNIVKLSDEDNKIIAVKGSALSGIYYEADIKTGYEIFSRRVYRTEYNNEIVWVRSGGLNGGKPFDFTTLELPIFFEDQPYSKLASSELSFINDDSPLLFPNVDSRLPASTSEMEMMHFYNDRPKFVEQDLILMRGTTEEEAWNIASTKTAGGSNEALKDISIEGHPQTDVSTTAYTTDFKSADAASRRHFLVIVKVKLKYVVGNNEVSHVNHWAIIDEAPVEVMAVVDRRFLFPEPPSQSELSILQKMLRLRFFRKNIAENASINFQKLAKGDINVLKGRGSISSTRQRAIEPYFISSNADELQGGFYTKKDRFNNLGYDTHFYNSSIGSNGAPTLNTYTGEILTDSSSLGSTYWKEHNLTNNTNIIRVSNSARGANGIKIELEQVQANKPVIITSGNLSGCTTIVARKGGWLYKVHTGTTEPVAGFTSTTGVQKAVEVFELLLKDGAGFPKVKGIMNNDFLVNYLADNFDESLITYASSDAKQGSIITVSRDNVLTFPYYTNDNLLGFGTSATILARVDNNTLVSSLSESYSLTTDGAKVSISKALSKKFNVEQLESGVSTAQPESGVSTEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5C9</accession>
    <name>D0Z5C9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative sex pilus assembly and synthesis protein TraC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000036</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000005">
        <property type="protein sequence ID" value="EEZ39051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000036"/>
    <dbReference type="EnsemblBacteria" id="EEZ39051">
        <property type="protein sequence ID" value="EEZ39051"/>
        <property type="gene ID" value="VDA_000036"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3451">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043964">
        <property type="entry name" value="P-loop_TraG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025955">
        <property type="entry name" value="TraC/Conjuga_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045978">
        <property type="entry name" value="TRAC_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19357">
        <property type="entry name" value="DUF5934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19044">
        <property type="entry name" value="P-loop_TraG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11130">
        <property type="entry name" value="TraC_F_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5934" evidence="2">
        <location>
            <begin position="311"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="domain" description="P-loop_TraG" evidence="1">
        <location>
            <begin position="452"/>
            <end position="516"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF19044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="535" mass="60190" checksum="1831307A451AD832" modified="2010-01-19" version="1">MGLLAKGKLSTLFKRAHPDAGHLHNELPYRYYNDDTELFENHQSLGFGKHLSVLGGANDELVDALNDLVMRLPEGKDWDYQFVLTGNNQVGHLIDKNCQEASVRGGIVAELAQNQAIYAHYGARHGFNTRMGSSYRFDLKNYTASFYCTSRAKEETVLDIKTSLEYGFVQAGLDHSPITPPELIDQVSQVLNFNSARNTPSKAAYNEDEHLHTQMLELDSEFLIHKGYVESRCTFDHQVEPAHTRIVNFTLRKLPPEFRLYAFSNCLASLKNAANALRCPFRISCNFRVEPTGKQRMDNEGKIRNLVKWVNSPMGRLLPTASKELAEREELQDAFLRDECKIASMIFTLTLFTDKQRMKGDVASALGVFREAGLSLIENDMVQGQALLASLPFSMLEFYDDCKMSGRARSIKTSNLVNFFPIVAEYKQLNGGVLLPTMRHQINYFHPFRMGTDNYNMAITGTSGSGKSFITQNIANAIFSEGGKEWILDKGDSYKKFTQINNGVYMTAGNIFLNPFSHILDAEQKSRGTTGGWAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5F3</accession>
    <name>D0Z5F3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_000060</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Nucleoid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the histone-like protein H-NS family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000006">
        <property type="protein sequence ID" value="EEZ39005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005307121.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000006.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39005">
        <property type="protein sequence ID" value="EEZ39005"/>
        <property type="gene ID" value="VDA_000060"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2916">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1911889at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009295">
        <property type="term" value="C:nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027444">
        <property type="entry name" value="H-NS_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037150">
        <property type="entry name" value="H-NS_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001801">
        <property type="entry name" value="Histone_HNS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027454">
        <property type="entry name" value="Histone_HNS_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00816">
        <property type="entry name" value="Histone_HNS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002096">
        <property type="entry name" value="HnS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00528">
        <property type="entry name" value="HNS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNS" evidence="9">
        <location>
            <begin position="85"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="DNA-binding region" evidence="6">
        <location>
            <begin position="109"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="83"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="23"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="92"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR002096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR002096-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ39005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="126" mass="14899" checksum="BC7CEABEBA960B79" modified="2010-01-19" version="1">MSDLMKVLLNLRSLRAISREMTLEQLQEGLDKLTQVVNERVQEEEQLRAENREKEEKLETYRQLLLADGIDPEELIQAINATPKKQTRKQRPAKYRYTEHGEEKTWTGQGRTPKFLVDKNLEDYLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5G1</accession>
    <name>D0Z5G1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CbiA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000068</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000006">
        <property type="protein sequence ID" value="EEZ39013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39013">
        <property type="protein sequence ID" value="EEZ39013"/>
        <property type="gene ID" value="VDA_000068"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1192">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1631847at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002586">
        <property type="entry name" value="CobQ/CobB/MinD/ParA_Nub-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01656">
        <property type="entry name" value="CbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="domain" description="CbiA" evidence="2">
        <location>
            <begin position="40"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="242" mass="26731" checksum="2D8A6986483ACDFD" modified="2010-01-19" version="1">MLNMKSLINESMKILINDVMFSLINAIMKTLINGGLMIVSFLSQKGGVTKSTLARAVAVAFADNDWSVHIADMDWQQQTSCKWAARRDERKIEPSISSSSHRRVDSALKIENAYNLLVIDGRPSADKDSILIAKSSELVILPTGTSLDDLEPQLHLANDLRMNGINNEKILFIVNKSPTDTEANNALDTIKSWGFKVCSHSIPFKAGYSTAQDSGLSITETRYNSLNQLTSKAIQEIVDLMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVP6</accession>
    <name>D0YVP6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">Carbonic anhydrase</fullName>
            <ecNumber evidence="3 6">4.2.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Carbonate dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_001211</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Reversible hydration of carbon dioxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>H(+) + hydrogencarbonate = CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:10748"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="EC" id="4.2.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the beta-class carbonic anhydrase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.1" evidence="3 6"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297646.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001211"/>
    <dbReference type="EnsemblBacteria" id="EEZ40189">
        <property type="protein sequence ID" value="EEZ40189"/>
        <property type="gene ID" value="VDA_001211"/>
    </dbReference>
    <dbReference type="GeneID" id="57339933"/>
    <dbReference type="eggNOG" id="COG0288">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1841447at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004089">
        <property type="term" value="F:carbonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015976">
        <property type="term" value="P:carbon utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001765">
        <property type="entry name" value="Carbonic_anhydrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015892">
        <property type="entry name" value="Carbonic_anhydrase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036874">
        <property type="entry name" value="Carbonic_anhydrase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11002">
        <property type="entry name" value="PTHR11002"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00484">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00947">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53056">
        <property type="entry name" value="SSF53056"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00704">
        <property type="entry name" value="PROK_CO2_ANHYDRASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00705">
        <property type="entry name" value="PROK_CO2_ANHYDRASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="223" mass="24921" checksum="5BC7C41E68C13274" modified="2010-01-19" version="1">MADIKQLFANNLAWSENIKEETPEFFSHLAEAQHPQYLWIGCSDSRVPAERLTGLDSGELFVHRNVANQVIHTDLNCLSVVQYAVDVLKVRHIIICGHYGCGGVTAAIENPQLGLINNWLLHIRDLYLKHRSDLGALDREDWDNKLCEINVASQVYNLGNSTIMQQAWERGQQVKIHGWIYGIGDGVLRDLGVTATSRESLEVSYQAAMSAILPAVEALEKSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVR2</accession>
    <name>D0YVR2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATP binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002003</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299149.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002003"/>
    <dbReference type="EnsemblBacteria" id="EEZ40971">
        <property type="protein sequence ID" value="EEZ40971"/>
        <property type="gene ID" value="VDA_002003"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3950">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="318943at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041685">
        <property type="entry name" value="AAA_15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13175">
        <property type="entry name" value="AAA_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13304">
        <property type="entry name" value="AAA_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_15" evidence="1">
        <location>
            <begin position="1"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="ATPase_AAA_core" evidence="2">
        <location>
            <begin position="296"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="443" mass="50065" checksum="7D0EFC159AA8E0D4" modified="2010-01-19" version="1">MKISKINVKNFKKIRNLDLDIPADNRVICFVGENGANKSSLLSALYANLRQTSGVTSPSDGQDRYVDNLNHVSTSVSADERFSLLSLSLSENDAVIKSDRAIVPSLEDLSEENKQLLRTTFNIFYSEDIKFLLGQSNFRNLDSYNPDLVRQNVVLFRPFNRTETPTWERESLSENQDVVATGHNIIGKRKFPMRVASGIEKTNSYFLDVVLDHLIDSSNNSDTTYSLFNNFREILSTIEPAANGTFVVQEFPNKCISFPNVPELASLSAGQSDWFVTAINILIQMKELARNIAPELIRNVGGIVFIDEMDMNYHPSFQERVLPWFLDFFPNIQFIITTHSPYLIRSLGENSLVVKLPSGEVLDDDFSYYDINEVALKVFGQDQGFSPIVKDKLVELKRALNESNNVVARAIYDQLITKSESLDRELNKIVMTVADEEFIGGLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVT6</accession>
    <name>D0YVT6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA-uridine aminocarboxypropyltransferase</fullName>
            <ecNumber evidence="1">2.5.1.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_002017</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.5.1.25" evidence="1"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299187.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002017"/>
    <dbReference type="EnsemblBacteria" id="EEZ40985">
        <property type="protein sequence ID" value="EEZ40985"/>
        <property type="gene ID" value="VDA_002017"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3148">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1600710at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016432">
        <property type="term" value="F:tRNA-uridine aminocarboxypropyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005636">
        <property type="entry name" value="DTW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039262">
        <property type="entry name" value="DTWD2/YfiP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21392">
        <property type="entry name" value="PTHR21392"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03942">
        <property type="entry name" value="DTW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01144">
        <property type="entry name" value="DTW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="DTW" evidence="5">
        <location>
            <begin position="27"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="240" mass="27835" checksum="93356DDA85877D9D" modified="2010-01-19" version="1">MRIHAVHTLYEERLARSTRPFRARGCKVERCRQCMLRPHLCICEHRPTVNSNAAFLLVMYDTEVLKPSNTGRLIADLFEDTFAYIWSRTEENTEMMALLNDPQWQPYVVFPAEYAEPERVAEKVELAQGKRPLFIMLDGSWAEAKKMFRKSPYLAQFPVLSIDPEQPSRYKVREASKENQLGTAEVAAKIIEQFGETRNAEVLDLWFDVFRDHYIAGKMNRELADDTAMTALKSRLAHCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVX7</accession>
    <name>D0YVX7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Anti-sigma-E factor RseA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Regulator of SigE</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Sigma-E anti-sigma factor RseA</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Sigma-E factor negative regulatory protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_001258</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Interacts 1:1 with ECF RNA polymerase sigma-E (RpoE); this inhibits the interaction of sigma-E with the RNA polymerase catalytic core and leads to a decreased expression of sigma-E-regulated genes. Interacts with RseB.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the RseA family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297743.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001258"/>
    <dbReference type="EnsemblBacteria" id="EEZ40236">
        <property type="protein sequence ID" value="EEZ40236"/>
        <property type="gene ID" value="VDA_001258"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3073">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1628369at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016989">
        <property type="term" value="F:sigma factor antagonist activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16328">
        <property type="entry name" value="RseA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005573">
        <property type="entry name" value="Anti-sigma_E_RseA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005572">
        <property type="entry name" value="Anti-sigma_E_RseA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036147">
        <property type="entry name" value="Anti-sigma_E_RseA_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026279">
        <property type="entry name" value="RseA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03873">
        <property type="entry name" value="RseA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03872">
        <property type="entry name" value="RseA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016938">
        <property type="entry name" value="RseA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89069">
        <property type="entry name" value="SSF89069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="2 6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="RseA_N" evidence="7">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="RseA_C" evidence="8">
        <location>
            <begin position="141"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR016938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ40236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="216" mass="23593" checksum="E12840C84C2D82B9" modified="2010-01-19" version="1">MADKEKISALLDGEDLDQSIINALTVDKESELSWHDYNLIGDVMRGDAPQCKEWDIAANVALALDAEPAHSVSTAEVVDIQVAKDIVESQPTPQQAKRFLPAWLTQFGQVAVAACVSLAVIVGVQQYNGSDSNATNAPETMPVLQTIPFAGKAEPVSFTRDSLRNSHSSAPSEAQLMEQRRRINAMLQDYELQLRFNAEDGSIDKTKLETDNTVAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW36</accession>
    <name>D0YW36_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Alanine--tRNA ligase</fullName>
            <ecNumber evidence="11">6.1.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Alanyl-tRNA synthetase</fullName>
            <shortName evidence="11">AlaRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">alaS</name>
        <name evidence="14" type="ORF">VDA_001299</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala)</text>
            <dbReference type="Rhea" id="RHEA:12540"/>
            <dbReference type="Rhea" id="RHEA-COMP:9657"/>
            <dbReference type="Rhea" id="RHEA-COMP:9923"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78497"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="11">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="11">Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.7" evidence="11"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297824.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001299"/>
    <dbReference type="EnsemblBacteria" id="EEZ40274">
        <property type="protein sequence ID" value="EEZ40274"/>
        <property type="gene ID" value="VDA_001299"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0013">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="91428at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004813">
        <property type="term" value="F:alanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006419">
        <property type="term" value="P:alanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00036_B">
        <property type="entry name" value="Ala_tRNA_synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002318">
        <property type="entry name" value="Ala-tRNA-lgiase_IIc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018162">
        <property type="entry name" value="Ala-tRNA-ligase_IIc_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018165">
        <property type="entry name" value="Ala-tRNA-synth_IIc_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018164">
        <property type="entry name" value="Ala-tRNA-synth_IIc_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023033">
        <property type="entry name" value="Ala_tRNA_ligase_euk/bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003156">
        <property type="entry name" value="DHHA1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012947">
        <property type="entry name" value="tRNA_SAD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02272">
        <property type="entry name" value="DHHA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01411">
        <property type="entry name" value="tRNA-synt_2c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07973">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00980">
        <property type="entry name" value="TRNASYNTHALA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00863">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101353">
        <property type="entry name" value="SSF101353"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="SSF55186"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00344">
        <property type="entry name" value="alaS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50860">
        <property type="entry name" value="AA_TRNA_LIGASE_II_ALA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11 14" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 11 14" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 11" id="KW-0820">tRNA-binding</keyword>
    <keyword evidence="6 11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II_ALA" evidence="13">
        <location>
            <begin position="3"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="730"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="562"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="566"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="664"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="668"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEZ40274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="873" mass="95150" checksum="98FFEB60E20255B3" modified="2010-01-19" version="1">MYMSTDEIRRAYLAFFESKGHQIVESSSLVPANDPTLLFTNAGMNQFKDVFLGLEKRSYTRATTAQRCVRAGGKHNDLENVGFTARHHTFFEMLGNFSFGDYFKHDAIKYAWEFLTTVLELPEDRLLVTIYESDDEAFEIWNKEVGIPADRIVRIGDNKGAPFASDNFWQMGDTGPCGPCTEIFFDHGDHIWGGRPGTPEEDGDRFIEIWNNVFMQYNRQADGTMEPLPKPSVDTGMGIERIAAIMQGVHSNYEIDIFKTLIKDAADIIGYDDLSNQSLRVVADHIRSCAYLIADGVMPSNEGRGYVLRRIIRRAVRHGNKLGAKGAFFYKLVGPLADVMGTAGSELKKQQEMVEKVLKIEEENFGRTLDRGLTILNEALDNLDGSILDGETVFKLYDTYGFPADLTNDVARERGFTIDEEGFEAAMEEQRQRARDAGQFGVDYNNVIKVDADTEFKGYEATDGEGVIVAIYRDGEEVDALAAGEEAIIVLDQTPFYAESGGQCGDTGALAAAGVAFTVADTQKFGHAIGHKGTLTEGALKVGDKLAATVDHVRRGAISLNHSATHLMHAALRKLLGEHVAQKGSLVKPDSLRFDFSHLEAVKPEQLREVERMVNDQIRLNHAIDTEIMDIEAAKEKGAMALFGEKYDDQVRVLSMGDFSTELCGGIHAKRTGDIGLFKIVSEGGIAAGIRRIEAVTGAAAIEALHAQDEQLAKAARLVKSDTASVVNKVEALVSHSKQLEKEIQQLKDKLAAQEGAGLINQAQEINGVKVLIAKLDGADNKALRGMVDELKNQLSSGIVVLGNVSDDKVGLIAGVTKDLIGKVKAGELVNMVAQQVGGKGGGRPDMAQAGGTDASALPAALESAKAWIEERL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW65</accession>
    <name>D0YW65_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NADPH-dependent 7-cyano-7-deazaguanine reductase</fullName>
            <ecNumber evidence="2">1.7.1.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">7-cyano-7-carbaguanine reductase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">NADPH-dependent nitrile oxidoreductase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">PreQ(0) reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">queF</name>
        <name evidence="5" type="ORF">VDA_001350</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>7-aminomethyl-7-carbaguanine + 2 NADP(+) = 7-cyano-7-deazaguanine + 3 H(+) + 2 NADPH</text>
            <dbReference type="Rhea" id="RHEA:13409"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:45075"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58703"/>
            <dbReference type="EC" id="1.7.1.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">tRNA modification; tRNA-queuosine biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.7.1.13" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297900.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001350"/>
    <dbReference type="EnsemblBacteria" id="EEZ40325">
        <property type="protein sequence ID" value="EEZ40325"/>
        <property type="gene ID" value="VDA_001350"/>
    </dbReference>
    <dbReference type="GeneID" id="57339747"/>
    <dbReference type="eggNOG" id="COG0780">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2904">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1525536at2"/>
    <dbReference type="UniPathway" id="UPA00392"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046857">
        <property type="term" value="F:oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033739">
        <property type="term" value="F:preQ1 synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:queuosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1130.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00817">
        <property type="entry name" value="QueF_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043133">
        <property type="entry name" value="GTP-CH-I_C/QueF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029500">
        <property type="entry name" value="QueF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029139">
        <property type="entry name" value="QueF_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016428">
        <property type="entry name" value="QueF_type2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14489">
        <property type="entry name" value="QueF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14819">
        <property type="entry name" value="QueF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004750">
        <property type="entry name" value="Nitrile_oxidored_YqcD_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03138">
        <property type="entry name" value="QueF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="QueF_N" evidence="4">
        <location>
            <begin position="21"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="88"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="228"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="263"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="265"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="active site" description="Thioimide intermediate" evidence="2">
        <location>
            <position position="189"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="196"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="90"/>
            <end position="91"/>
        </location>
        <ligand>
            <name>NADPH</name>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="257"/>
            <end position="258"/>
        </location>
        <ligand>
            <name>NADPH</name>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF14819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="282" mass="32504" checksum="8D71570C7FAE6E97" modified="2010-01-19" version="1">MSKYQGAKELAGLTLGQKTEYKDQYDPSLLQPVPRSLNRNDLHITDDNLPFTGYDIWTLYELSWLNSKGLPQVAIGEVRLPASSPNLIESKSFKLYLNSLNQTRFASWQEVADVLQIDLSACAGQDVDVTIQPLSDFTEEQIVAFTGHNIDDQDIEIDDYQFNPAYLEDAIDDEIVTEELNSNLLKSNCLITSQPDWGSVRISYKGKRINREKLLRYIISFRNHNEFHEQCVERIFTDIMKYCQPELLTVYARYTRRGGLDINPYRTNQGKTPSNNFRMARQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW87</accession>
    <name>D0YW87_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ</fullName>
            <ecNumber evidence="3">4.2.1.59</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Beta-hydroxyacyl-ACP dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">VDA_001369</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the thioester dehydratase family. FabZ subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.59" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001369"/>
    <dbReference type="EnsemblBacteria" id="EEZ40344">
        <property type="protein sequence ID" value="EEZ40344"/>
        <property type="gene ID" value="VDA_001369"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0764">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008659">
        <property type="term" value="F:(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008693">
        <property type="term" value="F:3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047451">
        <property type="term" value="F:3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004317">
        <property type="term" value="F:3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013114">
        <property type="entry name" value="FabA_FabZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010084">
        <property type="entry name" value="FabZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30272">
        <property type="entry name" value="PTHR30272"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07977">
        <property type="entry name" value="FabA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01750">
        <property type="entry name" value="fabZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword evidence="6" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9" id="KW-0456">Lyase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ40344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="127" mass="14148" checksum="AE7198482E447A37" modified="2010-01-19" version="1">MIDRVVNYEEGKTLTAIKNVSINEPQFTGHFPNMPVFPGVLILEAMAQATGLLAFKTFGAPKENELYYFASIDNAKFRKPVMPGDQLVLEVEFLKERRGIAMFNGVAKVDGDVVCSAELKCARREFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWA4</accession>
    <name>D0YWA4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001182</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40160">
        <property type="protein sequence ID" value="EEZ40160"/>
        <property type="gene ID" value="VDA_001182"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4701">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="69" mass="7491" checksum="2CE3D9F5FA16CC77" modified="2010-01-19" version="1">MVDIQVKVNPNLAAVQVAKHNKTPDIVQKPISDVAASHLLQAAEHASEKVKARLERLAQLAKKNKEGSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWA5</accession>
    <name>D0YWA5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="13 14">Protein translocase subunit SecA</fullName>
            <ecNumber evidence="13">7.4.2.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">secA</name>
        <name evidence="18" type="ORF">VDA_001183</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="13">Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cell membrane</location>
            <topology evidence="13">Peripheral membrane protein</topology>
            <orientation evidence="13">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="13">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="13">Distribution is 50-50.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 13 14">Belongs to the SecA family.</text>
    </comment>
    <dbReference type="EC" id="7.4.2.8" evidence="13"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297588.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001183"/>
    <dbReference type="EnsemblBacteria" id="EEZ40161">
        <property type="protein sequence ID" value="EEZ40161"/>
        <property type="gene ID" value="VDA_001183"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0653">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="212453at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017038">
        <property type="term" value="P:protein import"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd18803">
        <property type="entry name" value="SF2_C_secA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01382">
        <property type="entry name" value="SecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004027">
        <property type="entry name" value="SEC_C_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000185">
        <property type="entry name" value="SecA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020937">
        <property type="entry name" value="SecA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011115">
        <property type="entry name" value="SecA_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014018">
        <property type="entry name" value="SecA_motor_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011130">
        <property type="entry name" value="SecA_preprotein_X-link_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044722">
        <property type="entry name" value="SecA_SF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011116">
        <property type="entry name" value="SecA_Wing/Scaffold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036266">
        <property type="entry name" value="SecA_Wing/Scaffold_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036670">
        <property type="entry name" value="SecA_X-link_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30612">
        <property type="entry name" value="PTHR30612"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02810">
        <property type="entry name" value="SEC-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07517">
        <property type="entry name" value="SecA_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01043">
        <property type="entry name" value="SecA_PP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07516">
        <property type="entry name" value="SecA_SW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00906">
        <property type="entry name" value="SECA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00957">
        <property type="entry name" value="SecA_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00958">
        <property type="entry name" value="SecA_PP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81767">
        <property type="entry name" value="SSF81767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81886">
        <property type="entry name" value="SSF81886"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00963">
        <property type="entry name" value="secA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01312">
        <property type="entry name" value="SECA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51196">
        <property type="entry name" value="SECA_MOTOR_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 13" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="18" id="KW-0347">Helicase</keyword>
    <keyword evidence="18" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 13 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 13 14" id="KW-0653">Protein transport</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 13" id="KW-1278">Translocase</keyword>
    <keyword evidence="11 13 14" id="KW-0811">Translocation</keyword>
    <keyword evidence="3 13 14" id="KW-0813">Transport</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="SECA_MOTOR_DEAD" evidence="17">
        <location>
            <begin position="3"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="16">
        <location>
            <begin position="89"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="849"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="861"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="105"/>
            <end position="109"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="512"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EEZ40161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="906" mass="103549" checksum="B45A041585B75DAB" modified="2010-01-19" version="1">MLSKLLTKIIGSRNDRTLRRMRKIVDQINKLEPQFESLQDEELKAKTAEFRSRLEQGETLDQLLPEAFATVRESSKRLYGMRHFDVQLIGGMVLNDCKIAEMRTGEGKTLTATLPAYLNALTGKGVHIVTVNDYLASRDAETNRPLFEFLGMTVGVNVPNMPPHAKKEAYEADVLYGTNNEFGFDYLRDNMAFRPEDRVQRERFFAVVDEVDSILIDEARTPLIISGPAEDSSELYIRMNTLIPNLEKQDKEDSEEYRGEGHYTVDEKSKQAHLTENGQEYVEELLIKNGLMAENDTLYSPANISLLHHVNAALRAHVLFERDVDYIVQDGEVVIVDEHTGRTMPGRRWSEGLHQAVEAKEGVKIQNENQTLASITFQNYFRLYEKLSGMTGTADTEAFEFQSIYGLDTVVIPTNRPMARLDHGDLVYMTEAEKFAAIAEDIKERVANGQPCLVGTVSIEKSELLSNALKKAGIKHNVLNAKFHEKEAEIVAQAGYPGAVTIATNMAGRGTDIMLGGSWKAEAEKLENPTDEQIAKLKADWQVRHDAVLASGGLHIIGTERHESRRIDNQLRGRSGRQGDAGSSRFYLSMEDALMRIFASDRVSNMMKKLGMEEGEAIEHPWVTKAIENAQRKVEGRNFDIRKQLLEFDDVANDQRKVVYELRDELMFADDISDMIEHNREDVLNAIIDAYIPPQSLEEMWDIDGLEDRLRTDYDLDLPIKHWLETEDKLYEEALRERIVEKAVELYREKESVVGPEVLRNFEKTVMLQNLDTLWKEHLAAMDHLRQGIHLRGYAQKNPKQEYKRESFELFEEMLDNLKSDVISILSKVRVQQQEEVERMEEERRQMAEALAQKQQFHHQTSDEALADEEDGTQGTYEREERKVGRNEPCPCGSGKKYKQCHGKIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWC6</accession>
    <name>D0YWC6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC-type oligopeptide transport system ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001389</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297980.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001389"/>
    <dbReference type="EnsemblBacteria" id="EEZ40364">
        <property type="protein sequence ID" value="EEZ40364"/>
        <property type="gene ID" value="VDA_001389"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4608">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1303270at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="5"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="47"/>
            <end position="54"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="276" mass="31051" checksum="FC15ED3B7473229F" modified="2010-01-19" version="1">MSEVLRATDLCQYFYNGGGFFRKGEEIKAVDGVSLIVNAGETLGLVGESGCGKSTLGRALLKLYQPSRGEIFFQGQNITQFSVKKMRPLRKEMQIVFQDPMESLNPRHTVGMILEEPFIIHKLGTKAERQIWVDELLVKVGLPISAKDRYPHEFSGGQRQRIGIARAIALKPKLLICDESVSALDVSVQAQILNLLLQLQQEMNLAMIFISHDLSVVKHISDRVAVMYFGKIVETGPTEQVFLHPKASYTKQLLAAIPVTHPRDRRKRRLQRDQVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWD5</accession>
    <name>D0YWD5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">Uracil phosphoribosyltransferase</fullName>
            <ecNumber evidence="3 11">2.4.2.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 11">UMP pyrophosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">UPRTase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">upp</name>
        <name evidence="12" type="ORF">VDA_001405</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>diphosphate + UMP = 5-phospho-alpha-D-ribose 1-diphosphate + uracil</text>
            <dbReference type="Rhea" id="RHEA:13017"/>
            <dbReference type="ChEBI" id="CHEBI:17568"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="EC" id="2.4.2.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="11">Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.</text>
    </comment>
    <comment type="activity regulation">
        <text evidence="11">Allosterically activated by GTP.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 11">Pyrimidine metabolism; UMP biosynthesis via salvage pathway; UMP from uracil: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the UPRTase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.9" evidence="3 11"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298011.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001405"/>
    <dbReference type="EnsemblBacteria" id="EEZ40380">
        <property type="protein sequence ID" value="EEZ40380"/>
        <property type="gene ID" value="VDA_001405"/>
    </dbReference>
    <dbReference type="GeneID" id="57339674"/>
    <dbReference type="eggNOG" id="COG0035">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1581906at2"/>
    <dbReference type="UniPathway" id="UPA00574">
        <property type="reaction ID" value="UER00636"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004845">
        <property type="term" value="F:uracil phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044206">
        <property type="term" value="P:UMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006223">
        <property type="term" value="P:uracil salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01218_B">
        <property type="entry name" value="Upp_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034332">
        <property type="entry name" value="Upp_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005765">
        <property type="entry name" value="Ura_phspho_trans"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01091">
        <property type="entry name" value="upp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="5 11 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 11" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11 12" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="5-phospho-alpha-D-ribose 1-diphosphate binding" evidence="11">
        <location>
            <begin position="130"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Uracil binding" evidence="11">
        <location>
            <begin position="198"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>uracil</name>
            <dbReference type="ChEBI" id="CHEBI:17568"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ40380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="208" mass="22741" checksum="4AB0313E06880078" modified="2010-01-19" version="1">MKVVEVKHPLVKHKIGLMREGDISTKRFRELATEVGSLLTYEATSDFETEKVTIEGWNGQVEIDQIKGKKVTVVPILRAGLGMMDGVLEHMPSARISVVGIYRDEETLEPVPYFNKLASNIDERIALVVDPMLATGGSMIATLDLLKEHGCKQFKVLVLVAAPEGIAALEKAHPDIELYTAAIDEKLNDKGYIVPGLGDAGDKIFGTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWD9</accession>
    <name>D0YWD9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Trp repressor-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001410</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298017.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001410"/>
    <dbReference type="EnsemblBacteria" id="EEZ40384">
        <property type="protein sequence ID" value="EEZ40384"/>
        <property type="gene ID" value="VDA_001410"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0655">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="796211at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001226">
        <property type="entry name" value="Flavodoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005025">
        <property type="entry name" value="FMN_Rdtase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03358">
        <property type="entry name" value="FMN_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00201">
        <property type="entry name" value="FLAVODOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0288">FMN</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="4">
        <location>
            <begin position="4"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="191" mass="20778" checksum="BAECDC11547E14C2" modified="2010-01-19" version="1">MLKILILYYSQHGNTRQLARHIARGVEQIAECEAVLRTVPTLENGQLQQQSTTDPFVCKQDLEQCAGLALGSPVHFGNMAAPLKWFIDSTSSQWLAGTLIDKPACVFTSSSSLHGGQETTLQSMMLPLFHHGMMVLGLPYSEPALHHTQAGGTPYGCSHVNHGIRQLDSSEITLAQAMGKRLAQTAKKLAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWF8</accession>
    <name>D0YWF8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Outer membrane protein assembly factor BamC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">bamC</name>
        <name evidence="5" type="ORF">VDA_001417</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the Bam complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the BamC family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298028.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="SMR" id="D0YWF8"/>
    <dbReference type="STRING" id="675817.VDA_001417"/>
    <dbReference type="EnsemblBacteria" id="EEZ40391">
        <property type="protein sequence ID" value="EEZ40391"/>
        <property type="gene ID" value="VDA_001417"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3317">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1197067at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043165">
        <property type="term" value="P:Gram-negative-bacterium-type cell outer membrane assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051205">
        <property type="term" value="P:protein insertion into membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00924">
        <property type="entry name" value="OM_assembly_BamC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014524">
        <property type="entry name" value="BamC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042268">
        <property type="entry name" value="BamC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010653">
        <property type="entry name" value="NlpB/DapX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06804">
        <property type="entry name" value="Lipoprotein_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="337" mass="37299" checksum="AF0266EF322663A9" modified="2010-01-19" version="1">MNHNYKLAIAAVIVTTLTACSSADRRRQANNDFNYLDTQPLESWTQPEGARAFDTNVYAIPTQSFSGEIGSQVDIRPPAEILNLIPGARSFHDQEGVTMLLPSSAEMNRLWNVTKQMITKRDVKLLSDTTNEIKTDWVSWTDEEKDAKISSRFDIVRSPAENSFRVKLAAMQQDGKDVAITPAIQARSSITVANIVSVAYDQQLRDEAAARAQEMLKHVPITMSTDNAGLPVIIARAPYNLFWDRLPTVLEQLGFSVEDKNESQGTMTVKYSAPDDDYWEKLGVQPINLDNDTYKIQVGDLGNRTSISVNDDDGKPVTAQALQSLAPVLAAQLAHSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWJ3</accession>
    <name>D0YWJ3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Glutathione synthetase</fullName>
            <ecNumber evidence="10">6.3.2.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">GSH synthetase</fullName>
            <shortName evidence="10">GSH-S</shortName>
            <shortName evidence="10">GSHase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Glutathione synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">gshB</name>
        <name evidence="13" type="ORF">VDA_001235</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + glutathione + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13557"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:58173"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="10">Sulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the prokaryotic GSH synthase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.3" evidence="10"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297697.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001235"/>
    <dbReference type="EnsemblBacteria" id="EEZ40213">
        <property type="protein sequence ID" value="EEZ40213"/>
        <property type="gene ID" value="VDA_001235"/>
    </dbReference>
    <dbReference type="GeneID" id="57339887"/>
    <dbReference type="eggNOG" id="COG0189">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="878336at2"/>
    <dbReference type="UniPathway" id="UPA00142">
        <property type="reaction ID" value="UER00210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004363">
        <property type="term" value="F:glutathione synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00162">
        <property type="entry name" value="GSH_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006284">
        <property type="entry name" value="Glut_synth_pro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004218">
        <property type="entry name" value="GSHS_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004215">
        <property type="entry name" value="GSHS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21621:SF4">
        <property type="entry name" value="PTHR21621:SF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02955">
        <property type="entry name" value="GSH-S_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02951">
        <property type="entry name" value="GSH-S_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01380">
        <property type="entry name" value="glut_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 10" id="KW-0317">Glutathione biosynthesis</keyword>
    <keyword evidence="3 10 13" id="KW-0436">Ligase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0464">Manganese</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="12">
        <location>
            <begin position="124"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ40213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="315" mass="35232" checksum="E4EB2812EC5FED4C" modified="2010-01-19" version="1">MIKLGIVMDPIESINIKKDSSFAMMMEAQRRGWEIHYMEMNDLSLEQGKAVARTRVVSLKEDPNGWFEFQSEQEIALSELDAVLMRKDPPFDTEYIYATYILERAEVEGTLIVNKPQSLRDCNEKLFTAWFPELTPTTMVTRRADKIKAFHQQHGDVILKPLDGMGGSSIFRVMNGDPNVSVIIETLTNMGQNYCMAQTFVPDISNGDKRILVVDGEPMPYCLARIPAKGETRGNLAAGGRGEARPLSETDRRIAEAVAPTLKEKGLIFVGLDVIGDKLTEINVTSPTCIREIEAAFDISITGKLMDAIERRLGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWN8</accession>
    <name>D0YWN8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">UTP--glucose-1-phosphate uridylyltransferase</fullName>
            <ecNumber evidence="3 5">2.7.7.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">UDP-glucose pyrophosphorylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_001524</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>alpha-D-glucose 1-phosphate + H(+) + UTP = diphosphate + UDP-alpha-D-glucose</text>
            <dbReference type="Rhea" id="RHEA:19889"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="2.7.7.9"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the UDPGP type 2 family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.9" evidence="3 5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001524"/>
    <dbReference type="EnsemblBacteria" id="EEZ40498">
        <property type="protein sequence ID" value="EEZ40498"/>
        <property type="gene ID" value="VDA_001524"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1210">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1402673at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003983">
        <property type="term" value="F:UTP:glucose-1-phosphate uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006011">
        <property type="term" value="P:UDP-glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02541">
        <property type="entry name" value="UGPase_prokaryotic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005771">
        <property type="entry name" value="GalU_uridylyltTrfase_bac/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43197">
        <property type="entry name" value="PTHR43197"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01099">
        <property type="entry name" value="galU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transferase" evidence="6">
        <location>
            <begin position="6"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="296" mass="32407" checksum="D1BB6066CBE410A4" modified="2010-01-19" version="1">MMYITKAVIPVAGLGTRMLPATKAIPKEMLPLVDKPLIQFIVNECVNAGIKEIVLVTHSSKNAIENHFDTSFELEATLEARVKRQLLDEVQNICPRDVTVMHVRQGHAKGLGHAVLCAKPLVGDAPFAVVLPDVILDEYTADQSKENLAAMLQRYEETGASQIMVEPVPMSDVSKYGVVDCNGTELVAGESCPMTRMVEKPAVEDAPSNLAVVGRYVLSHKIWDKLAITPPGAGDEIQLTDAIDMLMAEETVEAFHMSGKSHDCGDKLGYLKAFVEYGMRHKDLGEDFKAYLKANN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWR9</accession>
    <name>D0YWR9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphoesterase</fullName>
            <ecNumber evidence="3">3.1.4.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001464</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the metallophosphoesterase superfamily. YfcE family.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.-" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298108.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001464"/>
    <dbReference type="EnsemblBacteria" id="EEZ40438">
        <property type="protein sequence ID" value="EEZ40438"/>
        <property type="gene ID" value="VDA_001464"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0622">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1355703at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110165">
        <property type="term" value="C:cellular anatomical entity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00841">
        <property type="entry name" value="MPP_YfcE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024654">
        <property type="entry name" value="Calcineurin-like_PHP_lpxH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041802">
        <property type="entry name" value="MPP_YfcE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020935">
        <property type="entry name" value="PdiEstase_YfcE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000979">
        <property type="entry name" value="Phosphodiesterase_MJ0936/Vps29"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11124">
        <property type="entry name" value="PTHR11124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12850">
        <property type="entry name" value="Metallophos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00040">
        <property type="entry name" value="yfcE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01269">
        <property type="entry name" value="UPF0025"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos_2" evidence="4">
        <location>
            <begin position="1"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="182" mass="20327" checksum="65EB84809F90CA89" modified="2010-01-19" version="1">MKLFIASDIHGCAVSTHNMLQRFEQSGAEYLILLGDILNHGPRNALPSGYDPIKVSELLNPYADRIMAVRGNCDSEVDQMLLQFPLMSDFNWVLLPTGQRLFLTHGHLYNKEKHPKLRAGDVIVSGHTHIPVAEMMDELYLFNPGSITIPRNGLPASYGLLEGNQLIVKTFDDEVLQQVCIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWS3</accession>
    <name>D0YWS3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative SAM-dependent methyltransferase</fullName>
            <ecNumber evidence="4">2.1.1.51</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001468</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.1.1.51" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298115.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001468"/>
    <dbReference type="EnsemblBacteria" id="EEZ40442">
        <property type="protein sequence ID" value="EEZ40442"/>
        <property type="gene ID" value="VDA_001468"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1865374at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016718">
        <property type="entry name" value="rRNA_m1G-MeTrfase_A_prd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13847">
        <property type="entry name" value="Methyltransf_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018249">
        <property type="entry name" value="MyrA_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Methyltranfer_dom" evidence="3">
        <location>
            <begin position="86"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="2">
        <location>
            <begin position="96"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="5"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="21"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="25"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR018249-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR018249-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="275" mass="31690" checksum="14DA3FC5CCE9DA9F" modified="2010-01-19" version="1">MSYQCPLCHHSLSLTDHHWRCQNNHQFDVAKEGYVNLMPAHHKSSKNPGDNKEMMQARRLFLNTDHYQPLRDAVIAQLQQHLPEQAQQLLDIGCGEGYYTSEFEQLHSQYPELQIHGLDISKVAVKYAAKRYHNCHFCVASSHRLPFADDFLDGVVRIYAPCKGEELYRTIKAEGILVAVTPAPRHLYQLKELIYSDVHLHDVPPEDIDGFELIVDDNLHYDMTLNGEEASALMQMTPFAWKTSEAVWQQLKAAQNFRCEADFAIRVYKKHSNKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-06-02" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWU2</accession>
    <name>D0YWU2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001534</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298229.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001534"/>
    <dbReference type="EnsemblBacteria" id="EEZ40508">
        <property type="protein sequence ID" value="EEZ40508"/>
        <property type="gene ID" value="VDA_001534"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3170">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1182445at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.2200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038440">
        <property type="entry name" value="FimV_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020011">
        <property type="entry name" value="Motility_prot_FimV_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020012">
        <property type="entry name" value="Motility_prot_FimV_N"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03505">
        <property type="entry name" value="FimV_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03504">
        <property type="entry name" value="FimV_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018693" evidence="3">
        <location>
            <begin position="30"/>
            <end position="1330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="152"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="257"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="444"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="496"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="648"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="700"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="836"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="974"/>
            <end position="1041"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1073"/>
            <end position="1094"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1139"/>
            <end position="1183"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="345"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="183"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="259"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="496"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="651"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="701"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="861"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="927"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="998"/>
            <end position="1030"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1156"/>
            <end position="1180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="1330" mass="146754" checksum="204B6313C4338019" modified="2010-01-19" version="1">MSELSQALKRILLPVALATAFGGIAPAYANTVRIVGPENEDPNAWVQHSEQMRSSSFDYVKTPNKPYTNMRRYGPTSAKETLWSIASRHRPNNSVSVYQVIGAIKHINPQAFENNNIHGLIPGSYLVMPTLAQVKREDTQLVRRVLEQDKLREPYASKNRKTTSKPSAKKTVVKKAPVKHAVPASQTRSQTKAQPKPQIKPAVNPAKSTSTTVESADHFTIPAKPTVPANKVSPSATKAALATVATATVLGPMAVDTGEPITEQSSATKVNTEQSKAITSAPAQVTSSATEGDNTGANTVSSQSNTASVQRDGAIPPKPQDVSANAAASLPQDVSNPLNASDEQLTQLIESNHMLKVRLAEMQQEMASLREQVGDDDEFRNEVINFIRQQRQQEQAVPEEDKTSWLNQLADNPTALIAAGLIPGGLLAGLLAFFLYRRGKKEEQEEQAEKNSQLPLIDDASSSEPNLDSEDKLDELDDLLFDDDLFADSNDKLEQSLDRDLKQSEKTGLSESELSEAKLSESKPSESETSQSDPAPGPNFFLDDFDINDDFDVDMSSKSVSVNGEEAALGLEEMERAIDQMDTSHSDEDLAAQWERSLQQEKVDVDSDDFDLAEGLDESFEPLEPKSEQELLDQSMLDDLLVDIDSQLEEPVTSEAASDVISNEKASLEPQLEQEPFTSPTVEDSVQKTIDELDISSKELVEESANPTSNISAESQTIPEVETEISESSTQLLDELVTDEDDLLGADLDIDLDENSVQLLDELIPDEDDEIVLEQPLDLEENSTALLDELVDDWGEKPTKAIDATVEQSQEIEPLQTQVAEEDIDDILDQFLDQELEQHTLADEAQESSPHDYLAPEAKPLTVEELERELDRQEAEEKQSLAQAIDEFPIFDEQAALDEFDEREPNSHAMPETKAQSESHIEAFELDDLPEFDEQSALNDPEAESLLDEELALSDEDQQRALDNVVRQLQEAVEASERYQQAPELLDTIDTKLSESKETPPQELTSSEEITKESISEPSMTDVSSEPSSEPSAFDEHKKKDYDFAHYDPASLPEFNEDEALQASFEEQYELEQYEREKGFSTQRPPHPIQDDYVANSAQPLPSEFDHELVESAGLDMAALLTDPDLGLADAERDGLLAHVHNDTQDDDDLDSDEQALWHQVSQDPSLENEDWSQQPSLAKDDIDSVIESIEHELEPAQEKGAYKAFQQAEELTLPEAGSELISVAQDSKPHSFISIDELMKETQGDGSALAQELDAQPLKLDVGLDEFPDVLTNIAHTDVDDHSELASKLDLAKAYLEMNDKEGAIELLEEVTAKADGAVKAEAEKLLNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWU4</accession>
    <name>D0YWU4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA pseudouridine synthase A</fullName>
            <ecNumber evidence="4">5.4.99.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">tRNA pseudouridine(38-40) synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA pseudouridylate synthase I</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA-uridine isomerase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">truA</name>
        <name evidence="9" type="ORF">VDA_001536</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 7">
            <text>uridine(38/39/40) in tRNA = pseudouridine(38/39/40) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:22376"/>
            <dbReference type="Rhea" id="RHEA-COMP:10085"/>
            <dbReference type="Rhea" id="RHEA-COMP:10087"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="EC" id="5.4.99.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 7">Belongs to the tRNA pseudouridine synthase TruA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.12" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298234.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001536"/>
    <dbReference type="EnsemblBacteria" id="EEZ40510">
        <property type="protein sequence ID" value="EEZ40510"/>
        <property type="gene ID" value="VDA_001536"/>
    </dbReference>
    <dbReference type="GeneID" id="57342408"/>
    <dbReference type="eggNOG" id="COG0101">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1075262at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106029">
        <property type="term" value="F:tRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031119">
        <property type="term" value="P:tRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02570">
        <property type="entry name" value="PseudoU_synth_EcTruA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.660">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00171">
        <property type="entry name" value="TruA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001406">
        <property type="entry name" value="PsdUridine_synth_TruA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020097">
        <property type="entry name" value="PsdUridine_synth_TruA_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020095">
        <property type="entry name" value="PsdUridine_synth_TruA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11142">
        <property type="entry name" value="PTHR11142"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01416">
        <property type="entry name" value="PseudoU_synth_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001430">
        <property type="entry name" value="tRNA_psdUrid_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00071">
        <property type="entry name" value="hisT_truA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="PseudoU_synth_1" evidence="8">
        <location>
            <begin position="8"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="PseudoU_synth_1" evidence="8">
        <location>
            <begin position="144"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4 5">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4 6">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001430-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001430-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ40510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="261" mass="29600" checksum="945EB93A4D88E9B8" modified="2010-01-19" version="1">MRIALGIEYDGAKYFGWQRQREVDSVQERLEKALAKIANEPVDVFCAGRTDAGVHGTGQVVHFDVNVNRKMAAWTMGVNAHLPSDIAVRWAAEVSDDFHARFTATARRYRYVIYNHALRPAILSSGVSHYHGDLDEKKMHEAGQYLLGENDFTSFRAVHCQSRSPWRNLMHLNVSRQGNYVIIDIKANAFVHHMVRNITGSLIKVGRGEEKPEWIKWLLEQKDRTLAGATAKAEGLYLVDVDYPQEFNLPRVPLGPLFLAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWU6</accession>
    <name>D0YWU6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Dihydrofolate synthase/folylpolyglutamate synthase</fullName>
            <ecNumber evidence="6">6.3.2.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Folylpoly-gamma-glutamate synthetase-dihydrofolate synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Folylpolyglutamate synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">VDA_001538</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>(6R)-5,10-methylenetetrahydrofolyl-(gamma-L-Glu)(n) + ATP + L-glutamate = (6R)-5,10-methylenetetrahydrofolyl-(gamma-L-Glu)(n+1) + ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:51912"/>
            <dbReference type="Rhea" id="RHEA-COMP:13257"/>
            <dbReference type="Rhea" id="RHEA-COMP:13258"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:136572"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.17"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>10-formyltetrahydrofolyl-(gamma-L-Glu)(n) + ATP + L-glutamate = 10-formyltetrahydrofolyl-(gamma-L-Glu)(n+1) + ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:51904"/>
            <dbReference type="Rhea" id="RHEA-COMP:13088"/>
            <dbReference type="Rhea" id="RHEA-COMP:14300"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:134413"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.17"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>7,8-dihydropteroate + ATP + L-glutamate = 7,8-dihydrofolate + ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:23584"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17839"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57451"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.12"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 7,8-dihydrofolate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the folylpolyglutamate synthase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.12" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298238.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001538"/>
    <dbReference type="EnsemblBacteria" id="EEZ40512">
        <property type="protein sequence ID" value="EEZ40512"/>
        <property type="gene ID" value="VDA_001538"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0285">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1232874at2"/>
    <dbReference type="UniPathway" id="UPA00077">
        <property type="reaction ID" value="UER00157"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008841">
        <property type="term" value="F:dihydrofolate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004326">
        <property type="term" value="F:tetrahydrofolylpolyglutamate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001645">
        <property type="entry name" value="Folylpolyglutamate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018109">
        <property type="entry name" value="Folylpolyglutamate_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11136">
        <property type="entry name" value="PTHR11136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001563">
        <property type="entry name" value="Folylpolyglu_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01499">
        <property type="entry name" value="folC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01011">
        <property type="entry name" value="FOLYLPOLYGLU_SYNT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01012">
        <property type="entry name" value="FOLYLPOLYGLU_SYNT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="13 15" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase_M" evidence="14">
        <location>
            <begin position="54"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00000809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00002714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00019357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR001563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEZ40512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="422" mass="45908" checksum="E99100E9019DB7F9" modified="2010-01-19" version="1">MSGLTAPSAMAPLATWLTYLEQLHTSAIDLGLDRVQAVAQKAKLTKPAPTVITVAGTNGKGSTCAMLESILMQAGYSVGVYSSPHLIRYNERVRINGKELDDSEHSQAFASVEQQRGEISLSLFEFGTLSALTLFKQHQVDVVVLEVGLGGRLDATNIVDHDVTVITSLAIDHVDWLGDDINVIGYEKAGIFRTNKPAICGQPHPPATVAAHADDIGAELFQVGYQFDYKVDEEVQTWSWHSGAFDLVDLPIPSLPLPNAATALMALGASELKITDEHIVVGLKVASLPGRMERVQEQPLIIMDVAHNPHSANYFANQLTKLKQREGINKVHAVVAMLHDKDIASTIAEMQDVVDCWYPASLEGPRAAKADEIVAHLSVPCQMFNKPIEAFNQALTQVDVDEMVIVFGSFYTVGQISDYLKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWW2</accession>
    <name>D0YWW2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Lon protease</fullName>
            <ecNumber evidence="5 6">3.4.21.53</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">ATP-dependent protease La</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">lon</name>
        <name evidence="13" type="ORF">VDA_001551</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6 9">
            <text>Hydrolysis of proteins in presence of ATP.</text>
            <dbReference type="EC" id="3.4.21.53"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5 6">Homohexamer. Organized in a ring with a central cavity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="induction">
        <text evidence="5">By heat shock.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 6 9 10">Belongs to the peptidase S16 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.53" evidence="5 6"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298261.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001551"/>
    <dbReference type="MEROPS" id="S16.001"/>
    <dbReference type="EnsemblBacteria" id="EEZ40525">
        <property type="protein sequence ID" value="EEZ40525"/>
        <property type="gene ID" value="VDA_001551"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0466">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="128102at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034605">
        <property type="term" value="P:cellular response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006515">
        <property type="term" value="P:protein quality control for misfolded or incompletely synthesized proteins"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01973">
        <property type="entry name" value="lon_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027543">
        <property type="entry name" value="Lon_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004815">
        <property type="entry name" value="Lon_bac/euk-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008269">
        <property type="entry name" value="Lon_proteolytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027065">
        <property type="entry name" value="Lon_Prtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003111">
        <property type="entry name" value="Lon_prtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046336">
        <property type="entry name" value="Lon_prtase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008268">
        <property type="entry name" value="Peptidase_S16_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10046">
        <property type="entry name" value="PTHR10046"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05362">
        <property type="entry name" value="Lon_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02190">
        <property type="entry name" value="LON_substr_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001174">
        <property type="entry name" value="Lon_proteas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00464">
        <property type="entry name" value="LON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00763">
        <property type="entry name" value="lon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51787">
        <property type="entry name" value="LON_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51786">
        <property type="entry name" value="LON_PROTEOLYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01046">
        <property type="entry name" value="LON_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword evidence="5 6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 5 6" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0720">Serine protease</keyword>
    <keyword evidence="4 5" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="Lon N-terminal" evidence="12">
        <location>
            <begin position="11"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="Lon proteolytic" evidence="11">
        <location>
            <begin position="591"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 7 9">
        <location>
            <position position="678"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 7 9">
        <location>
            <position position="721"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 8">
        <location>
            <begin position="355"/>
            <end position="362"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR001174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001174-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001174-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ40525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="787" mass="87839" checksum="BB942BF94D1B2B8A" modified="2010-01-19" version="1">MNLERSERLEIPVLPLRDVVVYPHMVIPLFVGREKSIRCLEAAMDNNKQILLVAQKEAATDEPSISDLYDVGTVATILQLLKLPDGTVKVLVEGQQRAKVEHLMDDDFFVAEAEYLVTPEMDEREQEVLVRTAINQFDGFVKLNKKIPPEVLTSLNGIDEAARLADTIAAHMPLKLADKQKVLEIVDITERLEFLMAMMESEIDLLQVEKRIRGRVKKQMEKSQREYYLNEQMKAIQKELGDLDDAPDEFEALKAKIDESKMPAEAKEKTEQELQKLKMMSPMSAEATVVRGYIDWMLNVPWHKRSKVKKDLAKAEEILNSDHYGLERVKERILEYLAVQSRVNKLKGPILCLVGPPGVGKTSLGQSIAAATGRKYVRMALGGVRDEAEIRGHRRTYIGSMPGKLIQKMAKVGVKNPLFLLDEIDKMSSDMRGDPASALLEVLDPEQNNAFNDHYLEVDYDLSDVMFVATSNSMNIPGPLLDRMEVIRLSGYTEDEKLNIAKRHLLDKQIKRNGLKPGEVDVDDSALIGIIRYYTREAGVRGLEREISKLCRKAVKEILLNKDVKTVSISQDNLKDYLGVQRFDYGKADDSNRVGQVVGLAWTEVGGDLLTIETESMPGKGKLTYTGSLGDVMQESIQAAMTVVRTRAERLGIASDFYEKRDIHVHVPEGATPKDGPSAGIAMCTALVSSLTGNPVRADVAMTGEITLRGEVLPIGGLKEKLLAAHRGGIKTVLIPKENERDLEEIPANVIADLDVRPVRWIDEVLTIALQNHPEGIELVRAQNSDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX33</accession>
    <name>D0YX33_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Vitamin B12 import ATP-binding protein BtuD</fullName>
            <ecNumber evidence="3">7.6.2.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Vitamin B12-transporting ATPase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">btuD</name>
        <name evidence="6" type="ORF">VDA_001889</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>an R-cob(III)alamin(out) + ATP + H2O = ADP + an R-cob(III)alamin(in) + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17873"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:140785"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.6.2.8"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">The complex is composed of two ATP-binding proteins (BtuD), two transmembrane proteins (BtuC) and a solute-binding protein (BtuF).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ABC transporter superfamily. Vitamin B12 importer (TC 3.A.1.13.1) family.</text>
    </comment>
    <dbReference type="EC" id="7.6.2.8" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001889"/>
    <dbReference type="EnsemblBacteria" id="EEZ40857">
        <property type="protein sequence ID" value="EEZ40857"/>
        <property type="gene ID" value="VDA_001889"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4138">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015420">
        <property type="term" value="F:ABC-type vitamin B12 transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01005">
        <property type="entry name" value="BtuD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023693">
        <property type="entry name" value="ABC_transptr_BtuD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 3 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-1278">Translocase</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="4"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3 4">
        <location>
            <begin position="32"/>
            <end position="39"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="254" mass="27840" checksum="FA920685FC1132D1" modified="2010-01-19" version="1">MMLLHAKNLALPPRLLPMSFSIKGGDIVHLIGPNGSGKSTVMSLLSGLEIGQGDVFLDECSVAQLDLTSLAHIRSYLTQQDKPAFAMRVYQYMSLTIAMFADLTDKQVNTAVDEIANKLNISDKLTRNIQSLSGGEWQRVRIATALLQVDSRINPDAKLLLLDEPAAALDVGQEAALYRILRQVADQGIAVVVANHDLNRTLREADTVLVLKNGSCVAKGAPKQVMTESLLHRVFQTPIKRIVHQGQDCLLFME</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX98</accession>
    <name>D0YX98_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001957</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299014.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001957"/>
    <dbReference type="EnsemblBacteria" id="EEZ40925">
        <property type="protein sequence ID" value="EEZ40925"/>
        <property type="gene ID" value="VDA_001957"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1136">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1181903at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="223" mass="24622" checksum="F39A010BB7DFEEFC" modified="2010-01-19" version="1">MLRLAQLCKGYQDGSEYHSVLQGAELNLERGAQLALMGESGSGKSTLLNLIAGLDSCDAGEIWLGDTPIHAISERQRALFRRNNIGLVFQQFNLLPTITIADNIRFCRQLKGLPESPDLWRQIISALDLMSLLDRFPEEVSGGQQQRAAIARALYMEPQILLADEPTGSLDERNAGAVIRLLTGLCQKLQCTLLLVTHSEQVSSQMHGCIRLQGGQLHVKPRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXM2</accession>
    <name>D0YXM2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">D-alanine-D-alanine ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001763</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298651.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001763"/>
    <dbReference type="EnsemblBacteria" id="EEZ40731">
        <property type="protein sequence ID" value="EEZ40731"/>
        <property type="gene ID" value="VDA_001763"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0189">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1086102at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="354" mass="40438" checksum="DE1B4837302685F8" modified="2010-01-19" version="1">MKILFKNKSISWFEFLPSWVMYLPVAVYCLYLSIRYKHWALPLIANPGIALSGMVGEEKSAVFKQLGTKGKAKVEPYIVCIKQIDLKLDHYLAQLEGANLSFPVVAKPDIGCRGAGVKLINSPEQLHAYINNYPNHQQFLLQKKADWPHEAGIFYVRFPNQELGFILSITLKILPTIIGDGINSIQQLIEQDPRAQHLTHLYFPALSQRLPEILPKGEILELVFTGNHCRGAIFKDGNQFITDQLNLAMNEILLDMDGFYYGRLDIKFKDLDSLQKGENFSILEINGASSEAAHIWDSNGTFFPAIKMLCQQYKILYQIGDLHRRNGYPLPSLKHLLIAWKKERALVQDYQQLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXP1</accession>
    <name>D0YXP1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001744</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298613.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001744"/>
    <dbReference type="EnsemblBacteria" id="EEZ40712">
        <property type="protein sequence ID" value="EEZ40712"/>
        <property type="gene ID" value="VDA_001744"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5032XSE">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1968186at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021457">
        <property type="entry name" value="DUF3108"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11306">
        <property type="entry name" value="DUF3108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019210" evidence="1">
        <location>
            <begin position="21"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="250" mass="28993" checksum="8A76538B56AA4510" modified="2010-01-19" version="1">MKLAFYFLLSLFVLPSVAHASSGIQSTSAITPFSQYHQCDKRLNYDVYFHGQRIGNYNRHIQWQDAFKATVTTTGKANVLLTKSTLNMTSHLYWSDKKQQFVSQGYERKIKGLLSGKVTAQFLRDGEQSKLVVDKTQLQFASKDFMPILDGDAIGAQMRYLILKGEKSFEFNFQDTDEVNHYYFIVKGEEMINTRFGKLKTIRVEQTRKKDRKLVLWFAPSIDYQLVRATYHRKLLDLEAVLVSKNFSCH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXQ9</accession>
    <name>D0YXQ9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002072</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299348.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002072"/>
    <dbReference type="EnsemblBacteria" id="EEZ41040">
        <property type="protein sequence ID" value="EEZ41040"/>
        <property type="gene ID" value="VDA_002072"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1626">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="70058at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="838" mass="95193" checksum="5A14B8685A6D5FC9" modified="2010-01-19" version="1">MQKKILAILISATFTLVGCNSSDNENNTQTNPPIITPQPEGENGIQPEPPVPDPEDDIIINSTDYQLSLDTAKTMIFANASFYGKGHESHWHNKNTIVGFGYKNQTSDKDGIGWFIEIPEKTELELTALVENTFIQEDGSNGGMLRVEVFDAEDLMRNKLISGIDAQWKVYTKKDNSKDNWGLVEDKLGTVTIPNEGKYLIILRAVQNGSNPNGEIYERNVSMLAEMKLTGKYAENIEQLKIPETRGRYFTWKKEYIPEDLPTFESSKDKLPKPILDGNPEWVNLYWNTWKFAFEQLRTVKATNTTFVSNYIDEAFSNDLFQWDIQMMIEFWKYSNETFNAIATQDNFYRAQNYNGMIHRMLNEITGDDHGQNDAQQTNPPIFAWAELNWATITGDKTRFEYVIPAIAKQLEYIENAHAEPKNKKDKHFLYWNNGQGNGLDSLPRANGPYETKDVGSVDMSVQVANEYFSLAKMSEMIGNENDANRFREKGLFIAEKINQLWDDNANFYVDINSDKSTFLDKATGEPVLTLAGSWPLLFGDEIISDNSIRAGLMVEKLFSPDYFFEPFPLPVLSKNHSQYTPGEYDMGGVMTPTAMITMAGLRKQGYIHEASVLGEKILNAVNEIFRGGTHYWGNHVLTYPEWKDKRICTIWEMYKPTKSLDNHGGIWDTNEEIYYHNGAENGSRSVRPQFVGWSGIYPINTLIDHVIGLEANALENQITWNLRRTDRHGIEQFKVGDTFVDLIANERNVGDAVTITAKSSNKDIKLTVKHLQDDSDNSSIVKKTITLKAGQPITFTVKGSGIASAKHSYPVYDSSRFKLNENCANYSDLIKENYPIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY35</accession>
    <name>D0YY35_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hypothetical intracellular protease/amidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002198</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299634.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002198"/>
    <dbReference type="EnsemblBacteria" id="EEZ41166">
        <property type="protein sequence ID" value="EEZ41166"/>
        <property type="gene ID" value="VDA_002198"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0693">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1421548at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DJ-1_PfpI" evidence="1">
        <location>
            <begin position="2"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="198" mass="21858" checksum="533CFDF4014473C1" modified="2010-01-19" version="1">MKKVILFLCQGLEEYEASVFTDAFGWTTTYGLEPIELVTVGLRPKVKCAWNFTIEPEYQLSEIDINDFDALAIPGGMSRSGFYEDAYDERLLSLIRDFDSKGKLIASVCVGALPIAKSGVLNGRNGTTYHLSKKRQTQMEEMGVNVIQAPIVIDKNIITSRSPSAAMDVAFNVVEMLTSTANLERIKEGMGFVEKTGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY39</accession>
    <name>D0YY39_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002202</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41170">
        <property type="protein sequence ID" value="EEZ41170"/>
        <property type="gene ID" value="VDA_002202"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="37" mass="4278" checksum="F5EA6BEE6CE0E358" modified="2010-01-19" version="1">MGVSSNKQGYDKPSFKVSYAELEMVFPYHQKVNVKQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY50</accession>
    <name>D0YY50_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hydrogenase maturation protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_002213</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase A31 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299660.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002213"/>
    <dbReference type="EnsemblBacteria" id="EEZ41181">
        <property type="protein sequence ID" value="EEZ41181"/>
        <property type="gene ID" value="VDA_002213"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0680">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1858718at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008047">
        <property type="term" value="F:enzyme activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016485">
        <property type="term" value="P:protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004419">
        <property type="entry name" value="Pept_A31_hyd_express"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023430">
        <property type="entry name" value="Pept_HybD-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000671">
        <property type="entry name" value="Peptidase_A31"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30302">
        <property type="entry name" value="PTHR30302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01750">
        <property type="entry name" value="HycI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00446">
        <property type="entry name" value="HYDRGNUPTAKE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53163">
        <property type="entry name" value="SSF53163"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00140">
        <property type="entry name" value="hupD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00072">
        <property type="entry name" value="hydrog_prot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0533">Nickel</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="181" mass="20215" checksum="56C0188270447AE8" modified="2010-01-19" version="1">MKILLLGIGNVLYADEGVGVHFVNYLSENYQFHHPEHQIDLVDGGTLAHSLIPTLTQYDHLVVVDTVNAADVEPGEVYFFDFDKAPAEIDWQGSAHEVEMLQTLIMMEMVGDRPKTYVLGITPTVLEPMHLGLTSRIHAAIPTMEKAIIQHLQSLGVDCQRINNIEINDLIPTAYKRGVEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY65</accession>
    <name>D0YY65_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CMD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002228</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299693.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002228"/>
    <dbReference type="EnsemblBacteria" id="EEZ41196">
        <property type="protein sequence ID" value="EEZ41196"/>
        <property type="gene ID" value="VDA_002228"/>
    </dbReference>
    <dbReference type="GeneID" id="57341618"/>
    <dbReference type="eggNOG" id="COG2128">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1893149at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051920">
        <property type="term" value="F:peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004675">
        <property type="entry name" value="AhpD_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003779">
        <property type="entry name" value="CMD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02627">
        <property type="entry name" value="CMD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="SSF69118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00778">
        <property type="entry name" value="ahpD_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CMD" evidence="1">
        <location>
            <begin position="38"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="194" mass="22082" checksum="E30FBF7A85FBFA71" modified="2010-01-19" version="1">MRIQAKKKYSIFIRPLLWLQERHYGSVLNPAKLWGRKPTLFWLVAGFFGYLDRSKSPLSPVLRSLVCVRVSQLNDCAFCVDANGMKLAERCNSVDKIKQLAHWQESELFSDQERVVLEYTEAMTITGSKVTEEMIATLSQWFNEDSLVELTALIAFQNLSAKFNTALDVPAQGFCSLPIQPKSEQEKSQDNSDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY89</accession>
    <name>D0YY89_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UPF0319 protein VDA_002252</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002252</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the UPF0319 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299737.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002252"/>
    <dbReference type="EnsemblBacteria" id="EEZ41220">
        <property type="protein sequence ID" value="EEZ41220"/>
        <property type="gene ID" value="VDA_002252"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3110">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1877964at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00789">
        <property type="entry name" value="UPF0319"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018635">
        <property type="entry name" value="UPF0319"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38108">
        <property type="entry name" value="PTHR38108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09829">
        <property type="entry name" value="DUF2057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5009009104" description="UPF0319 protein VDA_002252" evidence="2">
        <location>
            <begin position="22"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="209" mass="22892" checksum="7AE909A9A6BA35FC" modified="2010-01-19" version="1" precursor="true">MKLHSLFLVLAAAGFSCSTLADVTVNLPNNAELVLVNGASAKGNDPITLPNGENQIALRYNGNFRQGGNFQAFESDVVIMKFAGDNTTYTLTMPQIRNEQQADNFNENPQISLKNAQGNNISFEQDKLMKKGFQIGRNYEVEIAKYNQTNGPAALASLPSVVVLPATINPADYPATQKGKAQETAAKMLNYWWSQADATTREAFKKKIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYA3</accession>
    <name>D0YYA3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Diacylglycerol O-acyltransferase</fullName>
            <ecNumber evidence="5">2.3.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">VDA_002266</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 1,2-diacyl-sn-glycerol + an acyl-CoA = a triacyl-sn-glycerol + CoA</text>
            <dbReference type="Rhea" id="RHEA:10868"/>
            <dbReference type="ChEBI" id="CHEBI:17815"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:64615"/>
            <dbReference type="EC" id="2.3.1.20"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Glycerolipid metabolism; triacylglycerol biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the long-chain O-acyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.20" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299760.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002266"/>
    <dbReference type="EnsemblBacteria" id="EEZ41234">
        <property type="protein sequence ID" value="EEZ41234"/>
        <property type="gene ID" value="VDA_002266"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="279287at2"/>
    <dbReference type="UniPathway" id="UPA00276">
        <property type="reaction ID" value="UER00929"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00282"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004144">
        <property type="term" value="F:diacylglycerol O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006071">
        <property type="term" value="P:glycerol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019432">
        <property type="term" value="P:triglyceride biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014292">
        <property type="entry name" value="Acyl_transf_WS/DGAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045034">
        <property type="entry name" value="O-acyltransferase_WSD1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009721">
        <property type="entry name" value="O-acyltransferase_WSD1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004255">
        <property type="entry name" value="O-acyltransferase_WSD1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31650">
        <property type="entry name" value="PTHR31650"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03007">
        <property type="entry name" value="WES_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06974">
        <property type="entry name" value="WS_DGAT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02946">
        <property type="entry name" value="acyl_WS_DGAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0319">Glycerol metabolism</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="WES_acyltransf" evidence="10">
        <location>
            <begin position="7"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="WS_DGAT_C" evidence="11">
        <location>
            <begin position="310"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="502"/>
            <end position="529"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF06974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ41234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="560" mass="62295" checksum="87865AF10F25FF8A" modified="2010-01-19" version="1">MPSVSLLDFSFLFFESQQTPMHVIGLVVLDPPKEHKHHYAQDLYAALLQETKVSAPFNWRLQWSITGKPSWQQLKSVNLDDHLRITMLPSPGTEEQLQKVVGRIHGQTLDRSKPMWEVWIIGGLQDDKVALVLKIHHSMADGIKASSIFNRSCGLTPEESFNKPMWQFDLTKTAKERAQEKHLADLVTKAAIQATRQLSLIPSMFRLGSKLALKALNIADCDLKLPFTAPKTILNLSPKRSRAVSTGKFSFAQLNHIRSITGASVNDVLFAISDQALNRYLNDRAVPLRKPLVAMMPINLRKEGDGSKSNRMSIGHVELGKRDLTVLERLETIQRATVDLKNEALNISPDAYVNYSFLVNGVSLISGKFGLNSFVPPASNLLISNVPGQKATAYFMGAKVDAQYPVSLLMPGQTLNITFYSYAGMLHYSLVACNQSLPGFEDIGSYMQEALGDLEAEVMDVAIDAVGEQVSFHDEESLALEMAVVAARESLRPTDSAFDVIYQQKMQRVEELERQLAQLTAALENTIKLDPKLVAVNDEDVKKKVAKPRKQTKKKVELSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYE9</accession>
    <name>D0YYE9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Periplasmic protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002312</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299841.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002312"/>
    <dbReference type="EnsemblBacteria" id="EEZ41280">
        <property type="protein sequence ID" value="EEZ41280"/>
        <property type="gene ID" value="VDA_002312"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2200">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="151"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="194"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="218"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="271"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="2">
        <location>
            <begin position="449"/>
            <end position="688"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="688" mass="79022" checksum="16EB7B47B2506ABD" modified="2010-01-19" version="1">MIKYFLSVRQETNLQKLGYVVLSFILILGSFEVSSFSYSNVTSIQQFSLPSGVMVALVYLLGSSAIMGIFASLLCYYTFFKYIDSGAAYVYTLILTITLILSLSFIKWVRYHNHSTKLIFGFFVFLLPALSSLTLVIFAPNSFRFEFTLNLFLADSISILLLAPLIGTLFLLICNNKNIKEYIIDDIYEIKKNLLTKTVLIGFIILVMLFGVLQPISYMAYILLMPLLIVAVVVIPVICQIILINISYFILLSGCYTNNNDIHFINNKLTIFYMMAIIVFIILDFKVSLKKEIKDHKKHVFIDTCSTLGTYQKLESDSQNKTDFIIAAIDLQSLFKFPIKKRETIIIMIAKLLKEKTGLYESAYILYDLSSLVILLDDNSRALSKLKSFSEIVNDTLEQHNINYKLGKVFYIRCENYTRLKVMINHLHINSKLADPLSEQKLINCENNEINDYISFLSYIDDKQINIAYQNYSSTQGGERCFEVLSRFNFNKNFLNPERVFTFAKRLNRLEALEQKVSRKALNHIKELPESDYQYASINFSPDFLCSTRSINYFINQLELLEISPEKICIELVETGEIEDVTALVDNLNILKSIGVKIALDDFGKGHATYEKLFNLPIDIVKIDGSLVHFCDQDLMKQLIIENVCKISSMRNIKVVAECVETPEEREILEQLHIDYLQGYLIHKPALF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYH8</accession>
    <name>D0YYH8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative amino acid transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_002341</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299923.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002341"/>
    <dbReference type="EnsemblBacteria" id="EEZ41309">
        <property type="protein sequence ID" value="EEZ41309"/>
        <property type="gene ID" value="VDA_002341"/>
    </dbReference>
    <dbReference type="GeneID" id="57341464"/>
    <dbReference type="eggNOG" id="COG0531">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="527053at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="122"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="155"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="196"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="236"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="284"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="337"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="361"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="407"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="438"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="464" mass="50757" checksum="AEB71E2484B89BCC" modified="2010-01-19" version="1">MGNIAKSAVKLSVFSVIMITVTSVDSIRNLPGAALFGSHAISYFLLAGFCFFVPTALVCAELSTTYPKQGGVYLWGKETLGHNFGFVTVWYQYAENIVYYPPLISFIVATGTYPFFPHLAENNIFMLVMINVIFWALTIVNIYGLRLSSIITNVFGTFGLIFPILLIIALGAYWTYTNPESSHISLRHASDWLPDFSQSGVGASFTAVVLSLTGIEITTAYASEVKNPQKAYPKALLISTVLILISLTACSLSIAAVVSSNHSSLSEGVILAFKTFFEDLNMPYLLPIIALAIVFGSLASLNNWIIAPTKSLHVAAQDKFMPIRLAKENENQAPVPLLLLQGAIVSLLSLVFILVPNVNQGMWLLNILMTQLYMVMYICIFISFLVSRRKHKDIERPFRVPGGKFGMIVAAVLGLFSCVVTIIVSFDVPAGISKTTGAYALIIGFIVFSLPAIFAIKYRKKHAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYI4</accession>
    <name>D0YYI4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Ribokinase</fullName>
            <shortName evidence="10">RK</shortName>
            <ecNumber evidence="3 10">2.7.1.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">rbsK</name>
        <name evidence="13" type="ORF">VDA_002347</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>ATP + D-ribose = ADP + D-ribose 5-phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13697"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:47013"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.15"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="10">Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.</text>
    </comment>
    <comment type="activity regulation">
        <text evidence="10">Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.</text>
    </comment>
    <comment type="pathway">
        <text evidence="10">Carbohydrate metabolism; D-ribose degradation; D-ribose 5-phosphate from beta-D-ribopyranose: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the carbohydrate kinase pfkB family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.15" evidence="3 10"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299929.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002347"/>
    <dbReference type="EnsemblBacteria" id="EEZ41315">
        <property type="protein sequence ID" value="EEZ41315"/>
        <property type="gene ID" value="VDA_002347"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0524">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1030724at2"/>
    <dbReference type="UniPathway" id="UPA00916">
        <property type="reaction ID" value="UER00889"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004747">
        <property type="term" value="F:ribokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019303">
        <property type="term" value="P:D-ribose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
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        <property type="match status" value="1"/>
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    <dbReference type="PRINTS" id="PR00990">
        <property type="entry name" value="RIBOKINASE"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="10" id="KW-0119">Carbohydrate metabolism</keyword>
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    <keyword evidence="8 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 10" id="KW-0630">Potassium</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="12">
        <location>
            <begin position="4"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="13"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="41"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="254"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="142"/>
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        <ligand>
            <name>substrate</name>
        </ligand>
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    <feature type="binding site" evidence="10">
        <location>
            <position position="186"/>
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        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
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        <location>
            <begin position="222"/>
            <end position="227"/>
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        <location>
            <position position="248"/>
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        <ligand>
            <name>K(+)</name>
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            <position position="250"/>
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            <position position="284"/>
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        <location>
            <position position="287"/>
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        <location>
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            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
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        <source>
            <dbReference type="RuleBase" id="RU003704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ41315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="307" mass="32663" checksum="0E2077FF3E77AFC3" modified="2010-01-19" version="1">MNQKKIVVLGSSSQDHTVQSSHLPQMGETVMGHRHIMASGGKGANQAVAAARLGAPVTFIACMGNDGFAHDTLPKFSEDGINTDHIHICDNENTGIALILVDDEGRNCISISPNANGRLNAEVVDSHAEVIRNTDYLLLQLETPQDGIDRAVELAKQANATVILNPAPARPLSDHLLSQLDLITPNETEAEILTGIKVVDEKTAEQAAQAFIAKGVKEVIITMGKQGAYLYRQGQGKLIPGHRVNATDTTAAGDTFNGALLVALSQGADLEEAILFAHKASAISVTRMGAQTSIPYLKELDAFNFVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYV6</accession>
    <name>D0YYV6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Histidine biosynthesis bifunctional protein HisB</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="9">Histidinol-phosphatase</fullName>
                <ecNumber evidence="9">3.1.3.15</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="9">Imidazoleglycerol-phosphate dehydratase</fullName>
                <shortName evidence="9">IGPD</shortName>
                <ecNumber evidence="9">4.2.1.19</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="9" type="primary">hisB</name>
        <name evidence="10" type="ORF">VDA_002469</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + H2O</text>
            <dbReference type="Rhea" id="RHEA:11040"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57766"/>
            <dbReference type="ChEBI" id="CHEBI:58278"/>
            <dbReference type="EC" id="4.2.1.19"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>H2O + L-histidinol phosphate = L-histidinol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14465"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57699"/>
            <dbReference type="ChEBI" id="CHEBI:57980"/>
            <dbReference type="EC" id="3.1.3.15"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 6/9.</text>
    </comment>
    <comment type="pathway">
        <text evidence="9">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 8/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">In the N-terminal section; belongs to the histidinol-phosphatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.15" evidence="9"/>
    <dbReference type="EC" id="4.2.1.19" evidence="9"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002469"/>
    <dbReference type="EnsemblBacteria" id="EEZ41437">
        <property type="protein sequence ID" value="EEZ41437"/>
        <property type="gene ID" value="VDA_002469"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0131">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0241">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00011"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004401">
        <property type="term" value="F:histidinol-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004424">
        <property type="term" value="F:imidazoleglycerol-phosphate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07914">
        <property type="entry name" value="IGPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01022">
        <property type="entry name" value="Bifunc_HisB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00076">
        <property type="entry name" value="HisB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006549">
        <property type="entry name" value="HAD-SF_hydro_IIIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020566">
        <property type="entry name" value="His_synth_bifunc_HisB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005954">
        <property type="entry name" value="HisB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006543">
        <property type="entry name" value="Histidinol-phos"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038494">
        <property type="entry name" value="IGPD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000807">
        <property type="entry name" value="ImidazoleglycerolP_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020565">
        <property type="entry name" value="ImidazoleglycerP_deHydtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013954">
        <property type="entry name" value="PNK3P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23133">
        <property type="entry name" value="PTHR23133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00475">
        <property type="entry name" value="IGPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08645">
        <property type="entry name" value="PNK3P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01662">
        <property type="entry name" value="HAD-SF-IIIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01261">
        <property type="entry name" value="hisB_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01656">
        <property type="entry name" value="Histidinol-ppas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00954">
        <property type="entry name" value="IGP_DEHYDRATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00955">
        <property type="entry name" value="IGP_DEHYDRATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="9 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 9 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 9" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Histidinol-phosphatase" evidence="9">
        <location>
            <begin position="1"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Imidazoleglycerol-phosphate dehydratase" evidence="9">
        <location>
            <begin position="168"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9">
        <location>
            <position position="10"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="9">
        <location>
            <position position="12"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="12"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ41437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="356" mass="39695" checksum="937C979AFEAA277E" modified="2010-01-19" version="1">MSQEKILFIDRDGTLIVEPPIDFQVDRLDKLQLEPYVIPALLELQNAGYQLVMVTNQDGLGTESYPQADFDAPHNMMMDIFTSQGVKFSDVLICPHFDHENCSCRKPKLGLVKTYLQQGRVDFSQSAVIGDRPTDLQLAENMAIRGIQYHPQQMGWQQIVKDLTSNPRIAEVIRTTKETDIHVKVNLDQSGGNQISTGLGFFDHMLDQIATHGGFQLEVNVAGDLYIDDHHSIEDTALALGDALRKALGDKRGIGRFGFSLPMDECLAQCALDLSGRPYLKFDATFSREQVGDLSTEMVEHFFRSLTDTLACTLHLSSSGQNDHHIIESLFKAFGRTLRQAIKVEGNELPSSKGVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ07</accession>
    <name>D0YZ07_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Inosine-guanosine kinase</fullName>
            <ecNumber evidence="2">2.7.1.73</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002520</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.1.73" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002520"/>
    <dbReference type="EnsemblBacteria" id="EEZ41488">
        <property type="protein sequence ID" value="EEZ41488"/>
        <property type="gene ID" value="VDA_002520"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0524">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106366">
        <property type="term" value="F:guanosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008906">
        <property type="term" value="F:inosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="1">
        <location>
            <begin position="25"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="368" mass="41243" checksum="203759B5E991C8F1" modified="2010-01-19" version="1">MITDEMAEALYRELKDNDLITHEFAGGTIGNTLHNYSVLADDKSVLLGVMSKDIEIGSYAYRYLCNTSSRMDMNFLQPVTGPIGRCFALISPEGERTFAINEGRMNQLHPDSIPESVFENASALVLTAYLVRCKEGDPMPAATMRAIEYAKKYDVPVVLTLGTKFVIQDDPQWWRDFLRDNVTVVAMNEDEGEALTGESDPLVAADKALDWVDLVLCTAGPVGLYMAGYTEDDAKRQTSLPLLPGDIAEFNQYEFSRPMLKEQCEQPIKVYSHIAPYMGGPERIKNTNGAGDGALSALLHDMSANRYHKENVPNSSKHQHSFLTYSSFSQICLYANRVSYEVLAQYSPRLSRGLPEREDSLEEAYWER</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ32</accession>
    <name>D0YZ32_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002545</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300296.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002545"/>
    <dbReference type="EnsemblBacteria" id="EEZ41513">
        <property type="protein sequence ID" value="EEZ41513"/>
        <property type="gene ID" value="VDA_002545"/>
    </dbReference>
    <dbReference type="GeneID" id="57341220"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1661500at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="312" mass="34847" checksum="B64468A6140ED2B0" modified="2010-01-19" version="1">MKALNDLQVFIEASRMGSFSKVANSMGITPAAVSAAIKRLEEQVGFPLFIRSTRHLRLTNEGEIFCDKASMAVNILQDGLDQIANDRNAFSGKLHITAPSDFGRNLLLTWIAEFQEIYPDITIKLELSDKVADIYSQPVDIAIRYGQPADSNLVAISLCQLNEGITCATPEYIAANPTITEPMDLLAHNCLCFMVADTLYNKWQFSCDNRSEIVHVSGNMTGNDSDMIHRLALKGKGIIHTSLMDLSEDIIAGRLVPIFPQWRGFSAPLYMVCADRRLLNPTIRKFQEFIKEKCCQQRKRVLTALGNEQVTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ44</accession>
    <name>D0YZ44_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator AsnC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002557</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002557"/>
    <dbReference type="EnsemblBacteria" id="EEZ41525">
        <property type="protein sequence ID" value="EEZ41525"/>
        <property type="gene ID" value="VDA_002557"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1522">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019887">
        <property type="entry name" value="Tscrpt_reg_AsnC/Lrp_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01037">
        <property type="entry name" value="AsnC_trans_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AsnC_trans_reg" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="53" mass="6067" checksum="856BEE9EE3AB9448" modified="2010-01-19" version="1">MAGEYDYMMKVQVADMFAFDKFYKKLVNSVEGLTNVTSTFAMEQLKYTTALPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ47</accession>
    <name>D0YZ47_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">50S ribosomal protein L3 glutamine methyltransferase</fullName>
            <shortName evidence="6">L3 MTase</shortName>
            <ecNumber evidence="6">2.1.1.298</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">N5-glutamine methyltransferase PrmB</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">prmB</name>
        <name evidence="8" type="ORF">VDA_002560</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.</text>
    </comment>
    <comment type="function">
        <text evidence="6">Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-methionine = H(+) + N(5)-methyl-L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42896"/>
            <dbReference type="Rhea" id="RHEA-COMP:10271"/>
            <dbReference type="Rhea" id="RHEA-COMP:10272"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30011"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61891"/>
            <dbReference type="EC" id="2.1.1.297"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-glutaminyl-[ribosomal protein uL3] + S-adenosyl-L-methionine = H(+) + N(5)-methyl-L-glutaminyl-[ribosomal protein uL3] + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:45020"/>
            <dbReference type="Rhea" id="RHEA-COMP:11063"/>
            <dbReference type="Rhea" id="RHEA-COMP:11064"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30011"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61891"/>
            <dbReference type="EC" id="2.1.1.298"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.298" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300328.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002560"/>
    <dbReference type="EnsemblBacteria" id="EEZ41528">
        <property type="protein sequence ID" value="EEZ41528"/>
        <property type="gene ID" value="VDA_002560"/>
    </dbReference>
    <dbReference type="GeneID" id="57341200"/>
    <dbReference type="eggNOG" id="COG2890">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1816476at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102559">
        <property type="term" value="F:protein-(glutamine-N5) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036009">
        <property type="term" value="F:protein-glutamine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018364">
        <property type="term" value="P:peptidyl-glutamine methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02125">
        <property type="entry name" value="L3_methyltr_PrmB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004556">
        <property type="entry name" value="HemK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019874">
        <property type="entry name" value="Release_fac_Glu-N5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017127">
        <property type="entry name" value="Ribosome_L3_Gln-N5_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007848">
        <property type="entry name" value="Small_mtfrase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05175">
        <property type="entry name" value="MTS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037167">
        <property type="entry name" value="Mtase_YfcB_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00536">
        <property type="entry name" value="hemK_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03533">
        <property type="entry name" value="L3_gln_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03534">
        <property type="entry name" value="RF_mod_PrmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MTS" evidence="7">
        <location>
            <begin position="130"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ41528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="310" mass="35504" checksum="989D901636804BC1" modified="2010-01-19" version="1">MDKIFVDEAVNELHTLQDMLRWTVSRFNAANLFYGHGTDNAWDEAVQLVLPTLYLPLDVPSEVRFSRLTSSERHRVVERVIRRINERTPVSYITNKAYFCGMEFFVDERVLVPRSPIGELIENRFEPFLKQEPTRIMDLCTGSGCIGIACAHMFPEAEVDIVDISTDALAVAEQNIQDHGLEQQVTPLRSDLLRDVPKDLYDLIVTNPPYVDQEDMDNLPDEFRHEPELGLAAGSDGLKLVRRILSNAPNYLKEDGVLICEVGNSMVHMEEQYPHIPFTWIEFENGGHGVFMLTRDQLVEFADDFALYRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ88</accession>
    <name>D0YZ88_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Flagellar regulatory protein FleQ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_002601</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300448.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002601"/>
    <dbReference type="EnsemblBacteria" id="EEZ41569">
        <property type="protein sequence ID" value="EEZ41569"/>
        <property type="gene ID" value="VDA_002601"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2204">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="123059at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002197">
        <property type="entry name" value="HTH_Fis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025943">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025944">
        <property type="entry name" value="Sigma_54_int_dom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029995">
        <property type="entry name" value="TR_FlbD/FleR/FlgR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32071:SF21">
        <property type="entry name" value="PTHR32071:SF21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02954">
        <property type="entry name" value="HTH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00158">
        <property type="entry name" value="Sigma54_activat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00676">
        <property type="entry name" value="SIGMA54_INTERACT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00688">
        <property type="entry name" value="SIGMA54_INTERACT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50045">
        <property type="entry name" value="SIGMA54_INTERACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0966">Cell projection</keyword>
    <keyword evidence="10" id="KW-0969">Cilium</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-0282">Flagellum</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Response regulatory" evidence="9">
        <location>
            <begin position="5"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="8">
        <location>
            <begin position="128"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="399"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="407"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="6">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ41569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="486" mass="54065" checksum="1380A91D0FFC1DE0" modified="2010-01-19" version="1">MNQTCVLVVEDDDGLREALIDTLALAGYNWLEANSAEQALLMLKEQSVDIVVSDVQMSGMNGLSLLRSIKLTYPKLPVILMTAFANIEDAVIAMREGAVDYMSKPFAPEVLLNLVGRYAPIKNDLGRAIVADEKSKRLLNLAEKVAKTDANVMVLGPSGSGKEVMSRYIHEHSLRCDGPFVAINCAAIPENMLEATLFGYEKGAFTGAIQACPGKFEQAQGGTILLDEISEMDLSLQAKLLRVLQEREVERLGSRKSIKLNVRVLATSNRDLRQYVEQGQFREDLYYRLNVFPITWPPLAERLGDIAPLAQFFAERHCIKQGLPVPHVSECALKKLCCYNWPGNVRELDNVIQRALILCEEKITHDHILLEGVDWLDADCLQQAICQQQQVSELSESELASDQAAKSVEPEPEDTKKPEDNSKKMIVSCADGLGNELREQEFSIIFDTLMACDGKRKDVAERLGISPRTLRYKLAKMRSAGIEIPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZB6</accession>
    <name>D0YZB6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002629</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300540.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002629"/>
    <dbReference type="EnsemblBacteria" id="EEZ41597">
        <property type="protein sequence ID" value="EEZ41597"/>
        <property type="gene ID" value="VDA_002629"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018701" evidence="1">
        <location>
            <begin position="23"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="63" mass="6538" checksum="C1442D653363856B" modified="2010-01-19" version="1">MKKLVFAVCLGMAVFTSSSVFANGGNSGAGGGFGQTICTLPDGSYGFMPWFACKWKGGESLDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZC4</accession>
    <name>D0YZC4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PTS system glucose-specific IIA component</fullName>
            <ecNumber evidence="4">2.7.1.69</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_002637</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.1.69" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300563.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002637"/>
    <dbReference type="EnsemblBacteria" id="EEZ41605">
        <property type="protein sequence ID" value="EEZ41605"/>
        <property type="gene ID" value="VDA_002637"/>
    </dbReference>
    <dbReference type="GeneID" id="57341107"/>
    <dbReference type="eggNOG" id="COG2190">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1481289at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103111">
        <property type="term" value="F:D-glucosamine PTS permease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008982">
        <property type="term" value="F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001127">
        <property type="entry name" value="PTS_EIIA_1_perm"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00358">
        <property type="entry name" value="PTS_EIIA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00830">
        <property type="entry name" value="PTBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51093">
        <property type="entry name" value="PTS_EIIA_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00371">
        <property type="entry name" value="PTS_EIIA_TYPE_1_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PTS EIIA type-1" evidence="3">
        <location>
            <begin position="39"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="169" mass="18096" checksum="1BE3E7157B084A91" modified="2010-01-19" version="1">MGLFDKLKKLVSDDSSEAGAIEIIAPLSGEIVNIEDVPDVVFAEKIVGDGIAIKPSGNKMVAPVNGTIGKIFETNHAFSIESEDGIELFVHFGIDTVELKGEGFTRIAEEGQTVKVGDTIIEFDLALLEEKAKSTLTPVVISNMDEIKELNKLSGAVTVGETPVLRIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZC9</accession>
    <name>D0YZC9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Periplasmic nitrate reductase</fullName>
            <ecNumber evidence="11">1.9.6.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">napA</name>
        <name evidence="14" type="ORF">VDA_002642</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>2 Fe(II)-[cytochrome] + 2 H(+) + nitrate = 2 Fe(III)-[cytochrome] + H2O + nitrite</text>
            <dbReference type="Rhea" id="RHEA:12909"/>
            <dbReference type="Rhea" id="RHEA-COMP:11777"/>
            <dbReference type="Rhea" id="RHEA-COMP:11778"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16301"/>
            <dbReference type="ChEBI" id="CHEBI:17632"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="1.9.6.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
            <dbReference type="ChEBI" id="CHEBI:60539"/>
        </cofactor>
        <text evidence="11">Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="11">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.9.6.1" evidence="11"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002642"/>
    <dbReference type="EnsemblBacteria" id="EEZ41610">
        <property type="protein sequence ID" value="EEZ41610"/>
        <property type="gene ID" value="VDA_002642"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0243">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030151">
        <property type="term" value="F:molybdenum ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043546">
        <property type="term" value="F:molybdopterin cofactor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050140">
        <property type="term" value="F:nitrate reductase (cytochrome) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008940">
        <property type="term" value="F:nitrate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042128">
        <property type="term" value="P:nitrate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02791">
        <property type="entry name" value="MopB_CT_Nitrate-R-NapA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01630">
        <property type="entry name" value="Nitrate_reduct_NapA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041957">
        <property type="entry name" value="CT_Nitrate-R-NapA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006657">
        <property type="entry name" value="MoPterin_dinucl-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006656">
        <property type="entry name" value="Mopterin_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006963">
        <property type="entry name" value="Mopterin_OxRdtase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027467">
        <property type="entry name" value="MopterinOxRdtase_cofactor_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010051">
        <property type="entry name" value="Periplasm_NO3_reductase_lsu"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04879">
        <property type="entry name" value="Molybdop_Fe4S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00384">
        <property type="entry name" value="Molybdopterin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01568">
        <property type="entry name" value="Molydop_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00926">
        <property type="entry name" value="Molybdop_Fe4S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="SSF50692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01706">
        <property type="entry name" value="NAPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51669">
        <property type="entry name" value="4FE4S_MOW_BIS_MGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00551">
        <property type="entry name" value="MOLYBDOPTERIN_PROK_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6 11" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8 11 12" id="KW-0408">Iron</keyword>
    <keyword evidence="9 11 12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4 11 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 11" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="10 11" id="KW-0534">Nitrate assimilation</keyword>
    <keyword evidence="7 11 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5 11" id="KW-0574">Periplasm</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <keyword evidence="2 11" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5009009106" description="Periplasmic nitrate reductase" evidence="11">
        <location>
            <begin position="22"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S Mo/W bis-MGD-type" evidence="13">
        <location>
            <begin position="33"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Mo-bis(molybdopterin guanine dinucleotide) binding" evidence="11">
        <location>
            <begin position="206"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Mo-bis(molybdopterin guanine dinucleotide) binding" evidence="11">
        <location>
            <begin position="237"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Mo-bis(molybdopterin guanine dinucleotide) binding" evidence="11">
        <location>
            <begin position="256"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Mo-bis(molybdopterin guanine dinucleotide) binding" evidence="11">
        <location>
            <begin position="502"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Mo-bis(molybdopterin guanine dinucleotide) binding" evidence="11">
        <location>
            <begin position="710"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11 12">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11 12">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11 12">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11 12">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
            <dbReference type="ChEBI" id="CHEBI:60539"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
            <dbReference type="ChEBI" id="CHEBI:60539"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
            <dbReference type="ChEBI" id="CHEBI:60539"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
            <dbReference type="ChEBI" id="CHEBI:60539"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="366"/>
        </location>
        <ligand>
            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
            <dbReference type="ChEBI" id="CHEBI:60539"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="370"/>
        </location>
        <ligand>
            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
            <dbReference type="ChEBI" id="CHEBI:60539"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="476"/>
        </location>
        <ligand>
            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
            <dbReference type="ChEBI" id="CHEBI:60539"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="525"/>
        </location>
        <ligand>
            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
            <dbReference type="ChEBI" id="CHEBI:60539"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="552"/>
        </location>
        <ligand>
            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
            <dbReference type="ChEBI" id="CHEBI:60539"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="786"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="794"/>
        </location>
        <ligand>
            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
            <dbReference type="ChEBI" id="CHEBI:60539"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="811"/>
        </location>
        <ligand>
            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
            <dbReference type="ChEBI" id="CHEBI:60539"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEZ41610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="820" mass="92264" checksum="74CC7126D64AC822" modified="2010-01-19" version="1" precursor="true">MKANAAASAAAVAGISLPTSATNLIVSSDETKIKWDKAPCRFCGTGCSVLVGTQNGRVVATQGDPEAPVNKGLNCIKGYFLSKIMYGNDRLQTPMLRMKNGQYDKEGEFTAVSWDHAFDVMAEKWKQALQKQGPSGVGMFGSGQWTVMEGYAASKMMKAGFRSNNIDPNARHCMASAVVGFMRTFGIDEPMGCYDDFEHADAFVLWGSNMAEMHPVLWTRITDRRLSNPHVKVNVLSTYYHRSFELADNGMIFEPQTDLAIANYIANYIIQNDAVNWDFVNKHTHFKRAQTDIGYGLRDDNPLQKKAKNPNSGEMFAMTFDEYKASVAEYTLEKASEMSGVEPEKLLTMAKMYAAPKTKVMSLWTMGVNQHTRGVWMQSLIYNLHLLTGKIAQPGNSPFSLTGQPSACGTAREVGTFAHRLPADMVVANPKHRAIAEKIWKLPEGTIPPKPGYHAVLQDRMLKDGKLNAYWVMCNNNMQAGPNINEERLPGYRNPDNFIVCSDPYPTVTAQAADLILPTAMWVEKEGAYGNAERRTQVWYQQVKAPAEAKSDLWQIMEFSKRFKVEEVWGDDLIAQMPEYRGKTMYDVLFKNGQVDKFPLTEAQELNDDAQAQGFYVQKGLFEEYASFGRGHGHDLAPYDTYHHVRGLRWPVVNGKETKWRFAEGSDPYVPEGSEFYFYGKPDGKANIIFAPFESAPETPDKEYDMWLCTGRVLEHWHTGTMTRRVPELYKAVPDAFCFIHPDDAKNRGLRRGDEVIVASRRGEINCRVETRGRNRPPVGLVFIPFFDARILVNKLILDATDPLSKQTDFKKCPVQIRKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZD7</accession>
    <name>D0YZD7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Xanthine-guanine phosphoribosyltransferase</fullName>
            <shortName evidence="3">XGPRT</shortName>
            <ecNumber evidence="3">2.4.2.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Xanthine phosphoribosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">gpt</name>
        <name evidence="5" type="ORF">VDA_002650</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi. To a lesser extent, also acts on hypoxanthine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>diphosphate + GMP = 5-phospho-alpha-D-ribose 1-diphosphate + guanine</text>
            <dbReference type="Rhea" id="RHEA:25424"/>
            <dbReference type="ChEBI" id="CHEBI:16235"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>diphosphate + IMP = 5-phospho-alpha-D-ribose 1-diphosphate + hypoxanthine</text>
            <dbReference type="Rhea" id="RHEA:17973"/>
            <dbReference type="ChEBI" id="CHEBI:17368"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>diphosphate + XMP = 5-phospho-alpha-D-ribose 1-diphosphate + xanthine</text>
            <dbReference type="Rhea" id="RHEA:10800"/>
            <dbReference type="ChEBI" id="CHEBI:17712"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="EC" id="2.4.2.22"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Purine metabolism; GMP biosynthesis via salvage pathway; GMP from guanine: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Purine metabolism; XMP biosynthesis via salvage pathway; XMP from xanthine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.22" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300602.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002650"/>
    <dbReference type="EnsemblBacteria" id="EEZ41618">
        <property type="protein sequence ID" value="EEZ41618"/>
        <property type="gene ID" value="VDA_002650"/>
    </dbReference>
    <dbReference type="GeneID" id="57341084"/>
    <dbReference type="eggNOG" id="COG2236">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1819460at2"/>
    <dbReference type="UniPathway" id="UPA00602">
        <property type="reaction ID" value="UER00658"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00909">
        <property type="reaction ID" value="UER00887"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052657">
        <property type="term" value="F:guanine phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004422">
        <property type="term" value="F:hypoxanthine phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000310">
        <property type="term" value="F:xanthine phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032263">
        <property type="term" value="P:GMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006166">
        <property type="term" value="P:purine ribonucleoside salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032265">
        <property type="term" value="P:XMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01903">
        <property type="entry name" value="XGPRT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023747">
        <property type="entry name" value="Xanthine_Guanine_PRibTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39563">
        <property type="entry name" value="PTHR39563"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0660">Purine salvage</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran" evidence="4">
        <location>
            <begin position="27"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="5-phospho-alpha-D-ribose 1-diphosphate binding" evidence="3">
        <location>
            <begin position="37"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="5-phospho-alpha-D-ribose 1-diphosphate binding" evidence="3">
        <location>
            <begin position="88"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="69"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="92"/>
            <end position="96"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="92"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="134"/>
            <end position="135"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="152" mass="17169" checksum="D060CAE18CA024CF" modified="2010-01-19" version="1">MTQKFVITWDNMQMYTRQLAEKLLPADQWKGIIAVSRGGLVPAAILARELGLRHVDTVCISSYDHDHQRDMRVLKQADGDGEGFIIIDDLVDTGGTAEKIREMYPRGKFVTVCAKPAGKHLVDDFVVDIPQDTWIEQPWDMAVTFVDPIAKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZF5</accession>
    <name>D0YZF5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative 4-methyl-5(B-hydroxyethyl)-thiazol monophosphate biosynthesis enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002668</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300656.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002668"/>
    <dbReference type="EnsemblBacteria" id="EEZ41636">
        <property type="protein sequence ID" value="EEZ41636"/>
        <property type="gene ID" value="VDA_002668"/>
    </dbReference>
    <dbReference type="GeneID" id="57341064"/>
    <dbReference type="eggNOG" id="COG0693">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1421548at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006287">
        <property type="entry name" value="DJ-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01383">
        <property type="entry name" value="not_thiJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DJ-1_PfpI" evidence="1">
        <location>
            <begin position="8"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="205" mass="21692" checksum="639D349A5F36F657" modified="2010-01-19" version="1">MTNSTPHVVVLIAPGTEEMEAVNSINILRRAGFTVTTASAAGDGALIVEGSRGIKLVADVPLIDIADQPFDCVVLPGGLGGSECFRDSDLVTAFVEQHHYDGKLIAAICAAPALVLVHHNMMPKAIMTCHPAFHDAIPAAQLRTKRVVYDKNHNLLTSQGPGTSQEFALEIIVQLAGKAKAADVAGPMVVWPNMHYDVLPSGHNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-02-10" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZG4</accession>
    <name>D0YZG4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transcription antitermination protein NusB</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Antitermination factor NusB</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">nusB</name>
        <name evidence="8" type="ORF">VDA_002677</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the NusB family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002677"/>
    <dbReference type="EnsemblBacteria" id="EEZ41645">
        <property type="protein sequence ID" value="EEZ41645"/>
        <property type="gene ID" value="VDA_002677"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0781">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription, termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031564">
        <property type="term" value="P:transcription antitermination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.940.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00073">
        <property type="entry name" value="NusB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035926">
        <property type="entry name" value="NusB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011605">
        <property type="entry name" value="NusB_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006027">
        <property type="entry name" value="NusB_RsmB_TIM44"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11078">
        <property type="entry name" value="PTHR11078"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01029">
        <property type="entry name" value="NusB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48013">
        <property type="entry name" value="SSF48013"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01951">
        <property type="entry name" value="nusB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 6" id="KW-0889">Transcription antitermination</keyword>
    <keyword evidence="4 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="NusB" evidence="7">
        <location>
            <begin position="7"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ41645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="152" mass="17438" checksum="5BDD9D4BCF00DA19" modified="2010-01-19" version="1">MKPAARRNARQFAVQAIYSWQITQGDIADIEQHFLSGDKFEEEEYQAEAPVLAAPHTDVNYFRDLFTGVVLNHQDLDSKMRPYLSRPLQDLDQMELALLRLAMYEMVKREDVPFKVVINEAIELAKLFGAEDSHKFVNGVLDKAAPSLRKDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZM7</accession>
    <name>D0YZM7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002740</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300875.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41708">
        <property type="protein sequence ID" value="EEZ41708"/>
        <property type="gene ID" value="VDA_002740"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG50311Q1">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1638474at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010424">
        <property type="entry name" value="EutQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06249">
        <property type="entry name" value="EutQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="130" mass="14163" checksum="5E130CA54ABFE799" modified="2010-01-19" version="1">MTTLTEKSGITLIKAGSFKLNDLSKLLEVEGLKSDMAEVAVTNNSAPLTIGHFTMSPGVEFEYFYDSVEYKVVTKGKIVMRDTDGNKYVAEVGDVILFSPDVTVIFDAESDGEAIYTAHRQAAEDFAPAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZT4</accession>
    <name>D0YZT4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative SpoOM-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002797</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301035.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41765">
        <property type="protein sequence ID" value="EEZ41765"/>
        <property type="gene ID" value="VDA_002797"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4326">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1033384at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009776">
        <property type="entry name" value="Spore_0_M"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40053">
        <property type="entry name" value="PTHR40053"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07070">
        <property type="entry name" value="Spo0M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="242" mass="26910" checksum="4CB790701BF01ED5" modified="2010-01-19" version="1">MFTKLKASLGIGGAKVDTIVDNSVLYQGETLRGTIHIHGGEVTQQVDAIHLKLNTEVQVETEQNSHYEVLTLGSLQLTDSFEIEAHQQLEIPFTLALHDETPITVLNASHNQSHVWIETTLDLNFAIDPQDRDYLEIKPLPVVEKILQTIENRGYTLAKADVEKGQLRGNGFLSQSGCYQEIEFRNDSMFSDKELELSFVLEGSLVHCLVEVDAGRGDHYFSFSLPLMATDNEIEGVLAGVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z015</accession>
    <name>D0Z015_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Probable endonuclease 4</fullName>
            <ecNumber evidence="7">3.1.21.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Endodeoxyribonuclease IV</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Endonuclease IV</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">nfo</name>
        <name evidence="9" type="ORF">VDA_002878</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>Endonucleolytic cleavage to 5'-phosphooligonucleotide end-products.</text>
            <dbReference type="EC" id="3.1.21.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 3 Zn(2+) ions.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the AP endonuclease 2 family.</text>
    </comment>
    <dbReference type="EC" id="3.1.21.2" evidence="7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301263.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002878"/>
    <dbReference type="EnsemblBacteria" id="EEZ41846">
        <property type="protein sequence ID" value="EEZ41846"/>
        <property type="gene ID" value="VDA_002878"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0648">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1088517at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008833">
        <property type="term" value="F:deoxyribonuclease IV (phage-T4-induced) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00019">
        <property type="entry name" value="AP2Ec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00152">
        <property type="entry name" value="Nfo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001719">
        <property type="entry name" value="AP_endonuc_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018246">
        <property type="entry name" value="AP_endonuc_F2_Zn_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21445">
        <property type="entry name" value="PTHR21445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00518">
        <property type="entry name" value="AP2Ec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00587">
        <property type="entry name" value="nfo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00729">
        <property type="entry name" value="AP_NUCLEASE_F2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00730">
        <property type="entry name" value="AP_NUCLEASE_F2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00731">
        <property type="entry name" value="AP_NUCLEASE_F2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51432">
        <property type="entry name" value="AP_NUCLEASE_F2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7 9" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4 7 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="AP_endonuc_2" evidence="8">
        <location>
            <begin position="21"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="145"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="216"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="229"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="261"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="280" mass="31249" checksum="2D90B81E4211DB79" modified="2010-01-19" version="1">MKLIGAHVSAAGGVYNAPLNAHNIGANAFALFTKNQRQWIAKPLEQSAITAFKARCQQYGFHPEAILPHDSYLINLGSPDAEKLEKSRNAFIDEMDRCQQLGLHLLNFHPGSHLKKISESDCLALIAESINMAHQAVPNVVAVIENTAGQGSNLGWRFEHLAEIIAQVEDKTRVGVCIDTCHTFAAGYDLRTEQATEQTFAEFDQIVGMHYLRGMHLNDSKGKLGSHLDRHNSLGVGEIGWDCFRYLMQDPRFDNIPLVLETIDPDIWQQEIAKLRSFCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z032</accession>
    <name>D0Z032_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative inner membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_002895</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0126 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301289.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002895"/>
    <dbReference type="EnsemblBacteria" id="EEZ41863">
        <property type="protein sequence ID" value="EEZ41863"/>
        <property type="gene ID" value="VDA_002895"/>
    </dbReference>
    <dbReference type="GeneID" id="57340813"/>
    <dbReference type="eggNOG" id="COG2860">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1665397at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005115">
        <property type="entry name" value="Gly_transporter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03458">
        <property type="entry name" value="Gly_transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="30"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="63"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="149"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="173"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="Gly_transporter" evidence="8">
        <location>
            <begin position="5"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="Gly_transporter" evidence="8">
        <location>
            <begin position="92"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="204" mass="21719" checksum="8782C6C11C01DF6C" modified="2010-01-19" version="1">MLIYILDMFGTAIFAISGVLLAGRLRMDPFGVVVLASVTAIGGGTIRDMALGATPVFWIHDTNYLWVIFITCIVSMWAVQQPKKMPWYFLPVADAIGLAVFVAIGVEKSLRFGASPMVAVIMGVITGCGGGVIRDVLAREVPMVLRTEVYATACILGGIIHTSALSLGVHADVAAFAGIITTLTIRLAAIRWHLSLPAFALRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z043</accession>
    <name>D0Z043_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">(GlcNAc)2 ABC transporter permease component 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_002906</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002906"/>
    <dbReference type="EnsemblBacteria" id="EEZ41874">
        <property type="protein sequence ID" value="EEZ41874"/>
        <property type="gene ID" value="VDA_002906"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0601">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="70"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="110"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="226"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="270"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="71"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="300" mass="33228" checksum="F7DAE319D0BDFD75" modified="2010-01-19" version="1">MPGDPVTMMFANATVQVTPERIEAMKKLLGFVDGPWYEQYWTYIQGVLTWNLGTSIKFYPQTVNDLLGGAIGWSLFLAGSAVILSFCIGSVLGIFAAWKRGSRYDSFISPGMLVIQAVPPVVVAMLVLFTFAIGLRWFPTGYAYTPGTLPDWTSWTFYQNVLYHAALPLFCATIIQIGGFLINMRNNMINLLSEDYITMAKGKGLSENRVVFNYAARNAMLPSVTALSMALGMAIGGQLIVEIIFNYPGLGTTLLNAIHGRDYQVLQGQLIIMTLFMLFFNFLADILIVILDPRLRKGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z050</accession>
    <name>D0Z050_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Chitobiose phosphorylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_002913</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002913"/>
    <dbReference type="EnsemblBacteria" id="EEZ41881">
        <property type="protein sequence ID" value="EEZ41881"/>
        <property type="gene ID" value="VDA_002913"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3459">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033432">
        <property type="entry name" value="GH36_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037018">
        <property type="entry name" value="Glyco_hydro_65_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010383">
        <property type="entry name" value="Glyco_hydrolase_94"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17167">
        <property type="entry name" value="Glyco_hydro_36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06165">
        <property type="entry name" value="Glyco_transf_36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="SSF74650"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_transf_36" evidence="2">
        <location>
            <begin position="4"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_36" evidence="3">
        <location>
            <begin position="128"/>
            <end position="559"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="633" mass="70477" checksum="A6E97FEB5B88EE6B" modified="2010-01-19" version="1">MSLYSAGTSYEDGVLLYDLYYNTSEKDGFYFLTSSFDPDSYDGQRDTFLGAYRDEANPIAVEKGRCSNHVQTCYNHCGSLHKQFTIEPGQEVRFNLVLGVGKHDARPLREKYQDFANVDAAFADIKQHWDTRCEKFQVKSPNEGLDTMINAWTLYQAETCVVWSRFASFIEVGGRTGLGYRDTAQDAISVPHANPAMTRKRLVDLLRGQVKAGYGLHLFDPDWFDPEKADVKPSKSPTVVPTPSDADKIHGIEDTCSDDHLWLVPTICRYVQETGEEAFLDQVIPYADGGNATVYEHMKAALDFSAEYVGQTGICKGLRADWNDCLNLGGGESAMVSFLHFWALQEFINLAKYQGKSEDVAKYTEMAANVREACETHLWDDEGGWYIRGLTKNGDKIGTAQQTEGRIHLESNTLAVLSGMASQERGEKAMDAVDENLFSEYGLHLNAPSFATPNDDIGFVTRVYQGVKENGAIFSHPNPWAWVAEAKLGRGDRAMKFYDALNPFNQNDIIEKRIAEPYSYVQFIMGRDHQDHGRANHPWLTGTSGWAYFAVTNFMLGVQTGFDGLTINPCIPTDWPGFEVTRQWRGATYNITVESPEHVSKGVKSITLNGEVISGAIPAQAEGSVNTVVVVMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z084</accession>
    <name>D0Z084_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">General secretion pathway protein A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002947</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002947"/>
    <dbReference type="EnsemblBacteria" id="EEZ41915">
        <property type="protein sequence ID" value="EEZ41915"/>
        <property type="gene ID" value="VDA_002947"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3409">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.101.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002477">
        <property type="entry name" value="Peptidoglycan-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036365">
        <property type="entry name" value="PGBD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036366">
        <property type="entry name" value="PGBDSf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13401">
        <property type="entry name" value="AAA_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01471">
        <property type="entry name" value="PG_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47090">
        <property type="entry name" value="SSF47090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="42"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="547" mass="61170" checksum="857DC6C6B1B989B8" modified="2010-01-19" version="1">MYKDFFGISEAPFSIVPSARFLFLSERHREALTHMLFGVTDGGGFGLLTGEVGTGKTTVLRAMIARLSQETQVAVILNPALSAHELLAAICDEFALSYTDSASLKQLSDLLHQHLLANHSEGKQTLLLVDEAQHLMPEVLEQLRLLTNLETDSRKLLKVVLIGQPELQQLLQQERLRQLAQRITSRYHLLPLTVEEVGEYIRYRLRSVGCHYDVFDDGVIRYIAKETQCIPRLINLICDKSMQLAHHQGVHQVTKAIAEQACEDVLSWQVPINRGQIESSKQTFNWSRWLLLSLLGGGLAAGAWLATEHLSLPLGVQTATTAAKVVTTDTQLGPMAKESAQELSSEQRLDTAIKASYQQRQAMQTLYQLWGFDSALNQATCATSSRVHLTCYSGKGSLTSLAMINRPVIVKLQDAHHHDFYAVLYAVTHNQVQLLLGHERIAVTPSWFEQRWDGNYQLLWRPPFGDDASIRYGQQGPRVAWLNQQLNTFLGEPQTNQNYFDQGLVDKLRRFQRSQSLNADGIAGKQTLMVLDSALSLPGPTLQPEGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0C7</accession>
    <name>D0Z0C7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Flavin prenyltransferase UbiX</fullName>
            <ecNumber evidence="5">2.5.1.129</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ubiX</name>
        <name evidence="7" type="ORF">VDA_002990</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>dimethylallyl phosphate + FMNH2 = phosphate + prenyl-FMNH2</text>
            <dbReference type="Rhea" id="RHEA:37743"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
            <dbReference type="ChEBI" id="CHEBI:87467"/>
            <dbReference type="ChEBI" id="CHEBI:88052"/>
            <dbReference type="EC" id="2.5.1.129"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the UbiX/PAD1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.129" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301494.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002990"/>
    <dbReference type="EnsemblBacteria" id="EEZ41958">
        <property type="protein sequence ID" value="EEZ41958"/>
        <property type="gene ID" value="VDA_002990"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0163">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1384786at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106141">
        <property type="term" value="F:flavin prenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1950">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01984">
        <property type="entry name" value="ubiX_pad"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036551">
        <property type="entry name" value="Flavin_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003382">
        <property type="entry name" value="Flavoprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004507">
        <property type="entry name" value="UbiX-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43374">
        <property type="entry name" value="PTHR43374"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02441">
        <property type="entry name" value="Flavoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52507">
        <property type="entry name" value="SSF52507"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00421">
        <property type="entry name" value="ubiX_pad"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 5" id="KW-0288">FMN</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="1 5" id="KW-0637">Prenyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Flavoprotein" evidence="6">
        <location>
            <begin position="4"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="12"/>
            <end position="14"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>dimethylallyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:88052"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>dimethylallyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:88052"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="206" mass="22601" checksum="23BD33EA4B2182EA" modified="2010-01-19" version="1">MRDKRITLAWTGASGAPYGLRLLQSLLAAEFEVYLLISSAARVVLATEHGLKLSANPEIAKSQLVEHLACEAHFLHVCGKDDWFSPVASGSAAPKQMVVCPCSAGCVAAIAHGMSDNLLERAADVVLKERGQLLLVVRETPFSTLHLENMLKLSQMGVTIMPAAPGFYHQPQSIEDLIDFMVARILDHLQIEQKLVPRWGYDNRQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0G4</accession>
    <name>D0Z0G4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Flavohemoprotein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Flavohemoglobin</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Hemoglobin-like protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Nitric oxide dioxygenase</fullName>
            <shortName evidence="13">NO oxygenase</shortName>
            <shortName evidence="13">NOD</shortName>
            <ecNumber evidence="13">1.14.12.17</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">hmp</name>
        <name evidence="18" type="ORF">VDA_003028</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 13">Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>NADH + 2 nitric oxide + 2 O2 = H(+) + NAD(+) + 2 nitrate</text>
            <dbReference type="Rhea" id="RHEA:19469"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16480"/>
            <dbReference type="ChEBI" id="CHEBI:17632"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.14.12.17"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 13">
            <text>NADPH + 2 nitric oxide + 2 O2 = H(+) + NADP(+) + 2 nitrate</text>
            <dbReference type="Rhea" id="RHEA:19465"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16480"/>
            <dbReference type="ChEBI" id="CHEBI:17632"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.14.12.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="13">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
        <text evidence="13">Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.</text>
    </comment>
    <comment type="domain">
        <text evidence="13">Consists of two distinct domains; an N-terminal heme-containing oxygen-binding domain and a C-terminal reductase domain with binding sites for FAD and NAD(P)H.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the globin family. Two-domain flavohemoproteins subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.14.12.17" evidence="13"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301634.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003028"/>
    <dbReference type="EnsemblBacteria" id="EEZ41995">
        <property type="protein sequence ID" value="EEZ41995"/>
        <property type="gene ID" value="VDA_003028"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1017">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1018">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1834577at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008941">
        <property type="term" value="F:nitric oxide dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019825">
        <property type="term" value="F:oxygen binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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    <dbReference type="GO" id="GO:0005344">
        <property type="term" value="F:oxygen carrier activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051409">
        <property type="term" value="P:response to nitrosative stress"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009636">
        <property type="term" value="P:response to toxic substance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01252">
        <property type="entry name" value="Hmp"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000971">
        <property type="entry name" value="Globin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009050">
        <property type="entry name" value="Globin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012292">
        <property type="entry name" value="Globin/Proto"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023950">
        <property type="entry name" value="Hmp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43396:SF3">
        <property type="entry name" value="PTHR43396:SF3"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00042">
        <property type="entry name" value="Globin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46458">
        <property type="entry name" value="SSF46458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01033">
        <property type="entry name" value="GLOBIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 13" id="KW-0216">Detoxification</keyword>
    <keyword evidence="13" id="KW-0274">FAD</keyword>
    <keyword evidence="13" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 13 15" id="KW-0349">Heme</keyword>
    <keyword evidence="10 13" id="KW-0408">Iron</keyword>
    <keyword evidence="7 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 13" id="KW-0520">NAD</keyword>
    <keyword evidence="8 13" id="KW-0521">NADP</keyword>
    <keyword evidence="9 13 18" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13 15" id="KW-0561">Oxygen transport</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13 15" id="KW-0813">Transport</keyword>
    <feature type="domain" description="GLOBIN" evidence="16">
        <location>
            <begin position="1"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="17">
        <location>
            <begin position="150"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Reductase" evidence="13">
        <location>
            <begin position="147"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="13">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="13">
        <location>
            <position position="135"/>
        </location>
    </feature>
    <feature type="binding site" description="proximal binding residue" evidence="13">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="204"/>
            <end position="207"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="268"/>
            <end position="273"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="388"/>
            <end position="391"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="site" description="Involved in heme-bound ligand stabilization and O-O bond activation" evidence="13">
        <location>
            <position position="29"/>
        </location>
    </feature>
    <feature type="site" description="Influences the redox potential of the prosthetic heme and FAD groups" evidence="13">
        <location>
            <position position="84"/>
        </location>
    </feature>
    <feature type="site" description="Influences the redox potential of the prosthetic heme and FAD groups" evidence="13">
        <location>
            <position position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS01033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EEZ41995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="395" mass="44550" checksum="19342D9CF37CB7F8" modified="2010-01-19" version="1">MISQQTIDIVKATTPVIAETGPALTAHFYQRMFQHNPELKDIFNLSHQRNGAQREALFNAICAYATNIENLEALLPAVEKIAHKHTSFMITAEQYQIVGHHLLATIDELLSPGQEVLDAWAEAYGVLANIFITREEDIYQENEAKQGGWRGTREFELVEKRQESDVITSFTFKPTDGQPVAAFKPGQYLGVYLKPEQFEFQEIRQYSLSSAPQPNTYRISVKREDGGLVSSYLHDSLVEGDKVLLAAPAGDFFLEENPTAPVTLISAGVGLTPTLAMLETLQQHDQSVYWLHAAHNGRHHAFKDHIKQLALKNAQIKPTTWYQEPQADDVLSEDYDYVGLIDLTQLAAELTKDKDMQFYFCGPVGFMQHVAKQLMAMGVEQDRLHYECFGPHKVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0L5</accession>
    <name>D0Z0L5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Maltose regulon regulatory protein MalI (Repressor for malXY)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_003079</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003079"/>
    <dbReference type="EnsemblBacteria" id="EEZ42046">
        <property type="protein sequence ID" value="EEZ42046"/>
        <property type="gene ID" value="VDA_003079"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001761">
        <property type="entry name" value="Peripla_BP/Lac1_sug-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00532">
        <property type="entry name" value="Peripla_BP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="14"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ42046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="348" mass="37865" checksum="58341614B14AC6A4" modified="2010-01-19" version="1">MTENKNEEMTIKKVKITDVAHHAGVSVSTVSLVLGNKGRISEATIAKVHQAIDELGYVCNKAAANLRSHQSNLIGLILRDITDPFYTEVTAGISQELEQHGLMLFLAQSNNDPEKLKQCVQSMVQQGVAGILFSPVRGVTSELLTMTKQAGVPTVCIAKASVSSEVDYIGPDNNFAAILATKHLIEQGHRHIAYVGGKSDSLTRAERIGGYCSTLMQYGLPFKPEWIIECNSSQKQAAENIERLLTQHPKITALLCHRPATAIGAIYGIKRAGKNIGRDQYIGQQVAILGFDDVPEAELTEPALSFIATSAKEIGHQAGKRLLARMKEPESPIQRLILPPQLIIRESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0T3</accession>
    <name>D0Z0T3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 13">DNA polymerase I</fullName>
            <ecNumber evidence="3 13">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">polA</name>
        <name evidence="17" type="ORF">VDA_003147</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 13">
            <text>a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Single-chain monomer with multiple functions.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 13">Belongs to the DNA polymerase type-A family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="3 13"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302001.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003147"/>
    <dbReference type="EnsemblBacteria" id="EEZ42114">
        <property type="protein sequence ID" value="EEZ42114"/>
        <property type="gene ID" value="VDA_003147"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0258">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0749">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1220182at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09898">
        <property type="entry name" value="H3TH_53EXO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002562">
        <property type="entry name" value="3'-5'_exonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020046">
        <property type="entry name" value="5-3_exonucl_a-hlix_arch_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002421">
        <property type="entry name" value="5-3_exonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036279">
        <property type="entry name" value="5-3_exonuclease_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019760">
        <property type="entry name" value="DNA-dir_DNA_pol_A_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001098">
        <property type="entry name" value="DNA-dir_DNA_pol_A_palm_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020045">
        <property type="entry name" value="DNA_polI_H3TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018320">
        <property type="entry name" value="DNA_polymerase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002298">
        <property type="entry name" value="DNA_polymerase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008918">
        <property type="entry name" value="HhH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10133">
        <property type="entry name" value="PTHR10133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01367">
        <property type="entry name" value="5_3_exonuc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02739">
        <property type="entry name" value="5_3_exonuc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00476">
        <property type="entry name" value="DNA_pol_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01612">
        <property type="entry name" value="DNA_pol_A_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00868">
        <property type="entry name" value="DNAPOLI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00474">
        <property type="entry name" value="35EXOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00475">
        <property type="entry name" value="53EXOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00279">
        <property type="entry name" value="HhH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00482">
        <property type="entry name" value="POLAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47807">
        <property type="entry name" value="SSF47807"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00593">
        <property type="entry name" value="pola"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00447">
        <property type="entry name" value="DNA_POLYMERASE_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0227">DNA damage</keyword>
    <keyword evidence="13" id="KW-0234">DNA repair</keyword>
    <keyword evidence="13" id="KW-0235">DNA replication</keyword>
    <keyword evidence="11 13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10 13" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="9" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6 13 17" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13 17" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="53EXOc" evidence="15">
        <location>
            <begin position="7"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="3'-5' exonuclease" evidence="14">
        <location>
            <begin position="324"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="domain" description="POLAc" evidence="16">
        <location>
            <begin position="680"/>
            <end position="887"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EEZ42114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="923" mass="102308" checksum="C662AFCAD23D554F" modified="2010-01-19" version="1">MATIPENPLILIDGSSYLYRAYHAAPNFTNSEGQPTGAVYGVINMLRSMLRQFSTEHIAVIFDAKGKTFRDEMFADYKANRPPMPDDLRGQIEPLHAVIKAMGLPLISISGVEADDVIGTLATQASKAGMPVLISTGDKDMAQLVDENITLINTMTDVVMDPAGVVEKFGIGPELIIDYLALMGDKVDNIPGVPGVGEKTAKALLTGIGGLDALYDRLDEIPALGFRGSKTMPKKLLDNKEGAYLSYQLATIKLDVELDITPQELVKAEPDVDELTRLFGQLQFRRWLEEMLSGSDGKIVADEKAAQAVASEKVIAPVIDRSGYEVILDQSRFDAWLEQLKSAEAFAFDTETDSLDYMVANLVGVSFAVEEGKAAYVPVAHDYLDAPEQLDRDWVLAQLKPLLEDPNQAKIGQNLKYDASVIARYGIEMQGIKYDTMLESYVYNSVVGRHDMDSLALRYLEHKNISFEEIAGKGKGQLTFNQIDLEQAGPYAAEDADITLRLHNALYPKVSADEKLLHVFSDIEMPLVPVLSRMERTGVLIDSMKLSAQSQEIAQRLDELEKRAFEIADQEFNLSSPKQLQAILFEKMGLPVLKKTPSGTPSTNEEVLQELALDYPLPKLILEYRGLAKLKSTYTDKLPKMVNPATGRVHTSYHQAVTATGRLSSSDPNLQNIPVRNDEGRRIRQAFIAPQGYKVLAIDYSQIELRIMAHLSGDKALLDAFCHGKDIHAATAAEILGLPLDQVSSEQRRRAKAINFGLIYGMSAFGLAKQLDMGRGEAQEYMNTYFERYPGVLEYMETTRTVASEQGYVETLFGRRLYLPDIKSRNGLRRKAAERAAINAPMQGTAADIIKRAMVLVDEWIGQQESGRVRLLMQVHDELVFEVQESEIESVAQEIKTLMESAAQLDVPLIADIGYGENWDQAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0X2</accession>
    <name>D0Z0X2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alcohol dehydrogenase</fullName>
            <ecNumber evidence="3">1.1.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_003186</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.1" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302105.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003186"/>
    <dbReference type="EnsemblBacteria" id="EEZ42153">
        <property type="protein sequence ID" value="EEZ42153"/>
        <property type="gene ID" value="VDA_003186"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1454">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1456634at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004022">
        <property type="term" value="F:alcohol dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001670">
        <property type="entry name" value="ADH_Fe/GldA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018211">
        <property type="entry name" value="ADH_Fe_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039697">
        <property type="entry name" value="Alcohol_dehydrogenase_Fe"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11496">
        <property type="entry name" value="PTHR11496"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00465">
        <property type="entry name" value="Fe-ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00913">
        <property type="entry name" value="ADH_IRON_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00060">
        <property type="entry name" value="ADH_IRON_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe-ADH" evidence="2">
        <location>
            <begin position="8"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ42153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="383" mass="40817" checksum="34286E0231CF8BFA" modified="2010-01-19" version="1">MSNVFYMPPVTLMGPNAIQSLGAELASKELKKALIVTDKVLVEVGLVNKLTEELASHQLDYVIYDGVQPNPTEKNIEDGLELLATSQCDFVISFGGGSSHDTAKGIALVAANGGHIRDYSKGVHLSKKPQLPLVTVNTTAGTASEMTVFAIITNQEDETKYPVVDKHFTPIIAVNDSELMVAMPKFLTAATGMDALTHAIEAYVSTAATPITDASAIKAIELIVNNLETAVNDGQNRAARDAMQYGEYLAGMAFSNASLGYVHSMAHQLGGVYDLAHGLCNAILLAEVSRFNAQQVPERFVDIAKAMGGDVSAMTQEQAVNAALEAIDALSEKVGTKQRLGDLGVTEDKLAFMAQNALNDACSLTNPRKASLEEIIAIFKARM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0Y0</accession>
    <name>D0Z0Y0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_003194</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302125.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003194"/>
    <dbReference type="EnsemblBacteria" id="EEZ42161">
        <property type="protein sequence ID" value="EEZ42161"/>
        <property type="gene ID" value="VDA_003194"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG50331AY">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1924250at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009962">
        <property type="entry name" value="DUF1488"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036692">
        <property type="entry name" value="Shew3726-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07369">
        <property type="entry name" value="DUF1488"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160272">
        <property type="entry name" value="SSF160272"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ42161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="88" mass="10149" checksum="98B08DBF22787B4F" modified="2010-01-19" version="1">MNQDILFADIQLWDSVRQAVNFPAQQAGALITCWVSLAWLQQHSPNLELANKEIILARFVELRFDLEEIAEEMIEDERFDECGDIIIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0Z5</accession>
    <name>D0Z0Z5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Hypothetical GntR-famly transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_003209</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302170.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003209"/>
    <dbReference type="EnsemblBacteria" id="EEZ42176">
        <property type="protein sequence ID" value="EEZ42176"/>
        <property type="gene ID" value="VDA_003209"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2186">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1045165at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011711">
        <property type="entry name" value="GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008920">
        <property type="entry name" value="TF_FadR/GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07729">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00035">
        <property type="entry name" value="HTHGNTR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00895">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48008">
        <property type="entry name" value="SSF48008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="4">
        <location>
            <begin position="11"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ42176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="224" mass="25677" checksum="341C9F98F645CEFF" modified="2010-01-19" version="1">MDQQQRIIANRNLSYKLAEAIGRRILEGETAPGDILPGEVELGEMYGVSRTAVREAIKMLAAKGLVLPRPRIGTRVMPKKNWNYLDQDLLAWLSFDKHSEIIAEFQKVRQTLEPQAAALAAINASDDERQELHQLMLEMHALGDDFNQDRWIEVDTRFHQLIYFASGNHFISPFGNLFKAVFEKYFRVVTREQILKLELHQQIVDGILEKDSDKAYQASLALVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z103</accession>
    <name>D0Z103_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Site-specific recombinase phage integrase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_003217</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302191.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003217"/>
    <dbReference type="EnsemblBacteria" id="EEZ42184">
        <property type="protein sequence ID" value="EEZ42184"/>
        <property type="gene ID" value="VDA_003217"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0582">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="238512at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0229">DNA integration</keyword>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyr recombinase" evidence="4">
        <location>
            <begin position="182"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="400"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ42184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="454" mass="52738" checksum="3525EB5E8049E98B" modified="2010-01-19" version="1">MAVRTLKSFQPWSHFGLDGKLAFRKPLDIPFVTYSNHTPCYEANAYIHSLIVRNLKSDTIRGYAHDIIHLVHFIEKQPLLSQFSQLTDATFTLFVQSLQAERTPLGELQRKNNSVIKIAHTCLDFLQFIQEFHDLSAFIGKDKSNSIQILEKHYKRKQEGYKGFIEGTKITHPAVPTKDEIKKRHPVSSDDALRVWEHIKTQENKDKRRRDMALYTAMEQLGGRVSELHLIKMTDYEEARRTGMLTLTTLKRKDDNTTRKIPVPHLLLSVIADYIKVRKKVMRKKKAQHDYLFVSLKTGLRLSADSWTTYMNSWKRELGIEGELHPHLWRHAFITDKLKELILATKEVNDKDDFRKHLLHTQTFKMQLQQWTGHRMLSSLDTYIDLAFADIHGYTEVYNAVSLKSSVDLAKRQIELLEEQIARKELTPTAALGEMKKLLEAFQSDIDKSIVSSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z111</accession>
    <name>D0Z111_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hypothetical transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003225</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ42192">
        <property type="protein sequence ID" value="EEZ42192"/>
        <property type="gene ID" value="VDA_003225"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1476">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="96" mass="11123" checksum="5A9B04967211EC77" modified="2010-01-19" version="1">MAKTLGIARQTYLDLESGKTEPRISTLVEIAQLTGRPLTWFVFDDEEKVMGDEHSEIQELLNLFGQVPSQVRSQLIKHNKEFISCWLDYITALKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z121</accession>
    <name>D0Z121_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">ATP synthase subunit c</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">ATP synthase F(0) sector subunit c</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">F-type ATPase subunit c</fullName>
            <shortName evidence="13">F-ATPase subunit c</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Lipid-binding protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">atpE</name>
        <name evidence="15" type="ORF">VDA_003235</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 13">F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.</text>
    </comment>
    <comment type="function">
        <text evidence="13">Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cell membrane</location>
            <topology evidence="13">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the ATPase C chain family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302247.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003235"/>
    <dbReference type="EnsemblBacteria" id="EEZ42202">
        <property type="protein sequence ID" value="EEZ42202"/>
        <property type="gene ID" value="VDA_003235"/>
    </dbReference>
    <dbReference type="GeneID" id="57340358"/>
    <dbReference type="eggNOG" id="ENOG5032S3K">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2078221at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045263">
        <property type="term" value="C:proton-transporting ATP synthase complex, coupling factor F(o)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01396">
        <property type="entry name" value="ATP_synth_c_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005953">
        <property type="entry name" value="ATP_synth_csu_bac/chlpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000454">
        <property type="entry name" value="ATP_synth_F0_csu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020537">
        <property type="entry name" value="ATP_synth_F0_csu_DDCD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038662">
        <property type="entry name" value="ATP_synth_F0_csu_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002379">
        <property type="entry name" value="ATPase_proteolipid_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035921">
        <property type="entry name" value="F/V-ATP_Csub_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00137">
        <property type="entry name" value="ATP-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00124">
        <property type="entry name" value="ATPASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81333">
        <property type="entry name" value="SSF81333"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01260">
        <property type="entry name" value="ATP_synt_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00605">
        <property type="entry name" value="ATPASE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 13" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="13" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 13" id="KW-0138">CF(0)</keyword>
    <keyword evidence="6 13" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 13" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 13" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 13" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="6"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="52"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-synt_C" evidence="14">
        <location>
            <begin position="10"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="site" description="Reversibly protonated during proton transport" evidence="13">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEZ42202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="85" mass="8691" checksum="0FEC0D188E01CFFE" modified="2010-01-19" version="1">METLLSFSAIAVGIIVGLAALGTAIGFALLGGKFLEGAARQPEMAPMLQVKMFIIAGLLDAVPMIGIVIALLFTFANPFVGQLAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1A2</accession>
    <name>D0Z1A2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">O-methyltransferase-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_003316</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302478.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003316"/>
    <dbReference type="EnsemblBacteria" id="EEZ42283">
        <property type="protein sequence ID" value="EEZ42283"/>
        <property type="gene ID" value="VDA_003316"/>
    </dbReference>
    <dbReference type="GeneID" id="57340243"/>
    <dbReference type="eggNOG" id="COG3315">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="847145at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007213">
        <property type="entry name" value="Ppm1/Ppm2/Tcmp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016874">
        <property type="entry name" value="TcmP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04072">
        <property type="entry name" value="LCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028177">
        <property type="entry name" value="Polyketide_synth_Omtfrase_TcmP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ42283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="265" mass="30490" checksum="B1C9F815F7EFEC7A" modified="2010-01-19" version="1">MVKSTRYKIPADLLQPLWLRSLESLADDGLIYDPVAAQACRQCQLVPDCVNQHIPARQLLHATLTAQCDRLVQDFLRRHPSGLVVNVGAGLDTRFYRLDNGRCRWFELDTDENLLWREKLFHRSERYTLQQGSVVELSWLKALPLKQGTPTLLLCDQALLQCSEQQVAQFIQHVACRLGHIEACLVVAGDQTTTNVAQKLGTVTYQHGLREPAQQVINWLPWAELLGCYSPLDYGCARWRYWQRWVAKCTQLKYRLTPVLIHLRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1B8</accession>
    <name>D0Z1B8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative xanthine/uracil permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_003332</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302508.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003332"/>
    <dbReference type="EnsemblBacteria" id="EEZ42299">
        <property type="protein sequence ID" value="EEZ42299"/>
        <property type="gene ID" value="VDA_003332"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2233">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1419334at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015205">
        <property type="term" value="F:nucleobase transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006043">
        <property type="entry name" value="NCS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017588">
        <property type="entry name" value="UacT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006042">
        <property type="entry name" value="Xan_ur_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00860">
        <property type="entry name" value="Xan_ur_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00801">
        <property type="entry name" value="ncs2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03173">
        <property type="entry name" value="pbuX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01116">
        <property type="entry name" value="XANTH_URACIL_PERMASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="57"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="119"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="146"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="182"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="208"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="248"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="338"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="366"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="396"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="426"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ42299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="468" mass="49139" checksum="554166DD4428A442" modified="2010-01-19" version="1">MSSQPKRNSDLIYGLNDRPPFAQSLFAATQHLLAMFVAVITPSLIICQSLGLPASDTNTIVSMSLFASGIASFIQIRTFGPVGSGLLSIQGTSFNFLGPIIGAGLALKAGGADIPTMMAAIFGTILFASLTEVVISRILQHAQRVITPLVSGIVVTLIGLTLIQIGLTSIGGGYSAIESGTFGSLNNLLLAGTVLGFIVLLNRVRNPYLRVSSIVIAMAMGTLLAWFMGMVDSSKMAQTDLIAIPMPMQYGLGFDWGLLIPLMIVFAITSLEAIGDITATSETSEQPVAGPVYLKRIKGGVLADGINSALAAALNSFPNSTFSQNNGIIQLTGVASRYIGYFVSAMLVLLGLFPGVANLVQLIPEPVLGGATIVMFGTIAASGVRIISRCHLDRRAILIMALSFSMGLGIAQKPEILQFMPDIVKSILSSGMAAGGITAILLNLILPEEHTQTQAETEQELEQQVAPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1N8</accession>
    <name>D0Z1N8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">30S ribosomal protein S14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rpsN</name>
        <name evidence="7" type="ORF">VDA_003452</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the universal ribosomal protein uS14 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302811.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003452"/>
    <dbReference type="EnsemblBacteria" id="EEZ42419">
        <property type="protein sequence ID" value="EEZ42419"/>
        <property type="gene ID" value="VDA_003452"/>
    </dbReference>
    <dbReference type="GeneID" id="57340091"/>
    <dbReference type="eggNOG" id="COG0199">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2032609at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00537">
        <property type="entry name" value="Ribosomal_S14_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001209">
        <property type="entry name" value="Ribosomal_S14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023036">
        <property type="entry name" value="Ribosomal_S14_bac/plastid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018271">
        <property type="entry name" value="Ribosomal_S14_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19836">
        <property type="entry name" value="PTHR19836"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00253">
        <property type="entry name" value="Ribosomal_S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00527">
        <property type="entry name" value="RIBOSOMAL_S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ42419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="101" mass="11510" checksum="8480248917BA13AB" modified="2010-01-19" version="1">MAKESMKAREAKRAKLVAKYAEKRAALKALISNVNASEEDRWNAVLKLQSLPRDSAKSRQRNRCNQTGRPHGYLRKFGLSRIKVREACMKGEIPGLRKASW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1R7</accession>
    <name>D0Z1R7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Aspartokinase</fullName>
            <ecNumber evidence="10">2.7.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">VDA_003481</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>ATP + L-aspartate = 4-phospho-L-aspartate + ADP</text>
            <dbReference type="Rhea" id="RHEA:23776"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57535"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 1/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="11">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 1/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="11">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 1/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the aspartokinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.4" evidence="10"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303568.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003481"/>
    <dbReference type="EnsemblBacteria" id="EEZ42448">
        <property type="protein sequence ID" value="EEZ42448"/>
        <property type="gene ID" value="VDA_003481"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0527">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1067792at2"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00015"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00461"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00462"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004072">
        <property type="term" value="F:aspartate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005260">
        <property type="entry name" value="Asp_kin_monofn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001341">
        <property type="entry name" value="Asp_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042199">
        <property type="entry name" value="AsparK_Bifunc_asparK/hSer_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018042">
        <property type="entry name" value="Aspartate_kinase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000726">
        <property type="entry name" value="Asp_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00656">
        <property type="entry name" value="asp_kin_monofn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00657">
        <property type="entry name" value="asp_kinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00324">
        <property type="entry name" value="ASPARTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 10 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACT" evidence="12">
        <location>
            <begin position="324"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="232"/>
            <end position="233"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="243"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000726-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ42448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="459" mass="49549" checksum="9BA06FEA8A03A78E" modified="2010-01-19" version="1">MSLEHNGTASHPSLTVAKFGGTSVADHHAMQLSALVVKNNPATKVVLISACSGVTNILVELAAGISDLPLREQRLEQLRTIHHNIAQQLQSPQLVEPQLEQLLAQVTQLSQQAATHPTLALTDELVAHGELLSTYLFTQVLNELDAPSIRRDIRPIMRTDDQFGRATPDIAVLRQQTQQHLIPLLEQGIVVSQGFIGSNEAGQTTTLGRGGSDYSAALIAEALDAETLEIWTDVPGIYTTDPRITAAAKPIQEISFTEAAEMATFGAKILHPSTLLPAIRQQIPVFIGSSKQPELGGTWIRQHVSEAPLFRALALRCNQTMVTLTSLNMFQAYGFLAEVFRILAAHKISVDLITTSEVSVSLTLDKTDTSGGAPTLPEAAIAELNQLCRVDIEQGLCLAALIGNGMSESKGAAKQVFGALADFNLRMICYGASAHNLCFLVQEQDAKEIIKVLHQQVIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1U4</accession>
    <name>D0Z1U4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Possible exported protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_003508</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303642.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003508"/>
    <dbReference type="EnsemblBacteria" id="EEZ42475">
        <property type="protein sequence ID" value="EEZ42475"/>
        <property type="gene ID" value="VDA_003508"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3164">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="29456at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032712">
        <property type="entry name" value="AsmA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011836">
        <property type="entry name" value="CHP02099"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025263">
        <property type="entry name" value="DUF3971"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38690">
        <property type="entry name" value="PTHR38690"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13502">
        <property type="entry name" value="AsmA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13116">
        <property type="entry name" value="DUF3971"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02099">
        <property type="entry name" value="TIGR02099"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3971" evidence="2">
        <location>
            <begin position="510"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="domain" description="AsmA_2" evidence="3">
        <location>
            <begin position="1035"/>
            <end position="1275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ42475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="1294" mass="143021" checksum="0D80A4E11742FE6A" modified="2010-01-19" version="1">MTSIPTKLARALLWLIVGGAVFSAITITGLRVTLPYIDRYQPQLTAWAEQQIGLPISVGTVNGRWFNAGPEFTLSNVALYREDSTQQIVSIGQVSVALNFWQSLLQAKPVFKDIEINQLKVDLTQLPKQKKTQEKQTKSWAEKLEQLFLVRLDRFTLQHSQITLYTPSGKSQQLDISDLNWRNNAGHHLAEGTVSVANSHLSRLKVMADFSEQGDLSSITGQFYVQASKLAVTPWLHQTFANIADIKNSEVSFESWINVKQGLIEQSTLALGPIDIAWQQNQVSHQFKLKRGVVSLAPLNSEPSSNQWYISTNDFAVTTDGQSWPQLNLQANVNLNRQYQLQDWKLQIADLNLARLRPLLGLFPQELPAIKTVTAMKPQGLISQLRVSDKQGQQPQFSADFSHVAIKQWQLIPGIHKLNGQVSGSLQQGKVQLSLTDDQLPYQGIFQAPLNIKQANVTGYWQVDKDGSWRLWSDHLAVTTPDLAANGVFRLDFPYQQPAWLSFYGDVDVKNAGATWRYLPIPALGTELTDYLSRAIRGGEAKGAKLLWYGALQDFPYSHHNGIFQVDVPLKKARFIFDTAWPELTDLQLDLVFKNDWMYLDSHHVKTMGAVGHRVTGASKLASDGHLKLDIDVAADGSAVRDYMLATPLVDSVGAALTTVQVSGPVSSQFSLDIPYDGSQVGVTGYALLNKNRVALQTPNIELDNVSGKLNFHDDKILAQGFSGRLLQQPIDLSFSGANQDEGYQVLVDLAGDWQLSPLQKQWQDPLLEQVSGSSQWQSHVAVHLNDTGFGYDVDLKAGLANIISKLPYPLAYIAAPKQQQYVTVKAQGDKEKVDVTAQLPDMNYQMRLNLQTNKPHIVASYAAIGKKQLLPWPLLGQRIDINSEQVNLDDWLDVLSSINHSFALAKQQGEPRTVPSIPLPTQINGQVKQLIVGQMPWHDVTLTARRNGANWHGNLASREATGTGNWHAPNQLNINLKRLFLTIPGLDKSHKLFREPYKITAQPFHVSAQDRAVMSAMPNINLSIADAWLQGYRLGKVEGQLLKKGSSLTLPKFSVTTGAMALNMQGAWQIKGNTSTTQLSAKIKGEDSTDLMGRLGISGGIQDASFKTNLSASWQGTPWQIRRETLTGQVKTKTGKGIISGVGGAGRLLGLFSIDSIIRKMQLDFSGIFENGLAFDYIKGSGDIKNGIFITKDLTMKALAGDMTIKGQANLVKETVDANVKFIPDFTSGIPVLTAFAVAPQTALYVFAISTALSPVLDVFTQVNYYVHGKIDDPVVTERSRFQGEYKLPETKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1W4</accession>
    <name>D0Z1W4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Outer membrane stress sensor protease DegS</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_003528</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S1C family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303703.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003528"/>
    <dbReference type="MEROPS" id="S01.275"/>
    <dbReference type="EnsemblBacteria" id="EEZ42495">
        <property type="protein sequence ID" value="EEZ42495"/>
        <property type="gene ID" value="VDA_003528"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0265">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="741829at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011783">
        <property type="entry name" value="Pept_S1C_DegS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001940">
        <property type="entry name" value="Peptidase_S1C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13180">
        <property type="entry name" value="PDZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00834">
        <property type="entry name" value="PROTEASES2C"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02038">
        <property type="entry name" value="protease_degS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDZ" evidence="4">
        <location>
            <begin position="247"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="352"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="2">
        <location>
            <position position="98"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="2">
        <location>
            <position position="128"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="2">
        <location>
            <position position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR611783-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ42495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="371" mass="39630" checksum="082ADBCD334D970F" modified="2010-01-19" version="1">MLAFLGRSVLLGLATAAILLLAVPDLRQNIISAPTVSISDDDSSSQLSFNYAVRRASPAVVNIYNRRYNTEDRLKLTTQGLGSGVIMSDKGYILTNYHVVAQADQVIVALQDGRFFTAQLIGKDQETDLAVLKINAENLPVIPVNPNYKAAVGDVVLAIGNPYNLGQTTTFGIISATGRSGVSFYGHQDFLQTDAAINEGNSGGALVNTKGELVGINTASFHPANIETYGISFAIPYESAIKIMKKLIADGRVIRGYIGIDGSEINPVMARLYDADQINGILVLGMNPDGPAAKAGIHVRDILVEIDGKPVKDMLSVLDIVTDIRPGTHVKVKVLRNGKPMILDVLIGNKPENLGTKPEPPVQQLPPVPPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z224</accession>
    <name>D0Z224_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Membrane protein functionally coupled to the MukBEF chromosome partitioning mechanism</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001873</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298852.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001873"/>
    <dbReference type="EnsemblBacteria" id="EEZ40841">
        <property type="protein sequence ID" value="EEZ40841"/>
        <property type="gene ID" value="VDA_001873"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1434">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1879123at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06259">
        <property type="entry name" value="YdcF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003848">
        <property type="entry name" value="DUF218"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02698">
        <property type="entry name" value="DUF218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="DUF218" evidence="2">
        <location>
            <begin position="81"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="278" mass="30983" checksum="0B3CB623E401A894" modified="2010-01-19" version="1">MFELKKLLSTLLMPLPALLIIGFIGLYLLWFTRRKGLAGGFITASLLGILLLSFQPISTSLLRPLEKQNAPFIPHSTPVNYVMVLGAGHVIDNAFPITSQLSRAALMRLVEGIRIYRMYPGSKLILSGYGGGSDISHARMMAKVALALDVNKADILLLETAKDTWEEAFQAASVVGDKNLVLVTSASHMSRALYEFHQAGLNPIPAPTNFLASNKIEQPWVRYAPSSKYLEQSERYWHERMGQIWQRLRDALVQEHVEKPQSAVSDVHDLEQDSKTAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z289</accession>
    <name>D0Z289_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000540</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304671.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39520">
        <property type="protein sequence ID" value="EEZ39520"/>
        <property type="gene ID" value="VDA_000540"/>
    </dbReference>
    <dbReference type="GeneID" id="57342825"/>
    <dbReference type="eggNOG" id="ENOG5033XDC">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1711942at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="143" mass="16738" checksum="5F84D0217F9407E1" modified="2010-01-19" version="1">MTQLSLEAIRQQLTERHFHADKVKIVTVEAMDPADLESCTTVENETFYNSYMNVIYGKGDRYVLGYRCNEAEIIDQAIIRKGDKYYDPTLQANSDNFEPYQFALLTEFQVFDMMKNAKSNKDFPPDVDFLFARAKYYKNIINK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z296</accession>
    <name>D0Z296_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000547</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304687.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000547"/>
    <dbReference type="EnsemblBacteria" id="EEZ39527">
        <property type="protein sequence ID" value="EEZ39527"/>
        <property type="gene ID" value="VDA_000547"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1802293at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="12"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="304" mass="35051" checksum="7F769B4D3B1B45F3" modified="2010-01-19" version="1">MESNYLQPLIKYDQNLMVALYVLLREKHISNAAKHLCISQSAVSQKLSKLRYIFNDNLLVRINNEMVLTPFALTLYPMLEAHISSAIDIFHMRHKTNDTMKKVYRICIIDGIGMDLVSKKSLDILKDMNFAVSFEIINRYDACVEDLNNGNLDLLIGSFDGLSNNIHQVNIGEMEYGLFADKNNPLLQRKSGKVTFDELYSEKFIDFKFHGKLGIEVKSVFNKNGKFLNTILSYSQYDLVAKALIDTEFLAFIPVGLVNTEELSKIELDMTLPKGKCYMYWHSVMEKDLFHKYLRNSFVNMSCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2D2</accession>
    <name>D0Z2D2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000583</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304772.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000583"/>
    <dbReference type="EnsemblBacteria" id="EEZ39563">
        <property type="protein sequence ID" value="EEZ39563"/>
        <property type="gene ID" value="VDA_000583"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502ZEUJ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1534908at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="228" mass="26393" checksum="D9F42C14AB6FF2EA" modified="2010-01-19" version="1">MEKLDLDEAQQIDRLYATPPVYEWELIVNPDSSRTKRSFGIFFLTVFVSILFYLTDSGWLSLLPIAVGSFMSPWCRYLFDADKRYYFAINQYGMYSRNEQIIPEIAYTIVRYSAWVGCGICLFAAILVGPIAFVGAGGAALLSFQMTNFRSVSYKNQCLFDGYVKLENYRENDYLLITENSMIPLIIPECRLPRIIEVIKQYNDSFDEEFVDLYKGCKSHIIILEIVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2I1</accession>
    <name>D0Z2I1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">YceI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000632</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304923.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39612">
        <property type="protein sequence ID" value="EEZ39612"/>
        <property type="gene ID" value="VDA_000632"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2353">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1767227at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007372">
        <property type="entry name" value="Lipid/polyisoprenoid-bd_YceI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036761">
        <property type="entry name" value="TTHA0802/YceI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04264">
        <property type="entry name" value="YceI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00867">
        <property type="entry name" value="YceI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101874">
        <property type="entry name" value="SSF101874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018842" description="YceI domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="YceI" evidence="2">
        <location>
            <begin position="21"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="186" mass="20372" checksum="3F4E838F1BCB4A4D" modified="2010-01-19" version="1">MKKTMGMLIAAMMSFSANSSDYVIDTKGAHASINFKISHLGYSFIKGRFNDFSGQFSYDPTNISASNVEVIVNTQSLDSNHAERDKHVRSDDFIDASKYPQAKFVSTKVVDKGDGNLEIFGDLTFHGQSKPIIIAAELIGAGKDPWGGERIGFIGATRLELAEFKIPVMGDSSYVDLELHVEGIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2K3</accession>
    <name>D0Z2K3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Error-prone repair protein UmuD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000654</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000654"/>
    <dbReference type="MEROPS" id="S24.003"/>
    <dbReference type="EnsemblBacteria" id="EEZ39634">
        <property type="protein sequence ID" value="EEZ39634"/>
        <property type="gene ID" value="VDA_000654"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1974">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06529">
        <property type="entry name" value="S24_LexA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039418">
        <property type="entry name" value="LexA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015927">
        <property type="entry name" value="Peptidase_S24_S26A/B/C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00717">
        <property type="entry name" value="Peptidase_S24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="SSF51306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_S24" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="79" mass="9135" checksum="9ED7320BA98A9035" modified="2010-01-19" version="1">MVGAGIYDGDLLVVDRAEEIKPGRIVIARIYDEFTCKRLVRYDESWWLQPENPTLQAFPMPEDSEIFGVVTRNIHNLLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2K8</accession>
    <name>D0Z2K8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000659</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304978.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000659"/>
    <dbReference type="EnsemblBacteria" id="EEZ39639">
        <property type="protein sequence ID" value="EEZ39639"/>
        <property type="gene ID" value="VDA_000659"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1119700at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="63"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="309" mass="34634" checksum="86E57EDB389F140E" modified="2010-01-19" version="1">MKNLLKSVILCGSLLTSLSGCEIVKWKGQYDTHSLKKQGFSEHSLLLKEGGTLNYWQGGQGEPLLLLHGFGGSASATWLATMQELSKHYYVIAPDLLWFGKSHSLGRSNLTTQTEAIWQLLDHLKVQRVNVAGISYGGFVTYSLMARPERINKAIIIASPGPIFSDEHLAQLCQRANVKNPEELFVPQDKSGIKKLYDQVFIKSPYIPDFIAEQIYDGYFKDWQPERESLLNTLTADRERLGKISTETLPKTLLIWGDKDQIFPLENGIALSHYLQAPIVVFPETAHGVTNEKPELTAKTIESFLSQVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2L5</accession>
    <name>D0Z2L5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000666</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304997.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000666"/>
    <dbReference type="EnsemblBacteria" id="EEZ39646">
        <property type="protein sequence ID" value="EEZ39646"/>
        <property type="gene ID" value="VDA_000666"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031D5W">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1884032at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021230">
        <property type="entry name" value="DUF2810"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10928">
        <property type="entry name" value="DUF2810"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="7"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="118" mass="13446" checksum="39649DBD789F2B76" modified="2010-01-19" version="1">MNLNQELQSLNNRMDKCQRKLAAAISRNDDVIIKQFRDEIEKLRKKIQNVKHRRSAKVTTQSKDAKSLSFHRALTKQEQADMGKLKKSVKGLVVVHPMTALGRSMGLKEVTGYAPQPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2X8</accession>
    <name>D0Z2X8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NlpC/P60 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000779</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C40 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305328.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000779"/>
    <dbReference type="EnsemblBacteria" id="EEZ39759">
        <property type="protein sequence ID" value="EEZ39759"/>
        <property type="gene ID" value="VDA_000779"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0791">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="682655at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000064">
        <property type="entry name" value="NLP_P60_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025606">
        <property type="entry name" value="NLPC/P60_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027017">
        <property type="entry name" value="P60_peptidase_YkfC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039439">
        <property type="entry name" value="SH3b1_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12912">
        <property type="entry name" value="N_NLPC_P60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00877">
        <property type="entry name" value="NLPC_P60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12913">
        <property type="entry name" value="SH3_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019015">
        <property type="entry name" value="P60_peptidase_YkfC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51935">
        <property type="entry name" value="NLPC_P60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019355" description="NlpC/P60 domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="domain" description="NlpC/P60" evidence="3">
        <location>
            <begin position="295"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="499" mass="57220" checksum="7CD7B9808748B71C" modified="2010-01-19" version="1">MNINKHLMLLALLTNYSYANGNNITIPIEITQDAFHYISHKDLDKNIIDKYTIRQMNEYFNTQYYFQWSDDANQNDFYYVPNNTQTKNNILKLENDTIRYYKERSGYDKNYLPHTSNWVNFISENMNLKSFPNIPCDNHSCRGIVVNNAQVRSLPTSDAFYNNFTIPGEGYPFDYIQLSALWTGTPIMLIHMSTDKKWTLIKGQGTLGWVPTSSIANVDESFITQWKRYRLVTPTVRKQDLPIEKYDINNKILEAGSILPGHKGKLKIPVKDKNGTATLLTVNSKNLKFTTWPMTPSYKNFAHQINNYIGMPYGWGGMDFNNDCSGLLKRLFSTFGIWLPRSSFYQANYAGQIYSMYGQSEEQRKELLVEQEGAIQLIPFMTLVSFGNSKTSTSHIGLYMGTTEYNHNKVAVMFNAPWGVKLVNGNNEQGRALVGQTLITPIGIGDAFTEGLSNQDWALQSLWNTVGFNTTLLTETPKNKRLYQGIDNSYSIEKYLFEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z336</accession>
    <name>D0Z336_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000837</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305488.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000837"/>
    <dbReference type="EnsemblBacteria" id="EEZ39817">
        <property type="protein sequence ID" value="EEZ39817"/>
        <property type="gene ID" value="VDA_000837"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2014">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1905652at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007161">
        <property type="entry name" value="DUF364"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025251">
        <property type="entry name" value="DUF4213"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04016">
        <property type="entry name" value="DUF364"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13938">
        <property type="entry name" value="DUF4213"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4213" evidence="2">
        <location>
            <begin position="98"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="DUF364" evidence="1">
        <location>
            <begin position="201"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="341" mass="37053" checksum="E50E33AD3B9AE95A" modified="2010-01-19" version="1">MQISQNSLTFCQDHYTLYVDTSSSEKTICFTSAIKQLQQTGWELSSQDDLFTINTTPLGYPVTILTCSSLEFAINHHGITPDPFAIIQAIGGGQLEQALAASIPNSIVVDSVLFGFNWVFVKAGNLCGIARSPERGTEGARTIRPKEGFAGKTLAQLAQYFCSFDPLCRALGLAAINAYWNRIDNPYHFNHTGGFSAITPPGNGLVIIGGFRSVQQRLPSAKIIEREPRPGDIAVEDAPMAFQTAQQLAITAQTLMNGSLEPILCSSRNVPHHLLVGPSAPLCPILFDYGIDEISGLIVKNPTKVMQFIAESGAMIMLDDLVESRYLCAKTYTEKPNPPVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z344</accession>
    <name>D0Z344_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000845</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305510.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000845"/>
    <dbReference type="EnsemblBacteria" id="EEZ39825">
        <property type="protein sequence ID" value="EEZ39825"/>
        <property type="gene ID" value="VDA_000845"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502ZBF9">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="212037at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="470" mass="54384" checksum="89BAFB773371813A" modified="2010-01-19" version="1">MSDQRLLTIPTFSIMLEHHTIMRDVIRTMDESGEPYVREASFISKLHRYIQGQSKDKQKQLRTAFSSDNLLATHILVDKDEFGGESRLIFDRAVIGVFRLFDRSLFQDLTDVALKIQLGGIRLLLEKLQSGTMLFSNSDLDFKELIDELFRQLSELLNSIRLNLVKMQTINQELSDASELAAKSHNPQVFSALQQESIEKISLLLSRHILPTRQFLDEKSRLKDGPNLFECLQSLRSQFDQHQDYQRANAMLRYEVSFNSFHKQISKVSQSVDQFLARSKKRLQQFNAIEGAFSELVNALDATKQNLKRSQIDGQFARDNGTFMGLMQQARPKVLRISSSEAYLNNVVSDIEARVVDRSLLEHSCYVDLVSVKDNSTEQRLARAEQIFELVKNMKMAEYQDLTLSLHRRLKDSFSDYHFVDLLEGLSFILRSEAMLDGHAVKMTNFRQRLAHGDNIYLYRKIRTERVTQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3J2</accession>
    <name>D0Z3J2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000993</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39973">
        <property type="protein sequence ID" value="EEZ39973"/>
        <property type="gene ID" value="VDA_000993"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG50341HF">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="131"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="185" mass="20725" checksum="3B78F5CC3FCC6514" modified="2010-01-19" version="1">MLDIIREVLGWTSVAFYISLTIFNSMKFTRYAAFASATNDTAWSILMGWWPKVILNLSVGAINAYRYVKDFTNTSKAIINTVAALMAGGILYVAYVAISSFINNPTISEALQFGDLALILLALYMTELKKYRILMFLSGFVGMAAYYGNPQMMIIKALVIGIMAYKLYSTRNQTEEEVKQQEANV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3R5</accession>
    <name>D0Z3R5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Hyaluronate lyase</fullName>
            <ecNumber evidence="7">4.2.2.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_001066</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the polysaccharide lyase 8 family.</text>
    </comment>
    <dbReference type="EC" id="4.2.2.1" evidence="7"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306131.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001066"/>
    <dbReference type="EnsemblBacteria" id="EEZ40046">
        <property type="protein sequence ID" value="EEZ40046"/>
        <property type="gene ID" value="VDA_001066"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5492">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="941406at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030340">
        <property type="term" value="F:hyaluronate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008929">
        <property type="entry name" value="Chondroitin_lyas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038970">
        <property type="entry name" value="Lyase_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011071">
        <property type="entry name" value="Lyase_8-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012970">
        <property type="entry name" value="Lyase_8_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004103">
        <property type="entry name" value="Lyase_8_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003159">
        <property type="entry name" value="Lyase_8_central_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38481">
        <property type="entry name" value="PTHR38481"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02278">
        <property type="entry name" value="Lyase_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02884">
        <property type="entry name" value="Lyase_8_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08124">
        <property type="entry name" value="Lyase_8_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48230">
        <property type="entry name" value="SSF48230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49863">
        <property type="entry name" value="SSF49863"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="SSF74650"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019385" evidence="3">
        <location>
            <begin position="23"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="domain" description="Lyase_8_N" evidence="6">
        <location>
            <begin position="50"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="Lyase_8" evidence="4">
        <location>
            <begin position="429"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="domain" description="Lyase_8_C" evidence="5">
        <location>
            <begin position="697"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="214"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="806" mass="90980" checksum="F95C2DEDFD71AC47" modified="2010-01-19" version="1">MKQLSLLTLSIICAFSSIPVQANDNESANIALTSQLEVNEQAFSQLRQKWAEGFLGASDIAFDQKLKQMVITANNGAQKHWSSMNTASTRLSLWNDLVLDDQSEAGKKVLGAKLRSSYQRLFIMAKAYQLRGGVLQHNPQLLAAIIDGLQFLNQHYYKVGAKEWGNWWHWELGTPKDIHNILVVLYDQLPAQLITNYLDATRYFTPLPTHLGAGSGADVSSNPHYRESTGGNRTDNTQVVLLRGILANDSDEIFSAIQALSPVVDYVQASDGFYQDGSFLQHYDIAYNGTYGNVLLGGLGAQMSLVANSPWQVTDPKLQEIYPLIFKSYAPLLYRGTMMEFVNGRAISRPQEQGHHVGHNVIASLIHYLDGASAQYLYPLQQLIKTQISQDTYLDFFDSINHIGNYQKAQQLLQNPQIDVKDNVQGVFTFPAMDRVVYRTDDWAFSLAMHSSRLGNFECMNNENRKGWFTGDGMSYFYTNQLDHFHDYWPVVDSYRLPGTTVDDQLMLECQGQRNQIKGGRKLQMDWVGSAKLDDIAVAGMDFINWNETLTAKKSWFMFDDEVVMLGSNISSQIGANITTTVANRKQLDNGNINVFINEYPWAGQYPNKIKSLFISNDQMDESGMGYIFLSPPELSVKQDTRIGNWNEIGTKSGEVSAEFITATIRHSVEHDSYAYVVLPASDLDDISEYRDEKPIKIIRQDDIAHIIRYKDDNVIAANIWQQQKVELTRHISAIGKMAILVQKEEGTKRISVSDPLQNQTTVELEFKKPIKIMSDPDQRLQISGQKILTIDVTNLKGNSYQFIVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3U3</accession>
    <name>D0Z3U3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001094</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306208.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001094"/>
    <dbReference type="EnsemblBacteria" id="EEZ40074">
        <property type="protein sequence ID" value="EEZ40074"/>
        <property type="gene ID" value="VDA_001094"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3121">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1607765at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018891" evidence="1">
        <location>
            <begin position="22"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="238" mass="27164" checksum="D82EBE6C61869405" modified="2010-01-19" version="1">MNLNKFLLTIGLASISISVQAFYVDSMVKFPQNNSGNGIFTVTSDLTRTEFINIEISKVLANENKIEKIPYTRENFPLWDLATSPGKLVLHPGEAKDIAVKFLCQKNCRNENSDLVYQVNFIPVNDPNKKNKKQKVNMLFGMAPYYIIPAKNPKYDYSYSFSKGNNELTIKNSGNSYLNFNVDNCKDKNIPEGKDCSVNYHLIANRERKIQIPEHLISHSTILRVANHDESFLKKNHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3U9</accession>
    <name>D0Z3U9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ATP synthase gamma chain</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">ATP synthase F1 sector gamma subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">F-ATPase gamma subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">atpG</name>
        <name evidence="10" type="ORF">VDA_001102</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the ATPase gamma chain family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306225.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001102"/>
    <dbReference type="EnsemblBacteria" id="EEZ40080">
        <property type="protein sequence ID" value="EEZ40080"/>
        <property type="gene ID" value="VDA_001102"/>
    </dbReference>
    <dbReference type="GeneID" id="57343437"/>
    <dbReference type="eggNOG" id="COG0224">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1701531at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042777">
        <property type="term" value="P:proton motive force-driven plasma membrane ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12151">
        <property type="entry name" value="F1-ATPase_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00815">
        <property type="entry name" value="ATP_synth_gamma_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035968">
        <property type="entry name" value="ATP_synth_F1_ATPase_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000131">
        <property type="entry name" value="ATP_synth_F1_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023632">
        <property type="entry name" value="ATP_synth_F1_gsu_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11693">
        <property type="entry name" value="PTHR11693"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00231">
        <property type="entry name" value="ATP-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00126">
        <property type="entry name" value="ATPASEGAMMA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52943">
        <property type="entry name" value="SSF52943"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01146">
        <property type="entry name" value="ATPsyn_F1gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00153">
        <property type="entry name" value="ATPASE_GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0139">CF(1)</keyword>
    <keyword evidence="4 9" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ40080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="290" mass="32447" checksum="367E81DE352CEFE6" modified="2010-01-19" version="1">MANAKEIRTKIASVQNTQKITSAMQMVAASKMRKVEENMALTRPYAANMRKVISHVASGSLEYQHPYLEEREVKRVAYIIISSDRGLCGGLNNNLFKKALADMRQWQESGVEVDTTLIGSKAISFFHRFGNVIAQTSGLGDKPKLEDILGPVNAMLEHFDQGKIDRLFLVFNEFVNTMVQKPQIVQLLPSPEIEKEANDEISASSRWDYIYEPDPKQILNELMLRYIESQVYQGTVESIACEQAARMVAMKAATDNAGQLINDLQLMYNKARQAAITQELSEIVAGAQAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3X7</accession>
    <name>D0Z3X7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001130</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306295.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001130"/>
    <dbReference type="EnsemblBacteria" id="EEZ40108">
        <property type="protein sequence ID" value="EEZ40108"/>
        <property type="gene ID" value="VDA_001130"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1661500at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="302" mass="34282" checksum="FCD413B92B2B0CE8" modified="2010-01-19" version="1">MDLNTVAIFAQVVECGSFTQAAEALELTKSTVSRKVAELESHLGVRLLTRSTRHITLTQEGELFYQSCAQMMDIISQAELEVTANQDQVRGRINIAMPVEVGQQVLIPYINEYLRQYPNVVIHLDLTNKPVELISEGIDLYVQIGPIEDSSLIARQFHSSHRILVASPEYLKQYGEINAPTDLKDPHYQIRIDNAARVNSAWQISQNEQEFHIELPHRIQVNTISAAADACVDSLGIALLPEFICLPHLETGRLVHLLPEWKMPEVPISLVYSQRNLMPKRLRLLIDFLMSKMEERHKLGSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z457</accession>
    <name>D0Z457_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Hexose phosphate transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_000313</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000313"/>
    <dbReference type="EnsemblBacteria" id="EEZ39295">
        <property type="protein sequence ID" value="EEZ39295"/>
        <property type="gene ID" value="VDA_000313"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2271">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000849">
        <property type="entry name" value="Sugar_P_transporter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002808">
        <property type="entry name" value="Hexose_phosphate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="116"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="159"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="186"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="247"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="291"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="320"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="350"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="385"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="416"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="20"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="458" mass="49745" checksum="B30F64D14DA2AD4D" modified="2010-01-19" version="1">MRKPTLDLPVSERKKMWFGPFIRSYLVVFVSYMVMYFIRKNFNIAQNDLISDYGMTMTQLGTIGLGFSITYGIGKTALNYWCDGKNSKNILPLGLLLSGFCMLGFGLVMGPSMGSFYMMIGLYALSGLFQSVGGSNSYSTITKWTSKKNRGTFLGMWNISHNIGGAGAAGVALFGANYFFDGNVAGMFIVPAIIAIVVAFIGFFMGSDSPEAYGLGTAEELFEEPVSEEDKAVSENKMSKLEIFKKYVLFNKVIWLLCFANVFLYVVRIGIDQWSTVYGYEVLGFDKETAISGFTMFETGALIGTCLWGFFSDLINGRRGLVACVALLGVIATLGFYQHADTIFAYQASLFALGFLVFGPQLLIGVAAVGFVPKQGIAVADGIKGTFAYLIGDSFAKLGLGLIADGTPIFGQTGWSGTFVALDTAAIICCSIMAVVAILEERKIHREKKEKKLAEANA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4B5</accession>
    <name>D0Z4B5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Chitinase</fullName>
            <ecNumber evidence="7">3.2.1.14</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_000371</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.14" evidence="7"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304179.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000371"/>
    <dbReference type="EnsemblBacteria" id="EEZ39353">
        <property type="protein sequence ID" value="EEZ39353"/>
        <property type="gene ID" value="VDA_000371"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3469">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3979">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1081028at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004568">
        <property type="term" value="F:chitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003610">
        <property type="entry name" value="CBM_fam5/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036573">
        <property type="entry name" value="CBM_sf_5/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032179">
        <property type="entry name" value="Cry22Aa_Ig-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16403">
        <property type="entry name" value="DUF5011"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00495">
        <property type="entry name" value="ChtBD3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51055">
        <property type="entry name" value="SSF51055"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019986" evidence="5">
        <location>
            <begin position="23"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="6">
        <location>
            <begin position="35"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="731" mass="79591" checksum="AECCC628252D3EFD" modified="2010-01-19" version="1">MTKMSAFKLNALALALSGFSFAANASDAMVNPQGNVVVGYWHNWCDGAGYQGGNAPCITLEETNPMYNIVDVSFMKVYSLADGRIPTFKLDPTIGLSEAEFIDQIKILNEQGRSVLIALGGADAHVELRMGDEQAFADEIIRLTDIYGFDGLDIDLEQTAIDAADNQIVIPAALRLVKDHYRAQGKNFLITMAPEFPYLKQNGKYIPYITGLEEYYDWINPQFYNQGGDGLWVDEENAWITQNNDAMKEKFIYYISDSLANGTRGFHKIPHDKLIFGIPTNNDAAASGFVKNPQDLFNAFDRLKAQAQPLRGVMTWSINWDIGTNSAGQNYNSSFINAYGPYIHNQTPPPPVEGKPVFSGLIDARVQHKASFDPLSGVSATDKEDGNLTSSIVVEGSANTQVVGDYVLTYSVTDSDNHETKSPRKVTVFSLMPTITGIDNSTVKLGDTFDPLAGVSATDAEDGDLTDSIQVEGQVDTAKVGQYTLTYSITDSADQTVTAKRIITVNDGSIVCTPAWDASKTYIEGDVVSHNGKNWRAGWWTQGEEPGTTGQWGVWREVGNSDCDGEQPDPTLSVSIAGLSTHYTLVDGSASLRMTINSNISSSVTIKVKDLLGNTVSGGHFDGTVLGDKTITLALSHAKTGAHQVLLTAQTEQKTVEKNYTINLVEKDKPTPPPTDVPNYEAGFAYQEGDKVLGSDGNVYQCKPWPYSGWCASASYAPATSQYWPDAWDKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4C6</accession>
    <name>D0Z4C6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000382</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304209.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39364">
        <property type="protein sequence ID" value="EEZ39364"/>
        <property type="gene ID" value="VDA_000382"/>
    </dbReference>
    <dbReference type="GeneID" id="57343244"/>
    <dbReference type="eggNOG" id="COG2244">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="556236at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="154"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="179"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="232"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="264"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="303"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="335"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="368"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="395"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="430" mass="49457" checksum="38CB481107909DD4" modified="2010-01-19" version="1">MEQQSTCAPEPVDSLTKLQKAFITGIWATLASISVSFLFKVWLAQWVAKSDLALFNSVVDIISLSLILMTGFRSSMVVSFSQTNNDRDIINIFRFSLIVMVLITWGIVIPYIKHELHINVSYFEMVGVIIGMGMKVYFTNLIAMYRLYHISNKVTWIEPISNVLIFLVCYYGLHFTALASLFYSMMLSSLIVAHYMYWQRRKEIATKPITNVQLNSDMINYMKKSFTASLEAGASILMIYIAVLLTITHFSIDELGDFQVVVRPIFTYMTMLFVFPIYRFVLPELSVCVRQGKHDEIKAIRRWVFKLAFIVSAVFFALMLFWGNEIVMFIFPPQYKGAVLVLFHFSMFFVFMMLNAYQLAYIKAHGKFTLSLMIRISGIVTLVAAYYILSEFTANVVSIIVALCLGYVMMFILSTIEEKKILRGYQQQDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4F0</accession>
    <name>D0Z4F0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative transcriptional regulator LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000406</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304278.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000406"/>
    <dbReference type="EnsemblBacteria" id="EEZ39388">
        <property type="protein sequence ID" value="EEZ39388"/>
        <property type="gene ID" value="VDA_000406"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="846433at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="4"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="301" mass="34957" checksum="04120CA0AF77FFB6" modified="2010-01-19" version="1">MKLPPLRAVQCFETVARLNSFSLAAQQLHITQSAVSHQVKQLEEYLGEELFIRQGRKLTLSSVGEQYFDEVSNSLQTISQASQRLREGEDGKIRLALYSSLAVKWLIPRLENLRQLHPEIDLSLNMMADEPEFSDRVADCFITAYPPKRNFVKEFLYDEHLYPFCSQQIWQQIKDKPLPDALWQHNLLSVSTIFLHGKPGQDWYEWCRLGGFELPAEVTMSHFSHMLLAAEAARYHQGITFLNDFFTTDQERQQYLIRIPMHDLPTGDSLYFVYKKSRAKQKGIQTLSRWLKAQCLQIGQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4J2</accession>
    <name>D0Z4J2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative lipoprotein NlpC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000450</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C40 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000450"/>
    <dbReference type="MEROPS" id="C40.004"/>
    <dbReference type="EnsemblBacteria" id="EEZ39430">
        <property type="protein sequence ID" value="EEZ39430"/>
        <property type="gene ID" value="VDA_000450"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0791">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000064">
        <property type="entry name" value="NLP_P60_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00877">
        <property type="entry name" value="NLPC_P60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51935">
        <property type="entry name" value="NLPC_P60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018846" evidence="2">
        <location>
            <begin position="27"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="NlpC/P60" evidence="3">
        <location>
            <begin position="64"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="186" mass="20768" checksum="8F3FDA1B8C62AB4D" modified="2010-01-19" version="1">MIKTNRNKTFLFVGLLVSLVTGCSSTEGVQSESNKQASANYTENQPDQIGNLIASLNQGNKTKPQASGGFSSVYRSWKGTPYRYGGTTRRGIDCSAFVQVGYSNVYDLALPRTTAEQVKKGKKISRANAREGDLVFFRTGRNSRHVGIYLGNSEFLHASRSKGVIISSLDNPYWRRTFWQIRRMPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-06-02" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4J8</accession>
    <name>D0Z4J8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000456</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39436">
        <property type="protein sequence ID" value="EEZ39436"/>
        <property type="gene ID" value="VDA_000456"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031NNQ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="56" mass="6786" checksum="E3D53260081CB444" modified="2010-01-19" version="1">MAKLDQKFSKGSKSKFKTDYDDDFQDFGNASRKKKRRVTRQRYDGPEFSNFDYDEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4N7</accession>
    <name>D0Z4N7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Beta-lactamase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_000495</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the metallo-beta-lactamase superfamily. Type III sulfatase family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304523.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000495"/>
    <dbReference type="EnsemblBacteria" id="EEZ39475">
        <property type="protein sequence ID" value="EEZ39475"/>
        <property type="gene ID" value="VDA_000495"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2015">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="775108at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018741">
        <property type="term" value="F:alkyl sulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018909">
        <property type="term" value="P:dodecyl sulfate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07710">
        <property type="entry name" value="arylsulfatase_Sdsa1-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038536">
        <property type="entry name" value="Alkyl/aryl-sulf_dimr_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029229">
        <property type="entry name" value="Alkyl_sulf_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029228">
        <property type="entry name" value="Alkyl_sulf_dimr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044097">
        <property type="entry name" value="Bds1/SdsA1_MBL-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036527">
        <property type="entry name" value="SCP2_sterol-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14864">
        <property type="entry name" value="Alkyl_sulf_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14863">
        <property type="entry name" value="Alkyl_sulf_dimr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55718">
        <property type="entry name" value="SSF55718"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019412" evidence="5">
        <location>
            <begin position="20"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="domain" description="Lactamase_B" evidence="6">
        <location>
            <begin position="123"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00033751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="651" mass="73051" checksum="2043FF552854EC70" modified="2010-01-19" version="1">MRYTLVALLGIMTVFNSYAQESKPASEATKAANQQVQNSLPFSNKQDFEDAQKGFIAKEEPLTIKDAKGNVVWDLEEYKKYIGLDKAAPDTVNPSLWRNAQLNMINGLFKVTDGIYQIRGYDLSNITFIEGKTGWIVFDPLISRETAKAALDFINKELGERPVVAIIYSHSHIDHFGGVKGLVTDKDVEDGKVVVIASDGFTEHAVSENVIAGNAMGRRAIYMYGALLPRNASGGVNGGLGQTTSTGMATLIKPTDLIKETGEVRTIDGVKMVFQFTPGTEAPTEINTWFPEKKALWMAENSTNTMHNILTLRGAQVRDALKWATYLNETIELWGNEVEVKFQSHHWPMWGEKRIVDYLKKQRDIYKYIHDQSVRLMNQGYVGSEISEMITLPSELENNWSTRGYYGTLRHNSRAVYQRYMGWYTGNPSDLNNLPPVDAAKKYVEYMGGEQAVIDKAQKDFDKGNYRWVAEVLKQAVFASPDNAKAKALLADTYEQLGYQAESGPWRSVYLQGAYELRNGVPTSGGTQTATPDIIKNMPPEMYFDYLAIRLNPEKAAGKNFIINVDFTDLKEEYTLYVENSVLNYSNKINKEPNVSLSLTKATLDKIQLGEITIEQAIKNGDVKLTGDKAVLEDFVGMLDTFNFWFNVVTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4P4</accession>
    <name>D0Z4P4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000502</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000502"/>
    <dbReference type="EnsemblBacteria" id="EEZ39482">
        <property type="protein sequence ID" value="EEZ39482"/>
        <property type="gene ID" value="VDA_000502"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="293" mass="33436" checksum="0B8E3CF774822665" modified="2010-01-19" version="1">MRALAEVVNDGVCADDKLSDLYARVQRRPVNREADTLVFENTMMALHNLSSLKSMNENARDKYDICRSAIISWYYSIYFSASAMVAASSGSIQETHTATAKVWQSDIAEKELIPYPFNLLLTSLVSKTADAEITAYRGSNRYDLNDRAYDNETAHGALVSYLKGTHGYKKWETEERVRTSRDFKALGVDNFRTKAAREVRDRALEKGQVNFLIQAFRYRGKANYRDSIFLSYGDNNEATIEEFIQDLYDVSIGFIRSTSHYCSRRVERGAWAEFVEDISDNSRLSIDPIVLEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4Q8</accession>
    <name>D0Z4Q8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">NAD-dependent malic enzyme</fullName>
            <ecNumber evidence="10">1.1.1.38</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_000516</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="6">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="6">Divalent metal cations. Prefers magnesium or manganese.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the malic enzymes family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.38" evidence="10"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000516"/>
    <dbReference type="EnsemblBacteria" id="EEZ39496">
        <property type="protein sequence ID" value="EEZ39496"/>
        <property type="gene ID" value="VDA_000516"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0281">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004471">
        <property type="term" value="F:malate dehydrogenase (decarboxylating) (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008948">
        <property type="term" value="F:oxaloacetate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015884">
        <property type="entry name" value="Malic_enzyme_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012301">
        <property type="entry name" value="Malic_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037062">
        <property type="entry name" value="Malic_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012302">
        <property type="entry name" value="Malic_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001891">
        <property type="entry name" value="Malic_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00390">
        <property type="entry name" value="malic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03949">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000106">
        <property type="entry name" value="ME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00072">
        <property type="entry name" value="MALOXRDTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01274">
        <property type="entry name" value="malic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00919">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00331">
        <property type="entry name" value="MALIC_ENZYMES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="malic" evidence="9">
        <location>
            <begin position="88"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="Malic_M" evidence="8">
        <location>
            <begin position="278"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="111"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="182"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="253"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="254"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="277"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000106-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000106-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ39496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="538" mass="59743" checksum="2D43392F081BF6E6" modified="2010-01-19" version="1">MTVGKYLRWKDEQGNAFRPVSLTGTELLNDRTLNKSTAFTYEEREAFQLNGLLPPRVQTFEDQLNRVYDGFRSASTDIEKYLFLRALQDRNETLFYALLSRHVEEMTPIIYTPTVGKACQEFSHRYQKARGLYVTEDNVSQMGEMARHFAGKEIKIIVATDSQGILGIGDQGVGGMGIPIGKLSLYTLGAGIHPAHCLPIALDVGTDNQELLNDPMYLGIPRKRLRGEEYKRFIKRFVKQVKRHFPKAVLQWEDFSKSNAFDNLSDYEDVLPSFNDDIQGTGSVVLAGVLGACRMKKESLVDQTFVVYGAGAGGVGVADQIYAGLLKEGCTHQAARDKIFILDSQGLVFEDRDGLDEYKKRYAKSRDIAEGWHTEELGKVTLTELLNNYPVTVLLGTSGIGGAFKAEHVQKMMEYTPRPMIFPLSNPTANCEALPVDIYQWSDGQAIVATGSPFGNVTYNGFEYRIGQGNNVFIFPGVGLASIVSKTQKITLDMFTTASYALAECVTEDDLAEGSVYPHIRDLKSVSITVAKAILNHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4R7</accession>
    <name>D0Z4R7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000525</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304627.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39505">
        <property type="protein sequence ID" value="EEZ39505"/>
        <property type="gene ID" value="VDA_000525"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5033FJR">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1704507at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="277" mass="31820" checksum="33E2AB02A2B1E108" modified="2010-01-19" version="1">MDANDNLKTCHDEVIGILVVKDGNGFIRRTKDHQQRFVSIPYYLSNQTAFKRPILFVTESPHVEEFKVGQVYDCLTQELVHARPVNGVTGNNIRQYLIGLLLGIKLTLEDGYYPIIVINALQEQCSLGQDTALYRTRNFIKYWPSRIEYLQKRLQELDPIIAINACTAGDFYLMREGKMTQTKAFSSGRRQDFEQAFSLLLFEEFGYSDAVNSSDDKLVFMGSFDLAGLVMKELYDAYNPRHILLKKSTHPSAWARSNQLPQLRECGTQLRTLFKIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4Z7</accession>
    <name>D0Z4Z7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DDE_Tnp_1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39214">
        <property type="protein sequence ID" value="EEZ39214"/>
        <property type="gene ID" value="VDA_000230"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3385">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_1" evidence="1">
        <location>
            <begin position="17"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="262" mass="30836" checksum="C25FBC226D90B9F4" modified="2010-01-19" version="1">MTNSWLKSAKLPHWNGLTLLSVDGVVWRTTDNQENEEAFSRQKGTQYPQVRMVCQMELSSHLITASAFDNYNTNEMVLAEKLTEMTPDHSVTMFDKGLYSLGLLDKWHATGTGRHWLIPLKKNVQYEVIWPLGRNDKLILLHSNPRARKLWTNLPSSITARLVTRKIKGKDYQVLTSMIDPLRYPSKDIVALYEHRWEIELGYREQKQYMLGNRLTLRSRLPELVRQELWGILLTYNLIRYQMVELCFNLKENYLPYQLSFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z555</accession>
    <name>D0Z555_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Site-specific recombinase resolvase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_000105</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000105"/>
    <dbReference type="EnsemblBacteria" id="EEZ39089">
        <property type="protein sequence ID" value="EEZ39089"/>
        <property type="gene ID" value="VDA_000105"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1961">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000150">
        <property type="term" value="F:DNA strand exchange activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006118">
        <property type="entry name" value="Recombinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006119">
        <property type="entry name" value="Resolv_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036162">
        <property type="entry name" value="Resolvase-like_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00239">
        <property type="entry name" value="Resolvase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00857">
        <property type="entry name" value="Resolvase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53041">
        <property type="entry name" value="SSF53041"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00397">
        <property type="entry name" value="RECOMBINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00398">
        <property type="entry name" value="RECOMBINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51736">
        <property type="entry name" value="RECOMBINASES_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0229">DNA integration</keyword>
    <keyword evidence="3" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Resolvase/invertase-type recombinase catalytic" evidence="6">
        <location>
            <begin position="18"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-serine intermediate" evidence="4 5">
        <location>
            <position position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR606118-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="225" mass="25655" checksum="3AD19629CD828756" modified="2010-01-19" version="1">MAHLIGSLFKCHMGLDLYIFGYLRASTADQDAKRAKSILSSFISDKGLRIASWYIENESGTSLQRPELLHLLEDAAIGDAILIEQIDRLSRLDEASWFKLKEMLHEKELKVISLDLPTSHIALSPQITDEFTGSMIKAINNMMMDMLAAIARKDYQDRRRRQAEGIKKAKAEGKYKGRRPNLELHDKIYQLRVVNRLSISDTAKLTNVSNRTVIRVAKKLIRENS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVM2</accession>
    <name>D0YVM2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">LYZ2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001591</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298335.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40564">
        <property type="protein sequence ID" value="EEZ40564"/>
        <property type="gene ID" value="VDA_001591"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2992">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="682655at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004040">
        <property type="term" value="F:amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002901">
        <property type="entry name" value="MGlyc_endo_b_GlcNAc-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01832">
        <property type="entry name" value="Glucosaminidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LYZ2" evidence="1">
        <location>
            <begin position="134"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="279" mass="31508" checksum="7D839F70365245E4" modified="2010-01-19" version="1">MTRITTVGVITLVAAVSAAAIYKAKVRNDHQVDLAPSPIMMEQILNNKPNFAVIDSEADKKKAFFQYLTPDIVRENNAILKDRENLLALMKKPEKMTEKNAFLIRLSNHYAWPMPAHDEKTSEPISQQWLTGLLDRVDILPVPLVLSQAAIESGWGTSRFAVEGDNYFGLWCYSPGCGLAPLEEKDSKNYHEVARFNSLQHAVDAYFLNMNTNPEFQPLRDKRAQLRAEGLPLTATALAPELIHYSQIGQRYIEEINTILHQDGHFMLIPEVPKKEPTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVN4</accession>
    <name>D0YVN4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 16">Aconitate hydratase B</fullName>
            <ecNumber evidence="5 16">4.2.1.3</ecNumber>
            <ecNumber evidence="6 16">4.2.1.99</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">2-methylisocitrate dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">VDA_001199</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 23">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 16">
            <text>(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = 2-methyl-cis-aconitate + H2O</text>
            <dbReference type="Rhea" id="RHEA:17941"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57429"/>
            <dbReference type="ChEBI" id="CHEBI:57872"/>
            <dbReference type="EC" id="4.2.1.99"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15 16">
            <text>citrate = D-threo-isocitrate</text>
            <dbReference type="Rhea" id="RHEA:10336"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:16947"/>
            <dbReference type="EC" id="4.2.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="17">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="17">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 16">Carbohydrate metabolism; tricarboxylic acid cycle; isocitrate from oxaloacetate: step 2/2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Organic acid metabolism; propanoate degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 16">Belongs to the aconitase/IPM isomerase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.3" evidence="5 16"/>
    <dbReference type="EC" id="4.2.1.99" evidence="6 16"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297623.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001199"/>
    <dbReference type="EnsemblBacteria" id="EEZ40177">
        <property type="protein sequence ID" value="EEZ40177"/>
        <property type="gene ID" value="VDA_001199"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1049">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="32104at2"/>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER00718"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00946"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047456">
        <property type="term" value="F:2-methylisocitrate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003994">
        <property type="term" value="F:aconitate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047780">
        <property type="term" value="F:citrate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01576">
        <property type="entry name" value="AcnB_Swivel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.19.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.499.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015931">
        <property type="entry name" value="Acnase/IPM_dHydase_lsu_aba_1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001030">
        <property type="entry name" value="Acoase/IPM_deHydtase_lsu_aba"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015928">
        <property type="entry name" value="Aconitase/3IPM_dehydase_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018136">
        <property type="entry name" value="Aconitase_4Fe-4S_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036008">
        <property type="entry name" value="Aconitase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004406">
        <property type="entry name" value="Aconitase_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015933">
        <property type="entry name" value="Aconitase_B_HEAT-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036288">
        <property type="entry name" value="Aconitase_B_HEAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015929">
        <property type="entry name" value="Aconitase_B_swivel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015932">
        <property type="entry name" value="Aconitase_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00330">
        <property type="entry name" value="Aconitase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06434">
        <property type="entry name" value="Aconitase_2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11791">
        <property type="entry name" value="Aconitase_B_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036687">
        <property type="entry name" value="AcnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53732">
        <property type="entry name" value="SSF53732"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74778">
        <property type="entry name" value="SSF74778"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00117">
        <property type="entry name" value="acnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00450">
        <property type="entry name" value="ACONITASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01244">
        <property type="entry name" value="ACONITASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 17" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="12 17" id="KW-0408">Iron</keyword>
    <keyword evidence="13 17" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="14 16 22" id="KW-0456">Lyase</keyword>
    <keyword evidence="10 17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="9 16" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Aconitase_B_N" evidence="21">
        <location>
            <begin position="4"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="Aconitase_2_N" evidence="20">
        <location>
            <begin position="168"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="domain" description="Aconitase" evidence="19">
        <location>
            <begin position="471"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="18">
        <location>
            <begin position="244"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="18">
        <location>
            <begin position="414"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="498"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="710"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="769"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="772"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="791"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="796"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00019379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRNR" id="PIRNR036687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR036687-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR036687-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF06434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF11791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="EEZ40177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="865" mass="93654" checksum="FA59008E7978B221" modified="2010-01-19" version="1">MLDAYRKHVAERAAEGVVPQPLNAELVVALIELLKNPPAGEEAFLVELLENRIPPGVDEAAYVKAGFLAAITQGEAQSPLVSKEKAAELLGTMQGGYNIEPLIRLLDDPSLAPIAATALSHTLLMFDAFYDVEEKAKAGNEFAQQVLQSWANADWFLQKPALAEKITLTVFKVSGETNTDDLSPAPDAWSRPDIPLHALAMLKNAREGIEPDQAGTVGPIAQIEALKALGHQLVYVGDVVGTGSSRKSATNSVLWFMGDDIPYVPNKRAGGYVLGGKIAPIFFNTMEDAGALPIEVDVSQLAMGDVIDVYPFKGEVRRHDSDELVATFKLKTDVLIDEVRAGGRIPLIIGRGLTDRARQSLGLPASDVFRRPAPVADSGKGYTLAQKMVGKACGVEGIRPGTYCEPKMTTVGSQDTTGPMTRDELKDLACLGFSADLTMQSFCHTSAYPKPIDVNTHHTLPDFIMNRGGVSLRPGDGVIHSWLNRMLLPDTVGTGGDSHTRFPLGISFPAGSGLVAFAAATGVMPLDMPESILVRFKGEMQPGITLRDLVHAIPYFAIQQGLLTVEKAGKINEFSGRVLEIEGVEHLTVEQAFELSDASAERSAAGCTVKLSQQSVSEYLESNIVMLKWMISQGYGDRRTLERRITAMQEWLDNPSLMTADSDAEYAHIIEIDLAEIKEPILCAPNDPDDARLLSEVQGTEIDEVFIGSCMTNIGHFRAAGKLLEKFGGQLNTRMWVAPPTKMDKDQLTEEGYYGIFGRAGVRIETPGCSLCMGNQARVADNATVMSTSTRNFPNRLGTGANVYLSSAELAAVGAVLGHIPTVEEYLEFAKQIDATAADTYRYLNFHRMEQYTKPAAEVIMVQPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVN6</accession>
    <name>D0YVN6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">D-glycerate transporter, predicted</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001201</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001201"/>
    <dbReference type="EnsemblBacteria" id="EEZ40179">
        <property type="protein sequence ID" value="EEZ40179"/>
        <property type="gene ID" value="VDA_001201"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2610">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015128">
        <property type="term" value="F:gluconate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003474">
        <property type="entry name" value="Glcn_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30354">
        <property type="entry name" value="PTHR30354"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02447">
        <property type="entry name" value="GntP_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="154"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="182"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="224"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="259"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="309"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="329" mass="33438" checksum="24BD529FCFD422A6" modified="2010-01-19" version="1">MGETRALLALALATMILTAVGVFVDVAVITVAPIALAIARRADISKMAILLAMVGGGKAGNVMSPNPNSIAAADAFNVPLTSVMAAGVIPGLCGMILAYFIAKKLVNKGSKVQEHEVVAVDMSRLPSFKAAIVAPLVAIALLSLRPIAGINIDPLIALPLGGLLGAIAMKRHRDTNHFAVSGLTRMAPVAVMLLGTGTLAGIIANSGLKNGLIEVLTASGLPSYLLAPVSGAMMSLATASTTAGTAVASSVFSQTILDLGVPALAGAAMIHAGATVFDHMPHGSFFHATGGSVHMDMKERLKLIPYESAVGLMIAVVSTLIFGVFGLFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVP0</accession>
    <name>D0YVP0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Ammonium transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_001205</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ammonia transporter channel (TC 1.A.11.2) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297635.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001205"/>
    <dbReference type="EnsemblBacteria" id="EEZ40183">
        <property type="protein sequence ID" value="EEZ40183"/>
        <property type="gene ID" value="VDA_001205"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0004">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="562287at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008519">
        <property type="term" value="F:ammonium transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029020">
        <property type="entry name" value="Ammonium/urea_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018047">
        <property type="entry name" value="Ammonium_transpt_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019879">
        <property type="entry name" value="Ammonium_transptr_marine"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024041">
        <property type="entry name" value="NH4_transpt_AmtB-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00909">
        <property type="entry name" value="Ammonium_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03644">
        <property type="entry name" value="marine_trans_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01219">
        <property type="entry name" value="AMMONIUM_TRANSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0924">Ammonia transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="128"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="165"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="206"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="243"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="269"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="293"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="327"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="350"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="Ammonium_transp" evidence="9">
        <location>
            <begin position="18"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ40183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="409" mass="43085" checksum="AF1609B328501CB1" modified="2010-01-19" version="1">MELSLTVTELRYALDTFFFLMSGALVMWMAAGFAMLEAGLVRSKNTTEILTKNICLYAIACTAFLVVGYNIMYVNNSEGGFFPSIGTLIGSQSPDADHSLESDFFFQVVFVATAMSVVSGAVAERMKLWSFLIFSVVMTAFIYPVEGYWTWGGGFLSESGFSDFAGSGIVHMAGASAALAGVLLLGSRKGKYGKNGEIYPIPGSNMPLATLGTFILWFGWFGFNGGSQLMISDFENATAVGKIFLNTNAAAAAGAIAALLVCKTTWGKADLTMILNGALAGLVAITADPLSPSPLVAVAIGVAAGALVVFSIVALDKVKVDDPVGAISVHGVCGLFGLLVVPFSNGDASFMTQLFGAAVIFGWVFGMSFAVWGILKLTLGIRVSEDEELEGMDVHDCGIDAYPEFVSVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW19</accession>
    <name>D0YW19_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RNA polymerase sigma factor RpoS</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Sigma S</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Sigma-38</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpoS</name>
        <name evidence="9" type="ORF">VDA_001279</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Interacts with the RNA polymerase core enzyme.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the sigma-70 factor family. RpoS subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297774.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001279"/>
    <dbReference type="EnsemblBacteria" id="EEZ40257">
        <property type="protein sequence ID" value="EEZ40257"/>
        <property type="gene ID" value="VDA_001279"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0568">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1565734at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00959">
        <property type="entry name" value="Sigma70_RpoS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000943">
        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009042">
        <property type="entry name" value="RNA_pol_sigma70_r1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007624">
        <property type="entry name" value="RNA_pol_sigma70_r3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012761">
        <property type="entry name" value="RNA_pol_sigma_RpoS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00140">
        <property type="entry name" value="Sigma70_r1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04539">
        <property type="entry name" value="Sigma70_r3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00046">
        <property type="entry name" value="SIGMA70FCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02394">
        <property type="entry name" value="rpoS_proteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00715">
        <property type="entry name" value="SIGMA70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00716">
        <property type="entry name" value="SIGMA70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="4 5" id="KW-0804">Transcription</keyword>
    <keyword evidence="1 5" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RNA_pol_sigma70" evidence="7">
        <location>
            <begin position="118"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_sigma70" evidence="8">
        <location>
            <begin position="287"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="5">
        <location>
            <begin position="288"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="26"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Sigma-70 factor domain-1" evidence="5">
        <location>
            <begin position="56"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Sigma-70 factor domain-2" evidence="5">
        <location>
            <begin position="94"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Sigma-70 factor domain-3" evidence="5">
        <location>
            <begin position="174"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Sigma-70 factor domain-4" evidence="5">
        <location>
            <begin position="262"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Interaction with polymerase core subunit RpoC" evidence="5">
        <location>
            <begin position="118"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="27"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ40257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="333" mass="37670" checksum="EC7D8051942A0772" modified="2010-01-19" version="1">MSKSSTVTNLDSFDFDDEIELDTGDAVNAKNTATADDDSAEELSSGSNNQAQKVLDATQLYLGEIGFSPLLTAEEEVLYARRALRGDDVARKRMIESNLRLVVKISRRYSNRGLALLDLVEEGNLGLIRAVEKFDPERGFRFSTYATWWIRQTIERAIMNQTRTIRLPIHVVKELNVYLRTARELAQKLDHEPTAEDIAIQLEKPVDDVNRMLRLNERVSSVDNPISGDADKALLDIIPDEKGGTPEVSTQTDDIKSSIVDWLDELNPKQREVLARRFGLLGYEASTLEDVGREIGLTRERVRQIQVEGLRRLRDMLTHEGLSIESLFDPDEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW90</accession>
    <name>D0YW90_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase</fullName>
            <ecNumber evidence="6 7">6.3.2.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">D-alanyl-D-alanine-adding enzyme</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">murF</name>
        <name evidence="11" type="ORF">VDA_001172</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>ATP + D-alanyl-D-alanine + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine</text>
            <dbReference type="Rhea" id="RHEA:28374"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57822"/>
            <dbReference type="ChEBI" id="CHEBI:61386"/>
            <dbReference type="ChEBI" id="CHEBI:83905"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6 7">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the MurCDEF family. MurF subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.10" evidence="6 7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297568.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001172"/>
    <dbReference type="EnsemblBacteria" id="EEZ40150">
        <property type="protein sequence ID" value="EEZ40150"/>
        <property type="gene ID" value="VDA_001172"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0770">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1861122at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047480">
        <property type="term" value="F:UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008766">
        <property type="term" value="F:UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02019">
        <property type="entry name" value="MurF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000713">
        <property type="entry name" value="Mur_ligase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035911">
        <property type="entry name" value="MurE/MurF_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005863">
        <property type="entry name" value="UDP-N-AcMur_synth"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01225">
        <property type="entry name" value="Mur_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63418">
        <property type="entry name" value="SSF63418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01143">
        <property type="entry name" value="murF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6 7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1 6 7" id="KW-0132">Cell division</keyword>
    <keyword evidence="2 6 7" id="KW-0133">Cell shape</keyword>
    <keyword evidence="5 6 7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 6 7" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase" evidence="8">
        <location>
            <begin position="24"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_M" evidence="10">
        <location>
            <begin position="110"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="9">
        <location>
            <begin position="317"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="111"/>
            <end position="117"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ40150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="460" mass="49009" checksum="235D6708B973B391" modified="2010-01-19" version="1">MISVSLASLAQAVEGQLIGSDTTISEVSTDTRNIAAQTLFVALKGERFDAHDFCQTAKDNGAVALLVSRHLPVELPQILVKDTRIALGLLGAWLKAQLTQQCGLQTLALTGSCGKTTVKEMCAAILATKGKVLATAGNFNNDIGAPLTLLRLTPEYQYAVIELGANHLGEISYTTNLVKPDVALINNLAAAHLEGFGSLKGVAKAKGEIFEGLAKGATAVINLASNDRELWAPLLADKNVITFSSEEQADFFASDIELDSDGYPHFELHSPQGSVAIHLSQLGLHNVSNALAAAALTSVLGATLAEIKQGLETATNVKGRVAVSQPMVGLRVIDDTYNASVASVKAAIDLLASYQGQRWFILGDMAELGEESENLHREVGLYAQTKGLDKVMTFGKASAVVSELNHGQHFADKQPLIAMVNELLNDQINQQNPLEVTVLVKGARSSRMEEVVTALQEYKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWH5</accession>
    <name>D0YWH5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Magnesium and cobalt efflux protein CorC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001434</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298057.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001434"/>
    <dbReference type="EnsemblBacteria" id="EEZ40408">
        <property type="protein sequence ID" value="EEZ40408"/>
        <property type="gene ID" value="VDA_001434"/>
    </dbReference>
    <dbReference type="GeneID" id="57339641"/>
    <dbReference type="eggNOG" id="COG4535">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1155802at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04590">
        <property type="entry name" value="CBS_pair_CorC_HlyC_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044751">
        <property type="entry name" value="Ion_transp-like_CBS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005170">
        <property type="entry name" value="Transptr-assoc_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03471">
        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01091">
        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0129">CBS domain</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="CBS" evidence="4">
        <location>
            <begin position="71"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="4">
        <location>
            <begin position="136"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="290" mass="33157" checksum="5BB092F7E79B19A5" modified="2010-01-19" version="1">MNDDNTQNSEGPSRKSFFERIGQLFQGEPQNREELVEVFRDSEENALIDHDTRDMLEGVMEISEMRVRDIMIPRSQMITIERSQKLEDLVDLIVDAQHSRYPVISDDKDHVEGILLAKDLLRYLLPDSDAFDIDKVLRPAVVVPESKRVDRLLKEFREERYHMAIVVDEFGGVSGVITIEDILEQIVGEIEDEFDDDEEQDIRQLSKHTYSVKALTTIEDFNELFHTNFSDEEVDTIGGLVMTSFGHLPSRGEVVELDGYAFKVTAADNRRVIQLQVTVPNDAQLPTTSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWR8</accession>
    <name>D0YWR8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cell division inhibitor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001463</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001463"/>
    <dbReference type="EnsemblBacteria" id="EEZ40437">
        <property type="protein sequence ID" value="EEZ40437"/>
        <property type="gene ID" value="VDA_001463"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1090">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013549">
        <property type="entry name" value="DUF1731"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010099">
        <property type="entry name" value="SDR39U1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08338">
        <property type="entry name" value="DUF1731"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01777">
        <property type="entry name" value="yfcH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="2">
        <location>
            <begin position="4"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1731" evidence="3">
        <location>
            <begin position="252"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="303" mass="33781" checksum="ACF32B48D1971B0B" modified="2010-01-19" version="1">MMNILVTGGTGFIGKALLRHLSHNQITVLSRSPLKAYDSLGHHIKIIENLESYENLDQFDAVINLAGEPIMNKRWTASQKELICRSRWALTQSLVDKIKAGSNPPHTFISGSAVGIYGNTGPEKITEESEYLTHPDDFAQHVCMRWEKIAHQAQSEQTRVCLLRTGIVLAKHGGALAKMLPAYQLGLGGKLGNGQQYFPWIHLNDMVKGILYLLNHQDLNGVFNFTAPNSVTNQEFSKTLAHVVKRPHLLTTPAWLLKTVLGQSSSLLLDSQNIYPEHLIQAGFHFVYPTLQPALEHTLAQQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWW8</accession>
    <name>D0YWW8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytidylate kinase</fullName>
            <shortName evidence="8">CK</shortName>
            <ecNumber evidence="8">2.7.4.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Cytidine monophosphate kinase</fullName>
            <shortName evidence="8">CMP kinase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">cmk</name>
        <name evidence="10" type="ORF">VDA_001801</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + CMP = ADP + CDP</text>
            <dbReference type="Rhea" id="RHEA:11600"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58069"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.25"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 8">
            <text>ATP + dCMP = ADP + dCDP</text>
            <dbReference type="Rhea" id="RHEA:25094"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57566"/>
            <dbReference type="ChEBI" id="CHEBI:58593"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.25"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the cytidylate kinase family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.25" evidence="8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298727.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001801"/>
    <dbReference type="EnsemblBacteria" id="EEZ40769">
        <property type="protein sequence ID" value="EEZ40769"/>
        <property type="gene ID" value="VDA_001801"/>
    </dbReference>
    <dbReference type="GeneID" id="57342084"/>
    <dbReference type="eggNOG" id="COG0283">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="776861at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036430">
        <property type="term" value="F:CMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036431">
        <property type="term" value="F:dCMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006220">
        <property type="term" value="P:pyrimidine nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02020">
        <property type="entry name" value="CMPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00238">
        <property type="entry name" value="Cytidyl_kinase_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003136">
        <property type="entry name" value="Cytidylate_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011994">
        <property type="entry name" value="Cytidylate_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02224">
        <property type="entry name" value="Cytidylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00017">
        <property type="entry name" value="cmk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cytidylate_kin" evidence="9">
        <location>
            <begin position="8"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="12"/>
            <end position="20"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ40769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="225" mass="24430" checksum="E3E9C7BAD49C389C" modified="2010-01-19" version="1">MSTHAPVITVDGPSGAGKGTLCMLLAEKLGWNLLDSGAIYRVLALAAIHHDVDLESEDALVPLAANLDVQFVAEGELVKVILEGEDVSNTLRTEKVGNTASKVAALPRVREALLRRQRAFSEAPGLVADGRDMGTVVFPSAEVKIFLDASAEERANRRMNQLQKKGLDVNFDSLLSEIQERDYRDRNRAVAPLRPAEDALTIDSTELTIEEVLAQVVAFAESKLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX29</accession>
    <name>D0YX29_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Vitamin B12 import system permease protein BtuC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">btuC</name>
        <name evidence="8" type="ORF">VDA_001888</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">The complex is composed of two ATP-binding proteins (BtuD), two transmembrane proteins (BtuC) and a solute-binding protein (BtuF).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298881.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001888"/>
    <dbReference type="EnsemblBacteria" id="EEZ40856">
        <property type="protein sequence ID" value="EEZ40856"/>
        <property type="gene ID" value="VDA_001888"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4139">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1283908at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090482">
        <property type="term" value="F:vitamin transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015889">
        <property type="term" value="P:cobalamin transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01004">
        <property type="entry name" value="BtuC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037294">
        <property type="entry name" value="ABC_BtuC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023691">
        <property type="entry name" value="ABC_transptr_BtuC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000522">
        <property type="entry name" value="ABC_transptr_permease_BtuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30472">
        <property type="entry name" value="PTHR30472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01032">
        <property type="entry name" value="FecCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81345">
        <property type="entry name" value="SSF81345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="16"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="62"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="91"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="149"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="189"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="238"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="275"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="305"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ40856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="331" mass="35705" checksum="44F802376BA4D116" modified="2010-01-19" version="1">MQLNHLIQKQNARWRWAFIGAGVLLLLICLFSLAVGEIWIIPWSPESDLAKQLLLELRLPRLIAAISIGAALAVSGAVLQVLLANPLAEPGVLGISGGASLALVVLMFVLPVVPSPWISMLTAMVGALLFTFILVMLSRQRKVTTTRLLLIGVALGILSGAVVTWSFYFSDDLSMRQLMYWLMGSVAGVSWQQLILLVLLLPMIVWLCTQGRQLDILMLGELQAKQLGLDITKLRWKLILAISLLVGISVALGGVIGFVGLVIPHILRLALGTDNRFLVPLSALCGGLLLAFADTLSRIVLPAADLPVGVVTTTLGAPIFIWMLLSQAETK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXB2</accession>
    <name>D0YXB2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Transport ATP-binding protein CydC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_001652</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298448.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001652"/>
    <dbReference type="EnsemblBacteria" id="EEZ40625">
        <property type="protein sequence ID" value="EEZ40625"/>
        <property type="gene ID" value="VDA_001652"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4987">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="643917at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034775">
        <property type="term" value="P:glutathione transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014223">
        <property type="entry name" value="ABC_CydC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02868">
        <property type="entry name" value="CydC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="138"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="165"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="247"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="279"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="20"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="339"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="373"/>
            <end position="380"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ40625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="573" mass="63426" checksum="3F40E77982216544" modified="2010-01-19" version="1">MRDLIPYLKMYRKHWFGLTLGMILGLATILAAISLLTLSGWFIAASAVAGLTIARETFNYMLPGAGVRGFSMARTAGRWGERVVSHNATFKLLADLRIFFFRKLTPLIPGRQTNLRDADLLNRLVADVDAMDHVYLRLVSPLIVGVLSLVAVTVFLSWFDLTIGLTLGAILLALMLLLPVIFYRLGKRNGEALTYSKANYRITLLDWIQGQAELLLFNAEERYRVQAESEQQSLLTAQRKMANLTGVANAILMAATGWTLVLITWIAADGVGGNPPDPFVAMVAFATMASFELMMPVAGAFQYLGQTLTSARRLNEITEAKPDTPFDPNGYQAKAQGNIAIENISYTYYGSEQPVLKQVNLSLKQGEKLAILGRTGCGKSTLLQLLTRNWDPQQGQISLDGIPLPQWQEGALRNAMTVVSQRVDVFNGSLRENLLLAKPQASDAECVQALEQVGLTTLLDGQGLDTWLGEGGRQISGGERRRLGIARALLHDAPILLMDEPTEGLDRRTEQQILELLLEHAKDKTVIFITHRLIGLDEMDQICLMDEGRIIEHGKHQQLLAQKGRYAELCQRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXC3</accession>
    <name>D0YXC3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sodium/dicarboxylate symporter family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_001663</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298471.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001663"/>
    <dbReference type="EnsemblBacteria" id="EEZ40636">
        <property type="protein sequence ID" value="EEZ40636"/>
        <property type="gene ID" value="VDA_001663"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1823">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="781228at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001991">
        <property type="entry name" value="Na-dicarboxylate_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036458">
        <property type="entry name" value="Na:dicarbo_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42865">
        <property type="entry name" value="PTHR42865"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00375">
        <property type="entry name" value="SDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118215">
        <property type="entry name" value="SSF118215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="34"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="71"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="185"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="224"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="264"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="368"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="394"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="466" mass="48973" checksum="AEBFA996EA47569B" modified="2010-01-19" version="1">MTFSVIINLAIFLGLIAFLYHMQAKHYTFTKRVFAGLGLGIGFGAALQIFYGSGSEVIKTSIEYFDIVGVGYVRLLQMIIIPLVMVSIISAILKLNGGTSLGKISGLTIGVLIFTTMIAALVGILMSNLFGLTAEGLTAGAAEMARAKNLETTLSNVEAMSFAKLMIEFIPANPFLDMTGARRTSTIAVVIFSIFIGLSATGIARKKPEIFAQFESFIKVAQAIVMRMVTLVLRLTPFGVLALMTKVISGSNYADIINLANFVIASYAALILMFVIHLALVALVGINPIRHLKKIMPVLAFAFTSRTSAGSIPMNVQTQEKCLGIPSGIANFAASFGSTIGQNGCAGIYPAMLAIMIAPTVGINPMDFGFICTLIAIITVSSFGVAGIGGGATFAALIVLSAMDMPVALAGLLISIEPLIDMGRTALNVSGSITAGTITSKLMGQTDMNVFNSDEVVNLDGEESAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXD5</accession>
    <name>D0YXD5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Endonuclease III</fullName>
            <ecNumber evidence="10">4.2.99.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">DNA-(apurinic or apyrimidinic site) lyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">nth</name>
        <name evidence="12" type="ORF">VDA_001614</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-monophospho-2'-deoxyribonucleoside-DNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66592"/>
            <dbReference type="Rhea" id="RHEA-COMP:13180"/>
            <dbReference type="Rhea" id="RHEA-COMP:16897"/>
            <dbReference type="Rhea" id="RHEA-COMP:17067"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:136412"/>
            <dbReference type="ChEBI" id="CHEBI:157695"/>
            <dbReference type="ChEBI" id="CHEBI:167181"/>
            <dbReference type="EC" id="4.2.99.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="10">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the Nth/MutY family.</text>
    </comment>
    <dbReference type="EC" id="4.2.99.18" evidence="10"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298380.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001614"/>
    <dbReference type="EnsemblBacteria" id="EEZ40587">
        <property type="protein sequence ID" value="EEZ40587"/>
        <property type="gene ID" value="VDA_001614"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0177">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1381897at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140078">
        <property type="term" value="F:class I DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019104">
        <property type="term" value="F:DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00942">
        <property type="entry name" value="Nth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004036">
        <property type="entry name" value="Endonuclease-III-like_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003651">
        <property type="entry name" value="Endonuclease3_FeS-loop_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004035">
        <property type="entry name" value="Endouclease-III_FeS-bd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023170">
        <property type="entry name" value="HhH_base_excis_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000445">
        <property type="entry name" value="HhH_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005759">
        <property type="entry name" value="Nth"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10576">
        <property type="entry name" value="EndIII_4Fe-2S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00633">
        <property type="entry name" value="HHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00525">
        <property type="entry name" value="FES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="SSF48150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01083">
        <property type="entry name" value="nth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00764">
        <property type="entry name" value="ENDONUCLEASE_III_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01155">
        <property type="entry name" value="ENDONUCLEASE_III_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 10" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4 10" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8 10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="12" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="9 10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 10" id="KW-0408">Iron</keyword>
    <keyword evidence="7 10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="10 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="3 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0540">Nuclease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ENDO3c" evidence="11">
        <location>
            <begin position="38"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ40587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="215" mass="24286" checksum="094B7BD4C4305313" modified="2010-01-19" version="1">MNNQKRVQILERLRAENPHPQTELNWSTPFELLIAVLLSAQATDVSVNKAIDKLYPIANTPQAIFDLGVDGLKTYIKTIGLFNTKAENVIKTCRILLDQHNGEVPEDRQALEALPGVGRKTANVVLNTAFGWPTIAVDTHIFRVCNRTKFAEGKNVDQVEQKLLKVVPAEFKVDVHHWLILHGRYTCIARKPRCGSCIIEDLCEYKEKVYPDEGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXD9</accession>
    <name>D0YXD9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ion-translocating oxidoreductase complex subunit C</fullName>
            <ecNumber evidence="4">7.-.-.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Rnf electron transport complex subunit C</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rnfC</name>
        <name evidence="7" type="ORF">VDA_001618</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="4">Binds 2 [4Fe-4S] clusters per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell inner membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="7.-.-.-" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001618"/>
    <dbReference type="EnsemblBacteria" id="EEZ40591">
        <property type="protein sequence ID" value="EEZ40591"/>
        <property type="gene ID" value="VDA_001618"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4656">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00461">
        <property type="entry name" value="RsxC_RnfC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010208">
        <property type="entry name" value="Ion_transpt_RnfC/RsxC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43034">
        <property type="entry name" value="PTHR43034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00037">
        <property type="entry name" value="Fer4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0249">Electron transport</keyword>
    <keyword evidence="2 4" id="KW-0408">Iron</keyword>
    <keyword evidence="3 4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="6">
        <location>
            <begin position="17"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="72"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="136"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="72"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="157"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="327"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="367"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="26"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="29"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="420" mass="45362" checksum="6CC49180C6337267" modified="2010-01-19" version="1">MLPQQLQWYAKDKDYDKCGEYNLSDCIECGACAYVCPSEIPLVQYYRQAKAEIWARKQDEINAERARQRFEAKQARMERDKAERENRFKKAADDRRQEMASTGGNDAVAAAIARVKAKQAAKSEVNEPKPAVAAAIARAKAKQTASAQAGNETPDNSEMAKLREERKRQARERKAAQAENKQTDASTVDEKQSAVAAAVARAKARKAAQQQTQNEKTEVDTHATSTESDPKKAAVAAAVARAKARKAAQQQAQNEKTEVDTHATSTESDPKKAAVAAAVARAKARKAAQQQTQNEKTEVDTHATSTESDPKKAAVAAAVARAKARKAAQQQAQNETTEVDTHTASTESEPKKAAVAAAVARAKARKAAQQQAQNETTEVDTHTASTESDPKKAAVAAAVARAKARKAAQQTAKEQQNEEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXG4</accession>
    <name>D0YXG4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted signal transduction protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001699</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298537.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001699"/>
    <dbReference type="EnsemblBacteria" id="EEZ40670">
        <property type="protein sequence ID" value="EEZ40670"/>
        <property type="gene ID" value="VDA_001699"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1639">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013976">
        <property type="entry name" value="HDOD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08668">
        <property type="entry name" value="HDOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51833">
        <property type="entry name" value="HDOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HDOD" evidence="1">
        <location>
            <begin position="39"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="304" mass="34761" checksum="6F578A45F4DA3485" modified="2010-01-19" version="1">MSHLSFFWLNPEHNKLIKGIESEFCNLVKTSIRNNQLTLPQIPTVLTRLQQACLRKDITVREVANIVIDDPALTAKIIRTSNAVLFNRRNIVCNDLSTAITRLGIMRVRDIATVQAIETLKFSYKKHEQCNKVLQHSAHRSRQLAGTMALICYSINQHPDNAEPLLPEKALLTGLLADIGLFSLLSEYQLYLKNGNYLELDAALFIFQECCSDISPIILKHWGFDNDYQEVASNRKLYSNDNINYLDIARMANHLLLMKNNDDAIHDHYIELDLLGAEVMYELSQLELSELNKQVHDIIKRCGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXK1</accession>
    <name>D0YXK1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001715</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298567.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001715"/>
    <dbReference type="EnsemblBacteria" id="EEZ40686">
        <property type="protein sequence ID" value="EEZ40686"/>
        <property type="gene ID" value="VDA_001715"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2153">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1777515at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004343">
        <property type="term" value="F:glucosamine 6-phosphate N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006048">
        <property type="term" value="P:UDP-N-acetylglucosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039143">
        <property type="entry name" value="GNPNAT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13355">
        <property type="entry name" value="PTHR13355"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13673">
        <property type="entry name" value="Acetyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="139" mass="15439" checksum="37346DBFE6B99D6F" modified="2010-01-19" version="1">MLEIKMVAFDHQYSELIRQVRDDVFIKEQCIDPEIEFDGLDDQAAHVLVVEDGVALGTGRILSDGHIGRIAIIKAARGRGLGAKVVSTLVEFAKQQGYPEVDLGAQTHAIDFYRKLGFLPVGDEFMEANIPHQAMVQKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXN8</accession>
    <name>D0YXN8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glutaredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001737</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298601.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001737"/>
    <dbReference type="EnsemblBacteria" id="EEZ40705">
        <property type="protein sequence ID" value="EEZ40705"/>
        <property type="gene ID" value="VDA_001737"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0695">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2045232at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097573">
        <property type="term" value="F:glutathione oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014025">
        <property type="entry name" value="Glutaredoxin_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00160">
        <property type="entry name" value="GLUTAREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutaredoxin" evidence="1">
        <location>
            <begin position="16"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="102" mass="11492" checksum="3ED3E1A214F0286B" modified="2010-01-19" version="1">MTSLTQEQLAQFSNLVITQPNCPYCVKAKAILDGRGTEYTTLVLGQELAKEEMIEFIEHVANVTVRTVPQIILDGKYIGGHDDLVAFLERQVDTDEFDDFEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXV3</accession>
    <name>D0YXV3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Spermidine putrescine ABC transporter permease component PotC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_002116</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002116"/>
    <dbReference type="EnsemblBacteria" id="EEZ41084">
        <property type="protein sequence ID" value="EEZ41084"/>
        <property type="gene ID" value="VDA_002116"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1177">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="42"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="174"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="4"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="200" mass="21571" checksum="65E70D326CE3DC96" modified="2010-01-19" version="1">MQAAGHSITIAVFSATAAALIGSLTAVALFRYQFKGKKFVTGMLFIVMMSPDIVMAISLLALFLLMGAELGFLTLLLSHITFCLPFVVVTVYSRLKGFDVKMLEAARDLGASEWVILKQIILPLAKPAVAAGWLLSFTLSLDDVIISSFTTGPTYEILPLKIYSMVKVGISPEVNALATIMLVVSLVLVICSQLLAREKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXY6</accession>
    <name>D0YXY6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sigma-54 dependent transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_002149</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299543.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002149"/>
    <dbReference type="EnsemblBacteria" id="EEZ41117">
        <property type="protein sequence ID" value="EEZ41117"/>
        <property type="gene ID" value="VDA_002149"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3829">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="123059at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002197">
        <property type="entry name" value="HTH_Fis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025943">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00158">
        <property type="entry name" value="Sigma54_activat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01590">
        <property type="entry name" value="HTHFIS"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00676">
        <property type="entry name" value="SIGMA54_INTERACT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50045">
        <property type="entry name" value="SIGMA54_INTERACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="5">
        <location>
            <begin position="190"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="500" mass="57115" checksum="436C03984F2FAEBF" modified="2010-01-19" version="1">MKQWLTYTAEMIECRKCSELITFFQNVSVEQLAVAQCLVFYPSDDGRFLISDNGSEQWEVDDFDHPFSHALHHAKPILLDSKKLHFWRQNSDFEYFSQQVSDDESLLVVPLPFQSHRVKAVVGLIGNKQIINNILNDENWLKFSQVFISQWILLRELASKHRQELQLNESITQLKINKTNKGRRDLSHHLIGSSPVMESLREQIAIAAQSSLTVLIQGETGSGKELVAKAIHTLSDRKDKAFVAVNCAAIPENLLESELFGYEKGAFTGAISARKGLIAQADGGTLFLDEMGEMPLALQAKLLRVLETLEYRPLGSHKELRSQFRLVAATHVNLRKNVNQGLFRQDLFYRLYQYPLDVPSLSNRLNDIDELAEVFIDQYNQRENRHVLGFDTQTLTLLKTFEYPGNVRQLRSLVEYACVHTDSNQFINEQALPKTDMSSEKLVSSLPFEEIDDLKLALEEYERKIICDRLTFFAGDRAKAAESLGLPKRTLAHKCQKLEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXZ1</accession>
    <name>D0YXZ1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002154</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299553.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002154"/>
    <dbReference type="EnsemblBacteria" id="EEZ41122">
        <property type="protein sequence ID" value="EEZ41122"/>
        <property type="gene ID" value="VDA_002154"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3520">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1688251at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010732">
        <property type="entry name" value="T6SS_TssG-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35564">
        <property type="entry name" value="PTHR35564"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06996">
        <property type="entry name" value="T6SS_TssG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03347">
        <property type="entry name" value="VI_chp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="335" mass="38158" checksum="933F3E3055FC7C4A" modified="2010-01-19" version="1">MGNSDRVTTADLRSDKRLNTLLDQAKNYDFYQLVELLLKLTEQDPSSEEWESNCRLIFSTSASLGFASSDITELEALSDESYRIETAFLGLNGAQSPLPGFLLEQIATENENGVRRAFLDFFNNRLLALVYQLWRKYRYYVCYQDNASDLFSSQLFALVGLSDSDLRGETPINWSKMLSYAGTLAGRSRSPQVVAGIIAHCFELENVAIRQWEIRTVDIVQEQQMCLGMNNCRLGESTIIGAKVKDCTGKFVVEIKDLTRERFNDFLPSGKEYQPLCKLVEFVLREQMAFDLELELKKEEVPSMCLTRDSQLSLGWSSFLDAKNSDCKVKIQVRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY51</accession>
    <name>D0YY51_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Protein hydE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002214</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002214"/>
    <dbReference type="EnsemblBacteria" id="EEZ41182">
        <property type="protein sequence ID" value="EEZ41182"/>
        <property type="gene ID" value="VDA_002214"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0068">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="399637at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="416" mass="47076" checksum="41209181DD12569D" modified="2010-01-19" version="1">MTLSLDELPPALTANPTRSQVLICNPNTLPQHFIVPEQHVLALSSLEKPRVTVRPNPNQTTLTRALYDIVFGYDRILAIVTERLRQLGVGYVHYQAERYQPLVTWLNEGWSEVQANPNAFSITPVRAVEPLHEDGCFSHINAFWHKGRIHFNHQPVENTVSHEHIATCALLAGGIDHSDSRNSAVIYFGEAGFDEIVTEDKFTRTETFLRQQPMSTFGYDLIAQLEQADQKTILDKFKQQYPEQYQALHQLNLAGFEQKLSGIFAIAATVLGLDGQNVSELNDRLQAQAMSYPNYRGEQIDFDIDPDAEGRSIDWKKMVGSLMSYRLITEEHDIPQLAFGIYDSLVDKLSNWIEHLDQQVGVKSVVLAGKGFTNEVFAWRTALRIGKNYPININRKLDLEGANISAGSLYLKVRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYG5</accession>
    <name>D0YYG5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Cytochrome c-type protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">VDA_002328</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="8">Binds 5 heme groups per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the TorC/TorY family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299883.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002328"/>
    <dbReference type="EnsemblBacteria" id="EEZ41296">
        <property type="protein sequence ID" value="EEZ41296"/>
        <property type="gene ID" value="VDA_002328"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3005">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="738283at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009276">
        <property type="term" value="C:Gram-negative-bacterium-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3820.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009154">
        <property type="entry name" value="Membr-bd_4haem_cyt_TorC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036280">
        <property type="entry name" value="Multihaem_cyt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005126">
        <property type="entry name" value="NapC/NirT_cyt_c_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038266">
        <property type="entry name" value="NapC/NirT_cytc_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03264">
        <property type="entry name" value="Cytochrom_NNT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000014">
        <property type="entry name" value="4_hem_cytch_TorC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48695">
        <property type="entry name" value="SSF48695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02162">
        <property type="entry name" value="torC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="7 8" id="KW-0349">Heme</keyword>
    <keyword evidence="7 9" id="KW-0408">Iron</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrom_NNT" evidence="11">
        <location>
            <begin position="14"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="binding site" description="covalent" evidence="8">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="8">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="8">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="8">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="8">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="8">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>3</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="8">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>4</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="8">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>4</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>4</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="8">
        <location>
            <position position="339"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>5</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="8">
        <location>
            <position position="342"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>5</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="343"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>5</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR000014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000014-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000014-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ41296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="393" mass="44290" checksum="35817AEC627033F7" modified="2010-01-19" version="1">MKTLKKIWQTLWRPATKISLGVLTLGGFIAGVMFWGGFNTGLEMTNTEKFCISCHDMRDTVYPELQQTVHWSNNAGVRATCPDCHVPHNWTDKIARKMQASKEVFGHLFGTIDTKEKFEAKRMELAQHEWERFSANGSKECKHCHKYESMKWDEMSPRAQVQMKQAAARDQSCLDCHKGIAHQLPQNMESSGGMVSELIAQSHSTSFSDGSAYYSVRFLPLYSDESLTTEAGQLEPASEVKVVKVTDKAVEVEIHGWRKTKGFGRVIEQDFGLNIPVAALSKDAAQNDQVVQKGDEKEDDLTGLKWQQVTITLWMQKDNLLPDVQPIWSAAKSAYDTNCSVCHTQPTENHFDANTWPGMFNGMLAFVNLDSDSEAIVLKYLQNHSSTFSKSQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYH1</accession>
    <name>D0YYH1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">2-deoxyglucose-6-phosphate hydrolase YniC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002334</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299899.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002334"/>
    <dbReference type="EnsemblBacteria" id="EEZ41302">
        <property type="protein sequence ID" value="EEZ41302"/>
        <property type="gene ID" value="VDA_002334"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0637">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1167152at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00413">
        <property type="entry name" value="HADHALOGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="217" mass="23683" checksum="57E3459D5F57D89B" modified="2010-01-19" version="1">MLQAAVFDMDGLLVDSEPFWQQAQVEVFTDLGVKISIEDTHKTMGLRIDQVVEFWFNQQPWQGPNCAEVTQTIVDRVKALVREQKPMLPGVVEAITCCKESGLKIALASSSPMDLIEATIDALSLTGLFEAVLSAEHLRYGKPHPEVYINAADALGVKPQHCVAFEDSVNGLLAAKAAQMKGIAVPDAAFSQDPRWAIADCKLSSLHEVNPELLAQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYK6</accession>
    <name>D0YYK6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Phosphoserine aminotransferase</fullName>
            <ecNumber evidence="8">2.6.1.52</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Phosphohydroxythreonine aminotransferase</fullName>
            <shortName evidence="8">PSAT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">serC</name>
        <name evidence="11" type="ORF">VDA_002369</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>2-oxoglutarate + 4-(phosphooxy)-L-threonine = (R)-3-hydroxy-2-oxo-4-phosphooxybutanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:16573"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58452"/>
            <dbReference type="ChEBI" id="CHEBI:58538"/>
            <dbReference type="EC" id="2.6.1.52"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 8 9">
            <text>2-oxoglutarate + O-phospho-L-serine = 3-phosphooxypyruvate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:14329"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:18110"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57524"/>
            <dbReference type="EC" id="2.6.1.52"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
        <text evidence="8">Binds 1 pyridoxal phosphate per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 8 9">Amino-acid biosynthesis; L-serine biosynthesis; L-serine from 3-phospho-D-glycerate: step 2/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8">Cofactor biosynthesis; pyridoxine 5'-phosphate biosynthesis; pyridoxine 5'-phosphate from D-erythrose 4-phosphate: step 3/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 8">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.52" evidence="8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299971.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002369"/>
    <dbReference type="EnsemblBacteria" id="EEZ41337">
        <property type="protein sequence ID" value="EEZ41337"/>
        <property type="gene ID" value="VDA_002369"/>
    </dbReference>
    <dbReference type="GeneID" id="57341431"/>
    <dbReference type="eggNOG" id="COG1932">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="996960at2"/>
    <dbReference type="UniPathway" id="UPA00135">
        <property type="reaction ID" value="UER00197"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00244">
        <property type="reaction ID" value="UER00311"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004648">
        <property type="term" value="F:O-phospho-L-serine:2-oxoglutarate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006564">
        <property type="term" value="P:L-serine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008615">
        <property type="term" value="P:pyridoxine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00611">
        <property type="entry name" value="PSAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00160">
        <property type="entry name" value="SerC_aminotrans_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020578">
        <property type="entry name" value="Aminotrans_V_PyrdxlP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022278">
        <property type="entry name" value="Pser_aminoTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43247">
        <property type="entry name" value="PTHR43247"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000525">
        <property type="entry name" value="SerC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01364">
        <property type="entry name" value="serC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00595">
        <property type="entry name" value="AA_TRANSFER_CLASS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8 9 11" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6 8" id="KW-0664">Pyridoxine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8 9" id="KW-0718">Serine biosynthesis</keyword>
    <keyword evidence="8 9 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_5" evidence="10">
        <location>
            <begin position="4"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="8">
        <location>
            <begin position="76"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="8">
        <location>
            <begin position="237"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="8">
        <location>
            <position position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ41337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="360" mass="39704" checksum="F04B081047B6707A" modified="2010-01-19" version="1">MDKVYNFSAGPAMMPADVIKKAQAELVDWNGLGTSVMEVSHRGKPFLEIAAQSEKDLRDLLSIPDNYHVLFMHGGARGQFAAVPLNLLGDATTADYMDGGFWAHSAVEEASKYCQPNAVDITCERDGKRAILPANQWPLSDDAAFVHFCPNETIDGIEIRDLPVTDKPIIADMSSVILSRQIDVSKYGVIYAGAQKNIGPAGLTIVIVRDDLLGQAKQILPSILDYTVAVDKESMFNTPPTFAWYLAGEVFKWLKSIGGVAEIQKRNEVKAKLLYDAIDHSDFYQNNVHPDNRSAMNVPFQLKNPELDELFLKEADAAGLRALKGHRAVGGMRASIYNAMPYEGVEALVRFMAEFEKKHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYN8</accession>
    <name>D0YYN8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative pseudouridine synthase Rlu family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002401</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002401"/>
    <dbReference type="EnsemblBacteria" id="EEZ41369">
        <property type="protein sequence ID" value="EEZ41369"/>
        <property type="gene ID" value="VDA_002401"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0564">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140098">
        <property type="term" value="F:catalytic activity, acting on RNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034470">
        <property type="term" value="P:ncRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02869">
        <property type="entry name" value="PseudoU_synth_RluA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006508">
        <property type="entry name" value="PsdUridine_synth_RluA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006224">
        <property type="entry name" value="PsdUridine_synth_RluC/D_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01621">
        <property type="entry name" value="RluA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01129">
        <property type="entry name" value="PSI_RLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PseudoU_synth_2" evidence="1">
        <location>
            <begin position="21"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="238" mass="26729" checksum="81371E3426D1198E" modified="2010-01-19" version="1">MRVSFITLRKPMFTLVHEHPDFILIHKHPGVSVHKDDNDQPLLAAVAAQTGDEKLYLIHRLDKMTSGLLLLGRNKEAAAELSGNFANRVVEKFYVAIGSKKPKKKQGIVIGDMTRSRRSSWKLESSKHNPAITQFFSTAAGNGRRLFLCKPHTGKTHQIRVALKSVGSGITGDDIYGNEAADRGYLHAYALSFPYQGEQYRFLCVPTFGQLWQEADTVAGLEQWQQPWLLDWPKIGSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYT5</accession>
    <name>D0YYT5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002448</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300111.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002448"/>
    <dbReference type="EnsemblBacteria" id="EEZ41416">
        <property type="protein sequence ID" value="EEZ41416"/>
        <property type="gene ID" value="VDA_002448"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1801">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1068600at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002763">
        <property type="entry name" value="DUF72"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036520">
        <property type="entry name" value="UPF0759_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30348">
        <property type="entry name" value="PTHR30348"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01904">
        <property type="entry name" value="DUF72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117396">
        <property type="entry name" value="SSF117396"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="298" mass="34040" checksum="87BF9311ABCF9F0B" modified="2010-01-19" version="1">MQPNSSPPLRLGLAMWSHNQWQQSIYGKGCKTGDRLARYAETFNTVEGNTTFYAVPNLTTTQKWHSATPDNFRFTFKLPKTITHQQQLRHSQQSLSDFFSVMSPLEHKIGLWKIQLPASFGPESLPLLKQFLDLFPSHYPVGVEVRHAAFFAKGEDERRFNHLLFEKKANRIIMDSRPVFAAPPTSAAVKDAHQKKPRVPVHAIATADNPMIRFIGHPDDLSNDPFFANWLTRLPIWLNEGKQPYLFIHTPDNNHAPELATRLYALLKQQSIKQLSTVNLPSITLPILNDENPQFNLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYY5</accession>
    <name>D0YYY5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Succinate--CoA ligase [ADP-forming] subunit alpha</fullName>
            <ecNumber evidence="2">6.2.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Succinyl-CoA synthetase subunit alpha</fullName>
            <shortName evidence="2">SCS-alpha</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">sucD</name>
        <name evidence="7" type="ORF">VDA_002498</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 5">Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 5">
            <text>ATP + CoA + succinate = ADP + phosphate + succinyl-CoA</text>
            <dbReference type="Rhea" id="RHEA:17661"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.2.1.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Carbohydrate metabolism; tricarboxylic acid cycle; succinate from succinyl-CoA (ligase route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 5">Heterotetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the succinate/malate CoA ligase alpha subunit family.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.5" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300203.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002498"/>
    <dbReference type="EnsemblBacteria" id="EEZ41466">
        <property type="protein sequence ID" value="EEZ41466"/>
        <property type="gene ID" value="VDA_002498"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0074">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1081709at2"/>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER00999"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004775">
        <property type="term" value="F:succinate-CoA ligase (ADP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.261">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01988">
        <property type="entry name" value="Succ_CoA_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017440">
        <property type="entry name" value="Cit_synth/succinyl-CoA_lig_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033847">
        <property type="entry name" value="Citrt_syn/SCS-alpha_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003781">
        <property type="entry name" value="CoA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005810">
        <property type="entry name" value="CoA_lig_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005811">
        <property type="entry name" value="CoA_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02629">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00549">
        <property type="entry name" value="Ligase_CoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001553">
        <property type="entry name" value="SucCS_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00881">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52210">
        <property type="entry name" value="SSF52210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01019">
        <property type="entry name" value="sucCoAalpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01216">
        <property type="entry name" value="SUCCINYL_COA_LIG_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00399">
        <property type="entry name" value="SUCCINYL_COA_LIG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="1 2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="CoA_binding" evidence="6">
        <location>
            <begin position="4"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Coenzyme A binding" evidence="2">
        <location>
            <begin position="17"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Coenzyme A binding" evidence="2">
        <location>
            <begin position="96"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="2 3">
        <location>
            <position position="247"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared with subunit beta</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001553-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="290" mass="29831" checksum="5890B20DE32B1964" modified="2010-01-19" version="1">MSILINKDTKVICQGFTGGQGTFHSEQAIAYGTQMVGGVSPGKGGSTHLGLPVFNTVREAVEATGATATVIYVPAPFCKDAILEAIDAGIELIVTITEGIPTLDMLDVKVRLDQAGVRMIGPNCPGVITPDECKIGIMPGHIHKAGNVGIVSRSGTLTYEAVKQTTDEGFGQSTCVGIGGDPIPGSSFIDILAMFEQDPATDAIVMIGEIGGTAEEDAAAYIKQHVTKPVVSYIAGVTAPPGKRMGHAGAIISGGKGTAEDKFAALEAAGVRTVKSLADIGLVLREVMPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ26</accession>
    <name>D0YZ26_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cobalt-zinc-cadmium resistance protein czcA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_002539</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300284.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002539"/>
    <dbReference type="EnsemblBacteria" id="EEZ41507">
        <property type="protein sequence ID" value="EEZ41507"/>
        <property type="gene ID" value="VDA_002539"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3696">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="91817at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004763">
        <property type="entry name" value="CzcA/CusA/SilA/NccA/HelA/CnrA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00914">
        <property type="entry name" value="2A0601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="338"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="364"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="390"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="439"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="479"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="531"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="865"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="891"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="917"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="976"/>
            <end position="995"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="1007"/>
            <end position="1030"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="1041" mass="113980" checksum="F09EC24A3AF9F5A5" modified="2010-01-19" version="1">MIPAIIRWSIKNRFLVLMATVFLVAAGIYSVKRTPIDALPDLSDVQVIIKTSYPGQAPQVVEDQVTYPLTTAMLAVPGAETVRGYSFFGDSYVYIIFNDDTDMYWARSRVLEYLSQVAPKLPPSAKPVLGPDATGVGWIYSYVLTDRSGKHDLSELRSLQDWFLKYELQTVDGVSEIATVGGMVKQYQIQIDPNKLRAYNLTLQQINKAIKAGNQEAGASVVEVAEAEHMVRATGYIKNIADLKNIPLGVTSKGTPLLLGDVADINLGPQMRRGISEFNGEGEAVGGVVVMRFGENAQQVIANVKEKLASLQRSLPEGVEIVPTYDRSTLIDNAVDNLYQKLLEEFIVVAIVCALFLFHLRSSLVVMISLPIGILSAFIVMHWQGINANIMSLGGIAIAIGAMVDGAIVMIENVHKHIEKTPLTDENRWQVIGKAAEEVGAPLFFSLLIITLSFVPVFALEGQEGKMFSPLAFTKTYAMASAAGLAITLVPVLMGYFIRGKVLPEHKNPINKAVVSAYRPLLNISLRHPKSLLVAAGILMASAYYPIHNMGSEFIPPLDEGDLMYMPTTYPGISIGKAREILQQTDKLIKTIPEVKTVWGKIGRAETATDPAPLTMIETIIQLKPRDEWRPGVTTASLRHELDQLVQFPGLTNAWIMPIKTRIDMLATGIKTPIGVKIAGPALKQIEKIGQQLETILKPVPGTASVYAERVAGGRYITMDIDRQKAARYGLNIQDIQQVITTAIGGMNVSETIEGLERYPINVRYPQSYRDSLEKLKSLPLVTPSGARIALADVATLRFEDGPPMIKTENARPNGWVFVDIDGRDLGSYVHEAQQKVAQELVLPAGYSLSWSGQYEYMERAKARLTTVVPATIAIIMMLLYMSFRRAGEVLLIMGTLPLAMVGGLWLMEILDYNFSIAVGVGFIALAGVAVEIGVIMLVYLNQAWNGQIEQAKQEQRALTMADLTKAISEGAGLRVRPVMMTVATVIIGLIPIMFGHGTGSEVMQRIAAPMIGGMSSALLLTLVVLPALFKLWKQTSYKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ37</accession>
    <name>D0YZ37_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Multidrug resistance protein B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002550</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300304.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002550"/>
    <dbReference type="EnsemblBacteria" id="EEZ41518">
        <property type="protein sequence ID" value="EEZ41518"/>
        <property type="gene ID" value="VDA_002550"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1108236at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="162"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="196"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="226"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="265"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="303"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="332"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="362"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="396"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="481"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="511" mass="56466" checksum="9A134B32B28CD5F2" modified="2010-01-19" version="1">MFRYVGLIICIVFTFVPFGLNSEMFSDAASEMAVSIGASADELSVIKIIFMAAQIAGLVLTPRLVRMKGVTVSLTAAVCCALLVNIGLYVSHTIIMSSMLWAINGFVLSVILISVNLLILDTCPRKQLPIFIAGALVFTTLLPMGMYSWLMAEILEHFSWQMFIVFQIWSYAIALIWLVVYPPSNRIFVAEPKSNHFIYLLSLSFFSLVTYLLMRGSYYNWLDNPIYLDLVILSGVLALAIILFIMQRKQKTITQQVLSKLNTNVYMYNAFLAGFAVMSSNVLCDSFLEKALHYNALVTGETKLPAVITMLLGMAVSVWVSNHKPALSDKIVPIGVLLILISSIKLSFMPSYVCPEQLTIPLLLRGFGIGLLNVSVSIAVLMYFTREEQLEGVSCFYLFRTVGGLIGGAFFSHFIHIESAQAINQVNSNVTAFSNTVTHYQATLNNTFLINGHLPSQAMGANYMSGVVQQQVMTLTLNNSLIMFVIAICILAPILIVGKKMAAKQKEAAEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ81</accession>
    <name>D0YZ81_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Flagellar motor switch protein FliN</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">VDA_002594</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Peripheral membrane protein</topology>
            <orientation evidence="8">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Bacterial flagellum basal body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the FliN/MopA/SpaO family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300423.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002594"/>
    <dbReference type="EnsemblBacteria" id="EEZ41562">
        <property type="protein sequence ID" value="EEZ41562"/>
        <property type="gene ID" value="VDA_002594"/>
    </dbReference>
    <dbReference type="GeneID" id="57341162"/>
    <dbReference type="eggNOG" id="COG1886">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1875967at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003774">
        <property type="term" value="F:cytoskeletal motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012826">
        <property type="entry name" value="FliN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001543">
        <property type="entry name" value="FliN-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001172">
        <property type="entry name" value="FliN_T3SS_HrcQb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036429">
        <property type="entry name" value="SpoA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01052">
        <property type="entry name" value="FliMN_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00956">
        <property type="entry name" value="FLGMOTORFLIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101801">
        <property type="entry name" value="SSF101801"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02480">
        <property type="entry name" value="fliN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="4 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0966">Cell projection</keyword>
    <keyword evidence="5 8" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="11" id="KW-0969">Cilium</keyword>
    <keyword evidence="6 8" id="KW-0283">Flagellar rotation</keyword>
    <keyword evidence="11" id="KW-0282">Flagellum</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FliMN_C" evidence="10">
        <location>
            <begin position="48"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="19"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ41562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="128" mass="14138" checksum="690F6840785D4C55" modified="2010-01-19" version="1">MSQNDQQMADEWAAALAEQEAQVQPAPLEELTDDSAPVSDDERRKLDSILDIPVTISMEVGRTQISIRNLLQLNQGSVVELDRVAGESLDVMVNGTLIAHGEVVVVNDKFGIRLTDVISQTERIKKLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-06-02" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ89</accession>
    <name>D0YZ89_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_002602</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002602"/>
    <dbReference type="EnsemblBacteria" id="EEZ41570">
        <property type="protein sequence ID" value="EEZ41570"/>
        <property type="gene ID" value="VDA_002602"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4191">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13188">
        <property type="entry name" value="PAS_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6" id="KW-0969">Cilium</keyword>
    <keyword evidence="6" id="KW-0282">Flagellum</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="5">
        <location>
            <begin position="148"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="360" mass="39712" checksum="4C028A818A4B3208" modified="2010-01-19" version="1">MKNICFIWHVFCLIRLLSIFVFFMDELKTSLSLSQQARYQQVFDVMPTGVLLLDATGRIHDANPEAHRLLDEPLIGERWIDIIKRAFAPQDDDGHEVSLHNGRKVKLAISASSEGQLIFITDMTETRLLQSRLSELQRLSSLGKMVASLAHQVRTPLSSAMLYASHLGSEQLAPATRQRFQGKLVDRLHDLEKQVSDMLLFAKGGDNKVVTRFSLESLLNCLEAMIEQPVIHHQIDFSIDCDDESCCLLGNENALASAISNLVINAIQNAGDGAQIAIQCQLQQGNILISVADNGPGIPAELQHKILEPFFTTRSQGTGLGLAVVQMVVHAHNGQLNIVSEPEQGACFTLQLPLADTDTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZB8</accession>
    <name>D0YZB8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">DNA ligase</fullName>
            <ecNumber evidence="10">6.5.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Polydeoxyribonucleotide synthase [NAD(+)]</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ligA</name>
        <name evidence="12" type="ORF">VDA_002631</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="10">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the NAD-dependent DNA ligase family. LigA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.5.1.2" evidence="10"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002631"/>
    <dbReference type="EnsemblBacteria" id="EEZ41599">
        <property type="protein sequence ID" value="EEZ41599"/>
        <property type="gene ID" value="VDA_002631"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0272">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003911">
        <property type="term" value="F:DNA ligase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01588">
        <property type="entry name" value="DNA_ligase_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041663">
        <property type="entry name" value="DisA/LigA_HHH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033136">
        <property type="entry name" value="DNA_ligase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001679">
        <property type="entry name" value="DNAligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013839">
        <property type="entry name" value="DNAligase_adenylation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013840">
        <property type="entry name" value="DNAligase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003583">
        <property type="entry name" value="Hlx-hairpin-Hlx_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004150">
        <property type="entry name" value="NAD_DNA_ligase_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004149">
        <property type="entry name" value="Znf_DNAligase_C4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01653">
        <property type="entry name" value="DNA_ligase_aden"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03120">
        <property type="entry name" value="DNA_ligase_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03119">
        <property type="entry name" value="DNA_ligase_ZBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12826">
        <property type="entry name" value="HHH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00278">
        <property type="entry name" value="HhH1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00532">
        <property type="entry name" value="LIGANc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="SSF52113"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00575">
        <property type="entry name" value="dnlj"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01056">
        <property type="entry name" value="DNA_LIGASE_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9 10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3 10" id="KW-0235">DNA replication</keyword>
    <keyword evidence="2 10 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="7 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0464">Manganese</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 10" id="KW-0520">NAD</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="BRCT" evidence="11">
        <location>
            <begin position="417"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="active site" description="N6-AMP-lysine intermediate" evidence="10">
        <location>
            <position position="4"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="257"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ41599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="495" mass="54437" checksum="0B1EF3716043DBC3" modified="2010-01-19" version="1">MPKKGFEQLNQRALKKGEKTFANPRNAAAGSLRQLDSKVTATRPLSFYAYAVGIVEGRELEGSQYDRLCQLKSWGFPMSPEIRRVDSIEEVIRYHQMIGEKRESLEYDIDGVVIKVDKVDTQLQLGFVARAPRWAIAYKFPAQEEMTLLNNVEFQVGRTGAITPVAKLEPVFVGGVTVSNATLHNADEIARLGVMVGDTVIIRRAGDVIPQIVSVVESRRPADASPVIFPTECPVCQSKVERIEGEAVARCTGGLFCQAQRKEALKHFVSRKALDVDGCGEKVIEQLVDREMVTTPADLFRLSAGVVTALDRMGPKSAQKLVDALGNAKETTLSRFIYSLGIREVGEATAANLAHYFETLEALMTASKDQLIEVPDVGEIVAAHIFNFFREEHNLAVVNDLRDVGIHWPDIEKVADDVELPFEGKTVVLTGSLSQLSRTEAKEALQKLGAKVTGSVSKKTDLVVAGEAAGSKLTKAQELGIEVWDEQQLIDFMQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZC8</accession>
    <name>D0YZC8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Periplasmic nitrate reductase, electron transfer subunit</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Diheme cytochrome c NapB</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_002641</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NapB family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002641"/>
    <dbReference type="EnsemblBacteria" id="EEZ41609">
        <property type="protein sequence ID" value="EEZ41609"/>
        <property type="gene ID" value="VDA_002641"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3043">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009061">
        <property type="term" value="P:anaerobic respiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036280">
        <property type="entry name" value="Multihaem_cyt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005591">
        <property type="entry name" value="NapB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03892">
        <property type="entry name" value="NapB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48695">
        <property type="entry name" value="SSF48695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ41609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="39" mass="4460" checksum="08C2B2E0AA313E33" modified="2010-01-19" version="1">MSDVSPSRYFCQQCHVPQVDAKPLVGNQFKRVEALQESH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZD8</accession>
    <name>D0YZD8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Xanthine/uracil/thiamine/ascorbate permease family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_002651</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300605.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002651"/>
    <dbReference type="EnsemblBacteria" id="EEZ41619">
        <property type="protein sequence ID" value="EEZ41619"/>
        <property type="gene ID" value="VDA_002651"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2252">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="558559at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015205">
        <property type="term" value="F:nucleobase transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904823">
        <property type="term" value="P:purine nucleobase transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045018">
        <property type="entry name" value="Azg-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026033">
        <property type="entry name" value="Azg-like_bact_archaea"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006043">
        <property type="entry name" value="NCS2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43337">
        <property type="entry name" value="PTHR43337"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00860">
        <property type="entry name" value="Xan_ur_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005353">
        <property type="entry name" value="PbuG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="49"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="94"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="168"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="193"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="238"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="318"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="343"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="374"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="411"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ41619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="429" mass="44867" checksum="73302443A4BFCA74" modified="2010-01-19" version="1">MFEKLFKLKENGTNVRTEVLAGVTTFLTMAYIIFVNPTMLANTGMDKGAVFVATCLAAMIGCFVMGFIANYPVAQAPGMGLNAFFTYSVVLGMGYTWQVALAAVFLSGLCFIALSLLKVREWIINAIPHSLRIGISAGIGLFLAFIALQSSGIVVDNPATLVSAGDLTSFPAVMAALGFFLTIALVHRGYKAAVLIAILVVTGISIIFGEVTYNGVVSMPPSLAPTFMQLDFSGAMEVGLISVVFAFLFVDLFDTAGTLVGVATKANLMDKDGKLPRLSRALLADSTATSVGALLGTSNTTSFVESVSGVAVGGRTGLTAVTVGVLFLLALFFAPLAGMVPAYATAGALFYVAILMISGLVSVDWRDLTEAAPVVVVCLLMPLTYSIAEGIGLGFITYAAVKVMSGKGRDINVSVWVIAGLFLAKIIFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZH1</accession>
    <name>D0YZH1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Nitrogen regulatory protein P-II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_002684</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the P(II) protein family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300696.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002684"/>
    <dbReference type="EnsemblBacteria" id="EEZ41652">
        <property type="protein sequence ID" value="EEZ41652"/>
        <property type="gene ID" value="VDA_002684"/>
    </dbReference>
    <dbReference type="GeneID" id="57341047"/>
    <dbReference type="eggNOG" id="COG0347">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2021322at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030234">
        <property type="term" value="F:enzyme regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006808">
        <property type="term" value="P:regulation of nitrogen utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002187">
        <property type="entry name" value="N-reg_PII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017918">
        <property type="entry name" value="N-reg_PII_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002332">
        <property type="entry name" value="N-reg_PII_urydylation_site"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30115">
        <property type="entry name" value="PTHR30115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00543">
        <property type="entry name" value="P-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039144">
        <property type="entry name" value="GlnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00340">
        <property type="entry name" value="PIIGLNB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00938">
        <property type="entry name" value="P-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="SSF54913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00638">
        <property type="entry name" value="PII_GLNB_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51343">
        <property type="entry name" value="PII_GLNB_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00496">
        <property type="entry name" value="PII_GLNB_UMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="O-UMP-tyrosine" evidence="2">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR039144-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR602187-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="112" mass="12519" checksum="F0509F65977B1C5B" modified="2010-01-19" version="1">MKKIEAIIKPFKLDDVREALADVGITGMTVTEVKGFGRQKGHTELYRGAEYMVDFLPKVKLEIVVADEVAEQCIDTIVETAQTGKIGDGKIFMFDVERVVRIRTGEEDEDAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZN3</accession>
    <name>D0YZN3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002746</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300896.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002746"/>
    <dbReference type="EnsemblBacteria" id="EEZ41714">
        <property type="protein sequence ID" value="EEZ41714"/>
        <property type="gene ID" value="VDA_002746"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0826">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1264653at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001539">
        <property type="entry name" value="Peptidase_U32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032525">
        <property type="entry name" value="Peptidase_U32_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01136">
        <property type="entry name" value="Peptidase_U32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16325">
        <property type="entry name" value="Peptidase_U32_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01276">
        <property type="entry name" value="PEPTIDASE_U32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_U32_C" evidence="1">
        <location>
            <begin position="359"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="458" mass="51908" checksum="108DFDA33663F097" modified="2010-01-19" version="1">MFTPELLSPAGSLKNMRYAFAYGADAVYAGQPRYSLRVRNNEFNHENLKIGIDEAHALGKKFYVVCNIQPHNSKLKTFIRDLKPIVDMGPDALIMSDPGLIMMVREAFPEMTIHLSVQANAVNWATVKFWETQGVERVILSRELSLEEIEEIREQCPKMELEVFVHGALCMAYSGRCLLSGYINKRDPNQGTCTNACRWEYKTEKATENDAGQIVEVQEAVQIERPDNTIGLGKPTDEVVLLSESHRPEEKMAAFEDEHGTYIMNSKDLRAIQHVERLTKMGVHSLKIEGRTKSFYYCARTAQVYRQAIDDAVAGKPFDPTLMTTLESLAHRGYTEGFLRRHTHDAYQNYEYGYSISDTQQFVGEFTGKRRGDLAEIEVKNKFVVGDSLEVMTPKGNVIFTLERMENRKSEAVDDAKGNGHFVFIPVPEDMDLSYGLLMRNLNSGENTRNPHAPKDGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZN6</accession>
    <name>D0YZN6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Formate dehydrogenase N alpha subunit</fullName>
            <ecNumber evidence="13">1.2.1.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">VDA_002749</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
            <dbReference type="ChEBI" id="CHEBI:60539"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.2" evidence="13"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002749"/>
    <dbReference type="eggNOG" id="COG0243">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3383">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047111">
        <property type="term" value="F:formate dehydrogenase (cytochrome-c-553) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008863">
        <property type="term" value="F:formate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043546">
        <property type="term" value="F:molybdopterin cofactor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045333">
        <property type="term" value="P:cellular respiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006443">
        <property type="entry name" value="Formate-DH-alph_fdnG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006657">
        <property type="entry name" value="MoPterin_dinucl-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006656">
        <property type="entry name" value="Mopterin_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006963">
        <property type="entry name" value="Mopterin_OxRdtase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006655">
        <property type="entry name" value="Mopterin_OxRdtase_prok_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04879">
        <property type="entry name" value="Molybdop_Fe4S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00384">
        <property type="entry name" value="Molybdopterin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01568">
        <property type="entry name" value="Molydop_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00926">
        <property type="entry name" value="Molybdop_Fe4S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="SSF50692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01553">
        <property type="entry name" value="formate-DH-alph"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51669">
        <property type="entry name" value="4FE4S_MOW_BIS_MGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00932">
        <property type="entry name" value="MOLYBDOPTERIN_PROK_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="9 11" id="KW-0408">Iron</keyword>
    <keyword evidence="10 11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="8 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-0574">Periplasm</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0711">Selenium</keyword>
    <keyword evidence="7 13" id="KW-0712">Selenocysteine</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="domain" description="4Fe-4S Mo/W bis-MGD-type" evidence="12">
        <location>
            <begin position="43"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="non-standard amino acid" description="Selenocysteine" evidence="13">
        <location>
            <position position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ41717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="1004" mass="111704" checksum="679A94B8D924F972" modified="2010-01-19" version="1">MNISRRQLFKLCAGTVVASTITSLATISKKAWAEAREFKLTAAKETRNTCSYCSVGCGTLLYSTGAANGNIKQKIFHVEGDPDHPVSRGALCPKGAGLSGFVNSEQRLKFPEYRAPGSDKWQRISWDEAFTRIAKLMKADRDANFIEKNDQGTTVNRWLSTGMLCASAESNENGWLTQKFARGLGMVPVDTQARIUHGPTVASLAPTFGRGAMTNNWVDIKNANVILVMGGNAAEAHPVGFRWVVEAQKHNNAELIVVDPRFTRTAAVADHYVPIRSGADIAFLLGAIRYMMETGQVNHEYVKAYTNASFIVRDDYEFHDGLFSGYDAKERKYDRSSWFYKLDDQGYALKDETLNHPRCVWNLLKDHVSRYTPEVVSNITGTPVEQYNMVCKALASTAADNRTATILYATGWTQHSKGAENIRCMAMIQLLLGNMGMAGGGVNALRGHSNIQGITDLGLLAQSLPGYLKLPSDKDVDFQTHLKHHTPTALEPGQTNYWQHYPAFFTSLLKSFYGKNATAENNFGYDMMPKWDQMYDMLRYFDMMYKGKVNGYICQGFNPVASMSNKQKTLDALSNLKYLITIDPLVTETSTFWQNKPNVNEVDTANIQTEVFRLPCACFAEEDGTIVSSARWLQWHWKAGDMPGEAKGDAEILAGIFLKMREMYQKEGGTYADPILSLDWSYAIPSEPNVRELAKELNGKDANGNQLSSFAQLKADGSTTSGCWLYTGSWTEAGCQTSRRDNHDPSGLGLAPNWAWAWPLNRRVLYNRASTRPDGTPWDKSRTLVEWNGSKWVGPDVPDFNAKLPPSSNAGPFIMQPEGVGRLFALDKMAEGPFPEHYEPFETPIGTNPLHKNVVSNPAARLFKDDAAQLGTKVDFPFVATTYRLTEHFHTWTSHSQYNAVLQPEQFVEIGEGLAKEKGINNADMIRVTSKRGFIEAKAYVSKRITPLHVNGQIVHTVGIPIHWGYEGDTKPGYLANTLSPCVGDANSQTPEYKAFLVNVEKVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZV4</accession>
    <name>D0YZV4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Agglutination protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_002817</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002817"/>
    <dbReference type="EnsemblBacteria" id="EEZ41785">
        <property type="protein sequence ID" value="EEZ41785"/>
        <property type="gene ID" value="VDA_002817"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1538">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019867">
        <property type="term" value="C:outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010130">
        <property type="entry name" value="T1SS_OMP_TolC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01844">
        <property type="entry name" value="type_I_sec_TolC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="169"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="468" mass="51753" checksum="3AA3FE1C51B8C34B" modified="2010-01-19" version="1">MTNGVHDLAIKKHKLGRMTAKQLLALAVSSALFAPVVNSQTLEQTVAYTIETSPVITQSFNQFKAREEQVNQAMSGYLPTLDLTAGYGLEKNETPVSKAAKKGDIELDRSELGLSLRQNLFNGFFTTHDVDRLDHETSAAQWQLFATAEDMALQVAKVYLNYLEASQIVALAQENVNKHQALYGQIEEKTRSGLGSTADLSQSKGRLARAKSNLVAAQNNLADAKSEYAKITKQAPINMTKPAADRAALPQTLEQALTLAKDNHPVLQAAYSDIQAAESEKDATQANYYPDIDLELSGLWSNESYDRSSPNDGDSQELKAGIQMRYNLFNGGKDTAREREAAYKIGEAKGIQQNTYRSIVDGTTLAWNAYQYLGEQKTFIQEHVAASKETQSSYAQQFKLGQRSLLDLLDSENELFEAKKDYLGAEFDELLAQYRLLNATGQLLSSLQITTPETWYGEQEYISGVQGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZX0</accession>
    <name>D0YZX0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9 10">Translation initiation factor IF-2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">infB</name>
        <name evidence="13" type="ORF">VDA_002833</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 10">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301145.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002833"/>
    <dbReference type="EnsemblBacteria" id="EEZ41801">
        <property type="protein sequence ID" value="EEZ41801"/>
        <property type="gene ID" value="VDA_002833"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0532">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="347113at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03702">
        <property type="entry name" value="IF2_mtIF2_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00100_B">
        <property type="entry name" value="IF_2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013575">
        <property type="entry name" value="IF2_assoc_dom_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044145">
        <property type="entry name" value="IF2_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006847">
        <property type="entry name" value="IF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000178">
        <property type="entry name" value="TF_IF2_bacterial-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015760">
        <property type="entry name" value="TIF_IF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023115">
        <property type="entry name" value="TIF_IF2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036925">
        <property type="entry name" value="TIF_IF2_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43381">
        <property type="entry name" value="PTHR43381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11987">
        <property type="entry name" value="IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08364">
        <property type="entry name" value="IF2_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04760">
        <property type="entry name" value="IF2_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52156">
        <property type="entry name" value="SSF52156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00487">
        <property type="entry name" value="IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01176">
        <property type="entry name" value="IF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5 9 10" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="6 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="12">
        <location>
            <begin position="433"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="50"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="G-domain" evidence="9">
        <location>
            <begin position="436"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="62"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="88"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="127"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="442"/>
            <end position="449"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="488"/>
            <end position="492"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="542"/>
            <end position="545"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ41801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="934" mass="102258" checksum="0E082C753109C0D2" modified="2010-01-19" version="1">MSEVTVKTLADEIGTPIDRLLQQLSDAGIAKKADDNVSQTEKQTLLSHLQKEHGGNVSADGAPTRLTLQRKTRSTLSVSGSGGKNKSVQVEVRKKRTYVKRSALEEEQRAAEEAAKNAVNEAAQREAEAIAQRDAEEAAKREAQEQANRAAEEKRLAEEQAKREAEEKAKRDADDAQRLAEEQAKREAGEQAKRTEEEKRKAEEKAKRAVADEQAKKEAEALQRRREEEAKRKAEEESQRQLEEARKMAEQNEKNWAEKNTSGLEMEKSDYHTTTSTYARAAEDEQDRREEGNRRKKKKPSAKQQQQQEDRNGGNNRRGGRNQRGGRGKGQMAKPTSMQHGFDKTAVVAKQDVVIGETIVVSELANKMSVKGVEVIKVMMKMGAMATINQVIDQETAALVAEEMGHKVILRKENELEEAVLSDRNADDLAKVSRAPVVTIMGHVDHGKTSTLDYIRKAHVAAGEAGGITQHIGAYHVQTDNGMITFLDTPGHAAFTAMRARGAQATDIVVLVVAADDGVMPQTIEAIQHAKAAGVPLIIAVNKIDKEGANPDNVKNELAQYDVIPEEWGGENIFVHISAKQGTNIDGLLEAILLQAEVLELTAIEDGMAKGVVVESRLDKGRGPVATVLVQEGTLHKGDIVLCGLEYGRVRAMRDELGQEIESAGPSIPVEILGLSGVPASGDEATVVRDERKAREVALYRQGKFRDVKLARQQKAKLENMFSNMAAGEVAELNVVLKADVQGSVEAIADSLRKLSTDEVKVNIVGSGVGGITETDAVLAAASNAIILGFNVRADASARKTIEAENLDLRYYSIIYQLIDEVKAAMGGMLSPEFKQEIIGLAEVRDVFKSPKLGAIAGCMVTEGTIKRSNPIRVLRDNVVIYEGELESLRRFKDDVNEVKNGYECGIGVKNYNDVRVGDQIEVYEIVEIQRTLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZY2</accession>
    <name>D0YZY2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Carbamoyl-phosphate synthase large chain</fullName>
            <ecNumber evidence="13">6.3.5.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Carbamoyl-phosphate synthetase ammonia chain</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">carB</name>
        <name evidence="17" type="ORF">VDA_002845</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>2 ATP + H2O + hydrogencarbonate + L-glutamine = 2 ADP + carbamoyl phosphate + 2 H(+) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:18633"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="13">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="13">Binds 4 Mg(2+) or Mn(2+) ions per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="13">Amino-acid biosynthesis; L-arginine biosynthesis; carbamoyl phosphate from bicarbonate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 13">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 1/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the CarB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.5" evidence="13"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301178.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002845"/>
    <dbReference type="EnsemblBacteria" id="EEZ41813">
        <property type="protein sequence ID" value="EEZ41813"/>
        <property type="gene ID" value="VDA_002845"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0458">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="48855at2"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00171"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004088">
        <property type="term" value="F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01424">
        <property type="entry name" value="MGS_CPS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1030.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01210_A">
        <property type="entry name" value="CPSase_L_chain_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01210_B">
        <property type="entry name" value="CPSase_L_chain_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006275">
        <property type="entry name" value="CarbamoylP_synth_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005480">
        <property type="entry name" value="CarbamoylP_synth_lsu_oligo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036897">
        <property type="entry name" value="CarbamoylP_synth_lsu_oligo_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CbamoylP_synth_lsu-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005483">
        <property type="entry name" value="CbamoylP_synth_lsu_CPSase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011607">
        <property type="entry name" value="MGS-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036914">
        <property type="entry name" value="MGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033937">
        <property type="entry name" value="MGS_CPS_CarB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02787">
        <property type="entry name" value="CPSase_L_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02142">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00098">
        <property type="entry name" value="CPSASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01096">
        <property type="entry name" value="CPSase_L_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00851">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48108">
        <property type="entry name" value="SSF48108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52335">
        <property type="entry name" value="SSF52335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01369">
        <property type="entry name" value="CPSaseII_lrg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00866">
        <property type="entry name" value="CPSASE_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51855">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="13" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="9 13 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 13 17" id="KW-0436">Ligase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12" id="KW-0464">Manganese</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 13 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11 13" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 13" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ATP-grasp" evidence="15">
        <location>
            <begin position="133"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="15">
        <location>
            <begin position="678"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="domain" description="MGS-like" evidence="16">
        <location>
            <begin position="936"/>
            <end position="1074"/>
        </location>
    </feature>
    <feature type="region of interest" description="Carboxyphosphate synthetic domain" evidence="13">
        <location>
            <begin position="1"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Oligomerization domain" evidence="13">
        <location>
            <begin position="404"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Allosteric domain" evidence="13">
        <location>
            <begin position="936"/>
            <end position="1074"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="285"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="299"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="301"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="828"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="840"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="842"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>4</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EEZ41813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="1074" mass="117790" checksum="7D5EB2FB835E3D7A" modified="2010-01-19" version="1">MPKRTDIKSVLILGAGPIVIGQACEFDYSGAQACKALREEGYRVILVNSNPATIMTDPNMADATYIEPIHWEVVRKIIEKERPDAVLPTMGGQTALNCALDLERHGVLAEFGVEMIGATADAIDKAEDRSRFDAAMKSIGLECPRADTAKTMEEAYRVLDMVGFPCIIRPSFTMGGTGGGIAYNKEEFEEICRRGLDLSPTNELLIDESLIGWKEYEMEVVRDKNDNCIIVCAIENFDPMGIHTGDSITVAPAQTLTDKEYQLMRNASLAVLREIGVETGGSNVQFGINPKDGRMVIIEMNPRVSRSSALASKATGFPIAKVAAKLAIGYTLDELMNDITGGATPASFEPTIDYVVTKIPRFNFEKFAGANDRLTTQMKSVGEVMAIGRNQQESLQKALRGLEVGAAGFDEMVDLDAPDALTKIRHELKDAGAERIWYIADAFRAGMSVDGVFNLTNIDRWFLVQIEEIVRLEEQVKAAGFAGLNADALRKLKRKGFADARLAKLLGVAESEIRKLRDQYNIHPVYKRVDTCAAEFSSDTAYMYSSYDEECEANPTDREKIMVLGGGPNRIGQGIEFDYCCVHASLALREDGYETIMVNCNPETVSTDYDTSDRLYFEPVTLEDVLAIARVEKPKGVIVQYGGQTPLKLARALEAAGVPIIGTSPDAIDRAEDRERFQQAVERLGLLQPENATVTTIEQAIEKSREIGYPLVVRPSYVLGGRAMEIVYDETDLRRYFNEAVSVSNESPVLLDRFLDDATEVDVDAICDGERVVIGGIMEHIEQAGVHSGDSACSLPAYTLSQEIQDVMRDQVEKLAFELGVRGLMNTQFAVKNNQVYLIEVNPRAARTVPFVSKATGAPLAKIAARVMAGQSLESQGFTKEIIPPYYSVKEVVLPFNKFPGVDPLLGPEMRSTGEVMGIGNTFAEAFAKAELGCGKEYPEGGRALLSVREGDKQRVVDLASKLIKLGYQLDATHGTAVILGEAGINPRLVNKVHEGRPHILDRIKNNEYTYIINTAEGRQAIEDSKVLRRGALAEKVNYTTTLNAAFAACMAHTADDRNTVTSVQELHARINNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZZ3</accession>
    <name>D0YZZ3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 5">Thymidylate synthase</fullName>
            <shortName evidence="5">TS</shortName>
            <shortName evidence="5">TSase</shortName>
            <ecNumber evidence="1 5">2.1.1.45</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">thyA</name>
        <name evidence="8" type="ORF">VDA_002856</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + dUMP = 7,8-dihydrofolate + dTMP</text>
            <dbReference type="Rhea" id="RHEA:12104"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:57451"/>
            <dbReference type="ChEBI" id="CHEBI:63528"/>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
            <dbReference type="EC" id="2.1.1.45"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Pyrimidine metabolism; dTTP biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.45" evidence="1 5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301209.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002856"/>
    <dbReference type="EnsemblBacteria" id="EEZ41824">
        <property type="protein sequence ID" value="EEZ41824"/>
        <property type="gene ID" value="VDA_002856"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1212177at2"/>
    <dbReference type="UniPathway" id="UPA00575"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004799">
        <property type="term" value="F:thymidylate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006231">
        <property type="term" value="P:dTMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006235">
        <property type="term" value="P:dTTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00351">
        <property type="entry name" value="TS_Pyrimidine_HMase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.572.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00008">
        <property type="entry name" value="Thymidy_synth_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045097">
        <property type="entry name" value="Thymidate_synth/dCMP_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023451">
        <property type="entry name" value="Thymidate_synth/dCMP_Mease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036926">
        <property type="entry name" value="Thymidate_synth/dCMP_Mease_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000398">
        <property type="entry name" value="Thymidylate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020940">
        <property type="entry name" value="Thymidylate_synthase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11548">
        <property type="entry name" value="PTHR11548"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00303">
        <property type="entry name" value="Thymidylat_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00108">
        <property type="entry name" value="THYMDSNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55831">
        <property type="entry name" value="SSF55831"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03284">
        <property type="entry name" value="thym_sym"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00091">
        <property type="entry name" value="THYMIDYLATE_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4 5" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thymidylat_synt" evidence="7">
        <location>
            <begin position="2"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="160"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="160"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="22"/>
        </location>
        <ligand>
            <name>dUMP</name>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="180"/>
            <end position="183"/>
        </location>
        <ligand>
            <name>dUMP</name>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>dUMP</name>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="221"/>
            <end position="223"/>
        </location>
        <ligand>
            <name>dUMP</name>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="282"/>
        </location>
        <ligand>
            <name>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ41824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="283" mass="32602" checksum="D7A4FA8578FC4404" modified="2010-01-19" version="1">MKQYLNLCQRIVDDGVWVENERTGKRCLTVISADLTYDVANNQFPLITTRKSFWKAAIAELLGYIRGYDNAADFRALGTKTWDMNANDNQAWLNNPHRKGDDDMGRVYGVQGRSWRKPDGSTLDQLRKIVDDLSRGIDDRGEILTFYNPGEFDMGCLRPCMHTHTFSLLGDTLYLTSYQRSCDVPLGLNFNQIQVFTLLALMAQITGKKPGQAYHKIINAHIYEDQLELMRDVQLKREPFPSPQLKINPNIKSLEDLETWVTMDDFEVIGYEHHEPIKYPFSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZZ8</accession>
    <name>D0YZZ8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA mismatch repair protein MutH</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Methyl-directed mismatch repair protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">mutH</name>
        <name evidence="6" type="ORF">VDA_002861</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the MutH family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301232.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002861"/>
    <dbReference type="EnsemblBacteria" id="EEZ41829">
        <property type="protein sequence ID" value="EEZ41829"/>
        <property type="gene ID" value="VDA_002861"/>
    </dbReference>
    <dbReference type="GeneID" id="57340850"/>
    <dbReference type="eggNOG" id="COG3066">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1154974at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006304">
        <property type="term" value="P:DNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00583">
        <property type="entry name" value="MutH_Sau3AI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00759">
        <property type="entry name" value="MutH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004230">
        <property type="entry name" value="DNA_mismatch_repair_MutH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011337">
        <property type="entry name" value="DNA_rep_MutH/RE_typeII_Sau3AI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037057">
        <property type="entry name" value="DNA_rep_MutH/T2_RE_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02976">
        <property type="entry name" value="MutH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00927">
        <property type="entry name" value="MutH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02248">
        <property type="entry name" value="mutH_TIGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="2 4 6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MutH" evidence="5">
        <location>
            <begin position="53"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="222" mass="24631" checksum="6A8285F6D63C6DA6" modified="2010-01-19" version="1">MRPTPLSENELLQRAQELAGLTLGELAYQAGIVVPPDLRRDKGWVGQLLEWHLGASAGSKPVPDFAELGIELKTIPIGYNGKPLETTFVCVAPLIGVQGLSWQQSHIRHKLARVLWIPVEGERDLPLADRHVGSPLIWSPSAQEEAQLQQDWEELMDMIVLGQVEQITARHGEVLQLRPKAANSKALTEAYGANGQPIKTLPRGFYLKTNFTAAILERYFIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z054</accession>
    <name>D0Z054_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_002917</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the LptF/LptG family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301338.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002917"/>
    <dbReference type="EnsemblBacteria" id="EEZ41885">
        <property type="protein sequence ID" value="EEZ41885"/>
        <property type="gene ID" value="VDA_002917"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0795">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1558251at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030923">
        <property type="entry name" value="LptG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005495">
        <property type="entry name" value="LptG/LptF_permease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33529">
        <property type="entry name" value="PTHR33529"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03739">
        <property type="entry name" value="LptF_LptG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04408">
        <property type="entry name" value="LptG_lptG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="275"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="301"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="331"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00026081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ41885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="356" mass="39646" checksum="37D33888D3D04D2C" modified="2010-01-19" version="1">MFKILDWYIGRTIIGTTALTLSTLVGLSAIIKYVEQLRKVGQGTYDLWNALIFVLLSVPRDIEMFFPMAVLLGALIGLGMLASSSELVVMQAAGFSKLDIGLSTLKTAVPLMLMVMLLGQWGAPQAQKAARDLRTFWTSGGNMLSVQSGVWAKDGNDFIYIARVHEQKELDGINIWEFNGKNKLTQSVFAEKAQYNAEKGWSLKYVTVTDFAPIEIKETKYPTLDWQTTLTPDKLAIVTVKPEELSLSGVYNYVQYLKESKQDASRYELAFWRKALQPVSIAVMMLLALSFVFGPLRSVTMGARVLSGVIFGFAFYISNEVFGPMSQVYRLPPVIGALAPSMVFLAITIYLLKRKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0B8</accession>
    <name>D0Z0B8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GTPase Obg</fullName>
            <ecNumber evidence="5">3.6.5.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">GTP-binding protein Obg</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">obg</name>
        <name evidence="8" type="ORF">VDA_002981</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.-" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301454.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="SMR" id="D0Z0B8"/>
    <dbReference type="STRING" id="675817.VDA_002981"/>
    <dbReference type="EnsemblBacteria" id="EEZ41949">
        <property type="protein sequence ID" value="EEZ41949"/>
        <property type="gene ID" value="VDA_002981"/>
    </dbReference>
    <dbReference type="GeneID" id="57340707"/>
    <dbReference type="eggNOG" id="COG0536">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="603226at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01898">
        <property type="entry name" value="Obg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.210.12">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01454">
        <property type="entry name" value="GTPase_Obg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014100">
        <property type="entry name" value="GTP-bd_Obg/CgtA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006074">
        <property type="entry name" value="GTP1-OBG_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006169">
        <property type="entry name" value="GTP1_OBG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036726">
        <property type="entry name" value="GTP1_OBG_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045086">
        <property type="entry name" value="OBG_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11702">
        <property type="entry name" value="PTHR11702"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01018">
        <property type="entry name" value="GTP1_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002401">
        <property type="entry name" value="GTP_bd_Obg/CgtA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82051">
        <property type="entry name" value="SSF82051"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02729">
        <property type="entry name" value="Obg_CgtA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00905">
        <property type="entry name" value="GTP1_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51883">
        <property type="entry name" value="OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Obg" evidence="7">
        <location>
            <begin position="1"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="OBG-type G" evidence="6">
        <location>
            <begin position="160"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="166"/>
            <end position="173"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="191"/>
            <end position="195"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="213"/>
            <end position="216"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="283"/>
            <end position="286"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="314"/>
            <end position="316"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ41949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="391" mass="43741" checksum="ED245F52231DB091" modified="2010-01-19" version="1">MKFVDEAVIRVDAGDGGNGVVSFRREKYVPKGGPDGGDGGDGGDVYLVADENLNTLIDYRFQRFYAAERGENGRGGNCTGKRGEDIILSVPVGTRAVDEETGEVIADLTEHGMKLMVAKGGFHGLGNTRFKSSVNRAPRQKTMGTKGEIRHLRLELLLLADVGMLGLPNAGKSTFIRAVSAAKPKVADYPFTTLVPSLGVVRAGADRSFVVADIPGLIEGAADGAGLGIRFLKHLERCRVLLHMIDLLPADGSDPVENTFTIINELEQYSEKLTGKPRWLVFNKVDLMPEDEANEKIQEILDALAWEDKYYRISALNRLGTQELCYDLMEFIEQLPREIEIEEEKQEKVEFKWDDYHAEQVKRHQKDDDDDDDDWEDWNEDDYDVEIIYKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0D5</accession>
    <name>D0Z0D5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002998</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301511.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002998"/>
    <dbReference type="EnsemblBacteria" id="EEZ41966">
        <property type="protein sequence ID" value="EEZ41966"/>
        <property type="gene ID" value="VDA_002998"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031NZV">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="902721at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021254">
        <property type="entry name" value="DUF2806"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10987">
        <property type="entry name" value="DUF2806"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03899">
        <property type="entry name" value="TIGR03899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="274" mass="31577" checksum="F5BEEBF5A1932492" modified="2010-01-19" version="1">MANLPFARTSSSLISSKQRIERLAKQNYIAELINSSELSLIERLEHRERYLAQSKQNNLEQIIKLAHSYAGEENSRELDIDWWHHYLQLAQDIYSPQMQKVWAKALIQETLNPHSISLKALQTLAQLTHYELAIFKKALNTCWQLGNQDNNSKLLSQIVITNKRLFSNQYLEIDLLPNTLTVSMLMILMEAGLLLKTELSTKAIAKNSALTLSKGQHTYQLVSLKTKSTFSYYRLSIIGQELEHLLGDHDNSGYRKNIIDTLSRHFQIESDKHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0D7</accession>
    <name>D0Z0D7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">Adenylyl-sulfate kinase</fullName>
            <ecNumber evidence="2 3">2.7.1.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">APS kinase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">ATP adenosine-5'-phosphosulfate 3'-phosphotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Adenosine-5'-phosphosulfate kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">cysC</name>
        <name evidence="4" type="ORF">VDA_003000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 3">Catalyzes the synthesis of activated sulfate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 3">
            <text>adenosine 5'-phosphosulfate + ATP = 3'-phosphoadenylyl sulfate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24152"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58243"/>
            <dbReference type="ChEBI" id="CHEBI:58339"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.25"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 2 3">Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the APS kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.25" evidence="2 3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301515.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003000"/>
    <dbReference type="EnsemblBacteria" id="EEZ41968">
        <property type="protein sequence ID" value="EEZ41968"/>
        <property type="gene ID" value="VDA_003000"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0529">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1574819at2"/>
    <dbReference type="UniPathway" id="UPA00140">
        <property type="reaction ID" value="UER00205"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004020">
        <property type="term" value="F:adenylylsulfate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070814">
        <property type="term" value="P:hydrogen sulfide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000103">
        <property type="term" value="P:sulfate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02027">
        <property type="entry name" value="APSK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00065">
        <property type="entry name" value="Adenylyl_sulf_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002891">
        <property type="entry name" value="APS_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00455">
        <property type="entry name" value="apsK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 3 4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Phosphoserine intermediate" evidence="2">
        <location>
            <position position="111"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="37"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="205" mass="23223" checksum="92D3630EF4470D3F" modified="2010-01-19" version="1">MTSVLVKDNVIWHQHLVNKQIRGELKQQRPCILWFTGLSGAGKSTIAGALEKELVQRGYHTYLLDGDNVRHGLCRDLGFSIEDRRENIRRIGEVAALMADAGLIVLSAFISPERRERQLVRDLVADGEFIEVFVDTSLVECERRDPKGLYKKARAGEIKQFTGIDSIYEKPLEPEIHLVSGSDNHIEDLVSKCVDELYARHIISK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0F9</accession>
    <name>D0Z0F9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">50S ribosomal protein L9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rplI</name>
        <name evidence="10" type="ORF">VDA_003023</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Binds to the 23S rRNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the bacterial ribosomal protein bL9 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301592.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003023"/>
    <dbReference type="EnsemblBacteria" id="EEZ41990">
        <property type="protein sequence ID" value="EEZ41990"/>
        <property type="gene ID" value="VDA_003023"/>
    </dbReference>
    <dbReference type="GeneID" id="57340524"/>
    <dbReference type="eggNOG" id="COG0359">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1959318at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.430.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.5.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00503">
        <property type="entry name" value="Ribosomal_L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000244">
        <property type="entry name" value="Ribosomal_L9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009027">
        <property type="entry name" value="Ribosomal_L9/RNase_H1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020594">
        <property type="entry name" value="Ribosomal_L9_bac/chp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020069">
        <property type="entry name" value="Ribosomal_L9_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036791">
        <property type="entry name" value="Ribosomal_L9_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020070">
        <property type="entry name" value="Ribosomal_L9_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036935">
        <property type="entry name" value="Ribosomal_L9_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21368">
        <property type="entry name" value="PTHR21368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03948">
        <property type="entry name" value="Ribosomal_L9_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01281">
        <property type="entry name" value="Ribosomal_L9_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55653">
        <property type="entry name" value="SSF55653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55658">
        <property type="entry name" value="SSF55658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00158">
        <property type="entry name" value="L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00651">
        <property type="entry name" value="RIBOSOMAL_L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7 10" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 7" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="RIBOSOMAL_L9" evidence="9">
        <location>
            <begin position="13"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="37"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ41990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="150" mass="15680" checksum="14B0C0E1DEDEBECE" modified="2010-01-19" version="1">MQVILLDKIANLGGLGDQVNVKAGYARNFLIPQAKAVMATKANVEMFEARRAELEAKVAEQQAAAQARAEALNALEAVVIASKAGDEGKLFGSIGTRDIADAVTAAGVALVKSEVRLPEGALRTTGEFEVSIQLNSDVFATVKLNVVAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0K2</accession>
    <name>D0Z0K2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">UPF0056 membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_003066</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the UPF0056 (MarC) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301738.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ42033">
        <property type="protein sequence ID" value="EEZ42033"/>
        <property type="gene ID" value="VDA_003066"/>
    </dbReference>
    <dbReference type="GeneID" id="57340463"/>
    <dbReference type="eggNOG" id="COG2095">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1323133at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002771">
        <property type="entry name" value="Multi_antbiot-R_MarC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33508">
        <property type="entry name" value="PTHR33508"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01914">
        <property type="entry name" value="MarC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00427">
        <property type="entry name" value="TIGR00427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="39"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="68"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="111"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="180"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ42033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="210" mass="22635" checksum="F3C5F33B91F481F1" modified="2010-01-19" version="1">MLSVLLTQFVLIWAVIDPIGSIPVYLSQTHHLSPHQRRLVAIKAILIATGILLFFVIVGQILLEAMQIPLPAFQAAGGLVLLLFALTMIFGESKVEQECKLSEQELQHSELGALAVYPLAVPSIASPGAMMAVVMLTDNNRYSFIDQAITTSVMLSVLVITLILLLGASKIQRYIGDVGAAIISRVMGLILAAVALNNLLIGIRDFYLAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0P9</accession>
    <name>D0Z0P9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">3'(2'),5'-bisphosphate nucleotidase CysQ</fullName>
            <ecNumber evidence="1">3.1.3.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">3'-phosphoadenosine 5'-phosphate phosphatase</fullName>
            <shortName evidence="1">PAP phosphatase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">cysQ</name>
        <name evidence="2" type="ORF">VDA_003113</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Converts adenosine-3',5'-bisphosphate (PAP) to AMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>adenosine 3',5'-bisphosphate + H2O = AMP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10040"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58343"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="3.1.3.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the inositol monophosphatase superfamily. CysQ family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.7" evidence="1"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301898.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003113"/>
    <dbReference type="EnsemblBacteria" id="EEZ42080">
        <property type="protein sequence ID" value="EEZ42080"/>
        <property type="gene ID" value="VDA_003113"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1218">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1741160at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008441">
        <property type="term" value="F:3'(2'),5'-bisphosphate nucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046855">
        <property type="term" value="P:inositol phosphate dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006790">
        <property type="term" value="P:sulfur compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02095">
        <property type="entry name" value="CysQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006240">
        <property type="entry name" value="CysQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01331">
        <property type="entry name" value="bisphos_cysQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="1">
        <location>
            <begin position="89"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="67"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="87"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="274" mass="30338" checksum="413741D25BF65003" modified="2010-01-19" version="1">MMTTLLPQVIDIAKASGQLIADIYQQGQFEQMIKQDDTPVTSADLAAHQLVVERLQALTPDIPVLSEEDTKVPLSIRSQWPRYWLIDPLDGTQEFIAGSGDFATIIALIENHQPVMGVVYAPMSQVTYYASRGQGAFKLLPNGEPQQIQTRKLSVDTHSLTVAISRRQKQETIVERLGARYQLELLPLGSASLKACLVAEGKADCYLRLGPTGEWDTAATQCIVEEAGGCIVNTHIEPLTYNLRETLENPNFITLGDTHLPWSQILVPDDRMPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0R9</accession>
    <name>D0Z0R9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Glutamine synthetase</fullName>
            <ecNumber evidence="2 7">6.3.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_003133</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + L-glutamate + NH4(+) = ADP + H(+) + L-glutamine + phosphate</text>
            <dbReference type="Rhea" id="RHEA:16169"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.1.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="6">Oligomer of 12 subunits arranged in the form of two hexagons.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the glutamine synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.1.2" evidence="2 7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301960.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003133"/>
    <dbReference type="EnsemblBacteria" id="EEZ42100">
        <property type="protein sequence ID" value="EEZ42100"/>
        <property type="gene ID" value="VDA_003133"/>
    </dbReference>
    <dbReference type="GeneID" id="57340638"/>
    <dbReference type="eggNOG" id="COG0174">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="416474at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004356">
        <property type="term" value="F:glutamate-ammonia ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006542">
        <property type="term" value="P:glutamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008147">
        <property type="entry name" value="Gln_synt_b-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036651">
        <property type="entry name" value="Gln_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008146">
        <property type="entry name" value="Gln_synth_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027303">
        <property type="entry name" value="Gln_synth_gly_rich_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004809">
        <property type="entry name" value="Gln_synth_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001637">
        <property type="entry name" value="Gln_synth_I_adenylation_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027302">
        <property type="entry name" value="Gln_synth_N_conserv_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00120">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03951">
        <property type="entry name" value="Gln-synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01230">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54368">
        <property type="entry name" value="SSF54368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="SSF55931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00653">
        <property type="entry name" value="GlnA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00180">
        <property type="entry name" value="GLNA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00182">
        <property type="entry name" value="GLNA_ADENYLATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00181">
        <property type="entry name" value="GLNA_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gln-synt_C" evidence="8">
        <location>
            <begin position="102"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-AMP-tyrosine" evidence="4">
        <location>
            <position position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR604809-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ42100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="469" mass="51627" checksum="A2ADEC2854FF8082" modified="2010-01-19" version="1">MSVENVLALIQENEVKFVDLRFTDTKGKEQHISIPAHQIDADFFEEGKMFDGSSVAGWKGINESDMVMMPDASSAVLDPFTEESTLNIRCDILEPATMQGYDRDPRSIAKRAEDFMRSTGIADTVLVGPEPEFFLFDDVKFHTDMSGSFFKIDDIEAAWNTGSDVEGGNKGHRPGVKGGYFPVAPVDSSQDIRSAMCLIMEEMGLVVEAHHHEVATAGQNEIATRFNTLTTKADEIQIYKYVVHNVAHAFGKTATFMPKPLVGDNGSGMHVHQSLAKDGVNLFAGDKYGGLSEMALYYIGGIIKHARAINAFANPATNSYKRLVPGFEAPVMLAYSARNRSASIRIPVVPSPKARRIEVRFPDPAANPYLAFAAMLMAGLDGIINKIHPGEAMDKDLYDLPAEEAAEIPTVAESLKDALQYLDDDREFLTAGGVFSNDFIDSYIKLKAQDVEKVNMTTHPLEFELYYSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0Z4</accession>
    <name>D0Z0Z4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_003208</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0073 (Hly-III) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302168.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003208"/>
    <dbReference type="EnsemblBacteria" id="EEZ42175">
        <property type="protein sequence ID" value="EEZ42175"/>
        <property type="gene ID" value="VDA_003208"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1272">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1659567at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019835">
        <property type="term" value="P:cytolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004254">
        <property type="entry name" value="AdipoR/HlyIII-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005744">
        <property type="entry name" value="Hy-lIII"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20855">
        <property type="entry name" value="PTHR20855"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03006">
        <property type="entry name" value="HlyIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01065">
        <property type="entry name" value="hlyIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="48"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="111"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="142"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="166"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="195"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ42175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="219" mass="24040" checksum="2C2A5286F3A69457" modified="2010-01-19" version="1">MDKKPQLAAGYSVKEEIANSVSHGLGMIFGIVGLVLLLVQAVNAKADALSIVSLSIYGGSMILLYLASTLYHAIPFERAKRALKTFDHCAIFLLIAGTYTPFLLISLRTPLAITLMVIIWLLALMGIAAKIVFVYRFKKLSLITYLTMGWLSLIAIYQLAMALSTGGLVLLALGGLIYSIGVVFYVNKRIPYNHAIWHLFVLGGSICHFCAIYFYVKSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z119</accession>
    <name>D0Z119_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ATP synthase subunit delta</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">ATP synthase F(1) sector subunit delta</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">F-type ATPase subunit delta</fullName>
            <shortName evidence="7">F-ATPase subunit delta</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">atpH</name>
        <name evidence="8" type="ORF">VDA_003233</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.</text>
    </comment>
    <comment type="function">
        <text evidence="7">This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the ATPase delta chain family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302239.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003233"/>
    <dbReference type="EnsemblBacteria" id="EEZ42200">
        <property type="protein sequence ID" value="EEZ42200"/>
        <property type="gene ID" value="VDA_003233"/>
    </dbReference>
    <dbReference type="GeneID" id="57340360"/>
    <dbReference type="eggNOG" id="COG0712">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1937493at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01416">
        <property type="entry name" value="ATP_synth_delta_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026015">
        <property type="entry name" value="ATP_synth_OSCP/delta_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020781">
        <property type="entry name" value="ATPase_OSCP/d_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000711">
        <property type="entry name" value="ATPase_OSCP/dsu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11910">
        <property type="entry name" value="PTHR11910"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00213">
        <property type="entry name" value="OSCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00125">
        <property type="entry name" value="ATPASEDELTA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47928">
        <property type="entry name" value="SSF47928"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01145">
        <property type="entry name" value="ATP_synt_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00389">
        <property type="entry name" value="ATPASE_DELTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0139">CF(1)</keyword>
    <keyword evidence="2 7" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ42200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="177" mass="19426" checksum="4311A5F656F08651" modified="2010-01-19" version="1">MSELATIARPYAKAAFDFAVEKNTLAPWAEMLLFASEVAENDTMQDILDSGYAADKLSEIFVAVCGEQLDEHGQNLLKVMAENGRLKALPDVYHEFMLLKNELEKTVEAVVVSAIELNDAQRDAIEAKLSTRLERKVKLSCSVDETLIAGVVIRAGDLVIDNSVRGKLARLSDTLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z142</accession>
    <name>D0Z142_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_003256</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302308.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003256"/>
    <dbReference type="EnsemblBacteria" id="EEZ42223">
        <property type="protein sequence ID" value="EEZ42223"/>
        <property type="gene ID" value="VDA_003256"/>
    </dbReference>
    <dbReference type="GeneID" id="57340329"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1591366at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08417">
        <property type="entry name" value="PBP2_Nitroaromatics_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037402">
        <property type="entry name" value="YidZ_PBP2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="9"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ42223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="314" mass="35721" checksum="E996418942EAFC8A" modified="2010-01-19" version="1">MELEEVYRRDLNLLVALKVLLEESSVSKAAVRLNLSQSAMSRVLGRLRHLLNDPLFTRQGQHLIPTQRALELNEQLHDPLESLRILLTPNDFQPELCDQRFTIATTDYAMQTILPFALPRIYQEAPNISLEFAPLQHDHLLEQLTTDGCDMAICRPIGSVEPLSSEHLGLVSVFCLLSRHHPLADKPLTLSDYLTFPHAMIAISDGVKALVDDALRGHPERKMVLRAYHLEAALAIVESMPLIITVPADLAYLVAEKHNLVIKPLPFDFKPFDYSLIWHPRCEHSASQLWLRNLIKEECSRLIDTRIHDMGLME</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z148</accession>
    <name>D0Z148_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HTH-type transcriptional regulator IlvY</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_003262</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ42229">
        <property type="protein sequence ID" value="EEZ42229"/>
        <property type="gene ID" value="VDA_003262"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08430">
        <property type="entry name" value="PBP2_IlvY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037404">
        <property type="entry name" value="IlvY_PBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="2"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ42229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="293" mass="32568" checksum="9F350D135857BDAF" modified="2010-01-19" version="1">MMNLKNLQHFIHLAESKSFTVTAQKTHISLSALSRVIQRLEQELEQSLFIRDNRSVELTAAGKELLPVAIGIVEQWHQLKTQLSTDQHLLRGKLTLFCSVTASYSHLPQLVTELRQTHPQIEIQLLTGDPAQAIEKVLNDEADIAIAAKPKHLSNKLTFIEFDQVTLTVISPLLVGQSLQPTHQISAQWQTLPFILPESGTARDHSNDWLRDNQINPTIYAQVAGHEAIVSMVALGCGVGIAPDVVIDNSPMKDRVFKHNDQNIKPLALGLCCKKSRAHEPLLAALMQLCQSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z161</accession>
    <name>D0Z161_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Thiazole biosynthesis protein ThiH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_003275</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003275"/>
    <dbReference type="EnsemblBacteria" id="EEZ42242">
        <property type="protein sequence ID" value="EEZ42242"/>
        <property type="gene ID" value="VDA_003275"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0502">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010722">
        <property type="entry name" value="BATS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012726">
        <property type="entry name" value="ThiH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034428">
        <property type="entry name" value="ThiH/NoCL/HydG-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43583">
        <property type="entry name" value="PTHR43583"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43583:SF1">
        <property type="entry name" value="PTHR43583:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06968">
        <property type="entry name" value="BATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00301">
        <property type="entry name" value="2-iminoacetate_synthase_(ThiH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00876">
        <property type="entry name" value="BATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02351">
        <property type="entry name" value="thiH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="6">
        <location>
            <begin position="74"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ42242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="374" mass="43051" checksum="66F9DAB6ECE53436" modified="2010-01-19" version="1">MGSKMSFSSIWQQLNWDDLRLNIYSKTAQDVERALSKTRCDLSDFQALISPAAESYLEQLAIKAQERTRQRFGHTMGLYVPLYLSNLCANSCTYCGFSMENKLKRKVLNTAEIEQECQALKRKGFDSILLVTGEHETKVGMTYLAQAVEQIKPYFSYLALEVQPLEQEEYVQLRALGLNGVMVYQETYHQREYAKHHLRGKKQDFHYRLETADRLAQAGIDKIGLGALIGLEDWRVDSFFVARHLQYLEQRYWQSRYSISFPRLRPCTGGVEPKSVMTDRQLVQLICAYRLFNGEVELSLSTRESAFFRDNVASLGITTMSAESKTQPGGYAEQALSELEQFTIDDARSVQDVAARLQQQGLTPVWKDWQHQYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z162</accession>
    <name>D0Z162_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Xaa-Pro aminopeptidase</fullName>
            <ecNumber evidence="5">3.4.11.9</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_003276</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M24B family.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.9" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302361.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003276"/>
    <dbReference type="EnsemblBacteria" id="EEZ42243">
        <property type="protein sequence ID" value="EEZ42243"/>
        <property type="gene ID" value="VDA_003276"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0006">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="415910at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110165">
        <property type="term" value="C:cellular anatomical entity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01085">
        <property type="entry name" value="APP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_NTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000587">
        <property type="entry name" value="Creatinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033740">
        <property type="entry name" value="Pept_M24B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032416">
        <property type="entry name" value="Peptidase_M24_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01321">
        <property type="entry name" value="Creatinase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16188">
        <property type="entry name" value="Peptidase_M24_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="SSF53092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="SSF55920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Creatinase_N" evidence="3">
        <location>
            <begin position="8"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M24" evidence="2">
        <location>
            <begin position="309"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M24_C" evidence="4">
        <location>
            <begin position="534"/>
            <end position="593"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ42243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="596" mass="65393" checksum="C37561FEF2D2203B" modified="2010-01-19" version="1">MQAVIAQRVEQLRQWLIANDYDALLIPHEDEYLGEYIPVHNERLEWATGFTGSAGMAIITRDQAAIFVDGRYVVQVRKQVPGDVYQYRHLIEEPPMQWVLETLASGSKVVLDPRLHSQAWFERTQQQVGEELALISIDANPIDSLWIDRPAATLSDAILMSEQYAGVSSSEKRNQIAAVLKKNKADAAVISQIDAIAWLLNIRGNDVPRLPVLLSNLIIDANGDVSFYIDANRLPAEFAAHVGAGVTVKAPEQLQADLAAFTKQTVMVDPNSCNAWTVQELQQAQANILPAADPCALPKAMKNPTEAAGMKACHIRDGVAMAKFLAWLDAQVAQGILLDEGQLADQLWAFRAQDPSCSDMSFDTISAAASNAAMCHYNHQNQPQPSALELNSLYLVDSGGQYPDGTTDITRTVAIGTPSAEQKHAFTLVLKGHIALASARFPKGTTGSQLDALARQHLWAHGFDYDHGTGHGVGHFLSVHEGPQRIAKVYNPTALQPGMVLSNEPGYYRADAFGIRIENLEIVVEIPTQGDMTVLGFESLTRAPIDKRVIDTALMTDNEIEWLNQYHQKVWQDVSPALTGEDLTWLEQATAPLTRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z170</accession>
    <name>D0Z170_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Twin-arginine translocation protein TatB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003284</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003284"/>
    <dbReference type="EnsemblBacteria" id="EEZ42251">
        <property type="protein sequence ID" value="EEZ42251"/>
        <property type="gene ID" value="VDA_003284"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1826">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="74" mass="8438" checksum="F0B6069AC289914B" modified="2010-01-19" version="1">MANSVKDELSQELKIQELQENLRKAEQMNMKDLSPDLQKSVDELKKAADEVQRPYSPEAKKSEQTSATTSDKQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1B6</accession>
    <name>D0Z1B6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Two-component system response regulator OmpR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_003330</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302504.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003330"/>
    <dbReference type="EnsemblBacteria" id="EEZ42297">
        <property type="protein sequence ID" value="EEZ42297"/>
        <property type="gene ID" value="VDA_003330"/>
    </dbReference>
    <dbReference type="GeneID" id="57340225"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="817710at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="6"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="135"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="135"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ42297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="239" mass="27358" checksum="33239D92E800C9B9" modified="2010-01-19" version="1">MQENFKILVVDDDMRLRALLERYLSEQGFQVRSVANGEQMDRLLARENFHLMVLDLMLPGEDGLSICRRLRNANNMLPILMLTAKGDEVDRIVGLEVGADDYLPKPFNPRELLARIRAVLRRQTIEAPGAPSIDSKVIEFGDFRLNLGTREMFRGDEPMPLTSGEFAVLKALVTNAREPMSRDKLMNMARGREYSAMERSIDVQISRLRRMVEEDPSRPRYIQTVWGLGYVFVPDGQEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1G6</accession>
    <name>D0Z1G6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glycerol kinase</fullName>
            <ecNumber evidence="5">2.7.1.30</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">ATP:glycerol 3-phosphotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Glycerokinase</fullName>
            <shortName evidence="5">GK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">glpK</name>
        <name evidence="9" type="ORF">VDA_003380</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + glycerol = ADP + H(+) + sn-glycerol 3-phosphate</text>
            <dbReference type="Rhea" id="RHEA:21644"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17754"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.30"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="5">Inhibited by fructose 1,6-bisphosphate (FBP).</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the FGGY kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.30" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302608.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003380"/>
    <dbReference type="EnsemblBacteria" id="EEZ42347">
        <property type="protein sequence ID" value="EEZ42347"/>
        <property type="gene ID" value="VDA_003380"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0554">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="233605at2"/>
    <dbReference type="UniPathway" id="UPA00618">
        <property type="reaction ID" value="UER00672"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004370">
        <property type="term" value="F:glycerol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019563">
        <property type="term" value="P:glycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006072">
        <property type="term" value="P:glycerol-3-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00186">
        <property type="entry name" value="Glycerol_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000577">
        <property type="entry name" value="Carb_kinase_FGGY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018485">
        <property type="entry name" value="Carb_kinase_FGGY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018483">
        <property type="entry name" value="Carb_kinase_FGGY_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018484">
        <property type="entry name" value="Carb_kinase_FGGY_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005999">
        <property type="entry name" value="Glycerol_kin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02782">
        <property type="entry name" value="FGGY_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00370">
        <property type="entry name" value="FGGY_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000538">
        <property type="entry name" value="GlpK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01311">
        <property type="entry name" value="glycerol_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00933">
        <property type="entry name" value="FGGY_KINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00445">
        <property type="entry name" value="FGGY_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5" id="KW-0319">Glycerol metabolism</keyword>
    <keyword evidence="5 6 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FGGY_N" evidence="7">
        <location>
            <begin position="7"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="FGGY_C" evidence="8">
        <location>
            <begin position="263"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="85"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="247"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="15"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="19"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="269"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="312"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="316"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="331"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="413"/>
            <end position="417"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ42347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="503" mass="55098" checksum="D271E523E597F097" modified="2010-01-19" version="1">MTTEQKYIVALDQGTTSSRAVVLDQNANIICSSQREFTQIYPKSGWVEHDPLEIYATQSSTLVEALAKAGIRSDQVAAIGITNQRETTIVWDKTTGKPVYNAIVWQCRRTAYICEDLKQQGLTDYIRDNTGLVVDPYFSGTKIKWILDHVEGAREQAEAGNLLFGTVDTWLIWKMTQGRVHVTDYTNASRTMLFNINTLEWDEKLLKALDIPLSMMPEVKPSSQVYGQTNIGGKGGTRIPIAGIAGDQQAALFGQMCVEPGQAKNTYGTGCFLLMNTGKEKVSSSNGLLTTLACGPKGDVAYALEGAVFMGGASIQWLRDEVKLLDDAKDSEYFAEKVGSANGVYVVPAFTGLGAPYWDPYARGAIVGLTRGVNSNHIIRATLESVAYQTRDVLDAMQADSGIKLGTLRVDGGAVANNFLMQFQSDILAAEVHRPVVTEVTALGAAYLAGLAVGFWDSIDELQGKAQLDRKFVPCQDDNKRNRRYRGWKRAVECAKGWALDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1N6</accession>
    <name>D0Z1N6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">50S ribosomal protein L24</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rplX</name>
        <name evidence="6" type="ORF">VDA_003450</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.</text>
    </comment>
    <comment type="function">
        <text evidence="3">One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 4">Belongs to the universal ribosomal protein uL24 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302806.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003450"/>
    <dbReference type="EnsemblBacteria" id="EEZ42417">
        <property type="protein sequence ID" value="EEZ42417"/>
        <property type="gene ID" value="VDA_003450"/>
    </dbReference>
    <dbReference type="GeneID" id="57340093"/>
    <dbReference type="eggNOG" id="COG0198">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2040741at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06089">
        <property type="entry name" value="KOW_RPL26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01326_B">
        <property type="entry name" value="Ribosomal_L24_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041988">
        <property type="entry name" value="KOW_RPL26/RPL24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003256">
        <property type="entry name" value="Ribosomal_L24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005825">
        <property type="entry name" value="Ribosomal_L24/26_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12903">
        <property type="entry name" value="PTHR12903"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00467">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17136">
        <property type="entry name" value="ribosomal_L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00739">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01079">
        <property type="entry name" value="rplX_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01108">
        <property type="entry name" value="RIBOSOMAL_L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 4 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="KOW" evidence="5">
        <location>
            <begin position="4"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00029550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ42417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="103" mass="11032" checksum="AE793EFD62528024" modified="2010-01-19" version="1">MAAKIRRNDEVIVLTGKDKGKKGKVSKVLATGKVIVDGINLVKKHQKPVPAMGIQGGIVEKEAAIDASNVAIVNGEGKADRVGFRFEDGKKVRFFKSTGETIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1R8</accession>
    <name>D0Z1R8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Serine--pyruvate aminotransferase/L-alanine:glyoxylate aminotransferase</fullName>
            <ecNumber evidence="8">2.6.1.44</ecNumber>
            <ecNumber evidence="8">2.6.1.51</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_003482</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 4 6">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.44" evidence="8"/>
    <dbReference type="EC" id="2.6.1.51" evidence="8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303570.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003482"/>
    <dbReference type="EnsemblBacteria" id="EEZ42449">
        <property type="protein sequence ID" value="EEZ42449"/>
        <property type="gene ID" value="VDA_003482"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0075">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="996960at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008453">
        <property type="term" value="F:alanine-glyoxylate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004760">
        <property type="term" value="F:serine-pyruvate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020578">
        <property type="entry name" value="Aminotrans_V_PyrdxlP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024169">
        <property type="entry name" value="SP_NH2Trfase/AEP_transaminase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000524">
        <property type="entry name" value="SPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00595">
        <property type="entry name" value="AA_TRANSFER_CLASS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3 4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_5" evidence="7">
        <location>
            <begin position="33"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="4">
        <location>
            <position position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000524-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ42449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="372" mass="40604" checksum="870CAF5B1AA750F7" modified="2010-01-19" version="1">MAITSFQPPRRVLMGPGPSDIYPQVLQALSRPTIGHLDPLFITMMDELKALLQYAFQTQNPFTIAVSAPGSAGMEACFVNLVEPGDKVVVCRNGVFGQRMVENVERCGGVAVTVDNTWGEPVSPELLEQTLNQHSDAKIVAFVHAETSTGALSDAKTLAEIARRFDCLTIVDAVTSLGGVPLLVDEWQLDAVYSGSQKCLSCVPGLAPLTFSAKALEKIASRQHKVQSWFLDQSLVLGYWNGGAKRSYHHTAPVNSLYALHEALLLLQQEGLEHAWQRHQEMHQELKAGLMELGIEFVVDEAYRLPQLNAVYIPQGVDDAAVRQTLLERYNLEIGAGLGDLAGKAWRIGLMGYGARAENVALCVKALAQTLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1W3</accession>
    <name>D0Z1W3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">UDP-N-acetylglucosamine 1-carboxyvinyltransferase</fullName>
            <ecNumber evidence="8">2.5.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Enoylpyruvate transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">UDP-N-acetylglucosamine enolpyruvyl transferase</fullName>
            <shortName evidence="8">EPT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">murA</name>
        <name evidence="10" type="ORF">VDA_003527</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>phosphoenolpyruvate + UDP-N-acetyl-alpha-D-glucosamine = phosphate + UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine</text>
            <dbReference type="Rhea" id="RHEA:18681"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:68483"/>
            <dbReference type="EC" id="2.5.1.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the EPSP synthase family. MurA subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.7" evidence="8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303700.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003527"/>
    <dbReference type="EnsemblBacteria" id="EEZ42494">
        <property type="protein sequence ID" value="EEZ42494"/>
        <property type="gene ID" value="VDA_003527"/>
    </dbReference>
    <dbReference type="GeneID" id="57339996"/>
    <dbReference type="eggNOG" id="COG0766">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="537477at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008760">
        <property type="term" value="F:UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019277">
        <property type="term" value="P:UDP-N-acetylgalactosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01555">
        <property type="entry name" value="UdpNAET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.65.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00111">
        <property type="entry name" value="MurA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001986">
        <property type="entry name" value="Enolpyruvate_Tfrase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036968">
        <property type="entry name" value="Enolpyruvate_Tfrase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013792">
        <property type="entry name" value="RNA3'P_cycl/enolpyr_Trfase_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005750">
        <property type="entry name" value="UDP_GlcNAc_COvinyl_MurA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00275">
        <property type="entry name" value="EPSP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55205">
        <property type="entry name" value="SSF55205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01072">
        <property type="entry name" value="murA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1 8" id="KW-0132">Cell division</keyword>
    <keyword evidence="3 8" id="KW-0133">Cell shape</keyword>
    <keyword evidence="6 8" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 8" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="7 8" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="EPSP_synthase" evidence="9">
        <location>
            <begin position="7"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphoenolpyruvate binding" evidence="8">
        <location>
            <begin position="22"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="UDP-N-acetylglucosamine binding" evidence="8">
        <location>
            <begin position="120"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="UDP-N-acetylglucosamine binding" evidence="8">
        <location>
            <begin position="160"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="115"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="305"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="327"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="2-(S-cysteinyl)pyruvic acid O-phosphothioketal" evidence="8">
        <location>
            <position position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ42494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="418" mass="44145" checksum="ABCB4072F0EA6CB4" modified="2010-01-19" version="1">MQKFRIQGGGPLCGEVAISGAKNAALPILFAALLAEEPVEVANVPKLRDIDTTMELLSRLGAKVSRNGSVHVDASGVNEYCAPYDLVKTMRASIWALGPLVARFGQGQVSLPGGCAIGARPVDLHITGLEQLGATITLEEGYVKAHVDGRLKGAHIVMDKVSVGATVTIMCAATLAEGQTIIENAAREPEIVDTADFLKAIGAKITGAGTDTIIIDGVERLGGGYHSVVPDRIETGTFLVAAAVSGGKIVCRGTKASLMDAVLAKLEEAGAKVETGDDWISLDMTDRELKAVNIRTAPHPGFPTDMQAQFSLLNLMAKGTGIITETIFENRFMHIPELIRMGAHAEIEGNTVICGDTEGLSGAQVMATDLRASASLVIAGSIAKGETIVDRIYHIDRGYERIEDKFSALGMNIERISE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z205</accession>
    <name>D0Z205_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001966</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299041.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001966"/>
    <dbReference type="EnsemblBacteria" id="EEZ40934">
        <property type="protein sequence ID" value="EEZ40934"/>
        <property type="gene ID" value="VDA_001966"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0699">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="546910at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G" evidence="1">
        <location>
            <begin position="36"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="387" mass="43327" checksum="B2905D1F493EAB53" modified="2010-01-19" version="1">MNRFFKKVYDYINPSVNPDIEPASKEWQKLVPTLWLLGKTGAGKSTIVQALTGDSRAEIGLGFQPCTQTASDYNYPTANPVVSFLDTRGLAEDNYDPKHDIEYCEGRSHALLVIMKAEEQDQSEVLQALKAIKKSKKIRHLLVVHTAINGISDEQERQRSITRHHNQVLDIWGINPDKLTEEQQLWYQPICVDLIPEIEQLEGLEQLQQALVAALPMLSLITEKNAHQTREEHNFSRLQTEILWYAGTAGASDAIPGIGIVAVPSIQGKMLHSLANQYGVTWNKQDYAEFIGMLGSGFLIQYLSKLGVNQLVKFIPIYGQTVGSATAAVMSFSSTYAIGRAACMYLYHKSKGETVSKDQMKQAFEQAFKSVKNVATEQAKMEQKHHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z209</accession>
    <name>D0Z209_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hypothetical transcriptional</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001970</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299050.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001970"/>
    <dbReference type="EnsemblBacteria" id="EEZ40938">
        <property type="protein sequence ID" value="EEZ40938"/>
        <property type="gene ID" value="VDA_001970"/>
    </dbReference>
    <dbReference type="GeneID" id="57341890"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1591366at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08417">
        <property type="entry name" value="PBP2_Nitroaromatics_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037402">
        <property type="entry name" value="YidZ_PBP2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="4"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="308" mass="36103" checksum="0F0D5D6C224892FC" modified="2010-01-19" version="1">MKNFDVNLLKVLEVLLQEKSVTAAACRLHLSQSAVSKQLAKLRETFHDPLFERAPHGLRPTPKALSLAPNIHQILRQVEQLTRPEDFDPASSRRKFHIDLVETAYTLTYPDFIPKMLEQAPEVSLISRTWNDDSLNQLLRCEIDLGIGIFEWDERSEMHYRTIPNELNYYLLGRDYPVCLMRKDHPSLQEEWNLETFLKYRHIEVSIGGLRRWLLEEVLALQNRHVDIAINMTDFRTAIKLCENSDLLMCYPSYPTHELQETSNLIVRPIPIHLDAGGYVLLWHRHFELDLSHQWLRELIIHGVKKLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2G2</accession>
    <name>D0Z2G2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7 8">3,4-dihydroxy-2-butanone 4-phosphate synthase</fullName>
            <shortName evidence="7 8">DHBP synthase</shortName>
            <ecNumber evidence="3 7 8">4.1.99.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ribB</name>
        <name evidence="9" type="ORF">VDA_000613</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 7 8">Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>D-ribulose 5-phosphate = (2S)-2-hydroxy-3-oxobutyl phosphate + formate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18457"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="ChEBI" id="CHEBI:58830"/>
            <dbReference type="EC" id="4.1.99.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7 8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="7 8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="7 8">Binds 2 divalent metal cations per subunit. Magnesium or manganese.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 7 8">Cofactor biosynthesis; riboflavin biosynthesis; 2-hydroxy-3-oxobutyl phosphate from D-ribulose 5-phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7 8">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the DHBP synthase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.99.12" evidence="3 7 8"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304874.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000613"/>
    <dbReference type="EnsemblBacteria" id="EEZ39593">
        <property type="protein sequence ID" value="EEZ39593"/>
        <property type="gene ID" value="VDA_000613"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0108">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="900513at2"/>
    <dbReference type="UniPathway" id="UPA00275">
        <property type="reaction ID" value="UER00399"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008686">
        <property type="term" value="F:3,4-dihydroxy-2-butanone-4-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00180">
        <property type="entry name" value="RibB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017945">
        <property type="entry name" value="DHBP_synth_RibB-like_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000422">
        <property type="entry name" value="DHBP_synthase_RibB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00926">
        <property type="entry name" value="DHBP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55821">
        <property type="entry name" value="SSF55821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00506">
        <property type="entry name" value="ribB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 8" id="KW-0464">Manganese</keyword>
    <keyword evidence="6 7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 8" id="KW-0686">Riboflavin biosynthesis</keyword>
    <feature type="region of interest" description="D-ribulose 5-phosphate binding" evidence="7">
        <location>
            <begin position="37"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="D-ribulose 5-phosphate binding" evidence="7">
        <location>
            <begin position="150"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="38"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>D-ribulose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="site" description="Essential for catalytic activity" evidence="7">
        <location>
            <position position="136"/>
        </location>
    </feature>
    <feature type="site" description="Essential for catalytic activity" evidence="7">
        <location>
            <position position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ39593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="217" mass="23594" checksum="26FA00597F1A35C2" modified="2010-01-19" version="1">MNQSLLAQFGTPFKRVEIALNAIRQGKGVLVVDDEDRENEGDIIFSAETLTSQQMAIMIRECSGIVCLCLTEERTKQLELPMMVENNTSANQTGFTVTIEAAEGVTTGVSAADRVTTVKAAIADNAQPSDLNRPGHVFPLKANSNGVLGRRGHTEATIDLMRLAGLKPYGVLCELTNPDGTMARLPEVINFGEKFDMPVLTIEDLVAYRLNQQELVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2K6</accession>
    <name>D0Z2K6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ATP-dependent RNA helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">VDA_000657</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the DEAD box helicase family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000657"/>
    <dbReference type="EnsemblBacteria" id="EEZ39637">
        <property type="protein sequence ID" value="EEZ39637"/>
        <property type="gene ID" value="VDA_000657"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0513">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014013">
        <property type="entry name" value="Helic_SF1/SF2_ATP-bd_DinG/Rad3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51193">
        <property type="entry name" value="HELICASE_ATP_BIND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="1"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="14"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="217"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="374"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="395"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ39637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="430" mass="48994" checksum="70D834816A5F27ED" modified="2010-01-19" version="1">MAFDQATEIQRTAIPVAILGKDILASSKTGSGKTLAFLLPAMQRMYRSKPFTRRDPRVLILTPTRELAKQVFAQLKPLNAGTPYDAALIVGGENFNDQVKALRKDPMFVVATPGRLADHLEHRSTYLDGLEMLILDEADRMLDLGFEKELRRIHEAASHRRRQTLMFSATLDHPEVVEMAHEMLNAPKRISIGHSAEEHKDITQRFILCDNLTHKEALLNKILETEDYNQMIIFTATRADTDRLTKELNDRKLKAVALSGNLNQTQRNSIMSQFERFCHKILVTTDIASRGLDISNVSHVINFDLPKHAEEYVHRVGRTGRAGNKGDAISFVGPKDWKSFKNIEAFLQQSIEFTAIDGLKAKFKGFKIEQKKKFNKKPTEQNNQKKKTQAAKPKRHIDKRFYDNQAVGHEVFMPKKKPRNVAAEIDKDQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2L8</accession>
    <name>D0Z2L8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000669</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305007.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000669"/>
    <dbReference type="EnsemblBacteria" id="EEZ39649">
        <property type="protein sequence ID" value="EEZ39649"/>
        <property type="gene ID" value="VDA_000669"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502Z7QS">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1378085at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003020012" evidence="1">
        <location>
            <begin position="36"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="359" mass="42273" checksum="AA2E8F6AF6A1F310" modified="2010-01-19" version="1">MVYGDHTTLRGNNKSRRQFWLSLPLCLIYSSANYAQPLSTEAEQDITIPEWVEVGQSTISEQVHDVSSYLDHSMAKDEDEEELINNSYLKIRLTPSYSYRDKFEFDTRASLKVDLPHTKQDWNLILETDPDDFDSLESKQRNTPTNGTSSFSEAVGGVRLQDLYFGSWKTNFDVGIKFRFPLDPFVRADIRRVDALSDNWTSRFKQELFYYHSKGPGSLTELDFYYAFKEDHSQIFKSASSAQYLENDDTWELVQTFTYFDRVSRRNLMEYSVGISSETDELKKVSNIWLSASWKRNLYKNWLYTTLTPQIEFPREHNHHINPGVWLELEILFSKNRKMDQLLRTIPTPYKKRIKDDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2P2</accession>
    <name>D0Z2P2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SAM-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000693</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305074.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000693"/>
    <dbReference type="EnsemblBacteria" id="EEZ39673">
        <property type="protein sequence ID" value="EEZ39673"/>
        <property type="gene ID" value="VDA_000693"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1515497at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="1">
        <location>
            <begin position="45"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="247" mass="28549" checksum="C25C354AAEA067E1" modified="2010-01-19" version="1">MSYNALYTDLSGYYDLMCADINYYEQSYNIRRIHQLFGNSGTKHLDLACGTGPHIEHLTSWGYQSWGLDINQPMLDMAQIRCPNANFTLQNMCDFKLDEPQDLITCFLYSIHYNDGIEKLKECIASVHAALNDNGMFCFNAVDKTKIDNRSFMRHSAEFENSNFTFQSGWNYCGEGERQSLQLSIEKTTEDVTEVWQDQHPMVAVSFPELKALLEPYFEVHILEHDYNKIIPWDKQSGNAIFACIKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2S1</accession>
    <name>D0Z2S1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">bPH_1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000722</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305159.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39702">
        <property type="protein sequence ID" value="EEZ39702"/>
        <property type="gene ID" value="VDA_000722"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG503172B">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1682253at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012544">
        <property type="entry name" value="PHb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037063">
        <property type="entry name" value="PHb_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08000">
        <property type="entry name" value="bPH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="bPH_1" evidence="1">
        <location>
            <begin position="2"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="126" mass="13945" checksum="4B5DD9DB2A3A1588" modified="2010-01-19" version="1">MGLFDALLGNAGAMDLNEATEDLAPILGPNETIELAYKLIRDMIVLTDNRLLLIDKQGLTGKKVEYRSIPYKSITMFTVESKGHFDMDAELKLWISGQHDPISLEFNGKTNIYTMQGLLAAKIAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2T5</accession>
    <name>D0Z2T5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Alpha-ribazole-5'-phosphate phosphatase</fullName>
            <ecNumber evidence="1">3.1.3.73</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000736</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.3.73" evidence="1"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305205.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000736"/>
    <dbReference type="EnsemblBacteria" id="EEZ39716">
        <property type="protein sequence ID" value="EEZ39716"/>
        <property type="gene ID" value="VDA_000736"/>
    </dbReference>
    <dbReference type="GeneID" id="57342754"/>
    <dbReference type="eggNOG" id="COG0406">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1122642at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043755">
        <property type="term" value="F:alpha-ribazole phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="210" mass="24558" checksum="D96A82B18C851A9C" modified="2010-01-19" version="1">MTIGETRVDFLRHGLPEGDKCLRGHTDFALTEVGFAQMEHAASSLKELDVIVTSPLQRCATFAHHIAQQFNLEVVEEPLWKEMNFGEWDGLEQQQLWQDIGPTIDSYWRDPWQLTEQGEALHKGETLEHFDARILQAWQTLVTQYAGKKILVVTHAGVMHQLLRHLLSMPKDTTYLHCIKFDYAARYRVTHFVDNENQQWPRLYWPPYID</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2V4</accession>
    <name>D0Z2V4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hypothetical nucleoprotein/polynucleotide-associated enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000755</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305258.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000755"/>
    <dbReference type="EnsemblBacteria" id="EEZ39735">
        <property type="protein sequence ID" value="EEZ39735"/>
        <property type="gene ID" value="VDA_000755"/>
    </dbReference>
    <dbReference type="GeneID" id="57343046"/>
    <dbReference type="eggNOG" id="COG3122">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1467864at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018636">
        <property type="entry name" value="DUF2058"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09831">
        <property type="entry name" value="DUF2058"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0543">Viral nucleoprotein</keyword>
    <keyword evidence="2" id="KW-0946">Virion</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="173" mass="19360" checksum="FDE95C34D59BDDC3" modified="2010-01-19" version="1">MAKLTLQEQMLKAGLVDKKKLKKAVKGSKKSRTQAKEAKAAVEANRQAQLEKDKQLNQQKNEAAQAKEIAAQVKQLIEMNCIDRKKGEEGYNFTDGSTVKTLYVTPELRDQLIKGRLAIARLGEGYELIPAVVADKIAQRDQESIVVNNTVDETVVDEDDPYADFVIPDDLMW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2X1</accession>
    <name>D0Z2X1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Maltose/maltodextrin ABC transporter permease protein MalG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_000772</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305300.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000772"/>
    <dbReference type="EnsemblBacteria" id="EEZ39752">
        <property type="protein sequence ID" value="EEZ39752"/>
        <property type="gene ID" value="VDA_000772"/>
    </dbReference>
    <dbReference type="GeneID" id="57343069"/>
    <dbReference type="eggNOG" id="COG3833">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1510342at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="91"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="120"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="163"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="202"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="258"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="85"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ39752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="296" mass="32048" checksum="0F65E8A5B8B3856D" modified="2010-01-19" version="1">MAMVQPQSLKYRVWATHIGMWCFLALMMFPLLMVIAISFREGNYASGELIPSNPSLEHWKLALGIAVQNADGTVTPPPFPVLTWLWNSIKVAGLTAIGIVTLSTTCAYAFARMKFAGKTLILRSMLIFQMFPAVLALVALYALFDRLGAYVPFLGMNTHGGVIFAYMGGIALHVWTIKGYFESIDGSLEEAAALDGATPWQAFRMVLLPLSVPILAVVFILSFIAAVTEVPVASLLLRDVGSYTLAVGMQQYLYPQNYLWGDFAAAAVLSALPITIVFLLAQKFLVGGLTAGGVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z363</accession>
    <name>D0Z363_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Exoribonuclease 2</fullName>
            <ecNumber evidence="7">3.1.13.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Exoribonuclease II</fullName>
            <shortName evidence="7">RNase II</shortName>
            <shortName evidence="7">Ribonuclease II</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rnb</name>
        <name evidence="11" type="ORF">VDA_000864</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates.</text>
            <dbReference type="EC" id="3.1.13.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the RNR ribonuclease family. RNase II subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.13.1" evidence="7"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305565.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000864"/>
    <dbReference type="EnsemblBacteria" id="EEZ39844">
        <property type="protein sequence ID" value="EEZ39844"/>
        <property type="gene ID" value="VDA_000864"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4776">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1602988at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008859">
        <property type="term" value="F:exoribonuclease II activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006402">
        <property type="term" value="P:mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01036">
        <property type="entry name" value="RNase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011129">
        <property type="entry name" value="CSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040476">
        <property type="entry name" value="CSD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013223">
        <property type="entry name" value="RNase_B_OB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011804">
        <property type="entry name" value="RNase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001900">
        <property type="entry name" value="RNase_II/R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022966">
        <property type="entry name" value="RNase_II/R_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004476">
        <property type="entry name" value="RNase_II/RNase_R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17876">
        <property type="entry name" value="CSD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08206">
        <property type="entry name" value="OB_RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00773">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00357">
        <property type="entry name" value="CSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00955">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00358">
        <property type="entry name" value="3_prime_RNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02062">
        <property type="entry name" value="RNase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01175">
        <property type="entry name" value="RIBONUCLEASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="5 7 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 7" id="KW-0540">Nuclease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="CSP" evidence="9">
        <location>
            <begin position="23"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="RNB" evidence="10">
        <location>
            <begin position="192"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="domain" description="S1" evidence="8">
        <location>
            <begin position="564"/>
            <end position="648"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ39844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="667" mass="75719" checksum="C331AF19BB5730F6" modified="2010-01-19" version="1">MFQDNPLLAQLKKQIQDTLTKKEGNVKATDKGFGFLEVDSKESYFIPPNYMKNVMHGDRVMAIIRTEKEREVAEPQELIEASLTRFIGRIKLIRDRMHVVPDHPQLKDAIRAKAAKGVNPETLKEGDWVVAKITRHPLVGDNKTFFCEVSEKITDSNDKIAPWWVTLAHHDLPNAEPAPQDSWNMIDEGLERQDLTELPFITIDGDSTKDMDDALYTVQKDDGSFEITIAIADPTSYISVGDKMDDEARERGFTIYLPGRNIPMLPRELSDELCSLIEGEKRPAICCQVTVNAQGEIQDDISFFAAWIQSQGRLSYDNVSDYLENGHCDNWQPTPVIEEQIKALHAFANARTEWRQNNAVIFPDRPDYRFELSADNDVVAIHTDFRRTANRMIEEAMITANICAGRVLSDKFGTGVFNLHSGFNLEKLDTAMEFLTKAEAPFSKEEVISLEGFSALRRWLNQQESSYLDNRLRKFQAYSEVGNKPGPHYAMGLDVYATWTSPIRKYGDMINHRLLKSVITGNPSTQTPDDNVGEEIAIHRRLHRMAERDVADWLYVRLLKDAVKKETVFTAEVFDINRAGIRARLLENGATVFIPAPLIIDNKERIQCSGELGTISIDGTEEYKLGDTFDVKLAEIRSTTRQLIAKPVKTYPELKTTAQDNENQVEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z364</accession>
    <name>D0Z364_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hypothetical GGDEF family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000865</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000865"/>
    <dbReference type="EnsemblBacteria" id="EEZ39845">
        <property type="protein sequence ID" value="EEZ39845"/>
        <property type="gene ID" value="VDA_000865"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2199">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="164"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="195"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="2">
        <location>
            <begin position="262"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="433" mass="48811" checksum="E83836E75BFD0689" modified="2010-01-19" version="1">MFSLSMLRNASIRLLIPLLIAGLLIFIYPQLYVLLTPFQASLQVLPFVVLALVIILSQPFNQGRIGIIAILMLESYFLILNCLQQPLASGDTRLIYILLSALLPLNLLLLHIVPEKRFLSRCGFAMLIFNMVQIALSVAIVWLYDGSALSDWWYAVFYSYNNISPLPIILLLLNIALICSSASAILKRNQRTDQAIYICLLFSFITLAWFDNPFISSMSYSCAAILLLSSLITSTHELVYIDPLTTIPGRRALDTELKYLGRTYTLAMMDVDNFKDFNDLYGHETGDEVLRLVAQISQKISGVGKVFRYGGEEFTLLFKGKNINEVQSQLEYVREEIACYDLVLRDHDNRPLSALQGKLKRQHNDLEPNAVHITVSIGAADSYSAPTPNDVLNLADIALYNAKDDGRNQVSVDYTLRKTKKKKRTPKKKKATK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z389</accession>
    <name>D0Z389_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein translocase subunit SecD</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">secD</name>
        <name evidence="11" type="ORF">VDA_000890</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the SecD/SecF family. SecD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000890"/>
    <dbReference type="EnsemblBacteria" id="EEZ39870">
        <property type="protein sequence ID" value="EEZ39870"/>
        <property type="gene ID" value="VDA_000890"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0342">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015450">
        <property type="term" value="F:protein-transporting ATPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043952">
        <property type="term" value="P:protein transport by the Sec complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01463_B">
        <property type="entry name" value="SecD_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005791">
        <property type="entry name" value="SecD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027398">
        <property type="entry name" value="SecD-TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022813">
        <property type="entry name" value="SecD/SecF_arch_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022645">
        <property type="entry name" value="SecD/SecF_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30081">
        <property type="entry name" value="PTHR30081"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13721">
        <property type="entry name" value="SecD-TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02355">
        <property type="entry name" value="SecD_SecF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00916">
        <property type="entry name" value="2A0604s01"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01129">
        <property type="entry name" value="secD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="425"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="451"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="479"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="518"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="549"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="domain" description="SecD-TM1" evidence="10">
        <location>
            <begin position="2"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ39870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="587" mass="63821" checksum="D5FACD01153ED04F" modified="2010-01-19" version="1">MVVTVAIMLLSAIPTWFGEDAAVQISAKGGPVPTPFAIKKELDDNHIAIKKIEQKPAHTIVILDEEDQQTKAKEVLAKLIKGENAEERLTLALEPAAPMWLQDMGFEPIKLGLDLRGGVQFLLDVDVNQVFKVQGQSLADDLRADFRKEGIRAARIEIMAADKLLVRLPSSDANSKIRHFVEQQYPQWQPTNGNGDNLILTLKEKEQTELRNLTVQQNLQTMRSRIEELGITEAVVQRQGENRIRIELPGVQDPAAAKKVIGATASLAFYAVKQEGTGSTMVLDDKQGRPVRVGRKPVLSGDHIIDARAGFGEMSTPEVNITLDSAGGHIMSEFSRHNIGKPMATSYSEYSRNDKGETVQTNTIISVATIQSQLGSRFRITGAGSLEDAQQLALLLRAGSLTAPVTIVEERTIGPTLGAENIKNGFAALALGMGVTLLFMAVWYRRLGWVANIALICNMIMLFGLLALIPGAVLTLPGIAGLVLTVGMAVDTNVLIFERIKDKLKEGRSFAQAIDRGFSSAFSTIFDANFTTMITAVVLYAIGNGPIQGFALTLGLGLLTSMFTGIFASRAIINLVWGRDSRHDVRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z399</accession>
    <name>D0Z399_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized phage-encoded protein-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305671.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39880">
        <property type="protein sequence ID" value="EEZ39880"/>
        <property type="gene ID" value="VDA_000900"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3646">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="890747at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014054">
        <property type="entry name" value="Phage_regulatory_Rha"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09669">
        <property type="entry name" value="Phage_pRha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02681">
        <property type="entry name" value="phage_pRha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="198" mass="22283" checksum="29EB4711A338D5B2" modified="2010-01-19" version="1">MPSQNVLSIAQLSPSDLVFLSPDNDLVTDSMSISKHFHKQHKDILRKIETLDCSEIFTSAHFYAHVRKLDIGNNAIRDSKYYQMTKDGFMFLVMGFTGKRAAVIKEAYITAFNLMAEQLKKQSAFLPCHRTLTVFENGQPIESKLVPNDAFIISKSKLPSLLQEGNVFTVDELLEIANSANRKIAELAKIHGKPLVQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3A1</accession>
    <name>D0Z3A1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000902</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39882">
        <property type="protein sequence ID" value="EEZ39882"/>
        <property type="gene ID" value="VDA_000902"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG50337FG">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="31"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="62" mass="6915" checksum="31B5068235BDD018" modified="2010-01-19" version="1">MMGLAAGAAVAYLLTNKKFQQGVANTGEKAWSAVRGEVEELKERLEDTQAELEYYRNLHKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-06-02" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3B8</accession>
    <name>D0Z3B8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000919</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305720.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000919"/>
    <dbReference type="EnsemblBacteria" id="EEZ39899">
        <property type="protein sequence ID" value="EEZ39899"/>
        <property type="gene ID" value="VDA_000919"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031Y6M">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1761229at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="25"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="94"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="26"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="45"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="335" mass="37154" checksum="E469B0BE9E084554" modified="2010-01-19" version="1">MAIEITGYETLDELEAMLDQLEDATVVDEPQTSVEEQPEVVSDSSESTVEERSDGDKDAASPTADQDDTVPSDEGTDEPKKVIIAKDGVHTIPYDVLEAERREAERLRQQLAEMESKQVEYENQARLLDIRDKQLQKLGVNPDDLPENLKVSEQQIDELRENYPELAPFITSLMAKVDAVSTSVSTAQSSTLEHNPIMADIRANTDLNSWMEEKGDKWSLALDIDDRLLADPKWSSKSQPERFNEVVRRTKAAFGENIPEAKPVATNKEIQEEAADKEQTVTNSLPASPSLVGASNTHEGSVLQQAANMNNEQLQVLMAGMTADQIDALLDQIDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3C1</accession>
    <name>D0Z3C1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative bacteriophage terminase large subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000922</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305725.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000922"/>
    <dbReference type="EnsemblBacteria" id="EEZ39902">
        <property type="protein sequence ID" value="EEZ39902"/>
        <property type="gene ID" value="VDA_000922"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4626">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="892377at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="535"/>
            <end position="554"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="554" mass="63342" checksum="54B1BE10DAF42338" modified="2010-01-19" version="1">MNNPENIAYIKARVGNKWWRLNNLYKIENEDGQLVTFKLRPAQALLFKMMGRKNIILKARQLGFSSAIDIYLLDEALWHKNLKCGIIAQDQGAAGEIFRTKIEIPFDNLPIWLKAEFPIESRRSGANGGYILFKNGSSIQCATSFRSGTVQRLHISEHGKICAKYPQKAKEVKTGTLNTIHQKAICFIESTAEGVGGDFHSMCVRSLDLFNSGEVIGDMDYRFHFFAWFQDPKYAAALPKSGLQLSKHHQEYFAAVEAAMNVILTDEQKQWYINKEIEQGEEIKQEFPSTPQEAFLTSGRRVFDAIKVMNAEAYTCKPLIIYDVEPVMGKKTKAQSMRNAENEMLQRSLLNMLLVWELPDMEEDYAIGVDIAEGLEHNDRSSFDIVKRSTGEQVAHWFGYLDTELFASLVRHIGLMYNTAFVGPERNNHGHAFIQAFRDIYPVRRIYQEQYIDRDNNNDTPKLGWLTTKQSKPIIIEGLKELLRTQSSGVRWIGTISELNSYVYDAKGSMNAQAGCFDDQVMSYAIAQEMRARMPATVKRKQNNHRASNHWMTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3C3</accession>
    <name>D0Z3C3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">Lysozyme</fullName>
            <ecNumber evidence="2 6">3.2.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_000924</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>Hydrolysis of (1-&gt;4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.17"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the glycosyl hydrolase 24 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.17" evidence="2 6"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305731.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39904">
        <property type="protein sequence ID" value="EEZ39904"/>
        <property type="gene ID" value="VDA_000924"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3772">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1703032at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003796">
        <property type="term" value="F:lysozyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016998">
        <property type="term" value="P:cell wall macromolecule catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019835">
        <property type="term" value="P:cytolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042742">
        <property type="term" value="P:defense response to bacterium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009253">
        <property type="term" value="P:peptidoglycan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.530.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_04110">
        <property type="entry name" value="ENDOLYSIN_T4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034690">
        <property type="entry name" value="Endolysin_T4_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002196">
        <property type="entry name" value="Glyco_hydro_24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023347">
        <property type="entry name" value="Lysozyme_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00959">
        <property type="entry name" value="Phage_lysozyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0929">Antimicrobial</keyword>
    <keyword evidence="4 6" id="KW-0081">Bacteriolytic enzyme</keyword>
    <keyword evidence="6 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 6 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="181" mass="20404" checksum="4B980B3BA0C0D7B1" modified="2010-01-19" version="1">MRYNKLTAKILAGAIALTGGFEGYRHYAYQDSGGVWTACFGETERIHPGDQFTISECETMLATSLDKHNAPIRKIPQQLPLSVHLAALDMSYNIGISAFEHSTMYRYLLNGDYPSACRQISRWRFVAGKDCAIKRNNCYGIVKRRELVQKLCLGKITINDALIQIGQEPLDEDILRQMNAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3I3</accession>
    <name>D0Z3I3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Hydrogenase maturation factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000984</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the HypD family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305908.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000984"/>
    <dbReference type="EnsemblBacteria" id="EEZ39964">
        <property type="protein sequence ID" value="EEZ39964"/>
        <property type="gene ID" value="VDA_000984"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0409">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="666873at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11750">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002780">
        <property type="entry name" value="Hyd_form_HypD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042243">
        <property type="entry name" value="HypD_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042244">
        <property type="entry name" value="HypD_2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30149">
        <property type="entry name" value="PTHR30149"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01924">
        <property type="entry name" value="HypD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005622">
        <property type="entry name" value="Hydrgn_mat_hypD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00075">
        <property type="entry name" value="hypD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR005622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="374" mass="41169" checksum="054E2D63AB411E78" modified="2010-01-19" version="1">MAVSTQLYQGFRQPDLVKALAEKIAQRAQLLTKPLYMMEVCGGHTHTIMKFGLKQLLPDNLHFVHGPGCPVCVMPKERIDQAIELAQQPDVILVTLGDMIRVPGSKSSLAQCRAQGGLVEPIYDPMDTLKIAKENPDKKVVFFAIGFETTTPMTAVLVEMAEAQQINNLYFHINHVLVTPAMEVILADGQSPINAFIGPSHVSAVTGSKIYQSVVDKHHIPLVVAGFEPADVLESVLMLVEQGIKEQALLDVQYKRVVTQAGNTAAQSLVERVFDVRDEFNWRGLGPIPHSALQLKPCYQHRDAEIIFDDCFSHIDTPDHKVCRCGDILKGLATPPDCKVFGKTCNPNRPMGSCMVSSEGACNAYYRYAGTEDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3I9</accession>
    <name>D0Z3I9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aspartate aminotransferase</fullName>
            <ecNumber evidence="2">2.6.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000990</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.6.1.1" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305925.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000990"/>
    <dbReference type="EnsemblBacteria" id="EEZ39970">
        <property type="protein sequence ID" value="EEZ39970"/>
        <property type="gene ID" value="VDA_000990"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1168">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1462898at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004069">
        <property type="term" value="F:L-aspartate:2-oxoglutarate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027619">
        <property type="entry name" value="C_S_lyase_PatB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04350">
        <property type="entry name" value="C_S_lyase_PatB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="1">
        <location>
            <begin position="63"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="389" mass="44619" checksum="F5896AE6B2AD5091" modified="2010-01-19" version="1">MAHELDTIINRYGTDCLKWDYMEKWLGVPEGEALPSWVSDWDFKAPNFITDALQERLNHGIFGYSERGDEYFNSVIDWWAERHQVSLQKEWFHTTPGSLPAIAMLVEQWCQVGDKVLVLSPVYHAFYRTIENTGRTVAESSLINDNGYYTIDFADLEAQFQNGVKIMIFCNPHNPGGRVWTEQEVTQVCQLCHQYGVYLISDEIWADMVFSGHTFYSCLRVEPQYFDKLAVCIAGTKTFGLPSMRLTNTMIPNEKEAQALKTKLLAYGIDVYSAFSIIANQAAYRNGHAWVDETVKYLEENNKILEAFVRDELKQVTYRVQESTYLAWLDCRAMGLDDQELEQKLHQAGVIPTMGYGFGRDGSGFIRLNLGCPKSILEEKISRLRTVLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3L4</accession>
    <name>D0Z3L4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Multidrug export protein MepA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Multidrug resistance protein NorM</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Na(+)/drug antiporter</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_001015</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305993.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001015"/>
    <dbReference type="EnsemblBacteria" id="EEZ39995">
        <property type="protein sequence ID" value="EEZ39995"/>
        <property type="gene ID" value="VDA_001015"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0534">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="216729at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13143">
        <property type="entry name" value="MATE_MepA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045070">
        <property type="entry name" value="MATE_MepA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006603">
        <property type="entry name" value="DinF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="56"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="93"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="139"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="164"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="191"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="238"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="270"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="316"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="360"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="389"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="416"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00030855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="457" mass="50044" checksum="A200E30A06846C5B" modified="2010-01-19" version="1">MHAQHIEQSASIGKTFVRYTIPAVTAMLVSGLYQIIDGIFVGHYVGYEGLAGINMAWPIVFILSGFGLMLGMGAGSLISIARGENKQQEGQKALLSSFHLMVILALLTLALLSAFAPVMLLAQGATITTMSLGLDYIDVFTWCSLITIMASAMPMLIRNDESPAIATGLMILGALLNIAFDYIFIGHFNMALQGAAIATILAQLCVCLGGIYYFLSKHSQLKLNIEWHKIDPATMKQVVSLGSSSLVMYLYASFVVALHNYQFMQYGSSMTVGAYAIVGYLMTLYYLLAEGIAEGMQPPVSYYYGSKQANKIKKMFVLALKCTLIAGISWVLLLNIFPETMIGLFNNNNSLLLAETTKGIQLHLFGLFLDGFIVLASVYFMSVNQAGKALTISVSNMLIQLPFLYLLPKWLGVDGVWMAVPLSNIALTAIVAPMVWKDIQHRSKDWNKANTLRFTHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3Y1</accession>
    <name>D0Z3Y1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PNPLA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001134</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001134"/>
    <dbReference type="EnsemblBacteria" id="EEZ40112">
        <property type="protein sequence ID" value="EEZ40112"/>
        <property type="gene ID" value="VDA_001134"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1752">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4775">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019867">
        <property type="term" value="C:outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010827">
        <property type="entry name" value="BamA/TamA_POTRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07244">
        <property type="entry name" value="POTRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="1 2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003020064" description="PNPLA domain-containing protein" evidence="3">
        <location>
            <begin position="27"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="domain" description="PNPLA" evidence="4">
        <location>
            <begin position="41"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXGXXG" evidence="2">
        <location>
            <begin position="45"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="2">
        <location>
            <begin position="72"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DGA/G" evidence="2">
        <location>
            <begin position="221"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="74"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="756" mass="84168" checksum="81998BA7739A1342" modified="2010-01-19" version="1">MSRLDRMHVRKGLLIVALCFSSNIFADAIDRPQIDRKKVGLVLSGGGAKGAAHIGVLEVLEENRIPVDVITGTSMGAYVGGMYAMGLTAKEVKDRTLNANWDQGYNDRAKRNDLTLRRKQQNDDFQLHTDLGLDLNGEFKARPSAFQGQGMAVLLRNLTNNLPAVSSFDQLPIPYRSVATDIANVAPYVISSGHLATAMQASMTVPGALKPVKLNGKLLVDGGVVNNMPVDIAQKLGADVIIAVDLRDSLLPQKDLESALNIISQLTTYMTNASADHQKSLLHPGDIYMQPDVSFMLAPDFDKMDLAYRAGRNIANKMLPALLKFQVSPAQYEQYLKEKQNRRSQLAAHSAYYIDTIDIDNHTRLSDTALLALLDLKTKRIISNEELEEAVNRLQSQDIFAKVGYEIEHRSGKNVLVMKVDEKPWGPGYLNFKLTFEDDFSERSDFTFGAQYIYTDVTDKGGEWTVEAQLGSWKKVNTELYLPFDYDQKFFSAFGASWNNEIRQFSNIDADASSLNLRAEYANYTGFAELGWNVRPWAVFNMGYRIQDGKIRLLVNGTKEDYRTYGPYWSFTYDDLDNFYFPSKGTYFSSEFGLIDAKTAFLGESESGYGSYYDVSLIQPWNLGRHSVVSILKSGGSDSEEILPINVQDLGGLFNLSGYHRYELNGRYSAFAGLVYRYRLFDNDFGAFSSPVYLGGSIERGGVWNHMSDMSWNSAISAGSVFIAIDSFLGPVYFGYGQSSHGDNSIYLSVGGGIQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3Y6</accession>
    <name>D0Z3Y6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Probable phosphatase VDA_001139</fullName>
            <ecNumber evidence="4">3.1.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_001139</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="4">Binds 3 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PHP family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.-" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306319.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001139"/>
    <dbReference type="EnsemblBacteria" id="EEZ40117">
        <property type="protein sequence ID" value="EEZ40117"/>
        <property type="gene ID" value="VDA_001139"/>
    </dbReference>
    <dbReference type="GeneID" id="57343393"/>
    <dbReference type="eggNOG" id="COG1387">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1615112at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01561">
        <property type="entry name" value="YcdX_phosphat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023710">
        <property type="entry name" value="Phosphatase_YcdX_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004013">
        <property type="entry name" value="PHP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003141">
        <property type="entry name" value="Pol/His_phosphatase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016195">
        <property type="entry name" value="Pol/histidinol_Pase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02811">
        <property type="entry name" value="PHP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00481">
        <property type="entry name" value="POLIIIAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89550">
        <property type="entry name" value="SSF89550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="POLIIIAc" evidence="5">
        <location>
            <begin position="5"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="16"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="74"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="248" mass="27261" checksum="E6219E6FD09113D5" modified="2010-01-19" version="1">MQILVDTHTHTVSSGHAYSTLLENAEFAAKNGLKMFCTTDHAPSMPGAPHFWFFANQRILPRFLHNVAIIRGVEANILNQEGDIDLDQRIIDSLDWVIGSFHEPIFQPADKASHTQALINAISSGNIDAVGHPGNPHFDFDFEMVLRQAANHNVAIEVNNSSLGGSRVGSAPRCSDIIAMAKELDVFITTGSDAHFAADVGNFTQVKALLKHHNFPQERVITNSPDSFLSFLELRGKEPISEFSVNSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z407</accession>
    <name>D0Z407_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Luciferase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001160</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306376.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001160"/>
    <dbReference type="EnsemblBacteria" id="EEZ40138">
        <property type="protein sequence ID" value="EEZ40138"/>
        <property type="gene ID" value="VDA_001160"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2141">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1434838at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011251">
        <property type="entry name" value="Luciferase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036661">
        <property type="entry name" value="Luciferase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00296">
        <property type="entry name" value="Bac_luciferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51679">
        <property type="entry name" value="SSF51679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bac_luciferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="343" mass="39078" checksum="5CDFDD7A53EE051D" modified="2010-01-19" version="1">MKISLCLHIEKNAHTDSYQQAYNEFITLCKMADRAGFHTLWTGEHHGMDFAITPNPLLSLADLAHQTQSIRLGTATLIAPFWHPIRLAGEIAYTDMICHGRLEVGFSKGAFHYEYDRLKPGMNNDDAGEMMRESIQALQKLWQGNYSHQGKHWQFPETSISPQPSQLPHPPLWVAAQSPYTIDFAIEHGCNVQMTPLWFGEDKVQECINTYQHAVQKHQADHTKMLLLRHAFIVNSEEEKARILAEFSTFYAEFAAWFNQSNPVSNGNLVGDIEIGEMFTVETLAQNLLIGTAQEVLAQLKQYEAQGVDEFALWIANGMSFETKKVFLEQFIEHVLPHFQSNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-02-10" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z464</accession>
    <name>D0Z464_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase OrfAB subunit B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000320"/>
    <dbReference type="EnsemblBacteria" id="EEZ39302">
        <property type="protein sequence ID" value="EEZ39302"/>
        <property type="gene ID" value="VDA_000320"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2801">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032196">
        <property type="term" value="P:transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038965">
        <property type="entry name" value="InsF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46889:SF1">
        <property type="entry name" value="PTHR46889:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="1">
        <location>
            <begin position="52"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="225" mass="26215" checksum="DF076D2AD59811CD" modified="2010-01-19" version="1">MVTTQGIPLSRYRASKQMKAFNLVSCQSPKHRYRKANQEHIAIPNHLDRQFAVTSPNQVWVGDVTYVWAGNRWMYLAVVIDLFSRKPVGWAMSLSPDSRLTGKALMMAYESRHKPKGVMFHSDQGSHYTSSYYRQLLWRCQIKQSLSRRGNCWDNAPMERFFRSLKTEWVPNVGYCSFAEAKHEITRYIIGYYSQLRPHQYNGGLTPNESERLYWLTSNTVASIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4E7</accession>
    <name>D0Z4E7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000403</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304271.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000403"/>
    <dbReference type="EnsemblBacteria" id="EEZ39385">
        <property type="protein sequence ID" value="EEZ39385"/>
        <property type="gene ID" value="VDA_000403"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3179">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="169425at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="958" mass="108369" checksum="1DC41B79EA0A1952" modified="2010-01-19" version="1">MFLYPFNQKNGSPYPSQKAFESVLQKESVGHFGFNASNLCWHGGVHVSHNNAPWLKDESPLQAIADGVVVACRISDTYQHSRFEGQTLDYSSDFCLIQHTVANPKQSEETFTFYALYMHLAPLCSPHREVSEHPRYRLRTSQSAKILEVTGESVSLDKGTIIEATNEEIVKQNGYAFKPFTVIRTSSGQWVEKTVWLAVEKDGPPSDIRRRFLGDAEQYQALLHDNKAWIEPDLWQPPRSLKRGSRVKALSLEPVRSGDYLMHAYKLLDSEETVWFVTGKYESSSSFFDTYADSYQLPNWLLTKVIARTRTEGLCGRSDPKNNTQGELEAGAVAFHLPKDTLLRFDKTQDCSLQKLNGKMRLMARCQLDPTTPVKNSSGQLAREVWVCVEDEFIEVVQADTVALNSLHCFGTRSSLVISGGDAIGYLGRYDVANAEENKPPVTVRHQVHFELFSNEKPPQFFIDMYLGEADKENPYFVLSDISGCDGFLDLDEPSPFFQQLSAHTGKQGTSGFDILRNLMDWNSEKTVIAQHESEWAVKSSEKAFLPKLVEKVNKPRFTALIEHEKERIDNMIWLPEVSKLGLSNNVWNWWPIHYVESTDDVNDVYLVIMDEDISIEDFAQQTYHSKDKTVIDHILRTNPHLKRSFHQIVAGMPMVVSPYTYSHSGEADALSFADKLMTEFLTLNDEQKAWYGKNSALVNHTALMLPPSESGGIGWNDVVVGSTAAIASYQIIHDSFNNRLEQFAQFMDEANKELQYVDKANLKSHPKYKAYRQELKLLEQDLKGLFKQYWKPSYLKELQVPSINELFNIGNRQLYRTADFAESFSAINTAKVFKDAMKTSRMLGLAGDTAFLLGARNNIMNMWDSCDTNTLTEDCEKAFIKNGTSLVVNYQVGTSIMTYAVSLAPSSMGLSLVIGIGGTMLWGYYGGELTDSIGDVVEYMVFDLTIEDVKNKIKEFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4E9</accession>
    <name>D0Z4E9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">EamA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000405</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304275.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000405"/>
    <dbReference type="EnsemblBacteria" id="EEZ39387">
        <property type="protein sequence ID" value="EEZ39387"/>
        <property type="gene ID" value="VDA_000405"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0697">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1420919at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="145"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="177"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="207"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="234"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="259"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="10"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="298" mass="32276" checksum="582DF70E86EB5E4A" modified="2010-01-19" version="1">MNKNHSVGFAMLILIVGNLIAVFSDALVKTVGADSPVFQFVFFRQLTAVLMLLPFCYRYSLSSFTSGIKWHALRGHVWLLGAIGMFISLNTMPLATANAIFYAAPLLMLPLAMFIYNEKLTRYSLFAAICGFAGVLVVIRPTEISWSAIAALVVAVTLALNNLLIRKLPAEQTVIQTLFLTNLVGMPASLTLALLEGKPWDWGPLLTAAGSSALILIYAGSCVVAYRSAESSKIASAEYSGLIGAVGVGILWFNELPDIYMLIGTIMIVIPIAWLANVEKRKQKVLAAQTQPLEHVAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4H4</accession>
    <name>D0Z4H4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hypothetical cytosolic protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000432</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000432"/>
    <dbReference type="EnsemblBacteria" id="EEZ39412">
        <property type="protein sequence ID" value="EEZ39412"/>
        <property type="gene ID" value="VDA_000432"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1361">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3291">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3391">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4719">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1671219at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001434">
        <property type="entry name" value="DUF11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045474">
        <property type="entry name" value="GEVED"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20009">
        <property type="entry name" value="GEVED"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01451">
        <property type="entry name" value="B_ant_repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GEVED" evidence="2">
        <location>
            <begin position="478"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="domain" description="GEVED" evidence="2">
        <location>
            <begin position="1046"/>
            <end position="1120"/>
        </location>
    </feature>
    <feature type="domain" description="GEVED" evidence="2">
        <location>
            <begin position="1521"/>
            <end position="1599"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="418"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="422"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="1987" mass="208374" checksum="4D6E80917A59F4F2" modified="2010-01-19" version="1">MEDYLITVVAAQISGFVFNDDGSGGGAATNGIKDGSETGLGVAVPIVAYNTITGLCYAAISDATTGAYTITAGIAGTYKVYEAVNETNIASPTCPPTAPTLDTNTGSYVGGTIGDPSTFQSSSANIVTVSAGVVTNVNFGDFAVSSFDICSSAAYLTQSSGGVTQLNAVNLATGSIDLLTSPVTAGSAVGYSMVTNTLAGMQGTSTLNLFDSAYNTYSLSITNSTMPSGSNNGDIDDNGILYAHNGGTFYLFDTNPNSETYLTQVGTLPTTSLNYADIAFNPIDGFIYSVPSDGSRILYRFNPTTGVRTSLGLLSGIATGPYGAMYFDDQGYMYISENPSPGRIYRIDVLDGSKPAGSYTATLFSQTNASAAGNDGARCRYAPVPLDWADAPTVDGYATELTADGPRHQTDVGLPYLGGNTADNENDGQPTATANGDDTNGVTPDDEDGFTQPFIPTILVAGDTLSLTVPVVTSGSDNLYGWIDFDLDGVFDNDETATVTVNASGNSTLNFTVPADVQIMDTFARLRICSSGEVCAQPTGSAGDGEVEDHLISLKPPGDLALMLALDPSANVTLGIPFNVVVSVENMGATVALNTKVTLPIPAGYSFVKAYAGDGVTEITTYDPVTGELDLGAVGLGFNDYAVIRLAPQSLTAPAISAEIIETSINDIDSTPNNGFGNGEDDTDTVTPIISNTVQPGTCDAPRAFAAGNAYLDTNGEYVVTPNATNQYGFLWSYGFIDLNQPFYIELAVYLGDRSANVVPPFNIEAGGDGMTFVLSNDPRGLNAQGGLGGYLGVDGIGNANIFGSTETRIAPSMVVEFDTFDNTYIGATDDLDDGLGKLDHTAVYLHGDVYTPSAGNTLIAANPVNGGELEDGRYHITQFEWDPSTNTMMYYMDGVLVGSFTRDLIADLGGNLVRFGFTGSTGDAYNLQKGCFTAAPNVLGTDLGDAPDTTVGTGINNYTTTYENDGAMHVQADTDDNGFIDLRMGNLWDADLGNLQDIGAIADDNNNFDDEDGVTLVQSATKGENFDITVNVVEDSDRASTGQRLYAWLDFNLDGDWDDAGEQIVADTSAAIGNNSYSVPIPAGAVVGYSYLRVRLCSDVGCDSPIGLANDGEVEDYRVLISDLVGNNQCDLIMQTRLPVSATDYTYTSLDVPSNPITFTDIVNPITIVNQSNIANINALGFNRISGLIYGTFTDMSQADRIHHLFVTDKTGTSFIDLGEIRAESTTTIRRLQDGESFDFAAGDSLRHTGYSSTSTVLSSPTAGDVTADGNHLIVWRTSWDSLVKIDLNTQTFTTVPLDIATMGGSYGGGSIEVGADLAISSQSGLGYLVDLNGDNLYTVNLSTGAVTAQALAYFGAEPTLDTNGKLQAGALVMDNAVSLYALTNGGNHDTDNNGVIDLNERAVVYRINVMTQEVEYVTASDQGSLQGNDGAGCYDSTDYGDAAASYGQASHAYFDVAVDGTADLYLGARWDPEFGPWLSVDASGDDNYGQDDEDLVIPTQIIVETSTTLPIQVVGDGFVSIWVDLNNDGDFADSNEQLINDQAVTTGNNSISVILDAASAEGFNGNTVMRVRLCSSANSCNTFDGAANDGEVEDHWFELLNRIVLSGVVFEDNGVGGATAAHDGLQEGSEVGLGNFTVTVTFNDTGVTGFTPGDVIATDLTSGDGSYQFVIGVDFSGKDLLLDVVKQADWIDISEADVTGITQVTSSSVTDSQMSVNANAGDDISGLDFGKVQEPRMEPDNFSEAEPGKSVLFSHKFTAATAGSVNFSIINTEVEPVNDGWNAVLYQDNDCNGVIDGADTQIVNPVAVSGNTAVCLLSKVFVPADAPLNALYHYDIAADMTFADSAATGHGVTRQVLDKDTVRATFSGAGELKLEKTVRNITQGTAVGVSNQGRPGDVLEYTITFTNVGSGDLTEVSIFDSTPSYTELSQAIDCTSGSVPTSLICIPVTANGTNTVGYEGEVRWDMTGSLLAGEQGTVIYRVVID</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4M6</accession>
    <name>D0Z4M6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000484</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304493.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000484"/>
    <dbReference type="EnsemblBacteria" id="EEZ39464">
        <property type="protein sequence ID" value="EEZ39464"/>
        <property type="gene ID" value="VDA_000484"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="8"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="300" mass="34886" checksum="A888E5942BCD97CD" modified="2010-01-19" version="1">MVRDINKLDLKVLHLFKVIVDCGGFSQAQEKLGTQQSTISTNMASLERQLGMTLCQRGRKGFKLTLEGEKFYQFVETLFTHIRDFEVNIQELQMQSQGYIRFAMIDCVVTNPDCLLTRALERLRQEFPLAKIDSRVEDTLKIEELLLAKELDIAITSSEIRRDGLEYIEIFSEYQSLYCRAEHPILKQKQPLTLDFLKRYAIVDRATEHKITPVRDFGCEVFAYTSNMEMTALLLLSSDYIGHLPEHFAELWVQRGELIKLDIPNTDYKTEFHLTQRKDVTHPDAVAYLVEQLKDVHAFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4Q6</accession>
    <name>D0Z4Q6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">D-ribose pyranase</fullName>
            <ecNumber evidence="2">5.4.99.62</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_000514</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>beta-D-ribopyranose = beta-D-ribofuranose</text>
            <dbReference type="Rhea" id="RHEA:25432"/>
            <dbReference type="ChEBI" id="CHEBI:27476"/>
            <dbReference type="ChEBI" id="CHEBI:47002"/>
            <dbReference type="EC" id="5.4.99.62"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="5.4.99.62" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000514"/>
    <dbReference type="EnsemblBacteria" id="EEZ39494">
        <property type="protein sequence ID" value="EEZ39494"/>
        <property type="gene ID" value="VDA_000514"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1869">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0062193">
        <property type="term" value="F:D-ribose pyranase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016872">
        <property type="term" value="F:intramolecular lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048029">
        <property type="term" value="F:monosaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005996">
        <property type="term" value="P:monosaccharide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1650.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023064">
        <property type="entry name" value="D-ribose_pyranase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023750">
        <property type="entry name" value="RbsD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007721">
        <property type="entry name" value="RbsD_FucU"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37831">
        <property type="entry name" value="PTHR37831"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05025">
        <property type="entry name" value="RbsD_FucU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102546">
        <property type="entry name" value="SSF102546"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="78" mass="8665" checksum="B0636A61D4BB4BCD" modified="2010-01-19" version="1">MQIEGVVLAQELPQINPTVHEALIALIREEEALCGKQIKVNYISHEAFKLQTHESKAVVRSGECTPYANVIFQSGVVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4Z4</accession>
    <name>D0Z4Z4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Site-specific recombinase resolvase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_000227</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306664.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000227"/>
    <dbReference type="EnsemblBacteria" id="EEZ39211">
        <property type="protein sequence ID" value="EEZ39211"/>
        <property type="gene ID" value="VDA_000227"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1961">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1791095at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000150">
        <property type="term" value="F:DNA strand exchange activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006118">
        <property type="entry name" value="Recombinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006119">
        <property type="entry name" value="Resolv_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036162">
        <property type="entry name" value="Resolvase-like_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00239">
        <property type="entry name" value="Resolvase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00857">
        <property type="entry name" value="Resolvase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53041">
        <property type="entry name" value="SSF53041"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00397">
        <property type="entry name" value="RECOMBINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00398">
        <property type="entry name" value="RECOMBINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51736">
        <property type="entry name" value="RECOMBINASES_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0229">DNA integration</keyword>
    <keyword evidence="3" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Resolvase/invertase-type recombinase catalytic" evidence="6">
        <location>
            <begin position="2"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-serine intermediate" evidence="4 5">
        <location>
            <position position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR606118-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="209" mass="24046" checksum="03CF56FC855BD685" modified="2010-01-19" version="1">MYIFGYLRASTSDQNAKRAQSTLKSFVQDKGYRVAGWYIENESGASLQRPELLRLLDDAAIGDAILIEQIDRLSRLNEASWFKLKEMLHEKELKVISLDLPTSHIALSPQITDEFTGSMIKAINNMMMDMLAAIARKDYQDRRRRQAEGIKKAKSEGKYKGRRPNLELHDKIYQLRVVNRLSISDTAKLTNVSNRTVIRVAKKFIRENN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4Z8</accession>
    <name>D0Z4Z8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">Ribonucleoside-diphosphate reductase</fullName>
            <ecNumber evidence="4 12">1.17.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">VDA_000231</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>[thioredoxin]-disulfide + a 2'-deoxyribonucleoside 5'-diphosphate + H2O = [thioredoxin]-dithiol + a ribonucleoside 5'-diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23252"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:73316"/>
            <dbReference type="EC" id="1.17.4.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 12">Genetic information processing; DNA replication.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the ribonucleoside diphosphate reductase large chain family.</text>
    </comment>
    <dbReference type="EC" id="1.17.4.1" evidence="4 12"/>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000231"/>
    <dbReference type="EnsemblBacteria" id="EEZ39215">
        <property type="protein sequence ID" value="EEZ39215"/>
        <property type="gene ID" value="VDA_000231"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0209">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00326"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004748">
        <property type="term" value="F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005144">
        <property type="entry name" value="ATP-cone_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013346">
        <property type="entry name" value="NrdE_NrdA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000788">
        <property type="entry name" value="RNR_lg_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013509">
        <property type="entry name" value="RNR_lsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008926">
        <property type="entry name" value="RNR_R1-su_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039718">
        <property type="entry name" value="Rrm1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11573">
        <property type="entry name" value="PTHR11573"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03477">
        <property type="entry name" value="ATP-cone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02867">
        <property type="entry name" value="Ribonuc_red_lgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00317">
        <property type="entry name" value="Ribonuc_red_lgN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01183">
        <property type="entry name" value="RIBORDTASEM1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48168">
        <property type="entry name" value="SSF48168"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02506">
        <property type="entry name" value="NrdE_NrdA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51161">
        <property type="entry name" value="ATP_CONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00089">
        <property type="entry name" value="RIBORED_LARGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6 12" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 12 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-cone" evidence="13">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEZ39215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="729" mass="81546" checksum="4F2F5B753EA8A53B" modified="2010-01-19" version="1">MLADGLKVEPIAVAQRVVSGLYDGIKVTEIDVFLAETAASLATEHPDYAKLAARVMVSSLQKETSGYATATRELSEIGILSSAYVDFVAKNQFALEDMIDYKRDYQFDYFGYKTLERSYLLKVKGVVVERPQDMFMRVAVAVAGDDLEEIRELYDLLSLCYYTHATPTLFNAGCKMQQLSSCFLLAMQEDSINGIYDTLKDCALISKSAGGIGLHIHNIRATGAPIIGTNGVSNGIVPMLKVFNETARYVDQGGGKRKGSFAVYLEPWHADIESFLDLRKNHGKEEFRARDLFLALWVPDLFMERVETDAEWTLFSPHNTKGLSDLYGAEFTQKYQEYERMGLGVKTIKARQLMTQIIESQAETGTPYMLYKDACNEKSNQKNLGTIKSSNLCAEIMEVSTPDETAACNLASLALPKFVTNTGFDFDKLHQVTKVAIKNLDRVIDVNYHPTDKIEKSNHAHRPVGLGIQGLADVFFKMHLPFDSEEALLLNRDIAETMYHASLEASCEIAKQKGTYSSYDGSPISHGQFQFDLWCEQPSSRWDWSQLKHQIAEHGVRNSLLIAQMPTASTAQILGNNEAFEAQTSNIYKRQTLSGEFIIINKYLVSDLEQRGLWTSKIRDAIILNNGSVQGIDAIPDDLQSVYRTVWEISQKVIIDMSAARAPFVCQSQSLNLWLASPTFAQINAMHFYAWKRGLKTGMYYLRSKPSTNAVKVTVGQQSEDEDCLNCGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z506</accession>
    <name>D0Z506_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000239</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000239"/>
    <dbReference type="EnsemblBacteria" id="EEZ39223">
        <property type="protein sequence ID" value="EEZ39223"/>
        <property type="gene ID" value="VDA_000239"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0517">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007069">
        <property type="entry name" value="Transposase_32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026889">
        <property type="entry name" value="Zn_Tnp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04986">
        <property type="entry name" value="Y2_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14319">
        <property type="entry name" value="Zn_Tnp_IS91"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn_Tnp_IS91" evidence="1">
        <location>
            <begin position="15"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="193" mass="22472" checksum="20D2D08A1EB2B74D" modified="2010-01-19" version="1">MHVPRATKLIFNKDEAWEKYLTHCGDNITTNQIECIEKMLACCTSKVGSKHYECENPSCEHRKVIYNSCKSKACSSCGVMLTEKWIAKQLSILPKCEYQHMTLTMPDKLWPIFRLNPWLINLLYRCAVSAFLSFAKKRGIEIGLFCVVHTFGRQLNWNVHFHLSVTRGGVNLKTKRWGNIYFNAAMVEQYWKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5B9</accession>
    <name>D0Z5B9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000026</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000005">
        <property type="protein sequence ID" value="EEZ39041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000026"/>
    <dbReference type="EnsemblBacteria" id="EEZ39041">
        <property type="protein sequence ID" value="EEZ39041"/>
        <property type="gene ID" value="VDA_000026"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0582">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007069">
        <property type="entry name" value="Transposase_32"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04986">
        <property type="entry name" value="Y2_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="323" mass="38409" checksum="4DC8CC2AF5B2AA31" modified="2010-01-19" version="1">MLTEKWIAKQLSILPKCEYQHMTLTMPDKLWPIFRLNPWLINLLYRCAVSAFLSFAKKRGIEIGLFRVVHTFGRQLNWNVHFHLSVTRGGVNLKTKRWGNIYFNAAMVEQRWKQQVVSLLRDHYNALNTKHDNYQHIRDFRGWSQFLSSQYSRKWRIHLAKKTEDVGPTVRYLGRYFKRPPIAASRLRHYQGGDVHFVYKDHRDNCYKTLILSQIEMIDRLVSHIPAEKNFRAIRYYGFLSNRKRGEALPLVYDLLDQEEPVEPKPLNYAQMMHHLVGIDPYKCILCGGRMCFVKMEMGLKGHELVALRKATIREKRRLRYSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5F0</accession>
    <name>D0Z5F0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000057</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000005">
        <property type="protein sequence ID" value="EEZ39072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005307098.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000005.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000057"/>
    <dbReference type="EnsemblBacteria" id="EEZ39072">
        <property type="protein sequence ID" value="EEZ39072"/>
        <property type="gene ID" value="VDA_000057"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG50310W8">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="213" mass="23302" checksum="058BED0DC26A70A3" modified="2010-01-19" version="1">MATNTNWLKCKTGPVVLTEGTNDCHVIVALCQAHSVPHEFGFYSCDSDNQAIQRFRLLLNGSDCPEKLAIVLDADAPNLASRWNCLSKILTSKGYQVPETPTPEGTILTDDNLPRVGVWLMPDNTVDGMLEDFCMKLAAEASFGEVQTFLDSAKQSGLANYKDVHNSKALIHCYLATQDEPGSPLGLAITKKVLSPDQPSAHIFTNWLKSVFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-06-02" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5I7</accession>
    <name>D0Z5I7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000005</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000007">
        <property type="protein sequence ID" value="EEZ38998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005307233.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000007.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ38998">
        <property type="protein sequence ID" value="EEZ38998"/>
        <property type="gene ID" value="VDA_000005"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ38998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="126" mass="14575" checksum="801EEE33036A137A" modified="2010-01-19" version="1">MSLLKKKSSLPEKREPLTTKSAVIEEQREQTREYQKRQRAKYADHWKAEKSVIDAISGNELNDYIVEHADDVTDNRCGIHSMKINPYELAVIKKAMEIEGSRSSRELFIDYCKSIIKGNTKSKDNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVL0</accession>
    <name>D0YVL0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001602</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298359.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001602"/>
    <dbReference type="EnsemblBacteria" id="EEZ40575">
        <property type="protein sequence ID" value="EEZ40575"/>
        <property type="gene ID" value="VDA_001602"/>
    </dbReference>
    <dbReference type="GeneID" id="57342321"/>
    <dbReference type="eggNOG" id="COG0700">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1757687at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011642">
        <property type="entry name" value="Gate_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07670">
        <property type="entry name" value="Gate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="Gate" evidence="2">
        <location>
            <begin position="29"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="153" mass="16004" checksum="4689983969C592DC" modified="2010-01-19" version="1">MTTAKKPMVTDIFVEGAKKGWVIATTSTVPNVLMAFVIIKALQITGALDAMGAIFSPVMAIFGLPGEAAAVLIGAWMSMGGAVGVVITLFDQGILNGQHIAILAPAIYLMGSQVQYMGRIMGPIGTEGRYIPVMIAISVLNAFAAMFVMNILV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVU4</accession>
    <name>D0YVU4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HrpA-like helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002025</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002025"/>
    <dbReference type="EnsemblBacteria" id="EEZ40993">
        <property type="protein sequence ID" value="EEZ40993"/>
        <property type="gene ID" value="VDA_002025"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1643">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04408">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="1">
        <location>
            <begin position="33"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="2">
        <location>
            <begin position="215"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="818" mass="92437" checksum="34CC2CDFCA394361" modified="2010-01-19" version="1">MSQYGNSLSLFVLFGLVRRMSFSLPIDAVKKEFLQQLSSHHLVVEAETGSGKSTRLPIWAAKDGKVLVVEPRRVACTSLAEFIAVTPDDENRIWGSKIGYAIRFDNQFDQDTDIVFVTPGVALRWLSENGLADFKTIIIDEFHERRWDTDLLLSLLLQTQSHRLVVTSATLDSQRLAEYMAAKRLTANGRMFDVEVIHQASDARSMPEIQHIERKIGQALEVHREHHQDILVFLPGRKEISSVKQSLQQKYRDDIEGGKLDVISLHASVSEQEKQRALTESEKQRIILATNVAETSLTIPGITLIIDSGLERRTHQRNGRTVLSLHAISNASAEQRKGRAGRVRSGTCIRLYGKAAPLERLTPPELLREELVEPYLAALCCGYSLESLPFIDVLPEKTLEQARSVLTKMKAIDDKGAITDHGRVLYPLPIDTLFAHLITAMPTRGLKEAMVDLSAALSVPQKLWQSPSGEEQLALLKQWLKIEGCDATGLIAIVRTPFDELPDWLNVDPLVHQEAQQLSVQIRDALELPELSVASRFKRAEWLDAVMVATPELVFVRRERRRQALTNGFYELTVGRDCLLLDDAEAAIVFDQYALPGRGVKQNLVLATCMAPVTLSLIKAHHLATEQVGETIQTDDGVRTSIDYVYAGRVIKSEWRQPEGDIAQEALVDLIISNQILDGLYTKLEFDIHQWNLYLALGLYDETQCQLPAKTVVTKDWLAQQIEDLGVETVDDLEMFTCDDFTFNGIPEWERSDFDERYPAVVALNDLKMTIEYHVASKMVTAVHCDGKRKQDPKRWELPRWNGWRVKYRKASRIIDIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVX5</accession>
    <name>D0YVX5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 11">L-aspartate oxidase</fullName>
            <ecNumber evidence="4 11">1.4.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">VDA_001256</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the oxidation of L-aspartate to iminoaspartate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-aspartate + O2 = H2O2 + iminosuccinate</text>
            <dbReference type="Rhea" id="RHEA:25876"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:77875"/>
            <dbReference type="EC" id="1.4.3.16"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:25877"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Cofactor biosynthesis; NAD(+) biosynthesis; iminoaspartate from L-aspartate (oxidase route): step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.16" evidence="4 11"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001256"/>
    <dbReference type="EnsemblBacteria" id="EEZ40234">
        <property type="protein sequence ID" value="EEZ40234"/>
        <property type="gene ID" value="VDA_001256"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0029">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00326"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008734">
        <property type="term" value="F:L-aspartate oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044318">
        <property type="term" value="F:L-aspartate:fumarate oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.700.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-binding_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037099">
        <property type="entry name" value="Fum_R/Succ_DH_flav-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015939">
        <property type="entry name" value="Fum_Rdtase/Succ_DH_flav-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005288">
        <property type="entry name" value="NadB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027477">
        <property type="entry name" value="Succ_DH/fumarate_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42716">
        <property type="entry name" value="PTHR42716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02910">
        <property type="entry name" value="Succ_DH_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46977">
        <property type="entry name" value="SSF46977"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56425">
        <property type="entry name" value="SSF56425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00551">
        <property type="entry name" value="nadB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11" id="KW-0274">FAD</keyword>
    <keyword evidence="6 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 11 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7 11" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_2" evidence="13">
        <location>
            <begin position="48"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="domain" description="Succ_DH_flav_C" evidence="14">
        <location>
            <begin position="481"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="493"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEZ40234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="576" mass="64267" checksum="C6E37AC0B2AAE46F" modified="2010-01-19" version="1">MHYGDSPSIHLLTITRICLIMTNSAQNGKQQPQGLGINMTDTPQHQCDVLVIGSGAAGLSLALRLASIGNITVLSKGPLSEGATYYAQGGIAAVFDESDSIDSHVQDTLVAGAHLCDEAVVRFIAENAKNCVQWLIDGGVPFDQEEASDEQSPRYHLTREGGHSHRRILHAADATGMAMQKSLQENVIDHPNINLLERHNALDLITTHKLGQMDKPNRVLGAYVWNRNQEQVETIRARFVVLATGGASKVYQYTSNPDVSSGDGIAMAWRAGCRVANLEFNQFHPTCLYHPDARNFLLTEALRGEGAYLRRPDGSRFMLEFDERAELAPRDIVARAIDYEMKRLGADCMYLDISHKPADFIIKHFPTIYEKLLTFGIDITQQPIPIVPAAHYTCGGVVVDTEGHTDLAGLYAIGEVSYTGLHGANRMASNSLLECVVYAYAAAQSIGEQWSEIAMPDSLPTWDESQVSCSDEEVVIQHNWHELRLFMWDYVGIVRSTKRLERAMRRIQLLKQEIDEYYGNFRVSNNLLELRNLVLVAELIVRCAMERKESRGLHYTLDYPDLEPNSHPTILTPHQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW11</accession>
    <name>D0YW11_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Response regulator of the LytR/AlgR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001316</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297852.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001316"/>
    <dbReference type="EnsemblBacteria" id="EEZ40291">
        <property type="protein sequence ID" value="EEZ40291"/>
        <property type="gene ID" value="VDA_001316"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3279">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1958442at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007492">
        <property type="entry name" value="LytTR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04397">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00850">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50930">
        <property type="entry name" value="HTH_LYTTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="3"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="HTH LytTR-type" evidence="3">
        <location>
            <begin position="135"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="237" mass="27242" checksum="8499D001F4716634" modified="2010-01-19" version="1">MLKALVIDDELFAREELIDLLEESQQVQVLDSSHNAIDGLKKIHSLKPDVVFLDIEMPQISGIELLTMLDPETMPKIVFVTAYDEYALQAFEDNAFDYLLKPVEPQRLTKTLTRLTRELEPKDYSPLIQEQLELIPCCGHNRILLLNIKEIEIAFSDLSGVHIVTKETKASSQLSLKILEQKSLLMRCHRQYLINPTAIREIRLLENNLAEIITISGHSVPVSRRYLKTLKERLQIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW38</accession>
    <name>D0YW38_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Translational regulator CsrA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Carbon storage regulator</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">csrA</name>
        <name evidence="4" type="ORF">VDA_001301</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CsrA/RsmA family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297826.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001301"/>
    <dbReference type="EnsemblBacteria" id="EEZ40276">
        <property type="protein sequence ID" value="EEZ40276"/>
        <property type="gene ID" value="VDA_001301"/>
    </dbReference>
    <dbReference type="GeneID" id="57339825"/>
    <dbReference type="eggNOG" id="COG1551">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2032250at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048027">
        <property type="term" value="F:mRNA 5'-UTR binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006402">
        <property type="term" value="P:mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045947">
        <property type="term" value="P:negative regulation of translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045948">
        <property type="term" value="P:positive regulation of translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006109">
        <property type="term" value="P:regulation of carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.4380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00167">
        <property type="entry name" value="CsrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003751">
        <property type="entry name" value="CsrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036107">
        <property type="entry name" value="CsrA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34984">
        <property type="entry name" value="PTHR34984"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02599">
        <property type="entry name" value="CsrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117130">
        <property type="entry name" value="SSF117130"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00202">
        <property type="entry name" value="csrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0010">Activator</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0678">Repressor</keyword>
    <keyword evidence="1 3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0810">Translation regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="65" mass="7186" checksum="C729DE5198D25BCB" modified="2010-01-19" version="1">MLILTRRVGETLMIGDEVTVTVLGVKGNQVRIGVNAPKEVSVHREEIYMRIQAEKETGTPSTGNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWB3</accession>
    <name>D0YWB3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Acetyltransferase component of pyruvate dehydrogenase complex</fullName>
            <ecNumber evidence="7">2.3.1.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_001195</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>(R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + acetyl-CoA = (R)-N(6)-(S(8)-acetyldihydrolipoyl)-L-lysyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:17017"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:10478"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="ChEBI" id="CHEBI:83111"/>
            <dbReference type="EC" id="2.3.1.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
        <text evidence="7">Binds 3 lipoyl cofactors covalently.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 7">Forms a 24-polypeptide structural core with octahedral symmetry.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.12" evidence="7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297615.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001195"/>
    <dbReference type="EnsemblBacteria" id="EEZ40173">
        <property type="protein sequence ID" value="EEZ40173"/>
        <property type="gene ID" value="VDA_001195"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0508">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1626282at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045254">
        <property type="term" value="C:pyruvate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004742">
        <property type="term" value="F:dihydrolipoyllysine-residue acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006256">
        <property type="entry name" value="AcTrfase_Pyrv_DH_cplx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004167">
        <property type="entry name" value="PSBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43178:SF2">
        <property type="entry name" value="PTHR43178:SF2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02817">
        <property type="entry name" value="E3_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47005">
        <property type="entry name" value="SSF47005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01348">
        <property type="entry name" value="PDHac_trf_long"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51826">
        <property type="entry name" value="PSBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5 7" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="4 7" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="10" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="8">
        <location>
            <begin position="2"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="Lipoyl-binding" evidence="8">
        <location>
            <begin position="104"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="Lipoyl-binding" evidence="8">
        <location>
            <begin position="201"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="9">
        <location>
            <begin position="321"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ40173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="625" mass="65124" checksum="1DECE82FB09E4D26" modified="2010-01-19" version="1">MAIEINVPDIGADEVEVTEILVSVGDKVEEEQSLITVEGDKASMEVPASQAGIVKEIKIAEGDKVSTGSLIMIFEAEGAATAAPAPAAEAAPVAASAPAAAAELKEVHVPDIGGDEVEVTEIMVSIGDSIEEEQSLLTVEGDKASMEVPAPFAGTLKEIKVATGDKVSTGSLIMIFEVAGSAPAAAPVAQAATPVATASAAKEVNVPDIGGDEVEVTEIMVAVGDTVEEEQSLITVEGDKASMEVPAPFVGTVKEIKIATGDKVSTGSLIMIFEVAGSAPVAAPVAQAAVPAPAAAPAPAATKAEAPAASSEFVENNEYSHASPVVRRLAREFGVNLAKVKGTGRKNRILKEDVQNFVKDALKRLESGAASGKGDGSALGLLPWPKVDFSKFGETEVQPLSRIKKISGANLHRNWVMIPHVTQWDNADITALEAFRKEQNAIEAKKDTGMKITPLVFIMKAAAKALEAFPAFNSSLSEDGESLILKKYVNIGIAVDTPNGLVVPVFKDVNKKGIYELSAELAEVSKKARAGKLTAADMQGGCFTISSLGGIGGTAFTPIVNAPEVGILGVSKSEMKPVWNGKEFEARLQLPLSLSYDHRVIDGAEGARFITYLNGCLSDIRRLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWE0</accession>
    <name>D0YWE0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Arsenate reductase</fullName>
            <ecNumber evidence="3">1.20.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001411</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>[glutaredoxin]-dithiol + arsenate + glutathione + H(+) = arsenite + glutathionyl-S-S-[glutaredoxin] + H2O</text>
            <dbReference type="Rhea" id="RHEA:22016"/>
            <dbReference type="Rhea" id="RHEA-COMP:10729"/>
            <dbReference type="Rhea" id="RHEA-COMP:17668"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29242"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:48597"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:146199"/>
            <dbReference type="EC" id="1.20.4.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 2 3">Belongs to the ArsC family.</text>
    </comment>
    <dbReference type="EC" id="1.20.4.1" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001411"/>
    <dbReference type="EnsemblBacteria" id="EEZ40385">
        <property type="protein sequence ID" value="EEZ40385"/>
        <property type="gene ID" value="VDA_001411"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1393">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008794">
        <property type="term" value="F:arsenate reductase (glutaredoxin) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03034">
        <property type="entry name" value="ArsC_ArsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006659">
        <property type="entry name" value="Arsenate_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006660">
        <property type="entry name" value="Arsenate_reductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30041">
        <property type="entry name" value="PTHR30041"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03960">
        <property type="entry name" value="ArsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00014">
        <property type="entry name" value="arsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51353">
        <property type="entry name" value="ARSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="99" mass="11065" checksum="3EE323CD2CB0C054" modified="2010-01-19" version="1">MALLEEQGVTPDVVKYLDTPPSVDALKALFTQLGFAQVRDMMRTKEDIYKELNLGDASITDEQLFEAMHSHPKLIERPIVVNNNQAAMGRPPENVLSVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWH7</accession>
    <name>D0YWH7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Phosphate starvation-inducible protein PhoH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_001436</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PhoH family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298062.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001436"/>
    <dbReference type="EnsemblBacteria" id="EEZ40410">
        <property type="protein sequence ID" value="EEZ40410"/>
        <property type="gene ID" value="VDA_001436"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1702">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="445854at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003714">
        <property type="entry name" value="PhoH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02562">
        <property type="entry name" value="PhoH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PhoH" evidence="5">
        <location>
            <begin position="119"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="334"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="353"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="372" mass="41755" checksum="F7F6FA926DAF4B06" modified="2010-01-19" version="1">MSKIITEELTLEPANNQRLSSLCGPFDDNIKHLERRLGVEINHRSNLFTVVGQPHTVAATINIIKNLYVDTAPVHNNIPDIEPDAIHLAIKESGVLEQNVESSIPYGKEVHIKTKKGIIKPRTPNQAQYITNMVTHDITFGIGPAGTGKTYLAVAAAVDALERQEIRRILLTRPAVEAGEKLGFLPGDLSQKVDPYLRPLYDALFEMLGFERVEKLIERNVIEVAPLAYMRGRTLNDAFIILDESQNTTVEQMKMFLTRIGFNSRAVITGDVTQIDLPRGARSGLRHAIEVLSEVDDISFNFFQANDVVRHPVVARIVQAYEVWESEDQKQRKLAEQRRRQEQEAKQAEQLAVAMANIQNPATKPTEPQQSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWN0</accession>
    <name>D0YWN0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">dTDP-4-dehydrorhamnose reductase</fullName>
            <ecNumber evidence="5 7">1.1.1.133</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_001521</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>dTDP-beta-L-rhamnose + NADP(+) = dTDP-4-dehydro-beta-L-rhamnose + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:21796"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57510"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:62830"/>
            <dbReference type="EC" id="1.1.1.133"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="7">Binds 1 Mg(2+) ion per monomer.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Bacterial outer membrane biogenesis; LPS O-antigen biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Carbohydrate biosynthesis; dTDP-L-rhamnose biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 7">Belongs to the dTDP-4-dehydrorhamnose reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.133" evidence="5 7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298208.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001521"/>
    <dbReference type="EnsemblBacteria" id="EEZ40495">
        <property type="protein sequence ID" value="EEZ40495"/>
        <property type="gene ID" value="VDA_001521"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1091">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1076083at2"/>
    <dbReference type="UniPathway" id="UPA00124"/>
    <dbReference type="UniPathway" id="UPA00281"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008831">
        <property type="term" value="F:dTDP-4-dehydrorhamnose reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019305">
        <property type="term" value="P:dTDP-rhamnose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009243">
        <property type="term" value="P:O antigen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005913">
        <property type="entry name" value="dTDP_dehydrorham_reduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029903">
        <property type="entry name" value="RmlD-like-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10491">
        <property type="entry name" value="PTHR10491"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04321">
        <property type="entry name" value="RmlD_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01214">
        <property type="entry name" value="rmlD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0521">NADP</keyword>
    <keyword evidence="7 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RmlD_sub_bind" evidence="8">
        <location>
            <begin position="1"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ40495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="296" mass="32642" checksum="E5BD999F2B756515" modified="2010-01-19" version="1">MKVLITGCNGQVGSCLVEQLQTFPNTEILAVDRNELDITSQYDVIKSVNEFKPHIIINAAAHTAVDKAETEVDLSYAINRDGPLYLAQAAENVGATLLHISTDYVFSGDKDGMYIETDTVDPQGVYGKSKLAGENAVLDNCSRSIILRTAWVFGEEGNNFVKTMLRLAQQRDELGIVADQFGGPTYARDIATALISIARTIIAEGSNFELSKYGIYHYSGLPHTSWYGFAQTIFDKAVEQKVLNKAPIVNGIKTEDYLTPAKRPANSKLNIQKITETFDIQASDWQCALNQLSDYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWN3</accession>
    <name>D0YWN3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative ARAC-type regulatory protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001489</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298147.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001489"/>
    <dbReference type="EnsemblBacteria" id="EEZ40463">
        <property type="protein sequence ID" value="EEZ40463"/>
        <property type="gene ID" value="VDA_001489"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1268974at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020449">
        <property type="entry name" value="Tscrpt_reg_HTH_AraC-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00032">
        <property type="entry name" value="HTHARAC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="4">
        <location>
            <begin position="183"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="290" mass="33859" checksum="9BF803CC72F281A8" modified="2010-01-19" version="1">MNTTFHNVIDSILTERESFNRIWFASDLNTPPQFSYQVNFPRLELVLKGEYINELDDGEHGIHQVKLMAGDALYIPPNCWNKPNWDTECSVLSLLFGKRQLGFSLVSKLKDTPKFYDVQKHSIHAWTGHAIDPMLQALNMLAKEPVQAPMDEHLLLALLSYSQQMLKAPIHSDSKNRVEDLYQGICIYIQENFHRPITRETIANRFNVSPNHLSRIFRQQGHMRLADYISWVRIERAKFMLKKYPFRLTEVATRCGFQDVNYFCRVFKTKTGRTPSEYREKMGRAGREGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWV6</accession>
    <name>D0YWV6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 10">Trigger factor</fullName>
            <shortName evidence="8">TF</shortName>
            <ecNumber evidence="8">5.2.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">PPIase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">tig</name>
        <name evidence="12" type="ORF">VDA_001548</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8 9">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="8">About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.</text>
    </comment>
    <comment type="domain">
        <text evidence="8">Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8 10">Belongs to the FKBP-type PPIase family. Tig subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298254.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001548"/>
    <dbReference type="EnsemblBacteria" id="EEZ40522">
        <property type="protein sequence ID" value="EEZ40522"/>
        <property type="gene ID" value="VDA_001548"/>
    </dbReference>
    <dbReference type="GeneID" id="57342394"/>
    <dbReference type="eggNOG" id="COG0544">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="932993at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00303">
        <property type="entry name" value="Trigger_factor_Tig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005215">
        <property type="entry name" value="Trig_fac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008880">
        <property type="entry name" value="Trigger_fac_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037041">
        <property type="entry name" value="Trigger_fac_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008881">
        <property type="entry name" value="Trigger_fac_ribosome-bd_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036611">
        <property type="entry name" value="Trigger_fac_ribosome-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027304">
        <property type="entry name" value="Trigger_fact/SurA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30560">
        <property type="entry name" value="PTHR30560"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05698">
        <property type="entry name" value="Trigger_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05697">
        <property type="entry name" value="Trigger_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003095">
        <property type="entry name" value="Trigger_factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102735">
        <property type="entry name" value="SSF102735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109998">
        <property type="entry name" value="SSF109998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00115">
        <property type="entry name" value="tig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 8 10" id="KW-0132">Cell division</keyword>
    <keyword evidence="5 8 10" id="KW-0143">Chaperone</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8 9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8 9" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="11">
        <location>
            <begin position="161"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ40522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="432" mass="47518" checksum="EC9E7A24108D845C" modified="2010-01-19" version="1">MQVTVETTEGLERQLTITVPAANIEDAVTAELKKIAKNRRFDGFRPGKAPLKMVAKMFGASVRQDILGEVMQRHFIEAIVKEQINPAGAPTFTPVEMAEGQDLVFKATFEVFPEIALQGLDKVVVEKPVVEVTEADVDNMIETLRKQQATWTEVDAPAVADSRVTIDFEGTIDGEAFDGGKAEGFALAMGQGRMIPGFEDGIVGKKAGEEFNIEVTFPEEYHAENLKGKAAVFAIKLSKVEAQELPELTEEFVAKFGIENGSVDALKAEVRKNMERELKQAVKGRIKEQAINGLIEQNDIAVPAALIDQEINVLRQQAAQRFGGNAQNMPELPRELFEEQAKRRVVVGLLLGEVIKSEELKADEERVKAIIAEMASAYEDPTEVVAYYEGNEQLMNNMRNIALEEQAIDAIVAKAQVSDKEVGFNDLMNPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX00</accession>
    <name>D0YX00_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phage baseplate assembly protein V</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002053</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299290.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002053"/>
    <dbReference type="EnsemblBacteria" id="EEZ41021">
        <property type="protein sequence ID" value="EEZ41021"/>
        <property type="gene ID" value="VDA_002053"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4540">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1949949at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037026">
        <property type="entry name" value="Vgr_OB-fold_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="194" mass="21437" checksum="B009ADD61D168F3E" modified="2010-01-19" version="1">MLRQLVERIRSLEKEMVALREETEENRRSSCNIIRLGIVDSASEKTVDVVSGDNKATRIPFFVHCAGRVTHYRRPSAGEQCILINLGSGDNLNNSVALMGLPSTQYPCPTTEENQVMTDYGNGMTELYDLDKGSLKVAYPGGVLLKADIVQEGNLSVSGEVSDGVRSMRDDREIYNSHVHPHGEPNTGNTEQKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX45</accession>
    <name>D0YX45_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Fumarate hydratase class I</fullName>
            <ecNumber evidence="10">4.2.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">VDA_001839</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the reversible hydration of fumarate to (S)-malate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>(S)-malate = fumarate + H2O</text>
            <dbReference type="Rhea" id="RHEA:12460"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="EC" id="4.2.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 10">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4 10">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the class-I fumarase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.2" evidence="10"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001839"/>
    <dbReference type="EnsemblBacteria" id="EEZ40807">
        <property type="protein sequence ID" value="EEZ40807"/>
        <property type="gene ID" value="VDA_001839"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1838">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1951">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004333">
        <property type="term" value="F:fumarate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006091">
        <property type="term" value="P:generation of precursor metabolites and energy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004646">
        <property type="entry name" value="Fe-S_hydro-lyase_TtdA-typ_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004647">
        <property type="entry name" value="Fe-S_hydro-lyase_TtdB-typ_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036660">
        <property type="entry name" value="Fe-S_hydroAse_TtdB_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011167">
        <property type="entry name" value="Fe_dep_fumarate_hydratase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05681">
        <property type="entry name" value="Fumerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05683">
        <property type="entry name" value="Fumerase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001394">
        <property type="entry name" value="Fe_dep_fumar_hy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117457">
        <property type="entry name" value="SSF117457"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00722">
        <property type="entry name" value="ttdA_fumA_fumB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00723">
        <property type="entry name" value="ttdB_fumA_fumB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7 10" id="KW-0408">Iron</keyword>
    <keyword evidence="8 10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9 10 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fumerase" evidence="11">
        <location>
            <begin position="2"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="Fumerase_C" evidence="12">
        <location>
            <begin position="199"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR001394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF05681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF05683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ40807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="416" mass="44594" checksum="8F41D2CF1BE824E4" modified="2010-01-19" version="1">MQEMIDEGVRQAYTNPLNPLRASVVADPAGSRKNTRDNAPAVVHIDMVAGDKVDIQIAAKGGGSENKTKMVMLNPSDDIADWVEKTVPLMGAGWCPPGMIGIGVGGTAEKAAVLAKESLMEAIDIHELKERGAQNAEEELRLDIYERVNRLGIGAQGLGGLTTVLDVKIKSAPTHAASKPVCMIPNCAATRHVHFTLDGTGPAELTPPKLEDWPEVTWEVGDSVRRVNLDSVTKEDVLQWKSGETILLSGKILTGRDAAHKRIQDMLAKGEGLPDGVDFNGRFIYYVGPVDAVGDEVVGPAGPTTSTRMDKFTDMMLGETGLMGMIGKAERGPAAIESIKQHKAVYLMAVGGAAYLVAKAIKKARVVAFEELGMEAIYEFEVEDMPVTVAVDSEGVNAHQTGPDTWRIKIAEMQNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX62</accession>
    <name>D0YX62_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">P pilus assembly protein chaperone PapD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001851</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001851"/>
    <dbReference type="EnsemblBacteria" id="EEZ40819">
        <property type="protein sequence ID" value="EEZ40819"/>
        <property type="gene ID" value="VDA_001851"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3121">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008962">
        <property type="entry name" value="PapD-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49354">
        <property type="entry name" value="SSF49354"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="241" mass="26763" checksum="0F328F5344D80275" modified="2010-01-19" version="1">MDRISKIINIAFMILISMSQHAYAFKVQPMVSELAPIGSDSQLVMRVDNVDKKPLTIEVIPFELKIDSQGQETLVPADDEFLAVPVTAVIQPGRSQSVMVKYVGDPSIVQSKAYRISFRQVPIQLSEQEKGQLGLSVHINTLVNVAPKNSQSKLAVSDIQSQGQLWQMKLTNSGNKYARLSETTWKVIDSKGKQHNLNKQSVAKLSDSNIVLPKSNLIITIPKKNEFQNKPKAIEIKTVAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX69</accession>
    <name>D0YX69_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001854</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298821.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001854"/>
    <dbReference type="EnsemblBacteria" id="EEZ40822">
        <property type="protein sequence ID" value="EEZ40822"/>
        <property type="gene ID" value="VDA_001854"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5032WVZ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1425114at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018648" evidence="1">
        <location>
            <begin position="23"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="296" mass="33672" checksum="EC8773C2BA8E3C8E" modified="2010-01-19" version="1">MNLCLRNTLIIILCLFSSFTIADCNAQLRAITYSSGGDQYQVFGQHVNGLTQQYSLIIEGGDQRSCPLFLVIEPAVFPWALINHDNKRLEFDLEFKHNQVRQDSSKVIVDFSGENERISTQFSIRYPADQVVASGQYQGRLKFTLTANPHELNQYYDKEELTLQVAVVNTMKLSLYGIAGQYYRWDLGDLTQSGIRTNAPNLYIQSTEDFYVEVSSLNKGNLRHHSGQSKWDIPYQLLINSKVMNLHQVSSKQGYRLQPDGIKIPIEVEVPSVTQQRAGEYRDSVEIMITPTLGSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX97</accession>
    <name>D0YX97_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Multidrug resistance protein NorM</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Na(+)/drug antiporter</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001956</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299012.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001956"/>
    <dbReference type="EnsemblBacteria" id="EEZ40924">
        <property type="protein sequence ID" value="EEZ40924"/>
        <property type="gene ID" value="VDA_001956"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0534">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1415498at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006603">
        <property type="entry name" value="DinF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="59"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="95"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="135"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="164"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="196"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="224"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="289"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="321"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="365"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="400"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00030855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="455" mass="49579" checksum="462A876E333EE75C" modified="2010-01-19" version="1">MFTLVLQQFKGDFLRRLLLIALPISIQSMMFSSRSLVDILMLGQLGQTDVAAMGIAGRAIFVATIMLFGVTTGGALLTAQYWGAGNSEGVKRSTALTWLMSNITALIAAGVFFLSPESVISLATNNSEVVALGAQYLQITALSMFPMAFGISMAVGLRSMHQPGVSTFFSAIGISLNILLNWLLIFGKWGFPEMGIAGAAWATVISGVVEVSLLYAYLYHRKHLLSFGLSTIIAACEWIYVKRFLTLSLPTTFNHLAWSAGIFVYHAIIGQYGVEGLAALSVMTPIESLSLAFLIGSSNAAAVMIGNQLGANKMEEAYHQAWAVSCFNLLSSMVMAILMLLIKEPVLNLFTALTPETRALTEHFFVIYTGLLIIKSIPMTMIVGILRAGGDIRFCFYQDIIAQWVIGIPVVAICALVFKIPVEWIYALLGLEELVKWVGSTIRLRSKKWMNNLVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXA6</accession>
    <name>D0YXA6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Isocitrate dehydrogenase [NADP]</fullName>
            <ecNumber evidence="3">1.1.1.42</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001646</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>D-threo-isocitrate + NADP(+) = 2-oxoglutarate + CO2 + NADPH</text>
            <dbReference type="Rhea" id="RHEA:19629"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.42"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="1.1.1.42" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298435.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001646"/>
    <dbReference type="EnsemblBacteria" id="EEZ40619">
        <property type="protein sequence ID" value="EEZ40619"/>
        <property type="gene ID" value="VDA_001646"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0538">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1551125at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004450">
        <property type="term" value="F:isocitrate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006097">
        <property type="term" value="P:glyoxylate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019818">
        <property type="entry name" value="IsoCit/isopropylmalate_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004439">
        <property type="entry name" value="Isocitrate_DH_NADP_dimer_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43504">
        <property type="entry name" value="PTHR43504"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00183">
        <property type="entry name" value="prok_nadp_idh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00470">
        <property type="entry name" value="IDH_IMDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0329">Glyoxylate bypass</keyword>
    <keyword evidence="3" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Iso_dh" evidence="4">
        <location>
            <begin position="29"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="417" mass="45686" checksum="99F27CF3EFA2F11D" modified="2010-01-19" version="1">MDSKVVVPVDGQKITLDSDGKLVVPNTPIIPYIEGDGIGVDVSPAMIKVVDAAVQKAYGGDRKIAWMEIYTGEKSTHVYGEDAWLPQETLDFIREYKVAIKGPLTTPVGGGIRSLNVALRQELDLYICARPVRYFDGVPSPVKHPELTDMVIYRENSEDIYAGVEYQAGTVEAEQVINFLQKELGVTKIRFPQECGIGIKPISEEGTKRLVRAALQYTIDNDRDSLTIVHKGNIMKFTEGAFKDWSYEVAADEFGAQLLDGGPWMTLKNPNTGKEIVVKDCIADAFLQQILLRPAEYDVIATMNLNGDYISDALAAQVGGIGIAPGANIGDGVALFEATHGTAPKYAGQDKVNPGSLILSAEMMLRHLGWIEAADLIISSMEAAIRNKTVTYDFERLMEGATLRKCSEFADDMIEQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXF4</accession>
    <name>D0YXF4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Oligopeptide transport system permease protein OppB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_001633</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298411.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001633"/>
    <dbReference type="EnsemblBacteria" id="EEZ40606">
        <property type="protein sequence ID" value="EEZ40606"/>
        <property type="gene ID" value="VDA_001633"/>
    </dbReference>
    <dbReference type="GeneID" id="57342286"/>
    <dbReference type="eggNOG" id="COG0601">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1479518at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045621">
        <property type="entry name" value="BPD_transp_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19300">
        <property type="entry name" value="BPD_transp_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="100"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="133"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="174"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="228"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="274"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="94"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="306" mass="33586" checksum="A2C9B9F15E25EDD8" modified="2010-01-19" version="1">MIKFIAKRIFEAIPTLLVLITISFFLMRFAPGNPFSSDRPLPPEVMANIEAKYGLDKPVFEQYTTYLGNIVQGDFGPSFKYKDFTVNELVADAFPVSAKIGIAAFIFAVVMGVTVGTIAALKHNTWVDYLIMSTAMAGVVMPSFILAPVLIYIFSISMGWLPAGGWNDGSWQYMILPMFGMALLYVATFARITRGSMIETLNSNFIRTARAKGLSYPYIIIKHALKPALLPVVSYMGPAFVGIITGSVVIETIFGLPGIGKLFVNAAFNRDYSLVLGVTILIGTLTIVFNAIVDIVLAYIDPKIRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXJ1</accession>
    <name>D0YXJ1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_001705</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298546.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001705"/>
    <dbReference type="EnsemblBacteria" id="EEZ40676">
        <property type="protein sequence ID" value="EEZ40676"/>
        <property type="gene ID" value="VDA_001705"/>
    </dbReference>
    <dbReference type="GeneID" id="57342211"/>
    <dbReference type="eggNOG" id="COG0471">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="626718at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030676">
        <property type="entry name" value="CitT-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001898">
        <property type="entry name" value="SLC13A/DASS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00939">
        <property type="entry name" value="Na_sulph_symp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002457">
        <property type="entry name" value="DASS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00785">
        <property type="entry name" value="dass"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="34"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="55"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="96"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="139"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="163"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="186"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="227"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="271"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="293"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="324"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="356"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="406"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="446"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="471" mass="50906" checksum="9A1AE95BDC6A870A" modified="2010-01-19" version="1">MRQYIKYIVPILIPLLVVLLPAEAFPVEGLTVIQQRVIAIFLLAALCWVLEPIPIYATSVVIIVLELLLLSNKGFFLFQQGAGEPHFGELLNYSDIMATFASPIIMLFLGGFFLAMAATKYRLDVNLARVLLKPFGTQPKYVMLGLMLITAIFSMFMSNTATTAMMLSILAPVIALFGAKDPGKIAFALCIPVAANIGGIGTPIGTPPNAIALKYLSAENMITFGEWMFFGVPFVFILLMFAWVLLNALYPADQQKIELAIKGKFLKTPKAITVYITFGLTILLWLMGSTHGMNSYTVALIPVAIFSLTGIINKEDLKKISWDVLWLVSGGIALGLALDQTGLARLMVHSIPFDDYSPYVVLIGSAVLCLLMANFMSHTATANLLMPIMAALGTSMTSLVPLGGEITLILVVTFAASLGMSLPISTPPNALAHATGHVESNQMARVGVVIGVVGVILSFAMIWLLHLIDHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXM9</accession>
    <name>D0YXM9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative transcriptional regulator LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001770</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298667.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40738">
        <property type="protein sequence ID" value="EEZ40738"/>
        <property type="gene ID" value="VDA_001770"/>
    </dbReference>
    <dbReference type="GeneID" id="57342126"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="990666at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="291" mass="33196" checksum="946D5BF75F04D7BB" modified="2010-01-19" version="1">MDTRLLTYFHALAEAGNFTKAAEKLHIAQPALSVAIKKLEQQLELDLFHRNERKITLTHEGEVLLQHAKIILQQLKDANIAMAELRGLEKGEVRLGVPSMLGSYFFPQILMGFKSRYPNLKLTMVEAGTQSIRKMLVDGELDLGVIINENVPDSLNVEHLLTSQMVAVVSPEHPFAQQNQVNFDDFFQQEMVMFKTGYFHREFIDRVCSDYQLEPKISFETNLLPMILNIVRHDFAVSALLELVTEHESGVTAVPFATPVYLDIAMAWRKTGYLSLAERTFMDFVKQHCQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXR5</accession>
    <name>D0YXR5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNA chaperone ProQ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">proQ</name>
        <name evidence="6" type="ORF">VDA_002078</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ProQ family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299366.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002078"/>
    <dbReference type="EnsemblBacteria" id="EEZ41046">
        <property type="protein sequence ID" value="EEZ41046"/>
        <property type="gene ID" value="VDA_002078"/>
    </dbReference>
    <dbReference type="GeneID" id="57341810"/>
    <dbReference type="eggNOG" id="COG3109">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1659673at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033592">
        <property type="term" value="F:RNA strand annealing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034057">
        <property type="term" value="F:RNA strand-exchange activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010608">
        <property type="term" value="P:post-transcriptional regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00749">
        <property type="entry name" value="ProQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023529">
        <property type="entry name" value="ProQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016103">
        <property type="entry name" value="ProQ/FinO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036442">
        <property type="entry name" value="ProQ/FinO_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035236">
        <property type="entry name" value="ProQ_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38106">
        <property type="entry name" value="PTHR38106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04352">
        <property type="entry name" value="ProQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17516">
        <property type="entry name" value="ProQ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00945">
        <property type="entry name" value="ProQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48657">
        <property type="entry name" value="SSF48657"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1 3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="ProQ" evidence="5">
        <location>
            <begin position="5"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="103"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="120"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="210" mass="23560" checksum="E0D3E15DE5F7E56B" modified="2010-01-19" version="1">MENSEKLTNSKEVIAYIAERFPKCFTVEGEAKPLKIGIFQDLAERLEGDDKVSKTQLRTALRQYTSSWRYLHGVKAGAHRVDLDGNECEALEQEHVEHAQKALEESKAKVRARRKEQAAHKAAAKKDRDPKAKNSPKAKNVKPKSAKLNKKPVVETRKLTAEEIIEGKQVQVNMGSGNMPATIVEINKDDVRVRFNNGLVMAVKAEHLHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXU1</accession>
    <name>D0YXU1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">tRNA-cytidine(32) 2-sulfurtransferase</fullName>
            <ecNumber evidence="6">2.8.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Two-thiocytidine biosynthesis protein A</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">tRNA 2-thiocytidine biosynthesis protein TtcA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ttcA</name>
        <name evidence="8" type="ORF">VDA_002104</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>AH2 + ATP + cytidine(32) in tRNA + S-sulfanyl-L-cysteinyl-[cysteine desulfurase] = 2-thiocytidine(32) in tRNA + A + AMP + diphosphate + H(+) + L-cysteinyl-[cysteine desulfurase]</text>
            <dbReference type="Rhea" id="RHEA:57048"/>
            <dbReference type="Rhea" id="RHEA-COMP:10288"/>
            <dbReference type="Rhea" id="RHEA-COMP:12157"/>
            <dbReference type="Rhea" id="RHEA-COMP:12158"/>
            <dbReference type="Rhea" id="RHEA-COMP:14821"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61963"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="ChEBI" id="CHEBI:141453"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="6">Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">tRNA modification.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="6">The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the TtcA family.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.-" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299444.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002104"/>
    <dbReference type="EnsemblBacteria" id="EEZ41072">
        <property type="protein sequence ID" value="EEZ41072"/>
        <property type="gene ID" value="VDA_002104"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0037">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1051352at2"/>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00946"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016783">
        <property type="term" value="F:sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034227">
        <property type="term" value="P:tRNA thio-modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01850">
        <property type="entry name" value="TtcA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011063">
        <property type="entry name" value="TilS/TtcA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012089">
        <property type="entry name" value="tRNA_Cyd_32_2_STrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035107">
        <property type="entry name" value="tRNA_thiolation_TtcA_Ctu1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01171">
        <property type="entry name" value="ATP_bind_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004976">
        <property type="entry name" value="ATPase_YdaO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0408">Iron</keyword>
    <keyword evidence="5 6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 6" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="6" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="ATP_bind_3" evidence="7">
        <location>
            <begin position="42"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="PP-loop motif" evidence="6">
        <location>
            <begin position="47"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="213"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ41072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="309" mass="35108" checksum="2E1EDEDB9BED0347" modified="2010-01-19" version="1">MSDQNELTKAQQYNFNKLQKKLRRNVGNAIIDFNMIEDGDRIMVCLSGGKDSYAMLDILRSLQRSAPVKFELIAVNLDQKQPGFPDHILPEYLDTLGVEYKIVNEDTYSIVKEKIPEGKTTCSLCSRLRRGILYRTAKEIGATKIALGHHRDDMLETLFLNMFYGGKLKSMPPKLVSDNGEHVVIRPLAYCREKDIERFAELKEFPIIPCNLCGSQPNLQRQVIKDMLRDWDRRYPGRIETMFTALQNVVPSHLADFNLFDFKSVTKESGTIDGGDIAFDKQEIPAAPVSSDDVNEFDPGETLNVVQVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY09</accession>
    <name>D0YY09_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002172</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299585.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002172"/>
    <dbReference type="EnsemblBacteria" id="EEZ41140">
        <property type="protein sequence ID" value="EEZ41140"/>
        <property type="gene ID" value="VDA_002172"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0635">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1041554at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="327" mass="38089" checksum="CF81EB4783FFF064" modified="2010-01-19" version="1">MSDCTHYIEVPFECRHCCWFCGEPFYEHVSFMATPNYDGQKHPIMLPSCHECFGLAKDLKVSSLDLLRDKIKEKLHQKYQKHLQIGLNWTEDELRDCEFEGKALEGFRESAWMMYQIAKERVNYSGWDLVIDGIPLPKLTTVYQVEFDGVIYTSLHHAVTQLAQAYAIPETWLADVVELVGRDKLSYALRFCKTTYGYSAQERQASLDSLKMLLAEEAANQHSYNADEKNQVVHVIKLNVLKELMLYRTLIPTIPIKWALERGITTLSELASNEELFFSYFNQDSELTAFTYFNALQIYFEKREEDPLWAQQDDPNREVFLQIQGLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY48</accession>
    <name>D0YY48_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Quinone-reactive Ni/Fe hydrogenase large subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_002211</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">Heterodimer of a large and a small subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299657.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002211"/>
    <dbReference type="EnsemblBacteria" id="EEZ41179">
        <property type="protein sequence ID" value="EEZ41179"/>
        <property type="gene ID" value="VDA_002211"/>
    </dbReference>
    <dbReference type="GeneID" id="57341645"/>
    <dbReference type="eggNOG" id="COG0374">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1967820at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008901">
        <property type="term" value="F:ferredoxin hydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.645.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001501">
        <property type="entry name" value="Ni-dep_hyd_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018194">
        <property type="entry name" value="Ni-dep_hyd_lsu_Ni_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029014">
        <property type="entry name" value="NiFe-Hase_large"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00374">
        <property type="entry name" value="NiFeSe_Hases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56762">
        <property type="entry name" value="SSF56762"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00507">
        <property type="entry name" value="NI_HGENASE_L_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00508">
        <property type="entry name" value="NI_HGENASE_L_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0533">Nickel</keyword>
    <keyword evidence="5 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="567" mass="62490" checksum="234DE3FFC41A3EFB" modified="2010-01-19" version="1">MSKRVVIDPITRIEGHLRIEVELDENNVVEKAYASSTLFRGLEIIMKGRTPYDVGLLMQRICGVCTSSHYLCGTLAVEDAINAQVPLNAKYIRSLILSTLQLHDHIVHFYILHGMDWIDVVSALSADPAKAAQEAMKYSATPMAAGEGELRAVQEKVQGLVNTGNLGPFANAYWGNPTYKFTPEQNLIGLSHYLKALEIQRIAAECMALWGGKNPHPQSIVVGGVTCVRDMLDPARLQEFKQKFQHVAEFVERAYYADLVMAAKAYATSPDVLGGCNVHTFMAAESILLNPDDHLFTDGVIRNCDLSHAENVDPSLIEEDVTHAWYDAKQPQHPYDGTTIPEKTPFVQRETLMGNIPTINEAGKYSWVKSPRYNGEPVEVGPLATIAVNYARGNKPVVDVVDEFLTKTGLPAQALFTTLGRTAARMLHTTVIARHGLETFESMVANLNSDQTTYIKPTIDPDKEYKGVGILEAPRGLLSHWIRIKGGLVENYQAVVPTTWNAGPIDGNGRIGPYEASLVGLKLAEPTKPLEILRIIHSFDPCMACSVHVMDYKGQSLSEFRIAAQPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYB3</accession>
    <name>D0YYB3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_002276</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299773.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002276"/>
    <dbReference type="EnsemblBacteria" id="EEZ41244">
        <property type="protein sequence ID" value="EEZ41244"/>
        <property type="gene ID" value="VDA_002276"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1122">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="870493at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03225">
        <property type="entry name" value="ABC_cobalt_CbiO_domain1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022216">
        <property type="entry name" value="ABC_Co_transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015856">
        <property type="entry name" value="ABC_transpr_CbiO/EcfA_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12558">
        <property type="entry name" value="DUF3744"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="3"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="299"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="37"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="332"/>
            <end position="339"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="565" mass="63132" checksum="264720188D109C1B" modified="2010-01-19" version="1">MSIVFDNFTFKYWALEKPTLKNINLTINKGEKIVIVGPSGSGKSTLGQCLNGLIPHAIKGDCSGTLTINGQDTQKLKLDDCTSMVGTVLQDTDGQFVGLSVGEDIAFVLENQMIEQKEMHNIVQATADMMDLTSIIDLSPFDLSGGQKQRVSLAGVMVDDVEILLFDEPLASLDPKTGKAAIEIIDDLHQKTGKTVIIIEHRLEDVLHRPVDRIIMMERGEIVADLTPNQLLASSLLTEHGIREPLYLTALKEAGCDITEQDNPAYFNQMPLEKFKPHVEHWFTQAKLPEHQTSQEVLLSLNNLAYSYDGERQTLQNVSFDVHKGEFVAVLGKNGSGKSTLTRLIMGVLEPDQGTICLNGEDLTNSTIFERSQRIGVVMQNPNHMISHHMIFDEVASGLRNRGMAEEMVEEKVYAMLELCGLGRYRDWPIDALSYGQKKRVTIATILVLEPELLILDEPTAGQDYHHYTMMMEFVKELNQKLGITIMIVSHDMHLVLEYTDRAVVICDSELLADEAVNSVFSQPELLDKANLTVTSLYSLAQAMGIERIDNFIRCFIEHEARTKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYE1</accession>
    <name>D0YYE1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">LUD_dom domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002304</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299826.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002304"/>
    <dbReference type="EnsemblBacteria" id="EEZ41272">
        <property type="protein sequence ID" value="EEZ41272"/>
        <property type="gene ID" value="VDA_002304"/>
    </dbReference>
    <dbReference type="GeneID" id="57341512"/>
    <dbReference type="eggNOG" id="COG1556">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1580190at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024185">
        <property type="entry name" value="FTHF_cligase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003741">
        <property type="entry name" value="LUD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02589">
        <property type="entry name" value="LUD_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LUD_dom" evidence="1">
        <location>
            <begin position="69"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="249" mass="27368" checksum="2BE424B74F271D89" modified="2010-01-19" version="1">MTTQNEDRIYNRDSFLNNIAQKLGRERQTTPVERPAFRYNCHREVMADKSADELRDTLVQYTETALGSHAVVTTKAKLTEDLRNICVSYSTHQETGEVEGETIFSADPRLLALINPLDLISGKHSVHVWDAEAGFNANIEVAERAQAGVVFAEQVLAESGTMVLYSQASQGRTVSLLPEASVFVVPKSAIVARMTQATDKLHKMAQNGERIPSCVNFISGPSSTADIELIKVVGVHGPVYATYVIIDDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYG8</accession>
    <name>D0YYG8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Translation initiation factor IF-3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_002331</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the IF-3 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002331"/>
    <dbReference type="EnsemblBacteria" id="EEZ41299">
        <property type="protein sequence ID" value="EEZ41299"/>
        <property type="gene ID" value="VDA_002331"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0290">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036788">
        <property type="entry name" value="T_IF-3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036787">
        <property type="entry name" value="T_IF-3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019813">
        <property type="entry name" value="Translation_initiation_fac3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001288">
        <property type="entry name" value="Translation_initiation_fac_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019815">
        <property type="entry name" value="Translation_initiation_fac_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019814">
        <property type="entry name" value="Translation_initiation_fac_3_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10938">
        <property type="entry name" value="PTHR10938"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00707">
        <property type="entry name" value="IF3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05198">
        <property type="entry name" value="IF3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54364">
        <property type="entry name" value="SSF54364"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55200">
        <property type="entry name" value="SSF55200"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00168">
        <property type="entry name" value="infC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00938">
        <property type="entry name" value="IF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 7" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IF3_N" evidence="6">
        <location>
            <begin position="2"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="domain" description="IF3_C" evidence="5">
        <location>
            <begin position="49"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF05198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="137" mass="15690" checksum="D6E9FC5B4A9BC76C" modified="2010-01-19" version="1">MNAAHEAGVDLVEISPNAEPPVCRVMDYGKYLFEKSKAAKEQKKKQKQIQIKEVKFRPGTDEGDYQVKLRNLSRFLEEGNKGKVTLRFRGREMAHQSIGIELLNRIKDDLIDLAVVESFPSRVEGRQMTMMLAPKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYL9</accession>
    <name>D0YYL9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ATPase involved in DNA repair</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002382</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299994.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002382"/>
    <dbReference type="EnsemblBacteria" id="EEZ41350">
        <property type="protein sequence ID" value="EEZ41350"/>
        <property type="gene ID" value="VDA_002382"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502Z831">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1206096at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="253" mass="28978" checksum="207ED6779DF9A3FB" modified="2010-01-19" version="1">MSIPLIIGLVALLLALIIGYNVTVQYRLRIQSAKQQELGQYIAIIDATEELIGHAHHIPYSKELLLCLNKRILNALKSMADIDPNDKKLAQRIEDVGQQIESLQNHFSDTEITPFKVPTTDRQAIGMLQLVKRLKTIVKNEHSKGRIATQVFVTENARLEAMQLRINMENVIKRANEARLKQQFGTAQQLLKKAIDVLDARNDNYSNQTRERLQAMLSDISNSQSKNQADERQQMIAKEQDELDVLFQPKRKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYQ8</accession>
    <name>D0YYQ8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Potassium efflux system kefA/small-conductance mechanosensitive channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">VDA_002421</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MscS (TC 1.A.23) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002421"/>
    <dbReference type="EnsemblBacteria" id="EEZ41389">
        <property type="protein sequence ID" value="EEZ41389"/>
        <property type="gene ID" value="VDA_002421"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3264">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011066">
        <property type="entry name" value="MscS_channel_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011014">
        <property type="entry name" value="MscS_channel_TM-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025692">
        <property type="entry name" value="MscS_IM_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024393">
        <property type="entry name" value="MscS_porin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12795">
        <property type="entry name" value="MscS_porin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12794">
        <property type="entry name" value="MscS_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82689">
        <property type="entry name" value="SSF82689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82861">
        <property type="entry name" value="SSF82861"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018737" evidence="9">
        <location>
            <begin position="25"/>
            <end position="1102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="473"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="519"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="551"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="603"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="628"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="670"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="697"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="787"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="827"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="871"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="903"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="domain" description="MscS_porin" evidence="11">
        <location>
            <begin position="34"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="MscS_TM" evidence="10">
        <location>
            <begin position="478"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="108"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="261"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF12794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF12795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ41389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="1102" mass="126552" checksum="48D6D712990E04A3" modified="2010-01-19" version="1">MLGRRLFVLVCLMFTMLVTTPAHANENEQTLNDKIEYLNKQPQTPETIKELDIYLQAQNQVAKAKEFNRLTKQYDDLIDTFPKQVAALQNKIDAFSTSEFPEFNQWDKEQLTLEIAEQDNLLLQLESSRNAHKNILLEIERGIDNFTAQSDRLRRQLKSTELDLQQARRINDTNALLLLQINEQYLNSYLNMLEAEQLSSGNRRTLAKLQVQYDNQEIEARQAYRNNLQSTLNRVLRMASSDNQETGTELEESMSDQPLVIQQLLQANQRLSGELNNLNYQNEQTQQQAVTANKQISEVTKTADDLNAMTDLLKLSPAFSESMRNRIKGLPSNPPIEALDNSIGRNQLKKYEYQQQVDSLSQRQKHITSSGLTPEQQVMAKELSDANIGLYNDLIAASESLIYQQAVLKVAYDKLNTKLTDLKNLAAKRLFWAPDTNPLSINLLIDTWEKLKWFFSPSQWINLLKAPMVINHFILLTIIVVSGLLISGQIWARKRWKKYLEKTSAKIGRVTMDKFRYSYINVFVAFCFAWVIPLVITLFGYGLQEAWQYPFVHHLGQAIVYPMALVVFFFIRELVRKNGLFISHFGWDDFVVNPTFAHYRRLLWIYIPMMVIQNFALNYSDIEVNGTLGRLAFIISNCALSYFHYRMWQQKLPMTYGDVPEGKAHLGHHLFWWTLILVPQILNYSALNGYLGSSQAIMLRMEQSAVLGVVTMLIYYLCKRLMLIQKRRLAFERAKAKRQEIIAQRQAEVQGDKEENFSTSEINIEIEEPEIDLDKISAQSLRLLRSLLLLIYLAMMAWLLSDLYLATSSLQNVTLWDVTSKINGIDQLSAITLNSVLLAVLTFGLTTILARDLPAAMELLILQHLDLRPGTGYAITSLTRYFAIFIGIIVGSGLIGFDWSKMQWLVAALGVGIGFGMQEIFANFISGLIILFEKPIRIGDTVTIRDLTGMVTKIQTRATTIVDWDRKEVIMPNKAFVTEQFVNWSLSDSITRVKLFINVEYVADPELVTQLLFDAAHECRLVLDDPAPEVFFLGLDANCQRFEVRAYAAETGHRLSLTHDLHCRIKNKFMDHSIMIAHPQLEVTMKKQELHPMRKSFRSRKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYY0</accession>
    <name>D0YYY0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative ferrous iron transport protein A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_002493</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FeoA family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002493"/>
    <dbReference type="EnsemblBacteria" id="EEZ41461">
        <property type="protein sequence ID" value="EEZ41461"/>
        <property type="gene ID" value="VDA_002493"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1918">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046914">
        <property type="term" value="F:transition metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007167">
        <property type="entry name" value="Fe-transptr_FeoA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038157">
        <property type="entry name" value="FeoA_core_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008988">
        <property type="entry name" value="Transcriptional_repressor_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04023">
        <property type="entry name" value="FeoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50037">
        <property type="entry name" value="SSF50037"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FeoA" evidence="3">
        <location>
            <begin position="3"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="47" mass="5161" checksum="43C1EBB769179192" modified="2010-01-19" version="1">MVMGLLPHTEVAVVRLAPLGDPLQIRVRGVDIALRKQIAESIEVEVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYY1</accession>
    <name>D0YYY1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cell wall endopeptidase family M23/M37</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_002494</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300198.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002494"/>
    <dbReference type="MEROPS" id="M23.014"/>
    <dbReference type="EnsemblBacteria" id="EEZ41462">
        <property type="protein sequence ID" value="EEZ41462"/>
        <property type="gene ID" value="VDA_002494"/>
    </dbReference>
    <dbReference type="GeneID" id="57341282"/>
    <dbReference type="eggNOG" id="COG0739">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1891666at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042834">
        <property type="term" value="F:peptidoglycan binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045834">
        <property type="entry name" value="Csd3_N2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013731">
        <property type="entry name" value="OapA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007340">
        <property type="entry name" value="Opacity-associatedA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19425">
        <property type="entry name" value="Csd3_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04225">
        <property type="entry name" value="OapA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08525">
        <property type="entry name" value="OapA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LysM" evidence="5">
        <location>
            <begin position="102"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="449" mass="50136" checksum="FF7D84F7394711FD" modified="2010-01-19" version="1">MKLYQVAVSSIKGLPRQHKIALASTSLLVMAALMWQPSKSTYRAPIISGERVAIDLAHDNIEVLSEQNSEPLGVILDPQDPEFQAPKDDLDKELEAVKDEEHKHKVASGDTLGSIFSQYGLPVSDMYALIDANKSIQHLKVGQQMEWSLDSDGRVKDFSIVRDRKTTDTFTLTKKGYKYKAVEIAGVIKPVILHGKVTGSFYNSARNAGLSPTQIKTVVKALQWKFNLGSGASRGDRFAISLDREFIDGKPVNMGDVNAFFYKHGNQTYFIQRFDDDQFFDQSGRSLNRSFRRYPTAKRYRISSSFNPHRRHPITRRISPHNGTDFAVPVGTPVLASGDGVVVKSRYHPLAGNYIVIKHGREFTTRYLHLSKRLVKVGDRIKMGQRIALSGNTGRSTGPHLHYELIKNGHPVNAMKVPLPQSDPLYGSKASKFRKEAKVEYKKLAAAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYY6</accession>
    <name>D0YYY6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Succinate--CoA ligase [ADP-forming] subunit beta</fullName>
            <ecNumber evidence="6">6.2.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Succinyl-CoA synthetase subunit beta</fullName>
            <shortName evidence="6">SCS-beta</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">sucC</name>
        <name evidence="9" type="ORF">VDA_002499</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>ATP + CoA + succinate = ADP + phosphate + succinyl-CoA</text>
            <dbReference type="Rhea" id="RHEA:17661"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.2.1.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="6">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Carbohydrate metabolism; tricarboxylic acid cycle; succinate from succinyl-CoA (ligase route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Heterotetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the succinate/malate CoA ligase beta subunit family.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.5" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300204.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002499"/>
    <dbReference type="EnsemblBacteria" id="EEZ41467">
        <property type="protein sequence ID" value="EEZ41467"/>
        <property type="gene ID" value="VDA_002499"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0045">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="316012at2"/>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER00999"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004775">
        <property type="term" value="F:succinate-CoA ligase (ADP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.261">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00558">
        <property type="entry name" value="Succ_CoA_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013650">
        <property type="entry name" value="ATP-grasp_succ-CoA_synth-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005811">
        <property type="entry name" value="CoA_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017866">
        <property type="entry name" value="Succ-CoA_synthase_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005809">
        <property type="entry name" value="Succ_CoA_synthase_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11815">
        <property type="entry name" value="PTHR11815"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08442">
        <property type="entry name" value="ATP-grasp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00549">
        <property type="entry name" value="Ligase_CoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001554">
        <property type="entry name" value="SucCS_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52210">
        <property type="entry name" value="SSF52210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01016">
        <property type="entry name" value="sucCoAbeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01217">
        <property type="entry name" value="SUCCINYL_COA_LIG_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 6 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 6" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="ATP-grasp" evidence="8">
        <location>
            <begin position="9"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding; shared with subunit alpha" evidence="6">
        <location>
            <begin position="321"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="53"/>
            <end position="55"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="213"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="264"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared with subunit alpha</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="388" mass="41342" checksum="5886B5D1046CADD1" modified="2010-01-19" version="1">MNLHEYQAKQLFAEYGLPVPEGYACSTPQEAAEAAGKIGGEKWVVKCQVHAGGRGKAGGVELHETKEGIKTFSQQWLGKHLVTYQTDANGQPVSKILVEAASNIANELYLGAVVDRASQRIVFMASTEGGVEIEKVAEETPELIHKAAIDPLVGPQAYQGRELAFKLGLTGDQIKQFTQIFLGLGKMFTDYDLALLEINPLVITDDGNLLCLDGKINIDANALYRQPKLREMHDPSQEDEREAHAAQWELNYVALDGNIGCMVNGAGLAMGTMDIVNLHGGQPANFLDVGGGATKERVTEAFKIILSDSNVKAVLVNIFGGIVRCDLIAEGIIGAIAEVGVKVPVVVRLEGNNAELGAAKLAESGLNIIAATSLTEAAEKVVQAAEGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYZ9</accession>
    <name>D0YYZ9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glutamine--tRNA ligase</fullName>
            <ecNumber evidence="9">6.1.1.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Glutaminyl-tRNA synthetase</fullName>
            <shortName evidence="9">GlnRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">glnS</name>
        <name evidence="13" type="ORF">VDA_002512</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln)</text>
            <dbReference type="Rhea" id="RHEA:20121"/>
            <dbReference type="Rhea" id="RHEA-COMP:9662"/>
            <dbReference type="Rhea" id="RHEA-COMP:9681"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78521"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.18"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="9">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 10">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.18" evidence="9"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300227.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002512"/>
    <dbReference type="EnsemblBacteria" id="EEZ41480">
        <property type="protein sequence ID" value="EEZ41480"/>
        <property type="gene ID" value="VDA_002512"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0008">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="142899at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004819">
        <property type="term" value="F:glutamine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006425">
        <property type="term" value="P:glutaminyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006424">
        <property type="term" value="P:glutamyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.240.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00126">
        <property type="entry name" value="Gln_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004514">
        <property type="entry name" value="Gln-tRNA-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022861">
        <property type="entry name" value="Gln_tRNA_ligase_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000924">
        <property type="entry name" value="Glu/Gln-tRNA-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020058">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020059">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_codon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020061">
        <property type="entry name" value="Glu_tRNA_lig_a-bdl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020056">
        <property type="entry name" value="Rbsml_L25/Gln-tRNA_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011035">
        <property type="entry name" value="Ribosomal_L25/Gln-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00749">
        <property type="entry name" value="tRNA-synt_1c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03950">
        <property type="entry name" value="tRNA-synt_1c_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00987">
        <property type="entry name" value="TRNASYNTHGLU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50715">
        <property type="entry name" value="SSF50715"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00440">
        <property type="entry name" value="glnS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-synt_1c" evidence="11">
        <location>
            <begin position="28"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA-synt_1c_C" evidence="12">
        <location>
            <begin position="340"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with tRNA" evidence="9">
        <location>
            <begin position="317"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="9">
        <location>
            <begin position="34"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="9">
        <location>
            <begin position="268"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="35"/>
            <end position="37"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="41"/>
            <end position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="261"/>
            <end position="262"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="269"/>
            <end position="271"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF03950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ41480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="555" mass="63577" checksum="3E0CDC0FC9C444ED" modified="2010-01-19" version="1">MSGTEARPTNFIRQIIDADLASGKHTSVHTRFPPEPNGYLHIGHAKSICLNFGIAQDYQGQCNLRFDDTNPEKEDIEYVESIKNDVNWLGFQWSGEICYSSNYFDKLHGFAIELINKGLAYVDELSPEQMREYRGTLTEPGKHSPYRDRSVEENLELFAKMKNGEVEEGKMCLRAKIDMASPFMVMRDPVLYRVRFATHHQTGDKWCIYPMYDFTHCISDALEGITHSICTLEFMDNRRLYDWVLENITIDCTPHQYEFSRLNLEYTVMSKRKLNQLVTDKLVNGWDDPRMPTISGLRRRGYTAGSIREFCKRIGVTKQDNTIEMSSLEACIREDLNENAPRAMAVLDPVKIVIENFDGEAETLNIANHPNKPEMGSREVPFTREVYIEREDFREEANKKYKRLVLGKEVRLRGAYVIKAERVEKDEAGNITTIYCTYDNETLGKNPADGRKVKGVIHWVSADQSVPAEIRLYDRLFTVPNPGAAEDFVSVINSESLTVMNGFVEPALVNAQAEQAYQFERLGYFCADSKDSSADKLVFNRTVGLRDTWAKIADE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ18</accession>
    <name>D0YZ18_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002531</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0319 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002531"/>
    <dbReference type="EnsemblBacteria" id="EEZ41499">
        <property type="protein sequence ID" value="EEZ41499"/>
        <property type="gene ID" value="VDA_002531"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3110">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018635">
        <property type="entry name" value="UPF0319"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38108">
        <property type="entry name" value="PTHR38108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09829">
        <property type="entry name" value="DUF2057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="207" mass="22913" checksum="D2C258C729364551" modified="2010-01-19" version="1">MIGAALSFGVQAATLTAGDNIELLVIDGKKIEQKGWSKAESVELANGEHQIVARFDGEVKRGSQGTIYTTRPYLFNVDIKDQNAEIVLSDTLTTLSQAEAYFARGPEWQVKFANGSEQVLDATELKGSGFAAYADMEKLVAQYNSENGIIFEQGNPVDLEKVAVKVDEQGKVKITGDNLTQLKMWYSKATPEEKKAFKMWMTEQDYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ25</accession>
    <name>D0YZ25_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Probable Co/Zn/Cd efflux system membrane fusion protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_002538</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300282.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002538"/>
    <dbReference type="EnsemblBacteria" id="EEZ41506">
        <property type="protein sequence ID" value="EEZ41506"/>
        <property type="gene ID" value="VDA_002538"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0845">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5569">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="949250at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021647">
        <property type="entry name" value="CusF_Ec"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042230">
        <property type="entry name" value="CusF_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045800">
        <property type="entry name" value="HMBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11604">
        <property type="entry name" value="CusF_Ec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19335">
        <property type="entry name" value="HMBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018746" evidence="2">
        <location>
            <begin position="23"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="domain" description="HMBD" evidence="4">
        <location>
            <begin position="42"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="3">
        <location>
            <begin position="104"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF19335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="492" mass="53999" checksum="6E3882ABB1CDE93D" modified="2010-01-19" version="1">MKNVFSISLLALAIGTGGGYFAATQFSDSSTEPSAKNKEPLYWVAPMDPNYKRDKPGKSPMGMDLIPVYEEDNGGKELAGTVKISPVVENNLGVKTANVISAPLTPQIDTVGYVAFDESQLWQINSRVSGWIKKLNVNAIGEQVKQGQVLFTLYSPELVRAQEELLNARRLGKTVLINGAKERLKSLGVDNSQINQLLKRGTASQTIAIKAPANGVIATLNVRQGAYLSPAQTVISAGSLQDVWVDVEVFERQAHWITLRTTADMKIDSLPGTQWQGKVDYIYPILDPKTRTLRIRVVFPNKDGALKPNMFANVELIPQSKNKVLQIPNQAVIRSGNMDRVVLALGEGKYRSTRIETGREAGDMIEVISGLTANDKIVTSAQFMIDSESSQTADLSRISQADQQADTKADTVWVDGTITKVMANHRMLTVHHQPVKAWNWPTMTMNFTVAKSVDLSDLSAKQSIRFELKKTPQGQFEIIAIQVANPATKVGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ39</accession>
    <name>D0YZ39_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_002552</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300308.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41520">
        <property type="protein sequence ID" value="EEZ41520"/>
        <property type="gene ID" value="VDA_002552"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3710">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="449786at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="133"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="6"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="1">
        <location>
            <begin position="6"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="470" mass="53144" checksum="85AA7CC965F945FB" modified="2010-01-19" version="1">MTHSHCFVLQHDTPISFYPEKNQLMIDGEAIHLEPLQARLLSYFIENRGKVLSAQQIATNVWQRTQVSDNLVRQVISLLRSQLQDKSRPYRIIQTIPKQGYLFDIEVTKEHSSVIEEAVFPTTFAAKSKNKSLIVAMTAVLTVGLIGAWAIQNVDTSDDTTVIATHQSDMIPVYIHDITLDSTSDFEMAESVYNYLFYGLNSAKSLSGYHYSQLSNQSKQSIANHGIELKSWIKKTDGNYVLSVLVQNNHQPSQNQKIEQTFNQDTFFDAIGDVILEIKAIIAPMSSNYEVTSHRVTSISNYDDWKVISEGISLFYQGKGGPAFSDIAQQLNTIQQQGRDNYLVSALLSYSESLTYLHEHKQADRKQALHLAKQAFELNPRCDIANLTLGLALLINQHPNQAFPYLFYAAESTPSPISFYLLSVADKLADNPKGSQYNYQRYTEMKKESKGQLFDLIESSQKTNLFQTPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ82</accession>
    <name>D0YZ82_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Flagellar motor switch protein FliM</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">VDA_002595</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell inner membrane</location>
            <topology evidence="10">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Bacterial flagellum basal body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the FliM family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300426.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002595"/>
    <dbReference type="EnsemblBacteria" id="EEZ41563">
        <property type="protein sequence ID" value="EEZ41563"/>
        <property type="gene ID" value="VDA_002595"/>
    </dbReference>
    <dbReference type="GeneID" id="57341161"/>
    <dbReference type="eggNOG" id="COG1868">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1748746at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003774">
        <property type="term" value="F:cytoskeletal motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17908">
        <property type="entry name" value="FliM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028976">
        <property type="entry name" value="CheC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001689">
        <property type="entry name" value="Flag_FliM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001543">
        <property type="entry name" value="FliN-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036429">
        <property type="entry name" value="SpoA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02154">
        <property type="entry name" value="FliM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01052">
        <property type="entry name" value="FliMN_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002888">
        <property type="entry name" value="FliM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00955">
        <property type="entry name" value="FLGMOTORFLIM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101801">
        <property type="entry name" value="SSF101801"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103039">
        <property type="entry name" value="SSF103039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01397">
        <property type="entry name" value="fliM_switch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="10" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="12" id="KW-0966">Cell projection</keyword>
    <keyword evidence="5 10" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="12" id="KW-0969">Cilium</keyword>
    <keyword evidence="6 10" id="KW-0283">Flagellar rotation</keyword>
    <keyword evidence="12" id="KW-0282">Flagellum</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FliMN_C" evidence="11">
        <location>
            <begin position="249"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR002888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ41563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="347" mass="39275" checksum="C8197E0F7001E6C7" modified="2010-01-19" version="1">MSDLLTQDEIDALLHGVGDVDDGPESNSSETGVITFDFSSQDRIVRGRMPTLELINERFARHMRISLFNMLRKTAEVSINGVQMMKFGEYQNTLYVPTSLNMVRFRPLKGTALVTMEARLIFILVENFFGGDGRFHAKIEGREFTPTERRIIQMLLKLVFEDYREAWSPVMGVEFEYLDSEVNPTMANIVSPTEVIVVSSFHIELDGGGGDFHVVMPYSMVEPIRELLDAGVQSDKMDTDVRWSRALREEIMDIPVNIRAKLLDVDLTLRDLMELQVGDIIPVDMPDTATVFVEDLPTYRAKMGRSGDNVALKISEKLKRPDMVKTELAFLERDALTRTLAAVADND</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZD2</accession>
    <name>D0YZD2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 15">Succinyl-diaminopimelate desuccinylase</fullName>
            <shortName evidence="15">SDAP desuccinylase</shortName>
            <ecNumber evidence="5 15">3.5.1.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14 15">N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">dapE</name>
        <name evidence="17" type="ORF">VDA_002645</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 15">
            <text>H2O + N-succinyl-(2S,6S)-2,6-diaminoheptanedioate = (2S,6S)-2,6-diaminoheptanedioate + succinate</text>
            <dbReference type="Rhea" id="RHEA:22608"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:57609"/>
            <dbReference type="ChEBI" id="CHEBI:58087"/>
            <dbReference type="EC" id="3.5.1.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="15">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <text evidence="15">Binds 2 Zn(2+) or Co(2+) ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 15">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; LL-2,6-diaminopimelate from (S)-tetrahydrodipicolinate (succinylase route): step 3/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 15">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the peptidase M20A family. DapE subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.18" evidence="5 15"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300588.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002645"/>
    <dbReference type="EnsemblBacteria" id="EEZ41613">
        <property type="protein sequence ID" value="EEZ41613"/>
        <property type="gene ID" value="VDA_002645"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0624">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="275025at2"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00021"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050897">
        <property type="term" value="F:cobalt ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009014">
        <property type="term" value="F:succinyl-diaminopimelate desuccinylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019877">
        <property type="term" value="P:diaminopimelate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01690">
        <property type="entry name" value="DapE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001261">
        <property type="entry name" value="ArgE/DapE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005941">
        <property type="entry name" value="DapE_proteobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01246">
        <property type="entry name" value="dapE_proteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00759">
        <property type="entry name" value="ARGE_DAPE_CPG2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 15" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="13 15" id="KW-0170">Cobalt</keyword>
    <keyword evidence="11 15" id="KW-0220">Diaminopimelate biosynthesis</keyword>
    <keyword evidence="9 15 17" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12 15" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="8 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 15" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="M20_dimer" evidence="16">
        <location>
            <begin position="177"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="active site" evidence="15">
        <location>
            <position position="70"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="15">
        <location>
            <position position="135"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="101"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="350"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00031891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EEZ41613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="377" mass="40990" checksum="2B9C366E303E2593" modified="2010-01-19" version="1">MSDSPVISLAKDLLSRRSVTPEDAGCQDVMIERLRQLGFCIETMVFNDTTNLWARRGTQAPLFVFAGHTDVVPSGPIEQWHTPPFEPTIKDGMLYGRGAADMKGSLACMIVAIERFIAENPDHQGSIGLLITSDEEGPFINGTTRVVDTLEARNEKIDLCIVGEPSSTLVVGDVVKNGRRGSITGDLTVKGIQGHVAYPHLADNPVHRALPALAELAAKTWDNGNDYFPPTSFQIPNINAGTGASNVVPGECQVQFNFRFSTELTDEAIKAQVHEILDQHQLDYHLNWTLSGHPFLTEKGTLVDAVVAAIEEVAHITPELSTSGGTSDGRFIARTGAQVIELGPVNATIHKVNECVKIEDLELLTDMYQKVLEKTLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZE4</accession>
    <name>D0YZE4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Na(+)-translocating NADH-quinone reductase subunit E</fullName>
            <shortName evidence="11">Na(+)-NQR subunit E</shortName>
            <shortName evidence="11">Na(+)-translocating NQR subunit E</shortName>
            <ecNumber evidence="11">7.2.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">NQR complex subunit E</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">NQR-1 subunit E</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">nqrE</name>
        <name evidence="12" type="ORF">VDA_002657</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a ubiquinone + H(+) + n Na(+)(in) + NADH = a ubiquinol + n Na(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:47748"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="7.2.1.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="11">Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="11">Cell membrane</location>
            <topology evidence="11">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the NqrDE/RnfAE family.</text>
    </comment>
    <dbReference type="EC" id="7.2.1.1" evidence="11"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300623.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002657"/>
    <dbReference type="EnsemblBacteria" id="EEZ41625">
        <property type="protein sequence ID" value="EEZ41625"/>
        <property type="gene ID" value="VDA_002657"/>
    </dbReference>
    <dbReference type="GeneID" id="57341077"/>
    <dbReference type="eggNOG" id="COG2209">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1814639at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009276">
        <property type="term" value="C:Gram-negative-bacterium-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016655">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00429">
        <property type="entry name" value="NqrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003667">
        <property type="entry name" value="NqrDE/RnfAE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010967">
        <property type="entry name" value="NqrE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30335:SF1">
        <property type="entry name" value="PTHR30335:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02508">
        <property type="entry name" value="Rnf-Nqr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006102">
        <property type="entry name" value="NQR_DE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01940">
        <property type="entry name" value="nqrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0520">NAD</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0915">Sodium</keyword>
    <keyword evidence="11" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="6 11" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <keyword evidence="9 11" id="KW-0830">Ubiquinone</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="39"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="106"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="172"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ41625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="198" mass="21545" checksum="2C0CD294EBE458B1" modified="2010-01-19" version="1">MEHYISLLVRSIFIENMALSFFLGMCTFLAVSKKVKTSFGLGIAVTVVLTIAVPVNNLVYTYLLKDGALVQGVDLSFLNFITFIGVIAALVQILEMVLDRFFPPLYNALGIFLPLITVNCAIFGGVSFMVQRDYNFTESIVYGLGSGIGWMLAIVALAGIREKMKYSDVPPGLRGLGITFITVGLMALGFMSFSGVQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZG6</accession>
    <name>D0YZG6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 10">3,4-dihydroxy-2-butanone 4-phosphate synthase</fullName>
            <shortName evidence="10">DHBP synthase</shortName>
            <ecNumber evidence="6 10">4.1.99.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ribB</name>
        <name evidence="12" type="ORF">VDA_002679</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 10">Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>D-ribulose 5-phosphate = (2S)-2-hydroxy-3-oxobutyl phosphate + formate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18457"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="ChEBI" id="CHEBI:58830"/>
            <dbReference type="EC" id="4.1.99.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="10">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="10">Binds 2 divalent metal cations per subunit. Magnesium or manganese.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Cofactor biosynthesis; riboflavin biosynthesis; 2-hydroxy-3-oxobutyl phosphate from D-ribulose 5-phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the DHBP synthase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">In the C-terminal section; belongs to the GTP cyclohydrolase II family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the N-terminal section; belongs to the DHBP synthase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.99.12" evidence="6 10"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300684.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002679"/>
    <dbReference type="EnsemblBacteria" id="EEZ41647">
        <property type="protein sequence ID" value="EEZ41647"/>
        <property type="gene ID" value="VDA_002679"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0108">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0807">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="900513at2"/>
    <dbReference type="UniPathway" id="UPA00275">
        <property type="reaction ID" value="UER00399"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008686">
        <property type="term" value="F:3,4-dihydroxy-2-butanone-4-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00180">
        <property type="entry name" value="RibB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017945">
        <property type="entry name" value="DHBP_synth_RibB-like_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000422">
        <property type="entry name" value="DHBP_synthase_RibB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032677">
        <property type="entry name" value="GTP_cyclohydro_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036144">
        <property type="entry name" value="RibA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00926">
        <property type="entry name" value="DHBP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00925">
        <property type="entry name" value="GTP_cyclohydro2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142695">
        <property type="entry name" value="SSF142695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55821">
        <property type="entry name" value="SSF55821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00506">
        <property type="entry name" value="ribB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0464">Manganese</keyword>
    <keyword evidence="9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0686">Riboflavin biosynthesis</keyword>
    <feature type="domain" description="GTP_cyclohydro2" evidence="11">
        <location>
            <begin position="208"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="D-ribulose 5-phosphate binding" evidence="10">
        <location>
            <begin position="27"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="D-ribulose 5-phosphate binding" evidence="10">
        <location>
            <begin position="140"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="28"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>D-ribulose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="site" description="Essential for catalytic activity" evidence="10">
        <location>
            <position position="126"/>
        </location>
    </feature>
    <feature type="site" description="Essential for catalytic activity" evidence="10">
        <location>
            <position position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00008976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00018836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ41647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="367" mass="39675" checksum="174258FF045889DE" modified="2010-01-19" version="1">MALSSAQEIIEDIRQGKMVILMDDEDRENEGDLIIAAEKITPDAINFMATHGRGLICLTLSKARCQKLNLPLMVKDNTEQFGTPFTISIEAAEGVTTGISAADRATTVQAAVAADATSADIVMPGHIFPLMAQEGGVLTRAGHTEAGCDVARLAGLEPSSVIVEILNEDGTMARRPQLEVFAEKHGLKLGTIADLIEYRNNNETTIERIAECQLPTEFGEFNMVTYRDKIDNAIHYALSKGEIHQSEPTLVRVHAQDTFKDILHSGATQWTLPSAMARIAAENGVLVILSKQESQESIVAKVKSLAAEAAGQPMVKFNPKAQSRQVGVGSQILADLGVGKMRLLSSSNQRYHSLSGFGLEVSEYICE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZK2</accession>
    <name>D0YZK2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ</fullName>
            <ecNumber evidence="4">2.1.1.200</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">tRNA (cytidine(32)/uridine(32)-2'-O)-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA Cm32/Um32 methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">trmJ</name>
        <name evidence="6" type="ORF">VDA_002715</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>S-adenosyl-L-methionine + uridine(32) in tRNA = 2'-O-methyluridine(32) in tRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42936"/>
            <dbReference type="Rhea" id="RHEA-COMP:10107"/>
            <dbReference type="Rhea" id="RHEA-COMP:10290"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74478"/>
            <dbReference type="EC" id="2.1.1.200"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>cytidine(32) in tRNA + S-adenosyl-L-methionine = 2'-O-methylcytidine(32) in tRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42932"/>
            <dbReference type="Rhea" id="RHEA-COMP:10288"/>
            <dbReference type="Rhea" id="RHEA-COMP:10289"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74495"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.200"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.200" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300796.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002715"/>
    <dbReference type="EnsemblBacteria" id="EEZ41683">
        <property type="protein sequence ID" value="EEZ41683"/>
        <property type="gene ID" value="VDA_002715"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0565">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1637132at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004384">
        <property type="entry name" value="RNA_MeTrfase_TrmJ/LasT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42786">
        <property type="entry name" value="PTHR42786"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004808">
        <property type="entry name" value="LasT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00050">
        <property type="entry name" value="rRNA_methyl_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="SpoU_methylase" evidence="5">
        <location>
            <begin position="5"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="243" mass="26898" checksum="D97E2CB73F146EDD" modified="2010-01-19" version="1">MLENIRIVLIGTSHSGNIGSAARAMKVMGLTNLVLVDPACEIDEQAMALAAGASDIVENATIVKTLDETIGDCGLVIGSSARSRTLEWPQLDPRESGIKTVNESASHPVAILFGRERTGLTNDELQKCHCHVYIPANPEYSSLNLAMAVQTISYEIRMAHLDAIKYQGDAKVEEYPRAKELELFYQHLEKILVKTQFINVKQPAMVMAKLRRLFTRARPELQELNILRGVLSSVEKSLPKSEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZL4</accession>
    <name>D0YZL4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PF03932 family protein CutC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">cutC</name>
        <name evidence="3" type="ORF">VDA_002727</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the CutC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300834.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002727"/>
    <dbReference type="EnsemblBacteria" id="EEZ41695">
        <property type="protein sequence ID" value="EEZ41695"/>
        <property type="gene ID" value="VDA_002727"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3142">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1728422at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00795">
        <property type="entry name" value="CutC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005627">
        <property type="entry name" value="Cu_homeostasis_CutC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036822">
        <property type="entry name" value="CutC_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12598">
        <property type="entry name" value="PTHR12598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03932">
        <property type="entry name" value="CutC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110395">
        <property type="entry name" value="SSF110395"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="245" mass="26403" checksum="A9FFFA25B0CFEE03" modified="2010-01-19" version="1">MTFQLEVCIDNIESLHLAQQGGATRIELCSSLALGGLTPSFGFMQAAVKYAQVPVYAMIRPRQGDFLFTDQDMEIMLADVHAAKQANLSGVVLGVLTDQGQVDKDQLKALIHQAQGMGVTFHRAIDQCIDPMATLDILMSLGCERILTSGLKANAYDGRDTLKEMVTYCGERLAIMAGAGVTAENVGQIISATGVREIHLSGKTTRPSLMKKYSNQAYMGNADIDDFAIPVTDANKIAAVAKQLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZL7</accession>
    <name>D0YZL7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Phosphate transport ATP-binding protein PstB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_002730</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300843.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002730"/>
    <dbReference type="EnsemblBacteria" id="EEZ41698">
        <property type="protein sequence ID" value="EEZ41698"/>
        <property type="gene ID" value="VDA_002730"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1117">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1416748at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015415">
        <property type="term" value="F:ATPase-coupled phosphate ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:inorganic phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03260">
        <property type="entry name" value="ABC_PstB_phosphate_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005670">
        <property type="entry name" value="Phosp_transpt1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43423">
        <property type="entry name" value="PTHR43423"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00972">
        <property type="entry name" value="3a0107s01c2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="26"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="58"/>
            <end position="65"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="272" mass="30380" checksum="C02D86D4F39A0630" modified="2010-01-19" version="1">MLTIDPTLGLYQSLDLTSLPEEQTALSIEGLNLFYGKSQALFDINMRIAKGQVTAFIGPSGCGKSTLLSCINRMNDLVEECHIDGKIVLNGQNIYDKQVDVAALRRRVGMVFQRPNPFPKSIYENVVYGLRLQGVKDRRVLDDAVESSLRGAALWDEVKDRLHENAFGLSGGQQQRLVIARAIAIEPEVLLLDEPTSALDPISTLTIEELINELKTKYTVIIVTHNMQQAARVSDQTAFMHMGELVEYASTNDIFTTPREKRTEDYITGRYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZM9</accession>
    <name>D0YZM9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">7-alpha-hydroxysteroid dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002742</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300880.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002742"/>
    <dbReference type="EnsemblBacteria" id="EEZ41710">
        <property type="protein sequence ID" value="EEZ41710"/>
        <property type="gene ID" value="VDA_002742"/>
    </dbReference>
    <dbReference type="GeneID" id="57340984"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1356861at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="265" mass="28195" checksum="6200CFCE1FE0AC88" modified="2010-01-19" version="1">MSVFTNKVALVLAGAQGIGKACSLLLAEQGATVYVADWAVEEAQATADEIKAKGGNAEGRFFNAFDNDSYAPLIDSILEKEGKIDVLVNNFGGVDLRVDRDLAHTDVADWEKNILANINSVFIPSKAVIPAMVKNGGGSIVNISSLSSLSAEMSSISYGTAKNAINHMTRQIAIQYASYGIRCNAVLPGMIATDAVKKNLNQEFIDNFLSTQPIKRMGEPEDIANAVGFLASDLAGFITGVCLPVTGGMNIATARYFFDADKVQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZN2</accession>
    <name>D0YZN2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">2-dehydro-3-deoxy-phosphogluconate aldolase</fullName>
            <ecNumber evidence="3">4.1.2.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_002745</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2-dehydro-3-deoxy-6-phospho-D-gluconate = D-glyceraldehyde 3-phosphate + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:17089"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:57569"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.1.2.14"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the KHG/KDPG aldolase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.14" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300893.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002745"/>
    <dbReference type="EnsemblBacteria" id="EEZ41713">
        <property type="protein sequence ID" value="EEZ41713"/>
        <property type="gene ID" value="VDA_002745"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0800">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1497385at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008675">
        <property type="term" value="F:2-dehydro-3-deoxy-phosphogluconate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00452">
        <property type="entry name" value="KDPG_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000887">
        <property type="entry name" value="Aldlse_KDPG_KHG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031337">
        <property type="entry name" value="KDPG/KHG_AS_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031338">
        <property type="entry name" value="KDPG/KHG_AS_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30246">
        <property type="entry name" value="PTHR30246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01081">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01182">
        <property type="entry name" value="eda"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00159">
        <property type="entry name" value="ALDOLASE_KDPG_KHG_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00160">
        <property type="entry name" value="ALDOLASE_KDPG_KHG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="214" mass="22644" checksum="01C9A5F0689D37E1" modified="2010-01-19" version="1">MNNNWTIAPQDVFAISPIIPVMVIERIEDAIPMAKALMEGGISIFEITLRTPVALEAMTLIANELPQALVGAGTVLTCAQYDAAVQAGAKFAISPGMSPSLLLHAQQGTVPLIPGVATPSEIMQALELGYDHLKFFPAEAYGGAQTLKAISAPLPQVTFCPTGGINTANVIEYKTVKSVATIGGSWMLPKDLIAQGQWEEITKLTKEAVTLLSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZQ2</accession>
    <name>D0YZQ2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002765</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002765"/>
    <dbReference type="EnsemblBacteria" id="EEZ41733">
        <property type="protein sequence ID" value="EEZ41733"/>
        <property type="gene ID" value="VDA_002765"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502Z8SK">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="713458at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="5"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="160"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="193"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="246"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="360"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="404"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="428"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="466" mass="51577" checksum="9321E01B84BB9DC1" modified="2010-01-19" version="1">MNTGLFFQIYVFITLIFSGTAQYFTGVSAFLWLPFIMTILMFCLLPLQTRYNFEPLDQIEITILILFLGLFVLALTSSLLQEGIKTTIAGVKNGLGMALLLPCLLLGFCRESQIYKVCQKLYWVFYAQIPFVIYEVLVIVPARVAAQGEMDSWDSVVGTFGGSMVAGGNGASMGLFTLLIMMMKLSEYKHGVTTLKSVLLHFAIGFSICIVAEVKFVTLLAPIFLLLVYIKPSYVKEVRVIDVKTILLAITGIVAILTIVITILSLGYASKYQSHSMSIFDIFIENIGYIFDPNTIVDGLDGNLDELGRLTALVFWSHNSDIYGFVNQLFGYGLNSSNAGGAEPGYIAMLFDLGLGSTALAIYLWEIGVVGVGLLLTIVYLILKNSNPRPMFSKTQLSEADIKLLSYQPAFIGFIIAGLITLPYAPLLALILVFQFQFYFSLGVIMIIRKVTLAKCEAHYDRINQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZQ3</accession>
    <name>D0YZQ3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sensor protein UhpB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002766</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002766"/>
    <dbReference type="EnsemblBacteria" id="EEZ41734">
        <property type="protein sequence ID" value="EEZ41734"/>
        <property type="gene ID" value="VDA_002766"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2244">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="595428at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="277"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="317"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="348"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="402" mass="45872" checksum="525DE47F39CF4293" modified="2010-01-19" version="1">MSLIKGASTIGGASVISQVIGAFTILFMSYRFGMSDVGNYSLIYGIILIGAQVALYGSHFLLPKVDQQDLGKAVVFGLLQSWIVSAAYIFVVSYFFSLPLMAIYVLTASYAMMIVSENILLRSKKFQRLAVQRISVTSIVSLSLLISWKVEYFYYIWAFAHLILICYWLYSSLDKNDFTLSDFSPTTQVKFLFKHWNHLSRVGTAEVVANASLQLPTVLINYWFSPLVAGYFAVVNRFCLSPVLILGQSVRNYTFSKWSEDFRNKTFNYVEFKQVRLFLISIALITVAGIYFVYPWLTEHVLGEQWVQSVETSRLMLPYVFAMLAFVPMTVIELIFGTPNYFLRIQCEQLAIVIIAFILIPFVYKSYVVSLLMFTVLTAARYLMIYIKINKDAVKLHEEGIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZU1</accession>
    <name>D0YZU1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">DNA repair protein RadA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">radA</name>
        <name evidence="8" type="ORF">VDA_002804</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.</text>
    </comment>
    <comment type="function">
        <text evidence="5">Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.</text>
    </comment>
    <comment type="domain">
        <text evidence="5">The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the RecA family. RadA subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301055.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002804"/>
    <dbReference type="MEROPS" id="S16.A04"/>
    <dbReference type="EnsemblBacteria" id="EEZ41772">
        <property type="protein sequence ID" value="EEZ41772"/>
        <property type="gene ID" value="VDA_002804"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1066">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="505485at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000725">
        <property type="term" value="P:recombinational repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01498">
        <property type="entry name" value="RadA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004504">
        <property type="entry name" value="DNA_repair_RadA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041166">
        <property type="entry name" value="Rubredoxin_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18073">
        <property type="entry name" value="Rubredoxin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00416">
        <property type="entry name" value="sms"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50162">
        <property type="entry name" value="RECA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5 6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0346">Stress response</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RECA_2" evidence="7">
        <location>
            <begin position="73"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Lon-protease-like" evidence="5">
        <location>
            <begin position="358"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="RadA KNRFG motif" evidence="5">
        <location>
            <begin position="259"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="102"/>
            <end position="109"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ41772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="462" mass="49298" checksum="8C065148B8D9F1D1" modified="2010-01-19" version="1">MAKAAKRAYVCSDCGADFPRWQGQCSACAAWNTITEFTIPKTKSAIGAAGSASGGYAGAPSKVQKLSDVESKDVPRFSSGISELDRVLGGGVVPGSVLLLCGDPGAGKSTLLLQSIGAVAAHKSALYVSGEESIHQISQRAKRLGTPNLDRINVVAETSVEQVINLIEQQKADFVIIDSIQTMTVAHNDSAAGSPSQVKESAAALTRYAKTHEVTFLIIGHINKDSNVAGPMQLIHIVDGLFALSSTADEKFRVLRTSKNRFGSDSESCFFAMTEQGMKQVKNPSAIFLSRSNKNHPGSTCTTLWEGTRPLLVEIQALCNQSVTENPRRLTVGYDSNRLAMSTAVLARHGGVRLSDMDIFVNCVGGIRIEETSADLAVLLSIFSSFKNAPIPQDVIVFGEIGLNGDIRPAANGLERIREAAKQGFTRAVVPKANASRQIPGIEIIPVEDLQEALEAFERVAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZV7</accession>
    <name>D0YZV7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative RTX toxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002820</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301102.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002820"/>
    <dbReference type="EnsemblBacteria" id="EEZ41788">
        <property type="protein sequence ID" value="EEZ41788"/>
        <property type="gene ID" value="VDA_002820"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2931">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4932">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002126">
        <property type="entry name" value="Cadherin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015919">
        <property type="entry name" value="Cadherin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001343">
        <property type="entry name" value="Hemolysn_Ca-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010221">
        <property type="entry name" value="VCBS_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00028">
        <property type="entry name" value="Cadherin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00353">
        <property type="entry name" value="HemolysinCabind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00112">
        <property type="entry name" value="CA"/>
        <property type="match status" value="16"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49313">
        <property type="entry name" value="SSF49313"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51120">
        <property type="entry name" value="SSF51120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01965">
        <property type="entry name" value="VCBS_repeat"/>
        <property type="match status" value="23"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50268">
        <property type="entry name" value="CADHERIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cadherin" evidence="2">
        <location>
            <begin position="172"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="2">
        <location>
            <begin position="2381"/>
            <end position="2484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="3098" mass="325054" checksum="9EDFBE99FA950BA8" modified="2010-01-19" version="1">MKSFVVTTTGKVQNVKGHVEATVGDQRVVLVTGQELPAGSQVFVSAPNSITLVSPDGEYWNSSESLEQQTTDVHSEIASIHQAILSGEDPSTVTEAPAAGNIVNGGGFGFVEVVRQGRESLAQTHYDTELSQSNTFDVFPSFESTPIATEPSAPTPPDNKPPVIVDINGQPIGDDLNVEVAEDSSINGQLTATDADGDDLTFELVDGSEPTNGQVTVNPDGSWEYVPNPDFNGEDSFTVVVDDGNGGTDTITVTVNVTPVNDAPIGEDVSVETQEETAVTGQLTATDADGDNLTFKPGTNPENGSVTINADGSWEYVPNTDFYGEDSFTVVVDDGNGGTDTITVTVNVTPVNDAPEGDDVSAETQEETAVTGQLTATDVDGDNLTFKSGTNPENGSVTVNPDGSWEYVPNTDFHGEDSFTVVVDDGNGGTDTITVTVNVTPVNDVPVGENVSAETQEDTAVTGQLTATDVDGDNLTFKPGTNPENGSVTINADGSWEYVPNPDFNGEDSFTVMVDDGNGGTDTITVTVNVTPVNDAPIGDDVSAETQEDTAVTGQLTATDVDGDNLTFKPGSDPTNGSVTVNPDGSWEYVPNPDFNGEDSFTVVVDDGNGGTDTITVTVNVTPANDAPVGEDVTAETQEETAVTGQLTATDADGDNLTFKPGSNPENGSVTINADGSWEYVPNPDFNGEDSFTVVVDDGNGGTDTITVTVNVTPINDAPVGEDVTAETQEETAVTGQLTATDVDSDNLTFKQGSDPTNGQVTVNPDGSWEYVPNPDFNGEDSFTVVVDDGNGGTDTITVTVNVTPANDAPVGENVTAETQEDTAVTGQLTATDADGDNLTFKPGSGPTNGSVTVNPDGSWEYVPNPDFNGEDSFTVVVDDGNGGSDTITVTVNVTPTNDAPIGDDVSTETQEETAVTGQLTATDADGDNLTFKPGTNPENGSVTINVDGSWEYVPNPDFNGEDSFTVVVDDGNGGTDTITVTVNVTPVNDAPVGENVTTETQEETAVTGQLTATDVDGDNLTFKPGSDPTNGSVTVNSDGSWEYVPNPDFNGEDSFTVVVDDGNGGSDTITVTVNVTPVNDAPVGEDVSAETQEETAVTGQLTATDVDGDNLTFKPGTNPENGSVTINADGSWEYVPNPDFNGEDSFTVVVDDGNGGTDTITVTVNVTPVNDAPVGENVSAETQEETAVTGQLTATDVDGDNLIFKPGTNPENGSVTVNPDGSWEYVPNTDFNGEDSFTVVVDDGNGGTDTITVTVNVTPINDAPVGEDVSAETQEETAVTGQLTATDVDGDNLTFKQGSDPTNGSVTVNPDGSWEYVPNPDFNGEDSFTVVVDDGNGGTDTITVTVNVTPANDAPVGEDVTAETQEETAVTGQLTATDVDGDNLTFKPGSDPTNGSVTVNPDGSWEYVPNPDFNGEDSFTVVVDDGNGGTDTITVTVNVTPVNDAPVGEDVSAETQEETAVTGQLTATDVDGDNLTFKPGSDPTNGSVTVNPDGSWEYVPNPNFNGEDSFTVVVDDGNGGTDTITVTVNVIPVNDAPVGENVTTETQEETAVTGQLTATDVDGDNLTFKPGTNPENGQVTVNADGSWEYVPNTDFNGEDSFTVVVDDGNGGTDTITVTVNVTPVNDAPVGEDVSAETQEETAVTGQLTATDIDGDNLTFKPGSDPTNGSVTVNPDGSWEYVPNPDFNGEDSFTVVVDDGNGGTDTITVTVNVTPVNDAPVGENVTTETQEDTAVTGQLTATDVDGDNLTFKPGSDPTNGQVTVNPDGSWEYVPNPDFNGEDSFTVVVDDGNGGTDTITVTVNVTPVNDAPEGEDISVETQEETAVTGQLTATDVDGDNLTFKQGSDPTNGQVTVNPDGSWEYVPNPDFNGEDSFTVVVDDGNGGTDTITVTVNVTPANDAPVGENVTAETQEDTAVTGQLTATDADGDNLTFKPGTNPENGSVTINADGSWEYVPNPDFNGEDSFTVVVDDGNGGTDTITVTVNVAPVNDAPVGEDVSAETQEETAVTGQLTATDVDGDNLTFKPGSDPTNGQVTVNPDGSWEYVPNPDFNGEDSFTVVVDDGNGGTDTITVTVNVTPVNDAPVGEDVSAETQEETAVTGQLTATDVDGDNLTFKPGANPENGSVTVNPDGSWEYVPNTDFNGEDSFTVVVDDGNGGTDTITVTVNVTPVNDEAVIGGDDHQSLIETNEVLTTGGTLTATDVDNPDNSFKPQEGVSGQYGQFTINSQGEWTFVSNGALDELAEGEVVTDHFVVESIDGTEHTITVEIVGTNEEPQAHDDRVTTKEDNAIALDLLSNDSDVDGTIQITQIAGVELTGGEQEITVENGQIRVAADGTLTFVPNANYSGDVSFDYQITDNHGATSEATVTIKVMPDNDAPEFDQDSYQFNYDENSTEGTVIGKVTATDIDSSALNYEISQGNDNGWFQINDKGEITLTEKGLLAAANDYELGDNEHQLQIIVSDGGKQTTVDVVLNEQNVNEAPTGQNIEITTNEDTAAILSWELFNAQDIDTPDSELSINITKLPANGVVQIQVDGQWQNITTSTLLTKAMFDNGDVRFVPELNHSSGMEGSEDTGNNGSIYAEFDFVISDGELQSPEYSTVIHVNAVADKVDIEFIIGQGVYHNGSIYQDGKDFISWEDTLINVGDKAHSLTEDTDSYQIKDKTAIKGNGGNDVISGHFSTEDLILIGDDGILGNNDVDVNLDGSPVNPANTVNDTLYGGSGNDILIGEQGNDSLYGNEGIDTAVFAGNFNDYHISNPTVSPGGSIFIQVTDKDYSLKSPFAGEGQDALYDIERLQFADGTYYWDQEDGQWVKEQPIMTYPLDINVTLTDLDGSESITEIRLAGLVEGAVLYASDGKTVLGIADAEGSITLTGLWNSSDSSVSLSDLKLVVDAELADQIKPTITVVNQENSNLDQNITHADGISMNGRSRSLFSVEQQDDESSMERAERLLSESEDEHPLLGLMQNQDDYQSSLLQEDILLDSVGVLTEQPEILSDFDIVNDKLDLSLLLTHATTETIDEYISFSQRDDNSVITINDQAEETEIILENITLDELSDNLGIITNGLLTYQEDELIFNDLASNSSQELTVIPNPVIDDNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZW2</accession>
    <name>D0YZW2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative c-di-GMP phosphodiesterase A-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_002825</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301118.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002825"/>
    <dbReference type="EnsemblBacteria" id="EEZ41793">
        <property type="protein sequence ID" value="EEZ41793"/>
        <property type="gene ID" value="VDA_002825"/>
    </dbReference>
    <dbReference type="GeneID" id="57340893"/>
    <dbReference type="eggNOG" id="COG5001">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAS" evidence="1">
        <location>
            <begin position="23"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="3">
        <location>
            <begin position="274"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="2">
        <location>
            <begin position="416"/>
            <end position="670"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="674" mass="76660" checksum="5AEEBFD7E4F0055E" modified="2010-01-19" version="1">MPTEQLQYWVPLLTDHSPYLFAIIDSQHRYVIVNQGYCNLSGLERNDLVGRNDSEVLGASYYRSLEPYYQRAFQGELIETEVLLEDSHHETSVQFTLCPLKNNNDAISYVAVYSHDTSERQLLVNSLDEQESLFNKINELVDDGLCIISDMMITKANTACAQLLGFSKPHEIVGKPLDQLLCDDTNTPYHLQQIIWKKTLYPSKNSAIEQPVLASSTPITLVGSPAYLLKLEKPNTQPEQQEHIEQLIHTDPLTGLYNRHGFTRQLEQHIQQQIPLLMLYLDIDNFKNINDSLGHNIGDRVLQEIGNRLSHLLPKHAIIGHLGGDEFCVLLPQADSEFSGEQLCQNVINQINQPFDLHHFRKHLACSIGLVQYPGDGNDARILLQNADTAMYEAKHRGRNRFIKFDDAMNKEARMRLWLEIELQKALQNQGLEVWYQPKVNARDFAINGAEALVRWKHPVEGYISPAQFIPVAEESGLIEQLGRVVMREVFSTVKKWKDRGLMPGRVAINLSPQQFGNPSLIAFMKQLKFQTGINPDDITFELTESAVMSDSEHTISMLKAIKQLGFALSIDDFGTGYSSLSYLARFPLDELKIDRAFIKDIDEVPKQVTLIENIINLGKALNMSLVAEGVETREQAILLSNLNCDYIQGFHFYRPQPKQELEGVLLQNKHRSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z016</accession>
    <name>D0Z016_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Autonomous glycyl radical cofactor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">grcA</name>
        <name evidence="5" type="ORF">VDA_002879</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Acts as a radical domain for damaged PFL and possibly other radical proteins.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301264.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002879"/>
    <dbReference type="EnsemblBacteria" id="EEZ41847">
        <property type="protein sequence ID" value="EEZ41847"/>
        <property type="gene ID" value="VDA_002879"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3445">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="116406at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00806">
        <property type="entry name" value="GrcA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019777">
        <property type="entry name" value="Form_AcTrfase_GR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001150">
        <property type="entry name" value="Gly_radical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011140">
        <property type="entry name" value="Glycyl_radical_cofactor_GrcA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01228">
        <property type="entry name" value="Gly_radical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000378">
        <property type="entry name" value="Gly_radicl_yfiD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04365">
        <property type="entry name" value="spare_glycyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00850">
        <property type="entry name" value="GLY_RADICAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51149">
        <property type="entry name" value="GLY_RADICAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 3" id="KW-0556">Organic radical</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycine radical" evidence="4">
        <location>
            <begin position="5"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="modified residue" description="Glycine radical" evidence="2 3">
        <location>
            <position position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="125" mass="13792" checksum="4CFBA9E2EE474B27" modified="2010-01-19" version="1">MITGIQITKAANEALLNTIWILDSETNEARCVVAAAGFEADQVVPAADLGDIEYRELAIEAPAKIEGGQHLNVNVLKRETLEEAVKHPELYPQLTIRVSGYAVRFNSLTPEQQRDVISRTFTNSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z070</accession>
    <name>D0Z070_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA topoisomerase 4 subunit A</fullName>
            <ecNumber evidence="5">5.6.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Topoisomerase IV subunit A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">parC</name>
        <name evidence="7" type="ORF">VDA_002933</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">Heterotetramer composed of ParC and ParE.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301383.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002933"/>
    <dbReference type="EnsemblBacteria" id="EEZ41901">
        <property type="protein sequence ID" value="EEZ41901"/>
        <property type="gene ID" value="VDA_002933"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0188">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="217468at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019897">
        <property type="term" value="C:extrinsic component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003918">
        <property type="term" value="F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00187">
        <property type="entry name" value="TOP4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.268.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.199.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00936">
        <property type="entry name" value="ParC_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006691">
        <property type="entry name" value="GyrA/parC_rep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035516">
        <property type="entry name" value="Gyrase/topoIV_suA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013760">
        <property type="entry name" value="Topo_IIA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013758">
        <property type="entry name" value="Topo_IIA_A/C_ab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013757">
        <property type="entry name" value="Topo_IIA_A_a_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002205">
        <property type="entry name" value="Topo_IIA_dom_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005742">
        <property type="entry name" value="TopoIV_A_Gneg"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03989">
        <property type="entry name" value="DNA_gyraseA_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00521">
        <property type="entry name" value="DNA_topoisoIV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00434">
        <property type="entry name" value="TOP4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101904">
        <property type="entry name" value="SSF101904"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56719">
        <property type="entry name" value="SSF56719"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 5 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="TOP4c" evidence="6">
        <location>
            <begin position="12"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-tyrosine intermediate" evidence="5">
        <location>
            <position position="124"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="5">
        <location>
            <position position="43"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="5">
        <location>
            <position position="79"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="5">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="5">
        <location>
            <position position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="754" mass="84531" checksum="3587C43B108EC9D7" modified="2010-01-19" version="1">MTDMTMDGVEQLPLRKFTEDAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLSATAKYKKSARTVGDVLGKYHPHGDSACYEAMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYTESRLSRFSEVLLSELGQGTVDWQPNFDGTMKEPKMLPARLPHILLNGVTGIAVGMATDIPPHNAREVAAAAVHMIDNPKADLDALMEFVKGPDYPTEAEIITPKAELKKVYRTGRGSIKMRAVWHKENGDIVITSLPHQVSGAKLLEQIATQMRAKKLPMVEDLRDESDHENPTRIVVVPRSNRIDCEQLMNHLFASTDLEKSFRVNLNMLGLDGRPQVKGLVSIISEWLEYRRITVRRRLQHRLDKVTARLHILEGLLAAYLNIDEVIEIIRSEDDPKAELMSRFDLTAIQADAILEIKLRQLAKLEEIKIRGEQDELSKEKEHLEKLLGSERRLNTLIKKELLADAETYGDDRRSPMVERAEAKALTERDLIPSEPITVVLSEKGWIRHAKGHEVDPSTLSYKSGDSYLAHARGKSNQPAIFLGSDGRSYALESHSLPSARSQGEPITGRLNLTPGSNMRQVMMAEDEQLWLMASDAGYGFICKSSDMVSKNKSGKALLTLPENAQVMAPQEIRDIEHDQILAITNEGRMLLFPIKDLPQLGKGKGNKIINIPAARSKSREEFLSYLQVLHDGAQVTLHAGKRKLSLKPSDLDNFRGERGRRGSILPRGLQRVTHIEFSSPATPEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0B4</accession>
    <name>D0Z0B4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal RNA small subunit methyltransferase A</fullName>
            <ecNumber evidence="6">2.1.1.182</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">16S rRNA dimethyladenosine transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">16S rRNA dimethylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rsmA</name>
        <name evidence="6" type="synonym">ksgA</name>
        <name evidence="9" type="ORF">VDA_002977</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>adenosine(1518)/adenosine(1519) in 16S rRNA + 4 S-adenosyl-L-methionine = 4 H(+) + N(6)-dimethyladenosine(1518)/N(6)-dimethyladenosine(1519) in 16S rRNA + 4 S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:19609"/>
            <dbReference type="Rhea" id="RHEA-COMP:10232"/>
            <dbReference type="Rhea" id="RHEA-COMP:10233"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74493"/>
            <dbReference type="EC" id="2.1.1.182"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.182" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301446.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002977"/>
    <dbReference type="EnsemblBacteria" id="EEZ41945">
        <property type="protein sequence ID" value="EEZ41945"/>
        <property type="gene ID" value="VDA_002977"/>
    </dbReference>
    <dbReference type="GeneID" id="57340712"/>
    <dbReference type="eggNOG" id="COG0030">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2030110at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052908">
        <property type="term" value="F:16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00607">
        <property type="entry name" value="16SrRNA_methyltr_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001737">
        <property type="entry name" value="KsgA/Erm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023165">
        <property type="entry name" value="rRNA_Ade_diMease-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020596">
        <property type="entry name" value="rRNA_Ade_Mease_Trfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020598">
        <property type="entry name" value="rRNA_Ade_methylase_Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011530">
        <property type="entry name" value="rRNA_adenine_dimethylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727">
        <property type="entry name" value="PTHR11727"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00398">
        <property type="entry name" value="RrnaAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00650">
        <property type="entry name" value="rADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00755">
        <property type="entry name" value="ksgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01131">
        <property type="entry name" value="RRNA_A_DIMETH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51689">
        <property type="entry name" value="SAM_RNA_A_N6_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="4 6 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 6 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="rADc" evidence="8">
        <location>
            <begin position="25"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="18"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="20"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="270" mass="30657" checksum="95B2C3F1C274B734" modified="2010-01-19" version="1">MSNDVHLGHRARKRFGQNFLTDPFIIDGIVSAINPRSGQNLVEIGPGLGAITEEVGKLVDHFNVIELDRDLAERLRNHPDLGPKLTINEGDAMRFDFTKLIREDAKLRIFGNLPYNISTPLMFHLFTYHKDVQDMHFMLQKEVVNRLAAGPGCKAYGRLTVMAQYYCKVMPVLEVPPESFVPAPKVDSAVVRLTPYETLPFPCTNLKWLDRVCREGFNQRRKTVRNCFKALMTAEQIEALGVNPSDRPENISVEKFVALANWLDANYQAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0K6</accession>
    <name>D0Z0K6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Acetyl-coenzyme A synthetase</fullName>
            <shortName evidence="5">AcCoA synthetase</shortName>
            <shortName evidence="5">Acs</shortName>
            <ecNumber evidence="5">6.2.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Acetate--CoA ligase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Acyl-activating enzyme</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">acsA</name>
        <name evidence="9" type="ORF">VDA_003070</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>acetate + ATP + CoA = acetyl-CoA + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23176"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="PTM">
        <text evidence="5">Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.1" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301749.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003070"/>
    <dbReference type="EnsemblBacteria" id="EEZ42037">
        <property type="protein sequence ID" value="EEZ42037"/>
        <property type="gene ID" value="VDA_003070"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0365">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="141801at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003987">
        <property type="term" value="F:acetate-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016208">
        <property type="term" value="F:AMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019427">
        <property type="term" value="P:acetyl-CoA biosynthetic process from acetate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01123">
        <property type="entry name" value="Ac_CoA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011904">
        <property type="entry name" value="Ac_CoA_lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032387">
        <property type="entry name" value="ACAS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16177">
        <property type="entry name" value="ACAS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02188">
        <property type="entry name" value="Ac_CoA_lig_AcsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0007">Acetylation</keyword>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 5 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACAS_N" evidence="8">
        <location>
            <begin position="24"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding" evidence="6">
        <location>
            <begin position="87"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="7">
        <location>
            <begin position="531"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="region of interest" description="Coenzyme A binding" evidence="5">
        <location>
            <begin position="191"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="311"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="335"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="387"/>
            <end position="389"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="411"/>
            <end position="416"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="500"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="515"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="523"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="526"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="537"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="539"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="542"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="584"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-acetyllysine" evidence="5">
        <location>
            <position position="609"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF16177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ42037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="649" mass="71916" checksum="7445F81A3C4A5AA5" modified="2010-01-19" version="1">MSEAHIFPVNAQLANQAHINDEQYRELYQQSIINPEGFWREQGKILDWITPYSKVKNTSYDPGHVSIKWFEDGELNVSANCIDRHLPTKGDQVAIIWEGDDPNDHAHITYNELHQQVCQFANALKSQGVRKGDVVCLYMPMVAEAAVAMLACTRIGAVHTIVFGGFSPEALAGRIIDSNAKVVITADEGVRGGRAVPLKQNVDQALLHPEVISVEKVVVLKRTGSPVEWFSERDVWWDDITAVASTHCEPEAMNAEDPLFILYTSGSTGKPKGVLHTTGGYLVYTSLTFKYVFDYQEGDIYWCTADVGWITGHSYLVYGPLANGATTLLFEGVPNYPATNRMSQVVDKHQVNILYTAPTAIRALMAKGDEAIVDTSRHSLRIMGSVGEPINPEAWEWYHRTIGDSRCPIVDTWWQTETGGILITPLPGATDLKPGSATRPFFGVQPALVDNLGNILPGATEGNLVMLDSWPGQMRTLWGDHERFEQTYFSTFAGMYFTGDGARRDEDDYYWITGRVDDVLNISGHRMGTAEIESALVAFNKIAEAAVVGVPHEIKGQAIYAYITLNDGEIPSAQLHKEVKDWVRKEIGPIATPDFLHWTDALPKTRSGKIMRRILRKIATGDTSNLGDTSTLADPSVVEKLIAEKQQLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0L4</accession>
    <name>D0Z0L4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="15">PTS system maltose and glucose-specific IIBC component</fullName>
            <ecNumber evidence="15">2.7.1.69</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">VDA_003078</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.7.1.69" evidence="15"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003078"/>
    <dbReference type="EnsemblBacteria" id="EEZ42045">
        <property type="protein sequence ID" value="EEZ42045"/>
        <property type="gene ID" value="VDA_003078"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1263">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1264">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103111">
        <property type="term" value="F:D-glucosamine PTS permease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008982">
        <property type="term" value="F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00212">
        <property type="entry name" value="PTS_IIB_glc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036878">
        <property type="entry name" value="Glu_permease_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018113">
        <property type="entry name" value="PTrfase_EIIB_Cys"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003352">
        <property type="entry name" value="PTS_EIIC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013013">
        <property type="entry name" value="PTS_EIIC_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001996">
        <property type="entry name" value="PTS_IIB_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011301">
        <property type="entry name" value="PTS_Mal/Glc-sp_IIBC_component"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00367">
        <property type="entry name" value="PTS_EIIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02378">
        <property type="entry name" value="PTS_EIIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55604">
        <property type="entry name" value="SSF55604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00826">
        <property type="entry name" value="EIIB_glc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02004">
        <property type="entry name" value="PTS-IIBC-malX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51098">
        <property type="entry name" value="PTS_EIIB_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01035">
        <property type="entry name" value="PTS_EIIB_TYPE_1_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51103">
        <property type="entry name" value="PTS_EIIC_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0598">Phosphotransferase system</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="5 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="17"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="57"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="101"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="214"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="243"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="272"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="324"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="domain" description="PTS EIIC type-1" evidence="14">
        <location>
            <begin position="1"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="PTS EIIB type-1" evidence="13">
        <location>
            <begin position="367"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphocysteine intermediate; for EIIB activity" evidence="11">
        <location>
            <position position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEZ42045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="447" mass="47089" checksum="A3237FB8A236887C" modified="2010-01-19" version="1">MFAVAIPLGLAREEKGVAAFAGFVGYAALNLSVNFYLTVAGVIGNKEQEAAYGVKSVLGIESIDTGILGAVIVGIIVAKLHARFYTFKMPDALAFFGGARFVPIISALSLGLVGLVVPLIWPYFAAGIDGVGSLISHAGPFGPFLFGTGERLLLPFGLHHILVALIRFTEAGGTLDVCGNSVSGALNIFYAELSCGTTNGFSGSATAFLSQGKMPVFLGGLPGAALAMYHCARKENRSKVKALLLSGVVACVIGGITEPLEFLFLFVAPALYVVHAFLTGLGFMLMGLLGVTIGNTDGNIIDFLIFGVLQGTATKWYLVPMVAAVWFVVYYSVFRFAITRFNLKTPGREAEVKDELTFAVTGEKNSGYKGAAILAALGGAENIQSLDNCITRLRLSVADMSLVNDVVLKANGAIGVVKLDEHNLQVVIGPQVHMVKNEIQSLMPAQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0M8</accession>
    <name>D0Z0M8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 8">DNA-directed RNA polymerase subunit beta</fullName>
            <shortName evidence="6">RNAP subunit beta</shortName>
            <ecNumber evidence="6 8">2.7.7.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">RNA polymerase subunit beta</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Transcriptase subunit beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rpoB</name>
        <name evidence="16" type="ORF">VDA_003092</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 8">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6 8">
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="6 8">The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the RNA polymerase beta chain family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="6 8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301835.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003092"/>
    <dbReference type="EnsemblBacteria" id="EEZ42059">
        <property type="protein sequence ID" value="EEZ42059"/>
        <property type="gene ID" value="VDA_003092"/>
    </dbReference>
    <dbReference type="GeneID" id="57340429"/>
    <dbReference type="eggNOG" id="COG0085">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="9601at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032549">
        <property type="term" value="F:ribonucleoside binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00653">
        <property type="entry name" value="RNA_pol_B_RPB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01321">
        <property type="entry name" value="RNApol_bact_RpoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042107">
        <property type="entry name" value="DNA-dir_RNA_pol_bsu_ext_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019462">
        <property type="entry name" value="DNA-dir_RNA_pol_bsu_external_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015712">
        <property type="entry name" value="DNA-dir_RNA_pol_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007120">
        <property type="entry name" value="DNA-dir_RNAP_su2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037033">
        <property type="entry name" value="DNA-dir_RNAP_su2_hyb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010243">
        <property type="entry name" value="RNA_pol_bsu_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007121">
        <property type="entry name" value="RNA_pol_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007644">
        <property type="entry name" value="RNA_pol_bsu_protrusion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007642">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037034">
        <property type="entry name" value="RNA_pol_Rpb2_2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007645">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007641">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014724">
        <property type="entry name" value="RNA_pol_RPB2_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20856">
        <property type="entry name" value="PTHR20856"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04563">
        <property type="entry name" value="RNA_pol_Rpb2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04561">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04565">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10385">
        <property type="entry name" value="RNA_pol_Rpb2_45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00562">
        <property type="entry name" value="RNA_pol_Rpb2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04560">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02013">
        <property type="entry name" value="rpoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01166">
        <property type="entry name" value="RNA_POL_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 6 8" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="3 6 8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RNA_pol_Rpb2_1" evidence="13">
        <location>
            <begin position="26"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_Rpb2_2" evidence="12">
        <location>
            <begin position="151"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_Rpb2_2" evidence="12">
        <location>
            <begin position="349"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_Rpb2_3" evidence="14">
        <location>
            <begin position="513"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_Rpb2_45" evidence="15">
        <location>
            <begin position="591"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_Rpb2_6" evidence="10">
        <location>
            <begin position="717"/>
            <end position="1263"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_Rpb2_7" evidence="11">
        <location>
            <begin position="1265"/>
            <end position="1339"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="936"/>
            <end position="963"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="1004"/>
            <end position="1031"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF04560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF04561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF04563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF04565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF10385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EEZ42059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="1341" mass="149414" checksum="FD4779A8A8381EED" modified="2010-01-19" version="1">MVYSYTEKKRIRKDFGKRPQVLDAPYLLSIQLDSFQKFIEQDPEGHYGLEAAFRSVFPIQSYNGNSELQYVSYRLGEPVFDVKECQIRGVTYSAPLRVKLRLVMYDKDAPAGTVKDIKEQEVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSDKGKTHSSGKVLYNARVIPYRGSWLDFEFDPKDSVFVRIDRRRKLPASIILRALGYTTDQILDMFFEKVKFEVQGKSLVMELVPDRLRGETASFDIEANGTVYVEKGRRITARHIRQLAKDGVDHIEVPVEYIVGKVAAKDYVNEATGELIAAANQELSLESLALLSQAGHKSIEVLFTNDLDHGPYMSDTLRIDSTTDRLSALVEIYRMMRPGEPPTREAAEQLFESLFFSEERYDLSAVGRMKFNSSLLRDETTGPGTLDNQDIIDVMRKLIDIRNGKGEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVKERLSLGDLDAIMPQDLINAKPISAAVKEFFGSSQLSQFMDQNNPLSEVTHKRRISALGPGGLTRERAGFEVRDVHATHYGRLCPIETPEGPNIGLINSLSVFARCNPYGFLETPYRKVVDGKVSEEIEYLSAIEEGQYVIAQANAALNEDGSFADELITARQKGDSGLHPRDHVQYMDVATNQVVSVAASLIPFLEHNDANRALMGANMQRQAVPTIRADKPLVGTGIERQIGVDSGVTAVAKRGGQVQFVDASRIVIKVNDDELIPGEAGIDIYNLTKYTRSNQNTCINQRPCVMVGEPVARGDVLADGPSTDLGELALGQNMRIAFMPWNGYNFEDSILVSERVVQEDRLTTIHIQELSCVARDTKLGAEEITADIPNVGEAALSKLDESGIVYIGAEVKGGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPGSVTGTVIDVQVFTRDGVEKDKRALEIEEMQLKEAKKDLTEEFQILEGGLLARVRTLLLASGYSEDKIASMDREKLFAQTLDDEALQNQLEQLAEQYDELKAEFDKKFETKRRKITQGDDLAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVISKINPVEDMPYDEKGQTVDIVLNPLGVPSRMNIGQILETHLGLAAKGIGDKINEMMKQQQELHKIREFLQRVYDLGDTRQKVDIALLSDEEVLTLAQNLRKGLPIATPVFDGAPEASIKELLQLGDLPSSGQLQLFDGRTGNPFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGDHRMEPGMPESFNVLLKEIRSLGINIELEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0Q4</accession>
    <name>D0Z0Q4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Type II secretion system protein H</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">General secretion pathway protein H</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">VDA_003118</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the GSP H family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301914.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003118"/>
    <dbReference type="EnsemblBacteria" id="EEZ42085">
        <property type="protein sequence ID" value="EEZ42085"/>
        <property type="gene ID" value="VDA_003118"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2165">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1990712at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022346">
        <property type="entry name" value="T2SS_GspH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002416">
        <property type="entry name" value="T2SS_protein-GspH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12019">
        <property type="entry name" value="GspH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00885">
        <property type="entry name" value="BCTERIALGSPH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01708">
        <property type="entry name" value="typeII_sec_gspH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0488">Methylation</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="GspH" evidence="13">
        <location>
            <begin position="44"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF12019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEZ42085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="193" mass="22268" checksum="3A2DFE1E71E2CCF5" modified="2010-01-19" version="1">MSLKRAAGFTLIEIMLVMVLLALSSVAVIMTMPKNQNDEAKNEAVRFYQLSQLLSEDAMLTGRDYGIDVSAHRYHFVELTQDGWQEIKEKTKYYNQVETPKAITLVYEKGGEWQKKDRLFKQDKLFSQEDLFEKDPDEKKRKPPQIVVMASGEITPFTVSFETSGEHQYWRVVATEIGDVKLLEPGQELEIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0R3</accession>
    <name>D0Z0R3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AsmA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003127</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301944.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003127"/>
    <dbReference type="EnsemblBacteria" id="EEZ42094">
        <property type="protein sequence ID" value="EEZ42094"/>
        <property type="gene ID" value="VDA_003127"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2911">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="312440at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007844">
        <property type="entry name" value="AsmA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05170">
        <property type="entry name" value="AsmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AsmA" evidence="1">
        <location>
            <begin position="154"/>
            <end position="590"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="651" mass="74537" checksum="8E0EC9BD50BF1DB1" modified="2010-01-19" version="1">MRILAKWIVTLIILLLLLITVTLALLQSRFATPIINRVATYSPYPIQFQQVSYSLKQPWHMTFIGPSWSGLEQTRPIAQRVELWWSANLAHPRQFDSVLVAGINYREPSQFTLPAFAAKRLALTDVSLLTPNFVMKSGKVELNNWHSSAQYPWWQSFQGEFIVSADRIYYHQQELNQLLINGRHSTTDKWLFDGLSFTWQHAQVSGQAIYYPQEKRLTLAQFTVQGLQLQQDSVLYSLNDTLKPYINTLDIERFDLLESSVELKQLTANGVNLSLENITWPKNLWQQQGQISLSANNIQWQHITFDNPILDMQLQPDQLIISGLSSQLLSGYINLNGTITPTTLSLKKVIINGIKWILPNGWLTQFQQLNLPWQQIEIQHLDTSNLLLTSTDPDWLIQMAGLDITGDKLTWHHKDFWQLWQGELAVSSSFSSINQIILNDPIMEMSSDQGNWQLKRAVLPFKDGLLRATGKIELSQSGRPWQLSINGDSVPTRLLHAWLKLPLPITGVMDNQIQLHGLSSDKAALDYSLSGHIYTQWRDNQFIASAQQYFQDWQQAQWQPKAMAKITKDTKPHAIDIAPLQLQLNRGIASVSPWHWQSPSLSGTLTGQWDFTQRETDLQLNLIQDCQQLNRHWRQDKSQVTTASSCTGSNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z104</accession>
    <name>D0Z104_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Site-specific recombinase phage integrase family domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_003218</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302194.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003218"/>
    <dbReference type="EnsemblBacteria" id="EEZ42185">
        <property type="protein sequence ID" value="EEZ42185"/>
        <property type="gene ID" value="VDA_003218"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0582">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1927753at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ42185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="803" mass="91460" checksum="D9310BC889D82955" modified="2010-01-19" version="1">MLSVAIDNSSITNRIESIVRDHSLLNDLSAETLEEIINFSVANDDYRVLDIITNIHTCIYNYDDRQPEWLESSFPENKWVLTFGKTPKTIHWDTVYLDDGKKLTDKKHQKLLNSFKYWITAADNPLENGGKIISPITACHKVNKVIALINAVLLHSKELKLAKYHLLNVNDDFWLNILTKYAEHGNFQGVYEIDKHTNVFLNNASQSISDTDAQTFKENFPYVTQDIAQDESFLFLAEREKACAWLFEQGYYQSGGAIKYTGSGAVLGKLLFKGKMLYHDINIPNFAELHLKAPRRNSEYRAVENKDTSTGTNQQTISVYIEAIRLIHTNLEREDAASPLILSERVSSGHISQLVSLKKAGRTRTLPPTFVFNLIRQCYEFAKEHLPIEEGAVTLLDETLTLLSKARSKSAAKHSNTLRPHQQNLTWNEELHREMSVTERGYWFQTEAINCLSREYLKKGVKQIQAFAESVESRFERIRANESLFDLFSVLQGAIQVLVGAIMARRQDELIKLKSHGNLSPDVSPFSEAGAKTEYNLIFKVKKTGSKGVNATIERPIPLSIARYIWQLEQFNIKASELELCKGKLSLFNNLNSKRSQLSQVIHKSYNAHLDALCDYLETDLVEYDNGEYRRNYVRQHQLRRFFAMAFFWSKGTDGMDALRWMLGHSDLEHLYHYISESETGAVLNGAKASVIVRGVVDSTSELAKLDGIEEVRKIIAERLTGDSSTPITIESVSEAAEDYADESYLTVPHISQLQKEQDIEIEVIQLLEEGRITLEPEFFTIEDDDGNTTQTFNLILKISDLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z118</accession>
    <name>D0Z118_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">ATP synthase subunit alpha</fullName>
            <ecNumber evidence="14">7.1.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">ATP synthase F1 sector subunit alpha</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">F-ATPase subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">atpA</name>
        <name evidence="18" type="ORF">VDA_003232</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 14">Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:57720"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.1.2.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="13">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="14">Cell membrane</location>
            <topology evidence="14">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.</text>
    </comment>
    <dbReference type="EC" id="7.1.2.2" evidence="14"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302234.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003232"/>
    <dbReference type="EnsemblBacteria" id="EEZ42199">
        <property type="protein sequence ID" value="EEZ42199"/>
        <property type="gene ID" value="VDA_003232"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0056">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="837522at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18113">
        <property type="entry name" value="ATP-synt_F1_alpha_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01132">
        <property type="entry name" value="F1_ATPase_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.150.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01346">
        <property type="entry name" value="ATP_synth_alpha_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023366">
        <property type="entry name" value="ATP_synth_asu-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000793">
        <property type="entry name" value="ATP_synth_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038376">
        <property type="entry name" value="ATP_synth_asu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033732">
        <property type="entry name" value="ATP_synth_F1_a"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005294">
        <property type="entry name" value="ATP_synth_F1_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036121">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00306">
        <property type="entry name" value="ATP-synt_ab_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50615">
        <property type="entry name" value="SSF50615"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00962">
        <property type="entry name" value="atpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 14" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="6 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 14" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10 14" id="KW-0139">CF(1)</keyword>
    <keyword evidence="5 14" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="18" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 14" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 14" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 14" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATP-synt_ab_N" evidence="17">
        <location>
            <begin position="29"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-synt_ab" evidence="15">
        <location>
            <begin position="149"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-synt_ab_C" evidence="16">
        <location>
            <begin position="382"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="169"/>
            <end position="176"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Required for activity" evidence="14">
        <location>
            <position position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00026013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF02874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EEZ42199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="513" mass="55686" checksum="9EA2623D9D005D9B" modified="2010-01-19" version="1">MQLNSTEISDLIKQRIESFNVVSEARNEGTIVSVSDGIIRIHGLADVMQGEMIELPNGRFALALNLERDSVGAVVMGPYLDLQEGMKVTGTGRILEVPVGPELLGRVVNTLGEPIDGKGPINAKTFSPVEVIAPGVIDRKSVDQPVQTGYKAVDSMIPIGRGQRELIIGDRQTGKTAMAIDAIINQKNSGIYSVYVAIGQKASTIANVVRKLEEHGALENTIIVVASASEAAALQYLAPYSGCAMGEYFRDRGEDALIVYDDLSKQAVAYRQISLLLRRPPGREAFPGDVFYLHSRLLERAARVNEHYVEKFTNGEVTGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLQTELFNAGIRPAVDPGISVSRVGGAAQTKVIKKLSGGIRTALAQYRELAAFAQFSSDLDDATKKQLDHGQKVTELMKQKQYAPMSVFEQAIVIFSAEKGYLNDVELTKLADFEAALLSYAKGQFAELVAQIDETGAWNDEIEAQFTKLLEDFKATQTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z126</accession>
    <name>D0Z126_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 11">Glucose-inhibited division protein A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">mnmG</name>
        <name evidence="11" type="synonym">gidA</name>
        <name evidence="14" type="ORF">VDA_003240</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 11">NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="9 11">Homodimer. Heterotetramer of two MnmE and two MnmG subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the MnmG family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302259.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003240"/>
    <dbReference type="EnsemblBacteria" id="EEZ42207">
        <property type="protein sequence ID" value="EEZ42207"/>
        <property type="gene ID" value="VDA_003240"/>
    </dbReference>
    <dbReference type="GeneID" id="57340352"/>
    <dbReference type="eggNOG" id="COG0445">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="146811at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00129">
        <property type="entry name" value="MnmG_GidA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004416">
        <property type="entry name" value="MnmG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002218">
        <property type="entry name" value="MnmG-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020595">
        <property type="entry name" value="MnmG-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026904">
        <property type="entry name" value="MnmG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044920">
        <property type="entry name" value="MnmG_C_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040131">
        <property type="entry name" value="MnmG_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11806">
        <property type="entry name" value="PTHR11806"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11806:SF0">
        <property type="entry name" value="PTHR11806:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01134">
        <property type="entry name" value="GIDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13932">
        <property type="entry name" value="GIDA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00136">
        <property type="entry name" value="gidA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01280">
        <property type="entry name" value="GIDA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01281">
        <property type="entry name" value="GIDA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 11" id="KW-0274">FAD</keyword>
    <keyword evidence="5 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8 11" id="KW-0520">NAD</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="GIDA" evidence="12">
        <location>
            <begin position="8"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="GIDA_C" evidence="13">
        <location>
            <begin position="403"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="13"/>
            <end position="18"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="273"/>
            <end position="287"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="370"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF13932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEZ42207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="629" mass="69990" checksum="D313C0EE8B5AB5E2" modified="2010-01-19" version="1">MFYQDNFDVIVVGGGHAGTEAALAAARMGQKTLLLTHNIDTLGQMSCNPAIGGIGKGHLVKEVDALGGLMARAIDKGGIQFRTLNSSKGPAVRATRAQADRALYKAAVREALENQPNLMLFQQAVTDLIVEQDRVVGAVTEMGLKFRAKAVVLTVGTFLGGRIHIGLENYNGGRAGDPPSIALAHRLRELPFRVSRLKTGTPPRIDARTVDFSVLEKQFGDNPTPVFSFMGKQSDHPRQIPCFITHTNERTHDVIRNNLDRSPMYAGVIEGVGPRYCPSIEDKVMRFADKNSHQIFIEPEGLTTHELYPNGISTSLPFDVQMQIVRSMKGFENADIVRPGYAIEYDFFDPRDLKQTFETKFMAGLFFAGQINGTTGYEEAAAQGLLAGMNAALCAQGKDGWSPRRDQAYMGVLIDDLSTIGTKEPYRMFTSRAEYRLLLREDNADLRLTEMGRQFGLVDDERWARFNQKIENMEQERQRLKDIWINPNSAQVDELNKILKTPIVREASGEDLLRRPEVTYDMLTAIETFGPALEDTQASEQVEIQVKYQGYIDRQKDEVEKSLRHEKTKLPFDLDYSVVKGLSNEVIAKLNDAKPETVGMASRISGVTPAAISLLLVYLKKQGLLKKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z153</accession>
    <name>D0Z153_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hypothetical transcriptional regulator TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_003267</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003267"/>
    <dbReference type="EnsemblBacteria" id="EEZ42234">
        <property type="protein sequence ID" value="EEZ42234"/>
        <property type="gene ID" value="VDA_003267"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032551">
        <property type="entry name" value="BscR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023772">
        <property type="entry name" value="DNA-bd_HTH_TetR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16295">
        <property type="entry name" value="TetR_C_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01081">
        <property type="entry name" value="HTH_TETR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="16"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ42234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="202" mass="23164" checksum="0495CCE7DAD5296D" modified="2010-01-19" version="1">MNVHSSINQRSDITMNDKKERILQATEMLLAKHGFHGLSMQKVAQEAGVAAGTIYRYFADKDDLLYQLHDHILGYVAQKIVQDLNDDMSLKQQFRTIWLNIWNMAINGEVLLINQGQFEHLPRRNSSEQRLREKKLFAKIDQMFDQGKEVGLFKRLDNDILSVLSLEPSACLARKKMNGMLDVSPQQLEAAIEAAWDAIVQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z167</accession>
    <name>D0Z167_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ubiquinone biosynthesis accessory factor UbiJ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ubiJ</name>
        <name evidence="3" type="ORF">VDA_003281</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the UbiJ family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302375.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003281"/>
    <dbReference type="EnsemblBacteria" id="EEZ42248">
        <property type="protein sequence ID" value="EEZ42248"/>
        <property type="gene ID" value="VDA_003281"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3165">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1959286at2"/>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032150">
        <property type="term" value="P:ubiquinone biosynthetic process from chorismate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02215">
        <property type="entry name" value="UbiJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003033">
        <property type="entry name" value="SCP2_sterol-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036527">
        <property type="entry name" value="SCP2_sterol-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038989">
        <property type="entry name" value="UbiJ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38693">
        <property type="entry name" value="PTHR38693"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02036">
        <property type="entry name" value="SCP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55718">
        <property type="entry name" value="SSF55718"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="domain" description="SCP2" evidence="2">
        <location>
            <begin position="15"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ42248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="200" mass="22235" checksum="75F439A79C1B9196" modified="2010-01-19" version="1">MPIDVFITGTVETALNQLLKEDADSGRRLNRLRGKVISVTFNELNKTLFFVFSQQIDVLAAFEGEVDCQLALNLAVLPQLRQSSQLTQLIKADKLMLSGDIQLAQQFATLLGGLKPDVEEKLSHYTGDIVAHTLVSSVKGGAEQVKRILTRRQQQLAETLTEEWKVVPSPLEIAYFADQVDDVKSATARLEARLNRLLES</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1A6</accession>
    <name>D0Z1A6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cytochrome-c oxidase</fullName>
            <ecNumber evidence="3">7.1.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Cytochrome aa3 subunit 3</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Cytochrome c oxidase polypeptide III</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">VDA_003320</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the cytochrome c oxidase subunit 3 family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.9" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302486.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003320"/>
    <dbReference type="EnsemblBacteria" id="EEZ42287">
        <property type="protein sequence ID" value="EEZ42287"/>
        <property type="gene ID" value="VDA_003320"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1845">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1502742at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004129">
        <property type="term" value="F:cytochrome-c oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019646">
        <property type="term" value="P:aerobic electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01665">
        <property type="entry name" value="Cyt_c_Oxidase_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024791">
        <property type="entry name" value="Cyt_c/ubiquinol_Oxase_su3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033945">
        <property type="entry name" value="Cyt_c_oxase_su3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000298">
        <property type="entry name" value="Cyt_c_oxidase-like_su3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035973">
        <property type="entry name" value="Cyt_c_oxidase_su3-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013833">
        <property type="entry name" value="Cyt_c_oxidase_su3_a-hlx"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11403">
        <property type="entry name" value="PTHR11403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00510">
        <property type="entry name" value="COX3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81452">
        <property type="entry name" value="SSF81452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50253">
        <property type="entry name" value="COX3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="157"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="187"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="224"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="271"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="COX3" evidence="11">
        <location>
            <begin position="6"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00031400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ42287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="291" mass="32691" checksum="11EE82B37C7FD47D" modified="2010-01-19" version="1">MDKSPQQPSYYVPDSSIWPIVGAVALFLIALGAGTTVGNLLAGNGPWILLTGLGILLIMLFGWFRDVIIESMQGLYSSQLDRSFRQGMSWFIFSEVMFFVAFFGALFYARMIAVPWLGGASNNAMTHAVLWPDFVAIWPLETTPDGRTTQAMGPLGLPLYNTLILLTSSVTIHIAHMAMEQNRRPRVILFLLLTVLLGALFVYLQGVEYLHAYQEMGLTLDAGIYGNTFFMLTGFHGLHVTLGAVLLFIVWCRVMMGHFSAHKHFAFQAGVWYWHFVDVVWLCLFVFVYIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1C0</accession>
    <name>D0Z1C0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA (guanosine(18)-2'-O)-methyltransferase</fullName>
            <ecNumber evidence="4">2.1.1.34</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">tRNA [Gm18] methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">trmH</name>
        <name evidence="7" type="ORF">VDA_003334</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>guanosine(18) in tRNA + S-adenosyl-L-methionine = 2'-O-methylguanosine(18) in tRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:20077"/>
            <dbReference type="Rhea" id="RHEA-COMP:10190"/>
            <dbReference type="Rhea" id="RHEA-COMP:10192"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74445"/>
            <dbReference type="EC" id="2.1.1.34"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.34" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302512.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003334"/>
    <dbReference type="EnsemblBacteria" id="EEZ42301">
        <property type="protein sequence ID" value="EEZ42301"/>
        <property type="gene ID" value="VDA_003334"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0566">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1422015at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009020">
        <property type="term" value="F:tRNA (guanosine-2'-O-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052665">
        <property type="term" value="F:tRNA (uracil-2'-O-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002938">
        <property type="term" value="P:tRNA guanine ribose methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd18092">
        <property type="entry name" value="SpoU-like_TrmH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02060">
        <property type="entry name" value="tRNA_methyltr_TrmH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022724">
        <property type="entry name" value="rRNA_MeTrfase_SpoU_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033671">
        <property type="entry name" value="TrmH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43453">
        <property type="entry name" value="PTHR43453"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12105">
        <property type="entry name" value="SpoU_methylas_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 4 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="1 4" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="SpoU_methylase" evidence="5">
        <location>
            <begin position="20"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="SpoU_methylas_C" evidence="6">
        <location>
            <begin position="163"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ42301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="236" mass="26298" checksum="6407DDDEE2FD5516" modified="2010-01-19" version="1">MTPERFERISQVLATRQPDLTVCLEQVHKPNNVSAIIRTADAVGVHKVHAVWQAEQLRLHSHTSAGSRNWVELETHANITDAVHAMKAQGMQVLATNLSERAVDFREIDYTKPTAIILGGEKHGITPEALALADQDIIIPMVGMVQSLNVSVASALILYEAQRQRQNAGMYQRTETLLPDEVVHRILFERGHPVLANVAKRKGLPYPELDAEGQIVADDAWWATMQAVEPKKNKQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1C1</accession>
    <name>D0Z1C1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Guanosine-3',5'-bis(diphosphate) 3'-diphosphatase</fullName>
            <ecNumber evidence="3">3.1.7.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_003335</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>guanosine 3',5'-bis(diphosphate) + H2O = diphosphate + GDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14253"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:77828"/>
            <dbReference type="EC" id="3.1.7.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; ppGpp biosynthesis; ppGpp from GDP: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the relA/spoT family.</text>
    </comment>
    <dbReference type="EC" id="3.1.7.2" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302514.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003335"/>
    <dbReference type="EnsemblBacteria" id="EEZ42302">
        <property type="protein sequence ID" value="EEZ42302"/>
        <property type="gene ID" value="VDA_003335"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0317">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="204079at2"/>
    <dbReference type="UniPathway" id="UPA00908">
        <property type="reaction ID" value="UER00886"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008728">
        <property type="term" value="F:GTP diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008893">
        <property type="term" value="F:guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015970">
        <property type="term" value="P:guanosine tetraphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05399">
        <property type="entry name" value="NT_Rel-Spo_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01668">
        <property type="entry name" value="TGS_RSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004811">
        <property type="entry name" value="RelA/Spo_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045600">
        <property type="entry name" value="RelA/SpoT_AH_RIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007685">
        <property type="entry name" value="RelA_SpoT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033655">
        <property type="entry name" value="TGS_RelA/SpoT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13291">
        <property type="entry name" value="ACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19296">
        <property type="entry name" value="DUF5913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04607">
        <property type="entry name" value="RelA_SpoT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02824">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00954">
        <property type="entry name" value="RelA_SpoT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="SSF81271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00691">
        <property type="entry name" value="spoT_relA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HD" evidence="6">
        <location>
            <begin position="45"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="TGS" evidence="7">
        <location>
            <begin position="387"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="domain" description="ACT" evidence="5">
        <location>
            <begin position="627"/>
            <end position="701"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00024273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00024329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ42302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="701" mass="79105" checksum="8FC9F40FD0612D2B" modified="2010-01-19" version="1">MYLFDSLKEVAIEYLPEPQIEALRQAYLVARDAHEGQTRSSGEPYIIHPIAVARILAEMRLDYETLMAALLHDVIEDTEVTKDDLATRFGDTVAELVDGVSKLDKLKFRDRKEAQAENFRKMIMAMAHDIRVILIKLADRTHNMRTLGALRPDKRRRIARETLEIFSPLAHRLGIHNIKTELEELGFEALYPNRYRVLKNVVAAARGNRKEMINKIHAEIEGRLVDAGIDAQVLGREKNLYSIYNKMKNKELRFHSIMDIYAFRVLVKDIDTCYRVLGQVHNLYKPRPSRMKDYIAIPKANGYQSLHTSLVGPHGVPVEVQIRTEDMDQMADKGVAAHWAYKKDGAGSSTTAQLKAQRWMQSLIELQQSAGNSFEFIENVKSDLCPDEIYVFTPKGRIVELPMGATAVDFAYAVHTDVGNSCVGCRVERQPYPLSKPLKNGQTIDIITAPGARPNAAWLNYVVTSRARTKIRQVLKTMRREESITLGRRLLNHALGGVKLDELPSENIDKVLSDLRIESTDELLTEIGLGELMSVVIARRLLGNADELNAKDNHHRLPIQGADGILLTYANCCHPIPGDPIVAHVSPGRGLVIHREECANIRGHRKEPDKYMAVEWSDDIEQEFVTNLKVDMHNHQGALADLTNTIAATGSNIQGLATEEKDGRLYTITVRLTTKSRVHLASIMRRIRVMPNVVRVSRQKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1C6</accession>
    <name>D0Z1C6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">Orotate phosphoribosyltransferase</fullName>
            <shortName evidence="4">OPRT</shortName>
            <shortName evidence="4">OPRTase</shortName>
            <ecNumber evidence="2 4">2.4.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">pyrE</name>
        <name evidence="6" type="ORF">VDA_003340</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>diphosphate + orotidine 5'-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + orotate</text>
            <dbReference type="Rhea" id="RHEA:10380"/>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57538"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="EC" id="2.4.2.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1 4">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.10" evidence="2 4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302524.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003340"/>
    <dbReference type="EnsemblBacteria" id="EEZ42307">
        <property type="protein sequence ID" value="EEZ42307"/>
        <property type="gene ID" value="VDA_003340"/>
    </dbReference>
    <dbReference type="GeneID" id="57340215"/>
    <dbReference type="eggNOG" id="COG0461">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1280396at2"/>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00119"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004588">
        <property type="term" value="F:orotate phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01208">
        <property type="entry name" value="PyrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023031">
        <property type="entry name" value="OPRT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004467">
        <property type="entry name" value="Or_phspho_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00336">
        <property type="entry name" value="pyrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 4" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran" evidence="5">
        <location>
            <begin position="46"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Orotate binding" evidence="4">
        <location>
            <begin position="34"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="5-phosphoribose 1-diphosphate binding" evidence="4">
        <location>
            <begin position="72"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="5-phosphoribose 1-diphosphate binding" evidence="4">
        <location>
            <begin position="124"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="26"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>orotate</name>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>orotate</name>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ42307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="213" mass="23275" checksum="4DA5864247FD0303" modified="2010-01-19" version="1">MKAYQRQFIEFALEKGVLKFGEFTLKSGRKSPYFFNAGLFNTGRDLARLGRFYAEALVDAGIEFDVLFGPAYKGIPIATTTAVALADQHDIDTPYCFNRKEAKDHGEGGNLVGSPLEGRIMLVDDVITAGTAIRESMEIIKANGADLAGVLVAIDRQEKGKSELSAIQEVERDFGCAVISIVSLGDVVRYLEEQPGMTDHLAAVQAYREQYGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1D8</accession>
    <name>D0Z1D8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">3-deoxy-D-manno-octulosonic acid kinase</fullName>
            <shortName evidence="7">Kdo kinase</shortName>
            <ecNumber evidence="5 7">2.7.1.166</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">kdkA</name>
        <name evidence="9" type="ORF">VDA_003352</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>alpha-Kdo-(2-&gt;6)-lipid IVA + ATP = 4-O-phospho-alpha-Kdo-(2-&gt;6)-lipid IVA + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:28506"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:60364"/>
            <dbReference type="ChEBI" id="CHEBI:61589"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.166"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 7">Bacterial outer membrane biogenesis; LPS core biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell inner membrane</location>
            <topology evidence="7">Peripheral membrane protein</topology>
            <orientation evidence="7">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 7">Belongs to the protein kinase superfamily. KdkA/RfaP family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.166" evidence="5 7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302553.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003352"/>
    <dbReference type="EnsemblBacteria" id="EEZ42319">
        <property type="protein sequence ID" value="EEZ42319"/>
        <property type="gene ID" value="VDA_003352"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3642">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1643499at2"/>
    <dbReference type="UniPathway" id="UPA00958"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009244">
        <property type="term" value="P:lipopolysaccharide core region biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00521">
        <property type="entry name" value="KDO_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022826">
        <property type="entry name" value="KDO_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0448">Lipopolysaccharide biosynthesis</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="15"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ42319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="234" mass="27184" checksum="9A8F4989F30B07B2" modified="2010-01-19" version="1">MQIIQTKQQYICYNPELLTETPEMAFSSEFWQQQNKIIGSAQGRGTTWFVQGEKLAMALRHYRRGGLFGKLVADSYLFSCWDKTRSVAEFSLLNHLIAHQVNVPKPVAARAVRLGWFRYQADILVEKIANSRDLVGILGQETLSQQVWFDVGAMIKRMHDAGVCHTDLNCHNILLDDHKTVWIIDFDKCYRLEGANWQEKNLARLHRSFIKEQGKRGILFNEDNWQWLLQGYHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1E5</accession>
    <name>D0Z1E5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative capsular polysaccharide biosynthesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_003359</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302567.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003359"/>
    <dbReference type="EnsemblBacteria" id="EEZ42326">
        <property type="protein sequence ID" value="EEZ42326"/>
        <property type="gene ID" value="VDA_003359"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="635734at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="25"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="174"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ42326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="359" mass="40023" checksum="198CDD7F46AF33B2" modified="2010-01-19" version="1">MKILIASSYKHAWNSVRPEAEMFIEMVKQGHEVTIATQGDADYVARFRDCGVKVIDCYPSKKICLKTIKMLHHELKDGNYDICYGFNSKTIPNLAFASIGTKAKLVTYRGTTGGLYRHDPSAYLTHLHPKVKGVVCVSNAVRDDVRKHVWHNKDQVVTIYKGHQLAWYQVPQTERSEFGLTDDHIIAVCAAHVRPSKGISVLIEATHHINNPNFHLLLVGSGFEPHFDEIKQSPMAERIHLVGHRQDVPSIMAMADFQVQPSISGEGLPRTIVEAMANGTTSVVTTTGGSPELVDDGQTGFVVPTGDAKAFAEAMNKLIHDRSKIEQFSIAAKEKLDREFNAAMTVKHHIEFFELLLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1K9</accession>
    <name>D0Z1K9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_003423</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ42390">
        <property type="protein sequence ID" value="EEZ42390"/>
        <property type="gene ID" value="VDA_003423"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1765">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003718">
        <property type="entry name" value="OsmC/Ohr_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036102">
        <property type="entry name" value="OsmC/Ohrsf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02566">
        <property type="entry name" value="OsmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82784">
        <property type="entry name" value="SSF82784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ42390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="93" mass="9771" checksum="6C9C6AB108C17E45" modified="2010-01-19" version="1">MAAGGCSSVDVVEGLKSAGQKITACEAQVSATRREQAPRLFTQANLHFVVTGVDLDEALVAQTVANSLEKYCSVCLMLGKGVELTHSYQVVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1L3</accession>
    <name>D0Z1L3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glutathione-regulated potassium-efflux system ancillary protein KefG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003427</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302691.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003427"/>
    <dbReference type="EnsemblBacteria" id="EEZ42394">
        <property type="protein sequence ID" value="EEZ42394"/>
        <property type="gene ID" value="VDA_003427"/>
    </dbReference>
    <dbReference type="GeneID" id="57340120"/>
    <dbReference type="eggNOG" id="COG2249">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1143659at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003680">
        <property type="entry name" value="Flavodoxin_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02525">
        <property type="entry name" value="Flavodoxin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin_2" evidence="1">
        <location>
            <begin position="8"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="193" mass="22184" checksum="FE1D1847B185CA00" modified="2010-01-19" version="1">MDYQGKLTILVIYAHPDPQQSVANQVMLDHIADLPHVTVHDLYAAYPDFFIDCHQERALVEMHDIIIFQHPLYMYSCPALLKEWIDVVLSKGFAHGDGIATKGKYWLSVITTGGAAEAYTPQGYNQCSLDDILKPFQLCADLCQMYWLPPLVLHWARKVPEQQRQQHGEYYRQLLLHPELLIAPIKPEDRDGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1N3</accession>
    <name>D0Z1N3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">50S ribosomal protein L29</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpmC</name>
        <name evidence="6" type="ORF">VDA_003447</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uL29 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302800.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003447"/>
    <dbReference type="EnsemblBacteria" id="EEZ42414">
        <property type="protein sequence ID" value="EEZ42414"/>
        <property type="gene ID" value="VDA_003447"/>
    </dbReference>
    <dbReference type="GeneID" id="57340096"/>
    <dbReference type="eggNOG" id="COG0255">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2063644at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00374">
        <property type="entry name" value="Ribosomal_L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001854">
        <property type="entry name" value="Ribosomal_L29/L35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036049">
        <property type="entry name" value="Ribosomal_L29/L35_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018254">
        <property type="entry name" value="Ribosomal_L29_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00831">
        <property type="entry name" value="Ribosomal_L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46561">
        <property type="entry name" value="SSF46561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00012">
        <property type="entry name" value="L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00579">
        <property type="entry name" value="RIBOSOMAL_L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ42414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="63" mass="7175" checksum="4BF236D1BC3BC82E" modified="2010-01-19" version="1">MNAQDLRAKSVEELNAELVNLLREQFNLRMQAATGQLQQTHNLKNVRRDIARVKTVLTEKASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1Q5</accession>
    <name>D0Z1Q5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Periplasmic protein involved in polysaccharide export</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_003469</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303537.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003469"/>
    <dbReference type="EnsemblBacteria" id="EEZ42436">
        <property type="protein sequence ID" value="EEZ42436"/>
        <property type="gene ID" value="VDA_003469"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="687725at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015159">
        <property type="term" value="F:polysaccharide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003715">
        <property type="entry name" value="Poly_export"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019554">
        <property type="entry name" value="Soluble_ligand-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02563">
        <property type="entry name" value="Poly_export"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10531">
        <property type="entry name" value="SLBB"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="SLBB" evidence="2">
        <location>
            <begin position="95"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="SLBB" evidence="2">
        <location>
            <begin position="203"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="SLBB" evidence="2">
        <location>
            <begin position="291"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="SLBB" evidence="2">
        <location>
            <begin position="388"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="domain" description="SLBB" evidence="2">
        <location>
            <begin position="582"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="domain" description="SLBB" evidence="2">
        <location>
            <begin position="781"/>
            <end position="822"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ42436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="892" mass="98280" checksum="F6B2BDD5B4AC5817" modified="2010-01-19" version="1">MKIVIALFLFALSFTCWGEILTPGDRIFLQIPGESDFEQPFTINDQGLLLLPEIGPIKVAGLKEPEAEELIFQALSELYRNLDAFKLSVIEQLIRVQVLGYVEKPSAISLQPNSNVQMALTKVGGARPGAQLDQFQLQRQGKTKLFNYKNYLDSGDPSLLPILQDGDILFIPASPLLGNIEVNFDAASLINSGDAGEKHEALTIFGELRNPGLFSYKKGMTVIDALMRADGVTRFADVSKIRVITDNKPYIFDLKYYLDTSDASNLPPIKPGTTIFAPIEVEDIGTSKRSIYVMGEVKEAGVFEATSETSFIDALANAGGPTRFADTTHIKLLRTTKPPITINLVAYTKNPQSINLPPLESGDAIFVPEKLDLNEKSWLKVTDDRAIKIIGAVKKPGRYEWSQDMDFMDLLAHAGGPNQQANLSSIRIIKESKNTGHQVLFFDFDGFIKRGSPASLLPNLVAGDSVIIDELPHDPSDNKSSWVRQSAKDSIYIFGSVGAPGRYAFNREQGFLDILSAADGPVAQADLKEVLITHRNGQQRKITRLDLAKYFETGNEKLLPKVLPGDVIYVPPVSSDADDKAVKVMGAVESPGRFKWNSKMTFLDLLAVAGGPTQKANISKIRIIKERSSRTGGNILYFDLERFMDEGGNFNELPKLQAGDSIIIDELPHGPTDNKSTWLRQSAQDSIYIFGAIGAPGRYAFNQQMGFLDILSAADGPTNDADLQNVRISHRNGNHSTVTQLNLTQYFETGDETIIPKVVPGDVIYIPPQDRLWLDKSPQKMVRLMGSVHKPGRYDFNQQMSLLDLLAEAGGPTDKAYIERIMIVNSSCCGDKTQAFNLRDYINDPQKYPLPLLRPGDTVYVPDEGESTSQQIRQAFQDALGIFSLIALGAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1W8</accession>
    <name>D0Z1W8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">50S ribosomal protein L13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">rplM</name>
        <name evidence="7" type="ORF">VDA_003532</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 6">This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the universal ribosomal protein uL13 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303716.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003532"/>
    <dbReference type="EnsemblBacteria" id="EEZ42499">
        <property type="protein sequence ID" value="EEZ42499"/>
        <property type="gene ID" value="VDA_003532"/>
    </dbReference>
    <dbReference type="GeneID" id="57339991"/>
    <dbReference type="eggNOG" id="COG0102">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1822215at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00392">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01366">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005822">
        <property type="entry name" value="Ribosomal_L13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005823">
        <property type="entry name" value="Ribosomal_L13_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023563">
        <property type="entry name" value="Ribosomal_L13_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036899">
        <property type="entry name" value="Ribosomal_L13_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545">
        <property type="entry name" value="PTHR11545"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00572">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002181">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52161">
        <property type="entry name" value="SSF52161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01066">
        <property type="entry name" value="rplM_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00783">
        <property type="entry name" value="RIBOSOMAL_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ42499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="142" mass="15853" checksum="17AF7B59DB8F09E1" modified="2010-01-19" version="1">MKTFVAKPETVKRDWYVVDAEGKTLGRLATEIASRLRGKHKPEYTPHVDTGDYIVVINAEKVAVTGAKKTDKMYHHHTGYIGGLKSISFEKLIAKKPEMVIEIAVKGMLPKGPLGRAMYRKLKVYAGTEHNHAAQQPKVLDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z226</accession>
    <name>D0Z226_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Chromosome partition protein MukF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">VDA_001875</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298855.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001875"/>
    <dbReference type="EnsemblBacteria" id="EEZ40843">
        <property type="protein sequence ID" value="EEZ40843"/>
        <property type="gene ID" value="VDA_001875"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3006">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="231724at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030261">
        <property type="term" value="P:chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16337">
        <property type="entry name" value="MukF_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.225.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.590">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005582">
        <property type="entry name" value="Chromosome_partition_MukF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033441">
        <property type="entry name" value="MukF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038198">
        <property type="entry name" value="MukF_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033440">
        <property type="entry name" value="MukF_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036141">
        <property type="entry name" value="MukF_M_sp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033439">
        <property type="entry name" value="MukF_WHTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03882">
        <property type="entry name" value="KicB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17193">
        <property type="entry name" value="MukF_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17192">
        <property type="entry name" value="MukF_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018282">
        <property type="entry name" value="MukF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140570">
        <property type="entry name" value="SSF140570"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0226">DNA condensation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="KicB" evidence="8">
        <location>
            <begin position="3"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="MukF_M" evidence="9">
        <location>
            <begin position="121"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="MukF_C" evidence="10">
        <location>
            <begin position="283"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="201"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF17192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF17193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ40843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="440" mass="50425" checksum="512F0649FAE8146C" modified="2010-01-19" version="1">MSEVTQTVPELVHWVKQNEFAINLPTERLAFLLAIAVLSGDRFDEELGEGELIDAFRIVSDLFGQTKETLAFRANNAINELVRQRLISRFTSEITDGASIYRLSPLALGITDYYVRQREYSTLKLSIQLAMVADEINKAAKSAQEDGDIKHWRQNVYAVLKFSVAEIFDRIDLNQRTMDEHQQQVKLDIAELLNKDWRAAISSCETLLDETSETLRELQDTLQAAGDQLQTQLLIIQESTQGREELDFVDGMIFILQMKLDRIISWGQQAIDLWIGYDRHVHKFIRTAIDMDKNRAFSQRLRQSVTDYFDNPWLLTYADADRLVDMRDEALILRDDEVTGIVPGELEFEELDLVNDELADRVAEMLSAHKATGAPINLSALLKDYLTQHPLAYHFDLARIVIDQAVRMGYSEDDFNAIQPDWEAINDYGAKVQANVINKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2M7</accession>
    <name>D0Z2M7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">1,4-alpha-glucan branching enzyme GlgB</fullName>
            <ecNumber evidence="10">2.4.1.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Alpha-(1-&gt;4)-glucan branching enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Glycogen branching enzyme</fullName>
            <shortName evidence="10">BE</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">glgB</name>
        <name evidence="13" type="ORF">VDA_000678</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 10">Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Transfers a segment of a (1-&gt;4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain.</text>
            <dbReference type="EC" id="2.4.1.18"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Glycan biosynthesis; glycogen biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.18" evidence="10"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305037.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000678"/>
    <dbReference type="EnsemblBacteria" id="EEZ39658">
        <property type="protein sequence ID" value="EEZ39658"/>
        <property type="gene ID" value="VDA_000678"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0296">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="227746at2"/>
    <dbReference type="UniPathway" id="UPA00164"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003844">
        <property type="term" value="F:1,4-alpha-glucan branching enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102752">
        <property type="term" value="F:1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043169">
        <property type="term" value="F:cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005978">
        <property type="term" value="P:glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02855">
        <property type="entry name" value="E_set_GBE_prok_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00685">
        <property type="entry name" value="GlgB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006048">
        <property type="entry name" value="A-amylase/branching_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037439">
        <property type="entry name" value="Branching_enzy"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006407">
        <property type="entry name" value="GlgB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044143">
        <property type="entry name" value="GlgB_N_E_set_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004193">
        <property type="entry name" value="Glyco_hydro_13_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43651">
        <property type="entry name" value="PTHR43651"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02806">
        <property type="entry name" value="Alpha-amylase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02922">
        <property type="entry name" value="CBM_48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000463">
        <property type="entry name" value="GlgB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01515">
        <property type="entry name" value="branching_enzym"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8 10" id="KW-0320">Glycogen biosynthesis</keyword>
    <keyword evidence="5 10" id="KW-0321">Glycogen metabolism</keyword>
    <keyword evidence="6 10 13" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aamy" evidence="12">
        <location>
            <begin position="237"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="10 11">
        <location>
            <position position="394"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10 11">
        <location>
            <position position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000463-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ39658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="715" mass="82067" checksum="5DE306CBAE6C2E02" modified="2010-01-19" version="1">MQLARAAFSDPFSFLGPQYHNLGIALRVWMPGADAVSVKTQAGDIYPLSRDKESGFVLEGDLDLTSSLYQLIISWPQGEQTINDPYQFHQLISHPQALISPEQMHSEMGAQLLSLNIGNQPVAGVRFLVFAPNASAASIVGNFNGWDGRRHPMQRLDDGLWGLFIPGLEEGVQYKYELKDAQGNGLPHKADPWGYASEQYPSFTSQVYDQHRYQWQDKTWQTRAVTEKHKEALSFYELHAGSWRKNAAGDFLSYRELATELVPYLVEMGYTHVELMPISEHPFYGSWGYQPIGLFSPTSRYGSPDDFKYFVDQCHQAGIGVVLDWVPAHFPSDEHGLANFDGTALYNDPDPRRGWHQDWHSYIYDYGRDHVRRFLVSNALFWFEHYHIDGLRVDAVASMLYLDYSREHDQWIPNCDGGNENYDAISLLRWVNEEVYRHYPNAMTIAEESTAFPGVSRPTSMGGLGFGFKWNMGWMHDSLSYIKEEPVHRQYHHNTITFPLIYAFSENYVLSLSHDEVVYGKGSLLNKMPGDEWQKTANLRAYLGYMYGQPGKKLNFMGTEIAQSAEWAHEGQLEWHWLQYPRHEGVQALVRDLNHLYQDLPQLHQLDCDPAGFEWRMQDDAERSILAHERFDEQGNKVLVVTNFTPVPRENYRLGVPQAGEYELVLNTDSPQYWGSDYAISNLLPTEAIRTQGLEQSINLTLPPLATVFYRFNKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2R4</accession>
    <name>D0Z2R4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ABC type periplasmic iron siderophore/cobalamin binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000715</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305139.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000715"/>
    <dbReference type="EnsemblBacteria" id="EEZ39695">
        <property type="protein sequence ID" value="EEZ39695"/>
        <property type="gene ID" value="VDA_000715"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0614">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1473468at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002491">
        <property type="entry name" value="ABC_transptr_periplasmic_BD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01497">
        <property type="entry name" value="Peripla_BP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50983">
        <property type="entry name" value="FE_B12_PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018855" evidence="1">
        <location>
            <begin position="22"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="domain" description="Fe/B12 periplasmic-binding" evidence="2">
        <location>
            <begin position="43"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="385" mass="42918" checksum="1DF339455FA9E664" modified="2010-01-19" version="1">MKCSTTALALTTLISSFSALATQYPVTITDVSGRQVTIDHKPEHIALSTGRVFPLLEIMYQKDAAKHLVAWRDDMKMSAPSMYKSYLKDFPSLSSLPVIGKIKSGEFDAERFINLKPKPDLFVVDLSNIKLAQDKGLLKKLQQAGIAVLAIDFREDPLRNTVQSVSDLAIALNKEKQGEAFTQYYQKHLNNIKHALADLPKSEDQKNVFIERAAGYDNSCCQTFAAGNMGAYIPFLKAKNIATKPLHGAVTGKMSPETVIASQPDVYIMQTTGWLDKKGKPTGGIPLGYSPVNHQAIAQATKTLMDRNWMPAVKAYQTNNVYSIYMPFYNSPYNLVALEYFAKWIHPTQFTNLDPNKTFIEMNQKFANRKVSGVFGQNNIEAMSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z318</accession>
    <name>D0Z318_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">N-acetylglucosamine-6-phosphate deacetylase</fullName>
            <ecNumber evidence="8">3.5.1.25</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_000819</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="6">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the metallo-dependent hydrolases superfamily. NagA family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.25" evidence="8"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305432.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000819"/>
    <dbReference type="EnsemblBacteria" id="EEZ39799">
        <property type="protein sequence ID" value="EEZ39799"/>
        <property type="gene ID" value="VDA_000819"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1820">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1026967at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047419">
        <property type="term" value="F:N-acetylgalactosamine-6-phosphate deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008448">
        <property type="term" value="F:N-acetylglucosamine-6-phosphate deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006044">
        <property type="term" value="P:N-acetylglucosamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003764">
        <property type="entry name" value="GlcNAc_6-P_deAcase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11113:SF14">
        <property type="entry name" value="PTHR11113:SF14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038994">
        <property type="entry name" value="NagA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00221">
        <property type="entry name" value="nagA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="7">
        <location>
            <begin position="54"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="217"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="303"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="4">
        <location>
            <position position="270"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="214"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="225"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="248"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR038994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR038994-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR038994-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR038994-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ39799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="377" mass="41360" checksum="860F29D5BA1CE2DC" modified="2010-01-19" version="1">MYAITNVNVFDGVEIHHNQIIIIENDTITKVISNDKIMDMQLPNVQIDGKGYLATAGFIDLQLNGCGGVLLNTDPSLNTLDIMNKTNLKTGTTQFLPTFITSDQQAMENIVSIVGELDQPETHGVLGLHLEGPFISIEKKGAHRQEFIRELDLPTARFFAQNADKIRVLTVAPENTSQEAIDIVRNAGITVSLGHTNATYAQVCEKNGLEMATHLYNAMTPLGSREPGVVGYIFDKKPHAGIIVDGIHADYPSVRIAHQLMGEKLFMVTDAVTPAGTDMTEYDMAGVKAYVTNGKCHYEDGTIAGAAITMIEGVRNLIQHVGLSREEALRMASLYPAKAIKIDDSYGKITEGYKANIVLLNDNNQVEHIFQMGRQEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z324</accession>
    <name>D0Z324_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted N-ribosylNicotinamide CRP-like regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000825</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305453.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000825"/>
    <dbReference type="EnsemblBacteria" id="EEZ39805">
        <property type="protein sequence ID" value="EEZ39805"/>
        <property type="gene ID" value="VDA_000825"/>
    </dbReference>
    <dbReference type="GeneID" id="57342735"/>
    <dbReference type="eggNOG" id="COG0664">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1596937at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="1">
        <location>
            <begin position="26"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="224" mass="25989" checksum="5AD2B0A0C98499EF" modified="2010-01-19" version="1">MQLQTLGKGRFEDEWSQDKQLIEQTIRNCISTRRIFDENEKILTQGELVDNLYLVDSGRISMGITARNGKTFLLGTLDCEQQLFGEMEFFTGYRCQMDIVAIEAVEVATIDTIKLQRCLLDHPRLSLYFASAIAIDYQDTVEILSRRLLYPITYNVAYDLYHQYLNDLPIDGFNKDYLEAERFATSDRVYRRAIKELENKGFIIKEKKGICILDHKGLKAFVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z372</accession>
    <name>D0Z372_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000873</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39853">
        <property type="protein sequence ID" value="EEZ39853"/>
        <property type="gene ID" value="VDA_000873"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502Z7J9">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021246">
        <property type="entry name" value="DUF2797"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10977">
        <property type="entry name" value="DUF2797"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="263" mass="29621" checksum="71F637B170C18641" modified="2010-01-19" version="1">MKSTLEQNVNYSLLVGDNEIVLNSLIGKTITLTHTGKIICSSCGKTTKKSYSQGHCFPCMKKLASCDMCIMKPETCHYAQGTCREPSWGEDNCMVPHYVYLSNTSALKVGITRYTQIPTRWIDQGATQGLTILKVKNRHISGLVEIALAKFVADKTNWRNMLKGNNNQLDLKSYSEQLLPEIQKELLAITEQYGDDAIEYLSTESQDIHYPVEQFPTKITSHNFDKSPVVEGILQGIKGQYLIFDTGVINIRKFTSYEVIVSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3C8</accession>
    <name>D0Z3C8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000929</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39909">
        <property type="protein sequence ID" value="EEZ39909"/>
        <property type="gene ID" value="VDA_000929"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="433" mass="51591" checksum="57DE77AE9CCE9EA5" modified="2010-01-19" version="1">MYKRKKINLDHIYESEILKPQYSYKEVYNAIMFYTKNPRIAKYYLRDIYESWSGNLSGEVDFDDLFIIILLKHCEPSAYDYLIKNIRKLNIKDKTEIDNNFKDNTEFFKNMDMASSLIIYILNNNNEFCINRPQSIASCDNGDKKEKYLNLIINNYIPDGYDKEKPFIKKFSYLKDEMSTSNIINNYDKLYAKYSSLFTLKQSDLLARSITCLCSNDIYSIAIFSYLCYINKENGKNSEFILPVEPIIEILKLNRQQIEIDCFAQILRLLFSIAKYYDLYIYKFLSIYLTDLISPKLRDELLYKTQKIIKEEIDKNNLNLKENKHIESIIEISKSLENRELQEIIYNKLIDGELSNKKISFIKFFIKNSKNINEFLDKENRLKELEQSISEYKYDKSDDKISSEISYIKNKLSYVKNGFSYVENNKFYIENET</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3E4</accession>
    <name>D0Z3E4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">TPR domain protein in aerotolerance operon</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_000945</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305797.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000945"/>
    <dbReference type="EnsemblBacteria" id="EEZ39925">
        <property type="protein sequence ID" value="EEZ39925"/>
        <property type="gene ID" value="VDA_000945"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="743737at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001440">
        <property type="entry name" value="TPR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13519">
        <property type="entry name" value="VWA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="303"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="5">
        <location>
            <begin position="87"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="392"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="441"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="607"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="456"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="519"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="616"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="642"/>
            <end position="656"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ39925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="691" mass="78533" checksum="A316A37F81B43029" modified="2010-01-19" version="1">MADFTFIHPMWLIAIVPLLLLLPWLKSKSQSSSLIAPHIAAKLGLSQPQHKTWPLYLLGLAWILAVIALAGPSWEKTKLPAYSLSGARVLVMDMSKSMYATDIAPNRLTQARFKALDMLPGWKEGSTGLITYAGDGYTISPLTDDSSTLANLIPSLSPKIMPIPGSNAASGIRQAIDLLKQAGDTNGDIILITDGMTEKESQESLAELKNTHYRVSILAVGTEQGAPIEMPDGRLLTQNGQTVIAKVNPNTLSAITSKTGGLLQFSQADNQGVNNIVKFTAKPRNQLEQGKQKELEERLNNGFWLLLPLILLALLGFRRGIVLAALMVFMPLDYAHANPWKNQDQQGYDNYQQGQYTDAVKDFSSPAWKGIAQYKAGQFHQAIKTLEPLKDTTSRYNLGNAYAQSGQYEKAINTYEEVLKQEPTNTDAKKNLEVVKKALENQQNQQNKQDQSKKQDKQQSQNQQNQQNQQNQQNQQNQQNQQNQQNQQNQQNQQNQQNDSQKNQQKQDSNKQKENKKQNSQSSEQSQQEKDKQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAEAKTDESKGKKGNNKEKELAVTPSQEGKKPGEATVTQSNPILKKLEQIPDDTSELIRAQMILQARQRAQQQQETENSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3H4</accession>
    <name>D0Z3H4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000975</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305885.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39955">
        <property type="protein sequence ID" value="EEZ39955"/>
        <property type="gene ID" value="VDA_000975"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1573">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1983750at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036895">
        <property type="entry name" value="Uracil-DNA_glycosylase-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52141">
        <property type="entry name" value="SSF52141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="244" mass="27550" checksum="528EE992B49666BA" modified="2010-01-19" version="1">MKGDNSLQKKHQQLIRLAQKRRCLTPNGFNSITDYHHGAYDCDYVSPYSKYAGNLNASVMLILQDWCSDDFLSQPLNRNLIHYGIEPSFPTTRNLEQYLQRYFQLSVAQTYGTNLFPFVKPGAMAGNITIGELIQAAEQFTLEEIEIIAPKVAVCFGVATYNALLRAAKEQNRLKDASLKPVKNLNQAIEQPFLLSFSSKVKVWICAQSHPGGLGRACRNKGKVDRVSQDWQQMAQFVKQIPFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3R6</accession>
    <name>D0Z3R6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001067</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306135.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001067"/>
    <dbReference type="EnsemblBacteria" id="EEZ40047">
        <property type="protein sequence ID" value="EEZ40047"/>
        <property type="gene ID" value="VDA_001067"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0697">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1515911at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="159"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="198"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="229"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="259"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="285"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="10"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="158"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="318" mass="33719" checksum="98653E87D728E9AC" modified="2010-01-19" version="1">MSKTAPNKSLGLTLALICAALWGASFPLGGVLAGKLDPVVLAIARYAIATLCFVAVFIFSKKHTLKKIQSKKDAILLMAAGISAQAVFFYFTILAYEYTSSGEIGVINGMAPFLTMAAVFVIDKIKPSAPKVFAVVLSLVGAAVIAYDPSNKIQGLNLGHLFALCGVLGFVTYNYILGKFGSDLNSRYDLYSSSFYQFASATVALFILAIVTGADFSSAAVLVENGKNLGSILALGLLCSGFAYALWELATLKTQDAVITTMALNVLPLFAMIVAYFLLGEVMTLQKLAGVVTVVIALCIYTVGDKFKKKPTVHQATV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-12-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3S2</accession>
    <name>D0Z3S2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001073</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306151.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001073"/>
    <dbReference type="EnsemblBacteria" id="EEZ40053">
        <property type="protein sequence ID" value="EEZ40053"/>
        <property type="gene ID" value="VDA_001073"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4225">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="982403at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010905">
        <property type="entry name" value="Glyco_hydro_88"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07470">
        <property type="entry name" value="Glyco_hydro_88"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="347" mass="39440" checksum="6A27DA5896FD73C1" modified="2010-01-19" version="1">MEAKANILTVMKQVYQYQAQNQTRSVVRRSGKTRFIKDTDWERGVFWSCVAAAWQATDDNDYLDGVMNYTLHTGFRPGPNGRFADDHICCQAYLDVYPLINKEEALEPTIKALDLMVNEPQPGRQDWWWCDSLFMAPPSFAALSQATGDSKYLTYMNTAFWDAVEHLKDPETGLFYRDHRYIPDGNGSELREANGEKVFWSRGIGWVLAAVPRLMARMPEDFADKPRYLTLFTELAAEVIKYQQEDGFWRTSLLDPQNYPAKESSATALFCYGLAWGVRTGLLDEATYLPVVEKAWAALGECIHDNGMIGWVQLPAFNPRDVQFEHNIDYGAGAFLLAGTEVLHLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3T7</accession>
    <name>D0Z3T7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001088</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306192.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40068">
        <property type="protein sequence ID" value="EEZ40068"/>
        <property type="gene ID" value="VDA_001088"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2944">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1933795at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="321" mass="37556" checksum="1C87E52662FD3C7E" modified="2010-01-19" version="1">MSNCFAQIFTKHRKAQGLTQKEMLDFLYQQNEVFSSLDAVTLSRWERGKTVPPMEKRLFVLSLINKVEEYFCLEAVQGEYESGLVNKILNKRYSKVISLAAMFKTEQVQQDYQLNFSTFNDTPKEVLGYFSNRNRFAGQICDQINAQLGYWEDNNQIFGFFIHAPIKTEMLSILSGHIDDMMNQVKFESSPPSQCDALFLFDQINLTQECFELSNLRLFLLLLANPQYKQLYICIHDQMYLNLMLRLGAEVVCTYQTEEMKETGIEHSQLVVFDSLKFISNKSVFEFFANVYNKLNRNNPDLLKQLRESNETRSNRFKAYC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3Y0</accession>
    <name>D0Z3Y0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator AraC/XylS family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001133</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306303.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40111">
        <property type="protein sequence ID" value="EEZ40111"/>
        <property type="gene ID" value="VDA_001133"/>
    </dbReference>
    <dbReference type="GeneID" id="57343399"/>
    <dbReference type="eggNOG" id="COG2207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1757088at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003313">
        <property type="entry name" value="AraC-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020449">
        <property type="entry name" value="Tscrpt_reg_HTH_AraC-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02311">
        <property type="entry name" value="AraC_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00032">
        <property type="entry name" value="HTHARAC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="1">
        <location>
            <begin position="160"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="264" mass="30608" checksum="0A8562CA8F0A8CBF" modified="2010-01-19" version="1">MKNVYRPIFDDNNPPAEIFFGHEVFLPNTGTIPHWHSWGQLQLISGGIMELKTQNKRFLSPPQYAVWVPPTVTHESYIRRSLDYCSMNIIAPLASTLPSYPCLLEISPIIEAIVNDFRRRKLIYPQTPEDERLVKVLLDQVLQCPIHQQFLPTSDDKLLNPILVELEKNPTNAKSLAQWASELHTTERTLARHCQDKLGMSFTEWRQRRKYIYSLHLLRKGMTVKEVALTLGYHQASPFITLFKKHSGSTPEQYRQRIGMDIQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3Z4</accession>
    <name>D0Z3Z4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">CBS domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">VDA_001147</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001147"/>
    <dbReference type="EnsemblBacteria" id="EEZ40125">
        <property type="protein sequence ID" value="EEZ40125"/>
        <property type="gene ID" value="VDA_001147"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1253">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04590">
        <property type="entry name" value="CBS_pair_CorC_HlyC_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002550">
        <property type="entry name" value="CNNM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044751">
        <property type="entry name" value="Ion_transp-like_CBS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005170">
        <property type="entry name" value="Transptr-assoc_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03471">
        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01595">
        <property type="entry name" value="DUF21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01091">
        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51846">
        <property type="entry name" value="CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0129">CBS domain</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="CNNM transmembrane" evidence="10">
        <location>
            <begin position="1"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="9">
        <location>
            <begin position="278"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ40125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="441" mass="48717" checksum="7810E4BB3835882B" modified="2010-01-19" version="1">MEIAILIGLILLNGVFAMAEIALVTAKRSRLQRLAEDGKSGAQTAINLGTNPTRFLSTIQIGITAIGLLNGIYGESALAGPMAQWLIELGMHAKTASIASTAIVVLGITYLSIVLGELVPKRLGQYYPEAIAQVIAKPISFLASVSKPFVWLLSLSTEGFLALMGKRGGDGQQLTEEDIEAVIAEGSESGVLEKQEHDMVKNVLHFDRRKISSLLTPRNDLVYIDLEQGQESNLQKILAAKFTSFPVCKGGIENIQGFITAKQYLQFISHPDHEITDFISAPVFVPENWTGPKLLELFKQSGNSMVFVVDEYGDLQGIVTPKDILEALAGEFNIRNPEDVWSVQNADNSWTMDGLLPIAVLKELLELKSLPDEEENGYHTLSGMIMWQRGELPKPGDCIYWQGWRFEVVAIQSNRVDRVFVRHQTTSDTKQEQFIQTSLDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z401</accession>
    <name>D0Z401_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cytochrome-c peroxidase</fullName>
            <ecNumber evidence="6">1.11.1.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_001154</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.11.1.5" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001154"/>
    <dbReference type="EnsemblBacteria" id="EEZ40132">
        <property type="protein sequence ID" value="EEZ40132"/>
        <property type="gene ID" value="VDA_001154"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1858">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004130">
        <property type="term" value="F:cytochrome-c peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004852">
        <property type="entry name" value="Di-haem_cyt_c_peroxidsae"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025992">
        <property type="entry name" value="Haem-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03150">
        <property type="entry name" value="CCP_MauG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00034">
        <property type="entry name" value="Cytochrom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14376">
        <property type="entry name" value="Haem_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01235">
        <property type="entry name" value="Haem_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome c" evidence="5">
        <location>
            <begin position="104"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="5">
        <location>
            <begin position="256"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="385" mass="42849" checksum="4F137FF03AFAC8E7" modified="2010-01-19" version="1">MERDVRNAQRQFNISGMLENMQQGKPISDVDLAKLESVLEDGSMPPKLYLTMHWRSDLSDDEKNTLLDWVRQQRAEQHANTGVTAEFKYAAVQPITTTFKVNQAKVKLGDELYHDTRLSSDNSVSCATCHDLNRGGVDRLNTSTGVGGAKGPINAPTVFNAVFNIHQFWDGRAFDLQAQAGGPPLNPKEMASTSWNQIITKLDKDPVLKAQFDALYKQGITEETITDAIAEFEKTLVTPNSRFDKYMRGDKSALNAEEIAGYKLFNKYKCQTCHAGEAMGGQTFEILGVKKDYFADRGTPLTDADKGRIGVTNDPNDLHRFKVPTLRNVAQTAPYFHDANAKTLDDAVNKMALYQVGVTLQPQETKEIVAYLKTLTGEYNGKLVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z412</accession>
    <name>D0Z412_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001165</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40143">
        <property type="protein sequence ID" value="EEZ40143"/>
        <property type="gene ID" value="VDA_001165"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="37" mass="4085" checksum="6BE9714B647375C8" modified="2010-01-19" version="1">MIAGVASDNQASAHLLVKLGFVFQVKEQDVMFFKLVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z444</accession>
    <name>D0Z444_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Integral membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303982.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000300"/>
    <dbReference type="EnsemblBacteria" id="EEZ39282">
        <property type="protein sequence ID" value="EEZ39282"/>
        <property type="gene ID" value="VDA_000300"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0697">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1515911at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="163"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="191"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="221"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="251"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="276"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="6"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="160"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="310" mass="32658" checksum="D3AE8C9892DD436A" modified="2010-01-19" version="1">MNPKTLGYSTMIISATLMGCVGLFARNINTSGDVIAFTRMVVGAVCIFALMYYQGKTLQIKSTKLSPTVIASGACLGLCLAAYVSATQYTTLANAVFLIYTGPVVSTILAAIFLKEKISALTAGFLSAVFVGCLLIIGVIGYTPESGFTMSLSFSKETMLGDMLGLTSGIGYGLYLFFSRYRTDVSSDSRSFFNFLFGAIAIGVCFMINPPSLAEMNASSWVWLLAMGFFIGFGALSLLTIAAKHLKAAELACVSYLETVVGAGIGIMMFNESLTTLQAIGGILVIGGGMGEIVISIAKKRQTTKSAPAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z460</accession>
    <name>D0Z460_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MSHA pilin protein MshA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000316</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000316"/>
    <dbReference type="EnsemblBacteria" id="EEZ39298">
        <property type="protein sequence ID" value="EEZ39298"/>
        <property type="gene ID" value="VDA_000316"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2165">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="185" mass="19979" checksum="7CD1F4B3FCAC46E3" modified="2010-01-19" version="1">MVGFTLIELVVVIVILGILAVTAAPKFLGLQVDARNAALKGLEGSLKSALGVGYAKMVILGAENSAYATNRTTDGGSGMFSLDMSSIGCPVDDDDIFCVFKYGYASELNTFKQLVQNISQPTENKSDWVTFYGKGGIIFTNKNNATTTGTGQNQKSSLKQEQCYLLYNPPQEAGEMYSMTYYPCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z480</accession>
    <name>D0Z480_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SIR2_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000336</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304082.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39318">
        <property type="protein sequence ID" value="EEZ39318"/>
        <property type="gene ID" value="VDA_000336"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502Z7ZR">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="503036at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039444">
        <property type="entry name" value="SIR2-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13289">
        <property type="entry name" value="SIR2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SIR2_2" evidence="1">
        <location>
            <begin position="117"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="379" mass="44469" checksum="0442F007F97AA793" modified="2010-01-19" version="1">MTTSKIDLNDLHDKNINYLIGAGASAGLFPTLALNMHTEGKWETIETLATEFDYIDAKHLKALLFMYYYEECIKPVSSVDFTALEDDEQTVIDNYKKFMKLNLEILRRKRGYDRKINFFTTNYDSCLAYAADELYEEKSIRFNINDGSRGFHKKIVEARNFDCMTTESGIFDRNKEVQRQINIIHLHGSAFWRKHNDSILVDYSSAGQIVSESSIDSMYYDDFKEMLESGSHTVDQLCSMIIDDDNEAAFERIQDNFYREYNQLPIVNPTKWKFHETVFEEHYYQMLRHLSYELEKPNSVLIAFGFSFADEHIRNLIKRSLTNPTLQVYICCYRETMIPELQKYFSDFNNIKYVVHEEGEALDFSYFNSHVLTLGEDDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4K3</accession>
    <name>D0Z4K3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cardiolipin synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000461</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000461"/>
    <dbReference type="EnsemblBacteria" id="EEZ39441">
        <property type="protein sequence ID" value="EEZ39441"/>
        <property type="gene ID" value="VDA_000461"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1502">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019637">
        <property type="term" value="P:organophosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025202">
        <property type="entry name" value="PLD-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13091">
        <property type="entry name" value="PLDc_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00155">
        <property type="entry name" value="PLDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PLD phosphodiesterase" evidence="1">
        <location>
            <begin position="190"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="1">
        <location>
            <begin position="425"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="534" mass="60106" checksum="CDC19545C3D55EB9" modified="2010-01-19" version="1">MSNSLQCRHLFDCFCYPMTLISFFKRHGLVRASQMLAAGVVATLTGCAQTLPQNDKATSYSYVDNHDTALYQYAKPYTQAHPGKTGFYPLADGRSAFLARLATIEGAQKSLDVQYYIYRDDETSKLMTWYLHQAAERGVRVRLLLDDMQSRDDDALASLSAHPNVEVRLFNPFANRSIKQVGFLHDFGRLNRRMHNKAIIADGTFAITGGRNIGDEYFSANNSVEFGDFDLLLVGKVVPEVAKQFDTYWNSTPAIPIESLVDDIHLPTQDQINQWRTAQMKYLQESEYAQSLKSHPMVQKLMANSLPFYWADATLNYDSPYKVLDKTNDLLMHDLALAIKEAKTDFVLVSPYFVPTKQGAELLANSAKKGLNVTVVTNSLASNDVFAVHGWYAKYRDIMLKGGVKLYETKVDPKHKAKRSLVGSSRTSLHAKSFVIDNRKVFVGSFNFDPRSAYLNTEMGIFVDSPEFAEVVNKDLNKLLTKTAYRLTLDDDDDGDIVWHDDETGETFTSEPDSSVWLKMGAWFAGALPIESQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4P6</accession>
    <name>D0Z4P6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000504</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304559.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000504"/>
    <dbReference type="EnsemblBacteria" id="EEZ39484">
        <property type="protein sequence ID" value="EEZ39484"/>
        <property type="gene ID" value="VDA_000504"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="190" mass="21870" checksum="358CCCB79026708C" modified="2010-01-19" version="1">MKFEFLNTEIVALVNFVAAMFTIAAAVIALITLLSWKKQQLLGPKLNAVLEAEDCYCLVVQGYMQNFSFFFHCSKLAFETRNAPKETRAEANNVISRESEKLNFEKQALHDSNFQLAVLRMQRLGLIAEIDKSMDTKHLTEIFEGYLERIQKHDYSDEDSNNDLLSSFAHEIYWIQDSGKQAFKTIRDSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z503</accession>
    <name>D0Z503_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ISPsy3 transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000236</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000236"/>
    <dbReference type="EnsemblBacteria" id="EEZ39220">
        <property type="protein sequence ID" value="EEZ39220"/>
        <property type="gene ID" value="VDA_000236"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0582">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007069">
        <property type="entry name" value="Transposase_32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026889">
        <property type="entry name" value="Zn_Tnp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04986">
        <property type="entry name" value="Y2_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14319">
        <property type="entry name" value="Zn_Tnp_IS91"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn_Tnp_IS91" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="356" mass="42090" checksum="27829A783B38A3DF" modified="2010-01-19" version="1">MGSKHYECENPSCEHRKVIYNSCKSKACSSCGVMLTEKWIAKQLSILPKCEYQHMTLTMPDKLWPIFRLNPWLINLLYRCAVSAFLSFAKKRGIEIGLFCVVHTFGRQLNWNVHFHLSVTRRGVNLKTKRWGNIYFNAAMVEQHWKQQVVSFLRDHYNALNTKHDNYQHIRDFRGWSQFLSSQYSRKWRIHLAKKAEDVGPTVRYLGRYFKRPPIAASRLRHYQGGDVHFVYKDHRDNCYKTLVLSQIEMIDRLVSHIPAEKNFRAIRYYGFLSNRKRGEALPLVYDLLDQEELVEPKPLNYAQMMHHLVGIDPYKCILCGGRMCFVKMEMGLKGHELVALRKATIREKRRLRYSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-06-02" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z514</accession>
    <name>D0Z514_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_000247</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the transposase 7 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000247"/>
    <dbReference type="EnsemblBacteria" id="EEZ39231">
        <property type="protein sequence ID" value="EEZ39231"/>
        <property type="gene ID" value="VDA_000247"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4644">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002513">
        <property type="entry name" value="Tn3_Tnp_DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01526">
        <property type="entry name" value="DDE_Tnp_Tn3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0814">Transposable element</keyword>
    <keyword evidence="3" id="KW-0815">Transposition</keyword>
    <feature type="domain" description="DDE_Tnp_Tn3" evidence="7">
        <location>
            <begin position="383"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="476"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="476"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ39231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="800" mass="90889" checksum="EE53B3097FE9397E" modified="2010-01-19" version="1">MDRLLESSDNQSSKLTWLLQPPGKINGKNVLQHLDRLSHLESLALPEGIDRAIHQNRLLKLAREGRKMSSRDLTRFSAARRHAVLVCVLEEARATLTDEVIELHERMLNSLFSKAKRTQAERLQQTGKLIQSKLRQYIDVGQALSDARDSGGDPWVAIENRLPWPEFVASLEETRHLARKNNFDPLHIITEKYSTLRKYAPRMLSALQLVATPAAQPLADALIVIKDMYRKQSRKVPTTVPLEFVPESWRKVVITPAGIDRQYYEFCALSELKGALRSGDIWVKGSRRYKNFDDYLIPEKDFAKLTPALPISVDYHEYITSRMTLLQSRLEEVNGVAALGELPDVEISDKGVKVSPLDNCVPAQVSPLAELVYSMLPRPKITEILDEVNSWTTFTQHFSHIKNDITRPDTRLLLTTILADGINLGLTKMAEACPGSTKSSLEDIQAWYIRDETYSAALAELVNAQRKRPLSAFWGDGTTSSSDGQNFRTGSSGRYAGQVNPKYGQEPGRQFYTHISDQYSPFYTCIISRVRDSTHVLDGLLYHESDLEIREHYTDTAGFTDHVFALMHLLGFAFCPRIRDLHDKKLFIKEKADQYPALQSQISTTNLNLKEIEIHWHEVLRLATSIKQGTVTASLMLKKLASYPKQNGLAKALREIGRIERTLFMLDWFRDPALRRRVQAGLNKGEARNALARAVFLHRLGEIRDRKPENQSYRASGLTLLTAAISLWNTVYMERAIDALKRKGVKINEQLLSHLSPLGWEHINLTGDYIWKSNRIPASGKFRRLRPAKVARSKNNLNVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5K1</accession>
    <name>D0Z5K1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NYN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000019</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000008">
        <property type="protein sequence ID" value="EEZ38993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005307277.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000008.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ38993">
        <property type="protein sequence ID" value="EEZ38993"/>
        <property type="gene ID" value="VDA_000019"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1432">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="990092at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021139">
        <property type="entry name" value="NYN_MARF1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01936">
        <property type="entry name" value="NYN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NYN" evidence="1">
        <location>
            <begin position="9"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ38993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="222" mass="24975" checksum="8D0529B6FC52C944" modified="2010-01-19" version="1">MPINELPTIALFVDADNTSPSNFTFVIEQLLKRGQIHYRHIYGNWTKPCLSSWHEVGQLHAAQFIQVFDLCSHKNASDIAMVVDILEWNQSHPNHVIAIMTSDSDFTPLLNQLRRHQITTIGIGNANCSIHLQKSFSTFIPIPVKETISPTKPKTITFPDSKSKILVETARSLNANIDAVPIGMIGSQLKGRLTYPAGKLKKLLQEYPQFFSFSGDYVRLKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVM9</accession>
    <name>D0YVM9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative lipase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001610</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298373.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001610"/>
    <dbReference type="EnsemblBacteria" id="EEZ40583">
        <property type="protein sequence ID" value="EEZ40583"/>
        <property type="gene ID" value="VDA_001610"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1123563at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020009">
        <property type="entry name" value="Extracell_lipase_Pla-1/cef_e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025920">
        <property type="entry name" value="Lipase_bact_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12262">
        <property type="entry name" value="Lipase_bact_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03502">
        <property type="entry name" value="lipase_Pla1_cef"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019822" evidence="1">
        <location>
            <begin position="19"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="domain" description="Lipase_bact_N" evidence="2">
        <location>
            <begin position="30"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="798" mass="84473" checksum="89D3864E7DB64B38" modified="2010-01-19" version="1">MKKHYLALIIAASLGLTACGGDSKTTGTPTVNPDIADSLKAETKVNFDIISNPTAPIIVMPTYLAMDQQDGTLSVESSAVDPTNLGDPLVAMGETDGWSTSQPIQISFTGNPLDPTTGSDSFHLIKSGDPTNLADTTQPTELVADVDYKVMISGDTLTAILLKPLDPASNYMFAVTNDLLDSKGNPVGMSNSYAAIKATTPPPSSALLPAQAITHATENEFAQVGVDKSKIIFSSWFTTASVGDVLFAAKSATALAIQNGAESVWKGTAKAEDITPSQLSSLFKIGSPTKAGKTVEGKGEIYKGNITLPYYLDIRPDHFLTTPWQSGMPSLAKIQYVLTHGNDADKQAVQQQLNDLGVDPQDLAVVATDPKAQVRVLSALTGAKITLADGKQLDPQRIITRYSPVPELKSVQTFEYTLVLPTKAECQQPLTNAVTIYQHGVTSSKETLTKSALADQLIGDQCRAIFAINHPLHGDRGVAGQNAATNPSMYLNLASLTVARDNLRQSVTDVINLRASIGKIFAQMAQAPESIASLGVLKRLNPTVGVNFVGHSLGAITGVDVANIANRSIGNEVADQTFFNIDAVALANPGAEIPYLLLNSQGFSPLIKGSIVASVDKQFAAQCGNTNLGICYAVYQNKLINDGTPESLATLQALYASFNQFAFAAQTVMDTVDPINHSAFVPKELPVYLAQVKNDLVIPNYTPLGQTVAGTDIPVPYSPFTGTTPLLKTLALTPTTVSIKDSIVRNAALFNAGVHSSLLDPKPSEAVTAEMQSEVHSFISSNGKELTISDNSVLESQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVR4</accession>
    <name>D0YVR4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_002005</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299155.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002005"/>
    <dbReference type="EnsemblBacteria" id="EEZ40973">
        <property type="protein sequence ID" value="EEZ40973"/>
        <property type="gene ID" value="VDA_002005"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4886">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="883339at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="203"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="403" mass="44881" checksum="D2AF2B02D42A34A5" modified="2010-01-19" version="1">MQTLAQLKAGELRGITHLKISEQLTEFPMEILDLAETLEVLDLSGNQLNAFPAEFAQLTKLKIVFASNNPFTTLPEVLGRCPNLEMIGFKSCAIKEVPANSLPPKLRWLILTDNNIEQLPDTLGQCVHLKKLALAGNQLTSLPQSMLHCHELELVRISANQLTECPDQLLNLPKLAWFAFSGNPFSQHNLELDTVPCVDFSQLELHHVLGQGASGVISKATWTHNEHQLPDEVAVKVFKGEVTSDGYPNDELQACLKAGSHPNLVKSLAQVQQPDNLALIMDLIPSHYQNLGLPPTLVTCTRDTFPADFSLEQTQIDKIVQQMRDVFTHLHQNKVCHGDLYAHNTLFDRDANILVGDFGAASMYHMLSESQQQQIRQIEQRALEHFIDDLASICVQTPDKIVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVW0</accession>
    <name>D0YVW0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002041</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299253.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002041"/>
    <dbReference type="EnsemblBacteria" id="EEZ41009">
        <property type="protein sequence ID" value="EEZ41009"/>
        <property type="gene ID" value="VDA_002041"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5032CKV">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1778696at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="291" mass="33095" checksum="C8999E44EC68A007" modified="2010-01-19" version="1">MARLFQAIRELSGNEANISIPRVYIRFCSGDLNQAAVLSQLVFWSGCASSKNDGWFYKRHEQLAEELCLSVDQIRYTLKKLKTRLGESLGTTRKKAEGVPTIFYRFDEEKLMDLIFPEDNSDSVNLPNGNGEITESIRGSHRNLGFGNLPESIYRLNTDPIKQINNPIVPCEEHQLDILNDQNLEPVEPPTKKTRAKRKPKTTLPEDFCLTEAMQAWYSVQGFSLNIQAATNQWMDAMLARGQCYQDWTAAWRSGMRNANQWATERMVKQSSAVNKMGASNGDYGPPEDYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVY2</accession>
    <name>D0YVY2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 12">Fructose-bisphosphate aldolase</fullName>
            <shortName evidence="12">FBP aldolase</shortName>
            <ecNumber evidence="5 12">4.1.2.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">VDA_001242</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 12">Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:14729"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.1.2.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11 12">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="11 12">Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 12">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 4/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 12">Belongs to the class II fructose-bisphosphate aldolase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.13" evidence="5 12"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297710.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001242"/>
    <dbReference type="EnsemblBacteria" id="EEZ40220">
        <property type="protein sequence ID" value="EEZ40220"/>
        <property type="gene ID" value="VDA_001242"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0191">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="827430at2"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00183"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004332">
        <property type="term" value="F:fructose-bisphosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00946">
        <property type="entry name" value="FBP_aldolase_IIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000771">
        <property type="entry name" value="FBA_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006411">
        <property type="entry name" value="Fruct_bisP_bact"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30559">
        <property type="entry name" value="PTHR30559"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01116">
        <property type="entry name" value="F_bP_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001359">
        <property type="entry name" value="F_bP_aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00167">
        <property type="entry name" value="cbbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01520">
        <property type="entry name" value="FruBisAldo_II_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00602">
        <property type="entry name" value="ALDOLASE_CLASS_II_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00806">
        <property type="entry name" value="ALDOLASE_CLASS_II_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="8 12 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 11 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11 12" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Dihydroxyacetone phosphate binding" evidence="10">
        <location>
            <begin position="265"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Dihydroxyacetone phosphate binding" evidence="10">
        <location>
            <begin position="286"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="9">
        <location>
            <position position="109"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="226"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="227"/>
        </location>
        <ligand>
            <name>dihydroxyacetone phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="264"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001359-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001359-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR001359-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU366023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ40220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="358" mass="38807" checksum="EF4281FB3FD1EB0B" modified="2010-01-19" version="1">MSKIFDFVKPGVISGDDVQKVFEVAKENKFALPAVNVVNTDTINGVLEAAAKVKAPVIVQFSNGGAAFFAGKGLKLEGQEAQIKGAVAGAKYVHAIAETYGVPVILHTDHAAKKLLPWIDGLLDAGEEFFAQTGKPLFSSHMIDLSEESLEDNIAISSKYLERMAKMNMTLEIELGCTGGEEDGVDNSHMDQSELYTSPEDVAYAYEKLNAISPRFTIAASFGNVHGVYKPGNVVLTPTILRDSQAYCSEKFGLPANSLNFVFHGGSGSTEAEIQESIGYGVIKMNIDTDTQWASWDGVRKFEAENHDYLQGQIGNPTGPDAPNKKYYDPRVWLRAGQASMVARLEKAFADLNAIDVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVY9</accession>
    <name>D0YVY9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD</fullName>
            <ecNumber evidence="5">2.1.1.190</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">23S rRNA(m5U1939)-methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rlmD</name>
        <name evidence="9" type="ORF">VDA_001268</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>S-adenosyl-L-methionine + uridine(1939) in 23S rRNA = 5-methyluridine(1939) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42908"/>
            <dbReference type="Rhea" id="RHEA-COMP:10278"/>
            <dbReference type="Rhea" id="RHEA-COMP:10279"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74447"/>
            <dbReference type="EC" id="2.1.1.190"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.190" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297755.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001268"/>
    <dbReference type="EnsemblBacteria" id="EEZ40246">
        <property type="protein sequence ID" value="EEZ40246"/>
        <property type="gene ID" value="VDA_001268"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2265">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1421660at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070041">
        <property type="term" value="F:rRNA (uridine-C5-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01010">
        <property type="entry name" value="23SrRNA_methyltr_RlmD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001566">
        <property type="entry name" value="23S_rRNA_MeTrfase_RlmD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030390">
        <property type="entry name" value="MeTrfase_TrmA_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030391">
        <property type="entry name" value="MeTrfase_TrmA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002792">
        <property type="entry name" value="TRAM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010280">
        <property type="entry name" value="U5_MeTrfase_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11061">
        <property type="entry name" value="PTHR11061"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01938">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05958">
        <property type="entry name" value="tRNA_U5-meth_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51687">
        <property type="entry name" value="SAM_MT_RNA_M5U"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50926">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01230">
        <property type="entry name" value="TRMA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01231">
        <property type="entry name" value="TRMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="4 5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 5 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TRAM" evidence="8">
        <location>
            <begin position="11"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="397"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5 6">
        <location>
            <position position="397"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <position position="273"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <position position="302"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="307"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <position position="323"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="350"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <position position="371"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ40246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="441" mass="49756" checksum="D258E4ECD9FCD44B" modified="2010-01-19" version="1">MARFFKPQKRKITDTKHKEITITRLDHLGAGIGHLNNKPVFVEGVLPGESAVVQFTEDKKQYARARVIKRLTDSQARIKPQCPIYDQCGGCNLQHLSHQGQVTAKQQSLTELMTKFAGADQAITQAKPIVGPDTHYRRCARFGIRLDNRGQLQFGFRKKQSKEIVDVPQCMVLAQSLNELLPVLRELLNSLKGRKHLGHVELVEADNGRVVMIRHLQPFSDADMSKLLEFAKSQQIMLFMAPTADSIEQIFGDRPYYELDCQKLYFSPKDFIQVNRDVNIAMVKQAIDWLDVQADDRVLDLFCGLGNFSLPLAKRANTLVGVEGVDEMVHRAQDNAQYNQINNAAFFQANLEQDVTEFSWAKKPFNKILLDPARAGAAGVMEHVVKLAPEKVVYVSCNPATLARDSQILLHKGYQLTQLGMMDMFPHTGHLESMALFVRSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW71</accession>
    <name>D0YW71_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Bifunctional uridylyltransferase/uridylyl-removing enzyme</fullName>
            <shortName evidence="8">UTase/UR</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Bifunctional [protein-PII] modification enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Bifunctional nitrogen sensor protein</fullName>
        </alternativeName>
        <domain>
            <recommendedName>
                <fullName evidence="8">[Protein-PII] uridylyltransferase</fullName>
                <shortName evidence="8">PII uridylyltransferase</shortName>
                <shortName evidence="8">UTase</shortName>
                <ecNumber evidence="8">2.7.7.59</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="8">[Protein-PII]-UMP uridylyl-removing enzyme</fullName>
                <shortName evidence="8">UR</shortName>
                <ecNumber evidence="8">3.1.4.-</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="8" type="primary">glnD</name>
        <name evidence="11" type="ORF">VDA_001356</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>[protein-PII]-L-tyrosine + UTP = [protein-PII]-uridylyl-L-tyrosine + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:13673"/>
            <dbReference type="Rhea" id="RHEA-COMP:12147"/>
            <dbReference type="Rhea" id="RHEA-COMP:12148"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:90602"/>
            <dbReference type="EC" id="2.7.7.59"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>[protein-PII]-uridylyl-L-tyrosine + H2O = [protein-PII]-L-tyrosine + H(+) + UMP</text>
            <dbReference type="Rhea" id="RHEA:48600"/>
            <dbReference type="Rhea" id="RHEA-COMP:12147"/>
            <dbReference type="Rhea" id="RHEA-COMP:12148"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:90602"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>guanosine 3',5'-bis(diphosphate) + H2O = diphosphate + GDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14253"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:77828"/>
            <dbReference type="EC" id="3.1.7.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="8">Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.</text>
    </comment>
    <comment type="domain">
        <text evidence="8">Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the GlnD family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.59" evidence="8"/>
    <dbReference type="EC" id="3.1.4.-" evidence="8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297911.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001356"/>
    <dbReference type="EnsemblBacteria" id="EEZ40331">
        <property type="protein sequence ID" value="EEZ40331"/>
        <property type="gene ID" value="VDA_001356"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2844">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="162558at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008773">
        <property type="term" value="F:[protein-PII] uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008893">
        <property type="term" value="F:guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006808">
        <property type="term" value="P:regulation of nitrogen utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00277">
        <property type="entry name" value="PII_uridylyl_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013546">
        <property type="entry name" value="PII_UdlTrfase/GS_AdlTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002934">
        <property type="entry name" value="Polymerase_NTP_transf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010043">
        <property type="entry name" value="UTase/UR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47320">
        <property type="entry name" value="PTHR47320"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01842">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08335">
        <property type="entry name" value="GlnD_UR_UTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01909">
        <property type="entry name" value="NTP_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006288">
        <property type="entry name" value="PII_uridyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01693">
        <property type="entry name" value="UTase_glnD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 8" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="2 8 11" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 8 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HD" evidence="10">
        <location>
            <begin position="453"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="domain" description="ACT" evidence="9">
        <location>
            <begin position="694"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="domain" description="ACT" evidence="9">
        <location>
            <begin position="800"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="region of interest" description="Uridylyltransferase" evidence="8">
        <location>
            <begin position="1"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Uridylyl-removing" evidence="8">
        <location>
            <begin position="335"/>
            <end position="693"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ40331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="873" mass="101004" checksum="6F4C6FD907C7D8A2" modified="2010-01-19" version="1">MESLISAVAHYTPSQLNQDSLRQALEQFGEQQKILFKRHHPIADLVHARAKFIDQLLIRLWHHFDFAKHQDLTLVAVGGYGRGELHPLSDIDLLILSHQPLSDELGEQLCQFLTLLWDLKLEIGHSVRTVDQCIDIGREDLTVATNLTESRLLFGNPSAFEQLKQRISLPDFWPSEPYYRAKVDEQIARHARYHDTTYNLEPDIKSSPGGLRDIHTLGWVARRHFGATNLLEMSRFGFLTDAEYRELVECQNALWRIRFALHIELRRYDNRLTFAHQPSVAENLGYKGEGNQAVEMMMKEFYRTLRRVVELNKMLLQLFDQAILNNGLEIDPTPLDDDFQLRGHLIEATKPALFQARPETILDMFLHIAKNSTIDGIAAPTLRQLRTARRRLNRFLVEIPAAREKFMELVRQPNALQKAFRLMHRHGVLAAYLPQWSQIVGQMQFDLFHVYTVDEHSVRLLKNLNKFNDPENRTRHPICCEVFPRIIKKEILILAAIFHDIAKGRGSDHSELGAIEAHDFCLQHGLSRPDAKLVAWLVQKHLLMSVTAQRRDIYDPEVITEFAKEVRDEERLDYLICLTVADICATNQELWNSWKRTLLAELYYATQKSLRRGLENPPDMRERIRHNQQMASALLRSQGFAQRDIDVLWQRFKADYFLRHTHKQLAWHAEALLNHDHEKPLILISKKPTRGGTEVFVYSKDKAKLFAIVVAELDKKNLSVHDAQIMNSKDGYTLDTFMVLDPNGKAISENRHAVISKALKKALTEMKFERKKRRTRRQLLHFNVKTRVDFLATKNGKKTMVELVALDTPGLLATVGSVFANQNLSLQAAKITTIGERAEDFFILINEQGQQLTEEEQILLRNELIDKINQIQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW89</accession>
    <name>D0YW89_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">Lipid-A-disaccharide synthase</fullName>
            <ecNumber evidence="3 11">2.4.1.182</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">lpxB</name>
        <name evidence="12" type="ORF">VDA_001371</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 11">Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>a lipid X + a UDP-2-N,3-O-bis[(3R)-3-hydroxyacyl]-alpha-D-glucosamine = a lipid A disaccharide + H(+) + UDP</text>
            <dbReference type="Rhea" id="RHEA:67828"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:137748"/>
            <dbReference type="ChEBI" id="CHEBI:176338"/>
            <dbReference type="ChEBI" id="CHEBI:176343"/>
            <dbReference type="EC" id="2.4.1.182"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="11">Bacterial outer membrane biogenesis; LPS lipid A biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the LpxB family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.182" evidence="3 11"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297943.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001371"/>
    <dbReference type="EnsemblBacteria" id="EEZ40346">
        <property type="protein sequence ID" value="EEZ40346"/>
        <property type="gene ID" value="VDA_001371"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0763">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1258510at2"/>
    <dbReference type="UniPathway" id="UPA00973"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008915">
        <property type="term" value="F:lipid-A-disaccharide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00392">
        <property type="entry name" value="LpxB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003835">
        <property type="entry name" value="Glyco_trans_19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30372">
        <property type="entry name" value="PTHR30372"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02684">
        <property type="entry name" value="LpxB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00215">
        <property type="entry name" value="lpxB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6 11" id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword evidence="5 11" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="9 11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11 12" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ40346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="380" mass="42733" checksum="53F099831F07FF84" modified="2010-01-19" version="1">MTKPLRIGIVAGEISGDILGAGFIEAVKAQYPDAEFIGVAGPRMQAAGCQALFDMEELAVMGIVEVLGRLPRLFKIKVELVRYFTDNPPDVFVGIDAPDFNLRLERDLKDHGIKTVHYVSPSVWAWRQKRIFKIEKATNLVLAFLPFEKAFYDKFNVPCEFIGHTMADAIPFETDKLAARQLLNLDPNQRYLAVLPGSRGGEMELIAPPFIETCRLLKQQHPDLGFVVALVNQKRREQFEQAWQSIAPELDFVLVDDTARNVMIASDAVLLASGTVALECMLVKRPMVVGYKVKPLTAWLAKRMLKTKYVSLPNILADKELVPELLQEECEPVKLAEQVNRFLAQDNSDLIAEFNQMHQWIRCDADKQAAQAVLKLIDKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWB8</accession>
    <name>D0YWB8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">TsaA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001381</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the tRNA methyltransferase O family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297972.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001381"/>
    <dbReference type="EnsemblBacteria" id="EEZ40356">
        <property type="protein sequence ID" value="EEZ40356"/>
        <property type="gene ID" value="VDA_001381"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1720">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1535774at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09281">
        <property type="entry name" value="UPF0066"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023370">
        <property type="entry name" value="TrmO-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041369">
        <property type="entry name" value="TrmO_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023368">
        <property type="entry name" value="UPF0066_cons_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040372">
        <property type="entry name" value="YaeB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036413">
        <property type="entry name" value="YaeB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036414">
        <property type="entry name" value="YaeB_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12818">
        <property type="entry name" value="PTHR12818"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01980">
        <property type="entry name" value="TrmO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18389">
        <property type="entry name" value="TrmO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118196">
        <property type="entry name" value="SSF118196"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00104">
        <property type="entry name" value="tRNA_TsaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01318">
        <property type="entry name" value="TSAA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51668">
        <property type="entry name" value="TSAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="TsaA-like" evidence="3">
        <location>
            <begin position="5"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00033753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="232" mass="25602" checksum="E81344B18D492E1E" modified="2010-01-19" version="1">MSYQIDPIGIIHSPYKEKFAVPRQPGLVPSARSEIYLQGDANAMEAVRGIEQFSHLWLLFLFDQNLEAGWRPTVRPPRLGGNERVGVFASRATFRPNGIGMSAVELKGVRQQDGQVILELGGVDLVNGTPIIDIKPYIPYSDSIADACGGFASEEPTKLEVIFTPQAQAQLAGPRSAEYQAVISEVLAQDPRPAYKKNKADSKEYAVHLYHFNVKFTVQDSQVIVTTVETDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWF1</accession>
    <name>D0YWF1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Acyl-coenzyme A dehydrogenase</fullName>
            <ecNumber evidence="6">1.3.8.7</ecNumber>
            <ecNumber evidence="7">1.3.8.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">VDA_001399</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a long-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] = a long-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]</text>
            <dbReference type="Rhea" id="RHEA:17721"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="ChEBI" id="CHEBI:83721"/>
            <dbReference type="ChEBI" id="CHEBI:83727"/>
            <dbReference type="EC" id="1.3.8.8"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a medium-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] = a medium-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]</text>
            <dbReference type="Rhea" id="RHEA:14477"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="ChEBI" id="CHEBI:83723"/>
            <dbReference type="ChEBI" id="CHEBI:83726"/>
            <dbReference type="EC" id="1.3.8.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Lipid metabolism; fatty acid beta-oxidation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.3.8.7" evidence="6"/>
    <dbReference type="EC" id="1.3.8.8" evidence="7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297999.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001399"/>
    <dbReference type="EnsemblBacteria" id="EEZ40374">
        <property type="protein sequence ID" value="EEZ40374"/>
        <property type="gene ID" value="VDA_001399"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1960">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="760677at2"/>
    <dbReference type="UniPathway" id="UPA00659"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004466">
        <property type="term" value="F:long-chain-acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033539">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA dehydrogenase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015396">
        <property type="entry name" value="DUF1974"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09317">
        <property type="entry name" value="DUF1974"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0274">FAD</keyword>
    <keyword evidence="9" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="31"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="12">
        <location>
            <begin position="136"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="11">
        <location>
            <begin position="361"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1974" evidence="13">
        <location>
            <begin position="515"/>
            <end position="797"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00020144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF09317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEZ40374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="816" mass="89620" checksum="D309A8706635AB30" modified="2010-01-19" version="1">MVTLAYLLGCILAIAILAYHRVGLKIFTAAITLLLVLGTALSITGVMSWIIFAAIALPLNLPQIRKPYLTAPALRAFQKVMPEMSSTEKEAIDAGTVWWEADLFQGQPDWRKLHDIPAPSLTVEEQAFLDGPVNEVCRMVNDYQVTHELADLPPEVWQYLKDHKFFAMIIKKRYGGLEFSAYAQSLVLQKLTGVSAVLSSTVGVPNSLGPGELLQHYGTEEQKDYYLPRLAQGLEIPCFALTSPEAGSDAGAIPDFGVIKTGLWQGEEVLGMELTWNKRYITLAPIATVLGLAFKLYDPDHLLGDQEELGITCALIPTDLDGVIIGRRHFPLNVPFQNGPTQGNKVFVPLSFIIGGQEMAGQGWRMLVECLSVGRGITLPSNSTGGLKTAALATGAYARIRRQFKMPIGKMEGIEEPLARIVGNAYVMDAASAFTVTGIDLGQKPAVISAIVKYHCTHRSQRGVIDAMDIVGGKGICMGPSNFLARGYQGAPIAITVEGANILTRSMIIFGQGAIRCHPYVLDEMAAAYNPDQKQALDQFDQALFKHIGFVITNMTRSFWLGLTDGRGSSTPYQDPTARYYQQLNRYSANLALLADISMAVLGGSLKRKERLSARLGDVLSQLYLASATLKRFSDEGRQVHDLPLVHWGMQDALYQTEQALLQFLANFPNAIIGSTLKWLMFPLGSCRHQPSDTLDHQLARIAQTPSETRSRLGRGQYLEAQPNNPVGMIEQALQDILAAEPIYDKLCQHVGHKLPFMQLGKIAQWGLDEQVISEQEAQVLRQAEESRLRTINVDDFEPEELAAKPTSKLNMGNAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWK4</accession>
    <name>D0YWK4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sepiapterin reductase</fullName>
            <ecNumber evidence="2">1.1.1.153</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001495</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.153" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298158.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001495"/>
    <dbReference type="EnsemblBacteria" id="EEZ40469">
        <property type="protein sequence ID" value="EEZ40469"/>
        <property type="gene ID" value="VDA_001495"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1261526at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004757">
        <property type="term" value="F:sepiapterin reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="204" mass="22259" checksum="9896F98D78F3DE47" modified="2010-01-19" version="1">MQKILITGGNGDIAKGLVEALSGTFQVEAPLRDELDVSSIASVDKYFSDKTFDIVVNSAGTLYSSTIIDSDPECWIRDINVNLIGTYLVSKAALGKNKKTLIINISSTAAFNAYNDWTSYCASKAGVLKISQGLEKDNYNVITLCPGAIDTKLRDGLNIVNNNVMTLDEGLSPILKAINSEYNNGDIVFYRKNMIEINPNYSQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWR7</accession>
    <name>D0YWR7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hypothetical HlyD family secretion protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001485</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298139.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001485"/>
    <dbReference type="EnsemblBacteria" id="EEZ40459">
        <property type="protein sequence ID" value="EEZ40459"/>
        <property type="gene ID" value="VDA_001485"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0845">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1432684at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018692" evidence="2">
        <location>
            <begin position="28"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="3">
        <location>
            <begin position="51"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="369" mass="39613" checksum="26FD485625B1F36B" modified="2010-01-19" version="1">MKKMAVAVIVSAALAGGYFYFQGTSHAAHKPAPSSRVISVTTGTVGSHSIAQSLSLIGKLQAEQAVTIASEVAAKVKSIEVKPNTRVQKGALLLQLEDDKARAAYNEALAYRNDESRKLNDFKRLISRGAITQTELEAQTASVNIAEARLQAAKAHLSDLSIRAPFNGTVGLYDFSIGHMVPMGGELFSFDDLSSMRLDIQVPEQYLASLQPGMKVSAKSQAWPDRTFSGTVQTIDSRVQADSLNVKVRVTFDNSDNALKPGMLLAADMGFMPHKEALIPVQALEYSGTKRYVYVVDENNIAHRTQVELGARVDNEVVIKSGVDIGEKIVVQGLVNMRDGMKVKDLTAHNSNGAVINPSSKAPSSGVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWV2</accession>
    <name>D0YWV2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Di-/tripeptide transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_001544</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Membrane</location>
            <topology evidence="1 5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40518">
        <property type="protein sequence ID" value="EEZ40518"/>
        <property type="gene ID" value="VDA_001544"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3104">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904680">
        <property type="term" value="F:peptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006857">
        <property type="term" value="P:oligopeptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17346">
        <property type="entry name" value="MFS_DtpA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005279">
        <property type="entry name" value="Dipep/tripep_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000109">
        <property type="entry name" value="POT_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018456">
        <property type="entry name" value="PTR2_symporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11654">
        <property type="entry name" value="PTHR11654"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00854">
        <property type="entry name" value="PTR2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00924">
        <property type="entry name" value="yjdL_sub1_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01023">
        <property type="entry name" value="PTR2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="85"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="147"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="189"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="223"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="255"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="291"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="320"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="367" mass="39357" checksum="FBBFF564BC4637BC" modified="2010-01-19" version="1">MAIGQFTLALPHSMVDPHAVTFFYIGLGFLVVGNGLFKPNISTMVGDLYKEGDHRRDGAFTIFYMGINIGSLLAGVIAGTASTVYGWKAGFLCAGIGMTMSLIIQLLFAERLLGNIGKVPAAHRAAAMNKSGKQEPLTKVERDRLKVILVMCTFVIVFWAGFEQAGGLMNIYSQEYTNRMIGSFEVPAAWFQSLNPFFIIICAPILASIWVKMGKNEPASPVKFALAMFSLALGFACMIGAALEQGGDLTVKTSMMWLVGAYFFHTIGELCLSPIGLSLVTKLAPLRLASLMMGAWFGANAIANYVAGIIGSRLGETGPLAIFSGIAITAIVAGVLLLLLSNKLIDWMHGAEGHKKEEEVEVKTANA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWW3</accession>
    <name>D0YWW3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DNA-binding protein HU-beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001552</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the bacterial histone-like protein family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298263.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001552"/>
    <dbReference type="EnsemblBacteria" id="EEZ40526">
        <property type="protein sequence ID" value="EEZ40526"/>
        <property type="gene ID" value="VDA_001552"/>
    </dbReference>
    <dbReference type="GeneID" id="57342390"/>
    <dbReference type="eggNOG" id="COG0776">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1847472at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000119">
        <property type="entry name" value="Hist_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020816">
        <property type="entry name" value="Histone-like_DNA-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010992">
        <property type="entry name" value="IHF-like_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33175">
        <property type="entry name" value="PTHR33175"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00216">
        <property type="entry name" value="Bac_DNA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01727">
        <property type="entry name" value="DNABINDINGHU"/>
    </dbReference>
    <dbReference type="SMART" id="SM00411">
        <property type="entry name" value="BHL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47729">
        <property type="entry name" value="SSF47729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00045">
        <property type="entry name" value="HISTONE_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="90" mass="9362" checksum="B98F4939A548812F" modified="2010-01-19" version="1">MNKTQLVDKIAENADISKASAGRALDAFIEAVSDTLKSGDQVALVGFGTFSVRERAARTGRNPQTGAEIQIAAAKVPGFKAGKALKDSVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWY0</accession>
    <name>D0YWY0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phage shock protein A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001813</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PspA/IM30 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298753.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001813"/>
    <dbReference type="EnsemblBacteria" id="EEZ40781">
        <property type="protein sequence ID" value="EEZ40781"/>
        <property type="gene ID" value="VDA_001813"/>
    </dbReference>
    <dbReference type="GeneID" id="57342072"/>
    <dbReference type="eggNOG" id="COG1842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="941029at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014319">
        <property type="entry name" value="Phageshock_PspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007157">
        <property type="entry name" value="PspA_IM30"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31088">
        <property type="entry name" value="PTHR31088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04012">
        <property type="entry name" value="PspA_IM30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02977">
        <property type="entry name" value="phageshock_pspA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="47"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="101"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="221" mass="25375" checksum="2C4126E4C9389025" modified="2010-01-19" version="1">MGIFSRFADIVNANVNSLLDKAEDPQKMIRLIIQEMEDTLVEVRTSSARALADKKELQRRINTIEAQTTEWQQKASLALQKGREDLARAALIEKQKLADVALTLNEEYKLVEESIEKLSTEVAELERKLQETRARQQALVVRHKTAGTRRDVRRQLDTGKVDEALAKFEQYERRVDEMEAQADSYSLGRGKSLESEFAELQAQDEIEKELERLKASIKDKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWY8</accession>
    <name>D0YWY8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">Pyruvate kinase</fullName>
            <ecNumber evidence="4 12">2.7.1.40</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">VDA_001821</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + pyruvate = ADP + H(+) + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:18157"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.40"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 12">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 5/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the pyruvate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.40" evidence="4 12"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298770.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001821"/>
    <dbReference type="EnsemblBacteria" id="EEZ40789">
        <property type="protein sequence ID" value="EEZ40789"/>
        <property type="gene ID" value="VDA_001821"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0469">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1098983at2"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00188"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030955">
        <property type="term" value="F:potassium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004743">
        <property type="term" value="F:pyruvate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.33.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1380.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001697">
        <property type="entry name" value="Pyr_Knase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011037">
        <property type="entry name" value="Pyrv_Knase-like_insert_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018209">
        <property type="entry name" value="Pyrv_Knase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015793">
        <property type="entry name" value="Pyrv_Knase_brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015795">
        <property type="entry name" value="Pyrv_Knase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036918">
        <property type="entry name" value="Pyrv_Knase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015806">
        <property type="entry name" value="Pyrv_Knase_insert_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11817">
        <property type="entry name" value="PTHR11817"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00224">
        <property type="entry name" value="PK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02887">
        <property type="entry name" value="PK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01050">
        <property type="entry name" value="PYRUVTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50800">
        <property type="entry name" value="SSF50800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52935">
        <property type="entry name" value="SSF52935"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01064">
        <property type="entry name" value="pyruv_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00110">
        <property type="entry name" value="PYRUVATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 12" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="7 12 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="9 12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11 15" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PK" evidence="13">
        <location>
            <begin position="6"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="PK_C" evidence="14">
        <location>
            <begin position="363"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEZ40789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="481" mass="51449" checksum="54319841177E7505" modified="2010-01-19" version="1">MADKLRRTKIVTTLGPATDRDNNLEKIIAAGANVVRMNFSHGTPEDHIERTKTVRAIAAKLGKHVAILGDLQGPKIRVSTFKDGKIQLAIGDKFTLDSDLPKGEGNQHAVGLDYKELPKDVETGDILLLDDGRVQLQVESVEGNKVNTVVTVAGPLSNNKGINKKGGGLSAAALTEKDKADILTAAKMGVDYLAVSFPRNGEDMKYARRLAEEAGLQAKLVAKVERAEAVATTEAMDDIIMASDAVMVARGDLGVEIGDPELVGVQKKLIRRARSFNRIVITATQMMESMIISPMPTRAEVMDVANAVLDGTDAVMLSAETAAGSFPVETVTAMASVCIGAEKEPSINVSNHRMARTFASPEETIAMSTMYAANHMEGVKAMIAMTESGRTALMMSRISSGLPIFAMSRNEDTLNRAALYRGVTPVFFNRDSDAGLDAAKHAMNVLKEAGHLVSGDLVIITQGDVMDIVGSTNNMRILTVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX52</accession>
    <name>D0YX52_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Acyl-coenzyme A dehydrogenase</fullName>
            <ecNumber evidence="6">1.3.8.7</ecNumber>
            <ecNumber evidence="7">1.3.8.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">VDA_001826</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a long-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] = a long-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]</text>
            <dbReference type="Rhea" id="RHEA:17721"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="ChEBI" id="CHEBI:83721"/>
            <dbReference type="ChEBI" id="CHEBI:83727"/>
            <dbReference type="EC" id="1.3.8.8"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a medium-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] = a medium-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]</text>
            <dbReference type="Rhea" id="RHEA:14477"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="ChEBI" id="CHEBI:83723"/>
            <dbReference type="ChEBI" id="CHEBI:83726"/>
            <dbReference type="EC" id="1.3.8.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Lipid metabolism; fatty acid beta-oxidation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.3.8.7" evidence="6"/>
    <dbReference type="EC" id="1.3.8.8" evidence="7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298778.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001826"/>
    <dbReference type="EnsemblBacteria" id="EEZ40794">
        <property type="protein sequence ID" value="EEZ40794"/>
        <property type="gene ID" value="VDA_001826"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1960">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="760677at2"/>
    <dbReference type="UniPathway" id="UPA00659"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004466">
        <property type="term" value="F:long-chain-acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033539">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA dehydrogenase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015396">
        <property type="entry name" value="DUF1974"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09317">
        <property type="entry name" value="DUF1974"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0274">FAD</keyword>
    <keyword evidence="9" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="13">
        <location>
            <begin position="90"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="12">
        <location>
            <begin position="181"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="11">
        <location>
            <begin position="304"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1974" evidence="14">
        <location>
            <begin position="458"/>
            <end position="742"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00020144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF09317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEZ40794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="758" mass="83128" checksum="6A8B135628C233AA" modified="2010-01-19" version="1">MSTLSKWRQRYISDPAFKTFKKVLPPLSDTEKEAMEAGSVWWDGELFSGSPNWDTLLDYPKPELSSDEKAFIDNQLETLLDMLDDYQIVQHDKDLPAEVWNFLRKEKFFSLIISKKYGGLDFSAYANSTIVTKIATRSLSAAVSVMVPNSLGPGELLSHYGTKEQKDYWLPRLAHGDEIPCFALTGPEAGSDAGSIPDRGEVCYGDFNGKQVLGIKLSWNKRYITLAPVATVLGLAFKLFDPDNLIGDQEELGITCALIPVDHDGVEIGERHNPLGMAFMNGPTRGNDVFIPMDWLIGGQEYAGKGWRMLVECLSAGRGISLPALGTAIGHLTARTTGAYSYVRKQFGTSIGNFEGVAQAMGRIGGLTYLLESARTLTTTALDSGQKPGIVTAIAKYHMTELARVILNDSMDIHAGRAIQLGPMNYIGHHYFGIPVAITVEGANILTRNLMIFGQGATRCHPYVLQEMDAAANPDDKAGAKEFDHLLSSHIGFAVKNVAKSLLNAFSRSRFNSAPVSGETATYYRQLARMSKALAVSADFAMLSLGGELKRRELVSARLGDVLSHLYLASAVLKRYEDEGRQKEDLPFVHYGVTYCLHQCGVAFDQAFANFPVKGVGGLLRTLTFPLGIHYAAPKDELSIEIAKLLMKPGAHRERLTHLCYIGQKEDDAVGLLERAFVALNEVKGIEKKLAKAIRSGAIPRKASLSDKLQIALDEGIITEQERDKIDNAEQLRKKAIQVDHFHPAEFKSGGLQPGRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXB1</accession>
    <name>D0YXB1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Leucyl/phenylalanyl-tRNA--protein transferase</fullName>
            <ecNumber evidence="4">2.3.2.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">L/F-transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Leucyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Phenyalanyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">aat</name>
        <name evidence="5" type="ORF">VDA_001651</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>L-leucyl-tRNA(Leu) + N-terminal L-arginyl-[protein] = H(+) + N-terminal L-leucyl-L-arginyl-[protein] + tRNA(Leu)</text>
            <dbReference type="Rhea" id="RHEA:50416"/>
            <dbReference type="Rhea" id="RHEA-COMP:9613"/>
            <dbReference type="Rhea" id="RHEA-COMP:9622"/>
            <dbReference type="Rhea" id="RHEA-COMP:12672"/>
            <dbReference type="Rhea" id="RHEA-COMP:12673"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:64719"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78494"/>
            <dbReference type="ChEBI" id="CHEBI:133044"/>
            <dbReference type="EC" id="2.3.2.6"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>L-leucyl-tRNA(Leu) + N-terminal L-lysyl-[protein] = H(+) + N-terminal L-leucyl-L-lysyl-[protein] + tRNA(Leu)</text>
            <dbReference type="Rhea" id="RHEA:12340"/>
            <dbReference type="Rhea" id="RHEA-COMP:9613"/>
            <dbReference type="Rhea" id="RHEA-COMP:9622"/>
            <dbReference type="Rhea" id="RHEA-COMP:12670"/>
            <dbReference type="Rhea" id="RHEA-COMP:12671"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:65249"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78494"/>
            <dbReference type="ChEBI" id="CHEBI:133043"/>
            <dbReference type="EC" id="2.3.2.6"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>an N-terminal L-alpha-aminoacyl-[protein] + L-phenylalanyl-tRNA(Phe) = an N-terminal L-phenylalanyl-L-alpha-aminoacyl-[protein] + tRNA(Phe)</text>
            <dbReference type="Rhea" id="RHEA:43632"/>
            <dbReference type="Rhea" id="RHEA-COMP:9668"/>
            <dbReference type="Rhea" id="RHEA-COMP:9699"/>
            <dbReference type="Rhea" id="RHEA-COMP:10636"/>
            <dbReference type="Rhea" id="RHEA-COMP:10637"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78531"/>
            <dbReference type="ChEBI" id="CHEBI:78597"/>
            <dbReference type="ChEBI" id="CHEBI:83561"/>
            <dbReference type="EC" id="2.3.2.6"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the L/F-transferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.6" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298446.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001651"/>
    <dbReference type="EnsemblBacteria" id="EEZ40624">
        <property type="protein sequence ID" value="EEZ40624"/>
        <property type="gene ID" value="VDA_001651"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2360">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1670846at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008914">
        <property type="term" value="F:leucyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3550">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00688">
        <property type="entry name" value="Leu_Phe_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004616">
        <property type="entry name" value="Leu/Phe-tRNA_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042203">
        <property type="entry name" value="Leu/Phe-tRNA_Trfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042221">
        <property type="entry name" value="Leu/Phe-tRNA_Trfase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30098">
        <property type="entry name" value="PTHR30098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03588">
        <property type="entry name" value="Leu_Phe_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00667">
        <property type="entry name" value="aat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 5" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="237" mass="26833" checksum="C8B67FB8BBCF35A4" modified="2010-01-19" version="1">MTIYLPQLSPWDTAFPNPNDAFDEPNGLLAMGGDLSPERLMEAYRNGIFPWYSLDEPILWWSPNPRAGFNPATFLPSKSLRKFQRKTNYTVTINQACHQVIEQCANCRGPEQTWITPEMISAYQRLHDLGYCHSVEVWLNNQLVGGFYGIAIGTIFCGESMFSLADNASKIALWQFCRHFYASGGTSIDCQMMNPHLASLGAEIVTRNEFLLQLSTEREKSVSSHCYQPQQLAIYTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXF5</accession>
    <name>D0YXF5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Oligopeptide transport system permease protein OppC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_001634</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001634"/>
    <dbReference type="EnsemblBacteria" id="EEZ40607">
        <property type="protein sequence ID" value="EEZ40607"/>
        <property type="gene ID" value="VDA_001634"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1173">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025966">
        <property type="entry name" value="OppC_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12911">
        <property type="entry name" value="OppC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="138"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="220"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="269"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="103"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="304" mass="33901" checksum="AB9B64E39752B04C" modified="2010-01-19" version="1">MMLVKKDNVEALEKFSDQLEVEGRSLWQDARIRFMRNKAAMVSLVILCVITLWVSFGPMFSQYAFDDTDWYALHAAPSFGAEGHYFGTDSLGRDLYTRTLVGGRISLMVGILGAFVAVLLGTLYGATSGFIGGKTDRVMMRILEILYSIPFMFFVIVLVTFFGRNIMLIFIAIGAISWLDMARIVRGQTLSLRNKEFIEAAYVSGVSKWGIITRHIVPNVLGIVAVYSTLLVPSMILTESFLSFLGLGVQEPMTSWGALLQEGSQTMEVAIWQLLYPAAFMVVTLFCFNYVGDGLRDALDPKDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXJ0</accession>
    <name>D0YXJ0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001704</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298545.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40675">
        <property type="protein sequence ID" value="EEZ40675"/>
        <property type="gene ID" value="VDA_001704"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5339">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="643653at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010352">
        <property type="entry name" value="DUF945"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06097">
        <property type="entry name" value="DUF945"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="437" mass="47906" checksum="CB0E821F696147A7" modified="2010-01-19" version="1">MWKKAFAGAGAVSIVLCWPFITGQIGERIYLDSIAKNKSPYLTITNEKYDCGYLSSNVISKIVVKDEYKSLFEEDGLPTSWTLDHHIKHGFFHITSDSTVQLTDIERKKADAIWGKDVQPVTLETETALNGNTEFTFTVNPIHYQSELGEKVDSKAFVLSGDMDVNGKGNFQYQLPQFDVTTVAKETMALSGLKGGGDGQFVDQFWIGSQFFDLAAIKLATAEDTQHIQASDIKVTMSNVLSQPKNAVKPTEATEQVTNTNAVSVGQFVTLDGQKFTNFNFKMAFENLNYQAITELSKMTNPADGQLSQQDVDAAAHALDVLVEQGVIFNLEDLSVKTEQGDINSHMKLIVAPGLKNSSQNIAAITKQLTGDLSLVAPKALVDNNPVVAQQIKALKKMGVIEQKENTYDLAMKVEGDYLVLASGAKLPLSMLLIPFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXN2</accession>
    <name>D0YXN2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Oxidoreductase aldo/keto reductase 2 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001729</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298590.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001729"/>
    <dbReference type="EnsemblBacteria" id="EEZ40699">
        <property type="protein sequence ID" value="EEZ40699"/>
        <property type="gene ID" value="VDA_001729"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4989">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1367386at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="19"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="302" mass="34168" checksum="ECB42573161C260F" modified="2010-01-19" version="1">MISKEKCALNGPLLSEFIQGYWRLASWNMSVEERIAFINQHLELGISSVDHADIYGDYRCETLFGEALHRSPLLRSQLEIITKCDIKLCSEHYPSRKINHYDTSFEHITSSVEASLRNLQTDYIDMLLIHRPDALMNADEVAHAFSSLKDQGKVLHFGVSNFTPSQFSLLQSRLDFQLVTNQVEINPMNFGVVDDGTLDLLQQLRIRPMAWSCLAGGELFNGQTEQAVRLRAELLAIAQEVGAESVDQVIYAWVRQLPSKPLAIIGSGKIERVRSALASQKIQLTREQWYRIWVASKGHGVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXZ9</accession>
    <name>D0YXZ9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC-type tungstate transport system ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_002162</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002162"/>
    <dbReference type="EnsemblBacteria" id="EEZ41130">
        <property type="protein sequence ID" value="EEZ41130"/>
        <property type="gene ID" value="VDA_002162"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1122">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="7"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="39"/>
            <end position="46"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="235" mass="26549" checksum="CE41BAD69A7A942D" modified="2010-01-19" version="1">MMSQVSLQAHDLSMRFKDRLLFHVQQLNINPQDAIYLSGDNGVGKTTLLKILAGLQKPTTGKVNLQNSRFLRRLLRGHYEGGVIYMHQTPYMFDGTVFDNVCYGLKYAIKDRQLRRNEAIKALRMVGLETLADEHISVLSGGERQRVAMARAWVLKPSVLLMDESSASLDSESILRQVVLAQDLLNRGTSLVITSHQQNALTALCRRHWVINDTKLVERADLQLVTEDNNNNAYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY15</accession>
    <name>D0YY15_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002178</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299597.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002178"/>
    <dbReference type="EnsemblBacteria" id="EEZ41146">
        <property type="protein sequence ID" value="EEZ41146"/>
        <property type="gene ID" value="VDA_002178"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG50334IN">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1449874at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021316">
        <property type="entry name" value="DUF2913"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11140">
        <property type="entry name" value="DUF2913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="215" mass="24279" checksum="3FB37B73F7660816" modified="2010-01-19" version="1">MTRFYNEIYTVVTTGLSELRESQEAGKTPKNPVSETLYLSNWVTKAIKQQRFDTCVAKVLLSWQQQSRTMGKNAQLTTSFEHIASTYGKLTDAEGNSTNISNDTIHALYQDLSDTGWLVTTEYEVNRKVTHKTDGQASLVVCVKQYQQALSESGELIRPISLYVRGDVKQLVDMAYKHGLLLFKVTDYKSLVKYHGEYIVYPANNGPQLPELPTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY53</accession>
    <name>D0YY53_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">[NiFe] hydrogenase nickel incorporation-associated protein HypB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002216</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299667.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002216"/>
    <dbReference type="EnsemblBacteria" id="EEZ41184">
        <property type="protein sequence ID" value="EEZ41184"/>
        <property type="gene ID" value="VDA_002216"/>
    </dbReference>
    <dbReference type="GeneID" id="57341635"/>
    <dbReference type="eggNOG" id="COG0378">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1134430at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051604">
        <property type="term" value="P:protein maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05390">
        <property type="entry name" value="HypB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003495">
        <property type="entry name" value="CobW/HypB/UreG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004392">
        <property type="entry name" value="Hyd_mat_HypB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30134">
        <property type="entry name" value="PTHR30134"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02492">
        <property type="entry name" value="cobW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00073">
        <property type="entry name" value="hypB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="cobW" evidence="2">
        <location>
            <begin position="63"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="245" mass="27528" checksum="F142D7DE27F25640" modified="2010-01-19" version="1">MCQDCGCSLPRAGHHHHHDHNLQSNPQLNDKKTLSVIHKILDKNDMEAAHNRAHFEANNVTAFNLMSSPGSGKTTLLEHLQQCTELTYAVVEGDLETSRDADRLKAAGIEAYQIQTGSACHLDAFMVHGALHHIDLEKLDICFVENVGNLVCPASYDVGTHKNIVLVSIPEGDDKIEKYPVMFRRADLVLITKCDLMPYFDFDMEDAYAQLRKLNPEVEVMQISVKDIDTLKPLAQWLQNNLITK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY64</accession>
    <name>D0YY64_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA transformation protein TfoX</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002227</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299691.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002227"/>
    <dbReference type="EnsemblBacteria" id="EEZ41195">
        <property type="protein sequence ID" value="EEZ41195"/>
        <property type="gene ID" value="VDA_002227"/>
    </dbReference>
    <dbReference type="GeneID" id="57341620"/>
    <dbReference type="eggNOG" id="COG3070">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1803592at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007077">
        <property type="entry name" value="TfoX_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007076">
        <property type="entry name" value="TfoX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026256">
        <property type="entry name" value="TfoX_Sxy"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04994">
        <property type="entry name" value="TfoX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04993">
        <property type="entry name" value="TfoX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028788">
        <property type="entry name" value="TfoX_Sxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TfoX_N" evidence="1">
        <location>
            <begin position="12"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="TfoX_C" evidence="2">
        <location>
            <begin position="115"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="196" mass="22147" checksum="88F445C8EBBE601E" modified="2010-01-19" version="1">MDKPVLKNTLKLFECFGRIKSRSMFGGFGIFAGDTMFALVVNNTLHLRANCNNEGEFKKLGLKPYVYYKKGFPVVTKHYAIPDNWWDDTQCLIKQGELSLQAAEKDKESKSKAIPNRIKDLPNLRLTNERMLKKAGIETVEQLFAVGALDAFKALQSSQGDSLNLELLWALEGAISGQHWSVITEQRRHELLSSLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYH0</accession>
    <name>D0YYH0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fructosamine kinase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002333</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the fructosamine kinase family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299897.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002333"/>
    <dbReference type="EnsemblBacteria" id="EEZ41301">
        <property type="protein sequence ID" value="EEZ41301"/>
        <property type="gene ID" value="VDA_002333"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3001">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1457558at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016477">
        <property type="entry name" value="Fructo-/Ketosamine-3-kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12149">
        <property type="entry name" value="PTHR12149"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03881">
        <property type="entry name" value="Fructosamin_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006221">
        <property type="entry name" value="Ketosamine-3-kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR006221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="288" mass="33328" checksum="8002D88BD5D613E2" modified="2010-01-19" version="1">MWQGISNQLSEQLGYSFKITEKEVLTGSEVNQCYCISDGNERFFLKLNTRDNLVIFETEAESLRILNEACCVQVPQFVHMGTCKDKAFLVLNYLPTKPLDSHSAYELGQNLASQHLWGEQIEYGFDFDNYIGLTPQPNKWRRKWCRFFAEQRIAWQLQLCEEKDISFGNIDTITSNVIQCLLSHQPKPSLLHGDLCYANSALTVSGPIIFDPATYWGDRECDIATAELFAQFPPEFYQGYNSIYPLDENYGQRKELYQLYYLLNQSYLFGGCYIEKARQIINKLKLAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYH6</accession>
    <name>D0YYH6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="15">PTS system glucose-specific II BC component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">VDA_002339</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299918.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002339"/>
    <dbReference type="EnsemblBacteria" id="EEZ41307">
        <property type="protein sequence ID" value="EEZ41307"/>
        <property type="gene ID" value="VDA_002339"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1263">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1264">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2035550at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008982">
        <property type="term" value="F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00212">
        <property type="entry name" value="PTS_IIB_glc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036878">
        <property type="entry name" value="Glu_permease_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018113">
        <property type="entry name" value="PTrfase_EIIB_Cys"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003352">
        <property type="entry name" value="PTS_EIIC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013013">
        <property type="entry name" value="PTS_EIIC_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001996">
        <property type="entry name" value="PTS_IIB_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00367">
        <property type="entry name" value="PTS_EIIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02378">
        <property type="entry name" value="PTS_EIIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55604">
        <property type="entry name" value="SSF55604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00826">
        <property type="entry name" value="EIIB_glc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51098">
        <property type="entry name" value="PTS_EIIB_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01035">
        <property type="entry name" value="PTS_EIIB_TYPE_1_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51103">
        <property type="entry name" value="PTS_EIIC_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0598">Phosphotransferase system</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="58"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="93"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="147"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="191"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="217"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="302"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="328"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="351"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="380"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="407"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="domain" description="PTS EIIC type-1" evidence="14">
        <location>
            <begin position="2"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="domain" description="PTS EIIB type-1" evidence="13">
        <location>
            <begin position="458"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphocysteine intermediate; for EIIB activity" evidence="11">
        <location>
            <position position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEZ41307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="536" mass="58317" checksum="FB5DA1A03CF8DABA" modified="2010-01-19" version="1">MNSLFSSLQKIGRAFMLPIAVLPMAGILLGIGGAFTSGPLIETYHLAFLAPGTPANHILQLCFKAGLFVFENLPLLFAVGVAIGMANNNKETAALSAVIGFLLFQTVIGALLSFQGITPESVTTQALIAAGKNATEAAGIASMYTHVLGIFTLQTGVFGGIACGLLSAFITNKFSHKQLPDYLAFFSGNRLVPVMTMLFFFPLAAIFPYIWPTIFQGIVHAGEAFSAMGYIGTFFYGAAMRLLNVFGLHHAIYPLFWYTELGGVQEVAGQLVSGGQKIFFAQLADPTVTHFSSEATRTMTGGFLPMMFGLPAAALAMYRCADDKNKQLVKGILVSAALTSILTGITEPLEFTFLFVAPALYVIHAIFEGIAYMLMHLLDVAVGITFSRGLIDFTFFGLLQGTAKTSYQWILILGPLYSLAYYFIFSFMIRKFNYSTPGRNQAENKLYTRKDLDGKKQSTLTTEIVEKLGGVDNIETIDACITRLRITVKDPNKVASDDVWRSLDAKGVIRSGKGIQIIYGTQAEIYKNQIIEQYGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYJ8</accession>
    <name>D0YYJ8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphoribosylaminoimidazole-succinocarboxamide synthase</fullName>
            <ecNumber evidence="7">6.3.2.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">SAICAR synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">purC</name>
        <name evidence="9" type="ORF">VDA_002361</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + ATP + L-aspartate = (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate + ADP + 2 H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:22628"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58443"/>
            <dbReference type="ChEBI" id="CHEBI:77657"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the SAICAR synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.6" evidence="7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299955.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002361"/>
    <dbReference type="EnsemblBacteria" id="EEZ41329">
        <property type="protein sequence ID" value="EEZ41329"/>
        <property type="gene ID" value="VDA_002361"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0152">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1345271at2"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00131"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004639">
        <property type="term" value="F:phosphoribosylaminoimidazolesuccinocarboxamide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00137">
        <property type="entry name" value="SAICAR_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028923">
        <property type="entry name" value="SAICAR_synt/ADE2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014106">
        <property type="entry name" value="SAICAR_synthase_Vibrio-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018236">
        <property type="entry name" value="SAICAR_synthetase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01259">
        <property type="entry name" value="SAICAR_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02735">
        <property type="entry name" value="purC_vibrio"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01057">
        <property type="entry name" value="SAICAR_SYNTHETASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAICAR_synt" evidence="8">
        <location>
            <begin position="46"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="367" mass="41648" checksum="7EF8ED096FD5D65C" modified="2010-01-19" version="1">MSLADQVLAVNDDLPIRTHQPVHSGKVRSVYWLTPEDSRRLIQEKNYNVQPDAELATMVISDRISAFDCIWHAEGGLNGVPGKGAALNAISNHWFTLFKQHNLADSHILDIPHPFVWIVQKAKPVKVEAICRQYITGSMWRAYEKGERNFCGIELPERLEKDQKLPELLITPSTKGILTGIPGVPEVDDVNVTRQDLENNLAAFNFQDKADIATYEHMLKAGFTVISDELKQLDQIFVDTKFEFGYVTDANGSEKLIYMDEVGTPDSSRIWDGAAYRNGKIVENSKEDFRQVLLNYFDDPDILLNKDRMDERFALARDNALPQETLMDISRIYIGIAEKITGQKIVLSQNPKQEIIKILNDQYGLID</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYP7</accession>
    <name>D0YYP7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Beta-D-galactosidase beta subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002410</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300040.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002410"/>
    <dbReference type="EnsemblBacteria" id="EEZ41378">
        <property type="protein sequence ID" value="EEZ41378"/>
        <property type="gene ID" value="VDA_002410"/>
    </dbReference>
    <dbReference type="GeneID" id="57341384"/>
    <dbReference type="eggNOG" id="COG2731">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1857569at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004375">
        <property type="entry name" value="NanQ/TabA/YiaL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037012">
        <property type="entry name" value="NanQ/TabA/YiaL_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34986">
        <property type="entry name" value="PTHR34986"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04074">
        <property type="entry name" value="DUF386"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="150" mass="17636" checksum="E66BB0D3CB48FD04" modified="2010-01-19" version="1">MIVLDNLEQFKSVYRNGRKWNRCVEAINNISNIKDGVMHSIGDSLVYMVEDGTAKETENFVGHRRYFDVHYYLEGRETVEFAKKDQLTLTQAYRDETDREYLQGQGETRELTEGQVVIFENDEAYRFCGDNRVRKVVLKVTIEDGYFLNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYQ2</accession>
    <name>D0YYQ2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002415</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300048.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002415"/>
    <dbReference type="EnsemblBacteria" id="EEZ41383">
        <property type="protein sequence ID" value="EEZ41383"/>
        <property type="gene ID" value="VDA_002415"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1192">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1868500at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="165"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="196"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="238" mass="26921" checksum="011A170F58563ABD" modified="2010-01-19" version="1">MRDDFIQKTKLALQHRVGNCCSNPDCRRKTTGPNSDHSKASNIGVACHITAASKNGPRYDSDLSSEDRKSVLNGIWLCESCAKMIDVDVVRYPVELLYSWKHQAEAIAKYEYEGQDVPPELLHNGYYCPYCETFVKEGITFCKGCHADICYGLTPNEKGESAKSWGMIGLVSSMLLFMLAPQFLNGMFGFSIQPFFGSGIFAIIFTAVFSFSLMLFMPEREHKERLKQPPRFFKARSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYS6</accession>
    <name>D0YYS6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">N-acetylmannosamine kinase</fullName>
            <ecNumber evidence="1">2.7.1.60</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002439</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.1.60" evidence="1"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300092.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002439"/>
    <dbReference type="EnsemblBacteria" id="EEZ41407">
        <property type="protein sequence ID" value="EEZ41407"/>
        <property type="gene ID" value="VDA_002439"/>
    </dbReference>
    <dbReference type="GeneID" id="57341342"/>
    <dbReference type="eggNOG" id="COG1940">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1130699at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009384">
        <property type="term" value="F:N-acylmannosamine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01125">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="292" mass="30239" checksum="79953CC18F9DE628" modified="2010-01-19" version="1">MKSVLAVDIGGTKIACAIVRDGQVSNRQQIATPSSQQPDAMTEALRQLLTPYIGQVEQVAVASTGIIDHGILKALNPANLGGLNHYPLQQEIIAIMGCDVDVINDAQAAAWAEFKALEQPVNNMAFITVSTGVGAGIVLNGQLQVGPRGIAGHAGHTVADPHGPRCGCGRIGCVEAIASGTAIAKQTSQRWGEECTGKEAYQAFLAGDPHATFCVENSAKAIANLIADLTITLDLDTVTLGGSVGLAQGYRELVAAQLAELPAVYRPKLVAAKTQADAGLVGVALWVNETNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYT6</accession>
    <name>D0YYT6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Carboxy-S-adenosyl-L-methionine synthase</fullName>
            <shortName evidence="1">Cx-SAM synthase</shortName>
            <ecNumber evidence="1">2.1.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">cmoA</name>
        <name evidence="4" type="ORF">VDA_002449</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>prephenate + S-adenosyl-L-methionine = 3-phenylpyruvate + carboxy-S-adenosyl-L-methionine + H2O</text>
            <dbReference type="Rhea" id="RHEA:51692"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:18005"/>
            <dbReference type="ChEBI" id="CHEBI:29934"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:134278"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.3.-" evidence="1"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300112.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002449"/>
    <dbReference type="EnsemblBacteria" id="EEZ41417">
        <property type="protein sequence ID" value="EEZ41417"/>
        <property type="gene ID" value="VDA_002449"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1739932at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016743">
        <property type="term" value="F:carboxyl- or carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904047">
        <property type="term" value="F:S-adenosyl-L-methionine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01589">
        <property type="entry name" value="Cx_SAM_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005271">
        <property type="entry name" value="CmoA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43861:SF2">
        <property type="entry name" value="PTHR43861:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006325">
        <property type="entry name" value="MeTrfase_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00740">
        <property type="entry name" value="TIGR00740"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="3">
        <location>
            <begin position="60"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="1 2">
        <location>
            <begin position="64"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="1 2">
        <location>
            <begin position="89"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="1 2">
        <location>
            <begin position="117"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1 2">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1 2">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR006325-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="242" mass="27203" checksum="86DEB7D6CF50F7CA" modified="2010-01-19" version="1">MAGHDNIFAAPIEKIGDFTFDARVAEVFPDMIQRSVPGYSNIISAIGMLAERFAKPHSKIYDLGCSLGAATLSMRRHIEQEGCQIIAVDNSSAMVERCRLLVNAYRSDTPVNVIEADIREVEIEEASVVVLNFTLQFLAPDDRQTLLEKIYAGLRPGGILILSEKYVFDDETAHELLIDLHHDFKRANGYSELEISQKRSAIENVMLPDSIQTHRDRLSQIGFSSVEVWFQCFNFGSMFAIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ03</accession>
    <name>D0YZ03_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">N-acetylglucosamine-6-phosphate deacetylase</fullName>
            <ecNumber evidence="8">3.5.1.25</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_002516</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="6">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the metallo-dependent hydrolases superfamily. NagA family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.25" evidence="8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002516"/>
    <dbReference type="EnsemblBacteria" id="EEZ41484">
        <property type="protein sequence ID" value="EEZ41484"/>
        <property type="gene ID" value="VDA_002516"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1820">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047419">
        <property type="term" value="F:N-acetylgalactosamine-6-phosphate deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008448">
        <property type="term" value="F:N-acetylglucosamine-6-phosphate deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006044">
        <property type="term" value="P:N-acetylglucosamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00854">
        <property type="entry name" value="NagA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003764">
        <property type="entry name" value="GlcNAc_6-P_deAcase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11113:SF14">
        <property type="entry name" value="PTHR11113:SF14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038994">
        <property type="entry name" value="NagA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00221">
        <property type="entry name" value="nagA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="7">
        <location>
            <begin position="37"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="202"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="289"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="4">
        <location>
            <position position="256"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="210"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR038994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR038994-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR038994-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR038994-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ41484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="364" mass="39354" checksum="91BDBA939F7A3A13" modified="2010-01-19" version="1">MLNNHAVIVDGVNIHAVCPVAELPQDIKTIDLNGANLTPGFIDVQLNGCGGVMFNDEINADTIHTMHRANIKSGCTSFLPTLITSSDEDMKAAIKAQRDYEAKYQNQSLGLHLEGPYLNVMKKGIHNIDYIRTSDDAMINTICENADVVTKVTLAPEQNDHAHIQKLVEAGVVVSAGHTNATYVEARKGFASGITFATHLFNAMTPIAGREPGMVGAIYDTPEVYTGIIADGFHVDYANIRMAHKMKGEKLVLVTDATAPAGANMDHFIFVGKKVYYRDGKCVDENGTLGGSALTMIEAVQNCVEHVGIALDEAIRMATLYPARAIGVDKKLGAVKQGMVANLTVFDRDYNVQATVVNGEYEQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ05</accession>
    <name>D0YZ05_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative glutathione-regulated potassium-efflux system protein KefB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_002518</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300240.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002518"/>
    <dbReference type="EnsemblBacteria" id="EEZ41486">
        <property type="protein sequence ID" value="EEZ41486"/>
        <property type="gene ID" value="VDA_002518"/>
    </dbReference>
    <dbReference type="GeneID" id="57341253"/>
    <dbReference type="eggNOG" id="COG1226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4651">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="941006at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015299">
        <property type="term" value="F:solute:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003148">
        <property type="entry name" value="RCK_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02254">
        <property type="entry name" value="TrkA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51201">
        <property type="entry name" value="RCK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0050">Antiport</keyword>
    <keyword evidence="4" id="KW-0406">Ion transport</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="74"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="167"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="197"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="271"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="303"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="333"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="RCK N-terminal" evidence="7">
        <location>
            <begin position="387"/>
            <end position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ41486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="529" mass="57715" checksum="8F19029020FFD0BD" modified="2010-01-19" version="1">MEIVFIITAFVAGFIALRCKLPPLVGFLIAGFFLNSFGYHSTDALTTFADLGVTLLLFTIGLKLDVKTLLAKEIWGGATLHNLLSTLLFTLCLKGLQLLGLNMLAGLDMGQLALMGFALSFSSTVFAIKALQEKGELNATYGTLAIGVLVMQDIFAVVFLTASTGKMPEITALGLFALPLLRPLFYRILDKAGHGEMLVLYGIFLALVAGAGLFESVGMKPDLGALILGMMLASHPKASELSKSLFNIKEILLVCFFLNIGLAETPTIDGLLMALVLMLILPLKGILYYLVFHLFRFRVRTSLLGTLTLFNYSEFGLIVGGVAYKLGWLPGNFLVAIAIAVSLSFLVAAAVTSAGHKIYSQSSRWLKEFAPEQLNSGDKLIDLGSARIMILGMGRIGSGAYDELTERYGHQVIGVETREDSAEQHKQEGRNVICGDATDPDFWARVIKRRNIDLILLAMPNSQANTFALEQIRLRDYQGQIAAIAKYSEDEQWLIEQGVDAAFNIYSEAGSGFARHVCEHLDPQIQRIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ40</accession>
    <name>D0YZ40_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Accessory colonization factor AcfA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002553</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300310.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002553"/>
    <dbReference type="EnsemblBacteria" id="EEZ41521">
        <property type="protein sequence ID" value="EEZ41521"/>
        <property type="gene ID" value="VDA_002553"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3637">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1160706at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027385">
        <property type="entry name" value="OMP_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13505">
        <property type="entry name" value="OMP_b-brl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019258" evidence="1">
        <location>
            <begin position="19"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="OMP_b-brl" evidence="2">
        <location>
            <begin position="6"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="212" mass="23901" checksum="3D7653160F109208" modified="2010-01-19" version="1">MKKHLLAALLCTSSSAMAAPYVGLDLGLSTFSHDYQTHFSADNKTVSPNDSGMVLNGYVGYRWDEFGLELGYRHFDELDGSSSQFMGNVDGFRHEREWDADLKVSQITLKPVYFYTLTDRVELKTGLGLTYTQYDYRSGSSDEYELITNDDIEHNVNRAGGENKKNNEFGVIASVGVDYRIWQQLHIGAGVDYYADSQANAATFMLTSRYQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZA5</accession>
    <name>D0YZA5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein-glutamate O-methyltransferase</fullName>
            <ecNumber evidence="3">2.1.1.80</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_002618</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-glutamyl-[protein] + S-adenosyl-L-methionine = [protein]-L-glutamate 5-O-methyl ester + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:24452"/>
            <dbReference type="Rhea" id="RHEA-COMP:10208"/>
            <dbReference type="Rhea" id="RHEA-COMP:10311"/>
            <dbReference type="ChEBI" id="CHEBI:29973"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:82795"/>
            <dbReference type="EC" id="2.1.1.80"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.1.1.80" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300506.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002618"/>
    <dbReference type="EnsemblBacteria" id="EEZ41586">
        <property type="protein sequence ID" value="EEZ41586"/>
        <property type="gene ID" value="VDA_002618"/>
    </dbReference>
    <dbReference type="GeneID" id="57341132"/>
    <dbReference type="eggNOG" id="COG1352">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1378151at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008983">
        <property type="term" value="F:protein-glutamate O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.155.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022642">
        <property type="entry name" value="CheR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000780">
        <property type="entry name" value="CheR_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022641">
        <property type="entry name" value="CheR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036804">
        <property type="entry name" value="CheR_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01739">
        <property type="entry name" value="CheR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03705">
        <property type="entry name" value="CheR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00996">
        <property type="entry name" value="CHERMTFRASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00138">
        <property type="entry name" value="MeTrc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50123">
        <property type="entry name" value="CHER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CheR-type methyltransferase" evidence="7">
        <location>
            <begin position="1"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ41586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="274" mass="30893" checksum="789DEF41901099DF" modified="2010-01-19" version="1">MTTTVNDKDYAEFCRFLEAQCGIVLGDSKQYLVRSRLSPLVSRFSLASISDLIQSVLVGRNRELRVAAVDAMTTNETLWFRDIYPYTVLTERIFPELAAHKRPLKIWSAASSSGQEPYSIAMSVLETQMKKPGLLSGVHITATDISQTMLDMCRTGVYDNLALGRGLSPERRRMFFDDNGDGRMKINDKVKRLVQFRAQNLKDSYALLGKFDVIFCRNVLIYFSPEMKAKVLNQMAQSLNPGGYLLLGASESLTGLTDKFEMIRCNPGIIYKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZA7</accession>
    <name>D0YZA7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Flagella basal body P-ring formation protein FlgA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_002620</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the FlgA family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300512.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002620"/>
    <dbReference type="EnsemblBacteria" id="EEZ41588">
        <property type="protein sequence ID" value="EEZ41588"/>
        <property type="gene ID" value="VDA_002620"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1261">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1521961at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044780">
        <property type="term" value="P:bacterial-type flagellum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017585">
        <property type="entry name" value="Flag_basal_body_FlgA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039246">
        <property type="entry name" value="Flagellar_FlgA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041231">
        <property type="entry name" value="FlgA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013974">
        <property type="entry name" value="SAF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36307">
        <property type="entry name" value="PTHR36307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13144">
        <property type="entry name" value="ChapFlgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17656">
        <property type="entry name" value="ChapFlgA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00858">
        <property type="entry name" value="SAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03170">
        <property type="entry name" value="flgA_cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1005">Bacterial flagellum biogenesis</keyword>
    <keyword evidence="9" id="KW-0966">Cell projection</keyword>
    <keyword evidence="9" id="KW-0969">Cilium</keyword>
    <keyword evidence="9" id="KW-0282">Flagellum</keyword>
    <keyword evidence="5 7" id="KW-0574">Periplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005126059" description="Flagella basal body P-ring formation protein FlgA" evidence="7">
        <location>
            <begin position="25"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="SAF" evidence="8">
        <location>
            <begin position="109"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="231" mass="25285" checksum="EDD232EB24D6DF3D" modified="2010-01-19" version="1">MRFKFIPSIIGLVSVIFSNNMSFAADIDLETIRHSAEAFVQTQITPPKEGELSIEAAQLDSRLRFSHCSEPLETSLPGKQEINNNATVLVRCNHENWQVYVPVRVQLLLPRVVASVPLGRGMVLSQNNLTVALIESRFQRGAIYQSPQALFGAKVKRNVKIGEAVQANDICMVCRNDKVVISAGQPGLKIITQGTALSDGTLGEQIRVKNNRSNKIISAQVSAVGEVDVSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZF6</accession>
    <name>D0YZF6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">tRNA sulfurtransferase</fullName>
            <ecNumber evidence="11">2.8.1.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Sulfur carrier protein ThiS sulfurtransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Thiamine biosynthesis protein ThiI</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">tRNA 4-thiouridine synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">thiI</name>
        <name evidence="15" type="ORF">VDA_002669</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>[ThiI sulfur-carrier protein]-S-sulfanyl-L-cysteine + a uridine in tRNA + ATP + H(+) + 2 reduced [2Fe-2S]-[ferredoxin] = [ThiI sulfur-carrier protein]-L-cysteine + a 4-thiouridine in tRNA + AMP + diphosphate + 2 oxidized [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:24176"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:13337"/>
            <dbReference type="Rhea" id="RHEA-COMP:13338"/>
            <dbReference type="Rhea" id="RHEA-COMP:13339"/>
            <dbReference type="Rhea" id="RHEA-COMP:13340"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:61963"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:136798"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.8.1.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>[sulfur-carrier protein ThiS]-C-terminal Gly-Gly-AMP + AH2 + S-sulfanyl-L-cysteinyl-[cysteine desulfurase] = [sulfur-carrier protein ThiS]-C-terminal Gly-NH-CH2-C(O)SH + A + AMP + H(+) + L-cysteinyl-[cysteine desulfurase]</text>
            <dbReference type="Rhea" id="RHEA:43340"/>
            <dbReference type="Rhea" id="RHEA-COMP:12157"/>
            <dbReference type="Rhea" id="RHEA-COMP:12158"/>
            <dbReference type="Rhea" id="RHEA-COMP:12908"/>
            <dbReference type="Rhea" id="RHEA-COMP:12910"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:61963"/>
            <dbReference type="ChEBI" id="CHEBI:90618"/>
            <dbReference type="ChEBI" id="CHEBI:90619"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="11">Cofactor biosynthesis; thiamine diphosphate biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the ThiI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.4" evidence="11"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300659.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002669"/>
    <dbReference type="EnsemblBacteria" id="EEZ41637">
        <property type="protein sequence ID" value="EEZ41637"/>
        <property type="gene ID" value="VDA_002669"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0301">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0607">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="773697at2"/>
    <dbReference type="UniPathway" id="UPA00060"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004810">
        <property type="term" value="F:tRNA adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140741">
        <property type="term" value="F:tRNA U4 sulfurtransferase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052837">
        <property type="term" value="P:thiazole biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034227">
        <property type="term" value="P:tRNA thio-modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01712">
        <property type="entry name" value="ThiI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00021">
        <property type="entry name" value="ThiI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026340">
        <property type="entry name" value="Thiazole_biosynth_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020536">
        <property type="entry name" value="ThiI_AANH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004114">
        <property type="entry name" value="THUMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003720">
        <property type="entry name" value="tRNA_STrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02568">
        <property type="entry name" value="ThiI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02926">
        <property type="entry name" value="THUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00981">
        <property type="entry name" value="THUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04271">
        <property type="entry name" value="ThiI_C_thiazole"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00342">
        <property type="entry name" value="TIGR00342"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51165">
        <property type="entry name" value="THUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10 11" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11 12" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="8 11" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="4 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 11" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="THUMP" evidence="14">
        <location>
            <begin position="61"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodanese" evidence="13">
        <location>
            <begin position="404"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine persulfide intermediate" evidence="11">
        <location>
            <position position="456"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="183"/>
            <end position="184"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="265"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="287"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="296"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="11">
        <location>
            <begin position="344"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEZ41637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="482" mass="54402" checksum="9FF834F71676B606" modified="2010-01-19" version="1">MKFIVKPHPEIFVKSDSVRKRFIKILESNLRIILKRQSDTVSIYNRRFHLEVTEPDTAKREAIVATLTQTPGIHHVLEVQQMEFKDLHDIYEQTFALVAPNLEGKTFCVRAKRTGQHDFTSIELERYVGGGLNQNIETARVKLKNPDVTVNIEVERENLNLVLERHQGLGGFPLGTQEDVLSLISGGFDSGVSSYLHIKRGSKVHYCFFNLGGPAHEIGVKQVSHFLWNKYGSSAKVKFIAVDFEPVVAEILEKVDDGQMGVVLKRMFMRAAGQVAEHFGIQALVTGEALGQVSSQTLTNLRHIDGVTDTLILRPLINWDKEDIINMARHIGTEDFAKTMPEFCGVISKKPTVKAVKEKLETEEAKFDFSILDRVVKEARVMDIRDIEKQSQEQAPEVELVSEIAGGAVVLDIRSPDEEDESPLEIDGVEVKHLPFYKLATQFGDLPQDKTYLLYCARGVMSRLQALYLKENGFDNVKVYRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZP2</accession>
    <name>D0YZP2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative transcriptional regulator SorC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002755</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SorC transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300913.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002755"/>
    <dbReference type="EnsemblBacteria" id="EEZ41723">
        <property type="protein sequence ID" value="EEZ41723"/>
        <property type="gene ID" value="VDA_002755"/>
    </dbReference>
    <dbReference type="GeneID" id="57340968"/>
    <dbReference type="eggNOG" id="COG2390">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1390156at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007324">
        <property type="entry name" value="Sugar-bd_dom_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04198">
        <property type="entry name" value="Sugar-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sugar-bind" evidence="2">
        <location>
            <begin position="64"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="324" mass="35539" checksum="D3279FA11CEFF012" modified="2010-01-19" version="1">MSTAPTDHVDSDLLTEIAIAYYQDGATQEEISQKFGMSRAKVGRLLRRAREEGVVEITVKYHPVFSEKLEQQLIERFNLKRALIALDQPDDETQRQQVASLVSSYLSSVLTDDMVVTVGQGRNVAAIAGHVGVVPHRNCRFVCGIGGTHRSGNAINADHICRQLAKKYDGISETLYAPAYVEDITVKEAFMKNGTVKETLDRARRADVALVGVGDMNENSHMVKLGWFSPQEIVEARIRKGVVGDIAGYDFFDSQGHKADTMMSDRVIGLSMEELRHIPTVVVIAAENSKALALLGALRSGVVDVLATNVSNALTILNLDQQMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZU8</accession>
    <name>D0YZU8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">Thymidine phosphorylase</fullName>
            <ecNumber evidence="4 7">2.4.2.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">TdRPase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">deoA</name>
        <name evidence="9" type="ORF">VDA_002811</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>phosphate + thymidine = 2-deoxy-alpha-D-ribose 1-phosphate + thymine</text>
            <dbReference type="Rhea" id="RHEA:16037"/>
            <dbReference type="ChEBI" id="CHEBI:17748"/>
            <dbReference type="ChEBI" id="CHEBI:17821"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57259"/>
            <dbReference type="EC" id="2.4.2.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Pyrimidine metabolism; dTMP biosynthesis via salvage pathway; dTMP from thymine: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 7">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.4" evidence="4 7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301076.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002811"/>
    <dbReference type="EnsemblBacteria" id="EEZ41779">
        <property type="protein sequence ID" value="EEZ41779"/>
        <property type="gene ID" value="VDA_002811"/>
    </dbReference>
    <dbReference type="GeneID" id="57340910"/>
    <dbReference type="eggNOG" id="COG0213">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1724909at2"/>
    <dbReference type="UniPathway" id="UPA00578">
        <property type="reaction ID" value="UER00638"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004645">
        <property type="term" value="F:1,4-alpha-oligoglucan phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016154">
        <property type="term" value="F:pyrimidine-nucleoside phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009032">
        <property type="term" value="F:thymidine phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006206">
        <property type="term" value="P:pyrimidine nucleobase metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046104">
        <property type="term" value="P:thymidine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1030.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01628">
        <property type="entry name" value="Thymid_phosp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000312">
        <property type="entry name" value="Glycosyl_Trfase_fam3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017459">
        <property type="entry name" value="Glycosyl_Trfase_fam3_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036320">
        <property type="entry name" value="Glycosyl_Trfase_fam3_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035902">
        <property type="entry name" value="Nuc_phospho_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036566">
        <property type="entry name" value="PYNP-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013102">
        <property type="entry name" value="PYNP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018090">
        <property type="entry name" value="Pyrmidine_PPas_bac/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017872">
        <property type="entry name" value="Pyrmidine_PPase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000053">
        <property type="entry name" value="Thymidine/pyrmidine_PPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013465">
        <property type="entry name" value="Thymidine_Pase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10515">
        <property type="entry name" value="PTHR10515"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02885">
        <property type="entry name" value="Glycos_trans_3N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00591">
        <property type="entry name" value="Glycos_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07831">
        <property type="entry name" value="PYNP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000478">
        <property type="entry name" value="TP_PyNP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00941">
        <property type="entry name" value="PYNP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47648">
        <property type="entry name" value="SSF47648"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52418">
        <property type="entry name" value="SSF52418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54680">
        <property type="entry name" value="SSF54680"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02643">
        <property type="entry name" value="T_phosphoryl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02644">
        <property type="entry name" value="Y_phosphoryl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00647">
        <property type="entry name" value="THYMID_PHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7 9" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PYNP_C" evidence="8">
        <location>
            <begin position="350"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="443" mass="47202" checksum="A0A39562298D8FD4" modified="2010-01-19" version="1">MYLPQEIIRKKRDNIELTKEEINFFIQGVAKDTVSEGQIAAFAMAIYFNDMTMAERVALTCAMRDSGMVIDWSHMNFDGPIVDKHSTGGVGDVTSLMLGPMVAACGGYVPMISGRGLGHTGGTLDKLESIPGYNITPTNEVFGQVTKDAGVAIIGQTGDLAPADKRVYATRDVTATVDNISLITASILSKKLAAGLDALVMDVKVGSGAFMPTYEKSEELAKSIVAVANGAGTRTTALLTDMNQVLASTAGNALEVREAVQFLTGEYRNPRLYEVTMALCAEMLVISGLAQDLAEARTKLQAVLDNGKAAECFGKMVAGLGGPLDFVENYNNYLDTAEIIKPVFAEKTGFASAMDTRGLGMAVVGMGGGRRVAADTIDYAVGLADMIRLGDEVYADTPLAMVHARTEAQWEEAAKAVRANITIADEKPQATPEVYARIRPEDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZY1</accession>
    <name>D0YZY1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">MgtE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_002844</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC41A transporter family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301175.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41812">
        <property type="protein sequence ID" value="EEZ41812"/>
        <property type="gene ID" value="VDA_002844"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2239">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1239195at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006667">
        <property type="entry name" value="SLC41_membr_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036739">
        <property type="entry name" value="SLC41_membr_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01769">
        <property type="entry name" value="MgtE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161093">
        <property type="entry name" value="SSF161093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="108"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="182"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="214"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="248"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="MgtE" evidence="7">
        <location>
            <begin position="142"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ41812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="279" mass="29995" checksum="5ECA5A5930E30AA9" modified="2010-01-19" version="1">MAVMNYAAFSAAQQLDHKDAVAVRNAFLKYSLQEQAELLVKMPISEALAMLHECPLRHVQLLLDRLDEMNEELRMRQLANGLGLICSEAEPTGNYLQNSVFSHVRERIGWIVGLALLGIVSGLIISHYEDTLSQLVLLAIYMPVIAAAGGNTGSQAATLVVRALAMDEIKCRDWVAVLWKEFRIAVALALVIVARVMFFSGHQVLPAGLTLFDVAGAIGVALAIQVTLSTSVGGVLPIIARACNLDPAVLVSPVLASMVDISGMIIYFTTVNKMLGLGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z017</accession>
    <name>D0Z017_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Threonine synthase</fullName>
            <ecNumber evidence="5">4.2.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">VDA_002880</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + O-phospho-L-homoserine = L-threonine + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10840"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57590"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="EC" id="4.2.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 9">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 5/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the threonine synthase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.1" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301265.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002880"/>
    <dbReference type="EnsemblBacteria" id="EEZ41848">
        <property type="protein sequence ID" value="EEZ41848"/>
        <property type="gene ID" value="VDA_002880"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0498">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="428821at2"/>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00065"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004795">
        <property type="term" value="F:threonine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000634">
        <property type="entry name" value="Ser/Thr_deHydtase_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029144">
        <property type="entry name" value="Thr_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037158">
        <property type="entry name" value="Thr_synth_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004450">
        <property type="entry name" value="Thr_synthase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14821">
        <property type="entry name" value="Thr_synth_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00260">
        <property type="entry name" value="thrC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00165">
        <property type="entry name" value="DEHYDRATASE_SER_THR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0456">Lyase</keyword>
    <keyword evidence="8 9" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0791">Threonine biosynthesis</keyword>
    <feature type="domain" description="Thr_synth_N" evidence="11">
        <location>
            <begin position="10"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="PALP" evidence="10">
        <location>
            <begin position="96"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="9">
        <location>
            <position position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR604450-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF14821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ41848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="432" mass="47049" checksum="F2EBF128B4ABF11B" modified="2010-01-19" version="1">MKLVNLKEPQQQVSFSYAVQNGLGRQQGLFFPDTLPIFDDIDALLELDFVTRSSKILSAFIGEELSSQQVSQLVDAAFQFSAPITKVSDNTYALELFHGPTLAFKDFGGRFMAQSLAAVTGDDGKITILTATSGDTGAAVAHAFYGMDNIQVVILYPKGKISPLQEKLFCTLGKNITTVAIDGTFDDCQALVKQAFDDPTLRADIGLNSANSINISRLLAQVCYYFEAVAQLPLTERQELVISVPSGNFGNLTAGLLAKAIGLPVKRFIAATNVNDTVPRYLQTGIWQPKTTIPTISNAMDVSQPNNWPRIEALCQQQGWGLETLGYGAVTDQQSAETLHQLQQLGYLCEPHGAIAYRVLNEQLQPGETGLFLCTAHPAKFKEVVDDILAIDIPLPEPLAKHNVLPLLSLERGNDFADIAAILYSVQPEKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z036</accession>
    <name>D0Z036_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Iron-sulfur cluster insertion protein ErpA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">erpA</name>
        <name evidence="7" type="ORF">VDA_002899</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Required for insertion of 4Fe-4S clusters for at least IspG.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>iron-sulfur cluster</name>
            <dbReference type="ChEBI" id="CHEBI:30408"/>
        </cofactor>
        <text evidence="5">Binds 1 iron-sulfur cluster per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the HesB/IscA family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301299.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002899"/>
    <dbReference type="EnsemblBacteria" id="EEZ41867">
        <property type="protein sequence ID" value="EEZ41867"/>
        <property type="gene ID" value="VDA_002899"/>
    </dbReference>
    <dbReference type="GeneID" id="57340809"/>
    <dbReference type="eggNOG" id="COG0316">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1891602at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.300.12">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01380">
        <property type="entry name" value="Fe_S_insert_ErpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000361">
        <property type="entry name" value="FeS_biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016092">
        <property type="entry name" value="FeS_cluster_insertion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017870">
        <property type="entry name" value="FeS_cluster_insertion_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023063">
        <property type="entry name" value="FeS_cluster_insertion_RrpA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035903">
        <property type="entry name" value="HesB-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01521">
        <property type="entry name" value="Fe-S_biosyn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89360">
        <property type="entry name" value="SSF89360"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00049">
        <property type="entry name" value="TIGR00049"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01152">
        <property type="entry name" value="HESB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0408">Iron</keyword>
    <keyword evidence="4 5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe-S_biosyn" evidence="6">
        <location>
            <begin position="8"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>iron-sulfur cluster</name>
            <dbReference type="ChEBI" id="CHEBI:30408"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>iron-sulfur cluster</name>
            <dbReference type="ChEBI" id="CHEBI:30408"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>iron-sulfur cluster</name>
            <dbReference type="ChEBI" id="CHEBI:30408"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="113" mass="12021" checksum="799A9602C5C9B332" modified="2010-01-19" version="1">MSEAALPLNFSDAAASRVKTLIAEEENPDLKLRVYITGGGCSGFQYGFTFDEKVNEGDMVIENCGVTLVVDPMSLQYLIGGTVDYTDGLEGSRFFVNNPNATTTCGCGASFSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z039</accession>
    <name>D0Z039_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_002902</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301309.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002902"/>
    <dbReference type="EnsemblBacteria" id="EEZ41870">
        <property type="protein sequence ID" value="EEZ41870"/>
        <property type="gene ID" value="VDA_002902"/>
    </dbReference>
    <dbReference type="GeneID" id="57340806"/>
    <dbReference type="eggNOG" id="COG0628">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="944044at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002549">
        <property type="entry name" value="AI-2E-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21716">
        <property type="entry name" value="PTHR21716"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01594">
        <property type="entry name" value="AI-2E_transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="35"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="63"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="163"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="216"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="243"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="277"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="314"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="362" mass="40098" checksum="9BA1F29AC8444B63" modified="2010-01-19" version="1">MSQPFKVESRHWMLVVALVIAGYASYRIIEPYLGPIIMAVIISLLCHPMHEKIRGKMPGSPNIASLLSCTLLTFIIMIPMLVVFSSIVHQGTTFSKESYTWLTDGGAKELFAHPYVQKSFALIDKYSPFKSIDPQEVLQKIASIASQLGSTLLNVSTKLLGDVTNFLMSFILMLFVLFFLLRDHDKMVATVRNVLPLSRSQEDALFSEVQTVAKSAVLGSFMTALAQGVAGGFAMWLCGFPGLFWGSMMAFASFIPVVGTALIWVPATLYLLLLGQWEWALFLTGWGIIVVGSIDNVLRPLLMQGGDSNMNTLLIFFSILGGLQLFGLIGLIYGPIIFGVTLVLFKLYEIEFKDFLEHQDRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z057</accession>
    <name>D0Z057_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Valine--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Valyl-tRNA synthetase</fullName>
            <shortName evidence="8">ValRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">valS</name>
        <name evidence="13" type="ORF">VDA_002920</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-valine + tRNA(Val) = AMP + diphosphate + L-valyl-tRNA(Val)</text>
            <dbReference type="Rhea" id="RHEA:10704"/>
            <dbReference type="Rhea" id="RHEA-COMP:9672"/>
            <dbReference type="Rhea" id="RHEA-COMP:9708"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57762"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78537"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.9"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">The C-terminal coiled-coil domain is crucial for aminoacylation activity.</text>
    </comment>
    <comment type="domain">
        <text evidence="8">ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.9" evidence="8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301359.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002920"/>
    <dbReference type="EnsemblBacteria" id="EEZ41888">
        <property type="protein sequence ID" value="EEZ41888"/>
        <property type="gene ID" value="VDA_002920"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0525">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="32262at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004832">
        <property type="term" value="F:valine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006438">
        <property type="term" value="P:valyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07962">
        <property type="entry name" value="Anticodon_Ia_Val"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.740.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02004">
        <property type="entry name" value="Val_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033705">
        <property type="entry name" value="Anticodon_Ia_Val"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010978">
        <property type="entry name" value="tRNA-bd_arm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037118">
        <property type="entry name" value="Val-tRNA_synth_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019499">
        <property type="entry name" value="Val-tRNA_synth_tRNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002303">
        <property type="entry name" value="Valyl-tRNA_ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11946">
        <property type="entry name" value="PTHR11946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10458">
        <property type="entry name" value="Val_tRNA-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00986">
        <property type="entry name" value="TRNASYNTHVAL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46589">
        <property type="entry name" value="SSF46589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="SSF50677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00422">
        <property type="entry name" value="valS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-synt_1" evidence="10">
        <location>
            <begin position="14"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="domain" description="Anticodon_1" evidence="11">
        <location>
            <begin position="675"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="domain" description="Val_tRNA-synt_C" evidence="12">
        <location>
            <begin position="888"/>
            <end position="946"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="884"/>
            <end position="953"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="8">
        <location>
            <begin position="42"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="8">
        <location>
            <begin position="554"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="557"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF10458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ41888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="953" mass="108037" checksum="AB19BC4DF15CB392" modified="2010-01-19" version="1">MEKTYNPQSIEQALYQRWEEAGYFKPHGDTSKDAYSIMIPPPNVTGSLHMGHAFQDTIMDTLIRCERMKGKNTLWQVGTDHAGIATQMVVERKIAAEEGKTKHDYGRDAFIDKIWEWKGESGGTITKQLRRLGASVDWDRERFTMDAGLSNAVQEVFVRLYEEDLIYRGKRLVNWDPKLHTAISDLEVENKDTKGHMWHFRYPLADGVKTVDGKDYIVVATTRPETMLGDTGVAVNPEDPRYKDLIGKDIILPIVGRRIPIVGDEHADMEKGTGCVKITPAHDFNDYEVGKRHSLPMINILTFNADIRDAAEVFNTNGEPSDAYSTELPAKYHGMERFAARKAIVAEFDELGLLEEIKDHDLQVPYGDRGGVVIEPMLTDQWYVRAAPLAKPAVEAVENGDIKFVPKQYENMYFSWMRDIQDWCISRQLWWGHRIPAWYDNDGNVYVGRTEEEVRENNNLAPVVVLRQDDDVLDTWFSSALWTFGTQGWPENTIDLKTFHPSDVLVTGFDIIFFWVARMIMMTMHFCKDEDGKAQVPFKTVYVTGLIRDENGDKMSKSKGNVLDPIDMIDGIDLESLVAKRTGNMMQPQLAAKIEKNTRKTFENGIEPYGTDALRFTLAAMASTGRDINWDMKRLEGYRNFCNKLWNASRYVLMNTEDQDCGFAAGSELEYSLADKWIESQFELAAKEFNAHIDNFRLDMAANTLYEFIWNQFCDWYLELTKPVLWKGSEAQQRATRRTLITVLEKTLRLAHPVLPYITETIWQSVKPLVDGIEGDTIMLQALPQYDENNFDAKALADIEWVKGFITSIRNLRAEYDIAPSKPLDVMLKATDAQDAARLEANRTVLMSLAKLESLNVLEAGAETPACATALVGKSELMIPMAGLIDKDAELARLAKEIAKTEGEIKRIEGKLGNEGFVAKAPEAVIAKEREKLTGYQEALAKLAEQKETIAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z093</accession>
    <name>D0Z093_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">Pyruvate kinase</fullName>
            <ecNumber evidence="4 12">2.7.1.40</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">VDA_002956</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + pyruvate = ADP + H(+) + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:18157"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.40"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 12">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 5/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the pyruvate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.40" evidence="4 12"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301418.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002956"/>
    <dbReference type="EnsemblBacteria" id="EEZ41924">
        <property type="protein sequence ID" value="EEZ41924"/>
        <property type="gene ID" value="VDA_002956"/>
    </dbReference>
    <dbReference type="GeneID" id="57340734"/>
    <dbReference type="eggNOG" id="COG0469">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1098983at2"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00188"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030955">
        <property type="term" value="F:potassium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004743">
        <property type="term" value="F:pyruvate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00288">
        <property type="entry name" value="Pyruvate_Kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.33.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1380.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001697">
        <property type="entry name" value="Pyr_Knase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011037">
        <property type="entry name" value="Pyrv_Knase-like_insert_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018209">
        <property type="entry name" value="Pyrv_Knase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015793">
        <property type="entry name" value="Pyrv_Knase_brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015795">
        <property type="entry name" value="Pyrv_Knase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036918">
        <property type="entry name" value="Pyrv_Knase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015806">
        <property type="entry name" value="Pyrv_Knase_insert_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11817">
        <property type="entry name" value="PTHR11817"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00224">
        <property type="entry name" value="PK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02887">
        <property type="entry name" value="PK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01050">
        <property type="entry name" value="PYRUVTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50800">
        <property type="entry name" value="SSF50800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52935">
        <property type="entry name" value="SSF52935"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01064">
        <property type="entry name" value="pyruv_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00110">
        <property type="entry name" value="PYRUVATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 12" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="7 12 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="9 12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11 15" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PK" evidence="13">
        <location>
            <begin position="1"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="domain" description="PK_C" evidence="14">
        <location>
            <begin position="356"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEZ41924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="470" mass="50457" checksum="F25A6C1CB6EFC3F1" modified="2010-01-19" version="1">MKKTKIVCTIGPKTESVEVLTKLADAGMNVMRLNFSHGDFEEHGRRISNLREVMKNTGKQLAILLDTKGPEIRTIKLENGEDVALVAGQEFTFTTDTSVVGNKDRVAVTYPGFAKDLNKGNTILVDDGLIEMEVIETTETEVKCTVLNNGDLGENKGVNLPGVSVNLPALAEKDKADLKFGCEQGVDFVAASFIRKADDVREIRELLNANGGENIQIISKIENQEGVDNFDEILELSDGIMVARGDLGVEIPVEEVIFAQKMMIEKCNRARKVVITATQMLDSMIKNPRPTRAEAGDVANAIMDGTDAVMLSGETAKGKYPIEAVSIMAQICSRTDKALKAELGSRLDSPRLRITEAVCKGAVDTAEKLAAPLIVVATEAGKSARSIRKYFPTARILAITTNTKTAAQLCLSKGVTPVIVDSIESTDTFYARGKELALETGLGAKGDIVVMVSGALVPSGTTNTASVHVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z096</accession>
    <name>D0Z096_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Long-chain-fatty-acid--CoA ligase</fullName>
            <ecNumber evidence="2">6.2.1.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002959</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="6.2.1.3" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002959"/>
    <dbReference type="EnsemblBacteria" id="EEZ41927">
        <property type="protein sequence ID" value="EEZ41927"/>
        <property type="gene ID" value="VDA_002959"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1022">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004467">
        <property type="term" value="F:long-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="32"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="299" mass="33837" checksum="93AC94FE39993607" modified="2010-01-19" version="1">MAVARQNCTEPSWLLRKSHALADKMVLSKLREVLGGNIKFMPAGGAKLDATIGRFFHAIGINVKLGYGMTETTATVSCWDDKCFNPDSIGMPMPGAEVKIGDDNEILVRGPMVMRGYYKMPEETANNFTEDGFLKTGDAGHFDEQGNLFITDRIKELMKTSGGKYIAPQVIEGAIGKDHFIEQIAVVADTRKFVSALIVPCFETLEEHARELNIKYQDRLELVKNSQIVELIEKRVADLQKDLARFEQVKKFTLLPKAFSMDHGELTPTQKLRRKVIQDRYHQEIERMYEESHKKASHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0A7</accession>
    <name>D0Z0A7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">PhoH family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_002970</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PhoH family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301438.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002970"/>
    <dbReference type="EnsemblBacteria" id="EEZ41938">
        <property type="protein sequence ID" value="EEZ41938"/>
        <property type="gene ID" value="VDA_002970"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1875">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="445854at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003714">
        <property type="entry name" value="PhoH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02562">
        <property type="entry name" value="PhoH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13638">
        <property type="entry name" value="PIN_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00670">
        <property type="entry name" value="PINc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PINc" evidence="4">
        <location>
            <begin position="7"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="458" mass="51264" checksum="3D699CB5F5274785" modified="2010-01-19" version="1">MDGSTRKLFVLDTNILLHEPLAIYSFQEHDVIVPMTVLEELDRIKDSKRDVSRDARVAIRALEDIFHDATPEQISAGVPLQSQNETGGTIAIFADYEVKETVHAFSDKMGDNRILNSVLFLQQKFAPRDVVLVTKDINMRLRAKGAGVYFVDDYRTDQLIDDVALLSKGFHRFDGSFWAGVAQCDSEKRGMSTCHTLPKHLFENPYPNQYLIDESQDFAARIQEIDAETITVKDLGFERLMHRQAWGISPKNIYQAMALDAMLDPKIDLVILTGPAGCGKTILAMAAALEQVIEKGMYDKILVTRNTPEIAESIGFLPGSEEEKMLPWLGAVTDTLEALHKHDVCTDGSMKYIFDKANIQFKSINFMRGRSIQNAFVLLDECQNLTASQIKTIITRCGEGTKIVCSGNLAQIDSNYLSPVTSGLTYIVERFKNFEGSANIYLNGVVRSRLAEFAEENL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0G8</accession>
    <name>D0Z0G8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein HflK</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_003032</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">HflC and HflK could encode or regulate a protease.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">HflC and HflK may interact to form a multimeric complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the band 7/mec-2 family. HflK subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003032"/>
    <dbReference type="EnsemblBacteria" id="EEZ41999">
        <property type="protein sequence ID" value="EEZ41999"/>
        <property type="gene ID" value="VDA_003032"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0330">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03404">
        <property type="entry name" value="SPFH_HflK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010201">
        <property type="entry name" value="HflK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43327:SF2">
        <property type="entry name" value="PTHR43327:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="SSF117892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01933">
        <property type="entry name" value="hflK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="PHB" evidence="7">
        <location>
            <begin position="1"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="258"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="261"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ41999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="298" mass="33469" checksum="C2F78514874D338A" modified="2010-01-19" version="1">MVLRFGKFDQIVKPGLNWKPTFIDEVIPVNVQAIRSLRASGLMLTKDENVLKVEMDVQYRVDNAEKYLFSVTNADDSLRQATDSALRAVIGDSTMDEALTTGRQAIRADTQEAIDKIIAKYNMGIRVVDVNFQSARPPEAVKDAFDDAIAAREDEERYVREAEAYSNDILPKAIGRAERIKNEAEGYSERVVNGALGDVAQFDKLLPEYLKAKEVTRERLYLDTMERVYSNTSKVLIDTKSNGNLLYLPLDKMINQAPKAKAPETDSQSFSGIELEKVEPQTPVTPVPRTETGRQGRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0H0</accession>
    <name>D0Z0H0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RNA-binding protein Hfq</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003034</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003034"/>
    <dbReference type="EnsemblBacteria" id="EEZ42001">
        <property type="protein sequence ID" value="EEZ42001"/>
        <property type="gene ID" value="VDA_003034"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1923">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005001">
        <property type="entry name" value="Hfq"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34772">
        <property type="entry name" value="PTHR34772"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17209">
        <property type="entry name" value="Hfq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02383">
        <property type="entry name" value="Hfq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="66" mass="7442" checksum="9F552CB208EB26FC" modified="2010-01-19" version="1">MSIYLVNGIKLQGQIESFDQFVILLKNTVNQMVYKHAISTVVPARPVNHHHAATGTAERPQEKIEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0K9</accession>
    <name>D0Z0K9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Pantothenate:Na+ symporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_003073</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301759.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003073"/>
    <dbReference type="EnsemblBacteria" id="EEZ42040">
        <property type="protein sequence ID" value="EEZ42040"/>
        <property type="gene ID" value="VDA_003073"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4145">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="231452at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015233">
        <property type="term" value="F:pantothenate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015081">
        <property type="term" value="F:sodium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036376">
        <property type="term" value="P:sodium ion export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10327">
        <property type="entry name" value="SLC5sbd_PanF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011849">
        <property type="entry name" value="Na/pantothenate_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018212">
        <property type="entry name" value="Na/solute_symporter_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
        <property type="entry name" value="SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02119">
        <property type="entry name" value="panF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00813">
        <property type="entry name" value="sss"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00456">
        <property type="entry name" value="NA_SOLUT_SYMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0915">Sodium</keyword>
    <keyword evidence="7" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="4" id="KW-0769">Symport</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="123"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="162"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="189"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="240"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="273"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="310"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="373"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="396"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="427"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="452"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ42040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="485" mass="51657" checksum="857C5907D629FB64" modified="2010-01-19" version="1">MNSQILIPLVLYLAAVFGVAFMTRRHRGKGGFLNEYLVGGRSMGGFVLAMTLAATYASASSFIGGPGAAYKMGLGWVLLAMIQLPAAWLTLGVLGKKFAIEARLHNALTLNDILYARYKNRGVVILASIALLLAFFGTMVVQFVGGARLLQTVTGLSYNEGLMIFAVTVGLYTTIGGFRAVVMTDTIQGIMMIIGTIALLIGIVHAGGSMGELMTKLHHIDPALITPYGPNHFLTEPFMLSFWVLVCFGVIGLPHAAVRCMSYKDSKSLHKGMVISTAMVAFLMLGMHLAGALGRAIVPDVASPDQIMPTLMISVLPPLVAGIFLAGPMAAIMSTIDSQLIQASATLLKDLYINYINPSIAEGEEAQTKLPKLSLWVTGIFSGLVFVAAMNPPDMIIWLNLLAFGCLQAVFLWPLVLGLYWKKASAAGAYASMIVGLTTYISLSFIKPDMGGVHAIVPTLALGFIAFVAGSLLKPVAHTQPQQSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0L0</accession>
    <name>D0Z0L0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribosomal protein L11 methyltransferase</fullName>
            <shortName evidence="2">L11 Mtase</shortName>
            <ecNumber evidence="2">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">prmA</name>
        <name evidence="3" type="ORF">VDA_003074</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Methylates ribosomal protein L11.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>L-lysyl-[protein] + 3 S-adenosyl-L-methionine = 3 H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl-[protein] + 3 S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:54192"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:13826"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61961"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the methyltransferase superfamily. PrmA family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301762.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003074"/>
    <dbReference type="EnsemblBacteria" id="EEZ42041">
        <property type="protein sequence ID" value="EEZ42041"/>
        <property type="gene ID" value="VDA_003074"/>
    </dbReference>
    <dbReference type="GeneID" id="57340452"/>
    <dbReference type="eggNOG" id="COG2264">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1712450at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008276">
        <property type="term" value="F:protein methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00735">
        <property type="entry name" value="Methyltr_PrmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004498">
        <property type="entry name" value="Ribosomal_PrmA_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000401">
        <property type="entry name" value="RPL11_MTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00406">
        <property type="entry name" value="prmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="2">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ42041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="294" mass="32231" checksum="6F9797011BAE5B7E" modified="2010-01-19" version="1">MPWIQLKLNATAENAEAIGDMLMEETGALSVTFLDAQDTPVFEPLPGETRLWGDTDVIGLYDAEADMDFVQSMLKNSPLLADDFAYKIEQLEDKDWEREWMDNFHPMRFGRRLWICPSWREAPEPEAVNVLLDPGLAFGTGTHPTTSLCLEWLDGQDLTGKTVIDFGCGSGILAIAALKLGAAKVIGIDIDPQAILASRDNAERNGVADNLELYLPQDQPEGIQADVVVANILAGPLRELSPVIKSLVKDGGELAISGVLESQAEDVATYYSDELTLEPVVAREEWCRISGRKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0N8</accession>
    <name>D0Z0N8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 19">UDP-N-acetylenolpyruvoylglucosamine reductase</fullName>
            <ecNumber evidence="6 19">1.3.1.98</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18 19">UDP-N-acetylmuramate dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="primary">murB</name>
        <name evidence="21" type="ORF">VDA_003102</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 19">Cell wall formation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 19">
            <text>NADP(+) + UDP-N-acetyl-alpha-D-muramate = H(+) + NADPH + UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine</text>
            <dbReference type="Rhea" id="RHEA:12248"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:68483"/>
            <dbReference type="ChEBI" id="CHEBI:70757"/>
            <dbReference type="EC" id="1.3.1.98"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 19">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5 19">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4 19">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="19">Belongs to the MurB family.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.98" evidence="6 19"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003102"/>
    <dbReference type="EnsemblBacteria" id="EEZ42069">
        <property type="protein sequence ID" value="EEZ42069"/>
        <property type="gene ID" value="VDA_003102"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0812">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008762">
        <property type="term" value="F:UDP-N-acetylmuramate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.78.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00037">
        <property type="entry name" value="MurB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003170">
        <property type="entry name" value="MurB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011601">
        <property type="entry name" value="MurB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036635">
        <property type="entry name" value="MurB_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21071">
        <property type="entry name" value="PTHR21071"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02873">
        <property type="entry name" value="MurB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56194">
        <property type="entry name" value="SSF56194"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00179">
        <property type="entry name" value="murB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="16 19" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="9 19" id="KW-0132">Cell division</keyword>
    <keyword evidence="13 19" id="KW-0133">Cell shape</keyword>
    <keyword evidence="17 19" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="8 19" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11 19" id="KW-0274">FAD</keyword>
    <keyword evidence="10 19" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="12 19" id="KW-0521">NADP</keyword>
    <keyword evidence="15 19 21" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14 19" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="20">
        <location>
            <begin position="29"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="active site" evidence="19">
        <location>
            <position position="175"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="19">
        <location>
            <position position="245"/>
        </location>
    </feature>
    <feature type="active site" evidence="19">
        <location>
            <position position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00015188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00031026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="EEZ42069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="357" mass="39153" checksum="D43FF7BC4BDDCC6D" modified="2010-01-19" version="1">MPISIKVRSKNRMNQLHDTGLAPYHTFRIDAQASMIIEATSAEDFITLWQDPAYSQSPKLVVGQGSNLLFCEDYQGIVVLNRLKGIDVSEDAQAYHLHVAGGEDWHQLVKWTVENNMPGLENLALIPGCVGSSPIQNIGAYGKELKDLCEYVDVLNVLTGKISRLSAAECLFGYRDSIFKHQLKDDHIIIAVGLALSKDWQPQIGYGPLAQFDLKTVTAKEIFDTVCNVRLAKLPNPKELGNAGSFFKNPVISKQQAQQLLAEHSDMPSYPAGDEIKLAAGWLIDQCGLKGFTIGGAKVHEQQALVLVNTGSASAQDVMALAQHVVSCVYEQFGVELEHEVRFMAKSSETCLAKALQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0P8</accession>
    <name>D0Z0P8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 11">Soluble pyridine nucleotide transhydrogenase</fullName>
            <shortName evidence="11">STH</shortName>
            <ecNumber evidence="4 11">1.6.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 11">NAD(P)(+) transhydrogenase [B-specific]</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">sthA</name>
        <name evidence="15" type="ORF">VDA_003112</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 11">Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>NAD(+) + NADPH = NADH + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:11692"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.6.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11 12">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="11 12">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.6.1.1" evidence="4 11"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301894.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003112"/>
    <dbReference type="EnsemblBacteria" id="EEZ42079">
        <property type="protein sequence ID" value="EEZ42079"/>
        <property type="gene ID" value="VDA_003112"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1249">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="267896at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003957">
        <property type="term" value="F:NAD(P)+ transhydrogenase (B-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006739">
        <property type="term" value="P:NADP metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00247">
        <property type="entry name" value="SthA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022962">
        <property type="entry name" value="STH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="SSF55424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11 12" id="KW-0274">FAD</keyword>
    <keyword evidence="11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9 11 12" id="KW-0520">NAD</keyword>
    <keyword evidence="7 11" id="KW-0521">NADP</keyword>
    <keyword evidence="12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 11 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="14">
        <location>
            <begin position="12"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_dim" evidence="13">
        <location>
            <begin position="351"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="41"/>
            <end position="50"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="151"/>
            <end position="153"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="188"/>
            <end position="195"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="275"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="316"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEZ42079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="471" mass="51875" checksum="41CD812CE24F86ED" modified="2010-01-19" version="1">MIDNAVTPNHQFDVIVIGSGPGGEGAAMGLTKAGLNVAIIERESSVGGGCTHWGTIPSKSLRHAVSRIIEFNHNPLYCKNNMTLHSTFSQILGHAAEVVSKQTRMRQGFYDRNHCHLIYGQAQFIDSHTVQVTQADGRIERYQAQKFVIATGSRPYHPEHVDFSHPRIYDSDSILQLQHDPRHIIIYGAGVIGCEYASIFRGLGVKVDLINTRDRLLEFLDNEVSDSLSYHLTNHGAMIRNGELFETIDGHNDGVIVHLQSGKKMQADCILYANGRTGNTDTLNLEAIGLKANSRGQLNIDKTYQTEADHIYAVGDVIGYPSLASAAYDQGRFVAQIIAKGEAQNQLITDIPTGIYTIPEISSVGKTEQELTAEKIPYEVGRSQFKHLARAQIAGTEVGSLKILFHRETKAILGIHCFGERAAEIIHIGQAIMEQKGAGNTIEYFANTTFNYPTMAEAYRVAALNGLNRLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0S2</accession>
    <name>D0Z0S2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 9">DNA-binding transcriptional regulator NtrC</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Nitrogen regulation protein NR(I)</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ntrC</name>
        <name evidence="12" type="ORF">VDA_003136</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301967.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003136"/>
    <dbReference type="EnsemblBacteria" id="EEZ42103">
        <property type="protein sequence ID" value="EEZ42103"/>
        <property type="gene ID" value="VDA_003136"/>
    </dbReference>
    <dbReference type="GeneID" id="57340635"/>
    <dbReference type="eggNOG" id="COG2204">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="123059at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000156">
        <property type="term" value="F:phosphorelay response regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009399">
        <property type="term" value="P:nitrogen fixation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006808">
        <property type="term" value="P:regulation of nitrogen utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002197">
        <property type="entry name" value="HTH_Fis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025943">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025944">
        <property type="entry name" value="Sigma_54_int_dom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010114">
        <property type="entry name" value="Transcript_reg_NtrC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02954">
        <property type="entry name" value="HTH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00158">
        <property type="entry name" value="Sigma54_activat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01590">
        <property type="entry name" value="HTHFIS"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01818">
        <property type="entry name" value="ntrC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00676">
        <property type="entry name" value="SIGMA54_INTERACT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00688">
        <property type="entry name" value="SIGMA54_INTERACT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50045">
        <property type="entry name" value="SIGMA54_INTERACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0010">Activator</keyword>
    <keyword evidence="4 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-0535">Nitrogen fixation</keyword>
    <keyword evidence="3 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0678">Repressor</keyword>
    <keyword evidence="7 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 9" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="9" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="domain" description="Response regulatory" evidence="11">
        <location>
            <begin position="5"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="10">
        <location>
            <begin position="141"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="8">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ42103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="470" mass="52727" checksum="D61FB9678E087FB5" modified="2010-01-19" version="1">MSKGMVWVVDDDSSIRWVLERTLNAADLACETFADGDSVLQALERSLPDVLVSDIRMPGIDGFALLKSLQQHYPDLPVIIMTAHSDLDSAVNAYQEGAFEYLPKPFDIDEAITLVDRAVTHSQEQRRAKQPQTQEHTAPEIIGEAPAMQEVFRAIGRLSRSSISVLINGESGTGKELVAHALHRHSPRSEQPFVALNMAAIPKDLIESELFGHEKGAFTGANSVRQGRFEQANGGTLFLDEIGDMPLDIQTRLLRVLADGQFYRVGGHAPIKVDVRIIAATHQDLEVLVRDGDFRDDLFHRLNVIRIHLPALKDRRQDIAQLTRHFLQRAAKELGVELKTLHPDTLDLLTQMPWPGNVRQLENTCRWITVMASGNEVLPADLPPELLDIDKPSAALNEQHEWHRGLQLWAQDALRHGQENLLSEAQPIFERVLLETALEFTRGHKQDAAKLLGWGRNTLTRKIKELNIKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z115</accession>
    <name>D0Z115_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 13">ATP synthase epsilon chain</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12 13">ATP synthase F1 sector epsilon subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11 13">F-ATPase epsilon subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">atpC</name>
        <name evidence="17" type="ORF">VDA_003229</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 13">Produces ATP from ADP in the presence of a proton gradient across the membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 13 14">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cell membrane</location>
            <topology evidence="13">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13 14">Belongs to the ATPase epsilon chain family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302226.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003229"/>
    <dbReference type="EnsemblBacteria" id="EEZ42196">
        <property type="protein sequence ID" value="EEZ42196"/>
        <property type="gene ID" value="VDA_003229"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0355">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1696893at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12152">
        <property type="entry name" value="F1-ATPase_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00530">
        <property type="entry name" value="ATP_synth_epsil_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036794">
        <property type="entry name" value="ATP_F1_dsu/esu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001469">
        <property type="entry name" value="ATP_synth_F1_dsu/esu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020547">
        <property type="entry name" value="ATP_synth_F1_dsu/esu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020546">
        <property type="entry name" value="ATP_synth_F1_dsu/esu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036771">
        <property type="entry name" value="ATPsynth_dsu/esu_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13822">
        <property type="entry name" value="PTHR13822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00401">
        <property type="entry name" value="ATP-synt_DE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02823">
        <property type="entry name" value="ATP-synt_DE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46604">
        <property type="entry name" value="SSF46604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51344">
        <property type="entry name" value="SSF51344"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01216">
        <property type="entry name" value="ATP_synt_epsi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 13 14" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="13" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 13 14" id="KW-0139">CF(1)</keyword>
    <keyword evidence="13" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="17" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 13 14" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 13 14" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATP-synt_DE_N" evidence="16">
        <location>
            <begin position="6"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-synt_DE" evidence="15">
        <location>
            <begin position="90"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00014480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00031795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF02823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EEZ42196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="140" mass="15113" checksum="C024AEE64AC4DC7E" modified="2010-01-19" version="1">MAAITFHLDVVSAEKRLFSGRVENIQVTGSEGELGIHAGHTPLLTALIPGMIRITKQHGEEEVIYLSGGMLEVQPSTVTVLADTAIRGVDLDAAKAEEAKRQAMEHIHNPHGDIDYAQAASDLAKAIAQLRVIELTKRAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z146</accession>
    <name>D0Z146_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_003260</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IMPACT family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302319.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003260"/>
    <dbReference type="EnsemblBacteria" id="EEZ42227">
        <property type="protein sequence ID" value="EEZ42227"/>
        <property type="gene ID" value="VDA_003260"/>
    </dbReference>
    <dbReference type="GeneID" id="57340325"/>
    <dbReference type="eggNOG" id="COG1739">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1777855at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023582">
        <property type="entry name" value="Impact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015796">
        <property type="entry name" value="Impact_bac/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001498">
        <property type="entry name" value="Impact_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036956">
        <property type="entry name" value="Impact_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015269">
        <property type="entry name" value="UPF0029_Impact_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020569">
        <property type="entry name" value="UPF0029_Impact_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16301">
        <property type="entry name" value="PTHR16301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09186">
        <property type="entry name" value="DUF1949"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01205">
        <property type="entry name" value="UPF0029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00257">
        <property type="entry name" value="IMPACT_YIGZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00910">
        <property type="entry name" value="UPF0029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UPF0029" evidence="2">
        <location>
            <begin position="20"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1949" evidence="3">
        <location>
            <begin position="145"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ42227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="205" mass="22302" checksum="759FE6906FAC1EA6" modified="2010-01-19" version="1">MNSEPYWVPADAVVFEEEIKKSRFITYLAHTPNIEAAKAFVNHIKEKHHDARHNCWAFVAGRPTDSMKWGFSDDGEPSGTAGKPILAQLTGSNVGEITAVVTRYYGGIRLGTGGLVKAYGGGVQQALAQLITQEKVMTAIVTLCCDYNQVSLVESLLNEHSGVQLTADYQTQVSMALELDQREVSAFCAKLVNRSGGRIQPVTAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1K5</accession>
    <name>D0Z1K5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Arginine N-succinyltransferase</fullName>
            <ecNumber evidence="2">2.3.1.109</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003419</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.3.1.109" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302673.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003419"/>
    <dbReference type="EnsemblBacteria" id="EEZ42386">
        <property type="protein sequence ID" value="EEZ42386"/>
        <property type="gene ID" value="VDA_003419"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3138">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="972674at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008791">
        <property type="term" value="F:arginine N-succinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006527">
        <property type="term" value="P:arginine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007041">
        <property type="entry name" value="Arg_succinylTrfase_AstA/AruG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017650">
        <property type="entry name" value="Arginine_N-succinylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04958">
        <property type="entry name" value="AstA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03243">
        <property type="entry name" value="arg_catab_AOST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03244">
        <property type="entry name" value="arg_catab_AstA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="339" mass="37982" checksum="F6648B91B0E365F6" modified="2010-01-19" version="1">MLVVRPISVQDFEALKLCAQESGHGFTSLPVNDELLQRRIDNSVRSFNKRVTQPCSEGYLMVAEDSETGEIAGTTGIEAAIGLDIPFYSYHISKVVHSSRKLNVHNVVKVLTFGNNYTGNSELCTLFLRNEWRQGLNGRLLSKARFMLMAEYPERFSEVVFAEMRGVSDEHGSSPFWHWLKEHFFSIDFTQADYLTGIGKKGFIADLMPKLPIYVNLLSPEAQAVIGQVHPQTLPALKLLEKEGFCNRGYVDIFDAGPTVECDVRNIESVRHSQRAKVKIGEPSLRRQYLISNTSCKDFRAVAAPLSFDEESQTVVLSQQVADALRVTTGNSIRFVALT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1L0</accession>
    <name>D0Z1L0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Phosphoribulokinase</fullName>
            <ecNumber evidence="3 4">2.7.1.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_003424</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>ATP + D-ribulose 5-phosphate = ADP + D-ribulose 1,5-bisphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19365"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57870"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.19"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the phosphoribulokinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.19" evidence="3 4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302684.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003424"/>
    <dbReference type="EnsemblBacteria" id="EEZ42391">
        <property type="protein sequence ID" value="EEZ42391"/>
        <property type="gene ID" value="VDA_003424"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3954">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1793376at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008974">
        <property type="term" value="F:phosphoribulokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006082">
        <property type="entry name" value="PRK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006083">
        <property type="entry name" value="PRK/URK"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00485">
        <property type="entry name" value="PRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00478">
        <property type="entry name" value="PHRIBLKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00567">
        <property type="entry name" value="PHOSPHORIBULOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PRK" evidence="5">
        <location>
            <begin position="7"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ42391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="289" mass="32737" checksum="CEBAEA50C41C9EF6" modified="2010-01-19" version="1">MSAKHPIIAVTGSSGAGTTTTSEAFRKMFNMMNIKAAWLEGDSFHRFTRPEMDVEIRKAKEQGRHISYFGPQANDFPLLEQFFKQYGEDGSGEYRRYLHTFDEAVPYNQMPGTFTPKQQLAENTDLLFYEGLHGGVVDGDINVAQHVDLLIGMVPIVNLEWIQKIVRDTRDRGHSREAVTESIVRSMDDYLNYITPQFSRTHINFQRVPTVDTSNPISAKGIPTLDESFVVIRFRGLKNVDFPYLLAMIQGAFMSRHNTLVVPGGKMGFAMELIMRPLLQQLIEKGKIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1L1</accession>
    <name>D0Z1L1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alpha/beta fold family hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_003425</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302686.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003425"/>
    <dbReference type="ESTHER" id="lisda-d0z1l1">
        <property type="family name" value="abh_upf0017"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ42392">
        <property type="protein sequence ID" value="EEZ42392"/>
        <property type="gene ID" value="VDA_003425"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0429">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1119700at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012020">
        <property type="entry name" value="ABHD4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005211">
        <property type="entry name" value="Ab_hydro_YheT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="60"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ42392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="331" mass="37334" checksum="E3F20E97D1032DFB" modified="2010-01-19" version="1">MMTFTPAFGLANPHLQTLLPRFIHRNPQFTPEMERIETPDDDFLDIAWTESPHNITPDKPILVLFHGLEGSIRSPYAHGLLHVAKRYGWLGVMMHFRGCSHELNRQDRFYHSGETEDAHFFIQHLKRRFPNQPLLAVGISLGGNMLVNYLAQTGGNSGITAAQVVSAPLQLQACAGRIEQGFSKVYRSYLLGSLKKRLIGKIERGGNTMPVTKQQAEQITSLRQFDDLVTAPLHGFQNADDYYQQCSGMQYLAQVSTPLRLIHAKDDPFMTDEVIPTMSLPPHIEYTLYQHGGHVGFVTGSLLKPKMWLEKTIPVWFTEQLALNKQSSHGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1M7</accession>
    <name>D0Z1M7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">50S ribosomal protein L23</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplW</name>
        <name evidence="6" type="ORF">VDA_003441</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uL23 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302786.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003441"/>
    <dbReference type="EnsemblBacteria" id="EEZ42408">
        <property type="protein sequence ID" value="EEZ42408"/>
        <property type="gene ID" value="VDA_003441"/>
    </dbReference>
    <dbReference type="GeneID" id="57340102"/>
    <dbReference type="eggNOG" id="COG0089">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1978865at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01369_B">
        <property type="entry name" value="Ribosomal_L23_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012678">
        <property type="entry name" value="Ribosomal_L23/L15e_core_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013025">
        <property type="entry name" value="Ribosomal_L25/23"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11620">
        <property type="entry name" value="PTHR11620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00276">
        <property type="entry name" value="Ribosomal_L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54189">
        <property type="entry name" value="SSF54189"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ42408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="100" mass="11178" checksum="CFF672E5E6A56CF0" modified="2010-01-19" version="1">MITEERILKVLRAPHISEKATMAAENGNTIVFKVAMTATKKEIKAAVEKLFEVEVKSVNTLIAKGKTKRQGMRQGRRSDWKKAYVILKEGQDIDFAGSAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1P9</accession>
    <name>D0Z1P9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">30S ribosomal protein S4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rpsD</name>
        <name evidence="11" type="ORF">VDA_003463</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.</text>
    </comment>
    <comment type="function">
        <text evidence="7">With S5 and S12 plays an important role in translational accuracy.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the universal ribosomal protein uS4 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303520.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003463"/>
    <dbReference type="EnsemblBacteria" id="EEZ42430">
        <property type="protein sequence ID" value="EEZ42430"/>
        <property type="gene ID" value="VDA_003463"/>
    </dbReference>
    <dbReference type="GeneID" id="57340080"/>
    <dbReference type="eggNOG" id="COG0522">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1211060at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01306_B">
        <property type="entry name" value="Ribosomal_S4_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022801">
        <property type="entry name" value="Ribosomal_S4/S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001912">
        <property type="entry name" value="Ribosomal_S4/S9_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005709">
        <property type="entry name" value="Ribosomal_S4_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018079">
        <property type="entry name" value="Ribosomal_S4_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831">
        <property type="entry name" value="PTHR11831"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831:SF4">
        <property type="entry name" value="PTHR11831:SF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00163">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01390">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01017">
        <property type="entry name" value="rpsD_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00632">
        <property type="entry name" value="RIBOSOMAL_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 7 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_S4" evidence="10">
        <location>
            <begin position="3"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="S4" evidence="9">
        <location>
            <begin position="96"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ42430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="206" mass="23394" checksum="E099BE6B819D9325" modified="2010-01-19" version="1">MARYLGPKLKLSRREGTDLFLKSGVRAIDTKCKIDNAPGQHGARRGRLSDYGVQLREKQKVRRIYGVLEKQFRNYYQEAARLKGNTGENLLQLLEGRLDNVVYRMGFGATRAEARQLVSHKAILVNGQVVNVPSYKVAANDVVSIREKAKNQARIKAALEVATQRELPTWVEVDNKKMEGTFKRLPERSDLSADINEHLIVELYSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1T7</accession>
    <name>D0Z1T7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MSHA pilin protein MshD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003501</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303622.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003501"/>
    <dbReference type="EnsemblBacteria" id="EEZ42468">
        <property type="protein sequence ID" value="EEZ42468"/>
        <property type="gene ID" value="VDA_003501"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2165">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2063277at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="218" mass="23912" checksum="561EC6423B091838" modified="2010-01-19" version="1">MSTNLKSRGFTLIEGIITIVLLAIAMITLTSFLFPQLERSAIPMYQAKSAAIADAVFNEILSRQFDQNSDPLGDSVYRCGEAYPAAVSGAMTSNLCSKELGPDDELEKEQPQYSNDVDDFIGCWGVLSQCETHQGVEYRAIKDKENSLVGLIPGVSQSEYKHIAVIVNVNYVDNSHDQFKLVSAPKAAAELVPLKQISVTVDAGRYGSYQYKALRGNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1W7</accession>
    <name>D0Z1W7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cell division protein ZapE</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Z ring-associated protein ZapE</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">zapE</name>
        <name evidence="4" type="ORF">VDA_003531</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Reduces the stability of FtsZ polymers in the presence of ATP.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Interacts with FtsZ.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the AFG1 ATPase family. ZapE subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303712.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003531"/>
    <dbReference type="EnsemblBacteria" id="EEZ42498">
        <property type="protein sequence ID" value="EEZ42498"/>
        <property type="gene ID" value="VDA_003531"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1485">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="607330at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01919">
        <property type="entry name" value="ZapE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005654">
        <property type="entry name" value="ATPase_AFG1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030870">
        <property type="entry name" value="ZapE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12169">
        <property type="entry name" value="PTHR12169"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03969">
        <property type="entry name" value="AFG1_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="71"/>
            <end position="78"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ42498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="367" mass="42894" checksum="B4E9F23BC89653E7" modified="2010-01-19" version="1">MTPIEKYQLDLKQPDFVADPYQAAVIEQFDELYQNLLQQKPEQAKVSFWHQWFPPSQQAKSVPIKGLYLWGGVGRGKTYLMDLFFETLPTQRKQRIHFHRFMQYVHRQLGQLEQQVDPLKEVAKTLNKQIDVLCFDEFFVSDITDAMILANLFEALFAQGIILVATSNIPPHDLYRNGLQRARFLPTIALLEQHCKVIHLDSPTDYRLRQLEQAKLFYYPLTDVVAEQLQQAFISLSREPRIYGQPIHINNRAIATLGQASDVLYCQFSALCQTARSANDYIEIARLYHTVIVEGIPMMDDGQNDAMRRFIALVDEFYERRVKLLISSQISIEHMYQGTLLRFEFERCCSRLIEMQSHDYLAQQHRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z235</accession>
    <name>D0Z235_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">OMP_b-brl domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001862</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298833.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40830">
        <property type="protein sequence ID" value="EEZ40830"/>
        <property type="gene ID" value="VDA_001862"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031S7H">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1625058at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027385">
        <property type="entry name" value="OMP_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13505">
        <property type="entry name" value="OMP_b-brl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019989" description="OMP_b-brl domain-containing protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="OMP_b-brl" evidence="2">
        <location>
            <begin position="7"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="183" mass="19180" checksum="D662B6E9BD722609" modified="2010-01-19" version="1">MKKNALSLLVALAVIAPVAAQAAVQLPAGTQELGIQGNAKLGSGWDLNLNGSYGTFVKDNWEVGGTASVRAQDANDAISGKLGVFTEYNFVNSTNWVPYVGAATELAGLSYDNNNGASGDLGESGDSWALNIKLAAGVKYFINPNVALTAEANYNIATDDIDFSGDKAKDSLTNIVFGTRFYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z253</accession>
    <name>D0Z253_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Nucleoside permease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_001789</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298704.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40757">
        <property type="protein sequence ID" value="EEZ40757"/>
        <property type="gene ID" value="VDA_001789"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1972">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="437016at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005337">
        <property type="term" value="F:nucleoside transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008276">
        <property type="entry name" value="C_nuclsd_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018270">
        <property type="entry name" value="C_nuclsd_transpt_met_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011657">
        <property type="entry name" value="CNT_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002668">
        <property type="entry name" value="CNT_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011642">
        <property type="entry name" value="Gate_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10590">
        <property type="entry name" value="PTHR10590"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07670">
        <property type="entry name" value="Gate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07662">
        <property type="entry name" value="Nucleos_tra2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01773">
        <property type="entry name" value="Nucleos_tra2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00804">
        <property type="entry name" value="nupC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="86"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="166"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="251"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="285"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="346"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="386"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleos_tra2_N" evidence="7">
        <location>
            <begin position="8"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="Gate" evidence="9">
        <location>
            <begin position="92"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleos_tra2_C" evidence="8">
        <location>
            <begin position="194"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ40757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="407" mass="42891" checksum="0738095722899C7B" modified="2010-01-19" version="1">MHYLVSILGIITIFAVGYFFSENRRAVNWRTVLGAFTIQVIFAGFILYVPIGRDVLNAVSGVVSGIIDYGKVGSEFLFGELAKFKLGFVFAVNVLPTIVFFSALISVLYYLGVMGWIIRGIGGLLQKILGTTRTESMSATANIFVGSVEAPLVVRPFLAKMTHSELFAVMVGGLASVAGGTMVGYAGLGVQLKYLIAASFMSAPAGLMMAKLIVPQTDTVMTMDEEDDGEEDAPVNLVDAASRGALSGLQIAMAVGASLLAVISLVALINGGLGHLGNLIGIHDFSLQMIFGYLFAPVAWLIGVPWSEATTAASLIGTKIAVNEFVAFAELMKPETIAKLSEHSQAIVTFALCGFANLTSIAMLMGGLGGIVPQRRPDIARLGMKAIFAATLANLMSATLAGIFLPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z261</accession>
    <name>D0Z261_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">6-phosphogluconolactonase</fullName>
            <shortName evidence="7">6PGL</shortName>
            <ecNumber evidence="5 7">3.1.1.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pgl</name>
        <name evidence="9" type="ORF">VDA_001797</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12556"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57955"/>
            <dbReference type="ChEBI" id="CHEBI:58759"/>
            <dbReference type="EC" id="3.1.1.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 7">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 7">Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.31" evidence="5 7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001797"/>
    <dbReference type="EnsemblBacteria" id="EEZ40765">
        <property type="protein sequence ID" value="EEZ40765"/>
        <property type="gene ID" value="VDA_001797"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0363">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00409"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017057">
        <property type="term" value="F:6-phosphogluconolactonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01400">
        <property type="entry name" value="6PGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005900">
        <property type="entry name" value="6-phosphogluconolactonase_DevB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006148">
        <property type="entry name" value="Glc/Gal-6P_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039104">
        <property type="entry name" value="PGLS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11054">
        <property type="entry name" value="PTHR11054"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01182">
        <property type="entry name" value="Glucosamine_iso"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01198">
        <property type="entry name" value="pgl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucosamine_iso" evidence="8">
        <location>
            <begin position="10"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00020337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ40765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="237" mass="26563" checksum="E3F5F8808E49A355" modified="2010-01-19" version="1">MNYRVFETPDQVVNSLAETMREMSQQGRPIHISLSGGSTPKLLFKTLAQAPFATSINWQNLHFWWGDERCVEPTDPESNFGEANELLFKHVALPSENIHRILGEADPEQEVVRFANEMDKVIPHKHGLPAFDWILLGMGADGHTASLFPHQTDFNDQHLAVIATHPESGQKRISKTARLLENADRITYLVLGEGKAKILKEISEHSADELPYPAAKIQTQFGQTEWFLDSAAAQLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2D6</accession>
    <name>D0Z2D6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">FGE-sulfatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000587</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304782.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000587"/>
    <dbReference type="EnsemblBacteria" id="EEZ39567">
        <property type="protein sequence ID" value="EEZ39567"/>
        <property type="gene ID" value="VDA_000587"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1262">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005532">
        <property type="entry name" value="SUMF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042095">
        <property type="entry name" value="SUMF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03781">
        <property type="entry name" value="FGE-sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="SSF56436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019924" description="FGE-sulfatase domain-containing protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="FGE-sulfatase" evidence="3">
        <location>
            <begin position="65"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="289"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="342" mass="38831" checksum="911875AAAECD8FDC" modified="2010-01-19" version="1">MKVNSILLLIISANLVACNDSGNTVSSEIISKQEIARIDTNINKLYPDADSKLKQHILNVAVESLESMVFIKGGTFMMGDFKAPCSPLDLKRMDWTPEASCNTALSMTRTGANYQHKVTLSNYSLSNHETLALSFDVFRQAHNLPFLSEAFSQLKRTREDKKFMTLLKNTPMPTKSWQEAKDYCLWLGKLTNYPIDLPTEAQWEYAARNRGKNIYFATNNGYAQEIGSRYVNNDGSIHEYTKEQGNYGSFGDIKRWPPNPLGLYDMAGNSREWMNDWYSKDYYKVSPELNPQGPETGTEKVIRGWGGNMPLTTTRSHENPTDSKYISRRGFRCAVQSPTSIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2N5</accession>
    <name>D0Z2N5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000686</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305056.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000686"/>
    <dbReference type="EnsemblBacteria" id="EEZ39666">
        <property type="protein sequence ID" value="EEZ39666"/>
        <property type="gene ID" value="VDA_000686"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502Z7UT">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="853207at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022604">
        <property type="entry name" value="DUF2955"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016926">
        <property type="entry name" value="UCP029594"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11168">
        <property type="entry name" value="DUF2955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029594">
        <property type="entry name" value="UCP029594"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="196"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="222"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="247"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="296"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="341" mass="37616" checksum="00E013A16E2160D4" modified="2010-01-19" version="1">MKTMRIWFGCSMGLAVSMIFGWSYGFFAALLPMFVLVQADRWSTPLHVQLVLGIVWVTVQVSLLVGFFQPYPLLMTMAVAIMMLFKCVAMQHKSTYLFGFTGLLIGSILLNFASYNFFDIEEFSINLWMCGLATAPITALAYFLFPEPECATPQPVTVNNEVTKDEYGMVRQAAMGWTVAMVAYLVFQFGDLSDSLSAQASIFIVLTPMTLIGSMGAAKIRIIGTFLGCCAGMIIQLGLYTWIDNGLLFWMAYTIAAGFFCVWLAQGSIKSSIAFSAMSALSVPLTTSLVPEQKDAFFSILYRFSSIVVAVILTSIAIWATHIILHKLMPCVSHDTQESTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2Q2</accession>
    <name>D0Z2Q2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000703</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305105.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000703"/>
    <dbReference type="EnsemblBacteria" id="EEZ39683">
        <property type="protein sequence ID" value="EEZ39683"/>
        <property type="gene ID" value="VDA_000703"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3295">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1921658at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032307">
        <property type="entry name" value="PepSY_TM-like_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40115">
        <property type="entry name" value="PTHR40115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16357">
        <property type="entry name" value="PepSY_TM_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="187"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="208" mass="23519" checksum="C54AD26B7921D40C" modified="2010-01-19" version="1">MVLRSKGVQSWARRLHIYISMALLFVVLFFSITGITLNRPDWFVSNKPTVTEQVLSIPSEVVFVGDSFKPNQEGILRYLQQHADIAGHPSALDSYIESEDRELIEAEISFDYKGPGFSSSVFIEPLTQNVRIETTHYGLVAVLNDLHKGRNTGEIWKWFIDITALLMVVFVLTGVCLLLPKRKSLQLALRWTAFGSVISLAVFFLFVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-02-10" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2U9</accession>
    <name>D0Z2U9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ROK family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000750</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305245.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000750"/>
    <dbReference type="EnsemblBacteria" id="EEZ39730">
        <property type="protein sequence ID" value="EEZ39730"/>
        <property type="gene ID" value="VDA_000750"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1940">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1130699at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01125">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="303" mass="32314" checksum="61A7B8C1F72D7F44" modified="2010-01-19" version="1">MKNEQYYWGVDLGGTKIECAVIDRNTEECVVRERIATEGQFGYEHVLNRIKELIDLCKEKSGITPARIGFGTPGTLDPKLGVMKNCNSTSLNGKPLDKDLERILGCDVVLANDANCFALAEAHFGAAKRLKPDAEVVFGIIMGTGVGSGIVVNGKVINGCHGIGGEWGHNVIEPNGRDCYCGKKGCLETVMSGKGLEAYYQQLTGQNLPLPEIVAKARLGDEDGIKTLSRMIETFGLAVSQIINTIDPDVIVVGGGVGNIDELYEQGPKAILAHLFNPELNTLIVKPDLGDSAGVFGAAALVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2Y1</accession>
    <name>D0Z2Y1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative pullulanase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_000782</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 13 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305334.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000782"/>
    <dbReference type="EnsemblBacteria" id="EEZ39762">
        <property type="protein sequence ID" value="EEZ39762"/>
        <property type="gene ID" value="VDA_000782"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1523">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="99080at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051060">
        <property type="term" value="F:pullulanase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10315">
        <property type="entry name" value="CBM41_pullulanase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013784">
        <property type="entry name" value="Carb-bd-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005323">
        <property type="entry name" value="CBM41_pullulanase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004193">
        <property type="entry name" value="Glyco_hydro_13_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011839">
        <property type="entry name" value="Pullul_strch"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024561">
        <property type="entry name" value="Pullul_strch_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041111">
        <property type="entry name" value="Pullulanase_Ins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040671">
        <property type="entry name" value="Pullulanase_N2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045041">
        <property type="entry name" value="Pullulanase_PULA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43631">
        <property type="entry name" value="PTHR43631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02922">
        <property type="entry name" value="CBM_48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11852">
        <property type="entry name" value="DUF3372"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03714">
        <property type="entry name" value="PUD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18494">
        <property type="entry name" value="Pullulanase_Ins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17967">
        <property type="entry name" value="Pullulanase_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49452">
        <property type="entry name" value="SSF49452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02103">
        <property type="entry name" value="pullul_strch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PUD" evidence="3">
        <location>
            <begin position="77"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="Pullulanase_N2" evidence="5">
        <location>
            <begin position="201"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="CBM_48" evidence="2">
        <location>
            <begin position="321"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="domain" description="Pullulanase_Ins" evidence="6">
        <location>
            <begin position="504"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3372" evidence="4">
        <location>
            <begin position="931"/>
            <end position="1089"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF11852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF18494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="1103" mass="122142" checksum="F362E78979B5052D" modified="2010-01-19" version="1">MQFKLSPLSKILVSILTTVTMMGCNDSDSTVDSKDGYFDTTNPQNIIIKLPPTDGLTAKLNSAGEVSEPVKAKDGEAVVYYVTKPDQIRSNQFANYSLHIWNNDQCDRAADDMVNGAWDNTQNTPTGIDNLGPYWKINLKGGKSHCINFIVRDDKLSNVLGGDAQLDFNQISDRTASYLSGDTKAKDSREEAFVAMSGVANAEAHLIGAKTLVWNGAANADQVRLYVSLKGDIEPNKNYQYTNEYILLEPTQLTAQQESRFPYLAGQQAYAIPADVDMRSIVKAETVALAVDKQGTVLAGTKVQTAGILDQLFAPKAQSEPLGSMLVDNDVQFKVWAPTAQNVVLILFGDNKKELGRLQMDYNAQSGVWTSLTDKAKDGTYYRYLIDVFHPVSGQVEQYQVTDPYSLSLAMNSKYSQVVNLDDPNLKPDGWDELARPRDQSNPATFVIYEAHVRDFSAHDESTKPEYRGKFKAFTQSASVPVNHLKKLSKNGVTHLHLLPIFDIATIDEDTQQVANIEQPFSTLCAINPEVSQSTFSADCQSNLTIAEVLEREQSSDSAENPKVQELNRLISATDSFNWGYDPFHYTVPEGSYAINAEGKSRILEMREMVQAVKQDINMNVVMDVVYNHTNSAGPLSDTSVLDKIVPWYYNRLNPLTGAVENSTCCSNTAPEHAMMAKLIKDSLVVWSRDYKIDAFRFDLMGHHPLSQIQDALQAVQHVDPQTYFYGEGWNFGEVENDKLFVQATQPNLAGTGIGSFSDRLRDAVRGGGPFDGGNALRENQGFGNGAYVQPNEISTTSKESALHATDLVRLGMAGNLKAFKFENAQGAIIRGDQLDYNGQPAGYAKDPTEIQNYVSKHDNQTLWDNQQYKIPYDVSGEQRVRMQAVSLATAMLGQGVPFTHMGSELLRSKSMQRDSYDSGDWFNKVDFTLQDNNWNKGLPRKDKDGDNYSIIEQVIYGSGAHAQPSSKEMQQMVDYYLDLVHLRQSYPLITLGTGTEVIKRVAFHNTGVDRQPGLIIMSINNGQGLQDIDSTLDAIVIAINATPEIKTFDISFSGFELSNQYRSDLAKGAKVDGNLLTIPAWTPAVFVMPRTNERSQGLPVSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2Y4</accession>
    <name>D0Z2Y4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hypothetical hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000785</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305342.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39765">
        <property type="protein sequence ID" value="EEZ39765"/>
        <property type="gene ID" value="VDA_000785"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1473">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="796259at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017439">
        <property type="entry name" value="Amidohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11014">
        <property type="entry name" value="PTHR11014"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005962">
        <property type="entry name" value="Pept_M20D_amidohydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01891">
        <property type="entry name" value="amidohydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="2">
        <location>
            <begin position="178"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="379" mass="42275" checksum="88AD38816410519B" modified="2010-01-19" version="1">MSQEDFNPIRFRHHLHRYPELSLNEYKTASEITDQLLKFGLAPKTNIGGHGIIVEIVGEKSGPTTLFRADFDALPINEKPNHSHGSRHSGCMHACGHDGHTTSLLQLANILAHNPPASGTVILLFQPAEEIGLGAKNMLQDIRMQHIKPDAVFAYHNLPGYPLGEVVIKNDVFACASTGVNITFNGKTSHAAYPEHGISPATAVNRLMDYLDKITLSYQDNFNLITLVHVKIGNEGYGTSPGKAQVMATLRSDDETVLAQIQEELTKYAQVQAELHHLDLHIEWIEPFAATINNRQTTDSVRLAANTLHYSVNEIDHPLRWSEDVGEFLHQWPGTLFCIGSGEAHPQLHNPDYDFPDELIEISSQLFLQLIRQRHGLLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2Z4</accession>
    <name>D0Z2Z4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_000795</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305373.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000795"/>
    <dbReference type="EnsemblBacteria" id="EEZ39775">
        <property type="protein sequence ID" value="EEZ39775"/>
        <property type="gene ID" value="VDA_000795"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5000">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="692375at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031930">
        <property type="entry name" value="HK_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038428">
        <property type="entry name" value="HK_sensor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16750">
        <property type="entry name" value="HK_sensor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="150"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="9">
        <location>
            <begin position="175"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="8">
        <location>
            <begin position="238"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="258"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ39775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="456" mass="51949" checksum="CAD647C5DEA01AE5" modified="2010-01-19" version="1">MNRVLSRYQHSLAVKLFSYFAIILIVILGLQNLAEIALVRSMLQIPTHVQVDMRNLAHQAKSLVELGNKEVLTDWEEQQKYYLFVVDQQHNELSNRVMHPHFKFKLQFTRPLNTILDSQVSQPIISIPLPKVQATLMVQLPYQQHPAKNFSFYFGLIQIVIAVLILLLFSVLIARYLQRPLTTLQLASRKLADGDFSVRVTKEVGDNVLEFKALAQDLDIMASNIQLLAKKQKRLIRDVSHELKTPLARHDLALHLLRRRTQDQNKELLDQLEQQSDQMNTLVNEIIEFCRIDNAKYSTQLMPIQIDSICQIQFEESQRHLGLNQSLNLHLVDSFPMVMAESRLALRAIKNIIENAVKYAGSMAVIDVSTCLLIYQGRSYAAVVIEDNGVGIPSSQLKRIFDPFTRLEDSRDKQSGGYGLGLAIVKEAMTVMKGEVIAENRRSGGLRISLLFPIVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-06-02" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z327</accession>
    <name>D0Z327_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_000828</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305462.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000828"/>
    <dbReference type="EnsemblBacteria" id="EEZ39808">
        <property type="protein sequence ID" value="EEZ39808"/>
        <property type="gene ID" value="VDA_000828"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3221">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4191">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="322"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="5">
        <location>
            <begin position="375"/>
            <end position="586"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ39808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="588" mass="66657" checksum="8442883B87ECF544" modified="2010-01-19" version="1">MKINLLFSSKLLLFLTILSLVNSSKIYAQSLIKKKETITVGIFADRGKLEAHERWQKTIDLLNTQIPHYHFVLQPLLLEQLQQEISQQRLPFIIVNPSECVRIGRKYPLARLATLISPIGDGSTFSTGSAVWVKATSNITTISSLSGHRIGTASQQAFGGFMAFAREIAQNYALSHYFHQLIELGYPHESVVRALISGNIDAAILPVCLVESMISKKELKEDELRIIGQQNSANDMCMTSTPLYPNWSFAMTSTADRPLAKQIIKVLLNIPPHSLAAKSAQSLGWSVPESEVELDKLFSELGVHPLQKQWWHGAWQWLVNNYYIALIILILFTILPSQYIFLTVRYRRNSYKLRCAQESLQLVHRRALVDRLGSSLAHELNQPLAAIRLYAEGEISRRKQGRLDTDITLLLSKIQRQAIRIDEVVSRFRSLLQKKTIEKELFDINSIIMDAISLVEVYANQQQIHLYWQDINEKVYLLCDKAAIEQLLVNLLTNAIDATKLNKQEKVSISLLKNSDKIQLEIQDQGQGLPMPFEQLLTPFITTKKHGIGLGLAICKEVTESHQGELELLNIPSLGCLAIVRFPYVRRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z360</accession>
    <name>D0Z360_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative PmbA-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000861</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase U62 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305556.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000861"/>
    <dbReference type="EnsemblBacteria" id="EEZ39841">
        <property type="protein sequence ID" value="EEZ39841"/>
        <property type="gene ID" value="VDA_000861"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0312">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="958356at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045569">
        <property type="entry name" value="Metalloprtase-TldD/E_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002510">
        <property type="entry name" value="Metalloprtase-TldD/E_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035068">
        <property type="entry name" value="TldD/PmbA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036059">
        <property type="entry name" value="TldD/PmbA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01523">
        <property type="entry name" value="PmbA_TldD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19289">
        <property type="entry name" value="PmbA_TldD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111283">
        <property type="entry name" value="SSF111283"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PmbA_TldD" evidence="2">
        <location>
            <begin position="25"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="PmbA_TldD_C" evidence="3">
        <location>
            <begin position="228"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF19289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="447" mass="48198" checksum="6623FC7D97310665" modified="2010-01-19" version="1">MADQTQLQQAIDFVLNEAQKRGAEADVIASCSNNFSLKANNGELDEYKVTSGQVIGVRVVKDQRVATSYSESLEPQSLNIMVENALLNAQYSQIDEHQKISCLNSRITTDIAEIYQADDGNADQKIDLALSLERGVVAKPNAKGAPYNGFAESESQILIANTQGTQCYQKSRSTYCYAYTLYECDDKQSMYGAMSLGRKFSDLDPTHCIEHGYEMAKALADGTPIATKAYSVIFEHNALSSLFGAFGLCFSGVSAMKGINPWRDALHSQVASTQLTLTDKVYMPGGFAIGSFDSEGFASQDTVLIGNGELQSMLHNSHTASYFGISNTAHASRSAKGGLSVGGNHTVISTGTATESDVTAGEYLELVDLQGVHSGADAVSGDFSFGASGFLCRDGQRLQPVRGITVAGNFYQMIKEIDVMSNVLHADDEHDFYAPTIRFSRLNIAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3B2</accession>
    <name>D0Z3B2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000913</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305704.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000913"/>
    <dbReference type="EnsemblBacteria" id="EEZ39893">
        <property type="protein sequence ID" value="EEZ39893"/>
        <property type="gene ID" value="VDA_000913"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502ZP3A">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="195556at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="533" mass="58947" checksum="E538975CF55FE4D4" modified="2010-01-19" version="1">MLVNIPLMKGEIPRLKPHLLPNESSVKAIDCQFENGIISPIKSDKWVQNLSILVKTLFKYNDEHWFIWPKKVEAIHNPMAQDKWQRVYFTGDGKPQVTAQDIAIGPVSPAASYELGVPAPATKPVIEQIDDSTGEEPSQGEAALFDDETRFYIQTYVTRFGEEGMPSLPSSEILIEKPGSTVHLLLARPEQNKNNITRTRLYRSVTSNNSAEYMLVAELPISQERYLDAVKTINGPILETWDFAVPDANMRGLCQMANGICAGFAGNEVMFSEAYLPYAWPKGYRGTTEHPIVGIAAIGTSLVVLTKGYPYLFSGVTPSAINGTKIASEQACVSAESIVVVNGAVIYASSDGLVAIGSDGAMTITDQLITRSQWQKKTPQTIRAWAAEGLYIGISKTGSFIFDPVSQDFRELSNRWDCAYSDLERDQLFVVKDKQLYIWQGGENDLPLIWRSKVFKLPTDSLMSCARVISNDISKLSIKIIADGKDIYSLSTGELTDRSFRLPAVRATNWQIEVSGNAEVERLAIASSLQELT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3C0</accession>
    <name>D0Z3C0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000921</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000921"/>
    <dbReference type="EnsemblBacteria" id="EEZ39901">
        <property type="protein sequence ID" value="EEZ39901"/>
        <property type="gene ID" value="VDA_000921"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3170">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="587"/>
            <end position="610"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="638" mass="72665" checksum="F7BA14EF1843A2D3" modified="2010-01-19" version="1">MMIQTKVDQKKLLQIMADIDAQPDWRSLANKACSYYDGDQLAPEVISILKERNQPRTTHNLIKPTINGVLGMEAKTRTDLLVTADDPDDEMEQLAEAINAEFSDVCRLARLDKARSDAYASQIKSGIGFVEVFRNPDLFGSKYKIKNVPRDEIFWDWLSTECDWSDARWVMRRRWIDTDELISLIPGKAEIIKNAANCWHNFVDVDHIDGMDSNLLSAYNEYQSWSREDSEWLSGNRQRIRLQIIYYRKIERKPVIELSDGRIIEYQSQNIAHVTAVAMGKVKLQMAQASTIIESWYAGPHHLGDKLCDAPYGMFPIVPFWGYRKDSSGEPYGLVADAIPAQDEVNFRRIRLTWLLQAKRVLMDEDATNMSDRAVQEEVERPDGLIKLNPDRRNQKSMSEVFQVQQDFNIASQQFSVMQESMKLIQDAMGVYSSFLGQDGGQKSGVAIANLVEQGATTLAEINDNYRFACQLVGELILGYILNDMKGRRNYKLIINRDDKSKRKPIVINEETEQGLNNDVTRLRAHIALAPIQQTAAYKSQLAERMMQITSQLPPEVQSTVIDLVLELSDVPNKSEFMERVRKALGVGKDPEDMTPEEQKAALEQQQQEQAQQKLMMRELIARVSKIEAEATASSLIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3I2</accession>
    <name>D0Z3I2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">[NiFe] hydrogenase metallocenter assembly protein HypE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000983</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HypE family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305906.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000983"/>
    <dbReference type="EnsemblBacteria" id="EEZ39963">
        <property type="protein sequence ID" value="EEZ39963"/>
        <property type="gene ID" value="VDA_000983"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1016556at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02197">
        <property type="entry name" value="HypE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.650.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011854">
        <property type="entry name" value="HypE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010918">
        <property type="entry name" value="PurM-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036676">
        <property type="entry name" value="PurM-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016188">
        <property type="entry name" value="PurM-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036921">
        <property type="entry name" value="PurM-like_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30303">
        <property type="entry name" value="PTHR30303"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00586">
        <property type="entry name" value="AIRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02769">
        <property type="entry name" value="AIRS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005644">
        <property type="entry name" value="Hdrgns_mtr_HypE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55326">
        <property type="entry name" value="SSF55326"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56042">
        <property type="entry name" value="SSF56042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02124">
        <property type="entry name" value="hypE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AIRS" evidence="2">
        <location>
            <begin position="36"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="AIRS_C" evidence="3">
        <location>
            <begin position="159"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="330" mass="35594" checksum="5B923A214A4CDC5F" modified="2010-01-19" version="1">MKQVQLSHGGGGVEMNKLINQLFFRYLGNEILLRNEDAAVLECSGPIAMTTDSFTVSPLFFEGGNIGKLAIAGTVNDLAMMGAEPQYLTSSFIIEEGFSLDDLEVIVKSMADELKVSGAKIVCGDTKVVPKGSADGVYINTTGVGHIRQRGISSHNVAEGDTLLVSRDVGCHGACVLTARESLKLASPIASDCATLWPTVKALLDQGIKIHSLRDATRGGIAAVFNEWCQTSEVQITLDEQQIPVNDSVRGICELFGFEPYDLANEGTFILAVPHQDAERALDVLQQFNPQAAIVGTACRSEQHRVVLNSPWGSRRYLDFPAGELLPRIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3J9</accession>
    <name>D0Z3J9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305952.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001000"/>
    <dbReference type="EnsemblBacteria" id="EEZ39980">
        <property type="protein sequence ID" value="EEZ39980"/>
        <property type="gene ID" value="VDA_001000"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003020044" evidence="1">
        <location>
            <begin position="24"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="184" mass="20511" checksum="9EAC941A19F508E3" modified="2010-01-19" version="1">MYHKGSMLFGICILSVIPQVSFANSNMYTLTESSQGISELFENQSSNAMSGQDELKTFKLKEITTHEGNVEYRFIPVVVSKPSHKWIEAEGVYSIDSSDTQKNCSELDSFGATWRAPTATEIQAALSYDTDLRAIIEKLPGDDIIKGYVDIGEWYYIRSNHTGGAIDKNMGDGDPRPTICYLDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3P3</accession>
    <name>D0Z3P3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">L-proline Glycine Betaine ABC transport system permease protein proW</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_001044</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306067.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001044"/>
    <dbReference type="EnsemblBacteria" id="EEZ40024">
        <property type="protein sequence ID" value="EEZ40024"/>
        <property type="gene ID" value="VDA_001044"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4176">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="485527at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="82"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="105"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="149"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="228"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="259"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="102"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="296" mass="32341" checksum="9292B2964682A629" modified="2010-01-19" version="1">MSDSWLTEIPQLDRAQLLEIRKTLDGAYRSFSREYGDTIEGFFDPLLSFLVWFENLLLDSPWWLVIAVLASLAYVASRSWKLTLGVIVSFVLIGVFGMWDNTMRTMSIILVSTLVAIGVGIPIGIAMARSDRVQNGVTPMLDVMQTMPAFVYLIPVVMLLGIGKIPGVIAVVIYAIPPVIRLTNLGIRLVDKEVLEAATAYGASPMQRLFGVQLPLAMPNIMAGINQTIMMALAMVVIASMIGVKGLGQPVLKSITNQYFTLGLLNGLAIVALAIIFDRISQSYAKRTQQHLGGSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3Q7</accession>
    <name>D0Z3Q7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">2-dehydro-3-deoxy-phosphogluconate aldolase</fullName>
            <ecNumber evidence="3">4.1.2.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001058</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2-dehydro-3-deoxy-6-phospho-D-gluconate = D-glyceraldehyde 3-phosphate + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:17089"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:57569"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.1.2.14"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the KHG/KDPG aldolase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.14" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001058"/>
    <dbReference type="EnsemblBacteria" id="EEZ40038">
        <property type="protein sequence ID" value="EEZ40038"/>
        <property type="gene ID" value="VDA_001058"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0800">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008675">
        <property type="term" value="F:2-dehydro-3-deoxy-phosphogluconate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00452">
        <property type="entry name" value="KDPG_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000887">
        <property type="entry name" value="Aldlse_KDPG_KHG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031337">
        <property type="entry name" value="KDPG/KHG_AS_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031338">
        <property type="entry name" value="KDPG/KHG_AS_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30246">
        <property type="entry name" value="PTHR30246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01081">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01182">
        <property type="entry name" value="eda"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00159">
        <property type="entry name" value="ALDOLASE_KDPG_KHG_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00160">
        <property type="entry name" value="ALDOLASE_KDPG_KHG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="210" mass="22554" checksum="6D57EDF76739E297" modified="2010-01-19" version="1">MTKEWLMKLRDLKVMPVIQIDNADDAVPLAKVLIDNGLPAAEITFRTAAAAESIRRIRAEFPDIVLCAGTVLTKEQADEATAAGADFVISPGFNPTTVKYCIENNIKMIPGVNNPSLVEQALELGVTALKFFPAEASGGINMLKSLTGPYSQIQLMPTGGVNPKNLLDYLAISQVIACGGTWIAPTAAINAHDWDLIAHNVREAVKLTQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3U1</accession>
    <name>D0Z3U1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Surface protein Lk90-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001092</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306203.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001092"/>
    <dbReference type="EnsemblBacteria" id="EEZ40072">
        <property type="protein sequence ID" value="EEZ40072"/>
        <property type="gene ID" value="VDA_001092"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502ZXPB">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1405772at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="445" mass="48816" checksum="BF03BA245FCB05B1" modified="2010-01-19" version="1">MNKINIIAVACIISSLLSGCDGDNDNSSVVKSADKPIITDIFDKIEYNNDEIYHIDLSHSVVDPAGFPLYLESINSSSEDCSIISFDKDSLSLELTTNGKTACNLDYTVRNIPISSDIQSSSGNGNQYLLISDSNDDIDLLAISLTTTINTDPIEIDLKKELADRYPDGFVILSASNNGEGHIDDIDKESSIITFSSSIVGRNRIYYSLTDGKTITPGFIDIAVSDIGIEQPEADNFIAEAVVTPGEENNINIQGHFDDKGQKLQLADVSAFNADVSIINQYEFSFVSEQPGIHYVTYYVTNELGGLAVGIIQVNVGGAPYQDITIDIDGIDTTFVAPKEINSLSEDEKKSVVAKYKETGEFGPKGVIMPLFDVTGSVQVCNKMRSFVPSIDELKKLYNNAEENLFEQYYWPITKKYITSEGFLFDFKTGEVTYSDGIGYLTCLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3X3</accession>
    <name>D0Z3X3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Choloylglycine hydrolase</fullName>
            <ecNumber evidence="5">3.5.1.24</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001126</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C59 family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.24" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306285.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001126"/>
    <dbReference type="MEROPS" id="C59.001"/>
    <dbReference type="EnsemblBacteria" id="EEZ40104">
        <property type="protein sequence ID" value="EEZ40104"/>
        <property type="gene ID" value="VDA_001126"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3049">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="636485at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045302">
        <property type="term" value="F:choloylglycine hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029132">
        <property type="entry name" value="CBAH/NAAA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02275">
        <property type="entry name" value="CBAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018893" evidence="3">
        <location>
            <begin position="21"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="CBAH" evidence="4">
        <location>
            <begin position="21"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="363" mass="39995" checksum="D0C7E83140EC911F" modified="2010-01-19" version="1">MKLKLLSALLASVVAYSANACTGISLSSTNHDYVQARTIEWGESDLNSKLVVSPREHSYTSILPDQKKGLTWQSKYGFAGISVSDDRFIAEGVNEEGLTAGLFYFKNYGSLAKYDPNSVANNITDMDFVRWMLSQFKTVAEVEQALNQIKIVPVYMDAKGNPSPTAHWRVSDKQGNSIVIEIMDHGQIHIHKNTAKVLTNAPDYNWQVTNLNNYINLHPGVSQAQQINGVNAFSFGVGSGALGLPGDITPPSRFVRAAFYVNSAPVMKTGDEAVSQAFHILNNFDIPIGSEFNAKEYIPADLPSATQWTSVIDQTRGLLFYKTMRDSTIKKVDLSKLSFTGKKEEVRPLDNGKFSVEDVTPSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z443</accession>
    <name>D0Z443_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Pantothenate:Na+ symporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_000299</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000299"/>
    <dbReference type="EnsemblBacteria" id="EEZ39281">
        <property type="protein sequence ID" value="EEZ39281"/>
        <property type="gene ID" value="VDA_000299"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4145">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
        <property type="entry name" value="SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="62"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="112"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="143"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="177"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="227"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="262"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="303"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="357"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="382"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="411"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="436"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ39281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="470" mass="50636" checksum="A2EEA8884F95083D" modified="2010-01-19" version="1">MVGLATYSNKVMHKGNGEGGFLLASNCLGPFIGASTIVATAFSGWGFMGSPGVAYKYGAIELLGNFFFAPAIVLAVLFCARFLHHKAQTMGTLTIPEYIAHSHSGPDSIKRVTQAFAAIITIVLLLVFLVGQIKALGLLAGQWLGIDAITASLMMVGVIILYTSVGGLAAVAFTDTFMVIGMCASALIVVVTIFADISPTDFIDQLNQIDPQLLAPDNSGPYGESQWHVLMVLPYAFIYSATLPYMSVRFMAFAKTTKLHHVAAYITPMACLLSLVPMVGLYMRVKMPELDNPDSAMPMFLTHYLSPTLSAIVTLFILFAMKSTANSVLHAISGAVSHDLRQALWPQCKLNKKQLLMFNRVSVLLLGLLGFVIMLFTPPLMLSMLAILGSGTLMAALVAPTLLAHWFPGNIYAALSSLVVGFLSGTAMFVHWDLGWVEAPLYASFLACCSYVIIGKCFQNQLITHTSSLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4A5</accession>
    <name>D0Z4A5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Endoribonuclease L-PSP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000361</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304150.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000361"/>
    <dbReference type="EnsemblBacteria" id="EEZ39343">
        <property type="protein sequence ID" value="EEZ39343"/>
        <property type="gene ID" value="VDA_000361"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0251">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="376009at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11803">
        <property type="entry name" value="PTHR11803"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="SSF55298"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="421" mass="45219" checksum="5864C471AC856889" modified="2010-01-19" version="1">MSGSIIKVSRNTQTAPLAMTATQTVAFSHYNNISAQLGLDLVTGEMVKGGVKEQAAQCLANIKAVVESIDHVMDDVVKINVFVKDMADIDAINEVYAGFFNDYYPTRTVVGVAALPLTGALVQMDALISNGEGTAPQAPCDLIKLSRNTERAPLDALSTQTVAFSHYNNLSAQLPVDPQTGVMVAGGIKEQATQCLRNIKNVLESIDVPFDDIVNVRIYLKDLADIDAVNEVYMTFFPDSAIARAVAYMPARTVISAASLPMNALVQMDVVVSHGDGTPPQEIEDRHGIVIRTNNTDLAPINPLYTQTVAFSHYNHIAAQLPIDAKSNKIVTGGAHDQARQCLENIKAIVESIDHVMDDIVKINIQVKDMADLAAIDDVYSTFFTGELPARTVVGVNDIAQGAMVQIDAVVSNGEGTPPQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4H3</accession>
    <name>D0Z4H3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000431</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000431"/>
    <dbReference type="EnsemblBacteria" id="EEZ39411">
        <property type="protein sequence ID" value="EEZ39411"/>
        <property type="gene ID" value="VDA_000431"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1361">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1404">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2931">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025592">
        <property type="entry name" value="DUF4347"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045474">
        <property type="entry name" value="GEVED"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14252">
        <property type="entry name" value="DUF4347"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20009">
        <property type="entry name" value="GEVED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4347" evidence="1">
        <location>
            <begin position="57"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="GEVED" evidence="2">
        <location>
            <begin position="920"/>
            <end position="969"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="971" mass="104309" checksum="659BBEBA140ABCBE" modified="2010-01-19" version="1">MRIHTSALLIILGFILFADLFTERVISERVIVVDQQLMSDEFFHNELNVHYSISSISDFIIYLNTHSKFDSVDYFSHGRSGEIRFGRDTITLNNIYSYQTEIQQLGKVLGVDSTLNLLACDLGKTEDGKKLLAIFAQLAGITVYASDDKTGSLELNGDWDLELVYGEPDEKFIPLDLYVDYSGILADTDGDGVDDAIDIDDDNDGILDTDEIVCEVDVPLDLSGITAGSPDESNTPLLTTMFDGVLSGTSTGSPAGTNTGQIRLSVAGGVGEQMVYTITFADPVKLILSQSDSFSWFDSSDEWSVSVTGAILSVYNPAITHARLGGTSPELQNIVGDNTSSVSFQPLATGGHIPAVDSQWSITSSDFVSSVTLTYSNSTAPTNSSPIKLRTTCVSDDVDNDGIYNHIDLDADGDGIPDNIEAQTTIGYVASNTDSIATYTANNGINSAYLGGLTPVNTDGTDEPDFRDLNSDNQGANDTTEAGLTLLGLVGVNGLHGNLESSDDYLDANGIFDNTQTDNFPDPDNDVTGYGDIEFRDVVVSCDISGLAGATTKTATEFVTISGTPLRIDHIASGGNGVGYNGGRQSYQYTSYSCGGTFPFMHVNDGSNGEYCNYKDYLVSNVTGSGSTVDPYVIWSSRYWDRDGNNLFDNSDIRIVTKITYTNGDEFFDQQYCVDSADGLNSSSIGLAQGFDTYLNGGDQGAAFTIPYNTANYQPASPPYSLVGVTKNYTINDQFMGYLELDRSWDRYFSGQYSTMIGTNLNSSPFLLDNTLDTNTGTDNGIGVQWGLGVINDASIHSVRLLFSSLGGAIFQANDYDLGDAPDTSTGTASGDYQTLYDNGGAGHAFNDTDGDSQNDIVLGLLWDNDDGNLHNIAATADDLDSSDDEDGVIWTDSFIRGGSADTSITITKDPESTLVGLRLYAWADWNQDGDWDDANEQAIIDTSANTGTQNYTITIPAAASLGNTYLRVRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4H9</accession>
    <name>D0Z4H9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000437</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304363.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000437"/>
    <dbReference type="EnsemblBacteria" id="EEZ39417">
        <property type="protein sequence ID" value="EEZ39417"/>
        <property type="gene ID" value="VDA_000437"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1470">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="973956at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001434">
        <property type="entry name" value="DUF11"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01451">
        <property type="entry name" value="B_ant_repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018914" evidence="1">
        <location>
            <begin position="25"/>
            <end position="918"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="918" mass="94726" checksum="5C8B9CE64C0C6C5F" modified="2010-01-19" version="1">MNVFKGIAKVGITAVASISFAAMALTESGTVIKNQAGATYRDSANILRSTTSNLVETLVQPVAALTLINDQSKLGAPGRTVTFNHVLTNTGNSTDSFALDMVLPASVISSATIYPDTNNDGVADPGSTPIASGDVVGPLAPGESFEFVIVADIDPAATINSSNALTITATSQAVVVDGVAVANGGVSAQTNTDTVTATNLPIVEITKALSSSEGASPSGPYTVTFTYTNVGLTDMDPLQTNGVILNDVLPEGMRFNGAVSWSISGTTITASGTTTGGSETSGDQDLAFTTCIAPDASCPNNDEIQFVMDGLASDESATISFEVNIDSGLSATTLYNQGTYGFDEDNSGTVDVGEQDSTNTNRVPFLITSNYAVIANNGGCDVGTDNNCDGSDDTNHEIVDIASASQGARVSFTNYIWNTGNDEDIFNISIESSTFPSGTSFFLYKSDGVTPLIDTDNDSNPDTGVIPAAGETCPSYLVTDGNLCGYKVVLVATLPASALGGPYQITKRATSSSDTSKTNTVIDRLGTITASTVDLTNNFRAETSLTVEDSCDAADDNCGIGAGPEATPVTTNTTAPGTTTRFTLYVTNTSGAADSYELQYSSTNFAENTMPADWSVVFKNAAGEVITNIPVLGPDDAMLVYADVTVPENATTATQDVYFKVVSPTTGASDIKRDAVTIDNSSQCLAFGPPNANGVTYAGGSIVYKHILNNTSNDAYTNIALTVTNSDSDFSAVIYEDTNGDDVLTGADNSITSIASLAGGAQKVLFVKVLAPANASQGQDNITTVETTVACGTLQIIDTTTIANTNMKVTKEQTPDLDCNGTSDTGNFVTTNFAVAPGECIIYRLTTENIAIEDAHNVTLTDATPAYTTFNVTGGIPSITEGTINTVINGTTGSIIGTVGTVAPGESETLIFGIRIDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4K2</accession>
    <name>D0Z4K2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000460</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304425.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39440">
        <property type="protein sequence ID" value="EEZ39440"/>
        <property type="gene ID" value="VDA_000460"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1811181at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="172" mass="20577" checksum="8665AEDCDC650FE9" modified="2010-01-19" version="1">MTLEQHFLAIYQDNWSFSAKEQEFIQSFIENQQLRFQDICQKKDKDSFQLLLGLMTHLWQQEQDNLEHHRDAHNAMDEMLTHTIGKLHKQKFTNQDRLHFELLSQLYLAVQGATGIDISYANEQAEIAAETLNSEHLHQSRSSLLKHYYIGREYYQSQKPSWWRCLLKRLTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4K8</accession>
    <name>D0Z4K8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Branched-chain amino acid transport system carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_000466</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the transport system for branched-chain amino acids.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell inner membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the branched chain amino acid transporter family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000466"/>
    <dbReference type="EnsemblBacteria" id="EEZ39446">
        <property type="protein sequence ID" value="EEZ39446"/>
        <property type="gene ID" value="VDA_000466"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1114">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015658">
        <property type="term" value="F:branched-chain amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004685">
        <property type="entry name" value="Brnchd-chn_aa_trnsp_Livcs"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30588">
        <property type="entry name" value="PTHR30588"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05525">
        <property type="entry name" value="Branch_AA_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00796">
        <property type="entry name" value="livcs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="80"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="114"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="144"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="185"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="225"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="271"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="312"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="337"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="368"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="407"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ39446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="437" mass="46384" checksum="718DACB5D39CBEA0" modified="2010-01-19" version="1">MKRTELAAIGFMTFALFLGAGNLIFPPLMAQQAGENWLIAIGGFLLTAVGLPALTLLVLGRLSSADKLTARLPKWLDRTFWFLVLTTLGPAFVLPRAVTVAYEMGIKPFVGSNDGLMIFSIIFCALTLLLAVKPGKLVDYIGKVMTPALILMLAVLVIAALVNPLGGTLPATEIYQKAPVVNGLIQGYMTLDAIAAVAFGWVIIQTIRSKGVECNKALSGYIFKVVAIYATLMSLCYLAMGYLGATSSTIAANATNGGEILTRYAAGEFGALGQFLLAAITLMACLTTTIGLTNANAEYYQNTYGIKFRHSAMVITLLTALVSNVGLETIIEVSLPAILILCPIAIALIIATIALGNNQAKSVSLEQTAIVIVAALFGSLDALNILGKLSEGTKEVCQQWIPLFNSHVSWLAPVFIVIIAVKAVTLVKRRTEVAPAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4M1</accession>
    <name>D0Z4M1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Pyrrolidone-carboxylate peptidase</fullName>
            <ecNumber evidence="9">3.4.19.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">5-oxoprolyl-peptidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Pyroglutamyl-peptidase I</fullName>
            <shortName evidence="9">PGP-I</shortName>
            <shortName evidence="9">Pyrase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">pcp</name>
        <name evidence="12" type="ORF">VDA_000479</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 9">Removes 5-oxoproline from various penultimate amino acid residues except L-proline.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9 10">
            <text>Release of an N-terminal pyroglutamyl group from a polypeptide, the second amino acid generally not being Pro.</text>
            <dbReference type="EC" id="3.4.19.3"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 9">Belongs to the peptidase C15 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.3" evidence="9"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304478.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000479"/>
    <dbReference type="MEROPS" id="C15.001"/>
    <dbReference type="EnsemblBacteria" id="EEZ39459">
        <property type="protein sequence ID" value="EEZ39459"/>
        <property type="gene ID" value="VDA_000479"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2039">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1927224at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016920">
        <property type="term" value="F:pyroglutamyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00501">
        <property type="entry name" value="Peptidase_C15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00417">
        <property type="entry name" value="Pyrrolid_peptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000816">
        <property type="entry name" value="Peptidase_C15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016125">
        <property type="entry name" value="Peptidase_C15-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036440">
        <property type="entry name" value="Peptidase_C15-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029762">
        <property type="entry name" value="PGP-I_bact-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033694">
        <property type="entry name" value="PGPEP1_Cys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033693">
        <property type="entry name" value="PGPEP1_Glu_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23402">
        <property type="entry name" value="PTHR23402"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01470">
        <property type="entry name" value="Peptidase_C15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015592">
        <property type="entry name" value="Prld-crbxl_pptds"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00706">
        <property type="entry name" value="PYROGLUPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53182">
        <property type="entry name" value="SSF53182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00504">
        <property type="entry name" value="pyro_pdase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01334">
        <property type="entry name" value="PYRASE_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01333">
        <property type="entry name" value="PYRASE_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 9 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 9" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0788">Thiol protease</keyword>
    <feature type="active site" evidence="9 10">
        <location>
            <position position="80"/>
        </location>
    </feature>
    <feature type="active site" evidence="9 11">
        <location>
            <position position="143"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ39459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="212" mass="22697" checksum="9E8919F6E5C9DF1B" modified="2010-01-19" version="1">MKKVLITGFEPFGGASINPALEAVKQLEAISFTNATVVTCQVPVARFKAIDTVISAIEYHQPDIVITIGQAGGRAAITPERIAINIDDFRITDNDGNQPTDQPVIEQGPDAYFSTLPIKAITQALQQQGIPCQVSNTAGTFVCNHLFYGIQHYLRDSNTKHGFIHIPLLPEQAPAGDQPSMSLDTIVLGLKIAIEATVSNEQDISVGAGTIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4N9</accession>
    <name>D0Z4N9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein QmcA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000497</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the band 7/mec-2 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000497"/>
    <dbReference type="EnsemblBacteria" id="EEZ39477">
        <property type="protein sequence ID" value="EEZ39477"/>
        <property type="gene ID" value="VDA_000497"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0330">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018080">
        <property type="entry name" value="Band_7/stomatin-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001972">
        <property type="entry name" value="Stomatin_HflK_HflKC_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00721">
        <property type="entry name" value="STOMATIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="SSF117892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01270">
        <property type="entry name" value="BAND_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PHB" evidence="3">
        <location>
            <begin position="1"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="241" mass="26176" checksum="8C82B09509DFD58B" modified="2010-01-19" version="1">MEQVLDIPAQEVISRDNANVTIDAVCFIQVFDAAKAAYEVSDLESAIRNLTLTNIRTVLGSMELDEMLSQRDTINGRLLTIVDQATNPWGIKVTRIEIRDVQPPADLTAAMNAQMKAERNKRAEILEAEGVRQAQILRAEGQKQSEILKAEGEKQAAILQAEARERAAEAEAKATSMVSEAIAKGDVNAVNYFVAQGYTEALKTIGKSENNKVIMMPLETTGLMGSVAGIAELLSSKDKGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4R3</accession>
    <name>D0Z4R3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Trimethylamine-N-oxide reductase</fullName>
            <ecNumber evidence="4">1.7.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">VDA_000521</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
            <dbReference type="ChEBI" id="CHEBI:60539"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.7.2.3" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304606.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000521"/>
    <dbReference type="EnsemblBacteria" id="EEZ39501">
        <property type="protein sequence ID" value="EEZ39501"/>
        <property type="gene ID" value="VDA_000521"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0243">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="88184at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043546">
        <property type="term" value="F:molybdopterin cofactor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050626">
        <property type="term" value="F:trimethylamine-N-oxide reductase (cytochrome c) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006658">
        <property type="entry name" value="BisC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041460">
        <property type="entry name" value="Molybdopterin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006657">
        <property type="entry name" value="MoPterin_dinucl-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006656">
        <property type="entry name" value="Mopterin_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006655">
        <property type="entry name" value="Mopterin_OxRdtase_prok_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019546">
        <property type="entry name" value="TAT_signal_bac_arc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00384">
        <property type="entry name" value="Molybdopterin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18364">
        <property type="entry name" value="Molybdopterin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01568">
        <property type="entry name" value="Molydop_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="SSF50692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00509">
        <property type="entry name" value="bisC_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01409">
        <property type="entry name" value="TAT_signal_seq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00490">
        <property type="entry name" value="MOLYBDOPTERIN_PROK_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-0574">Periplasm</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003020011" description="Trimethylamine-N-oxide reductase" evidence="10">
        <location>
            <begin position="33"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="domain" description="Molybdopterin_N" evidence="13">
        <location>
            <begin position="42"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="Molybdopterin" evidence="11">
        <location>
            <begin position="86"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="domain" description="Molydop_binding" evidence="12">
        <location>
            <begin position="676"/>
            <end position="788"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF18364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEZ39501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="815" mass="90273" checksum="560C5DDB39CBE241" modified="2010-01-19" version="1">MTSLSRRSFLKGASASAGALAISNITALPAWAEEKATSAILSSTRWGPVMVTVENGKIISSTNALPQTVANSLQTTAKDQVHTKARVKYPMVRKGFLENPSAPQGLRGKDEFVRVSWEQALQLIHQQHQRIRTTYGAESVFAGSYGWRSSGVLHKAQTLLQRYMSMAGGYSGHLGDYSTGAAQVIMPHVVGSIEVYEQQTTFPVVMENSDVVVLWGLNPLNTLKIAWSSSDCSGLEFFHQLKKSNKTIIAIDPMRSETIEFFGDNVQWIAPHPSTDVAMMLGIAYALVDKKQHDVAFINKYTTGYDKFEAYLLGKSDGVTKTPQWAEQICGVPAKQLEILAEMFSKNRTMLMAGWGMQRQQYGEQRHWMLVTLASMLGQIGLPGGGFGFSYHYSNGGNPTRDAGVLPAISAAIDGASSAGNDWAISGAINSFPVARIVEALENPGQTYQHNGHERTFPEIKMIWWAGGANFTHHQETNRLIQAWQKPELIVISEPYWTAAAKHADIVLPITTSFERNDLTMTGDYSNQHLVPMKQVVPPQFESRNDFDVFADMAELLKPGGRAVFTENKTEMEWLNGFYKEAQAIGRQNRIAMPNFSYFWKQNKLIEMKWNTNNAKFVRYQAFRDNPIMNPLGTPSGKIEIYSQTIDGYNYPDCPPHPTWLEPNEWVGNAKDGEMQLMTSHATDRLHSQLNYAHLRENYAIANREPIWINPEDAKTFGIKTGDLVRAYNHRGQVLVGALVTNGIKKGSVCIHEGAWPDLDPTTGICRNGGCNVLTGDIPTSRLANGCAGNSSVVKIEKYTGPVLPLEAFTPPQNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4T5</accession>
    <name>D0Z4T5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000168</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39152">
        <property type="protein sequence ID" value="EEZ39152"/>
        <property type="gene ID" value="VDA_000168"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="43" mass="4322" checksum="932F4BD6C6AE2752" modified="2010-01-19" version="1">MTVTGLAVSAVTGFITKNWFAAIGGFFAGMIFLNVAAGVIGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4T7</accession>
    <name>D0Z4T7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000170"/>
    <dbReference type="EnsemblBacteria" id="EEZ39154">
        <property type="protein sequence ID" value="EEZ39154"/>
        <property type="gene ID" value="VDA_000170"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0582">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="763914at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007069">
        <property type="entry name" value="Transposase_32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026889">
        <property type="entry name" value="Zn_Tnp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04986">
        <property type="entry name" value="Y2_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14319">
        <property type="entry name" value="Zn_Tnp_IS91"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn_Tnp_IS91" evidence="1">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="364" mass="42816" checksum="8466C3032727F8E2" modified="2010-01-19" version="1">MLACGTSKVGSKHYECENPSCEHRKVIYNSCKSKACSSCGVMLTEKWIAKQLSILPKCEYQHMTLTMPDKLWPIFRLNPWLINLLYRCAVSAFLSFAKKRGIEIGLFCVVHTFGRQLNWNVHFHLSVTRGGVNLKTKRWGNIYFNAAMVEQHWKQQVVSFLRDHYNALNTKHDNYQHIRDFRGWSQFLSSQYSRKWRIHLAKKTEDVGPTVRYLGRYFKRPPIAASRLRHYQGGDVHFVYKDHRDNCYKTLVLSQIEMIDRLVSHIPAEKNFRAIRYYGFLSNRKRGEALPLVYDLLDQEEPVEPKPLNYAQMMHHLVRIDPYKCILCGGRMCFVKMEIGLKGHELVALRKATIREKRRLRYGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4V2</accession>
    <name>D0Z4V2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative type III secretion protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000185</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000185"/>
    <dbReference type="EnsemblBacteria" id="EEZ39169">
        <property type="protein sequence ID" value="EEZ39169"/>
        <property type="gene ID" value="VDA_000185"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5032XY1">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013348">
        <property type="entry name" value="T3SS_YscG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09477">
        <property type="entry name" value="Type_III_YscG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="68" mass="7296" checksum="D1908A86F203D62A" modified="2010-01-19" version="1">MNRGRYEEAHRLLEPVCVNSPDLVCLAALAAGKAGLASKAESWLAMASKGSEENQAFATSFSQDIRNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4X3</accession>
    <name>D0Z4X3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000206</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306603.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39190">
        <property type="protein sequence ID" value="EEZ39190"/>
        <property type="gene ID" value="VDA_000206"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5033ZJN">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2104951at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044899">
        <property type="entry name" value="SptP_N_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="556" mass="61384" checksum="7A9B73F2CAEB2849" modified="2010-01-19" version="1">MAIQLQQFLSVAKNNTVVANQNNQGEVTLKSGRFEGKTLYPFAKHTQTQSNLNLQTMGLFLNSLQKEYGSDITSHLASKLDITSGSKPLSGKVIQTIIGEANAISKAMTAFNAQAVHDFIASSNGAQKLLANNDHEQWLAPNNAAGKQFEGLLHEACDKQHHQLTQREIAEIAQTVVDDIHRLPQGIQEDFNQVADAFNQKDHYQVLHNLDNCAQKIMLRAQFDLADVDKQKLGADDKSGYQQHIVSELTQGLSQTQASDLLNSILNHPTSKELVQLLNSPGFKMQVMDDLEQADIPHEEQLLTLTKLCRTETLLDALITELDKRAHGSDKASQRLNDWVSYYGQGIGAGEISASDPEFASAFLTMQANDNHLNLDDCGLTQEPVAAQTKQYVTLTNPTAVTNALKEIAAKVDEKRSEQFEKDFDRATYLVDGAQISRNEDSTLDDISKIPTGVSYFANQELFASVLISLMNEQGITPIGDPTSTFNLYNKEDGTMELHAQLDMQLKMMIGLNEEPLDPDKSSLHLEVNLTIAAHNSQIDAKLNGPINVDYRADPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z515</accession>
    <name>D0Z515_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Resolvase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_000248</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306727.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000248"/>
    <dbReference type="EnsemblBacteria" id="EEZ39232">
        <property type="protein sequence ID" value="EEZ39232"/>
        <property type="gene ID" value="VDA_000248"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1961">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1791095at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000150">
        <property type="term" value="F:DNA strand exchange activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006118">
        <property type="entry name" value="Recombinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006119">
        <property type="entry name" value="Resolv_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036162">
        <property type="entry name" value="Resolvase-like_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00239">
        <property type="entry name" value="Resolvase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00857">
        <property type="entry name" value="Resolvase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53041">
        <property type="entry name" value="SSF53041"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00397">
        <property type="entry name" value="RECOMBINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51736">
        <property type="entry name" value="RECOMBINASES_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0229">DNA integration</keyword>
    <keyword evidence="3" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Resolvase/invertase-type recombinase catalytic" evidence="6">
        <location>
            <begin position="2"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-serine intermediate" evidence="4 5">
        <location>
            <position position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR606118-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="213" mass="24876" checksum="45132FEAB91687C5" modified="2010-01-19" version="1">MFIRAYLRASTEDQFADRAKEMLDQFAQERGHKIASYYRENISGTKLDRPELGRLLMDSHRNDILLVEQIDRLTRLSNSDWTTLKRQIEQHELRIVSLDVPTSWQALLDKDPSQTDPITHAVITAINNMLIDLMATMSHKDWLSRRQRQKQGIERAHSLGKYRGKQADQERHEKVMYYRLVKKLSIRETADATGYSTSQVCRIQALYREPTSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z578</accession>
    <name>D0Z578_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">IncF plasmid conjugative transfer pilus assembly protein TraW</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000038</name>
        <name evidence="3" type="ORF">VDA_000128</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000005">
        <property type="protein sequence ID" value="EEZ39053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306925.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000005.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000038"/>
    <dbReference type="EnsemblBacteria" id="EEZ39053">
        <property type="protein sequence ID" value="EEZ39053"/>
        <property type="gene ID" value="VDA_000038"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39112">
        <property type="protein sequence ID" value="EEZ39112"/>
        <property type="gene ID" value="VDA_000128"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031QWG">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1325284at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014114">
        <property type="entry name" value="TraW"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02743">
        <property type="entry name" value="TraW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5007650155" evidence="1">
        <location>
            <begin position="19"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="229" mass="25846" checksum="B918C5C796EB3D0D" modified="2010-01-19" version="1">MKPWPLIAALLLSPVLHAKSLGNIAPTFSIIEIDMLDWINARLTHYQETGEMDAMEARFKEQVKQSVKRPVPVAGITPTTNPTTFTVDPTLTLAADIKDNKGKVLFKKGLKINPFNAKTWPNGQALPHLQLSKQLVFLDGDDKRQLNFAKRYLANERAKAKPLPIKWVLINGAPETVFQFLGERIYFDQLGNITRQLKVKHVPSVAMQDGFAWKIQEFDISNESLTLDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z596</accession>
    <name>D0Z596_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ISSod13 transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000146</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39130">
        <property type="protein sequence ID" value="EEZ39130"/>
        <property type="gene ID" value="VDA_000146"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2801">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="172" mass="20029" checksum="4F46965245EBB3CF" modified="2010-01-19" version="1">MRSIWLRNDLENFKNRLLALEKQVNENGIILTDEQVAALERKKHDDEACGEIETAHPGYLGSQDTFYVGNLKGVERIYQQTFVDTYSKVAFAKLYTTKTPITAADMLNEFYQVTFRKKLYGSMEELQKDLDEWMDYYNNHRTHQGKMCCGRTPIETLEDGKSIWAEKNLAQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVI1</accession>
    <name>D0YVI1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Isochorismate synthase MenF</fullName>
            <ecNumber evidence="4">5.4.4.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Isochorismate mutase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">menF</name>
        <name evidence="6" type="ORF">VDA_001561</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the conversion of chorismate to isochorismate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>chorismate = isochorismate</text>
            <dbReference type="Rhea" id="RHEA:18985"/>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
            <dbReference type="ChEBI" id="CHEBI:29780"/>
            <dbReference type="EC" id="5.4.4.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Quinol/quinone metabolism; 1,4-dihydroxy-2-naphthoate biosynthesis; 1,4-dihydroxy-2-naphthoate from chorismate: step 1/7.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Quinol/quinone metabolism; menaquinone biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the isochorismate synthase family.</text>
    </comment>
    <dbReference type="EC" id="5.4.4.2" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001561"/>
    <dbReference type="EnsemblBacteria" id="EEZ40535">
        <property type="protein sequence ID" value="EEZ40535"/>
        <property type="gene ID" value="VDA_001561"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1169">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00079"/>
    <dbReference type="UniPathway" id="UPA01057">
        <property type="reaction ID" value="UER00163"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008909">
        <property type="term" value="F:isochorismate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009234">
        <property type="term" value="P:menaquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01935">
        <property type="entry name" value="MenF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005801">
        <property type="entry name" value="ADC_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015890">
        <property type="entry name" value="Chorismate_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004561">
        <property type="entry name" value="IsoChor_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034681">
        <property type="entry name" value="MenF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044250">
        <property type="entry name" value="MenF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47253">
        <property type="entry name" value="PTHR47253"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00425">
        <property type="entry name" value="Chorismate_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56322">
        <property type="entry name" value="SSF56322"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00543">
        <property type="entry name" value="isochor_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0474">Menaquinone biosynthesis</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chorismate_bind" evidence="5">
        <location>
            <begin position="176"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="195"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="245"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="289"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="423"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005297"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="465" mass="52644" checksum="263B6C88456CAB9D" modified="2010-01-19" version="1">MVQCELSEVTLTALQQAVEHLIAKIQQAKQTTHRVMVQLDLPIQAELIDWMENQPVFPKFYWQSRDGQEEVVALGQVKTFTDPLAAEKMIHDDQRVWGGRSFDGRTDRNRRCLSAFFFLPQLEIMRHGQTWSVAINLGDDYQKVLDGLAKLRFSSVVVDEISSRIVNRTYAPDFSGWASMIGQALDAISHKVFEKVVLARRTTLQLDTPVTPAQMMKASRANNSNSFHFMMALDAQHCFIGSTPERLFQRHDHALQTEALAGTIGRGKTAREDDELASWLMNDNKNGYENQLVVDDIVSRLNSCSHSLHVAHQPELVRLRKVQHIKRHIEAELNPQVFNTELLHNLQPTAAIAGLPREKAMEFISEHEPFSRGWYSGAVGYLSRQHSEFCVAIRSALIAGEELHLFAGAGIVPGSDPSSEWKELNRKTSTLCSLFESLPSDIEAKKASIMQLETWEQNEKWQQTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVM1</accession>
    <name>D0YVM1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">tRNA 2-selenouridine synthase</fullName>
            <ecNumber evidence="2">2.9.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">selU</name>
        <name evidence="4" type="ORF">VDA_001590</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>(2E)-geranyl diphosphate + 5-methylaminomethyl-2-thiouridine(34) in tRNA + H(+) + H2O + selenophosphate = (2E)-thiogeraniol + 5-methylaminomethyl-2-selenouridine(34) in tRNA + diphosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:42716"/>
            <dbReference type="Rhea" id="RHEA-COMP:10195"/>
            <dbReference type="Rhea" id="RHEA-COMP:10196"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16144"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58057"/>
            <dbReference type="ChEBI" id="CHEBI:74455"/>
            <dbReference type="ChEBI" id="CHEBI:82743"/>
            <dbReference type="ChEBI" id="CHEBI:143703"/>
            <dbReference type="EC" id="2.9.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>(2E)-geranyl diphosphate + 5-methylaminomethyl-2-thiouridine(34) in tRNA = 5-methylaminomethyl-S-(2E)-geranyl-thiouridine(34) in tRNA + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:14085"/>
            <dbReference type="Rhea" id="RHEA-COMP:10195"/>
            <dbReference type="Rhea" id="RHEA-COMP:14654"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58057"/>
            <dbReference type="ChEBI" id="CHEBI:74455"/>
            <dbReference type="ChEBI" id="CHEBI:140632"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>5-methylaminomethyl-2-(Se-phospho)selenouridine(34) in tRNA + H2O = 5-methylaminomethyl-2-selenouridine(34) in tRNA + phosphate</text>
            <dbReference type="Rhea" id="RHEA:60176"/>
            <dbReference type="Rhea" id="RHEA-COMP:10196"/>
            <dbReference type="Rhea" id="RHEA-COMP:15523"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:82743"/>
            <dbReference type="ChEBI" id="CHEBI:143702"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>5-methylaminomethyl-S-(2E)-geranyl-thiouridine(34) in tRNA + H(+) + selenophosphate = (2E)-thiogeraniol + 5-methylaminomethyl-2-(Se-phospho)selenouridine(34) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:60172"/>
            <dbReference type="Rhea" id="RHEA-COMP:14654"/>
            <dbReference type="Rhea" id="RHEA-COMP:15523"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16144"/>
            <dbReference type="ChEBI" id="CHEBI:140632"/>
            <dbReference type="ChEBI" id="CHEBI:143702"/>
            <dbReference type="ChEBI" id="CHEBI:143703"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SelU family.</text>
    </comment>
    <dbReference type="EC" id="2.9.1.3" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298334.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001590"/>
    <dbReference type="EnsemblBacteria" id="EEZ40563">
        <property type="protein sequence ID" value="EEZ40563"/>
        <property type="gene ID" value="VDA_001590"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2603">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1052499at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016765">
        <property type="term" value="F:transferase activity, transferring alkyl or aryl (other than methyl) groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043828">
        <property type="term" value="F:tRNA 2-selenouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01622">
        <property type="entry name" value="tRNA_sel_U_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017582">
        <property type="entry name" value="SelU"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03167">
        <property type="entry name" value="tRNA_sel_U_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0711">Selenium</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Rhodanese" evidence="3">
        <location>
            <begin position="13"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="active site" description="S-selanylcysteine intermediate" evidence="2">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="364" mass="41523" checksum="5DDDAC0E653290A3" modified="2010-01-19" version="1">MSRPNCEDFRQLFVNDVPLMDMRAPIEFEQGAFPMSTNLPLMTNSEREAVGTCYKEQGQDAAIALGHELVCGDVKAQRVAQWKAFCEANPNGYLYCFRGGQRSQITQLWLKEAGIDYPYVVGGYKALRRFLIDTIDQVAEMPMLIVGGNTGSGKTIMVNELANGIDLEGAAHHRGSSFGRFATEQHTQIAFENNLAVQMLKKLDHGMTSFVYEDEGRHIGSVNLPVSLHEQMKQAKVAVVQDPMDVRLERLMDDYVIRMQRDFVALHGEEEGWFEFSEYLSHSMMGIHRRLGHERYEQLVEAQKQAVAQMRATGSVDGHYAWLQPLLEQYYDPMYTYQLEKKAERIVFRGDYQTVKEWLAAQAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVV9</accession>
    <name>D0YVV9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative cI prophage repressor protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299248.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002040"/>
    <dbReference type="EnsemblBacteria" id="EEZ41008">
        <property type="protein sequence ID" value="EEZ41008"/>
        <property type="gene ID" value="VDA_002040"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1974">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1933795at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06529">
        <property type="entry name" value="S24_LexA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039418">
        <property type="entry name" value="LexA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015927">
        <property type="entry name" value="Peptidase_S24_S26A/B/C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00717">
        <property type="entry name" value="Peptidase_S24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="SSF51306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="11"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="220" mass="24506" checksum="96F7CBB7E8D4260A" modified="2010-01-19" version="1">MDKKTEVGLRLKQFRAKRGISQKDLADLCGWGASRVSNYESGIRSISLDDADTLAKHLGIKAYQILFDDSELPELMNISTIDIQPSYQNSFPVLSSVQAGIWTEACEPYPVETITEWYQTTERTSKNSFWLRVHGDSMTSPTGISFPEGTLVLVDTERAAENGSLVAAKLTDVNEATFKKLMIDAGQRYLKPLNPQYPTLPINGNCRIIGVIVDAKLRLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVW1</accession>
    <name>D0YVW1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA replication protein dnaC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002042</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002042"/>
    <dbReference type="EnsemblBacteria" id="EEZ41010">
        <property type="protein sequence ID" value="EEZ41010"/>
        <property type="gene ID" value="VDA_002042"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1484">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1792718at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028350">
        <property type="entry name" value="DNAC/ATP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002611">
        <property type="entry name" value="IstB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01695">
        <property type="entry name" value="IstB_IS21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003073">
        <property type="entry name" value="DNAC_TnpB_IstB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IstB_IS21" evidence="1">
        <location>
            <begin position="98"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="241" mass="27637" checksum="5570E2CE7AAC6EBD" modified="2010-01-19" version="1">MNFMQRLAQAMPANVKPYTFEQMQAIRQREAESYCQSISQENRQARVSMAIGRSGIKKRHQNCRFDNYYTHCEGQRSAFAEAKRLLDNFVNRRTCGGFIFAGTSGTGKNHLACAIANEMLQLRRSVVVITVAELMLKIRDSYRKESDVSETDIIRFLSQVDLLVIDELGVQHNSNNERVMINRIIDERYTLEKPTGVITNLQSAELTNTLGRAAVDRIMEDGKWVTFNWTSYRTNKGMHQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVY3</accession>
    <name>D0YVY3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Small-conductance mechanosensitive channel</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_001243</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homoheptamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell inner membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the MscS (TC 1.A.23) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297712.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40221">
        <property type="protein sequence ID" value="EEZ40221"/>
        <property type="gene ID" value="VDA_001243"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3264">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1903165at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008381">
        <property type="term" value="F:mechanosensitive ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045275">
        <property type="entry name" value="MscS_archaea/bacteria_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011066">
        <property type="entry name" value="MscS_channel_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006686">
        <property type="entry name" value="MscS_channel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011014">
        <property type="entry name" value="MscS_channel_TM-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008910">
        <property type="entry name" value="TM_helix"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30221">
        <property type="entry name" value="PTHR30221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05552">
        <property type="entry name" value="TM_helix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82689">
        <property type="entry name" value="SSF82689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82861">
        <property type="entry name" value="SSF82861"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01246">
        <property type="entry name" value="UPF0003"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0407">Ion channel</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="77"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="110"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU369025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ40221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="294" mass="31755" checksum="2BB5BB1EF885F697" modified="2010-01-19" version="1">MSENVAEKVVDKITDNSLTDGVMHAGNWIADNQDLLIQYAVNLVSALLILFIGNIAVKMIAGGVAKMLRKKDMDNAVVEFIHGLVRYTLFVIVLIAALSRVGVQTASVVAVIGAAGLAVGLALQGSLSNFAAGVLIVAFRPFKSGDFVEVAGVSGSVESIQIFSTELRTPDNKTVVVPNSSIIGNPITNYSRNATRRVDLTIGVSYKADLQQTKEVLTRVVKADERVLQDPEPTIGVVALADSSVNFVVRPWVKTADYWAVYFDLTQAIKEELDKEGIEIPFPQMDVHLNKIEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVZ6</accession>
    <name>D0YVZ6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 9 10">2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase</fullName>
            <shortName evidence="9">MECDP-synthase</shortName>
            <shortName evidence="9">MECPP-synthase</shortName>
            <shortName evidence="9">MECPS</shortName>
            <ecNumber evidence="5 9 10">4.6.1.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ispF</name>
        <name evidence="12" type="ORF">VDA_001275</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9 10">
            <text>4-CDP-2-C-methyl-D-erythritol 2-phosphate = 2-C-methyl-D-erythritol 2,4-cyclic diphosphate + CMP</text>
            <dbReference type="Rhea" id="RHEA:23864"/>
            <dbReference type="ChEBI" id="CHEBI:57919"/>
            <dbReference type="ChEBI" id="CHEBI:58483"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="EC" id="4.6.1.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="9">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 4/6.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 9">Homotrimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9 10">Belongs to the IspF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.12" evidence="5 9 10"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297766.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001275"/>
    <dbReference type="EnsemblBacteria" id="EEZ40253">
        <property type="protein sequence ID" value="EEZ40253"/>
        <property type="gene ID" value="VDA_001275"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0245">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1716560at2"/>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00095"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008685">
        <property type="term" value="F:2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00554">
        <property type="entry name" value="MECDP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00107">
        <property type="entry name" value="IspF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003526">
        <property type="entry name" value="MECDP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020555">
        <property type="entry name" value="MECDP_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036571">
        <property type="entry name" value="MECDP_synthase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43181">
        <property type="entry name" value="PTHR43181"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02542">
        <property type="entry name" value="YgbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69765">
        <property type="entry name" value="SSF69765"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00151">
        <property type="entry name" value="ispF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01350">
        <property type="entry name" value="ISPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9 10" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="8 9 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YgbB" evidence="11">
        <location>
            <begin position="1"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="4-CDP-2-C-methyl-D-erythritol 2-phosphate binding" evidence="9">
        <location>
            <begin position="8"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="region of interest" description="4-CDP-2-C-methyl-D-erythritol 2-phosphate binding" evidence="9">
        <location>
            <begin position="34"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="4-CDP-2-C-methyl-D-erythritol 2-phosphate binding" evidence="9">
        <location>
            <begin position="56"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="4-CDP-2-C-methyl-D-erythritol 2-phosphate binding" evidence="9">
        <location>
            <begin position="61"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="4-CDP-2-C-methyl-D-erythritol 2-phosphate binding" evidence="9">
        <location>
            <begin position="132"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>4-CDP-2-C-methyl-D-erythritol 2-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57919"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>4-CDP-2-C-methyl-D-erythritol 2-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57919"/>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="9">
        <location>
            <position position="34"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="9">
        <location>
            <position position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ40253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="157" mass="16670" checksum="488712FEBDC59CC6" modified="2010-01-19" version="1">MRIGHGFDVHKFGGEGPVIIGGVAIPYEQGLIAHSDGDVALHAVCDALLGAIGAGDIGRHFPDTDAEWKGADSRFLLRDVYKKVKAKGYVLGNVDVTIIAQAPKMTPHIEAMCQAIADDLETEMSNVNVKATTSERLGFTGRKEGIACEAVVLIKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW18</accession>
    <name>D0YW18_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hypothetical lipoprotein NlpD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001278</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297772.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001278"/>
    <dbReference type="EnsemblBacteria" id="EEZ40256">
        <property type="protein sequence ID" value="EEZ40256"/>
        <property type="gene ID" value="VDA_001278"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4942">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1891666at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LysM" evidence="2">
        <location>
            <begin position="49"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="278" mass="30179" checksum="6D23C21C1753A25C" modified="2010-01-19" version="1">MSVIQKIVKPVGLIALSSVIFGCSSHTPAPVTSLTKDYSQLARGSFHGSDYVVQKGDTLYFISYIAGQDVKDLIAYNNLTPPYTIYPGQRLNVRGSNSYSTASRSTSTTVTKPVTQTKPAEQKTNNKKVDQNQAKEYSQKATDNKPVTKPVPKPVAPAVTGWLWPAKGKVISRFSSTNKGIDIAGSRGEAVNATAAGKVVYAGNALRGYGNLVIIKHNDDYLSAYAHNDKLLVKEQQQVTAGQKIALMGDTGADSVKLHFEIRYKGKSVDPLRYLPRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW58</accession>
    <name>D0YW58_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HesA/MoeB/ThiF family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001340</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297881.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001340"/>
    <dbReference type="EnsemblBacteria" id="EEZ40315">
        <property type="protein sequence ID" value="EEZ40315"/>
        <property type="gene ID" value="VDA_001340"/>
    </dbReference>
    <dbReference type="GeneID" id="57339759"/>
    <dbReference type="eggNOG" id="COG1179">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1543144at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008641">
        <property type="term" value="F:ubiquitin-like modifier activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43267">
        <property type="entry name" value="PTHR43267"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="SSF69572"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="239"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="ThiF" evidence="2">
        <location>
            <begin position="22"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="267" mass="29173" checksum="10D24A0A57E23071" modified="2010-01-19" version="1">MRELDTPASDSYNQRFGGTRRLYGNSEVEILRASHVCVIGVGGVGSWAAEALARSGIGEITLIDMDDVCVTNINRQIHAMTGTVGQSKIEVMAQRIALINPECKVNLIDDFITPENLAEYIGPQFDYVLDAIDSMKPKAALLAYCKRHKIKVITTGGAGGQTDPTQIQIADLTKTIQDPLAKKLRDTLRRFYNFSKTRKFGIECVFSTEQLKYPQADGSVCNAKATAEGPKRMDCASGFGAATVVTATFGFVAVSRIIQKLTEQKRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW60</accession>
    <name>D0YW60_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal RNA large subunit methyltransferase M</fullName>
            <ecNumber evidence="6">2.1.1.186</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">23S rRNA (cytidine2498-2'-O)-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">23S rRNA 2'-O-ribose methyltransferase RlmM</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rlmM</name>
        <name evidence="11" type="ORF">VDA_001345</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>cytidine(2498) in 23S rRNA + S-adenosyl-L-methionine = 2'-O-methylcytidine(2498) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42788"/>
            <dbReference type="Rhea" id="RHEA-COMP:10244"/>
            <dbReference type="Rhea" id="RHEA-COMP:10245"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74495"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.186"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="6">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.186" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297891.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001345"/>
    <dbReference type="EnsemblBacteria" id="EEZ40320">
        <property type="protein sequence ID" value="EEZ40320"/>
        <property type="gene ID" value="VDA_001345"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2933">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="902245at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01551">
        <property type="entry name" value="23SrRNA_methyltr_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040739">
        <property type="entry name" value="RlmM_FDX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002877">
        <property type="entry name" value="RNA_MeTrfase_FtsJ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011224">
        <property type="entry name" value="rRNA_MeTrfase_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01728">
        <property type="entry name" value="FtsJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18125">
        <property type="entry name" value="RlmM_FDX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028774">
        <property type="entry name" value="UCP028774"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6 11" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5 6 8" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RlmM_FDX" evidence="10">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="FtsJ" evidence="9">
        <location>
            <begin position="186"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="6 8">
        <location>
            <begin position="221"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6 7">
        <location>
            <position position="306"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6 8">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 8">
        <location>
            <position position="240"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 8">
        <location>
            <position position="260"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 8">
        <location>
            <position position="277"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR028774-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR028774-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF18125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ40320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="362" mass="41536" checksum="579DBA557FEE878E" modified="2010-01-19" version="1">MNQVLLYCRPGFEKECAGEVQDKANKLELYGFPRVKNNTGYVVFEFYQQGDGDKFIQLQPFAELIFARQMIAVSPLLADLPADDRISPILSAISEDFPRCGDIRIETPDTNDAKELSKFCRKFTVPLRAALRKADVLYTKDNPKKPVLHVCFIAPGCCYVGYSYSNNNSPFFMGIPRLKFPADAPSRSTLKLEEAFHVFIPREEWDERLAPGMWGVDLGACPGGWTYQLVKRSMFVHSIDNGQMAQSLMDTGQVRHHEVDGFKFEPPRKNVTWIVCDMVEKPARVAHLMGEWICKGWAREAIFNLKLPMKGRYDEVLQDIENLKLFLIKNGVKFSLQAKHLYHDREEITVHLRCLDNRLHIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWA1</accession>
    <name>D0YWA1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Cell division protein FtsA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ftsA</name>
        <name evidence="8" type="ORF">VDA_001179</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Self-interacts. Interacts with FtsZ.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
            <orientation evidence="5">Cytoplasmic side</orientation>
        </subcellularLocation>
        <text evidence="5">Localizes to the Z ring in an FtsZ-dependent manner. Targeted to the membrane through a conserved C-terminal amphipathic helix.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the FtsA/MreB family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297582.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001179"/>
    <dbReference type="EnsemblBacteria" id="EEZ40157">
        <property type="protein sequence ID" value="EEZ40157"/>
        <property type="gene ID" value="VDA_001179"/>
    </dbReference>
    <dbReference type="GeneID" id="57339966"/>
    <dbReference type="eggNOG" id="COG0849">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1044637at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009898">
        <property type="term" value="C:cytoplasmic side of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043093">
        <property type="term" value="P:FtsZ-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02033">
        <property type="entry name" value="FtsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020823">
        <property type="entry name" value="Cell_div_FtsA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003494">
        <property type="entry name" value="SHS2_FtsA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02491">
        <property type="entry name" value="SHS2_FTSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003101">
        <property type="entry name" value="FtsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00842">
        <property type="entry name" value="FtsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01174">
        <property type="entry name" value="ftsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 5 6" id="KW-0132">Cell division</keyword>
    <keyword evidence="1 5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FtsA" evidence="7">
        <location>
            <begin position="10"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR003101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ40157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="419" mass="45284" checksum="B4428F5873460397" modified="2010-01-19" version="1">MTKAADKKLIVGLDIGTSKVCALVGEILPDGNVNVIGVGNSPSKGMDKGGVNDLESVVKSVQRAIDQAELMIDDFQISSVYLSLSGKHIRCQTEKGMVPISDKEVTQDDVDNVIHTAKSVKISDEHRTLHVIPQEFAIDYQEGIKNPVGLSGVRMEASVHMITCHNDMARNIVKAVERCGLKVEQLIFSGLAASHAVLTPDERELGVCVIDIGGGTMDIAVWSGGALRHAEVIPYAGNVVTSDIAYAFGTPPGDAEEIKVRYGCALSELVSKDAKVDVPSVGGRPSRSLQSQTLAEVIEPRYTELLGLVNQKLVVIQEQLRETGVKHHLAAGIVLTGGAAQMEGLIECAERVFRNQVRIGQPLEIHGLTDYVQSPHFATAVGLLHYGKDSQTFDDSDVETKRSVTGFFSRFSGWLRKEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWA8</accession>
    <name>D0YWA8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cell division protein ZapD</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Z ring-associated protein D</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">zapD</name>
        <name evidence="6" type="ORF">VDA_001186</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Interacts with FtsZ.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="5">Localizes to mid-cell in an FtsZ-dependent manner.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the ZapD family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297594.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001186"/>
    <dbReference type="EnsemblBacteria" id="EEZ40164">
        <property type="protein sequence ID" value="EEZ40164"/>
        <property type="gene ID" value="VDA_001186"/>
    </dbReference>
    <dbReference type="GeneID" id="57339959"/>
    <dbReference type="eggNOG" id="COG4582">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1453477at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000917">
        <property type="term" value="P:division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043093">
        <property type="term" value="P:FtsZ-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01092">
        <property type="entry name" value="ZapD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009777">
        <property type="entry name" value="ZapD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027462">
        <property type="entry name" value="ZapD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036268">
        <property type="entry name" value="ZapD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39455">
        <property type="entry name" value="PTHR39455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07072">
        <property type="entry name" value="ZapD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160950">
        <property type="entry name" value="SSF160950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 5" id="KW-0132">Cell division</keyword>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0717">Septation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="245" mass="29077" checksum="9C7F56D331CCD510" modified="2010-01-19" version="1">MQNTRFEHPLNEKVRIYLRLEFLLHQMTHSCQLHDPWQHQIFFRALFELLEILDQVQVKADLAKDLEKQRNKFKNWLNLDGVDQQALQNVIDEMEQIQRKLLASCRLGQELRDDRFLSGIKQRFSIPGGSCSFDLPTLHHWLHLPLERRQQDLKQWLGHLSCLSQALNLWLRLIRDSSQYKPQVSRNGFFQYDTSDANLLRLEICPSYDVYPMISGHRSRFAIRFLPFTEEGKVAETIEFKLAIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWE4</accession>
    <name>D0YWE4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001392</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297989.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001392"/>
    <dbReference type="EnsemblBacteria" id="EEZ40367">
        <property type="protein sequence ID" value="EEZ40367"/>
        <property type="gene ID" value="VDA_001392"/>
    </dbReference>
    <dbReference type="GeneID" id="57339688"/>
    <dbReference type="eggNOG" id="COG3021">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1387978at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018627" evidence="1">
        <location>
            <begin position="18"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="287" mass="32135" checksum="F803CB9A6896A2BF" modified="2010-01-19" version="1">MARYAKVVAGISVVAGALGFTAFNSTFDVAPEPEVTNEIIAPKFSYHCMEAHGVQPLDHDGQLTVSVWNIYKQQRPNWQQALDNISQHSELVLLQEATLKPELKQYLQDKPWKVRMANAFRFLDTPAGVMNLSKVEAMKTCAYLAMEPWLRLPKSALLSQFALSNGQTLAVVNLHGVNFAMGLEEYKAQFKSLASALQKHVGPVILAGDFNTWRKGRMDVVKQFAHQLGLKEVQFRQDQRIKVFGKPLDHLFYRGLVLETAEAPKTDASDHNPIIATFRLRSAATVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWE6</accession>
    <name>D0YWE6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Membrane-bound lytic murein transglycosylase D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001394</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297991.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001394"/>
    <dbReference type="EnsemblBacteria" id="EEZ40369">
        <property type="protein sequence ID" value="EEZ40369"/>
        <property type="gene ID" value="VDA_001394"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0741">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1388">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1444566at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008258">
        <property type="entry name" value="Transglycosylase_SLT_dom_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01464">
        <property type="entry name" value="SLT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="SSF54106"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019846" evidence="2">
        <location>
            <begin position="25"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="3">
        <location>
            <begin position="343"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="3">
        <location>
            <begin position="407"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="3">
        <location>
            <begin position="468"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="516" mass="58282" checksum="899001E3604B235A" modified="2010-01-19" version="1">MKSRILLASALLLAGCQSTQQVNAPSTTTKKTIIIEKPVTTVPTSPSSVFETQSHQVPKKTTPQLSPQQQQDLWDRIAMQIDTPIPENKRIRYYRNWYLKHPRNLQIIAERSKPFLYYITQEVEKRNMPLELALLPIVESSFDQYAYSSSAAAGLWQIIPDTGRRFGLTINSWYDGRRDIVKSTQAALNLLEYLHNKFGNWQYALAAYNTGEGRVFNAIDKNKRLGKSTDYWNLDLPDETSAYVPKLYAVVDILRDPQKYGIRIPAVANKPVLQEINPGVQMDLAVAARFAGISTQELKDLNPAYHKWATAPNGQYHLLLPINKVKSFKVALANNKRENLRTVRHTVRSGDTLGALAVKYNTTVKDIQRANNLKSTQLRIGQHLSIGVKGASLVSKPKVSPSHTSSRTHTVKSGESLWNIAKKYNTNVANLRRWNNLSANSTLRIGQKLTVKHSVSNTSTKQSSVRWTQYKVRSGDSLSVIAQRHDVSVSELMKWNNISKRHYIKPGQTLKLRTKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWH8</accession>
    <name>D0YWH8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 9">tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase</fullName>
            <ecNumber evidence="8 9">2.8.4.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">(Dimethylallyl)adenosine tRNA methylthiotransferase MiaB</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">tRNA-i(6)A37 methylthiotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">miaB</name>
        <name evidence="13" type="ORF">VDA_001437</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>[sulfur carrier]-SH + AH2 + N(6)-dimethylallyladenosine(37) in tRNA + 2 S-adenosyl-L-methionine = 2-methylsulfanyl-N(6)-dimethylallyladenosine(37) in tRNA + 5'-deoxyadenosine + [sulfur carrier]-H + A + 2 H(+) + L-methionine + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:37067"/>
            <dbReference type="Rhea" id="RHEA-COMP:10375"/>
            <dbReference type="Rhea" id="RHEA-COMP:10376"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="ChEBI" id="CHEBI:74415"/>
            <dbReference type="ChEBI" id="CHEBI:74417"/>
            <dbReference type="EC" id="2.8.4.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="9">Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the methylthiotransferase family. MiaB subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.8.4.3" evidence="8 9"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298064.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001437"/>
    <dbReference type="EnsemblBacteria" id="EEZ40411">
        <property type="protein sequence ID" value="EEZ40411"/>
        <property type="gene ID" value="VDA_001437"/>
    </dbReference>
    <dbReference type="GeneID" id="57339638"/>
    <dbReference type="eggNOG" id="COG0621">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="397139at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035596">
        <property type="term" value="F:methylthiotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01864">
        <property type="entry name" value="tRNA_metthiotr_MiaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005839">
        <property type="entry name" value="Methylthiotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020612">
        <property type="entry name" value="Methylthiotransferase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013848">
        <property type="entry name" value="Methylthiotransferase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038135">
        <property type="entry name" value="Methylthiotransferase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006463">
        <property type="entry name" value="MiaB_methiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002792">
        <property type="entry name" value="TRAM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01938">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00919">
        <property type="entry name" value="UPF0004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00273">
        <property type="entry name" value="(dimethylallyl)adenosine_tRNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00089">
        <property type="entry name" value="TIGR00089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51449">
        <property type="entry name" value="MTTASE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01278">
        <property type="entry name" value="MTTASE_RADICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50926">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0408">Iron</keyword>
    <keyword evidence="7 9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 9 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="MTTase N-terminal" evidence="11">
        <location>
            <begin position="3"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="Radical SAM core" evidence="12">
        <location>
            <begin position="143"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="TRAM" evidence="10">
        <location>
            <begin position="378"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="12"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00033765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ40411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="474" mass="53485" checksum="4DC4AD8D180CF165" modified="2010-01-19" version="1">MAKKLLIKTWGCQMNEYDSSKMADLLNAANGFELTEDPEEADVLLLNTCSIREKAQEKVFHQLGRWKTLKDKKPGLVIGVGGCVATQEGDSIRQRAPYVDVIFGPQTLHRLPEMIKQSQSTEAPVMDISFPEIEKFDSLPEPRAEGPTAFVSIMEGCSKYCTYCVVPYTRGEEVSRPLDDVLFEIAQLAAQGVREVNLLGQNVNAYRGATYDGEIATFAELLRLVAAIDGIDRIRYTTSHPIEFTDDIIEVYQDTPELVSFLHLPVQSGSDRILTMMKRPHTAIEYKSKIRKLRKARPDITISSDFIVGFPGESDQDFQDTMKLIRDVDFDMSFSFIFSPRPGTPAADYPCDLTEEVKKERLYELQQQINSQAMRFSRQMLGTEQRILVEGPSKKNVMELRGRTENNRVVNFEGSADLIGQFVDVKITDVFANSLRGELIRTEAEMDLRVAMSPTEVMEKTRKEDDLGVGVYTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWH9</accession>
    <name>D0YWH9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Biosynthetic peptidoglycan transglycosylase</fullName>
            <ecNumber evidence="11">2.4.1.129</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Glycan polymerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Peptidoglycan glycosyltransferase MtgA</fullName>
            <shortName evidence="11">PGT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">mtgA</name>
        <name evidence="13" type="ORF">VDA_001438</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>[GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-di-trans,octa-cis-undecaprenyl diphosphate + beta-D-GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate = [GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-di-trans-octa-cis-undecaprenyl diphosphate + di-trans,octa-cis-undecaprenyl diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23708"/>
            <dbReference type="Rhea" id="RHEA-COMP:9602"/>
            <dbReference type="Rhea" id="RHEA-COMP:9603"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58405"/>
            <dbReference type="ChEBI" id="CHEBI:60033"/>
            <dbReference type="ChEBI" id="CHEBI:78435"/>
            <dbReference type="EC" id="2.4.1.129"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="11">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cell inner membrane</location>
            <topology evidence="11">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the glycosyltransferase 51 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.129" evidence="11"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001438"/>
    <dbReference type="EnsemblBacteria" id="EEZ40412">
        <property type="protein sequence ID" value="EEZ40412"/>
        <property type="gene ID" value="VDA_001438"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0744">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009274">
        <property type="term" value="C:peptidoglycan-based cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016763">
        <property type="term" value="F:pentosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008955">
        <property type="term" value="F:peptidoglycan glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3810.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00766">
        <property type="entry name" value="PGT_MtgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001264">
        <property type="entry name" value="Glyco_trans_51"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036950">
        <property type="entry name" value="PBP_transglycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011812">
        <property type="entry name" value="Pep_trsgly"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30400">
        <property type="entry name" value="PTHR30400"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00912">
        <property type="entry name" value="Transgly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02070">
        <property type="entry name" value="mono_pep_trsgly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 11" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1 11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 11" id="KW-0133">Cell shape</keyword>
    <keyword evidence="10 11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3 11" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 11" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Transgly" evidence="12">
        <location>
            <begin position="52"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ40412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="230" mass="26491" checksum="4796F799BF938932" modified="2010-01-19" version="1">MLDRIKRYLLILLLSLLIIPVIQIASLKYIDPPFWGWQIHRSLFPPKGYPTHRQHTWVDLNRISKNMQLAVIASEDQLFPSHYGFDINAILTVIKQTGANGPKRGASTITQQTAKNVFLFPAHSMIRKAVELYYAIWMEVIWGKQRILEMYLNVIEFGPGIFGVEAASQHFFNTKARYLTAQQAAQLAAVLPNPYKLKANPPSRYVLERSRWIRKQMRQLSMAAVNKLSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWJ9</accession>
    <name>D0YWJ9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">D-erythrose-4-phosphate dehydrogenase</fullName>
            <shortName evidence="5">E4PDH</shortName>
            <ecNumber evidence="5">1.2.1.72</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">epd</name>
        <name evidence="10" type="ORF">VDA_001240</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>D-erythrose 4-phosphate + H2O + NAD(+) = 4-phospho-D-erythronate + 2 H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:12056"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16897"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58766"/>
            <dbReference type="EC" id="1.2.1.72"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; pyridoxine 5'-phosphate biosynthesis; pyridoxine 5'-phosphate from D-erythrose 4-phosphate: step 1/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.72" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001240"/>
    <dbReference type="EnsemblBacteria" id="EEZ40218">
        <property type="protein sequence ID" value="EEZ40218"/>
        <property type="gene ID" value="VDA_001240"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0057">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00244">
        <property type="reaction ID" value="UER00309"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048001">
        <property type="term" value="F:erythrose-4-phosphate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042823">
        <property type="term" value="P:pyridoxal phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008615">
        <property type="term" value="P:pyridoxine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01640">
        <property type="entry name" value="E4P_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006422">
        <property type="entry name" value="E4P_DH_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020831">
        <property type="entry name" value="GlycerAld/Erythrose_P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020829">
        <property type="entry name" value="GlycerAld_3-P_DH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020828">
        <property type="entry name" value="GlycerAld_3-P_DH_NAD(P)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43148">
        <property type="entry name" value="PTHR43148"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02800">
        <property type="entry name" value="Gp_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00044">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000149">
        <property type="entry name" value="GAP_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00078">
        <property type="entry name" value="G3PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00846">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01532">
        <property type="entry name" value="E4PD_g-proteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5 7" id="KW-0520">NAD</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 5 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 5" id="KW-0664">Pyridoxine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gp_dh_N" evidence="9">
        <location>
            <begin position="17"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="173"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="232"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5 6">
        <location>
            <position position="174"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <begin position="26"/>
            <end position="27"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="255"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <position position="337"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="site" description="Activates thiol group during catalysis" evidence="5 8">
        <location>
            <position position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ40218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="360" mass="40082" checksum="03FBFC0C2435E19C" modified="2010-01-19" version="1">MLYTNAAWYFCSTDMTLRVAINGFGRIGRSVLRALYESDKYRHINVVAVNELAEPEAMVHLLQYDSSHGRFTKPVSYDREHLVVTHENGQQDRIAILHHDQIEQLPWHQLDVDIVLDCTGVYGSRSDGLAHIDAGARKVLFSHPATHDIDNTIIYGVNHDSLTPSQRIVSNGSCTTNCIVPIIDVLDKAFGIESGTITTIHSAMNDQQVIDAYHPDLRRTRAASQSIIPVDTKLHLGIGRIFPKFSDKFEAISVRVPTINVTAMDLSVTVKTNLKVNDINQSLSNASRCTLEGIIDYTEAPLVSIDFNHDPHSAIVDGTQTRVSNQHLVKVLVWCDNEWGFANRMLDTALAMHAVGYLDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX05</accession>
    <name>D0YX05_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002058</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299306.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41026">
        <property type="protein sequence ID" value="EEZ41026"/>
        <property type="gene ID" value="VDA_002058"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031NWR">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1851189at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="230" mass="25174" checksum="0BEF2118EE4F2B4B" modified="2010-01-19" version="1">MGLEQQISSLVQASENLTGAVNNKIGEIDKEVVAAKTKFEQFLGDADNRFMTRVGIYVHVSGDDDKFYPVYIPASHPGVTDLQINRSVHFDREWAGGLSAKFILQNSGWGGYPDIFVLDALGHVNHPTKTPIAVKTDGFIADYLNGGGFVAGAIFWLRGNHKYLISSSLRAFTGVITHEELVTTNIFEHGNIRIFKSGFHVTASSATVACEVKTARNQTKIPTLSYIRGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX49</accession>
    <name>D0YX49_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8 9">Dihydroorotase</fullName>
            <shortName evidence="8">DHOase</shortName>
            <ecNumber evidence="4 8 9">3.5.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">pyrC</name>
        <name evidence="11" type="ORF">VDA_001843</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>(S)-dihydroorotate + H2O = H(+) + N-carbamoyl-L-aspartate</text>
            <dbReference type="Rhea" id="RHEA:24296"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30864"/>
            <dbReference type="ChEBI" id="CHEBI:32814"/>
            <dbReference type="EC" id="3.5.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8 9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8 9">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8 9">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 3/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8 9">Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.3" evidence="4 8 9"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298800.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001843"/>
    <dbReference type="EnsemblBacteria" id="EEZ40811">
        <property type="protein sequence ID" value="EEZ40811"/>
        <property type="gene ID" value="VDA_001843"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0418">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1319925at2"/>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00117"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004151">
        <property type="term" value="F:dihydroorotase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019856">
        <property type="term" value="P:pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01294">
        <property type="entry name" value="DHOase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00219">
        <property type="entry name" value="PyrC_classII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004721">
        <property type="entry name" value="DHOdimr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002195">
        <property type="entry name" value="Dihydroorotase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43137">
        <property type="entry name" value="PTHR43137"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001237">
        <property type="entry name" value="DHOdimr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00856">
        <property type="entry name" value="pyrC_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00482">
        <property type="entry name" value="DIHYDROOROTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00483">
        <property type="entry name" value="DIHYDROOROTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 8 9" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="10">
        <location>
            <begin position="11"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="15"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="246"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" description="via carbamate group" evidence="8">
        <location>
            <position position="98"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="135"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="218"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="250"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="262"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-carboxylysine" evidence="8">
        <location>
            <position position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ40811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="342" mass="37581" checksum="797BAAA22D61235B" modified="2010-01-19" version="1">MTTITITRPDDWHVHLRDGDVLPDTVRDISRYMGRAIVMPNLIPPVIDTESALSYRDRILANHPTPTFSPLMTIYLTDNTTADEIYKAKESGHIYAAKLYPAGATTNSDSGVTSIDKVRPAIEAMQEVGMPLLIHGEVTHNHIDIFDREKTFLETVLGPIVDAFPTLKIVLEHITTKEAVEFVLNAGSNVGATITAHHLLFNRNHMLVGGIRPHFYCLPILKRNSHQEALIAAATSGNPKFFLGTDTAPHAKGRKEAACGCAGSYTAHAAIELYAEVFEQANALDKLEAFASFNGADFYGLPRNSDTITLTKEGWPVPEEMSFGNDVVVPIRAGEMMSWKVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX60</accession>
    <name>D0YX60_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator VpsT</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001849</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298812.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001849"/>
    <dbReference type="EnsemblBacteria" id="EEZ40817">
        <property type="protein sequence ID" value="EEZ40817"/>
        <property type="gene ID" value="VDA_001849"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="930905at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="149"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="219" mass="25432" checksum="65010887C6A151BE" modified="2010-01-19" version="1">MSQKKFNLLLIGLKTMNTELIINQINNNRLNNISFRNISNFNYDFKTSSYDLIIIDHHAISINENINKLLESKDSETPILIFNIDTDITTDTLLSWPKVKGILSKDSPIEHLIKSIAVVIEHGLWLPRQTLEQMLDYYRNHKPSNDTRLLPTQPLLTRREKQILGLLTEGKTNIEIAETLFVAETTVKSHIYNLYKKIDVKCRKEAIFKVKQLRPESML</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX66</accession>
    <name>D0YX66_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glutaredoxin 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001831</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298783.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001831"/>
    <dbReference type="EnsemblBacteria" id="EEZ40799">
        <property type="protein sequence ID" value="EEZ40799"/>
        <property type="gene ID" value="VDA_001831"/>
    </dbReference>
    <dbReference type="GeneID" id="57342053"/>
    <dbReference type="eggNOG" id="COG0695">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2045232at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097573">
        <property type="term" value="F:glutathione oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004362">
        <property type="term" value="F:glutathione-disulfide reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011767">
        <property type="entry name" value="GLR_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014025">
        <property type="entry name" value="Glutaredoxin_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011902">
        <property type="entry name" value="GRXA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00160">
        <property type="entry name" value="GLUTAREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02183">
        <property type="entry name" value="GRXA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00195">
        <property type="entry name" value="GLUTAREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutaredoxin" evidence="4">
        <location>
            <begin position="3"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="88" mass="10031" checksum="1027D2FA8B5CE713" modified="2010-01-19" version="1">MFVVIFGRPGCPYCVRAKELAEKLKEQRDDFNFRYVDIQAEGISKADLEKTVGKPVETVPQIFIDQEHIGGCTEFEAYAKENLGLFNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX83</accession>
    <name>D0YX83_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">Peptide deformylase</fullName>
            <shortName evidence="4">PDF</shortName>
            <ecNumber evidence="4">3.5.1.88</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3 4">Polypeptide deformylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">def</name>
        <name evidence="5" type="ORF">VDA_001942</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>H2O + N-terminal N-formyl-L-methionyl-[peptide] = formate + N-terminal L-methionyl-[peptide]</text>
            <dbReference type="Rhea" id="RHEA:24420"/>
            <dbReference type="Rhea" id="RHEA-COMP:10639"/>
            <dbReference type="Rhea" id="RHEA-COMP:10640"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:49298"/>
            <dbReference type="ChEBI" id="CHEBI:64731"/>
            <dbReference type="EC" id="3.5.1.88"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="4">Binds 1 Fe(2+) ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the polypeptide deformylase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.88" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298985.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001942"/>
    <dbReference type="EnsemblBacteria" id="EEZ40910">
        <property type="protein sequence ID" value="EEZ40910"/>
        <property type="gene ID" value="VDA_001942"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0242">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1649129at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042586">
        <property type="term" value="F:peptide deformylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00487">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.45.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00163">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023635">
        <property type="entry name" value="Peptide_deformylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036821">
        <property type="entry name" value="Peptide_deformylase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10458">
        <property type="entry name" value="PTHR10458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01327">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004749">
        <property type="entry name" value="Pep_def"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01576">
        <property type="entry name" value="PDEFORMYLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56420">
        <property type="entry name" value="SSF56420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00079">
        <property type="entry name" value="pept_deformyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="4">
        <location>
            <position position="136"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00032756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="171" mass="19344" checksum="A66AB66FD5750DF0" modified="2010-01-19" version="1">MAVLEILTEPNPKLRVQAEDVVDVKAEHIQTLVDDMLQTMYETGNGIGLAAPQVGRKEAIIVIDLSEERNEPQVFINPKIVRGENPVVGQEGCLSVPDYYADVERFEKIAITALDRDGNEINMERDDFLAIALQHEIDHLKGILFIDYLSPLKRQMAMKKVKKYLRSQGIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXG9</accession>
    <name>D0YXG9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 19">Adenosylcobinamide-GDP ribazoletransferase</fullName>
            <ecNumber evidence="7 19">2.7.8.26</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18 19">Cobalamin synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17 19">Cobalamin-5'-phosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="primary">cobS</name>
        <name evidence="20" type="ORF">VDA_001674</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16 19">Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 19">
            <text>adenosylcob(III)inamide-GDP + alpha-ribazole 5'-phosphate = adenosylcob(III)alamin 5'-phosphate + GMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23560"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57918"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:60487"/>
            <dbReference type="ChEBI" id="CHEBI:60493"/>
            <dbReference type="EC" id="2.7.8.26"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 19">
            <text>adenosylcob(III)inamide-GDP + alpha-ribazole = adenosylcob(III)alamin + GMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16049"/>
            <dbReference type="ChEBI" id="CHEBI:10329"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:60487"/>
            <dbReference type="EC" id="2.7.8.26"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 19">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5 19">Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 7/7.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="19">Cell membrane</location>
            <topology evidence="19">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6 19">Belongs to the CobS family.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.26" evidence="7 19"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298495.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001674"/>
    <dbReference type="EnsemblBacteria" id="EEZ40647">
        <property type="protein sequence ID" value="EEZ40647"/>
        <property type="gene ID" value="VDA_001674"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0368">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1996371at2"/>
    <dbReference type="UniPathway" id="UPA00148">
        <property type="reaction ID" value="UER00238"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051073">
        <property type="term" value="F:adenosylcobinamide-GDP ribazoletransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008818">
        <property type="term" value="F:cobalamin 5'-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00719">
        <property type="entry name" value="CobS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003805">
        <property type="entry name" value="CobS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34148">
        <property type="entry name" value="PTHR34148"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02654">
        <property type="entry name" value="CobS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00317">
        <property type="entry name" value="cobS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 19" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10 19" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="13 19" id="KW-0460">Magnesium</keyword>
    <keyword evidence="15 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 19" id="KW-0808">Transferase</keyword>
    <keyword evidence="12 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14 19" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="47"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="150"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="194"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00010561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00015850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00025228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00032605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00032853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="EEZ40647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="267" mass="29547" checksum="F729B4EDE84DB546" modified="2010-01-19" version="1">MKFQFNREQIRYQWQLFLIALSFFTRIPVPQNTPFTEQRLNQANRYFGLVGCIVGLLSALSYLVFAAILPVSIAIGFAMITSMLITGAFHEDGLADVFDGFGGGWTVEKKLSIMKDSRVGTYGLCSLIMMLGLKWLTLTYLAQDSVWLPAYALFVMHGVSRVVAASLIFSYPYVRADQTSKVKPLAKQQSPFELWVLIGTGLVLVSIFPISLAISLIAAMVIVRFAAGAWFQQQLGGYTGDCLGACQQIAELIGYCVILAFYHHILG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXH2</accession>
    <name>D0YXH2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pseudouridine synthase</fullName>
            <ecNumber evidence="3">5.4.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001679</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Responsible for synthesis of pseudouridine from uracil.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a uridine in RNA = a pseudouridine in RNA</text>
            <dbReference type="Rhea" id="RHEA:48348"/>
            <dbReference type="Rhea" id="RHEA-COMP:12068"/>
            <dbReference type="Rhea" id="RHEA-COMP:12069"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pseudouridine synthase RluA family.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001679"/>
    <dbReference type="EnsemblBacteria" id="EEZ40650">
        <property type="protein sequence ID" value="EEZ40650"/>
        <property type="gene ID" value="VDA_001679"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0564">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120159">
        <property type="term" value="F:rRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd02869">
        <property type="entry name" value="PseudoU_synth_RluA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006225">
        <property type="entry name" value="PsdUridine_synth_RluC/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006224">
        <property type="entry name" value="PsdUridine_synth_RluC/D_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00005">
        <property type="entry name" value="rluA_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01129">
        <property type="entry name" value="PSI_RLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S4" evidence="4">
        <location>
            <begin position="49"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR606225-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="344" mass="39363" checksum="A67E22970CC4A7BC" modified="2010-01-19" version="1">MVHSLPLIVFITLPILAELHCFIRLIITLMTEVKPKVQFIEISDDFAGQRIDNFLRARLKNVPKSMIYRILRKGEVRVNKKRIKPEYKLQDGDLVRVPPVSIPEKEDQAPISTNLNKVAELESCIIYEDDHLLVLNKPSGTAVHGGSGLKFGAIEALRALRPDARFLELVHRIDRDTSGILLVAKKRSALRRLQEQFRNKTVQKYYFALVMGEWKASCKKVTAPLLKNEVNSIVRVNPNGKPSDTRFKVLERFHQATLVQASPVTGRTHQIRVHCQYTGHPIAWDDRYGDPRFDAYTKKTGLNRLFLHAANIQFTHPSTDEAMEINAPMEPKLERCLEKLRTMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXK6</accession>
    <name>D0YXK6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PKS_ER domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001720</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298577.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001720"/>
    <dbReference type="EnsemblBacteria" id="EEZ40691">
        <property type="protein sequence ID" value="EEZ40691"/>
        <property type="gene ID" value="VDA_001720"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0604">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1752728at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="11"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="329" mass="35806" checksum="3E77FA28C8C818F2" modified="2010-01-19" version="1">MQSWSLSQPNGLSSLINTNLPPPITKDNEVQIKVHAVGLNPIDYKLTDWGYATWNYPQIIGLDIAGVIEQVGKEISTFKVGDRVFGFLDPRQAGGFAEYVCCKPASLSHIPPHVLYSDAAALPCAGFTAWIALKDKLRLPPNSIIAITGAGGGVGGFAVQLAKIMGLTVYAIAETHHHRRLLGYGADAVIDPNDNVGLKILELTEARLLDAVIDCVSSKTASIMSALIRYNGQLVMIADQFQQIPILATTKAISIHEVALHGTYAHGTLEHIQHLSMVGEQLMTLLENHQLNPMIDKIFPFSELPQGLNYLKQNHHQGKVVVSLIDDLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXM0</accession>
    <name>D0YXM0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001761</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40729">
        <property type="protein sequence ID" value="EEZ40729"/>
        <property type="gene ID" value="VDA_001761"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031NTN">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="39" mass="4595" checksum="8FE4B9415B3719FA" modified="2010-01-19" version="1">MVLKRIETIFDAEPGTPEGDELEKLVTWVEAYEEKHFPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXP5</accession>
    <name>D0YXP5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Valyl-tRNA synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001748</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298619.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001748"/>
    <dbReference type="EnsemblBacteria" id="EEZ40716">
        <property type="protein sequence ID" value="EEZ40716"/>
        <property type="gene ID" value="VDA_001748"/>
    </dbReference>
    <dbReference type="GeneID" id="57342161"/>
    <dbReference type="eggNOG" id="ENOG5031NGF">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1859899at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004812">
        <property type="term" value="F:aminoacyl-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025293">
        <property type="entry name" value="YfiR/HmsC-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13689">
        <property type="entry name" value="DUF4154"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="201" mass="22542" checksum="1EC7CEF950EA4633" modified="2010-01-19" version="1">MQNLRLDKIVLKKQTLRQILADFKTYIRLSARLLLVGCISSIGLVQANTMQVADFKLSAVYIYRFGQFIQWSSQPSSLVYCSLGTDSVAKTLSQLINSNDHHTFISLAHINQIEQCHIVYISPQKESEITQVPIKPQILTVGIGTSFLRKGGMITLQSINQKVRPIIGLEHVSQSGIQISSKLLQIALLYPQDIIEMSEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXQ7</accession>
    <name>D0YXQ7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002070</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299341.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002070"/>
    <dbReference type="EnsemblBacteria" id="EEZ41038">
        <property type="protein sequence ID" value="EEZ41038"/>
        <property type="gene ID" value="VDA_002070"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0697">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1420919at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="149"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="179"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="217"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="247"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="276"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="8"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="149"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="308" mass="34484" checksum="3C0567A10245BD4B" modified="2010-01-19" version="1">MLKIDRAVQYMLLSTLSLSATGLLAKLLSNQLPIPWFSFLRFSMPALILLIVLSFTNIKLPSKQEFKPLLTRALCIGLCQLCFLKSLQTLSLVESVVLFATGPLFMPILERLFFKVRINVWNIAALIVTFVGVILLAGHSGEMKWRFDILLGIAGGIFNAGSQLALYRSSKSTLSPKEINFWCFASAAVFVLPIALFSSSEFHFVSLISSNQGLHQLLFLVMMALLVINTQVNRAKAYKLAHSGSQLAPLIFTNLIFSTIWQFVFFQQTFTHQQIFGLSLIVVATMTNSLLPNWLKKQKVKKPHKKVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXR6</accession>
    <name>D0YXR6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Tail-specific protease</fullName>
            <ecNumber evidence="5">3.4.21.102</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_002079</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S41A family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.102" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299369.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002079"/>
    <dbReference type="MEROPS" id="S41.001"/>
    <dbReference type="EnsemblBacteria" id="EEZ41047">
        <property type="protein sequence ID" value="EEZ41047"/>
        <property type="gene ID" value="VDA_002079"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0793">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1646508at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07560">
        <property type="entry name" value="Peptidase_S41_CPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012530">
        <property type="entry name" value="BAGE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004447">
        <property type="entry name" value="Peptidase_S41A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005151">
        <property type="entry name" value="Tail-specific_protease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020992">
        <property type="entry name" value="Tail_Prtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040573">
        <property type="entry name" value="TSP_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08180">
        <property type="entry name" value="BAGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11818">
        <property type="entry name" value="DUF3340"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00595">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03572">
        <property type="entry name" value="Peptidase_S41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17804">
        <property type="entry name" value="TSP_NTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00245">
        <property type="entry name" value="TSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00225">
        <property type="entry name" value="prc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0720">Serine protease</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019212" evidence="3">
        <location>
            <begin position="23"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="4">
        <location>
            <begin position="238"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="669" mass="75266" checksum="97A63B8F1A05105C" modified="2010-01-19" version="1">MKCRFRFSLIAAGMMLAASAQAVEAKYSSSDLPTLAPEEQHATAAKRVASRLTRSHYKHFNLDDQFSEKMYDRYIEMLDYNRSFLTASDIKQFDKWQDQFDDQLKAGDSVAAYDIFNKTLERRLERYQYALTLLDKPITFTTNEEFVIDRSELPWAKDSNELNEIWRQRVKYDALNLKLAGKDEAEIKKTLTKRYNNALKRLTQTHNEDVFQLYMNAFAREVDPHTSYLSPRNAEQFQSEMNLSLEGIGAVLQMTDDYTVIRSLVAGGPAALSKKLSEGDRIIGVGQKGKKIVDVIGWRLDDVVQLIKGPKGSDVILEILPEGKNSKSYTVTITRDKIRLEDRAAKSEVKTVNGKKIGVIEIPGFYVGLTEDTKKEIAKLNADKVDGVVIDLRNNGGGALTEATALTGLFISEGPVVQVRDSYGRVKVNGDSDNVVYFNGPLTVLINHYSASASEIFAAAMQDYGRAVVLGEQSFGKGTVQQHRSLNHIYDLFDKPLGHVQYTIQKFYRINGGSTQNLGVVPDIAFPTAIDPAETGESVEDNALPWDSIKPADYKKIYNFSPVVPKLEAEHKARIKNDMEFGFIAEDIKQYKAEKDVNTISLNEKTRIKEQDKDDADRLARLNKRQKVLGKPAFKSLDDVPKDYEAPDVYLDEAVAITSDLVKEKVKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXX1</accession>
    <name>D0YXX1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002134</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299514.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002134"/>
    <dbReference type="EnsemblBacteria" id="EEZ41102">
        <property type="protein sequence ID" value="EEZ41102"/>
        <property type="gene ID" value="VDA_002134"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0790">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019829" evidence="1">
        <location>
            <begin position="25"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="324" mass="36692" checksum="9EA2228A14F69511" modified="2010-01-19" version="1">MEKIKIGYWWLLCLCLLFVSQIQAQATYPAPNTMSVEDAYQLGDLLVDQYKIKQGQPYLKYAADKGNAKAALAYSRSLSTNVMVLGPQEHEYAVKAAKLGSDDAKFALSFSRNVFGDRDLYRAEQIKALKDRAKQGDAKAMYRLSLLYSGSEETEWKEKAAEHGDANAQYELGRTYEVGDGWFFIPGKREKEVKRLYKASAEQGNFRGMEGYASILLREGKKEKALEIWKKMANTGDAGSIIFLAAGYLNATPRITYPEKDEVLGAAYSKIYLDSMGTDKKQSLYEIYKEDYLEAMSHLSEAQKEQVNDFAKEFLKTHTVRVLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXY1</accession>
    <name>D0YXY1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uropathogenic specific protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002144</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002144"/>
    <dbReference type="EnsemblBacteria" id="EEZ41112">
        <property type="protein sequence ID" value="EEZ41112"/>
        <property type="gene ID" value="VDA_002144"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4104">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008727">
        <property type="entry name" value="PAAR_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05488">
        <property type="entry name" value="PAAR_motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="65" mass="6468" checksum="A6FDAF178C80B19C" modified="2010-01-19" version="1">MIDGKPAARQGDALAPHAKPKHPPHPRAISQGSGSVFIDGKPAARSGDAIDCGGKVQASGTVNIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY22</accession>
    <name>D0YY22_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002185</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299608.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41153">
        <property type="protein sequence ID" value="EEZ41153"/>
        <property type="gene ID" value="VDA_002185"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5032YUC">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1895890at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="105" mass="11740" checksum="49A31A2D4E04A194" modified="2010-01-19" version="1">MDFFVPSATSTEQAEAVFSSIAQHVSAPSQAKRIHKIVWNHEGEKCQCIVGEKLPEIFRAEEKVLAIFDCGDVFKICTPNRGAIKFDPIHASRSAVVDLEFFDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY23</accession>
    <name>D0YY23_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA polymerase</fullName>
            <ecNumber evidence="5">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_002186</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the DNA polymerase type-B family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002186"/>
    <dbReference type="EnsemblBacteria" id="EEZ41154">
        <property type="protein sequence ID" value="EEZ41154"/>
        <property type="gene ID" value="VDA_002186"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0417">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1600.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006172">
        <property type="entry name" value="DNA-dir_DNA_pol_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017964">
        <property type="entry name" value="DNA-dir_DNA_pol_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006133">
        <property type="entry name" value="DNA-dir_DNA_pol_B_exonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006134">
        <property type="entry name" value="DNA-dir_DNA_pol_B_multi_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042087">
        <property type="entry name" value="DNA_pol_B_thumb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023211">
        <property type="entry name" value="DNA_pol_palm_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00136">
        <property type="entry name" value="DNA_pol_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03104">
        <property type="entry name" value="DNA_pol_B_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00106">
        <property type="entry name" value="DNAPOLB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00486">
        <property type="entry name" value="POLBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00116">
        <property type="entry name" value="DNA_POLYMERASE_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0235">DNA replication</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 5" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="3 5 8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA_pol_B_exo1" evidence="7">
        <location>
            <begin position="94"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="DNA_pol_B" evidence="6">
        <location>
            <begin position="392"/>
            <end position="773"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ41154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="801" mass="92623" checksum="C52D960856E07632" modified="2010-01-19" version="1">MYKNTVEVRLQVHQTGFVLTRQGRDSHDQTDITLWVNTAQGPCRLNIKGESPICFIATENEQTAAQLLRQHNELVSWRQLGLKTFNHTSVSVCYCKTIKQLSRVIELLNRNDIITYEDDIRLADRYLMERFIRGGLHFTGTAKQRKGFIDYYDVKTKSADFQPDLNLVSLDIECSEKGVLYSVGLHSKADSRVIMVGEPQHLIDQTTPIYWVRDESQLLMALVDWFHEFDPDIVIGWNVIDFDFRLLLQRAEWNKVPFKIGRGQQNAHYRQSNQNRNQGFLTIPGRVVLDGIDTLKTATYNFRSWSLEAVSQELLGEGKQIHNVHDRMAEINEMFRHNKQALAKYNLQDCKLVTRIFEQTHSLDFAIERSRLTGVELDRVGGSVAAFTNLYLPQLHRAGYIAPNLATDNWIASPGGYVMDSKPGLYDSVLVLDFKSLYPSIIRSFRIDPMGLVEGLLLVEGKEHDRAIAGFRGGRFHREKHFLPKMIEDLWSARDQAKREGEKAFSQAIKIIMNSFYGVLGSSGCRFFDHRLASSITMRGHEIMKKTRELIELKGYEVIYGDTDSTFVSLTQAHSQQDADKIGHELVAYINQWWTEHLLNDYGLDSALEIEYETHYHKFLMPTIRGQETGSKKRYAGLVWRGNNEEMIFKGLETVRTDWTPLAQEFQQTLYKMIFHDQNPDEYIRDYTQRTSLGEFDDLLIYRKRLRRNLDEYQKNIPPQVKAARMADEINRRLGRPLQYQNKGIIEYVITLAGAEASEYRQNPIDYQHYIDKQLKPVADAILPFIGKQFDDITAAQLGLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY92</accession>
    <name>D0YY92_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002255</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002255"/>
    <dbReference type="EnsemblBacteria" id="EEZ41223">
        <property type="protein sequence ID" value="EEZ41223"/>
        <property type="gene ID" value="VDA_002255"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1376">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032676">
        <property type="entry name" value="YkuD_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38477">
        <property type="entry name" value="PTHR38477"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13645">
        <property type="entry name" value="YkuD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019881" evidence="1">
        <location>
            <begin position="22"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="216" mass="24328" checksum="E9228C2264AB8D55" modified="2010-01-19" version="1">MKKALALFLLMFSYMPLQAYASNVVHHHSYTERKNSDIVVEYVYEKAKLNGIVDYEAFKKGFNAYNKIKGKKKSLLTIIDYSKPSNEKRFYVIDLKRNKLLYKTYVAHGVNSGLLMAKNFSNTVDSHKTSLGTYLTATTYNGSNGYSLKLQGLTRGKNTNALKRYIVIHGAKYATEAFIKHNGYLGRSWGCPALPPQLARKIIDTIKGGSVIFAYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYC1</accession>
    <name>D0YYC1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002284</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299786.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41252">
        <property type="protein sequence ID" value="EEZ41252"/>
        <property type="gene ID" value="VDA_002284"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502ZB2S">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1012952at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="433" mass="49844" checksum="C1CC7C301BC9D161" modified="2010-01-19" version="1">MASPLSDLDELVIKCRDKQAQNYIKEAVSCYKAGAFRSAIVSTWIAVSFDIIEKLKDLTLQGDKEAEIHLNAFDDARTKGDISRSLKFEREILAICRDKLELISHVEFIDLDRLQEDRNRCAHPSMTHDGELFSPSAELARIHIRSAVEHLLQYPPSQGKAALESLILLVESSYFPNDIDKAVVAFENSPFRRARKSLVSNFATVVLKKYIGEPEYKKRLSYSVALNAINELYREEFSEVLASKLSNLLRRLEDKELYKSLYVFEQIPESWEFIDVDVQHKVETYIENLPKERLDFWEFLLVHDKLSVPAQKRLSKANRSELDEPLFFTPPEAFLERVIELYASSGSFEQANTFATTVIRYAGDYSYSQVNRIVLGCGKNDQIEYSFEIGNVINALRRNKFVDDEQINNWLKEANLPKYVREKAVEEVAEEDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-02-10" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYT8</accession>
    <name>D0YYT8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Zn_protease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002451</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002451"/>
    <dbReference type="EnsemblBacteria" id="EEZ41419">
        <property type="protein sequence ID" value="EEZ41419"/>
        <property type="gene ID" value="VDA_002451"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4067">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008503">
        <property type="entry name" value="Put_Zn_protease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05618">
        <property type="entry name" value="Zn_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="SSF50630"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn_protease" evidence="2">
        <location>
            <begin position="65"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="5"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="220" mass="25042" checksum="161E3440A238E426" modified="2010-01-19" version="1">MSQHIDQQNQHIAKLESKLANISKDVKFVKHKSLTEPKLIVEKQIVRVPVEEKKVDPKVANGKVVLGQEEWVWIDSIKAHFKARVDTGATTSSINAQDIQTFERDGKEWIRFNLTHQGEDNTDEKAQAAKVDEIEAPVVRWVKIRQASTEEAVRRPVVELWVQLGSLHEKAQFTLADRSQMDYPVLLGREFFKDIALVDVGKKYIQGKTEPKPEPAAVTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYU3</accession>
    <name>D0YYU3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Aldehyde-alcohol dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_002456</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the N-terminal section; belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300127.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002456"/>
    <dbReference type="EnsemblBacteria" id="EEZ41424">
        <property type="protein sequence ID" value="EEZ41424"/>
        <property type="gene ID" value="VDA_002456"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1012">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1454">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1456634at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008774">
        <property type="term" value="F:acetaldehyde dehydrogenase (acetylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004022">
        <property type="term" value="F:alcohol dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006066">
        <property type="term" value="P:alcohol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015976">
        <property type="term" value="P:carbon utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08178">
        <property type="entry name" value="AAD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034789">
        <property type="entry name" value="AAD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001670">
        <property type="entry name" value="ADH_Fe/GldA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018211">
        <property type="entry name" value="ADH_Fe_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039697">
        <property type="entry name" value="Alcohol_dehydrogenase_Fe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012079">
        <property type="entry name" value="Bifunc_Ald-ADH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11496">
        <property type="entry name" value="PTHR11496"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00465">
        <property type="entry name" value="Fe-ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000111">
        <property type="entry name" value="ALDH_ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00913">
        <property type="entry name" value="ADH_IRON_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00060">
        <property type="entry name" value="ADH_IRON_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="4">
        <location>
            <begin position="4"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="Fe-ADH" evidence="5">
        <location>
            <begin position="457"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="877"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="882"/>
            <end position="897"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR000111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="897" mass="97102" checksum="B54AEF1B10542CA4" modified="2010-01-19" version="1">MPVTNMAELDAMIARVKAAQKEFATFSQEQVDKIFRAASLAANNARIPLAQQAVAESGMGIVEDKVIKNHFASEFIYNKYKDEKTCGILEVNDEFGTMTIAEPVGIICGIVPTTNPTSTAIFKSLISLKTRNAIIFSPHPRAKESTNAAAKLVLDAAVAAGAPKDIIGWIDQPSVELSNALMKHDDINLILATGGPGMVKAAYSSGKPAIGVGAGNVPVVIDETADVKRAVASVLMSKTFDNGVVCASEQAVIVMDEVYDEVKERFASHNGYVLTKEEADKVRKVLLINGALNADIVGQPAVKIAEMAGVKVPAATKILIGEGLQVSADDEFAHEKLSPTLGMFRATSFENAVDQAVTMVEIGGIGHTSGLYTNQDVNADRIKYFGDRLKTARILVNIPTTHGGIGDLYNFNVAPSLTLGCGSWGGNSISENVGPKHLINKKTVAKRAENMLWHKLPKSIYFRRGSLPIALSDLEGKKRAFLVTDRFLFNNGYADEIVALLKAQGMEVQTFFDVEADPTLSVVEKGAEMMKSFQPDVILALGGGSPMDAAKIMWVMYEHPETCFEDLAMRFMDIRKRIFKFPKMGQKAELVCITTTSGTGSEVTPFAVVTDDKTGAKYPLADYELTPNMAIVDANLVMNMPKSLTAFGGYDAVTHALEAYVSVLANEYSDGQALQALKMLKEYLPSSYANGAKDPIAREKVHNAATIAGIAFANAFLGVCHSMAHKLGAEFHIPHGLANALLISNVVRYNANDNPTKQTAFSQYDRPQARRRYAEVADHLGLSQPGDRTAQKIERLLTWLDELKVNLEIPMSIQAAGVPEADFLAKLDELSVEAFDDQCTGANPRYPLIAELKDVLLASYYGKAFVEGETFEGTTVIKKSEPLTEKPAKTKKEKAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ73</accession>
    <name>D0YZ73_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chemotaxis regulator CheY</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002586</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002586"/>
    <dbReference type="EnsemblBacteria" id="EEZ41554">
        <property type="protein sequence ID" value="EEZ41554"/>
        <property type="gene ID" value="VDA_002586"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="44" mass="4952" checksum="734C5B1124CD6CB4" modified="2010-01-19" version="1">MITAEAKREQIIEAAQAGVNGYIVKPFTAATLIEKLEKIFERMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ87</accession>
    <name>D0YZ87_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 12">Flagellar M-ring protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">VDA_002600</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 12">The M ring may be actively involved in energy transduction.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The M ring is integral to the inner membrane of the cell and may be connected to the flagellar rod via the S ring. The S (supramembrane ring) lies just distal to the M ring. The L and P rings lie in the outer membrane and the periplasmic space, respectively.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 12">Bacterial flagellum basal body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 12">Belongs to the FliF family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300444.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002600"/>
    <dbReference type="EnsemblBacteria" id="EEZ41568">
        <property type="protein sequence ID" value="EEZ41568"/>
        <property type="gene ID" value="VDA_002600"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1766">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="167675at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009431">
        <property type="term" value="C:bacterial-type flagellum basal body, MS ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003774">
        <property type="term" value="F:cytoskeletal motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013556">
        <property type="entry name" value="Flag_M-ring_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000067">
        <property type="entry name" value="FlgMring_FliF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006182">
        <property type="entry name" value="FliF_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043427">
        <property type="entry name" value="YscJ/FliF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30046">
        <property type="entry name" value="PTHR30046"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30046:SF0">
        <property type="entry name" value="PTHR30046:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01514">
        <property type="entry name" value="YscJ_FliF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08345">
        <property type="entry name" value="YscJ_FliF_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004862">
        <property type="entry name" value="FliF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01009">
        <property type="entry name" value="FLGMRINGFLIF"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00206">
        <property type="entry name" value="fliF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="17" id="KW-0966">Cell projection</keyword>
    <keyword evidence="17" id="KW-0969">Cilium</keyword>
    <keyword evidence="17" id="KW-0282">Flagellum</keyword>
    <keyword evidence="9 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="48"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="470"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="domain" description="YscJ_FliF" evidence="15">
        <location>
            <begin position="73"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="YscJ_FliF_C" evidence="16">
        <location>
            <begin position="278"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="239"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00025936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR004862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF01514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF08345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EEZ41568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="581" mass="63792" checksum="5B6A5B219EF9F843" modified="2010-01-19" version="1">MSDSLSNQELLPGNNGQAALISSNDTADTDLGEKKASKSDSILGNLDLLRQVILVLAVAICVSLIIMVMMWIKEPEMRPLGNYETSELITVLDALDQKKIEYQLDGNTIRVPADQYSAIKLTLARDGWSAPEAQGDDILLKNMGFGVSQRLEQERLKLSRERQLARAIEQIKQVRKAQVLLALPKQSVFVRNNQDASATVFLTLSSGATLGQQEVDSIVDMVASAVPGLKPTRVTVTDQHGRLLSSGTEDPSATAKRKEYELERKQEQTLREKIDAILMPILGLGNYTSQVDVSMDFSSLEETQKQFDPSKPATRSEFILEDLNNSNRVGGIPGALSNQPPADSAIPQDVKDLQSGKSLSDGSVHREETRNYELDTTIRHKRSQTGTIARQTVSVAVDYKNITDPKTGKVTRVPVSDAELEKIRRLLMGGVGFSQARGDLLEVISMPFALPEELALANPPIWENPNFSSWIRWIAAALVIIVMIIVLIRPAMRKLLYPNQTAEGIPLDENGVPMLNHHGDGITLIGSDLDAGDSLELSTSQLELPSLHRDEDLLKAVRALVANEPDLAAQVIKNWMSENGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ93</accession>
    <name>D0YZ93_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Lysine-N-methylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002606</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300466.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002606"/>
    <dbReference type="EnsemblBacteria" id="EEZ41574">
        <property type="protein sequence ID" value="EEZ41574"/>
        <property type="gene ID" value="VDA_002606"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0727">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1674644at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="396" mass="45858" checksum="FE139F3FB18FF311" modified="2010-01-19" version="1">MKFIEAIPQFVDNFSCIADKCENHCCHGWNINIDKTTYKFMVHKSTFKGRSKKWIERIPNQSASSAYARIKLNDQGVCPFRDQQGLCEVHKHHGHACLSDTCKIYPRLTFTRGDRVEQLLSLSCPEAARQILFNPEAMLCREQEIESDFAAKSYERPFYYDVLRQLYIDILLIDSVPMEARLFILGMTLKLLEARKDDRDEFEKCYQVCIEQITNGDFLSTYTQSTTAESFHPGFLIRAFNAHLYIGVKSQYSSVIEQLKKIHNNLLAALEPAGDDVQQQVDILQQGFNGHYSSFIAEYPQLWINYFLYGMHFYDFPKDDWYQAYSNLVIDFVIIRGILMAIASQRELTHQDVIDVVHTFHRARSHGIHLSGSIKNIIENGLQVDEKVLPLMLLKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZI6</accession>
    <name>D0YZI6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ancillary SecYEG translocon subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_002699</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the YfgM family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002699"/>
    <dbReference type="EnsemblBacteria" id="EEZ41667">
        <property type="protein sequence ID" value="EEZ41667"/>
        <property type="gene ID" value="VDA_002699"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2976">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044877">
        <property type="term" value="F:protein-containing complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018704">
        <property type="entry name" value="TPR_21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026039">
        <property type="entry name" value="YfgM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38035">
        <property type="entry name" value="PTHR38035"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09976">
        <property type="entry name" value="TPR_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TPR_21" evidence="4">
        <location>
            <begin position="9"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00024197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF09976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="144" mass="15667" checksum="F88841C6E83E52B4" modified="2010-01-19" version="1">MAMLESGKSDAIADTQAFIQAHKDSHYSVLAALQLAKAQIEAKDLNGAAEQLKWVAANSTDQAILPLAKTRLARVYLQQDKYDEALAELKTVKMASWKAKVDELRGDVLLKKGDTDAARDAYIEAQEAGANSPVLQIKLDNLAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZI9</accession>
    <name>D0YZI9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hypothetical DNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_002702</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300742.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002702"/>
    <dbReference type="EnsemblBacteria" id="EEZ41670">
        <property type="protein sequence ID" value="EEZ41670"/>
        <property type="gene ID" value="VDA_002702"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1426">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2071222at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025194">
        <property type="entry name" value="DUF4115"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13464">
        <property type="entry name" value="DUF4115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="114"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="HTH cro/C1-type" evidence="3">
        <location>
            <begin position="21"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="327" mass="35692" checksum="9AB8F934669A05C4" modified="2010-01-19" version="1">MNREQNEERQAEIAQTPGEMLRAAREQLGYSQKDIANRLRLRLSVINDIEDNRFEQAQLATFTRGYVRSYAKYVGVDEKSILALLDQYGHAQPQEQEMQSFSRRTKREAHDSRIMGLTWILAAVFLGLTAVWWWQSLQVQPSTHKESTVKAEVSAPANEKDSNYVSTLEENGAATVTKADTSPSSAAVAQPESANTSSQSNTSAASETAASSEPATSNQSIANQADTSATEAKPVDVQTPAAEETVAVVPDLQLTFSGDCWIDIKDANGKRLETGIKKAGDKLDLDGKAPFKIVLGAPGVVKMNYQGQPVDLSKYPAGRVARFKLPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZQ0</accession>
    <name>D0YZQ0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lipopolysaccharide N-acetylglucosaminyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002763</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300934.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002763"/>
    <dbReference type="EnsemblBacteria" id="EEZ41731">
        <property type="protein sequence ID" value="EEZ41731"/>
        <property type="gene ID" value="VDA_002763"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="694191at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="14"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="227"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="401" mass="45007" checksum="5D14364B134145AB" modified="2010-01-19" version="1">MKVLFVNKFFFPHGGAETVFFQEREMVQEAGYQVIDFSMKHEKNIPSEQSEYFVENVDYHGKHSIFDSLKVAINFVHNKDACEQFEKLIKAEKPDIVHFHNIYHQITPSVIKVAQKHGCKTVLTAHDYKSVCPNYSMLAAGESIDLDWISGSNINLFKYQWQDGSWPRSILLSLEALYHRVMKSYEALDTFIAPCDFMKSMILRQIPSANVEVIVNGIDASATEVGDDGGYFLFCGRLTQEKGVVTLAEAHKKLTGDTPLKVLGTGPMFDYLKDNFDNVELLGFQTGETLTNIIKNAKAVIVPSEWNENCSMSVLEAMSYGKPVIGANIGGIPEQILDGETGYLFKSGDANDLASKMQALADNSELVTDMGLKARSRLLEKYSLDVHKRELIKLYQSLLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZY8</accession>
    <name>D0YZY8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Probable lipid II flippase MurJ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">murJ</name>
        <name evidence="10" type="ORF">VDA_002851</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 9">Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell inner membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8 9">Belongs to the MurJ/MviN family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002851"/>
    <dbReference type="EnsemblBacteria" id="EEZ41819">
        <property type="protein sequence ID" value="EEZ41819"/>
        <property type="gene ID" value="VDA_002851"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0728">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015648">
        <property type="term" value="F:lipid-linked peptidoglycan transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13123">
        <property type="entry name" value="MATE_MurJ_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02078">
        <property type="entry name" value="MurJ_MviN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004268">
        <property type="entry name" value="MurJ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03023">
        <property type="entry name" value="MurJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002869">
        <property type="entry name" value="MviN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01806">
        <property type="entry name" value="VIRFACTRMVIN"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01695">
        <property type="entry name" value="murJ_mviN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="2 8 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 8 9" id="KW-0133">Cell shape</keyword>
    <keyword evidence="8 9" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7 8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 8 9" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="93"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="138"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="166"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="199"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="256"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="283"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="322"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="359"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="392"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="416"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="450"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="487"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR002869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ41819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="519" mass="56683" checksum="8A98C52FC116ED19" modified="2010-01-19" version="1">MSKRLLRSGMIVSAMTLVSRVLGLVRDVVVANLMGAGAAADVFFFANKIPNFLRRLFAEGAFSQAFVPVLTEYHASGDMDKTRQLIAKASGTLGAIVTLVTIVGVLGSGVVTALFGFGWFLDWLHGGPAAEKFELASLLLKITFPYLWFITFVALSGAILNTLGKFAISSFTPVFLNVAIISCAAFLSPKLAQPEIGLAVGVFLGGMIQFAFQLPFLYREGFLVRPQWGWNDPGVVKIRKLMLPALFGVSVSQINLLLDTFIASFLMTGSISWLYYSDRLLEFPLGMFGIAIATVILPALSRKHVEQSGNQFAETMDWGVRMVLLLGIPAMLGMIVLAKPMLMVLFMRGEFNVYDVNQTAMSLWAMSAGLLNFMLIKVLAPGYYARQDTKTPVKIGIIAMVSNMVFNAMFAPFFGYVGLAIATALSALVNASLLYRGLHKGNVYRVSRKTLWFVARLVVAGGIMVGTLLYIMPPMAQWVDWSTAHRALWLASLIGLGGVVYVLIALILGVRFHHLRTDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z002</accession>
    <name>D0Z002_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptide chain release factor 2</fullName>
            <shortName evidence="4">RF-2</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">prfB</name>
        <name evidence="7" type="ORF">VDA_002865</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="4">Methylated by PrmC. Methylation increases the termination efficiency of RF2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the prokaryotic/mitochondrial release factor family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002865"/>
    <dbReference type="EnsemblBacteria" id="EEZ41833">
        <property type="protein sequence ID" value="EEZ41833"/>
        <property type="gene ID" value="VDA_002865"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1186">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016149">
        <property type="term" value="F:translation release factor activity, codon specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00094">
        <property type="entry name" value="Rel_fac_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005139">
        <property type="entry name" value="PCRF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000352">
        <property type="entry name" value="Pep_chain_release_fac_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045853">
        <property type="entry name" value="Pep_chain_release_fac_I_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004374">
        <property type="entry name" value="PrfB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03462">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00472">
        <property type="entry name" value="RF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00937">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75620">
        <property type="entry name" value="SSF75620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00020">
        <property type="entry name" value="prfB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00745">
        <property type="entry name" value="RF_PROK_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0488">Methylation</keyword>
    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RF_PROK_I" evidence="6">
        <location>
            <begin position="227"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="263"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="modified residue" description="N5-methylglutamine" evidence="4">
        <location>
            <position position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="347" mass="38856" checksum="C5B30DAB6BF059A0" modified="2010-01-19" version="1">MSLGGIFDYDAKKERLEEVNAELEQPDVWNEPERAQALGKERASLEAVVETIDQLDQGVDDVEGLLELAVEAEDQETFDEIEPELAELEAKLAKLEFRRMFSGDHDGSDCYLDLQAGSGGTEAQDWTSMMLRMYLRWADAKGFKTEVIEVSEGDVAGLKSATIRISGEYAYGWLRTETGVHRLVRKSPFDSGGRRHTSFASAFVYPEVDDNIDIDINPSDLRIDVYRASGAGGQHVNTTESAVRITHIPTNTVVQCQNDRSQHKNKDQAMKQLKAKLFELEMQKQNAEKQANEDSKSDIGWGSQIRSYVLDDSRIKDLRTGVENRNTQAVLDGDLDRFIEASLKSGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z065</accession>
    <name>D0Z065_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Ornithine carbamoyltransferase</fullName>
            <shortName evidence="5">OTCase</shortName>
            <ecNumber evidence="3 5">2.1.3.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_002928</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>carbamoyl phosphate + L-ornithine = H(+) + L-citrulline + phosphate</text>
            <dbReference type="Rhea" id="RHEA:19513"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="EC" id="2.1.3.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.3.3" evidence="3 5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301373.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002928"/>
    <dbReference type="EnsemblBacteria" id="EEZ41896">
        <property type="protein sequence ID" value="EEZ41896"/>
        <property type="gene ID" value="VDA_002928"/>
    </dbReference>
    <dbReference type="GeneID" id="57340768"/>
    <dbReference type="eggNOG" id="COG0078">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="988597at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016597">
        <property type="term" value="F:amino acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004585">
        <property type="term" value="F:ornithine carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1370">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01109">
        <property type="entry name" value="OTCase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006132">
        <property type="entry name" value="Asp/Orn_carbamoyltranf_P-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006130">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036901">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006131">
        <property type="entry name" value="Asp_carbamoyltransf_Asp/Orn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002292">
        <property type="entry name" value="Orn/put_carbamltrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024904">
        <property type="entry name" value="OTCase_ArgI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00185">
        <property type="entry name" value="OTCace"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02729">
        <property type="entry name" value="OTCace_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00100">
        <property type="entry name" value="AOTCASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00102">
        <property type="entry name" value="OTCASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53671">
        <property type="entry name" value="SSF53671"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00658">
        <property type="entry name" value="orni_carb_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00097">
        <property type="entry name" value="CARBAMOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="OTCace_N" evidence="8">
        <location>
            <begin position="8"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="OTCace" evidence="7">
        <location>
            <begin position="157"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Carbamoyl phosphate binding" evidence="5">
        <location>
            <begin position="57"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Carbamoyl phosphate binding" evidence="5">
        <location>
            <begin position="135"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Ornithine binding" evidence="5">
        <location>
            <begin position="237"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Carbamoyl phosphate binding" evidence="5">
        <location>
            <begin position="275"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>carbamoyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>carbamoyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>L-ornithine</name>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>L-ornithine</name>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="322"/>
        </location>
        <ligand>
            <name>carbamoyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="336" mass="37598" checksum="0BD3A878731EEF93" modified="2010-01-19" version="1">MAFNLRNRNFLKLLDFTPREIQHLLELSAELKKAKYNGYEQPRLTGKNIALIFEKTSTRTRCAFEVAAFDQGAQVSYLGPSGSQIGHKESMKDTARVLGRMYDGIEYRGFGQDIVEELGKYAGVPVWNGLTDEFHPTQILADFLTMQEHARGKQLHEITFAYLGDARNNMGNSLMVGAAKMGMDIRLVAPKAFWPEEQLVAQCRAIAAETGAKITMTEDVQEGVQGCDFLYTDVWVSMGEAKEAWAERINLMLPYQVNMDVIKATGNPHVKFMHCLPAFHGEDTTVGKELAKEYPVLAKGVEVTDEVIESDYSIVFDEAENRMHTIKAVMVATLGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z088</accession>
    <name>D0Z088_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">tRNA N6-adenosine threonylcarbamoyltransferase</fullName>
            <ecNumber evidence="6">2.3.1.234</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">N6-L-threonylcarbamoyladenine synthase</fullName>
            <shortName evidence="6">t(6)A synthase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">tRNA threonylcarbamoyladenosine biosynthesis protein TsaD</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">tsaD</name>
        <name evidence="8" type="ORF">VDA_002951</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>adenosine(37) in tRNA + L-threonylcarbamoyladenylate = AMP + H(+) + N(6)-L-threonylcarbamoyladenosine(37) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:37059"/>
            <dbReference type="Rhea" id="RHEA-COMP:10162"/>
            <dbReference type="Rhea" id="RHEA-COMP:10163"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:73682"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74418"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.3.1.234"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="6">Binds 1 Fe(2+) ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the KAE1 / TsaD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.234" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301409.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002951"/>
    <dbReference type="EnsemblBacteria" id="EEZ41919">
        <property type="protein sequence ID" value="EEZ41919"/>
        <property type="gene ID" value="VDA_002951"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0533">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1257362at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061711">
        <property type="term" value="F:N(6)-L-threonylcarbamoyladenine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002949">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01445">
        <property type="entry name" value="TsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000905">
        <property type="entry name" value="Gcp-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017861">
        <property type="entry name" value="KAE1/TsaD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017860">
        <property type="entry name" value="Peptidase_M22_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022450">
        <property type="entry name" value="TsaD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735">
        <property type="entry name" value="PTHR11735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735:SF6">
        <property type="entry name" value="PTHR11735:SF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00814">
        <property type="entry name" value="TsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00789">
        <property type="entry name" value="OSIALOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00329">
        <property type="entry name" value="gcp_kae1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03723">
        <property type="entry name" value="T6A_TsaD_YgjD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01016">
        <property type="entry name" value="GLYCOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 6" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TsaD" evidence="7">
        <location>
            <begin position="24"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="134"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="272"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="300"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ41919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="339" mass="36628" checksum="16A52AEF7E51202A" modified="2010-01-19" version="1">MRILGIETSCDETGIAIFDDEKGLLAHELYSQVKLHADYGGVVPELASRDHVKKTIPLVKAALKSAGLTPADLDGVAYTAGPGLVGALLVGATIGRSLAYAWDLPAVAVHHMEGHLLAPMLEENAPEFPFVALLVSGGHTMMVEVKGIGEYQILGESIDDAAGEAFDKTAKLMGLDYPGGPLLSKMAENGTPGRFTFPRPMTDRPGLDFSFSGLKTFAANTIRSNGDDEQTRADIAFAFQEAVVDTLAIKCKRALKQTGLKRLVIAGGVSANKYLRQELEKLMKGMKGEVFYPRTEFCTDNGAMIAYAGMQRLKNKELMDLGVKAFPRWPIDQLKPIDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0A6</accession>
    <name>D0Z0A6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Thiamin ABC transporter ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_002969</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301437.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002969"/>
    <dbReference type="EnsemblBacteria" id="EEZ41937">
        <property type="protein sequence ID" value="EEZ41937"/>
        <property type="gene ID" value="VDA_002969"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3840">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1200451at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048502">
        <property type="term" value="F:ABC-type thiamine transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005968">
        <property type="entry name" value="Thiamine_ABC_ThiQ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01277">
        <property type="entry name" value="thiQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="33"/>
            <end position="40"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="234" mass="25756" checksum="022A82E5D13F2A40" modified="2010-01-19" version="1">MLKLEQVRYHYENGETMMFNLQAQDGEIVAILGPSGAGKSTLMALISGFLTPQSGQIMFNGQVLNQLKPAQRPLSILFQEHNLFPHLTVFANIGLGLNGKLHLSDAQRDTITQVAAQVGLDSFLDRLPPSLSGGQKQRVALARCLARQRPLLLLDEPFSALDPILRQEMLNQVKQLAKEQHITVLMITHNPDDALLISDKCAFVSGGEVVEFGSTQALFHAPAHPELQRYLGLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0C4</accession>
    <name>D0Z0C4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">Arginine repressor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">argR</name>
        <name evidence="14" type="ORF">VDA_002987</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Regulates arginine biosynthesis genes.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Amino-acid biosynthesis; L-arginine biosynthesis [regulation].</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the ArgR family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301489.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002987"/>
    <dbReference type="EnsemblBacteria" id="EEZ41955">
        <property type="protein sequence ID" value="EEZ41955"/>
        <property type="gene ID" value="VDA_002987"/>
    </dbReference>
    <dbReference type="GeneID" id="57340700"/>
    <dbReference type="eggNOG" id="COG1438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1640037at2"/>
    <dbReference type="UniPathway" id="UPA00068"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034618">
        <property type="term" value="F:arginine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051259">
        <property type="term" value="P:protein complex oligomerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00173">
        <property type="entry name" value="Arg_repressor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001669">
        <property type="entry name" value="Arg_repress"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020899">
        <property type="entry name" value="Arg_repress_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036251">
        <property type="entry name" value="Arg_repress_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020900">
        <property type="entry name" value="Arg_repress_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34471">
        <property type="entry name" value="PTHR34471"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01316">
        <property type="entry name" value="Arg_repressor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02863">
        <property type="entry name" value="Arg_repressor_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01467">
        <property type="entry name" value="ARGREPRESSOR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55252">
        <property type="entry name" value="SSF55252"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01529">
        <property type="entry name" value="argR_whole"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 11" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="5 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0678">Repressor</keyword>
    <keyword evidence="10 11" id="KW-0804">Transcription</keyword>
    <keyword evidence="8 11" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Arg_repressor" evidence="12">
        <location>
            <begin position="6"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="domain" description="Arg_repressor_C" evidence="13">
        <location>
            <begin position="82"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEZ41955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="156" mass="17100" checksum="155DA43DCF229A42" modified="2010-01-19" version="1">MRNSDKQERLVRAFKAILKEEKFSSQGEIVDALKAQGFDNINQSKVSRMLTKFGAVRTRNAKMEMVYCLPIELGVPTTTSPLKELVMEVGYNSALVVIHTGPGAAQVIARLLDSLGKAEGILGVVAGDDTIFITPTNSTTTEELYDSVCELFEYAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0E6</accession>
    <name>D0Z0E6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphoadenosine 5'-phosphosulfate reductase</fullName>
            <shortName evidence="3">PAPS reductase</shortName>
            <ecNumber evidence="3">1.8.4.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">3'-phosphoadenylylsulfate reductase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">PAPS reductase, thioredoxin dependent</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">PAPS sulfotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">PAdoPS reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">cysH</name>
        <name evidence="5" type="ORF">VDA_003010</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>[thioredoxin]-disulfide + adenosine 3',5'-bisphosphate + 2 H(+) + sulfite = 3'-phosphoadenylyl sulfate + [thioredoxin]-dithiol</text>
            <dbReference type="Rhea" id="RHEA:11724"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17359"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:58339"/>
            <dbReference type="ChEBI" id="CHEBI:58343"/>
            <dbReference type="EC" id="1.8.4.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the PAPS reductase family. CysH subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.8" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301556.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003010"/>
    <dbReference type="EnsemblBacteria" id="EEZ41977">
        <property type="protein sequence ID" value="EEZ41977"/>
        <property type="gene ID" value="VDA_003010"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="674332at2"/>
    <dbReference type="UniPathway" id="UPA00140">
        <property type="reaction ID" value="UER00206"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004604">
        <property type="term" value="F:phosphoadenylyl-sulfate reductase (thioredoxin) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070814">
        <property type="term" value="P:hydrogen sulfide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019379">
        <property type="term" value="P:sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01713">
        <property type="entry name" value="PAPS_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00063">
        <property type="entry name" value="CysH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004511">
        <property type="entry name" value="PAPS/APS_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002500">
        <property type="entry name" value="PAPS_reduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011800">
        <property type="entry name" value="PAPS_reductase_CysH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01507">
        <property type="entry name" value="PAPS_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000857">
        <property type="entry name" value="PAPS_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00434">
        <property type="entry name" value="cysH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02057">
        <property type="entry name" value="PAPS_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAPS_reduct" evidence="4">
        <location>
            <begin position="51"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; cysteine thiosulfonate intermediate" evidence="3">
        <location>
            <position position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="254" mass="29016" checksum="B3A881EFFD282D3C" modified="2010-01-19" version="1">MPKHHYDLLALLAQPKVSQILALAEINAELETFTAQQRVEWALDHLTGEFALASSFGIQSAVMLHLVTQIKPDIPVILTDTGYLFPETYQFIDKLTQQLNLNLQVYRAPLSPAWQEAKYGQLWLQGIDGIKRYNQLNKVEPMRRALDELKVGTWFSGLRRQQSSTRASLPVLAIQNGVFKFLPVIDWSDEDIAHYIEAHQLSYHPLKEQGYRSIGDVHTSEKWQPGMKEEETRFFGLKRECGLHEDQEADGSGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0F7</accession>
    <name>D0Z0F7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 13">Replicative DNA helicase</fullName>
            <ecNumber evidence="4 13">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">VDA_003021</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 13">Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the helicase family. DnaB subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="4 13"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003021"/>
    <dbReference type="EnsemblBacteria" id="EEZ41988">
        <property type="protein sequence ID" value="EEZ41988"/>
        <property type="gene ID" value="VDA_003021"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0305">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990077">
        <property type="term" value="C:primosome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006269">
        <property type="term" value="P:DNA replication, synthesis of RNA primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00984">
        <property type="entry name" value="DnaB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036185">
        <property type="entry name" value="DNA_heli_DnaB-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007692">
        <property type="entry name" value="DNA_helicase_DnaB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007694">
        <property type="entry name" value="DNA_helicase_DnaB-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007693">
        <property type="entry name" value="DNA_helicase_DnaB-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016136">
        <property type="entry name" value="DNA_helicase_N/primase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00772">
        <property type="entry name" value="DnaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03796">
        <property type="entry name" value="DnaB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48024">
        <property type="entry name" value="SSF48024"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00665">
        <property type="entry name" value="DnaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51199">
        <property type="entry name" value="SF4_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 13" id="KW-0235">DNA replication</keyword>
    <keyword evidence="12 13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10 13 15" id="KW-0347">Helicase</keyword>
    <keyword evidence="9 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 13" id="KW-0639">Primosome</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SF4 helicase" evidence="14">
        <location>
            <begin position="175"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU362085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEZ41988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="446" mass="49447" checksum="5F6F50FC508CCC42" modified="2010-01-19" version="1">MPPHSLEAEQSVLGGLMLDNEKWDTVAEKVVAKDFYSRPHRLIFESAAAILDGGQPLDLITLSEQLEQNDKLEDVGGFAYLAELAKNTPSAANISAYADIVRERAIIRDMIGVANEIADAGYDPQGRTTDDLLDMAESKVFAIGEQRTNDKEGPQNVDSILEKTLERIELLYQSPQDGVTGVSTGFSDLNKKTAGMQPSDLIIVAARPSMGKTTFAMNLCENAAMDQDKPVLIFSLEMPSEQIMMRMLASLSRVDQTKIRTGQLDDEDWARISSTMGLLMQKKNIFIDDSSGLTPTEVRSRARRIARDHGGISLIMVDYLQLMRVPGMQDNRTLEIAEISRSLKALAKELNVPVVALSQLNRSLEQRADKRPVNSDLRESGAIEQDADLIMFIYRDEVYHEDSALKGIAEIIIGKQRNGPIGTVRLTFQGQFSRFDNYAGPAFDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0G2</accession>
    <name>D0Z0G2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">23S rRNA (guanosine-2'-O-)-methyltransferase RlmB</fullName>
            <ecNumber evidence="6">2.1.1.185</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">23S rRNA (guanosine2251 2'-O)-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">23S rRNA Gm2251 2'-O-methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rlmB</name>
        <name evidence="8" type="ORF">VDA_003026</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Specifically methylates the ribose of guanosine 2251 in 23S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>guanosine(2251) in 23S rRNA + S-adenosyl-L-methionine = 2'-O-methylguanosine(2251) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:24140"/>
            <dbReference type="Rhea" id="RHEA-COMP:10239"/>
            <dbReference type="Rhea" id="RHEA-COMP:10241"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74445"/>
            <dbReference type="EC" id="2.1.1.185"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.185" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301629.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003026"/>
    <dbReference type="EnsemblBacteria" id="EEZ41993">
        <property type="protein sequence ID" value="EEZ41993"/>
        <property type="gene ID" value="VDA_003026"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0566">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1422015at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070039">
        <property type="term" value="F:rRNA (guanosine-2'-O-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01887">
        <property type="entry name" value="23SrRNA_methyltr_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024915">
        <property type="entry name" value="23S_rRNA_MeTrfase_RlmB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="L30e-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004441">
        <property type="entry name" value="rRNA_MeTrfase_TrmH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013123">
        <property type="entry name" value="SpoU_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46429">
        <property type="entry name" value="PTHR46429"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08032">
        <property type="entry name" value="SpoU_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00967">
        <property type="entry name" value="SpoU_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="SSF55315"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00186">
        <property type="entry name" value="rRNA_methyl_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SpoU_sub_bind" evidence="7">
        <location>
            <begin position="5"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="218"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="227"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ41993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="247" mass="26656" checksum="D52801B620CE75DE" modified="2010-01-19" version="1">MSNEMIFGIHAVKAVLASDPSRFIEVFVLKGRQDERLLPILNELQMLGVTMQQAGRKALDDKVHGANHQGIVARVRPGKQFNENDLDAILAGKENPLLLILDGVTDPHNLGACLRNADAAGAVAIIVPKDRSAQLTATASKVACGAAEVVPLVRVTNLARTMRYLQEEKNIWIVGTAGEATHDIYQTKLTGPLAIVMGAEGEGMRRLTRETCDDLIKIPMAGSVSSLNVSVASGICLFEAVRQRIER</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0M6</accession>
    <name>D0Z0M6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NAD-capped RNA hydrolase NudC</fullName>
            <shortName evidence="2">DeNADding enzyme NudC</shortName>
            <ecNumber evidence="2">3.6.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">NADH pyrophosphatase</fullName>
            <ecNumber evidence="2">3.6.1.22</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">nudC</name>
        <name evidence="5" type="ORF">VDA_003090</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA. The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing. Has preference for mRNAs with a 5'-end purine. Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>H2O + NAD(+) = AMP + beta-nicotinamide D-ribonucleotide + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:11800"/>
            <dbReference type="ChEBI" id="CHEBI:14649"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="3.6.1.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>H2O + NADH = AMP + 2 H(+) + reduced beta-nicotinamide D-ribonucleotide</text>
            <dbReference type="Rhea" id="RHEA:48868"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:90832"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="3.6.1.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a 5'-end NAD(+)-phospho-ribonucleoside in mRNA + H2O = a 5'-end phospho-adenosine-phospho-ribonucleoside in mRNA + beta-nicotinamide D-ribonucleotide + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:60876"/>
            <dbReference type="Rhea" id="RHEA-COMP:15698"/>
            <dbReference type="Rhea" id="RHEA-COMP:15719"/>
            <dbReference type="ChEBI" id="CHEBI:14649"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:144029"/>
            <dbReference type="ChEBI" id="CHEBI:144051"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="2">Divalent metal cations. Mg(2+) or Mn(2+).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="2">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Nudix hydrolase family. NudC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.-" evidence="2"/>
    <dbReference type="EC" id="3.6.1.22" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003090"/>
    <dbReference type="EnsemblBacteria" id="EEZ42057">
        <property type="protein sequence ID" value="EEZ42057"/>
        <property type="gene ID" value="VDA_003090"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2816">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000210">
        <property type="term" value="F:NAD+ diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110153">
        <property type="term" value="F:RNA NAD-cap (NMN-forming) hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00297">
        <property type="entry name" value="Nudix_NudC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022925">
        <property type="entry name" value="RNA_Hydrolase_NudC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0464">Manganese</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="4">
        <location>
            <begin position="128"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="195"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Nudix box" evidence="2">
        <location>
            <begin position="162"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="181"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="222"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="244"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00297"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ42057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="263" mass="29768" checksum="56B84CFF48FB00B3" modified="2010-01-19" version="1">MTFMLKKRDTAYWCLVDDQGILLINHDLPCLSAEALGIDPKIAHHIGEFNHIPVYAIYAPPQLELGEYRSLRDLLFLPSPLFNLASRAMELGYMQKSQRFCTQCGGALTFTPDENAMRCQQCHMVHYPRLSPCIIVAVRKDESILLAQHPRHKNGMYTVIAGFVEAGETLEQCVAREVFEETGIVVDNIQYIGSQPWAFPSNLMMAFVADYQSGELKPDYAELTDAIWAHYQQLPPVAPKGTIARELIEQTLLRIKQGKDQQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0R0</accession>
    <name>D0Z0R0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Heat shock protein 15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_003124</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the HSP15 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301936.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003124"/>
    <dbReference type="EnsemblBacteria" id="EEZ42091">
        <property type="protein sequence ID" value="EEZ42091"/>
        <property type="gene ID" value="VDA_003124"/>
    </dbReference>
    <dbReference type="GeneID" id="57340648"/>
    <dbReference type="eggNOG" id="COG1188">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2006597at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003727">
        <property type="term" value="F:single-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034605">
        <property type="term" value="P:cellular response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025708">
        <property type="entry name" value="HSP15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016821">
        <property type="entry name" value="HSP15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="S4" evidence="5">
        <location>
            <begin position="12"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="105"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="115"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR016821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ42091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="135" mass="15470" checksum="64C1ECBC2DF12FAE" modified="2010-01-19" version="1">MSRQTPSVEDAVRLDKWLWAARFYKTRSIARSMIEGGKVQYNGQRSKPSKIVEVGAEIKLRQGNDEKTVTIEKISAARRGAPEAQTLYQETDSSIEQRERNAQLRKLNALGSPSPEKRPDKKQRRDIIKFKNVNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0T6</accession>
    <name>D0Z0T6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glutathione hydrolase proenzyme</fullName>
            <ecNumber evidence="4">2.3.2.2</ecNumber>
            <ecNumber evidence="4">3.4.19.13</ecNumber>
        </recommendedName>
        <component>
            <recommendedName>
                <fullName evidence="4">Glutathione hydrolase large chain</fullName>
            </recommendedName>
        </component>
        <component>
            <recommendedName>
                <fullName evidence="4">Glutathione hydrolase small chain</fullName>
            </recommendedName>
        </component>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_003150</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2 4">
            <text>an S-substituted glutathione + H2O = an S-substituted L-cysteinylglycine + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:59468"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:90779"/>
            <dbReference type="ChEBI" id="CHEBI:143103"/>
            <dbReference type="EC" id="3.4.19.13"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>an alpha-amino acid + an N-terminal (5-L-glutamyl)-[peptide] = 5-L-glutamyl amino acid + N-terminal L-alpha-aminoacyl-[peptide]</text>
            <dbReference type="Rhea" id="RHEA:23904"/>
            <dbReference type="Rhea" id="RHEA-COMP:9780"/>
            <dbReference type="Rhea" id="RHEA-COMP:9795"/>
            <dbReference type="ChEBI" id="CHEBI:77644"/>
            <dbReference type="ChEBI" id="CHEBI:78597"/>
            <dbReference type="ChEBI" id="CHEBI:78599"/>
            <dbReference type="ChEBI" id="CHEBI:78608"/>
            <dbReference type="EC" id="2.3.2.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 4">
            <text>glutathione + H2O = L-cysteinylglycine + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:28807"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:61694"/>
            <dbReference type="EC" id="3.4.19.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Sulfur metabolism; glutathione metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.</text>
    </comment>
    <comment type="PTM">
        <text evidence="4">Cleaved by autocatalysis into a large and a small subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the gamma-glutamyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.2" evidence="4"/>
    <dbReference type="EC" id="3.4.19.13" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003150"/>
    <dbReference type="MEROPS" id="T03.001"/>
    <dbReference type="EnsemblBacteria" id="EEZ42117">
        <property type="protein sequence ID" value="EEZ42117"/>
        <property type="gene ID" value="VDA_003150"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0405">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00204"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036374">
        <property type="term" value="F:glutathione hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102953">
        <property type="term" value="F:hypoglycin A gamma-glutamyl transpeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103068">
        <property type="term" value="F:leukotriene C4 gamma-glutamyl transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006750">
        <property type="term" value="P:glutathione biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006751">
        <property type="term" value="P:glutathione catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043138">
        <property type="entry name" value="GGT_lsub_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000101">
        <property type="entry name" value="GGT_peptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043137">
        <property type="entry name" value="GGT_ssub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00066">
        <property type="entry name" value="g_glut_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0317">Glutathione biosynthesis</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0865">Zymogen</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU368036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ42117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="644" mass="70064" checksum="09AA3509F5D41275" modified="2010-01-19" version="1">MLGSATTPLMKRDIKLSSRKYVPPSQYLMNNQAQRASSCYSCSQQSYLNKDEMMAKLAQKLLLALSGLLLSHTVIATVSQTSDHIAPELGDVRTQQQQITAQKWMVATANSYASEAGAEILQQGGNAIDAMVTIQLVLGLVEPQSSGIGGGAFLLYWDQEQQKLTSFDGRETAPFAATPQLFLDDKGQPLTFFDAVVGGRSVATPGTVKLLWQTHQQLGKLPWKSVVQPAIKLAQQGFIVSPRLANAIAQSQESLSKFAPTRAYFFHPDGTARQSGELLTNSDYAATLKQIAEHGAKAFYQGAIAKDIVATVRQAPTNPGVLSVLDLAAYQIKQRQPICAPYHQYQICGMGPPSSGALTVGQIMAMLSHYPMAKLGPNNITSWRLLADASRLAFADRGRYMADSDYVPMPKQGLLAPQYIEKRAQLLKGKKALAQVEPGLPSWPQAIKQADDQAIELPSTSHFVIVDKQKNVVSMTSTIENGFGSRLMVRGFLLNNELTDFSFRSQVDGVPIANRVEPGKRPRSSMAPTIVLKQGQPYLAIGSPGGSQIIGYVSKTLLGYLSWNLSLQQAIDLPNMNNRFGSYELEQNTEAEQWAEPLKKLGYQVQIKDLNSGVQAIALKPQSDGSIQLIGAADPRREGKVIGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0U3</accession>
    <name>D0Z0U3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_003157</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302030.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003157"/>
    <dbReference type="EnsemblBacteria" id="EEZ42124">
        <property type="protein sequence ID" value="EEZ42124"/>
        <property type="gene ID" value="VDA_003157"/>
    </dbReference>
    <dbReference type="GeneID" id="57340612"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032831">
        <property type="entry name" value="LPAM_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13627">
        <property type="entry name" value="LPAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0564">Palmitate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ42124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="38" mass="4099" checksum="005F8ACDC72EB967" modified="2010-01-19" version="1">MRKGLVAIFIFTILALTGCGQSGALYMPKDQPDQSQAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z186</accession>
    <name>D0Z186_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Acyl_transf_3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_003300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302436.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003300"/>
    <dbReference type="EnsemblBacteria" id="EEZ42267">
        <property type="protein sequence ID" value="EEZ42267"/>
        <property type="gene ID" value="VDA_003300"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3274">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1979131at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002656">
        <property type="entry name" value="Acyl_transf_3_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01757">
        <property type="entry name" value="Acyl_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="156"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="179"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="204"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="243"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="281"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="308"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl_transf_3" evidence="2">
        <location>
            <begin position="8"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ42267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="337" mass="38695" checksum="D63B476489758197" modified="2010-01-19" version="1">MAAKKIWFFDLLRCVAAIAVVIIHVLGPYREQLGQIPQFDWITAITFNSFSRWAVPVFILISGALLLSNPKPIEANYFITRRVSKVLIPFVAWSLFYAGLAGVSLSGFDGAVSINLLKHAFTHETYYHLGFFYYFIPLYLLVPLFHFFVHRAEPSQVRAVIGVWLIFTLLFLLRVDGPWSNQYVLYSGYLLLGYGLYQYQRPKLVWLLPLGVVALLLTDWMVVHLSLVVGEYTVGRWLSYKTLNTVLIASLVFVGCRWWAEHCEWSVTAKQGISFISRYSLGVYLLHPLFLWPVIHLNWYFAPPLITIPFWTLVCGGLALLSSWLLSKSRYSAWLVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z194</accession>
    <name>D0Z194_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Protein GlpG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_003308</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302457.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003308"/>
    <dbReference type="EnsemblBacteria" id="EEZ42275">
        <property type="protein sequence ID" value="EEZ42275"/>
        <property type="gene ID" value="VDA_003308"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0705">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2053476at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038236">
        <property type="entry name" value="GlpG_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022732">
        <property type="entry name" value="Peptidase_S54_GlpG_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023662">
        <property type="entry name" value="Rhomboid_protease_GlpG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12122">
        <property type="entry name" value="Rhomboid_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="SSF144091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04239">
        <property type="entry name" value="rhombo_GlpG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="146"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="178"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="202"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="233"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="Rhomboid_N" evidence="9">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="Rhomboid" evidence="8">
        <location>
            <begin position="136"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ42275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="281" mass="31946" checksum="560115F05CEF0E62" modified="2010-01-19" version="1">MHRLIGLSNPRLAQAFIDYMASRKIEIVMSPESEGLFALWLKDEQHLVEAEAELQAFLHDPTADKYQAASWDMAESRTAKFHYANPSLINMIRAQAGPFTLFVMVAVITIYILWLIGFEQPLFTALHFPFFADGDQWQLWRYFSHALLHFSALHIIFNCLWWWLLGGKIEQHSGSSKLVQIFLLSSLLSGFAQAWFVGPNFGGLSGVVYALMGYLWWMGWLAPKRGLTIPRSYVVFMLVWLILGFTDILGFSVANMAHLFGLASGCLIALYDAKKPLKHHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z195</accession>
    <name>D0Z195_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Glycerol-3-phosphate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_003309</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003309"/>
    <dbReference type="EnsemblBacteria" id="EEZ42276">
        <property type="protein sequence ID" value="EEZ42276"/>
        <property type="gene ID" value="VDA_003309"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2271">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021159">
        <property type="entry name" value="Sugar-P_transporter_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00942">
        <property type="entry name" value="GLPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="120"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="159"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="190"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="219"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="251"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="282"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="7">
        <location>
            <begin position="1"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ42276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="318" mass="35260" checksum="983E88A9878C39CF" modified="2010-01-19" version="1">MGWPACGRTMVHWWSHKERGGIVSVWNVAHNVGGGLIGPLFLLGLWLFHDDWRSAFYVPAFGALIVAAFVLIVMRDTPQSCGLPSIEEYKNDYPDSYDASFEKEMTAKEIFFKYVFNNKLLWYIAIANAFVYLIRYGVLDWAPVYLSEAKDFTVDKSSWAYFLYEWAGIPGTLLCGWMSDKFFKGRRAPAGILFMVLVTLAVLVYWFNPAGNPTIDMMALVAIGFLIYGPVMLIGLYALELAPKKAAGTAAGLTGLFGYLGGAVAANAVLGYTVDHFGWDGGFLVLTVSCGLSIIFFILAMMGESKIHKEKLLKQQNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1E0</accession>
    <name>D0Z1E0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Epimerase_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_003354</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UDP-N-acetylglucosamine 2-epimerase family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302557.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003354"/>
    <dbReference type="EnsemblBacteria" id="EEZ42321">
        <property type="protein sequence ID" value="EEZ42321"/>
        <property type="gene ID" value="VDA_003354"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1887">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1162846at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043148">
        <property type="entry name" value="TagF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016886">
        <property type="entry name" value="UCP028458_glyceroPtfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003331">
        <property type="entry name" value="UDP_GlcNAc_Epimerase_2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02350">
        <property type="entry name" value="Epimerase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028458">
        <property type="entry name" value="UCP028458_glyceroPtfrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase_2" evidence="2">
        <location>
            <begin position="134"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ42321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="351" mass="40527" checksum="EC783D13148291CB" modified="2010-01-19" version="1">MAKRYLMYIAQNYSYAILRPLQEAILHRGGEVCWFLEGKEVDANFLLPNERRLNTIAEVKAWQPDAVFVPGNVVPRFVPGIKVGVFHGFDAGKMNRRGREDHYEIRGCFDLYCTQGPNTTLRFEQLAKEYGFFKVKQTGWPMMDPLFQPSHDNPYLDKKDERPTILMCSTFSRNLTCAPHLIETIKRLSQSGKWRWLIQFHPKMDSAIVEQYKALQGPNLTFVETDNVIPLLQAADVMLCDTSSVLLMFLLQRKPVVTFRNQSPKPHLINIEQANLVEDALTQALTRPPELMAEIEQYCQMIHPYYDGKSSERVLAAADEMIESGLVGLKNKPLNMIREFKMRKKLHFWGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z202</accession>
    <name>D0Z202_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HlyD_D23 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001963</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299032.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001963"/>
    <dbReference type="EnsemblBacteria" id="EEZ40931">
        <property type="protein sequence ID" value="EEZ40931"/>
        <property type="gene ID" value="VDA_001963"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1566">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="757027at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="5"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="2">
        <location>
            <begin position="42"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="298" mass="33228" checksum="4CBE188953A88534" modified="2010-01-19" version="1">MKKTIVILVNLLIIGGAVWLGYQKYQEYFNNPWTRDGQVRANVIKVAPRVSGPITNVAVIDNQMVNKGDLLFEIDSSTYDVALSKAQVSLERSIISSKGKKIEYDRLRDIRAKDRGAVSHKDLIRRQIAYEESLLQIQIAKEQLKAAELNVSFTKVYASVDGYVSNLDIQTGTQAVANQPLIALIDKNSFWVFGFFRENQIAAIHAGSQAKVTLMSHPDLSIDAKVASIGWGIAPKDGTVGYNLLPNVNPVFQWIRLAQRIPVRIELEALPENLDLRFGMSASIMVLQDTASDENQDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z222</accession>
    <name>D0Z222_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hypothetical sigma-54 modulation protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001871</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001871"/>
    <dbReference type="EnsemblBacteria" id="EEZ40839">
        <property type="protein sequence ID" value="EEZ40839"/>
        <property type="gene ID" value="VDA_001871"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1544">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044238">
        <property type="term" value="P:primary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036567">
        <property type="entry name" value="RHF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003489">
        <property type="entry name" value="RHF/RaiA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02482">
        <property type="entry name" value="Ribosomal_S30AE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69754">
        <property type="entry name" value="SSF69754"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0810">Translation regulation</keyword>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="25"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="81" mass="9184" checksum="EDBB74C46268395E" modified="2010-01-19" version="1">MKLEPEKNFHVEIATRSNLGQIDASADSKELIEALNEAFARLERQLIKNKEKPMSHMADHAEKQKAKLIADELEQEAVADK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z239</accession>
    <name>D0Z239_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001775</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298676.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40743">
        <property type="protein sequence ID" value="EEZ40743"/>
        <property type="gene ID" value="VDA_001775"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1624315at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019329" evidence="1">
        <location>
            <begin position="23"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="184" mass="20571" checksum="964DFA7003F5D425" modified="2010-01-19" version="1">MKKWALLTTAIILGAGSLYVGAQNNESEPLTQLVKHPQHWQVMVPDTQSSIHLDAIEKLQQQPYLVGHYQGEDEGDNSTIYLDTNQIKQSNNYLASTFIMTNSGSGSFYYLALFKENANKLNNVANVFIGDRIAVEKINILKTDPVTIQIDYKTHGENTPYALPADVAKSQVYVLDNNQLVLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z240</accession>
    <name>D0Z240_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001776</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298678.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001776"/>
    <dbReference type="EnsemblBacteria" id="EEZ40744">
        <property type="protein sequence ID" value="EEZ40744"/>
        <property type="gene ID" value="VDA_001776"/>
    </dbReference>
    <dbReference type="GeneID" id="57342119"/>
    <dbReference type="eggNOG" id="ENOG5032VT8">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1728561at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="174"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="203"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="224" mass="24052" checksum="862C642ACD2B79F8" modified="2010-01-19" version="1">MATGYLTFLIPALLGAQLVFSLVLTKGEICPGQRGRVHKTLPVLLLGWIIATIAQPFAVLPFLALAFFTVKVKTGKTRDAGPIKALYGADVLAAFCWLLLLPSMTLAQTGLSLVSIVLFGALVGHLLLTQARTRLQAFHKILPFAGFASGILAVLCLCAHMMTLSEQQVSQLTGSFIAALVLLVASLLVWVGHILLHKTVNKWQLLVALALLILSGAIQLNLFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z252</accession>
    <name>D0Z252_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001788</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298702.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001788"/>
    <dbReference type="EnsemblBacteria" id="EEZ40756">
        <property type="protein sequence ID" value="EEZ40756"/>
        <property type="gene ID" value="VDA_001788"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1661500at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="306" mass="34847" checksum="90826C9C7336D8E3" modified="2010-01-19" version="1">MLKKAQQMVVFNALTKQQSFTKAAQLLDISRTQVSKQIQLLEERLGVQLVQRTTRSFALTEAGKAFAAHCANIVAEINEAESELLSDCDTLQGTLKVGVAQSFASNHLAPYIAEFHAQYPQLKLEMSLFDHRVDIIAEQLDLWIGMMDSPPEGFVARHLVDCHFVLAASPEYLALHGVPYHPRDLKEHNCITYFSRERKDNVWSFKKDDEALQIKVSGNYRVDSADAIRDATLTGNGIGYLATYLLKDELRQGKLIRLLPDWDLNQYMPLYAVYPRHKFLPIKVQAFIDFVRQHIGNPPYWDQGIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2E3</accession>
    <name>D0Z2E3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative regulator protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000594</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000594"/>
    <dbReference type="EnsemblBacteria" id="EEZ39574">
        <property type="protein sequence ID" value="EEZ39574"/>
        <property type="gene ID" value="VDA_000594"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0714">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022547">
        <property type="entry name" value="ATPase_RavA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045427">
        <property type="entry name" value="MoxR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041538">
        <property type="entry name" value="RavA-like_AAA_lid"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17868">
        <property type="entry name" value="AAA_lid_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20030">
        <property type="entry name" value="bpMoxR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12592">
        <property type="entry name" value="DUF3763"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="3">
        <location>
            <begin position="46"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="550" mass="62427" checksum="0BA5CFDBC377B699" modified="2010-01-19" version="1">MFSMANRTTTNNALISERIQKLIKGLSNGVYEREETIKLCMLAALAGESVFLLGPPGIAKSLIAKRLIQAFDNSHFFDYLMTRFSTPEEVFGPLSIQELKDNGKYVRLTEGYLPTAQVVFLDEIWKAGPAILNTLLTVVNEKTFKNGQDVLPVPMRLLITASNELPDADSGLDALYDRMLVRVFVNRIQEKQNFKAMLMGDGPSLQELDPKLAITDEEYTSWQEQIDDVVLTDEIFESIYYIKTQIEKHCDSDEMSLADNELYVSDRRWKKSIRLLKASAFFNGRHEVNPLDLLLLQDCLWSSPESRNVINQIMAEFATKKAFNQVAVTQDANEAQTIINSVNGDVAQQLAIKFTRESTLRKEWFKYNFATAKRFNINNNPRMIKLVMLEPNPSVSEQEPGDSRWVYVDGEEFDKKIRTGQCDVYGYVNKNTHLCRLQFEIDAEQRLVIKDIANRSVLVGIAGTKGLTATQHQEWLTKVESATAKLVDADHNIKKSRASFHGALPHNFINISVPALIEQSLNDSVESVNELKLSIEKNAFRINQLSEYFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2F6</accession>
    <name>D0Z2F6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000607</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304851.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000607"/>
    <dbReference type="EnsemblBacteria" id="EEZ39587">
        <property type="protein sequence ID" value="EEZ39587"/>
        <property type="gene ID" value="VDA_000607"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3496">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1256871at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010775">
        <property type="entry name" value="DUF1365"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33973">
        <property type="entry name" value="PTHR33973"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07103">
        <property type="entry name" value="DUF1365"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="292" mass="34427" checksum="3AF2C5E98F1521F0" modified="2010-01-19" version="1">MGKVIGDDYTGHGLYVGIVRHRRFNPIKHSFCYPIFMTYLELDSLDLLLEQKWWFGTRPWCWVRFRFQDYLNSDNVTYPTTGKELKQAVLEKLTQLTGMDMSAITRVNMLGHLRYGGLYFSPLNLYYCFNEHNELCWVLAEVSNTPWNQRHYYALPILTKSEGDKSQKPSQRFTVEHLKAFHVSPFNPMEQRYSWLLNQPQTVLSVHLEILTLTDDKHQTSRYSNSCSEQTRAIKVFDATMKLKYQPFTGHRLGKQLIITPIMTIKVIIGIYWQALKLWIKKAPFYNHPTRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2G8</accession>
    <name>D0Z2G8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000619</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304890.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000619"/>
    <dbReference type="EnsemblBacteria" id="EEZ39599">
        <property type="protein sequence ID" value="EEZ39599"/>
        <property type="gene ID" value="VDA_000619"/>
    </dbReference>
    <dbReference type="GeneID" id="57342895"/>
    <dbReference type="eggNOG" id="ENOG5032NMR">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="945768at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021290">
        <property type="entry name" value="DUF2861"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11060">
        <property type="entry name" value="DUF2861"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018787" evidence="1">
        <location>
            <begin position="26"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="288" mass="32860" checksum="C2982B5AF1FC3013" modified="2010-01-19" version="1">MKRLTASLCSLFLVGSAFCTPSASAKWFISKNLYTLANEKLLEGHTSESFDTIIQAWQQQPDAIHQANLNNLLDLAITDDCGHSLNKKVLPQWLSQLSVNREVIQNTNQLMLKLSITGLTRNKIKSISFSRWPDMDIIKGTPLIEEGGYFNIEARRLEKPIHAGLYRLSIQAEDEKPWNSWIVLAEPALKQQIGWVDNSHWRIEHNYFQNPSCPTPALTVDLFDLNNSSWTPVWSQRINNKDLPNELPEVSLPDGRYWLSVGLINSRWQGDIAIKDVQRITQPVDFPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2J8</accession>
    <name>D0Z2J8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000649</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000649"/>
    <dbReference type="EnsemblBacteria" id="EEZ39629">
        <property type="protein sequence ID" value="EEZ39629"/>
        <property type="gene ID" value="VDA_000649"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025985">
        <property type="entry name" value="YnbE-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13617">
        <property type="entry name" value="Lipoprotein_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="38" mass="4442" checksum="0C3843A5D2AD7C6A" modified="2010-01-19" version="1">MATSDKPIEVNLNVKIEHEIRIKVDKEIDNLFKDEAVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2L2</accession>
    <name>D0Z2L2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Hexose phosphate uptake regulatory protein UhpC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_000663</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000663"/>
    <dbReference type="EnsemblBacteria" id="EEZ39643">
        <property type="protein sequence ID" value="EEZ39643"/>
        <property type="gene ID" value="VDA_000663"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2271">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021159">
        <property type="entry name" value="Sugar-P_transporter_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000849">
        <property type="entry name" value="Sugar_P_transporter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002808">
        <property type="entry name" value="Hexose_phosphate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00942">
        <property type="entry name" value="GLPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="80"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="145"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="252"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="283"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="307"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="343"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="370"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="7">
        <location>
            <begin position="1"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ39643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="408" mass="44106" checksum="88E70D9C7AB8784C" modified="2010-01-19" version="1">MYISRKAFAAAAPLLMEDLGMTAVQFGMASSIYYILYGLSKFSSGLLADRINPRLFLAPVLVVIAIINVGIGMSNSVTTLLTLYCLTAVVQGCGFPPIAKAISQWYSKSERGGWYSLWNTSHNVGGALAPLIASAVIASTGNWRYAFYVPAIITAVQAIIAAVFMRGKPENYGLPNVGVWKNDTKQLEINKNSEAGLSMWTMFKRYILTNPIIWLAIGGDLCIYIIRTVSTDWVNVYFVKQLGWDLMKSNSLVAWFEAGGILGGLTSGIISDKFFGADRWKTILIYSFVLIAGMIGVMLTIHIDYMLVALCFFIIGAGIYAPQMLFALGIIEASHADGAGAATGLKGGVTYVGAALAGAPIAMLKNAYSWNGVFILLGSIAAILVILICVIIIFDRKKRQAMEQHAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2M9</accession>
    <name>D0Z2M9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Alpha-1,4 glucan phosphorylase</fullName>
            <ecNumber evidence="10">2.4.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">VDA_000680</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.</text>
    </comment>
    <comment type="function">
        <text evidence="8">Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>[(1-&gt;4)-alpha-D-glucosyl](n) + phosphate = [(1-&gt;4)-alpha-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:41732"/>
            <dbReference type="Rhea" id="RHEA-COMP:9584"/>
            <dbReference type="Rhea" id="RHEA-COMP:9586"/>
            <dbReference type="ChEBI" id="CHEBI:15444"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="EC" id="2.4.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 10">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the glycogen phosphorylase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.1" evidence="10"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305042.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000680"/>
    <dbReference type="EnsemblBacteria" id="EEZ39660">
        <property type="protein sequence ID" value="EEZ39660"/>
        <property type="gene ID" value="VDA_000680"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0058">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="137158at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008184">
        <property type="term" value="F:glycogen phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102250">
        <property type="term" value="F:linear malto-oligosaccharide phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102499">
        <property type="term" value="F:SHG alpha-glucan phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011833">
        <property type="entry name" value="Glycg_phsphrylas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000811">
        <property type="entry name" value="Glyco_trans_35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035090">
        <property type="entry name" value="Pyridoxal_P_attach_site"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11468">
        <property type="entry name" value="PTHR11468"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00343">
        <property type="entry name" value="Phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000460">
        <property type="entry name" value="Pprylas_GlgP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02093">
        <property type="entry name" value="P_ylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00102">
        <property type="entry name" value="PHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4 10 11" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6 9 10" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10 11" id="KW-0808">Transferase</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="9">
        <location>
            <position position="666"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000460-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ39660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="820" mass="92800" checksum="1161E9D03B672871" modified="2010-01-19" version="1">MTTRAPKQHFDKELFKNAVKKHLSATYAQSSATASSRSWYLALGRALAEISTEGLLTTADAVAKANTRSVNYLSLEFLIGRLTGNNLISLGLYEEVSQAMEELGQNLTDLLEEERDPALGNGGLGRLAACFMDSLAAQEYPAVGYGLHYEYGLFRQSFEDGRQTEAPDAWRGVEGYPWEVVRPELTQNVGFYGHVEQYQNEQGETCSRWIPGMFVEGIAWDLPIIGYANKSVYPLRLWECRAPAPFNLARFNDGDYVGAQYSQLEAANVTKVLYPNDNHEQGKVLRLMQQYFHCACSVADILRRHNALGRDIHDLAKFESIQLNDTHPTIAIPELMRILLDEYQLSWQQAWAITSKTFAYTNHTLLPEALETWSENLIAQLLPRHMEIIFEINHHFMLQVEAHWPNNNEVKRKLSIIQEGPQRMVRMANLCVVGSYAVNGVAALHSELVKRDLFPEFNELFPGRLQNVTNGVTPRRWLKFCNPGLSALISEKIGTEWPAKLEQLSQLEKFADDKAFQQRYMAVKKANKQRFADWVLDNMGIELDTNAIFDVQIKRLHEYKRQHLNLLHILSLYHRLLNEPEFDMHPRVFIFAAKAAPGYALAKDIIFAINKVAEKVNNDARLGGKLKVVFVPDYRVSLAEIIIPAADVSEQISTAGKEASGTGNMKLALNGALTIGTMDGANVEIREEVGDDNIFIFGLLVDEVMKTLEQGYQPYDYYHNNALLKAALDLLQGDEFTPGQSGQLQAIRYNLLDGGDPYLVLADFADYVKAHERIDAEYRDQQNWARKTILNTALVGKFSSDRSIRDYVNNIWKLTAVHQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2P7</accession>
    <name>D0Z2P7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cation ABC transporter cation-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_000698</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the bacterial solute-binding protein 9 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305089.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000698"/>
    <dbReference type="EnsemblBacteria" id="EEZ39678">
        <property type="protein sequence ID" value="EEZ39678"/>
        <property type="gene ID" value="VDA_000698"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0803">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1703187at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030001">
        <property type="term" value="P:metal ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006129">
        <property type="entry name" value="AdhesinB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006128">
        <property type="entry name" value="Lipoprotein_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006127">
        <property type="entry name" value="ZnuA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01297">
        <property type="entry name" value="ZnuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00691">
        <property type="entry name" value="ADHESINB"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00690">
        <property type="entry name" value="ADHESNFAMILY"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0732">Signal</keyword>
    <keyword evidence="1 3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005341753" evidence="4">
        <location>
            <begin position="24"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="307" mass="33912" checksum="6A2580761D1976BD" modified="2010-01-19" version="1">MKKYFLLLAGFLIGVFNAHFALASDNKLTIGITLQPYYSYVKAVVGDKATILPLVDAGFNPHNYQPQPNDLRRLKEMDVIVVNGIGHDDFALKVIKAANRSDLKVIEANKEVPLLPAMGQSVGQGAVNPHTFVGLSTTIQKVYTIASELSKIDPNNARFYRANARQYAATFRKMKHVAMQSLGELNTAGMTVATTHNAYGYLLQEFGVDVAAVIEPAHGVEPSASQLQETIEKIQRSGIDVLFYELNMPNRYVDTIEKATGVKLYRFSHMTHGPYQAEKVEVEMQENINTLMAAMKFAATKTTVVTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2S2</accession>
    <name>D0Z2S2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">C factor cell-cell signaling protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000723</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305162.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000723"/>
    <dbReference type="EnsemblBacteria" id="EEZ39703">
        <property type="protein sequence ID" value="EEZ39703"/>
        <property type="gene ID" value="VDA_000723"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="968232at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="240" mass="26370" checksum="CA26AA0323FC156B" modified="2010-01-19" version="1">MNILILGGSGGIGQALIKHILMMPAKHQIWATYHLADPTKLCLSSPQLHWTQLDLTKESQIAQLSQSLSQVDIIINTVGLLHNTDLALVPEKALSQLNSSHFLTVIQTNALPSILIAKHFEHHLKRSATPRFCTLSAKVGSIEDNHLGGWISYRCSKAALNMAIKTIAIEWQRTIPDACIFVIHPGTTKTSLSEPFQANIPPGQLRTSTETAAAIITQLQRINSKQSGTFIDYNGEVLPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2Z9</accession>
    <name>D0Z2Z9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Secreted trypsin-like serine protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_000800</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305387.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000800"/>
    <dbReference type="EnsemblBacteria" id="EEZ39780">
        <property type="protein sequence ID" value="EEZ39780"/>
        <property type="gene ID" value="VDA_000800"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1468733at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020008">
        <property type="entry name" value="GlyGly_CTERM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03501">
        <property type="entry name" value="GlyGly_CTERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase S1" evidence="4">
        <location>
            <begin position="33"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="330"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU363034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="401" mass="43000" checksum="13669938A01CD405" modified="2010-01-19" version="1">MKGFQKIALGTALILGVLSPLTQVYAMKVAPKIIGGDDVNFSPNENMMVSLRANEVDEMPFCGGTIIGEQWLLTAAHCVVLGSGDGLFVIKPSQLTITAGITDNSDANVENMYVATHVVVHPDYTQDAKVKVDNQGNIELIHSALNNDLALIRVDNKFTDLGMSVLANDELANETDVLLSTQWDDHDRPKNVRILGWGATLPDGSSPSDSLKQATLSFLPIADCFVRIENGSSPALVIDSPTNRTKICTLPPEKIAQSLSVGVDSCFGDSGGPLFTQTVEGQTIQIGIVSGSTVGSPACGSLSRPTFYTRIGTYYDWITETIKKTPQKPITYPNIIKDPDSDGDNGGGTGEIPCNDSISPNNCALVGKDSGGSMGWWSLFLLGGLFWKRNKEHNSMPNYQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z335</accession>
    <name>D0Z335_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cupin_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000836</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305485.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000836"/>
    <dbReference type="EnsemblBacteria" id="EEZ39816">
        <property type="protein sequence ID" value="EEZ39816"/>
        <property type="gene ID" value="VDA_000836"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1917">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1928636at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_2" evidence="1">
        <location>
            <begin position="43"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="107" mass="12230" checksum="134B07673788D9FC" modified="2010-01-19" version="1">MFNYTLYENLLEEIEIPRVGITSRPLYQGDKVRAVIFGFAENEEMTEHTASSPAIVQVLEGECIFTFDQEPRTMTPGSWAIMDAKMPHSIQATKPLKFLLHLLKDNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z368</accession>
    <name>D0Z368_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000869</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305582.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000869"/>
    <dbReference type="EnsemblBacteria" id="EEZ39849">
        <property type="protein sequence ID" value="EEZ39849"/>
        <property type="gene ID" value="VDA_000869"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4681">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1464975at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009822">
        <property type="entry name" value="YaeQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038590">
        <property type="entry name" value="YaeQ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38784">
        <property type="entry name" value="PTHR38784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07152">
        <property type="entry name" value="YaeQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF011484">
        <property type="entry name" value="YaeQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01322">
        <property type="entry name" value="YaeQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="179" mass="20794" checksum="963DD4C2772CC376" modified="2010-01-19" version="1">MALKATVYKAHINVADMDRHVYLDVNHTVACHPSETIQRFMLRILAWGLNADENLKFTKGLCDTDEPDLWIVNYSDEIELWVELGLPDEKRLRKASHKAQKVILFAYDNNAATIWWQQNQNKINTLDNVSVVFINDQTLVELEQVAERSMQLQLTIEGEQAWLSSDKGNVTIIPEWWKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z396</accession>
    <name>D0Z396_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Methyl-accepting chemotaxis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_000897</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the methyl-accepting chemotaxis (MCP) protein family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305663.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000897"/>
    <dbReference type="EnsemblBacteria" id="EEZ39877">
        <property type="protein sequence ID" value="EEZ39877"/>
        <property type="gene ID" value="VDA_000897"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0840">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="429006at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0807">Transducer</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="13"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="192"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="6">
        <location>
            <begin position="216"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="5">
        <location>
            <begin position="275"/>
            <end position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00029447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="547" mass="59959" checksum="77794B127F2C66E4" modified="2010-01-19" version="1">MQWFKNLSFRWKFAIPMAFIVSIFLLIIGFALVVFSNVAESERIQRAEVQPVLDKLEDGYRDLYQVVTAGQGIILAKGDAKLLAYHQFEFEDNGSKALPRLMSVQELIDSKFLPTSTQSQLSQLRSTYEAWIQHYSYMADNPMLAESYSRENDAQMNKEFEQLRSQLKGIRGQIESSLTELRQSIESDIRQAVLSLQIGGFIALMLAIVVVLGVGQVVLAPMQRLRIAMENIATGDGDLTQRVPVESSDELGQLATSFNQFVDKIHVTVQAVYQTINTVSSQAVQIKDTTQTVVERVVDQQEQSALAATAVNEMSATSDTVSQHASEAAQASQLVSDESNAAKVVLHQTVAAINQLSEEIESSSIVISDLERDVSNIASILDVIRGIADQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLASKTQESTGEIQIMIERLQQGANQAVKAMSLSSQSGIATVEQANNANRSLESITDSINVVNEMNLQIATAATQQSQVSEDINLNIQKIADNSQDVVVSSNQCHDIIQDLATKCEQLDTLIRQFKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3C7</accession>
    <name>D0Z3C7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">KAP NTPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000928</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39908">
        <property type="protein sequence ID" value="EEZ39908"/>
        <property type="gene ID" value="VDA_000928"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4928">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011646">
        <property type="entry name" value="KAP_P-loop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07693">
        <property type="entry name" value="KAP_NTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="KAP NTPase" evidence="2">
        <location>
            <begin position="184"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="384" mass="44487" checksum="80D5534D386C1B17" modified="2010-01-19" version="1">MNSILRYLSISIIFSIGYAFWSAIGPIIFKTKWFLSWCDFYLNLASWLQCMILFLSGFIINKILSWSGDYDINHENQGYLERLKYPPIRYAIAFSLISSIYYSDIYPYVYFDYQLLFLVLGLIFLFLHDFISTCNKKTDNLLFTLDESPIRSSSEDLYNREHIVNKILKRIKSNNYNYLKGQTIVGDYGSGKTSLLNLIEERIDKKDNIIICKFDSWGRITDAQQGQKLILEKIIEDIGKYTGVSDIKSVPKDYLNSLSGIDSRLKGIIDIINATSLDTEKQLNKIDNTLKAINKKLLVFIEDMDRNNNSEELANDISPLLDRLVCVPHITFIFTIGYDTHISSIINRITNYREDLVTDDSSTEKLLTKFRELSINCIKEKKLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3H3</accession>
    <name>D0Z3H3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">TPM_phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_000974</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305882.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000974"/>
    <dbReference type="EnsemblBacteria" id="EEZ39954">
        <property type="protein sequence ID" value="EEZ39954"/>
        <property type="gene ID" value="VDA_000974"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3762">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1927539at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007621">
        <property type="entry name" value="TPM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04536">
        <property type="entry name" value="TPM_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="38"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="TPM_phosphatase" evidence="5">
        <location>
            <begin position="102"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ39954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="205" mass="23397" checksum="36BD6D21E02C76D8" modified="2010-01-19" version="1">MKMFSEQELQQISQTIGNIEQQTDAELMAVIATASDDYYFVPTLWAAIIALFTPALLYLSPLWLDITDLLMAQLAVFVALTLLFRVPTIKYRMIPKSVKYRRASLLAHQQFLLNGIHKTQQHLGMMIFVSEADHYVEIITDYGISQQIDNQVWQKLVQDFTQNVKQGNTYQGYIQCLTASGEVLAQHFPLTQQKNELPNALVVID</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3H7</accession>
    <name>D0Z3H7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Iron-containing alcohol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000978</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the iron-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305892.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000978"/>
    <dbReference type="EnsemblBacteria" id="EEZ39958">
        <property type="protein sequence ID" value="EEZ39958"/>
        <property type="gene ID" value="VDA_000978"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1979">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="717704at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990362">
        <property type="term" value="F:butanol dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08187">
        <property type="entry name" value="BDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001670">
        <property type="entry name" value="ADH_Fe/GldA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044731">
        <property type="entry name" value="BDH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43633">
        <property type="entry name" value="PTHR43633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00465">
        <property type="entry name" value="Fe-ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe-ADH" evidence="3">
        <location>
            <begin position="8"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="382" mass="41772" checksum="5F1A7668C827949C" modified="2010-01-19" version="1">MQFTYVNPTLIHFGQGQIAAITNDIPTTSKVLVIYGGGSIKKNGVYDQVVKALENHTWLEFSGVEPNPTKETLDKAVAIVKEQGVDYILAVGGGSVIDGSKYVAAAAKYDGDGWDILIGKHTIESATPIGAILTLPATGSESNMGAVITKAETQDKLAFLHPAVQPKFAVMDPDVMKTLPERQLINGIVDAWVHTCEQYLTKPTHAMVQDGYAEVLLRNLKTLGDHYAERDNDEWRANLMWTANQALNGLIGSGVPQDWSTHMIGHELTALWHVDHARSLAIVQPSLLRNQIEYKRAKLEQMGRNVFGLEATSDLAERTIDAIEAFYHQLGVATQLTEYTGDKESAVSAVIDQLGKHGMTALSENQSITLERSREILENAIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3I0</accession>
    <name>D0Z3I0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Thioredoxin peroxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000981</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000981"/>
    <dbReference type="EnsemblBacteria" id="EEZ39961">
        <property type="protein sequence ID" value="EEZ39961"/>
        <property type="gene ID" value="VDA_000981"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1225">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="90" mass="10111" checksum="4773643884C5E5C3" modified="2010-01-19" version="1">MTFPIAYGLTVSQMEQLGLYISEPRSEKETDHLFAEPGLFVINDKGQLQIVDISNGPFVRPELEVLLSGIGFIRDPNNHYPIRGMYQGEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3K2</accession>
    <name>D0Z3K2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001003</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001003"/>
    <dbReference type="EnsemblBacteria" id="EEZ39983">
        <property type="protein sequence ID" value="EEZ39983"/>
        <property type="gene ID" value="VDA_001003"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031VI1">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="70" mass="7597" checksum="605D23481D5FE6F3" modified="2010-01-19" version="1">MVNAGNAAKSQVYDLSAQGDKLTSQVEQECAHLKKVTADDADGTKAKVKWATCYANAWSAARDQFLGEKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-02-10" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3K7</accession>
    <name>D0Z3K7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Arginine/ornithine antiporter ArcD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_001008</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305972.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001008"/>
    <dbReference type="EnsemblBacteria" id="EEZ39988">
        <property type="protein sequence ID" value="EEZ39988"/>
        <property type="gene ID" value="VDA_001008"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1288">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="350103at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018385">
        <property type="entry name" value="C4_dicarb_anaerob_car-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018387">
        <property type="entry name" value="YcgA/YfcC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43652:SF6">
        <property type="entry name" value="PTHR43652:SF6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03606">
        <property type="entry name" value="DcuC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="84"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="146"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="170"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="201"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="263"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="285"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="318"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="420"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="445"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="468" mass="49996" checksum="C57228F3296A7E5C" modified="2010-01-19" version="1">MKKLKFPSAYTILMLLTVFMAALTWLIPAGQYQMVNNETLGKMVPLVGSYQTVTSNPQGIIDILMAPIQGFYDPGEYMARAVDVALFVLVIGGYLAVVTRTGAIDAGIAGTMEKLNGREKWMIPILMGLFALGGTVYGMAEETIPFYALLIPVMIAAGYDSIVGVAIIMVGAGIGCLGSTINPFATVIASNAAEINFMDGIGLRLAILILGWIMCTIYVMRYAEKVKNDPSQSIVASQKDENERLFLHGKEQETPKLNTTRKIVLMIFGLTFAVMMWGVSVQGWWMAELSALFIGSSILVGFIGRLSETELTDSFVDGARDLLGVALIIAIARGLVVVMDDGNITHTILNYAEGLLAGLPQIAFINAIYWVEAVLCLVVPSSSGLAVLSMPVLAPLADFAGVSRELVVTAFQSASGLPNLVTPTSGVVMGGLAIGRVAYSSWLRFIGPLLGMLTLMVMILLSLGVVIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3Q5</accession>
    <name>D0Z3Q5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Long-chain fatty acid transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_001056</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell outer membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the OmpP1/FadL family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306101.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001056"/>
    <dbReference type="EnsemblBacteria" id="EEZ40036">
        <property type="protein sequence ID" value="EEZ40036"/>
        <property type="gene ID" value="VDA_001056"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2067">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="620166at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005017">
        <property type="entry name" value="OMPP1/FadL/TodX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35093">
        <property type="entry name" value="PTHR35093"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03349">
        <property type="entry name" value="Toluene_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018819" evidence="8">
        <location>
            <begin position="23"/>
            <end position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ40036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="511" mass="56188" checksum="D65B9C7E542A60B2" modified="2010-01-19" version="1">MNKKLLLLPSVISFIVSGTATAGGFQVNEHSATGLGRAFAGEAVIADNASVLARNPAAMAMFKRPAMSVGMTIIDTDVTVKNAQYQAPGANINANFDKESIFHFDGFAGFPGVDQDCKGQLCKRMAATAINGFLEKHGLETKIAWQDIPDHISVPKLPAIPEFDIYVPKYDSVDILPNTTFTPIADVSEIGPTEIVPNFYYIRPINDKWAVGIAAFSNFGTGTEFKSNYPASIFGGKTQVKSMNLGLSASYRINQYLSLGAGLDIIYGVGELYRDAGFDASLSASYNDKHYNLGKHHFGANVIDIDASGVAFGWNVGAVYELNANHRFGVSYRHSPDLKAKGDVMIAGKDHDEITVPLPDIAEFSGYHLLTDKFAMHYSVQWIGWRDFDQVSSKDLAIKEYEWKNSWHYALGGTYYLNDTWTLRAGYMFDKSPVDELKSISIPDSDRQWYSAGVTYHYTPNASFDFGAAYVRGEDVNVTEYLSPEMPELGAISAVTRANAFLMGVQFSYLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3X8</accession>
    <name>D0Z3X8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001131</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306297.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001131"/>
    <dbReference type="EnsemblBacteria" id="EEZ40109">
        <property type="protein sequence ID" value="EEZ40109"/>
        <property type="gene ID" value="VDA_001131"/>
    </dbReference>
    <dbReference type="GeneID" id="57343402"/>
    <dbReference type="eggNOG" id="COG0697">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1515911at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="181"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="210"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="241"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="265"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="3"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="151"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="296" mass="32380" checksum="E9117B549A10B02D" modified="2010-01-19" version="1">MFYLFPLLTVTIWAINAIVNKLSFSVIDPGAISFYRWFFAMVTLTPFVAIGAWRKRHIIKPYLSKLAFLALLGMVLNQSLGYFAAATTSATNMALIISLVPLISMFLSVPLLGQRLAPMALVGAVLSLAGLIFMLGHGDISYLLAQGITQGDGLLLIAAFVYALYSVLLKRWKMPISNWQSVYVQTLFAVIMLTPLLITSHRSGITADSLPLIMYAAIPASVIAPWCWLQAIERLGADRTAMFMNLMPVIAAIVASIVLHEQLAYYHYIGGMMVLAGVALAQRKPKQPPAKDMAIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3Y2</accession>
    <name>D0Z3Y2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001135</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306308.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40113">
        <property type="protein sequence ID" value="EEZ40113"/>
        <property type="gene ID" value="VDA_001135"/>
    </dbReference>
    <dbReference type="GeneID" id="57343397"/>
    <dbReference type="eggNOG" id="COG1284">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="86376at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021781">
        <property type="entry name" value="RctB_central_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040567">
        <property type="entry name" value="RctB_HTH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11826">
        <property type="entry name" value="DUF3346"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18622">
        <property type="entry name" value="HTH_55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_55" evidence="2">
        <location>
            <begin position="21"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3346" evidence="1">
        <location>
            <begin position="298"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="666" mass="75942" checksum="310AED54DDC541E7" modified="2010-01-19" version="1">MKTTQKTDTTTTEKILILAPRSHKDGHLFAIHSAIVDWLGQYQHFKGVTKSIIELLNLISLRGLSTVDGMVSTTELVEATEGQLTRAAIQQRLRAAVNLGLFTQQPVRFEEGLAGKTMLHHFVNPAHLISQLGTGSLISETSQEKEKKKRSKALAQTHVNRRLLTEHGLGTPPSMPDEADQIVVSPTSWAGIIDQALAPPRTKKSYQKSMVAISGTKAIIETRSSKSIMTVDDLMTLFALFTLTVQYHDHHISDYELQSRVMGNKTPVYITDILALRGKKDSGPARDSIRESIDRIEFTDFQLHELTGRWLSENMPEGFKSDRFRFIARTITASEEAPQEGEDGEIRIKPNLYIMVWEPSFFDELLTRDYFFLFPPEILRQHTLVFQLYTFFRSRMSRKGTDTMLLSELNQKLARNIEWRRFSVDLIRELRKLAKDKISESIFAVNLWGYHLTISPEDPDKRYTDYQIDIKCNADEVIRFSRAKTINEGKRNMAPTMPNPLRNEIMPRQHLDQLSEIIDGEFEPIQRKEHRPKGRLGRRIKLRKHLVEINADELTIILSKYTSPEALQRSITALSAMTGHPSSAITDECQGYLEKLDWLRVGDEVVSYETLSKTVELYNSQQDARHLSIERLISGLAVRRKVCKLVHTGHINDQVMAALDDVAKGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3Y3</accession>
    <name>D0Z3Y3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chromosome (Plasmid) partitioning protein ParA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001136</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306311.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001136"/>
    <dbReference type="EnsemblBacteria" id="EEZ40114">
        <property type="protein sequence ID" value="EEZ40114"/>
        <property type="gene ID" value="VDA_001136"/>
    </dbReference>
    <dbReference type="GeneID" id="57343396"/>
    <dbReference type="eggNOG" id="COG1192">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="729012at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025669">
        <property type="entry name" value="AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13614">
        <property type="entry name" value="AAA_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_31" evidence="1">
        <location>
            <begin position="109"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="404" mass="45954" checksum="11AA594B22E02581" modified="2010-01-19" version="1">MNREQTITNLLNIAEQTKQVQADRIEIVLEERREELFPPMSKALMETRSGLTRRKLDDAIARMEATGHQFTKNNANHYSITLDEAHKLMAAAKKPAFHEREGAGRKPWVVNVQNQKGGTGKSMTAVHLAACLALDLDKRYRICLIDLDPQGSLRLFLNPLISVGEQETIYSAVDVMLDNIPEGAQLNKKFLMDNVVLPTQYPNLKTIAAFPEDAMFNADAWQDLAVNQDLDIVRLLKDRVIDPIADEFDLIMIDTGPHIDPLVWNAMYASNALIIPCAAKRLDWASTVNFFQHLPTVYEMFPEDWHGLEFIRLMPTMFEDDNKKQVSVLTEMNYLLRDQVMMATVPRSRAFETCADTYSTVFDLTAAEFEGGKKTLSTAQEAIQRVSLELERVMHSHWANLNRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z423</accession>
    <name>D0Z423_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Electron transport protein hydN</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_000279</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303927.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000279"/>
    <dbReference type="EnsemblBacteria" id="EEZ39261">
        <property type="protein sequence ID" value="EEZ39261"/>
        <property type="gene ID" value="VDA_000279"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1142">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1762646at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12800">
        <property type="entry name" value="Fer4_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12838">
        <property type="entry name" value="Fer4_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="2"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="80"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="123"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="181" mass="19521" checksum="A652C78FF9ED5DAC" modified="2010-01-19" version="1">MNRFVFADPNLCIGCRTCEVACVISHQADSTVAGLNAVDFSPRLTLVKNAHVTTPVMCRQCDDAPCAQVCPNNAIVLEDGFVKVIQSRCIGCKTCVIACPYGAMNVVTKMVEETKGSALFKRQVPQSQALKCDLCNHREEGPACVQVCPTGAIRIIESETLTEDSKQKREAAALNAVAICR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z474</accession>
    <name>D0Z474_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">(GlcNAc)2 ABC transporter: substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000330</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304064.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000330"/>
    <dbReference type="EnsemblBacteria" id="EEZ39312">
        <property type="protein sequence ID" value="EEZ39312"/>
        <property type="gene ID" value="VDA_000330"/>
    </dbReference>
    <dbReference type="GeneID" id="57342523"/>
    <dbReference type="eggNOG" id="COG0747">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="162819at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030678">
        <property type="entry name" value="Peptide/Ni-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002741">
        <property type="entry name" value="MppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003020070" evidence="1">
        <location>
            <begin position="26"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="domain" description="SBP_bac_5" evidence="2">
        <location>
            <begin position="75"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="555" mass="63284" checksum="5AF353F7C33B3C9D" modified="2010-01-19" version="1">MLFNPKYTLTCLAISAAMATPTVMAQEKTQLTIVPDFYPTMIRNFNPFLSTNLRTTTDFIYEPLVIFNQMQENKPVMRLAKNYYMSEDLTQVTFEIRDGVKWSDGKPFTAADVVYSFNLIKAKPELDPRGINSWIKAIKQDGNKVIFDLTEANSNLPYEISAVPIVPQHIWQDIKNPENYANENPVGSGPFTEIDLFTPQLYVQCRNPHYWDNDNLDVDCLRAPQIANNDQLLSKIIKSELDWSSAFIPDIEATYVARNPHHKYWYPASTTQSFMLNFNTPKEGNHEAINNIDFRRAFSMAIDRQMIIDVAFYGNGVVNDYASGLGEVFKLWSDPETHNKYKQFNTYNVDNAKALLAKAGFKDLDGDGFVETPTGKKIELEVQSPNGWTDFNNTVQLGVEQLHAAGINAKARTPDFAVYNKAMVTGTYDVAYTNYFNGADPHRYWSSAYHSRYQVGDSMPRFAMHFFKNKELDTLIDSFYKTASVDEQKAISHKIQKIIAENQVTIPVMSGVDVYQFNESRFTGWWSAENPKGRPLAWAGVPERLLHVLDLKPRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4A6</accession>
    <name>D0Z4A6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sensory box/GGDEF family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000362</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304153.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000362"/>
    <dbReference type="EnsemblBacteria" id="EEZ39344">
        <property type="protein sequence ID" value="EEZ39344"/>
        <property type="gene ID" value="VDA_000362"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2199">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2200">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EAL" evidence="1">
        <location>
            <begin position="1"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="2">
        <location>
            <begin position="428"/>
            <end position="550"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="550" mass="63769" checksum="6F5FC6742B4CEA7F" modified="2010-01-19" version="1">MSPERRDFSFNYQPIYANNRIKSYEALLRLNDKNINIETFIQSIKNKPQFDLDVIRAVLFDIQDLNNTFTISINISILSLESDFFIRKALNILKNKNIILEITEHDKANNLDLIAYNIQLLKSETGVKFALDDFGRGYSNTESLMCLPVDIIKVDRSLVTNITDSYISYAVLKTKIGKILNILEKTVIVEGIETQTQLDLINLIGDCCIQGFYYSTPLERDVAFCHESKSIEFEPEHHVDFMQKLDKLIYDLTLNKNQVIDHNSFNNIFLHKENAVILDNAQSMIARLKEPTLLLLSSLIKDCECFIIIRDIKGTAIYNNENHVSYMRKDFVGIPVSEIYEQYPDYQYCIELDNKLLCSDSNFLISNESVCVDHNIECFQTFRQKIQYFDQTFIICTVYRDNNTLTMRRDALTGLYSREILSTPYANNYNRLIFIDLNGFKAINDKYGHGIGDLSLRQVSEILSENLRQDDLIIRHGGDEFVVLTMMYDEELINRRLNEINQLIVDTFSQQGLKLSFSFGISVVFESAQNAIVEADANMYKHKEYFKSKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4C7</accession>
    <name>D0Z4C7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Nickel/cobalt efflux system</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">VDA_000383</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Efflux system for nickel and cobalt.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the NiCoT transporter (TC 2.A.52) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000383"/>
    <dbReference type="EnsemblBacteria" id="EEZ39365">
        <property type="protein sequence ID" value="EEZ39365"/>
        <property type="gene ID" value="VDA_000383"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2215">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015099">
        <property type="term" value="F:nickel cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006824">
        <property type="term" value="P:cobalt ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011541">
        <property type="entry name" value="Ni/Co_transpt_high_affinity"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03824">
        <property type="entry name" value="NicO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0170">Cobalt</keyword>
    <keyword evidence="3" id="KW-0171">Cobalt transport</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0533">Nickel</keyword>
    <keyword evidence="8" id="KW-0921">Nickel transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="105"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="146"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="258"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="285"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="332"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ39365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="363" mass="38683" checksum="A40D1DF422E105F4" modified="2010-01-19" version="1">MEQIQTSSRKSSWLSIVVILGLIGLACYELWQVWPSLVLSSIKWQREINGQLSDLLYDAKNNSLAAGISLAGLSFIYGALHSLGPGHGKMIVTTYLATNPTKIKASLTMTIVSALMQAVVAVALVSILLAVFNASMRQISSQADQFILFSSFAVVALGAWVGLKAIKKLIQAKFSTPPEIKQQELADKSAPKFTISAIKPLQSSSSNSINAVNTKPTPALASTTFHTHQHDNNGVCGCGHKHVVSADEINNATTWKEYAGIIFSIGIRPCTGAVMVLLFANMVGIYWLGVVSAFVMALGTAMTTSIIAIMTITGKSLVKRYLNHNPNSNSQAGTWAQLIGGIILVLFGLLLVSSHSAGISPVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4T0</accession>
    <name>D0Z4T0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NERD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000163</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000163"/>
    <dbReference type="EnsemblBacteria" id="EEZ39147">
        <property type="protein sequence ID" value="EEZ39147"/>
        <property type="gene ID" value="VDA_000163"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0551">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011528">
        <property type="entry name" value="NERD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08378">
        <property type="entry name" value="NERD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50965">
        <property type="entry name" value="NERD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NERD" evidence="1">
        <location>
            <begin position="45"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="224" mass="24884" checksum="5A9F90662A37825E" modified="2010-01-19" version="1">MGLIIVIACAVFTTVFIVFWKSQENEQGEITNAPPSQKKSPSNQSGAEFEQELHDFVANILPSSGAVFDSLIIEDERGTTQIDLILILPSAFIVVEAKQMSGLIVGGQYNKRWMQFLAGGRSRFFFQNPFRQNYRHMKALESLTGVPIDTMGSAVVFGGRCTLGEKMPQLVFKDKESFGLYVQQLLPSPTLFTEEQIEFLCGKIAFAKQAGSQAQARHIQSLTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4X7</accession>
    <name>D0Z4X7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DNA-binding response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_000210</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306615.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000210"/>
    <dbReference type="EnsemblBacteria" id="EEZ39194">
        <property type="protein sequence ID" value="EEZ39194"/>
        <property type="gene ID" value="VDA_000210"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="817710at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="6"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="132"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="132"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ39194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="236" mass="27212" checksum="5E6B0A256B07CBDB" modified="2010-01-19" version="1">MTKTYSLLIIDNDLKLQQMLADYFRIQRFKVQTHSDSNGAIELIKSINPDIVLLDFISLCHDGLALCREIRRCYQGKLMILTASNDDFDHISALEIGVDDYVVKPIKQRVLLARMHILLRINELQPDTPSDINILNDGKLTLHKNRKLCELSGQKICMTDKEFDLLWLLANSPGTFLSRDFLTKELRGIEYNGIDRTVDNKIVSLRRKLLCYPSISQEIITIRGKGYLFVPDRRSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z556</accession>
    <name>D0Z556_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000106</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306865.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000004.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39090">
        <property type="protein sequence ID" value="EEZ39090"/>
        <property type="gene ID" value="VDA_000106"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1933795at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12844">
        <property type="entry name" value="HTH_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="27"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="121"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="208" mass="24584" checksum="DBDD0FFC3DCE097F" modified="2010-01-19" version="1">MKHKKKTMVKSSISHQILLMDWIYKKIAFIREQKKISALQMAKSINVTINTYVNIERGRCDIKLDNLILIAHYLDVCPSYLLNREHVSLSSYSTLELLIELSSREFNDHKVKTNFFMYDRLREIRQKKCFSQKYMTEVLNCSQDHYLKIESGKRSPRLNFYAKLVSELEIHPNFLIHGTSLSLSKYNELEIINELNSRYNHAYIVNAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z557</accession>
    <name>D0Z557_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hypothetical membrane spanning protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000107</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000107"/>
    <dbReference type="EnsemblBacteria" id="EEZ39091">
        <property type="protein sequence ID" value="EEZ39091"/>
        <property type="gene ID" value="VDA_000107"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2199">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="381"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="2">
        <location>
            <begin position="431"/>
            <end position="557"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="559" mass="65501" checksum="0FDD3F8B920C69F2" modified="2010-01-19" version="1">MMNYIKIPLFIFLVFIAFFSKDQNIIKRNISFENRKELIELQGYCSKEECRIINNFLMLPIEKYPSEYKAIAEDIRNILHTKQGARIGSYILETMNNYFDENIDAKMYLLLKISTLKRLSDDLYGMLIPTIEFLSLAKKSGDEYMISVGTVNLASILNFFDGYHTSNQLLNAVPISNFSDNKWNRLRIRSQLIIAENNIAIGDYNKSSKILKNIITQDNGIPSNEWDDYHSYILALQADIAMHFNRDDEARKYLDQANSLLNQDDYNFLVDKHTVIKTIELKWAIKNNINVYAKLNDMKFYHDNSAIISSRYLKMLYESIFDYYFESNDHTKYHELRKEYLSKIEYRMKLSYKLLYNNSIINVNNDLLIDERDNLITKLKYSLAIILVITLILILVFIKYILINSENLNDELTKIGNRKKYNRDIKKLGFNVYYLVLIDIDNFKLINDRYGHDVGDYVLKKLSNVISHLLPNNSEIYRIGGEEFAIIFRGCHPQNIVDIMNHIRINVENLSWNSIDKVTISIGIARSDNSKDVYKKADELLYLSKTSGKNQLSIEEDYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z566</accession>
    <name>D0Z566_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hypothetical intracellular protease/amidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000116</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306894.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000116"/>
    <dbReference type="EnsemblBacteria" id="EEZ39100">
        <property type="protein sequence ID" value="EEZ39100"/>
        <property type="gene ID" value="VDA_000116"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0693">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1421548at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DJ-1_PfpI" evidence="1">
        <location>
            <begin position="2"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="198" mass="21937" checksum="BFF633896BB4586F" modified="2010-01-19" version="1">MKKVILFLCQGLEEYEASVFTDAFGWTTTYGIEPIELITVGLRPKVKCAWNFTIKPEYQLSEIDINDFDALAIPGGMSRSGFYEDAYDERLLSLIRDFDSKGKIIASVCVGALPIAKSGVLNGRNGTTYHLSKKRQTQMEEMGVNVIQAPIVIDKNIITSRSPSAAMDVAFKVVEMLTSTANLKHIKEGMGFIEKTDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z591</accession>
    <name>D0Z591_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Peyer's patch-specific virulence factor GipA (Transposase)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">VDA_000141</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the transposase 35 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the N-terminal section; belongs to the transposase 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306966.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000004.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39125">
        <property type="protein sequence ID" value="EEZ39125"/>
        <property type="gene ID" value="VDA_000141"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0675">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="222391at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032196">
        <property type="term" value="P:transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001959">
        <property type="entry name" value="Transposase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010095">
        <property type="entry name" value="Transposase_IS605_OrfB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021027">
        <property type="entry name" value="Transposase_put_HTH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12323">
        <property type="entry name" value="HTH_OrfB_IS605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01385">
        <property type="entry name" value="OrfB_IS605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07282">
        <property type="entry name" value="OrfB_Zn_ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01766">
        <property type="entry name" value="tspaseT_teng_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0815">Transposition</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="HTH_OrfB_IS605" evidence="13">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="domain" description="OrfB_IS605" evidence="11">
        <location>
            <begin position="165"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="OrfB_Zn_ribbon" evidence="12">
        <location>
            <begin position="289"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF07282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF12323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEZ39125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="365" mass="41678" checksum="ABCB066B10435B34" modified="2010-01-19" version="1">MTLRAYKYRFYPNADQARMLNQTFGCTRFVYNNALAYSKEQYELGNKTNFNDWSKNLTILKKNPDFVWLKDVASVPLQQSLKHLDKAFKSFFKSGFGYPKFKNKRGKQSACYVGTAFRFNRDKCEIELAKMKQPLKIKWSRSFVGIPSSVYVSKTKTGKYFISILVEEEIIQNKPTDKTVGIDLGIKSLAVCSDGVTFDNPKSTAKYAKKLAKEQRKLSKKKKGSSNFSKQRIKVAKIHEKIANVRMDFTHKMTTRLINENQVIGIESLKVKNMIKNKKLSKALSDANFGEIVRQLEYKANWYGRTVSAISQWFPSSKMCSACGCLFSGKWSLGIREWTCDCGSLNDRDINAAINIHAEGLRLIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5B6</accession>
    <name>D0Z5B6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000023</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000005">
        <property type="protein sequence ID" value="EEZ39038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005307047.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000005.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39038">
        <property type="protein sequence ID" value="EEZ39038"/>
        <property type="gene ID" value="VDA_000023"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031PG0">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019450" evidence="1">
        <location>
            <begin position="18"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="295" mass="32033" checksum="2D5A47D1DA13B36D" modified="2010-01-19" version="1">MKILLIALYLFPSLAFSATVTISRGDTYTAVIPISVNKTNIYPYSNNRHAGLCVGFGMNSGYYCELRKTYDKDGIHLSIDNANGQIESTLSGLVTLTIDNGIATCGPDSKGCGIGSPWPIYSIFREQFTNNPSTPYNASINLNTVKISSAKDAIPGKHIVPVGVAVIERGYGWRVTNKNLEVVVRDVTCTLSDNSINIGTIVPGQSVTKKINLKPTCDSFLAGASWRYSNLYGNENTNLDNVSIKVKNDKNEIVNSDTPYTNVNELNDLSVEVNAKSNAEGGKLNVPLRFTLTYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5D0</accession>
    <name>D0Z5D0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type IV secretory pathway VirB4 component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000037</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000005">
        <property type="protein sequence ID" value="EEZ39052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000037"/>
    <dbReference type="EnsemblBacteria" id="EEZ39052">
        <property type="protein sequence ID" value="EEZ39052"/>
        <property type="gene ID" value="VDA_000037"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3451">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043964">
        <property type="entry name" value="P-loop_TraG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19044">
        <property type="entry name" value="P-loop_TraG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="P-loop_TraG" evidence="1">
        <location>
            <begin position="82"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF19044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="341" mass="38342" checksum="D0CE43B657D8FF65" modified="2010-01-19" version="1">MRSKKAGGQLGDGRNDGTQDHPLAILLDDITGLIAAMAAPNTDLDDTLESALSDAILMAWESNKQNTLIDHVQDALFTLSEEREDKRIRDFGYQLNKFCQDGIYGDIFNKRSQLDPNVHLTTIELDGFSDNLLQPVMFALMVSINQAMYLAGSRSVPKMCIIEEAWKLMSGSNRQARAFIDKGYRTARKFGGGFTTVTQGIVDFFASPEATSAYNNSDIKLILRQGDGFDKFIKENPEAFDPMHVNLIKRFPPAGQTGFSCSMLQAGPNITFHRLFVDPWTLSLYSTHPKEYEYCETLLSNGTPLMDAINQTAWHFYGDNMKHFEDIKAQYLLDKQSQEMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVM4</accession>
    <name>D0YVM4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GGDEF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001593</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298340.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001593"/>
    <dbReference type="EnsemblBacteria" id="EEZ40566">
        <property type="protein sequence ID" value="EEZ40566"/>
        <property type="gene ID" value="VDA_001593"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3706">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GGDEF" evidence="2">
        <location>
            <begin position="399"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="160"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="333"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="538" mass="62279" checksum="A4CB4D60232299D6" modified="2010-01-19" version="1">MEHPETFYAEIIKQWGHAHSLRTLCELTCRNLEQSFGVLACELVVSYKNSWTSLVVMDETGIHYHFPPQDLQNDGAIPFYRINKSLRQNTPVRHVQDNELYISLPLERRSRIIGCFIMKFDLAKSSALEASSFAPLAALLSAEVHASFVSESMIDELWGRRTAERELQITQDEQKELMEQLQALHDLSYMLWRAESMDAMLFTAVEQSKKLLHIDRLAIFLFDDNYRMHGTYGSDLQGKTVDEHYFESEIPDLWFASHTLAKREYTAIQEHTELYHDLKQVGYGWSGYIALWDDDTPVGWIACDNLVTGSPLRQYHNHIFQQLGFIISQHIVRRQAEEELMKLNKELEQRVHERTTELEQVNQQLEKMSRQDPLTQVANRRVFDNTFDEEWRRAERHQLPISLLIIDVDHFKHYNDCFGHAAGDACLRKIAKALNTIERRAGALFARYGGEEFVLLLPGQELSAATYTAKRVIHEVHKLALPTNKTAEYGDIKDVVTVSIGVHCQIPHAATSMEEFFRQTDIALYEAKSRGRDQYFVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVQ0</accession>
    <name>D0YVQ0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">3-methyl-2-oxobutanoate hydroxymethyltransferase</fullName>
            <ecNumber evidence="5">2.1.2.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Ketopantoate hydroxymethyltransferase</fullName>
            <shortName evidence="5">KPHMT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">panB</name>
        <name evidence="9" type="ORF">VDA_001215</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + 3-methyl-2-oxobutanoate + H2O = (6S)-5,6,7,8-tetrahydrofolate + 2-dehydropantoate</text>
            <dbReference type="Rhea" id="RHEA:11824"/>
            <dbReference type="ChEBI" id="CHEBI:11561"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="EC" id="2.1.2.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5 8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="5 8">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; (R)-pantothenate biosynthesis; (R)-pantoate from 3-methyl-2-oxobutanoate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 5">Homodecamer; pentamer of dimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the PanB family.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.11" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297653.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001215"/>
    <dbReference type="EnsemblBacteria" id="EEZ40193">
        <property type="protein sequence ID" value="EEZ40193"/>
        <property type="gene ID" value="VDA_001215"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0413">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="916845at2"/>
    <dbReference type="UniPathway" id="UPA00028">
        <property type="reaction ID" value="UER00003"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003864">
        <property type="term" value="F:3-methyl-2-oxobutanoate hydroxymethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06557">
        <property type="entry name" value="KPHMT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00156">
        <property type="entry name" value="PanB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003700">
        <property type="entry name" value="Pantoate_hydroxy_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20881">
        <property type="entry name" value="PTHR20881"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02548">
        <property type="entry name" value="Pantoate_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000388">
        <property type="entry name" value="Pantoate_hydroxy_MeTrfase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00222">
        <property type="entry name" value="panB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3 5" id="KW-0566">Pantothenate biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 9" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Alpha-ketoisovalerate binding" evidence="5 7">
        <location>
            <begin position="45"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5 6">
        <location>
            <position position="181"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 8">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 7 8">
        <location>
            <position position="84"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>3-methyl-2-oxobutanoate</name>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 8">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000388-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000388-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000388-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ40193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="264" mass="28722" checksum="3A7A1FAAD01305CC" modified="2010-01-19" version="1">MKKITINDLMTWKREGRKFASITAYDASFAQLFEQQEVPVLLVGDSLGMVLQGKPDTLPVTVEDIAYHTRCVRAGNQNSLLMADMPFMSYGTPEQACDNAAQLMRAGANMVKLEGGAWLAETITKLTERAIPVCAHLGLTPQSVNIFGGFKVQGRDADRAEQMVKDAILLQRAGAQVILLECVPVSLAERITNAVDVPVIGIGAGNVTDGQILVMHDVFGISANYIPKFSKNYLAETGDVRAAVRKFLEEVESGAFPDAQRTFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVX1</accession>
    <name>D0YVX1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001252</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001252"/>
    <dbReference type="EnsemblBacteria" id="EEZ40230">
        <property type="protein sequence ID" value="EEZ40230"/>
        <property type="gene ID" value="VDA_001252"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2991">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007495">
        <property type="entry name" value="NqrM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40691">
        <property type="entry name" value="PTHR40691"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04400">
        <property type="entry name" value="NqrM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="48" mass="5191" checksum="505CC6DD0346D79F" modified="2010-01-19" version="1">MAIGWILKKKTIAGSCGGLAGVGIEKECDCDKPCDEHKLYQIQEPGQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW41</accession>
    <name>D0YW41_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ribosome hibernation protein YfiA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001321</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297857.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001321"/>
    <dbReference type="EnsemblBacteria" id="EEZ40296">
        <property type="protein sequence ID" value="EEZ40296"/>
        <property type="gene ID" value="VDA_001321"/>
    </dbReference>
    <dbReference type="GeneID" id="57339786"/>
    <dbReference type="eggNOG" id="COG1544">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2088581at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044238">
        <property type="term" value="P:primary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00552">
        <property type="entry name" value="RaiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036567">
        <property type="entry name" value="RHF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003489">
        <property type="entry name" value="RHF/RaiA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02482">
        <property type="entry name" value="Ribosomal_S30AE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69754">
        <property type="entry name" value="SSF69754"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00741">
        <property type="entry name" value="yfiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0810">Translation regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="86"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="119" mass="13676" checksum="5B361E9E01779424" modified="2010-01-19" version="1">MTLEITGKNIDVTPAIRERFEFKFNKLEKFQVPFIKKHVVIGQEPNKLFKVEVTTAIPGGQLVASAEHEDLFGAITEVYQKLERQLKKQAHKPTARRASHSEKPELAEEEVDLTEEFEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW76</accession>
    <name>D0YW76_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ribosome-recycling factor</fullName>
            <shortName evidence="3">RRF</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Ribosome-releasing factor</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">frr</name>
        <name evidence="5" type="ORF">VDA_001361</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the RRF family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297920.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001361"/>
    <dbReference type="EnsemblBacteria" id="EEZ40336">
        <property type="protein sequence ID" value="EEZ40336"/>
        <property type="gene ID" value="VDA_001361"/>
    </dbReference>
    <dbReference type="GeneID" id="57339730"/>
    <dbReference type="eggNOG" id="COG0233">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1674344at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006415">
        <property type="term" value="P:translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00520">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00040">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002661">
        <property type="entry name" value="Ribosome_recyc_fac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023584">
        <property type="entry name" value="Ribosome_recyc_fac_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036191">
        <property type="entry name" value="RRF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20982">
        <property type="entry name" value="PTHR20982"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01765">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55194">
        <property type="entry name" value="SSF55194"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00496">
        <property type="entry name" value="frr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RRF" evidence="4">
        <location>
            <begin position="20"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="185" mass="20766" checksum="BAFF0892836BF0EE" modified="2010-01-19" version="1">MINEIKQDAKTRMEKSVDALKSQLAKVRTGRAHPSLLDTIYVEYYGANTPLNQVANVVAEDSRTLAITVFDRELAPKVEKAIMMSDLGLNPMSAGTVIRVPLPALTEERRRDLVKIVRAEAEQGRVAVRNIRRDANANVKALLKDKEISEDDDRRAQDEIQKLTDDAIKSIEAVLEVKEKELMEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWA0</accession>
    <name>D0YWA0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cell division protein FtsQ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ftsQ</name>
        <name evidence="10" type="ORF">VDA_001178</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Part of a complex composed of FtsB, FtsL and FtsQ.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell inner membrane</location>
            <topology evidence="8">Single-pass type II membrane protein</topology>
        </subcellularLocation>
        <text evidence="8">Localizes to the division septum.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the FtsQ/DivIB family. FtsQ subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297580.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001178"/>
    <dbReference type="EnsemblBacteria" id="EEZ40156">
        <property type="protein sequence ID" value="EEZ40156"/>
        <property type="gene ID" value="VDA_001178"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1589">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1270665at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090529">
        <property type="term" value="P:cell septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043093">
        <property type="term" value="P:FtsZ-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11690">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00911">
        <property type="entry name" value="FtsQ_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005548">
        <property type="entry name" value="Cell_div_FtsQ/DivIB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026579">
        <property type="entry name" value="FtsQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045335">
        <property type="entry name" value="FtsQ_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034746">
        <property type="entry name" value="POTRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013685">
        <property type="entry name" value="POTRA_FtsQ_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35851">
        <property type="entry name" value="PTHR35851"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03799">
        <property type="entry name" value="FtsQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08478">
        <property type="entry name" value="POTRA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51779">
        <property type="entry name" value="POTRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 8 10" id="KW-0132">Cell division</keyword>
    <keyword evidence="2 8" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="domain" description="POTRA" evidence="9">
        <location>
            <begin position="51"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ40156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="263" mass="29991" checksum="62B6C6C357380BB2" modified="2010-01-19" version="1">MTAAVVKRISLKSPKTLLKRFGGLAFFISVIAFTIWLVTATKDWMTDANRLPLSQLVVQGDLKYLTNNDVREAILQMGHMGSFMTQNVDSLQHAVEEQPWVEQATVRKQWPDTIKTFVIERQPAAEWDGKYLVDEHGVVFKALASTIKDKTLVDLVGPEGSSEEMLAGLREMQPELQHAGFDVVKISLNKRRAWQILLSNGIQLKLGREARMERLERFIRLYPTIEKQGKDIEYIDLRYDTGAAVGWKMTSDQESPKRNESVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWJ7</accession>
    <name>D0YWJ7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Probable Fe(2+)-trafficking protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001222</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the Fe(2+)-trafficking protein family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297669.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001222"/>
    <dbReference type="EnsemblBacteria" id="EEZ40200">
        <property type="protein sequence ID" value="EEZ40200"/>
        <property type="gene ID" value="VDA_001222"/>
    </dbReference>
    <dbReference type="GeneID" id="57339902"/>
    <dbReference type="eggNOG" id="COG2924">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2038019at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3880.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00686">
        <property type="entry name" value="Fe_traffic_YggX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007457">
        <property type="entry name" value="Fe_traffick_prot_YggX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036766">
        <property type="entry name" value="Fe_traffick_prot_YggX_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36965">
        <property type="entry name" value="PTHR36965"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04362">
        <property type="entry name" value="Iron_traffic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029827">
        <property type="entry name" value="Fe_traffic_YggX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111148">
        <property type="entry name" value="SSF111148"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="90" mass="10574" checksum="3D172D24DA66FAC5" modified="2010-01-19" version="1">MSRTVFCTRLQKEADGLDFQFYPGEIGKRIFDNISKEAWAQWQAKQTMLINEKKLNMMNPEHRQLLETEMVNFLFEGKDVVIDGYTPPSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWT5</accession>
    <name>D0YWT5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Formate efflux transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_001480</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FNT transporter (TC 2.A.44) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001480"/>
    <dbReference type="EnsemblBacteria" id="EEZ40454">
        <property type="protein sequence ID" value="EEZ40454"/>
        <property type="gene ID" value="VDA_001480"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2116">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015499">
        <property type="term" value="F:formate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000292">
        <property type="entry name" value="For/NO2_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024002">
        <property type="entry name" value="For/NO2_transpt_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023999">
        <property type="entry name" value="Formate_transptr_FocA_put"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30520">
        <property type="entry name" value="PTHR30520"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01226">
        <property type="entry name" value="Form_Nir_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00790">
        <property type="entry name" value="fnt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04060">
        <property type="entry name" value="formate_focA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01005">
        <property type="entry name" value="FORMATE_NITRITE_TP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01006">
        <property type="entry name" value="FORMATE_NITRITE_TP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="25"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="63"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="154"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="185"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="245"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="279" mass="30314" checksum="704A0597585E483E" modified="2010-01-19" version="1">MPPAMAHKAEEVGVYKATKHPLQSFYLAITAGVFISIAFVFYTTVTTGAGDVAWGLSKFAGGLAFSLGLVLVVICGGELFTSSVLTTVARASGRITTMQLLRNWVIVYAGNFVGAIFFVACIWIAQQHMAGNGQWGINAMKIAQHKLHHTFGQAVMLGILCNLMVCLAVWMTFSCRSATDKVMVMILPVAMFVASGFEHCIANMFMIPMGIVIHAFASPEFWSMTGVDPSQFADLTVSHFVMNNLIPVTIGNIIGGGFFVGMTYWIIHRRPELKGQGHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWT8</accession>
    <name>D0YWT8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transglycosylase associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_001483</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0410 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298135.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40457">
        <property type="protein sequence ID" value="EEZ40457"/>
        <property type="gene ID" value="VDA_001483"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2261">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2084822at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007341">
        <property type="entry name" value="Transgly_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33884">
        <property type="entry name" value="PTHR33884"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04226">
        <property type="entry name" value="Transgly_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ40457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="82" mass="8423" checksum="BD09CF2B3E096176" modified="2010-01-19" version="1">MGIISWIILGLIAGALAKWLMPGQDGGGWIATMGLGIAGAFAGGWLGSFIGLGNATGVNIPSIVTATLGAFILLFIYNRFIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWW7</accession>
    <name>D0YWW7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">3-phosphoshikimate 1-carboxyvinyltransferase</fullName>
            <ecNumber evidence="7">2.5.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">5-enolpyruvylshikimate-3-phosphate synthase</fullName>
            <shortName evidence="7">EPSP synthase</shortName>
            <shortName evidence="7">EPSPS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">aroA</name>
        <name evidence="9" type="ORF">VDA_001800</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>3-phosphoshikimate + phosphoenolpyruvate = 5-O-(1-carboxyvinyl)-3-phosphoshikimate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21256"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57701"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
            <dbReference type="EC" id="2.5.1.19"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the EPSP synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.19" evidence="7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298725.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001800"/>
    <dbReference type="EnsemblBacteria" id="EEZ40768">
        <property type="protein sequence ID" value="EEZ40768"/>
        <property type="gene ID" value="VDA_001800"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0128">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="533829at2"/>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00089"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003866">
        <property type="term" value="F:3-phosphoshikimate 1-carboxyvinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01556">
        <property type="entry name" value="EPSP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.65.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00210">
        <property type="entry name" value="EPSP_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001986">
        <property type="entry name" value="Enolpyruvate_Tfrase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036968">
        <property type="entry name" value="Enolpyruvate_Tfrase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006264">
        <property type="entry name" value="EPSP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023193">
        <property type="entry name" value="EPSP_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013792">
        <property type="entry name" value="RNA3'P_cycl/enolpyr_Trfase_a/b"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00275">
        <property type="entry name" value="EPSP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000505">
        <property type="entry name" value="EPSPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55205">
        <property type="entry name" value="SSF55205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01356">
        <property type="entry name" value="aroA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00104">
        <property type="entry name" value="EPSP_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00885">
        <property type="entry name" value="EPSP_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 7" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="EPSP_synthase" evidence="8">
        <location>
            <begin position="7"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Shikimate-3-phosphate binding" evidence="7">
        <location>
            <begin position="22"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphoenolpyruvate" evidence="7">
        <location>
            <begin position="94"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Shikimate-3-phosphate binding" evidence="7">
        <location>
            <begin position="170"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="314"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="342"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>3-phosphoshikimate</name>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>3-phosphoshikimate</name>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="337"/>
        </location>
        <ligand>
            <name>3-phosphoshikimate</name>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="341"/>
        </location>
        <ligand>
            <name>3-phosphoshikimate</name>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="345"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="387"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="412"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ40768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="426" mass="46188" checksum="6746BB9F3E46A7A7" modified="2010-01-19" version="1">MESLTLQPINLINGEVNLPGSKSVSNRALLLAALAQGTTRLTNLLDSDDIRHMLNALQQLGVQYQLSADKTECTVEGLGQPFSVKDFTCLYLGNAGTAMRPLAAALCLGQGEFELTGEPRMKERPIGHLVDALRSAGADITYLENEHYPPLKIKGTGLDGGEVSIDGSISSQFLTAFLMAAPLAKSDTTILIKGDLVSKPYIDITLNIMAQFGVQVENQNYQKFIVPAGQVYQSPGEFLVEGDASSASYFLAAGAIKGGEVKVTGIGKNSIQGDIQFADALEAMGAEIEWGEDYIIARHRQLNAIDMDFNHIPDAAMTIATAALFAPGTTSIRNVYNWRVKETDRLHAMATELRKLGADVEEGDDYITITPPTQLKHAAIDTYDDHRMAMCFSLVALSDTAVTINDPKCTSKTFPDYFIKLEQLSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX15</accession>
    <name>D0YX15_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002068</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299335.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002068"/>
    <dbReference type="EnsemblBacteria" id="EEZ41036">
        <property type="protein sequence ID" value="EEZ41036"/>
        <property type="gene ID" value="VDA_002068"/>
    </dbReference>
    <dbReference type="GeneID" id="57341820"/>
    <dbReference type="eggNOG" id="ENOG502ZSMJ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1317643at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021398">
        <property type="entry name" value="DUF3037"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11236">
        <property type="entry name" value="DUF3037"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="281" mass="32254" checksum="85FA991A81066DE2" modified="2010-01-19" version="1">MKKLVRYSVIRFMPFSETQEFANVGIVIHAPQTGEVQFKLANTRFGRVSQFFDDLDGQLYANAIKMFNVELQRIQEFTQGMTGKALASFMDEVTRPKEGFLTYSETAALLTTDSLTIVLETLFQQYVGRSFNTKEHREILLVKSLKKQLDQVSKYKFTKSKLSTDYMAFELPLVATDNIETKAIKPLSFFQETPLKLIDHGEFWISRVKHLLNSDTIDANNFLFAVERPDFKNKNLDAAFGSLTEEMNTLGVKVYDIKDINSIERFARFNSENAANFQLVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX50</accession>
    <name>D0YX50_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Methyl-accepting chemotaxis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_001844</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the methyl-accepting chemotaxis (MCP) protein family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001844"/>
    <dbReference type="EnsemblBacteria" id="EEZ40812">
        <property type="protein sequence ID" value="EEZ40812"/>
        <property type="gene ID" value="VDA_001844"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0840">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="429006at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0807">Transducer</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="315"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="338"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="6">
        <location>
            <begin position="395"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="7">
        <location>
            <begin position="582"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="575"/>
            <end position="615"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00029447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ40812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="667" mass="74326" checksum="467B9554E3BB4B26" modified="2010-01-19" version="1">MKTHRLPSVIHRMYFSFAVMVALLIFTVILLLSGSNKIHSQLNTLAANALPLVSASNHTSVSLLAADKVFKDFLTSQDISAMSQYQHNFKQAEQDYLHAQQQLADIIIRHPDLASNMEQLFQLQQSYFQEAEIAMNNYRTQLLAQTERQQSTRRFQRLHAKLNSGIKDEVAKQQNFSVKMLAKNYFEKLSETETVTSDALASENIAAIDQAVKANRKSVNHLGFAYRGITTQLPDLKPIFDKDVEQYIQDIGRSGGVLDQHFEYITAKDRLYTNIATLAQQIDQAMALLLQFDQKASHLMNQSISNADTVYQQGLYRALLLGTVVILFAIFIGWRLAHSVRQPLRATLNTLQALADGNMTQRIPNSKYHEFNQLSQFVNTVANNLQDILGKINEASDSLTNVSIQNHHLTEQAQQKLNEQRQQTASVATAMTEMEQSVAEVTMSAQHTQQKVHDVENASITGRDVMSQNIHSAHELSARLDESVQAVQQLKSMSNNIGSILDVIRNIADQTNLLALNAAIEAAQAGEQGRGFAVVADEVRVLAKRTTESTTEIETMIHSLQQSSNQATTMMQACVSEMNNNIEQASDANSAMEEIQALVIEISQMSSQIAQAAEEQRCTTSDIARNLEDISLIADSNSQAMTDISLSSHQLESLAQTQQQLVTRFTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX73</accession>
    <name>D0YX73_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transcription-repair-coupling factor</fullName>
            <shortName evidence="8">TRCF</shortName>
            <ecNumber evidence="8">3.6.4.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">mfd</name>
        <name evidence="11" type="ORF">VDA_001857</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">In the C-terminal section; belongs to the helicase family. RecG subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">In the N-terminal section; belongs to the UvrB family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001857"/>
    <dbReference type="EnsemblBacteria" id="EEZ40825">
        <property type="protein sequence ID" value="EEZ40825"/>
        <property type="gene ID" value="VDA_001857"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000716">
        <property type="term" value="P:transcription-coupled nucleotide-excision repair, DNA damage recognition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00969">
        <property type="entry name" value="TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036101">
        <property type="entry name" value="CarD-like/TRCF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003711">
        <property type="entry name" value="CarD-like/TRCF_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004576">
        <property type="entry name" value="Mfd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037235">
        <property type="entry name" value="TRCF-like_C_D7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005118">
        <property type="entry name" value="TRCF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041471">
        <property type="entry name" value="UvrB_inter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02559">
        <property type="entry name" value="CarD_CdnL_TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03461">
        <property type="entry name" value="TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17757">
        <property type="entry name" value="UvrB_inter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01058">
        <property type="entry name" value="CarD_TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00982">
        <property type="entry name" value="TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141259">
        <property type="entry name" value="SSF141259"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143517">
        <property type="entry name" value="SSF143517"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00580">
        <property type="entry name" value="mfd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="622"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="805"/>
            <end position="958"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ40825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="1153" mass="130862" checksum="00C6AB38F59862B8" modified="2010-01-19" version="1">MMKQNTILSIPLPKKAGESSYVGNLSGAALALSIAELAANHNGPILAVVPDSQTAVRLQPEISQFTHTDVTIFPDWETLPYDNFSPHQDIISDRLARLYQLPTQESGVLLVPISTLLQRLTPREYLHQHALIVKKGDRLSLEKLRLQLEASGYRHVDQVIEHGEYASRGSLLDLYPMGSNHPYRIDFFDDEVDSIREFDPENQRSTGEIEHINLLPAHEFPTDDLAVESFRVRWRERFEARREPESIYQQVSKKTWPAGIEYWQPLFFDHTESLFDYLPQQTLLVTLGELEPAVDQFLADADYRYDQRRVDPLRPLLEPKELWLTKDEMHIGFKQLPRVRVQQESVDIDKADRFNPALTKLPELTINHQLKEPLAELRRFTEQFTGKVIFSVASEGRREALLDLLARIKLRPMVCANLTEAVESPSNYTMVIGAAENGFLLSDPHVAFICESDLLGERVTQRRRREEKRTTVNADTIIRNLAELQIDQPVVHIEHGIGRYKGLQTLEAGGITTEYVTLEYQNSAKLYVPVASLHLISRYSGGAEETAPIHKLGGEAWAKARKKAAEKVRDVAAELLDVYAKRELKPGFKFKLDREAYADFCTGFPFEETHDQALAINMVLSDMCQTKVMDRLVCGDVGFGKTEVAMRAAFVAVDNNKQVTVLVPTTLLAQQHFENFRDRFANTPIRVEVLSRFKTAKEQKQILADVEEGKIDILIGTHKLLNSTVKYHDLGLLIVDEEHRFGVRQKEKIKAIRANVDILTLTATPIPRTLNMAMSGMRDLSIIATPPARRLAIKTFVREKDDAIVREAILREINRGGQVYFLHNEVDTIEKTVEDISKLVPEARITFAHGQMRERELERIMSDFYHQRFNVLVCTTIIETGIDVPTANTIIMDRADNLGLAQLHQLRGRVGRSHHQAYAYLLTPHPKRMTKDAVKRLEAIASLEDLGAGFTLATHDLEIRGAGELLGDEQSGQIQSVGFTLFMEMLEQAVDALKEGKEPSLDDLLKEQTEVELRMPALLPDDFMPDINTRLSMYKRIASAKDQTELDEIRVELIDRFGLLPEATKNLLALNQIKLKAAKIGIRKIEAGEKGGYFEFSQDANINPAILVNLLQTQPQYYRMEGPTKLKIFLTDSDRQKRIKFVNDLVDQLSQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXB3</accession>
    <name>D0YXB3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Transport ATP-binding protein CydD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_001653</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298450.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001653"/>
    <dbReference type="EnsemblBacteria" id="EEZ40626">
        <property type="protein sequence ID" value="EEZ40626"/>
        <property type="gene ID" value="VDA_001653"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4988">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="643917at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042883">
        <property type="term" value="P:cysteine transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014216">
        <property type="entry name" value="ABC_transptr_CydD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02857">
        <property type="entry name" value="CydD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="23"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="62"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="245"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="278"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="26"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="350"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="383"/>
            <end position="390"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ40626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="593" mass="65441" checksum="7213D8BACB833650" modified="2010-01-19" version="1">MDKQLQRDLTKWLKSQSKLAKRWLMLSVGLGFVSGLLLIGQAALLASILHQLIIEHVDKHQLISQFIGLAVVIGLRALCSWGREICGYRCGEQIRLHIRQLIIQRLQNLGPAYIKGKPAGTWASLVLEQVEEMQDFFARYIPQMSIAVLVPFIILVAVFPMNWAAGLIFLGTAPLVPLFMALVGLGAADANRRNFKALQRLSGHFYDRLKGLQTIRLFNRAEAEAENLDVASQILRKRTMEVLRLAFLSSAVLEFFSAISVAIVAVYFGFAFIGELNFGNYGAPITLFTGLFVLVLAPEFYQPLRDLGTFYHAKAQAIGAAESIVEFLNLEADEMNQGSENLPSPEAITIKARDLEVLSPEGQVLAGPISFTINQQEHVALIGPSGAGKTSLLNALLGFLPYRGQLTINGIELKALDQQQWRQTISWVGQNPLLFHGSIRDNIALGNPLATDANIAQVAKEAYADEFISRLEHGYQHHVGDRSGGLSVGQAQRIAVARAMLQNGAFWLLDEPTASLDANSEHLVLQSLTRAINKQTTLMVSHRLDQLHSMDRVLVMEHGKLVQNGAFDEIKHQGLLAEMLAYSKQINQGDLDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXB4</accession>
    <name>D0YXB4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Thioredoxin reductase</fullName>
            <ecNumber evidence="4">1.8.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_001654</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>[thioredoxin]-dithiol + NADP(+) = [thioredoxin]-disulfide + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:20345"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.8.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="5">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.9" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298453.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001654"/>
    <dbReference type="EnsemblBacteria" id="EEZ40627">
        <property type="protein sequence ID" value="EEZ40627"/>
        <property type="gene ID" value="VDA_001654"/>
    </dbReference>
    <dbReference type="GeneID" id="57342263"/>
    <dbReference type="eggNOG" id="COG0492">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="692968at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004791">
        <property type="term" value="F:thioredoxin-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019430">
        <property type="term" value="P:removal of superoxide radicals"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008255">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_2_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005982">
        <property type="entry name" value="Thioredox_Rdtase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01292">
        <property type="entry name" value="TRX_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00573">
        <property type="entry name" value="PYRIDINE_REDOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="4 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 4" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="6">
        <location>
            <begin position="9"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="319" mass="34554" checksum="5B77E247419841CC" modified="2010-01-19" version="1">MSNVRHCNLLILGSGPAGYTAAVYAARANLKPVMITGMQQGGQLTTTTEIENWPGDAGDLTGPALMDRMKEHAEKFETEIIFDHIHSTDFSQRPFRLNGDMGEYTCDALIICTGASAKYIGLESEEAFKGKGVSACATCDGFFYRNQKVAVVGGGNTAVEEALYLSNIASEVHLIHRRDTFRSEKILIDRLMDKVENGNIILHTDRTLDEVLGDQMGVTGVRLKDTQSDNTEELDVMGVFIAIGHQPNTAIFADQLAMENGYIKVQSGLTGNATQTSVEGIFAAGDVMDHIYRQAITSAGTGCMAALDAERYLDALAQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXC5</accession>
    <name>D0YXC5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Iron-sulfur cluster carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001665</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Mrp/NBP35 ATP-binding proteins family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298475.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001665"/>
    <dbReference type="EnsemblBacteria" id="EEZ40638">
        <property type="protein sequence ID" value="EEZ40638"/>
        <property type="gene ID" value="VDA_001665"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0489">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140663">
        <property type="term" value="F:ATP-dependent FeS chaperone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02040">
        <property type="entry name" value="Mrp_NBP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019591">
        <property type="entry name" value="Mrp/NBP35_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000808">
        <property type="entry name" value="Mrp_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044304">
        <property type="entry name" value="NUBPL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033756">
        <property type="entry name" value="YlxH/NBP35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42961">
        <property type="entry name" value="PTHR42961"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10609">
        <property type="entry name" value="ParA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01215">
        <property type="entry name" value="MRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="107"/>
            <end position="114"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="361" mass="38894" checksum="35D582D4541BABF3" modified="2010-01-19" version="1">MNNEKITRFESVSDVCRWLNQFEHPWLHPEWADIPNVVSVSAQGTVSITLPFAAATLIEQLNAWLAQEKSQLNVAVEFEVKSRVAPLAAGEKAPLKGIKNIVVVSSAKGGVGKSTTSVNLALGLQQQGAKVGLLDADIYGPSVPMMLGTVNEKPQSPDGKMMLPVESCGLYTNSVGYLVPAESATIWRGPMASKALAQIINETWWPDLDYLVIDMPPGTGDIQLTLAQQIPVNGAVVVTTPQDLALADAIKGVSMFNKVDVPVLGIIENMSYHICSNCGHHEAIFGTGGAEKMAQSYSVPLLAQLPLHIQIREDIDNGKPTVAAHPESEHAQAYIELAGQVASRLYWEGKPIAEQITIRTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXF2</accession>
    <name>D0YXF2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001631</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40604">
        <property type="protein sequence ID" value="EEZ40604"/>
        <property type="gene ID" value="VDA_001631"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031NT9">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="53" mass="6282" checksum="F702C1A0A295D170" modified="2010-01-19" version="1">MKHKRVSNKQMRQMMSDLGIGDDHQDEEQLLLERRDQAVSEDKQLINLDSENK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXI5</accession>
    <name>D0YXI5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">Thymidylate kinase</fullName>
            <ecNumber evidence="3 6">2.7.4.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5 6">dTMP kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">tmk</name>
        <name evidence="8" type="ORF">VDA_001691</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>ATP + dTMP = ADP + dTDP</text>
            <dbReference type="Rhea" id="RHEA:13517"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58369"/>
            <dbReference type="ChEBI" id="CHEBI:63528"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.9"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the thymidylate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.9" evidence="3 6"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298524.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001691"/>
    <dbReference type="EnsemblBacteria" id="EEZ40662">
        <property type="protein sequence ID" value="EEZ40662"/>
        <property type="gene ID" value="VDA_001691"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0125">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1585072at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004798">
        <property type="term" value="F:thymidylate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006233">
        <property type="term" value="P:dTDP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006235">
        <property type="term" value="P:dTTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00165">
        <property type="entry name" value="Thymidylate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039430">
        <property type="entry name" value="Thymidylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018095">
        <property type="entry name" value="Thymidylate_kin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018094">
        <property type="entry name" value="Thymidylate_kinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02223">
        <property type="entry name" value="Thymidylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00041">
        <property type="entry name" value="DTMP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01331">
        <property type="entry name" value="THYMIDYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thymidylate_kin" evidence="7">
        <location>
            <begin position="8"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="10"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00029962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ40662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="209" mass="23053" checksum="57BA63F8CCA41D72" modified="2010-01-19" version="1">MNGKFIVIEGLEGAGKSTAISQVINVLAEHGIHDPVATREPGGTPLAEQMRALVKEGHPDEPLTDMAELLLLYAARIQLVDNVIKPALAQGRWVVGDRHDMSSQAYQGGGRGFEQQLMMNLRNTVLGDFCPDFTIYMDIDPALGLQRARGRGALDRIEQMNIDFFHRARARFLELSEQDPNTVIIDASQSLEAVTADISSALTQWLEQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXI7</accession>
    <name>D0YXI7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative deoxyribonuclease YcfH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001693</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298526.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001693"/>
    <dbReference type="EnsemblBacteria" id="EEZ40664">
        <property type="protein sequence ID" value="EEZ40664"/>
        <property type="gene ID" value="VDA_001693"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0084">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="915852at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004536">
        <property type="term" value="F:deoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01310">
        <property type="entry name" value="TatD_DNAse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018228">
        <property type="entry name" value="DNase_TatD-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015991">
        <property type="entry name" value="Hydrolase_TatD-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001130">
        <property type="entry name" value="TatD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01026">
        <property type="entry name" value="TatD_DNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005902">
        <property type="entry name" value="DNase_TatD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00010">
        <property type="entry name" value="TIGR00010"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01137">
        <property type="entry name" value="TATD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01090">
        <property type="entry name" value="TATD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01091">
        <property type="entry name" value="TATD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="259" mass="29266" checksum="1547B0FC62F69B7F" modified="2010-01-19" version="1">MLVDSHCHLDKLNYGELHTGIDDVLTKAKERGVEYFLSIGCTLQGFPTMMELIEPYDNVFASCGVHPLDIEEGFDYEQLKAFSSHDRVIAIGETGLDYFYQPELAEKQQEAFRMQVRLAVELNKPLIIHTRMAREDTLRILREEGAQKCGGVIHCFTENLEFAQAAIELGFYISISGIVTFNKSSDLKNVVAQLPLERLLVETDSPFLAPVPFRGKENQPAYVREVAQYVALLKGVSVEEVESVTTDNFFNLFSFATRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXM4</accession>
    <name>D0YXM4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001765</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001765"/>
    <dbReference type="EnsemblBacteria" id="EEZ40733">
        <property type="protein sequence ID" value="EEZ40733"/>
        <property type="gene ID" value="VDA_001765"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="73" mass="8279" checksum="622CEB79F05780B7" modified="2010-01-19" version="1">MDASIDPQWQGNEDWVKFGLGTYLGFPLFYGDQVVGTVCALHDKPYDFYQGDPAAYEQLTKLKQQLEQSMLGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXP7</accession>
    <name>D0YXP7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Succinate-semialdehyde dehydrogenase [NADP+]</fullName>
            <ecNumber evidence="6">1.2.1.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_001750</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.16" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298625.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001750"/>
    <dbReference type="EnsemblBacteria" id="EEZ40718">
        <property type="protein sequence ID" value="EEZ40718"/>
        <property type="gene ID" value="VDA_001750"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1012">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="384611at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009013">
        <property type="term" value="F:succinate-semialdehyde dehydrogenase [NAD(P)+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009450">
        <property type="term" value="P:gamma-aminobutyric acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010102">
        <property type="entry name" value="Succ_semiAld_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01780">
        <property type="entry name" value="SSADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="5">
        <location>
            <begin position="19"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="255"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="482" mass="51872" checksum="ADDD6C0A3FD0C56A" modified="2010-01-19" version="1">MSQLLNLLAQKQTIIAGEWRSANDGRLSDINNPATGEIIGSVPFCGSAETEQAVEMAHSTHLKWKKTLAKERSQILRRWYELVLSNIDELAQILTLEQGKPLAEAKGEIQYAASFIEWYAEEAKRTYGEIVPSHKSDARILVSHQAIGVVGAITPWNFPAAMITRKCAPAFAAGCAVVLKPAPDTPFTALAFAKLAQQAGIPDGLFSVITGDAVAIGGVLTSHKLVKKISFTGSTPVGKLLMQQASNTVKKVSLELGGNAPFIVFDDADLDKAIEGYMIAKYRNAGQTCVCANRLYIQRGIYELFLSKLEAKVEQLKMGNGLDAGVTIGPLINRAAAEKVERHIQDAISKGASLVTGSLQSSDNCFVTPAIIRDLHDDMLVAQEETFGPLASAFVFDSEEEVIARANNTDSGLAAYVYTQSLSRAFTMSEALEYGMVGVNEGLISTEVAPFGGIKESGLGREGARQGIDEYMEVKYTLMGGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-12-02" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXZ3</accession>
    <name>D0YXZ3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein ImpC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002156</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002156"/>
    <dbReference type="EnsemblBacteria" id="EEZ41124">
        <property type="protein sequence ID" value="EEZ41124"/>
        <property type="gene ID" value="VDA_002156"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3517">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010269">
        <property type="entry name" value="T6SS_TssC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044032">
        <property type="entry name" value="TssC1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044031">
        <property type="entry name" value="TssC1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35565">
        <property type="entry name" value="PTHR35565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05943">
        <property type="entry name" value="VipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18945">
        <property type="entry name" value="VipB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03355">
        <property type="entry name" value="VI_chp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VipB" evidence="1">
        <location>
            <begin position="1"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="VipB_2" evidence="2">
        <location>
            <begin position="207"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="321" mass="36675" checksum="0D96F1BB911DD412" modified="2010-01-19" version="1">MKLLQYAGAVGAMAHAPFISGVAPEFFGIDSFEQLPNIKDLKATFESPRYTKWRQLRESDDARYIALTAPRFLLRTPYDPTENPIKTFNYRENVSESHESYLWGNTAFALASRLTDSFAKYRWCPNIIGPQSGGAVEDLPVHLFESMGELQAKIPTEVLVTDRKEFELAEEGFIALTMRKGSDNAAFFSANSIQQPKVFPNTKEGREAEMNFKLGTQLPYMMIINRLAHYVKVLQREQIGSWKERQDLERELNAWIKQFVADQENPPADVRSRRPLRAAQIDVLDVEGDPGWYQVALTVRPHFKYMGANFELSLVGRLDQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY03</accession>
    <name>D0YY03_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_002166</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002166"/>
    <dbReference type="EnsemblBacteria" id="EEZ41134">
        <property type="protein sequence ID" value="EEZ41134"/>
        <property type="gene ID" value="VDA_002166"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="120"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="141"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="202"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="407" mass="45432" checksum="5F33A987BFD5B7CC" modified="2010-01-19" version="1">MLFIHQVFVSSEAFYHKQLDRELTSEASTFSLLVSVGDINKIYRLIEERSRASKTFFYRIQKRSGSKTSINYPVLLTSADYYHEGNKRTEVVVRLSATEKLIIGINPNLLRSYRDTVTPILLSGIAIPVILMLAGATLFSLSILKKLARVNQGMSRVISGEKGVKLPESSNDDEFNLLTKKLNFLIEQVEKNESSLKDLSVGMAHDLRTPIARIKLRLEKVLAANPQPYTNELEACHDDLETLLNMFNGLLEISRLNSGKQDVHKEIAHLDVIAQDAVEFLTPLAEEKQQELIFRVDSSFELSGEPSLLFRAVYNLVENAIKYTPKKGTITVVVDPFGLVVVDTGMGVSSKDKLRIKEPMFRADASRTKQGYGLGLSLVDAVVQSHGGELVFSDNKPGLRARILFSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY20</accession>
    <name>D0YY20_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="13">TonB-dependent heme and hemoglobin receptor HutA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">VDA_002183</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299605.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002183"/>
    <dbReference type="EnsemblBacteria" id="EEZ41151">
        <property type="protein sequence ID" value="EEZ41151"/>
        <property type="gene ID" value="VDA_002183"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4771">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="439303at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015232">
        <property type="term" value="F:heme transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039426">
        <property type="entry name" value="BtuB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011276">
        <property type="entry name" value="TonB_haem/Hb_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010949">
        <property type="entry name" value="TonB_Hb/transfer/lactofer_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010917">
        <property type="entry name" value="TonB_rcpt_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30069">
        <property type="entry name" value="PTHR30069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01785">
        <property type="entry name" value="TonB-hemin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01786">
        <property type="entry name" value="TonB-hemlactrns"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01156">
        <property type="entry name" value="TONB_DEPENDENT_REC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0732">Signal</keyword>
    <keyword evidence="6 9" id="KW-0798">TonB box</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018676" evidence="10">
        <location>
            <begin position="23"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="12">
        <location>
            <begin position="45"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="11">
        <location>
            <begin position="274"/>
            <end position="716"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ41151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="718" mass="80546" checksum="8DDEE33C83CD2883" modified="2010-01-19" version="1">MNIKLSFIASSVLLAVSTPSLANSNNESSIFDEVVVSGTRSEQSVKNIPSTVSKVTAEQMEKNLATDVKQALKYEPGVTVNGRGRFGMQDFTIRGMSGNRVKMLIDGVEQPISYNPGADVMRKNSNTIEVDTLTAIEINKGPSSSLYGSDALGGTVFLRTKNPEDMLDAGDDSHVGVTSGYSSADEQYKLGFEVANRTGDLESMLIYTYRNGHETDTYYKDSNEIGNARKAANPFDIASHNVLAKIFYQINGANRVGFTAEYYTRSADGRILSSDGKTVPMRPPMPPIMYSNNRADDHDHRLRLGLEHEWLAEIAAFDSLEWKLNWTESESKHNSYDKTNYYGNRNRYRDGTDDTIQLDIQMKKELELANNRHEITYGVSGTNNTFDITYTDYNLDKGTSKPGPEEVPKSKSEKRAVFVQDQMFMLDEKLVVTAGLRYDDYQAKPDSDTLKDHKSDAFTGRLGAVYHFTDNFSTYGQFTQGFRAPTIHELYYDKENLAHGYKVISNPNLKPEESDAVELGLRLNGHLGSVATSVFYNNYKNFIKDVTTYDSNNIQITTNENVDKAKIYGAELKTSIWLDEALNAPMGTYANFSVAYTRGEDKKTGRELDTVAPLTAVLGLGYDSPDEMWGGVVDVTMVATKDKWQEEDHFNTPGYTVVDMTTYYRPSKDLTVRAGLFNAFDKKYWQYQNIDGITVGKENINRKTEPGRNWGVNVKYDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY26</accession>
    <name>D0YY26_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0263 protein VDA_002189</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002189</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0263 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299616.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002189"/>
    <dbReference type="EnsemblBacteria" id="EEZ41157">
        <property type="protein sequence ID" value="EEZ41157"/>
        <property type="gene ID" value="VDA_002189"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3099">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1872054at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00680">
        <property type="entry name" value="UPF0263"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007376">
        <property type="entry name" value="dsDNA_mimic_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036763">
        <property type="entry name" value="Put_dsDNA_mimic_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04269">
        <property type="entry name" value="DUF440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004916">
        <property type="entry name" value="UCP004916"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102816">
        <property type="entry name" value="SSF102816"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="108" mass="12669" checksum="D2339A54421DC759" modified="2010-01-19" version="1">MDNSNLISYDDVIDAAYDIFLEMAQDNLEPADILLFTMQFDDRGAAELVETKDDWAEHVGFDVDKERYAEVRIGLVNEETDELDDVFARMLICREEDNKFCHILWKRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY58</accession>
    <name>D0YY58_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Ferric siderophore transport system binding protein TonB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">VDA_002221</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
            <orientation evidence="1">Periplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TonB family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299677.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002221"/>
    <dbReference type="EnsemblBacteria" id="EEZ41189">
        <property type="protein sequence ID" value="EEZ41189"/>
        <property type="gene ID" value="VDA_002221"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0810">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1704906at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006260">
        <property type="entry name" value="TonB/TolA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037682">
        <property type="entry name" value="TonB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03544">
        <property type="entry name" value="TonB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01352">
        <property type="entry name" value="tonB_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_C" evidence="11">
        <location>
            <begin position="175"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="87"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="87"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="103"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="124"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ41189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="252" mass="27268" checksum="2B895E6933B3C128" modified="2010-01-19" version="1">MDTTRYVIAGAVSVIIHGLILSAVPSQNAIAMPIGNQIAPVSLNLVTAPIAPPPPAQDVAKAEVKPQKSVKKTQQIEQKTAVKKLVKKTTPTKKAAKKVANKTTKTKKAEQKPVVKNRDSKPVKSATKPQPQSKLKNETSQVANTANNKKALLSSGTQSPELVSRPTFATRPGPVSYPRLAKRRGIQGQVMVEIWIDPKGKQIKQKVISSSGTEILDQAALTAIKKWKFSSHIVDGQAIAHRVHIPVRFQLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY88</accession>
    <name>D0YY88_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ribosomal RNA large subunit methyltransferase I</fullName>
            <ecNumber evidence="5">2.1.1.191</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">23S rRNA m5C1962 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">rRNA (cytosine-C(5)-)-methyltransferase RlmI</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rlmI</name>
        <name evidence="7" type="ORF">VDA_002251</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Specifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>cytidine(1962) in 23S rRNA + S-adenosyl-L-methionine = 5-methylcytidine(1962) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42912"/>
            <dbReference type="Rhea" id="RHEA-COMP:10382"/>
            <dbReference type="Rhea" id="RHEA-COMP:10386"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74483"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.191"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the methyltransferase superfamily. RlmI family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.191" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299736.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002251"/>
    <dbReference type="EnsemblBacteria" id="EEZ41219">
        <property type="protein sequence ID" value="EEZ41219"/>
        <property type="gene ID" value="VDA_002251"/>
    </dbReference>
    <dbReference type="GeneID" id="57341591"/>
    <dbReference type="eggNOG" id="COG1092">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="468283at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016434">
        <property type="term" value="F:rRNA (cytosine) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01857">
        <property type="entry name" value="23SrRNA_methyltr_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002478">
        <property type="entry name" value="PUA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036974">
        <property type="entry name" value="PUA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041532">
        <property type="entry name" value="RlmI_PUA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023542">
        <property type="entry name" value="rRNA_lsu_MeTfrase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019614">
        <property type="entry name" value="SAM-dep_methyl-trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10672">
        <property type="entry name" value="Methyltrans_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17785">
        <property type="entry name" value="PUA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00359">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 5" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="4 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PUA" evidence="6">
        <location>
            <begin position="3"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="396" mass="44098" checksum="982F5F8BC1F62E7F" modified="2010-01-19" version="1">MTASIYLVKGREKSLLRRHPWVFSRGIARVEGDPQLGDTVEIFDNKGQWLARGAYSPQSQIRVRVWTFNKNEKIDVEFFVNRLQTAQALRDVLAARDGLTGYRLIAAESDGLPGITIDKYQDYLVCQLLSAGAEAQKEALVEALQICYPLCNVYERSDVAVRKKEGLAQRTGVLVGNEPPKFVTIEENGVKINVDIKGGHKTGFYLDQRDSREAAVKYVNGKRVLNCFCYTGGFGLYALKGGASQVVNVDVSQPALDTAKMNAEMNGYPLENAEFLNADVFKLLREYRDRGEQFDVVIMDPPKFAESKSQLVGACRGYKDINMLAMQITKPGGMLLTYSCSGLMDGNLFQKIIADAALDAKRDVQFIERFAQAADHPLDSAYPEGFYLKGFACYVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYB8</accession>
    <name>D0YYB8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Prophage Lp2 protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002281</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299780.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41249">
        <property type="protein sequence ID" value="EEZ41249"/>
        <property type="gene ID" value="VDA_002281"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4748">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="849234at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029464">
        <property type="entry name" value="HSDR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017035">
        <property type="entry name" value="UCP035009_HsdR_All3000-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13588">
        <property type="entry name" value="HSDR_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF035009">
        <property type="entry name" value="UCP035009_HSDR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HSDR_N_2" evidence="1">
        <location>
            <begin position="46"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="358" mass="41011" checksum="293F18D312C26AA6" modified="2010-01-19" version="1">MEFVDRLESLSKKVAQVSNNLATEEATKNALVMPFLHSVLGYDVFDPNEVVPEFTADTGTKKGEKVDYALMKDGVVQILIECKKFDEQLSTKHANQLFRYFSVTNARIAILTNGCQYQFYTDLDAPNKMDEKPFLILDLSDLDEHIVPEIKKLTKSSFDVDSVVDAAGELKYLNQIKKVLSEQFQNPDEDFVKYFTSKVYEGVQTAKVKSQFLDITTKALKQFLNDSINARLKSAIGNDVKDSIQDEIITKSDENKEINDRPKVDTTDDEIEGFNIVKAIFRQKIGLNRVYSRDTQSYFGVLLDDNNRKPLCRLHFNAKQKYIGIFDGNRNETRYPIDSLDDIFSYTEQLQNTISLYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYD6</accession>
    <name>D0YYD6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Adenosylmethionine-8-amino-7-oxononanoate aminotransferase</fullName>
            <ecNumber evidence="4">2.6.1.62</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">7,8-diamino-pelargonic acid aminotransferase</fullName>
            <shortName evidence="4">DAPA AT</shortName>
            <shortName evidence="4">DAPA aminotransferase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">7,8-diaminononanoate synthase</fullName>
            <shortName evidence="4">DANS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Diaminopelargonic acid synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">bioA</name>
        <name evidence="6" type="ORF">VDA_002299</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(8S)-8-amino-7-oxononanoate + S-adenosyl-L-methionine = (7R,8S)-7,8-diammoniononanoate + S-adenosyl-4-methylsulfanyl-2-oxobutanoate</text>
            <dbReference type="Rhea" id="RHEA:16861"/>
            <dbReference type="ChEBI" id="CHEBI:16490"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:149468"/>
            <dbReference type="ChEBI" id="CHEBI:149469"/>
            <dbReference type="EC" id="2.6.1.62"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; biotin biosynthesis; 7,8-diaminononanoate from 8-amino-7-oxononanoate (SAM route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.62" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299818.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002299"/>
    <dbReference type="EnsemblBacteria" id="EEZ41267">
        <property type="protein sequence ID" value="EEZ41267"/>
        <property type="gene ID" value="VDA_002299"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0161">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="478143at2"/>
    <dbReference type="UniPathway" id="UPA00078">
        <property type="reaction ID" value="UER00160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004015">
        <property type="term" value="F:adenosylmethionine-8-amino-7-oxononanoate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009102">
        <property type="term" value="P:biotin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00834">
        <property type="entry name" value="BioA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005815">
        <property type="entry name" value="BioA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00508">
        <property type="entry name" value="bioA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4" id="KW-0093">Biotin biosynthesis</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4 5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="4">
        <location>
            <begin position="111"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="4">
        <location>
            <begin position="307"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="244"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="273"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="306"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="390"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM" evidence="4">
        <location>
            <position position="16"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="4">
        <location>
            <position position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="425" mass="47186" checksum="3BBEC179856E78A8" modified="2010-01-19" version="1">MSIDLQFDKDHIWHPYTSTINPLPCYPVSKADGVIITLEDGRELIDGMSSWWAAVHGYNHPVLNEAAKSQLDNMSHIMFGGLTHRPAVDVCKKLVQLTPPSLQHVFLADSGSVAVEVALKMALQYWHSKGESRAKFLTLRHGYHGDTFAAMSVTDPDNSMHALYKGFLPEHIFAQSPSCGFHDDWDESDIADFEQQLSTHHQQLAAVILEPIVQGAGGMRLYHPMYLKRVRELCDRYHVLLIADEIATGFGRTGKLFACEHAQIEPDIMSVGKALTGGYMTLAATITTKHVADTVCSGEAGCFMHGPTFMGNPLACAVASANLDLIAQNQWQHQVSQIEQQLSQQLPPIASLSNVKEVRWLGAIGVVELHHPVEMVSIQQAFVDYGIWVRPFGKLVYIMPPFIIQPEQLSKLTQGLYEVLKPLQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYF3</accession>
    <name>D0YYF3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002316</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299848.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002316"/>
    <dbReference type="EnsemblBacteria" id="EEZ41284">
        <property type="protein sequence ID" value="EEZ41284"/>
        <property type="gene ID" value="VDA_002316"/>
    </dbReference>
    <dbReference type="GeneID" id="57341499"/>
    <dbReference type="eggNOG" id="COG0735">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1947431at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="134" mass="14410" checksum="A1E60F5C7B081B39" modified="2010-01-19" version="1">MRISHKRKVQLKLQKRIQATVVVADTVSVKEAPKADVKKAAPAAKTVEKKDSAKVEVAKSEVVTSVNLTPKQQQVLDIVKANTDGINPKGIGLEAGQEDSKAASWATGALKKLVEENLVERIQLSGNKVLYKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYJ1</accession>
    <name>D0YYJ1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative sulfate permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_002354</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Membrane</location>
            <topology evidence="1 5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41322">
        <property type="protein sequence ID" value="EEZ41322"/>
        <property type="gene ID" value="VDA_002354"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0659">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008271">
        <property type="term" value="F:secondary active sulfate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001902">
        <property type="entry name" value="SLC26A/SulP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11814">
        <property type="entry name" value="PTHR11814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="57"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="80"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="106"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="139"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="180"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="209"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="259"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="332"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="355"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="387"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="6">
        <location>
            <begin position="443"/>
            <end position="559"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="585" mass="63206" checksum="4212DD88CAED3B09" modified="2010-01-19" version="1">MSHSFSLKIHDLIPGLKSLQKYDRSWFPDDLRAALSVVAVALPVAIAYAQLAGVNEIAGLYACVLPMIAYAFFGTSRQLIVGPDAATCAVIAAVVTPLAAGDSVKHLQLVVTMTIMTGLWCLIASRFKLGVLADFLSRPILMGLLNGVAITIIVGQFAKITGVKFEEKHLLERIYAVPDYLASIHWPTVGTAAFTLLVFLLFKRFKPTWPAAMLAIAIAAFAVFILHLDQYGIAILGDVKGGLPTFSLPVFDLGLTRELVMPALNLAMVSFVSMMLTARSFAARNGYEIDADKEFRALGIANLASALSQGFAISGADSRTAVNDASGGKSQLVSIIAAIVIGVIALFVYEPLRYIPHAALGVILVISSISLLDFIGMWALKTRDRDAFLLATITFVAVLIIGVIPGITLAVLLGLFQFIRVVMRPSDQTMGLDDKGVLRSLDDSDKAAAIPGVFIYRFNSPLTYFNAAYFKRRLLQQISQQETPPACVIIDAVASFTHMDVSVMAVLDDIHGILKRKGVRLILAGRKRQLQKWCELVGMNMGDGGITIRSDMYLAIKMSGCYRQAYADGLVAEVKKNEVTAAIAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYJ7</accession>
    <name>D0YYJ7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002360</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299953.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002360"/>
    <dbReference type="EnsemblBacteria" id="EEZ41328">
        <property type="protein sequence ID" value="EEZ41328"/>
        <property type="gene ID" value="VDA_002360"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1988">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1742864at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007404">
        <property type="entry name" value="YdjM-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04307">
        <property type="entry name" value="YdjM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="183"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="255" mass="28135" checksum="8B964B85F8A20D30" modified="2010-01-19" version="1">MANFTTHFTVAAVVSGVAAAALLSAEHVMPVTAIWLAFLGTMGGLLPDIDSDHSTSMKWLFTLLASFSCFILLCHIYSHVTMLELLFYIVGLFIIVQVIIKAWVQRITIHRGCCHSIAFVTLLALCVTHLASLLGYKNTFSWLSGGFVLLGGLVHLILDEIYSVDLANKRIKSSFGSALKPFSLSNPFISLAQVTAIVLLLYSAPPAHSTIRLLSHWQHFHFSPSWLNVDQAQYWLKNVLNSTADKIKTVHIPSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYR8</accession>
    <name>D0YYR8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 10">Quinolinate synthase</fullName>
            <ecNumber evidence="2 10">2.5.1.72</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">nadA</name>
        <name evidence="11" type="ORF">VDA_002431</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>dihydroxyacetone phosphate + iminosuccinate = H(+) + 2 H2O + phosphate + quinolinate</text>
            <dbReference type="Rhea" id="RHEA:25888"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29959"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:77875"/>
            <dbReference type="EC" id="2.5.1.72"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="10">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Cofactor biosynthesis; NAD(+) biosynthesis; quinolinate from iminoaspartate: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the quinolinate synthase family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.72" evidence="2 10"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300079.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002431"/>
    <dbReference type="EnsemblBacteria" id="EEZ41399">
        <property type="protein sequence ID" value="EEZ41399"/>
        <property type="gene ID" value="VDA_002431"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0379">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="613347at2"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00327"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008987">
        <property type="term" value="F:quinolinate synthetase A activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10800">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00567">
        <property type="entry name" value="NadA_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003473">
        <property type="entry name" value="NadA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036094">
        <property type="entry name" value="NadA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023513">
        <property type="entry name" value="Quinolinate_synth_A_type1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30573">
        <property type="entry name" value="PTHR30573"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02445">
        <property type="entry name" value="NadA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142754">
        <property type="entry name" value="SSF142754"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00550">
        <property type="entry name" value="nadA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 10" id="KW-0408">Iron</keyword>
    <keyword evidence="9 10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="7 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 10" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Iminoaspartate binding" evidence="10">
        <location>
            <begin position="139"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Iminoaspartate binding" evidence="10">
        <location>
            <begin position="226"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>iminosuccinate</name>
            <dbReference type="ChEBI" id="CHEBI:77875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>iminosuccinate</name>
            <dbReference type="ChEBI" id="CHEBI:77875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>iminosuccinate</name>
            <dbReference type="ChEBI" id="CHEBI:77875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="200"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="243"/>
        </location>
        <ligand>
            <name>iminosuccinate</name>
            <dbReference type="ChEBI" id="CHEBI:77875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="297"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ41399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="347" mass="37920" checksum="F618A7638A99E9F4" modified="2010-01-19" version="1">MTKQFNPAETIYPFPPKPTPLTADERATYKESIQRLLVEKDAVMVAHYYTDPEIQALAEETGGFVGDSLEMARFGNQHPAKTLLVCGVRFMGESAKILTPEKQILMPTLEAECSLDLGCPAEAFTQFCDEHPEHTVVVYANTSAAVKARADWVVTSSIALEIVEHLEAEGKPIIWGPDRHLGSYIQKQTDADMLLWQGECVVHDEFSAKALRDMKAVYPDAAILVHPESPASVVALADAVGSTSQLIKAAKSLPNQQLIVATDKGIFYKMQQMVPEKELIEAPTAGAGATCRSCAHCPWMAMNGLKAIETALIDGGAEHEIFVDEAIRVQSLVPLNRMLDFAANLQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-06-02" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYS2</accession>
    <name>D0YYS2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TolA protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002435</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002435"/>
    <dbReference type="EnsemblBacteria" id="EEZ41403">
        <property type="protein sequence ID" value="EEZ41403"/>
        <property type="gene ID" value="VDA_002435"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3064">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019534">
        <property type="term" value="F:toxin transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043213">
        <property type="term" value="P:bacteriocin transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014161">
        <property type="entry name" value="Tol-Pal_TolA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06519">
        <property type="entry name" value="TolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02794">
        <property type="entry name" value="tolA_full"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="331" mass="36875" checksum="E032DA16D16F3AF8" modified="2010-01-19" version="1">MTESKPAGNAIQAVVVDPALVHQQAQRIRDQRQAAQKAEQDRLKRLEQQADALEKQRKAEAERVRKLKEDKLAAEKATREAEAERKAKQEAAEKAEQLRQQKLVEQRKAEAAAKKADAERKVKEAAAAKAEAERKAKQEAAEKAEQLRQQKVAEQRKAEEAAKKAEADRKAKEAAKKKAEEAAKLAEQKRIEAEKQRKESERKAAEAKAKQQQQEAALDNIFDGLEAETQQRGGAKGQFIADETQRYGAIYKQMIQQNLLTDQSFIGKQCVLSMRLSANGLLLNVDQVSGDNTLCRAAKAAVVKISQFPMPEDPAVIEKLRNIKLTVSPQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYU4</accession>
    <name>D0YYU4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">UPF0056 membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_002457</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the UPF0056 (MarC) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300130.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002457"/>
    <dbReference type="EnsemblBacteria" id="EEZ41425">
        <property type="protein sequence ID" value="EEZ41425"/>
        <property type="gene ID" value="VDA_002457"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2095">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1323133at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002771">
        <property type="entry name" value="Multi_antbiot-R_MarC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33508">
        <property type="entry name" value="PTHR33508"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01914">
        <property type="entry name" value="MarC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00427">
        <property type="entry name" value="TIGR00427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="44"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="79"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="118"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="145"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="187"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ41425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="212" mass="22509" checksum="19B959AF1008A3BD" modified="2010-01-19" version="1">MPSLEFAIFLQFFVGLIAAVNPIGIMPVYVSLTGHMTPEERNRTALTANVAVAIILIVSLLAGQWLLDMFSISLDSFRVAGGLLLLTIAFSMMSGKIGEGKQNKQEISESVSREQIGVVPLAMPLLAGPGAISSTIVYGSRYPGLTSILGIAATIITFAFCCWLLFRAAPLIVRVLGQTGINVITRIMGLILAALGIEFIANGLRALFPGLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYU6</accession>
    <name>D0YYU6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycerophosphoryl diester phosphodiesterase</fullName>
            <ecNumber evidence="3">3.1.4.46</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002459</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.4.46" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300134.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002459"/>
    <dbReference type="EnsemblBacteria" id="EEZ41427">
        <property type="protein sequence ID" value="EEZ41427"/>
        <property type="gene ID" value="VDA_002459"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0584">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1542724at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008889">
        <property type="term" value="F:glycerophosphodiester phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030395">
        <property type="entry name" value="GP_PDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03009">
        <property type="entry name" value="GDPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="SSF51695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51704">
        <property type="entry name" value="GP_PDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019886" evidence="1">
        <location>
            <begin position="22"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="domain" description="GP-PDE" evidence="2">
        <location>
            <begin position="28"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="361" mass="41330" checksum="6565E7FE86CD67F2" modified="2010-01-19" version="1">MTKLGLTLALTAAMLAPSAFAQSDLSDKIVVAHRGASGYLPEHTLPAKALAYAMHPDYIEQDVVMTKDNQLVVLHDHYLDRVTNVAEVFPDRARKDGRYYAIDFTLPEIKQLTVTEGFNIENGKQVQGFPDRFPMWKSHFTVPTFQEEIEMIQGLNKTLGYDIGLYPEIKAPWFHRHEGKDISKAVLKVLKQYGYTNKDSKVYLQTFDFNELKRINDELMPELDMDLNLVQLMAYTDWNETMVYDKDGKAQPYSYDWMFKPDGMKKLSKYADGIGPWKPMVVSDKSTKDNIQLTGLVKAAHENGMVVHPYTFRADKGRIPAYTDDFNGMLEVFYKTANVDGVFTDFPDKAVDYLRQQNSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYW6</accession>
    <name>D0YYW6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Septum site-determining protein MinD</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Cell division inhibitor MinD</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">VDA_002479</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Interacts with MinC and FtsZ.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ParA family. MinD subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300171.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002479"/>
    <dbReference type="EnsemblBacteria" id="EEZ41447">
        <property type="protein sequence ID" value="EEZ41447"/>
        <property type="gene ID" value="VDA_002479"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2894">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1631847at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025669">
        <property type="entry name" value="AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010223">
        <property type="entry name" value="MinD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025501">
        <property type="entry name" value="MinD_FleN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13614">
        <property type="entry name" value="AAA_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003092">
        <property type="entry name" value="MinD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01968">
        <property type="entry name" value="minD_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_31" evidence="10">
        <location>
            <begin position="3"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ41447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="270" mass="29469" checksum="90FA05FE5F5B8EA3" modified="2010-01-19" version="1">MARIIVVTSGKGGVGKTTSSAAIASGLALRGKKTAVIDFDIGLRNLDLIMGCERRVVYDFVNVINGEANLNQALIKDKRTDNLFVLPASQTRDKDALSKEGVERVLKDLGEMGFDFVICDSPAGIETGALMALYFADEAIVTTNPEVSSVRDSDRILGILDSKSRRAEQGQEPVKQHLLLTRYNPTRVNQGDMLSVQDVEEILHIPLLGVIPESQAVLNASNKGEPVIFDKDADASIAYQDTVARLLGEECPFRFLEEEKKGFLKRLFGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ17</accession>
    <name>D0YZ17_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Hypothetical dksA-type zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_002530</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002530"/>
    <dbReference type="EnsemblBacteria" id="EEZ41498">
        <property type="protein sequence ID" value="EEZ41498"/>
        <property type="gene ID" value="VDA_002530"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1734">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000962">
        <property type="entry name" value="Znf_DskA_TraR"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51128">
        <property type="entry name" value="ZF_DKSA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DksA C4-type" evidence="5">
        <location>
            <begin position="6"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="dksA C4-type" evidence="4">
        <location>
            <begin position="49"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="83" mass="9478" checksum="A23710823E812FBA" modified="2010-01-19" version="1">MEELNKLDLYDLLALAKAAYIPNLYKLATRLEVVDAAVCSIRFGLYGLCADCEEEIDLADLEVDPAQPRCRHCREHSRYHHDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ45</accession>
    <name>D0YZ45_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cysteine synthase B</fullName>
            <ecNumber evidence="4">2.5.1.47</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_002558</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="2.5.1.47" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300322.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002558"/>
    <dbReference type="EnsemblBacteria" id="EEZ41526">
        <property type="protein sequence ID" value="EEZ41526"/>
        <property type="gene ID" value="VDA_002558"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0031">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1677960at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004124">
        <property type="term" value="F:cysteine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PALP" evidence="3">
        <location>
            <begin position="31"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="362" mass="40667" checksum="E05938C17257D309" modified="2010-01-19" version="1">MNAKLKSCNKTEWINNAIRKIDADYQRSADTHLIKLDIPSLDGIDIYLKDESTHPTGSLKHRLARSLFLYALCNGWITEGTPIIESSSGSTAVSEAYFARLLGLPFIAVVPRKTARKKIEQIEFYGGKAHFVDCPSEIYAESRRLAQELNGHYMDQFTYAERATDWRGNNNIANSIFEQMKFEQHPIPTWIVMSPGTGGTSATIGRYIRYQMQPTRLCVVDPENSVFAPYYQSRDCSLTSAVGSRIEGIGRPRVEPSFIPDVVDEMRTIPDAASVATVHWLEKLLGRKAGASTGTNLYGVLQLACEMKQRGETGSIVTLLCDSGERYLDTYYDEQWVRDNIGDLSPYLAQLEQLEQSGDWSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ67</accession>
    <name>D0YZ67_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Positive regulator of CheA protein activity (CheW)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002580</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002580"/>
    <dbReference type="EnsemblBacteria" id="EEZ41548">
        <property type="protein sequence ID" value="EEZ41548"/>
        <property type="gene ID" value="VDA_002580"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0835">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039315">
        <property type="entry name" value="CheW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036061">
        <property type="entry name" value="CheW-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002545">
        <property type="entry name" value="CheW-lke_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22617">
        <property type="entry name" value="PTHR22617"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01584">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00260">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50341">
        <property type="entry name" value="SSF50341"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50851">
        <property type="entry name" value="CHEW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CheW-like" evidence="1">
        <location>
            <begin position="1"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="129" mass="14238" checksum="BB21FAD69C2914BD" modified="2010-01-19" version="1">MQVREVLRYSEIAPVPGAPDYVLGIINLRGNVVTVIDTRSRFGLMPGDISDNTRIVIIEAEKQVIGILVDSVAEVVYLRSSEIDSTPSVGTEESAKFIQGVCNRDGNLLILVDLNKLLSDDEWDEMAYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ71</accession>
    <name>D0YZ71_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphorelay protein LuxU</fullName>
            <ecNumber evidence="3">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">VDA_002584</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300396.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002584"/>
    <dbReference type="EnsemblBacteria" id="EEZ41552">
        <property type="protein sequence ID" value="EEZ41552"/>
        <property type="gene ID" value="VDA_002584"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0643">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2198">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="305000at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00088">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.560">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004105">
        <property type="entry name" value="CheA-like_dim"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037006">
        <property type="entry name" value="CheA-like_homodim_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036061">
        <property type="entry name" value="CheW-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002545">
        <property type="entry name" value="CheW-lke_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036641">
        <property type="entry name" value="HPT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008207">
        <property type="entry name" value="Sig_transdc_His_kin_Hpt_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01584">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02895">
        <property type="entry name" value="H-kinase_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01627">
        <property type="entry name" value="Hpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00260">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01231">
        <property type="entry name" value="H-kinase_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00073">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47226">
        <property type="entry name" value="SSF47226"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50341">
        <property type="entry name" value="SSF50341"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50851">
        <property type="entry name" value="CHEW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50894">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="domain" description="HPt" evidence="10">
        <location>
            <begin position="2"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="8">
        <location>
            <begin position="416"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="domain" description="CheW-like" evidence="9">
        <location>
            <begin position="629"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="191"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="269"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="326"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="198"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="269"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="332"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphohistidine" evidence="6">
        <location>
            <position position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ41552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="767" mass="83076" checksum="1BBE7EF59E7D95AF" modified="2010-01-19" version="1">MSFDLDEDILQDFLIEAGEILELLSEQLVELERSPENSELLNAIFRGFHTVKGGAGFLSLTELVDVCHGAENVFDLLRTGKRHVTSELMDVILQALDTINVMFALVQDREPLEQADPSLLAALHRFSQPGDASVAEPIVVTPVVEPEPEIVVVDVPASASSHQEDQPVTSGSSVDDITQDEFERLLDELHGVGKGPSVNEGSSATQSSAPVSNSASTSTQPSDVVRLHIESDSNDITDDEFERLLDELHGSGKGPSSHEDNVAGTESSIVADSANEQTAAEVTSGDEELMSDDEFERLLDQLHGIGKGPSAQELEAATCSVAEMNDQKDEPAPVSQPVSSSERSESQPTPVVAPIRTAEPVAVRETAVKEKAISKPTAETTVRVDTSTLDTIMNMVGELVLVRNRLVSLGLNSNDEEMSKAVANLDVVTADLQGAVMKTRMQPIKKVFGRFPRVVRDLARHLKKDIVLEMQGEETDLDKNLVEALADPLVHLVRNSVDHGIEMPEVRERIGKPRTGTVLLSASQEGDHILLTIEDDGNGMDANKLRAIAVERGIMDSDAASRLTDNEAYNLIFAPGFSTKKEISDISGRGVGMDVVKTAISQLNGSIHIDSAMGKGTRIEIKVPLTLAILPTLMVGVADQPFALPLASVNEIFHLDLRKTNIVDGQLTTIVRDKAVPLFYLQDWLAPRYYTEHKDRDHGHVVIVQIGHQRIGFVVDTLVGQEEVVIKPLDELLQGTPGMAGATITSDGHIALILDVPNLLKHYAGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ76</accession>
    <name>D0YZ76_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Flagellar biosynthesis protein FlhF</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Flagella-associated GTP-binding protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">VDA_002589</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GTP-binding SRP family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300410.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002589"/>
    <dbReference type="EnsemblBacteria" id="EEZ41557">
        <property type="protein sequence ID" value="EEZ41557"/>
        <property type="gene ID" value="VDA_002589"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1419">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1162441at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044781">
        <property type="term" value="P:bacterial-type flagellum organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020006">
        <property type="entry name" value="FlhF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000897">
        <property type="entry name" value="SRP54_GTPase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43134:SF3">
        <property type="entry name" value="PTHR43134:SF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00448">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00962">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03499">
        <property type="entry name" value="FlhF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1005">Bacterial flagellum biogenesis</keyword>
    <keyword evidence="7" id="KW-1006">Bacterial flagellum protein export</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="13" id="KW-0966">Cell projection</keyword>
    <keyword evidence="13" id="KW-0969">Cilium</keyword>
    <keyword evidence="13" id="KW-0282">Flagellum</keyword>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AAA" evidence="11">
        <location>
            <begin position="307"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="domain" description="SRP54" evidence="12">
        <location>
            <begin position="308"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="119"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="170"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="123"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ41557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="528" mass="59529" checksum="508DD0E979C26F35" modified="2010-01-19" version="1">MKIKRFFAKDMRTALNEVKEELGSDAVIMSNKKVTGGVEIVAAVDPDSHPEPMKSSAMQSARDELAYGFGQAKRKLADDHVQLQQSAPSSRFANVLQNYAESQPNGDERQEDSLTALLQRQSKHRQQESEHSYHDEPREFQRHSLSSRHDASAQSQGYDFRAQKHSLDIGDYQRPSSSQYERELHVGNRAKPNYSQRPAKPRLDPSRYEAKSSHQFDDIETMRSELASIRYLLEHQLSGLMWQEVERREPMRAMMVKRLEKMGLSDELADQLASYIPEELPPHQAWPALLDLLSDQIQTIKENVLESGGVVALLGPTGVGKTTTIAKLAARAAMEFGPEQIALVTTDTFRIGAHEQLATYGRIIGCPVRVAKDAEELADILHQLRHRRLVLLDTAGMGQRDIRLSEQLDTLMQNSGAHIRSLLVMPATAQRRVMQETIEHFRRIPLSGCVLTKLDESLSLGEVIAVTIQNALPIAYLADGQRVPEDIKVATGKFLVARANELLEQELNQRPHFWSSDRLEQKAADFYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ80</accession>
    <name>D0YZ80_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 13">Flagellar biosynthetic protein FliP</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">fliP</name>
        <name evidence="15" type="ORF">VDA_002593</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 13">Plays a role in the flagellum-specific transport system.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cell membrane</location>
            <topology evidence="13">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="13">Bacterial flagellum basal body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the FliP/MopC/SpaP family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002593"/>
    <dbReference type="EnsemblBacteria" id="EEZ41561">
        <property type="protein sequence ID" value="EEZ41561"/>
        <property type="gene ID" value="VDA_002593"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1338">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044781">
        <property type="term" value="P:bacterial-type flagellum organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005837">
        <property type="entry name" value="FliP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005838">
        <property type="entry name" value="T3SS_IM_P"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30587">
        <property type="entry name" value="PTHR30587"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30587:SF0">
        <property type="entry name" value="PTHR30587:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00813">
        <property type="entry name" value="FliP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00951">
        <property type="entry name" value="FLGBIOSNFLIP"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01302">
        <property type="entry name" value="TYPE3IMPPROT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01103">
        <property type="entry name" value="fliP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01060">
        <property type="entry name" value="FLIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01061">
        <property type="entry name" value="FLIP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="8 13" id="KW-1005">Bacterial flagellum biogenesis</keyword>
    <keyword evidence="12 13" id="KW-1006">Bacterial flagellum protein export</keyword>
    <keyword evidence="6 13" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="15" id="KW-0966">Cell projection</keyword>
    <keyword evidence="15" id="KW-0969">Cilium</keyword>
    <keyword evidence="15" id="KW-0282">Flagellum</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0732">Signal</keyword>
    <keyword evidence="7 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5 13" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018752" description="Flagellar biosynthetic protein FliP" evidence="14">
        <location>
            <begin position="25"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="72"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="214"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="250"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU362069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEZ41561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="272" mass="29490" checksum="DB23706EB48F9032" modified="2010-01-19" version="1">MISRNIVIVLMFALLGFCSFNALANTSSATAVDSLSQSVPFLSTQKGSTGIPAVSVTVNPDGSEDYSVTLQILALMTALGFLPAIVILMTSFTRIVVVMSILRQALGLQQTPSNQVIIGIALFLTFFVMSPVLDRINAQAVQPYINEQITAPQALEKAKVPMREFMLKQTRVKDLETFVNISGAKVSDPQQVPMTVLIPAFITSELKTAFQIGFMLFLPFLVIDLVVASVLMAMGMMMLSPMIVSLPFKLMLFVLVDGWNLILSTLAGSFAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZC5</accession>
    <name>D0YZC5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted iron-dependent peroxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002638</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300566.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002638"/>
    <dbReference type="EnsemblBacteria" id="EEZ41606">
        <property type="protein sequence ID" value="EEZ41606"/>
        <property type="gene ID" value="VDA_002638"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2837">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="837319at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006314">
        <property type="entry name" value="Dyp_peroxidase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04261">
        <property type="entry name" value="Dyp_perox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01413">
        <property type="entry name" value="Dyp_perox_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51404">
        <property type="entry name" value="DYP_PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 3" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="298" mass="33403" checksum="17ECB58C88CF6900" modified="2010-01-19" version="1">MAISQPAIVPDRGCFALYIVMNVTGDRAKVLSQCQAIHPLLAQLNQEQQDANLHASVAFGKTFWQSLEQNCPPELTEFRQFGQGEVTAPATGGDILLHIHSNRHDLNFYACRKFLELIADDIEVLDETYGFQYLDHRDMTDFIDGTENPQTQEDRQNVAIIPAGEFAGGSYVMVQRFVHNLPAWHRLSVKAQEKVIGRTKPDSVELDDVPAASHVGRVDIKEEGKGLKILRHSLPFGTASGDHGLLFIAYCQRQYHFDAMLENMYGERDGKTDQMLRFSQAVTGAYFFAPSVEMLNAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZI5</accession>
    <name>D0YZI5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Outer membrane protein assembly factor BamB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">bamB</name>
        <name evidence="6" type="ORF">VDA_002698</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the Bam complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the BamB family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300731.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002698"/>
    <dbReference type="EnsemblBacteria" id="EEZ41666">
        <property type="protein sequence ID" value="EEZ41666"/>
        <property type="gene ID" value="VDA_002698"/>
    </dbReference>
    <dbReference type="GeneID" id="57341031"/>
    <dbReference type="eggNOG" id="COG1520">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043165">
        <property type="term" value="P:Gram-negative-bacterium-type cell outer membrane assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051205">
        <property type="term" value="P:protein insertion into membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00923">
        <property type="entry name" value="OM_assembly_BamB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017687">
        <property type="entry name" value="BamB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025666">
        <property type="entry name" value="PQQ-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018391">
        <property type="entry name" value="PQQ_beta_propeller_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002372">
        <property type="entry name" value="PQQ_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13360">
        <property type="entry name" value="PQQ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13570">
        <property type="entry name" value="PQQ_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00564">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03300">
        <property type="entry name" value="assembly_YfgL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5009009107" description="Outer membrane protein assembly factor BamB" evidence="4">
        <location>
            <begin position="23"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="PQQ_3" evidence="5">
        <location>
            <begin position="43"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13570"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="387" mass="41236" checksum="98C00CB9852E04FD" modified="2010-01-19" version="1" precursor="true">MQKVFKRALTVALAIGVLAGCASEEDSIHMAPLPVVKNTFTPETLWSDSVGDGVAGYFSRLTPAIGDGKIFVADRDGLVEALDPSNGKVLWKQDFEGDTSAKLSGGIVYSSGVIYIGSENADVLAINAENGDEIWRAKVQGEVLSKPLVDEGLVVVNTSNGFLQALDVSTGESKWQISSEVPTLTLRGDSSPVAISGGVFWGQANGRLAGALMHNGQLLWQQAIAAPKGATEIDRLVDVDATPVIAGDRLYAIGYNGSLVSIELRTGQIAWKRNYSSATNFIVDANTLYLVTEKDHIVAVDARSGTEIWQNKDLEYRQLTAPAAIDGYLVVGDAEGYLHWLDQSTGDFVSQESIGGGGMSVPPVALDDDAFIVSTRDGKIKKMQISQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z014</accession>
    <name>D0Z014_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8 10">Uracil-DNA glycosylase</fullName>
            <shortName evidence="8">UDG</shortName>
            <ecNumber evidence="4 8 10">3.2.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ung</name>
        <name evidence="12" type="ORF">VDA_002877</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 8 10">Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8 10">
            <text>Hydrolyzes single-stranded DNA or mismatched double-stranded DNA and polynucleotides, releasing free uracil.</text>
            <dbReference type="EC" id="3.2.2.27"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8 10">Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.27" evidence="4 8 10"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301262.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002877"/>
    <dbReference type="EnsemblBacteria" id="EEZ41845">
        <property type="protein sequence ID" value="EEZ41845"/>
        <property type="gene ID" value="VDA_002877"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0692">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1260295at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004844">
        <property type="term" value="F:uracil DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd10027">
        <property type="entry name" value="UDG-F1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00148">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002043">
        <property type="entry name" value="UDG_fam1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018085">
        <property type="entry name" value="Ura-DNA_Glyclase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005122">
        <property type="entry name" value="Uracil-DNA_glycosylase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036895">
        <property type="entry name" value="Uracil-DNA_glycosylase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11264">
        <property type="entry name" value="PTHR11264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03167">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00986">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52141">
        <property type="entry name" value="SSF52141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00628">
        <property type="entry name" value="ung"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00130">
        <property type="entry name" value="U_DNA_GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8 10" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 8 10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 8 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDG" evidence="11">
        <location>
            <begin position="46"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8 9">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ41845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="219" mass="24731" checksum="E68AF755964E74D9" modified="2010-01-19" version="1">MQSWQNFLQQQQQQEYFEQIQSYVANARQQGKVVYPPEEDVFSAFTATPLDQVKVVILGQDPYHGPDQAHGLSFSVKPGVKTPPSLANMYKELATDIDGFTIPEHGYLQSWAEQGVLLLNTVLTVEQGNAHSHAKIGWETFTDKVIEHIDQECEGVIFLLWGTHAQKKGKKINTQKHHVLKSAHPSPLSAYRGFFGCQHFSQTNTLLQAMNKTPITWQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z038</accession>
    <name>D0Z038_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glutamate-1-semialdehyde 2,1-aminomutase</fullName>
            <shortName evidence="7">GSA</shortName>
            <ecNumber evidence="7">5.4.3.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Glutamate-1-semialdehyde aminotransferase</fullName>
            <shortName evidence="7">GSA-AT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">hemL</name>
        <name evidence="9" type="ORF">VDA_002901</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(S)-4-amino-5-oxopentanoate = 5-aminolevulinate</text>
            <dbReference type="Rhea" id="RHEA:14265"/>
            <dbReference type="ChEBI" id="CHEBI:57501"/>
            <dbReference type="ChEBI" id="CHEBI:356416"/>
            <dbReference type="EC" id="5.4.3.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; 5-aminolevulinate from L-glutamyl-tRNA(Glu): step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.4.3.8" evidence="7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301305.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002901"/>
    <dbReference type="EnsemblBacteria" id="EEZ41869">
        <property type="protein sequence ID" value="EEZ41869"/>
        <property type="gene ID" value="VDA_002901"/>
    </dbReference>
    <dbReference type="GeneID" id="57340807"/>
    <dbReference type="eggNOG" id="COG0001">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="493793at2"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00317"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042286">
        <property type="term" value="F:glutamate-1-semialdehyde 2,1-aminomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00375">
        <property type="entry name" value="HemL_aminotrans_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004639">
        <property type="entry name" value="4pyrrol_synth_GluAld_NH2Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00713">
        <property type="entry name" value="hemL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7 9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6 7" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="4 7 8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="7">
        <location>
            <position position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="430" mass="45864" checksum="8ADDD1A6208DA8B6" modified="2010-01-19" version="1">MSKSSDLFAKAQRTIPGGVNSPVRAFAGVGGTPLFIERADGAYIFDADGKAYIDYVGSWGPMILGHNHTAIRDAVIEAARNGLSFGAPTEMEITMAEMVSRLVPSMEMVRMVSSGTEATMSAIRLARGFTGRDKIIKFEGCYHGHADCLLVKAGSGALTLGQPSSPGVPEDFAKHTLTCTYNNLESVREAFASHPDQIACIIVEPVAGNMNCIPPVAGFLEGLREICDEFGALLIFDEVMTGFRVATGGAQGHYNIKPDLTTLGKVIGGGMPVGAFGGRREVMEYIAPTGPVYQAGTLSGNPVAMAAGHACLTVLTEEGNEARLANTTKRLAEGFKAAADKHGIPLLVHQVGGMFGFFFTDQEQVTCYEEVAKCDVERFKHFFHLMLDKGVYLAPSAFEASFTSLAHNSREIDATLEAAELSFAELAKMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z080</accession>
    <name>D0Z080_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphate transport regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002943</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0111 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002943"/>
    <dbReference type="EnsemblBacteria" id="EEZ41911">
        <property type="protein sequence ID" value="EEZ41911"/>
        <property type="gene ID" value="VDA_002943"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1392">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002727">
        <property type="entry name" value="DUF47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038078">
        <property type="entry name" value="PhoU-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018445">
        <property type="entry name" value="Put_Phosphate_transp_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36536">
        <property type="entry name" value="PTHR36536"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01865">
        <property type="entry name" value="PhoU_div"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00153">
        <property type="entry name" value="TIGR00153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="196" mass="22518" checksum="FF5C2E3F2333918D" modified="2010-01-19" version="1">MLVPFFEACHAGEWDQATTLREQISQLEKDADVLKREIRLKLPRGLFMPVDRTDMLGLLTQQDKLANLSKDIAGRVLGRKLQIPEIMYPDFLAYVRRCLDAADQARRVINELDELLETGFKGREVTLVAEMINQLDVIEDDTDSMQIKLRQQLMSIEDQHSPVDVMFLYKILEWVGGIADQAQRVGSRLEIMLSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z083</accession>
    <name>D0Z083_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">General secretion pathway protein B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002946</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301396.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002946"/>
    <dbReference type="EnsemblBacteria" id="EEZ41914">
        <property type="protein sequence ID" value="EEZ41914"/>
        <property type="gene ID" value="VDA_002946"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2054239at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032389">
        <property type="entry name" value="GspB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16537">
        <property type="entry name" value="T2SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="300" mass="32764" checksum="9B4BC41B067E5951" modified="2010-01-19" version="1">MSNILTAIKASEKERQNHANASVSPIIHPMKTIKEQHKAKNSWLVPLLIAVVPATCVVGYKLYAQQSHTVTASVSPASSSTSHEEISTLSEVAVVTKPKNAPVRVNKDIEFLSYPVLTTEPLPQGNSDYYAPPAEVSAPAEPAMYAGNYGESATTDYDSHSSEPVKTAPQDPYQLDNLDFSGVDPKLAQQLKSAIAATDGQTFSDKELDRTGDEQVKIAKHKAIPIADLPVTVQNKLPSMNFQQHIYSSKPQNRWVKVNGQERHEGDTIASGVVLKKIEQRDVILGFDGYDIAMPSLSEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z094</accession>
    <name>D0Z094_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative LuxZ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_002957</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002957"/>
    <dbReference type="EnsemblBacteria" id="EEZ41925">
        <property type="protein sequence ID" value="EEZ41925"/>
        <property type="gene ID" value="VDA_002957"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1802">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011711">
        <property type="entry name" value="GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008920">
        <property type="entry name" value="TF_FadR/GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07729">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00895">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48008">
        <property type="entry name" value="SSF48008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="4">
        <location>
            <begin position="4"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="217" mass="25172" checksum="37ED154617EEF996" modified="2010-01-19" version="1">MSSPTLTNQVMEVIRQDILLGELAPGQKLVVADLKERYNVGASPIREALVQLSWRKYVKFAPQKGCWVAPVSIAELEDLFNTNLLLSRELLTRSIANGDESWELNILTTYHKLSRVNPAAADIDYNEWDQRHSDFHLALMAGSNSPVMMALYREVYEQIERYRHIWLSRSRGYEHRYQDNGEHEAMMKAVLSRNTEEALRLLNKHFQRAIETIKPFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0H2</accession>
    <name>D0Z0H2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">DNA mismatch repair protein MutL</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">mutL</name>
        <name evidence="9" type="ORF">VDA_003036</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the DNA mismatch repair MutL/HexB family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301657.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003036"/>
    <dbReference type="EnsemblBacteria" id="EEZ42003">
        <property type="protein sequence ID" value="EEZ42003"/>
        <property type="gene ID" value="VDA_003036"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0323">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="764332at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032300">
        <property type="term" value="C:mismatch repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1540.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00149">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014762">
        <property type="entry name" value="DNA_mismatch_repair_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020667">
        <property type="entry name" value="DNA_mismatch_repair_MutL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002099">
        <property type="entry name" value="DNA_mismatch_repair_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013507">
        <property type="entry name" value="DNA_mismatch_S5_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038973">
        <property type="entry name" value="MutL/Mlh/Pms"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014790">
        <property type="entry name" value="MutL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042120">
        <property type="entry name" value="MutL_C_dimsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042121">
        <property type="entry name" value="MutL_C_regsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037198">
        <property type="entry name" value="MutL_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073">
        <property type="entry name" value="PTHR10073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01119">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08676">
        <property type="entry name" value="MutL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01340">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00853">
        <property type="entry name" value="MutL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118116">
        <property type="entry name" value="SSF118116"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00585">
        <property type="entry name" value="mutl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00058">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4 5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA_mis_repair" evidence="8">
        <location>
            <begin position="212"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="domain" description="MutL_C" evidence="7">
        <location>
            <begin position="506"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="372"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ42003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="687" mass="76754" checksum="FA4B1FBC5F9A0409" modified="2010-01-19" version="1">MPIQILPARLANQIAAGEVVERPASVVKELVENSLDAGATRIDIDIDKGGSRTIRIRDNGKGIPKDELGLALSRHATSKISSLDDLEAIMSLGFRGEALASISSVARLTLTSRTAEQEEAWSAYAEGRDMAVQLKPAAHPVGTTVEVLDLFFNTPARRKFLRAEKTEFAHIDELIKRIALSRFDVNITLRHNGKVIRQYRVAQTQAQKERRLATACGQGFLQHALVVELTHGDLKLSGWICSSSGARSQNDIQYCYVNGRMMKDKLINHAIRQAYESSLAPEQYAAYVLFIDLNPHDVDVNVHPAKHEVRFHQARLVHDFIYQGIQSALQQSDDFIEIQSPQRLSAKANIDSEYSHHAVPDATYQAIEQTPDYPNKQPAKQWREQTHYETGSTKTAREISNHSQPPSDYRSEKQGAIINTPSRHYGTTNYRAEGGPSPAEVAAYQRLIQTPDAVEERALDTTFNDAHMNSPTVTESNVWQEYAPSMPEPIRQHSSVSSEVEGLGKALVIVEKQYLVVSRNQNLALLSLEVAQNLRIQGQLKLAQSEGLKPQPLLIPHSIPVSPELLESAQQHQALLQKLGIQLKAKGKQSLIIMSVCMPLRQQNLQQLIPNLLTYLGSIAEDPTQQGWDKLLDWFAQQCVVAQEQYSLSQAIQLVTELEQLWGAQLTDHYDRLLRSVDLHTAIEAFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0J7</accession>
    <name>D0Z0J7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Multidrug resistance protein NorM</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Na(+)/drug antiporter</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_003061</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301725.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003061"/>
    <dbReference type="EnsemblBacteria" id="EEZ42028">
        <property type="protein sequence ID" value="EEZ42028"/>
        <property type="gene ID" value="VDA_003061"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0534">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="216729at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006603">
        <property type="entry name" value="DinF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="53"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="101"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="173"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="204"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="263"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="289"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="318"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="360"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="393"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="421"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00030855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ42028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="452" mass="48802" checksum="750360B9468288C0" modified="2010-01-19" version="1">MATEPRLDKHGLLSEPIPDVLRRLTIPMIFGMVAILLFNLVDTFFVSLLGTQALAAVSFTFPITFALNSITMGVSVGISTSLGRLLGRGDSQSAARFTTHGLLLALVLMSIAAMIGFFTIDPLFTLLGAEPSLLPIIHQYMSVWYLAIPLLVIPMAGNSAIRATGDAKSPAKIMMLAGLINGILDPLLIFGYGPFPELGVKGAAISSGISWAVALALSLYLLNKREKLLTRPDRKWLSADWKQILHVGTPAALSNALNPISGALLMALLATQGTVSVAAYGAAMRIESLLVIVMMSLGSVLMPFMAQNLGADNPKRAFAALFTAMKFAIVFQMLVFIAMVPLSWPLSSLFSQDNAVRDQLWHYLLVVPVSYGLQAVCMLLISALNALHKTTHALIWNLLRLFGFLLPLAWLGCYFDGTEGLFIGITIANIICGILAFVYAHRLRQTTLVNDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0L8</accession>
    <name>D0Z0L8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">Phosphoribosylamine--glycine ligase</fullName>
            <ecNumber evidence="2 7">6.3.4.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">GARS</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Glycinamide ribonucleotide synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Phosphoribosylglycinamide synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">purD</name>
        <name evidence="10" type="ORF">VDA_003082</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>5-phospho-beta-D-ribosylamine + ATP + glycine = ADP + H(+) + N(1)-(5-phospho-beta-D-ribosyl)glycinamide + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17453"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:58681"/>
            <dbReference type="ChEBI" id="CHEBI:143788"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Purine metabolism; IMP biosynthesis via de novo pathway; N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the GARS family.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.13" evidence="2 7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301807.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003082"/>
    <dbReference type="EnsemblBacteria" id="EEZ42049">
        <property type="protein sequence ID" value="EEZ42049"/>
        <property type="gene ID" value="VDA_003082"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0151">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="932854at2"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00125"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004637">
        <property type="term" value="F:phosphoribosylamine-glycine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009113">
        <property type="term" value="P:purine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00138">
        <property type="entry name" value="GARS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020561">
        <property type="entry name" value="PRibGlycinamid_synth_ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000115">
        <property type="entry name" value="PRibGlycinamide_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020560">
        <property type="entry name" value="PRibGlycinamide_synth_C-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037123">
        <property type="entry name" value="PRibGlycinamide_synth_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020559">
        <property type="entry name" value="PRibGlycinamide_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020562">
        <property type="entry name" value="PRibGlycinamide_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43472">
        <property type="entry name" value="PTHR43472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01071">
        <property type="entry name" value="GARS_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02843">
        <property type="entry name" value="GARS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02844">
        <property type="entry name" value="GARS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01210">
        <property type="entry name" value="GARS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="SSF51246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00877">
        <property type="entry name" value="purD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00184">
        <property type="entry name" value="GARS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="9">
        <location>
            <begin position="109"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ42049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="428" mass="45742" checksum="346891F7B699D05A" modified="2010-01-19" version="1">MQVLIIGNGGREHALAWKVAQNPEVSQIFVAPGNAGTALEPKVTNVAIAVEDIAALVAFAQELQIELTIVGPEAPLVLGVVDAFQAAGLAIFGPSQAASQLEGSKAFTKDFLARHQIPTAQYQNFTEIEPALAYLRQQGAPIVVKADGLAAGKGVIVAMTLQEAEDAVRDMLAGNAFGEAGHRVVIEEFLDGEEASFIVMVDGEHVLPMATSQDHKRVGNGDTGPNTGGMGAYSPAPVVTDEIHQRVMDEVIYPTVRGMAAEGNPYTGFLYAGLMIMNDGTPKVIEYNCRFGDPETQPIMLRLQSDLVELCQAAIDGKLNHCQSQWDPRAAIGVVLAAGGYPGHYHKGDVICGLPQQEIAGEKVFHAGTCELDGQVVTNGGRVLCATAMGDTVQQAQQRAYQLAQQIDWDGMFYREDIGYRAINREQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0M3</accession>
    <name>D0Z0M3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_003087</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301821.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003087"/>
    <dbReference type="EnsemblBacteria" id="EEZ42054">
        <property type="protein sequence ID" value="EEZ42054"/>
        <property type="gene ID" value="VDA_003087"/>
    </dbReference>
    <dbReference type="GeneID" id="57340435"/>
    <dbReference type="eggNOG" id="COG3068">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1327644at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1590.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007338">
        <property type="entry name" value="DUF416"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023381">
        <property type="entry name" value="YP001051499.1-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04222">
        <property type="entry name" value="DUF416"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ42054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="195" mass="22454" checksum="35AFA175769E09B1" modified="2010-01-19" version="1">MLKNPIQLRLEKLEPWQHLTFMASLCERMYPNYAFFCAETDFADARQYRSILDSIWELLTVKSAKINFENQLEKLEELVPVADDFDLYAVNPAIDACMALADLLHALLDRDLMLETVLKISSLSVDTVADLEQAREGIEITNDNQKQCEAVCVEWDMQWAIFRALKEAEKRDIELIKGLRRELREDGVSNIGIAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0M7</accession>
    <name>D0Z0M7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA-directed RNA polymerase subunit beta'</fullName>
            <shortName evidence="7">RNAP subunit beta'</shortName>
            <ecNumber evidence="7">2.7.7.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">RNA polymerase subunit beta'</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Transcriptase subunit beta'</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rpoC</name>
        <name evidence="12" type="ORF">VDA_003091</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7 8">
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="7">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the RNA polymerase beta' chain family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301833.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003091"/>
    <dbReference type="EnsemblBacteria" id="EEZ42058">
        <property type="protein sequence ID" value="EEZ42058"/>
        <property type="gene ID" value="VDA_003091"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0086">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="4421at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.860.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01322">
        <property type="entry name" value="RNApol_bact_RpoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045867">
        <property type="entry name" value="DNA-dir_RpoC_beta_prime"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012754">
        <property type="entry name" value="DNA-dir_RpoC_beta_prime_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000722">
        <property type="entry name" value="RNA_pol_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006592">
        <property type="entry name" value="RNA_pol_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007080">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007066">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042102">
        <property type="entry name" value="RNA_pol_Rpb1_3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007083">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007081">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044893">
        <property type="entry name" value="RNA_pol_Rpb1_clamp_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038120">
        <property type="entry name" value="Rpb1_funnel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376">
        <property type="entry name" value="PTHR19376"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04997">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00623">
        <property type="entry name" value="RNA_pol_Rpb1_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04983">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05000">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04998">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00663">
        <property type="entry name" value="RPOLA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02386">
        <property type="entry name" value="rpoC_TIGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 7 8" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 7 8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 7 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="RPOLA_N" evidence="11">
        <location>
            <begin position="235"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1363"/>
            <end position="1384"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="191"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="460"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="462"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="464"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="815"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="889"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="896"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="899"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ42058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="1405" mass="155184" checksum="DF341EE1CA711047" modified="2010-01-19" version="1">MKDLLKFLKAQHKTEEFDAIKIGLASPDMIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIELASPVAHIWFLKSLPSRIGLLMDMPLRDIERVLYFESYVVIEPGMTNLERSQLLSEEQYLDALEEWGDEFDAKMGAEAVKALLANMDLNAEIELMREELEETNSETKRKKLTKRLKLVEAFVQSGNNPEWMILSVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQESVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYGKLETRGLATTIKAAKKMVEREEAVVWDILDEVIREHPVMLNRAPTLHRLGIQAFEPILIEGKAIQLHPLVCAAYNADFDGDQMAVHLPLTLEAQLEARALMMSTNNILSPASGDPIIVPSQDVVLGLYYMTRDMINAKGEGMYLAGSAEAEKAYRTGSAALHARVKVRITEYKKDEQGNLTPETKLVDTTVGRAMLWTIVPKGLPYSLVNTEALGKKQISKLLNTCYRELGMKETVVFADQIMYTGFAYAALSGVSVGIDDMVVPEAKYTKIAEAEAEVAEIQEQFQSGLVTAGERYNKVIDIWATANEQVAKAMMDNLSFETVINRDGEEEQQKSFNSVYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDVVITADDCGTHGGISMMPLIEGGDVKEALRDRVLGRVVVEDVLKPGTEEVLIPRNTLIDEKWCDIIDANSVDLVKVRSVVTCENDFGCCKLCYGRDLARGHLVNTGEAVGVVAAQSIGEPGTQLTMRTFHIGGAASAAAAENSIQVKNNGSVKLQNAKFVINGEGKLVITSRASEMTIIDEFGRTKENYKLPYGSHLTKNDGDEVKAGEVIANWDPHTMPIITEVAGRIQFVDLIDGVTVSRQTDELTGLSMITVLDAAERTGAGKDMRPTVKLVDENGNDVMISGTEIPAQYFLPGKAIIQLDDGALVGIGDTLARIPQASGGTKDITGGLPRVADLFEARKPKEPAILAEITGTVSFGKETKGKRRLILTPAEGQPYEEMIPKWRQLNVFEGDKVEKGDVIADGPESPHDILRLRGVFAVAEYIVNEVQEVYRLQGVKINDKHIETIIRQMLRKVTITAPGDSEFLEGEQVEYSRVTIANRQLEAEGKTPAAYARDLLGITKASLATESFISAASFQETTRVLTEAAVSGKRDDLRGLKENVIVGRLIPAGTGFAHHQRRQRSRDAEFEPVAPQIDAEQASQDLAALLNAGLSDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0P6</accession>
    <name>D0Z0P6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATPase of the AAA+ class</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003110"/>
    <dbReference type="EnsemblBacteria" id="EEZ42077">
        <property type="protein sequence ID" value="EEZ42077"/>
        <property type="gene ID" value="VDA_003110"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031GYK">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009867">
        <property type="entry name" value="DUF1422"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07226">
        <property type="entry name" value="DUF1422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="85" mass="9607" checksum="7DFD306EB3A841DC" modified="2010-01-19" version="1">MIAFGMAVYCLYQEYLRKPMVEGTPAVATACFFIGAFGYSGFQRAMTPEMGSNFISLMIALVLLFWVTYKLGIMEGKKEEIQEQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0S8</accession>
    <name>D0Z0S8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF2489 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003142</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003142"/>
    <dbReference type="EnsemblBacteria" id="EEZ42109">
        <property type="protein sequence ID" value="EEZ42109"/>
        <property type="gene ID" value="VDA_003142"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG50332QM">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019617">
        <property type="entry name" value="DUF2489"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10675">
        <property type="entry name" value="DUF2489"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2489" evidence="1">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="84" mass="9945" checksum="53B88FD2F1FC0CA3" modified="2010-01-19" version="1">MSEISIRLFKLMEALQHDKAVDFAAQYPALHELYQVVKDMPRSEARRNIEKRQRMRLDLDRMKAEARLVDDIKQELNSILAMKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0Z7</accession>
    <name>D0Z0Z7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Protein YihD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_003211</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302176.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003211"/>
    <dbReference type="EnsemblBacteria" id="EEZ42178">
        <property type="protein sequence ID" value="EEZ42178"/>
        <property type="gene ID" value="VDA_003211"/>
    </dbReference>
    <dbReference type="GeneID" id="57340379"/>
    <dbReference type="eggNOG" id="COG3084">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1935232at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1580.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009383">
        <property type="entry name" value="DUF1040"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038134">
        <property type="entry name" value="YihD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06288">
        <property type="entry name" value="DUF1040"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ42178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="88" mass="10248" checksum="A58987E2D262EE92" modified="2010-01-19" version="1">MKTHRVNELIELLHPEWQKDPDLNLVEFLLKLAQEAQYTGKLEDLTDDVLIYHLKMRNSEKDAMIPGLAKDCEDDFKTAILRARGIIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z102</accession>
    <name>D0Z102_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4365 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003216</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302189.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ42183">
        <property type="protein sequence ID" value="EEZ42183"/>
        <property type="gene ID" value="VDA_003216"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG50321H4">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2012520at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025375">
        <property type="entry name" value="DUF4365"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14280">
        <property type="entry name" value="DUF4365"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4365" evidence="1">
        <location>
            <begin position="18"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="604" mass="69500" checksum="F0074E15F1D9ADC8" modified="2010-01-19" version="1">MNAGEIGAAAGRIFNYKAPLNWIIRSQEDQDDYGIDCEIELKDSSGKALGQESLFKIQLKGQENCSFIDEGQKLSFSVFRARLQYYLEFNIPVILVVVEVSSEEIYWVSVTDNKEILEKVRDSSTDSLTVHLPVENKLERNDSAAFDKLLVAVQECWDYLSLRDLKLAVNNCKTLPPEALNTCIEQVGDALFKAYHIKLDRLLLARSFDELYQQASDIIQSRIVPTKDRFLAALYFDYAFKVAPYKRVKNEQIEEQLKLCEYLIVCAREQKQSVYRLTAIAKARSALFSIQVEKLNAQHHSNENFKSDSFEYLFMNREIHKQYHEACAQLQKIINMCHRLINLSQFNILADLMCDVALSIGVFKTIHNARGSNEAIVFLDEWIEKMLHTVLMYSSIVSDIRKIEQLYLMVNLQSELKTIVRFDVKSLIIEHCPSAENLLDALDNVMASKEEPKPLYEASIEEQKQFFAEMAKNLGMDPDDPASREGQFIAIGLANYDPTNIIGHCEYMFVDYRPRGMIAQQLGMHSLSMPIMTCLKHKHTVGTGNLLIKVFDNSKGPEFALGFKQNHCDKCSDCSPRADDWIWSLKWQHEERKKHTEWLDKIDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z109</accession>
    <name>D0Z109_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="14 15">Dihydroxy-acid dehydratase</fullName>
            <shortName evidence="15">DAD</shortName>
            <ecNumber evidence="14 15">4.2.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">ilvD</name>
        <name evidence="16" type="ORF">VDA_003223</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>(2R)-2,3-dihydroxy-3-methylbutanoate = 3-methyl-2-oxobutanoate + H2O</text>
            <dbReference type="Rhea" id="RHEA:24809"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:49072"/>
            <dbReference type="EC" id="4.2.1.9"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:24810"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>(2R,3R)-2,3-dihydroxy-3-methylpentanoate = (S)-3-methyl-2-oxopentanoate + H2O</text>
            <dbReference type="Rhea" id="RHEA:27694"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:35146"/>
            <dbReference type="ChEBI" id="CHEBI:49258"/>
            <dbReference type="EC" id="4.2.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="15">Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 15">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="13 15">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 3/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="12 15">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 3/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the IlvD/Edd family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.9" evidence="14 15"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302206.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003223"/>
    <dbReference type="EnsemblBacteria" id="EEZ42190">
        <property type="protein sequence ID" value="EEZ42190"/>
        <property type="gene ID" value="VDA_003223"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0129">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="193579at2"/>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00057"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00061"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004160">
        <property type="term" value="F:dihydroxy-acid dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00012">
        <property type="entry name" value="IlvD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042096">
        <property type="entry name" value="Dihydro-acid_dehy_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004404">
        <property type="entry name" value="DihydroxyA_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000581">
        <property type="entry name" value="DiOHA_6PGluconate_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020558">
        <property type="entry name" value="DiOHA_6PGluconate_deHydtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037237">
        <property type="entry name" value="IlvD/EDD_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00920">
        <property type="entry name" value="ILVD_EDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143975">
        <property type="entry name" value="SSF143975"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00110">
        <property type="entry name" value="ilvD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00886">
        <property type="entry name" value="ILVD_EDD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00887">
        <property type="entry name" value="ILVD_EDD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 15" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3 15" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 15" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="7 15" id="KW-0408">Iron</keyword>
    <keyword evidence="8 15" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9 15 16" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 15" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="15">
        <location>
            <position position="517"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" description="via carbamate group" evidence="15">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="491"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-carboxylysine" evidence="15">
        <location>
            <position position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00029436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00029437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00029490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EEZ42190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="613" mass="65770" checksum="4EC708BF572D7012" modified="2010-01-19" version="1">MPTYRSATTTHGRNMAGARALWRATGVKDEDFGKPIIAVVNSFTQFVPGHVHLKDLGQLVAKEIEQAGGIAKEFNTIAVDDGIAMGHGGMLYSLPSRELIADSVEYMVNAHCADAMVCISNCDKITPGMLMASLRLNIPVIFVSGGPMEAGKTQLSDQIIKLDLVDAMIQGADPNVSDAQSEQIERSACPTCGSCSGMFTANSMNCLTEALGLSQPGNGSLLATHSDRKQLFLNAGRRIVELTKRYYEQDDPQALPRNIANKAAFENAMALDIAMGGSTNTVLHLLAAAQEGEVDFTMNDIDRMSRQVPHLCKVAPSTQQYHMEDVHRAGGVYGILGELDRAGLLNNQCVNVLGQTVADSLRQFDITQTQDPAIIDFYRAGPAGIRTTEAFSQSCRWDKVDDDRQLGCIRRQQDAYSQDGGLAVLFGNMALDGCIVKTAGVDESCLTFSGPAIVFESQESAVEGILGGEVKAGDVVVIRYEGPKGGPGMQEMLYPTTYLKSMGLGKSCALITDGRFSGGTSGLSIGHVSPEAANGGTIGLIENGDNINIDIPNRTIELNVDPLQLAQRREQAEQRGWKPIDRQRQVSFALKAYANLATSADKGAVRDKSKLGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z116</accession>
    <name>D0Z116_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">ATP synthase subunit beta</fullName>
            <ecNumber evidence="12">7.1.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">ATP synthase F1 sector subunit beta</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">F-ATPase subunit beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">atpD</name>
        <name evidence="14" type="ORF">VDA_003230</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:57720"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.1.2.2"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cell membrane</location>
            <topology evidence="12">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.</text>
    </comment>
    <dbReference type="EC" id="7.1.2.2" evidence="12"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302228.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003230"/>
    <dbReference type="EnsemblBacteria" id="EEZ42197">
        <property type="protein sequence ID" value="EEZ42197"/>
        <property type="gene ID" value="VDA_003230"/>
    </dbReference>
    <dbReference type="GeneID" id="57340363"/>
    <dbReference type="eggNOG" id="COG0055">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="430176at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1140.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01347">
        <property type="entry name" value="ATP_synth_beta_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005722">
        <property type="entry name" value="ATP_synth_F1_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036121">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024034">
        <property type="entry name" value="ATPase_F1/V1_b/a_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50615">
        <property type="entry name" value="SSF50615"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01039">
        <property type="entry name" value="atpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="5 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 12" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 12" id="KW-0139">CF(1)</keyword>
    <keyword evidence="4 12" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-1278">Translocase</keyword>
    <keyword evidence="1 12" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AAA" evidence="13">
        <location>
            <begin position="143"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="151"/>
            <end position="158"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEZ42197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="468" mass="50777" checksum="7EF55CC9B72C29E2" modified="2010-01-19" version="1">MATGKIVQIIGAVVDVEFPQDSVPQVYDALHVDAKEQGTLVLEVQQQLGGGVVRGIAMGTSDGLRRGLSVENTGRPIEVPVGTATLGRIMNVLGDAIDERGDIGEEERYAIHRAAPSYEEQSNTTEMLETGVKVIDLICPFAKGGKIGLFGGAGVGKTVNMMELINNIAIQHSGLSVFAGVGERTREGNDFYFEMQEAGVVNVENPAESKVAMVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLLFIDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKSGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLSRQIASLGLYPAIDPLDSTSRMLDPLVVGQEHYDIARGVQSILQRYKELKDIIAILGMDELSEDDKLSVSRARKIERFLTQPYHVAEVFTGQPGIYVPLKDTLRSFKGLLAGEYDDIPEQAFMYCGAIEEVLEKAKTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z158</accession>
    <name>D0Z158_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Thiamine-phosphate synthase</fullName>
            <ecNumber evidence="8">2.5.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Thiamine-phosphate pyrophosphorylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">VDA_003272</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 2 H(+) = CO2 + diphosphate + thiamine phosphate</text>
            <dbReference type="Rhea" id="RHEA:47848"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:62890"/>
            <dbReference type="EC" id="2.5.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 8">
            <text>2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 2 H(+) = CO2 + diphosphate + thiamine phosphate</text>
            <dbReference type="Rhea" id="RHEA:47844"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:62899"/>
            <dbReference type="EC" id="2.5.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 8">
            <text>4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 4-methyl-5-(2-phosphooxyethyl)-thiazole + H(+) = diphosphate + thiamine phosphate</text>
            <dbReference type="Rhea" id="RHEA:22328"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:58296"/>
            <dbReference type="EC" id="2.5.1.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4 9">Cofactor biosynthesis; thiamine diphosphate biosynthesis; thiamine phosphate from 4-amino-2-methyl-5-diphosphomethylpyrimidine and 4-methyl-5-(2-phosphoethyl)-thiazole: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the thiamine-phosphate synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.3" evidence="8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302350.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003272"/>
    <dbReference type="EnsemblBacteria" id="EEZ42239">
        <property type="protein sequence ID" value="EEZ42239"/>
        <property type="gene ID" value="VDA_003272"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0352">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="461201at2"/>
    <dbReference type="UniPathway" id="UPA00060">
        <property type="reaction ID" value="UER00141"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004789">
        <property type="term" value="F:thiamine-phosphate diphosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00564">
        <property type="entry name" value="TMP_TenI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036206">
        <property type="entry name" value="ThiamineP_synth_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022998">
        <property type="entry name" value="ThiamineP_synth_TenI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034291">
        <property type="entry name" value="TMP_synthase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02581">
        <property type="entry name" value="TMP-TENI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51391">
        <property type="entry name" value="SSF51391"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00693">
        <property type="entry name" value="thiE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="5 8 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TMP-TENI" evidence="11">
        <location>
            <begin position="216"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="381"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ42239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="415" mass="46376" checksum="2EE2D81E092D7B24" modified="2010-01-19" version="1">MSALRLSENLMPLLMHIDPILATAEQFGLGEKVDISLVDHEAVFIRSAQQNWQVVFNAHHQDQSSDVLLRVLDQWLAPYPSLDEIKQKVLNEPQLVVSGLPVADGFVDLWYHNGKVEMTFCHHLGANEPHRAMLLAALALDYPLQDACVLARAYARRYLDQNRDRLLHWPDCLTLFPRVVTRTHEQALTLLGEQSSPVCFEPVNREDFTLYAVVDSATWIDKVLSCGVTTAQLRIKESATTDLTAQISQAVNSGHTYHSQVFINDYWQQAIEAEAFGVHLGQEDLDTADLTMIAQAQLRLGISTHGYYEILRAIELKPSYIALGHVFATTTKEMESSPQGVVRLALYQKLLTGVVPTVAIGGIDLTNIEQVLRCEVDSVAVVRAITQAENVEEAIKRLKEKIDQYRGGLDDAIVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1H7</accession>
    <name>D0Z1H7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative Na+/H+ exchange protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003391</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ42358">
        <property type="protein sequence ID" value="EEZ42358"/>
        <property type="gene ID" value="VDA_003391"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0475">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="739373at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="111"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="197"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="247"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="288"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="331"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="357"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="392" mass="43859" checksum="E65EA93133D56A00" modified="2010-01-19" version="1">MRKVIVYSLLLIIGLFGSQLLPNIFTHYNQLQPLIMISTMTALSYIMINVGREFEIDKNNLKQYRWDYIVAMTTATFPWIAVVVYFIFVLFPAELWTNADAWKETLVIGRFAAPTSAGVLFAMLAAAGLGATWMFSKARILAIFDDLDTVLLMIPLSILVVGWQPALGVTLFLMFALLILGYRYLHQWSIPSSARSILFYSVIIAVVCELFYLRSGVHFEVLLPAFVLGCLMKSQHESKQDEKVSTWIAAIFMVLVGLSLPPLFNAVSETVATTSLSMAMLAMGMKEIIYHVLVISVLANLGKMFPLFCYRKEATLRERLALSISMWPRGEVGAGVLMISLGYGFGGPMITISMLSLALNLVMTGLFIMVVRYLIVTPTSQSEEERYEESRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1L8</accession>
    <name>D0Z1L8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidyl-prolyl cis-trans isomerase</fullName>
            <ecNumber evidence="5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_003432</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the FKBP-type PPIase family.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302700.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003432"/>
    <dbReference type="EnsemblBacteria" id="EEZ42399">
        <property type="protein sequence ID" value="EEZ42399"/>
        <property type="gene ID" value="VDA_003432"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0545">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1861282at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000774">
        <property type="entry name" value="PPIase_FKBP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036944">
        <property type="entry name" value="PPIase_FKBP_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01346">
        <property type="entry name" value="FKBP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="7">
        <location>
            <begin position="177"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="266"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ42399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="290" mass="31276" checksum="9394273ED0E86229" modified="2010-01-19" version="1">MKPVLKMSVLAATIFLAVGCQDENKADTKPAEPVKAEQTVSAAAPAEKATAVEFKTEDQKAAYAIGASLAQYLAANLDQQQELGIKLDRKDVLAGVEDVFADKSRLTPEQTQQALQDLDKRVSEIVQQKAKQESEQNLKAGTEFREKFAKEQGVVTTKSGLMYKIEKEGTGPKPVATDTVEVHYKGTLIDGTEFDSSYKRNQTATFPLNQVIPGWTEGVQLMPVGSKFEFVIPPQLAYGSQANPSIPANSTLVFQVELVGIKGKTEKPATEAAKEVTKAASQAESAAKAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1N4</accession>
    <name>D0Z1N4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">30S ribosomal protein S17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rpsQ</name>
        <name evidence="4" type="ORF">VDA_003448</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the universal ribosomal protein uS17 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302801.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003448"/>
    <dbReference type="EnsemblBacteria" id="EEZ42415">
        <property type="protein sequence ID" value="EEZ42415"/>
        <property type="gene ID" value="VDA_003448"/>
    </dbReference>
    <dbReference type="GeneID" id="57340095"/>
    <dbReference type="eggNOG" id="COG0186">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2035880at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01345_B">
        <property type="entry name" value="Ribosomal_S17_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019984">
        <property type="entry name" value="Ribosomal_S17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000266">
        <property type="entry name" value="Ribosomal_S17/S11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10744">
        <property type="entry name" value="PTHR10744"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00366">
        <property type="entry name" value="Ribosomal_S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00973">
        <property type="entry name" value="RIBOSOMALS17"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03635">
        <property type="entry name" value="uS17_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 3" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ42415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="84" mass="9677" checksum="8E26F22025C35BF4" modified="2010-01-19" version="1">MSEQIRTQLGRVVSDKGDKTIVVAIERMVKHPIYGKFIKRTTKLHAHDENNECGLGDTVEIRECRPMSKTKSWTLVRLVEKARI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1P2</accession>
    <name>D0Z1P2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">30S ribosomal protein S5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rpsE</name>
        <name evidence="12" type="ORF">VDA_003456</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.</text>
    </comment>
    <comment type="function">
        <text evidence="8">With S4 and S12 plays an important role in translational accuracy.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.</text>
    </comment>
    <comment type="domain">
        <text evidence="8">The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8 10">Belongs to the universal ribosomal protein uS5 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302820.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003456"/>
    <dbReference type="EnsemblBacteria" id="EEZ42423">
        <property type="protein sequence ID" value="EEZ42423"/>
        <property type="gene ID" value="VDA_003456"/>
    </dbReference>
    <dbReference type="GeneID" id="57340087"/>
    <dbReference type="eggNOG" id="COG0098">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1505038at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01307_B">
        <property type="entry name" value="Ribosomal_S5_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000851">
        <property type="entry name" value="Ribosomal_S5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005712">
        <property type="entry name" value="Ribosomal_S5_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005324">
        <property type="entry name" value="Ribosomal_S5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013810">
        <property type="entry name" value="Ribosomal_S5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018192">
        <property type="entry name" value="Ribosomal_S5_N_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13718">
        <property type="entry name" value="PTHR13718"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00333">
        <property type="entry name" value="Ribosomal_S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03719">
        <property type="entry name" value="Ribosomal_S5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01021">
        <property type="entry name" value="rpsE_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00585">
        <property type="entry name" value="RIBOSOMAL_S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50881">
        <property type="entry name" value="S5_DSRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6 8 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 8" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="S5 DRBM" evidence="11">
        <location>
            <begin position="10"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ42423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="165" mass="17429" checksum="10BD99685131EA71" modified="2010-01-19" version="1">MANEKTQSDLHEKLIAVNRVSKTVKGGRIFSFTALTVVGDGNGRVGFGYGKAREVPAAIQKAMEKARRNMTNVALNEGTLHHAVKGRHTGSKVYMQPASEGTGIIAGGAMRAVLEVAGVRNVLAKAYGSTNPINIVRATIDGLSGMNSPEMIAAKRGLSVKEILE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-12-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1Q6</accession>
    <name>D0Z1Q6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Outer membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_003470</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003470"/>
    <dbReference type="EnsemblBacteria" id="EEZ42437">
        <property type="protein sequence ID" value="EEZ42437"/>
        <property type="gene ID" value="VDA_003470"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2885">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07185">
        <property type="entry name" value="OmpA_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006664">
        <property type="entry name" value="OMP_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006665">
        <property type="entry name" value="OmpA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036737">
        <property type="entry name" value="OmpA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00691">
        <property type="entry name" value="OmpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01021">
        <property type="entry name" value="OMPADOMAIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103088">
        <property type="entry name" value="SSF103088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51123">
        <property type="entry name" value="OMPA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OmpA-like" evidence="3">
        <location>
            <begin position="123"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ42437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="261" mass="30352" checksum="A6C17C2D02B1BA0C" modified="2010-01-19" version="1">MTSAIMKTLFSTAWCCVLTACTLWPEPKPLSPITKEQQHQLEHYSWELKLLEARGVKLCLPAQYQKLDWLYQQAYQEFVAGFPHDAELTLQKYQFTADMIDRQMDWLEFHTHCFNHYSEVELREQLELYFAVDNQFALNRSELLPAYQQALTQAAAILKRHRHWHVKLVGHTDTQGQKHDNYHLGLTRANNVKRFLLEHGVNGHQVSVLSTGESQAVPDTHSRTMQLANRQVVAEILVSAHDKSPHRHFSLKDWPAMRTTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1V0</accession>
    <name>D0Z1V0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HPr domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003514</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003514"/>
    <dbReference type="EnsemblBacteria" id="EEZ42481">
        <property type="protein sequence ID" value="EEZ42481"/>
        <property type="gene ID" value="VDA_003514"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1925">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000032">
        <property type="entry name" value="HPr-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035895">
        <property type="entry name" value="HPr-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00381">
        <property type="entry name" value="PTS-HPr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55594">
        <property type="entry name" value="SSF55594"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51350">
        <property type="entry name" value="PTS_HPR_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HPr" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="42" mass="4465" checksum="337044F20F6F528A" modified="2010-01-19" version="1">MGLLMLESAQGQQITVSAQGEQSEQALTAICHLIEAGFDEES</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1X6</accession>
    <name>D0Z1X6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nicotinate-nucleotide diphosphorylase (carboxylating)</fullName>
            <ecNumber evidence="4">2.4.2.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Quinolinate phosphoribosyltransferase [decarboxylating]</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">VDA_003540</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the catabolism of quinolinic acid (QA).</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from quinolinate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the NadC/ModD family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.19" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303737.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003540"/>
    <dbReference type="EnsemblBacteria" id="EEZ42507">
        <property type="protein sequence ID" value="EEZ42507"/>
        <property type="gene ID" value="VDA_003540"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0157">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1718114at2"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00331"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004514">
        <property type="term" value="F:nicotinate-nucleotide diphosphorylase (carboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01572">
        <property type="entry name" value="QPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004393">
        <property type="entry name" value="NadC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027277">
        <property type="entry name" value="NadC/ModD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036068">
        <property type="entry name" value="Nicotinate_pribotase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037128">
        <property type="entry name" value="Quinolinate_PRibosylTase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002638">
        <property type="entry name" value="Quinolinate_PRibosylTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022412">
        <property type="entry name" value="Quinolinate_PRibosylTrfase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32179">
        <property type="entry name" value="PTHR32179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01729">
        <property type="entry name" value="QRPTase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02749">
        <property type="entry name" value="QRPTase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006250">
        <property type="entry name" value="NadC_ModD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51690">
        <property type="entry name" value="SSF51690"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00078">
        <property type="entry name" value="nadC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9 13" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="QRPTase_N" evidence="12">
        <location>
            <begin position="42"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="QRPTase_C" evidence="11">
        <location>
            <begin position="130"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="150"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="257"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="278"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="213"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00033102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR006250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR006250-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ42507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="295" mass="32021" checksum="2701D584D861B4CB" modified="2010-01-19" version="1">MEKNHDSAARFALLQQYLPADIERSVRDSLREDLGGVIDAERDITAALIPQESISIATIITREDGIFCGQLWADEVFRQLGGKVAIEWLVQDGEPVTANQVLCRLTGPSRLLLTGERNAMNFIQTLSGCATETARYVAQLAGTHTRLLDTRKTIPGLRSALKYAVACGGGYNHRLGVFDAYLIKENHIAACGGIKQAISQAKQLNPNKPVEVETESLAELELAIEAGADIIMLDNFSFAMMREAVALNAGRAVLENSGNVTLETLAECAATGVDYISVGALTKHIRAMDLSMRFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1X9</accession>
    <name>D0Z1X9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal RNA small subunit methyltransferase H</fullName>
            <ecNumber evidence="6">2.1.1.199</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">16S rRNA m(4)C1402 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">rRNA (cytosine-N(4)-)-methyltransferase RsmH</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rsmH</name>
        <name evidence="7" type="ORF">VDA_003543</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>cytidine(1402) in 16S rRNA + S-adenosyl-L-methionine = H(+) + N(4)-methylcytidine(1402) in 16S rRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42928"/>
            <dbReference type="Rhea" id="RHEA-COMP:10286"/>
            <dbReference type="Rhea" id="RHEA-COMP:10287"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74506"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.199"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the methyltransferase superfamily. RsmH family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.199" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303747.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003543"/>
    <dbReference type="EnsemblBacteria" id="EEZ42510">
        <property type="protein sequence ID" value="EEZ42510"/>
        <property type="gene ID" value="VDA_003543"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0275">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1272633at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071424">
        <property type="term" value="F:rRNA (cytosine-N4-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01007">
        <property type="entry name" value="16SrRNA_methyltr_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002903">
        <property type="entry name" value="RsmH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023397">
        <property type="entry name" value="SAM-dep_MeTrfase_MraW_recog"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11265">
        <property type="entry name" value="PTHR11265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01795">
        <property type="entry name" value="Methyltransf_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004486">
        <property type="entry name" value="MraW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81799">
        <property type="entry name" value="SSF81799"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00006">
        <property type="entry name" value="TIGR00006"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6 7" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="6">
        <location>
            <begin position="35"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ42510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="315" mass="34938" checksum="6F2E61928F2BF415" modified="2010-01-19" version="1">MSEQFEHVSVLLHESVDGLAIKPDGIYIDGTFGRGGHSRLILSKLGENGRLYSIDRDPQAIAEAQKIDDPRFNIIHGPFSGMEKYMEERDLIGRVDGILLDLGVSSPQLDDAERGFSFMRDGPLDMRMDPTSGQAASEWLATADASDIAWVLKEFGEERFAKRIARGIVEHREDPEKEPLTRTLQLANLIAQVSPFKDKHKHPATRSFQAIRIYINSELDEIATALNGAVNILAPGGRLSVISFHSLEDRMVKRFMRNKSKGPEIPAGLPLTEEQIKALGSADLKLASKAIKPSQNELGYNARARSSVLRLAERL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1Y0</accession>
    <name>D0Z1Y0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative cell division protein FtsL</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_003544</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003544"/>
    <dbReference type="EnsemblBacteria" id="EEZ42511">
        <property type="protein sequence ID" value="EEZ42511"/>
        <property type="gene ID" value="VDA_003544"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3116">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011922">
        <property type="entry name" value="Cell_div_FtsL"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04999">
        <property type="entry name" value="FtsL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6" id="KW-0132">Cell division</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ42511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="43" mass="5165" checksum="A8E2464F7BAB4A31" modified="2010-01-19" version="1">MDIEWRNQLLEENALAEHSRIERLAEQELKMERPTTTNEVVIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1Y8</accession>
    <name>D0Z1Y8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hypothetical hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001960</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001960"/>
    <dbReference type="EnsemblBacteria" id="EEZ40928">
        <property type="protein sequence ID" value="EEZ40928"/>
        <property type="gene ID" value="VDA_001960"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1473">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017439">
        <property type="entry name" value="Amidohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005962">
        <property type="entry name" value="Pept_M20D_amidohydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01891">
        <property type="entry name" value="amidohydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="2">
        <location>
            <begin position="229"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="429" mass="46942" checksum="BA6C6762AFD1E7A5" modified="2010-01-19" version="1">MTFFQNYDEQALSQRLMNYRREFHRYPESAWCEFFTTCRIAAHMEHHGYQLAFADEIIARSAIMGRDEESVIEAQKRALTWGADPKYLAQMDGITGLGAILDTGRDGPTVAFRFDIDAVDVMESQDDSHRPRFLGFASLAPGIAHACGHDAHTAIGLGLAELIAANKDQLCGKIKFIFQPAEEGCRAGKAIAESGWLDDVDYFLAAHVGMNVPSGTLVCDPKHFLCSSKFDLHFKGKPAHAGIEPNAGCNALAAACTSVTQMLAIPRHRDGMTRVNVGQLKAGEGRNVIPANAVLKGETRGENREINDYMYQQVERIAQGSAHIHGVNVEIQAQGEAIGLHNDTEMVNLIESIGLDAGFSDVIREKDFGASEDVGYLFDRVQHNGGKAVYCLIGSDLTAGHHNGDFDIDESRMVSGVRLFAMALMRLNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z229</accession>
    <name>D0Z229_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001878</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298862.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40846">
        <property type="protein sequence ID" value="EEZ40846"/>
        <property type="gene ID" value="VDA_001878"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2990">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="736338at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007488">
        <property type="entry name" value="DUF535"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38785">
        <property type="entry name" value="PTHR38785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04393">
        <property type="entry name" value="DUF535"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="310" mass="36216" checksum="1EF061C27361654C" modified="2010-01-19" version="1">MSSLHSSTYKQLCILSQNLHADSTGFKKVRQDVRFKFWGLMHQKTIKNLLQTFDNETLSPVLSIHPKIIKKPFKSYICAKWNTQRRVSSVQQHFQFLQHNFHADALPAIFTADGYQLAEVTDQEENIYRLFINRGQQREGSLGLSLLDSEGNRVYATTVNFETTPYRTMYIGVIQGPNEGIENRQQVIKSLTKSCHGLRPKALILEFALMLARCLNVTHIYGISNQGHIYKSWRYIGRKRSSIVTFDYDAYWQEYGAIQIDKSFYLVPTQPERKDLSQLNRNKRKLYTKRYAWLDELEQSFCQNLTPLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z243</accession>
    <name>D0Z243_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase</fullName>
            <ecNumber evidence="10">2.1.1.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Cobalamin-independent methionine synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Methionine synthase, vitamin-B12 independent isozyme</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">metE</name>
        <name evidence="13" type="ORF">VDA_001779</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>5-methyltetrahydropteroyltri-L-glutamate + L-homocysteine = L-methionine + tetrahydropteroyltri-L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:21196"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58140"/>
            <dbReference type="ChEBI" id="CHEBI:58199"/>
            <dbReference type="ChEBI" id="CHEBI:58207"/>
            <dbReference type="EC" id="2.1.1.14"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="10">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-methionine from L-homocysteine (MetE route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the vitamin-B12 independent methionine synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.14" evidence="10"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298683.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001779"/>
    <dbReference type="EnsemblBacteria" id="EEZ40747">
        <property type="protein sequence ID" value="EEZ40747"/>
        <property type="gene ID" value="VDA_001779"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0620">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="577156at2"/>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00082"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003871">
        <property type="term" value="F:5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03311">
        <property type="entry name" value="CIMS_C_terminal_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.210">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00172">
        <property type="entry name" value="Meth_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013215">
        <property type="entry name" value="Cbl-indep_Met_Synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006276">
        <property type="entry name" value="Cobalamin-indep_Met_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002629">
        <property type="entry name" value="Met_Synth_C/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038071">
        <property type="entry name" value="UROD/MetE-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08267">
        <property type="entry name" value="Meth_synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01717">
        <property type="entry name" value="Meth_synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000382">
        <property type="entry name" value="MeTrfase_B12_ind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51726">
        <property type="entry name" value="SSF51726"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01371">
        <property type="entry name" value="met_syn_B12ind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 10" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="4 10 13" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 10 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Meth_synt_1" evidence="12">
        <location>
            <begin position="7"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="domain" description="Meth_synt_2" evidence="11">
        <location>
            <begin position="434"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="region of interest" description="5-methyltetrahydropteroyltri-L-glutamate binding" evidence="10">
        <location>
            <begin position="20"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="L-homocysteine binding" evidence="10">
        <location>
            <begin position="438"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="L-methionine binding" evidence="10">
        <location>
            <begin position="438"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="5-methyltetrahydropteroyltri-L-glutamate binding" evidence="10">
        <location>
            <begin position="522"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10">
        <location>
            <position position="701"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>5-methyltetrahydropteroyltri-L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:58207"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="491"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="568"/>
        </location>
        <ligand>
            <name>5-methyltetrahydropteroyltri-L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:58207"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="606"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="612"/>
        </location>
        <ligand>
            <name>5-methyltetrahydropteroyltri-L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:58207"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="648"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="650"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="672"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="733"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF08267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ40747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="769" mass="86822" checksum="C9BBBD9D7F94A702" modified="2010-01-19" version="1">MTINKTKTHILGFPRIGKKRELKFALEKYWRQEISQSELLDVGSKIRIENWQLQQQTGLDFATVGDFAWYDHVLGTSLLLGHIPKRHQHGFPTLDTLFGIARGKTATGCGCAAGDMTKWFNTNYHYIVPEFSADDRFTVSWPQLFEEVAQAQAAGHQVKPVLLGPLSYLWLGTEKDEDPNFDRLSLLPRLIAAYQHILSKLKALGVEWVQIDEPILSLELPTNWIHSFKLTYQMLHGYSKLLLATYFDDVTSQLDKIVELNIDGIHIDAVSSPSQLSQVANAIPNHWVLSAGVINGRNVWRADLASWLEVLTPIKALLGERLWLASSCSLLHSPIELSQESKLNPEVKQWFAFAHEKCHELSLLARALDGEDEAKAQCRTYSEVIHSRQKNTEVNNSEVQQRVNNTDFSNSSRAVSFSQRKVLQQNKLQLPLYPTTTIGSFPQTGEIRTQRRDFKAGRLDKTSYDAAMKAQIRDAIARQERLGLDVLVHGEAERNDMVEYFAEHLAGFVSTQFGWVQSYGSRCVKPAIVVSDIYRSQPITLEWASYAQSLTDKPVKGMLTGPVTILAWTFPREDISKQEIANQIALALRDEVDDLQQQGIAIIQIDEPALREGLPLKESQWEAYLTWAVNAFKVAAGSAKPETQIHTHMCYSEFNHIISAVADLDADVITIETSRSDMALLGAFEAFNYPNDIGPGVYDIHSPNIPSKQAIIDLLTKAERWIEPQKLWVNPDCGLKTRNWQECEAALEVLVDAAKELRLRYHQTMLHTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z281</accession>
    <name>D0Z281_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DnaK-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001926</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298953.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001926"/>
    <dbReference type="EnsemblBacteria" id="EEZ40894">
        <property type="protein sequence ID" value="EEZ40894"/>
        <property type="gene ID" value="VDA_001926"/>
    </dbReference>
    <dbReference type="GeneID" id="57341946"/>
    <dbReference type="eggNOG" id="COG0443">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="155921at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="PTHR19375"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="611" mass="66635" checksum="C8E39540D072BA33" modified="2010-01-19" version="1">MQETQEHRYSIGIDLGTTHCVLSYVDLNDEDAAVTVMPIPQLTNPGNVEERSQLPSFMYQAHESELAPGDTALPWNAQPKAIVGAMARTLGSKTPIRLISSAKSWLCHGGVNRRDAFLPLNSPDEVAKVSPVEATQNYLEHLADAWNNAHPETPIFDQDVTITVPASFDPAARDLTAEAARNVGFKHLTLLEEPQAAVYSWIKNNDETWRDQVSVGDIVLVVDIGGGTTDLSLVAVTEDDGNLTLNRVAVGDHILLGGDNMDLALAYRLKMKLAQEGKQLQPWQVQAITHACRDAKEDLLNDSELKSVPIVVPSRGSKLLGGTLQTELTQEEVQQTLVEGFFPQTAVEEMPVQTARGALTQMGLPYAQDAAVSRHVASFLSRQSQAVEELFEKYEQVHDGFIRPTAILFNGGVLKSSLLADRLMSIINSWLTTAGSEEAKRLQGLDLDLAVASGASYYGSVRRGKGVRIRGGIASSYYVGIESAMPAIPGMEPPLEALCVAPFGMEEGSEVNVPSQEFGLIIGQPVHFKFFGSTVRREDTAGTHLDWWEPEEMEELPEIQVTLPVTEGRSAGEVVPVKLASRVTELGTLCLEAISTENGQKWQVEFDVRES</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2J3</accession>
    <name>D0Z2J3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_000644</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304946.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000644"/>
    <dbReference type="EnsemblBacteria" id="EEZ39624">
        <property type="protein sequence ID" value="EEZ39624"/>
        <property type="gene ID" value="VDA_000644"/>
    </dbReference>
    <dbReference type="GeneID" id="57342860"/>
    <dbReference type="eggNOG" id="COG0110">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1878940at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016407">
        <property type="term" value="F:acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024688">
        <property type="entry name" value="Mac_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14602">
        <property type="entry name" value="Hexapep_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12464">
        <property type="entry name" value="Mac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01266">
        <property type="entry name" value="Mac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Mac" evidence="4">
        <location>
            <begin position="5"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="184" mass="20237" checksum="7B2896F901522800" modified="2010-01-19" version="1">MKTEFEKMISGEIYHGMDPEIDTLRTEVEKQLIPLNQTTIREQRPLLESLLGKFGSDSVIRMPFSCEYGKNIFIGDQTFVNAGAVWLDNAPITIGAHVLIGPNSQFFTPTHSLDYRSRRNWETWCLPITIEDDVWIGGNVCICQGVTIGARSVVAAGSVVTSDVPPDTLVGGTPAKVIKALNND</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2J9</accession>
    <name>D0Z2J9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_000650</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0324 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39630">
        <property type="protein sequence ID" value="EEZ39630"/>
        <property type="gene ID" value="VDA_000650"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2855">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018383">
        <property type="entry name" value="UPF0324_pro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30106">
        <property type="entry name" value="PTHR30106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03601">
        <property type="entry name" value="Cons_hypoth698"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="34"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="79"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="134"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="161"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="227"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="251"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="276"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="312"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ39630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="335" mass="35797" checksum="E790BBE5ED9715B5" modified="2010-01-19" version="1">MSIYWFDYNHTIYIAIIHSMSFKKIFARLQPSDALFFIAALFCLLPFVSSPIALILGFSLASLGLVPSQFNIAAATKKLLSYSIIGLGFGIHLNEAIEASKQGLGLIVCSIFFTLILGWVVTRLMGLDKKTGHLIASGTAICGGSAIAAVAPAINAKDDEISLALATVFVLNAIALFIFPVIGHLLDMSQHAFGTWAAIAIHDTSSVVGAAGSYGDEALKTATTLKLARALWIIPVAFISALLFKGNSKKISVPFFIAFYCLAIVFAHFVPSLQPAYDMIFAFSKRLLVMCLFLIGSGITINKLRNAGAKPLLLGVILWLAIGGASLAYIEATMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2L7</accession>
    <name>D0Z2L7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Enoyl-CoA hydratase [valine degradation]/enoyl-CoA hydratase [isoleucine degradation]</fullName>
            <ecNumber evidence="3">4.2.1.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000668</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="4.2.1.17" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305004.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000668"/>
    <dbReference type="EnsemblBacteria" id="EEZ39648">
        <property type="protein sequence ID" value="EEZ39648"/>
        <property type="gene ID" value="VDA_000668"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1024">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1238555at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003860">
        <property type="term" value="F:3-hydroxyisobutyryl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004300">
        <property type="term" value="F:enoyl-CoA hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045004">
        <property type="entry name" value="ECH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032259">
        <property type="entry name" value="HIBYL-CoA-H"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43176">
        <property type="entry name" value="PTHR43176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16113">
        <property type="entry name" value="ECH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ECH_2" evidence="2">
        <location>
            <begin position="19"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="380" mass="42385" checksum="B17FA1A53054B012" modified="2010-01-19" version="1">MEKGRILVSYIECKTGNKIGVLTLDNPNSLNALNYDMLVAIKAQLQQWESDPEVVCVFIDSVDDNAFCAGGDIREMYRAMADHSDDVTQLLFTQYFTAEYSCDYEVNCCSKPVIAWGHGLVMGGGMGIYMAADYRIVTENSQLAMPEVRIGLYPDVGATYFLSQLPSGVGLFLGLTGCRVNASDALFLGMANAFIRKEQKEQFIATLQQISWRSDITQEAQNENHQHIESQLSILSEENAAVYPASQMVPYLPQIQAACHHGDLNIVAEQILAIDGLGPWLEEAKQGLRDGSPISAHICFRQLTQYNHISLAESYRLDLGLSIRCGLLGEFQEGVRAKLIDKDQCPNWRYKSLKEVDSSLIDTLFEPLWLADDHPFSSFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2Q5</accession>
    <name>D0Z2Q5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000706</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305112.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000706"/>
    <dbReference type="EnsemblBacteria" id="EEZ39686">
        <property type="protein sequence ID" value="EEZ39686"/>
        <property type="gene ID" value="VDA_000706"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3416">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1764423at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018648">
        <property type="entry name" value="DUF2076"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09849">
        <property type="entry name" value="DUF2076"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="208"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="266" mass="28251" checksum="18391853F2D3BF85" modified="2010-01-19" version="1">MTPQEKELILSVANKLKQSPNNKKDSEAETVINTEIASQPDAIYKLTQAVLVQEMALKNLKEQNEYLQKNSEYYKEQNNRGTFSRMFGGSQAAPQPPQPPVRQPSAFGGFMQTAAGVAAGMVAGHLISDMLFDNKDTATPEETVVVDDNNQNTAPDNADAAQQDTAQNSDTSSNDNDFENPAFDDNSNGGSFLDDTANNSFSGGFGDSGFSDSSFGSDTGFGGDNGFTDNSGFGDDDTFANNGFGGGDDSFFGGDDSGFGDDDDTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2S9</accession>
    <name>D0Z2S9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Amino acid ABC transporter permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_000730</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000730"/>
    <dbReference type="EnsemblBacteria" id="EEZ39710">
        <property type="protein sequence ID" value="EEZ39710"/>
        <property type="gene ID" value="VDA_000730"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0765">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1523519at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010065">
        <property type="entry name" value="AA_ABC_transptr_permease_3TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043429">
        <property type="entry name" value="ArtM/GltK/GlnP/TcyL/YhdX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30614">
        <property type="entry name" value="PTHR30614"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01726">
        <property type="entry name" value="HEQRo_perm_3TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="80"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="125"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="248"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="8">
        <location>
            <begin position="80"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ39710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="280" mass="31144" checksum="803883A9BDD099A9" modified="2010-01-19" version="1">MTHSNSSLQKSVSNKLNWWQICKPAFSALVQIGLVIAVLGWILSSGADAMNYRWQWHQIPQYLFVHEDGEWYRGELIDGLLITLKISAVSLIFTLGLGLITALLRLSDSIVGRALARGYIELIRNTPLLVQIYILYFVLGPILDLERFTTAVLALSLFQGAYTAEIFRAGLNAIPKGQFEAAASLGLSQWQMYRFVILPQVIKRILPPLTNETVSLVKNSSIVSIMAIFDLTTEGRNIVADTAMPFEVWFTVAAIYLCVTLLLSAVAAWMAHRLNTAIAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2Z8</accession>
    <name>D0Z2Z8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cytosine deaminase</fullName>
            <ecNumber evidence="2">3.5.4.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000799</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.5.4.1" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000799"/>
    <dbReference type="EnsemblBacteria" id="EEZ39779">
        <property type="protein sequence ID" value="EEZ39779"/>
        <property type="gene ID" value="VDA_000799"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0402">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102480">
        <property type="term" value="F:5-fluorocytosine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004131">
        <property type="term" value="F:cytosine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013108">
        <property type="entry name" value="Amidohydro_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07969">
        <property type="entry name" value="Amidohydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro_3" evidence="1">
        <location>
            <begin position="47"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="430" mass="48493" checksum="B3925BB08F1017CE" modified="2010-01-19" version="1">MMHSSNMLITNVTLQGKEGLYQILIHDGKFTAIEPMAAALSYPENTQVIDGEKGMAMAPFCEPHIHLDTTQTAGEPNWNISGTLFEGIERWAERKALLSIEDVKSRAKQTLKWQIANGIQHVRTHVDVSDPTLTALKAMIEVREEMRPWVDIQIVAFPQEGILSYPNGKELLEQAVELGADVIGAIPHFEFTREYGIESLHYVFELARKYNRLIDVHCDEIDDEQSRFVETVAALAHKYEMGHKVTASHTTAMHSYNGAYASRLFRLLKMSGISFVANPLVNIHLQGRFDDYPKRRGITRVKEMLGADINVCFGHDDVFDPWYPLGTANMLQVLHMGLHVCQIMGYEQINQSLNLISTHSAKTLNIQDHYGINLGKPGNLLVLPAENGFDAVRRQVPVRYSIRSGRIIAQTQPAKTEICLDKTENISFKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z361</accession>
    <name>D0Z361_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cyclopropane-fatty-acyl-phospholipid synthase</fullName>
            <ecNumber evidence="3">2.1.1.79</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000862</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CFA/CMAS family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.79" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305559.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000862"/>
    <dbReference type="EnsemblBacteria" id="EEZ39842">
        <property type="protein sequence ID" value="EEZ39842"/>
        <property type="gene ID" value="VDA_000862"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2230">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1518440at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008825">
        <property type="term" value="F:cyclopropane-fatty-acyl-phospholipid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003333">
        <property type="entry name" value="Mycolic_cyclopropane_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003085">
        <property type="entry name" value="CMAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="active site" evidence="2">
        <location>
            <position position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR003085-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="383" mass="43724" checksum="5218F238121EF444" modified="2010-01-19" version="1">MTNEQFFQQILDYADVKINGDRPWDIQILDDAVYDRVLEHGSLGFGESYMDGLWTCDAIDEMISRVLHAHIEEKLGIATKLKVGFKAGKAKLKHLFNAQSIERSSQDVPFHYDLGNDLFEAMLDKRMTYTCAYWQGKHGAEYLDEAQEAKLDLVCRKMGLEPGMRVLDIGCGWGSFMTYAAEKYGVICDGLTLSKEQAALGQQRANNKNLPVNFILQDYRLYTTEQPYDRIVSIGMMEHVGPDNYHDYFKAAFSLLKEDGIFLLHTIGSPESKSEADAWIHKYIFPNGVIPSMCQIGAAAEDYFNIEDVHNIGPDYDTTLMAWCEKFEQAWPTLADKYGEKFHRMWRYYLLSCAGAFRCRDLNVWQFGLTKKGAELPHSVRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3G5</accession>
    <name>D0Z3G5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">OMP_b-brl domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000966</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305856.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000966"/>
    <dbReference type="EnsemblBacteria" id="EEZ39946">
        <property type="protein sequence ID" value="EEZ39946"/>
        <property type="gene ID" value="VDA_000966"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3637">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2059638at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027385">
        <property type="entry name" value="OMP_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13505">
        <property type="entry name" value="OMP_b-brl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019373" description="OMP_b-brl domain-containing protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="OMP_b-brl" evidence="2">
        <location>
            <begin position="12"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="190" mass="21204" checksum="6FD528016C929A0F" modified="2010-01-19" version="1">MSNLFRLYIISSLFTASAATWAATPSNVIGLNLGYGGLNASTKLKDFDSSDLFDGDLYYRRMFNENFGLEVGYRSSTGGLGSMLISPLTKITDISYYGPHSDLYANYPLTGGFSLYGKVGINYYKLDYTYQTNIEGKKQQHRITDSELGGEVAAGVEWRYKWLGFNFGYMYSKSDLIETSGVQFGTSIHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3N5</accession>
    <name>D0Z3N5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001036</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306045.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001036"/>
    <dbReference type="EnsemblBacteria" id="EEZ40016">
        <property type="protein sequence ID" value="EEZ40016"/>
        <property type="gene ID" value="VDA_001036"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1566">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="757027at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043602">
        <property type="entry name" value="CusB_dom_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00529">
        <property type="entry name" value="CusB_dom_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HlyD_D23" evidence="4">
        <location>
            <begin position="40"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="CusB_dom_1" evidence="3">
        <location>
            <begin position="229"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="78"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="302" mass="33409" checksum="F0B224C027801CC7" modified="2010-01-19" version="1">MFKRLLITSCFVIIALMTIGWKYQQYLMNPWTRDGLVRAQIVQITPRVTGPIIHLNIKDNSEVKAGQVLFTIDPRTYKTALEKAKGNLDQAKAQLQRAKDEASRGRQLALRQPGAISKITLVQQKNTVTAAKAGVEAAKALYDQSKLDLSFTKVTAPVDGYITNLNLNVGSQVVANQPVVALIDKHSFWIDGFFKETDISDVTTGDKATVTLMAYGDQPLSGNVESIGYGIAHKDGSTGNSLLPNVNPTFQWIRLAQRIPVRIRLDHVPQDIQFRIGSSASIVIHKKHLAQNALLQRIEEVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3X1</accession>
    <name>D0Z3X1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001124</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001124"/>
    <dbReference type="EnsemblBacteria" id="EEZ40102">
        <property type="protein sequence ID" value="EEZ40102"/>
        <property type="gene ID" value="VDA_001124"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2990">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="736338at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007488">
        <property type="entry name" value="DUF535"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38785">
        <property type="entry name" value="PTHR38785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04393">
        <property type="entry name" value="DUF535"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="311" mass="36286" checksum="222D3E30B0345594" modified="2010-01-19" version="1">MSTTLPSQDNNSRLQQAISLANLVYPHTAGIQKIRKNARFVFWCLTSPKTVQTMLDLLTTPLLAPLKTQFPCLLEKPLKPYGNLGWSQARRTQLIVEHFTFMLKHFPYHIDAIYKNRGIVLYQFQDKDKRSYSINLNSGERREGSLGLQLIDEYGQRLYSISFTISTTENTLYIGSLQGPTESIYNRNETIKSLTKALHGLRTKALMVEIVMMFAQLFEIENICAISNQGHIYQALRYIGSKRNAVSFDYDKLWQEYHGKRIDKYTYQLPTQPERKDVDQLNRTKRKLYTKRYQWLDECKIALANSIMLYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3Y8</accession>
    <name>D0Z3Y8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pyridoxine/pyridoxamine 5'-phosphate oxidase</fullName>
            <ecNumber evidence="5">1.4.3.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">PNP/PMP oxidase</fullName>
            <shortName evidence="5">PNPOx</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Pyridoxal 5'-phosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">pdxH</name>
        <name evidence="10" type="ORF">VDA_001141</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>H2O + O2 + pyridoxamine 5'-phosphate = H2O2 + NH4(+) + pyridoxal 5'-phosphate</text>
            <dbReference type="Rhea" id="RHEA:15817"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:58451"/>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
            <dbReference type="EC" id="1.4.3.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>O2 + pyridoxine 5'-phosphate = H2O2 + pyridoxal 5'-phosphate</text>
            <dbReference type="Rhea" id="RHEA:15149"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:58589"/>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
            <dbReference type="EC" id="1.4.3.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5 7">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
        <text evidence="5 7">Binds 1 FMN per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor metabolism; pyridoxal 5'-phosphate salvage; pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor metabolism; pyridoxal 5'-phosphate salvage; pyridoxal 5'-phosphate from pyridoxine 5'-phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the pyridoxamine 5'-phosphate oxidase family.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.5" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306324.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001141"/>
    <dbReference type="EnsemblBacteria" id="EEZ40119">
        <property type="protein sequence ID" value="EEZ40119"/>
        <property type="gene ID" value="VDA_001141"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0259">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1542844at2"/>
    <dbReference type="UniPathway" id="UPA01068">
        <property type="reaction ID" value="UER00304"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004733">
        <property type="term" value="F:pyridoxamine-phosphate oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008615">
        <property type="term" value="P:pyridoxine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01629">
        <property type="entry name" value="PdxH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000659">
        <property type="entry name" value="Pyridox_Oxase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019740">
        <property type="entry name" value="Pyridox_Oxase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011576">
        <property type="entry name" value="Pyridox_Oxase_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019576">
        <property type="entry name" value="Pyridoxamine_oxidase_dimer_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10851">
        <property type="entry name" value="PTHR10851"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10590">
        <property type="entry name" value="PNP_phzG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01243">
        <property type="entry name" value="Putative_PNPOx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000190">
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="5" id="KW-0664">Pyridoxine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Putative_PNPOx" evidence="8">
        <location>
            <begin position="33"/>
            <end position="116"/>
        </location>
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    <feature type="domain" description="PNP_phzG_C" evidence="9">
        <location>
            <begin position="171"/>
            <end position="212"/>
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        <location>
            <begin position="7"/>
            <end position="10"/>
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            <begin position="190"/>
            <end position="192"/>
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        <location>
            <begin position="60"/>
            <end position="65"/>
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        <ligand>
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        </ligand>
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        <location>
            <position position="65"/>
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            <name>substrate</name>
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        <location>
            <begin position="75"/>
            <end position="76"/>
        </location>
        <ligand>
            <name>FMN</name>
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        </ligand>
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        <location>
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        <ligand>
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        </ligand>
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        <location>
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            <name>FMN</name>
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        </ligand>
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        <location>
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        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
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        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>substrate</name>
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        <location>
            <position position="126"/>
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        <ligand>
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            <position position="130"/>
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        <ligand>
            <name>substrate</name>
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        <location>
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        </location>
        <ligand>
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        <ligand>
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        <location>
            <position position="194"/>
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        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
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        <source>
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        <source>
            <dbReference type="HAMAP-Rule" id="MF_01629"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="PIRSR" id="PIRSR000190-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF10590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ40119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="212" mass="24549" checksum="238D1CA382660830" modified="2010-01-19" version="1">MDLSDIRRDYTKGGLRREDLTQNPLDLFNIWLQQAIDAQLSDPTAMTVATVDSEGRPYQRIVLLKDVGDDGFVFYTNLGSRKALHLQDNANISLHFPWHSLERQIHVTGTAEKLSSFEVVKYFSSRPKESQIAAWASKQSSRLSTRQLLESKYFELKKKFSEGDVPLPSFWGGYRVRISSIEFWQGGDHRLHDRFLYTKVDHENWSIERLAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z417</accession>
    <name>D0Z417_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hypothetical membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
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                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EEZ40148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001170"/>
    <dbReference type="EnsemblBacteria" id="EEZ40148">
        <property type="protein sequence ID" value="EEZ40148"/>
        <property type="gene ID" value="VDA_001170"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3619">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1396398at2"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="DUF1275"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06912">
        <property type="entry name" value="DUF1275"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
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    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="163"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="189"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="216" mass="23656" checksum="8C0030AFC43F94CF" modified="2010-01-19" version="1">MLKKQLLTLMPFYLLFIAGIVDVIGFLHLKNGLFVSFMSGNTTHVGILLNEPSNPLIWHYVGVIGLFVFGAMIGEMLALSAFRYYRCIIMAIVALLLSITALITNHTAPIVTNFVLSFAMGIQNIALRATIDKATALTYVTGFLVNTGRSLALLLMGHREQSAFFRHLLLWLSIFLGAITGAKVMTGSLTIALITPIVLSLIATVILYWTHELADA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z424</accession>
    <name>D0Z424_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Formate dehydrogenase H</fullName>
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        </submittedName>
    </protein>
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        <name evidence="9" type="ORF">VDA_000280</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
            <dbReference type="ChEBI" id="CHEBI:60539"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="1.2.1.2" evidence="9"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="term" value="F:formate dehydrogenase (NAD+) activity"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:molybdopterin cofactor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015942">
        <property type="term" value="P:formate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02790">
        <property type="entry name" value="MopB_CT_Formate-Dh_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02753">
        <property type="entry name" value="MopB_Formate-Dh-H"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041925">
        <property type="entry name" value="CT_Formate-Dh_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041924">
        <property type="entry name" value="Formate_Dh-H_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006478">
        <property type="entry name" value="Formate_DH_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006657">
        <property type="entry name" value="MoPterin_dinucl-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006656">
        <property type="entry name" value="Mopterin_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006963">
        <property type="entry name" value="Mopterin_OxRdtase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04879">
        <property type="entry name" value="Molybdop_Fe4S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00384">
        <property type="entry name" value="Molybdopterin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01568">
        <property type="entry name" value="Molydop_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00926">
        <property type="entry name" value="Molybdop_Fe4S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="SSF50692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01591">
        <property type="entry name" value="Fdh-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51669">
        <property type="entry name" value="4FE4S_MOW_BIS_MGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5 7" id="KW-0408">Iron</keyword>
    <keyword evidence="6 7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0574">Periplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0711">Selenium</keyword>
    <keyword evidence="9" id="KW-0712">Selenocysteine</keyword>
    <feature type="domain" description="4Fe-4S Mo/W bis-MGD-type" evidence="8">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="11"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="42"/>
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        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="non-standard amino acid" description="Selenocysteine" evidence="9">
        <location>
            <position position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ39262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="714" mass="79211" checksum="B5431CE98938075A" modified="2010-01-19" version="1">MKKSIVVCPYCGTGCKLKLVVENNKVIAAEPADGRTNEGQLCLKGYYGWDFLNDTNLLTPRLKQPMTRRTRDAQLEGVSWQEAIDFASEKLLEIKKKYGPEAIMTTGSARGPGNEANYVMQKFARAVIGTNNVDHCARVUHAPSVSGLETTVGNGAMSNAIPEIQHTKCLLIFGYNAADSHPVVARHILKARANGAKIIVCDPRKIESARIADQWLALNNGSNMALVNALANVIIEEGLYNKEFVQNHTEGFAEFREIASHYPPESVEQVTGLTAQEIRLAARTYAAAPEAMILWGMGVTQYGQAVDVVRGLAGLALLTGNFGRRGVGCGPVRGQNNVQGTCDMGMLPHQFPGYQDVTDDAVRSKFEQAWGVSLSGTPGYRLTEMGHKVEEGICKAFYIFGEDPAQTEADLAAMRDTMRKMELVIVQDIFMTQTAEFADVIFPATSWGEHEGVYSSADRGFQRFYKAVKPTGDVKPDWEIFSLLATRMGYPMSYNNTEEIWDELRSLCPLYAGVTYDKMADLKSVQWPCPTEDHPGTSYLFEGNQFSTPSGKGIFIGAEWRAPLEQPDAEYPLVLSTVREVGHYSCRSMTGNCAALQTLADEPGYVQMHPDDAKALGIADQQLVWVSSRRGKVISRANYNERVNKGVVYMTYQWWIGACNELTIEHLDPISKTPEFKYCAVKVEHIDDQSWAENYVQTEYSNLKARLRNHVINA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z471</accession>
    <name>D0Z471_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytosol aminopeptidase PepA</fullName>
            <ecNumber evidence="7">3.4.11.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_000327</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M17 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.1" evidence="7"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304057.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000327"/>
    <dbReference type="EnsemblBacteria" id="EEZ39309">
        <property type="protein sequence ID" value="EEZ39309"/>
        <property type="gene ID" value="VDA_000327"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0260">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="356206at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00433">
        <property type="entry name" value="Peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011356">
        <property type="entry name" value="Leucine_aapep/pepB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000819">
        <property type="entry name" value="Peptidase_M17_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11963">
        <property type="entry name" value="PTHR11963"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00883">
        <property type="entry name" value="Peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00481">
        <property type="entry name" value="LAMNOPPTDASE"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CYTOSOL_AP" evidence="6">
        <location>
            <begin position="141"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="457" mass="49921" checksum="9278F62852DC87A1" modified="2010-01-19" version="1">MLILHLHHHEITTNRTSSLLIDLGEQKNIEIDFQAEDYDGTVSKSAYSIADIQDLGCLLGQQLSKSQQLTLYITPLCLQHIEAEYWIKWLSFGLALANYRYQHQPTATISTSITQYQLETSNTRWQQAFNEGKVLALSQLTARELINKPGNVLYPESFVSAVEQLALSGVTLSVLDDITMQEQGFGGLMGVSQGSNKAPRLLTLEYTPANPSCTIALVGKGVTFDSGGISLKQPSYMSTMKTDMAGAAAVVGAIQAISTLQLPVHVIGLCGLVENMPSSQALKPGDVVTMLSGKSVEIITTDAEGRMVLADVLHYAQQQYQPDYLIDIATLTGAAGIALGKAYAAVMGNDEELIKQAQHSGLQCFERLWPLPIDPWYQDILASDYADYRHGGETPDGSPCVAATFLAQFIQPQQKWIHIDCAAMTFQPQRKLYSKASTGFGTLLLTQLCEHIAKDNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-06-02" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z489</accession>
    <name>D0Z489_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000345</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39327">
        <property type="protein sequence ID" value="EEZ39327"/>
        <property type="gene ID" value="VDA_000345"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="48" mass="5491" checksum="6533A21CE1D4D819" modified="2010-01-19" version="1">MFEWLKKLFGDNRTENEIIDQQDTSAEELERQQKYAQGAPSDDGDGGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4E6</accession>
    <name>D0Z4E6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">VgrG protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000402</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the VgrG protein family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304268.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000402"/>
    <dbReference type="EnsemblBacteria" id="EEZ39384">
        <property type="protein sequence ID" value="EEZ39384"/>
        <property type="gene ID" value="VDA_000402"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3501">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1880900at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006531">
        <property type="entry name" value="Gp5/Vgr_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017847">
        <property type="entry name" value="T6SS_RhsGE_Vgr_subset"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006533">
        <property type="entry name" value="T6SS_Vgr_RhsGE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037026">
        <property type="entry name" value="Vgr_OB-fold_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04717">
        <property type="entry name" value="Phage_base_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01646">
        <property type="entry name" value="vgr_GE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03361">
        <property type="entry name" value="VI_Rhs_Vgr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phage_base_V" evidence="2">
        <location>
            <begin position="384"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="679" mass="75440" checksum="F33EE81DA84C8A28" modified="2010-01-19" version="1">MASGLQFTFTVEGLDASTFAVTEFRGSDGLSLPFSFSIDLASRNPSLSPNDTVDRNCCLSVWREGELKQQWFGIVAGFSQGDTGHHHTLYQVQMIPPIGRLALRHNSRIFQTQTVPEIISILLQEMNVQDYAFALARQYPQREYCVQYRETDLAFLQRIAAEEGIFFSFSHKGNKNTVIFTDDTQNVAMLPEPVAYNGLSGGSSPLPFVRQFKRMAQIRPSSAQLKDYSFKNPAYSFLLTEQAKEAAYQQAIYEQYDYPGRYKNDESGKPFTQFRLESLRRDAETAQAKSNLEILLAGSKFVLQDHSDDACNRDWLLVEIKHHGTQPQALEEAGGHGVTTYNNEFVVIPGHKPWRPPFNAKPCVDGPQIARVVGPEGEEIYCDEFGRVKIQFPWDRYSNNDDNASCWVRVSQGWAGTQYGMVALPRVGHEVIVDFFEGDPDQPIITGRTYNATNKPPYELPAHKTRTVLRTETHQGDGYNELRFEDQAGKEEIYVHAQKDMNLLVENDRKDDIKHDLHLDVANERFTHIKANDHLTVDGESRSHTKGNKTIVTDASSHLKQGNSLLVDAGREIHLKGGSKIVVESDAELTLKAGGSFVKIDGSGVSIVGSKINLNSGGSAGSGSGYAGSAPLLPGGVEPAKTITEVQSSNIAPTKEAQNALLKESDNQDDFLSKFRFSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4L6</accession>
    <name>D0Z4L6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glucose transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_000474</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304463.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000474"/>
    <dbReference type="EnsemblBacteria" id="EEZ39454">
        <property type="protein sequence ID" value="EEZ39454"/>
        <property type="gene ID" value="VDA_000474"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1121832at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="41"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="108"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="165"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="197"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="289"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="331"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="364"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="387"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="427"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="452"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="41"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="488" mass="54137" checksum="B5B9C58B4DBEEEB9" modified="2010-01-19" version="1">MNQEIEIQSQKTIQTYIDDISSWHEESKISYMSMTKVQWRIWLLATFGKFFEGMIVFMMGLTLPLITLQFQLTEFQKGTISSSILFGILIGASALGGLSDLYGRKKMFIIEMALLSVCLVGMAFSQSYWCVLLFNFGIGLALGCDYPTAHLMISESIPTKNRGKLVLGAFAFQSVGVLMGILTGIVVLSYVEDVNAWRVMYVLALVPSLAITIARFFIPESAHWLLSKNRKQDAERCLKRLLNRDQACDMALRSEPVQDEVEVQSWLHGYKKLFKEKYRAKTILASAPWFIQDLGTYGIGIFTPVILASVLEHQTIAGADELHNTIANIIYSAKGTALIDSLLIVGVICAIIFSESIGRMKLQIYGFVGCAVGLLLAAVSVKVHSDYQIYVLFLGFMLFNFMNNLGPNAQTYLISGEVFPVKIRAKGAGFAASIAKLGAILTAFMFPILLHVIGVFSLLLTLVVTSLLGAWVTHKYRFETSGKNIENL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4M0</accession>
    <name>D0Z4M0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000478</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304475.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39458">
        <property type="protein sequence ID" value="EEZ39458"/>
        <property type="gene ID" value="VDA_000478"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031NIX">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2123140at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="252" mass="28814" checksum="F7E9A203ED34EBFF" modified="2010-01-19" version="1">MSTRLNETISLELQIQSAVREMIAFTELSSKSSTYQDRLQGAIHHTKILLTLSLMTRAFFSEAQNTANKLLNIEQRFYDFEYVIQRSITSYTLSCRDPSLQQAIAHNKASMVNEAEILNYLSQPLSLDVENMIAALATKHVKTLALEFSLHEDIDNQIDEAFCHTLTSLWLDLGFCLSEDATCRLLEQIIHSRTGTMCLLFLNMTEHHREREAVRLYFAEIDKFYAALTASGLKRGIKFLNHITKNPDSDDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4U3</accession>
    <name>D0Z4U3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Magnesium transporting ATPase P-type 1</fullName>
            <ecNumber evidence="7">3.6.3.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_000176</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.6.3.2" evidence="7"/>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000176"/>
    <dbReference type="EnsemblBacteria" id="EEZ39160">
        <property type="protein sequence ID" value="EEZ39160"/>
        <property type="gene ID" value="VDA_000176"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0474">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015444">
        <property type="term" value="F:P-type magnesium transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02077">
        <property type="entry name" value="P-type_ATPase_Mg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006415">
        <property type="entry name" value="P-type_ATPase_IIIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01836">
        <property type="entry name" value="MGATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="SSF81660"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01524">
        <property type="entry name" value="ATPase-IIIB_Mg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-1278">Translocase</keyword>
    <keyword evidence="1 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="77"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="471"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="529"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="594"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="626"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="domain" description="Cation_ATPase_C" evidence="6">
        <location>
            <begin position="483"/>
            <end position="651"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="660" mass="72759" checksum="62BDEB77BD035FAE" modified="2010-01-19" version="1">MGTNVTSGRAQAVVVATGNRTWFGSLAKSIVGTRTQTAFDRGVNSVSWLLIRFMLVMVPIVLLINGFSKGDWVEASLFALAVAVGLTPEMLPMIVSSNLAKGAIAMSRRKVIVKRLNAIQNFGAMDVLCTDKTGTLTQDNIILEHHLDVSGHESDRVLTLAWLNSSSQSGARNLMDRAVLRFGEGRIAPATKERFVKLDELPFDFVRRRVSVSVEDVRHGDKSLICKGAVEEMLMVATHLREGDNVVALDETRRDLLLAKTKDYNAQGFRVLLVATRKLDDSALTTPLCTADEQGLTVEGMLTFLDPPKESAGKAITALRDNGVAVKVLTGDNPVVTARICLEVGIDAHGILTGAQIEAMTDRELEREVETRSVFAKLTPLQKSRILKTLQKNGHTVGFLGDGINDAPALRDADVGISVDSAADIAKEASDIILLEKDLMVLEEGVIKGRETFGNIIKYLNMTASSNFGNVFSVLVASAFIPFLPMLAIHLLIQNLMYDLSQLSLPWDKMDKEFLRKPRKWDAKNIGRFMLWIGPTSSIFDITTFALMWYVFAANNVEAQALFQSGWFIEGLLSQTLVVHMLRTQKIPFIQSRATLPVLLTTAVIMAMGIYIPFSPLGAMVGLEPLPLSYFPWLVATLLSYCLVAQGMKRFYIKRFGQWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4V6</accession>
    <name>D0Z4V6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000189</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306556.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39173">
        <property type="protein sequence ID" value="EEZ39173"/>
        <property type="gene ID" value="VDA_000189"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031TS8">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="737929at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031835">
        <property type="entry name" value="ExsD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16806">
        <property type="entry name" value="ExsD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="325" mass="37898" checksum="414771CC98324639" modified="2010-01-19" version="1">MKKLHWRRRSRYPNNIVTQRKVTVLQRGVRYEGLTQSSQVPNVVNINHRQLLSEEVLSSEQLSLLLRLLDRNVVDCLCASQVVKTYQRFGTSLDRFAMRLFLEVGGQLSNNHVLSSFEQRLDYINCQLGFRFNLASPKTLILSMYLTLNEWVNRKTDQTVLHDTIQLEQLINQLSIQKDYWLRLSTEENSAIFAKQQLALNQSQQSELPDFVVLNEQQNQAVESHQAMVEEWKPTLDKLKGLSQYGETSDKFISEWKVWCGEARVQAPELNDVWDACDHVYSDLNAVAKIWQWFQDMHTVGNVDHYYFDIQSNQCGQVCNHLSQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z534</accession>
    <name>D0Z534_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">IncF plasmid conjugative transfer protein TraD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000267</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306780.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000267"/>
    <dbReference type="EnsemblBacteria" id="EEZ39251">
        <property type="protein sequence ID" value="EEZ39251"/>
        <property type="gene ID" value="VDA_000267"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3505">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="246216at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014128">
        <property type="entry name" value="T4SS_TraD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019476">
        <property type="entry name" value="T4SS_TraD_DNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10412">
        <property type="entry name" value="TrwB_AAD_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02759">
        <property type="entry name" value="TraD_Ftype"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="112"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="TrwB_AAD_bind" evidence="3">
        <location>
            <begin position="182"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="648"/>
            <end position="667"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="704" mass="80903" checksum="D1F9994948B03534" modified="2010-01-19" version="1">MLSKHRKRPKSDSQAFTRGGQIFFHNWRMYFQIIKRIASWGLWVSLIFTIAYCFLFISANDWAVIQAYFHAKMVSMNPGATIMLTHDGRQFEYVAKELLAKPKFMNDVHSTFRTISLAFAFSFVAMIVFLSLLSRYFTSKGKEQTQDYLVRGVEIATPKELEKRIKQQKKPSTFKIDGLQILPNDFEIRHLSFSGSTGTGKSVAIRKLIREIRARGDKAIIYDKGCTFVSRFYDPKLDTILNPFDERSVDWKIWYDGKEFSDFENLATALIADTGHGDPFWIEAARTIFTNTAYQMTQDGKELSNERLLDYILKTPTSVLRDFLKGTSASSITDEKADKIAVSVKSILATYIKSLRYLEGLDKPDKDGKARKAFSVQDWVLDDNEKGFLFLTSNAQQHVSLRPLISMWLSTASTAILGLNESASRRIWVIIDELPSLHKLPDLASTLAEVRKHGGCYLVGFQSYAQFVKVYGQHAADEMYDLLNTRFYFRNPSSPMAERASKDLGEQEVEISKEQYSYGANTVRDGISLGHQTITRPAVMPSEIMALDDLQCWYRTFGGFPITRLNLAYDDMKAVAHSFIKREYESSKTMRRLDGEIAHYQIGALLALPDEDKKALLRIHRAQHEDQESFDNERERMKEDAQELREKLEEGKETKTHNNDQELDAQKLKEDKAMKRQLETIDQTEQALRETEETMINNDMMPFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z544</accession>
    <name>D0Z544_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000094</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306826.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000004.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39078">
        <property type="protein sequence ID" value="EEZ39078"/>
        <property type="gene ID" value="VDA_000094"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502ZXMA">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2173716at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="335"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="359" mass="42472" checksum="75BCBD77AA407FFE" modified="2010-01-19" version="1">MEIRAFAYSIDYNNYITTNDGKLKIFYIKEVVNELLRRPDAFDHIDFMSTNPDQEARIKLIPKKIHGVDQFVRIEHDNMVIPQKNETKYGIVEALSRIIVMTLETNKETFKFNLESIRKGSKLLFCNKKIYYPDLICTFPETHELYEKWGGRFIILINYHNHYKPDMLSDYESYNIPVFVIDIDIDSDKIFPQERSNIESYTQEDVDIYIDRLYSHFVKKINSRLLIDPSSTKYSKYIIKTKEDEIKDKDNIIFGLNQRITSADNKLLKLKEIENELNTTVDLAMDLKGKLSFIEADNLRYIDINRQLSLEKDVQKRKIASLHQKYNDCESKLDLFRLISISLIIFVFLLIILLVLYII</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z597</accession>
    <name>D0Z597_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000147</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306981.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000004.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39131">
        <property type="protein sequence ID" value="EEZ39131"/>
        <property type="gene ID" value="VDA_000147"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5032X16">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1982171at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037883">
        <property type="entry name" value="Knr4/Smi1-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160631">
        <property type="entry name" value="SSF160631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="212" mass="23536" checksum="E3D26DE327B6401A" modified="2010-01-19" version="1">MGSYIDKLVLISSDQLSQRKVAPPLEILELAGELGNELEDLLNVKNGFFAFESALRVFPSLTSESSIGLVDWNANSLWRKDYSGFTDGALFFAEDIFGGQFCIKNNVICSFDPETGSFEEMASNFESWVQEILSDYNVWTGYSLAHEWQEAYGSLPNDMRLMPKVPFVCGGAFELDNLSAIKAVSGMRTRANLACQIANLPDGAQIEFKIIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-06-02" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5D9</accession>
    <name>D0Z5D9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">IncF plasmid conjugative transfer protein TraG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000046</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000005">
        <property type="protein sequence ID" value="EEZ39061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005307071.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000005.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000046"/>
    <dbReference type="EnsemblBacteria" id="EEZ39061">
        <property type="protein sequence ID" value="EEZ39061"/>
        <property type="gene ID" value="VDA_000046"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="29010at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012931">
        <property type="entry name" value="TraG_N_Proteobacteria"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07916">
        <property type="entry name" value="TraG_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="326"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="362"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="416"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="domain" description="TraG_N" evidence="3">
        <location>
            <begin position="7"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="544"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="654"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="842"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="675"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="853"/>
            <end position="867"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="903" mass="98944" checksum="D8EB48D16D053487" modified="2010-01-19" version="1">MANVYDVYVFSGGATAEKVFNAIATFLRGDSYGHLLAIVGMCALLMTMFRFFTSRDHTHLLSYIAVNLTVSSMLLIPTATVRIDDSSMSGRTYFVDNVPIGVAAPIHYATTFMYGLARATDVIFVQPDEAAYTKSGMLFGSKLVGLSQRIGIQDGELKQLWGQYTQNCIRKDITINKKYTWTQFAQAGDIFEFLKNNRPSPVRRIAMNGAFPTCQEALPLLENKFRDEANKSFRLMSTETVINGWATNEALLQNAVASSYRTFHNINKSASDLLKQNIAVNGVKSGLLDSAASTGATAAAFNYAATHSQMQTQSFMTSMGINAAEWLPIVNSVLILLLACSSIPVFLAAFIPGMTVRVLKGYLGGFFYLALWPFFFTVINLIMTYSLQYAGAESTNLLHGMSLAGSSPLQAMHYKYAAIAGWLMMMVPIISKYALTGGLVMAGSLGQQFLGAMGSNAARSSQAAASGDMTYGVVQTDTWHSNSMSGNKVDTAYSNQSYGAQVQRADGSSVNYLPGGNAVYSSRGAISTTGFDINSSEVQSRALQNSYTEAQRATSQARTAYSQSSGSVTDQLMSLSSSASRNTSYGEGTQYSSNSSTQNSLSKLDGVVAEEAKAKGVSKEEAYKQMVDNYLDYNASGSASLGAGVGEFGNIKGGANISKGRRYSDTESSTDSQRQDRTSRTSNSRQNQFNDLMSSIEQYGTSGRTEDLHGFNQQAMSTLSEAIKESKDLAKTVDSSIAKEQAYSAALQDSQTGSLSVNTNLMPEFQAYVARRRPENVEAIMNGNTPAINEERDLFFQAFMSERFSNYNPELKQAWDDSSMNRPAQSVQGRDIQSNYERNSGSIENQYQTEQGHRQKQFDEESEQSQRALYDNDAYLHNKQEQENARQLTEQELKEIKEYRGMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVI5</accession>
    <name>D0YVI5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">O-succinylbenzoic acid--CoA ligase</fullName>
            <ecNumber evidence="4">6.2.1.26</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001565</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="6.2.1.26" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298288.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001565"/>
    <dbReference type="EnsemblBacteria" id="EEZ40539">
        <property type="protein sequence ID" value="EEZ40539"/>
        <property type="gene ID" value="VDA_001565"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0318">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="377638at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008756">
        <property type="term" value="F:o-succinylbenzoate-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009234">
        <property type="term" value="P:menaquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010192">
        <property type="entry name" value="MenE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01923">
        <property type="entry name" value="menE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0474">Menaquinone biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="2">
        <location>
            <begin position="15"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="3">
        <location>
            <begin position="385"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="476" mass="53002" checksum="14B2C9CBF93A72DA" modified="2010-01-19" version="1">MPEINHDFVTWPWQYWATERGDDIALRLGGDQQQANMTWSQVSHYIDLYAQSLLAQGVKRDQLVAVIAPNSEQTLWMLLAIWRVGARYVGLNPKLTKAEVSTQLAQLQHDFIWSVDYDLTGLSGQTLTLELAQTQQMIPVMWQAHRAVTLTLTSGSTGTPKAAVHSPESHLANASGLLARFGYLAADTWLLSLPLFHISGMAIIWRWLSQGACLAINDKQPLNEALDSVTHASLVPTQLQRYLDYLGQNQRTAQLKRVLLGGAIIPVTLTQQATSLGIECWCGYGMTEMGSTVTAKLADDSAGVGQVLPNRELFLRDGEILVKGKALCLGYYRNKTIFPVVGNNELEPEWFATKDLGIWHNDELFIQGRVDNMFISGGENVQPEDIEKVLLAHPSVHQAFILPIADDEFGQRPVAILVTSHALDDGLVAQLQSYMAEHVTSFKRPIHYVALPEIFMESGIKISRKQLADWVSHYSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVL6</accession>
    <name>D0YVL6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_001608</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298370.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001608"/>
    <dbReference type="EnsemblBacteria" id="EEZ40581">
        <property type="protein sequence ID" value="EEZ40581"/>
        <property type="gene ID" value="VDA_001608"/>
    </dbReference>
    <dbReference type="GeneID" id="57342314"/>
    <dbReference type="eggNOG" id="COG2056">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1000841at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018461">
        <property type="entry name" value="Na/H_Antiport_NhaC-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032813">
        <property type="entry name" value="Na_H_antiport_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13726">
        <property type="entry name" value="Na_H_antiport_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03553">
        <property type="entry name" value="Na_H_antiporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="58"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="150"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="191"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="235"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="259"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="289"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="332"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="362"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="422"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="domain" description="Na_H_antiport_2" evidence="8">
        <location>
            <begin position="2"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="Na_H_antiporter" evidence="7">
        <location>
            <begin position="150"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ40581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="440" mass="45917" checksum="7F6501AA09983DF4" modified="2010-01-19" version="1">MNPVVIAVCVMLVLALLRVNVVVALTFSAIVGGLIGGLSLTDAVTAFQNGLGGGATTALSYAMLGTFAVAISHSGITDVLAQKVIKRISGHENAAAATGVKYSVLTILLLLAISSQNAIPVHIAFIPIVIPPLLHVFAKLKLDRRLIACVLTFGLVTPYMVLPIGFGGIFLNNILLKNLHDNGLDVAANQVPIAMLLPAMGMVTGLLIAVFFSYRKPREYSEAKILANEPEHKTINMKHVYVAIAAILAALGAQIYSSSMIIGGLVGFMVFTVTGVIKYKETHDVFTKGVHMMAMIGFIMIAAAGFASVMKATGGVESLVNSLEAIIGNNKPLASLLMLVVGLLVTMGIGSSFSTIPILATIYVPLCLSFGFSPMATIAIVGTAAALGDAGSPASDSTLGPTSGLNADGQHEHIWETVVPTFIHYNLPLIAAGWIASMIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVR5</accession>
    <name>D0YVR5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">TerB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002006</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002006"/>
    <dbReference type="EnsemblBacteria" id="EEZ40974">
        <property type="protein sequence ID" value="EEZ40974"/>
        <property type="gene ID" value="VDA_002006"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4103">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3680.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007791">
        <property type="entry name" value="DjlA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029024">
        <property type="entry name" value="TerB-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05099">
        <property type="entry name" value="TerB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158682">
        <property type="entry name" value="SSF158682"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TerB" evidence="1">
        <location>
            <begin position="3"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="125" mass="14241" checksum="6B721AB5AE515561" modified="2010-01-19" version="1">MNLAMASLLCEVANADHAKDPREEQAKVQLLTKLLEVDEQQAQHLLNEGELRSENAVSLYEFTNKLRALEQEARYELVEAMWQVAYADGVIDPMEEAVIRQVAELIYLDHSEFIRAKLSAQKLAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVS2</accession>
    <name>D0YVS2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Hypothetical glycine betaine transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_002013</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299177.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40981">
        <property type="protein sequence ID" value="EEZ40981"/>
        <property type="gene ID" value="VDA_002013"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1292">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1217683at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071705">
        <property type="term" value="P:nitrogen compound transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000060">
        <property type="entry name" value="BCCT_transptr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30047">
        <property type="entry name" value="PTHR30047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02028">
        <property type="entry name" value="BCCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="61"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="150"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="202"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="243"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="274"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="323"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="355"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="414"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="454"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="477"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="517" mass="55015" checksum="D921CD47255C718E" modified="2010-01-19" version="1">MHSTACRAGIKKAPQVDTKLVPILTIGFIALFLIAALVDLSSFTALIQSGFESAANEFGTSWQWLMLINFIIAILVALSPMGKKVMGDQAKPTIGTFRWLAMIMCTLLAGGGVFWSAAEPIYHFITPPPSFGGIEGATQAAVEPALSQAFLHWGFLAWAVLGTLSTIILMYAHHEHGVKLRPRALLFPIFGKRLENHWLGSVIDACSIIAVAAGTIGPIGFLASQLGYSLEVLTGLENNVQSQLVILAIVVAVYSLSAASGMDKGLQWLSRLNVVGAFGLLLAMLLLGPTQFILKEFGYAFGDYLGHISSLSLADSKPAWNVWWTWFFWGWFIGFAPMMAIFIARISEGRSIRGLVFAVAIGAPIATNFWFSVLGGTGIFLELNDPGVISGPLNDAGLPAVLLASLAQLPLSSILLPAFLVLTTTFVVTTGDSMAYSIAMVVSGDNEPSSKHRLFWAITMGCVAAVLLLAGDGGLNALQSFIVITAVPVSILVAFTLVSGPLAAYRMTCAKTAEITA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVV3</accession>
    <name>D0YVV3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 12">Exodeoxyribonuclease I</fullName>
            <ecNumber evidence="2 12">3.1.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">VDA_002034</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates.</text>
            <dbReference type="EC" id="3.1.11.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="14">Binds 2 Mg(2+) ions per monomer.</text>
    </comment>
    <dbReference type="EC" id="3.1.11.1" evidence="2 12"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299234.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002034"/>
    <dbReference type="EnsemblBacteria" id="EEZ41002">
        <property type="protein sequence ID" value="EEZ41002"/>
        <property type="gene ID" value="VDA_002034"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2925">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="768812at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-exoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008852">
        <property type="term" value="F:exodeoxyribonuclease I activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023607">
        <property type="entry name" value="Exodeoxyribonuclease_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034748">
        <property type="entry name" value="EXOI_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034747">
        <property type="entry name" value="EXOI_SH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038649">
        <property type="entry name" value="EXOI_SH3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013620">
        <property type="entry name" value="Exonuc_1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Exonuclease_RNaseT/DNA_pol3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022894">
        <property type="entry name" value="Oligoribonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11046">
        <property type="entry name" value="PTHR11046"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08411">
        <property type="entry name" value="Exonuc_X-T_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000977">
        <property type="entry name" value="Exodeoxyribonuclease_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51785">
        <property type="entry name" value="EXOI_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51784">
        <property type="entry name" value="EXOI_SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 12" id="KW-0227">DNA damage</keyword>
    <keyword evidence="11 12" id="KW-0234">DNA repair</keyword>
    <keyword evidence="10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8 12" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="7 12 17" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 12" id="KW-0540">Nuclease</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ExoI SH3-like" evidence="15">
        <location>
            <begin position="200"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="ExoI C-terminal" evidence="16">
        <location>
            <begin position="357"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="15"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR000977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR000977-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR000977-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EEZ41002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="473" mass="54562" checksum="C6D313BA16A96D43" modified="2010-01-19" version="1">MIKKNEPSLYWIDYETFGASPATDRPCQFAGIRTDMDLNIIGEPLVIYCKPPHDYLPSPEACLITGITPQEANEKGLSEPEFIARIHEELSKPNTCVVGYNNVRFDDEVTRYTLYRNFYDPYGWSWQQGNSRWDLLDIMRTCYALRPDGINWPTDDEGLPSFKLEKLSVANGIEHSNAHDAMADVYATIEMAKLVKQNQPKLFDYLFNNRHKNKLQQLIDVVNLTPLVHVTGMFGTVCGNTSWIVPIAWHPDNKNAVITINLAQDPTPLIELDSETIRTRLYTKRADLAADELPIPLKEVHLNKCPILAPAKTLTANDADRLDIDREQCLKNLALIKQHPEIREKVLEVFSVKREFDNHDNVDAMLYDGFFSHADRVAMDIIRETAPEELANLQLEVADKRIKPLLFRYRARNFPMTLSYEEQTRWKHHCQDYFEANIPRYMENFEQVALDNQSDENKMAILHKLGQYISTLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVZ0</accession>
    <name>D0YVZ0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">GTP pyrophosphokinase (P)ppGpp synthetase I</fullName>
            <ecNumber evidence="6">2.7.6.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_001269</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Purine metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the relA/spoT family.</text>
    </comment>
    <dbReference type="EC" id="2.7.6.5" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297756.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001269"/>
    <dbReference type="EnsemblBacteria" id="EEZ40247">
        <property type="protein sequence ID" value="EEZ40247"/>
        <property type="gene ID" value="VDA_001269"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0317">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="204079at2"/>
    <dbReference type="UniPathway" id="UPA00606"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008728">
        <property type="term" value="F:GTP diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015969">
        <property type="term" value="P:guanosine tetraphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05399">
        <property type="entry name" value="NT_Rel-Spo_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01668">
        <property type="entry name" value="TGS_RSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004811">
        <property type="entry name" value="RelA/Spo_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045600">
        <property type="entry name" value="RelA/SpoT_AH_RIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007685">
        <property type="entry name" value="RelA_SpoT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033655">
        <property type="entry name" value="TGS_RelA/SpoT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13291">
        <property type="entry name" value="ACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19296">
        <property type="entry name" value="DUF5913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04607">
        <property type="entry name" value="RelA_SpoT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02824">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00954">
        <property type="entry name" value="RelA_SpoT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="SSF81271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00691">
        <property type="entry name" value="spoT_relA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HD" evidence="4">
        <location>
            <begin position="54"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="TGS" evidence="5">
        <location>
            <begin position="402"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="domain" description="ACT" evidence="3">
        <location>
            <begin position="665"/>
            <end position="739"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00025704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="739" mass="83976" checksum="896D7CF945EEB9ED" modified="2010-01-19" version="1">MVAVRGAHLKENSKFELAVWVDSLQQEPATAEQIKSTYERCLSLVTEEESAALLLWRGREMVEILVTLSMDADTLVAAMLFPLVEAGLYSHEALTEDYGITISHMVVGVEQMCAISQLKSTTEETAQPGQVDNIRRMLLSMVDDFRCVVIKLAERICHLREVKDEEDAVRRTAAQECANIYAPLANRLGIGQLKWEIEDYAFRYQHPDTYKQIAKQLSERRIDRENYITHFVTDLSEAMKASNIKAEVQGRPKHIYSIWRKMQKKNLAFDELFDVRAVRIIADQLQDCYAALGVVHTKYRHLPKEFDDYVANPKPNGYQSIHTVVLGPEGKTIEIQIRTKQMHEESELGVAAHWKYKEGSSSGAKSAYDEKINWLRKLLAWQEEMSDSGDMLDELRSQVFDDRVYAFTPKGDVVDLPLNATPLDFAYHIHSEVGHRCIGAKVEGRIVPFTYHLQMGDQVEIITQKEPNPSRDWLNPNLGFVNSSRARAKVHAWFRKQDRDKNIIAGREILEQELAKIGATLKDAEAYAIKRFNVKTPDELFAGIGSGDVRINQVINHINALVNKPTAEEEDQQLLEKLTEVKARTAKKPQRDAVVVEGVDNLMTHLARCCQPIPGDDIQGFVTQGRGISVHRSDCEQLDELRHHAPERIIDTVWGGGYAGNYTITVRVTASERNGLIKDLTNTFSNEKVKVSGMKSRIDFKKQMSIMDFELELTDLEVLGRVLKRIEQVKDVAEAKRLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW10</accession>
    <name>D0YW10_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Carbon starvation protein A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">VDA_001315</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297851.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001315"/>
    <dbReference type="EnsemblBacteria" id="EEZ40290">
        <property type="protein sequence ID" value="EEZ40290"/>
        <property type="gene ID" value="VDA_001315"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1966">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="457782at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009267">
        <property type="term" value="P:cellular response to starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025299">
        <property type="entry name" value="CstA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003706">
        <property type="entry name" value="CstA_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02554">
        <property type="entry name" value="CstA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13722">
        <property type="entry name" value="CstA_5TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="80"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="126"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="162"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="190"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="235"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="273"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="317"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="370"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="397"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="422"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="447"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="domain" description="CstA" evidence="9">
        <location>
            <begin position="5"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="CstA_5TM" evidence="10">
        <location>
            <begin position="327"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ40290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="492" mass="53291" checksum="494B53F596E017F5" modified="2010-01-19" version="1">MTWFLFCVAALIGGYFIYGTFIEKIFGINEKRQTPAFTKQDGVDYVPMSNKRVYLVQLLNIAGVGPIFGPIMGALYGPAAMLWIVLGCIFAGAVHDYFSGMLSIRNGGASVPTITGRYLGNGAKHFMNIFAIVLLLLVGVVFVSAPAGMITNLINEQTSFNVTMTSMVVVIFAYYVLATIVPIDTIIGRFYPLFGALLIFMSVGLITAIAFSSEHTLLGNFEVSQMFSNLNPNDMPLWPALFITIACGAISGFHATQSPLMARCLENEKNGRFVFYGAMIGEGIIALIWCAIALSFFGSLEELSNAVSNGGPGNVVYSASFGLLGVFGGVIAFLGVVILPITSGDTAFRSSRLILAEYFNMEQKTLRNRLLIATPLFVLGGILTQVDFGIIWRYFGFANQATAVMMLWTASAYLLRHNKLHWITTVPALFMTTVCITFILNNHQLGFGLPMGISTGLGVAGAIGAMFMVIKRAKASANTDDAKEEQESFETV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW31</accession>
    <name>D0YW31_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Protein containing phage integrase family domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001294</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001294"/>
    <dbReference type="EnsemblBacteria" id="EEZ40269">
        <property type="protein sequence ID" value="EEZ40269"/>
        <property type="gene ID" value="VDA_001294"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0582">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="478" mass="55012" checksum="70AC36BDDB1CAEF8" modified="2010-01-19" version="1">MEKFGISKVRVSSFTRHLISEKLSELFPELSLVITGKTIQKVKEFPNSCPMTFTGKETTVSNNTFDSLTKAPNLLKRYSHYLPELCHYCNPTVTVTESFANTYIRPKERTPNIPTQTALYYLNEAIRIVTVYGEDIVETKKICEYQLNRIHAENPKYRRDYIFESRCPHKIIIPENKFTRDFKVTRYNDLPTGSTPKELRTNVTVLFGYKMLLAATYILAHTFCIKRVSEILELKESSLEHSLWGGYELSFGIRKAAPTDNSILVTGRPIPHVLFEGISCLTEANYHYYAEHEDPFIFPSKCTSTGKGEYPKNQKMSRVAIVGALQSFADFIQVPTEIINGVESRFYLTRTHVLRRFAARAFYALSDLSDFPALSWLMGHRDTEETWHYLLEEVGNEHLSEEEAQCVLDAIYKSNVDTCQVEDTIKSKLNIRFNNQSDDVAREFIREQILSGAKIYNYTDDSGKIILWMDISDEETSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW79</accession>
    <name>D0YW79_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">1-deoxy-D-xylulose 5-phosphate reductoisomerase</fullName>
            <shortName evidence="7">DXP reductoisomerase</shortName>
            <ecNumber evidence="7">1.1.1.267</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">1-deoxyxylulose-5-phosphate reductoisomerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">2-C-methyl-D-erythritol 4-phosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">dxr</name>
        <name evidence="11" type="ORF">VDA_001364</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>2-C-methyl-D-erythritol 4-phosphate + NADP(+) = 1-deoxy-D-xylulose 5-phosphate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:13717"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
            <dbReference type="ChEBI" id="CHEBI:58262"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.267"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 1/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the DXR family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.267" evidence="7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297927.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001364"/>
    <dbReference type="EnsemblBacteria" id="EEZ40339">
        <property type="protein sequence ID" value="EEZ40339"/>
        <property type="gene ID" value="VDA_001364"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0743">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1200722at2"/>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00092"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030604">
        <property type="term" value="F:1-deoxy-D-xylulose-5-phosphate reductoisomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070402">
        <property type="term" value="F:NADPH binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00183">
        <property type="entry name" value="DXP_reductoisom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003821">
        <property type="entry name" value="DXP_reductoisomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013644">
        <property type="entry name" value="DXP_reductoisomerase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013512">
        <property type="entry name" value="DXP_reductoisomerase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026877">
        <property type="entry name" value="DXPR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036169">
        <property type="entry name" value="DXPR_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30525">
        <property type="entry name" value="PTHR30525"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08436">
        <property type="entry name" value="DXP_redisom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02670">
        <property type="entry name" value="DXP_reductoisom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13288">
        <property type="entry name" value="DXPR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006205">
        <property type="entry name" value="Dxp_reductismrs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69055">
        <property type="entry name" value="SSF69055"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00243">
        <property type="entry name" value="Dxr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6 7" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 7" id="KW-0521">NADP</keyword>
    <keyword evidence="5 7 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DXP_reductoisom" evidence="8">
        <location>
            <begin position="4"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="DXP_redisom_C" evidence="9">
        <location>
            <begin position="146"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="DXPR_C" evidence="10">
        <location>
            <begin position="271"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="7"/>
            <end position="36"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="152"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ40339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="398" mass="42950" checksum="BFDCFD99BC6CC02E" modified="2010-01-19" version="1">MRKLTILGATGSIGSSTLAVVAKNPEQFEVTALAAGSNVEKMLELCCYWKPKFAAMASETAANELTEKLIEQGLTTKVLSGEKGLCQVAELEEVDTVMAAIVGAAGLVPTMAAVKKGKRILLANKEALVMTGQIFIDACEQYGAELLPVDSEHNAIFQSLPADIQVRMGRCDLAKHGVSKVLLTGSGGPFRYTDIAELETVTPEMAIAHPNWSMGPKISVDSATMMNKGLEYIEARWLFNASREEMEVIIHPQSVIHSMVQYKDGSVIAQMGMPDMCTPIACAMAYPHRVDAGVAPLDFSQIGEFTFLKPDYDRYPCLKLAMDACYQGQAATTALNAANEIAVGAFLDNKIGFTDIARINAAVLAVASKEEPKDIDDVLELDRQARQLALDEIKKVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWB4</accession>
    <name>D0YWB4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Aromatic amino acid permease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_001377</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Involved in transporting aromatic amino acids across the cytoplasmic membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 8">Cell inner membrane</location>
            <topology evidence="2 8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the amino acid/polyamine transporter 2 family. Mtr/TnaB/TyrP permease subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297964.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001377"/>
    <dbReference type="EnsemblBacteria" id="EEZ40352">
        <property type="protein sequence ID" value="EEZ40352"/>
        <property type="gene ID" value="VDA_001377"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="935253at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015173">
        <property type="term" value="F:aromatic amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018227">
        <property type="entry name" value="Amino_acid_transport_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013059">
        <property type="entry name" value="Trp_tyr_transpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46997">
        <property type="entry name" value="PTHR46997"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03222">
        <property type="entry name" value="Trp_Tyr_perm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00166">
        <property type="entry name" value="AROAAPRMEASE"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00837">
        <property type="entry name" value="araaP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="4 8" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="33"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="113"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="143"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="177"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="215"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="243"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="272"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="321"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="374"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU367149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ40352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="403" mass="42915" checksum="96674C050FCD2DD2" modified="2010-01-19" version="1">MSKPSTLGGACIIASVCVGAGMLGLPSAGAGAWTLWSMAAISFTMIMMTLSGWLLLEALKHYEFKSSFNTVAKDVLSKKVNFINNLSLYFVGGILLYAYISTSGMIFSEIIGVSRQVASVIFVAICSAFVLHSTRAVDRISIVLILFMIISFILGISGLASHVSVPVLLDNAKGETHYSAYALALLPVALTSFGYHHSVSTMRDYYQDEHRAKKAILGGTMIALTFYLVWVICIFGNLPRDSFGPVVSAGGGVDVLMSALNSAIDSNSIKQALHIFSIAAVVSSFIGVGLGVFDYLADFFGFADTKQGRLKTWSVTFLPPLVFSLIAPFGFVTAIGLAGAAATIWACIIPAMLAKKLRNRETVQQGFVVPGGNITIYVVIGFGVLTAAFHLLAMANLLPVFKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWB9</accession>
    <name>D0YWB9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Lipoprotein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_001382</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the nlpA lipoprotein family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297973.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001382"/>
    <dbReference type="EnsemblBacteria" id="EEZ40357">
        <property type="protein sequence ID" value="EEZ40357"/>
        <property type="gene ID" value="VDA_001382"/>
    </dbReference>
    <dbReference type="GeneID" id="57339706"/>
    <dbReference type="eggNOG" id="COG1464">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1230456at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004872">
        <property type="entry name" value="Lipoprotein_NlpA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30429">
        <property type="entry name" value="PTHR30429"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03180">
        <property type="entry name" value="Lipoprotein_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002854">
        <property type="entry name" value="MetQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00363">
        <property type="entry name" value="TIGR00363"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="lipid moiety-binding region" description="S-diacylglycerol cysteine" evidence="5">
        <location>
            <position position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR002854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR002854-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="274" mass="29650" checksum="B67A6423C4AF5D38" modified="2010-01-19" version="1">MAVSLKHLFAVAGIASTLVLTGCGEKETATTAVDQNKVKIGVMAGAEEQVAEVAAKEAKEKYGLDVELVTFTDYVSPNAALADGSIDANAFQHKPYLDQQINDRGYKFTVAGNTFVYPIAAYSNKIKSLDELKDGAIVAVPNDPTNLGRSLLLLQQKGLLKLKENSGLSATVLDIVENPKNLQIKELEAAQLPRSLDDVDFAIINTTYASSLNLTPEKDGLFVEDKESPYVNLIVARTDNVNAENVQKFVKSYQSDTVYNSAKDIFKGGVVKGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWG2</accession>
    <name>D0YWG2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Serine-type D-Ala-D-Ala carboxypeptidase</fullName>
            <ecNumber evidence="4">3.4.16.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">VDA_001421</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the peptidase S11 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.4" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001421"/>
    <dbReference type="MEROPS" id="S11.003"/>
    <dbReference type="EnsemblBacteria" id="EEZ40395">
        <property type="protein sequence ID" value="EEZ40395"/>
        <property type="gene ID" value="VDA_001421"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1686">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009002">
        <property type="term" value="F:serine-type D-Ala-D-Ala carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015956">
        <property type="entry name" value="Peniciliin-bd_prot_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018044">
        <property type="entry name" value="Peptidase_S11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012907">
        <property type="entry name" value="Peptidase_S11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037167">
        <property type="entry name" value="Peptidase_S11_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001967">
        <property type="entry name" value="Peptidase_S11_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07943">
        <property type="entry name" value="PBP5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00768">
        <property type="entry name" value="Peptidase_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00725">
        <property type="entry name" value="DADACBPTASE1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00936">
        <property type="entry name" value="PBP5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69189">
        <property type="entry name" value="SSF69189"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 15" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="9" id="KW-0133">Cell shape</keyword>
    <keyword evidence="11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="8 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="domain" description="PBP5_C" evidence="14">
        <location>
            <begin position="175"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR618044-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEZ40395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="285" mass="31787" checksum="515F20E5126F193F" modified="2010-01-19" version="1">MFLEVGKTVKVSDLNRGIIVDSGNDACVAMAEHVAGSQESFVDLMNAWAKNVGMKSTHYANVHGLDNPDLYTTPYDLSLLARAIIRDTPNEFKIYSEKSFTYNGITQYNRNGLLWDKSLNVDGMKTGHTNNAGYSLVSTATEGKMRLISVVMGTKSPNARKAESKKLLNYGFRFFDTVSPNKANAPLVSEKVWMGDTDTVELGVTKDTYVTLPRTQTKDLKASFVINKELRAPIKKGEQLGTLYYRVGDQDVAQYPLVALNDVNEGSLFSRLVDYVMMLFQSWFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWK7</accession>
    <name>D0YWK7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001498</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298161.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001498"/>
    <dbReference type="EnsemblBacteria" id="EEZ40472">
        <property type="protein sequence ID" value="EEZ40472"/>
        <property type="gene ID" value="VDA_001498"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1216">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="865276at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="6"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="311" mass="36097" checksum="D8755B6E7B4F81D8" modified="2010-01-19" version="1">MNPKISVIIAAYNAEKHIKETIESLTNQYYDNLEVIVINDGSTDSTNSILTELKKNYCNLIIRNIKNNGVSNARNNGIEIATGEYISFLDADDIVECDFYSCLYEESYSKSLICAKNIYNMYSSEYISPWIENNKFDSNFYKNKIAVYIWGKLYKKSFLDEHNIRFDTKLRIGEDFLFNIICLSKLNHDDIQIVDNTSKFLYRITPDSLSHKTTTESITNRKQSAESIYQILKTEYNISDALFVYVKTYLKTMSIKLIKENQFKLLLNMLKMEAKNNKLTLAKIVSLSLNTKDTIYLSFILLLINIIRIMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWN6</accession>
    <name>D0YWN6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Phosphotransferase system fructose-specific</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">VDA_001492</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001492"/>
    <dbReference type="EnsemblBacteria" id="EEZ40466">
        <property type="protein sequence ID" value="EEZ40466"/>
        <property type="gene ID" value="VDA_001492"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1299">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1445">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1762">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022877">
        <property type="term" value="F:protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00211">
        <property type="entry name" value="PTS_IIA_fru"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05569">
        <property type="entry name" value="PTS_IIB_fructose"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016152">
        <property type="entry name" value="PTrfase/Anion_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002178">
        <property type="entry name" value="PTS_EIIA_type-2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036095">
        <property type="entry name" value="PTS_EIIB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013011">
        <property type="entry name" value="PTS_EIIB_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003501">
        <property type="entry name" value="PTS_EIIB_2/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003352">
        <property type="entry name" value="PTS_EIIC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013014">
        <property type="entry name" value="PTS_EIIC_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004715">
        <property type="entry name" value="PTS_IIA_fruc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003353">
        <property type="entry name" value="PTS_IIB_fruc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006327">
        <property type="entry name" value="PTS_IIC_fruc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00359">
        <property type="entry name" value="PTS_EIIA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02378">
        <property type="entry name" value="PTS_EIIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02302">
        <property type="entry name" value="PTS_IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52794">
        <property type="entry name" value="SSF52794"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55804">
        <property type="entry name" value="SSF55804"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00829">
        <property type="entry name" value="FRU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00848">
        <property type="entry name" value="fruA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01427">
        <property type="entry name" value="PTS_IIC_fructo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51094">
        <property type="entry name" value="PTS_EIIA_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51099">
        <property type="entry name" value="PTS_EIIB_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51104">
        <property type="entry name" value="PTS_EIIC_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-0598">Phosphotransferase system</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="7 16" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="264"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="305"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="356"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="388"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="433"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="470"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="533"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="573"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="domain" description="PTS EIIA type-2" evidence="13">
        <location>
            <begin position="1"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="PTS EIIB type-2" evidence="14">
        <location>
            <begin position="136"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="PTS EIIC type-2" evidence="15">
        <location>
            <begin position="257"/>
            <end position="593"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EEZ40466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="608" mass="62790" checksum="1C5D1E6B8F0AC62C" modified="2010-01-19" version="1">MAEMLTQQGKVADKEQFIADIYAREELGNTGFEEGVALPHAKSAAVASPAVAIGVSRQGIEYGAEDGLPSKLFFMIASPDGGANHHIEVLAELSSKLIEDGFIDAFLAAKTPEEALNLLLADKKEVVAVEQNKGLIIGVTGCPAGVAHTYLAAEALEKAGAELGYEVKVETNGSIGVKNSPTAEEIARAEAIVVSCDKQVDMARFAGKKLIKTGVKAPIKDGKGVIQQALVAKPFEADGDDTSDSSESKVAQTRSNLYRYLMNGVSHMIPFVVTGGLLIALSLAIGGQPTDAGMQIPAGSMWQKVLDVGVVAFQLMIPILAGYIAFAIGDRPALAPGFIGGWIANTGSFYDASAGTGFIGAIVAGLLVGYFVRWVATRNYHKMVQPLVPILIAPITGTLFIAGLFIFVIGAPIASLMDNMNAMLTEMSTGNVVLLGIVLGGMAGFDMGGPFNKVAFLFSVGMIASGQTQFMGAMACAIPVAPLGMGIATVIGRKLNIFEDSEIEAGKAAGAMGLVGISEGAIPFAAQDPLSVIPANVIGSMVAAVMAFSFGITNSVAHGGPVVALLGAMNKPVLALICMATGAVVTALVAVSLKKYRKAKAERELAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWP1</accession>
    <name>D0YWP1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mutator family transposase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_001527</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">Required for the transposition of the insertion element.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the transposase mutator family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298221.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001527"/>
    <dbReference type="EnsemblBacteria" id="EEZ40501">
        <property type="protein sequence ID" value="EEZ40501"/>
        <property type="gene ID" value="VDA_001527"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3328">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="792870at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001207">
        <property type="entry name" value="Transposase_mutator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33217">
        <property type="entry name" value="PTHR33217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00872">
        <property type="entry name" value="Transposase_mut"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01007">
        <property type="entry name" value="TRANSPOSASE_MUTATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0814">Transposable element</keyword>
    <keyword evidence="4 6" id="KW-0815">Transposition</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="402" mass="46634" checksum="93F6F11004ED4EBB" modified="2010-01-19" version="1">MDKKALEAFAREAAKSIKTESDLDDFRKMLTKVTVETALNAELDEHLGYQKHQARTNSNSRNGYSGKSIITDDGEVDIEIPRDREASFEPQLIRKHQTRFQSMDDKILSLYAKGMTTREIVATFKEMYDADVSPTLISKVTDSVLEQVIEWQSRPLDEVYPIVYLDCIVIKVRQDKQVINKAVYLALGVNMEGQKELLGMWLSETEGAKFWLNVLTELQNRGVKDILIACVDGLKGFPDAINTVFPETQIQLCIVHMVRNSVKYVPWKDYRAVTVDLKKIYQSATEDEALLALEQFSARWDSKYPQISRSWTTHWDNLNTLFNYPEDIRRAIYTTNAIESLNSVIRKAIKKRKLFPTDESARKVIYLAIRDASKKWTMPIRNWRQALNRFMIMFEDRLSEYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWR3</accession>
    <name>D0YWR3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Outer membrane protein A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_001460</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpA family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298099.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001460"/>
    <dbReference type="EnsemblBacteria" id="EEZ40434">
        <property type="protein sequence ID" value="EEZ40434"/>
        <property type="gene ID" value="VDA_001460"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2885">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3637">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1082122at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046930">
        <property type="term" value="C:pore complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015288">
        <property type="term" value="F:porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07185">
        <property type="entry name" value="OmpA_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006665">
        <property type="entry name" value="OmpA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036737">
        <property type="entry name" value="OmpA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000498">
        <property type="entry name" value="OmpA-like_TM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00691">
        <property type="entry name" value="OmpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01389">
        <property type="entry name" value="OmpA_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103088">
        <property type="entry name" value="SSF103088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51123">
        <property type="entry name" value="OMPA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0626">Porin</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019776" evidence="6">
        <location>
            <begin position="25"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="domain" description="OmpA-like" evidence="7">
        <location>
            <begin position="225"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ40434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="339" mass="35719" checksum="1DB5C5AFA030137E" modified="2010-01-19" version="1">MKLKSLSLSVLAALSLGVATSAMAADATATDANTVATKSAASGHWYSGEGHGWWIGGALGMGYVGNNDEGVFGGQTNAPSVKLDAGYDFNQYVGVYGSYDFMYDLGNADMHIGTLGIKGNLPLTQKLSAFGKVGASYIYADGQSFHHQATHLHSDSFSATAGLGLSYQITNALSTQVGADYYQNLDTTNGHADLTQAYWGMTYKFGQPVAPAVITNEVEVVKEVAVQTATRSTYVLPYQNGQTKLNDYGRYNLNEVVATMNANPEVTAQIVGRTDAVGSKAINEKVSNARAQGVAEYLEANGIDASRLTVSSVANNDPLVAGNSNGANLIERSVQIILK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX35</accession>
    <name>D0YX35_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hypothetical membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001891</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298884.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001891"/>
    <dbReference type="EnsemblBacteria" id="EEZ40859">
        <property type="protein sequence ID" value="EEZ40859"/>
        <property type="gene ID" value="VDA_001891"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1289">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1451695at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006726">
        <property type="entry name" value="PHBA_efflux_AaeB/fusaric-R"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04632">
        <property type="entry name" value="FUSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="112"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="347" mass="40187" checksum="7E72D5CA6F2CB4E7" modified="2010-01-19" version="1">MNYYERFAIRYYRFLYILRVFVTFSLILSITRIFDIPYGTWALITAVTVMGSMPFIGGVLSKAKQRIWGTMLGALLGLSLYLIPVQFSWMHHFMFLAFILAAMYYTQEKYSYAALVTAITIAIVAGGGPEDFHAAMWRTINVLWAGMTALICSLYVFPSRATNHFLDLVSQFMDQSSQYYHQHNQELSMSTFNPISTTDLAKLIDQQQALLPHALKESGPNKQVITNALLIEKRIYTMLETLVSTRWDTQSGQEKISDMPGLTQAKEQLARRFERLSRQVIDKNVTPIHKDEIKLLHLLPNREHHEQDDTSDISYFGYLWLNRELARQFSKLTHTLAKLFQYHDEIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX54</accession>
    <name>D0YX54_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative Hit Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001845</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298803.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001845"/>
    <dbReference type="EnsemblBacteria" id="EEZ40813">
        <property type="protein sequence ID" value="EEZ40813"/>
        <property type="gene ID" value="VDA_001845"/>
    </dbReference>
    <dbReference type="GeneID" id="57342037"/>
    <dbReference type="eggNOG" id="COG0537">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1934382at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019808">
        <property type="entry name" value="Histidine_triad_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001310">
        <property type="entry name" value="Histidine_triad_HIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011146">
        <property type="entry name" value="HIT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23089">
        <property type="entry name" value="PTHR23089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01230">
        <property type="entry name" value="HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00332">
        <property type="entry name" value="HISTRIAD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="SSF54197"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00892">
        <property type="entry name" value="HIT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51084">
        <property type="entry name" value="HIT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HIT" evidence="2">
        <location>
            <begin position="6"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Histidine triad motif" evidence="1">
        <location>
            <begin position="99"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="116" mass="13126" checksum="FBB2061BBFC364E5" modified="2010-01-19" version="1">MVEETIFSKIIRREIPADIVYQDELVTAFRDINPRAPSHVLIIPNKLIPTVNQVQVEDEIMMGRMFTVARKIAEQEGIAEDGYRLIVNCNPHGGQEVYHIHMHLLGGRPLGPMLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX68</accession>
    <name>D0YX68_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_001833</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298785.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40801">
        <property type="protein sequence ID" value="EEZ40801"/>
        <property type="gene ID" value="VDA_001833"/>
    </dbReference>
    <dbReference type="GeneID" id="57342051"/>
    <dbReference type="eggNOG" id="COG1584">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1399490at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000791">
        <property type="entry name" value="Gpr1/Fun34/SatP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01184">
        <property type="entry name" value="Gpr1_Fun34_YaaH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01114">
        <property type="entry name" value="GPR1_FUN34_YAAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="123"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="145"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="195" mass="20948" checksum="234545AB3D82198B" modified="2010-01-19" version="1">MSTKLANPAPLGLMGFGMTTILLNIHNAGFFPLDSMILAMGIFYGGLGQVLVGMMCFKRGDTFGTTAFTSYGLFWLTLVGLIVMPKMGFAASPAHFMGWYLGLWGVFTAFMFIGSLRYPRAKQVVFGSLTILFFLLAARDFTGSALIGTIAGLEGIFCGASAIYFAMAQVLNAEYGRTILPVGELKKEETLKAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXA0</accession>
    <name>D0YXA0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Nitric oxide reductase FlRd-NAD(+) reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_001640</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FAD-dependent oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298425.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001640"/>
    <dbReference type="EnsemblBacteria" id="EEZ40613">
        <property type="protein sequence ID" value="EEZ40613"/>
        <property type="gene ID" value="VDA_001640"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0446">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1149616at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041364">
        <property type="entry name" value="Rbx-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18113">
        <property type="entry name" value="Rbx_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="4">
        <location>
            <begin position="4"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="Rbx_binding" evidence="5">
        <location>
            <begin position="307"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF18113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="383" mass="41407" checksum="5A9189474295205B" modified="2010-01-19" version="1">MSHPIIVIGSGFAAYQWVKSFRKLDQDTEITIITADNGDDYSKPDLSHVFSRQQRATDLVKQSATEFAQANSVKLITNTYVTAIDPQAKTVSIDDQVLTYSNLILATGSRAFVPPFAGNATDEIITLNSLQEFEQAQERLITAKRITVLGAGLIGTEIAMDLASSHKQVTLCDKASSILPAMLPPFLGSEVQHTMALNGVDFKLNRGISAINRHHQEMLVELDNGEVISSDVVIAAMGLRSNTQLAQQAGLMVNHGIVVNQYMQTSDANIYALGDCAELYGRVRAFIQPTMLAAMALAKTLAGTATPVRLPASLVKAKTPWIPLNLAGKTVGSELTWEIQRNSDGYVAKAFHVETSELSGFIVSHDQAKAAFPLLRLLPGEVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXL9</accession>
    <name>D0YXL9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001760</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298644.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40728">
        <property type="protein sequence ID" value="EEZ40728"/>
        <property type="gene ID" value="VDA_001760"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031MCM">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="262" mass="30634" checksum="88EEDBB7E2CC1647" modified="2010-01-19" version="1">MVGSDDYALFYRTACNIFESGFEFINEADDNYYFMNVAAIKLLKHINTTEMLMTNELNLNHVEQGGTYYDTSSVIALLRVSYENLVTIAYHYFSDELDKDRLDWYTLLGYKNRAKNKVVAGTPELEAKIREEQQIIDELSSRLRLNSFKSSRKNEWKPCGWYELGKQLGIPTFVCDKYSFWSSHTHTGFDSLMQVNTAHKAHPTEEIKRNQINYLFMCSVLVYFIDGYVRVLSKLGYPYISDFELDDVKSFLRFMNSLDRTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXP3</accession>
    <name>D0YXP3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001746</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298616.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40714">
        <property type="protein sequence ID" value="EEZ40714"/>
        <property type="gene ID" value="VDA_001746"/>
    </dbReference>
    <dbReference type="GeneID" id="57342164"/>
    <dbReference type="eggNOG" id="ENOG5031NJE">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1923191at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="70" mass="8101" checksum="6E66D4F3A29F08EF" modified="2010-01-19" version="1">MKKMKSSYRLQIIKEVAQRHQLLESGDPMATHISHLLNQSKPEKAPPMFNGNHYDEHAGGWVSNMWDLNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXU6</accession>
    <name>D0YXU6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002109</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299460.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41077">
        <property type="protein sequence ID" value="EEZ41077"/>
        <property type="gene ID" value="VDA_002109"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5033N9X">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1926494at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="101" mass="11651" checksum="67DBC58C7E9680FC" modified="2010-01-19" version="1">MTYKASDLNYRGENCGVHNWITDQGQSFYWHPDWLHIAEDETGLHGKEEIALPAGEHASKEHAVTAILRKLNTWAVDHFEKHPDLEQEAKKAEEELKKSDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXW0</accession>
    <name>D0YXW0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Formate dehydrogenase-O major subunit</fullName>
            <ecNumber evidence="11">1.2.1.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">VDA_002123</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="1.2.1.2" evidence="11"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299493.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002123"/>
    <dbReference type="EnsemblBacteria" id="EEZ41091">
        <property type="protein sequence ID" value="EEZ41091"/>
        <property type="gene ID" value="VDA_002123"/>
    </dbReference>
    <dbReference type="GeneID" id="57341747"/>
    <dbReference type="eggNOG" id="COG0243">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3383">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="83812at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043546">
        <property type="term" value="F:molybdopterin cofactor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006657">
        <property type="entry name" value="MoPterin_dinucl-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006656">
        <property type="entry name" value="Mopterin_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006963">
        <property type="entry name" value="Mopterin_OxRdtase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027467">
        <property type="entry name" value="MopterinOxRdtase_cofactor_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04879">
        <property type="entry name" value="Molybdop_Fe4S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00384">
        <property type="entry name" value="Molybdopterin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01568">
        <property type="entry name" value="Molydop_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00926">
        <property type="entry name" value="Molybdop_Fe4S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="SSF50692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51669">
        <property type="entry name" value="4FE4S_MOW_BIS_MGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00551">
        <property type="entry name" value="MOLYBDOPTERIN_PROK_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7 9" id="KW-0408">Iron</keyword>
    <keyword evidence="8 9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="6 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0574">Periplasm</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="domain" description="4Fe-4S Mo/W bis-MGD-type" evidence="10">
        <location>
            <begin position="63"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ41091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="953" mass="106840" checksum="AD413018F1DBBF6E" modified="2010-01-19" version="1">MKLTKRSDKVSKDENQLGISRRSFIRNSSIAAAGGIAGASMFAPGMMKKAQAAEEFIPTDAPKEVKRTICSHCSVGCGIYAETQEGVWTHQEPAFDHPFNAGGHCAKGAALREHGHGARRVKYPMKLVNGKWQRLSWDQALSEVSQQILKIREESGPDSVYWLGSAKHNNEQAYMFRKMVSMWGTNNVDHQARICHSTTVAGVANTWGYGAMTNSLNDMHNCKSILFIGSNPAEAHPVAMQHILIAKETNDCKIVVVDPRRTRTAAKADHYVSLRPGSDVAFIWGVLFHIFQNGWEDKEFIRQRVYGMDQVRAEVAKWNPKEVERVTGVPEEQVYQTAKMLSENRPGCVVWCMGGTQHTTGNNNTRAYCILELALGNMGKSGGGANIFRGHDNVQGATDFGVLSDNLPGYYGLSEGAWKHWSRVWDVDYEWMQGRFDPNTYAGAKPMNSKGIPVSRWIDGVLENKDKIAQRDNIRAMFYWGHAVNSQTRGPEMRKAMGKLDLMVIVDPYPGVASVMNGRTDNVYLFPASTQFETYGSVTATNRSIQWRDQVIDPLFESKPDHEIMYLLTQKLGYADKLFKNIKVENNRPVIEDITREYNKGMWTIGYTGQSPERLKEHQKNWHTFDRTSLEAIGGPANGETYGLPWPCWGTPEMNHPGTHILYDTSKTVAQGGGNFRARFGVEHDGQSLLAVDSYSLGCELEDGYPEFTDKMLKQLGWWDDLTAEEKQAAEGKNWKTDLSGGIQRVAIKHGCIPYGNAKARTVVWTFPDAVPLHREPLYTPRRDLVVDYPTWDDKANLFRLPTLYKSIQDKDVSGEYPIILTSGRLVEYEGGGEETRSNPWLAELQQEMFVELNLKDANDRGIKDGEMVWVEGAEKGRIKVKAMVTPRVREGLAFLPFHFGGEFEGESLRSHYPEGCAPYVSGEAANTATTYGYDPVTQMQETKVTLCNITKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXY8</accession>
    <name>D0YXY8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DotU domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002151</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299548.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002151"/>
    <dbReference type="EnsemblBacteria" id="EEZ41119">
        <property type="protein sequence ID" value="EEZ41119"/>
        <property type="gene ID" value="VDA_002151"/>
    </dbReference>
    <dbReference type="GeneID" id="57341711"/>
    <dbReference type="eggNOG" id="COG3455">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1650600at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.590">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017732">
        <property type="entry name" value="T4/T6SS_DotU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038522">
        <property type="entry name" value="T4/T6SS_DotU_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09850">
        <property type="entry name" value="DotU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03349">
        <property type="entry name" value="IV_VI_DotU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="228"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="DotU" evidence="2">
        <location>
            <begin position="47"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="266" mass="30431" checksum="472233CEE9764958" modified="2010-01-19" version="1">MDETLDREKATKQPEGYFDGVLFDNVKNINQDQDFWFKLRGNNINALIDAATPLLGMSLRIRNLSHCDNIDEIYHQSVEEIKAIEVELTEAGYEHAVILAYRYVLCSFIDEAVMSTPWGADSSWAECSLLTRFHNETWGGEKVFSILSRLESEPARYQELLAFIYLCLTLGFEGRYKVMNNGKEEFEKVVANLYEILRRLADKDPEALTSATEHVVATKYKLTKQVPIWTVFAGFALTWVVIFIGYSIALHNKSGDVLEQLNQILQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY14</accession>
    <name>D0YY14_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Pyocin killing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_002177</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299596.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002177"/>
    <dbReference type="EnsemblBacteria" id="EEZ41145">
        <property type="protein sequence ID" value="EEZ41145"/>
        <property type="gene ID" value="VDA_002177"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4104">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1695665at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019835">
        <property type="term" value="P:cytolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042742">
        <property type="term" value="P:defense response to bacterium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008727">
        <property type="entry name" value="PAAR_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003616">
        <property type="entry name" value="Post-SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016128">
        <property type="entry name" value="Pyosin/cloacin_T_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036302">
        <property type="entry name" value="Pyosin/cloacin_T_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05488">
        <property type="entry name" value="PAAR_motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06958">
        <property type="entry name" value="Pyocin_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69369">
        <property type="entry name" value="SSF69369"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50868">
        <property type="entry name" value="POST_SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0044">Antibiotic</keyword>
    <keyword evidence="1" id="KW-0929">Antimicrobial</keyword>
    <keyword evidence="3" id="KW-0078">Bacteriocin</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Post-SET" evidence="4">
        <location>
            <begin position="36"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="490" mass="52433" checksum="354CBA979CF8574B" modified="2010-01-19" version="1">MGDIITVGCKTSTGGSVITGSGHVKINGLSQALLGDTATCLCGSKSCRGQGPIVQQSSRAANINGTNVARVGDFVDTGCGNCYLIASNHNVSLGTSTATPLSMGNGISIGNSVSINTGGLTTTYSQSFSSPIQTQTNKVFAKSPKAPWGSIDVGQLREPASSIGSMGVYAAGSMDAVASTGLGATALSRISGVALADIAGFSMQVIGRSGVLLALSPTQLGDGTLYGQEEVKAKSGVETRVRFGFDTDGNIHGYHVDNAVIPNRTVEHIGDKFVVDLEPGIRIEWVPTTTEIAGTKILTNPIPDIDLHTIYIHPEKDQGEEFANTYVTPISDVDLNDYILIFPEETGLPPLYIVYSKPPVKMLEVDLYGNFKGRPRNGTHADHMPSQRAASTYLQRKLAGFADDQQIKKQMNFVATVIIPAKVHQKYSETYGGRNTPTQIAKDANNLRQAVDNNFDAIKPWMLEEGFNESELENARNKMHQLNKENGWYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY68</accession>
    <name>D0YY68_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter permease protein YnjC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_002231</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299699.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002231"/>
    <dbReference type="EnsemblBacteria" id="EEZ41199">
        <property type="protein sequence ID" value="EEZ41199"/>
        <property type="gene ID" value="VDA_002231"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4135">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1783638at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="7"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="58"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="92"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="142"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="203"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="245"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="308"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="353"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="387"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="421"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="475"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="525"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="54"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="357"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="553" mass="62611" checksum="096CD52900ECB5D9" modified="2010-01-19" version="1">MRRSLFILTIIIVFLPIIPGLFGVILPAFSYIPTLGLHHISLQGFYQVFQWPHVTDSIVITVWSGLISTAISLYLTYSFLRLFWYTDQWKKLEAWLSPLLAIPHVAFAIGLVFLVSPTGWLNRLLDLISSKLAIINLAQDPYALGLILVLTIKETPFLILMSIAVLQQLNTPQLVRISASLGYSPQQTWQKVIFPQWLPKIRLPLYAVVAYGLSVVDLNLIIGPSQPSSFSVLVWQWFNDSDLSLLPRATAGALVLLLIAGIVLCVVRSLEWVILHHRRHWLIKGTNSDYPPANGWFVSTAPLRKASLLIFLSLPIVTLPLLGIWSFALRWRFPDILPSRWSERFWQQEIDQITQLLTTSTLFAVLSALICLILVIGSLEFRDKYQLNIPVVIIAIPLVVPQLSLLFGIQITTLYFPTNTYFLWVLWGHIFYVFPYMYLALDGTWRSYDPRYSYTAASLGISPIRVWWQVKRPQLMTGIIFAFAMGLSVSFAQYLPTQMLGAGRITTLTTEAVALASGQDRRVTAIYGLLQGLLPLVSFTLALIFSKKYRINS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-06-02" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY82</accession>
    <name>D0YY82_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002245</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41213">
        <property type="protein sequence ID" value="EEZ41213"/>
        <property type="gene ID" value="VDA_002245"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="38" mass="4534" checksum="69B6756394AEAA86" modified="2010-01-19" version="1">MENEAVSQQKQQKPTRPADPNRIAYIQQLRKELKLVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY84</accession>
    <name>D0YY84_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Oxalate/formate antiporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_002247</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002247"/>
    <dbReference type="EnsemblBacteria" id="EEZ41215">
        <property type="protein sequence ID" value="EEZ41215"/>
        <property type="gene ID" value="VDA_002247"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2223">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="68"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="125"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="215"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="249"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="279"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="303"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="338"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="366"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="1"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="402" mass="42352" checksum="8479EA4B90AF1A29" modified="2010-01-19" version="1">MQILFAGFCINLCMGILYAWSVFKKALVVDLGWSNADASLPYTVAIITFSLSLLVAGILQDRMGPRKVLILGTVMVGLGMIVSSFANSPMMLVLTFGILTGCGIGFGYACLSPSAMKWFHPSKKGLVNGLIAAGFGLAAVYLAPLTSMLISTYGINTSFLILGIAVIIIAVPLAFTINNPPADYVPEAPKGYDATNKSTKIVDINWRGMLKTPQFYSLWVMYAFASAAGLMIIGNITSIAATQANITDAAYLVVILAIFNSGGRVVAGILSDKIGGVKTLMLAFIMQGINMVMFASFKTDFTLIIGAAVAGVGYGTLLAVFPSIIADFYGLKNYGANYGVLYTAWGVSGFIGPVVAAYAVDTTGTYTLAYTVCSVMIAVAVVLSFITKKVDAEALEKKLASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYA7</accession>
    <name>D0YYA7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_002270</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299765.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002270"/>
    <dbReference type="EnsemblBacteria" id="EEZ41238">
        <property type="protein sequence ID" value="EEZ41238"/>
        <property type="gene ID" value="VDA_002270"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1108236at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="64"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="92"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="120"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="147"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="178"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="210"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="245"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="296"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="329"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="359"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="386"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="515"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="23"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="544" mass="57757" checksum="5B5D09904AEF3E28" modified="2010-01-19" version="1">MDNTSKLAPDASNAKTGIAKWFSLVILLMAQVGTMGDNSGLSVATASLINELGASVSDIAFANAMYPLIAGACMIAGGMLGLIWGWKRLFQVGALLLCLAEIIAAYTDNIQVFIFAARSLSGFGASFLIPAVLGLIVGIYTDTKDRAIAFGAVAAAVGVANTAAPLVFGFLIDKFDYRVAFEALAIYFGVVFVLGFALEKIEKPTVKIKFDFVGTILVSIGLLAVIVGLLKISEWGLISPLSPSFHILGISPALPLVLFGIAVLLIFLKWENQFEIKNGACLMPQSFIKTPQLRDGLYMCGMVFFVLGAYILIGITYCQLVAGYSATDTALLLMVFSTGMLITSLATPTKFAHVSCRKLCMIGIGFCVLAAISGALGTELDSVNMIFFGSALFTGLGCGVIASQASLIVTAAVNQRDATQSGGVQATSRNIGQTIGIAVLGSVLMFSLTNMVKSDAANSDLISVQTKQQVEQIASIPFLSDKDFTQLVETNITEKQDYPVLIDINREARKSAAQLSWLVLAAMCFISIFTLTKNIPNYSLSKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYB0</accession>
    <name>D0YYB0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">UvrABC system protein C</fullName>
            <shortName evidence="7">Protein UvrC</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Excinuclease ABC subunit C</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">uvrC</name>
        <name evidence="11" type="ORF">VDA_002273</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Interacts with UvrB in an incision complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the UvrC family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002273"/>
    <dbReference type="EnsemblBacteria" id="EEZ41241">
        <property type="protein sequence ID" value="EEZ41241"/>
        <property type="gene ID" value="VDA_002273"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0322">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009380">
        <property type="term" value="C:excinuclease repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009381">
        <property type="term" value="F:excinuclease ABC activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00203">
        <property type="entry name" value="UvrC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000305">
        <property type="entry name" value="GIY-YIG_endonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035901">
        <property type="entry name" value="GIY-YIG_endonuc_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003583">
        <property type="entry name" value="Hlx-hairpin-Hlx_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001943">
        <property type="entry name" value="UVR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036876">
        <property type="entry name" value="UVR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004791">
        <property type="entry name" value="UvrC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001162">
        <property type="entry name" value="UvrC_RNase_H_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038476">
        <property type="entry name" value="UvrC_RNase_H_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01541">
        <property type="entry name" value="GIY-YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08459">
        <property type="entry name" value="UvrC_HhH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00465">
        <property type="entry name" value="GIYc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00278">
        <property type="entry name" value="HhH1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46600">
        <property type="entry name" value="SSF46600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82771">
        <property type="entry name" value="SSF82771"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00194">
        <property type="entry name" value="uvrC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50164">
        <property type="entry name" value="GIY_YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50165">
        <property type="entry name" value="UVRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3 7" id="KW-0228">DNA excision</keyword>
    <keyword evidence="5 7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4 7" id="KW-0267">Excision nuclease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0742">SOS response</keyword>
    <feature type="domain" description="GIY-YIG" evidence="9">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="UVR" evidence="8">
        <location>
            <begin position="182"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="UVRC" evidence="10">
        <location>
            <begin position="233"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ41241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="589" mass="67034" checksum="47EDB3A0E85F984D" modified="2010-01-19" version="1">MYNASDEVIYVGKAKDLKKRLSSYFRTNVAGEKTRALVKNIHKVDVTVTHTETEALILEHNYIKQYLPKYNVLLRDDKSYPYIFLSHHQHPRLSMHRGVKRRKGEYFGPYPDAGAVRESLHLMQKIFPVRQCEDSVYANRSRPCLMYQIGRCSAPCVKGYISDEDYQGQVQLARLFLQGKDRQVIAMLVEKMETASQNLDFEKAAVYRDQIQALRRVQEQQFVSHDTEDDLDVVGIAHENGMACIHALYIRQGKILGSRSYFPKMPADVELTEVLSSFVTQFYLNQAEGRVIPTNIILSEDLGDETAVISDTLSQLAGRKVVFKYHPRGNRARYLKLAQTNAKTALTSKLNHKMTIQERFFELQQALSLKPISRMECFDISHTMGEKTVASCVVFNQDGPYKPDYRRYNITGITGGDDYAAMAQVLERRYGKQMELDKIPDIIFIDGGRGQLSRAYDVVKPYMEDWPKRPLMIGVAKGTTRKPGLETLIFITGEEFSLPSDSPALHLIQHIRDESHNHAISGHRAQRAKVRKRSALEDIEGVGPKRRQALLKYMGGLQELKRASKEEIAKVPGISLALAEKIVDALHHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYH9</accession>
    <name>D0YYH9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002342</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299924.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002342"/>
    <dbReference type="EnsemblBacteria" id="EEZ41310">
        <property type="protein sequence ID" value="EEZ41310"/>
        <property type="gene ID" value="VDA_002342"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5033KX2">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1986268at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="186" mass="21020" checksum="F31DE55636677A77" modified="2010-01-19" version="1">MNPKASSYNNSIRLILLTLIAVLSCYYLWVLYKAATPNVSIAYKTYYIKQQNLYWDIDNPDLSLSIPKILKVEQNLPFLSRQGWSKDVIDHARQLESQGGLYFTVNQAIKQPIELTIDLTTPVTQSIDITVNQWHGTLQPSISQPNHLTTIIPATAFLAPKAVQQLTVLNSKPLSVQQITLESEHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYK5</accession>
    <name>D0YYK5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Putative ATP-binding component of a transport system</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_002368</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299969.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002368"/>
    <dbReference type="EnsemblBacteria" id="EEZ41336">
        <property type="protein sequence ID" value="EEZ41336"/>
        <property type="gene ID" value="VDA_002368"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4178">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="643917at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06472">
        <property type="entry name" value="ABC_membrane_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="73"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="153"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="194"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="39"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="367"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="408"/>
            <end position="415"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ41336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="582" mass="66539" checksum="98B78B841EA20D66" modified="2010-01-19" version="1">MKLTDSVQLSSRHFLGKVWQLAKPYWQSEEKWIARGLLFAIVILNLGMVYMSVILNKWNADFYNALQQIDKAAFTHLLIKFSLIAAGFIIIAIYRIYLNMMLQLRWRRWLTQVYFSDWLSHRVYYQLELEHGKTDNPDQRISEDINQFTSDTLGLALGLLNSVVTLASFITILWGLSGSMSVDLLGHHIEIPGAMVWAALLYAGIGSWIMHKIGRPLIGLNFMQQKFEADLRFSMIRLRENAEGVALYQGEKTEQQELELKFDSVWKNTWKIMRKQKQMVGFNSGYSQIASIFPLVITAPRFFSGAIKLGGMMQIVNAFGQVMDAMSWFVNSYASIASWKASVDRLTTYHEHMIEAREQTIKSQLHIKLSNQDHLTLSQCSVGLPNKEILFTLGNLSIAAGEHTLIAGPSGLGKSSLMKTIAGIWPFSQGEVERNNDALFLPQRPYLPIATLRDVLLYPQKDTLISDATLVEWMHKCSLSRFVDVLSERHNWAHVMSPGEQQRVALLRTFIQQPKWLFLDEATASLDEETEARMYQLLLDELPQTTLISIAHRSVVAKYHKQLLRGQRTDDHQVRWDKGAIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYM2</accession>
    <name>D0YYM2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Protein YciN</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002385</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002385"/>
    <dbReference type="EnsemblBacteria" id="EEZ41353">
        <property type="protein sequence ID" value="EEZ41353"/>
        <property type="gene ID" value="VDA_002385"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5032SBA">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019633">
        <property type="entry name" value="DUF2498"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038191">
        <property type="entry name" value="YciN_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10692">
        <property type="entry name" value="DUF2498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="69" mass="7908" checksum="596E83F8C80AF453" modified="2010-01-19" version="1">MIANQLIQDHDDYIPGMRATSVEEKMGVLVFKGEYFLDDEGLPTENTTHVFNMFKFLAHQLSPEFTLAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYP5</accession>
    <name>D0YYP5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator LacI family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_002408</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300036.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002408"/>
    <dbReference type="EnsemblBacteria" id="EEZ41376">
        <property type="protein sequence ID" value="EEZ41376"/>
        <property type="gene ID" value="VDA_002408"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1796334at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00036">
        <property type="entry name" value="HTHLACI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="2"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="328" mass="36882" checksum="1FBAB556BECE5760" modified="2010-01-19" version="1">MATLKDIATEAGVSLATVSRVLNDDPTLSVKEETKHRIFEIAEKLEYRTSSAKKSTLDKKINHHFLALYNYKQEAEVNDPYYLSIRHGVETQCDKLGVTLTNCYNSEIDVELNKVTGVLLVGRMHGSIIKKIPKRLSDHICYIDFTDNNSGYDCVDIDLVRISKQIIDFFVEQGYERIGFIGGHDEPNTPDIRENAFVEYGNLKGVVSEQDIYRGDFSSQSGYNLAKDMLEKGNYPKALFIASDSIAIGVLRAIHEFKLTIPDDIALISVNDIPTARFTFPPLSTVRIHSEMMGIQGVNLLVEKYRDGRALPLQVFVPSKLKLRGTTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYQ5</accession>
    <name>D0YYQ5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002418</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300053.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41386">
        <property type="protein sequence ID" value="EEZ41386"/>
        <property type="gene ID" value="VDA_002418"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG503367Y">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="237" mass="26304" checksum="8DA964F6084E798C" modified="2010-01-19" version="1">MTKMTLGSAMSKTVKSEKPLDLLADISDIILSELASSLESLPIFGLLFKGYNALNTIQGEISARKIYNFFYEIQNLRLEDKAKVMDEISRSKGGGDEAGLLLLDLVDKSDDNLKPKLIGKLFVACAFCEITTQQFLRLSSVVNNVFIDDLQKLKEVYEHNALSDQLKSIYTANGLMEISIKKPQKFSQGYTMSELGDAIFNQGLALEYSLTDDGKLLAKVCFETTEKIGNTLEKFGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYQ9</accession>
    <name>D0YYQ9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Polyhydroxyalkanoic acid synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_002422</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300061.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002422"/>
    <dbReference type="EnsemblBacteria" id="EEZ41390">
        <property type="protein sequence ID" value="EEZ41390"/>
        <property type="gene ID" value="VDA_002422"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3243">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="891360at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042619">
        <property type="term" value="P:poly-hydroxybutyrate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010963">
        <property type="entry name" value="PHA_synth_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010941">
        <property type="entry name" value="PhaC_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07167">
        <property type="entry name" value="PhaC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01838">
        <property type="entry name" value="PHA_synth_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PhaC_N" evidence="5">
        <location>
            <begin position="95"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="590" mass="67459" checksum="759B1735154DC5A1" modified="2010-01-19" version="1">MYQNFFSDYLVKLQETNQQWWHDFEANKAAVNSPLNKAMQEVNFEDTAKFFEQAANQPAAMLKVQTHWWEQQLQIWQNLVLSDPSKSVVEAELGDKRFANEAWQNELLYNFIKQSYLLFSKTYQDTIDSIEGVDEKTKERISFFSRQAINALSPSNFIATNPELLKMTLEQNGENLIAGLEKFKEDIESSADILKVRMTNNNAFRIGDDIATTEGDVVYRNDLFELIQYRPLTEKVHTTPLLIVPPFINKYYILDLTAKNSMVRWLLEQGHSVFMMSWRNPGKAQADTEFGDYITDGVVKAVSAIEDITGQQQVNAAGYCIGGTLLACTVAYYAAKRMKKRIKSASFFTTILDFSQPGEIGAFVNDTVVSAIEQQNKVKGYMDGRSLSVTFSMLRENSLYWNYYVDNYLKGKSPVDFDLLYWNSDSTNVAGPCHNFLLRDFYLENKLIQDKGVKIDGVWMDLNKIKIPSYFISTKEDHIALWQGTYRGALLTGGNKTFVLGASGHVAGIVNPPNKNKYGYWTNDNLDDSADEWLTNAEYAEGSWWTHWDQWLSQHNRQEQVEPYSPGSENYPVIDSAPGQYVKQVLPITE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYS4</accession>
    <name>D0YYS4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome d ubiquinol oxidase subunit II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_002437</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome ubiquinol oxidase subunit 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002437"/>
    <dbReference type="EnsemblBacteria" id="EEZ41405">
        <property type="protein sequence ID" value="EEZ41405"/>
        <property type="gene ID" value="VDA_002437"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1294">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003317">
        <property type="entry name" value="Cyt-d_oxidase_su2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43141">
        <property type="entry name" value="PTHR43141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02322">
        <property type="entry name" value="Cyt_bd_oxida_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000267">
        <property type="entry name" value="Cyt_oxidse_sub2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00203">
        <property type="entry name" value="cydB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="61"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="103"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="145"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="187"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="247"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="273"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="318"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ41405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="362" mass="39624" checksum="74F33BCC204A366B" modified="2010-01-19" version="1">MLCIGFAITDGFDMGVGMLSKVIGKTDTERRVMINSVAPHWDGNQVWLITAGGALFAAWPLVYATVFSGFYLAMILTLAALWLRPLAFDYRSKLAEPKWRDAWDNALFVGSFVPPLIFGVAFGNLLQGVPFELNNLLIPTYKGNLLGLLNPFALLCGVVSVLMILTQGAAYLQMKTTDAVHVRARAVAMKTSIATAVAFIIAGIWAHGLDGYVVTSTMDHFAPSNPLNKQVEVVSGALFLNYAQYPAMWIAPILAVVMPVLTMLASRAERAGFAFLFSSLTLAGVVLTFGFATFPFIMPSSIMPNVSLTIWDATSSELTLKIMTGVAFVMVPIILAYTSWCYYKMFGRLDNKFIEDNKNSLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYS8</accession>
    <name>D0YYS8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sialic acid utilization regulator RpiR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002441</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300097.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002441"/>
    <dbReference type="EnsemblBacteria" id="EEZ41409">
        <property type="protein sequence ID" value="EEZ41409"/>
        <property type="gene ID" value="VDA_002441"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1737">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="992687at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901135">
        <property type="term" value="P:carbohydrate derivative metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05013">
        <property type="entry name" value="SIS_RpiR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000281">
        <property type="entry name" value="HTH_RpiR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035472">
        <property type="entry name" value="RpiR-like_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01418">
        <property type="entry name" value="HTH_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01380">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51071">
        <property type="entry name" value="HTH_RPIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH rpiR-type" evidence="1">
        <location>
            <begin position="11"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="2">
        <location>
            <begin position="136"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="291" mass="31293" checksum="BD7052F5715FE299" modified="2010-01-19" version="1">MTAKTTAIKAGKVLDMIGSLQESLTPSAQRIADYVLDNAADVTRFSIAELSSAVNVGEATIIRFCRTLGFKGFQDFKMELAIELSTASSPNEKSLLDSDVTPSDSAELIGQKLHNTINNVLGETLNLLNFDTLAKVAKLLRSSHGVYFFGVGSSGITAEDAKNKLMRIGFNVDALTNNHFMYMKASLLHPGDLAIGISHSGNSLETTKALKLAKEAGATTVALTHNPRSSIAEYADYVLVNGNRQGKLQGDSIGTKISQLFVLDLIYALLVQEDMDGTQAQKLKTTQALDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYV4</accession>
    <name>D0YYV4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Histidinol dehydrogenase</fullName>
            <shortName evidence="5">HDH</shortName>
            <ecNumber evidence="5">1.1.1.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">hisD</name>
        <name evidence="12" type="ORF">VDA_002467</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>H2O + L-histidinol + 2 NAD(+) = 3 H(+) + L-histidine + 2 NADH</text>
            <dbReference type="Rhea" id="RHEA:20641"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
            <dbReference type="ChEBI" id="CHEBI:57699"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5 10">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5 10">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 9/9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6 11">Belongs to the histidinol dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.23" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300149.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002467"/>
    <dbReference type="EnsemblBacteria" id="EEZ41435">
        <property type="protein sequence ID" value="EEZ41435"/>
        <property type="gene ID" value="VDA_002467"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0141">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="935289at2"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00014"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004399">
        <property type="term" value="F:histidinol dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06572">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01024">
        <property type="entry name" value="HisD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001692">
        <property type="entry name" value="Histidinol_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022695">
        <property type="entry name" value="Histidinol_DH_monofunct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012131">
        <property type="entry name" value="Hstdl_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21256">
        <property type="entry name" value="PTHR21256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00815">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000099">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00083">
        <property type="entry name" value="HOLDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00069">
        <property type="entry name" value="hisD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00611">
        <property type="entry name" value="HISOL_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="2 5 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 8" id="KW-0520">NAD</keyword>
    <keyword evidence="4 5 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 10" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Proton acceptor" evidence="5 7">
        <location>
            <position position="323"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5 7">
        <location>
            <position position="324"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 8">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 8">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 8">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 9">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 9 10">
        <location>
            <position position="256"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 9 10">
        <location>
            <position position="259"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 9">
        <location>
            <position position="324"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 9 10">
        <location>
            <position position="357"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 9">
        <location>
            <position position="411"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 9 10">
        <location>
            <position position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR000099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000099-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000099-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000099-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000099-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ41435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="431" mass="46363" checksum="E43E8EA951C3BE56" modified="2010-01-19" version="1">MKTVYWQQYSEQEQQQLLTRPAITDGAAIKAKVAQVINSVRETGDQALFELTEKFDQQTLKQLAITSKQIQQASDRLSESMKQALNQAYDNIALFHQAQKAKPVIVETQSGVICEQITRPINAVGLYIPGGSAPLPSTVLMLGIPAQIAGCKQVVLCSPPPISDEILYVAQLCNITTIFQIGGAQAIAAMAYGTESVPKVDKIFGPGNAYVTEAKRQVSNDFQGAAMDMPAGPSEVLVIADHSANPAFIAADLLSQAEHGPDSQVVLVTPDETIAQQTAIEIEKQLAELSRSTIADKALTSSLLIVAQDIEQCIAISNQYGPEHLIVQTEDPRALLSKLDNAGSIFLGLWSPESVGDYASGTNHVLPTYGYTKTYSSLGLADFSKRMTVQQLSAEGLMALAPTVTTIADAEGLDAHKRAVTIRVEQYQTQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYV5</accession>
    <name>D0YYV5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Histidinol-phosphate aminotransferase</fullName>
            <ecNumber evidence="6">2.6.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Imidazole acetol-phosphate transaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">hisC</name>
        <name evidence="8" type="ORF">VDA_002468</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>2-oxoglutarate + L-histidinol phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:23744"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57766"/>
            <dbReference type="ChEBI" id="CHEBI:57980"/>
            <dbReference type="EC" id="2.6.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 6">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 6">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 7/9.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 6">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.9" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002468"/>
    <dbReference type="EnsemblBacteria" id="EEZ41436">
        <property type="protein sequence ID" value="EEZ41436"/>
        <property type="gene ID" value="VDA_002468"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0079">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00012"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004400">
        <property type="term" value="F:histidinol-phosphate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01023">
        <property type="entry name" value="HisC_aminotrans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001917">
        <property type="entry name" value="Aminotrans_II_pyridoxalP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005861">
        <property type="entry name" value="HisP_aminotrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01141">
        <property type="entry name" value="hisC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00599">
        <property type="entry name" value="AA_TRANSFER_CLASS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5 6 8" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="6" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="7">
        <location>
            <begin position="46"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="6">
        <location>
            <position position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ41436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="348" mass="38616" checksum="348E75517DA7FB86" modified="2010-01-19" version="1">MVKKLARQTVQELTPYQSARRLGGQGDIWLNANESPFANEYNINHTRLNRYSECQPPQLIEAYANYAGVRPEQVLTSRGADEGIELLIRAFCEPNQDAILYCPPTYGMYSISAQTSDVNAIAVPLTKEWQLDLPAIFAQLDRVKLVFVCSPNNPTGNLLAKADIEALLERTQDSALVVVDEAYIDFCSEESVANLLDRYSNLVILRTLSKAFALAGLRCGFTLANPQVIELLLKVIAPYPVPIPVADIAIAALSEAGIARTKFQVLDISANRAYLQAGLGMLPNVRVFDGYGNYLLVQFEDAEPLFKALWDSGIILRRSPIENCIRISIGNRDECEKTLAFIRTQLTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYY4</accession>
    <name>D0YYY4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Zinc ABC transporter permease protein ZnuB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_002497</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the ABC-3 integral membrane protein family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300202.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002497"/>
    <dbReference type="EnsemblBacteria" id="EEZ41465">
        <property type="protein sequence ID" value="EEZ41465"/>
        <property type="gene ID" value="VDA_002497"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1108">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1421296at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037294">
        <property type="entry name" value="ABC_BtuC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001626">
        <property type="entry name" value="ABC_TroCD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30477">
        <property type="entry name" value="PTHR30477"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00950">
        <property type="entry name" value="ABC-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81345">
        <property type="entry name" value="SSF81345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="40"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="85"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="128"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="168"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="213"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="239"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ41465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="261" mass="27863" checksum="1A625B5E70C23519" modified="2010-01-19" version="1">MLEFLLPALAAGIGIALIAGPLGSFVVWRKMAYFGDTLSHASLLGIALGFLFNINLNLALVICCLALAVILVTLQKQKLVATDTLLGILAHSALSLGLVAVSFLDNVRIDLMAYLFGDLLAVTTTDLYWIYGGGVLVLGMLVWLWRPLLSMTINEEMAQVEGINVDLMRLLLMLMVGLVIAVAMKFVGALIITSLLIIPAATARRFARSPEMMACLASIIGAIAVVGGLILSWQYDTPAGPSVVVSAAALFILSQFKKSER</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ08</accession>
    <name>D0YZ08_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 8">Ferrochelatase</fullName>
            <ecNumber evidence="7 8">4.99.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Heme synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Protoheme ferro-lyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">hemH</name>
        <name evidence="9" type="ORF">VDA_002521</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">Catalyzes the ferrous insertion into protoporphyrin IX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>2 H(+) + heme b = Fe(2+) + protoporphyrin IX</text>
            <dbReference type="Rhea" id="RHEA:22584"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:57306"/>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <dbReference type="EC" id="4.99.1.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>Fe-coproporphyrin III + 2 H(+) = coproporphyrin III + Fe(2+)</text>
            <dbReference type="Rhea" id="RHEA:49572"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:68438"/>
            <dbReference type="ChEBI" id="CHEBI:131725"/>
            <dbReference type="EC" id="4.99.1.9"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="6">
            <dbReference type="Rhea" id="RHEA:49574"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="7 8">Porphyrin-containing compound metabolism; protoheme biosynthesis; protoheme from protoporphyrin-IX: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7 8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the ferrochelatase family.</text>
    </comment>
    <dbReference type="EC" id="4.99.1.1" evidence="7 8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002521"/>
    <dbReference type="EnsemblBacteria" id="EEZ41489">
        <property type="protein sequence ID" value="EEZ41489"/>
        <property type="gene ID" value="VDA_002521"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0276">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00252">
        <property type="reaction ID" value="UER00325"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004325">
        <property type="term" value="F:ferrochelatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006783">
        <property type="term" value="P:heme biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00419">
        <property type="entry name" value="Ferrochelatase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03411">
        <property type="entry name" value="Ferrochelatase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00323">
        <property type="entry name" value="Ferrochelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001015">
        <property type="entry name" value="Ferrochelatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019772">
        <property type="entry name" value="Ferrochelatase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033644">
        <property type="entry name" value="Ferrochelatase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033659">
        <property type="entry name" value="Ferrochelatase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11108">
        <property type="entry name" value="PTHR11108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00762">
        <property type="entry name" value="Ferrochelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00109">
        <property type="entry name" value="hemH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00534">
        <property type="entry name" value="FERROCHELATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 7 8" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="2 7 8" id="KW-0408">Iron</keyword>
    <keyword evidence="4 7 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7 8" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="7">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="275"/>
        </location>
        <ligand>
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="324" mass="36731" checksum="7A841F5F56EAFAFC" modified="2010-01-19" version="1">MKDNHKYGVLLANLGTPSEPTTAGVKRFLAEFLHDHRVVDTNRFIWCPILHGIILPTRSPKVAKLYQSIWMDGGSPLMVYSQSQREKLEQQLAVPVELGMTYGEPSLLSGLDKLKQRGCERILVLPLYPQYSATTTAAVFDRIAKDLKQRSDLPELRFVNQYFDHPEYIAALAHSAKTFWQQHGEPDYLLCSYHGIPQRYADNGDPYPEQCHGTTAALAQALDMPREKMSMSFQSIFGREEWVKPYTEGTIRALAQKGVKRLDVMCPAFSVDCLETLEEIASECKEVFLEAGGEAFNLIPCLNDSEDHIHLMMTLVEQYTQGWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ58</accession>
    <name>D0YZ58_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cytochrome c heme lyase subunit CcmH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_002571</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300362.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002571"/>
    <dbReference type="EnsemblBacteria" id="EEZ41539">
        <property type="protein sequence ID" value="EEZ41539"/>
        <property type="gene ID" value="VDA_002571"/>
    </dbReference>
    <dbReference type="GeneID" id="57341188"/>
    <dbReference type="eggNOG" id="COG4235">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1539126at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017560">
        <property type="entry name" value="Cyt_c_biogenesis_CcmI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03142">
        <property type="entry name" value="cytochro_ccmI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0201">Cytochrome c-type biogenesis</keyword>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="90"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="166"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="426" mass="47483" checksum="E3FBD4464F630402" modified="2010-01-19" version="1">MILFWLLTAVIVLFCGAIFVYPMLSHKEVDDVANRDELNKAFYKERVDELAHEAEEGLVEDQQELVAELQQSLLDDIPAQEEEKKSKVSLAMLLPGFILLVGISYGMYFALGGIQKVEAWHNTIDRLPELTQRLMSEQAGEPLSDQDMSDLTLGLRTRLHDHPNDAQGWYLLGRIAMSNRDADTAKSAMKRAYDLDPNNTEYQLGYAQTLMLIDNGNPGSVDYARQLLRHVIKQDHTNMTAMSLLAFDAFEHKEYEQAISYWSMMKALSGSDESRVAMLDRSISRAQAMLNKAAVAPTTTVAKEEAQAKKNDVAADKSVRVTINLGPNVKMPKQGMIMVSVHNASGAPMPIAARRLPLDTKFPLTLTLDDKDNMMPTSKLSDLPDMIIKARIDSDGDVMSKQGDYYGESVLVPLGGSTEMTIDKQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ98</accession>
    <name>D0YZ98_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidoglycan hydrolase FlgJ</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Muramidase FlgJ</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">VDA_002611</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the C-terminal section; belongs to the glycosyl hydrolase 73 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the N-terminal section; belongs to the FlgJ family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300483.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002611"/>
    <dbReference type="EnsemblBacteria" id="EEZ41579">
        <property type="protein sequence ID" value="EEZ41579"/>
        <property type="gene ID" value="VDA_002611"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1705">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3951">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="682655at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004040">
        <property type="term" value="F:amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044780">
        <property type="term" value="P:bacterial-type flagellum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019301">
        <property type="entry name" value="Flagellar_prot_FlgJ_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013377">
        <property type="entry name" value="FlaJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002901">
        <property type="entry name" value="MGlyc_endo_b_GlcNAc-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01832">
        <property type="entry name" value="Glucosaminidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10135">
        <property type="entry name" value="Rod-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00047">
        <property type="entry name" value="LYZ2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02541">
        <property type="entry name" value="flagell_FlgJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1005">Bacterial flagellum biogenesis</keyword>
    <keyword evidence="12" id="KW-0966">Cell projection</keyword>
    <keyword evidence="12" id="KW-0969">Cilium</keyword>
    <keyword evidence="12" id="KW-0282">Flagellum</keyword>
    <keyword evidence="8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0574">Periplasm</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LYZ2" evidence="11">
        <location>
            <begin position="166"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="148"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ41579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="332" mass="36989" checksum="B1920EEE75761F4A" modified="2010-01-19" version="1">MKQIEPGFINDLTNLDRLRAGIGKDKEGSLRQAAQQFESLFTQMLFKSMRNANSAFESDLMSSNNTKFFQQMRDEQMASELSTQGNLGLADMIVKQLGGESDNSLSGKTLPVDKFAVRPISQPSESYYLSADERAKLYQDKYDIEPKSAEQAKTAATPDGVGQLSDMTDRVKTQPEPGRFDSPEGFVAHMKPYAFKASRALGVDPAMLIAQAALETGWGKKVIQNAAGSSHNLFNIKADPRWGGNKVATRTLEYHNGIAVQENAAFRSYHSYQESFDDFVQFLKQNPRYGTALKHTTDPSRFVKEIHNAGYATDPNYSQKVLAVMNKVKTLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ99</accession>
    <name>D0YZ99_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Flagellar P-ring protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Basal body P-ring protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">flgI</name>
        <name evidence="6" type="ORF">VDA_002612</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 5">Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 5">Bacterial flagellum basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the FlgI family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002612"/>
    <dbReference type="EnsemblBacteria" id="EEZ41580">
        <property type="protein sequence ID" value="EEZ41580"/>
        <property type="gene ID" value="VDA_002612"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1706">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009428">
        <property type="term" value="C:bacterial-type flagellum basal body, distal rod, P ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00416">
        <property type="entry name" value="FlgI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001782">
        <property type="entry name" value="Flag_FlgI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30381">
        <property type="entry name" value="PTHR30381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02119">
        <property type="entry name" value="FlgI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01010">
        <property type="entry name" value="FLGPRINGFLGI"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="6" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6" id="KW-0969">Cilium</keyword>
    <keyword evidence="6" id="KW-0282">Flagellum</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="377" mass="39766" checksum="F84304DAC8803FDC" modified="2010-01-19" version="1">MVLNIAYLSQSKSRVLMRLFVFTLSLLLALPTFAARIKDVSEVAGVRSNQLIGYGLVVGLAGSGETTPFTDQSFNTMLKNFGIQLPPGTKPKTKNVAAVVVNATLPAFAKQGQHVDITVSSIGSAKSLHGGTLLQTFLKGLDGKIYAVAQGTLVVGGFSIEGADGSKIVSNTPTVGRISNGATVEQEIASPFGRGDYLTFNLFDSDFTTAQRMADAVNQFLGPDMASAIDATSIRVRAPRDVSQRVAFLSTIENLEFETADSAAKIIVNSRTGTIVVGQHVRLKPAAITHGGMTVTIKENAQVSQPNAFSQGQTVVTPNSDINVTEKNARMFVFQPGVTLDDLVRAVNQVGAGPSDVMAILQALKQAGAIEGQLIII</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZA4</accession>
    <name>D0YZA4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">Basal-body rod modification protein FlgD</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_002617</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5">Required for flagellar hook formation. May act as a scaffolding protein.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the FlgD family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300503.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002617"/>
    <dbReference type="EnsemblBacteria" id="EEZ41585">
        <property type="protein sequence ID" value="EEZ41585"/>
        <property type="gene ID" value="VDA_002617"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1843">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="709873at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044781">
        <property type="term" value="P:bacterial-type flagellum organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005648">
        <property type="entry name" value="FlgD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025965">
        <property type="entry name" value="FlgD_Ig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025963">
        <property type="entry name" value="FLgD_Tudor"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03963">
        <property type="entry name" value="FlgD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13860">
        <property type="entry name" value="FlgD_ig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13861">
        <property type="entry name" value="FLgD_tudor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-1005">Bacterial flagellum biogenesis</keyword>
    <keyword evidence="9" id="KW-0966">Cell projection</keyword>
    <keyword evidence="9" id="KW-0969">Cilium</keyword>
    <keyword evidence="9" id="KW-0282">Flagellum</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FLgD_tudor" evidence="8">
        <location>
            <begin position="95"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="FlgD_ig" evidence="7">
        <location>
            <begin position="118"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="243" mass="25978" checksum="6BA53D895C0AF598" modified="2010-01-19" version="1">MTSINGNAGNNLSYLDQLKGMHDKKVQQEQKTTGQNALKQEDFLSLLTKQLAQQDPFKPVSNDQMIAQMASFATVDGITKMNDQFGVLNTALTSNQALQASSLVGLDVLIPSATAMKTQDGAMSGVVRVNQGVDNAILRVENEKGELVKTVSLGTQAPGEHPFSWDGKDDNGNSLPHGKYRFAVSGTSGGKNQEFEVFTHANVNSVLMGNQDGQVMLNLAGFSSPYKLTDVLQVGQATEKGNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZB2</accession>
    <name>D0YZB2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AAA_23 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002625</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300526.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002625"/>
    <dbReference type="EnsemblBacteria" id="EEZ41593">
        <property type="protein sequence ID" value="EEZ41593"/>
        <property type="gene ID" value="VDA_002625"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0419">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="886955at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022205">
        <property type="entry name" value="DUF3732"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038729">
        <property type="entry name" value="Rad50/SbcC_AAA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13476">
        <property type="entry name" value="AAA_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12532">
        <property type="entry name" value="DUF3732"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_23" evidence="2">
        <location>
            <begin position="20"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="201"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="384"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="649" mass="75746" checksum="6814825F9EBDC8A4" modified="2010-01-19" version="1">MKAFLRNIILIGHDGTVKDLGFERGLNIITGDSKTGKSALIEIVDYCLFSKRSTIPVGIVTDFTDIFCCVFEHNNKKIVIGRSNRQPTKCYFAVEYSVDFIADNIINANYFKSKKTRSRLEVQKDFEEHLGLSVEDTSLTENDYNLNKGKVSIRNATSLFFQHQNLIANKHSLFCRFDNFIKSRSVIDQFPIFMGWVDSRYYRLKKRSEELEKQIKKIDKEEKKTQLDIQEKREKLLIPIREYYRILNLKFLDEDASLDKLKYLARNLPFVPLNAEQNVDFNKQLNSLEKKKDKELTSLYECNQLISLIKSNEEESIDYSNSMERLKEISQDEFESKHNVSCPLCNAPVSNVVARVEEVKHSRMLLLDELSRINSYKQDSSKSLNSLLLKRDKQKQVIANIENEMKQLRKLYKVKNNLDIRDSLNIIRGRIESSLEIFIEGQSSEKANHYLSELREELEICDEQIRGYGLEHKFSEANALINQTMNELKKDLDFEDDLRDGEMKFKTEDFTFTYYFKKQEILLSEMGSGANWLACHLAVFLSILKLTSSSHSVIPAFLFLDQPSQVYFPKVTRRFSSINKEELSNEDGVDEDIKQVINIFKVIERFLDKLEEDPNVGFKPQIIVLEHADQPEFNKYIRYRWSSNGSKLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZF8</accession>
    <name>D0YZF8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Flagellar motor rotation protein MotA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">VDA_002671</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MotA family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300665.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002671"/>
    <dbReference type="EnsemblBacteria" id="EEZ41639">
        <property type="protein sequence ID" value="EEZ41639"/>
        <property type="gene ID" value="VDA_002671"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1291">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="897037at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097588">
        <property type="term" value="P:archaeal or bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000540">
        <property type="entry name" value="Flag_MotA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002898">
        <property type="entry name" value="MotA_ExbB_proton_chnl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01618">
        <property type="entry name" value="MotA_ExbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01307">
        <property type="entry name" value="MOTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0966">Cell projection</keyword>
    <keyword evidence="11" id="KW-0969">Cilium</keyword>
    <keyword evidence="6" id="KW-0283">Flagellar rotation</keyword>
    <keyword evidence="11" id="KW-0282">Flagellum</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="7"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="140"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="178"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="MotA_ExbB" evidence="10">
        <location>
            <begin position="99"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ41639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="253" mass="27422" checksum="6D6BD4C67380F37C" modified="2010-01-19" version="1">MDLATLIGMLGAFAFIVMAMLLGGSLGMFFDVPSVLIVFGGTTFVVLMKYSIGQFLGATKIAAKAFMYKTDNPEELIAKIVEMADAARKGGFLALEEMEIDNPFLRKGIDLLVDGHDADVVRATLQKDISLTHERHEQGIGIFTSFGDVGPAMGMIGTLIGLVAMLSNMDDPKSIGPAMAVALLTTLYGSILANMVALPIADKLSLRKDQERLNRRLILDGVLAIQDGQNPRVIDGYLKNYLHEKKRVTAMDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZJ9</accession>
    <name>D0YZJ9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">Iron-sulfur cluster assembly scaffold protein IscU</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_002712</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the NifU family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300790.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002712"/>
    <dbReference type="EnsemblBacteria" id="EEZ41680">
        <property type="protein sequence ID" value="EEZ41680"/>
        <property type="gene ID" value="VDA_002712"/>
    </dbReference>
    <dbReference type="GeneID" id="57341016"/>
    <dbReference type="eggNOG" id="COG0822">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1793654at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06664">
        <property type="entry name" value="IscU_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011339">
        <property type="entry name" value="ISC_FeS_clus_asmbl_IscU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002871">
        <property type="entry name" value="NIF_FeS_clus_asmbl_NifU_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10093">
        <property type="entry name" value="PTHR10093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01592">
        <property type="entry name" value="NifU_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01999">
        <property type="entry name" value="iscU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NifU_N" evidence="4">
        <location>
            <begin position="2"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="128" mass="13686" checksum="79D70D4B22669500" modified="2010-01-19" version="1">MAYSEKVIDHYENPRNVGSFDKGDKNVGSGMVGAPACGDVMQLQIRVSDGGIIEDAKFKTYGCGSAIASSSLITEWVKGKTLDEAASIKNAAIAEELELPPVKVHCSILAEDAIKAAISDYKKKHEQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZL8</accession>
    <name>D0YZL8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Phosphate transport system permease protein PstA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_002731</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell inner membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300846.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002731"/>
    <dbReference type="EnsemblBacteria" id="EEZ41699">
        <property type="protein sequence ID" value="EEZ41699"/>
        <property type="gene ID" value="VDA_002731"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0581">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1763210at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:inorganic phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035435">
        <property type="term" value="P:phosphate ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005672">
        <property type="entry name" value="Phosphate_PstA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00974">
        <property type="entry name" value="3a0107s02c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="293"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="334"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="380"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="433"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="510"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="297"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="154"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ41699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="545" mass="61031" checksum="C9B2D4E3E6C31622" modified="2010-01-19" version="1">MIKWFKSGAPWIWLTAGSVSVSLLAVLGLLLLIGWKGLSYFWPDSVYRFDITSNGKTHSLLGEIYDQQVISRQQLLEAGVQLDPANLDDITRYVIKVGNREQNGSDFVTVLSTHIVQQQLADNVVVVDRDKNGKFYGYPVAIYEGKVELPFHDYLQLKEKTLQLRHDLEQLQQVEIANVNWQLEQLRIQHRKAELKGQAEPDKIQQYERQRRQLELEYKQMEGHLFSLQNQLADSGIIVRNSQGQQVKLPMDQVLDVWQPNNLTLIEKIAHWGHQVGKFLSEEPREANTEGGVFPAIFGTVFMVLLMSIIVTPLGVMAAVYLHEYAKKNAFTKVIRIAVINLAGVPSIVYGVFGLGFFVYMVGGTIDDLFFSAQLPTPTFGTPGVLWSALTLAILTLPVVIVSTEEGLARIPNSVRNGSLALGATQSETLWRIVLPMASPAIMTGLILAVARAAGEVAPLMLVGVVKMAPTLPVDLHFPYVHLDRKFMHLGYHIYDVAFQSPNVEAARPLVYATSFLLVTVIISLNLTAIGIRNYLREKYRTLEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZR9</accession>
    <name>D0YZR9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Protein ea31</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002782</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300991.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002782"/>
    <dbReference type="EnsemblBacteria" id="EEZ41750">
        <property type="protein sequence ID" value="EEZ41750"/>
        <property type="gene ID" value="VDA_002782"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1403">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1843957at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00085">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="284" mass="32355" checksum="F041C502098CE514" modified="2010-01-19" version="1">MLKLKRPVSSYPEMLSLCRSGITGNVGLRQNVTDVSRLLEQKAEEYEASATTGELYTIDPLPRPQDDPVVIGCLKKSDLVKLYDYYVVGKRKPARAVYDALMVAANDKCPFCGGIGRPRNLDHYLPKAHYPQFSIVPVNLVPSCRDCNMDGKGQAFASAEKEQVLQPYLDDDRFFNEQWLYARYHPGENDEPGVIEYFVSPPEYWEDDQKKRVDKHFKDFDLALRFSKEAGPRLVSLMAQYNALLVAPVDKETSKNIIFQTVIDASSFINHWERVMCLALMDTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z008</accession>
    <name>D0Z008_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA1(Val) (adenine(37)-N6)-methyltransferase</fullName>
            <ecNumber evidence="3">2.1.1.223</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">tRNA m6A37 methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_002871</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>adenosine(37) in tRNA1(Val) + S-adenosyl-L-methionine = H(+) + N(6)-methyladenosine(37) in tRNA1(Val) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:43160"/>
            <dbReference type="Rhea" id="RHEA-COMP:10369"/>
            <dbReference type="Rhea" id="RHEA-COMP:10370"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74449"/>
            <dbReference type="EC" id="2.1.1.223"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.223" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301249.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002871"/>
    <dbReference type="EnsemblBacteria" id="EEZ41839">
        <property type="protein sequence ID" value="EEZ41839"/>
        <property type="gene ID" value="VDA_002871"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4123">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1027015at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016430">
        <property type="term" value="F:tRNA (adenine-N6-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01872">
        <property type="entry name" value="tRNA_methyltr_YfiC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007848">
        <property type="entry name" value="Small_mtfrase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022882">
        <property type="entry name" value="tRNA_adenine-N6_MeTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05175">
        <property type="entry name" value="MTS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="1 3 5" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="MTS" evidence="4">
        <location>
            <begin position="36"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="237" mass="25693" checksum="C39DB6D6B42B46BF" modified="2010-01-19" version="1">MSSGFTLKQFHVNHGGCGMPVSTDGILLGAWAKLEQTQPILDIGTGSGLLALMAAQRTGDASITAIELDPTAALVAKDNFGHSPWSARLSCIEANLIHWFPTISKQTFGSIVCNPPYFNFGQQAQRGQRAQARHTDTLSHSALLQALKHLLADNGQASLILPTYEGEQLIKAAADYGLSCCRLCRVQSTAKKPIFRLLMAFTASENRNCEETTLCIHDGNGYSAEFIALTQSFYLNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z044</accession>
    <name>D0Z044_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">(GlcNAc)2 ABC transporter permease component 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_002907</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301317.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002907"/>
    <dbReference type="EnsemblBacteria" id="EEZ41875">
        <property type="protein sequence ID" value="EEZ41875"/>
        <property type="gene ID" value="VDA_002907"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1173">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1734230at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="107"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="217"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="277"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="103"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="321"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="341" mass="36830" checksum="223232A4F2C5A090" modified="2010-01-19" version="1">MKALFKLLTGNPKALFGLGILTVFIFGAIFAPLITSYAPDKRTGNPHEYPAFVVKAAQNNPDGWVAENLATSKRTLLLSKKADHVLGTSRMGRDIWSQLVYGTRTSLAVGFGAGIMVCFLATIIGVSAGYFGGRIDDVLTAAMNIMLVMPQLPLLFVIAAFIGQAGPMTIALVIAVTSWAWGARVVRAQTLSLREKEFVKAAEVLGESSWRIILVEILPNLISIVGASFIGSVMLAIMTEATLSFLGLGDPNTVSWGIMLYNVQTSSSMLVGAWWEVLAPCLALTFVAIGLAMLNFAVDEIANPQLRSHKGMRRWKNMANQNKQENKAVEAPQPALEMGEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z046</accession>
    <name>D0Z046_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">(GlcNAc)2 ABC transporter ATP-binding component 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_002909</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301321.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002909"/>
    <dbReference type="EnsemblBacteria" id="EEZ41877">
        <property type="protein sequence ID" value="EEZ41877"/>
        <property type="gene ID" value="VDA_002909"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4608">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1303270at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01727">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="12"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="53"/>
            <end position="60"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="333" mass="37337" checksum="2506C820A8DC4D31" modified="2010-01-19" version="1">MSTPAPIGNPILEGKNLVKDFPVNSNSLKKSMMRAINDVSFKMYKSRGLSVVGESGSGKSTTAKMIAKMYAPTAGHIEYYGRDIAEIVKRDDMMKYREGIQMVWQDPFGSLNPTHTIFHHIARPLLIHKKVTPGNKKELEERVYDLLEQVGLIPPKETAAKFPHQLSGGQRQRVNLARNIAVGAEVVLADEPTSMLDVSIRAGVLNLMEEMKFEREMALLYITHDIATARYIAEDLAVMYVGHMVEWGDTEDIIHNPQHPYTQLLVSAVPDPKKSIHEKLKGNKGEIPLWTPESVGCPFAGRCTHATAKCREQLPSVTKLSENHFVRCYLFEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z062</accession>
    <name>D0Z062_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Arginine/ornithine antiporter ArcD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_002925</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301368.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002925"/>
    <dbReference type="EnsemblBacteria" id="EEZ41893">
        <property type="protein sequence ID" value="EEZ41893"/>
        <property type="gene ID" value="VDA_002925"/>
    </dbReference>
    <dbReference type="GeneID" id="57340772"/>
    <dbReference type="eggNOG" id="COG1288">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="350103at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018385">
        <property type="entry name" value="C4_dicarb_anaerob_car-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018387">
        <property type="entry name" value="YcgA/YfcC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43652:SF6">
        <property type="entry name" value="PTHR43652:SF6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03606">
        <property type="entry name" value="DcuC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="96"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="138"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="179"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="218"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="280"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="306"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="339"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="394"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="434"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="462"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="485" mass="52042" checksum="8721A607D78CA5AF" modified="2010-01-19" version="1">MTTETAPKDKKEEKGGFFANFKFPSAYTILFALIAVVALLTWIVPAGQYNRVMNEELGKEVPVTGTYHAVESNPQGVVDVLLAPIDGFYDHDSYEAAAIDVSLFILIIGGFLGLVTKTGAIDAGIERVTARLQGKEELMIPILMALFAAGGTIYGMAEESLPFYTLLVPVMMAARFDPVVAAATVLLGAGIGTLGSTINPFATVIAANAAGIPFTDGIALRVAILVIGWVICVGYVMRYAKMVRSDHTKSIVFDKYEENKAHFLGNQTGELLEFTTTRKIILTIFALSFGIMIYGVSVLGWWMAQISAMFLGSAILIGLIARMSEEDFTTSFIDGARDLLGVALIIGIARGIVVIMDRGMITDTILNSAEHIVSGLSSIVFINVMYWLEVLLSFLVPSSSGLAVLTMPIMAPLADFAGVSRDLVVTAYQSASGIVNMMTPTSAVVMGGLAIARVPYVRWVKWVMPLLGILTVLIMVMLSIGAMMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z086</accession>
    <name>D0Z086_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 14">Undecaprenyl-diphosphatase</fullName>
            <ecNumber evidence="4 14">3.6.1.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13 14">Bacitracin resistance protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12 14">Undecaprenyl pyrophosphate phosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">uppP</name>
        <name evidence="15" type="ORF">VDA_002949</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>di-trans,octa-cis-undecaprenyl diphosphate + H2O = di-trans,octa-cis-undecaprenyl phosphate + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:28094"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58405"/>
            <dbReference type="ChEBI" id="CHEBI:60392"/>
            <dbReference type="EC" id="3.6.1.27"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="14">Cell membrane</location>
            <topology evidence="14">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="14">Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the UppP family.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.27" evidence="4 14"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301407.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002949"/>
    <dbReference type="EnsemblBacteria" id="EEZ41917">
        <property type="protein sequence ID" value="EEZ41917"/>
        <property type="gene ID" value="VDA_002949"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1968">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1826154at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050380">
        <property type="term" value="F:undecaprenyl-diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016311">
        <property type="term" value="P:dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01006">
        <property type="entry name" value="Undec_diphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003824">
        <property type="entry name" value="UppP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30622">
        <property type="entry name" value="PTHR30622"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02673">
        <property type="entry name" value="BacA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00753">
        <property type="entry name" value="undec_PP_bacA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 14" id="KW-0046">Antibiotic resistance</keyword>
    <keyword evidence="6 14" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="14" id="KW-0133">Cell shape</keyword>
    <keyword evidence="14" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="8 14 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="85"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="109"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="187"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="217"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="250"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00032932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEZ41917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="267" mass="29179" checksum="82E498446A1BE6D2" modified="2010-01-19" version="1">MSHFEAFMLALIQGLTEFLPISSSAHLILPSEVLGWPDQGLAFDVAVHVGTLAAVILYFRKEVVSLLSAWLNSIFKQQHNKESKLAWMIVIATIPACIFGLFMKDIIELYLRSAWVIACTTVIFGLLLWWVDKHSALNKDEYSAGWKQSLFIGLSQAMAMIPGTSRSGATMTAALYLGFTREAAARFSFLMSIPIILLAGGYLGLKLVTSGQPVDLGALGIGISVSFVSAYACIHVFLKLVTRLGMTPFVIYRLLLGIGLIAFLLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0C9</accession>
    <name>D0Z0C9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Fructose-1,6-bisphosphatase class 1</fullName>
            <shortName evidence="7">FBPase class 1</shortName>
            <ecNumber evidence="7">3.1.3.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">fbp</name>
        <name evidence="11" type="ORF">VDA_002992</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>beta-D-fructose 1,6-bisphosphate + H2O = beta-D-fructose 6-phosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:11064"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="EC" id="3.1.3.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="7">Binds 2 magnesium ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7 8">Belongs to the FBPase class 1 family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.11" evidence="7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301498.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002992"/>
    <dbReference type="EnsemblBacteria" id="EEZ41960">
        <property type="protein sequence ID" value="EEZ41960"/>
        <property type="gene ID" value="VDA_002992"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0158">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="945770at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042132">
        <property type="term" value="F:fructose 1,6-bisphosphate 1-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016051">
        <property type="term" value="P:carbohydrate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00354">
        <property type="entry name" value="FBPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01855">
        <property type="entry name" value="FBPase_class1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044015">
        <property type="entry name" value="FBPase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000146">
        <property type="entry name" value="FBPase_class-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033391">
        <property type="entry name" value="FBPase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028343">
        <property type="entry name" value="FBPtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020548">
        <property type="entry name" value="Fructose_bisphosphatase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11556">
        <property type="entry name" value="PTHR11556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00316">
        <property type="entry name" value="FBPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18913">
        <property type="entry name" value="FBPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500210">
        <property type="entry name" value="FBPtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000904">
        <property type="entry name" value="FBPtase_SBPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00115">
        <property type="entry name" value="F16BPHPHTASE"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00124">
        <property type="entry name" value="FBPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FBPase" evidence="9">
        <location>
            <begin position="6"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="FBPase_C" evidence="10">
        <location>
            <begin position="201"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="118"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="262"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="115"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="244"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="274"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="280"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF18913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ41960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="336" mass="37330" checksum="482EC7E29797443B" modified="2010-01-19" version="1">MSDIRTLGEFIVEKQNDFPHASGELSSLLGSIKLAAKIVNREINKAGLVDITGAVGAENIQGEQQQKLDVYANDKFKAALEARDQVCGVASEEEDEAVAFNKELNRNAKYVVLMDPLDGSSNIDVNVSVGTIFSIYRRVSPIGTPPTQEDFLQPGHQQVAAGYVIYGSSTMLVYTTGNGVHGFTYDPSLGVFCLSHENMQIPVNGTIYSINEGNYIRFPQGIKQYIKFCQENTPEHNRPYTSRYIGSLVADFHRNLLKGGIYLYPSTLTHPNGKLRLLYECNPMAFIVEQAGGCASDGINRILDLKPQELHQRVPFFVGSKNMVKQVEDYLERYCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0H6</accession>
    <name>D0Z0H6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_003040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ42007">
        <property type="protein sequence ID" value="EEZ42007"/>
        <property type="gene ID" value="VDA_003040"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5033U7A">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1665749at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ42007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="193" mass="21378" checksum="5E1E6D0F891A0748" modified="2010-01-19" version="1">MTNHHHNHCCGHHGHDNHDHNCSVSLQLGQVVEQHPFQFDDGAMIELCRRDLGNEIFIGLGGLTRAEIETLTTAPVELGLLATEAGGCLIVVKIGDIVLDVQFNAAAIPDEHYQAEINSQVTLLALDTHTKELKVKRDIELTNELVAQLTRLTARQRTEETNQINAENAHLLNTLTPEQLAEKITLVELANHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0H8</accession>
    <name>D0Z0H8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Phosphatidylserine decarboxylase proenzyme</fullName>
            <ecNumber evidence="11">4.1.1.65</ecNumber>
        </recommendedName>
        <component>
            <recommendedName>
                <fullName evidence="11">Phosphatidylserine decarboxylase alpha chain</fullName>
            </recommendedName>
        </component>
        <component>
            <recommendedName>
                <fullName evidence="11">Phosphatidylserine decarboxylase beta chain</fullName>
            </recommendedName>
        </component>
    </protein>
    <gene>
        <name evidence="11" type="primary">psd</name>
        <name evidence="12" type="ORF">VDA_003042</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-L-serine + H(+) = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CO2</text>
            <dbReference type="Rhea" id="RHEA:20828"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57262"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
            <dbReference type="EC" id="4.1.1.65"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </cofactor>
        <text evidence="11">Binds 1 pyruvoyl group covalently per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="11">Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cell membrane</location>
            <topology evidence="11">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="11">Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.65" evidence="11"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301673.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003042"/>
    <dbReference type="EnsemblBacteria" id="EEZ42009">
        <property type="protein sequence ID" value="EEZ42009"/>
        <property type="gene ID" value="VDA_003042"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0688">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="891720at2"/>
    <dbReference type="UniPathway" id="UPA00558">
        <property type="reaction ID" value="UER00616"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00705"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004609">
        <property type="term" value="F:phosphatidylserine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006646">
        <property type="term" value="P:phosphatidylethanolamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00662">
        <property type="entry name" value="PS_decarb_PSD_B_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003817">
        <property type="entry name" value="PS_Dcarbxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033177">
        <property type="entry name" value="PSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033178">
        <property type="entry name" value="PSD_type1_pro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10067">
        <property type="entry name" value="PTHR10067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02666">
        <property type="entry name" value="PS_Dcarbxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00163">
        <property type="entry name" value="PS_decarb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 11" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="3 11" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5 11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 11 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 11" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="9 11" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="10 11" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0865">Zymogen</keyword>
    <feature type="chain" id="PRO_5023549616" description="Phosphatidylserine decarboxylase beta chain" evidence="11">
        <location>
            <begin position="1"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023549615" description="Phosphatidylserine decarboxylase alpha chain" evidence="11">
        <location>
            <begin position="253"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system; for autoendoproteolytic cleavage activity" evidence="11">
        <location>
            <position position="90"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system; for autoendoproteolytic cleavage activity" evidence="11">
        <location>
            <position position="147"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system; for autoendoproteolytic cleavage activity" evidence="11">
        <location>
            <position position="253"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity" evidence="11">
        <location>
            <position position="253"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage (non-hydrolytic); by autocatalysis" evidence="11">
        <location>
            <begin position="252"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="modified residue" description="Pyruvic acid (Ser); by autocatalysis" evidence="11">
        <location>
            <position position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ42009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="293" mass="32533" checksum="757080D6C827B044" modified="2010-01-19" version="1">MLDNIKIGLQYCAPKHALTRLAGKLASWKGGKLTTAVIRWFIKQYKIEMAEARNPDPAAYATFNDFFVRELKDGARPINDDANIVCFPADACVSQLGPIKEGRLFQAKGHYFDTRELVGGDNELAERFTDGSFATLYLSPRDYHRVHMPCDGTLRQMIYIPGDLFSVNPLTAENVPNLFARNERVVCVFDTDFGPMVQILVGATIVGSIETVWAGTVTPPTGPSIRRWDYAPTGETSVVLKKGQEMGRFKLGSTVINLFSKDAVHFVESLQSGTVTRMGQPYAEINQQSESEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0K0</accession>
    <name>D0Z0K0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative transcriptional regulator LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_003064</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301733.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003064"/>
    <dbReference type="EnsemblBacteria" id="EEZ42031">
        <property type="protein sequence ID" value="EEZ42031"/>
        <property type="gene ID" value="VDA_003064"/>
    </dbReference>
    <dbReference type="GeneID" id="57340465"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1661500at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="8"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ42031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="305" mass="34443" checksum="8CCAD8AA17C90D55" modified="2010-01-19" version="1">MQRCKNGMKLDDLRTLIAIAKHGSFRSAAQALDIPPTTLSRRLQRLEDTLGSQLVLRDSRNVALTPLGQNYVERCEPLIKELEVATLELDDISHSEPRGALRISAPVGLLTYKLMPLFNEFLSLYPEVTLSLNHLSNQHHDYSPEQYDVVFRVGHQPDSSFAAATIGQSQRILVASPCYLAKNDTPQHPNDLYQHERLATVPEFEWALRHDDIQQHPDTLWVNSPVRLAIADLNSVKQAAIAGLGIACLPNYVVADALQRGALKTLMTDWYSPSRPIYMLYQRLEYTPAHISCFIDFMRKGLTEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0Q9</accession>
    <name>D0Z0Q9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">General secretion pathway protein C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_003123</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GSP C family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301933.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003123"/>
    <dbReference type="EnsemblBacteria" id="EEZ42090">
        <property type="protein sequence ID" value="EEZ42090"/>
        <property type="gene ID" value="VDA_003123"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3031">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1597080at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024961">
        <property type="entry name" value="T2SS_GspC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001639">
        <property type="entry name" value="T2SS_protein-GspC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11356">
        <property type="entry name" value="T2SSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01713">
        <property type="entry name" value="typeII_sec_gspC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSC" evidence="9">
        <location>
            <begin position="26"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF11356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ42090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="293" mass="32266" checksum="48664731F8BFDB4F" modified="2010-01-19" version="1">MVVFKQLNQFKMHSPMPIAKVAQIVTLLLVIWFGWILGRLVWTVIQPAETVTSWQPSQTQSVGQQQKFPVADLIAMNLFGLYQQSAQPVATPVKQDAPETRLNLTLNGVVASSNPEKALAIITNQGKQNTYGLNEAIKGTRATLQAVYADRVIIRNSGSDETLMLDGVKFSKTSTATQPTAPVTTQSSSSSGELEKIKAEIMKNPQNLFSYIRLSQVKNDGKLMGYRVNPGKNKILFDEVGLEPNDLAVTLNGNDLTDPTVMTKLWSELSQASSFTLGVERDGQLHDIYIELQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z113</accession>
    <name>D0Z113_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative transcriptional regulator DeoR family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_003227</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302220.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003227"/>
    <dbReference type="EnsemblBacteria" id="EEZ42194">
        <property type="protein sequence ID" value="EEZ42194"/>
        <property type="gene ID" value="VDA_003227"/>
    </dbReference>
    <dbReference type="GeneID" id="57340366"/>
    <dbReference type="eggNOG" id="COG1349">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1629121at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014036">
        <property type="entry name" value="DeoR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001034">
        <property type="entry name" value="DeoR_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018356">
        <property type="entry name" value="Tscrpt_reg_HTH_DeoR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00455">
        <property type="entry name" value="DeoRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08220">
        <property type="entry name" value="HTH_DeoR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00037">
        <property type="entry name" value="HTHLACR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00420">
        <property type="entry name" value="HTH_DEOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00894">
        <property type="entry name" value="HTH_DEOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51000">
        <property type="entry name" value="HTH_DEOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH deoR-type" evidence="4">
        <location>
            <begin position="6"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ42194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="255" mass="27997" checksum="3A02CAE8332A3896" modified="2010-01-19" version="1">MSKRNTQQRRHAIVTLVNEQGEVSVDKLAEQFATSEVTIRKDLAALENNGLLLRRYGGAIAMPSEIMTDDSEDKVSVQKVAIAQEAEKRIRDHNRIIVDSGSTTAALISLLGRKQGLIVMTNSLQVANALNELENEPTLLMTGGTWDPHSESFQGQVAESVLRSYDFDQLFIGADGIDIARGTTTFNELIGLSRVMAEVSREVVVMVESSKIGRKIPNLEIPWSNINTVITDSGLSDTAKQQIEQHGVQVIRAPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z171</accession>
    <name>D0Z171_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Sec-independent protein translocase protein TatC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">tatC</name>
        <name evidence="6" type="ORF">VDA_003285</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TatC family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302385.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003285"/>
    <dbReference type="EnsemblBacteria" id="EEZ42252">
        <property type="protein sequence ID" value="EEZ42252"/>
        <property type="gene ID" value="VDA_003285"/>
    </dbReference>
    <dbReference type="GeneID" id="57340282"/>
    <dbReference type="eggNOG" id="COG0805">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1848013at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033281">
        <property type="term" value="C:TAT protein transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043953">
        <property type="term" value="P:protein transport by the Tat complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00902">
        <property type="entry name" value="TatC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019820">
        <property type="entry name" value="Sec-indep_translocase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002033">
        <property type="entry name" value="TatC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30371">
        <property type="entry name" value="PTHR30371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00902">
        <property type="entry name" value="TatC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01840">
        <property type="entry name" value="TATCFAMILY"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00945">
        <property type="entry name" value="tatC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01218">
        <property type="entry name" value="TATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0811">Translocation</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="75"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="117"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="158"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="196"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="220"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ42252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="251" mass="28174" checksum="B5287DA681D4985B" modified="2010-01-19" version="1">MSTVEETQPLFSHLLELRNRILRSLLSVLVVFLCLVWFSNDIYTFLSAPLVERMPAGATMIATDVASPFFAPIKLTLVTSVFIAVPMILYQVWAFVAPGLYKHERKMIVPLLVSSSVLFYVGVAFAYFVVFPLVFKFFTSTAPAGVQVATDIMSYLDFVLALFMAFGIAFEVPVAIILLCWTGATDPQSLREKRPYIIVAAFVVGMLLTPPDIISQTLLAVPMCLLFEVGLFFSRYYVRDNDEAEEEQYDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1E3</accession>
    <name>D0Z1E3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Capsular polysaccharide biosynthesis protein BcbE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_003357</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302562.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003357"/>
    <dbReference type="EnsemblBacteria" id="EEZ42324">
        <property type="protein sequence ID" value="EEZ42324"/>
        <property type="gene ID" value="VDA_003357"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1209">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1557977at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016873">
        <property type="entry name" value="Caps_polysacc_synth_BcbE_prd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028162">
        <property type="entry name" value="BcbE_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ42324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="242" mass="27987" checksum="2B86B9FDE7F74DF6" modified="2010-01-19" version="1">MIVIPMAGLSSRFYKAGYTQPKYMLQAHGKTLFDHALNSFEQYFATEPFLFIVRDIDGTVDFVKQSVEKLGIQQSHIYVLQEPTRGQAETVYLGLNSVPEYQGSITIFNIDTFRPNFHYPEELKLWDGYLEVFQGEGDNWSFAKAESPLSTKVIKTAEKEPISDLCSTGLYYFSDSAFFIESYQQYIQQPVETWAKGELYIAPLYNYLIQQNKNIHYHLIQRDDVIFCGVPDEYTAFLETSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1E6</accession>
    <name>D0Z1E6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative Lex2B protein (Lipooligosaccharide 5G8 epitopebiosynthesis-associated protein)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_003360</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302568.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003360"/>
    <dbReference type="EnsemblBacteria" id="EEZ42327">
        <property type="protein sequence ID" value="EEZ42327"/>
        <property type="gene ID" value="VDA_003360"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3306">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1763104at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06532">
        <property type="entry name" value="Glyco_transf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002654">
        <property type="entry name" value="Glyco_trans_25"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01755">
        <property type="entry name" value="Glyco_transf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ42327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="249" mass="29031" checksum="EFB09DFB5FD289EA" modified="2010-01-19" version="1">MIDIFVINIPSSVERKENITQQLVKLNLDFKLFEAVNGHKDSSPLFNLYDEALSQQYRGKSLSKGQLGCYASHYLLWQKCVEINKPIIILEDDALIYSEPFLDIVENASKLAEHFECIRLFDNKRKTFRHAKEYPLPHTAVHKFSKGHMSATGYFLTPTGAKKFLAHSQAWYLAVDIYMDRFWINDVNVHGTVPACLSNDPKFDSDIGYGAKPKRDLYCRLKREVFNLAELFRREYHNACYRIRMKRKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1M0</accession>
    <name>D0Z1M0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5 7">30S ribosomal protein S12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpsL</name>
        <name evidence="8" type="ORF">VDA_003434</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5 7">Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.</text>
    </comment>
    <comment type="function">
        <text evidence="1 5 7">With S4 and S5 plays an important role in translational accuracy.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 7">Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5 6">Belongs to the universal ribosomal protein uS12 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_004399892.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="SMR" id="D0Z1M0"/>
    <dbReference type="STRING" id="675817.VDA_003434"/>
    <dbReference type="EnsemblBacteria" id="EEZ42401">
        <property type="protein sequence ID" value="EEZ42401"/>
        <property type="gene ID" value="VDA_003434"/>
    </dbReference>
    <dbReference type="GeneID" id="61877535"/>
    <dbReference type="GeneID" id="67376031"/>
    <dbReference type="eggNOG" id="COG0048">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1707228at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03368">
        <property type="entry name" value="Ribosomal_S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00403_B">
        <property type="entry name" value="Ribosomal_S12_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006032">
        <property type="entry name" value="Ribosomal_S12/S23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005679">
        <property type="entry name" value="Ribosomal_S12_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11652">
        <property type="entry name" value="PTHR11652"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00164">
        <property type="entry name" value="Ribosom_S12_S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002133">
        <property type="entry name" value="Ribosomal_S12/S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01034">
        <property type="entry name" value="RIBOSOMALS12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00981">
        <property type="entry name" value="rpsL_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00055">
        <property type="entry name" value="RIBOSOMAL_S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 6 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 7" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="5 7" id="KW-0820">tRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ42401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="124" mass="13709" checksum="0121996A1A552C59" modified="2010-01-19" version="1">MATINQLVRKPRAKQVVKSNVPALEACPQKRGVCTRVYTTTPKKPNSALRKVCRVRLTNGFEVTSYIGGEGHNLQEHSVVLIRGGRVKDLPGVRYHTVRGALDCAGVNDRKQGRSKYGVKRPKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1N1</accession>
    <name>D0Z1N1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8">30S ribosomal protein S3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rpsC</name>
        <name evidence="12" type="ORF">VDA_003445</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8 10">Belongs to the universal ribosomal protein uS3 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302798.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003445"/>
    <dbReference type="EnsemblBacteria" id="EEZ42412">
        <property type="protein sequence ID" value="EEZ42412"/>
        <property type="gene ID" value="VDA_003445"/>
    </dbReference>
    <dbReference type="GeneID" id="57340098"/>
    <dbReference type="eggNOG" id="COG0092">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1132353at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1140.32">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01309_B">
        <property type="entry name" value="Ribosomal_S3_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004044">
        <property type="entry name" value="KH_dom_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005704">
        <property type="entry name" value="Ribosomal_S3_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001351">
        <property type="entry name" value="Ribosomal_S3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036419">
        <property type="entry name" value="Ribosomal_S3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018280">
        <property type="entry name" value="Ribosomal_S3_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07650">
        <property type="entry name" value="KH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00189">
        <property type="entry name" value="Ribosomal_S3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="SSF54814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54821">
        <property type="entry name" value="SSF54821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01009">
        <property type="entry name" value="rpsC_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50823">
        <property type="entry name" value="KH_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00548">
        <property type="entry name" value="RIBOSOMAL_S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 10" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 8 10" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 8 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 8" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="KH type-2" evidence="11">
        <location>
            <begin position="39"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ42412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="232" mass="25623" checksum="4E82B52A1B719480" modified="2010-01-19" version="1">MGQKVHPNGIRLGIVKPWNTTWFANSQDFADNLDGDFKVRQFLTKELAKASLSRIVIERPAKSIRVTIHTARPGVVIGKKGEDVEKLRAAVAKIAGVPAQINIAEVRKPELDGQLVADSIASQLERRVMFRRAMKRAVQNAMRLGAKGIKVEVSGRLGGAEIARTEWYREGRVPLHTLRADIDYATSSAHTQYGVIGIKVWIFKGEVLGGMPAANAVEPKADKPKKQRKSRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1P0</accession>
    <name>D0Z1P0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">50S ribosomal protein L6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rplF</name>
        <name evidence="7" type="ORF">VDA_003454</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 5">This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the universal ribosomal protein uL6 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302817.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003454"/>
    <dbReference type="EnsemblBacteria" id="EEZ42421">
        <property type="protein sequence ID" value="EEZ42421"/>
        <property type="gene ID" value="VDA_003454"/>
    </dbReference>
    <dbReference type="GeneID" id="57340089"/>
    <dbReference type="eggNOG" id="COG0097">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1398618at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.930.12">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01365_B">
        <property type="entry name" value="Ribosomal_L6_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000702">
        <property type="entry name" value="Ribosomal_L6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020040">
        <property type="entry name" value="Ribosomal_L6_a/b-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036789">
        <property type="entry name" value="Ribosomal_L6_a/b-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019906">
        <property type="entry name" value="Ribosomal_L6_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002358">
        <property type="entry name" value="Ribosomal_L6_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11655">
        <property type="entry name" value="PTHR11655"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11655:SF14">
        <property type="entry name" value="PTHR11655:SF14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00347">
        <property type="entry name" value="Ribosomal_L6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002162">
        <property type="entry name" value="Ribosomal_L6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00059">
        <property type="entry name" value="RIBOSOMALL6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56053">
        <property type="entry name" value="SSF56053"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03654">
        <property type="entry name" value="L6_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00525">
        <property type="entry name" value="RIBOSOMAL_L6_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 5" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L6" evidence="6">
        <location>
            <begin position="11"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L6" evidence="6">
        <location>
            <begin position="91"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ42421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="177" mass="18908" checksum="BC4D5E66B063F61D" modified="2010-01-19" version="1">MSRVAKAPVVIPAGVEVKLNGQEITVKGGKGELVRVINEAVVLSQEENTITFGPREGFEKAWAQAGTARALVNNMVVGVTEGFTKKLTLKGVGYRAAIKGNAVALTLGFSHPVEHELPAGIKAECPTQTEIVLTGTDKQVVGQVAADIRAYRSPEPYKGKGVRYADEVVRIKEAKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1V4</accession>
    <name>D0Z1V4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cell envelope biogenesis YhbN</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_003518</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003518"/>
    <dbReference type="EnsemblBacteria" id="EEZ42485">
        <property type="protein sequence ID" value="EEZ42485"/>
        <property type="gene ID" value="VDA_003518"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1934">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001530">
        <property type="term" value="F:lipopolysaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015920">
        <property type="term" value="P:lipopolysaccharide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014340">
        <property type="entry name" value="LptA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005653">
        <property type="entry name" value="OstA-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03968">
        <property type="entry name" value="LptD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03002">
        <property type="entry name" value="outer_YhbN_LptA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0574">Periplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="OstA-like_N" evidence="3">
        <location>
            <begin position="2"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ42485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="115" mass="12916" checksum="BE32F08DAA0A4CA7" modified="2010-01-19" version="1">MRQGSIDIRANKVVVTRPQGKEGQETIDAYGTPATFHQVMDDGKPIDGSARKMRYETATEFLKMSDHAVLTQDGSEIKGNVITYKIDEQRLMAKSGSKERVTTILQPNQFNNKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1Z4</accession>
    <name>D0Z1Z4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Hypothetical amidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_001980</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the YkuD family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299079.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001980"/>
    <dbReference type="EnsemblBacteria" id="EEZ40948">
        <property type="protein sequence ID" value="EEZ40948"/>
        <property type="gene ID" value="VDA_001980"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2989">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="975147at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071972">
        <property type="term" value="F:peptidoglycan L,D-transpeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd16913">
        <property type="entry name" value="YkuD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.101.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005490">
        <property type="entry name" value="LD_TPept_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045380">
        <property type="entry name" value="LD_TPept_scaffold_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002477">
        <property type="entry name" value="Peptidoglycan-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036365">
        <property type="entry name" value="PGBD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036366">
        <property type="entry name" value="PGBDSf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038063">
        <property type="entry name" value="Transpep_catalytic_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01471">
        <property type="entry name" value="PG_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20142">
        <property type="entry name" value="Scaffold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03734">
        <property type="entry name" value="YkuD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141523">
        <property type="entry name" value="SSF141523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47090">
        <property type="entry name" value="SSF47090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018773" evidence="4">
        <location>
            <begin position="29"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="domain" description="Scaffold" evidence="7">
        <location>
            <begin position="97"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="PG_binding_1" evidence="5">
        <location>
            <begin position="288"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="YkuD" evidence="6">
        <location>
            <begin position="344"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ40948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="588" mass="66454" checksum="56BF8E2F26DA4500" modified="2010-01-19" version="1">MLNHKRVVTQRAGKLLALSLVFPGSAFATEAFTPVTTNESSTAVTAPEVSAAPQVSEERPAPLTQGNVNWSYLDNANIHSTKTLCVTAVSNVCFTQSIEQAYVDNKFYPLWEEASLRKEFEQQLQAVVDSGLLPGMDQRLQELRNLEQHKDMRAYDLLATDTYFVYQAFEQYIKTHRNQLFTTKPINMSKEMSSYVSNEKAFPMTLARLEQQRPANVNFEATMQAIAKFQALEPNPLKASYLPAVYRKGDRIPHGKAVARVLYDLGDLDQANYDKLMAAKSISNTGVMNDAIKHFQKRYGLSADGIIGKSTAQQLAIPYGELARRLALNMQRANVIAPFAKDKAHILVNIPDYMLKVYENGKVVFDSKVIVGRESRPTNLFSSSINTMVVNPYWNVPITIKQKDVIPKAKRNPGYLAAHNIKVINSWRDRTEIPVSSINWSAVNPKSFPHEFQQGPGPHNSLGMVKFLMPNDYAIFLHDTPARGLFSKTKRDLSSGCVRVARAHDLADFVLDYQNRPSMRTFDSMRKDKGQDTVSLSRRIGVDFVYLTGWVNQDGQVQMREDIYNYDTPSGKKIQSKFITMKDFNHRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z231</accession>
    <name>D0Z231_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001880</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298866.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40848">
        <property type="protein sequence ID" value="EEZ40848"/>
        <property type="gene ID" value="VDA_001880"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502Z9KS">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1039856at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="274" mass="31419" checksum="53B84D4520A16EA6" modified="2010-01-19" version="1">MSLLLVKPGHSRGRSLPLHLAISHNAEIYTIQDLTDCIAYTPTHKLDDGEWFFIDNFNTTNFKDEFIDVQTVVPADYVQLSPNHFSSAKYLCVKEGDFKYYQKLVTSNYVRKKFFNVNDASFIPNGNIITLNDVPDAVYQISTNKLFFKDLSRISVIFTGIDSLYREATDHEVISFLQDDLIHVDNPANFKVGIPNRKKIALAHEKLASFGVNDRAVITNYIQSYYPEITYANNKFIIDDEIKLKNFIYGVEQRFYTTLVGNERRVASSVLTLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z245</accession>
    <name>D0Z245_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Small-conductance mechanosensitive channel</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_001781</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homoheptamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell inner membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the MscS (TC 1.A.23) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298688.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001781"/>
    <dbReference type="EnsemblBacteria" id="EEZ40749">
        <property type="protein sequence ID" value="EEZ40749"/>
        <property type="gene ID" value="VDA_001781"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0668">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1903165at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008381">
        <property type="term" value="F:mechanosensitive ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045275">
        <property type="entry name" value="MscS_archaea/bacteria_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011066">
        <property type="entry name" value="MscS_channel_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011014">
        <property type="entry name" value="MscS_channel_TM-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30221">
        <property type="entry name" value="PTHR30221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82689">
        <property type="entry name" value="SSF82689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82861">
        <property type="entry name" value="SSF82861"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0407">Ion channel</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018829" description="Small-conductance mechanosensitive channel" evidence="8">
        <location>
            <begin position="18"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="279"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="322"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="350"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU369025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ40749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="547" mass="62125" checksum="F74005B40C6D7992" modified="2010-01-19" version="1">MRALVLLMLFVSTLTFAQNSDPELDKLNQLNTEITELQKESVTMTGTSQDVVRLQLLNKNEQMRDVLSGLVANHTEEDKDKIVGQVRQQIQFIGTATTYLNKKIKDDEKKLDKASNEEKLLAQKNLDEARRFSVRLLGEQWQNYQWMKTLGLPQPKSEQRLMSEVEHQLEFMSAALNFNSQQEELLGKQLKSAAESEKASVQIMHILAQRKVASDTQSLTYLAGVADKMGIDTSEYKQQLFETTGNVTNDLLNTKVIWSIVSSWTHELGSWVFANAPQMLFKILIFVLIIFLARVLKNLTRKMVKRAVTSPNLKMSQLMQEFFISMSGKGVFCIGLLIALSQIGLDLTPILTGFGVAGVIIGFALQDTLSNFASGMMLLIYRPFDVGDFVEAGSVSGKVSHMSLVNTTIKTFDNQIIIVPNSKIWGDIIKNVTHERVRRVDMIFGISYSDDIELTEKVLHEIVESHESVLRSPEPTIKLHTLNSSSVDFIVRPWVKTEDYWDVYWDITREVKMRFDREGISIPFPQQDVHLHMVEKKDETNVVSKQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z246</accession>
    <name>D0Z246_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hypothetical membrane spanning protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001782</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001782"/>
    <dbReference type="EnsemblBacteria" id="EEZ40750">
        <property type="protein sequence ID" value="EEZ40750"/>
        <property type="gene ID" value="VDA_001782"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2199">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="391"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="2">
        <location>
            <begin position="441"/>
            <end position="565"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="565" mass="65450" checksum="9DE14707DD6001AB" modified="2010-01-19" version="1">MTSKFIKVIICIMIISVTTYVIKINMDVKKSPISLIDVVNNKDEQSVLDFKLKCVTDECEVINSFLSLPVSSYPYEYQEIAESIRPILHTPQGAKIGVTILTQVKDALSDNKPAQLYLLRKISTLRFLSQDLYGMIQPSIEYLALAKEEGDPYLIAVGTVNLASIISYFEGYSTSNRLLQNLLSSHMGHSDKWQRLKIRSLLILAENKIANGEYYKASLTLNDVIKNKPKMPYNEWDDYLIYILALKSEIAINLGLKDESYKLIKQAKGLLENDSHNFLVDKDIAVKSVELQWLLKNDNHIEQHIDLPELLNRYTAATNTRYVKMLYKGLLKYYYSKENYDDYYKLRQTYEAEMEKRAGISYKLLFSNATSNINNKSLKNNNDLYIKRFEWLTYVLLGLVLLLTFVLFKVVHLQRENVLDGLTLIGNRKKYNNTLKEIGNRPYYLALFDIDDFKQINDHYGHDFGDLVLQEISQKIDFILPKVAQIFRIGGEEFAIVIRHHDPLFVKREMDRVRQFIQNIKWPDESLQVTVSMGVELSVNGSDIYKLVDEKLYLAKKLGKNRVEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z263</accession>
    <name>D0Z263_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Anaerobic sulfite reductase subunit A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001910</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298918.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001910"/>
    <dbReference type="EnsemblBacteria" id="EEZ40878">
        <property type="protein sequence ID" value="EEZ40878"/>
        <property type="gene ID" value="VDA_001910"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0479">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1092632at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014259">
        <property type="entry name" value="Sulphite_reductase_A"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17179">
        <property type="entry name" value="Fer4_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02910">
        <property type="entry name" value="sulfite_red_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="219"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="302"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="348" mass="40254" checksum="496E76A40CC9A83A" modified="2010-01-19" version="1">MSKYLNNTELERLISELKCSYQIMAPTYEHFGGRFAHTDNLIYKNIHSASEIVWYEKSHFSAKEIIFPITQTLFHFHGDMIIEPEHTAKPTIVFLRACDIHALERLDYMFLENGGNRDIYYQTLRDKLKLILIECEHSFDSCFCVSMGTNETDNYAAAIRVSTDGAVIQVKDETLIPFFAELGSDREYEPKFVQENQIKVRLPDQVCSDPQKIRQILQNDPSWAEYDRRCIGCGRCTTSCPTCSCYSVFDFAYDENPTYGERRRQHASCMVGDFTAIAGGHSFRDKTGERLRFRALHKVNDYKARQGTHHMCVGCGRCIDRCPQYISFTRIINRMTDIVENAIKSEQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-08-12" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2H9</accession>
    <name>D0Z2H9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Divalent metal cation transporter MntH</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">mntH</name>
        <name evidence="5" type="ORF">VDA_000630</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">H(+)-stimulated, divalent metal cation uptake system.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the NRAMP family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000630"/>
    <dbReference type="EnsemblBacteria" id="EEZ39610">
        <property type="protein sequence ID" value="EEZ39610"/>
        <property type="gene ID" value="VDA_000630"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1914">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046873">
        <property type="term" value="F:metal ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00221">
        <property type="entry name" value="NRAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001046">
        <property type="entry name" value="NRAMP_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11706">
        <property type="entry name" value="PTHR11706"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01566">
        <property type="entry name" value="Nramp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00447">
        <property type="entry name" value="NATRESASSCMP"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01197">
        <property type="entry name" value="nramp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0406">Ion transport</keyword>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0769">Symport</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="59"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="98"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="126"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="161"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="203"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="245"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="292"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="331"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="355"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="392"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="415" mass="44638" checksum="9E6F352B53E388A8" modified="2010-01-19" version="1">MSMSITTADKAEVYNTTISKFKRKLLLLGPAFIAAIGYIDPGNFATNIESGSSYGYQLLWVVLWANLMAMLIQYLSAKLGIVTGKNLAEHLRDHLPKWAIGPYWVQAEIIAIATDLAEFIGAAVGFQLVFGISLMEGAIITAVASILILMLNKRGQKPLEAVIGSLLMLVAVIYVVELFYAGPSSSELSKGLIIPSFNSAHEIYLAAGILGATVMPHVIYLHSALFKNSYGEKTETRLRSTKVDVLIAMVIAGFVNIAIVAMAAAVFHYSGNQHVAEIETAYMTLTPLVGKAASLLFGISLIASGLSSTVVGTMAGQVVMQGFVHFKIPMWVRRSVTMIPSFIVIGLGLDTTQILVMSQVVLSFGIALAIIPLLMFTNSERLMGEFKNTKTVNILGVVIVTLVLALNGYLMVTLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2M6</accession>
    <name>D0Z2M6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Isopentenyl-diphosphate delta-isomerase</fullName>
            <ecNumber evidence="1">5.3.3.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000677</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="5.3.3.2" evidence="1"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000677"/>
    <dbReference type="EnsemblBacteria" id="EEZ39657">
        <property type="protein sequence ID" value="EEZ39657"/>
        <property type="gene ID" value="VDA_000677"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3044">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004452">
        <property type="term" value="F:isopentenyl-diphosphate delta-isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019195">
        <property type="entry name" value="ABC_ATPase_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38149">
        <property type="entry name" value="PTHR38149"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09818">
        <property type="entry name" value="ABC_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="471" mass="52650" checksum="F9585ADDA98F393A" modified="2010-01-19" version="1">MARFFAELAQHENAILIDRPGQVILDRTAVVFDDEGIELRFRVNLPSDGRTIIAKRTLNLLTFHMPKIIRRATIARELPMEELQRHCEAAENQVALRNQLAEHNLVSFVADGSILPRLAGNSQLPMPDAIPFKSPDALAIELDTPHNGKIRGMGIPKGITMIVGGGFHGKSTLLGAVESSVYDHIPGDGREYIVTDETATKIRAEDGRCVHNVDLSPYISNLPMGKDTTKFSTQDASGSTSQASWLQESLEAGAQTLLIDEDTSASNFMIRDERMQALIAKDEEPITPLVDRIALLRDQLDVSVMLIMGGSGDYLDVADTVIQMHNYEAIDVTEKARQVVASHPTRRSFEGSETIARPRTRQLNRSALKLMLEEGKFRIQAKNKHSLRFGREFVDLQALEQIAHQSQLHAIGCLWFMMAQNKGWEKAPVRAFAQMLNENWATMMPRYGDLAKPRVMEIMAVLNRMRAAEFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2Q3</accession>
    <name>D0Z2Q3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glutathione S-transferase</fullName>
            <ecNumber evidence="3">2.5.1.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000704</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.5.1.18" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305108.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000704"/>
    <dbReference type="EnsemblBacteria" id="EEZ39684">
        <property type="protein sequence ID" value="EEZ39684"/>
        <property type="gene ID" value="VDA_000704"/>
    </dbReference>
    <dbReference type="GeneID" id="57343041"/>
    <dbReference type="eggNOG" id="COG0625">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1560019at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="SSF47616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="41"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="2">
        <location>
            <begin position="135"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="285" mass="32105" checksum="FCACD474323AA3A5" modified="2010-01-19" version="1">MTNQYVPPQVWAPDTNNGGQWASINRPVSGATHQRELPVGEHPIQLYSMGTPNGQKVTIMLEELLAKGFANAEYDAHLIKIGDGDQFSSGFVEINPNSKIPALVDQSVSPAINIFESGSILLYLAEKFGCFLPQEIAAKTTVMNWLFWLQGSAPYLGGGFGHFYAYAPEKFEYPINRFTMEAKRQLDVLDKQLAKHRYIAGDEYSIADMAIWPWYGNLVLGRLYDAAKFLDVDGYVHLQRWAKEIDARPAVARGRIVNRAWGEVWEQVPERHCADDIDNIMKLKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z312</accession>
    <name>D0Z312_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Long-chain-fatty-acid--CoA ligase</fullName>
            <ecNumber evidence="2">6.2.1.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000813</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="6.2.1.3" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000813"/>
    <dbReference type="EnsemblBacteria" id="EEZ39793">
        <property type="protein sequence ID" value="EEZ39793"/>
        <property type="gene ID" value="VDA_000813"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1022">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004467">
        <property type="term" value="F:long-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="25"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="562" mass="63426" checksum="218D0424DD2012E9" modified="2010-01-19" version="1">MSVPLNYPSKDFMMDQSLPYNMLIQWAEKKPNEVFLRQIINREFTDYTYADVLDKALRLVSCLRDMGIQPGDRVALIAKNCAEWFITDLAMMLGSYISVPIFPTAGADTIEHCITHSESKIILIGKLDDEKAVNSVCAKHAYIPTIGFNYSTAPKCQYQFDELIAKYEPSQERPQHSHEDIMSIVYTSGTSGLPKGAMLSYGAFAWSSQRLIEHIGIKENERLFSYLPLAHITERVYIFGTSVQAGIQVAFPESLDTFIDDVKMHRPTLFISVPRLWTLFQQRIHEKLPPAKLNLLLKIPFISGLIKRKLADGLGLDKARVLGCGSAPVSPALLEWYRHIGLNITEAWGMTESFAYSTLNYPFRADKIGSVGNAGPGIEIKLTAEEEILVRGKGLFSGYYKNEEATKETIDEDGWLHTGDLGSIDEDGYITIEGRIKDTFKTSKGKFVAPVPIEKRLFELSNLELMCIIGSGMPGPILLAVPHSFPNFDRARYEKRVHKVIAKLNSELESHAQIRGVLMIKEPWSIENGILTPTLKIKRHILEKQYHEIGSNWPKNTLIQWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z369</accession>
    <name>D0Z369_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0502 protein VDA_000870</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000870</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0502 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305584.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39850">
        <property type="protein sequence ID" value="EEZ39850"/>
        <property type="gene ID" value="VDA_000870"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3132">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1721848at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01584">
        <property type="entry name" value="UPF0502"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007432">
        <property type="entry name" value="DUF480"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38768">
        <property type="entry name" value="PTHR38768"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04337">
        <property type="entry name" value="DUF480"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="185"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="218" mass="24571" checksum="7E8BA44D50BF63D8" modified="2010-01-19" version="1">MDINFSQNEARIIGCLLEKEVTTPDQYPLTLNALTTACNQKTNREPVLALTEAEVMDSVEELKEKRLINELVGFGSRVPKYKHRFCNTEFGSLQFSKQEFAVICVLLLRGPQTAGELRTRTNRLCDFKDVKEAEEVLTKLAEHEKGPYVVKLPKEPGKRDCRYMHLFSGEVDISTLAASTSVSNSSASSSRIEQLELEVQALKQELAELKETVQMLTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z390</accession>
    <name>D0Z390_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000891</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305645.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000891"/>
    <dbReference type="EnsemblBacteria" id="EEZ39871">
        <property type="protein sequence ID" value="EEZ39871"/>
        <property type="gene ID" value="VDA_000891"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5033NB6">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2006458at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018869" evidence="1">
        <location>
            <begin position="24"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="185" mass="21323" checksum="567C6DA97A5593F9" modified="2010-01-19" version="1">MFSVLFRSFILMLCLGLTSVAHADARTKFEQDFYHLSVNANQLVIEDTNSPFDIATLYRQIHIDETVASYPFARQDKLIWNFANQAEEESHGDHQSRESHDIRLGLANSSRFLSMAHHDPDEVQPLYYLAHEISVPSILSIAKSYSEDLCPTLDWILKIKPSSNRISGWKESNLTYRIYSHQYLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3A4</accession>
    <name>D0Z3A4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Pyruvate formate-lyase</fullName>
            <ecNumber evidence="6">2.3.1.54</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_000905</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.3.1.54" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305684.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000905"/>
    <dbReference type="EnsemblBacteria" id="EEZ39885">
        <property type="protein sequence ID" value="EEZ39885"/>
        <property type="gene ID" value="VDA_000905"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1882">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="116406at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008861">
        <property type="term" value="F:formate C-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019777">
        <property type="entry name" value="Form_AcTrfase_GR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001150">
        <property type="entry name" value="Gly_radical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010098">
        <property type="entry name" value="PFL2/GDeHydtase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004184">
        <property type="entry name" value="PFL_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01228">
        <property type="entry name" value="Gly_radical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02901">
        <property type="entry name" value="PFL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01774">
        <property type="entry name" value="PFL2-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00850">
        <property type="entry name" value="GLY_RADICAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51149">
        <property type="entry name" value="GLY_RADICAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51554">
        <property type="entry name" value="PFL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="1 2" id="KW-0556">Organic radical</keyword>
    <keyword evidence="6" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PFL" evidence="5">
        <location>
            <begin position="8"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="domain" description="Glycine radical" evidence="4">
        <location>
            <begin position="686"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="673"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="modified residue" description="Glycine radical" evidence="2">
        <location>
            <position position="783"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ39885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="807" mass="89586" checksum="18A4C2A0807B73DE" modified="2010-01-19" version="1">MDLNYLPERIKAHKSALVNIVTPPVCTERAEAYTRAYQANEDKPVIVQRALALQEHLRTRTIWIKHDELIVGNQASKVRAAPIFPEYTVRWIEAEIDELADRPGAGFAVTEEDKQSIHSITPYWRGKTVQDRCYGLFTDEQKEILASTIIKAEGNMTSGDAHLAVDNEKILKLGMNGLLEDVRQHRANNDISTFEGLQKEQFYKSVEIVLLAIQAHMMSYAELAAKMALEEKRPLRKAELESIAANCRHIASDAPESFWQALQLSYFVQLMLQIESNGHSVSFGRMDQFLNEFYVRDIENGTIEKDFALELLQSCWLKLLEVNKIRSGAHSKASAGSPLYQNVCIGGQKLNEQGEPEDAVNPLSWAILESCGQLRSTQPNLSVRYHEGLNQEFLMGCVEVIKCGFGMPAFNNDEIVIPEFIKLGVEKEDAYNYASIGCIETAVPGKWGYRCTGMSFINFARILLAALNEGVDATTGKAFLPHDKSLAKGNFENFEQVTASWAEQIRYYTRKSIEIDTVVDSVLEQQAQDIFCSTLVDDCLARGKTVKEGGAKYDWVSGLQVGIANLGNSLAAIKHLVFDDAQITQPELAKALAEDFEGMENEQLRQRLINYAPKYGNDDDSVDQLLADAYQVYIDELEQFVNTRHGRGPIGGGYYAGTSSISANVPFGASTMATPDGRKAKTPLAEGASPSSGSDRLGPTAVYNSVGKIQANKILGGVLLNQKLSPAAVESEGDKLKLSMLIRTFFNHHKGWHVQYNIVSRETLLAAKKNPEQYRDLVVRVAGYSAFFTALSPDAQDDIIARTEHSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3E9</accession>
    <name>D0Z3E9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Multidrug resistance efflux pump</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000950</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305810.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000950"/>
    <dbReference type="EnsemblBacteria" id="EEZ39930">
        <property type="protein sequence ID" value="EEZ39930"/>
        <property type="gene ID" value="VDA_000950"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1566">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="757027at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039562">
        <property type="entry name" value="MFP_biotin_lipoyl_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13533">
        <property type="entry name" value="Biotin_lipoyl_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="domain" description="Biotin_lipoyl_2" evidence="2">
        <location>
            <begin position="70"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="407" mass="45398" checksum="DB527540678818A3" modified="2010-01-19" version="1">MLEGLAVWALFIYLLRLVGMPWNKFTKSFAYLGGGGWLVFVWFGLITFAPMDLSGGSLVQSPHIQLRPASSQIKGHVKAIHVEPNQTVEKGQLIYELDDEPYRIALTKAETKLDSAHVDLKMAIEDVANAKTQYRSAVKDIDITKNQLVAAKEDLRFKQATLNRYVKQNQVVKHTVTESMLDEQRTAVKVGKAQVTTLDSQVEKAVIASEQAKVRLEQAQLAVTSREVAVKSEQENVAQAQWNLEHTQVYAPADGYLTNFIMREGQYVGVAPRIQMYTDEKYVLMRVNHQAIRNVKAGQMAEFASAVYPGKVFAAEVEGIIEATGEAQGSLLARDDNVRQTTGANIANKHHFVRLKLIETEGYDIPVGSVGLAWVSAEKPIGFLGFLDVIRGIIIRMKSQIFYVWSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3R3</accession>
    <name>D0Z3R3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Chondroitin sulfate ABC lyase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Chondroitin ABC eliminase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Chondroitin ABC lyase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Chondroitinase ABC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_001064</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Broad-specificity glycosaminoglycan lyase.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the polysaccharide lyase 8 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306125.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001064"/>
    <dbReference type="EnsemblBacteria" id="EEZ40044">
        <property type="protein sequence ID" value="EEZ40044"/>
        <property type="gene ID" value="VDA_001064"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502Z8J1">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="941406at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034000">
        <property type="term" value="F:chondroitin-sulfate-ABC endolyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006027">
        <property type="term" value="P:glycosaminoglycan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039174">
        <property type="entry name" value="Chondroitin_ABC_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008929">
        <property type="entry name" value="Chondroitin_lyas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024200">
        <property type="entry name" value="Chondroitinase_ABC_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011071">
        <property type="entry name" value="Lyase_8-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003159">
        <property type="entry name" value="Lyase_8_central_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015177">
        <property type="entry name" value="Lyase_catalyt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015176">
        <property type="entry name" value="Lyase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37322">
        <property type="entry name" value="PTHR37322"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02278">
        <property type="entry name" value="Lyase_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09093">
        <property type="entry name" value="Lyase_catalyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09092">
        <property type="entry name" value="Lyase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF034515">
        <property type="entry name" value="Chondroitinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48230">
        <property type="entry name" value="SSF48230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49863">
        <property type="entry name" value="SSF49863"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="SSF74650"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0106">Calcium</keyword>
    <keyword evidence="2" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003020059" description="Chondroitin sulfate ABC lyase" evidence="5">
        <location>
            <begin position="20"/>
            <end position="1026"/>
        </location>
    </feature>
    <feature type="domain" description="Lyase_N" evidence="7">
        <location>
            <begin position="47"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="Lyase_catalyt" evidence="8">
        <location>
            <begin position="246"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="domain" description="Lyase_8" evidence="6">
        <location>
            <begin position="623"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="376"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="486"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="493"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR034515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR034515-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR034515-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF09092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF09093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ40044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="1026" mass="114527" checksum="28CA8C1CD91AD177" modified="2010-01-19" version="1">MKHPLLPSILTISLSLALAGCNNESIQNAPNVDGKGAQLEPGGYMYFFEQDVPQAITTTATQSLAVTNRHYKDGAQSLRWQFDPTTMLTFHQAIGYSPEKEDAITPQTFTAWIYNEKPIDDSLLFEFGTDDSTQVKFHYRLNFKGWRGIAVPYRNMQGQANANMDRLRIIAPQASGTIYFDQMMMSVPVDNRWPTADYQQPFVNPTVVDMASKNWTALMMYDEMLKEHHATFDFTVPFDDTSGDTANLYQQFDQYLAVNPHATITQQQIDKNLASYQKFALTQNTDGSWQGKPLDHPKRQNYLKTGILDDATLAMVTDTANIRDLGKILLESAKLLRSESLSNANRAALEKAFINAVSYSFDQGWQGGSGLQVITHVGYQTREYFDALFIARQLLAQHHLLQSAQQSMMWFNATGRIYETDQDITASNVDILNTQLQWMIKSFLLLPNSSERHDMLQQLQTWLSKTLLASDGLGGGFKPDGSIFHHSQHYPAYGKDAFSGLAGAVFGLSNSPYQITPQAHSRIKDALLKMRIYTKETNTPIVLSGRHPDGKQKITATPFKWLALAGSPDQTHLIDPELAAAFANLTNKTEFEGIKAENEPVGSWAMNYASMAVVRGSSHSDTQKSWLATARGFSRYLVGNETYAANNLYGRYLQYGQLEITPADYSLRAFSHDGWDWNRYPGTTTIHLPNNKLKAVLNQLSGAGIEEMLLSTEAYSGANRLDDHMAMFAMKLQGHKKYQQQGFTANKSYFIFDNNVIALGSNINSDDPLYPVETTLFQHSVSSLEPIEVNGTPISNLDYADSLSGEITLQDPAHNYYFISATNEQPLNISYQTQTSNDEDDGKVTTGNFASAVIEHGIQAKNRSYEYAITIDGTEAVKPKYHVLQQDINLHAVEKDGIEAYAFFAPTQVTSNTHVVSAETPMQIIAKPNQQGDELALSIVNPDFAFYKGQDPDQIDENGDQVEVSIYSRPWRYDLSQPVTSIFTVKGHWQLAAPSDKVQTSIDGENTKVTTTTTDAEVLQFGLIAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3V5</accession>
    <name>D0Z3V5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001108</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306243.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40086">
        <property type="protein sequence ID" value="EEZ40086"/>
        <property type="gene ID" value="VDA_001108"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG50319VU">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1337280at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="275" mass="31017" checksum="E3701B03BABE1538" modified="2010-01-19" version="1">MKKTQEQFVEKATIVHNGKYIYNHFIYVNAKTKSMITCPVHGDFEQRPDAHLAGRGCPKCAGKEKKTKEEFVINARKIHGTKYDYSKFEYLGSLNKSTIICPQHGEFEQRPNAHLSGKGCPKCSKSYPKSQSMFIEKANETHQNKYSYGHFIYSGALEKGIITCPEHGDFEQRADAHLRGVGCPQCAKNGRKKTTAQFIKEAQQVHGKLYDYSQFIYTNVRTKGVIICAQHGKFEQLPSNHLSGNGCPKCAAEKKCSTRRSHCKSKHYSASISLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3V8</accession>
    <name>D0Z3V8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Acetate kinase</fullName>
            <ecNumber evidence="6">2.7.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Acetokinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ackA</name>
        <name evidence="8" type="ORF">VDA_001111</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>acetate + ATP = acetyl phosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:11352"/>
            <dbReference type="ChEBI" id="CHEBI:22191"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="6">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="6">Mg(2+). Can also accept Mn(2+).</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the acetokinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.1" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306251.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001111"/>
    <dbReference type="EnsemblBacteria" id="EEZ40089">
        <property type="protein sequence ID" value="EEZ40089"/>
        <property type="gene ID" value="VDA_001111"/>
    </dbReference>
    <dbReference type="GeneID" id="57343428"/>
    <dbReference type="eggNOG" id="COG0282">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="537106at2"/>
    <dbReference type="UniPathway" id="UPA00340">
        <property type="reaction ID" value="UER00458"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008776">
        <property type="term" value="F:acetate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006085">
        <property type="term" value="P:acetyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006082">
        <property type="term" value="P:organic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00020">
        <property type="entry name" value="Acetate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004372">
        <property type="entry name" value="Ac/propionate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000890">
        <property type="entry name" value="Aliphatic_acid_kin_short-chain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023865">
        <property type="entry name" value="Aliphatic_acid_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21060">
        <property type="entry name" value="PTHR21060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00871">
        <property type="entry name" value="Acetate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000722">
        <property type="entry name" value="Acetate_prop_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00471">
        <property type="entry name" value="ACETATEKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00016">
        <property type="entry name" value="ackA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01075">
        <property type="entry name" value="ACETATE_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01076">
        <property type="entry name" value="ACETATE_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 7" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton donor/acceptor" evidence="6">
        <location>
            <position position="147"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="17"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="207"/>
            <end position="211"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="281"/>
            <end position="283"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="329"/>
            <end position="333"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="383"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="6">
        <location>
            <position position="179"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="6">
        <location>
            <position position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ40089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="397" mass="43224" checksum="AEF0E8FF0C6A9A2A" modified="2010-01-19" version="1">MSNSLVLVINSGSSSLKFALIDTVTGDAMLNGLGECFFLPEAVVSWKVNGEKHEYKLSGLENHHQQAIDRIVALVDELGLKEDIVAIGHRVVHGGTKFSHTVKVDEQVMADIEALSDLAPLHNPAHVIGMRAAAKAFPTLSQYAVFDTAFHQTMPEKAFTYAISKEVSKEYDIRRYGAHGTSHYYVTREAAKVVNKPVEASSFISVHLGNGASVCVVKNGESIDTSMGFTPLAGLMMGTRCGDIDPSVLEYLLKKGWTPEQLHDLLVKKSGFLGISGITSDCRGIIEAMEQGNHDAKLAFEVFTYRAAKYIASYMVALDELDGIIFTGGIGENSMPVRSEILRLLKIFGYREDEQANADARFGNSGVITQANTPLAMVIPTNEEWVIANESMALLHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3W0</accession>
    <name>D0Z3W0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mutator family transposase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_001113</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">Required for the transposition of the insertion element.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the transposase mutator family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306256.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40091">
        <property type="protein sequence ID" value="EEZ40091"/>
        <property type="gene ID" value="VDA_001113"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3328">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="792870at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001207">
        <property type="entry name" value="Transposase_mutator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33217">
        <property type="entry name" value="PTHR33217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00872">
        <property type="entry name" value="Transposase_mut"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01007">
        <property type="entry name" value="TRANSPOSASE_MUTATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0814">Transposable element</keyword>
    <keyword evidence="4 6" id="KW-0815">Transposition</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="402" mass="46620" checksum="63F3F2CDB1E84D66" modified="2010-01-19" version="1">MDKKALEAFAREAAKSIKTESDLDDFRKMLTKVTVETALNAELDEHLGYQKHQARTNSNSRNGYSGKSIITDDGEVDIEIPRDREASFEPQLIRKHQTRFQSMDDKILSLYAKGMTTREIVATFKEMYDADVSPTLISKVTDSVLEQVIEWQSRPLDEVYPIVYLDCIVIKVRQDKQVINKAVYLALGVNMEGQKELLGMWLSETEGAKFWLNVLTELQNRGVNDILIACVDGLKGFPDAINTVFPETQIQLCIVHMVRNSVKYVPWKDYRAVTVDLKKIYQSATEDEALLALEQFSARWDSKYPQISRSWTTHWDNLNTLFNYPEDIRRAIYTTNAIESLNSVIRKAIKKRKLFPTDESARKVIYLAIRDASKKWTMPIRNWRQALNRFMIMFEDRLSEYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3W1</accession>
    <name>D0Z3W1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative chloramphenicol acetyltransferase</fullName>
            <ecNumber evidence="1">2.3.1.28</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001114</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.3.1.28" evidence="1"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306260.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001114"/>
    <dbReference type="EnsemblBacteria" id="EEZ40092">
        <property type="protein sequence ID" value="EEZ40092"/>
        <property type="gene ID" value="VDA_001114"/>
    </dbReference>
    <dbReference type="GeneID" id="57343426"/>
    <dbReference type="eggNOG" id="COG0110">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1878940at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008811">
        <property type="term" value="F:chloramphenicol O-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="218" mass="24760" checksum="F80D78CA0C70A208" modified="2010-01-19" version="1">MPSTIFPSWLGGYEIREHITNPNIKVGEYTYYSGYYHEKHFEDQCVRYLLGDKPSASVWESGIFGEIDQLIIGKFCSIATGATFMLAGNQGHRHDWISTFPFDVEQFGDKVKSGFQRAGDTRIGNDVWIGTECVIMPGVTIGDGAVIGARAVVTKDVEPYSIVVGNPGTAIKKRFTEQEIEMLLKMQWWDWTENQLKDNMDLMCSSNISELYQRFLQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3Z0</accession>
    <name>D0Z3Z0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator AraC/XylS family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001143</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306330.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001143"/>
    <dbReference type="EnsemblBacteria" id="EEZ40121">
        <property type="protein sequence ID" value="EEZ40121"/>
        <property type="gene ID" value="VDA_001143"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1268974at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020449">
        <property type="entry name" value="Tscrpt_reg_HTH_AraC-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00032">
        <property type="entry name" value="HTHARAC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="4">
        <location>
            <begin position="156"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="255" mass="28613" checksum="EB59F30B5EACC5B5" modified="2010-01-19" version="1">MQSCLPTCSKIVALPDEMDHHHHDHHQLVIGVSGRSEFEIEGKGNVISKGQGCIVSSDAEHAFSGLGTNEILVVNLPSHFEGLLADHHQLESLFDHSYYFSLDLQAQTLIQALSTELSSAPNDLLLSQSCSNMLLCSLQRHIQDPHKHVNHRLNMDHLDLYIESHLSTKISVSELAGSAFLSDSQFFLLFKQQVGMTPHQYVLHKRLHRAKHLLIHSQLSLMDISQHCGFASQSSFTQSFSRLFSISPARFRKMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z400</accession>
    <name>D0Z400_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transmembrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001153</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306359.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001153"/>
    <dbReference type="EnsemblBacteria" id="EEZ40131">
        <property type="protein sequence ID" value="EEZ40131"/>
        <property type="gene ID" value="VDA_001153"/>
    </dbReference>
    <dbReference type="GeneID" id="57343374"/>
    <dbReference type="eggNOG" id="COG0861">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1917125at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005496">
        <property type="entry name" value="Integral_membrane_TerC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03741">
        <property type="entry name" value="TerC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="154"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="184"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="213"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="254" mass="28089" checksum="5AD4C706ACD64B70" modified="2010-01-19" version="1">MLELFLQPESWMILATLFTLEVVLGVDNIVFISVLCERLPVHQQKMARNLGITLAVAARIVLVFSISWVMSLTEPLLTMAETVFTGRDLIMIGGGAFLLAKSLKELWMWLTHNEEHNASTVRAGITLVLLQIVAVDAVFSMDSVITAVGMTDEIPLMVAAILAAAVVMMLCAEKINTYVTRYPGFKTLALLFLVLLGGLLMAEGFAIHINKGYVYFAMAFGLTMEMCHILLKKKRSKVIKSIQPQPMGWAIKAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-12-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z413</accession>
    <name>D0Z413_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative alpha-1,2-mannosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001166</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306390.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001166"/>
    <dbReference type="EnsemblBacteria" id="EEZ40144">
        <property type="protein sequence ID" value="EEZ40144"/>
        <property type="gene ID" value="VDA_001166"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3537">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="100818at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005887">
        <property type="entry name" value="Alpha_mannosidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041371">
        <property type="entry name" value="GH92_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012939">
        <property type="entry name" value="Glyco_hydro_92"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07971">
        <property type="entry name" value="Glyco_hydro_92"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17678">
        <property type="entry name" value="Glyco_hydro_92N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01180">
        <property type="entry name" value="aman2_put"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019981" evidence="1">
        <location>
            <begin position="22"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_92N" evidence="3">
        <location>
            <begin position="43"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_92" evidence="2">
        <location>
            <begin position="304"/>
            <end position="804"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="809" mass="89871" checksum="AC3471CE992FA9BB" modified="2010-01-19" version="1">MSLKLLPLTAAIALVLSGCNSDNSTFDGKDNIETPIDQSVLQYVDPLIGTADAGHTFPGAVVPSGMVQLSPDTQLTGWHSSSGYHDPSDYTKGTIIDKDLPLYGFSHTHLSGTGIGGLGDISFLPFSHDNQSEKASFAKVNEVAQAGFYQVTLDESDIKVELTASERVGFHRYTFAPDQPQQLKVDLNTTLNTDWGSKSMRNKITIIDDYTIIGERDSHGFGGWSMNQRVYFYAKFDRKIKSIQLTVEGEPVKGNSAESISRIVTDDAGKKRRIQADVTAFIEFEPSNEPVVAKVALSPVSTEGAEKNYQQEANITFDQAKQQAKQKWAESLNDIKVTGGSADQKEIFYTALYHTKIAPMIHQDVDGQYRGMADGTQVQNFTNGEGETNYSVYSMWDTFRSLHPLKTITEPERAVEYAKNLIKKQQEGGLLPKWELHGDYSGTMVGYPAVSIIADAMIKYPESFSDQERKDALAAALASSNYHPEDFQHWHQGLLNKVLTPHIKYIAELGFAPAVERDGEGNLINGTTESVSYGLENAYYDWCIAQMAKLAGSDAIYLEYMKRSKAYKRYFDHNPARYAEHNSTGFMRPIMSDGSWSTPFDPYNAVHETGNYTEGNAWQWTWFVPHDINGLKYVMGGEAAFLSNLDALFNAKPLEGTADMTGLIGQYVHGNEPDHHVAYLYNYTSEPWKTQEYVDYILDTFYTTLPNGIIGNEDVGAMSSWYVMSALGFYQVSPGSTVYTIGRPLFDEADIPVKGGVFKVIAENNSDDNYYVQSVSINGKPLTDGVFFNHSDIKAGGELRFVMTDQKPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-08-12" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z415</accession>
    <name>D0Z415_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">L-seryl-tRNA(Sec) selenium transferase</fullName>
            <ecNumber evidence="5">2.9.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Selenocysteine synthase</fullName>
            <shortName evidence="5">Sec synthase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Selenocysteinyl-tRNA(Sec) synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">selA</name>
        <name evidence="8" type="ORF">VDA_001168</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>H(+) + L-seryl-tRNA(Sec) + selenophosphate = L-selenocysteinyl-tRNA(Sec) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:22728"/>
            <dbReference type="Rhea" id="RHEA-COMP:9742"/>
            <dbReference type="Rhea" id="RHEA-COMP:9743"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16144"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:78533"/>
            <dbReference type="ChEBI" id="CHEBI:78573"/>
            <dbReference type="EC" id="2.9.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 5 6">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5">Aminoacyl-tRNA biosynthesis; selenocysteinyl-tRNA(Sec) biosynthesis; selenocysteinyl-tRNA(Sec) from L-seryl-tRNA(Sec) (bacterial route): step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SelA family.</text>
    </comment>
    <dbReference type="EC" id="2.9.1.1" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001168"/>
    <dbReference type="EnsemblBacteria" id="EEZ40146">
        <property type="protein sequence ID" value="EEZ40146"/>
        <property type="gene ID" value="VDA_001168"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1921">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1124266at2"/>
    <dbReference type="UniPathway" id="UPA00906">
        <property type="reaction ID" value="UER00896"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004125">
        <property type="term" value="F:L-seryl-tRNASec selenium transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001514">
        <property type="term" value="P:selenocysteine incorporation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097056">
        <property type="term" value="P:selenocysteinyl-tRNA(Sec) biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00423">
        <property type="entry name" value="SelA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018319">
        <property type="entry name" value="SelA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004534">
        <property type="entry name" value="SelA_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025862">
        <property type="entry name" value="SelA_trans_N_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12390">
        <property type="entry name" value="Se-cys_synth_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03841">
        <property type="entry name" value="SelA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00474">
        <property type="entry name" value="selA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="5 6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0711">Selenium</keyword>
    <keyword evidence="5 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Se-cys_synth_N" evidence="7">
        <location>
            <begin position="21"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="5 6">
        <location>
            <position position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR618319-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ40146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="475" mass="52476" checksum="D404B77835CB7092" modified="2010-01-19" version="1">MTLYSEPDVKSPPITSKPNFRLPQVEKLLQQAEFQIYIEQLSRPVVTDIIRTLFAKLRLDSQFQAQGVAAFDINQLVRQRCQIIREQRQQRVINATGIAVHTNLGRSPIHQQLWQQVSELNTSYSNLELKLSDGKRGERNGLLSSLVHSWLGAEECVVVNNNAASIYLALHGLAAGKEVIVSRGEQIQIGGGFRIPDILALSGCTLVEVGTTNITTSDDYINAITENTAMVLMVHQSNFSMQGFTESPDISDVAKRLPEHIALVVDQGSGLSSESYAQSETALQTYLKMGADLVCFSGDKILGGPQAGIIAGDKALCLRLSKNPMMRAFRSSRIVLSLLEQLLIDKLNKKESGKGIAERTLQALAEKKHLAEQLAKRWKPFSCITELQMQVGGGSIPTETYPCLGLTLTLPGKAQQHLEALRSFAVPIIGYLNRNQLILNVATLLPHDIDIFIQQLDSYIAQFNVHKTKTHKETL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z420</accession>
    <name>D0Z420_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Hydrogenase-4 component C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_000276</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303920.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000276"/>
    <dbReference type="EnsemblBacteria" id="EEZ39258">
        <property type="protein sequence ID" value="EEZ39258"/>
        <property type="gene ID" value="VDA_000276"/>
    </dbReference>
    <dbReference type="GeneID" id="57343347"/>
    <dbReference type="eggNOG" id="COG0650">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1559067at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001694">
        <property type="entry name" value="NADH_UbQ_OxRdtase_su1/FPO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018086">
        <property type="entry name" value="NADH_UbQ_OxRdtase_su1_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00146">
        <property type="entry name" value="NADHdh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00667">
        <property type="entry name" value="COMPLEX1_ND1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="69"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="110"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="181"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="233"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="257"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="295"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ39258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="317" mass="34778" checksum="3ACAF99D285C74DD" modified="2010-01-19" version="1">MSPLEMPSAGWIILAVVQALLMLLLTPLVTGFSRVIRAKIHSRKGPGILQDYRDIMKLLRRQSVAPSNAGMIFWLMPWVLIITMLLIAMALPTVTQTSPFPISGDLITDIYLLAIFRFFFALAGIDSNSMFGGLGSSRELTLGILVEPILILAILLVALAMGTTDLGYISRAMATQTWHQPLTLILAGIVCAFALFIEMGKLPFDSAEAEQELQEGPVTEYSGSNLALVKLGLGLKQLVVAQLFLAIFIPWGKASSLTFTGLFSATVILLIKLFVIFLIAGIAENTMARFRFMKIHRAIFPMFLVAVIALLFFILGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z465</accession>
    <name>D0Z465_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000321</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000321"/>
    <dbReference type="EnsemblBacteria" id="EEZ39303">
        <property type="protein sequence ID" value="EEZ39303"/>
        <property type="gene ID" value="VDA_000321"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5030JUA">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="401" mass="44578" checksum="3DC1454C2B109756" modified="2010-01-19" version="1">MTLSFCGTSCTRDEGEVSRSDSNKDIYLPSTGYIPVRLMKELGGLGVSVRGVGQNDWAMNGTSEKLHVAGQLKASPKLLSYIQSYISGDQYSLIEAARGSSMPALALHGANIAAASKAETINMIGHSRGACEAIMAAWFLYAYVDETVRNTPVNIFAIEPVPGPGEWYGLLTQLPPNVVNYVGIYAWDMCGSKTEHAFQAVVPRPNGRMRGENNDIELHNQSWRNWFKGQSDWSVMADDAQQKDPLAPDDTAPQPQGYELYVCRGRHSTMAGNTTAGAQYDPTKDSTNVAPAPELIYKVARGYLTQWGSQFKASCAVKEDVLELRQHIHRFHREFDMMGGGYIRTSSLPNRPYVRRVSSIYGYNPLNNYYLEDVVGMPPYKLSYPLTSERQGKGWVDWKFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4C5</accession>
    <name>D0Z4C5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative deoxyribonucleoside kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000381</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304207.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000381"/>
    <dbReference type="EnsemblBacteria" id="EEZ39363">
        <property type="protein sequence ID" value="EEZ39363"/>
        <property type="gene ID" value="VDA_000381"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1428">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1275854at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019136">
        <property type="term" value="F:deoxynucleoside kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002624">
        <property type="entry name" value="DCK/DGK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031314">
        <property type="entry name" value="DNK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01712">
        <property type="entry name" value="dNK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000705">
        <property type="entry name" value="DNK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="dNK" evidence="3">
        <location>
            <begin position="9"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="89"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="13"/>
            <end position="21"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="149"/>
            <end position="153"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000705-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000705-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="220" mass="24813" checksum="EEEB709BFC089EB4" modified="2010-01-19" version="1">MTSIKPTIICIEGNIGSGKSTLLPKLAAILQATPILEPADTDPEFQRLLGLFSHNPSDVHARNNFQRYITSQRANLLKGLDSDGLYIIERSLLSDLVFTHACMSNYENTPEDAATHMDCYKHLIAKIHDYPTIDYCIYLKTDPSVAFKRMKQRGREEESSLTLDYLTDISAFHDAVLPQVCRKMGTQLIEINWDNPESLHNLVEKLRSLQLPLVPMANIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4F2</accession>
    <name>D0Z4F2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DNA-binding response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_000408</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304285.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000408"/>
    <dbReference type="EnsemblBacteria" id="EEZ39390">
        <property type="protein sequence ID" value="EEZ39390"/>
        <property type="gene ID" value="VDA_000408"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1020672at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="2"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="125"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="125"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ39390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="229" mass="25896" checksum="2E6723B1BAD92BAC" modified="2010-01-19" version="1">MRILLVEDHHDTAGIIFDYFEIKGAVLDHAATGPRGLALAKEQHYDLIILDLMLPKMDGLTVCRELRDYGIDTPVLMLTAMDSREDILAGFQNGADDYLVKPFDLEILEARVKALTRRRSGMVASNTLVFGELSLDVKTHTAYRKSCKFALNPSLFTILRLLMTRAPQVVTKDELVTALWGDDEPDSNVLRSHLYQLRNLIDKPFEHAYIQTLPKVGYQLVTPEVSHED</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4Y4</accession>
    <name>D0Z4Y4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fido domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_000217</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306634.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000217"/>
    <dbReference type="EnsemblBacteria" id="EEZ39201">
        <property type="protein sequence ID" value="EEZ39201"/>
        <property type="gene ID" value="VDA_000217"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3177">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1232677at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003812">
        <property type="entry name" value="Fido"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036597">
        <property type="entry name" value="Fido-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040198">
        <property type="entry name" value="Fido_containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13504">
        <property type="entry name" value="PTHR13504"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02661">
        <property type="entry name" value="Fic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140931">
        <property type="entry name" value="SSF140931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51459">
        <property type="entry name" value="FIDO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fido" evidence="4">
        <location>
            <begin position="112"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="194"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="238"/>
            <end position="239"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for autoinhibition of adenylyltransferase activity" evidence="3">
        <location>
            <position position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR640198-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR640198-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR640198-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="382" mass="44155" checksum="79E258A654E091C7" modified="2010-01-19" version="1">MTEPNFKDFDLRLVNPSFEMDLTDTLIELDHLRKLRLRGTTAPWIFFQLKEIFHLLESVGSARIEGNRTTISEYVEQKIDSKERSSERFSEIANVEEAMTFIEESIKEGTEITNYFVRQLHELAVRGLTDEGDRTPGQYRQVGVQISQSTHLPPDWVNVQSYMDELIGFINRPDSSKYDLLKTALVHHRFTWIHPFGNGNGRVVRLLTYALLIKYGFNVKEGKLINPTAVFCNDREEYYANLTEADKGTDESLLGWCDYVLSGILGEVKKVNQLLDFDYLSKSILIPTIEHGVDRGYLNKIESEILKVGIKLQKFQASDLDITLAELSPRQRTHQVKKMKDSGFIRPLKENGRTYYVNFMNNFLMRGLIQTLEKEKFIPPID</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4Z0</accession>
    <name>D0Z4Z0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hydrophilic protein virA protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000223</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the phosphothreonine lyase family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306650.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39207">
        <property type="protein sequence ID" value="EEZ39207"/>
        <property type="gene ID" value="VDA_000223"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5030P0H">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1181661at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003519">
        <property type="entry name" value="OspF/SpvC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038498">
        <property type="entry name" value="OspF/SpvC_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03536">
        <property type="entry name" value="VRP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="233" mass="26088" checksum="E2BC9F854ABD63A0" modified="2010-01-19" version="1">MPRLKLNLPPLVVSQNTPPPAPKVSHELKKEDVGKLIKDIEAQPKSSFRNADIHGSYHELSQGGYKNEFSGYKLSNVPFGDVFIHANKDNESREYLGDKIHISIDKAQLSSGFDDILPILLSEDSPIDKWKVTDLNRCPPDSRVAVGAQITLYVKADKESGYVPAELKKVKDFLEQIELTLGQSNTTPGEKPQSDISAANWNFISYRNEYRSDREGGASHQLFEEPFFQVISS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5B3</accession>
    <name>D0Z5B3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PefA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000005">
        <property type="protein sequence ID" value="EEZ39035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005307041.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000005.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000020"/>
    <dbReference type="EnsemblBacteria" id="EEZ39035">
        <property type="protein sequence ID" value="EEZ39035"/>
        <property type="gene ID" value="VDA_000020"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3539">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="951513at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009289">
        <property type="term" value="C:pilus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1090">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036937">
        <property type="entry name" value="Adhesion_dom_fimbrial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008966">
        <property type="entry name" value="Adhesion_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49401">
        <property type="entry name" value="SSF49401"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003020051" evidence="1">
        <location>
            <begin position="23"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="179" mass="18116" checksum="4916A130CDA59BEA" modified="2010-01-19" version="1">MKKTILALTALASLGMVSSAMAAPGNVGTIRFIGSITDTTCDFTGEQGGAQSNVVNLGTHTTAVVNGATGSPVVDFSLVGTKPDGSACEISSSVDVSWVPASGSWTASGLLNTGTATNTVVKLMDKNNKVFNALYETVNYVASDAPKGQLPFKANIMNTGTNATAGTVVSAAKFAVAYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5H6</accession>
    <name>D0Z5H6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000083</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000006">
        <property type="protein sequence ID" value="EEZ39028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005307184.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000006.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000083"/>
    <dbReference type="EnsemblBacteria" id="EEZ39028">
        <property type="protein sequence ID" value="EEZ39028"/>
        <property type="gene ID" value="VDA_000083"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1450">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1297593at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="486" mass="52517" checksum="2ABE9261CEC79425" modified="2010-01-19" version="1">MQFIRTKVAILVSITLLQGCVSQSYLDNKKQAEQLQQHMDEIRPTGVLANVESISRPPINITPIETEHAIAWLNDNIHVQVSGLPLSLVLDTVLKGTGAQVIFSSDVRANTPVSINADTTRQNILNLLSSQTGYGFAPSEHSLSVQRYLTETFMINLPTGTITSQQGSQGETKGEGENTKVEGQFINAAIESQNAFNEIANAIKVVLKSDSEDNKLIGDVQSVPSMGSITVRTTPSRMAQVRQVVDKFQQELAKQVLLEITVLEFRSNLGKDQGIDWQLLKNVGDGTIKFLIPGTTATATGNPAGLAFTGTGKWDGTTAFIKALEEQGTVSTQTPISMLTISGYPARISQTITTPYLSDVSTEVTETTTSTSTTRDKVVEGVDMMVNAKVQKGVVSLRVTGKLTKIAGDTTEKINDATLRFIKTRDADLSFVNKLRYGQTVVIGSIKQQSTGANKSSSFGIDGLGMQSTTNETVETLVLLTPRRTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVV0</accession>
    <name>D0YVV0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">LrgA-associated membrane protein LrgB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_002031</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299226.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002031"/>
    <dbReference type="EnsemblBacteria" id="EEZ40999">
        <property type="protein sequence ID" value="EEZ40999"/>
        <property type="gene ID" value="VDA_002031"/>
    </dbReference>
    <dbReference type="GeneID" id="57341825"/>
    <dbReference type="eggNOG" id="COG1346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1416872at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005261">
        <property type="entry name" value="CHP00659"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007300">
        <property type="entry name" value="CidB/LrgB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30249">
        <property type="entry name" value="PTHR30249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04172">
        <property type="entry name" value="LrgB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00659">
        <property type="entry name" value="TIGR00659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="56"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="85"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="135"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="201"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="226" mass="24301" checksum="8CD94FBE90907E79" modified="2010-01-19" version="1">MIWLVATLVCFYVARYISGKIKNPLLNPLLITLIVLIVLLKWLQVPYEVYFADNKIINFLLGPAVVALALPLYQQLAHIRSKWKTIMTACFVGSVLSMTFGTAIAFWMGADAQLAASILPKSITTPLAMAASQQIGGIPSITAAMVILVGIFGAVLGYPIMKLLKIEHPLAKGLSMGTVSHALGTAKAAEEDYQEGAFSSLALVICGIMTTILAPILFPILVHLFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW17</accession>
    <name>D0YW17_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein-L-isoaspartate O-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.77</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">L-isoaspartyl protein carboxyl methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Protein L-isoaspartyl methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Protein-beta-aspartate methyltransferase</fullName>
            <shortName evidence="2">PIMT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pcm</name>
        <name evidence="3" type="ORF">VDA_001277</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>[protein]-L-isoaspartate + S-adenosyl-L-methionine = [protein]-L-isoaspartate alpha-methyl ester + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:12705"/>
            <dbReference type="Rhea" id="RHEA-COMP:12143"/>
            <dbReference type="Rhea" id="RHEA-COMP:12144"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90596"/>
            <dbReference type="ChEBI" id="CHEBI:90598"/>
            <dbReference type="EC" id="2.1.1.77"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.77" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297770.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001277"/>
    <dbReference type="EnsemblBacteria" id="EEZ40255">
        <property type="protein sequence ID" value="EEZ40255"/>
        <property type="gene ID" value="VDA_001277"/>
    </dbReference>
    <dbReference type="GeneID" id="57339834"/>
    <dbReference type="eggNOG" id="COG2518">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1948290at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004719">
        <property type="term" value="F:protein-L-isoaspartate (D-aspartate) O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030091">
        <property type="term" value="P:protein repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00090">
        <property type="entry name" value="PIMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000682">
        <property type="entry name" value="PCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11579">
        <property type="entry name" value="PTHR11579"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00080">
        <property type="entry name" value="pimt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01279">
        <property type="entry name" value="PCMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <feature type="active site" evidence="2">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="209" mass="23124" checksum="1DA375A6A9B8474A" modified="2010-01-19" version="1">MRYLSERHSLVAFLRNKGIDNERVLHAIAAVPRERFVDEAFSYQAYENNALPIGHGQTISQPYMVARMTSLLELEPSSSVLEIGTGSGYQTAVLAHLVDHVCSVERIKVLQWQAKRRLKSLDLHNVSTKHGDGWQGWANRGPFDAIIVTAAPECVPSDLLAQLADGGRLVLPVGEDSQVLKKIVRIGDRFVHHSIEAVRFVPLIAGELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW77</accession>
    <name>D0YW77_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)</fullName>
            <ecNumber evidence="4">2.5.1.31</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Ditrans,polycis-undecaprenylcistransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Undecaprenyl diphosphate synthase</fullName>
            <shortName evidence="4">UDS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Undecaprenyl pyrophosphate synthase</fullName>
            <shortName evidence="4">UPP synthase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">uppS</name>
        <name evidence="5" type="ORF">VDA_001362</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(2E,6E)-farnesyl diphosphate + 8 isopentenyl diphosphate = di-trans,octa-cis-undecaprenyl diphosphate + 8 diphosphate</text>
            <dbReference type="Rhea" id="RHEA:27551"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58405"/>
            <dbReference type="ChEBI" id="CHEBI:128769"/>
            <dbReference type="ChEBI" id="CHEBI:175763"/>
            <dbReference type="EC" id="2.5.1.31"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="4">Binds 2 magnesium ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the UPP synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.31" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297922.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001362"/>
    <dbReference type="EnsemblBacteria" id="EEZ40337">
        <property type="protein sequence ID" value="EEZ40337"/>
        <property type="gene ID" value="VDA_001362"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1630604at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008834">
        <property type="term" value="F:di-trans,poly-cis-decaprenylcistransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00475">
        <property type="entry name" value="Cis_IPPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01139">
        <property type="entry name" value="ISPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001441">
        <property type="entry name" value="UPP_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018520">
        <property type="entry name" value="UPP_synth-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036424">
        <property type="entry name" value="UPP_synth-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10291">
        <property type="entry name" value="PTHR10291"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01255">
        <property type="entry name" value="Prenyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64005">
        <property type="entry name" value="SSF64005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00055">
        <property type="entry name" value="uppS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01066">
        <property type="entry name" value="UPP_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0133">Cell shape</keyword>
    <keyword evidence="4" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 4" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4 5" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="25"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="69"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="198"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="24"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="72"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="24"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="29"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="37"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="254" mass="28617" checksum="9CD72E31DAC0F9A3" modified="2010-01-19" version="1">MAEQMIETELCADSLPKHIAIIMDGNGRWAQAKGKARVFGHKAGVEAVRKAVSTANRLGIKAVTLFAFSSENWRRPEDEVSLLMELFITVLGREVKRLHKNSIKLKILGDKSRFSQRLQDKIASAEALTENNTGMVLNVAANYGGQWDILQATKKAMQKLIEQGLEPDSMTEEMISAELSTAGEPDVDLLIRTSGECRISNFMLWQTAYAELYFTEQHWPDFDEQSLTDAIAWFVTRERRFGCTGEQIKALMQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW95</accession>
    <name>D0YW95_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-acetylmuramoyl-L-alanine amidase AmpD</fullName>
            <ecNumber evidence="2">3.5.1.28</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001192</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.5.1.28" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297607.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001192"/>
    <dbReference type="EnsemblBacteria" id="EEZ40170">
        <property type="protein sequence ID" value="EEZ40170"/>
        <property type="gene ID" value="VDA_001192"/>
    </dbReference>
    <dbReference type="GeneID" id="57339953"/>
    <dbReference type="eggNOG" id="COG3023">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1584918at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008745">
        <property type="term" value="F:N-acetylmuramoyl-L-alanine amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009253">
        <property type="term" value="P:peptidoglycan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06583">
        <property type="entry name" value="PGRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036505">
        <property type="entry name" value="Amidase/PGRP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002502">
        <property type="entry name" value="Amidase_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01510">
        <property type="entry name" value="Amidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00644">
        <property type="entry name" value="Ami_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55846">
        <property type="entry name" value="SSF55846"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetylmuramoyl-L-alanine amidase" evidence="1">
        <location>
            <begin position="19"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="192" mass="21479" checksum="6477A81B96BC72A9" modified="2010-01-19" version="1">MSLSINSTHWLNEAQHLPSPFYDTRPDGTDISLLVVHNISLPPGEFGGPYVEQLFTGQLDPEAHPYFATIYKLRVSAHCFIRRDGSIIQFVPFNGRAWHAGVSQFAGRDKCNDFSIGIELEGTDTLPFTQAQYDSLIELTRVIMQTYPAIDTSTITGHEFIAPGRKTDPGLVFDWVKYKSALLVSDQDNELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWB5</accession>
    <name>D0YWB5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001378</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40353">
        <property type="protein sequence ID" value="EEZ40353"/>
        <property type="gene ID" value="VDA_001378"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG50339TV">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025346">
        <property type="entry name" value="DUF4250"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14056">
        <property type="entry name" value="DUF4250"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="54" mass="6342" checksum="661242E78F5DF697" modified="2010-01-19" version="1">MDPIMLMSIVNMKIRDEFGDLDSLVKFYDIDKDKLIEKLANAGFDYLPEAKQFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWC1</accession>
    <name>D0YWC1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Methionine ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_001384</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297975.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001384"/>
    <dbReference type="EnsemblBacteria" id="EEZ40359">
        <property type="protein sequence ID" value="EEZ40359"/>
        <property type="gene ID" value="VDA_001384"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1135">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1058434at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009276">
        <property type="term" value="C:Gram-negative-bacterium-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033232">
        <property type="term" value="F:ABC-type D-methionine transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03258">
        <property type="entry name" value="ABC_MetN_methionine_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026253">
        <property type="entry name" value="ABC_MetN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012692">
        <property type="entry name" value="ABC_MetN_proteobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041701">
        <property type="entry name" value="MetN_ABC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018449">
        <property type="entry name" value="NIL_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43166:SF5">
        <property type="entry name" value="PTHR43166:SF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09383">
        <property type="entry name" value="NIL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00930">
        <property type="entry name" value="NIL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02314">
        <property type="entry name" value="ABC_MetN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="5 7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="2"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="107"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ40359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="344" mass="37650" checksum="2119AD23FF6612F8" modified="2010-01-19" version="1">MIEINNVNKIFYQGDKAISALRDINLTIEQGNIFGVIGSSGAGKSTLIRCVNLLERPTSGDIIVDGIKLTQLSNQQLTLARRKIGMIFQHFNLLASRTVFANVALPLELAGVKKNQLENKVNKLLELVGLSEKKHSFPANLSGGQKQRVAIARALASDPKVLLCDEATSALDPATTQSILQLLKKINRQLNITILLITHEMDVVKSICHQVAIIGDGELVEKGPVGDIFAHPKTELARNFIRSTLDLSIPEDYQARMSLEQREGSYPLVRLEFTGDSVDAPLISQVAREFNIDISILSADMDYAGGVKFGLMLAEFFGTETAANKAIAFLRDHKINVEVLGYVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWE1</accession>
    <name>D0YWE1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Putative beta-barrel assembly-enhancing protease</fullName>
            <ecNumber evidence="8">3.4.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">VDA_001412</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the peptidase M48 family. BepA subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298019.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001412"/>
    <dbReference type="EnsemblBacteria" id="EEZ40386">
        <property type="protein sequence ID" value="EEZ40386"/>
        <property type="gene ID" value="VDA_001412"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4783">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1445800at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061077">
        <property type="term" value="P:chaperone-mediated protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00997">
        <property type="entry name" value="Protease_BepA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030873">
        <property type="entry name" value="Protease_BepA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 8 11" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4 8" id="KW-0574">Periplasm</keyword>
    <keyword evidence="1 8 11" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0732">Signal</keyword>
    <keyword evidence="9" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="6 8" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5009009102" description="Putative beta-barrel assembly-enhancing protease" evidence="8">
        <location>
            <begin position="28"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M48" evidence="10">
        <location>
            <begin position="73"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="9">
        <location>
            <begin position="428"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="137"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="205"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ40386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="487" mass="54729" checksum="CBDA4BB28E248129" modified="2010-01-19" version="1" precursor="true">MFRLKKAPVYTLITSLLLGSVPNIALASNSIMLPDMGTTAASTLTIDKELEYGDAYMRMLRSSKPIINDPVLTEYVQDLGHKLVANASDVRTPFTFFLIRDKEINAFAFFGGHVAIHSGLFLYAQNESELASVLAHEIAHVTQRHLARSMEEQAKRSPATMAALVGSLMLAIASPEAGIAAMQATTAASMQGQINYTRSNEKEADRIGIATLAKAGFDPKAMPRFFERLADQYRYVSKPPQMLLTHPLPESRITDSRQRASQYPTVRLPPSENYLLARSRIVARYANFSENAALAWFGHQLKKFPAQRKELNYGKALVYIDNGKYKEANGLLTPLLAAEPNNPFYIDAMTDLDLYQQKFTPAIQRLKTAIEQNPDSTVLRLNYINVLQEQGKYQQTIPLLVRYTYDQPDDINGWSMLAKAFAKTRQRPSELAALAEIYALRAQWDKAITNYMQASQLAPLNSMDQARFDARIDQLRRAKMTFDNLKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWG5</accession>
    <name>D0YWG5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Peptidoglycan glycosyltransferase MrdB</fullName>
            <shortName evidence="9">PGT</shortName>
            <ecNumber evidence="9">2.4.1.129</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Cell elongation protein RodA</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Cell wall polymerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Peptidoglycan polymerase</fullName>
            <shortName evidence="9">PG polymerase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">mrdB</name>
        <name evidence="9" type="synonym">rodA</name>
        <name evidence="10" type="ORF">VDA_001424</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Peptidoglycan polymerase that is essential for cell wall elongation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>[GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-di-trans,octa-cis-undecaprenyl diphosphate + beta-D-GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate = [GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-di-trans-octa-cis-undecaprenyl diphosphate + di-trans,octa-cis-undecaprenyl diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23708"/>
            <dbReference type="Rhea" id="RHEA-COMP:9602"/>
            <dbReference type="Rhea" id="RHEA-COMP:9603"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58405"/>
            <dbReference type="ChEBI" id="CHEBI:60033"/>
            <dbReference type="ChEBI" id="CHEBI:78435"/>
            <dbReference type="EC" id="2.4.1.129"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="9">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell inner membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the SEDS family. MrdB/RodA subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.129" evidence="9"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298036.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001424"/>
    <dbReference type="EnsemblBacteria" id="EEZ40398">
        <property type="protein sequence ID" value="EEZ40398"/>
        <property type="gene ID" value="VDA_001424"/>
    </dbReference>
    <dbReference type="GeneID" id="57339651"/>
    <dbReference type="eggNOG" id="COG0772">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1133883at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008955">
        <property type="term" value="F:peptidoglycan glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02079">
        <property type="entry name" value="PGT_RodA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018365">
        <property type="entry name" value="Cell_cycle_FtsW-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001182">
        <property type="entry name" value="FtsW/RodA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011923">
        <property type="entry name" value="RodA/MrdB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30474">
        <property type="entry name" value="PTHR30474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30474:SF1">
        <property type="entry name" value="PTHR30474:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01098">
        <property type="entry name" value="FTSW_RODA_SPOVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02210">
        <property type="entry name" value="rodA_shape"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00428">
        <property type="entry name" value="FTSW_RODA_SPOVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 9" id="KW-0133">Cell shape</keyword>
    <keyword evidence="8 9" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="2 9" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="139"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="163"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="186"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="275"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="308"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="341"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ40398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="373" mass="40837" checksum="89E71B54611C9465" modified="2010-01-19" version="1">MSIMAETGNKRTLSDRLHIDVPLLLGLLTLMGFALVIMWSASGQNLPMMERQGMRILLSLAIMFALAQVPPRHYEAWAPYLFGVGLVLLVGVLAFGEVSKGAQRWLNLGFVRFQPSELIKLAVPLMVARFIGNRPLPPSFRNLVIALVMIFVPTILIAKQPDLGTSILIAASGIFVLFLSGISWRIILAACLLLGAFVPILWFFLMHDYQRTRVMTLFNPESDPLGAGYHIIQSKIAIGSGGLHGKGWLHGTQSQLEFVPERHTDFIFAVIAEEWGLLGVLFLLGVYLFIIGRGLLLASRAQTAFGRMMAGSIVLSFFVYVFVNIGMVSGILPVVGVPLPLVSYGGTSMVTLMAGFGILMSIHTHRKMLSKAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWP0</accession>
    <name>D0YWP0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N-acetylmuramoyl-L-alanine amidase</fullName>
            <ecNumber evidence="2">3.5.1.28</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001526</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides.</text>
            <dbReference type="EC" id="3.5.1.28"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="3.5.1.28" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298219.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001526"/>
    <dbReference type="EnsemblBacteria" id="EEZ40500">
        <property type="protein sequence ID" value="EEZ40500"/>
        <property type="gene ID" value="VDA_001526"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0860">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1184688at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008745">
        <property type="term" value="F:N-acetylmuramoyl-L-alanine amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009253">
        <property type="term" value="P:peptidoglycan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02696">
        <property type="entry name" value="MurNAc-LAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002508">
        <property type="entry name" value="MurNAc-LAA_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01520">
        <property type="entry name" value="Amidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00646">
        <property type="entry name" value="Ami_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MurNAc-LAA" evidence="3">
        <location>
            <begin position="76"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="211" mass="24078" checksum="CC7C8311DF3C5851" modified="2010-01-19" version="1">MKQPLFILDAGHGGIINGQYQTAGKRSPIWDDGSQLFEGEFNRAVVAGISQQLAQRNIKHHILVPEQRDIHLRDRVRRANRLAKHYSRYQCILISVHANAGGGSGFEVFTSKGKTRSDDIADHFALAFKDVFPNKPLRADLRDGDYDKDRSFYILRYTSMPAILTENFFMDNEQECKEILMTSTGREMVVKYHVEGIRRILGECPEFCVTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWP6</accession>
    <name>D0YWP6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribose-phosphate pyrophosphokinase</fullName>
            <shortName evidence="6">RPPK</shortName>
            <ecNumber evidence="6">2.7.6.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">5-phospho-D-ribosyl alpha-1-diphosphate</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Phosphoribosyl diphosphate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Phosphoribosyl pyrophosphate synthase</fullName>
            <shortName evidence="6">P-Rib-PP synthase</shortName>
            <shortName evidence="6">PRPP synthase</shortName>
            <shortName evidence="6">PRPPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">prs</name>
        <name evidence="8" type="ORF">VDA_001442</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>ATP + D-ribose 5-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15609"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.6.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="6">Binds 2 Mg(2+) ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Metabolic intermediate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route I): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.6.1" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001442"/>
    <dbReference type="EnsemblBacteria" id="EEZ40416">
        <property type="protein sequence ID" value="EEZ40416"/>
        <property type="gene ID" value="VDA_001442"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0462">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00087">
        <property type="reaction ID" value="UER00172"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004749">
        <property type="term" value="F:ribose phosphate diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006015">
        <property type="term" value="P:5-phosphoribose 1-diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009165">
        <property type="term" value="P:nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009156">
        <property type="term" value="P:ribonucleoside monophosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00583_B">
        <property type="entry name" value="RibP_PPkinase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000842">
        <property type="entry name" value="PRib_PP_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029099">
        <property type="entry name" value="Pribosyltran_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005946">
        <property type="entry name" value="Rib-P_diPkinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037515">
        <property type="entry name" value="Rib-P_diPkinase_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10210">
        <property type="entry name" value="PTHR10210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14572">
        <property type="entry name" value="Pribosyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13793">
        <property type="entry name" value="Pribosyltran_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01251">
        <property type="entry name" value="ribP_PPkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00114">
        <property type="entry name" value="PRPP_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran_N" evidence="7">
        <location>
            <begin position="4"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Ribose-5-phosphate binding" evidence="6">
        <location>
            <begin position="224"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="194"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="37"/>
            <end position="39"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="96"/>
            <end position="97"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ40416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="315" mass="34338" checksum="A51AB4B6E72E22B4" modified="2010-01-19" version="1">MPDMKLFAGNATPELAQRIADRLYISLGDATVNRFSDGEVCVQINENVRGSDVFIIQSTCAPTNDNLMELVVMIDALRRASAGRITAVIPYFGYARQDRRVRSARVPITAKVVADFLSNVGVDRVLTVDLHAEQIQGFFDVPVDNVFGSPVLLEDMLTKDLDDPVVVSPDIGGVVRARAIAKLLDDTDIAIIDKRRPRANVSQVMHLIGDVEGRDCIIVDDMIDTGGTLCKAAEALKERGAKRVFAYATHPVFSGTAAQNIRESVIDEVIVTDSIPLQKELAETGKVSVLTLSGMLAEAIRRISNEESISAMFEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-12-02" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWW6</accession>
    <name>D0YWW6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hypothetical lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001799</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298723.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40767">
        <property type="protein sequence ID" value="EEZ40767"/>
        <property type="gene ID" value="VDA_001799"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031CW0">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043724">
        <property type="entry name" value="DUF5666"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18914">
        <property type="entry name" value="DUF5666"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5666" evidence="1">
        <location>
            <begin position="170"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="226" mass="24189" checksum="86403BE21C2F7AEF" modified="2010-01-19" version="1">MEKLTLAVALSLLLSACGDKAPAPEQTKSAPQPITHASGVLTAASAGEYTLTLDGKTYNTEQANVDYEGQDFNLDSVHKGMNVTLTIQGKNVTDIELDPAFSGLAVLNNDNQLVMNGTKVTITDPEVFSLDYKNGGGDLGWVLVSAHLDNNKWVVTNVSPVNNMPNSEVEGKVSDLTDSSFMLGTTKVMYQANTITDSKKLANGMYVQAIGVFNNDTLTVNRIDVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWX0</accession>
    <name>D0YWX0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4 6">Integration host factor subunit beta</fullName>
            <shortName evidence="4">IHF-beta</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ihfB</name>
        <name evidence="4" type="synonym">himD</name>
        <name evidence="7" type="ORF">VDA_001803</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 6">This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 6">Heterodimer of an alpha and a beta chain.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the bacterial histone-like protein family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298731.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001803"/>
    <dbReference type="EnsemblBacteria" id="EEZ40771">
        <property type="protein sequence ID" value="EEZ40771"/>
        <property type="gene ID" value="VDA_001803"/>
    </dbReference>
    <dbReference type="GeneID" id="57342082"/>
    <dbReference type="eggNOG" id="COG0776">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1847472at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00381">
        <property type="entry name" value="IHF_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000119">
        <property type="entry name" value="Hist_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020816">
        <property type="entry name" value="Histone-like_DNA-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010992">
        <property type="entry name" value="IHF-like_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005685">
        <property type="entry name" value="IHF_beta"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33175">
        <property type="entry name" value="PTHR33175"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00216">
        <property type="entry name" value="Bac_DNA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01727">
        <property type="entry name" value="DNABINDINGHU"/>
    </dbReference>
    <dbReference type="SMART" id="SM00411">
        <property type="entry name" value="BHL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47729">
        <property type="entry name" value="SSF47729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00988">
        <property type="entry name" value="hip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00045">
        <property type="entry name" value="HISTONE_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="3 4 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4 6" id="KW-0810">Translation regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="95" mass="10791" checksum="F961CAB7597B9252" modified="2010-01-19" version="1">MTKSELIERLCSQQTHLSAKQVEDAIKEILEQMATTLEQGERIEIRGFGSFSLHFRAPRVGRNPKTGDKVELDGKYVPHFKPGKELRDRVNAQVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWZ0</accession>
    <name>D0YWZ0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hypothetical enzyme of sugar metabolism</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001823</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298774.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001823"/>
    <dbReference type="EnsemblBacteria" id="EEZ40791">
        <property type="protein sequence ID" value="EEZ40791"/>
        <property type="gene ID" value="VDA_001823"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0451">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1558163at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="9"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="282" mass="31248" checksum="65F43E654331F6B3" modified="2010-01-19" version="1">MKVSICGCGWLGEPLALHLLDLGYEVFGSKTSQDGVNKIRQRGINCCEISVPLDNNSDYPYFCEDKDKRAFFATDVLVINVPPKLRSSDKQSHIHNIKTLMTAAEYHGCKRIIFISTTAVYGDTKGRVTESTKPRPQTESGKAHLEIERQLLDTWPDRSTILRLSGLIGPNRHPVKFLSGRKDIEKGSDPVNLIHLTDCIAAISRIIAKQPPSPILHLAANSHPSRASYYTQMAELAKLPLPNFSLSPDSHENGKWIDASMTLKALDLTLVHSDLISLAPEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX11</accession>
    <name>D0YX11_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Major tail sheath protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002059</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299309.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002059"/>
    <dbReference type="EnsemblBacteria" id="EEZ41027">
        <property type="protein sequence ID" value="EEZ41027"/>
        <property type="gene ID" value="VDA_002059"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3497">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="558210at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="391" mass="42585" checksum="4B31B0F1DF55E8FB" modified="2010-01-19" version="1">MSSLTPIQDFELNGVEVHTIEPQPSMGPLAQQVVHLVGTAPDKRGTVAYHEPTRLWNYSDAMMALDSTGNRQGTLPHVVRYLLEYVKCILYVTVVPVGDNSAATEANVIGGVDSSTGAIRGLETIKACPETPTVIAAPGFHSKAVGQALALIGRDVRCRPVLDGPNSNDMAAAEFASGFGAEGTGEDKLCIIDPWFMKTYDGAQVLMPASIALVAAMASVAGWESPQNRAVLCDETARNVSYKINDKTTQANFLNKHGVTTIAHTRMGGYSIIGNRTNTGRFISHVGLEDLMARKLEETSQPLLGKQLTEDFMQQVVDRLTNWGQDLVAQKVIPVFKAFLHPSKNNLENYTAGRWFLCVNYGRYSPNEHMIYEMSVDNGLIAAWLEEVLNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX57</accession>
    <name>D0YX57_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001846</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298805.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001846"/>
    <dbReference type="EnsemblBacteria" id="EEZ40814">
        <property type="protein sequence ID" value="EEZ40814"/>
        <property type="gene ID" value="VDA_001846"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3417">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1513163at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014094">
        <property type="entry name" value="LpoB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40593">
        <property type="entry name" value="PTHR40593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13036">
        <property type="entry name" value="LpoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02722">
        <property type="entry name" value="lp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019789" evidence="2">
        <location>
            <begin position="23"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="219" mass="23972" checksum="3956BF55432E119D" modified="2010-01-19" version="1">MKKHLVAAVGMSALLLGGCAQQVDYGNISDVWNKPETNVPAKPQPKPDTTTPVNPQPKPQPPQQKTDLNEVAENLTENMLASAAVKKITSGAEPVLFVSSMQNKTTSHVNSKQLLNTVKETVDDSGKFASVDSSRVKEVRQQLNFSSDDQLVNQSTAIQFGNMVGAQYMLYGNVSNTNKQVDGQSMPFYRMTMRLMDLKSGLIEWSDKADAPNTNPQGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX70</accession>
    <name>D0YX70_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidyl-prolyl cis-trans isomerase</fullName>
            <ecNumber evidence="4">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_001855</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the FKBP-type PPIase family.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001855"/>
    <dbReference type="EnsemblBacteria" id="EEZ40823">
        <property type="protein sequence ID" value="EEZ40823"/>
        <property type="gene ID" value="VDA_001855"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0545">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="5">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="41" mass="4480" checksum="AA505FB2A01F8326" modified="2010-01-19" version="1">MVEGEKVRLFIPANLAYGNNSAGIIKPGSTLIFDVELFKIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXB9</accession>
    <name>D0YXB9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Serine--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Seryl-tRNA synthetase</fullName>
            <shortName evidence="8">SerRS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Seryl-tRNA(Ser/Sec) synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">serS</name>
        <name evidence="11" type="ORF">VDA_001659</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-serine + tRNA(Sec) = AMP + diphosphate + H(+) + L-seryl-tRNA(Sec)</text>
            <dbReference type="Rhea" id="RHEA:42580"/>
            <dbReference type="Rhea" id="RHEA-COMP:9742"/>
            <dbReference type="Rhea" id="RHEA-COMP:10128"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78533"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>ATP + L-serine + tRNA(Ser) = AMP + diphosphate + H(+) + L-seryl-tRNA(Ser)</text>
            <dbReference type="Rhea" id="RHEA:12292"/>
            <dbReference type="Rhea" id="RHEA-COMP:9669"/>
            <dbReference type="Rhea" id="RHEA-COMP:9703"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78533"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Aminoacyl-tRNA biosynthesis; selenocysteinyl-tRNA(Sec) biosynthesis; L-seryl-tRNA(Sec) from L-serine and tRNA(Sec): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer. The tRNA molecule binds across the dimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.11" evidence="8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298462.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001659"/>
    <dbReference type="EnsemblBacteria" id="EEZ40632">
        <property type="protein sequence ID" value="EEZ40632"/>
        <property type="gene ID" value="VDA_001659"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0172">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="353391at2"/>
    <dbReference type="UniPathway" id="UPA00906">
        <property type="reaction ID" value="UER00895"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004828">
        <property type="term" value="F:serine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016260">
        <property type="term" value="P:selenocysteine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097056">
        <property type="term" value="P:selenocysteinyl-tRNA(Sec) biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006434">
        <property type="term" value="P:seryl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00770">
        <property type="entry name" value="SerRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00176">
        <property type="entry name" value="Ser_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002317">
        <property type="entry name" value="Ser-tRNA-ligase_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015866">
        <property type="entry name" value="Ser-tRNA-synth_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042103">
        <property type="entry name" value="SerRS_1_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033729">
        <property type="entry name" value="SerRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010978">
        <property type="entry name" value="tRNA-bd_arm"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43697">
        <property type="entry name" value="PTHR43697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02403">
        <property type="entry name" value="Seryl_tRNA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001529">
        <property type="entry name" value="Ser-tRNA-synth_IIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00981">
        <property type="entry name" value="TRNASYNTHSER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46589">
        <property type="entry name" value="SSF46589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00414">
        <property type="entry name" value="serS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 11" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="10">
        <location>
            <begin position="173"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="43"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Serine binding" evidence="8">
        <location>
            <begin position="242"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="273"/>
            <end position="275"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="296"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="360"/>
            <end position="363"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="396"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ40632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="436" mass="49040" checksum="0E463A9A1392A08D" modified="2010-01-19" version="1">MLDSKLLRTELDDTAEKLARRGFKLDVENLRQLEEQRKSLQVKTEELQAQRNARSKSIGQAKAKGDHEEAERILAEVGNLGSELDEAKKALAALQAELDAITQTVPNIPDESVPVGKDENDNVEISRWGEPKTYDFEVKDHVDLGEMSDGLDFASAVKITGARFIVMKGQFARLHRAIAQFMLDLHIEEHGYTEMYVPYLVNADSLFGTGQLPKFGADLFHTQPLTEKVNDEEPRTLSLIPTAEVPVTNLMRDTISEEADLPVKMTAHTPCFRSEAGSYGRDTRGLIRMHQFDKVELVQITKPEDSMAALEELTGHAEKVLQLLELPYRKVVLCTGDMGFGSCKTYDLEVWVPAQETYREISSCSNMWDFQARRMQARFRRKGEKKPELVHTLNGSGLAVGRTMVAILENNQEADGRIRIPEVLRKYMNGAEYIGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXH4</accession>
    <name>D0YXH4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Large ribosomal RNA subunit accumulation protein YceD</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">23S rRNA accumulation protein YceD</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001681</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Plays a role in synthesis, processing and/or stability of 23S rRNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DUF177 domain family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001681"/>
    <dbReference type="EnsemblBacteria" id="EEZ40652">
        <property type="protein sequence ID" value="EEZ40652"/>
        <property type="gene ID" value="VDA_001681"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1399">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003772">
        <property type="entry name" value="YceD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039255">
        <property type="entry name" value="YceD_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38099">
        <property type="entry name" value="PTHR38099"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02620">
        <property type="entry name" value="YceD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00031841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="77" mass="8558" checksum="3B9C2A75090C8A1D" modified="2010-01-19" version="1">MNAEDELPEAYEPTQVDENGEINLVELIEDEMILELPQVAMHDDADCNVGSANMSFGEIPVADERPNPFAVLKNLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXH6</accession>
    <name>D0YXH6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Phosphate acyltransferase</fullName>
            <ecNumber evidence="3 4">2.3.1.274</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Acyl-ACP phosphotransacylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Acyl-[acyl-carrier-protein]--phosphate acyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Phosphate-acyl-ACP acyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">plsX</name>
        <name evidence="5" type="ORF">VDA_001683</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>a fatty acyl-[ACP] + phosphate = an acyl phosphate + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:42292"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:14125"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:59918"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:138651"/>
            <dbReference type="EC" id="2.3.1.274"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Lipid metabolism; phospholipid metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer. Probably interacts with PlsY.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="4">Associated with the membrane possibly through PlsY.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PlsX family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.274" evidence="3 4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298508.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001683"/>
    <dbReference type="EnsemblBacteria" id="EEZ40654">
        <property type="protein sequence ID" value="EEZ40654"/>
        <property type="gene ID" value="VDA_001683"/>
    </dbReference>
    <dbReference type="GeneID" id="57342236"/>
    <dbReference type="eggNOG" id="COG0416">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="631784at2"/>
    <dbReference type="UniPathway" id="UPA00085"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043811">
        <property type="term" value="F:phosphate:acyl-[acyl carrier protein] acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00019">
        <property type="entry name" value="PlsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003664">
        <property type="entry name" value="FA_synthesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012281">
        <property type="entry name" value="Phospholipid_synth_PlsX-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30100">
        <property type="entry name" value="PTHR30100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02504">
        <property type="entry name" value="FA_synthesis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002465">
        <property type="entry name" value="Phsphlp_syn_PlsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00182">
        <property type="entry name" value="plsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="4" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="340" mass="36671" checksum="1C190F179C86830C" modified="2010-01-19" version="1">MGLTVALDAMGGDFGPQVTVPAVVQALLHFPELKVTLFGDQSAITTQLTLLNQLNHPRITIVHSNSAIANDARPSQALRRSHGSSMRMALEAVSEGNADACVSAGNTGALMALSRYILKQLPGIDRPALVSAIPTAAATKTWILDLGANVSCDSDTLFQFAVMGAVLAEQWLSGKPRVALLNIGEEEIKGNDLVKRCAEMLSQCDDIDYIGYIEGDKLYSGLADVIVCDGFVGNVSLKTSEGVAHLFIDRIRQAVGTSKFKQILAKWLFSDLFDSLKQLNPDQYNGASLLGLRGIVVKSHGSADITAFTNAISEAVYEVERQIPTKISNRLEEVLLERHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXK7</accession>
    <name>D0YXK7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Periplasmic protein TorT</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001721</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298579.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001721"/>
    <dbReference type="EnsemblBacteria" id="EEZ40692">
        <property type="protein sequence ID" value="EEZ40692"/>
        <property type="gene ID" value="VDA_001721"/>
    </dbReference>
    <dbReference type="GeneID" id="57342194"/>
    <dbReference type="eggNOG" id="COG1879">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1378040at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001761">
        <property type="entry name" value="Peripla_BP/Lac1_sug-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014301">
        <property type="entry name" value="TMAO_TorT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00532">
        <property type="entry name" value="Peripla_BP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02955">
        <property type="entry name" value="TMAO_TorT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019813" evidence="1">
        <location>
            <begin position="19"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="domain" description="Peripla_BP_1" evidence="2">
        <location>
            <begin position="49"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="357" mass="40173" checksum="7AFF5E38ED89844A" modified="2010-01-19" version="1">MRFFCLLALLLTIQPALARSVYSFTPPFADKHQVEEVNIQPLDSVSKPWKICAVYPHLKDSYWLSINYGMVKQAKKLGVDLVVYEAGGYPNLDKQTAQLKRCHEWGADAIILGTVDSQGYNGKLTSLIGNTPVFVMTNDIDMTDPDIKKHVKARVGVDWYYMGQKAGEFLAKRHPKGSGEVKVAWLPGPQRRGGTKPVTRGFMDAIKNSDVHVVTTQWADNSKELQRNLIQQLFVYHPDINYIVGGAVASEVAISELRANHKTNNIKIVSTYLSHGVYRGLRRNKILFSPSDKMVEQAQLSLDQAVRYLEHKPLLKDISPQIESLTPNHLPTTVIKESLSPAEFRPVFEVLNNKIKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXQ3</accession>
    <name>D0YXQ3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Fe-S oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001752</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298630.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001752"/>
    <dbReference type="EnsemblBacteria" id="EEZ40720">
        <property type="protein sequence ID" value="EEZ40720"/>
        <property type="gene ID" value="VDA_001752"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0247">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0277">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1034540at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.45.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004113">
        <property type="entry name" value="FAD-linked_oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016171">
        <property type="entry name" value="Vanillyl_alc_oxidase_C-sub2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02913">
        <property type="entry name" value="FAD-oxidase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13183">
        <property type="entry name" value="Fer4_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="SSF55103"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="4">
        <location>
            <begin position="48"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="1031" mass="115036" checksum="150F2123A8D9780C" modified="2010-01-19" version="1">MLPALSQQEALEPTVLAYLTQLENMGFSGDVETSYASRLTVSTDNSIYQQLPQAVVFPKSLQDLSLLGQVAADPHFQAIRFSPRGGGTGTNGQSLTSGIVVDLSRHLNQILEINIDQQYVRVQTGVIKDQLNDALRPLGYFFSPDLSTSNRATIGGMINTDASGQGSLKYGKTSDHVLGLTAVFADGSILETAPQSPPHYQSPLVEEREEPVETELSFAQQGVQVTAEICAQYRSAIVAKFPPLNRFLTGYDLKHVYNDDLSQFDLTRLLCGAEGSLAFIAEAKLNITPIPKARTLVNIKYDSFDAALRHAPMMVEANALSVETIDSTVLNLAKQDIVWTTVSDLLTDVPNKELLGINMVEYASANEQDNRQQVQLLCQKLDQLMAANQAGIIGYQICDDLASINRIYTMRKKAVGLLGATKGSRKPIAFAEDTCVPPEHLADFIAEFRQLLDSHQLQYGMFGHVDAGVLHVRPALDMCDPAQELLMKQLSDHVVALVAKYGGLMWGEHGKGFRSQYGPEFFGAELFTQLRTIKAAFDPDNRMNPGKICTPLGCDEPLVQVDGLKRGTFDRQIPITTRDSFKQAMECNGNGLCFNYDTSSPMCPSMKVSSDRRHSPKGRAGLVREWLRQLAANGISAEQLEQELLSQKPSVKAIIERWKNSFGSQRHQYDFSHEVMEAMNGCLACKACASQCPIKVDVPSFRSRFMHIYYSRYQRPAKDYLVAHIETMLPVMAKAPSLVNGFIKPNWSKKLTAKTLGYIDTPLLSVPTLAERLDGHHATHFDLTWLQALSETERQNYVLIVQDPFTSFYEAGVVYDFVELIAKLGKKPMLVPFKPNGKAQHIKGFLRQFSQTAANTAEFLNQLAQLNIPMVGVDPALVLCYRDEYKEILAEKRGDFEVKLAHEWLLTILAERQEKPTLIDNQPWYLFAHCTEKTKLPNAEKEWGTIFAHFGLRLESVAVGCCGMAGTFGHEQDKLEISKQVYQLSWQPNIEKLDTDRCLATGYSCRSQVKRFEKIQFKHPVQAILSQLKHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-06-02" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXW4</accession>
    <name>D0YXW4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002127</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299501.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002127"/>
    <dbReference type="EnsemblBacteria" id="EEZ41095">
        <property type="protein sequence ID" value="EEZ41095"/>
        <property type="gene ID" value="VDA_002127"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5032ZGA">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1944349at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021735">
        <property type="entry name" value="DUF3306"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11748">
        <property type="entry name" value="DUF3306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="246" mass="27148" checksum="36ABF2941C970E3E" modified="2010-01-19" version="1">MTSNFFQRWSSRKLTAREETPQVEEKKEDSIEIIDDTVAQSLSNTHIDEANASSESTSPCEQSDTSALDNSVSDNHSSEIDNEVEETEDLTLSDVDKVTFESGAASFLKQGVDKAVKKAALRKLFHSSEYNYISDMDDCTEDFSQLETLSDKVKGELRSWAKEQIDDLLTPEQASDNSQSQAQPAELTKNSVDSSEQLNEQSTDSELSLTTTQTSADSSVESLPTESTQTEDFAAHKATHKPVNKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXX0</accession>
    <name>D0YXX0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002133</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299512.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41101">
        <property type="protein sequence ID" value="EEZ41101"/>
        <property type="gene ID" value="VDA_002133"/>
    </dbReference>
    <dbReference type="GeneID" id="57341736"/>
    <dbReference type="eggNOG" id="ENOG502Z8UG">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1143930at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012544">
        <property type="entry name" value="PHb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037063">
        <property type="entry name" value="PHb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021722">
        <property type="entry name" value="UPF_YvbH_oligomer_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08000">
        <property type="entry name" value="bPH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11724">
        <property type="entry name" value="YvbH_ext"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="bPH_1" evidence="1">
        <location>
            <begin position="10"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="YvbH_ext" evidence="2">
        <location>
            <begin position="145"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="203" mass="23383" checksum="422DF21503AD5088" modified="2010-01-19" version="1">MFKKLASEALGLSDIGKIIAPGDYNKVDSDDYIFHEDNEQIFFLIKSKKDEYCFTNRALIHVDGASAVSSKRVLKRYEYSHYTFRHVLLETAGTIDLDAEIKFQLGEEYFSIDVDKQQIEQLKDLYKALFEIAHQQYLNMVSLDDARKSLELATSAVGRLSSNATPSTEFEKMTQFAFQYIESAKGTYQRSDFTEVFQKFINN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY07</accession>
    <name>D0YY07_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002170</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41138">
        <property type="protein sequence ID" value="EEZ41138"/>
        <property type="gene ID" value="VDA_002170"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031UJJ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="96" mass="10539" checksum="491250EABFDC7608" modified="2010-01-19" version="1">MRITQIEMAKKLGLTQLEFSDILRGSKTIESGFVNDFCNRLGVDPVLTLPSLRQKAVAGMPGSVMLKNTITLDGTVQNVTFSGNQVVIEYEHNIKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY66</accession>
    <name>D0YY66_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Dihydrolipoyl dehydrogenase</fullName>
            <ecNumber evidence="9">1.8.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">VDA_002229</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>(R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + NAD(+) = (R)-N(6)-lipoyl-L-lysyl-[protein] + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:15045"/>
            <dbReference type="Rhea" id="RHEA-COMP:10474"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="EC" id="1.8.1.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="9">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="9">The active site is a redox-active disulfide bond.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.4" evidence="9"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299695.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002229"/>
    <dbReference type="EnsemblBacteria" id="EEZ41197">
        <property type="protein sequence ID" value="EEZ41197"/>
        <property type="gene ID" value="VDA_002229"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0398">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1249">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="267896at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004148">
        <property type="term" value="F:dihydrolipoyl dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006258">
        <property type="entry name" value="Lipoamide_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012999">
        <property type="entry name" value="Pyr_OxRdtase_I_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032816">
        <property type="entry name" value="SNARE_assoc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09335">
        <property type="entry name" value="SNARE_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="SSF55424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01350">
        <property type="entry name" value="lipoamide_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00076">
        <property type="entry name" value="PYRIDINE_REDOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 9" id="KW-0274">FAD</keyword>
    <keyword evidence="3 9" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 9" id="KW-0520">NAD</keyword>
    <keyword evidence="5 9 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8 9" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="49"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="83"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="134"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="164"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="194"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="239"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_2" evidence="12">
        <location>
            <begin position="239"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_dim" evidence="11">
        <location>
            <begin position="583"/>
            <end position="690"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ41197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="717" mass="78483" checksum="36B61CB8B1B97119" modified="2010-01-19" version="1">MDKRKLFLLGIIAAVIGIWLYFDLSQYFTLEQAKAQQLALQDTIQTHPVWASLVFFFAYVAVTALSLPGAAIMTLLGAALFGFWWSLVLVSFASTIGATLAFLFSRFILRDWVQTKFGSRLSAINDGVKKQGSFYLLSLRLIPVFPFFLINLLMGLTPIRAKQFFFVSQLGMLPGTAVYVNAGTQLGEINTLSGIISLPVLISLALLGLFPLIAKAVMNQIQARKIYQKWQKPTSFDQNMVVIGAGSGGLVSAYIAAAVKAEVTLIEKHKMGGDCLNTGCVPSKALIRAAHNMAEIQRAAEFGVSTGPIAIDFKQVMTRVQKVISKIEPHDSIERYRSLGVNCITGEAIIRSPWEVEVAGKIITTKNIVIATGARPLVPNIPGLQSVNYLTSDTVWSQQEQPQKLLVLGGGPIGCELAQSFARLGTKVTLVEMAPQLLIREDSDAAKLVQDSLIADGVEIKLEHKAMRFESIVDANGKIMGKVYLDFHNEQQVTVEFDAVLLALGRVANVQGFGLEELGITTTARGTVEVNDYLQTQYPNIYAVGDVVGPYQLTHAASHQAWYAAVNGLFGQFKRFKADYSVMPAATYTSPEVARVGLNEKEATAQGIEFDVVTYGIDDLDRAITDGEDHGFIKVITPKGKDTILGATIVGTNAGDLLAEFTLAMRHNLGLNKILATVHPYPTMSEAVKYTAGVWKRNNAPEKLLEWVAKYHRWMRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYA4</accession>
    <name>D0YYA4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002267</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299761.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002267"/>
    <dbReference type="EnsemblBacteria" id="EEZ41235">
        <property type="protein sequence ID" value="EEZ41235"/>
        <property type="gene ID" value="VDA_002267"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3650">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1814216at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019841" evidence="1">
        <location>
            <begin position="28"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="239" mass="26448" checksum="FAC37560D99FABDE" modified="2010-01-19" version="1">MKIRTSIVKASYCSAFIVLLLSGCDSAEKAEQANSGLPSSIEARDAFVADIVAKHIYKAGETLPENPNGYPPYIYGTADLNNNGEDEILILMQNQDYCGSGGCTGFVFDNKKQQVAKFTVMDRPILLGNEVHLGWHDIIAYSDGAMHSLRYSADGYPLNTSTAPIFDYETKQKEAVGLAMNSEYYKDNGTNLVPAYQQKIFDCQSCYLFSYDYQDGSDKISYLEVNVDSKKVTPIEAIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYG3</accession>
    <name>D0YYG3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative transcriptional regulator LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002326</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002326"/>
    <dbReference type="EnsemblBacteria" id="EEZ41294">
        <property type="protein sequence ID" value="EEZ41294"/>
        <property type="gene ID" value="VDA_002326"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="271" mass="29524" checksum="3000B78D8F23C40D" modified="2010-01-19" version="1">MSRTGSRLYISQSAVSKRIAKLEAKLGKKLIEPKGRHIKLTPDAELLIANVGPSFNEIRGLIYEQQELTDQTCISLDCSETLVAGYLAPIIGSYIERDPYISITTHHTPVIVEHIQSGEAIIGFCAGHLPPHHGLETIHLLDEPFSIVSKEALLAPPLNLIVNDLKNPANAYQAGLLQQANIIPLMEMDSYTASAQLALAGVAPALVPQSIVSTLNIPTMHCHHFAFLDELTRPIHLLYRANSLKSSRVKTLIETIADAVPKVALTPSTLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYM3</accession>
    <name>D0YYM3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative sohB protein peptidase U7 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_002386</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S49 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002386"/>
    <dbReference type="EnsemblBacteria" id="EEZ41354">
        <property type="protein sequence ID" value="EEZ41354"/>
        <property type="gene ID" value="VDA_002386"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0616">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07023">
        <property type="entry name" value="S49_Sppa_N_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002142">
        <property type="entry name" value="Peptidase_S49"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013703">
        <property type="entry name" value="Peptidase_S49_N_proteobac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01343">
        <property type="entry name" value="Peptidase_S49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08496">
        <property type="entry name" value="Peptidase_S49_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Peptidase_S49_N" evidence="8">
        <location>
            <begin position="2"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S49" evidence="7">
        <location>
            <begin position="148"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="336" mass="36955" checksum="34E5C5E39AC2DF7C" modified="2010-01-19" version="1">MVAVVAILLVVKGIKGHGGSQKGELEVTDLTEQYKETVSQLEEHLFDKSLLKARDKAEKKADKEQEKARQNEVKKAAKEGELDFSRDSRLFVIDFKGGIDAREVSALRQEVTAILAVAQEGDEVLLRLETGGGMVHDYGLASSQLDRLKAAGLKLTISVDKVAASGGYMMACVADKIISAPFAIVGSIGVIAQIPNFNKVLKKNDIEFEQITAGEFKRTLTMFGENTDKAREKFKLEIEETHGLFKDFIANHRPELDLNKVATGEHWFGQQAFELGLVDAIGTSDDFITAACKERKVLGVKYVQRKKLAEKLAGATAEATDSLLLKWVGRGQRPFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYQ0</accession>
    <name>D0YYQ0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002413</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300045.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41381">
        <property type="protein sequence ID" value="EEZ41381"/>
        <property type="gene ID" value="VDA_002413"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502ZBIA">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2126242at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="392" mass="43818" checksum="8C3C225B9F07C903" modified="2010-01-19" version="1">MVFQSDLNEYCQTYLVKKENVPEPSPWSFLRDTEKTNQSNFEQSMLFDRVSFKVYGANIPLIILINKFGVKGVEALLEQDAINFVLWNHMVTYMVDEIKGVEPLQSGTLTSPAHSDPEESLSLGFGWLAKPLRTSSKKNLIRKTRDKYTILDSNLSAKSVQLAKSSYNSGKLKIYGLDPELSSYIDLNKSGREKLCSCASEILLYSYLINNNISTYDNFEFYNIFNESVDKINKSKKVLNNYNVLSKVENIPNAASIYNQLEKPFDKLIKIRNKNNSKKFRKWLSDNSCTDQDITKSYIDSIVNSKGFFETKKGKLTKSIAMTAIGGVIGGAIAGPGGAVGGAGALKLLEPAADIALDMLDEFVLSGLTKGWTPKMYFDDLGKLQNITKTSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYS9</accession>
    <name>D0YYS9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-acetylneuraminate lyase</fullName>
            <ecNumber evidence="2">4.1.3.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002442</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DapA family.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.3" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300099.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002442"/>
    <dbReference type="EnsemblBacteria" id="EEZ41410">
        <property type="protein sequence ID" value="EEZ41410"/>
        <property type="gene ID" value="VDA_002442"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0329">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1438588at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008747">
        <property type="term" value="F:N-acetylneuraminate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002220">
        <property type="entry name" value="DapA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020624">
        <property type="entry name" value="Schiff_base-form_aldolases_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128">
        <property type="entry name" value="PTHR12128"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00701">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001365">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00146">
        <property type="entry name" value="DHPICSNTHASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01130">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00665">
        <property type="entry name" value="DHDPS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR001365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="300" mass="31984" checksum="32521662AC796AAC" modified="2010-01-19" version="1">MEKLTGLIAAPHTPFDTNGNVNFAAIDQIAAHLIKDGVKGVYVCGTTGEGIHCSVEERKAIAERWVSASQGQLKITLHTGALSIVDTLELTRHAETLDIFATSAIGPCFFKPGSVDDLVEYCATVAAAAPSKGFYYYHSGMSGVNLDMEQFLIKADKKIPNLSGIKFNSGDLYEYQRCLRACDGKYDIPFGVDEHLPGALAVGAIGAVGSTYNYAAPHFTKMIEDFNNGDHAAVVKGMDNVIALIRVLVEFGGVAAGKAAMALHGIDCGDPRLPLRALTTEQKETVVAKMRDAGFLNAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ46</accession>
    <name>D0YZ46_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">7-cyano-7-deazaguanine synthase</fullName>
            <ecNumber evidence="2">6.3.4.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">7-cyano-7-carbaguanine synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">PreQ(0) synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Queuosine biosynthesis protein QueC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">queC</name>
        <name evidence="3" type="ORF">VDA_002559</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>7-carboxy-7-deazaguanine + ATP + NH4(+) = 7-cyano-7-deazaguanine + ADP + H(+) + H2O + phosphate</text>
            <dbReference type="Rhea" id="RHEA:27982"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:45075"/>
            <dbReference type="ChEBI" id="CHEBI:61036"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="2">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; 7-cyano-7-deazaguanine biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the QueC family.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.20" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300325.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002559"/>
    <dbReference type="EnsemblBacteria" id="EEZ41527">
        <property type="protein sequence ID" value="EEZ41527"/>
        <property type="gene ID" value="VDA_002559"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0603">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1681374at2"/>
    <dbReference type="UniPathway" id="UPA00391"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016879">
        <property type="term" value="F:ligase activity, forming carbon-nitrogen bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:queuosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01995">
        <property type="entry name" value="ExsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01633">
        <property type="entry name" value="QueC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018317">
        <property type="entry name" value="QueC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42914">
        <property type="entry name" value="PTHR42914"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06508">
        <property type="entry name" value="QueC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006293">
        <property type="entry name" value="ExsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00364">
        <property type="entry name" value="TIGR00364"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1 2" id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="234" mass="25886" checksum="46125D5C340CE7C2" modified="2010-01-19" version="1">MRKAVVVFSGGQDSTTCLIQALAHYDEVHCITFDYGQRHKLEIEVAQAITQELGVAAHKVMDVGLLNELAISSLTRDNIAVSHELQENGLPNSFVPGRNILFLTLAGIYAYQIGAEAVITGVCETDFSGYPDCRDEFVKSLNQSLVLGMDRPLRIETPLMWLNKAETWALADQYGKLDYVREKTLTCYNGIIGDGCGDCPSCDLRRAGLEDYLQHQESVMASLQDKQAHGQAER</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ64</accession>
    <name>D0YZ64_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 12">Heme exporter protein B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">VDA_002577</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 12">Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell inner membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 12">Belongs to the CcmB/CycW/HelB family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300379.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002577"/>
    <dbReference type="EnsemblBacteria" id="EEZ41545">
        <property type="protein sequence ID" value="EEZ41545"/>
        <property type="gene ID" value="VDA_002577"/>
    </dbReference>
    <dbReference type="GeneID" id="57341181"/>
    <dbReference type="eggNOG" id="COG2386">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1886257at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015232">
        <property type="term" value="F:heme transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003544">
        <property type="entry name" value="Cyt_c_biogenesis_CcmB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026031">
        <property type="entry name" value="Cyt_c_CcmB_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30070">
        <property type="entry name" value="PTHR30070"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03379">
        <property type="entry name" value="CcmB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002764">
        <property type="entry name" value="CcmB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01190">
        <property type="entry name" value="ccmB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="7 12" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="12" id="KW-0201">Cytochrome c-type biogenesis</keyword>
    <keyword evidence="11 12 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="93"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="127"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="194"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR002764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEZ41545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="222" mass="23817" checksum="27EF28EADB186945" modified="2010-01-19" version="1">MLTSITQVIRRELLIAFRRQADVFNPLWFFIIVITLFPLAVGPEPKLLARIAPGIVWVAALLAALLSMERLFRDDFADGSLEQMMLMPTPLPVLAFAKVIAHWLLTGLPLIIISPLLAILLSFDWSTWLAVVLTLLLGTPTLSFVGAIGVALTVGLRKGGVLLSLLILPLYIPVLIFATSAIDAASLGMAYNGQLALMGAMLVGSATMAPFAIAASLRISVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ75</accession>
    <name>D0YZ75_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Flagellar synthesis regulator FleN</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002588</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300407.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002588"/>
    <dbReference type="EnsemblBacteria" id="EEZ41556">
        <property type="protein sequence ID" value="EEZ41556"/>
        <property type="gene ID" value="VDA_002588"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0455">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1370117at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02038">
        <property type="entry name" value="FlhG-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033875">
        <property type="entry name" value="FlhG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025501">
        <property type="entry name" value="MinD_FleN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033756">
        <property type="entry name" value="YlxH/NBP35"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10609">
        <property type="entry name" value="ParA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003092">
        <property type="entry name" value="MinD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0966">Cell projection</keyword>
    <keyword evidence="3" id="KW-0969">Cilium</keyword>
    <keyword evidence="3" id="KW-0282">Flagellum</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="295" mass="32122" checksum="9024079F540920B9" modified="2010-01-19" version="1">MIENAMYDQASGLRRLTQIPSTKVIAVTGGKGGVGKTNITLNMAISMAKQGKRVMVFDADLGLANIDVMLGIRIGRNLSHVMASLCDLQDIIVEGPYGIKIIPASSGTRNMAELDPMQHSGLIRAFSSLQDEVDVLLIDTAAGISDMVLSFARASQDVLVVVCDEPTSITDAYALIKVLNRDYGVQRFKIVANMVRSYREGRDLYTKLTRVTERFLDANLELVACIPLDDAVRQAVRCQKLVVEAYPRSPASLALNSLATKATTWPSASNPGGHLEFFVERLLVKRSLEGECACE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZF2</accession>
    <name>D0YZF2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative ampG protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_002665</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300647.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002665"/>
    <dbReference type="EnsemblBacteria" id="EEZ41633">
        <property type="protein sequence ID" value="EEZ41633"/>
        <property type="gene ID" value="VDA_002665"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2211">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1165704at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004752">
        <property type="entry name" value="AmpG_permease/AT-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12778">
        <property type="entry name" value="PTHR12778"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="118"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="163"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="194"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="269"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="310"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="335"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="362"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="398"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="425"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="252"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="461" mass="50636" checksum="F8504FA970801F2E" modified="2010-01-19" version="1">MDQISQINKDQGWRVYLNPKALIMLALGFSSGLPILLVFGTLSFWLREADVSRTSIGFFSWVALAYGFKWIWSPLIDRFPVPLFCHLLGRRRGWMLFSQLLIVLSLCGMALSNPQTDLAQLAIFAVIVAFASASQDIVIDAYRIELATERLQAALAATYMTGYRLAMIMAGAGALAFAAWFGSDSGYNAHGWQIAYFIMAGFMLVGIITTLCIHEPTLDTQAIAKIEDEYFISLKQRGYSHKTAKLGAWFYTAAVMPFKDFFSRYGTSAITILLLISCYRISDVVMGVMSNAFYVDMGFTKTEVASVSKVFGVIMTLVGAGLGGILVSKFGTLRILALGALLSAITNLLFMVFTYMGNNLEMLTLVISADNLGAGIATAAFVTFMSSLTNVAFSATQYALFSSIMMLFPKFIAGFSGIYVDHFGYNIFFLTTALIGIPVLVLIKVLSNKNYHQPKTHSAQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZH6</accession>
    <name>D0YZH6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 8">S-(hydroxymethyl)glutathione dehydrogenase</fullName>
            <ecNumber evidence="5 8">1.1.1.284</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_002689</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>NAD(+) + S-(hydroxymethyl)glutathione = H(+) + NADH + S-formylglutathione</text>
            <dbReference type="Rhea" id="RHEA:19985"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57688"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58758"/>
            <dbReference type="EC" id="1.1.1.284"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>NADP(+) + S-(hydroxymethyl)glutathione = H(+) + NADPH + S-formylglutathione</text>
            <dbReference type="Rhea" id="RHEA:19981"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57688"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58758"/>
            <dbReference type="EC" id="1.1.1.284"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4 8">Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.284" evidence="5 8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300708.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002689"/>
    <dbReference type="EnsemblBacteria" id="EEZ41657">
        <property type="protein sequence ID" value="EEZ41657"/>
        <property type="gene ID" value="VDA_002689"/>
    </dbReference>
    <dbReference type="GeneID" id="57341040"/>
    <dbReference type="eggNOG" id="COG1062">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1859760at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106322">
        <property type="term" value="F:S-(hydroxymethyl)glutathione dehydrogenase NAD activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106321">
        <property type="term" value="F:S-(hydroxymethyl)glutathione dehydrogenase NADP activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006069">
        <property type="term" value="P:ethanol oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08300">
        <property type="entry name" value="alcohol_DH_class_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014183">
        <property type="entry name" value="ADH_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02818">
        <property type="entry name" value="adh_III_F_hyde"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="7 8 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="PKS_ER" evidence="9">
        <location>
            <begin position="15"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00021865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ41657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="376" mass="40244" checksum="22B8A4DD13B9D891" modified="2010-01-19" version="1">MTDKFIKSKAAVAWGPNQPLSIEEVDVMLPRKGEVLVRIIATGVCHTDAFTLSGDDPEGIFPSILGHEGGGIVEMVGEGVTSVAVGDHVIPLYTAECGECKFCKSGKTNLCQAVRETQGKGLMPDGTTRFYKDGQPIYHYMGCSTFSEYTVLPEISLAKVNKEAPLEEVCLLGCGVTTGMGAVLNTAKVEEGSTVAIFGLGGIGLSAIIGARMAGASRIIGVDLNETKFELATQLGATDCINPANYDKPIQEVIVEMTDGGVDYSFECIGNVNVMRSALECCHKGWGESIIIGVAGAGQEISTRPFQLVTGRVWRGSAFGGVKGRSELPEIVERYMAGEFGLQEFITHTMALEDINEAFELMHKGESIRTVIHYNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZM1</accession>
    <name>D0YZM1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Exopolyphosphatase</fullName>
            <ecNumber evidence="3">3.6.1.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_002734</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[phosphate](n) + H2O = [phosphate](n-1) + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21528"/>
            <dbReference type="Rhea" id="RHEA-COMP:9859"/>
            <dbReference type="Rhea" id="RHEA-COMP:14279"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16838"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="EC" id="3.6.1.11"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GppA/Ppx family.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.11" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300855.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002734"/>
    <dbReference type="EnsemblBacteria" id="EEZ41702">
        <property type="protein sequence ID" value="EEZ41702"/>
        <property type="gene ID" value="VDA_002734"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0248">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1862004at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004309">
        <property type="term" value="F:exopolyphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006793">
        <property type="term" value="P:phosphorus metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022371">
        <property type="entry name" value="Exopolyphosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003695">
        <property type="entry name" value="Ppx_GppA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030673">
        <property type="entry name" value="PyroPPase_GppA_Ppx"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02541">
        <property type="entry name" value="Ppx-GppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001267">
        <property type="entry name" value="Pyrophosphatase_GppA_Ppx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03706">
        <property type="entry name" value="exo_poly_only"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ppx-GppA" evidence="5">
        <location>
            <begin position="24"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="504" mass="57171" checksum="F8EEDAADFD002B88" modified="2010-01-19" version="1">MNSEYKAPREIAAIDLGSNSFHMVVARIIGNSLQIISRHKQRVRLASGLDSHNNLNQTVMQQGLQCLAMFAERLQDFPQADVRIAATYTLRQAKNAHIFLKRAEHYLPYPIEIIPGTEEARLIYLGVAHTHESMAQKLVIDIGGGSTELIIGAGFTPQLLYSKHMGCVSYSQRFFADGKLNKRNFHQAQLAAKQKLESIAEQYKALGWQFALGSSGTIKAIREVLDAQNPALDEGDITLAKLNQLIEQMIKCKKITQLDLPGLSADRQPVFAAGVAILSAIFQELNIATLSFSSGALREGLLYEMESRFRQQDIRTRTAKALAKQYHVDVHQATRVKETALYLYRQLTPSEDNNSELTSLLNWAALLHEVGLSISYPGFHRHSSYLLRYSTMPGFNLEQQTLLATLARFQRKSLKLTEMAELSLYSRKQIYPMIRALRLAVIFNGQRRGLPHPTIHLKANQQHWHLTLPSEWLKENQLLEADLIREQAYWHKVNWQLSYAQDLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZR4</accession>
    <name>D0YZR4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UPF0125 protein VDA_002777</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002777</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the UPF0125 (RnfH) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002777"/>
    <dbReference type="EnsemblBacteria" id="EEZ41745">
        <property type="protein sequence ID" value="EEZ41745"/>
        <property type="gene ID" value="VDA_002777"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2914">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00460">
        <property type="entry name" value="UPF0125_RnfH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016155">
        <property type="entry name" value="Mopterin_synth/thiamin_S_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005346">
        <property type="entry name" value="RnfH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037021">
        <property type="entry name" value="RnfH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37483">
        <property type="entry name" value="PTHR37483"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03658">
        <property type="entry name" value="Ub-RnfH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54285">
        <property type="entry name" value="SSF54285"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="87" mass="10082" checksum="632EA04D7B3C0A74" modified="2010-01-19" version="1">MVYALPQEQKVLKLAVQPNTPVQEIIEQSGILTQYPDIDLKKNKVGVYSRNVRLDSTVYDGDRIEIYRPITADPREIRRKRLEQAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZX8</accession>
    <name>D0YZX8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7 8">Transcription elongation factor GreA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Transcript cleavage factor GreA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">greA</name>
        <name evidence="11" type="ORF">VDA_002841</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7 8">Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the GreA/GreB family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301167.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002841"/>
    <dbReference type="EnsemblBacteria" id="EEZ41809">
        <property type="protein sequence ID" value="EEZ41809"/>
        <property type="gene ID" value="VDA_002841"/>
    </dbReference>
    <dbReference type="GeneID" id="57340874"/>
    <dbReference type="eggNOG" id="COG0782">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1536415at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070063">
        <property type="term" value="F:RNA polymerase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032784">
        <property type="term" value="P:regulation of DNA-templated transcription, elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00105">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036953">
        <property type="entry name" value="GreA/GreB_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018151">
        <property type="entry name" value="TF_GreA/GreB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006359">
        <property type="entry name" value="Tscrpt_elong_fac_GreA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028624">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001437">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023459">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022691">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036805">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30437">
        <property type="entry name" value="PTHR30437"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01272">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03449">
        <property type="entry name" value="GreA_GreB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006092">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46557">
        <property type="entry name" value="SSF46557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01462">
        <property type="entry name" value="greA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00829">
        <property type="entry name" value="GREAB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00830">
        <property type="entry name" value="GREAB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="11" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 7 8" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="GreA_GreB_N" evidence="10">
        <location>
            <begin position="4"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="domain" description="GreA_GreB" evidence="9">
        <location>
            <begin position="82"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ41809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="157" mass="17596" checksum="4FD2BE3044EAC817" modified="2010-01-19" version="1">MDKVPMTVRGEQKLRQELEVLMKRRPLISQAIAEARELGDLKENAEYHAAREEQGICEAQIRDIEYKLSVAQVIDVTKMPNSGKVIFGTTVTLLNLDTDEETTYRIVGDDEADFKQNLISVNSPIARGLIGKMEGDEVQIATPGGTKEFEIVEVQYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z029</accession>
    <name>D0Z029_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase</fullName>
            <shortName evidence="5">MTA/SAH nucleosidase</shortName>
            <shortName evidence="5">MTAN</shortName>
            <ecNumber evidence="5">3.2.2.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">5'-deoxyadenosine nucleosidase</fullName>
            <shortName evidence="5">DOA nucleosidase</shortName>
            <shortName evidence="5">dAdo nucleosidase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">5'-methylthioadenosine nucleosidase</fullName>
            <shortName evidence="5">MTA nucleosidase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">S-adenosylhomocysteine nucleosidase</fullName>
            <shortName evidence="5">AdoHcy nucleosidase</shortName>
            <shortName evidence="5">SAH nucleosidase</shortName>
            <shortName evidence="5">SRH nucleosidase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">mtnN</name>
        <name evidence="7" type="ORF">VDA_002892</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>5'-deoxyadenosine + H2O = 5-deoxy-D-ribose + adenine</text>
            <dbReference type="Rhea" id="RHEA:29859"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:149540"/>
            <dbReference type="EC" id="3.2.2.9"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>H2O + S-adenosyl-L-homocysteine = adenine + S-(5-deoxy-D-ribos-5-yl)-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:17805"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:58195"/>
            <dbReference type="EC" id="3.2.2.9"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>H2O + S-methyl-5'-thioadenosine = 5-(methylsulfanyl)-D-ribose + adenine</text>
            <dbReference type="Rhea" id="RHEA:13617"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:78440"/>
            <dbReference type="EC" id="3.2.2.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 5">Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; S-methyl-5-thio-alpha-D-ribose 1-phosphate from S-methyl-5'-thioadenosine (hydrolase route): step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.9" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301283.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002892"/>
    <dbReference type="EnsemblBacteria" id="EEZ41860">
        <property type="protein sequence ID" value="EEZ41860"/>
        <property type="gene ID" value="VDA_002892"/>
    </dbReference>
    <dbReference type="GeneID" id="57340816"/>
    <dbReference type="eggNOG" id="COG0775">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1860206at2"/>
    <dbReference type="UniPathway" id="UPA00904">
        <property type="reaction ID" value="UER00871"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008782">
        <property type="term" value="F:adenosylhomocysteine nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008930">
        <property type="term" value="F:methylthioadenosine nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019509">
        <property type="term" value="P:L-methionine salvage from methylthioadenosine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019284">
        <property type="term" value="P:L-methionine salvage from S-adenosylmethionine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009164">
        <property type="term" value="P:nucleoside catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01684">
        <property type="entry name" value="Salvage_MtnN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010049">
        <property type="entry name" value="MTA_SAH_Nsdase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000845">
        <property type="entry name" value="Nucleoside_phosphorylase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01048">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="SSF53167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01704">
        <property type="entry name" value="MTA/SAH-Nsdase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 5" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNP_UDP_1" evidence="6">
        <location>
            <begin position="2"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="174"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="12"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="198"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="232" mass="24764" checksum="0A4E1C527254EDE3" modified="2010-01-19" version="1">MKIGIIGAMEQEVAILKDQLTDCQTHNKAGCTIYTGRLNGAEIALLQSGIGKVAAAVGTTILLEVFQPDVVINTGSAGGFDSSLNVGDVVISTEVRYHDADVTAFGYEMGQMAQQPAAFISDSNLMEVAEQALATMTDTHAVRGLICTGDAFVCTEEKQNFIRTHFPTVVAVEMEAAAIAQVCHQFKLPFVVVRAISDVADKESPMSFDEFLPLAAQSSSVMVAKMVELLNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z045</accession>
    <name>D0Z045_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">(GlcNAc)2 ABC transporter ATP-binding component 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_002908</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301319.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002908"/>
    <dbReference type="EnsemblBacteria" id="EEZ41876">
        <property type="protein sequence ID" value="EEZ41876"/>
        <property type="gene ID" value="VDA_002908"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0444">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1101128at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01727">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="8"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="42"/>
            <end position="49"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="323" mass="36055" checksum="9B2C1A06DE5C2FA4" modified="2010-01-19" version="1">MSNPQISIRNLCVDYITDAGDVRAVNNVSFDIGKGEIFGLAGESGCGKSTVAFSLMRLHKPPAFITGGEVIFDGHGDILKYSDMQMAAFRWSEISMVFQSAMNALNPVLTMEEQFCDVIMRHTNMTRQQAIRRAEGLLEIVDIHPNRLRDFPHQFSGGMRQRLVIAIALALNPKMIIMDEPTTALDVVVQREILQKIYALKEEFGFSILFITHDLSLMVEFSDRIGIMYSGELIEVAPSKQILENPYHPYTEGLGSSFPPLTGPKTHLTGIPGNPLNLLEIPQGCRFQARCSKAVDACFKQPTQLCQIEPGRFSNCHLFTKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0S4</accession>
    <name>D0Z0S4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_003138</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003138"/>
    <dbReference type="EnsemblBacteria" id="EEZ42105">
        <property type="protein sequence ID" value="EEZ42105"/>
        <property type="gene ID" value="VDA_003138"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031Q0U">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ42105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="42" mass="4169" checksum="720A8F02E5B3600D" modified="2010-01-19" version="1">MLDTILSFSVAMPAVSELAANGSGQFAAGILALIAAVNFTGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-08-12" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0Y3</accession>
    <name>D0Z0Y3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Threonylcarbamoyl-AMP synthase</fullName>
            <shortName evidence="7">TC-AMP synthase</shortName>
            <ecNumber evidence="7">2.7.7.87</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">L-threonylcarbamoyladenylate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">tRNA threonylcarbamoyladenosine biosynthesis protein TsaC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">tsaC</name>
        <name evidence="10" type="ORF">VDA_003197</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + hydrogencarbonate + L-threonine = diphosphate + H2O + L-threonylcarbamoyladenylate</text>
            <dbReference type="Rhea" id="RHEA:36407"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="ChEBI" id="CHEBI:73682"/>
            <dbReference type="EC" id="2.7.7.87"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the SUA5 family. TsaC subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.87" evidence="7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302134.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003197"/>
    <dbReference type="EnsemblBacteria" id="EEZ42164">
        <property type="protein sequence ID" value="EEZ42164"/>
        <property type="gene ID" value="VDA_003197"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0009">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1913202at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061710">
        <property type="term" value="F:L-threonylcarbamoyladenylate synthase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002949">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01852">
        <property type="entry name" value="TsaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017945">
        <property type="entry name" value="DHBP_synth_RibB-like_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023535">
        <property type="entry name" value="TC-AMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006070">
        <property type="entry name" value="YrdC-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17490:SF8">
        <property type="entry name" value="PTHR17490:SF8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01300">
        <property type="entry name" value="Sua5_yciO_yrdC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55821">
        <property type="entry name" value="SSF55821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00057">
        <property type="entry name" value="TIGR00057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51163">
        <property type="entry name" value="YRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 7" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="YrdC-like" evidence="9">
        <location>
            <begin position="1"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ42164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="185" mass="20247" checksum="E82A8AA3995DE503" modified="2010-01-19" version="1">MDNFAQVVAALQQGEVIGYPTEAVFGVGCDPDSEQAVHKLLALKQRPIEKGLILIAADYDQLLAYVDESQLTTNQLEQIKNSWPGPVTWVMPTKPSVPKFLTGQFETIAVRVSDHPLVQQLCRQFGKPITSTSANLTGQEPGRTYQDVEAQLGHYLAAILQGEVGGRDNPSEIRDAQTGKVFRQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0Y4</accession>
    <name>D0Z0Y4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">N5-carboxyaminoimidazole ribonucleotide mutase</fullName>
            <shortName evidence="3 4">N5-CAIR mutase</shortName>
            <ecNumber evidence="3 4">5.4.99.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">5-(carboxyamino)imidazole ribonucleotide mutase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">purE</name>
        <name evidence="7" type="ORF">VDA_003198</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 4">Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 4">
            <text>5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + H(+) = 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate</text>
            <dbReference type="Rhea" id="RHEA:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58730"/>
            <dbReference type="ChEBI" id="CHEBI:77657"/>
            <dbReference type="EC" id="5.4.99.18"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 4">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5-phospho-D-ribosyl)imidazole (N5-CAIR route): step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the AIR carboxylase family. Class I subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.18" evidence="3 4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302138.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003198"/>
    <dbReference type="EnsemblBacteria" id="EEZ42165">
        <property type="protein sequence ID" value="EEZ42165"/>
        <property type="gene ID" value="VDA_003198"/>
    </dbReference>
    <dbReference type="GeneID" id="57340394"/>
    <dbReference type="eggNOG" id="COG0041">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1701464at2"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00943"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034023">
        <property type="term" value="F:5-(carboxyamino)imidazole ribonucleotide mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01929">
        <property type="entry name" value="PurE_classI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033747">
        <property type="entry name" value="PurE_ClassI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000031">
        <property type="entry name" value="PurE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024694">
        <property type="entry name" value="PurE_prokaryotes"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00731">
        <property type="entry name" value="AIRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001338">
        <property type="entry name" value="AIR_carboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01001">
        <property type="entry name" value="AIRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01162">
        <property type="entry name" value="purE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="1 3 4" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AIRC" evidence="6">
        <location>
            <begin position="1"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="12"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR001338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001338-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ42165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="161" mass="16897" checksum="CA5A404F19515035" modified="2010-01-19" version="1">MKVGIIMGSQSDWPTMQHAAEMLERFNVEYETKVVSAHRTPHLLAEYAQNAQQRGITVIIAGAGGAAHLPGMTAAYTSLPVLGVPVQSRALKGLDSLLSIVQMPKGIAVGTLAIGEAGAANAGLLAAQIIATSNEEVRLAIEAFRQQQTDTVLSQPDPGLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0Y7</accession>
    <name>D0Z0Y7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Rossmann fold nucleotide-binding protein Smf possibly involved in DNA uptake</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_003201</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DprA/Smf family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302146.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003201"/>
    <dbReference type="EnsemblBacteria" id="EEZ42168">
        <property type="protein sequence ID" value="EEZ42168"/>
        <property type="gene ID" value="VDA_003201"/>
    </dbReference>
    <dbReference type="GeneID" id="57340390"/>
    <dbReference type="eggNOG" id="COG0758">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1881437at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009294">
        <property type="term" value="P:DNA-mediated transformation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003488">
        <property type="entry name" value="DprA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041614">
        <property type="entry name" value="DprA_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43022">
        <property type="entry name" value="PTHR43022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02481">
        <property type="entry name" value="DNA_processg_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17782">
        <property type="entry name" value="DprA_WH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00732">
        <property type="entry name" value="dprA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DprA_WH" evidence="2">
        <location>
            <begin position="312"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ42168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="364" mass="39164" checksum="8C39EEDDA4995E50" modified="2010-01-19" version="1">MDNIHAWLKLVAVPGLGGHRISRLLQHAMPEQIMAMDESELRSIGLTLKQVAAIKHPDNKKIDLALNWQQRPHCHIIPLVSPLYPPLLKEISSAPPLLFVKGDPSFLAQPQIAIIGSRSASIDGREIAADFAANIVAQNYVVTSGLALGIDSQAHQGALRHGGATIAVLGSGLEQIYPACHKSLAASIVEQGALVSEFWPQEKPRAQFFPRRNRIISGLSVGVLVVEAAQKSGSLITANYALEQGREVFAIPGSIYNPASRGCNALIKSGAKLVESAQDIFEEVGALTECAINHQLSQALPETENEQLPFPELLATVGSEVIPVDVLAERSQMPVHDVMTQLLELELLGLVTALPGGYIRTRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z110</accession>
    <name>D0Z110_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">L-threonine dehydratase</fullName>
            <ecNumber evidence="11">4.3.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Threonine deaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ilvA</name>
        <name evidence="13" type="ORF">VDA_003224</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10 11">Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>L-threonine = 2-oxobutanoate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:22108"/>
            <dbReference type="ChEBI" id="CHEBI:16763"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="EC" id="4.3.1.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 11">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 11">Amino-acid biosynthesis; L-isoleucine biosynthesis; 2-oxobutanoate from L-threonine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the serine/threonine dehydratase family.</text>
    </comment>
    <dbReference type="EC" id="4.3.1.19" evidence="11"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302209.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003224"/>
    <dbReference type="EnsemblBacteria" id="EEZ42191">
        <property type="protein sequence ID" value="EEZ42191"/>
        <property type="gene ID" value="VDA_003224"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1171">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1876944at2"/>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00054"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004794">
        <property type="term" value="F:L-threonine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1020.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000634">
        <property type="entry name" value="Ser/Thr_deHydtase_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001721">
        <property type="entry name" value="TD_ACT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038110">
        <property type="entry name" value="TD_ACT-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005787">
        <property type="entry name" value="Thr_deHydtase_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00585">
        <property type="entry name" value="Thr_dehydrat_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01124">
        <property type="entry name" value="ilvA_2Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51672">
        <property type="entry name" value="ACT_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00165">
        <property type="entry name" value="DEHYDRATASE_SER_THR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9 11" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="5 11" id="KW-0412">Isoleucine biosynthesis</keyword>
    <keyword evidence="8 11 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 11" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ACT-like" evidence="12">
        <location>
            <begin position="342"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="domain" description="ACT-like" evidence="12">
        <location>
            <begin position="437"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ42191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="519" mass="57014" checksum="7B133E865F7B29B1" modified="2010-01-19" version="1">MSQADVIEATPSPLQGSDYLRQILKAPVYEVAQVTPLQTMERLSTRLGNHIGLKREDRQPVHSFKLRGAYNMMAQLSHEQKQAGVIAASAGNHAQGLALSAQKLGVPAIIVMPLTTPDIKVSAVRGFGGDVILHGSNFDEAKTHAQQLSQQHGYTFIPPFDHPQIIAGQGTIGLELIQQNGHLDYIFVPVGGGGLAAGVAVLVKQLMPEIKVIGVEAEDSACLNAALDAGEPVTLDQVGMFADGVAVKRIGDETFRLCQQFLDGVITVSSDEICAAVKDIFEDTRAIAEPSGALSLAGLKKYAEQYQLTQQQLAAVLSGANLNFHGLRYVSERCELGEKREGLLAVTIPERPGAFLDFCRLLGGRAVTEFNYRYNHNQLANIFVGVRLLQGQEELDAIITELRKGGYPVVDLSDDEMAKVHIRYMIGGKPANALKERLYSFEFPEYPGALIKFLNTLGTHWNISLFNYRNHGADYGRVLCGFELDDKDLLSFTSYLRELGYHWKDETDNPAYRFFLAQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z125</accession>
    <name>D0Z125_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribosomal RNA small subunit methyltransferase G</fullName>
            <ecNumber evidence="2">2.1.1.170</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">16S rRNA 7-methylguanosine methyltransferase</fullName>
            <shortName evidence="2">16S rRNA m7G methyltransferase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rsmG</name>
        <name evidence="3" type="ORF">VDA_003239</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>guanosine(527) in 16S rRNA + S-adenosyl-L-methionine = N(7)-methylguanosine(527) in 16S rRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42732"/>
            <dbReference type="Rhea" id="RHEA-COMP:10209"/>
            <dbReference type="Rhea" id="RHEA-COMP:10210"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74480"/>
            <dbReference type="EC" id="2.1.1.170"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.170" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302257.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003239"/>
    <dbReference type="EnsemblBacteria" id="EEZ42206">
        <property type="protein sequence ID" value="EEZ42206"/>
        <property type="gene ID" value="VDA_003239"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0357">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1590629at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070043">
        <property type="term" value="F:rRNA (guanine-N7-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00074">
        <property type="entry name" value="16SrRNA_methyltr_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003682">
        <property type="entry name" value="rRNA_ssu_MeTfrase_G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31760">
        <property type="entry name" value="PTHR31760"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02527">
        <property type="entry name" value="GidB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003078">
        <property type="entry name" value="GidB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00138">
        <property type="entry name" value="rsmG_gidB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="2">
        <location>
            <begin position="124"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ42206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="206" mass="23325" checksum="F6886707B54B8803" modified="2010-01-19" version="1">MKQRLAQLISQTDLQVTEQQLDQLVGYVELLNKWNKAYNLTSVRDPNEMLVKHIMDSIVVSEYLKGDHYIDVGTGPGLPGIPLAIMCPEKSFTLLDSLGKRIRFIRQVIFELKITNVTPVQSRVEEFQPEEGFDGVLSRAFASMTDMVTWCHHLPKANGNFLALKGQFSEQEVAELPDWCTVNEVNSLRVPELDGERHLVVLSAKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z179</accession>
    <name>D0Z179_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lysophospholipase L2</fullName>
            <ecNumber evidence="3">3.1.1.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_003293</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.1.5" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003293"/>
    <dbReference type="ESTHER" id="lisda-d0z179">
        <property type="family name" value="Monoglyceridelipase_lysophospholip"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ42260">
        <property type="protein sequence ID" value="EEZ42260"/>
        <property type="gene ID" value="VDA_003293"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1694750at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004622">
        <property type="term" value="F:lysophospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102545">
        <property type="term" value="F:phosphatidyl phospholipase B activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydrolase_4" evidence="2">
        <location>
            <begin position="52"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ42260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="330" mass="37852" checksum="79BC59D2C16784BB" modified="2010-01-19" version="1">MTDTSSYPLSQEAQFSQTMQGPVAELWQHRQEGIFHGVDGLRIGWMAMTHTKNDKVIVVVNGRIESYWKYQETIYDLFQQGYDVFSLDHRGQGVSDRLTTIHDLGHIAEFDDYVTDLKTLFDQIITPRGYQQHFMLGHSMGGTISSLFLSRFPNIIDRAAMTAPMHGIYLDNPVMKKISYPLLRLIDSLQTQPQYTFTQKGYVAKPFIDNPYTHSEVRYQWFRDLYQHKPELQIGGPSSRWVWQGMRASQHCIEQATNIQAPLLIIQAGNDRIVDNDKQQQFLAAMQSGKGQLITIDGANHELLFESDIYRNQSLNAILSHFANQSTVSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1H8</accession>
    <name>D0Z1H8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Met repressor</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9 10">Met regulon regulatory protein MetJ</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">metJ</name>
        <name evidence="11" type="ORF">VDA_003392</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">This regulatory protein, when combined with SAM (S-adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 10">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="10">Does not bind DNA by a helix-turn-helix motif.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the MetJ family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302629.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003392"/>
    <dbReference type="EnsemblBacteria" id="EEZ42359">
        <property type="protein sequence ID" value="EEZ42359"/>
        <property type="gene ID" value="VDA_003392"/>
    </dbReference>
    <dbReference type="GeneID" id="57340158"/>
    <dbReference type="eggNOG" id="COG3060">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1738030at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.140.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00744">
        <property type="entry name" value="MetJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002084">
        <property type="entry name" value="Met_repressor_MetJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023453">
        <property type="entry name" value="Met_repressor_MetJ_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01340">
        <property type="entry name" value="MetJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8 10" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0678">Repressor</keyword>
    <keyword evidence="10" id="KW-0804">Transcription</keyword>
    <keyword evidence="10" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ42359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="105" mass="12073" checksum="53D44147CE60D91B" modified="2010-01-19" version="1">MAEWNGEYISPYAEHGKKNEQVKKITVSIPLKVLKILTDERTRRQVNNLRHATNSELLCEAFLHAYTGQPLPTDDDIRKDRPDDIPSEAKAMMDEMGISYENPDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1I2</accession>
    <name>D0Z1I2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">N-acetyl-gamma-glutamyl-phosphate reductase</fullName>
            <shortName evidence="4">AGPR</shortName>
            <ecNumber evidence="4">1.2.1.38</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">N-acetyl-glutamate semialdehyde dehydrogenase</fullName>
            <shortName evidence="4">NAGSA dehydrogenase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">argC</name>
        <name evidence="7" type="ORF">VDA_003396</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>N-acetyl-L-glutamate 5-semialdehyde + NADP(+) + phosphate = H(+) + N-acetyl-L-glutamyl 5-phosphate + NADPH</text>
            <dbReference type="Rhea" id="RHEA:21588"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29123"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57936"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.2.1.38"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 3/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.38" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302638.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003396"/>
    <dbReference type="EnsemblBacteria" id="EEZ42363">
        <property type="protein sequence ID" value="EEZ42363"/>
        <property type="gene ID" value="VDA_003396"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0002">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="951261at2"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00108"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003942">
        <property type="term" value="F:N-acetyl-gamma-glutamyl-phosphate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00150">
        <property type="entry name" value="ArgC_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023013">
        <property type="entry name" value="AGPR_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000706">
        <property type="entry name" value="AGPR_type-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000534">
        <property type="entry name" value="Semialdehyde_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012280">
        <property type="entry name" value="Semialdhyde_DH_dimer_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01118">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02774">
        <property type="entry name" value="Semialdhyde_dhC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00859">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01850">
        <property type="entry name" value="argC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01224">
        <property type="entry name" value="ARGC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0521">NADP</keyword>
    <keyword evidence="3 4 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Semialdhyde_dh" evidence="6">
        <location>
            <begin position="3"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="active site" evidence="4 5">
        <location>
            <position position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ42363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="337" mass="36257" checksum="4A33BBCD0C896B51" modified="2010-01-19" version="1">MLKTIVIGASGYTGAELATLVQRHPHLALTGLYVSSQSLDAHKSIAQLHRQLSGVVEMPLLPLDDPQAVAGSADVVLLATAHEVSHQLAPIFLAAGCQVFDLSGAYRVNQASFYQDFYGFTHQFPNLLDEAVYGLAEWNYQAIAKGQLIAVPGCYPTASQLALKPICNAHLLDPQVPPVINAISGVSGAGRKASLNNSFCEVSLQAYGVFNHRHQPEISTHLDCPVIFTPHLGSFKRGILATITAKLKPGVTLADITQAMEQAYLTNDKAHAVRLCYQNTANLQAVVNTGFCDLSWHVNDQHLILTSAIDNLLKGASSQAVQCINIRNNFPPMTAVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1I7</accession>
    <name>D0Z1I7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Peroxiredoxin family protein/glutaredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_003401</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302648.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003401"/>
    <dbReference type="EnsemblBacteria" id="EEZ42368">
        <property type="protein sequence ID" value="EEZ42368"/>
        <property type="gene ID" value="VDA_003401"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0678">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0695">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="892697at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097573">
        <property type="term" value="F:glutathione oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004362">
        <property type="term" value="F:glutathione-disulfide reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03013">
        <property type="entry name" value="PRX5_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011767">
        <property type="entry name" value="GLR_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011906">
        <property type="entry name" value="Glutaredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014025">
        <property type="entry name" value="Glutaredoxin_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037944">
        <property type="entry name" value="PRX5-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013740">
        <property type="entry name" value="Redoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10430">
        <property type="entry name" value="PTHR10430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08534">
        <property type="entry name" value="Redoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00160">
        <property type="entry name" value="GLUTAREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02190">
        <property type="entry name" value="GlrX-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00195">
        <property type="entry name" value="GLUTAREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="4" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="5">
        <location>
            <begin position="4"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ42368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="242" mass="26586" checksum="C0EADC8FE2D1E4D9" modified="2010-01-19" version="1">MFASKEGQAVPQVTFHTRQGDQWVDVTTNDLFANKTVIVFSLPGAFTPTCSSSHLPRYNELASVFAENGVDDILCVSVNDTFVMNAWKADQEAENIIFVPDGNGEFTQGMGMLVEKEDLGFGPRSWRYSMLVKNGVIEKMFIENEEPGDPFKVSDADTMLKYIAPEQKLQESIAVFTKPGCPFCAKAKQNLIDKGLQYEEIILGKDATTVSLRAISGRSTVPQVFIGGKHIGGSEELEAFLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1K2</accession>
    <name>D0Z1K2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hypothetical extracellular nuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_003416</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302670.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003416"/>
    <dbReference type="EnsemblBacteria" id="EEZ42383">
        <property type="protein sequence ID" value="EEZ42383"/>
        <property type="gene ID" value="VDA_003416"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2374">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1884225at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018815" evidence="1">
        <location>
            <begin position="23"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="domain" description="Endo/exonuclease/phosphatase" evidence="2">
        <location>
            <begin position="307"/>
            <end position="674"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ42383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="781" mass="86456" checksum="855AD5CC0A7996FA" modified="2010-01-19" version="1">MNKLCYSPIALALAVTPLPSLADSFTCQDQVLTPIYQLQGDGERSPLVPAGQYQSNESYFVQGVVTKKVTGLYQGFFIQDAQGDNNPQTSDGIFVYTGSKLNVDVKPGMQVCLLAPVKEHYQQTQLVAHPDQIELGAMTQPLAPTPVVIEADETLAQAMERYEGMWVKLTKQSQLTVTRNFGFDYSSYRNNMVLSHQAPLLKPTQIYIAGSEQAQALANANRSNQLYIDTDQKPANGVIPYFPDFDPEQGYIRVGDGLVNLEGVIGFSYNNYRLLPTNSVTSADFIHYQDRTVAPEIVTDSNLKVASFNVLNFFTSASSIGGDLNVTCQDQADADASKGCNRGAKTEADFVLQRTKIVNALTAMDADIVGIMEMENNGFGDNSAIANLVEHLNAQWSDTSQHYRFIEIAAKDKNQGQYFGSDAIMVAMLYRPAKVTPKGDAEVIRMPEQHIVGTSPEGEEKQLDKYQRDSLLQSFTVNHAKQKQKTLTIVVNHLKSKGSGCYEDWVNGEFDSDPADLQRRCNAFRVSAAQVLANSLKKVKGDLLVIGDMNSYGMEDPIRVLTNYKPNQAQRKIMTASGTSIAGVPYQAVGQEVGKGLGLKNLATQWHGKDSYSYSFGGELGSLDHALANKSLAKKVVGIEDWHINSVENALFEYSRKYSGELAKSEGPYSASDHDPVIISLHYKMKQPGFNLTIHNRSEQPIYPVFDRWYWDSTKPWLFGGDSRHYDEQDSFLKWMGISTGDKVRLSVLAYGVYEVPCGYSPLKLTGKLTAVYNGDHCRIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1P1</accession>
    <name>D0Z1P1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">50S ribosomal protein L18</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rplR</name>
        <name evidence="8" type="ORF">VDA_003455</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the universal ribosomal protein uL18 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302818.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003455"/>
    <dbReference type="EnsemblBacteria" id="EEZ42422">
        <property type="protein sequence ID" value="EEZ42422"/>
        <property type="gene ID" value="VDA_003455"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0256">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1963491at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01337_B">
        <property type="entry name" value="Ribosomal_L18_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005484">
        <property type="entry name" value="Ribosomal_L18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004389">
        <property type="entry name" value="Ribosomal_L18_bac-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12899">
        <property type="entry name" value="PTHR12899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00861">
        <property type="entry name" value="Ribosomal_L18p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00060">
        <property type="entry name" value="L18_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 7" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ42422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="117" mass="12612" checksum="2C2AF0E696484E4B" modified="2010-01-19" version="1">MDKKTSRIRRATRARRKIAELGATRLVVHRTPRHVYAQVIAANGSEVIAAASTLEKAIREQVKNTGNKDAATAVGKAIAERAIEKGVSSVAFDRSGFQYHGRVAALAEAAREAGLKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1U3</accession>
    <name>D0Z1U3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytoplasmic axial filament protein CafA and Ribonuclease G</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_003507</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303638.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003507"/>
    <dbReference type="EnsemblBacteria" id="EEZ42474">
        <property type="protein sequence ID" value="EEZ42474"/>
        <property type="gene ID" value="VDA_003507"/>
    </dbReference>
    <dbReference type="GeneID" id="57340020"/>
    <dbReference type="eggNOG" id="COG1530">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1209444at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019307">
        <property type="entry name" value="RNA-bd_AU-1/RNase_E/G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004659">
        <property type="entry name" value="RNase_E/G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30001">
        <property type="entry name" value="PTHR30001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10150">
        <property type="entry name" value="RNase_E_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00757">
        <property type="entry name" value="RNaseEG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="S1 motif" evidence="6">
        <location>
            <begin position="39"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ42474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="489" mass="55266" checksum="F578AFFCE4633CFD" modified="2010-01-19" version="1">MSTELLINVTPSETRVAMIEDGNLQEIHIERESKRGIVGNIYKGRVSRVLPGMQAAFVDIGLDKAAFLHASDIVPHTECVAENEKQQFQVRDISELVRQGQDLVVQVVKDPLGTKGARLTTDVTLPSRYLVFMPGASHVGVSQRIESEHERERLKKIVMPHCDDLGGFIIRTAAEGASDEELSQDAAFLKHLWRKVIERRAKYKTRSMLYGELGLAQRILRDFVGTEIHNIKVDSRLAFDKLKEFTDEFVPEVTENIEYYSGDQPIFDLYDTENEIQRSLDRKVELKSGGYLIIDQTEAMTTVDINTGAFVGRRNLEETIFNTNIEATKAIARQLRLRNLGGIIIIDFIDMAGEDHQRRVLQALEQALSGDRVKTNINGFTQLGLVEMTRKRTRESIEHVLCGTCPTCKGRGTVKTVESVCYEILREVTRVNRAYDADRFVVYVSPVVADALSGDEYHALAELEVFIGKEVKIKAEPLYIQEQFDVVMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z206</accession>
    <name>D0Z206_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001967</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299043.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001967"/>
    <dbReference type="EnsemblBacteria" id="EEZ40935">
        <property type="protein sequence ID" value="EEZ40935"/>
        <property type="gene ID" value="VDA_001967"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1134793at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="G" evidence="2">
        <location>
            <begin position="284"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="514" mass="57513" checksum="9E71EB65B2AE7765" modified="2010-01-19" version="1">MNKIKNSYHLLSRLSDGFVPLVMLAIAIPILVLAGFGIADLVTNGQWVLFFALIASSCLIIFVPYWWMRRSRTVETAIKQDLEGLDVEGNPAWTAKDQQIWQQANETIVRQINEEPEWDNLKAHALLVLTQVAASYNQKSGKALSFTAPEFLLMTEEVSRRYRRFLRENIPFVDKVSITTLQQGYDLSDKLGYAKSAYDIYRLFRITTPTGWLAEARGMVLGQLFDNVSAEIQFKLKATLLQEVASVAIDLYSGQFKLADDELPPSEIEAKDSKAHAAKVSPLRVAVVGQVSAGKSSLVNALIGEMAAEVSALPSTDQATVHQCTVDGIDLVHLIDLPGLDGDKATQKKIVSQITNSDLVLWVLKANQSARKLDVELRQAVDEFYQLAANQNRKAPKILVLVNQVDRLPPLDEWQPPYDLSNPQTQKGKVIAQAVEFNKEKLNPDIILPLCVSQDVPQFNVDTLQQAIVSAYEDGVNTQLNRRRVEGDRLDLTEEAKRLYHLGEVLFKAYRKQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z207</accession>
    <name>D0Z207_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sodium/glucose cotransporter (Na(+)/glucose symporter)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_001968</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40936">
        <property type="protein sequence ID" value="EEZ40936"/>
        <property type="gene ID" value="VDA_001968"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4146">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
        <property type="entry name" value="SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00813">
        <property type="entry name" value="sss"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="85"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="126"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="187"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="242"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="269"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="294"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="322"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="362"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ40936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="382" mass="41224" checksum="876F144172D37A0A" modified="2010-01-19" version="1">MMYAIIGLALFAIIYSLYGGLSAVVWTDVIQVFFLVLGGLLTTFMALSYIGGADGVLGGLSHMIDAAPEHFEMILDQSNPQYMNLPGIAVLIGGLWVANLYYWGFNQYIIQRTLAAKSVQEAQKGIVFAAYLKLIVPFLVVIPGIATYIITSNPELLSGLGSAAMTHMPSAAQADKAYPWLTQFLPVGIKGVVFAALAAAIVSSLASMLNSTATIFTMDVYREYIDPEAGDHKLVNVGRATALVALIIACFIAPMLGGIGQAFQYIQEYTGLVSPGILAVFLMGLFWKKTTSKGAIVGVLMSIPFALFLKLMPLSMPFMDQMLYTLLFTIVVIAFTSLSSTEGEEDPKGIALEAKLFKTESSFNLASYGIMVILAVLYAVFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z218</accession>
    <name>D0Z218_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Putative transport ATP-binding protein MsbA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">VDA_001867</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001867"/>
    <dbReference type="EnsemblBacteria" id="EEZ40835">
        <property type="protein sequence ID" value="EEZ40835"/>
        <property type="gene ID" value="VDA_001867"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1132">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034040">
        <property type="term" value="F:ATPase-coupled lipid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011917">
        <property type="entry name" value="ABC_transpr_lipidA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02203">
        <property type="entry name" value="MsbA_lipidA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 8 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <keyword evidence="1 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="68"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="1"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="166"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="200"/>
            <end position="207"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ40835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="406" mass="44563" checksum="1C75CC70B9E5048A" modified="2010-01-19" version="1">MVAISIRIVSKRFRKISRNMQDAMGSVTSSAEQMLKGHKVVLSYGGQEVERQRFDQVSNLMRRQTMKLVSAQAIANPVIQLIASLALVVVLVLANSESLRAELTPGTFAVVFGAMFGLMRPLKALTNVTSQFQRGMAACHTLFELMDLETEKDNGTHQVDTVRGDVSVKNVTFTYPTKDTPALRNVSFELPAGKTIALVGRSGSGKSTIANLMTRFYDIDSGEIQLDGINICDYELFNLREHVAVVSQNVHLFNDTIANNIAYASGDKYSREDIERAATLAHAMDFVKDMDNGLDTVIGENGVSLSGGQRQRIAIARALLRNAPILILDEATSALDTESERAIQAALDELQKDRTALVIAHRLSTIEKADQILVVDEGEIIERGTHDELIALDGAYAQLHRIQFGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2G6</accession>
    <name>D0Z2G6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hypothetical sensor histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000617</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304881.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000617"/>
    <dbReference type="EnsemblBacteria" id="EEZ39597">
        <property type="protein sequence ID" value="EEZ39597"/>
        <property type="gene ID" value="VDA_000617"/>
    </dbReference>
    <dbReference type="GeneID" id="57342897"/>
    <dbReference type="eggNOG" id="COG0642">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1827824at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021821">
        <property type="entry name" value="DUF3404"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11884">
        <property type="entry name" value="DUF3404"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019343" evidence="2">
        <location>
            <begin position="19"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="241"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="281"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="480" mass="55068" checksum="B6FA1472DF7B7D14" modified="2010-01-19" version="1">MKKYVLLMSLFLSSTSFADSMSLPERLSSIRGDLLKTEPLATYDIRQLQSRYPTPLLLPSSLLPQSAKYPLKALRQLYKQSLVCKGPWPVSPLVTQPVVFVRAMCFGTPLPRGWFVRAGYIHPGGGSYAYRYLEKHPQDNKKLDRYLHIKERPLAETNSILGRLQRMSDEEIKVFIAGSDAFIANGELWVRYDNDYKIYDQPTWSSVLNRYDVHFKRLNDNDFCLAKSGNICWQEEDKSHITYYLLVGLFVANLGILIGWGVLRLRSRRRAMQERMLVLQILTHELRTPIASLAMTVEGFRRQFDLLPEELYDEFRRLTEDSRRLRQLAEASKDYLQANQQELSVQEIESFNEWLEFLVEPYEVALTLPEQDRQVSLNMYWLGTCIDNLLSNATKYGVAPISLTASFNDGKVKIVVQDQGPLGKKDWARLRKPFVSERGLGLGLTIVESMIRRMGGTMRLDGPPTTFILEIPCESDSATG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-12-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2J1</accession>
    <name>D0Z2J1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Integrase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_000642</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304943.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000642"/>
    <dbReference type="EnsemblBacteria" id="EEZ39622">
        <property type="protein sequence ID" value="EEZ39622"/>
        <property type="gene ID" value="VDA_000642"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0582">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="745068at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0229">DNA integration</keyword>
    <keyword evidence="3" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyr recombinase" evidence="4">
        <location>
            <begin position="125"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="323" mass="37089" checksum="8B340BEA155B9C36" modified="2010-01-19" version="1">MAKKIPIIEDDHIKQHSIEQFKSIADTIELWQQLTHRMYADNTLVAFKNDWNMFISFCHQLNQCCLPASADVTCRFIEKMAQTRKLSSLKRYIVTIGLVHKCHALPNPCTSSDVKLAMFQQRMDKHDDYTQAQGFCDNHLQQLHTLFSSATKPKDVRDMAIWALTFEGMLKRSEVAALTVNDIEFIDNKSLITINSHLIELSELATEAVKKWLTLSLIETGFIFRRIDRHDNIGDSPLDHSSIYRVFRRASQELDLPVDVIFSGQSPRVGASQDLARSGLSIHQIQTQGRWKSPAMPAQYIGDRGYRDQELKHFAKKNQKDID</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2K2</accession>
    <name>D0Z2K2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Error-prone repair protein UmuC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_000653</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA polymerase type-Y family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000653"/>
    <dbReference type="EnsemblBacteria" id="EEZ39633">
        <property type="protein sequence ID" value="EEZ39633"/>
        <property type="gene ID" value="VDA_000653"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0389">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036775">
        <property type="entry name" value="DNA_pol_Y-fam_lit_finger_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017961">
        <property type="entry name" value="DNA_pol_Y-fam_little_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025188">
        <property type="entry name" value="DUF4113"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024728">
        <property type="entry name" value="PolY_HhH_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001126">
        <property type="entry name" value="UmuC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13438">
        <property type="entry name" value="DUF4113"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00817">
        <property type="entry name" value="IMS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11799">
        <property type="entry name" value="IMS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11798">
        <property type="entry name" value="IMS_HHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100879">
        <property type="entry name" value="SSF100879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50173">
        <property type="entry name" value="UMUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0741">SOS mutagenesis</keyword>
    <keyword evidence="3" id="KW-0742">SOS response</keyword>
    <feature type="domain" description="UmuC" evidence="4">
        <location>
            <begin position="9"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="430" mass="48880" checksum="DA237E00CBBAEFA8" modified="2010-01-19" version="1">MITRSKEVWALVDAKNFYCSCEQLFDPSLVGKPLVVLSNNDGCCVAISQQAKALGIVRGVPWFKIQREAIQQGVQVRSSNYTLYADMSRRFIEELSRFSPHVEQYSIDEAFIRLDGFQLNELADYGREIRTTILKNIGLPVRVGIGATPTLAKLGNHAAKVYEKQVRGVIQIDTEHRRQWLLERTPIQDIWGIGAKTATRLRTAGIQNGWQLAQQDSIDIRRLWNVTLARTVLELQQISCISPGDVEEKRKQILSSRTFGQGINQLDELNAALAFHCQRAGEKLRKQQSQTGVVGVFLRTNKHKSLPQHHRSAVMPLISATQDTYRILEVAQALLNEIYRGGYEYYKVGVILEQLTDVTDDAIQLDMFDSSALYESKRRELMAVADRVNARYKNGIKPASIISSTNWHMRQAHRSNRWTTRLDELPIARC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2M4</accession>
    <name>D0Z2M4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_000675</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305028.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000675"/>
    <dbReference type="EnsemblBacteria" id="EEZ39655">
        <property type="protein sequence ID" value="EEZ39655"/>
        <property type="gene ID" value="VDA_000675"/>
    </dbReference>
    <dbReference type="GeneID" id="57343019"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1020672at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="2"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="124"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="124"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ39655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="219" mass="24515" checksum="B15C13A0A723455D" modified="2010-01-19" version="1">MKILVVEDEIQLGEQIVAGLEQNSWVAELSTDGIDALYRATSEPWDAIVLDLGLPKLDGITVLKGIREENVDCPIVILSARSELTQRVEGLNAGADDYLTKPFQMVELVARLRAQLRRSTGNTSPVIQAGPLELDTRSSKVTFHGQPVELTALEFKVLSYLMHNQDKVISRTELVEHIYKQDFDRDSNTIEVFIGRIRRKVGTDVIKTVRGLGYRINAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2Q0</accession>
    <name>D0Z2Q0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000701</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305099.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000701"/>
    <dbReference type="EnsemblBacteria" id="EEZ39681">
        <property type="protein sequence ID" value="EEZ39681"/>
        <property type="gene ID" value="VDA_000701"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5266">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1382281at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019613">
        <property type="entry name" value="DUF4198"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10670">
        <property type="entry name" value="DUF4198"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019938" evidence="1">
        <location>
            <begin position="29"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="278" mass="31094" checksum="CE6C4473CCDCDBDD" modified="2010-01-19" version="1">MIYNKPLKALSLACLMASGLALSTAATAHPRWVLPSHFTVSKEGGDWLTFDVTASHGTFVFDKPAGSESAEVIMPDGRKERPNFVVRGKRRSMFDFFFVEEGTHKVQINQVPTYYTQYKAGRRDTVKWVKANKAERDSILPNKSRDVVTQMSFTRAETYINVGKPSVKAMELDGQLLEMKPLVHPADIIEGEPVTFQFYFNGKPQAGVTAEITREGTLYRNHQEQMDVISDAEGKVTFAPSMAGRYLMKANYKGELANNPLADTVSANVHFTFETQLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2R5</accession>
    <name>D0Z2R5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Iron(III) dicitrate transport system permease protein FecD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_000716</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305142.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000716"/>
    <dbReference type="EnsemblBacteria" id="EEZ39696">
        <property type="protein sequence ID" value="EEZ39696"/>
        <property type="gene ID" value="VDA_000716"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1283908at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037294">
        <property type="entry name" value="ABC_BtuC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000522">
        <property type="entry name" value="ABC_transptr_permease_BtuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30472">
        <property type="entry name" value="PTHR30472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01032">
        <property type="entry name" value="FecCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81345">
        <property type="entry name" value="SSF81345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="104"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="135"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="163"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="206"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="256"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="294"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="321"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ39696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="349" mass="37775" checksum="2920629704B426E7" modified="2010-01-19" version="1">MTAITDALKVHHARNRNKKVALAAFFVMSIVFLITDILIGSQGLTLHQVLSALFHPTSSSIASRIIVWDIRMPMSLMAPLVGAALALAGAQMQTTLHNPLADPYTFGISAAASFGASLIITNVIAIPWIPSQYQVAFMAFIMCLGTTFLIAGISTIKRISIEGVMLFGVAVMFAYDSLLAMMQYIASETQLQTLVFWHMGSLDRGSWGKIITLAIVLPIVIFLMMKDSWKLSTLKIGNERAETMGINVRRLRIKTLVLVSVITALSVSFVGAVGFVGLVAPHIARMILGEDQRFFLPASCLIGAVLLELASIASKAIMPGIILPLTVVMSFVGIPFFIFLIIKKGGKFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2Z6</accession>
    <name>D0Z2Z6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative transcriptional regulator CpxR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_000797</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000797"/>
    <dbReference type="EnsemblBacteria" id="EEZ39777">
        <property type="protein sequence ID" value="EEZ39777"/>
        <property type="gene ID" value="VDA_000797"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="15"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="130"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="130"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="232" mass="26598" checksum="C02FA2FC5E786F3C" modified="2010-01-19" version="1">MRMFFILLSVFVVSQIVVVDDDILLCSLLTEVLSDEGYDVESFHSGEDALNYMQDHSVDLVLLDVMLPKLNGMQVARRICQRFATPILMLTALNDESSMLDGLQAGADQFLAKPFKVPELLARITTILRRVGLERQRNLLVQKDNTELFKQFARIPLTTTESELLDYLVKRPDIVISKSELQKEVLKKDLCPFDRNLDMHISNIRRKMVKLGLSKQHIKTVRGKGYSFIERV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z309</accession>
    <name>D0Z309_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Membrane-fusion protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000810</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000810"/>
    <dbReference type="EnsemblBacteria" id="EEZ39790">
        <property type="protein sequence ID" value="EEZ39790"/>
        <property type="gene ID" value="VDA_000810"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1566">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HlyD_D23" evidence="2">
        <location>
            <begin position="81"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="241" mass="26765" checksum="D5601998BE238546" modified="2010-01-19" version="1">MQAKAGKSAAGALAEEAEKGARRQQVAAAQDQWRKASAAADLMEKTYRRIDNLYKDGVVAQQKRDEVYTQWQAAKYTESAAYQMYQMAKEGARVETKKAAQEKVKMAEGAVAEVQAYADDAKATSWHNGEVSQILLHDGELAPQGFPVVTIMDMSDAWAVFNVREDKLKDYQKGAELTVKIPALGEQEYRFKVTHVAVMGDFATWRATDTAKGFDMRTFEVEARPMEPIDGLRAGMSVIVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z322</accession>
    <name>D0Z322_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000823</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39803">
        <property type="protein sequence ID" value="EEZ39803"/>
        <property type="gene ID" value="VDA_000823"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="41" mass="4637" checksum="24CB00104451DCF3" modified="2010-01-19" version="1">MRLLFLSICLMIDENIGRFPIGSIIKKNITAAERVSIAYPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z347</accession>
    <name>D0Z347_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribosome biogenesis GTPase A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_000848</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000848"/>
    <dbReference type="EnsemblBacteria" id="EEZ39828">
        <property type="protein sequence ID" value="EEZ39828"/>
        <property type="gene ID" value="VDA_000848"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1161">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030378">
        <property type="entry name" value="G_CP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023179">
        <property type="entry name" value="GTP-bd_ortho_bundle_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019991">
        <property type="entry name" value="GTP-bd_ribosome_bgen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016478">
        <property type="entry name" value="GTPase_MTG1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006230">
        <property type="entry name" value="MG442"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03596">
        <property type="entry name" value="GTPase_YlqF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51721">
        <property type="entry name" value="G_CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1 2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CP-type G" evidence="4">
        <location>
            <begin position="5"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="286"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="51"/>
            <end position="54"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="117"/>
            <end position="122"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR006230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR006230-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="305" mass="34881" checksum="09ECE80250423CC6" modified="2010-01-19" version="1">MHKARKEIEEALPKVDVIIEVLDARIPFSSENPLIKRFREKNEKPVVKVLNKRDLADPEMTQRWIDHLEQEQNVKAIAITTDNINEVHQIMELCRKLVPHREEMGKNIRTMIMGIPNVGKSTIINTLAGRKVAVTGNQPAVTRQQQRINLQNGIVLSDTPGILWPKVENPHSGFRLAATGAVKDTAMDYIDVAFFTVEYLAQAYPDLLKARYNLDDELPDSEIELLEEIGRNRGCLQGGGRVDLHKVSEILINELRNGTLGKITMERPEMITQELIDVAVEAERKAEEKAKNKEERRKRYLRNKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z367</accession>
    <name>D0Z367_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF218 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000868</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305578.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39848">
        <property type="protein sequence ID" value="EEZ39848"/>
        <property type="gene ID" value="VDA_000868"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1434">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1879123at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06259">
        <property type="entry name" value="YdcF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003848">
        <property type="entry name" value="DUF218"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02698">
        <property type="entry name" value="DUF218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF218" evidence="1">
        <location>
            <begin position="26"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="215" mass="24172" checksum="82BD5F2342203CAA" modified="2010-01-19" version="1">MADRLYQHAQTIWDYHVLNHNLKPADCIVVLGSNDVRVAERAAELFHLGLSSKVLFSGGVGELTQNMFDCSEAEAFASIAMSLGVPQDAILIESRSTNTGENILFSQQLFDQERINPQSILLVQKPFMERRAFATAQVYWANKNLQVTSPRLSFGDYPNEILSFPDIVNVMLGDLQRIDEYPALGYSVKQDIPLDVWHAYEQLVALGFNGHLLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3C4</accession>
    <name>D0Z3C4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000925</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305735.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000925"/>
    <dbReference type="EnsemblBacteria" id="EEZ39905">
        <property type="protein sequence ID" value="EEZ39905"/>
        <property type="gene ID" value="VDA_000925"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1824968at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="197" mass="22644" checksum="17AA4193EA9F81AC" modified="2010-01-19" version="1">MKLKFIDSATFIAIFASYFYCIDTVYTNGYLSVFGLDNDLLERNFHQVIYSGFMRAYHGIFLGVGSLFLVFSVLALCKLNINFDFNPWRKAVFWFSAMIFMFGLIYVLSHYESNGIDDAKKWKKEIAKGHSSVVTIDKYKNELAYLYCGSKNCAGYDIKEQKIIYFPQTILAIRNKNITIKAIERKGKTASLDPTTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3D8</accession>
    <name>D0Z3D8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000939</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0381 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305780.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000939"/>
    <dbReference type="EnsemblBacteria" id="EEZ39919">
        <property type="protein sequence ID" value="EEZ39919"/>
        <property type="gene ID" value="VDA_000939"/>
    </dbReference>
    <dbReference type="GeneID" id="57343156"/>
    <dbReference type="eggNOG" id="COG3691">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1863819at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.860">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005272">
        <property type="entry name" value="CHP00743"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035571">
        <property type="entry name" value="UPF0234-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38769">
        <property type="entry name" value="PTHR38769"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04175">
        <property type="entry name" value="DUF406"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="99" mass="11030" checksum="B8B1DF9C1F4B4821" modified="2010-01-19" version="1">MTQDVQEYQTCEACGVSAEMGFIIKENDDVADVTIFANGKAALEAELANYLALAKEVNENFKFEVSPIEENSTELTARIQFECSAEKLIFELRSRSIAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3E6</accession>
    <name>D0Z3E6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sodium/dicarboxylate symporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_000947</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000947"/>
    <dbReference type="EnsemblBacteria" id="EEZ39927">
        <property type="protein sequence ID" value="EEZ39927"/>
        <property type="gene ID" value="VDA_000947"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3633">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001991">
        <property type="entry name" value="Na-dicarboxylate_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036458">
        <property type="entry name" value="Na:dicarbo_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42865">
        <property type="entry name" value="PTHR42865"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00375">
        <property type="entry name" value="SDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118215">
        <property type="entry name" value="SSF118215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="48"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="90"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="124"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="205"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="231"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="324" mass="33646" checksum="645EB08B90C2A879" modified="2010-01-19" version="1">MAALTAVVMSFLFPTTLTLVASNTGVAPPEGITEVINTLLFKIVDNPINALMTGNFIGILAWAIALGFALHQASDATKQVFHDMSNGVTLIVRFIIRLAPIGIFGLVANTFAETGFAALAGYAHLLAVLLGSMAIIAFIVNPAIVYYKTRQNPYPLVLKCTRESGITAFFTRSSAANIPVNMQLCKELDLHEDTYSVSIPLGATINMGGAAITITILSLAAVHTLGIEVDIATAVLLSIVAAVSACGASGVAGGSLLLIPLACSLFGIPNEIAMQVVAVGFIIGVIQDSAETALNSSTDVIFTAAACRAVERKKSEAPNLAPAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3H8</accession>
    <name>D0Z3H8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HNH nuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000979</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305896.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000979"/>
    <dbReference type="EnsemblBacteria" id="EEZ39959">
        <property type="protein sequence ID" value="EEZ39959"/>
        <property type="gene ID" value="VDA_000979"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1403">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1776909at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00085">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002711">
        <property type="entry name" value="HNH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01844">
        <property type="entry name" value="HNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00507">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNHc" evidence="1">
        <location>
            <begin position="214"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="278" mass="31780" checksum="AFFC5A78915398FA" modified="2010-01-19" version="1">MNTELIQKEILRRKNLFQKISYGDIATNVTPNKLRELQLYGGAAGIWVHSTVTKKIINNEFGIAVSILHTGKDYADDFSDCGILYDFPATNRRGSHDNNEIQALRNCYTAQIPLFVITKTKKKLRNVHIGLIKDFNEEKRKTYIEFVTNDTFIHNADINKIDYEQADYFTNFEQSVIKSLQDNPKKRRQRIEKANKKPQLISRVVKDYQRNPDIVAEALIRAAGICEACGCQAPFNKKSNGEPYLEVHHLIPLSKGGEDSLDNVQSLCPNCHRKLHFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3J0</accession>
    <name>D0Z3J0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Na(+)/(H)+ antiporter NhaC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_000991</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305928.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000991"/>
    <dbReference type="EnsemblBacteria" id="EEZ39971">
        <property type="protein sequence ID" value="EEZ39971"/>
        <property type="gene ID" value="VDA_000991"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1757">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="580055at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004770">
        <property type="entry name" value="Na/H_antiport_NhaC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018461">
        <property type="entry name" value="Na/H_Antiport_NhaC-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03553">
        <property type="entry name" value="Na_H_antiporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00931">
        <property type="entry name" value="antiport_nhaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="39"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="76"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="110"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="136"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="193"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="234"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="260"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="327"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="449"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="domain" description="Na_H_antiporter" evidence="7">
        <location>
            <begin position="161"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ39971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="482" mass="50652" checksum="A8F03FE69A09A1CB" modified="2010-01-19" version="1">MNNKSITAPPVGLALLPLIAMIGLLVIGYGVYGLPIESLLLTSAVIAAAVAWKIGYSWDDIQNAIIDRLAKTLPAVFILVLVGGLIGSWMVGGTIPMLVYYGLKIISPEYLVLTSFLVTCMVSLCTGTSWGSAGTIGVALMGIATGMDANLAAVAGAVVSGAYFGDKISPLSDSTNFAPVVAGTDLYSHIQHMLWTTIPAFILSAVVFFFVGSHDVTADTPEKVIAMLANIEQLFSLNIFLLLPPALILWGAIRKLPTIPLMLLAIAIGIFNAVTFQGFSLVTALTAMLNGFNASMFADAGLSNVTVVSDVLTLVNRGGMTSMMGVVLLVFCAFSFAGALALTGALNVLVDLLSKGIKGTASLIGATIVTTITVVCTTSDGKLALLIPSELFRDTYKRMQLDPKNLSRTIEDAGTIIEPLVPWTNAGVFMAATLGVSTLDYMPWAIQNYSAIFFAMLWAVTGVGIAKAVKETKTTTQTKATV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3K6</accession>
    <name>D0Z3K6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">D-octopine dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001007</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305969.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001007"/>
    <dbReference type="EnsemblBacteria" id="EEZ39987">
        <property type="protein sequence ID" value="EEZ39987"/>
        <property type="gene ID" value="VDA_001007"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0287">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="427052at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003421">
        <property type="entry name" value="Opine_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02317">
        <property type="entry name" value="Octopine_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Octopine_DH" evidence="2">
        <location>
            <begin position="194"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="369" mass="40173" checksum="9993CF54194A2D8C" modified="2010-01-19" version="1">MAPKVSIIGSGNAGLTAAYHFSLQGADVCLFGAKGFDQSLLDIEQNGGIEALAEFNSVPLTYAGFQAIDTVTRDLQTAVEYSDLLILPVPSFAQEPLFIDMLPHLKNGQIIMLMPGNYGSLVLNKIKNEHGYSDLDITFVDAISIPWATRIIGPAQLAILGMKEFLPVAAFPASQTQYAIEQLQAVMPLPLTPLKNVICAGLENINFGGHPLLTTLNMGLLENFDGQFNYYKDCCSISTAKAAAVMEQERQQVGQALGLDLRSELDAMNALYAMECETVYEVNRTSETHGKLNSAPNCASNRYITEDAAYLLVPCYEFAQLSGIETPIITSCLHIDNAYNDTNYFEQGRTLEKMGLAGLSIPQIMDFVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3N0</accession>
    <name>D0Z3N0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 9 10">Transaldolase</fullName>
            <ecNumber evidence="5 9 10">2.2.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">tal</name>
        <name evidence="11" type="ORF">VDA_001031</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 9 10">Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9 10">
            <text>D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = beta-D-fructose 6-phosphate + D-erythrose 4-phosphate</text>
            <dbReference type="Rhea" id="RHEA:17053"/>
            <dbReference type="ChEBI" id="CHEBI:16897"/>
            <dbReference type="ChEBI" id="CHEBI:57483"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="2.2.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 9 10">Carbohydrate degradation; pentose phosphate pathway; D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage): step 2/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 9 10">Belongs to the transaldolase family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.2" evidence="5 9 10"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306031.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001031"/>
    <dbReference type="EnsemblBacteria" id="EEZ40011">
        <property type="protein sequence ID" value="EEZ40011"/>
        <property type="gene ID" value="VDA_001031"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0176">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="784333at2"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00414"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004801">
        <property type="term" value="F:transaldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00957">
        <property type="entry name" value="Transaldolase_TalAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00492">
        <property type="entry name" value="Transaldolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001585">
        <property type="entry name" value="TAL/FSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004730">
        <property type="entry name" value="Transaldolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018225">
        <property type="entry name" value="Transaldolase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10683">
        <property type="entry name" value="PTHR10683"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10683:SF18">
        <property type="entry name" value="PTHR10683:SF18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00923">
        <property type="entry name" value="TAL_FSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00874">
        <property type="entry name" value="talAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01054">
        <property type="entry name" value="TRANSALDOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00958">
        <property type="entry name" value="TRANSALDOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 9 10" id="KW-0570">Pentose shunt</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0704">Schiff base</keyword>
    <keyword evidence="6 9 10" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="9">
        <location>
            <position position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ40011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="316" mass="34809" checksum="52DBF0F55733BD8E" modified="2010-01-19" version="1">MSTKLEQLRALTTVVADTGEIEAIAKYQPEDATTNPSLILKAAQIEQYAPLIDQAIEYAKAQSSDKTQQVQDACDMLAVNIGKEILTVVPGRISTEVDARLSFDTEGSIAKARKLIKMYNDAGISNDRILIKLASTWEGIRAAEVLEKEGINCNLTLLFSFAQARACAEAGVFLISPFVGRIMDWYKAKEGRDFAPQEDPGVISVTNIYNYYKEHGYNTVVMGASFRNTGEILELAGCDRLTISPQLLQDLEDATGVVEQKLLPATEVKARPAAMTHSEFLWEHNQDAMAVEKLAEGIRNFAIDQGKLETMIAEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3S3</accession>
    <name>D0Z3S3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">2-deoxy-D-gluconate 3-dehydrogenase</fullName>
            <ecNumber evidence="2">1.1.1.125</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001074</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.125" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306153.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001074"/>
    <dbReference type="EnsemblBacteria" id="EEZ40054">
        <property type="protein sequence ID" value="EEZ40054"/>
        <property type="gene ID" value="VDA_001074"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1294334at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008678">
        <property type="term" value="F:2-deoxy-D-gluconate 3-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011286">
        <property type="entry name" value="2-deoxy-D-gluc_3_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01832">
        <property type="entry name" value="kduD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="252" mass="26869" checksum="3A3930077046E1AF" modified="2010-01-19" version="1">MNNLFDLTGKVAIVTGCNTGLGQGMALGLAKAGADIVGVGHQAAPETQQQVEAMGRKFHYITANLMAQDHLEQIVAEAVEVMGHVDVLVNNAGIIRRQDILEFSEQDWDDVININQKTLFFLSQAVAKQFVKQGNGGKIINIASMLSYQGGIRVPSYTASKSAVMGLTRALATELAEHNINVNAIAPGYMATDNTAALRADEARNAAILERIPANRWGLPSDLEGPAVFLASSASDYVNGYTIAVDGGWLAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3X0</accession>
    <name>D0Z3X0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">PTS system N-acetylgalactosamine-specific IIC component</fullName>
            <ecNumber evidence="8">2.7.1.69</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_001123</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.7.1.69" evidence="8"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306277.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001123"/>
    <dbReference type="EnsemblBacteria" id="EEZ40101">
        <property type="protein sequence ID" value="EEZ40101"/>
        <property type="gene ID" value="VDA_001123"/>
    </dbReference>
    <dbReference type="GeneID" id="57343412"/>
    <dbReference type="eggNOG" id="COG3715">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1687744at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103111">
        <property type="term" value="F:D-glucosamine PTS permease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008982">
        <property type="term" value="F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004700">
        <property type="entry name" value="PTS_IIC_man"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03609">
        <property type="entry name" value="EII-Sor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51106">
        <property type="entry name" value="PTS_EIIC_TYPE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="38"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="98"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="181"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="208"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ40101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="260" mass="27454" checksum="362B39AE6A938535" modified="2010-01-19" version="1">MEISFIQAVMLGVLAFFAGLDLFNGLTHFHRPVVLGPLVGLILGDLPTGILVGGTLELIWMGLAPLAGAQPPNVIIGTIVGTSFAITTKVEPNVAVGVAVPFAVAVQMGITLLFSAMSAVMSKCDQFAQNADDKGIEKVNYMALAVLGTFYFLCAFLPIYLGAEHAENIVNAMPKELIDGLGVAGGIMPAIGFAVLMKIMMKNVYIPYFILGFVAAAWLQLPILAIATAATAMAVIDFMRKSEPTPMTTAPAQEDYEDGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3Z3</accession>
    <name>D0Z3Z3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Sodium/proline symporter</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Proline permease</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">VDA_001146</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the sodium-dependent uptake of extracellular L-proline.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-proline(in) + Na(+)(in) = L-proline(out) + Na(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:28967"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell inner membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306339.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001146"/>
    <dbReference type="EnsemblBacteria" id="EEZ40124">
        <property type="protein sequence ID" value="EEZ40124"/>
        <property type="gene ID" value="VDA_001146"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0591">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="231452at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="10" id="KW-0997">Cell inner membrane</keyword>
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        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="498" mass="53119" checksum="0679D4B0A10C8A84" modified="2010-01-19" version="1">MTVDSVAITGTFVAYLIVMLAIGYYAYKRTANSSDYFLGGRTLGPWPAALSAGASDMSGWLLLGLPGYAYVAGIESLWLAGGLLLGTWLNWLICAKRLRTYSITTDNALTLPEFLSRRFDDKSKLIQTISAFFILLFFLFYTSSGLVAGGKLFETVFGLDYSIAVIVGTICVVSYTLFGGFLAVSWTDLVQGLLMSAALVIVPIAAMNGGVSDLTAALEAKNPELLTLFNDVKGQPLSAIAIISLLAWGLGYFGQPHILARFKATRSNGDIATARRIAVVWTMLSMAGAILVGLTGMLYVDGQIGGSLADGEKVFMLLVNSLFHPVVAGILLAAILAAIMSTADSQLLVSSSALAEDFYKQVFRPQASSDEIVMVGRIAVIVLSIIALLLAMDPESSVLGLVSYAWAGFGAAFGPVLLLSLFWARMNRNGALAGIIVGAVTVVVWKQLTGGIFDLYEMVPGFIFASIAAIGTSLLTGEPSEKVKKQYQAYQQNLIEFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z459</accession>
    <name>D0Z459_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Metal-dependent hydrolase</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">VDA_000315</name>
    </gene>
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        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
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                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="YtcJ_like"/>
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        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
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        <property type="entry name" value="Metal_Hydrolase"/>
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        <property type="entry name" value="YtcJ-like"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018902" evidence="1">
        <location>
            <begin position="24"/>
            <end position="605"/>
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    </feature>
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            <begin position="106"/>
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    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
    <sequence length="605" mass="66868" checksum="99B7BC9934F490ED" modified="2010-01-19" version="1">MKGTPLKLSTLSIALFSILSLSGCDQTKNTAVKESKPQAVTQTEAEKQHEPDESAVFADTIYVNGDIVTINDKQPQVEAVAAKDGKIIAVGNKQDILKLKDANTEFFDLNRQTLIPGFVDAHGHVFNVGMQALSANLLAPPDGEIKDIDSLITTLDQWHKEHPERTDKVGWIVGFGYDNSQLAEQRHPTAEDLDKVSTELPVIAIHQSGHLAAVNTKALELAGINAETVDPEGGVFVRKPGTNEPNGTLEENAFYLVLGKMLENLTDQDNEKLFMAGMELYSQYGYTTGQEGRAFPNIMPVMEAVSARGSNPIDVVVYPDIVIASETISGPYLSKDYTDNFRIGGAKLTIDGSPQGKTAWLTQPYHVPPKGQNEAYVGYPAVSNAKTFEYVEQAYKNNWQILAHANGDAAIDVFIAAVKQAEAKYGKKDRRPVLIHGQTLREDQIVRLKQLDIFPSLFPMHTYYWGDWHRDSVLGPERAEFISPTNSVYQQGMKFSSHHDAPVALPDSMRVLSATVNRRSRSGDIIGPTERVSPLVALKAMTIWPAYQHFEEDRKGSIEVGKEADFVVLSENPLKIDPLNIENIRVQTTINDNAVVYQRENTNLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z483</accession>
    <name>D0Z483_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_000339</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EEZ39321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000339"/>
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        <property type="protein sequence ID" value="EEZ39321"/>
        <property type="gene ID" value="VDA_000339"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2199">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3452">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:catalytic activity"/>
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        <property type="project" value="UniProt"/>
    </dbReference>
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        <property type="term" value="P:organonitrogen compound metabolic process"/>
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        <property type="project" value="UniProt"/>
    </dbReference>
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        <property type="term" value="P:phosphate-containing compound metabolic process"/>
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        <property type="project" value="UniProt"/>
    </dbReference>
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        <property type="term" value="P:primary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
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        <property type="term" value="P:signal transduction"/>
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        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="CHASE_sf"/>
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    </dbReference>
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        <property type="entry name" value="Nucleotide_cyclase"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="257"/>
            <end position="280"/>
        </location>
    </feature>
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        <location>
            <begin position="105"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="6">
        <location>
            <begin position="316"/>
            <end position="448"/>
        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EEZ39321.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="449" mass="52064" checksum="906DC492A15A103E" modified="2010-01-19" version="1">MKVKRKIGNKVCVLAFFLYLCVLLMSYIISDKIINNREVFSNSRVEAYLNTALNDLGHDFKTEQEKLKWLSFYVASTGFNQKSFLLASDELLDGVKGSSNFQFAPNGVVTVTNPHVSDKRAYIDLFSDQNRKEDALYAKKHRTMYVSGPLNLYQGGLAFILRNPVFSLHRTQKFLGFVIYVSDISDSKIFSRISELSQYGYTVSLTTQYKQQAKNQILSTVDLKKDHYLFSINKTFYNSTWTMKIYSSNKMNDYQDLVLYITLLIDICIGIGLLLTIKFFEHYKNIHNERLLDHLTGLGNRKALELELSREFESKQDFSFVYIDLNDFKFVNDTYGHEIGDSLLRQFSARLNRYIWSHNLGMAFRVGGDEFNLIVAAKFDEESIRRGLDDLCKLPFQLDDVLYNLTISCGYAKRYPSDETLEQVIRRADDDMYRMKAIKKRPMTVMPIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z491</accession>
    <name>D0Z491_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_000347</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304111.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000347"/>
    <dbReference type="EnsemblBacteria" id="EEZ39329">
        <property type="protein sequence ID" value="EEZ39329"/>
        <property type="gene ID" value="VDA_000347"/>
    </dbReference>
    <dbReference type="GeneID" id="57343273"/>
    <dbReference type="eggNOG" id="COG1136">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1200451at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="4"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="39"/>
            <end position="46"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="219" mass="24374" checksum="9B87E37387F525BD" modified="2010-01-19" version="1">MLPASHHSLRFQSLRSGFEDPSLAFTDEVCSGQHLAIWGDSGCGKTSLIQVIASLKPAQQGEFYYQDRAITPLSFPWWRQQIGYLPQQPIMGGDTVEQVLLLPWQMQAMDKSIPLATPSQCEQALNQANLSVALSKEVNLLSGGEKQRLALARLLLMQRPVWLLDEPTSALDMSSRDHLIALVKESSAICISVSHDPIWYNAADMQYAMTVSPQHKELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-12-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4A7</accession>
    <name>D0Z4A7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative alpha-1,2-mannosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000363</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304157.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000363"/>
    <dbReference type="EnsemblBacteria" id="EEZ39345">
        <property type="protein sequence ID" value="EEZ39345"/>
        <property type="gene ID" value="VDA_000363"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3537">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="100818at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005887">
        <property type="entry name" value="Alpha_mannosidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041371">
        <property type="entry name" value="GH92_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012939">
        <property type="entry name" value="Glyco_hydro_92"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07971">
        <property type="entry name" value="Glyco_hydro_92"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17678">
        <property type="entry name" value="Glyco_hydro_92N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01180">
        <property type="entry name" value="aman2_put"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018906" evidence="1">
        <location>
            <begin position="21"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_92N" evidence="3">
        <location>
            <begin position="51"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_92" evidence="2">
        <location>
            <begin position="311"/>
            <end position="787"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="798" mass="88990" checksum="479814BD5187483B" modified="2010-01-19" version="1">MSFKLTPVALSIVLSFGLIGCNSDSSDSVFKPTPETSIPSTPIVDMSVLKFIDPMIGTAASGHTFPGSVVPRGMVQLSPDTFKGTNQDTEAGQNPWHSASGYWDASDYAKGDVFTTDLNIYGFSHTHLSGTGATDLGDILVLPYSDDNFRENNCFDKKNEIASPGYYSVILNEGKIKAELTTTTRVGVHRYTYEKGAERKIKLDLAHTLATNNGESLQNRIEMVDEYTIRGRRVSTGWFQGQDIFFYAKFNQPIVEALIARDGGQPTEMKMGAVYGSINSPNKEQITYLDFGQGDTPIEMRVALSPVDWEGAQKNLEVETPSYNFADVKAKAELAWAQELASVRVEGGTDTEKTNFYTAMYHAMIAPVEYQDVDGRYRDLLGGIHTADGYKNYSVYSTWDSFRAVHPLLTIVNPEHATALANDLIRKSQETGLLPKWEGYGEETGTMIGYPATAIIGDAVVKGLDVDPKAALEAAKKSAYYRPYDFPQIPDHTLQAVMAGQLSYYERDKCVGLPNWNSVSYALEFSYYDWTIGQMAKAAGDEDAYQEFNDRAYWSLNHWDTDAGFFVPVQLNSCEKEFESAKFDPYTSDAYWYTEGNAWQWQWTFMQDMDKLTEVMGGPVGFQQKLDALFAADPNGGHNHQDMTGFIGQYIHGNEPSHHVIYLYNRTATPWKAQEYLDKVYKEFYKPTPDGIIGNEDVGQMSAWYIMSAMGFYQVTPTDPTYTIGRPIFDKVVITLPDGDFTITADNNSAENKYVKSVLINGQPLNKFNTFEHSEIKAGGSLHFVMTADKSQAMSANM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4B8</accession>
    <name>D0Z4B8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">N-acyl-L-amino acid amidohydrolase</fullName>
            <ecNumber evidence="3">3.5.1.14</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000374</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.5.1.14" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304189.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000374"/>
    <dbReference type="EnsemblBacteria" id="EEZ39356">
        <property type="protein sequence ID" value="EEZ39356"/>
        <property type="gene ID" value="VDA_000374"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1473">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="796259at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004046">
        <property type="term" value="F:aminoacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017439">
        <property type="entry name" value="Amidohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11014">
        <property type="entry name" value="PTHR11014"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005962">
        <property type="entry name" value="Pept_M20D_amidohydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01891">
        <property type="entry name" value="amidohydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="2">
        <location>
            <begin position="178"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="383" mass="41768" checksum="AED12F65BF12AF27" modified="2010-01-19" version="1">MTIKNIVTEWRHHIHKHPEFGFEEEMTSAFVAQKLEEFGLEVHKNIGKTGVVGILKCGNSERSIGLRADMDALHICEKNTFAHASVHDGVMHACGHDGHTAMLLGAAYQLSQSKNFDGTVYFIFQPGEEHGVGAKAMIADGLFTRWNIDAVYAMHNLPGIPEGHFVTRPHSIMASESSFEIEVIATGGHAAMPHMGTDPIVVGSQIVLALQTIVSRHLSAIDETAVISVTEFATNGTVNVIPSRVTIKGDTRSFTDQALHKIEKAIERIVAGQCMAAGVDYKYNFNNSFLSTINTPEETDHAVKAALTVAGEDKVNGSCQPFTISEDFSFMLREAKGCYILVGNGVGECGGTALHNPHYDFNDNILMSGVNFWQTLVEQQLNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4C1</accession>
    <name>D0Z4C1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Metallopeptidase M24 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000377</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304196.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000377"/>
    <dbReference type="EnsemblBacteria" id="EEZ39359">
        <property type="protein sequence ID" value="EEZ39359"/>
        <property type="gene ID" value="VDA_000377"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0006">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="415910at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046914">
        <property type="term" value="F:transition metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_NTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000587">
        <property type="entry name" value="Creatinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001714">
        <property type="entry name" value="Pept_M24_MAP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01321">
        <property type="entry name" value="Creatinase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00599">
        <property type="entry name" value="MAPEPTIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="SSF53092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="SSF55920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Creatinase_N" evidence="2">
        <location>
            <begin position="17"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M24" evidence="1">
        <location>
            <begin position="168"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="388" mass="42992" checksum="6C1F0ED920252F80" modified="2010-01-19" version="1">MNDYLMRGFEQAEFEQRTARAQKVMRELELDAMLFTTEPNVRYFTGFHTQFWHSPTRPWFLVIPAEGKPTAIIPEIGASGMAGTWIDNIITWPSPRPEDDGISLVASFLNSLPCRFGRVGATLGIESHLRMPVNNYLKLTTLVKKSFVDVSLPMHEIRQVKSAAEIAKVKEICRITNVGFAKVPEYAKAGMTEREICKRFRIDMLMEGADECPYIIAGSGPDGYDSIIMGPTDRIIEEGDVLIIDTGAVRDGYFSDFDRNWAFGSASEQTKAAYRAVYEATTKGFEAAKPGATTTDIYNAMWSVLEANGALGNDVGRLGHGLGMELTERPSNTATDNTILKPGMVMTLEPGMVYAPGKSMVHEENIVITEDGAQWLSERAEPELIVIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4M7</accession>
    <name>D0Z4M7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Probable membrane transporter protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_000485</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39465">
        <property type="protein sequence ID" value="EEZ39465"/>
        <property type="gene ID" value="VDA_000485"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0730">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002781">
        <property type="entry name" value="TM_pro_TauE-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01925">
        <property type="entry name" value="TauE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="83"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="125"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="162"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="220"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="243" mass="26273" checksum="3114DB98A97D8B1B" modified="2010-01-19" version="1">MDSSIFLACLAIFTLGCFVQSSIGFGMGVLVGPFILVLEPQLMPSAVIFLGMSMSLIVWYQYRAYFEPKMLLSAFIGRLPGTVLAAYILMIVTADQLAIMLGVTVLIAVVLSLGKWKLSPTPVNMLIAGFVSGVMGTATGIGGPPLAILLQNEEPEKIRANLAAFFAITGVISLIALHLSGNFSYQDFHNSVLLLPAPIMATLLAYQVRHKIKKRLVHNSVLILCSVSAFVSLSRGMHLFHFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4P3</accession>
    <name>D0Z4P3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AAA_13 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000501</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304548.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000501"/>
    <dbReference type="EnsemblBacteria" id="EEZ39481">
        <property type="protein sequence ID" value="EEZ39481"/>
        <property type="gene ID" value="VDA_000501"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4694">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="538212at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026866">
        <property type="entry name" value="CR006_AAA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13166">
        <property type="entry name" value="AAA_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_13" evidence="2">
        <location>
            <begin position="16"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="84"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="720" mass="82674" checksum="5C52DAAA38B83788" modified="2010-01-19" version="1">MLTNIVLENVASYRSKSELRTDKKVNIIYGLNGSGKSTFSNYFYNPESTKYQQCSHRDSGDTVLVYNQKFIQDNFYAKDTLNGIFSLSKENKEAKEKVEAVTLELEEIAKDKQQIQREIGEQRSKINDAKDKAQKKIWEIKTNYAGGDRVLEFCLKGKMGGKEPLFNHLCSIPLPASKPSKTIADLKEEANAIDGDTAIKHSVLSKLGMFDLSADDLASLNEIIVGSEDSPVAKLIGKLKNSDWVSEGLKYLEQIEGSQCPFCQSETMTEHLAEQIRGYFDESYQNSVNEVKAIQARYSAIVESIPSLDDYKVTQFSTDYIAQLNEHYAKLSRDTEINLELIKQKVSNPSLQVVLTDVSESVEAFNLVVDSINKLISEHNAKIDNSANELTKIKAEFWRILRYEYDQTISNFNDVQNDANKVIADKTKEEAAKVALEEAKDVERAEHQKSTVNINDAIISINQGLTDIGITDFYIEKYEDELYRLVRTDSNSKIFSSLSEGEKMIISFLYFRELFKGKRSATEGQVKKVAVIDDPVSSLSHIFVYNIGQLIKNDFFNSENIEQVFILTHSLYFFYELADANHNRRKENQNLYRLSKNENGSSINTMKYEEVQNDYQSYWSVINDDKQPPALIANCMRNIIEYFFNFVQKADLSNVVQKPELKNPRFQSFVRYINRESHSLGQNIFDFKEFDYHDFKEGFRLVFEQTGYPEHYEKMSRIRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4Q7</accession>
    <name>D0Z4Q7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DNA-binding domain of ModE/molybdate-binding domain of ModE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_000515</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the ModE family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000515"/>
    <dbReference type="EnsemblBacteria" id="EEZ39495">
        <property type="protein sequence ID" value="EEZ39495"/>
        <property type="gene ID" value="VDA_000515"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2005">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032991">
        <property type="term" value="C:protein-containing complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030151">
        <property type="term" value="F:molybdenum ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015689">
        <property type="term" value="P:molybdate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016462">
        <property type="entry name" value="ModE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003725">
        <property type="entry name" value="ModE-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004606">
        <property type="entry name" value="Mop_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005116">
        <property type="entry name" value="Transp-assoc_OB_typ1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03459">
        <property type="entry name" value="TOBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005763">
        <property type="entry name" value="Txn_reg_ModE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00637">
        <property type="entry name" value="ModE_repress"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00638">
        <property type="entry name" value="Mop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51866">
        <property type="entry name" value="MOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 4 5" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Mop" evidence="6">
        <location>
            <begin position="125"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR005763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="267" mass="28850" checksum="CB1C7B315D9736AA" modified="2010-01-19" version="1">MSMKLDAQLTLFENGKTFANPRRIALLKAIAQTGSISQGAKVAGLSYKAAFDAVKDMNSRPEGPVIHSEKGGKGGGGAELTRLGQRVIQMYELLDKIQDMGLKALSDDNAPLDSLLGVMSRFSLQTSARNQLFGHISKVDRFDLHDVVTIELDSIHQVIATITHGSTIRLQLMEGKDAVALIKGPSIEVCLPSEIEAKGKNFDNQLLGTLISFSQDKEFTELELALSSDVTVCALVKNQQLPSTSLQIDMPLYALFASSQVTIATLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4S5</accession>
    <name>D0Z4S5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000533</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304647.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000533"/>
    <dbReference type="EnsemblBacteria" id="EEZ39513">
        <property type="protein sequence ID" value="EEZ39513"/>
        <property type="gene ID" value="VDA_000533"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1204683at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="6"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="195" mass="21802" checksum="62E91645AD640E27" modified="2010-01-19" version="1">MANTPKFDRQQVIDKATNLYWQKGFHATSMRNLQDAIDMRPGSIYASFGSKEGLFKQALQHYQQQGVIELNQCLANSASPLAGLKHFIQQLVLETPKSAPSGLCLLAKTVAELTCDNQELLDEACRLLNKMEAEFEKVIISAQQHGEITKEKNSAELARYVQVQIAGLRTYAKTHPNSDAISTMIDDIFAHYPFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4U9</accession>
    <name>D0Z4U9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type III secretion cytoplasmic protein (YscK)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000182</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306536.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000182"/>
    <dbReference type="EnsemblBacteria" id="EEZ39166">
        <property type="protein sequence ID" value="EEZ39166"/>
        <property type="gene ID" value="VDA_000182"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5032ECP">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1235056at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009510">
        <property type="entry name" value="T3SS_K"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06578">
        <property type="entry name" value="YscK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="221" mass="26060" checksum="FC6696F732FE4808" modified="2010-01-19" version="1">MVNSETQASQIQHQFNYCPCSYIDESWVMEKQPWLLKLQGWRDQAAINQWCIEDWALSPITDHTFYHPYNSLALLPVEATNRLLLMIGGIMHCQAMRQVVLKQPKQCLNQVFGVDETRFLIQQGPMMISNWPSGWQKPLPTSLDEKSFEKTAREQGYLWVKFLLAKSPSELVQRWQFKLDRQLTLTDRSADWLDNAHRDLAYRLIKKIAKQVIPQWFHLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4W9</accession>
    <name>D0Z4W9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Type III secretion inner membrane protein HrpY</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_000202</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the type III secretion exporter family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306592.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000202"/>
    <dbReference type="EnsemblBacteria" id="EEZ39186">
        <property type="protein sequence ID" value="EEZ39186"/>
        <property type="gene ID" value="VDA_000202"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4792">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1424100at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1690.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006307">
        <property type="entry name" value="BsaZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006135">
        <property type="entry name" value="T3SS_substrate_exporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029025">
        <property type="entry name" value="T3SS_substrate_exporter_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30531">
        <property type="entry name" value="PTHR30531"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01312">
        <property type="entry name" value="Bac_export_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00950">
        <property type="entry name" value="TYPE3IMSPROT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160544">
        <property type="entry name" value="SSF160544"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01404">
        <property type="entry name" value="FlhB_rel_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="83"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="140"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="187"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ39186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="352" mass="39052" checksum="23A099BB5EE07D65" modified="2010-01-19" version="1">MSGEKTELPTPKKLRDARQKGQVAKSQEVVSSALILALVAVLFAFADYYMSHISALLLLPSELAYQGFQDALLDVAIAIAKEMVYLLAPILIVAALIAIMSNMGQFGLLFSGESVKPDIKKINPVEGAKRIFSLKSIIEFIKSILKVSLLSCIIWVTLRDNLNTLLQIPACGLECVPTITGVLVKQLMIISSVGFIVIAAADYAYQKFDHTKQLKMTKDEVKREYKEMEGSPEIKSKRRQLHQELQASNQRDNVKRSNVLVTNPTHIAIGLYYKKGETPLPVITLKETDAMAKRMIAIAHEEGVPVMQKVPLARALYADGQLNQYIPGDLIETTAEILRWVASLEQSEESRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4Z6</accession>
    <name>D0Z4Z6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Amidohydro-rel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000229</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306670.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000229"/>
    <dbReference type="EnsemblBacteria" id="EEZ39213">
        <property type="protein sequence ID" value="EEZ39213"/>
        <property type="gene ID" value="VDA_000229"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2159">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1832218at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032465">
        <property type="entry name" value="ACMSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21240">
        <property type="entry name" value="PTHR21240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04909">
        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="2">
        <location>
            <begin position="56"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="344" mass="39203" checksum="4924EE6443A480BD" modified="2010-01-19" version="1">MKQKKYKKIAVEESWMPTELFEEFMKLSQEKCVDPGFLSLWGEIMMSSNAEKLKNLICDINNNRIKKMDDVGIDIQILSLTAPGVQIFEKDKAVKMARFCNDKLAEEIKINPERFIGLATVAPQDPIEAAKELERCIGQLGMKGVIINSHTNGEFLDNKKFWPILKVAEKLDVPIYLHPNTPCSAMIDPYTELPLEGAIWGFAADCGLHALRMILGGVFDQFPKLKVVLGHLGEGIPWFINRIDNQYDTFVQDASESPRAKKLKRTPKEYFLENFYITSSGMNWELEIMYSLAIVGEDNILFAVDYPFSMPEPAIENVDKLPISDDFLIKFYQKNAENVFSLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z511</accession>
    <name>D0Z511_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chromosome partitioning protein ParA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000244</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306714.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000244"/>
    <dbReference type="EnsemblBacteria" id="EEZ39228">
        <property type="protein sequence ID" value="EEZ39228"/>
        <property type="gene ID" value="VDA_000244"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1192">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1631847at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002586">
        <property type="entry name" value="CobQ/CobB/MinD/ParA_Nub-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01656">
        <property type="entry name" value="CbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CbiA" evidence="1">
        <location>
            <begin position="5"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="218" mass="24432" checksum="40D4ABF180AB9438" modified="2010-01-19" version="1">MGKVILLAHQKGGVGKSNTATNLAVAIAKEKFKGSSDQILLVDADPQATLYRWAQRREECDAIQSFPCIRLDGNITSQIKRESEKYDYVIIDAAGRDSREMRSAMLSADLMLMPTKASLADLELLEHMSETVEIARDYNPDLAVCVFINMAPTNTQTEKVLAKQLLREFPEFKLLNTVLSERKSHRDAFSEALGVHEWKDSKSKAEVSCLLKEVLDEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z546</accession>
    <name>D0Z546_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Flp pilus assembly protein RcpC/CpaB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000096</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306835.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000096"/>
    <dbReference type="EnsemblBacteria" id="EEZ39080">
        <property type="protein sequence ID" value="EEZ39080"/>
        <property type="gene ID" value="VDA_000096"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1735229at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017592">
        <property type="entry name" value="Pilus_assmbl_Flp-typ_CpaB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031571">
        <property type="entry name" value="RcpC_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16976">
        <property type="entry name" value="RcpC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03177">
        <property type="entry name" value="pilus_cpaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RcpC" evidence="1">
        <location>
            <begin position="119"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="267" mass="29045" checksum="23B9166D5EE42916" modified="2010-01-19" version="1">MKSKLILAFAIIVILFGLYGLATNLSNPTSPANHEPIKEEPKIRVWKLNKDVHPGEFIERNMLSVENIPESEANGLGFVDDVNLDWKAKTVFKSHLSAGSLLTIDDLVQPDQDGYIDFIIDENKIPFPIIVTPSSVIGGVIANGSLVDILALTGLNGTASNFGNNSGSSKNTVSITPIISAVKVLLVKHQLIDTNRQSDTSDEQVTLVVELTRKQAVVLTVAQRISEIEVHKSSGYYNTDDLSADAGDILKNFKAITEYRADTTTVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z551</accession>
    <name>D0Z551_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Type II/IV secretion system protein TadC associated with Flp pilus assembly</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_000101</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306849.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000101"/>
    <dbReference type="EnsemblBacteria" id="EEZ39085">
        <property type="protein sequence ID" value="EEZ39085"/>
        <property type="gene ID" value="VDA_000101"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2064">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1559784at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018076">
        <property type="entry name" value="T2SS_GspF_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00482">
        <property type="entry name" value="T2SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="267"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="7">
        <location>
            <begin position="155"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ39085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="293" mass="33221" checksum="694C497447F09849" modified="2010-01-19" version="1">MNESTLIFIAMASIFFGIAIILWMIISKVSKQDIYTDFAIVPSSNVHNKTNSLEELKKYLPSALSADVKEIDKKFYSAGFYDFKYAYLYMPIKYLLVLIGSGSIYWFSKGIFDNPTMMAIICVWVVLCISMPDIVLAQKSKTLRHKISGQLPYLLDLLAMCVQTGMTIESSMSYLSREMKGFDRDLSHLLTRTNDRARIIGLEQALDELYIRVPTNEMRSFVMTIKQSLQYGSSIYNILTTLAADIRDMRMLTLEEKIGKLAAKMSIPLILFILIPIVILIAAPGVLRMLQNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z560</accession>
    <name>D0Z560_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Quinoprotein amine dehydrogenase beta chain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306877.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000110"/>
    <dbReference type="EnsemblBacteria" id="EEZ39094">
        <property type="protein sequence ID" value="EEZ39094"/>
        <property type="gene ID" value="VDA_000110"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1303819at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003020104" evidence="1">
        <location>
            <begin position="21"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="487" mass="53934" checksum="B5FACECA1741C22A" modified="2010-01-19" version="1">MKSKKKVLLCAMITTLSACNGGGDDAPSIEGKLTNKDKAISTSKTISPSVDGKLDEKDKKIIPSDLTKSLTSTLMPQLGLTKIRNLKISPNSQFLAVSNDDEDTKNGRVNIYQQHQGQWKLINKLTPSADSRSSLFGNSMAFSRDGKTLSIGSYYASEGGLSNIGKVYLYKFDGENFKVEQNIQPLSLVANANFGRHVNLSADGQTLLVSAPQQKSVRCTNEYSPCGTVYVYKYDPNQAQWNMASEFDGPDNDTYFGYDMALSGDGSTAIISNLGSKLSWYSLKNKQHPERVQTLDLPKMVSSVALNQNGLVTAFSDNNSTVYLYTKKEGTYKLETTIEKPISDELYYKDWQNYSSNGYDFGSDIALNSDGTVLVATSFNDDFNHFGATSLSDTLLTNVVSTDNKQECPGKYGPSRIFTGASFVYLRQNQKWNLTQYLKPPKIEDNQFCTKGYNGPNRLDNDRIVVTVSDDNKIFQSTIGNRIVEYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z568</accession>
    <name>D0Z568_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">OMP_b-brl domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000118</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306901.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000118"/>
    <dbReference type="EnsemblBacteria" id="EEZ39102">
        <property type="protein sequence ID" value="EEZ39102"/>
        <property type="gene ID" value="VDA_000118"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3637">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2059638at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027385">
        <property type="entry name" value="OMP_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13505">
        <property type="entry name" value="OMP_b-brl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003020041" description="OMP_b-brl domain-containing protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="OMP_b-brl" evidence="2">
        <location>
            <begin position="12"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="190" mass="21184" checksum="7B768DF3401B70B5" modified="2010-01-19" version="1">MSNLLRLCIISSLFTASATTWAATPSNVIGLNLGYGGLNASTKLKDFDSSDLFDGDLYYRRMFNENFGLEVGYRSSTGGLGSMLISPLTKITDISYYGPHTDLYAYYPLTGGFSLYGKVGINYYKLDYTYQTNIEGKKQQHRITDSELGGEVAAGVEWRYEWLGFNLGYMYSKSDLIETSGIQFGTSIHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z590</accession>
    <name>D0Z590_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mutator family transposase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_000140</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">Required for the transposition of the insertion element.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the transposase mutator family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39124">
        <property type="protein sequence ID" value="EEZ39124"/>
        <property type="gene ID" value="VDA_000140"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3328">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001207">
        <property type="entry name" value="Transposase_mutator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33217">
        <property type="entry name" value="PTHR33217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00872">
        <property type="entry name" value="Transposase_mut"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01007">
        <property type="entry name" value="TRANSPOSASE_MUTATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0814">Transposable element</keyword>
    <keyword evidence="4 6" id="KW-0815">Transposition</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="269" mass="31484" checksum="08837026F14EF07B" modified="2010-01-19" version="1">MMLISKVTDSVLEQVIEWQSRLLDEVYPIVYLDCIVIKVRQDKQVINKAVYLALGVNMEGQKELLGMWLSETEGAKFWLNVLTELQNRGVKDILIACVDGLKGFPDAINTVFPETQIQLCIVHMVRNSVKYVPWKDYRAVTADLKKIYQSATEDEALLALEQFSARWDSKYPQISRSWTTHWDNLNTLFSYPEDIRRAIYTTNAIESLNSVIRKAIKKRKLFPTDESARKVIYLAIRDASKKWTMPIRNWRQALNRFMIMFEDRLSEYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5B5</accession>
    <name>D0Z5B5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Chaperone protein FanE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_000022</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the periplasmic pilus chaperone family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000005">
        <property type="protein sequence ID" value="EEZ39037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000022"/>
    <dbReference type="EnsemblBacteria" id="EEZ39037">
        <property type="protein sequence ID" value="EEZ39037"/>
        <property type="gene ID" value="VDA_000022"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3121">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061077">
        <property type="term" value="P:chaperone-mediated protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008962">
        <property type="entry name" value="PapD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036316">
        <property type="entry name" value="Pili_assmbl_chap_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001829">
        <property type="entry name" value="Pili_assmbl_chaperone_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016148">
        <property type="entry name" value="Pili_assmbl_chaperone_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018046">
        <property type="entry name" value="Pili_assmbl_chaperone_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016147">
        <property type="entry name" value="Pili_assmbl_chaperone_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02753">
        <property type="entry name" value="PapD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00345">
        <property type="entry name" value="PapD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00969">
        <property type="entry name" value="CHAPERONPILI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49354">
        <property type="entry name" value="SSF49354"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49584">
        <property type="entry name" value="SSF49584"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00635">
        <property type="entry name" value="PILI_CHAPERONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0574">Periplasm</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018956" evidence="7">
        <location>
            <begin position="23"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="PapD_N" evidence="8">
        <location>
            <begin position="24"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="PapD_C" evidence="9">
        <location>
            <begin position="162"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ39037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="231" mass="25778" checksum="99EF821C80D9771D" modified="2010-01-19" version="1">MKTKIMTALLLALCTFSQSASAAFVLNGTRYIYDEGRKNISFEITNQSKETYGGQVWIQNTSLPKSEVAFVPIPSFFKVDGKQTQVVRIMKITDKLPKDKESLFWLNVQEIPPINKDQNNIMVIAVNTQVKLIYRPTLLIKGRENAEAKMTLKKVGDSYALNNPTPYYFAVTALKVNGKAIKLSTTLGNELGMIAPQSSILLKGIKLMPSSKVEIEAIDDYGAVNDYKVKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5E8</accession>
    <name>D0Z5E8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chromosome (Plasmid) partitioning protein ParA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000055</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000005">
        <property type="protein sequence ID" value="EEZ39070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005307092.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000005.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000055"/>
    <dbReference type="EnsemblBacteria" id="EEZ39070">
        <property type="protein sequence ID" value="EEZ39070"/>
        <property type="gene ID" value="VDA_000055"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1192">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="729012at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025669">
        <property type="entry name" value="AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13614">
        <property type="entry name" value="AAA_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_31" evidence="1">
        <location>
            <begin position="10"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="266" mass="30340" checksum="45336E40CB704742" modified="2010-01-19" version="1">MTISIKPLTRIIMIGCRKGGVTKTTTTINLGYELSQQGKRVLVLDFDGQGDSTKFYGREDSEYYIGDALLDRKFDINNAIYPAIINDIEQENLHIIPGRRGDIMTKLDMDMISLTRREERLKLHLDKIKDRYDFILIDTNPGTSVLGLNAVMAATEYLFPTEYKEHSLDGVETLLEHIQDVKFVEEDEIKFLVVPSKISKTAKKALDYGIGYLAERWPNNTAKTTIWDRSLFTESEMEHEPASVVNRGHVAARYYKELAKEVIANV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVJ2</accession>
    <name>D0YVJ2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">3',5'-cyclic-nucleotide phosphodiesterase</fullName>
            <ecNumber evidence="5">3.1.4.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001572</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the cyclic nucleotide phosphodiesterase class-II family.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.17" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298304.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001572"/>
    <dbReference type="EnsemblBacteria" id="EEZ40546">
        <property type="protein sequence ID" value="EEZ40546"/>
        <property type="gene ID" value="VDA_001572"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5212">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1712770at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004115">
        <property type="term" value="F:3',5'-cyclic-AMP phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006198">
        <property type="term" value="P:cAMP catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07735">
        <property type="entry name" value="class_II_PDE_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024225">
        <property type="entry name" value="cAMP-PdiesteraseII_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000396">
        <property type="entry name" value="Pdiesterase2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28283">
        <property type="entry name" value="PTHR28283"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02112">
        <property type="entry name" value="PDEase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000962">
        <property type="entry name" value="Cyc_nuc_PDEase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00388">
        <property type="entry name" value="PDIESTERASE2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00607">
        <property type="entry name" value="PDEASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0114">cAMP</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019820" evidence="4">
        <location>
            <begin position="20"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00025762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR000962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="327" mass="36195" checksum="6850E519E1D369C6" modified="2010-01-19" version="1">MVRKLIAAMLCCYSTLSYSGFDVVTLGAKGGIQDGNLTAFMLKSNSDDNYITLDAGSLVNGLRAAVQKEAFNDLTVPPTCDYNEVGYLLNKKIKGYFISHGHLDHIAGLIISSPDDSSKTIYALPSVHQTISQHYFNWKAWPNFTNQGEGYKLNKYVLTPLSTSGWQQVKGTELKVKTFPLSHSGIESSAFLFENSAKEAVIYLGDTGPDSVENSQSLDTIWKQLAPYINARQLRGIFIESSFSNSTPDKALFGHLTPNWIQAELNKLASYTDNPQAIAGLNVVITHIKYSLKQGPDPKFVIQRELNENNPLGINFIFTEQGDRIKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVJ5</accession>
    <name>D0YVJ5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative preprotein translocase SecA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001575</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001575"/>
    <dbReference type="EnsemblBacteria" id="EEZ40549">
        <property type="protein sequence ID" value="EEZ40549"/>
        <property type="gene ID" value="VDA_001575"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3012">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3318">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004027">
        <property type="entry name" value="SEC_C_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011978">
        <property type="entry name" value="UPF0149"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036255">
        <property type="entry name" value="YgfB-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02810">
        <property type="entry name" value="SEC-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03695">
        <property type="entry name" value="UPF0149"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101327">
        <property type="entry name" value="SSF101327"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="194" mass="21451" checksum="F3C312D8AF626359" modified="2010-01-19" version="1">MSATFIEGALFAANSNPKPMEPEVWLPELLGSDVALSDDDKTLILNHFELQYRTVKAGEYQLDPTLVWAEENRANLAQFAQGFLSVWQHIEPNWAEQPINDGTMRMLSALLTTLMLLVDEEETRAQMQEAGIDAMPELEILCQQLSLMLTEVMMAGDELQIGAGAQAVNPFKDVGRNDACPCGSGKKFKQCCGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVR3</accession>
    <name>D0YVR3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HNH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002004</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299153.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40972">
        <property type="protein sequence ID" value="EEZ40972"/>
        <property type="gene ID" value="VDA_002004"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00085">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002711">
        <property type="entry name" value="HNH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01844">
        <property type="entry name" value="HNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNH" evidence="1">
        <location>
            <begin position="60"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="276" mass="32138" checksum="4BF25675B9E479AF" modified="2010-01-19" version="1">MRYINRNSIQVPQKLATLYANQAEFDNAKQAIANGTDIRKGLYRHDSVKLALETLYKDVCFLCQKSVKDNYDVEHLLPWSKHFPERAYDWENLHQSCKECNQKKKRHTYKELDTTDHNKVIDILLLDPTRAQVDQFITFDPFTSESVVTERGNTVLKAQTTTHFLNSSDYVLARKAHWDAIRDIFTSEEWFDAYRKLRSEYRNHNVINLNFADELDSKVGSLCYRIATGFLGLNRPYNMFVARVMNQNIKVNPYAIKHFAQQHCVNVGSLLPALVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVX8</accession>
    <name>D0YVX8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sigma factor RpoE negative regulatory protein RseB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_001259</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RseB family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297745.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001259"/>
    <dbReference type="EnsemblBacteria" id="EEZ40237">
        <property type="protein sequence ID" value="EEZ40237"/>
        <property type="gene ID" value="VDA_001259"/>
    </dbReference>
    <dbReference type="GeneID" id="57339853"/>
    <dbReference type="eggNOG" id="COG3026">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1490766at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd16327">
        <property type="entry name" value="RseB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033436">
        <property type="entry name" value="MucB/RseB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038484">
        <property type="entry name" value="MucB/RseB_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033434">
        <property type="entry name" value="MucB/RseB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005588">
        <property type="entry name" value="MucB_RseB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38782">
        <property type="entry name" value="PTHR38782"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03888">
        <property type="entry name" value="MucB_RseB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17188">
        <property type="entry name" value="MucB_RseB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005427">
        <property type="entry name" value="RseB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0574">Periplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019757" evidence="5">
        <location>
            <begin position="23"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="MucB_RseB" evidence="6">
        <location>
            <begin position="29"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="MucB_RseB_C" evidence="7">
        <location>
            <begin position="219"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ40237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="326" mass="36578" checksum="EB2B622BEAC7C704" modified="2010-01-19" version="1">MKKFLVGAFALVSLAMPLQASAEGITASSEALLHQMDEASQNLNYELSYILIKKNSIEPLRYRHALENGEPYAHLMYLSGPPREVIQRGNEVSYFEPGIDPFTIESNKMVAPLPPVMGTDLKSLAQSYDFISMGKAREAGVACDVVRIAPKDGLRYSYLLWIDQKNHLVMRADLLDRDGEPLEQYRVVAFVINSRVQQILKQLQTVELPAVVHLPPQQKQNLDWKVDWLPQGFEAMSGSRHRLMLTERPVESKMFSDGLFSFSVYVSSIDNYTVREQLVRQGRRTLTSVAMGNKEVTVVGDIPPSTARRVADSVVFNATSAQDTTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW96</accession>
    <name>D0YW96_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional repressor for pyruvate dehydrogenase complex</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001193</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297609.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001193"/>
    <dbReference type="EnsemblBacteria" id="EEZ40171">
        <property type="protein sequence ID" value="EEZ40171"/>
        <property type="gene ID" value="VDA_001193"/>
    </dbReference>
    <dbReference type="GeneID" id="57339952"/>
    <dbReference type="eggNOG" id="COG2186">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1875458at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011711">
        <property type="entry name" value="GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008920">
        <property type="entry name" value="TF_FadR/GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07729">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00035">
        <property type="entry name" value="HTHGNTR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00895">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48008">
        <property type="entry name" value="SSF48008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="4">
        <location>
            <begin position="9"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="257" mass="29661" checksum="11EDF4A06ED2D38F" modified="2010-01-19" version="1">MTYKRIRQPKLSDAIEQEIEQLILDGILSPGQQLPPERELAKQFEVSRPSVREAIQRLEAKHLLTRRQGGGTFVSEKLWQSFSEPLLDLLASHPEAQLDLLESRHALEGLAAYYAALRGNEEDFNRIRHCHQRIQEAQQQGDLPAEASAVMQYLITVTESAHNVVLLHIIRSLAPLLEQNVLQNFERLNRDPKIVEKVRNHRANIVHAIVSGLPEQAREASHAHLAYIEETLLELTRQESRRERSLRRIQQRKERLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWG8</accession>
    <name>D0YWG8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribosomal silencing factor RsfS</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rsfS</name>
        <name evidence="3" type="ORF">VDA_001427</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Interacts with ribosomal protein L14 (rplN).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the Iojap/RsfS family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298041.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001427"/>
    <dbReference type="EnsemblBacteria" id="EEZ40401">
        <property type="protein sequence ID" value="EEZ40401"/>
        <property type="gene ID" value="VDA_001427"/>
    </dbReference>
    <dbReference type="GeneID" id="57339648"/>
    <dbReference type="eggNOG" id="COG0799">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1990650at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042256">
        <property type="term" value="P:mature ribosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090071">
        <property type="term" value="P:negative regulation of ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017148">
        <property type="term" value="P:negative regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01477">
        <property type="entry name" value="Iojap_RsfS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004394">
        <property type="entry name" value="Iojap/RsfS/C7orf30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21043">
        <property type="entry name" value="PTHR21043"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00090">
        <property type="entry name" value="rsfS_iojap_ybeB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="2" id="KW-0810">Translation regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="105" mass="11889" checksum="9E060D4CB1243A5F" modified="2010-01-19" version="1">MQVQELHDFIVDKVDDIKAQDIVTVDVRGKSSITDMMVICTGTSNRHVASIADHVKKESKLIDYPPFGISGEEDGEWVIVDMGNVMLHVMQEDARQLYQLEKLWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWM2</accession>
    <name>D0YWM2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001513</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298191.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001513"/>
    <dbReference type="EnsemblBacteria" id="EEZ40487">
        <property type="protein sequence ID" value="EEZ40487"/>
        <property type="gene ID" value="VDA_001513"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1216">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1379602at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="325" mass="38190" checksum="DF8EE0637D1480C8" modified="2010-01-19" version="1">MKLQSIKVKAYKLFISFPFLVGIKNIVKNTINSISNSDKKNIEILEVARKEINSKKCSLKYPPLLIMTTFNDHDIIESIILKNMEAGLEQIIIDNWSSDGTWTIIEELRKKYPKKITAFHYPFEGPTSNFMWRAMLDLKTNIALHHKGRWIIHQDSDEYTIPPIKGIQLGDFLSFVEQEGFNCVSLRMLDFVPLNDDFTIGNPISHFKNYRISDIPSYIIQNKIWLQGDDKVDLVSSGGHNVFFKGRKIFPLRLPRFHYSIRSIEHAKSKYSPKRAERVKEEQEVLGWHGHTDFKIKEKVIYKEDETIRYHFDDLYTKKIKLFKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWQ2</accession>
    <name>D0YWQ2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein SirB1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001448</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0162 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298077.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001448"/>
    <dbReference type="EnsemblBacteria" id="EEZ40422">
        <property type="protein sequence ID" value="EEZ40422"/>
        <property type="gene ID" value="VDA_001448"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2912">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1023028at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032698">
        <property type="entry name" value="SirB1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13369">
        <property type="entry name" value="Transglut_core2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transglut_core2" evidence="2">
        <location>
            <begin position="34"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="269" mass="31233" checksum="EEAB8AE4CF3A3DC0" modified="2010-01-19" version="1">MLQFTEDELEQMPLVEGAIEMTSRIDPSFPATWVHLQLENLAKEAEHELMDEINPQLRLEGLLRLFYHQWGFCGDHQQYFSSDNVYLDKVLERRKGIPVTLGSIFIYLAQRLDLPVVGVGFPTQFVMKVTWYDGEILFINPFDGEYVSRHILSSWLIGHRGPFTQLDPEFLETTTHQETLYRWLTVFKSAFLREEQFMTALACSDLALLINPEDPHEIRDRGYIYQQLDCCHAAAEDYSYFIEQCPEDPAADLLKLQVQALNAEPLTLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWT1</accession>
    <name>D0YWT1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001476</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40450">
        <property type="protein sequence ID" value="EEZ40450"/>
        <property type="gene ID" value="VDA_001476"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="39" mass="4250" checksum="2AAF10CA4ADC2A57" modified="2010-01-19" version="1">MTEQEPVTKIQHTAPISIGIMAILVAFVVIMISANTHPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-06-02" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWZ7</accession>
    <name>D0YWZ7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative portal protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299279.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002050"/>
    <dbReference type="EnsemblBacteria" id="EEZ41018">
        <property type="protein sequence ID" value="EEZ41018"/>
        <property type="gene ID" value="VDA_002050"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5511">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="274441at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019068">
        <property type="term" value="P:virion assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006429">
        <property type="entry name" value="Phage_lambda_portal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05136">
        <property type="entry name" value="Phage_portal_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01539">
        <property type="entry name" value="portal_lambda"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="459"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="495" mass="56344" checksum="C8474376C289AD1D" modified="2010-01-19" version="1">MSRLNFADRIICYLSPKAGAKRLYNRTLVNKYQAALPANPHSKKRNPRSTGLANQVNRDAKSLRERARHMDENTPYVTAILDELCANVVGPNGIMIEPQPLDMNGNVHTEFARKISEWFEVFSLTQNIDGELSRAETEWLACRTWLRDGEVFARYYMGENIELEYPSETPFGVQPFEPDYIPFHINEPERGVFEGIRRNRLGQMISILIQRDQHGFAFSEVSASFIAHLKFTRRFHQNRGVTLLHSVLDLISDIEDYDQSERISAQIASRFAYFIKRDSTSNGDDDFDRGGDIFLGMGNSFELAPGEDAGIVESRRQESMSSPFRDAQMRLAASGSGVNCSSVTRHYTGSYSAQRQELIDSFARYRILQRKFVTSWTRPQYRMALQMAILSKVLTVPKGVDPNSILNAIYQAPVMPWIDPAKEMTGIEKGTRLGLQSLSHFQRERNYNPVAVRREIKSERQAMNDDDIVSTADPAHNLQSKIQHSTKEASDGQKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX01</accession>
    <name>D0YX01_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Baseplate J-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002054</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299293.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002054"/>
    <dbReference type="EnsemblBacteria" id="EEZ41022">
        <property type="protein sequence ID" value="EEZ41022"/>
        <property type="gene ID" value="VDA_002054"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3948">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1656613at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006949">
        <property type="entry name" value="Baseplate_J-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04865">
        <property type="entry name" value="Baseplate_J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Baseplate_J" evidence="1">
        <location>
            <begin position="115"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="325" mass="37108" checksum="5AC081CE6E8C5D54" modified="2010-01-19" version="1">MSLPKAFVVPEFESLLNEYIQFAVSYCAKGDADKAKVLNEAMTNDSELLAQMVQAFIIKRIAEIREQNHQSLQMFRKFVTESDMVDLLALQYGLKRQVLEAGNDLVFPPKPPVMESDQSLLQRFDLAPYQFHTTGTRMGYKFHALTLDERPLIKIESEDNAVVMRYEFQDLTRPMPVKDAMPQMLEPNSGKVCVAVLSRENPRGIADEALLTRVRHYLQRDDIGQESDEITTKSAIAKDYRIEVTVYTGSDPGSHVEQSKAEQVAWDLAHKRHQLKGIIDREEVAHIFYQLGAKRAKVHEPAQDIICQWDEAPYCTEVIIHVRGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX10</accession>
    <name>D0YX10_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002067</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41035">
        <property type="protein sequence ID" value="EEZ41035"/>
        <property type="gene ID" value="VDA_002067"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="197" mass="23373" checksum="BC2409EF218C5260" modified="2010-01-19" version="1">MEEWCSLIIFSIRDMLNMFFVNHNIKIKYYISNGLMMRSDVIKFTLDAVNDIGINSDWSTSDWTRKIKNDLCRLGKEQGFWVYASSCDESHEGEWLYDITWLNYDGEYIKNVELVVESEWDINGLNSDFQKLLIARSPMKLFIFQQANEVAADRMIANFMGQIEIFNANNQYVSGDKYIFSCWLWTDHRFYHKEISL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX41</accession>
    <name>D0YX41_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Uroporphyrinogen-III C-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.107</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_001909</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="7">Porphyrin-containing compound metabolism; siroheme biosynthesis; precorrin-2 from uroporphyrinogen III: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the precorrin methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.107" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298915.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001909"/>
    <dbReference type="EnsemblBacteria" id="EEZ40877">
        <property type="protein sequence ID" value="EEZ40877"/>
        <property type="gene ID" value="VDA_001909"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0007">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1185397at2"/>
    <dbReference type="UniPathway" id="UPA00262">
        <property type="reaction ID" value="UER00211"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004851">
        <property type="term" value="F:uroporphyrin-III C-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019354">
        <property type="term" value="P:siroheme biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd11642">
        <property type="entry name" value="SUMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006366">
        <property type="entry name" value="CobA/CysG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003043">
        <property type="entry name" value="Uropor_MeTrfase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="SSF53790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01469">
        <property type="entry name" value="cobA_cysG_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00839">
        <property type="entry name" value="SUMT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00840">
        <property type="entry name" value="SUMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TP_methylase" evidence="9">
        <location>
            <begin position="22"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ40877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="275" mass="30364" checksum="539045956472E387" modified="2010-01-19" version="1">MSINPNSHNVKSIFSRKERGFVHLVGAGPGDPDLLTIRAFQIIKNATVIVYDNLVSREILQLVPNEVQLIKVGKKYNCVSTSQCEINELLVTLANQGHIVCRLKGGDPFIFGRGSEEALVLERQGISYDVVPGITAAIGCGAYSGIPLTHRGISRGVTMITAHGGDDSYQIEWDALTHLDHTLIFYMGLHKVEWITQCLINHGMDFNTPIAIVSQGTTNQHHHIIATLKTISEKLYQVSIKSPSIIIVGEVVNLAELINWYGIKKENNIHYEGVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX51</accession>
    <name>D0YX51_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted transcriptional regulator for fatty acid degradation FadQ TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001825</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298777.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001825"/>
    <dbReference type="EnsemblBacteria" id="EEZ40793">
        <property type="protein sequence ID" value="EEZ40793"/>
        <property type="gene ID" value="VDA_001825"/>
    </dbReference>
    <dbReference type="GeneID" id="57342059"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2089619at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023772">
        <property type="entry name" value="DNA-bd_HTH_TetR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041586">
        <property type="entry name" value="PsrA_TetR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17939">
        <property type="entry name" value="TetR_C_30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01081">
        <property type="entry name" value="HTH_TETR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="5"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="222" mass="25303" checksum="2E35C706DA5F2D9C" modified="2010-01-19" version="1">MTDKGNTKSRILDAAEWLFAEHGFNETSLRTITSKANVNLASVNYHFGDKKNLIRAVLGRYLECFMPLVKTEFEALLNRDEFSMVEVFRTIQTPLLQLNQLRPNGTTLFMSLIGRGYTDVQGHLRWFIVNRYQKELSLFTTAICRANPSLDPESLFWRLHFTLGASVFTMASSKALCEIADNDFASKVDIEHLLDRLIPYLAAGVSAPIEHELIHLHRRVGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXB8</accession>
    <name>D0YXB8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Replication-associated recombination protein A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001658</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298461.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001658"/>
    <dbReference type="EnsemblBacteria" id="EEZ40631">
        <property type="protein sequence ID" value="EEZ40631"/>
        <property type="gene ID" value="VDA_001658"/>
    </dbReference>
    <dbReference type="GeneID" id="57342259"/>
    <dbReference type="eggNOG" id="COG2256">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="977094at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032423">
        <property type="entry name" value="AAA_assoc_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021886">
        <property type="entry name" value="MgsA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16193">
        <property type="entry name" value="AAA_assoc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12002">
        <property type="entry name" value="MgsA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="SSF48019"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="4">
        <location>
            <begin position="48"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="447" mass="49876" checksum="23D0D48A8E3D78B1" modified="2010-01-19" version="1">MNNFSLDFSSDFRPLAARMRPRTVQEYIGQKHILGEGKPLRRALEAGHLHSMILWGPPGTGKTTLAEVAANYANAEVERVSAVTSGVKDIRAAIDKARDNKMAGRRTILFVDEVHRFNKSQQDAFLPHIEDGTVTFIGATTENPSFELNNALLSRARVYKLKSLEKEEILEVLDQALNDKERGVSDTNLNFVDDVKERLADLVCGDARMSLNYLEQLIDMAEEDSKGIKQITLPLLAEVAGEKIARFDNKGDMWYDMISAVHKSIRGSNPDGALYWFARMLQAGCDPLYVARRLLAIASEDIGNADPRAMQVAVSAWDCFTRVGAYEGERAIAQAIVYLACAAKSNAVYVAFNQAKADALNSPDYEVPVHLRNAPTKLMKELGYGAEYRYAHDEPGAYAAGECYFPPEMQHTRYYYPSNRGLETKIAEKLDYLASLDAKSPLKRYQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXC2</accession>
    <name>D0YXC2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Coenzyme A disulfide reductase</fullName>
            <ecNumber evidence="5">1.8.1.14</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001662</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="1.8.1.14" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298469.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001662"/>
    <dbReference type="EnsemblBacteria" id="EEZ40635">
        <property type="protein sequence ID" value="EEZ40635"/>
        <property type="gene ID" value="VDA_001662"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0446">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1149616at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050451">
        <property type="term" value="F:CoA-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="SSF55424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="4">
        <location>
            <begin position="2"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_dim" evidence="3">
        <location>
            <begin position="328"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="442" mass="48034" checksum="C340E827F53778EB" modified="2010-01-19" version="1">MKIIIIGGEAAGMSAAAKAKRIEPNAEIVVYEASKVISFGACGLPYFIGGEFDNAEYMAEFTPEQFATKGITVLTEHRVLSIDDKSQQLTVEHCDETFTTNYDRLMIATGAKEILPPIAGLDRQGVYSLRKMQDGLTIKQALASPTCQHVTVIGSGFIGLEVVEALINQGKDVRLIERAERLIPDAFEPEISQLLYHELEQAGVNIHLNESVEAVVGDHQVTSIKTDQDIYPTDMVICCTGVKPNTEFLHNTRLERLSNGAIIIDQQGKTSVENIWAAGDCATIWHAQLQKPVYVPLATGANKMGRLVGENLAGKSLQFKGTLATSCVKVLGLEAGRTGLSEAQAQAENIDYRSVFISDKCHTNYCHGQSPLHIKLIYQAQDKKIIGAQMIGNKGAVHRIDALAVAITLGATTDQLGMMDFAYAPPFSRTWDIMNVAGNVAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXE5</accession>
    <name>D0YXE5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative repressor protein luxO</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_001624</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298395.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001624"/>
    <dbReference type="EnsemblBacteria" id="EEZ40597">
        <property type="protein sequence ID" value="EEZ40597"/>
        <property type="gene ID" value="VDA_001624"/>
    </dbReference>
    <dbReference type="GeneID" id="57342298"/>
    <dbReference type="eggNOG" id="COG2204">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="123059at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002197">
        <property type="entry name" value="HTH_Fis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025943">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025944">
        <property type="entry name" value="Sigma_54_int_dom_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02954">
        <property type="entry name" value="HTH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00158">
        <property type="entry name" value="Sigma54_activat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00676">
        <property type="entry name" value="SIGMA54_INTERACT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00688">
        <property type="entry name" value="SIGMA54_INTERACT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50045">
        <property type="entry name" value="SIGMA54_INTERACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Response regulatory" evidence="8">
        <location>
            <begin position="9"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="7">
        <location>
            <begin position="145"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="6">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ40597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="479" mass="52786" checksum="B4C892EDC04FBFC1" modified="2010-01-19" version="1">MESKSRQKQVLMVEDTASVAALYKSYLNPLGLNVNIVGTGKEALSFIHDIVPDLILLDLRLPDMTGIEVLAAVRELHPDLAVVIMTAHGSIDVAVEAMRHGAQDFLIKPCEADRLRITVNNVLKQEHKSNAEPKSKQSGAQYQGFIGNSLAMQAVYRVIESAASSKATVFITGESGTGKEVCAEAIHAASPRHDKPFVALNCAAIPKELIESELFGHVKGAFTGASSERQGAVELADNGTLFLDELCEMDLDLQSKLLRFIQSGTYQKVGSSKTNTVDVRFVCATNRNPWVEVQEGRFREDLYYRLHVIPINLPPLRERGSDVIEIAHALLGMTSVEEGKDFTRFAPDVVEYFQKYNWPGNIRELQNVIRNIVVLHSGEVVTTEMLPPPLNQDIGANIADTVHSVSNHSLEQNTYSLADRSNESVHNNKIEPLWIVEKRAIQKAIDACDGNIPRAAGLLEVSPSTIYRKLQAWQDAASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXI0</accession>
    <name>D0YXI0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">VDA_001703</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298544.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001703"/>
    <dbReference type="EnsemblBacteria" id="EEZ40674">
        <property type="protein sequence ID" value="EEZ40674"/>
        <property type="gene ID" value="VDA_001703"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0784">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4191">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004721">
        <property type="term" value="F:phosphoprotein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Response regulatory" evidence="11">
        <location>
            <begin position="5"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="9">
        <location>
            <begin position="203"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="10">
        <location>
            <begin position="534"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="8">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ40674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="649" mass="73521" checksum="197FB7AF9AD216A7" modified="2010-01-19" version="1">MNSFVILCLDDDPTVVQQLQQDLNGFSHLFDILTAQTIAEAYQILVQVAQNNQTVAMVLCDNDLGNDSGIDFLIQLHQHPITEQARTVLLNDKAQLDDIMQAVNEGRLNYCLTKPWQSQELLPMVAKELTSYVLKHPEVDWLLYSQVLEHRRILKAHIDRQMSRFRSRFIQTTEEVNDERLAQQVSSALNQFFAQNDETKARRTYSPGHILTTEGQPNAFLWFISQGEVALYKKDEQNKQHEVVRVGAGHLVGGMSFMTGEVSFSTGITQTVTDVIKLDQQLFTQVMNSQNELLPLFTNLLLRNFNRRLQGSIQTEMKLQQTLQSLDDAYHQLIDKEKMAMLGQLVAGVAHELNNPVSAILRGSDTLKETIIKLTDSQLSLENQQRGNIILQQAMHSRPLSTSDARAKAKELQSQLGDRQLARKAVQMGLDDPELLTDWLLSQKNDLPQVMAEWDNYYQMGNFLRSINVCAQRIADLVKSLKSYARQDDESQHMANIHEGIEDTLIIFDNKLKRNTVIKNYANLPEICCQPIALQQVWTNLIANALDAIEQPGEIIITTQYSTILDNAIDIIFQDNGKGIPAELQRKIFELNYTTKREGNFGLGIGLSVCQQIVNQHQGRISVESKSGCYTKMIVTLPISLPFNQQEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXJ3</accession>
    <name>D0YXJ3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Lead cadmium zinc and mercury transporting ATPase</fullName>
            <ecNumber evidence="10">3.6.3.3</ecNumber>
            <ecNumber evidence="10">3.6.3.4</ecNumber>
            <ecNumber evidence="10">3.6.3.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_001707</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.3" evidence="10"/>
    <dbReference type="EC" id="3.6.3.4" evidence="10"/>
    <dbReference type="EC" id="3.6.3.5" evidence="10"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298550.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001707"/>
    <dbReference type="EnsemblBacteria" id="EEZ40678">
        <property type="protein sequence ID" value="EEZ40678"/>
        <property type="gene ID" value="VDA_001707"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2217">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="237367at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017969">
        <property type="entry name" value="Heavy-metal-associated_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027256">
        <property type="entry name" value="P-typ_ATPase_IB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00941">
        <property type="entry name" value="CDATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="SSF55008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01525">
        <property type="entry name" value="ATPase-IB_hvy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01047">
        <property type="entry name" value="HMA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="233"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="271"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="436"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="468"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="774"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="9">
        <location>
            <begin position="124"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="54"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="54"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="69"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="96"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ40678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="823" mass="87300" checksum="B00C80BB81D52CD0" modified="2010-01-19" version="1">MCAQCNNKKPHIHAVKPVGTTKATVQVEHASLDTCCQSSASSCCSVSNACSSESESGDDSGGDGRQSSSHIESSHHHTDHDHDHDHDHDHHDHGSQCCSTTPAMSKEQEQQLADQLAHNSHGLTLSWKVDGMDCPSCAAKLEKAITSLEPVETAKVMFATEKLIVNTKSHSGDAATIKSLIEQKSLQTGFTLLSANQKSSEVKQPFWQQHLAVLIIAGLMLISAIINQFSHSIGLAAFTLTTLVGLYPVAIKAIKLAKSGSPFSIETLMSVAAIGALYLGDTAEAAMVILLFLIGEQLEGYAASRARSGVQALMALVPEEATVILPNGEQKKVPASELKPGDIIEVAPGSRLPADGQILTSSVSFDESALTGESVPVERQLGEKVMAGCMVVDKVVRLTIISAQGENAIDRILHLIEDAEARKAPLERFLDKFSRWYTPAMIGLAALVIVVPPLFFGGVWDTWIYKGLTLLLIACPCALVISTPAAITSGLAAAARHGALIKGGAALEQLGHVEVVAFDKTGTLTEGKPVVTDAVSWDGDDDKLLRQAAAVEMGSLHPLAMAVVNLAKERSLPLSEADERQAIVGRGIQGVTEGDHFMLCAADRLPQDIQLSDNQKEQALALESQGKTLVVAVRNGHAVGLIAWRDNLRKDAIDAVRKLEKLGVRSLMLTGDNPRAAQAIASELGNMEFRASLLPEDKVTEVRKATEKAHVAMVGDGINDAPAMKTASIGIAMGGGTDVALETAEAALTHNRVAELPVMIELSRATLANIRQNITLALGLKALFLVTTLLGFTGLWVAVLADSGATALVTLNALRLLKFKSKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXJ6</accession>
    <name>D0YXJ6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Threonine efflux protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_001710</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298556.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001710"/>
    <dbReference type="EnsemblBacteria" id="EEZ40681">
        <property type="protein sequence ID" value="EEZ40681"/>
        <property type="gene ID" value="VDA_001710"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1280">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1927576at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001123">
        <property type="entry name" value="LeuE-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30086">
        <property type="entry name" value="PTHR30086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01810">
        <property type="entry name" value="LysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006324">
        <property type="entry name" value="LeuE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="48"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="117"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="151"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="193"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="217" mass="23449" checksum="58ADD84B94511332" modified="2010-01-19" version="1">MIDFAVLPVYLTAVIALLLIPGPDMLLITSSSLSYGRKVGVFASLGNATSGIILTLLASMGVSALIAMNPMALEALRILGGAYLLKMGWDCIRTQHVDSPEHLQKTKSMASTLYRRAVISNLLNPKALLFFVLFLPQFVSTHIKASSGEQMLVLGLLLNVLGLLFNLFLVSMVGSVGKSLLKSEKFRTNQHKFMGIIFFILAIWLLASQVAAPAVNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXN9</accession>
    <name>D0YXN9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Choline-glycine betaine transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_001738</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40706">
        <property type="protein sequence ID" value="EEZ40706"/>
        <property type="gene ID" value="VDA_001738"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1292">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071705">
        <property type="term" value="P:nitrogen compound transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018093">
        <property type="entry name" value="BCCT_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000060">
        <property type="entry name" value="BCCT_transptr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30047">
        <property type="entry name" value="PTHR30047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02028">
        <property type="entry name" value="BCCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00842">
        <property type="entry name" value="bcct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01303">
        <property type="entry name" value="BCCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="31"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="73"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="112"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="168"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="207"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="251"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="282"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="338"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="367"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="419"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="466"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="496"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="523" mass="56668" checksum="2919C58E876CB740" modified="2010-01-19" version="1">MRKHDKYSIENTDYTIGQDNIQKWGFDVHNAVFGISAGLIILFLIAILVSDPATANATLSGVKSAIINQFDSLFIWAGNIFVLFCVALIVSPYGRIRLGGQDAEAEHSTMSWLAMLFAAGMGIGLMFWSVAEPVAYYTGWAGTPLGVTPDTPQAVEVAMGATMYHWGLHPWAIYGVVALAMAFFAYNKGLPLSIRSVFYPLLGDRTWGWAGHIIDILAVLATLFGLATSLGLGAQQAASGMHHVFGISDGLTLQISIIVVVTLIAIYSVSQGIDSGVKLLSNINMLVAIVLLVFVILVGFGAFADTLPKTIMGYVKNFIPLSNPYDRPDEAWLHDWTVVYWAWWISWSPFVGSFIARVSKGRTVREFLIAVLIVPTVVTTVWMSAFGGQAIHQVIDHIGTLGANGLKEVPLAMFQMYDALPFGSILSIISVLLVLVFFITSSDSGSLVIDSITAGGKVDNPVPQRIFWAAIEGAIAIALLWVGGTQAIQALQAGTISTALPFTFILFLMCISLLMGFRTERFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXQ0</accession>
    <name>D0YXQ0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001742</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298609.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40710">
        <property type="protein sequence ID" value="EEZ40710"/>
        <property type="gene ID" value="VDA_001742"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="270" mass="30309" checksum="07E64AAE824127BB" modified="2010-01-19" version="1">MSYCKLPTLFFIALSALVGCNDHHQHTKINLAINYFSQAPESILAKVNILGQQERLVADWLSQNLYEARETSEYQHSHFISLYSNQSQRQGTSTSALALVDVLLLKPDSIAEHQFAIPKGKPILATTMNLAPFRHDGLNLFGIDGDKNRVFTKYYDKDLVGFISLNNSNYDPTTSVTKNDIVRLKETVHELEQNHINKVILVSQFDMKTTQAIIAKAQLTNIDVVLTQEAPKKAVLDGGTCYASFSNHFDQLDRLQLQFSQQGAITICSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXQ8</accession>
    <name>D0YXQ8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002071</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299344.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002071"/>
    <dbReference type="EnsemblBacteria" id="EEZ41039">
        <property type="protein sequence ID" value="EEZ41039"/>
        <property type="gene ID" value="VDA_002071"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="846433at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="5"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="303" mass="34490" checksum="D14798684FC23306" modified="2010-01-19" version="1">MKRALPLKSINSFIAVAQTGSMSEAANELHVSHSAISQSIKSLEIMLERPLFERIGRRVQLNDEGKRYYDKIAPAFEHIVSATEELLASKKEEHLTLNMVNSLALHWWIPRVESFQQYAPDIDIRMSNLIGCFNLDKHSVDAALVHGNRNEWLGYYCEPLLDDELVMVCSSELLAHKGMDTELLDASVIASLLQQSKPIFVVNDKRKDDWDTWCQQNGVNPPDMSKGLIFPASIQAVQATIRRLGILVTHRLFVRDDIRYGLLTEIGHNVRCDDLSFFLACNHNKAGQKSMVVLTEWLKREFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY00</accession>
    <name>D0YY00_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Molybdenum cofactor guanylyltransferase</fullName>
            <shortName evidence="4">MoCo guanylyltransferase</shortName>
            <ecNumber evidence="4">2.7.7.77</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">GTP:molybdopterin guanylyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Mo-MPT guanylyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Molybdopterin guanylyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Molybdopterin-guanine dinucleotide synthase</fullName>
            <shortName evidence="4">MGD synthase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">mobA</name>
        <name evidence="6" type="ORF">VDA_002163</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>GTP + H(+) + Mo-molybdopterin = diphosphate + Mo-molybdopterin guanine dinucleotide</text>
            <dbReference type="Rhea" id="RHEA:34243"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
            <dbReference type="ChEBI" id="CHEBI:71310"/>
            <dbReference type="EC" id="2.7.7.77"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="4">The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the MobA family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.77" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299571.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002163"/>
    <dbReference type="EnsemblBacteria" id="EEZ41131">
        <property type="protein sequence ID" value="EEZ41131"/>
        <property type="gene ID" value="VDA_002163"/>
    </dbReference>
    <dbReference type="GeneID" id="57341696"/>
    <dbReference type="eggNOG" id="COG0746">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2019898at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061603">
        <property type="term" value="F:molybdenum cofactor guanylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02503">
        <property type="entry name" value="MobA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00316">
        <property type="entry name" value="MobA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025877">
        <property type="entry name" value="MobA-like_NTP_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013482">
        <property type="entry name" value="Molybde_CF_guanTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12804">
        <property type="entry name" value="NTP_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02665">
        <property type="entry name" value="molyb_mobA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 4" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="1 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transf_3" evidence="5">
        <location>
            <begin position="10"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="12"/>
            <end position="14"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="25"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="197" mass="21896" checksum="414120EE23D0D085" modified="2010-01-19" version="1">MPMPEQTRWVILAGGRASRMGGNDKGLISLSGQPLIQHVINTLKPQTNKIIINANRNHDEYAKYAQVFGDQIQDFPGPLGGMHAALHALPDEWIGFVPCDCPQLPHDLIARMCAACDQDTDIAVAHNGEHIQPVVTLINRRILPKLETFLANGDRKIILLYRQCNMITVDFSDQADAFINLNTPEELNHFGANHESN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY31</accession>
    <name>D0YY31_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Inorganic diphosphatase</fullName>
            <ecNumber evidence="3">3.6.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Pyrophosphate phospho-hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_002194</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>diphosphate + H2O = H(+) + 2 phosphate</text>
            <dbReference type="Rhea" id="RHEA:24576"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="EC" id="3.6.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="3.6.1.1" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299625.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002194"/>
    <dbReference type="EnsemblBacteria" id="EEZ41162">
        <property type="protein sequence ID" value="EEZ41162"/>
        <property type="gene ID" value="VDA_002194"/>
    </dbReference>
    <dbReference type="GeneID" id="57341665"/>
    <dbReference type="eggNOG" id="COG1227">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="732679at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004427">
        <property type="term" value="F:inorganic diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001667">
        <property type="entry name" value="DDH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038763">
        <property type="entry name" value="DHH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004097">
        <property type="entry name" value="DHHA2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038222">
        <property type="entry name" value="DHHA2_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01368">
        <property type="entry name" value="DHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02833">
        <property type="entry name" value="DHHA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01131">
        <property type="entry name" value="DHHA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64182">
        <property type="entry name" value="SSF64182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0464">Manganese</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHHA2" evidence="9">
        <location>
            <begin position="178"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="214"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ41162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="301" mass="33037" checksum="EECB7FDDB5401E41" modified="2010-01-19" version="1">MIQVVGHKNPDSDSICSALVCTALLKARGLEATAIRQGELNRETQHILEIAGVAAPELRTSVAGEKVWLVDYSDLAQAPDDLAEAEVVGIVDHHRLGDVMTINPLEAWIWPVGCTCTVLFNLFKIEGHEITRELALLMMSAILSDTVGFASPTCTQKDKDAVAELAAIAGIEDLDAFIKALLIAKTDIAGLTAAQLVEKDLKGYPFNGRDVVVGQIELATLEQVEEMIEELEADLQRRCDEEKLAMAALMLTDITTSTTRLLYKGEWNNILDQHANDGMLMMENTLSRKKQGWPWLQEVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY55</accession>
    <name>D0YY55_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002218</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41186">
        <property type="protein sequence ID" value="EEZ41186"/>
        <property type="gene ID" value="VDA_002218"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="67" mass="6998" checksum="6CD070795B91075A" modified="2010-01-19" version="1">MVLGVTAATTTGMAAGAEYWIHSDILDKILHVLPFIGAGIAGIAVLAWLAKIVRGMQRLSANQAIPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYA2</accession>
    <name>D0YYA2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hypothetical Acyl-CoA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002265</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299758.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002265"/>
    <dbReference type="EnsemblBacteria" id="EEZ41233">
        <property type="protein sequence ID" value="EEZ41233"/>
        <property type="gene ID" value="VDA_002265"/>
    </dbReference>
    <dbReference type="GeneID" id="57341577"/>
    <dbReference type="eggNOG" id="COG4281">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1980628at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000062">
        <property type="term" value="F:fatty-acyl-CoA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022408">
        <property type="entry name" value="Acyl-CoA-binding_prot_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000582">
        <property type="entry name" value="Acyl-CoA-binding_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035984">
        <property type="entry name" value="Acyl-CoA-binding_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014352">
        <property type="entry name" value="FERM/acyl-CoA-bd_prot_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00887">
        <property type="entry name" value="ACBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00689">
        <property type="entry name" value="ACOABINDINGP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47027">
        <property type="entry name" value="SSF47027"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00880">
        <property type="entry name" value="ACB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51228">
        <property type="entry name" value="ACB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACB" evidence="1">
        <location>
            <begin position="4"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="88" mass="9853" checksum="CC7B86FACB520262" modified="2010-01-19" version="1">MSNLQAQFEQAQADVKQLTQRPTNDELLSLYALFKQATEGDVHGKRPGLFDLKGGAKYAAWEELKGMSQEDAQTQYVDKVSQLSQVYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYG9</accession>
    <name>D0YYG9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Threonine--tRNA ligase</fullName>
            <ecNumber evidence="12">6.1.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Threonyl-tRNA synthetase</fullName>
            <shortName evidence="12">ThrRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">thrS</name>
        <name evidence="15" type="ORF">VDA_002332</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + H(+) + L-threonyl-tRNA(Thr)</text>
            <dbReference type="Rhea" id="RHEA:24624"/>
            <dbReference type="Rhea" id="RHEA-COMP:9670"/>
            <dbReference type="Rhea" id="RHEA-COMP:9704"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78534"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="12">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.3" evidence="12"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299894.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002332"/>
    <dbReference type="EnsemblBacteria" id="EEZ41300">
        <property type="protein sequence ID" value="EEZ41300"/>
        <property type="gene ID" value="VDA_002332"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0441">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="900765at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004829">
        <property type="term" value="F:threonine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006435">
        <property type="term" value="P:threonyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00771">
        <property type="entry name" value="ThrRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00184">
        <property type="entry name" value="Thr_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002320">
        <property type="entry name" value="Thr-tRNA-ligase_IIa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033728">
        <property type="entry name" value="ThrRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012947">
        <property type="entry name" value="tRNA_SAD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11451">
        <property type="entry name" value="PTHR11451"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02824">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07973">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01047">
        <property type="entry name" value="TRNASYNTHTHR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00863">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="SSF55186"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="SSF81271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00418">
        <property type="entry name" value="thrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12 15" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="8 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 12 15" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10 12" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 12" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 12" id="KW-0820">tRNA-binding</keyword>
    <keyword evidence="7 12" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="TGS" evidence="14">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="13">
        <location>
            <begin position="244"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Catalytic" evidence="12">
        <location>
            <begin position="244"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="335"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="386"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="512"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEZ41300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="643" mass="73662" checksum="97CD3480A4326AD1" modified="2010-01-19" version="1">MPVITLPDGSQRQFENPVSTMDVALSIGPGLAKATIAGRVDGVRVDACDLIENDASLEIITAKDEVDGLEIVRHSCAHLLGHAIKQLYPEAKMAIGPTIDNGFYYDIDLEQSLTQEDLEVIEKRMLELAKTKYQVVKKKVSWQEARDTFESRGETYKIEILDENVARDDRPGLYHHEEYIDMCRGPHVPHMGFCQNFKLLSVAGAYWRGNSENKMLQRIYGTAFHDKKALKAHLTRLEEAAKRDHRKIGKQLDLFHMQQEAPGMVFWHHNGWTIFRELEVFVREKLNQYDYQEVKGPLMMDRVLWERSGHWDKYADAMFTTSSENREYAIKPMNCPGHVQIFNQGLKSYRDLPLRMAEFGSCHRNEPSGSLHGIMRVRGFTQDDAHIFCTESQVQQEVTSCIEMVYDTYKTFGFENIVVKLSTRPEKRVGSDAMWDKAEADLVTALESMDIPFEIQEGEGAFYGPKIEFTLHDCLDRAWQCGTVQLDFALPERLGATYVGEDNERHTPVMIHRAILGSLERFIGILIEDYAGFFPTWLAPQQAVVMNITDSQSEYVQEIVEKLKKCGIRVNADLRNEKIGFKIREHTLKRVPYMLVCGDQEVEAGEVAVRTRKGKDLGKFKIDDLVAYMQQEISSRKLNIVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYY9</accession>
    <name>D0YYY9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Succinate dehydrogenase iron-sulfur subunit</fullName>
            <ecNumber evidence="7">1.3.5.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_002502</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a quinone + succinate = a quinol + fumarate</text>
            <dbReference type="Rhea" id="RHEA:40523"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.3.5.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="7">Binds 1 [2Fe-2S] cluster.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </cofactor>
        <text evidence="7">Binds 1 [3Fe-4S] cluster.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="7">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.</text>
    </comment>
    <dbReference type="EC" id="1.3.5.1" evidence="7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300210.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002502"/>
    <dbReference type="EnsemblBacteria" id="EEZ41470">
        <property type="protein sequence ID" value="EEZ41470"/>
        <property type="gene ID" value="VDA_002502"/>
    </dbReference>
    <dbReference type="GeneID" id="57341274"/>
    <dbReference type="eggNOG" id="COG0479">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1605514at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051538">
        <property type="term" value="F:3 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008177">
        <property type="term" value="F:succinate dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004489">
        <property type="entry name" value="Succ_DH/fum_Rdtase_Fe-S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025192">
        <property type="entry name" value="Succ_DH/fum_Rdtase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13085">
        <property type="entry name" value="Fer2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00384">
        <property type="entry name" value="dhsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="6 7" id="KW-0003">3Fe-4S</keyword>
    <keyword evidence="7" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4 7" id="KW-0408">Iron</keyword>
    <keyword evidence="5 7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="8">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="9">
        <location>
            <begin position="137"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ41470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="236" mass="26379" checksum="A9F09BEE72C3854E" modified="2010-01-19" version="1">MKLNFSIYRYNPDIDDAPHMKGYTLDVPEGTDMMVLDALILLKEQDPSIAFRRSCREGVCGSDGINMNGKNGLACITPLSTLMTQSTIVIRPLPGLPVIRDLIIDMEQFYSNYAKVKPFLMNEGIPPAREHLQSPEERAHLDGLYECIMCACCSTSCPSFWWNPDKFIGPAGLLAAYRWLIDSRDTATDERLSELDDAFSVFRCHGIMNCVNVCPKGLNPTKAIGHIKSMLLKRAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ60</accession>
    <name>D0YZ60_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cytochrome c-type biogenesis protein CcmG/DsbE thiol:disulfide oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_002573</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
            <orientation evidence="1">Periplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the thioredoxin family. DsbE subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300370.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002573"/>
    <dbReference type="EnsemblBacteria" id="EEZ41541">
        <property type="protein sequence ID" value="EEZ41541"/>
        <property type="gene ID" value="VDA_002573"/>
    </dbReference>
    <dbReference type="GeneID" id="57341186"/>
    <dbReference type="eggNOG" id="COG0526">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1617952at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015036">
        <property type="term" value="F:disulfide oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03010">
        <property type="entry name" value="TlpA_like_DsbE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004799">
        <property type="entry name" value="Periplasmic_diS_OxRdtase_DsbE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013740">
        <property type="entry name" value="Redoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08534">
        <property type="entry name" value="Redoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00385">
        <property type="entry name" value="dsbE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0201">Cytochrome c-type biogenesis</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Thioredoxin" evidence="8">
        <location>
            <begin position="39"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007758"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="184" mass="20917" checksum="8CE3632174F50896" modified="2010-01-19" version="1">MNKKFLFIPLVIFLALVAMFMVQLLRNADGDDPTKLESVLVGKPVPTFKLEDIFEPGKEYEQTIFKGQPLLLNVWATWCPTCYAEHQYLNQLAKQGVKIIGLNYKDDRAKAIDWLTQLGNPYVHTLYDNTGMLGMDLGVYGAPETFLIDGNGIIRYRHVGDVNATNWNETLKPIYDKMKEEAKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZA3</accession>
    <name>D0YZA3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Flagellar hook protein FlgE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_002616</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Bacterial flagellum basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the flagella basal body rod proteins family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300499.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002616"/>
    <dbReference type="EnsemblBacteria" id="EEZ41584">
        <property type="protein sequence ID" value="EEZ41584"/>
        <property type="gene ID" value="VDA_002616"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1749">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="704242at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.98.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011491">
        <property type="entry name" value="Falgellar_hook_FlgE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037058">
        <property type="entry name" value="Falgellar_hook_FlgE_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001444">
        <property type="entry name" value="Flag_bb_rod_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019776">
        <property type="entry name" value="Flagellar_basal_body_rod_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020013">
        <property type="entry name" value="Flagellar_FlgE/F/G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010930">
        <property type="entry name" value="Flg_bb/hook_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037925">
        <property type="entry name" value="FlgE/F/G-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07559">
        <property type="entry name" value="FlaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00460">
        <property type="entry name" value="Flg_bb_rod"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06429">
        <property type="entry name" value="Flg_bbr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117143">
        <property type="entry name" value="SSF117143"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03506">
        <property type="entry name" value="FlgEFG_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00588">
        <property type="entry name" value="FLAGELLA_BB_ROD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="9" id="KW-0966">Cell projection</keyword>
    <keyword evidence="9" id="KW-0969">Cilium</keyword>
    <keyword evidence="9" id="KW-0282">Flagellum</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flg_bb_rod" evidence="6">
        <location>
            <begin position="4"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="domain" description="FlaE" evidence="8">
        <location>
            <begin position="182"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="domain" description="Flg_bbr_C" evidence="7">
        <location>
            <begin position="370"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF06429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="449" mass="48452" checksum="193829784FFE58F1" modified="2010-01-19" version="1">MSVNIALSGLGAAQKDLNTTSNNIANANTYGFKESRAEFGDVYSNSIFSNAKTSTGGGVQTSTVAQQFHEGSSLYTNNPLDLRISGAGFFAVADNKAEPANNSLTRNGAFHLNNQNELVNSEGKFLLGYEVNSDTNTVSSYEPKSMKIDDVFGKPTPSKTMDISLNLPNKETTPKNHPFNFDDKDSYSRSTSSTIYDSLGKPYKMNTYYVAKYNPADPTTANTWEVYHTVTNPSGKELPLDVDTAKLNPAFVANGAIHGTAAHKGYIMKFDTSGQQQAGSPSVINMVNFKTAGIDVGGADDSQALTMNYKEPTQYASPFEVRQFKDVDGATTGYLSKVDIDPDGNVLASYSNGKDRIVGRVAMARVSNEQGLSQLGGTLWNVTQESGDAVWGDASQGSFGAIKSGTLEQSNIDMTQELVDLITAQRNFQASSRALEVNNQLQQNILQIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZF7</accession>
    <name>D0YZF7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Flagellar motor rotation protein MotB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_002670</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MotB family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300662.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002670"/>
    <dbReference type="EnsemblBacteria" id="EEZ41638">
        <property type="protein sequence ID" value="EEZ41638"/>
        <property type="gene ID" value="VDA_002670"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1360">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1619550at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07185">
        <property type="entry name" value="OmpA_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025713">
        <property type="entry name" value="MotB_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006665">
        <property type="entry name" value="OmpA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036737">
        <property type="entry name" value="OmpA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13677">
        <property type="entry name" value="MotB_plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00691">
        <property type="entry name" value="OmpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103088">
        <property type="entry name" value="SSF103088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51123">
        <property type="entry name" value="OMPA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0966">Cell projection</keyword>
    <keyword evidence="8" id="KW-0969">Cilium</keyword>
    <keyword evidence="8" id="KW-0282">Flagellum</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="domain" description="OmpA-like" evidence="7">
        <location>
            <begin position="172"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="106"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="294"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="119"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ41638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="314" mass="34801" checksum="6C653DFE3E5B0406" modified="2010-01-19" version="1">MEIESSKKQSGAPAWMATFADLATLLMCFFVLLLSFSEMDVMKFKQIAGSMKNAFGVQNLLDINDIPKGTSVIAQEFRPGRPEPTPIEVIMQQTIDMTQRTLDFHEGESDKAGGTERSAGTLTGGQADKKNKTQQQDQDQNASDSLKQLEKVLNKAIEREIEEGNVEIENFGQQLVIRIKEQGAFPEGSAFLQPKFRPLVRQVASLVKDVPGTVRISGHTDDRPVESELYRSNWDISAQRAVSVAQEMAKVTGFDQHRMQVVGLADTAPIASNDTAEGRKRNRRVEISIMQGKPYYSDPISVDSVPPMTAEHTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZG3</accession>
    <name>D0YZG3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Thiamine-monophosphate kinase</fullName>
            <shortName evidence="2">TMP kinase</shortName>
            <shortName evidence="2">Thiamine-phosphate kinase</shortName>
            <ecNumber evidence="2">2.7.4.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">thiL</name>
        <name evidence="5" type="ORF">VDA_002676</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + thiamine phosphate = ADP + thiamine diphosphate</text>
            <dbReference type="Rhea" id="RHEA:15913"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; thiamine diphosphate biosynthesis; thiamine diphosphate from thiamine phosphate: step 1/1.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="2">Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the thiamine-monophosphate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.16" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300677.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002676"/>
    <dbReference type="EnsemblBacteria" id="EEZ41644">
        <property type="protein sequence ID" value="EEZ41644"/>
        <property type="gene ID" value="VDA_002676"/>
    </dbReference>
    <dbReference type="GeneID" id="57341055"/>
    <dbReference type="eggNOG" id="COG0611">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1016556at2"/>
    <dbReference type="UniPathway" id="UPA00060">
        <property type="reaction ID" value="UER00142"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009030">
        <property type="term" value="F:thiamine-phosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02194">
        <property type="entry name" value="ThiL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.650.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02128">
        <property type="entry name" value="TMP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010918">
        <property type="entry name" value="PurM-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036676">
        <property type="entry name" value="PurM-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016188">
        <property type="entry name" value="PurM-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036921">
        <property type="entry name" value="PurM-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006283">
        <property type="entry name" value="ThiL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30270">
        <property type="entry name" value="PTHR30270"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00586">
        <property type="entry name" value="AIRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02769">
        <property type="entry name" value="AIRS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005303">
        <property type="entry name" value="Thiam_monoph_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55326">
        <property type="entry name" value="SSF55326"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56042">
        <property type="entry name" value="SSF56042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01379">
        <property type="entry name" value="thiL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 5" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AIRS" evidence="3">
        <location>
            <begin position="29"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="AIRS_C" evidence="4">
        <location>
            <begin position="150"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="30"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>4</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="47"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="75"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="121"/>
            <end position="122"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="214"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="215"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>5</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="265"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="320"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="328" mass="34935" checksum="AB685B175BA11368" modified="2010-01-19" version="1">MARNEFELITRYFENQAVNRKDVTLSIGDDCALLEVPAGCHLAVSTDSLVAGTHFLADADPALVAHKALASNISDLAAMGATPAWVSLALTMPEPDETWLSEFCRGFFALAEYYNIELIGGDTTKGPLSLTLTVQGFIPHGQALTRRGAKAGDWIYVTGNLGDSAAGLAVILGQENGLSSSLAETLVQRHYISQPRVLAGQALRGIASAALDISDGLISDLGHILKQSQVGAEIDVTKLPLSPELLQFAGHNVEQAQKLALTSGEEYELCFTVPEHNRGALDTALAHAGVKVTCIGQLVPALGVTLKNSDVELDWQLTGWDHFAHQNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZI2</accession>
    <name>D0YZI2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted metal-dependent hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002695</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300722.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002695"/>
    <dbReference type="EnsemblBacteria" id="EEZ41663">
        <property type="protein sequence ID" value="EEZ41663"/>
        <property type="gene ID" value="VDA_002695"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2872">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="783542at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004812">
        <property type="term" value="F:aminoacyl-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="SSF55186"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="290" mass="32967" checksum="44D04198F294E848" modified="2010-01-19" version="1">MLNATKVLFTSNIWQCTAKVQLCVAHSEGTWIVTDTTPFHPVSHIWPDHPADRGFITVANQDYAVINCLVGAVELASQTLYVADAIPVRRDTEGWVFVVVHHLAQDLMLEIGQEVELSVDKAYQQALGRGHSGGHLSSLALNKVLHHDFWRKDASRKDELGHYDFHSYAQEKSEVSEDCSRDTYRLGKTLRKRGLNSADMLEQLNDIADKINQQLTQWLELESAITMRCEGQALTDSRYWCCDLKEGNVIEIPCGGTHSQSLAEYNQLWVEFEYVNDQQIVMYARSIKRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZM4</accession>
    <name>D0YZM4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phosphate regulon transcriptional regulatory protein PhoB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_002737</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300864.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002737"/>
    <dbReference type="EnsemblBacteria" id="EEZ41705">
        <property type="protein sequence ID" value="EEZ41705"/>
        <property type="gene ID" value="VDA_002737"/>
    </dbReference>
    <dbReference type="GeneID" id="57340989"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="817710at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000156">
        <property type="term" value="F:phosphorelay response regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011879">
        <property type="entry name" value="Sig_transdc_resp-reg_PhoB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02154">
        <property type="entry name" value="PhoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Response regulatory" evidence="7">
        <location>
            <begin position="4"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="8">
        <location>
            <begin position="129"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="6">
        <location>
            <begin position="129"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="5">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="229" mass="26425" checksum="FF3F58978D2798A7" modified="2010-01-19" version="1">MVRRILVVEDEAPIREMLCFVLEQKGYQPIEAEDYDSALEKICEPYPELILMDWMLPGGSGINLIKHLKRDELTRQIPVVMLTARGEEEDKVRGLEVGADDYITKPFSPKELMARLKAVMRRVSPTALDDTIDVQGLKLDPVSHRVTSNDEPLDMGPTEFKMLHFFMTHQERVYSREQLLNNIWGTNVYVEDRTVDVHIRRLRKALEASGHEKLIQTVRGAGYRFSTRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZS7</accession>
    <name>D0YZS7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">HipA protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_002790</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HipA Ser/Thr kinase family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301013.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002790"/>
    <dbReference type="EnsemblBacteria" id="EEZ41758">
        <property type="protein sequence ID" value="EEZ41758"/>
        <property type="gene ID" value="VDA_002790"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3550">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1293681at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012893">
        <property type="entry name" value="HipA-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017508">
        <property type="entry name" value="HipA_N1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13657">
        <property type="entry name" value="Couple_hipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07804">
        <property type="entry name" value="HipA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03071">
        <property type="entry name" value="couple_hipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Couple_hipA" evidence="4">
        <location>
            <begin position="6"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="HipA_C" evidence="3">
        <location>
            <begin position="149"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="433" mass="48668" checksum="03FB3179174E5D7C" modified="2010-01-19" version="1">MQKLIAYMNGELVGTLEKHKNGAHTFQYDKNWLTNAVTRPLSLSLKLQLPAITSDAVINYFDNLLPDSPQVRDRIVARYKASSKQPFDLLKEIGKDSVGAIALLPPDRPYKKEPLSYEVLDNKKLETVLSAYKSDIPLGMLEEEEDFRISVAGAQEKTALLFADEQWCIPKGNTPTTHIIKLPIGEIQQANATLDLKDSVENEYLCIELARALGVTVPNVNIIQTDNIKALAVERFDRRWTKDRASLLRLPQEDICQVFGMPSSIKYESQGGPGIAQIMELLMGSSNALEDRYNFMRFQVFQWLIGATDGHAKNFSIYIDKGGSYRLTPFYDILSAYPLLGGKGLNIRKLKLAMGLKATKGKKYEISKILPRHFLDTAKDVNFNQDTMQEIIDEMKDALPKAMLQVSATLPKGFPEHIVGSIFENTQKIVKKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZV1</accession>
    <name>D0YZV1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative deoxyribonuclease YjjV</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002814</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002814"/>
    <dbReference type="EnsemblBacteria" id="EEZ41782">
        <property type="protein sequence ID" value="EEZ41782"/>
        <property type="gene ID" value="VDA_002814"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0084">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01310">
        <property type="entry name" value="TatD_DNAse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018228">
        <property type="entry name" value="DNase_TatD-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001130">
        <property type="entry name" value="TatD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01026">
        <property type="entry name" value="TatD_DNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005902">
        <property type="entry name" value="DNase_TatD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01137">
        <property type="entry name" value="TATD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01091">
        <property type="entry name" value="TATD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="305" mass="34163" checksum="2A6EED31ED960FF7" modified="2010-01-19" version="1">MLWWKKNSKKSAIALPHNFNRIWKQQRRKSAIERTKLIGFTMLIDSHCHFDFEPFIQAPNSYLEQAKQAGVGAIVIPSVGLNNWSLVAKLCSEYPELYYGLGLHPFFNHQHDLAALELLKVHIETDINIGRKCVAIGECGLDFAIEGGQTLAVKQQQIALLEGQLQLANEFNLPVILHCRKAFPELIQLIKHNQLKAGGVFHAFSGSVQQAQQIIELGIKIGVGGTITYPRAKKTRHTISQLPLNVLMLETDAPDMPVCGYQGEPNRPDRLVDIVDVLTALRGESRAEIERITSLTSTELFKLKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZW3</accession>
    <name>D0YZW3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ubiquinone biosynthesis protein UbiU</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ubiU</name>
        <name evidence="2" type="ORF">VDA_002826</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiV, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Forms an heterodimer with UbiV.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase U32 family. UbiU subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301121.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002826"/>
    <dbReference type="EnsemblBacteria" id="EEZ41794">
        <property type="protein sequence ID" value="EEZ41794"/>
        <property type="gene ID" value="VDA_002826"/>
    </dbReference>
    <dbReference type="GeneID" id="57340892"/>
    <dbReference type="eggNOG" id="COG0826">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1264653at2"/>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02232">
        <property type="entry name" value="UbiU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001539">
        <property type="entry name" value="Peptidase_U32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043692">
        <property type="entry name" value="UbiU"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01136">
        <property type="entry name" value="Peptidase_U32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01276">
        <property type="entry name" value="PEPTIDASE_U32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="335" mass="37324" checksum="1CBBB0DC43D19595" modified="2010-01-19" version="1">MELLCPAGNLPALKTAVDNGADAVYIGFKDDTNARHFAGLNFTGRKLDKAVEYIRDHNRKLHVALNTFAHPDGFSRWTKAVDNAAAMGVDALIVADIAVLEYAATRYPDLELHLSVQASATNTAAIDFYKQNFNVKRVVLPRVLSIHQVKQLARNTDVELEVFAFGSLCIMSEGRCYLSSYMTGESPNTVGACSPAKYVRWQETNQGLESRLNEVLIDRYSAGENAGYPTLCKGRFDVNLDGNDKRYHALEEPTSLNTLEILPELFKANIASVKIEGRQRSPAYVEQVTRTWRAAIDRYLANPEGYSVDPAWNQCLGNVSEGRQTTLGAYHRKWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z023</accession>
    <name>D0Z023_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Hypothetical sensory box/GGDEF family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_002886</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301273.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002886"/>
    <dbReference type="EnsemblBacteria" id="EEZ41854">
        <property type="protein sequence ID" value="EEZ41854"/>
        <property type="gene ID" value="VDA_002886"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2202">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3706">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13188">
        <property type="entry name" value="PAS_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="3">
        <location>
            <begin position="236"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="2">
        <location>
            <begin position="303"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="3">
        <location>
            <begin position="376"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="4">
        <location>
            <begin position="467"/>
            <end position="603"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="603" mass="68701" checksum="5A918DA5EDE3D15A" modified="2010-01-19" version="1">MGRYLLLLTALVSLVLATMSFLLTDETMAEFATLIVVFCIVFGGVFVLLLIYSIDSLSLEKTHQILAKMPFPVALVRLKDGQLLYCNKACRELLSIRKIGDSYLYPEYISSATVCDFLQTFHGQNSFQQWSESVPMPGNKSLSLDITGKRIRYHWYPTWMLFISKTPQNNSSENQLAQEQLMFQSVLNSLSELVYFQDPQGRIMGSNKAFDRFWQGRIEEGVLDYQQDHEHSLGTNSIHWWTTNPEGSSRLLETNQTSLINAKGDVMGTLNISHDVTEWHEMQESLRTEIERREETEQTLAQQNNLLDTIINSSTDPIGLVNQYWVYIGCNELFAQSLGYTKETLLGKSAEEVISSDKWEMFRQSDREVMELGRSTKTEDCVLKNDGTLVWYEVQKSPFIDPTDGARGMLIIARDVTERKKAEQQLADAIMELQALSFIDGLTRIANRRSFDDSLHRMWHSHIRLQQPLTLIFCDIDYFKAFNDSYGHQIGDTVLREVAAVLSSVIQRETDEVARYGGEEFAILLPTTDSKGGEYVAKKLQKALALRAQEVPFCDIPTTLTLSIGITTVIPQPNEGFQHFLEQADKALYQAKAAGRNCYRHFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z037</accession>
    <name>D0Z037_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">H(+)/Cl(-) exchange transporter ClcA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_002900</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301302.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002900"/>
    <dbReference type="EnsemblBacteria" id="EEZ41868">
        <property type="protein sequence ID" value="EEZ41868"/>
        <property type="gene ID" value="VDA_002900"/>
    </dbReference>
    <dbReference type="GeneID" id="57340808"/>
    <dbReference type="eggNOG" id="COG0038">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1560952at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005247">
        <property type="term" value="F:voltage-gated chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014743">
        <property type="entry name" value="Cl-channel_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001807">
        <property type="entry name" value="Cl-channel_volt-gated"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00654">
        <property type="entry name" value="Voltage_CLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00762">
        <property type="entry name" value="CLCHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81340">
        <property type="entry name" value="SSF81340"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="30"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="121"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="173"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="210"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="249"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="288"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="326"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="353"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="384"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="416"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="466" mass="50103" checksum="D4901866B6DF853D" modified="2010-01-19" version="1">MSDSTQGITPERLQPSGLVRRFLNRDKTPVSVLLLSALVGLLAGLIGTLFEMGVTWVSEQRTEWLRHEISSALPLWLSAFIVSAVLAVIGYYLVIRFAPEAGGSGIPEIEGAMDELRPVRWWRVIPVKFFGGLGALGSGMVLGREGPTVQMGGNIGRMVSDIFRLKDKEGRHALLAAGAAGGLAAAFNAPMAGIMFVVEEMRPQFRYSLISVKCVMISAIMADIVFRAIKGQSAVITMPQYDAPTIHALWLFLVLGLVFGVFGVIFNRLITLAQDMFAHLHHNNFPRFLLTGAMLGGSFGLLLLYLPELTGGGISIIPNATNGDYGIGMLLMLFLARMVTTLLCFGSGAPGGIFAPMLALGTLFGTFFGTIAQSYYPELGLNPGMFAIAGMGALFAATVRAPITGILLVIEMTHNYDLILPLIITSLGATLVAQMLGGQPIYSQLLHRTIKKEKLRQDPASDTVNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z055</accession>
    <name>D0Z055_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Lipopolysaccharide export system permease protein LptF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">VDA_002918</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell inner membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the LptF/LptG family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301349.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002918"/>
    <dbReference type="EnsemblBacteria" id="EEZ41886">
        <property type="protein sequence ID" value="EEZ41886"/>
        <property type="gene ID" value="VDA_002918"/>
    </dbReference>
    <dbReference type="GeneID" id="57340780"/>
    <dbReference type="eggNOG" id="COG0795">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1258802at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030922">
        <property type="entry name" value="LptF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005495">
        <property type="entry name" value="LptG/LptF_permease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33529">
        <property type="entry name" value="PTHR33529"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03739">
        <property type="entry name" value="LptF_LptG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04407">
        <property type="entry name" value="LptF_YjgP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="52"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="97"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="272"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="298"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="330"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00014213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00026081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEZ41886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="366" mass="40676" checksum="084C41BBA09820A9" modified="2010-01-19" version="1">MIIVRYLTRETLKSQFAVLFVLFLVFISQKFIRILADATDGSIPSDLITTLMGLYMPSMALLMLPLSLYIGILLTFGRLYAESEITVMNATGMGNKFLLRAALSLALITGALATFNALWLSPWAAEKEAQVMESVKADSGLDLLVKGQFQAAPNGQGVVFVNDITDKGKTLKHVFVAQLKGKDSIRPSVLVADHGYVSEHKDGRQILDLKDGTRYEGIPTRLDYSITDFEGYQAVIGQRKVKEERRDWDAMPTLELMQRAEPEAQAEFQWRMSLILCIPLLTMVVVPLSAVNPRQGRFAKLVPAVLIYLAYFLAISAGKSALEDGTLPPMIGLWSINLVILLIGVALNCWDTLPVRKLRDKVRRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z087</accession>
    <name>D0Z087_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Glycerol-3-phosphate acyltransferase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Acyl-PO4 G3P acyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Acyl-phosphate--glycerol-3-phosphate acyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">G3P acyltransferase</fullName>
            <shortName evidence="10">GPAT</shortName>
            <ecNumber evidence="10">2.3.1.275</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Lysophosphatidic acid synthase</fullName>
            <shortName evidence="10">LPA synthase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">plsY</name>
        <name evidence="11" type="ORF">VDA_002950</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>an acyl phosphate + sn-glycerol 3-phosphate = a 1-acyl-sn-glycero-3-phosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:34075"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:57970"/>
            <dbReference type="ChEBI" id="CHEBI:59918"/>
            <dbReference type="EC" id="2.3.1.275"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="10">Lipid metabolism; phospholipid metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Probably interacts with PlsX.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the PlsY family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.275" evidence="10"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301408.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002950"/>
    <dbReference type="EnsemblBacteria" id="EEZ41918">
        <property type="protein sequence ID" value="EEZ41918"/>
        <property type="gene ID" value="VDA_002950"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0344">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1691856at2"/>
    <dbReference type="UniPathway" id="UPA00085"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043772">
        <property type="term" value="F:acyl-phosphate glycerol-3-phosphate acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01043">
        <property type="entry name" value="PlsY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003811">
        <property type="entry name" value="G3P_acylTferase_PlsY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30309">
        <property type="entry name" value="PTHR30309"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02660">
        <property type="entry name" value="G3P_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01207">
        <property type="entry name" value="G3P_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00023">
        <property type="entry name" value="TIGR00023"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2 10" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6 10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 10" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="9 10" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="108"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ41918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="205" mass="22336" checksum="E4FADCD51D179E9B" modified="2010-01-19" version="1">MTPLALVIIIAAYLLGSISSAVLICRLYRLPDPRDCGSGNPGATNVLRLGGKTAASLVLVCDILKGMIPVWLSYFLGLNPFLLGIIAISACLGHIYPIFFHFRGGKGVATALGALAPIGWDLSGMLIATWLVVVIITGYSSLGSLITALIAPLFTWWVKPEYTMPVAMLSCLIIFRHHDNIRRLIDGQESKIWDKFRRKNKQNAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z098</accession>
    <name>D0Z098_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002961</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002961"/>
    <dbReference type="EnsemblBacteria" id="EEZ41929">
        <property type="protein sequence ID" value="EEZ41929"/>
        <property type="gene ID" value="VDA_002961"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="289" mass="32204" checksum="107097E08E1F3B43" modified="2010-01-19" version="1">MFDAVMQEQNITRAAHNLGMSQPAVSNAVARLKVMFNDELFIRHGRGIQPTQRAKQLFGPMRQALQLVKNELPSSIFAPETSSRTFKLAIGSPSDMRFAPRILRNIAQLAPNVTLQLDAELCDGLNQKMHYQEVDFVIDYARFEEPGFCSTELFRDELVVVAAKHHPRIGAQISESEFVSEAHAVLKSLPNSGNFADHIYNAQAGIVEAYQGASLSNILYVVAQSELVTVAPRWLVETTASNLGLKVLPLPFANNIACGYLSWHESSQKDKGHLWMRDQLLQICGDNRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0D0</accession>
    <name>D0Z0D0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Inorganic diphosphatase</fullName>
            <ecNumber evidence="2">3.6.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_002993</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="3.6.1.1" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002993"/>
    <dbReference type="EnsemblBacteria" id="EEZ41961">
        <property type="protein sequence ID" value="EEZ41961"/>
        <property type="gene ID" value="VDA_002993"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0221">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004427">
        <property type="term" value="F:inorganic diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006796">
        <property type="term" value="P:phosphate-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008162">
        <property type="entry name" value="Pyrophosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036649">
        <property type="entry name" value="Pyrophosphatase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10286">
        <property type="entry name" value="PTHR10286"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00719">
        <property type="entry name" value="Pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50324">
        <property type="entry name" value="SSF50324"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="81" mass="9201" checksum="4FD5CBD5A16A68FE" modified="2010-01-19" version="1">MTDESGEDAKVIAVPHHKVSKEYEHIQDIGDLPALLKAQITQFFERYKELEVGKWVKVDGWADATAAKAEIETSFQRAEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0E5</accession>
    <name>D0Z0E5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003009</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003009"/>
    <dbReference type="EnsemblBacteria" id="EEZ41976">
        <property type="protein sequence ID" value="EEZ41976"/>
        <property type="gene ID" value="VDA_003009"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3671">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="79" mass="9137" checksum="7018CDF6B0D24BF8" modified="2010-01-19" version="1">MAYVNKGDAPQWLQDHFRFQIRTFWIGLLLLFVGGILSSVFVGFFIVIFAYVWYIVRCVKGMKSLSQGQAPANVETWLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0F3</accession>
    <name>D0Z0F3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cold shock protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_003017</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301575.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003017"/>
    <dbReference type="EnsemblBacteria" id="EEZ41984">
        <property type="protein sequence ID" value="EEZ41984"/>
        <property type="gene ID" value="VDA_003017"/>
    </dbReference>
    <dbReference type="GeneID" id="57340531"/>
    <dbReference type="eggNOG" id="COG1278">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2034748at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04458">
        <property type="entry name" value="CSP_CDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012156">
        <property type="entry name" value="Cold_shock_CspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011129">
        <property type="entry name" value="CSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019844">
        <property type="entry name" value="CSD_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002059">
        <property type="entry name" value="CSP_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00313">
        <property type="entry name" value="CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002599">
        <property type="entry name" value="Cold_shock_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00050">
        <property type="entry name" value="COLDSHOCK"/>
    </dbReference>
    <dbReference type="SMART" id="SM00357">
        <property type="entry name" value="CSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00352">
        <property type="entry name" value="CSD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51857">
        <property type="entry name" value="CSD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CSD" evidence="3">
        <location>
            <begin position="3"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="68" mass="7435" checksum="530960506BB50FB9" modified="2010-01-19" version="1">MSKLTGTVKWFNDEKGFGFISGVDGKDVFVHYSAIQSQGRRTLREGQSVEFIVTDGQKGPQASEVVAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0M0</accession>
    <name>D0Z0M0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DNA-binding protein HU-alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_003084</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the bacterial histone-like protein family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301812.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003084"/>
    <dbReference type="EnsemblBacteria" id="EEZ42051">
        <property type="protein sequence ID" value="EEZ42051"/>
        <property type="gene ID" value="VDA_003084"/>
    </dbReference>
    <dbReference type="GeneID" id="57340438"/>
    <dbReference type="eggNOG" id="COG0776">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1847472at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000119">
        <property type="entry name" value="Hist_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020816">
        <property type="entry name" value="Histone-like_DNA-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010992">
        <property type="entry name" value="IHF-like_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33175">
        <property type="entry name" value="PTHR33175"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00216">
        <property type="entry name" value="Bac_DNA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01727">
        <property type="entry name" value="DNABINDINGHU"/>
    </dbReference>
    <dbReference type="SMART" id="SM00411">
        <property type="entry name" value="BHL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47729">
        <property type="entry name" value="SSF47729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00045">
        <property type="entry name" value="HISTONE_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ42051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="90" mass="9445" checksum="5C5D564DBDF4E645" modified="2010-01-19" version="1">MNKTQLIDLIAEKADLSKAQAKAALEATLDGITDALKEGDQVQLIGFGTFKVNHRAARTGRNPQTGAEIQIAAANVPAFVAGKALKDSVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0Q2</accession>
    <name>D0Z0Q2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Type II secretion system protein K</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">VDA_003116</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 11">Cell inner membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the GSP K family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301907.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003116"/>
    <dbReference type="EnsemblBacteria" id="EEZ42083">
        <property type="protein sequence ID" value="EEZ42083"/>
        <property type="gene ID" value="VDA_003116"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3156">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1516369at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.40.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005628">
        <property type="entry name" value="GspK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038072">
        <property type="entry name" value="GspK_central_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38831">
        <property type="entry name" value="PTHR38831"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03934">
        <property type="entry name" value="T2SSK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002786">
        <property type="entry name" value="XcpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158544">
        <property type="entry name" value="SSF158544"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5 11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 11" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR002786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ42083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="334" mass="37062" checksum="4C9A6CC86941ABDC" modified="2010-01-19" version="1">MKKQQGVALIVVLLLVALMSLIASQMTERLQKNFYRVESQILHQQTYWYGFGIEALAKVAIEQSLKDSDTATLNQPWATKDRTYPLDNGDVTGTIIDRQACFNLNALAKVKSTTDGKKPYLVGVLQTLLEDSGVESYATETIADSSWEFVDSDDAVQSATGAEDSTYAGLSPAYLPPDSLLANVTEFRAVNGVTAKIYNEVSPLLCALPTTEFKLNVNTLDKRDAPLLAAMFAPNLSVSDAEKLIADRPYNGWDKVEDFLAESVIKSVSQDTVKKAKAHLDVTSHYFQLDAEINVDRMHMRLVSLLKRDDKNKVTVVRRQYGGIRERISDDKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0T9</accession>
    <name>D0Z0T9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">Tyrosine recombinase XerC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">xerC</name>
        <name evidence="15" type="ORF">VDA_003153</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the 'phage' integrase family. XerC subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302019.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003153"/>
    <dbReference type="EnsemblBacteria" id="EEZ42120">
        <property type="protein sequence ID" value="EEZ42120"/>
        <property type="gene ID" value="VDA_003153"/>
    </dbReference>
    <dbReference type="GeneID" id="57340616"/>
    <dbReference type="eggNOG" id="COG4973">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="745068at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009037">
        <property type="term" value="F:tyrosine-based site-specific recombinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01808">
        <property type="entry name" value="Recomb_XerC_XerD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044068">
        <property type="entry name" value="CB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004107">
        <property type="entry name" value="Integrase_SAM-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011931">
        <property type="entry name" value="Recomb_XerC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023009">
        <property type="entry name" value="Tyrosine_recombinase_XerC/XerD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02899">
        <property type="entry name" value="Phage_int_SAM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02224">
        <property type="entry name" value="recomb_XerC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51900">
        <property type="entry name" value="CB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5 11" id="KW-0132">Cell division</keyword>
    <keyword evidence="6 11" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="4 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 11" id="KW-0229">DNA integration</keyword>
    <keyword evidence="9 11" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="8 11 12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core-binding (CB)" evidence="14">
        <location>
            <begin position="8"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="Tyr recombinase" evidence="13">
        <location>
            <begin position="115"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="154"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="178"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="247"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="250"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="273"/>
        </location>
    </feature>
    <feature type="active site" description="O-(3'-phospho-DNA)-tyrosine intermediate" evidence="11">
        <location>
            <position position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEZ42120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="306" mass="34718" checksum="516CC7DF938AF13F" modified="2010-01-19" version="1">MTNPVIPTSLSRPLERFYEYLRSERELSLHTQQNYKRQLSTIAEQLVEMQVTSWQQLDAGWVRQIASKGMRSGLKASSLGMRLSALRSFLDFLVFQGDLKANPAKGVSAPKKARPLPKNLDVDEMDQLLSVEGDDPLSIRDRAMMELMYGAGLRLSELVGLNLKDIQLTKGDLRVIGKGDKERIVPFSGLAKEWVGNWLKVRATLAHSDEPALFVSKRGMRISNRNVQKRMEEWGQKQAVSSHINPHKLRHSFATHMLESSGDLRAVQELLGHANLSTTQIYTHLDFQHLAKVYDEAHPRAKRGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0U0</accession>
    <name>D0Z0U0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003154</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302022.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003154"/>
    <dbReference type="EnsemblBacteria" id="EEZ42121">
        <property type="protein sequence ID" value="EEZ42121"/>
        <property type="gene ID" value="VDA_003154"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3159">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1264777at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007435">
        <property type="entry name" value="DUF484"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38765">
        <property type="entry name" value="PTHR38765"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04340">
        <property type="entry name" value="DUF484"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="59"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="240" mass="27235" checksum="71619411CA7F91A4" modified="2010-01-19" version="1">MNASSSLAEQASCDELSAEQVASYLRKEPDFFARHPELLSQIRVHHDERGAVSLVDIQLEKLRGQVTQLQDQLEQLTDQAKRNDQLFQQFSSLQAKLMQARCLQQVMPLMEQFAQQYQLNISIRLLAEPEAAKPLLKEINSDVAWLLRESFTQFQRSFMPQQNIYLGRLRHGQAALFFSQPPDLGSFALLPLKQHQTLGVLGFSSTEGGHFHPAMDTLFLQQLAIVMSSQLALWLDEAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0W4</accession>
    <name>D0Z0W4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Thioredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_003178</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the thioredoxin family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302085.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003178"/>
    <dbReference type="EnsemblBacteria" id="EEZ42145">
        <property type="protein sequence ID" value="EEZ42145"/>
        <property type="gene ID" value="VDA_003178"/>
    </dbReference>
    <dbReference type="GeneID" id="57340588"/>
    <dbReference type="eggNOG" id="COG3118">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1630944at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005746">
        <property type="entry name" value="Thioredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000077">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01068">
        <property type="entry name" value="thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 7" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Thioredoxin" evidence="8">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="7">
        <location>
            <begin position="33"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000077-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ42145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="108" mass="11596" checksum="09DBF37124793D2F" modified="2010-01-19" version="1">MSDKIVQLTDASFDSDVVNAAGPVLVDFWAEWCGPCKMIAPILDEIAEEYEGKLTIGKLNIDQNAGTPPKFGIRGIPTLLLFKDGSVAATKVGALSKTQLKEFLDANL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z101</accession>
    <name>D0Z101_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative ComM-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_003215</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003215"/>
    <dbReference type="EnsemblBacteria" id="EEZ42182">
        <property type="protein sequence ID" value="EEZ42182"/>
        <property type="gene ID" value="VDA_003215"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0606">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045006">
        <property type="entry name" value="CHLI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004482">
        <property type="entry name" value="Mg_chelat-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025158">
        <property type="entry name" value="Mg_chelat-rel_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000523">
        <property type="entry name" value="Mg_chelatse_chII-like_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32039">
        <property type="entry name" value="PTHR32039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32039:SF7">
        <property type="entry name" value="PTHR32039:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01078">
        <property type="entry name" value="Mg_chelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13335">
        <property type="entry name" value="Mg_chelatase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mg_chelatase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="Mg_chelatase_C" evidence="2">
        <location>
            <begin position="98"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ42182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="204" mass="22647" checksum="C0982941BAAC09C5" modified="2010-01-19" version="1">MPEFERKVLDSLREPLESGEIVISRATSKATFPANFQLIGALNPSPTGFYEGAQTRTNPQVILRYLSKLSGPLLDRFDMSIEIPALPKGTLAQGGERGESTPVIKARVNQARTLMDQRAGKVNARLSTRELDKHCALAREDAEFLENALHQLGLSIRAYHRIIKVARTIADLSNCEQIERAHLAEALGYRAMDRLLKQLTAQAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z124</accession>
    <name>D0Z124_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chromosome (Plasmid) partitioning protein ParA/sporulation initiation inhibitor protein soj</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003238</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302255.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003238"/>
    <dbReference type="EnsemblBacteria" id="EEZ42205">
        <property type="protein sequence ID" value="EEZ42205"/>
        <property type="gene ID" value="VDA_003238"/>
    </dbReference>
    <dbReference type="GeneID" id="57340354"/>
    <dbReference type="eggNOG" id="COG1192">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="729012at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025669">
        <property type="entry name" value="AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13614">
        <property type="entry name" value="AAA_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_31" evidence="1">
        <location>
            <begin position="3"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="265" mass="28949" checksum="319D09A01B826594" modified="2010-01-19" version="1">MGRIIAVANQKGGVGKTTTCVNLAASLAATQRKVLVIDLDPQGNATMASGVDKYQVEATAYDLLVEQTPFEQVAITETTGGYHLIAANGDVTAAEIKLMEVFAREVRLRNALATVRDNYDFIFIDCPPALNLLTINAMTAADSVLVPMQCEYFALEGLTALMDTISKLTAVVNADLKIEGLLRTMFDPRNRLANEVSDQLKKHFGDKVYRTVIPRNVRLAEAPSHGRPAMYYDKYSSGAKAYLALAGEMIRREEQQLSQAETVNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1G0</accession>
    <name>D0Z1G0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">ATP-dependent 6-phosphofructokinase</fullName>
            <shortName evidence="17">ATP-PFK</shortName>
            <shortName evidence="17">Phosphofructokinase</shortName>
            <ecNumber evidence="17">2.7.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="17">Phosphohexokinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="primary">pfkA</name>
        <name evidence="19" type="ORF">VDA_003374</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 17">Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.</text>
    </comment>
    <comment type="function">
        <text evidence="5">Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 17">
            <text>ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6-bisphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16109"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>beta-D-fructose 6-phosphate + diphosphate = beta-D-fructose 1,6-bisphosphate + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13613"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="EC" id="2.7.1.90"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 17">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="17">Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7 17">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 3/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="17">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6 17">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="17">Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.11" evidence="17"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302595.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003374"/>
    <dbReference type="EnsemblBacteria" id="EEZ42341">
        <property type="protein sequence ID" value="EEZ42341"/>
        <property type="gene ID" value="VDA_003374"/>
    </dbReference>
    <dbReference type="GeneID" id="57340176"/>
    <dbReference type="eggNOG" id="COG0205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1421302at2"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00182"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003872">
        <property type="term" value="F:6-phosphofructokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047334">
        <property type="term" value="F:diphosphate-fructose-6-phosphate 1-phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006002">
        <property type="term" value="P:fructose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00763">
        <property type="entry name" value="Bacterial_PFK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00339">
        <property type="entry name" value="Phosphofructokinase_I_B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022953">
        <property type="entry name" value="ATP_PFK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012003">
        <property type="entry name" value="ATP_PFK_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012828">
        <property type="entry name" value="PFKA_ATP_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015912">
        <property type="entry name" value="Phosphofructokinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000023">
        <property type="entry name" value="Phosphofructokinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035966">
        <property type="entry name" value="PKF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00365">
        <property type="entry name" value="PFK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000532">
        <property type="entry name" value="ATP_PFK_prok"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00476">
        <property type="entry name" value="PHFRCTKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53784">
        <property type="entry name" value="SSF53784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02482">
        <property type="entry name" value="PFKA_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00433">
        <property type="entry name" value="PHOSPHOFRUCTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 17" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="14 17" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 17" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="16 17" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="13 17 19" id="KW-0418">Kinase</keyword>
    <keyword evidence="15 17" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11 17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 17" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 17 19" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PFK" evidence="18">
        <location>
            <begin position="4"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="ADP binding; allosteric activator; shared with dimeric partner" evidence="17">
        <location>
            <begin position="22"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="17">
        <location>
            <begin position="126"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="17">
        <location>
            <begin position="170"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="ADP binding; allosteric activator" evidence="17">
        <location>
            <begin position="186"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="ADP binding; allosteric activator" evidence="17">
        <location>
            <begin position="214"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="17">
        <location>
            <begin position="250"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="17">
        <location>
            <position position="128"/>
        </location>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="12"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <begin position="73"/>
            <end position="74"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <begin position="103"/>
            <end position="106"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>ADP</name>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <note>allosteric activator</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>ADP</name>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <note>allosteric activator</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="223"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="244"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00002659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00003138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00004679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF00365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EEZ42341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="320" mass="34688" checksum="5172673B48ACE0C4" modified="2010-01-19" version="1">MIKKIGVLTSGGDAPGMNAAVRGVVRAALTEGLEVFGVFDGYQGLHQNKIKKLDRQSVSDVINKGGTFLGSARFPEFKDESVRAQAIENLKLHGIDALVVIGGDGSYMGAKKLTEMGYPCIGLPGTIDNDVAGTDYTIGYMTAMNTVIDAIDRLRDTSSSHQRISIVEVMGRHCGDLTLMSAIAGGCEYIITPETGLNKDKLLERVKEGIDKGKKHAIIAITELMTDVNELAKFIEDETGRETRATVLGHIQRGGQPTAFDRILASRMGAYAVDLLLQGEGGRCVGIQHEEMVHHDIIDAIENMKRPVRKDLYALADKLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1G5</accession>
    <name>D0Z1G5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fructose-1,6-bisphosphatase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_003379</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>beta-D-fructose 1,6-bisphosphate + H2O = beta-D-fructose 6-phosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:11064"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="EC" id="3.1.3.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the FBPase class 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302606.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003379"/>
    <dbReference type="EnsemblBacteria" id="EEZ42346">
        <property type="protein sequence ID" value="EEZ42346"/>
        <property type="gene ID" value="VDA_003379"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1494">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="879338at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042132">
        <property type="term" value="F:fructose 1,6-bisphosphate 1-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006071">
        <property type="term" value="P:glycerol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01516">
        <property type="entry name" value="FBPase_glpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004464">
        <property type="entry name" value="FBPase_class-2/SBPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30447">
        <property type="entry name" value="PTHR30447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03320">
        <property type="entry name" value="FBPase_glpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004532">
        <property type="entry name" value="GlpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00330">
        <property type="entry name" value="glpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0464">Manganese</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="87"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="163"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="185"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR004532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR004532-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR004532-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ42346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="335" mass="36152" checksum="09D3C15F9E75584E" modified="2010-01-19" version="1">MKRDLAMAFSRVTEGAALAGYKWLGRGDKNAADNAAVEVMRTLLNQTEIDGEIVIGEGEIDEAPMLYIGEKVGTGGDAVDIAVDPIEGTRMTAMGQNNALAVLAATEKGAFLKAPDMYMEKLVVGPAAKGVIDLDAPLADNLEKIATALNKSLHELVVITLAKPRHDEVIAQMQTMGVRVFAVPDGDVAASILTCMPDSEVDVMYCIGGAPEGVVSAAAIRALGGDMHGRLLPRHQVKGDCEENRRLGEDEIRRCHEMGIEPNTLLRMEDMAKSDNVIFAGTGITKGDLLEGIHRQGDIATTETLLIRGKCRTIRRIKSTHYLERKDDAIKQHIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1K1</accession>
    <name>D0Z1K1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Tryptophan--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Tryptophanyl-tRNA synthetase</fullName>
            <shortName evidence="8">TrpRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">trpS</name>
        <name evidence="10" type="ORF">VDA_003415</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the attachment of tryptophan to tRNA(Trp).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-tryptophan + tRNA(Trp) = AMP + diphosphate + H(+) + L-tryptophanyl-tRNA(Trp)</text>
            <dbReference type="Rhea" id="RHEA:24080"/>
            <dbReference type="Rhea" id="RHEA-COMP:9671"/>
            <dbReference type="Rhea" id="RHEA-COMP:9705"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78535"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8 9">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.2" evidence="8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302669.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003415"/>
    <dbReference type="EnsemblBacteria" id="EEZ42382">
        <property type="protein sequence ID" value="EEZ42382"/>
        <property type="gene ID" value="VDA_003415"/>
    </dbReference>
    <dbReference type="GeneID" id="57340134"/>
    <dbReference type="eggNOG" id="COG0180">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="951354at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004830">
        <property type="term" value="F:tryptophan-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006436">
        <property type="term" value="P:tryptophanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00806">
        <property type="entry name" value="TrpRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00140_B">
        <property type="entry name" value="Trp_tRNA_synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002306">
        <property type="entry name" value="Trp-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024109">
        <property type="entry name" value="Trp-tRNA-ligase_bac-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01039">
        <property type="entry name" value="TRNASYNTHTRP"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00233">
        <property type="entry name" value="trpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="short sequence motif" description="'HIGH' region" evidence="8">
        <location>
            <begin position="12"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="8">
        <location>
            <begin position="199"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="11"/>
            <end position="13"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="19"/>
            <end position="20"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>L-tryptophan</name>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="147"/>
            <end position="149"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="199"/>
            <end position="203"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ42382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="340" mass="37651" checksum="2203B9667D74FDD1" modified="2010-01-19" version="1">MSKPIVLSGVQPSGELSIGNYLGALRQWEQMQDDYDCQYCVVDLHAITVRQDPKALHEATLDALAICLAVGVDPQKSTLFVQSHVPEHAQLGWLLNCYTQMGELSRMTQFKDKSARHANDVNVGLFDYPVLMAADILLYGAHQVPVGSDQKQHLELARDIATRFNNIYGSEESPIFQIPEPYIPTVGARVMSLQDATKKMSKSDDNRKNVITLLEEPKSIIKKINKAQTDAETPPRIAFDIENKAGISNLMGLYSAATGKTFAEIEAQYAGVEMYGPFKKDVGEALVAMLEPVQAEYHRIRSDRAYLDSVMKQGAEKASARAAEVLKKAYQAVGFVTRPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1M1</accession>
    <name>D0Z1M1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">30S ribosomal protein S7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rpsG</name>
        <name evidence="10" type="ORF">VDA_003435</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the universal ribosomal protein uS7 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302777.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003435"/>
    <dbReference type="EnsemblBacteria" id="EEZ42402">
        <property type="protein sequence ID" value="EEZ42402"/>
        <property type="gene ID" value="VDA_003435"/>
    </dbReference>
    <dbReference type="GeneID" id="57340108"/>
    <dbReference type="eggNOG" id="COG0049">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1540940at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.455.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00480_B">
        <property type="entry name" value="Ribosomal_S7_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000235">
        <property type="entry name" value="Ribosomal_S5/S7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005717">
        <property type="entry name" value="Ribosomal_S7_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020606">
        <property type="entry name" value="Ribosomal_S7_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023798">
        <property type="entry name" value="Ribosomal_S7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036823">
        <property type="entry name" value="Ribosomal_S7_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11205">
        <property type="entry name" value="PTHR11205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00177">
        <property type="entry name" value="Ribosomal_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002122">
        <property type="entry name" value="RPS7p_RPS7a_RPS5e_RPS7o"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47973">
        <property type="entry name" value="SSF47973"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01029">
        <property type="entry name" value="rpsG_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00052">
        <property type="entry name" value="RIBOSOMAL_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6 8" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="6" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_S7" evidence="9">
        <location>
            <begin position="1"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003620"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ42402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="156" mass="17687" checksum="D495CC9DFDF4239D" modified="2010-01-19" version="1">MPRRRVIGQRKILPDPKFKSELLAKFVNILMVDGKKSTAEKIVYTALDTMAERSGEEHLAVFEKALENVRPAVEVKSRRVGGSTYQVPVEVRPVRRNALAMRWLVEAARKRGEKSMAARLAAEMLDAADNKGSAVKKREDVHRMADANKAFAHYRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1R2</accession>
    <name>D0Z1R2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003476</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303555.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003476"/>
    <dbReference type="EnsemblBacteria" id="EEZ42443">
        <property type="protein sequence ID" value="EEZ42443"/>
        <property type="gene ID" value="VDA_003476"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2244">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="564091at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="144"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="169"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="208"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="238"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="272"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="311"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="344"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="368"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="395"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="419"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="449" mass="49798" checksum="8977DF99573B8B00" modified="2010-01-19" version="1">MSYASAILIYSFGLIISKLIGLLMQPFVTSQLGIENYARLDILIVTSSIASIIVTFGLIDGICRFAHDEKYRQDDCLSTAMGLVFWGGGLFTSIALLNGHVIQQLLPGSPPLWALYLTFINLYLNALAAIPLTKLRMQHRPIKFAIAQAVFAITQAIGIIVLIPRFQVTGIFIAAVASQLLQLIILYRDLPNLKLIYSSIFIRYGSSIMLSGVLGFICLGAERWAIAYYLGLEFLTPYAIAMQWAIAASLLLEPFSLWWFPKRFNLLKNEKLLADITILGCQICVLICAIVTMLGPLFLRFWLSASFSQSANLIGLIAIMIMLKGISTLLNIGCYYQASGQRIIQINLVATGLSIINIFMILPPFGLLGIIWGSIVIQAIKVFAFYYWSQKELPLPYPLSRLFIALMLLAGIFASSALILIQALLLILLIGLIITPFFLTRISYWSNTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1U2</accession>
    <name>D0Z1U2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">dTTP/UTP pyrophosphatase</fullName>
            <shortName evidence="3">dTTPase/UTPase</shortName>
            <ecNumber evidence="3">3.6.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Nucleoside triphosphate pyrophosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Nucleotide pyrophosphatase</fullName>
            <shortName evidence="3">Nucleotide PPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_003506</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>H2O + UTP = diphosphate + H(+) + UMP</text>
            <dbReference type="Rhea" id="RHEA:29395"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="EC" id="3.6.1.9"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>dTTP + H2O = diphosphate + dTMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:28534"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37568"/>
            <dbReference type="ChEBI" id="CHEBI:63528"/>
            <dbReference type="EC" id="3.6.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Maf family. YhdE subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.9" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303635.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003506"/>
    <dbReference type="EnsemblBacteria" id="EEZ42473">
        <property type="protein sequence ID" value="EEZ42473"/>
        <property type="gene ID" value="VDA_003506"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0424">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1469203at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036218">
        <property type="term" value="F:dTTP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035529">
        <property type="term" value="F:NADH pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036221">
        <property type="term" value="F:UTP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00555">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00528">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029001">
        <property type="entry name" value="ITPase-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003697">
        <property type="entry name" value="Maf-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43213">
        <property type="entry name" value="PTHR43213"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02545">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006305">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52972">
        <property type="entry name" value="SSF52972"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00172">
        <property type="entry name" value="maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 3" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="73"/>
        </location>
    </feature>
    <feature type="site" description="Important for substrate specificity" evidence="3">
        <location>
            <position position="15"/>
        </location>
    </feature>
    <feature type="site" description="Important for substrate specificity" evidence="3">
        <location>
            <position position="74"/>
        </location>
    </feature>
    <feature type="site" description="Important for substrate specificity" evidence="3">
        <location>
            <position position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ42473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="193" mass="21498" checksum="0069C7605CF99A86" modified="2010-01-19" version="1">MSSTIQVYLASGSPRRQELLTQLGYQFERAVVDVEECHQAGETPEQYVQRLAKDKALAGVAVTDGHTPVIGSDTIVVVDDTILEKPIDFNDAKRMLELLSGRKHQVMTAVTVATQERQQTRLVITDVWFKTLSDNEIKNYWQSGEPQDKAGSYGIQGIGGKFIERIDGSYYAVMGLPLVETDIMVQEFLSLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1Z2</accession>
    <name>D0Z1Z2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Radical activating enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">VDA_001978</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the organic radical-activating enzymes family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001978"/>
    <dbReference type="EnsemblBacteria" id="EEZ40946">
        <property type="protein sequence ID" value="EEZ40946"/>
        <property type="gene ID" value="VDA_001978"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1180">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034457">
        <property type="entry name" value="Organic_radical-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012839">
        <property type="entry name" value="Organic_radical_activase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001989">
        <property type="entry name" value="Radical_activat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023912">
        <property type="entry name" value="YjjW_bact"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30352">
        <property type="entry name" value="PTHR30352"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000371">
        <property type="entry name" value="PFL_act_enz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00392">
        <property type="entry name" value="YjjI_activase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04041">
        <property type="entry name" value="activase_YjjW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01087">
        <property type="entry name" value="RADICAL_ACTIVATING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="10">
        <location>
            <begin position="15"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="9">
        <location>
            <begin position="38"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="9">
        <location>
            <begin position="69"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ40946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="294" mass="33404" checksum="72DF33C9A37C20F3" modified="2010-01-19" version="1">MTEAIINRILPFSCVDGPGNRLVIFFQGCNYQCKNCHNPYTIDMCNHCGDCIETCPTQALTLEIIDNKKNIVWDSRTCIECDTCLETCSRQSTPKAERYTVEQIMVLIEKHQLFINGITVSGGESTLQLAFIVELFKAVKQTPHLHHLTCMIDSNGSLGIQGWLKVLPYLDGAMLDLKAWQNDIHHELTGHSNHRVFQSIRLLAEYGKLHELRLLLIPSITDFDTNIEELALFINQIQTDNLVNIRLNAFQHHGVTGEALNWPVCRQGDVEFLAQQLIQRGVQNILLPVIYLNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z204</accession>
    <name>D0Z204_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_001965</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001965"/>
    <dbReference type="EnsemblBacteria" id="EEZ40933">
        <property type="protein sequence ID" value="EEZ40933"/>
        <property type="gene ID" value="VDA_001965"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0628">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002549">
        <property type="entry name" value="AI-2E-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21716">
        <property type="entry name" value="PTHR21716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01594">
        <property type="entry name" value="AI-2E_transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="67"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="156"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="217"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="245"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="314"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="371" mass="39612" checksum="753C70B22260CAFA" modified="2010-01-19" version="1">MEQRQNKLFVNNMVESAIRIGLLLVLIIWTYDIVKPFIIPVLWGAIIAVALMPLTDKLQAVFKGRRGLAATVIALVCIALLIAPFVMVSGSIYDGITHTMSVLQSGDIKIPGPTQRIADIPVVGDKIYEVWSLFATNMEKAVTNFLPEIKTAVGTLASILGSSLASLVVFIIALAVAGGFMTHSHKITEAIQKVSIRTVGKNGAKWTTLTAATIRSVLLGVVGVAFIQAMIIGSAMFAFHVPMAGLLTLGVLILCIAQLPALIVIAPVIFYVYSTGDGTSTTIFTIWALAGGLADNILKPMLMGRGVDVPMPVILIGAIGGMLFSGIIGLFLGAVILAIWYELFMAWLKADAETTQAVVEETQCEKEAKEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z241</accession>
    <name>D0Z241_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001777</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298680.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001777"/>
    <dbReference type="EnsemblBacteria" id="EEZ40745">
        <property type="protein sequence ID" value="EEZ40745"/>
        <property type="gene ID" value="VDA_001777"/>
    </dbReference>
    <dbReference type="GeneID" id="57342118"/>
    <dbReference type="eggNOG" id="ENOG50339TV">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2062732at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025346">
        <property type="entry name" value="DUF4250"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14056">
        <property type="entry name" value="DUF4250"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="62" mass="7260" checksum="411DC5095C7E4CE8" modified="2010-01-19" version="1">MEINNLLGMDGNIVIGIVNERLRLECCSMDELVSRYELDQDELTEKMAQMGYQYDPLTNQFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z248</accession>
    <name>D0Z248_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Phosphate transport system permease protein PstA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_001784</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell inner membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298694.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001784"/>
    <dbReference type="EnsemblBacteria" id="EEZ40752">
        <property type="protein sequence ID" value="EEZ40752"/>
        <property type="gene ID" value="VDA_001784"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0581">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1763210at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:inorganic phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035435">
        <property type="term" value="P:phosphate ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005672">
        <property type="entry name" value="Phosphate_PstA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00974">
        <property type="entry name" value="3a0107s02c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="66"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="116"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="140"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="190"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="258"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="8">
        <location>
            <begin position="70"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ40752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="288" mass="31601" checksum="1EFAC78579E0027B" modified="2010-01-19" version="1">MSLVFANQKNQRIKDIIAQGVIWLSASITVGFLLWVVWYILSNGLSHVNWSFITSDYTTLGEESGIWPMIVSTIYMVIASIAVAAPLGIMTAIYLTEYAKVGSRLVKVIRFCTESLAGIPSIIYGLFGMTFFVVVLGFGYSILAGALTLSILILPVIIRTTEEALMAVPQTYREGSYGLGASKIYTIWRLILPSAMPGIVTSIILSVGRVIGESAPVFLTAGMVARIPESAFDSGRTLTVHLYKLTQELYTVHEWNQAYATATILIVVVLIINLITKLIARRFNTATY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z298</accession>
    <name>D0Z298_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Metal-dependent hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000549</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304692.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000549"/>
    <dbReference type="EnsemblBacteria" id="EEZ39529">
        <property type="protein sequence ID" value="EEZ39529"/>
        <property type="gene ID" value="VDA_000549"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1574">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="751534at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013108">
        <property type="entry name" value="Amidohydro_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07969">
        <property type="entry name" value="Amidohydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro_3" evidence="1">
        <location>
            <begin position="54"/>
            <end position="553"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="555" mass="62718" checksum="6942395F0EEC42C9" modified="2010-01-19" version="1">MKIYKAKKIYTVDNDFSCEEAMAVDGDKIIGLGDLDSLINKYPTATINYDYQEQYIYPGFIEPHLHILGTAAMFATLIPASFTDWTIDGRVYTAVRDSESFLSALKSRVEEFKDRETLVVWGHYEPLHGPLTTAMLDEIDNSRPFAVWGASIHKLTMNSKAIEEFKVNELPDDIFGFLRGDDGKSTGVLIEQAMFKIAAEHILTKATPADIMKGLESVLAQGRNKGVTSCVDMGVGITMPLEAELQLLRASENVPNMPKCRKGYMFGWQKVYEAKDWSAQTTFDYVNQHYLDNKDNQTLFPVKSIKFFADGAVSDYEIITKEPFQDGRETGWLHRFADRTEDTLPEDMQMFWDNDFNIAIHTQGDLAHAKVLDALESLSADGQGRDGQMFIQHMGFTDDEFFERVKEMPYKPSASITPYYSYHFYESWKKEQLLPKSCFSQLQRARSAVDAGMKISVNADIPLMPTNPMMGAYIVMSRRDFHGTEVLPQESISREEALRCITSDAAEQHLLNQIGTLEPGKLADFTVLDFDWMTGDIEQLKQLNATACFVGGEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2C7</accession>
    <name>D0Z2C7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000578</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304755.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000578"/>
    <dbReference type="EnsemblBacteria" id="EEZ39558">
        <property type="protein sequence ID" value="EEZ39558"/>
        <property type="gene ID" value="VDA_000578"/>
    </dbReference>
    <dbReference type="GeneID" id="57343208"/>
    <dbReference type="eggNOG" id="COG3157">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1153621at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036624">
        <property type="entry name" value="Hcp1-lik_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008514">
        <property type="entry name" value="T6SS_Hcp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05638">
        <property type="entry name" value="T6SS_HCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141452">
        <property type="entry name" value="SSF141452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03344">
        <property type="entry name" value="VI_effect_Hcp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="172" mass="19127" checksum="F90EF21A0EF8DC25" modified="2010-01-19" version="1">MPTPCYISIQGKTQGNITAGAFTADSVGNIYVEGHEDQMLVQEFKHIVTVPTDPQSGQPAGQRVHKPFKFTVALNKAVPLMYNSLASGEMLPKVELKWYRTSVEGKQEHYFTTTLTDATIVDINTHMPHCQDPSKADFTQLIEVSMAYRKINWDHTISGTSGADDWRAPLEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2F0</accession>
    <name>D0Z2F0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DNA-binding response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_000601</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="SMR" id="D0Z2F0"/>
    <dbReference type="STRING" id="675817.VDA_000601"/>
    <dbReference type="EnsemblBacteria" id="EEZ39581">
        <property type="protein sequence ID" value="EEZ39581"/>
        <property type="gene ID" value="VDA_000601"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="20"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="146"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="146"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ39581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="249" mass="28181" checksum="64657C134B9EA8EA" modified="2010-01-19" version="1">MATHNHNHLGCIRTMTETYSLLIIEDDLKLQQMLADYFLTQGFTVQTHSDGNGAIELIESSNPDIVLLDLMLPGNDGLTICRQVRGKYQGKLMMLTASNDDFDHVAALEIGADDYVVKPIKPRVLLARMRMLLRRAKIQPDTPVNLNVLTYGNLTLHKNRKLCEFSGQKICMTDSEFDLLWLLASSPDAPLSRDFLTKELRGIEYDGIDRTIDNKIVSLRKKLLDDSSTPQRIITVRGKGYLFVPDTWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2L3</accession>
    <name>D0Z2L3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Methylenetetrahydrofolate reductase</fullName>
            <ecNumber evidence="8">1.5.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_000664</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2 8">
            <text>(6S)-5-methyl-5,6,7,8-tetrahydrofolate + NAD(+) = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:19821"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:18608"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.5.1.20"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>(6S)-5-methyl-5,6,7,8-tetrahydrofolate + NADP(+) = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:19817"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:18608"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.5.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 8">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4 8">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the methylenetetrahydrofolate reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.20" evidence="8"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304991.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000664"/>
    <dbReference type="EnsemblBacteria" id="EEZ39644">
        <property type="protein sequence ID" value="EEZ39644"/>
        <property type="gene ID" value="VDA_000664"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0685">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1425269at2"/>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106312">
        <property type="term" value="F:methylenetetrahydrofolate reductase NADH activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106313">
        <property type="term" value="F:methylenetetrahydrofolate reductase NADPH activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006555">
        <property type="term" value="P:methionine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029041">
        <property type="entry name" value="FAD-linked_oxidoreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003171">
        <property type="entry name" value="Mehydrof_redctse-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02219">
        <property type="entry name" value="MTHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51730">
        <property type="entry name" value="SSF51730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0274">FAD</keyword>
    <keyword evidence="5 8" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ39644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="339" mass="38732" checksum="7217E4CCFA03E913" modified="2010-01-19" version="1">MQPITNYQALSLQDSELRVRYNDVTRGVYFIGTTPPKTSTDLSDVDGIADKLVDRIKDLAFDGLIVYDIQDEGSRISKPRPFPFKSTHDPRYYSSLLNKKTGRPVITYKSVVQSEPEVFNQWLNEAWEQYQVRDIVLVGSPSTQNQVSLPLHEAYKTIADNEHPFFTGGIMIAERHAKKGNEHQRLIEKYQQGCNFFISQAIYDTQATIDLLTRYAIECQEKGLKPQRIILTFSPCGSAKTLEFIEWLGVSVPEATSLRILNADNPLHESIKMCCNSLNQILEAVVEYDLPLGLNIESLTNRKEEIEGSILLYKLLRSTMDMYLAQHEFRKQQGLKKAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2Q8</accession>
    <name>D0Z2Q8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Heat shock protein A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_000709</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the small heat shock protein (HSP20) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305122.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="SMR" id="D0Z2Q8"/>
    <dbReference type="STRING" id="675817.VDA_000709"/>
    <dbReference type="EnsemblBacteria" id="EEZ39689">
        <property type="protein sequence ID" value="EEZ39689"/>
        <property type="gene ID" value="VDA_000709"/>
    </dbReference>
    <dbReference type="GeneID" id="57342963"/>
    <dbReference type="eggNOG" id="COG0071">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1523369at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06470">
        <property type="entry name" value="ACD_IbpA-B_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002068">
        <property type="entry name" value="A-crystallin/Hsp20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037913">
        <property type="entry name" value="ACD_IbpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00011">
        <property type="entry name" value="HSP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="SSF49764"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01031">
        <property type="entry name" value="SHSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="SHSP" evidence="4">
        <location>
            <begin position="29"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="140" mass="16054" checksum="A14226F6D013D2BB" modified="2010-01-19" version="1">MRNVDLTPLYRSAIGFDRLFNQIESSIKKSQSGGFPPYNIEQKDEHHYCITMAVAGFSEDQLDITQEENMLIVAGEQSSDEKKNFIYQGIAERNFERKFQLADNVKVLGAHLENGLLHIDLEREQIEKAQPRKIEIGQKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2U2</accession>
    <name>D0Z2U2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000743</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305227.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39723">
        <property type="protein sequence ID" value="EEZ39723"/>
        <property type="gene ID" value="VDA_000743"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2045999at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="208" mass="24265" checksum="B453395CCEA9A4EE" modified="2010-01-19" version="1">MNDNQFYVEMVGNLVWPVVVIICVFIIKDKIQKIGLKLAKYKDAELHFSDQQTAKPNSTVQQDLQRLIPIDSTGFRKEVEDRLQDSLVQITSDEEKIDILVKNLAQEQLNRAFETIYYNIFGTQIRLLEFLSVQESGAVKTTDILPFFEECKKSNPQTFSKSNLSDYLNFLHTWELLEFDADQYIITKKGRAFLRYITAMQFNKNKAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2X6</accession>
    <name>D0Z2X6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Maltose operon periplasmic protein MalM</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000777</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305323.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000777"/>
    <dbReference type="EnsemblBacteria" id="EEZ39757">
        <property type="protein sequence ID" value="EEZ39757"/>
        <property type="gene ID" value="VDA_000777"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502Z7PA">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="799036at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010794">
        <property type="entry name" value="MalM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07148">
        <property type="entry name" value="MalM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018860" evidence="1">
        <location>
            <begin position="21"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="271" mass="29378" checksum="D7CEF8B59031927A" modified="2010-01-19" version="1">MNKAVALAISAVLLSGCAQQTQSLDTSVAQAQIKQSSGIHWQPLNIPTKVTFTLDKNSQTSQQFNSAGAIAAFQIPANRGAITVDLQSIIDQGVYAPNIAFVDNKGEVLQTFSFADFSYKPAKFLDGDLLEGKFTFLPPITETTVNMVIYTTTKDLAQKTEVLHPAKAYAIAHGNVPPEIPNPEVNHSPYGKLNLSISTPYLTHQPQAQASVVVADQAPTLDETKSYYLDGIKQAVKKNDIEKAMKLLDEAERLGIDKARSVFITTVKAQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2Z2</accession>
    <name>D0Z2Z2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TonB system biopolymer transport component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000793</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000793"/>
    <dbReference type="EnsemblBacteria" id="EEZ39773">
        <property type="protein sequence ID" value="EEZ39773"/>
        <property type="gene ID" value="VDA_000793"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3883">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036305">
        <property type="entry name" value="RGS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016866">
        <property type="entry name" value="UCP028069"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11932">
        <property type="entry name" value="DUF3450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028069">
        <property type="entry name" value="UCP028069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48097">
        <property type="entry name" value="SSF48097"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019955" evidence="2">
        <location>
            <begin position="20"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="43"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="260" mass="29131" checksum="1CF5E44255ADABFB" modified="2010-01-19" version="1">MKKTCIALLVLSASGTVTANSLDTARSIESKTNAASAVSQDRIDKSADSALNMKAEIERLEEETKNLAIYHDHLARLVENQQQEMVHINQQINDIKETRQGIVPLMYQMLDGLEQVIKQDKPIKEEQRVARLHKLQAMMDQADISDAEKFRRLLEAYQIEMDYGTKLATYQAKITLSDNKIIEANILHLGRLVLVARSLDGQQYWSWNAKNKSWQSVDGDQADNIAQAYAMANKDITPNLLTLPISPSHLSLTQAAGATQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z321</accession>
    <name>D0Z321_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Histone acetyltransferase HPA2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000822</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305441.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39802">
        <property type="protein sequence ID" value="EEZ39802"/>
        <property type="gene ID" value="VDA_000822"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1390922at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="166" mass="18937" checksum="1F6DB16343142453" modified="2010-01-19" version="1">MFHDSFEFITAPNAQLVSEAEIVFNRQTKNWKSLTDSFLNVVAVNTKQEVIGMASIKGSETQSDYLELGYLFVSSDYRRMGIAAKFTQIRIDYAKKNGVKVLYAIVEPDNHASINNLDKFGFKYYGTYGHIKGLDLSYDWFALVLDETINLDAIMMQLAGPRKRIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z380</accession>
    <name>D0Z380_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Agglutination protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000881</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000881"/>
    <dbReference type="EnsemblBacteria" id="EEZ39861">
        <property type="protein sequence ID" value="EEZ39861"/>
        <property type="gene ID" value="VDA_000881"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1538">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019867">
        <property type="term" value="C:outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010130">
        <property type="entry name" value="T1SS_OMP_TolC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01844">
        <property type="entry name" value="type_I_sec_TolC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="419" mass="47236" checksum="57E4752DB34B7EF3" modified="2010-01-19" version="1">MTMPVMAQSLEQAVAETLASNPEIKSAFNEFMSRNSMIDAAKGDYLPSVDLRAGVGYNNYDNEFGTKGEYDPKQAEISIRQLLWDGSITWNNINRNQSETEAQRYQLLSDAQDKALKTAEVYLDVLRAEAVLKLSESNYKVHQHMYVDIKKRADAGIGSTADLAQVEGRLARSKTNLLAAQSNLNDKKTEFARTVGTFPDDLVTPEVDTNFIPTSLDDAMKIAQKNNPVMYVASNDIDAAEYQYKQAKGNFYPTFDIEASQEWGNELNGSRGDTDEFKAMLNMRYNLFNGGSDAAKSRQAAYQLNKSKDIRDRALRMLKEGTKLSWSAMELANSQTKYLQEHVDASARTVIAYEKQFKIGQRSLLDVLNTENELFESRKAYLNAHYDGIFAKYRVLNATGTILNEMRVDIPNEWTESVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3B0</accession>
    <name>D0Z3B0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000911</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305699.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000911"/>
    <dbReference type="EnsemblBacteria" id="EEZ39891">
        <property type="protein sequence ID" value="EEZ39891"/>
        <property type="gene ID" value="VDA_000911"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="234" mass="26345" checksum="AB713A6A3B529D65" modified="2010-01-19" version="1">MTYGIDMRTTNGKRMVWGREEVYLYWGRVEVNYEGNEGKKIHSLFNIPINWSPLVFSRILSNSIPNIVAGKSDGIHMVNKNERLHVESNFEGNSGSRKISYYVFVPAKHIPLPKHGLMVKNDIGNICFHSGRRSLNVKDLLKKTNIGASGVSTTYSYNVAAQTTLTGAARIPISPYQSFGYYRTTLGSERGIHISWFLVESSSNPYPETPTFITASVPLINADEYHDISSLHWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3B4</accession>
    <name>D0Z3B4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000915</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305709.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000915"/>
    <dbReference type="EnsemblBacteria" id="EEZ39895">
        <property type="protein sequence ID" value="EEZ39895"/>
        <property type="gene ID" value="VDA_000915"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG50316KX">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1924229at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="206" mass="23860" checksum="0E3C274FBA1E7BF6" modified="2010-01-19" version="1">MKVKILIDRVSRELVDPRNTRWCRDELTQYLNEAIGVIATKQPGLVAKATDLSVTSSPIDLPRDGYSLLAVHSINGIAAQYVLVEKLDHMYPTWQLDKGVPICWTKREYDLKRFWIYPQPSEPVVVSILYVPEIRISDEEFEVSLPNIYEGALVDFMMYRAYSRDGENVSEANKSQQHFQSFSLFLNDDQALKNNREQRLNQSIFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3B7</accession>
    <name>D0Z3B7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000918</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305716.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000918"/>
    <dbReference type="EnsemblBacteria" id="EEZ39898">
        <property type="protein sequence ID" value="EEZ39898"/>
        <property type="gene ID" value="VDA_000918"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502Z8EY">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="421122at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025267">
        <property type="entry name" value="DUF4043"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13252">
        <property type="entry name" value="DUF4043"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="403" mass="45120" checksum="1D506A73F0CE2B3D" modified="2010-01-19" version="1">MTTITPAQAKHLQEVALFTAANRNRSFVNMLTEEAPKQTSGDKKGNKQTSPHAPIVRVSDLQKQAGESVDMQIIHKLSKRPTMGDRKLEGRGENLEFSSFDLKINQGRHMVDAGGKMSQQRTSHGIRRAGRTLLGPYFNDLQDQIATIQLAGARGDYFDDDIIVPLFDHKEFGEIMVNDITPPTYDRHFFGGDATSFESLDSADIFNMEVVDNMGLYIEEMAHPLQPIRFQADELAGDEPFYLLTVTPRQWATWQKTSSYKDWQQLTAAAINRSRNFRHPVFAGECAMRGNILVRKYKGMPIRFNQGSVVNVSNNDNQATAKQVEAKTTIDRAMLIGGQALANAWGATSSGNQFKYTEKKVDHDNGTEISIAWMNGLKKIRFPDKRGRINDHGVIALDTAINI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3D7</accession>
    <name>D0Z3D7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative integrase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_000938</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305777.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000938"/>
    <dbReference type="EnsemblBacteria" id="EEZ39918">
        <property type="protein sequence ID" value="EEZ39918"/>
        <property type="gene ID" value="VDA_000938"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0582">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="785253at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044068">
        <property type="entry name" value="CB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022000">
        <property type="entry name" value="Min27-like_integrase_DNA_bind"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12167">
        <property type="entry name" value="Arm-DNA-bind_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51900">
        <property type="entry name" value="CB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0229">DNA integration</keyword>
    <keyword evidence="3" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core-binding (CB)" evidence="6">
        <location>
            <begin position="83"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="Tyr recombinase" evidence="5">
        <location>
            <begin position="199"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="428" mass="48601" checksum="2AE8815F21419CC0" modified="2010-01-19" version="1">MSMYPEGIEVRGKSIRITFYFKGKRCRETLTGWDVTPSNIKKAGRLRAVIVSEIACGKFNYLERFPNSKNTLQISVQNPHVDCSLNDFIEHFLLIKSVELTESSIIRTRSGLKTCAKLLGGERLISNITHADIMSMRLKLLNGSNFSPSPIRRTSNGRSVKTVNTYLTICSSLFKYAYRTEAIHTNPFDGVSRLRTVKTPPNPLEHDEFIRLINHPSIREQDVNLWTVAVYTGLRHGELSALAWEDIDLVKRTITVKRTATQQKRFRVPKTESGERTINLLAPAYEALVRQKACTFLYPSIAVEVESRQKRNHIQEQCTWVFRMTSYSAEAKGNISTKVISNMWRKCTKLAGIAYRNPYQTRHTYACWLLNSGANPAFIASQMGHSDMSMVISVYGAWMPSNNESEIAKIERQLNCIAPSAPHQKKTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3E8</accession>
    <name>D0Z3E8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000949</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39929">
        <property type="protein sequence ID" value="EEZ39929"/>
        <property type="gene ID" value="VDA_000949"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031NE3">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2177662at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018812" evidence="2">
        <location>
            <begin position="21"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="20"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="105" mass="11906" checksum="1074019F580947E8" modified="2010-01-19" version="1">MKFVKILPLLCMVMASTAQADNLVDRLNQVDQGLQSAQNAVNSTQNSIRDGQNRIDNTQRSIDEIKDGTYVENRVNNKVRNTKRRAVDNLIQRSNNAIRKATNTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3G4</accession>
    <name>D0Z3G4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000965</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305853.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39945">
        <property type="protein sequence ID" value="EEZ39945"/>
        <property type="gene ID" value="VDA_000965"/>
    </dbReference>
    <dbReference type="GeneID" id="57342567"/>
    <dbReference type="eggNOG" id="ENOG5031UMT">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1301579at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="192" mass="22042" checksum="466DEF4DAD8CFE2B" modified="2010-01-19" version="1">MIRESVFSSYDKWSKPLVSEVAEVVNLLKEHGYDSKKLALVTGLQEKNINSWTANYKKEPLDVSTIPYPCWCFLSALAGIPNISTNEKIIEVDDIRRVLRLFKPTAFGPRNTFVCPTPEQFSKLIDSGLYPEMTAENICQLHNWNPAKFIDSINTGKLPFLNWCLIIMMFGINLQKMILKDLEAPFVYEFIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3J7</accession>
    <name>D0Z3J7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptide methionine sulfoxide reductase MsrA</fullName>
            <shortName evidence="4">Protein-methionine-S-oxide reductase</shortName>
            <ecNumber evidence="4">1.8.4.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Peptide-methionine (S)-S-oxide reductase</fullName>
            <shortName evidence="4">Peptide Met(O) reductase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">msrA</name>
        <name evidence="6" type="ORF">VDA_000998</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>[thioredoxin]-disulfide + H2O + L-methionine = [thioredoxin]-dithiol + L-methionine (S)-S-oxide</text>
            <dbReference type="Rhea" id="RHEA:19993"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58772"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 4">
            <text>[thioredoxin]-disulfide + H2O + L-methionyl-[protein] = [thioredoxin]-dithiol + L-methionyl-(S)-S-oxide-[protein]</text>
            <dbReference type="Rhea" id="RHEA:14217"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12315"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:44120"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the MsrA Met sulfoxide reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.11" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305948.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000998"/>
    <dbReference type="EnsemblBacteria" id="EEZ39978">
        <property type="protein sequence ID" value="EEZ39978"/>
        <property type="gene ID" value="VDA_000998"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0225">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1554384at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033744">
        <property type="term" value="F:L-methionine:thioredoxin-disulfide S-oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008113">
        <property type="term" value="F:peptide-methionine (S)-S-oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01401">
        <property type="entry name" value="MsrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002569">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036509">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01625">
        <property type="entry name" value="PMSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55068">
        <property type="entry name" value="SSF55068"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00401">
        <property type="entry name" value="msrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PMSR" evidence="5">
        <location>
            <begin position="45"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ39978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="209" mass="23357" checksum="B868D6EF45BB9AF9" modified="2010-01-19" version="1">MLNDKQIKIDASNALAGRKNSIIPPTHHYVLKTPLDTVPNHCDFIILGMGCFWGAERLFWQVDGVYSTAVGYSGGYTENPTYQEVCSGQTGHAEVVKIVFDPTVVSLEQLLALFWEKHNPTQGMRQGNDIGPQYRSVIYTHSSEQELAAISSRNRYQQALTKMGDDHLITTEIEPASTFYFAEEYHQQYLAKNPDGYCGLGGLSVCFPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3L6</accession>
    <name>D0Z3L6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">NhaP-type Na+/H+ and K+/H+ antiporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_001017</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305996.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001017"/>
    <dbReference type="EnsemblBacteria" id="EEZ39997">
        <property type="protein sequence ID" value="EEZ39997"/>
        <property type="gene ID" value="VDA_001017"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0025">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1194802at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015299">
        <property type="term" value="F:solute:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003148">
        <property type="entry name" value="RCK_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02254">
        <property type="entry name" value="TrkA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51201">
        <property type="entry name" value="RCK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0050">Antiport</keyword>
    <keyword evidence="4" id="KW-0406">Ion transport</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="58"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="119"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="151"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="185"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="220"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="270"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="294"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="329"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="362"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="domain" description="RCK N-terminal" evidence="7">
        <location>
            <begin position="398"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ39997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="596" mass="65520" checksum="C966E58AAD7BE0EF" modified="2010-01-19" version="1">MHEEMIGLTLAGLGVLGLGCQWLAWRLKLPAILFLLIAGIVIGPVTGIFQPNDMFGDLLFPLISLSVAIILFEGSLTLNFKEIREVNKTVQSIVSIGAVVTWLITSTATHYLLDLSWSMSFLFGSMTVVTGPTVIVPLLRTVRPQAKLANILRWEGILIDPIGALFVVLVYEFMVSSSEVHSLEVFALILAVGLIFGALAGWFIAVVLRRHLLPEYLQPFAVLAVVLGVFAGSNAIESEAGLLAVTVMGMWLANAKEVNIQHILHFKENLTILLISGLFLLLAARIDLTDFKALGFSAAALFIIIQFVARPASIFLSTLRSGLECKEKLFLAWVAPRGIVAAAISSLFAIKLSQAGIKEAELLVPLTFMVIIGTVVLQSISARPMAKLLKVAEPSPRGFLIVGANDVARTIGIELKKYDCRVVMTDSNWDYIRNARMAGLDTYYGNPVSSHADEYLNLIGVGKVLAMTPDKHLNVVACMHFMNDFGERSVYSLYGNRSNSNFNEKHYAAQERHGLTLFNQDVSYKKLASFINQGAEVRHTKISEAFSLEDYYEQYKTAQIIPLFAVDPKLNIHVFSSTIQPDVKAGWTMISLIKEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3U6</accession>
    <name>D0Z3U6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Superoxide dismutase [Cu-Zn]</fullName>
            <ecNumber evidence="4">1.15.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_001099</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Destroys radicals which are normally produced within the cells and which are toxic to biological systems.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>2 H(+) + 2 superoxide = H2O2 + O2</text>
            <dbReference type="Rhea" id="RHEA:20696"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:18421"/>
            <dbReference type="EC" id="1.15.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
        <text evidence="4">Binds 1 copper ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="4">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the Cu-Zn superoxide dismutase family.</text>
    </comment>
    <dbReference type="EC" id="1.15.1.1" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306216.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001099"/>
    <dbReference type="EnsemblBacteria" id="EEZ40077">
        <property type="protein sequence ID" value="EEZ40077"/>
        <property type="gene ID" value="VDA_001099"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2032">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2015673at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004784">
        <property type="term" value="F:superoxide dismutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00305">
        <property type="entry name" value="Cu-Zn_Superoxide_Dismutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036423">
        <property type="entry name" value="SOD-like_Cu/Zn_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024134">
        <property type="entry name" value="SOD_Cu/Zn_/chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018152">
        <property type="entry name" value="SOD_Cu/Zn_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001424">
        <property type="entry name" value="SOD_Cu_Zn_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10003">
        <property type="entry name" value="PTHR10003"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00080">
        <property type="entry name" value="Sod_Cu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49329">
        <property type="entry name" value="SSF49329"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00087">
        <property type="entry name" value="SOD_CU_ZN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00332">
        <property type="entry name" value="SOD_CU_ZN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0186">Copper</keyword>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="2 4" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019978" description="Superoxide dismutase [Cu-Zn]" evidence="5">
        <location>
            <begin position="21"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="Sod_Cu" evidence="6">
        <location>
            <begin position="37"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="171" mass="17946" checksum="5CA2318E5CD4A2D6" modified="2010-01-19" version="1">MYKKVLLGALTLALSQQVFAQDLVVNMTDLQTGKTVGHITLSQNEYGVVFTPDLADLTPGMHGFHVHQNGSCGSIEKDGKTILGGAAGGHYDPEKTGKHGYPWSTDNHKGDLPALFVSANGLATNPVLAPRLTLKELKGHAIMIHAGGDNYSDMPKPLGGGGARMACGVVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3V9</accession>
    <name>D0Z3V9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Enoyl-[acyl-carrier-protein] reductase [NADH]</fullName>
            <shortName evidence="9">ENR</shortName>
            <ecNumber evidence="9">1.3.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">fabV</name>
        <name evidence="12" type="ORF">VDA_001112</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2,3-saturated acyl-CoA + NAD(+) = a (2E)-enoyl-CoA + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:18177"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58856"/>
            <dbReference type="ChEBI" id="CHEBI:65111"/>
            <dbReference type="EC" id="1.3.1.44"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a 2,3-saturated acyl-[ACP] + NAD(+) = a (2E)-enoyl-[ACP] + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:10240"/>
            <dbReference type="Rhea" id="RHEA-COMP:9925"/>
            <dbReference type="Rhea" id="RHEA-COMP:9926"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:78784"/>
            <dbReference type="ChEBI" id="CHEBI:78785"/>
            <dbReference type="EC" id="1.3.1.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="9">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 9">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the TER reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.9" evidence="9"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306254.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001112"/>
    <dbReference type="EnsemblBacteria" id="EEZ40090">
        <property type="protein sequence ID" value="EEZ40090"/>
        <property type="gene ID" value="VDA_001112"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3007">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="678530at2"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004318">
        <property type="term" value="F:enoyl-[acyl-carrier-protein] reductase (NADH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016631">
        <property type="term" value="F:enoyl-[acyl-carrier-protein] reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050343">
        <property type="term" value="F:trans-2-enoyl-CoA reductase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01838">
        <property type="entry name" value="FabV_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024906">
        <property type="entry name" value="Eno_Rdtase_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024910">
        <property type="entry name" value="Enoyl-CoA_Rdtase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010758">
        <property type="entry name" value="Trans-2-enoyl-CoA_reductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37480">
        <property type="entry name" value="PTHR37480"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07055">
        <property type="entry name" value="Eno-Rase_FAD_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12242">
        <property type="entry name" value="Eno-Rase_NADH_b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12241">
        <property type="entry name" value="Enoyl_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="4 9" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="3 9" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7 9" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6 9" id="KW-0520">NAD</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl_reductase" evidence="11">
        <location>
            <begin position="84"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="Eno-Rase_FAD_bd" evidence="10">
        <location>
            <begin position="328"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="9">
        <location>
            <position position="237"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="48"/>
            <end position="53"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="75"/>
            <end position="76"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="112"/>
            <end position="113"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="141"/>
            <end position="142"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="227"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="275"/>
            <end position="277"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="site" description="Plays an important role in discriminating NADH against NADPH" evidence="9">
        <location>
            <position position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF12241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ40090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="400" mass="44597" checksum="89C993575F72D7BF" modified="2010-01-19" version="1">MIITPIIDSNVARSCHPLGCHEMIKQQVKTIKNSLGASRNKQNVLILGASSGFGLAARICLTFGGGQANTLGVSYERGPSDKNIGTAGWYNNIYFKQEAERHGYQAINIVGDAFAKSTRQQVAEAIQQKFNGKVDLVIYSLATGARPNPIDGTLWRSTIKPIKEVQTGYNLNLEHETLDLVDIPPATTKEIEDTVKVMGGEDWQEWVDFLQSKDLLASGCQTLAFSYIGSPLTHNIYHRGTLGAAKEHLHQSVTTLNQQLAPIQGSAHVVVCKALVTKASAFIPTFSPYMLALYQVMKQQGLHEGCLKQMQRLFKEKLSTNKDEIQSDANGLIRLDDWELRPEVQQQTAELIKKITPDNFKDISDYQQYRQEFMQLNGFEVPNINYEQSVDVAELLKLKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z402</accession>
    <name>D0Z402_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATPase associated with various cellular activities AAA_5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001155</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306365.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001155"/>
    <dbReference type="EnsemblBacteria" id="EEZ40133">
        <property type="protein sequence ID" value="EEZ40133"/>
        <property type="gene ID" value="VDA_001155"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0714">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="895310at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045427">
        <property type="entry name" value="MoxR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041538">
        <property type="entry name" value="RavA-like_AAA_lid"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17868">
        <property type="entry name" value="AAA_lid_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20030">
        <property type="entry name" value="bpMoxR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="34"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="301" mass="33804" checksum="BD204F4B1465D292" modified="2010-01-19" version="1">MELRDKLSKLTAALSEGLIERDTEVKLAVLGLLSQENVLFVGPPGTAKSEISRRLVEVVKDASYFEYLLTKFTTPEEVFGPLSISKLKSDVYSRNTQGYMPTSDVVFLDEVFKANSAILNSLLTIMNERIFHNGVNKEQTPLLSMVAASNELPIGHDELSALYDRFLIKKFVSHVSDKNVSKLLQLSPSPFSLSDELKLTRDEIKAISNESKKVEIPKDIEKLIIVIKKEYDSEFVENSDEVLSDRKLVKAIKIMKVSAYTCGRDVLDLSDVSLLRFILWSDSKNINSVNNIINKNLSGRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z431</accession>
    <name>D0Z431_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Beta-lactamase</fullName>
            <ecNumber evidence="3">3.5.2.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_000287</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a beta-lactam + H2O = a substituted beta-amino acid</text>
            <dbReference type="Rhea" id="RHEA:20401"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:35627"/>
            <dbReference type="ChEBI" id="CHEBI:140347"/>
            <dbReference type="EC" id="3.5.2.6"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-A beta-lactamase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.6" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000287"/>
    <dbReference type="EnsemblBacteria" id="EEZ39269">
        <property type="protein sequence ID" value="EEZ39269"/>
        <property type="gene ID" value="VDA_000287"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2367">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008800">
        <property type="term" value="F:beta-lactamase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030655">
        <property type="term" value="P:beta-lactam antibiotic catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045155">
        <property type="entry name" value="Beta-lactam_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000871">
        <property type="entry name" value="Beta-lactam_class-A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35333">
        <property type="entry name" value="PTHR35333"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13354">
        <property type="entry name" value="Beta-lactamase2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00118">
        <property type="entry name" value="BLACTAMASEA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase2" evidence="4">
        <location>
            <begin position="6"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="210" mass="23154" checksum="E48D40F3B97B65E8" modified="2010-01-19" version="1">MADSDKDKSVLTYPVVIKKSELVTYSPVTEKWVGKRFTPKQACDATMTFSDNTAANIVLHAVGGPEQLTEFLRSRVGDSTTRLDRTEPTLNEAKLNDPRDTTTPIAIAETLNKLMLSEHILTKPSQQQLITWMEGNQVAAPLLRSVLPKGWKIADRSGAGGFGSRGITAVVWPTEHEPMVVSIYIQQSSASMDERNKAIATIGKQVFTYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z432</accession>
    <name>D0Z432_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC-type Fe3+ transport system permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_000288</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000288"/>
    <dbReference type="EnsemblBacteria" id="EEZ39270">
        <property type="protein sequence ID" value="EEZ39270"/>
        <property type="gene ID" value="VDA_000288"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037294">
        <property type="entry name" value="ABC_BtuC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000522">
        <property type="entry name" value="ABC_transptr_permease_BtuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30472">
        <property type="entry name" value="PTHR30472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01032">
        <property type="entry name" value="FecCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81345">
        <property type="entry name" value="SSF81345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="80"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="133"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="160"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="257"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="293"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="323"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ39270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="348" mass="36691" checksum="56CE35111E32517B" modified="2010-01-19" version="1">MKLLSRIKPVEIRGDLRLSIKLTAAVMTLLAISSLLLGRYAISFHDLVAALQTALGHPDLESNHYEVIKAVVFHARLPRVITALIVGAGLAIAGSAFQAVFRNPLVSPGLLGVLNGCAFGAALGLVLQAGLYGVPLLACLFGCLAVAIGVLIAKRIGGDSILLLILGGIISNALFAGLLSLVKYMADPENQLPGIIYWLLGSLSSVSLPLLEVTLPIMVIAMALLLVLGRVLDAMSLGDDEALSLGIPVSTMRYGVIFLATIISAITVCIAGVVGWVGLLIPHLTRLIWGASHRFVLPLSALLGAIFLLIADDLARMLTSSEIPLGVVTELLGAVIFFFLLTRTWQAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z469</accession>
    <name>D0Z469_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000325</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304050.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000325"/>
    <dbReference type="EnsemblBacteria" id="EEZ39307">
        <property type="protein sequence ID" value="EEZ39307"/>
        <property type="gene ID" value="VDA_000325"/>
    </dbReference>
    <dbReference type="GeneID" id="57342518"/>
    <dbReference type="eggNOG" id="COG4977">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1268974at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="1">
        <location>
            <begin position="182"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="308" mass="35186" checksum="3754F344578C3C68" modified="2010-01-19" version="1">MYQRAVAQTAKFLMFDMQKLEETQHLIFGADYILIHPNSPGCILHLATHHLKLQPNQIVLLAPFNPFRLSLEKSSCSRRALVNDCDVLHFRLNALGQTFVDSVQFANIRSMLEQAKSGLLFSGEQLSLFKAYFQKMENTFEFKQVLNLLALLDELAAITPERYLINNCIEISNSKRAEDRVQMALKYIENNLAEPLTVTVVAEQLCMAESTFSRFFHANLGVTFRQYLIEQRVKQAARYLVSTDWSVAHIGAEVGFSSLSNFNAKFKSILRVTPREYRTNHLDMRQGIEQTASVQGQVQKQMLELVNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z477</accession>
    <name>D0Z477_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fructose-like phosphotransferase enzyme IIB component 2 (PTS system fructose-like EIIB component 2)</fullName>
            <ecNumber evidence="3">2.7.1.69</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000333</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.1.69" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304073.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000333"/>
    <dbReference type="EnsemblBacteria" id="EEZ39315">
        <property type="protein sequence ID" value="EEZ39315"/>
        <property type="gene ID" value="VDA_000333"/>
    </dbReference>
    <dbReference type="GeneID" id="57342526"/>
    <dbReference type="eggNOG" id="COG1445">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2011067at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103111">
        <property type="term" value="F:D-glucosamine PTS permease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022877">
        <property type="term" value="F:protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05569">
        <property type="entry name" value="PTS_IIB_fructose"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036095">
        <property type="entry name" value="PTS_EIIB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013011">
        <property type="entry name" value="PTS_EIIB_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003501">
        <property type="entry name" value="PTS_EIIB_2/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003353">
        <property type="entry name" value="PTS_IIB_fruc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02302">
        <property type="entry name" value="PTS_IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52794">
        <property type="entry name" value="SSF52794"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00829">
        <property type="entry name" value="FRU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51099">
        <property type="entry name" value="PTS_EIIB_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PTS EIIB type-2" evidence="2">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="104" mass="11141" checksum="4C9AA375774545F3" modified="2010-01-19" version="1">MKLLGVTSCPSGVAHTYMAAEALETAAKAKGWDVKIETQGSIGIENEITLNEVADCDIVILTKDIAIKNEDRFKGKKIVRVGVADAVKKAPQIMDKIEAHFASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4D9</accession>
    <name>D0Z4D9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="12">ATP-dependent RNA helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">VDA_000395</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the DEAD box helicase family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304247.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000395"/>
    <dbReference type="EnsemblBacteria" id="EEZ39377">
        <property type="protein sequence ID" value="EEZ39377"/>
        <property type="gene ID" value="VDA_000395"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0513">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="643629at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7 12" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Q_MOTIF" evidence="11">
        <location>
            <begin position="8"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="39"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="230"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="400"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="6">
        <location>
            <begin position="8"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ39377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="431" mass="47531" checksum="68BCDE43F85EC6A9" modified="2010-01-19" version="1">MTIATALTSFTELALIQPLLARVTESGYQQPTPIQGQVIPNVLAGRDVIAGANTGAGKTAAFALPILQELYSQKQSDQTHGRRGNFVSALVLVPTRELARQVADSITSYSAHFNGAIKTAAVYGGVSTNAQMLELRHGADILVATPGRLLDLVDHNAIKLDRVKTLVLDEADRMLSLGFTEELTNVLNQLPKQKQTLLFSATFPEQVQSLTQDLLNNPVEIQIQSDDASTIEQHVYTVNKGEKTAVLAHLIKQNQWRQALVFVAAKNSCKHLAEKLHKRGIEAEVFHGDKAQSSRTRIIEDFKSGKIEVLIATDIAARGLDIEKLPVVINVDLPRSPSDYMHRIGRSGRAGEAGLAISLIDYEDFHHFKVIEKKNKIRLEREQVAGFEFDEAKAKKMLDVKKPMAKPEGTGKKKRKKKQAAQQADVWLKNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4L9</accession>
    <name>D0Z4L9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DNA-binding response regulator KdpE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_000477</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304472.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000477"/>
    <dbReference type="EnsemblBacteria" id="EEZ39457">
        <property type="protein sequence ID" value="EEZ39457"/>
        <property type="gene ID" value="VDA_000477"/>
    </dbReference>
    <dbReference type="GeneID" id="57342657"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="817710at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="6"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="130"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="130"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="231" mass="26096" checksum="39DCCAA62BECB389" modified="2010-01-19" version="1">MNSDIKILIIEDEAPIRRFLDILTTGHGYQVKTAETAQEGLRQIATWSPNLILLDLGLPDADGLDFTKELRTWTETPIIVISARDKETDKVLALDAGANDYLTKPFGSEELLARIRVALRLTSQTPISDVTSYQFGDVTMDLVMQTVMRGDEAIKLTPKEYKILLLMAKNMGKVLTHKQILKEVWGGNYTEHAHYVRIHIAQLRHKIEYCPAQPKHIITENGVGYRLIADD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4M3</accession>
    <name>D0Z4M3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted deacylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_000481</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304485.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000481"/>
    <dbReference type="EnsemblBacteria" id="EEZ39461">
        <property type="protein sequence ID" value="EEZ39461"/>
        <property type="gene ID" value="VDA_000481"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3608">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="632656at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007036">
        <property type="entry name" value="Aste_AspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043795">
        <property type="entry name" value="N-alpha-Ac-DABA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04952">
        <property type="entry name" value="AstE_AspA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039012">
        <property type="entry name" value="ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="337" mass="37480" checksum="4F15763CB0E6641E" modified="2010-01-19" version="1">MAQTIYTGDTLQSIPVISHLNVSDLPVGCHQFWFSASSNALAQNNLLPVWVFKGAKEGKRLCITAGVHGDEFNGILAAQQCIRELQENIENIQGTVVVVPIVNLSGVLHHHRDFFSSDLDLSSINLNRYFPGNKNGNAAEQYLAAIWSHLLHPNADLAIDLHTQTSGTCYPLYVFADYRLSDAVTMARLIEPDVILDDPGAEGVLETVWNQHQIPSITIEVGCGRITELEFIERAVNGIWRVLEQYNIAVTEEREEPIRAALIEGKEVTSIRALTGGFIIPQVTLLEKVEAEQLVAIQYDIFGQEAHRYYTPKEGIVLSFNIESLREVGSLVVRLIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4R9</accession>
    <name>D0Z4R9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Potassium uptake protein integral membrane component KtrA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000527</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000527"/>
    <dbReference type="EnsemblBacteria" id="EEZ39507">
        <property type="protein sequence ID" value="EEZ39507"/>
        <property type="gene ID" value="VDA_000527"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0569">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006037">
        <property type="entry name" value="RCK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036721">
        <property type="entry name" value="RCK_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003148">
        <property type="entry name" value="RCK_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02254">
        <property type="entry name" value="TrkA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116726">
        <property type="entry name" value="SSF116726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51202">
        <property type="entry name" value="RCK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51201">
        <property type="entry name" value="RCK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0406">Ion transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="RCK N-terminal" evidence="2">
        <location>
            <begin position="15"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="3">
        <location>
            <begin position="146"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="228" mass="25079" checksum="47B4B9BF065C79D7" modified="2010-01-19" version="1">MFHLWGKTMSPEDKQFAIVGLGRFGMSLCKELSAQGAQVLAVDLNEACVKKAADIATQAVVADCSNDETVAELKLDDYDIVMVSIGEDVNASILTTLVLKEAGVKAVWVKAKDDHHAKILSKIGADRIIRPERDMGMRIARNMLDKRIFEFSDLGSGICLAEVVVSRKNMGKQLCEHPCCRRQELQLLALKRGPEVRKNPESGTQLQIGDILIVTGPQAILTETLRHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4S6</accession>
    <name>D0Z4S6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Macrophage infectivity potentiator-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000534</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000534"/>
    <dbReference type="EnsemblBacteria" id="EEZ39514">
        <property type="protein sequence ID" value="EEZ39514"/>
        <property type="gene ID" value="VDA_000534"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2128">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="SSF69118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="92" mass="10466" checksum="D4B147D9148C9B58" modified="2010-01-19" version="1">MKVDPVLIEALRNDDVMPTPKLQALKDLTLSLVRQRGNVSDEELQAFYDAGYGQKQVLEIILGLSQKVISNYVNRVAKTPVDPMFQKFTWTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4U8</accession>
    <name>D0Z4U8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Type III secretion cytoplasmic protein (YscL)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_000181</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SctL stator family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306533.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000181"/>
    <dbReference type="EnsemblBacteria" id="EEZ39165">
        <property type="protein sequence ID" value="EEZ39165"/>
        <property type="gene ID" value="VDA_000181"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1317">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1285795at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030254">
        <property type="term" value="P:protein secretion by the type III secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018035">
        <property type="entry name" value="Flagellar_FliH/T3SS_HrpE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012842">
        <property type="entry name" value="T3SS_SctL/SctL2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02108">
        <property type="entry name" value="FliH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02499">
        <property type="entry name" value="HrpE_YscL_not"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="FliH" evidence="6">
        <location>
            <begin position="83"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="211" mass="23553" checksum="ACA6952DCC32C559" modified="2010-01-19" version="1">MVSFVEIKTDNLQLAPGLKVLKAKDYVSYLDSQHLVEAARSKAESIITKADEAYELERQRGYQDGIDQAKIENAETMLATLARCNEYYLQVEQKMTSVVLDAVRKIINSFDDVDTTASVVREALQLVSNQKQVILHVHPEQVTEVREKVSSILSDFPEVGYVEVIADARLKNGGCILETEVGIIDASIDGQLQALKQAITKQLSERQQIQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4Y6</accession>
    <name>D0Z4Y6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative superfamily I DNA helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000219</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306639.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000219"/>
    <dbReference type="EnsemblBacteria" id="EEZ39203">
        <property type="protein sequence ID" value="EEZ39203"/>
        <property type="gene ID" value="VDA_000219"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0507">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1112">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1502">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="616258at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019637">
        <property type="term" value="P:organophosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025202">
        <property type="entry name" value="PLD-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016834">
        <property type="entry name" value="UCP026306"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="PTHR10887"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13091">
        <property type="entry name" value="PLDc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF026306">
        <property type="entry name" value="UCP026306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PLD phosphodiesterase" evidence="1">
        <location>
            <begin position="1108"/>
            <end position="1130"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="1172" mass="134251" checksum="0FDCC725C9F866C8" modified="2010-01-19" version="1">MNNQGWIHYWRNSLADADSAKGALKKQDLKNYERMTTDEFKEGKLKNDSTLLKELFRNEPDTLTAVQIHHRPVTYNLRKVHGKDYSDNMPGVLTPIVCSLWVNRDGLLFPHITPFIPRDLLAPQGNDTFTISDVDKLDKFLTINEIPAQSTESIPAKFEQEEQYRNHKKDWLNYYELTQKLFADYCDKNRIELFYECIKSRGLVNKTSECLGASRHILKLYDNLSNSSTTLPLLDSYAEKTVTNRDECIDVSQTVNSRFGHSNSQFPLAKAQCDALAHTLAMQEGDILAVNGPPGTGKTTFVLSVVASLWIESALKESQPPLIIAASTNNQAVTNIIDAFGKDFDEGEDELSGRWLPDIFSYGGYLPSAYGELEAAKSYQTKHFYERVEQLDFLEQAQAHYLDKAKQAFPQQNFTDVTQVKAYLLAELRQHKNQLDHIQHNWHHYNSQQNDIHSRLGNNPQQTLAYQQQVVSDAQALKDSAKEKLTAWRSYLCNESIWLTLFKWLPPIKNKLELQRRSFMFDLIEHDEEQIENLSSDRFENLLRQVFSSQKDDFDDQKNRYQDWLEQYQKFEQSQLNWLDSINKFTKYYPEQTIPELTDIDSVLDITTRFRMFRLAVHYWEACWLLSCRDLGQELNEQARKTGVKTVRPRWQRRMMLTPCIVSTFHSLPSHMTYQSHVGNNEFETDYLLNEIDLLIVDEAGQVSPEVAAASFSLAKKALVIGDIYQIPPIRNVCSSIDRGNLKRHKIISSDNEYTVLQEEGRCVVTGSVMHVAQQASRFHYMQEAEPGMFLQEHRRCYDELISYCNDLCYQGILLPKRGQATEDYLYSPFSHLHVDGIVESFSGSQRNKLEAETIAAWLHANKVEIENYYGEPLANCVGIITPFSAQVKQIKTACDKLNIKTGKKDDQLTVGTVHSLQGAERKIIIFSQVYTRHNNGGFIDMDPSMLNVAVSRAKDAFLVFGDLDIIEAAPSSYPRGLLAKYLFTDERNELEFSVGQRPDLLQICGHPKLLTNAEEHDAFLSKLLREVQQKIDIVSPWLLLDKLQSTGQLELLKTALHKGIQITIHTDRHFNTTDANLLNTNKVKAFQHCCATLAQLGIVINVINGVHSKSVFADDRYMAVGSFNWFSASRSRKYANIETSLVYVGELEKEIKIQLDFLNSRSCNTNKQPVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4Y8</accession>
    <name>D0Z4Y8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative inner membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_000221</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell surface</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306645.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000221"/>
    <dbReference type="EnsemblBacteria" id="EEZ39205">
        <property type="protein sequence ID" value="EEZ39205"/>
        <property type="gene ID" value="VDA_000221"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1196">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2169930at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005594">
        <property type="entry name" value="YadA_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03895">
        <property type="entry name" value="YadA_anchor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003020019" evidence="7">
        <location>
            <begin position="22"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="domain" description="YadA_anchor" evidence="8">
        <location>
            <begin position="453"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ39205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="504" mass="55239" checksum="056318836FFD422E" modified="2010-01-19" version="1">MHKFRLSAIVVASVLSTNALAENIDLSGRAQSTGITGRDGRDGRDGRDGQLSTEQLKFINGLNEQIRDGKISTNRQFARTNYIINNLETQIRKNIDSNSSNTTKIATNTTSINGLSERIKTGEALTDKYFAQTHDILDKNLAETANNGRLINNLDLVKADAVSTDARFTETRKNIGSNTTKIATNTKSINGLSERIKAGEALTDKYFAQTHDILDKNLAETANNGRLINNLDLIKADAVSTDARFTEARKNIGSNTTKIATNTKSINSLSERIEAGEALTDTRFTETRKNISSNTTKIATNTKSINSLSERIEAGEALTDTRFTETRKNISSNTTKIATNTKSINGLSERITGEAKSTDIRFAQTYKNIGNNTTKIATNTKNVANNTKAIISNSNTLERYGKQLNEHDEKITFLNNKVDRNTGLIKENTYRINKLEHGMSLMAAMSNLTQDDVTMALGYYNGNTALAMGINYALMPNMNVKFSAAADTEFTQTSLGVGIGYSFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z547</accession>
    <name>D0Z547_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Type II/IV secretion system secretin RcpA/CpaC associated with Flp pilus assembly</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000097</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial secretin family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306838.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000097"/>
    <dbReference type="EnsemblBacteria" id="EEZ39081">
        <property type="protein sequence ID" value="EEZ39081"/>
        <property type="gene ID" value="VDA_000097"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4964">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="870677at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001775">
        <property type="entry name" value="GspD/PilQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032789">
        <property type="entry name" value="T2SS-T3SS_pil_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004846">
        <property type="entry name" value="T2SS/T3SS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00263">
        <property type="entry name" value="Secretin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13629">
        <property type="entry name" value="T2SS-T3SS_pil_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00811">
        <property type="entry name" value="BCTERIALGSPD"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T2SS-T3SS_pil_N" evidence="2">
        <location>
            <begin position="26"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU004003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="442" mass="48724" checksum="3B42AB3AD8E739CC" modified="2010-01-19" version="1">MISKMNKVILFLIISIYSVIASAESLLNLSEGDAATVPVDTEIDSVFISDPAIADYQVIDKNKVVIFGKKIGHTNLFIFDNEGNELANRKVIVNKSLREIKQYISIKFPDANIDIFNFGEQVVLSGTVSNEQVKDEINNIVGTLLSKKSNDFNFNLETDDQDYEVQFMKQKHFTGLVNNIEVLATRQVNVKLSIAEVSHSFLEQIGVQYNSIGHAPGVFVNPLTNFSASDILSVITAIGNDGIGQVLAEPNLSVISGESASFLVGGELPVVTIVDNGTNVTYKEFGVKLELLAKVRKDDKITLSLMPEVSSLDTQYSNDKYDLPALKTRRARTTVELGDGQSFVLGGLLSTEDKERLNKVPYIGDIPVLGALFRNSRTERNKTELIIVATVNLVQPIHPSQVQLPTIRKTTTLDRFFALDSNYESANDKWANEILATGGFKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z564</accession>
    <name>D0Z564_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000114</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306888.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000004.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39098">
        <property type="protein sequence ID" value="EEZ39098"/>
        <property type="gene ID" value="VDA_000114"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5033DZB">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1818983at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="262" mass="29881" checksum="7EA042CDDF23271F" modified="2010-01-19" version="1">MTATVDYIKAKYPKLEFKVTRPPNQRIGLQMENRNLVDSVLVHIGFYKLIGHEHIKRRCDAKSVTCWSYAHGDNASGEIAAQLIQNLGKFKIKTNKLYRSCFEAVANACEHAYTDKVMRDNPFILKRWWFFVGVLNDKITVIICDLGHGIPKTLEVTQDENILTTLWKKLKLPSKPTTDCTLIHASTMVKETRTKEIYRGKGGTDVKTFVDETEQSSLMIFSNKGTYKYEGQNRPSKAYDNSTSVGGTIIQWTIPYTNSEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5E1</accession>
    <name>D0Z5E1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">IncF plasmid conjugative transfer DNA-nicking and unwinding protein TraI</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000048</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000005">
        <property type="protein sequence ID" value="EEZ39063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005307074.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000005.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000048"/>
    <dbReference type="EnsemblBacteria" id="EEZ39063">
        <property type="protein sequence ID" value="EEZ39063"/>
        <property type="gene ID" value="VDA_000048"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0507">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="961809at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014059">
        <property type="entry name" value="Conjug_relaxase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014129">
        <property type="entry name" value="Conjug_relaxase_TraI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040668">
        <property type="entry name" value="TraI_2B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014862">
        <property type="entry name" value="TrwC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18340">
        <property type="entry name" value="TraI_2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08751">
        <property type="entry name" value="TrwC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02686">
        <property type="entry name" value="relax_trwC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02760">
        <property type="entry name" value="TraI_TIGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TrwC" evidence="2">
        <location>
            <begin position="36"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="TraI_2B" evidence="3">
        <location>
            <begin position="696"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF18340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="1980" mass="221608" checksum="70B116931AED0A53" modified="2010-01-19" version="1">MLSLSSLRGGASGASKYYLEEEKQLHLNQPQFTLKTDTQPTKDSPLPPTDNPTANYYLAEQSGTKKTTQWYGKIAEKEGILGHEIEHQKLEAVLNGQLNNDQTPRAHSDTRRTGYDLVFSAPKGASILALVYGDTRIIDAHNAAVKTALDLLEQDTAQAKVTENKEGRFENTQNLLFGLVQHKTNRNNEPQLHTHALQANMTYDNQGNLKNLASSFVQNGFETQGTYERILENAKYYGMAYHSELGRALEGMGFAIKSLGNGQIDIDGIPTEVIEANSTRREEILEYANETGHSSGKSRMIAAHQTRKAKTYTPEDSLVKEWQTKNEALKFDGLAFVAASYNGEHRKDNDISVPDKELQQAIDNSISYLSDRLSAFGYEKVLVTALDKFAPKAITQMGELKQALDNKIKHGDLIALDDKQSLFTTQEQVDREAKLIESTQKRTHGLRVHADSTALNELNLKADTKKTLADILASTKQVNVVNLSGSSKQLSESLLHVSENSGKSIHFITPNKLVKQQTEQQVRRQAFSVTQWVKNAFRPDVVHTAYQYLNQAERRQKTKDSILVVEHANQLGVKETQQLIDLAQRQGNKLVFLNHTKRSQGLRAGNAMDVVQKGNVQTHTWQGAQLAQTHIKTSEVDKKERHQILAERYQELSKQERSETQVLTTNKGDNDNLNRVIRHQLDKSGQLSEKRVEIPTLNPVFMSPEQQRSIKSYQKGMVISQVNDGKVQQYTVEKVNSRAQTLQLLDSDNNRSYLNVKESSTPYFVSQPDKIEVATGDRLRINGDVFRTDLKQNDTVTVEKIGWMGLSLTDDNGKGHLVPLSYLEGSALSYGYANTLNNAAHGKTTTLVEMQSYTASKETLYELMQQGSKQLHIFTDNQEKLEARMEKSHIQPSSMARVMASTQSLDKYVNAQTAETLQSDVTMAVQALLDQQAPKPLIEQAVNFALDHVSEQQAGFKHSELVVEAIRFAMDEKGTTVLESEIHNKLNELQQQDSVLSAQFSDGTRWTTKEAIDTEKRILTRLDAGKGQVASYASERQADAYLAQQDWMTDGQKEAIKLMATTNDRYTIVQGFAGVGKSTMLEQGKTLIEQTQALHGNANIDVLGLAPTHAAVNELKEKGIPAQTTQSLLKDLLTGDTTPDKYKNTLFLLDESSMASNAQFDAFTALVNNSGARATLLGDIYQLQSKEAGKPFELAYRSKSVDTVVMKDIQRQQTPELLSAVQNVINQQSESMLEAIKQQSPLPGSHHNQTVVSTYNETGNSAKDREVAKEELYQSAAAEYLSRTPESRENTLMIAYSNRERDILAGLIRKGLKEMKELLDKSDTPVTRLRGIGTTKEELKTMMPYKAGLIINTGRDTYLHIDSIDRRNELLMVTNMTTGEQTSFIPARHDHKMTTLWSSSEMPLTSGDKITWRKTDKELGLTGNMDLTVSDINKDTIMLSNNDGKHVTLSLSDMKSSHWDYRYTKTADMAQGSTTNHVISVIDSEAKLTNLRRAYIDISRASQHAMIFTDNEKGLMRSWLNHFDNNSSAIETVNKTYHSNERHFDTQSIPRENPKYQQHGEFKLSLYAKDLAQQLTPYTESLAIELLGQPNNSKSDNDYLAFGQGQSHLKVTLTGEYRGYFRDWTTGDKGNLINLIMSAKSFSFKEAVNFAEQILTEPENHNLIENEKHDKLVDTLPKQMSELKERAMSYFEQGAEIKETIANIYINNQTYHDFESHPALRFHEQVYSSETKSTHPALLAALTNNKGEIEAIEITYLNKDGDLADNLTTPKRLMGNKSGHGIVLNDGTLPDISVVAIGLENGISLLGSNTHDVDIVAVTNAHDLRTLDTKALREQIIIMASEHQLSNQNLISDITNKLTAQGHNVSIVKEAMDGLSPQDIGILISDKVNDNIAELKGEHEIDTKKIDQLVDDISKSQEFSNKEIASLLDVIEPKEITHADNVASDKIDNALSEYEHYQEQTAKELEKQIELEKELDYPSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5I3</accession>
    <name>D0Z5I3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000001</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000007">
        <property type="protein sequence ID" value="EEZ38994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005307221.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000007.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ38994">
        <property type="protein sequence ID" value="EEZ38994"/>
        <property type="gene ID" value="VDA_000001"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5032SH3">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1598988at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ38994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="470" mass="54975" checksum="4E4D454A628C7B48" modified="2010-01-19" version="1">MNNKNGVTTFIYRHKNYKNKAQIKRTLQHSLRIENTAYSVGEWNPNLTPKRALLLKPFFNENETHKLSSIKMDDDSLNEREHILNSMIDELFPHEATTKDKQDLTKYKAKLKKKIKETNLEPTLHEILYDTLDNPDESDFTQRINSLSNVKRKKQLLGMLTKYKQLHNLCKSSSDRRASKLHESFFKIPDHNGAVLSPQEIVSTLRSFYKKISPNYDIKLTVFHDDERLETTKEFVGAHVHVFLSCKNNVTQKYDLNKTLKQYVNNHLQLNPINFTDDATGEFIKINNLSSTYRDSKIYGSVMQDLFFNHLQERKPDINFGFTDDRSNRFNQRVDKYIDAKKRKSDRKFNYHNKMIKQYASLQKAITIETENLKKIEAEKNSLVADTSNFVIDIINSINEFINAVHNDGHVDTIKRKRNNIYDLIQEERYSIKIEPAVIMSLLKTIQALASNIKVNVTEFTDAIKNKFTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVJ1</accession>
    <name>D0YVJ1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001571</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298302.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001571"/>
    <dbReference type="EnsemblBacteria" id="EEZ40545">
        <property type="protein sequence ID" value="EEZ40545"/>
        <property type="gene ID" value="VDA_001571"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1266">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1623593at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="178"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="213"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="258"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="283" mass="31278" checksum="3116592BB569C7D3" modified="2010-01-19" version="1">MFIFPSTPELIVWLLLAVSIVTAISSSKPWWSLPLGMTLISALWVGVLTPIGAFVVIIGLAVAYMTQKFSRGYWYIAGHIFVLGWAIALTIHALPGFHNLLVLDKVITSPDSVPFTLYFNLDKPMIVFGLLLLLPNMMGDKPIVWQLTAKQWLGIGVGLVVLPLVAMGVGIVKPDFIVPSWIGWFIFNNLLFTCVAEEVLFRGYIQTQLARKLPIVWAIIFASLLFGIAHIAGGVMLVIVAALAGGLYGLSYYWSKKLTLAIAVHFCFNLIHLLFFTYPLLKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVM3</accession>
    <name>D0YVM3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DNA topoisomerase 3</fullName>
            <ecNumber evidence="6">5.6.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">DNA topoisomerase III</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">topB</name>
        <name evidence="9" type="ORF">VDA_001592</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>ATP-independent breakage of single-stranded DNA, followed by passage and rejoining.</text>
            <dbReference type="EC" id="5.6.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="6">Binds two Mg(2+) per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the type IA topoisomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.1" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298337.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001592"/>
    <dbReference type="EnsemblBacteria" id="EEZ40565">
        <property type="protein sequence ID" value="EEZ40565"/>
        <property type="gene ID" value="VDA_001592"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0550">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="100725at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003917">
        <property type="term" value="F:DNA topoisomerase type I (single strand cut, ATP-independent) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00186">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03362">
        <property type="entry name" value="TOPRIM_TopoIA_TopoIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00953">
        <property type="entry name" value="Topoisom_3_prok"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000380">
        <property type="entry name" value="Topo_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003601">
        <property type="entry name" value="Topo_IA_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023406">
        <property type="entry name" value="Topo_IA_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013497">
        <property type="entry name" value="Topo_IA_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013824">
        <property type="entry name" value="Topo_IA_cen_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013825">
        <property type="entry name" value="Topo_IA_cen_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013826">
        <property type="entry name" value="Topo_IA_cen_sub3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023405">
        <property type="entry name" value="Topo_IA_core_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003602">
        <property type="entry name" value="Topo_IA_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005738">
        <property type="entry name" value="TopoIII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034144">
        <property type="entry name" value="TOPRIM_TopoIII"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11390">
        <property type="entry name" value="PTHR11390"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01131">
        <property type="entry name" value="Topoisom_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01751">
        <property type="entry name" value="Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00417">
        <property type="entry name" value="PRTPISMRASEI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00437">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00436">
        <property type="entry name" value="TOP1Bc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56712">
        <property type="entry name" value="SSF56712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01056">
        <property type="entry name" value="topB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00396">
        <property type="entry name" value="TOPOISOMERASE_I_PROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 6 9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="Toprim" evidence="8">
        <location>
            <begin position="2"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with DNA" evidence="6">
        <location>
            <begin position="195"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="618"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="639"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-tyrosine intermediate" evidence="6">
        <location>
            <position position="328"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="104"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="6">
        <location>
            <position position="62"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="6">
        <location>
            <position position="171"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="6">
        <location>
            <position position="179"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="6">
        <location>
            <position position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ40565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="662" mass="73668" checksum="C3707DE1C9E361B4" modified="2010-01-19" version="1">MSRLYIAEKPSLGRAIATVLPKPHKNNNGYIEVGNGDIVTWCIGHLLEQVEPDAYDERYKKWNLADLPIVPEKWQLIPRKAAKQQLAVIKKLAKSATEIVHAGDPDREGQLLVDEVIDYVKVSQSKKNAAQRLLISDLNPAAVKKALASMRSNKEFIPLSVSALARSRADWLYGMNMTRAYTLLGQKGGYRGVLSVGRVQTPVLGLVTRRDDEIANFIPKPFFEVFALIPYQEQEIRAKWQPSKACEPYQDEDGRILSRPLCENVVKRIKGQPATVIESERKETKQAPPLPYSLSALQIDAAKRYNMSAADVLSTCQSLYEKHKAITYPRSDCRHLPLDHYKQASSVTQAIGTTCPALANGVAQANLSLKSKAWNDKKVDAHHAIIPTPKSVNPQSLNGYEEKIYQLIARQYLMQFYPAAIYAEAKLVFDIANGHFIAKGRQLMSGGWRTLLGRDDATDSDDAGLADKVPPLDKGTVLTCRDGEIKDKMTEPPKAFTEATLLQAMTGIARFVSDASLKKILRDTDGLGTEATRAGILDILFKRQLLHRQGKAIHATDAGRGLIYALPDESTYPDMTAHWEHQLQDMAERNYAYQPFMAALTTQVTQLMEKVKTCEVPESLRSLTSPEPKKGVGKKRNYSRKSGAQTSKSGVTKQRSTRRASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVN2</accession>
    <name>D0YVN2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001197</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297619.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001197"/>
    <dbReference type="EnsemblBacteria" id="EEZ40175">
        <property type="protein sequence ID" value="EEZ40175"/>
        <property type="gene ID" value="VDA_001197"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3391">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="193125at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032295">
        <property type="entry name" value="DUF4842"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045474">
        <property type="entry name" value="GEVED"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031025">
        <property type="entry name" value="LruC_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16130">
        <property type="entry name" value="DUF4842"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20009">
        <property type="entry name" value="GEVED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04456">
        <property type="entry name" value="LruC_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019149" evidence="1">
        <location>
            <begin position="19"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="domain" description="GEVED" evidence="3">
        <location>
            <begin position="337"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4842" evidence="2">
        <location>
            <begin position="461"/>
            <end position="674"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="688" mass="74168" checksum="372025E062CA4671" modified="2010-01-19" version="1">MSKLHIALLFGLGSIAHASYGEAFDSCPSTAFLMQGTPTTVYGVNLTTGSSQTLQTDVGMPGNLNAVGFNETDNYIYAFNTTNKKVVKVDKNFNAQELAVTGIGTQSFYVGDVSNNTLYLYRYGAGLYKVPLDSADPNYLALTAVGGTTNMRIYDFAFHPSDGNIYAVDGKFGTLYQINPATGVRTSLGNTGVKGTFGAAYFESDGMFYLSRNQDGHIFKIDITDPNNIIPIATLFAVGPLSGQNDGVRCASAAAQLDALDLGDAPNTYKTTIASNGPRHDLTNTDYYLGAVPGDAETAPAASDDGDGFDDEDGIIFTSLEKGQTSLIAITASTSGYLNGWIDWNKDGDFADNGEKVFSGTSLSAGMTTAYISVPDYISEGDTWARFRFSSTQNLDYYGGASDGEVEDYPVTLENSNLSTYNYGPYTAAFEDSWPKTGDYDLNDVVVEYNIVVKAAVNYDVKQVQISGSLKAMGADYRNGFAIHLPELARESVDESNIVFVKNGELQTASPLEAGQTNAVLMISPDLYLDIGSDCPYYRTKEDCQEVDLFNFSVTVPLVAGTKLWALPPAPYDPFIFAAEGQYHGDGAVTGRALEIHLDDYEPTDLGSASLTLMGTVNDGSDLASGSAYRASSGLPWGLLISDTWVHPRERTDVLNAYPKFFDYATKGTHNDWFTPGKRVNSFLFAVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVX2</accession>
    <name>D0YVX2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hypothetical LysR-like regular protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001253</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297735.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001253"/>
    <dbReference type="EnsemblBacteria" id="EEZ40231">
        <property type="protein sequence ID" value="EEZ40231"/>
        <property type="gene ID" value="VDA_001253"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1591366at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="9"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="310" mass="35533" checksum="109923144E8473F8" modified="2010-01-19" version="1">MQRINWRGVDLNLLIAFSALMETRSVTKAAQKLSIGQSAMSHNLARLRELLDDPLFERQGHSMLPTQKALELITSVENVLNIITQDILRPDDFEPLDYEGIFKIGLTDYAELLFAPALFDAIHQAAPHCQLSFFNIDRHNYLDRFNQDNLDLVIGSMTQIPKEIEYHHLYTEDHVCLFDQGATQIQPPISIEQYAAIPHALVSPDGQLFTQVDNQLHEQGLKRQIAVGSRNFLTIRHLLSHRRLICVVSRLMAQLDIFNDKLTQCPPPVHIADFDINLLWLRRNAPHPRNSWLRETVTGVITEQVRLLRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW13</accession>
    <name>D0YW13_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phospho-2-dehydro-3-deoxyheptonate aldolase</fullName>
            <ecNumber evidence="5">2.5.1.54</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_001318</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 5">Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14717"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16897"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="2.5.1.54"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 5">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 1/7.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the class-I DAHP synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.54" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297854.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001318"/>
    <dbReference type="EnsemblBacteria" id="EEZ40293">
        <property type="protein sequence ID" value="EEZ40293"/>
        <property type="gene ID" value="VDA_001318"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0722">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="853329at2"/>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00084"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003849">
        <property type="term" value="F:3-deoxy-7-phosphoheptulonate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006218">
        <property type="entry name" value="DAHP1/KDSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006219">
        <property type="entry name" value="DHAP_synth_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21225">
        <property type="entry name" value="PTHR21225"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00793">
        <property type="entry name" value="DAHP_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001361">
        <property type="entry name" value="DAHP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00034">
        <property type="entry name" value="aroFGH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAHP_synth_1" evidence="6">
        <location>
            <begin position="41"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR001361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="355" mass="39084" checksum="2DBA6CE3C9A9010B" modified="2010-01-19" version="1">MHKDQLNNIHIQDESVLITPTQLKSKLPVSASALSFIQQSRQTIANIIHKKDHRLLVVCGPCSIHDVEAAKEYGKKLKALAEELSDQLYIVMRVYFEKPRTTVGWKGLINDPYLDGSFEVEEGLHIARQLLIDLVEMGIPLATEALDPISPQYLGDLFSWAAIGARTTESQTHREMASGLSLPVGFKNGTDGSLATAINAMEAAASGHKFMGINPDGQVALLSTQGNPDGHIILRGGKQTNYDSVSVTECEQEMIASGLSPSLMVDCSHANSRKDFRRQPLVAEDVIHQIREGNRSIIGLMIESHLQEGNQSADLPRADMVYGQSITDACIGWQTTEQLLRHAKQELVPFLQNRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW51</accession>
    <name>D0YW51_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hypothetical transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001333</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001333"/>
    <dbReference type="EnsemblBacteria" id="EEZ40308">
        <property type="protein sequence ID" value="EEZ40308"/>
        <property type="gene ID" value="VDA_001333"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="5"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="297" mass="34295" checksum="34B0399CC4702651" modified="2010-01-19" version="1">MRMNIALKQLNVFVTVAQERTITAAAEKLFLSKPAVSMALSELEKQLDHKLFDRNNNRLIINEQGKRLLPLADELLARSHAIEQLFDQDSIVTGKIRIGSSDTVGNQVTPFLLRDFRQHTDHKEQSLFISNTAQICQKLCEFELDVGLVEGNVQDPELEVIPWLEDEMVIACHPNHPLAQQDHVTLADLENYDWVLRETGSGTREFFLNRVAPRLNKWRPAFELNTTEAIINCIAADLGITCISKRAVKYAEMDYRVHTLSLPLDMHRQYWLLFHKEKYQSPLLTLFIDFCKQWQQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW86</accession>
    <name>D0YW86_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">UDP-3-O-acylglucosamine N-acyltransferase</fullName>
            <ecNumber evidence="6">2.3.1.191</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">lpxD</name>
        <name evidence="8" type="ORF">VDA_001368</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a (3R)-hydroxyacyl-[ACP] + a UDP-3-O-[(3R)-3-hydroxyacyl]-alpha-D-glucosamine = a UDP-2-N,3-O-bis[(3R)-3-hydroxyacyl]-alpha-D-glucosamine + H(+) + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:53836"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="ChEBI" id="CHEBI:137740"/>
            <dbReference type="ChEBI" id="CHEBI:137748"/>
            <dbReference type="EC" id="2.3.1.191"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Bacterial outer membrane biogenesis; LPS lipid A biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homotrimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the transferase hexapeptide repeat family. LpxD subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.191" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297933.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001368"/>
    <dbReference type="EnsemblBacteria" id="EEZ40343">
        <property type="protein sequence ID" value="EEZ40343"/>
        <property type="gene ID" value="VDA_001368"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1044">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1602061at2"/>
    <dbReference type="UniPathway" id="UPA00973"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016410">
        <property type="term" value="F:N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03352">
        <property type="entry name" value="LbH_LpxD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00523">
        <property type="entry name" value="LpxD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007691">
        <property type="entry name" value="LpxD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020573">
        <property type="entry name" value="UDP_GlcNAc_AcTrfase_non-rep"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43378">
        <property type="entry name" value="PTHR43378"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04613">
        <property type="entry name" value="LpxD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01853">
        <property type="entry name" value="lipid_A_lpxD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2 6" id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword evidence="1 6" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5 6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="LpxD" evidence="7">
        <location>
            <begin position="23"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ40343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="342" mass="36160" checksum="A14524031A410B60" modified="2010-01-19" version="1">MAVITLAELAEKLGAELQGDGSVKVSSIANMEKAASGQLTFLSNSKYRKHLADCQASVVILRAGDAEYFAGNKLIVNDPYLAYALTAQELDTTPAAATEIAATAQIASDATLGHGVCIGHNAVIESGVVLGDNVQIGAGCFIGKNAQIGANTKLWANVTIYHEVVLGEQCLVQSNTVIGADGFGYANDKGEWVKIPQLGTVRIGNRVEIGSCTTIDRGALDDTIIEDNVIIDNQMQIAHNVQIGYGTAMAGGTIVAGSTKIGKYCIIGGASVLNGHIEIADGVTITGMGMVMRSIEEKGMYSSGIPLQPNKEWRKTATRVHRIDEMNKRLKAVEKKLEEPSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW94</accession>
    <name>D0YW94_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Type IV pilin PilA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001191</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the N-Me-Phe pilin family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297604.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001191"/>
    <dbReference type="EnsemblBacteria" id="EEZ40169">
        <property type="protein sequence ID" value="EEZ40169"/>
        <property type="gene ID" value="VDA_001191"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4969">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1970253at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009289">
        <property type="term" value="C:pilus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001082">
        <property type="entry name" value="Pilin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00114">
        <property type="entry name" value="Pilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0281">Fimbrium</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0488">Methylation</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="171" mass="17909" checksum="D561BF7CE7B8C32C" modified="2010-01-19" version="1">MKGQKGFTLIELMIVVAIIGILAAFAIPAYQNYTARTHASEMLNASSAFKTSVGVCLLNGNWSTSGSSTTIDCGESKNGVPKQQEFTKNSGDSFTITSDVIAELDNDPNNPGKKIAKYKSGYITAQVKGAKGSLPTDAKVLLKPTITSSGVTWGVTCSTDVGSSTDFCPVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWB0</accession>
    <name>D0YWB0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Prepilin leader peptidase/N-methyltransferase</fullName>
            <ecNumber evidence="10">2.1.1.-</ecNumber>
            <ecNumber evidence="10">3.4.23.43</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">VDA_001188</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>Typically cleaves a -Gly-|-Phe- bond to release an N-terminal, basic peptide of 5-8 residues from type IV prepilin, and then N-methylates the new N-terminal amino group, the methyl donor being S-adenosyl-L-methionine.</text>
            <dbReference type="EC" id="3.4.23.43"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the peptidase A24 family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="10"/>
    <dbReference type="EC" id="3.4.23.43" evidence="10"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297598.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001188"/>
    <dbReference type="MEROPS" id="A24.001"/>
    <dbReference type="EnsemblBacteria" id="EEZ40166">
        <property type="protein sequence ID" value="EEZ40166"/>
        <property type="gene ID" value="VDA_001188"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1989">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2046608at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010627">
        <property type="entry name" value="Pept_A24A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014032">
        <property type="entry name" value="Peptidase_A24A_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000045">
        <property type="entry name" value="Prepilin_IV_endopep_pep"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06750">
        <property type="entry name" value="DiS_P_DiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01478">
        <property type="entry name" value="Peptidase_A24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00864">
        <property type="entry name" value="PREPILNPTASE"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 14" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="10" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="132"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="161"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="185"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="218"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="263"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="DiS_P_DiS" evidence="13">
        <location>
            <begin position="17"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_A24" evidence="12">
        <location>
            <begin position="138"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF06750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEZ40166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="292" mass="32501" checksum="54E671135608F146" modified="2010-01-19" version="1">MAIFSYYPWLFPVFATIFGLLVGSFLNVVIYRLPIMMERQWRNECIEAFPDLIKADAKLNTDTFNLSVPRSRCPHCGHLISAVENIPVISWLALKGKCKSCHAPISRRYPMIELLTAALCGTVAILFPPTWWAVAVIFFTFALIALTFIDIDKMLLPDQITLPLLWAGIFLALLGISPVSLQDSVIGAIAGYLCLWSVFWIFKLLTKKDGMGYGDFKLLAALGAWLGWQMLPVVVLLSSLAGAICGIILLKVQKSDHQTPFSFGPYLAIAGWISLLWGHSIITWYVSNILGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWG6</accession>
    <name>D0YWG6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptidoglycan D,D-transpeptidase MrdA</fullName>
            <ecNumber evidence="3">3.4.16.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Penicillin-binding protein 2</fullName>
            <shortName evidence="3">PBP-2</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">mrdA</name>
        <name evidence="6" type="ORF">VDA_001425</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes cross-linking of the peptidoglycan cell wall.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell inner membrane</location>
            <topology evidence="3">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the transpeptidase family. MrdA subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.4" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298037.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001425"/>
    <dbReference type="EnsemblBacteria" id="EEZ40399">
        <property type="protein sequence ID" value="EEZ40399"/>
        <property type="gene ID" value="VDA_001425"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0768">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="423699at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008658">
        <property type="term" value="F:penicillin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009002">
        <property type="term" value="F:serine-type D-Ala-D-Ala carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02081">
        <property type="entry name" value="MrdA_transpept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005311">
        <property type="entry name" value="PBP_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036138">
        <property type="entry name" value="PBP_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001460">
        <property type="entry name" value="PCN-bd_Tpept"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017790">
        <property type="entry name" value="Penicillin-binding_protein_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03717">
        <property type="entry name" value="PBP_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00905">
        <property type="entry name" value="Transpeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56519">
        <property type="entry name" value="SSF56519"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03423">
        <property type="entry name" value="pbp2_mrdA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="3" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0133">Cell shape</keyword>
    <keyword evidence="3" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="domain" description="PBP_dimer" evidence="5">
        <location>
            <begin position="66"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="Transpeptidase" evidence="4">
        <location>
            <begin position="286"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="3">
        <location>
            <position position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="653" mass="74106" checksum="89D3B4A3F94896CB" modified="2010-01-19" version="1">MRQKRTQIRDHRAESALFFRRALVSFIGIAVLVGVLLTNLYHIQVQEHEDYQTRSNDNRIKIVPVSPNRGLIYDRNGVLLAENRPVYSLEITSEKVPNLEETLLALQEIMGVTEDDITKFQKERRRTRRFKSVPILDQLNEEQVALFSVNQHRFPGVEVKAYLKRHYPYGDALTHVLGYVAKINDRDIKRLEKAEKLSNYKATRDIGKLGIERYYEDQLHGTSGYQEVEVNSRGRVIRTLKYVPPIPGQDLKLNIDIALQLYVQKLLTERSKDPETGEEVVKHKRGSVVVLDPKDDSILAMVSSPSYDPNLFVKGISGKNYRELLNNPDRPLVNRVTLGIYPPASTVKPLIAVAALTEGVVTTKTTRNDPGWWVIPNSTSRKFRDWLRWGHGSVNIYKAIEESVDTYFYQVAYDMGIDRLSTWMNKFGYGEYTGVDIHEESKANMPTREWKQARYRQPWYQGDTIPVGIGQGYWTATPLQIAKATSVLVNNGVVHRPHLLQSTIEDGVETKTEFKDFPPITGVKQSTWDVAKEGMHRVLYGHRGTARKAFYHTPYQAGGKSGSAQVFGLAENQKYNADELEERLRDHALFTAFAPFEDPKVVVSMVLENAGGGSSNGGPIARKIFDHMLLEPSAVNDLSKTENNKTASTEETQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWK1</accession>
    <name>D0YWK1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosome-binding ATPase YchF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ychF</name>
        <name evidence="7" type="ORF">VDA_001440</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298067.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001440"/>
    <dbReference type="EnsemblBacteria" id="EEZ40414">
        <property type="protein sequence ID" value="EEZ40414"/>
        <property type="gene ID" value="VDA_001440"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0012">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="603226at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04867">
        <property type="entry name" value="TGS_YchF_OLA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01900">
        <property type="entry name" value="YchF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00944">
        <property type="entry name" value="YchF_OLA1_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004396">
        <property type="entry name" value="ATPase_YchF/OLA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023192">
        <property type="entry name" value="TGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013029">
        <property type="entry name" value="YchF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041706">
        <property type="entry name" value="YchF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06071">
        <property type="entry name" value="YchF-GTPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006641">
        <property type="entry name" value="CHP00092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="SSF81271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00092">
        <property type="entry name" value="TIGR00092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OBG-type G" evidence="5">
        <location>
            <begin position="3"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="TGS" evidence="6">
        <location>
            <begin position="278"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="12"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="363" mass="39716" checksum="6DB91644659F44D7" modified="2010-01-19" version="1">MGFKCGIVGLPNVGKSTLFNALTKAGIEAANFPFCTIEPNTGVVPVPDPRMDALAVFVKPERILPTTMEFVDIAGLVAGASKGEGLGNKFLANIRETDAIGHVVRCFENENIVHVAGRIDPLEDMDIINLELAMADLDTCERALQRLAKRAKGGDNEAKFEIKVLEKMLPHLTEGGMLRSLELTKEEKVAIDYLHFLTLKPTMYIANVNEDGFENNPFLDAVMERAAQENAVVVPVCAAIESEIAELDDADREEFLADLGIEEPGLNRVIRSGYELLSLQTYFTAGVKEVRAWTIPVGATAPKAAGVIHTDFEKGFIRAEVIGYDDYIECGGEAGAKEAGKWRLEGKEYIVKDGDVVHFRFNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWM6</accession>
    <name>D0YWM6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001517</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001517"/>
    <dbReference type="EnsemblBacteria" id="EEZ40491">
        <property type="protein sequence ID" value="EEZ40491"/>
        <property type="gene ID" value="VDA_001517"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="433" mass="50638" checksum="6C64E1408B3AFBCC" modified="2010-01-19" version="1">MLFKWISSKEKNIMNSIVFVCNYFPPEEHVGVRRVSFWVNYFSGLGYKVTVVTTSKKQSEKLYHFIDKRVNVYEYGYFKINKVPFVEVDRDNNNLVVQETNFVSKLKKIKRKYINPIFGQVLDFRIIPIIFQMVKIKFGGDKEIINEIFRNSVVISTSPPWVSHIFAIFLSKRSQSKLIIDYRDPFSNNYMFSSKFCWLETFIDKYICRSADVVTTVSESWLNYYKEFNDNTILIRNGFDLNMFEKDVPITIKSDRIINLSYFGSIEHPLRIPRTLMDFLEKTKKNIKINFYGSCSLIEDIVNRSSSLSDKVILHGPKSYDECIRIMKSSEINFVSESVVFNTWSSRGLIPTKIYEYIASGRPIIAELDPYSDAAKILRQSGLLLAPILVDPDYEKIFDDLDLNNFKIKKDNNFIYSLSRQSSTNILEKIINE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWQ0</accession>
    <name>D0YWQ0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptide chain release factor 1</fullName>
            <shortName evidence="5">RF-1</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">prfA</name>
        <name evidence="9" type="ORF">VDA_001446</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 5">Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="5">Methylated by PrmC. Methylation increases the termination efficiency of RF1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the prokaryotic/mitochondrial release factor family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298075.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001446"/>
    <dbReference type="EnsemblBacteria" id="EEZ40420">
        <property type="protein sequence ID" value="EEZ40420"/>
        <property type="gene ID" value="VDA_001446"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0216">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="928964at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016149">
        <property type="term" value="F:translation release factor activity, codon specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00093">
        <property type="entry name" value="Rel_fac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005139">
        <property type="entry name" value="PCRF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000352">
        <property type="entry name" value="Pep_chain_release_fac_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045853">
        <property type="entry name" value="Pep_chain_release_fac_I_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004373">
        <property type="entry name" value="RF-1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03462">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00472">
        <property type="entry name" value="RF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00937">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75620">
        <property type="entry name" value="SSF75620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00019">
        <property type="entry name" value="prfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00745">
        <property type="entry name" value="RF_PROK_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0488">Methylation</keyword>
    <keyword evidence="4 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RF_PROK_I" evidence="8">
        <location>
            <begin position="230"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="286"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="55"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="modified residue" description="N5-methylglutamine" evidence="5">
        <location>
            <position position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ40420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="362" mass="40630" checksum="AA59C86BD50B713B" modified="2010-01-19" version="1">MKPSILVKLETLEERYEEVQHLLGDPSVISDQDKFRSLSKEYSQLEEVTKCFQAYKQAQDDLAAAEEMANEDDAEMREMAQEEIKEAKAEIERLEDELQVLLIPKDPNDERNCFLEIRAGAGGDEAGIFAGDLFRMYSRYAERRGWRIEVMSANDAEHGGYKEMIAKVTGDGAYGVLKFESGGHRVQRVPATESQGRVHTSACTVAVLPEIPEAEIPEINPSDLKIDTYRSSGAGGQHVNTTDSAIRITHLPTGIVVECQDERSQHKNKAKAMSVLAARIIKAEEEKRHAEEASTRRNLLGSGDRSDRIRTYNYPQGRVSDHRITLTIYRLNEVMEGDVDCLIQPVLVEYQADQLAAMAEQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWZ1</accession>
    <name>D0YWZ1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative phage protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002044</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299260.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002044"/>
    <dbReference type="EnsemblBacteria" id="EEZ41012">
        <property type="protein sequence ID" value="EEZ41012"/>
        <property type="gene ID" value="VDA_002044"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1196">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="886955at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="561" mass="65845" checksum="1371DFF7D6208D49" modified="2010-01-19" version="1">MKKIVFQQLSLISDLEKSANIFQFSQKKNLILGSKNNVGKTCLSTSIFWALGIDLKQPKSWKDLGVRTVIKFTVGCDTYHISRKEKSFVIHYPNYNKSYFDSLKSFSIAFANIINFKACIKEKSASSPTVPYTAIQLICSYIHQDTGWSELFKSFNLYYYHKNEISKAIDYFVGLKPDEYFKPQLEELPITREITKLTQKIDNISFTKEAISVFNKDNTELFNPFENYKHIKENKQLNALLYNETEIKELLLIQKKERFALKEEIKIIESACTELFKDYQFATNNIEDQIIQCPTCGTEHENNVVARFNIIDDRDKLITCKTNALNQLYILNEEIDNNKRRLNLIKNEILMFERFHNLPSLIEDKLLNDNINIFDNAIKLTFDKIIASSKLEIDTLKTKKESIKKFSNNKEQKERYKNIVNEFNDKLLTNFKKLNIEDAQVLYDKKIIYSFDVSGSDISRSILSYYKTLNDMMKEHCSVYSLPFVIDTPYQQEQDNINIDYINNFLNDWDEQQLLIFGVNNKNYQSLIDNKDSNVIMLTNKKSLLSVDMYNKITQEFNIYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX81</accession>
    <name>D0YX81_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Phosphotransferase system fructose-specific IIB and IIC subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">VDA_001940</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001940"/>
    <dbReference type="EnsemblBacteria" id="EEZ40908">
        <property type="protein sequence ID" value="EEZ40908"/>
        <property type="gene ID" value="VDA_001940"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1299">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1445">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022877">
        <property type="term" value="F:protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05569">
        <property type="entry name" value="PTS_IIB_fructose"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036095">
        <property type="entry name" value="PTS_EIIB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013011">
        <property type="entry name" value="PTS_EIIB_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003501">
        <property type="entry name" value="PTS_EIIB_2/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003352">
        <property type="entry name" value="PTS_EIIC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013014">
        <property type="entry name" value="PTS_EIIC_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003353">
        <property type="entry name" value="PTS_IIB_fruc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006327">
        <property type="entry name" value="PTS_IIC_fruc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02378">
        <property type="entry name" value="PTS_EIIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02302">
        <property type="entry name" value="PTS_IIB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52794">
        <property type="entry name" value="SSF52794"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00829">
        <property type="entry name" value="FRU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01427">
        <property type="entry name" value="PTS_IIC_fructo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51099">
        <property type="entry name" value="PTS_EIIB_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51104">
        <property type="entry name" value="PTS_EIIC_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-0598">Phosphotransferase system</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="7 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="222"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="250"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="288"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="333"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="374"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="412"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="473"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="515"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="domain" description="PTS EIIB type-2" evidence="13">
        <location>
            <begin position="93"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="PTS EIIC type-2" evidence="14">
        <location>
            <begin position="211"/>
            <end position="546"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEZ40908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="548" mass="56688" checksum="76BBACE03ED84FD9" modified="2010-01-19" version="1">MGWEAAIECQSSVVDGKTLTVDEINQADCIVVATSKTLDLQRFVGKKVYVADIADCFENTKTFLEQAVAKAQTLDKVTAPSIVEQPTSGTKRIVAITACPTGVAHTFMAAEALEEEGQRQGYEIKVETRGSVGAKNQLTADEIAAADLVIIAADIEVDLSRFAGKKLYKTSTGAALKKTKEEFAKAFATATTYQQDAANSTAETKEEKTGAYKHLMTGVSHMLPLVVAGGLSIALSFVFGIEAFKQEGTLAAALMTIGGGSAFALMVPVLAGFIAFSIADRPGLAPGLIGGMLASSTGAGFLGGIVAGFLAGYSAKFLANNVKLPQSMEALKPILIIPLVSSLFTGLVMIYVVGGPVSAAMTGLTEFLNNMGSANAVLLGIILGCMMCFDLGGPVNKAAYTFGVGLLASQTYAPMAAVMAAGMVPAMGMGLATFLAKRKFNQNEQEAGKASFVLGLCFISEGAIPFAAKDPMRVIPCCMAGGALTGALSMLFGAKLMAPHGGLFVLLIPNAITPVLGYLIAIAAGTILTGIAYAFVKKTDQELVSAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXA7</accession>
    <name>D0YXA7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cold shock-like protein CspD</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001647</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298437.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001647"/>
    <dbReference type="EnsemblBacteria" id="EEZ40620">
        <property type="protein sequence ID" value="EEZ40620"/>
        <property type="gene ID" value="VDA_001647"/>
    </dbReference>
    <dbReference type="GeneID" id="57342271"/>
    <dbReference type="eggNOG" id="COG1278">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2034748at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04458">
        <property type="entry name" value="CSP_CDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012156">
        <property type="entry name" value="Cold_shock_CspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011129">
        <property type="entry name" value="CSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019844">
        <property type="entry name" value="CSD_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002059">
        <property type="entry name" value="CSP_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012751">
        <property type="entry name" value="CspD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00313">
        <property type="entry name" value="CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002599">
        <property type="entry name" value="Cold_shock_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00050">
        <property type="entry name" value="COLDSHOCK"/>
    </dbReference>
    <dbReference type="SMART" id="SM00357">
        <property type="entry name" value="CSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02381">
        <property type="entry name" value="cspD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00352">
        <property type="entry name" value="CSD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51857">
        <property type="entry name" value="CSD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CSD" evidence="4">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="73" mass="8084" checksum="AF4DA5F8C4487256" modified="2010-01-19" version="1">MAIGTVKWFNNAKGFGFICPEDGDGDIFAHYSTIQMDGYRTLKAGQQVNYEVQTGPKGFHAREITPIESNDAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXD6</accession>
    <name>D0YXD6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ion-translocating oxidoreductase complex subunit E</fullName>
            <ecNumber evidence="9">7.-.-.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Rnf electron transport complex subunit E</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">rnfE</name>
        <name evidence="10" type="ORF">VDA_001615</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Cell inner membrane</location>
            <topology evidence="2 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the NqrDE/RnfAE family.</text>
    </comment>
    <dbReference type="EC" id="7.-.-.-" evidence="9"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298382.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001615"/>
    <dbReference type="EnsemblBacteria" id="EEZ40588">
        <property type="protein sequence ID" value="EEZ40588"/>
        <property type="gene ID" value="VDA_001615"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4660">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1782047at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022900">
        <property type="term" value="P:electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00478">
        <property type="entry name" value="RsxE_RnfE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003667">
        <property type="entry name" value="NqrDE/RnfAE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010968">
        <property type="entry name" value="RnfE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30586:SF0">
        <property type="entry name" value="PTHR30586:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02508">
        <property type="entry name" value="Rnf-Nqr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006102">
        <property type="entry name" value="NQR_DE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01948">
        <property type="entry name" value="rnfE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="98"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="127"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="182"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ40588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="228" mass="24472" checksum="C343D3D9BB63987F" modified="2010-01-19" version="1">MSTNTELMKNGLWYNNPTVVQLLGLCPLLAVSATVTNALGLGLATTMVLVGSNLIVSLIRNVVPSEIRIPVFVMIIAALVTCVQLLMNAYTYGLYKSLGIFIALIVTNCIIIGRAESFASKNKPLPAVLDGLWMGLGMTSALVILGAMRELLSKGTLFDGADRLLGSWASSLRIEVFHYDNGFLLAMLPPGAFFGVGLMIALKNVIDKKQQDKKNAVEQQAKAVSTPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXL2</accession>
    <name>D0YXL2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001727</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298585.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001727"/>
    <dbReference type="EnsemblBacteria" id="EEZ40697">
        <property type="protein sequence ID" value="EEZ40697"/>
        <property type="gene ID" value="VDA_001727"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2200">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="19"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="3">
        <location>
            <begin position="152"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="414" mass="46707" checksum="855C01D86FA0214D" modified="2010-01-19" version="1">MTEIKSTQCQTSTLPMDKKILVLEDHAFQRWFLVNSIKQLGYQSVLEAASGQEALAICQQQAIDIILCDLELPDMDGIEVLRKLSEQKKALSIILCSAVDESVLCTVSKMVEASNLVLLGQATKPIEKDHLSQLLNKSVCFSCASSQQNPGFQPSLIDIQQALENKEFSVHYQPKVCLDNGQWTGIEAFIRWPHPVYGMIAPNRFIPIAEQDDIINALFLYIADQAITDLANLHKQGWQGTVAINLAAKNLVHFETMQAMVNLVADSEVNSKDIVLELTERQALPAQAERSLEAMARLNMKGFKLSLDDFGTGFSSLQQLDYFPFSEVKLDRSFVDNCQSSIFNQTVIEFCMTLAKRLNLNVVFEGIEDIETLNFLRTFQYGSAQGFFIAKPMPYEQLLEWHQQWQLQNPIQDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXL8</accession>
    <name>D0YXL8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">UPF0313 protein VDA_001759</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_001759</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="6">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the UPF0313 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298642.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001759"/>
    <dbReference type="EnsemblBacteria" id="EEZ40727">
        <property type="protein sequence ID" value="EEZ40727"/>
        <property type="gene ID" value="VDA_001759"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1032">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="229299at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01251">
        <property type="entry name" value="UPF0313"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020612">
        <property type="entry name" value="Methylthiotransferase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022946">
        <property type="entry name" value="UPF0313"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024560">
        <property type="entry name" value="UPF0313_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013704">
        <property type="entry name" value="UPF0313_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32331">
        <property type="entry name" value="PTHR32331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11842">
        <property type="entry name" value="DUF3362"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08497">
        <property type="entry name" value="Radical_SAM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01069">
        <property type="entry name" value="UPF0313"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03904">
        <property type="entry name" value="SAM_YgiQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01278">
        <property type="entry name" value="MTTASE_RADICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4 6" id="KW-0408">Iron</keyword>
    <keyword evidence="5 6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="8">
        <location>
            <begin position="363"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="681"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="696"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="714"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="377"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="381"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="384"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ40727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="799" mass="89558" checksum="2DD93CEA8A5052C3" modified="2010-01-19" version="1">MNLTKINEYPKYWAECYGTAPFLPTTRKEMDELGWDSCDIIIVTGDAYVDHPSFGMAIIGRLLESQGFRVGIIPQPKWDNKDAFMELGKPNLFFGVTAGNMDSMINRYTADRKLRHDDAYTPNNEGGKRPDRAVLVYSQRCREAYKEAPIVLGGIEASLRRLAHYDYWSDKVRRSVLMDAKADILLFGNAERALVEVAHRIANGENVKEMINIPGTAVMLKELPEGFSEIDSSRIEKPGRPMVMPNPYATEETCANNKAEQQETPAQVVTVQPSRHDSKHTAVRLPSYEKLQNDRILYAHASRVMHLETNPYSGRALIQKHADRELWVNRSPTPLTTEEMDFVFGLPYARIPHPRYGKAKIPAYDMIKTSVNIMRGCFGGCSFCSITEHEGRIIQNRSKESILNELEEIRDKVPGFTGTISDLGGPTANMYRLGCSDPRAEANCRRPSCIFPEICKKLNTDHKHTIDLYRQARNLKGIKKILIASGVRYDLAVESPEYVRELVTHHVGGYLKIAPEHTEKGTLDLMMKPGMGTYYRFKEMFEKYSKEAGKKQYLIPYFISAHPGSTDDDMLNLALWLKENNFECDQVQNFYPSPMCNATTMYHSETNPLKKVKYKGRDDLFVAKGERQRRLHKALLRYHDPANWALIRQALVSMGKKHLIGNRPGCLVPPEGAEDSVTTLAQKRGSGRHAAKRFATKHPNQPDIRKDGKRGNGGNGANNGNGNGNGNGNGNGNGNGNGNGNNNRPGQRDNQNRNGRPNNGNNKPAGNRNGNKPAQGQGRNKPAGQKPTSKFSGKPKNKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXR0</accession>
    <name>D0YXR0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UPF0265 protein VDA_002073</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002073</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the UPF0265 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299351.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002073"/>
    <dbReference type="EnsemblBacteria" id="EEZ41041">
        <property type="protein sequence ID" value="EEZ41041"/>
        <property type="gene ID" value="VDA_002073"/>
    </dbReference>
    <dbReference type="GeneID" id="57341816"/>
    <dbReference type="eggNOG" id="COG2926">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1885745at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00683">
        <property type="entry name" value="UPF0265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007458">
        <property type="entry name" value="DUF496"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39591">
        <property type="entry name" value="PTHR39591"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04363">
        <property type="entry name" value="DUF496"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028773">
        <property type="entry name" value="UCP028773"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="106" mass="12797" checksum="545240496393E0C8" modified="2010-01-19" version="1">MNNILELVRETRRKNKLKREILDNDRKIRDNRKRVELLENLLDYIKADMSHDQIVEIVENMKSDYEDRVDDHIIISAELSKERRDVSKHVKELKKAEIAHKPENHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXS1</accession>
    <name>D0YXS1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ribosomal RNA large subunit methyltransferase K/L</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="5">23S rRNA m2G2445 methyltransferase</fullName>
                <ecNumber evidence="5">2.1.1.173</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="5">rRNA (guanine-N(2)-)-methyltransferase RlmL</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="5">23S rRNA m7G2069 methyltransferase</fullName>
                <ecNumber evidence="5">2.1.1.264</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="5">rRNA (guanine-N(7)-)-methyltransferase RlmK</fullName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="5" type="primary">rlmL</name>
        <name evidence="8" type="ORF">VDA_002084</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>guanosine(2069) in 23S rRNA + S-adenosyl-L-methionine = H(+) + N(2)-methylguanosine(2069) in 23S rRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:43772"/>
            <dbReference type="Rhea" id="RHEA-COMP:10688"/>
            <dbReference type="Rhea" id="RHEA-COMP:10689"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74481"/>
            <dbReference type="EC" id="2.1.1.264"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>guanosine(2445) in 23S rRNA + S-adenosyl-L-methionine = H(+) + N(2)-methylguanosine(2445) in 23S rRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42740"/>
            <dbReference type="Rhea" id="RHEA-COMP:10215"/>
            <dbReference type="Rhea" id="RHEA-COMP:10216"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74481"/>
            <dbReference type="EC" id="2.1.1.173"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the methyltransferase superfamily. RlmKL family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.173" evidence="5"/>
    <dbReference type="EC" id="2.1.1.264" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002084"/>
    <dbReference type="EnsemblBacteria" id="EEZ41052">
        <property type="protein sequence ID" value="EEZ41052"/>
        <property type="gene ID" value="VDA_002084"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0116">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1092">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052915">
        <property type="term" value="F:23S rRNA (guanine(2445)-N(2))-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070043">
        <property type="term" value="F:rRNA (guanine-N7-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01858">
        <property type="entry name" value="23SrRNA_methyltr_KL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017244">
        <property type="entry name" value="23SrRNA_methyltr_KL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000241">
        <property type="entry name" value="RNA_methylase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019614">
        <property type="entry name" value="SAM-dep_methyl-trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004114">
        <property type="entry name" value="THUMP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10672">
        <property type="entry name" value="Methyltrans_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02926">
        <property type="entry name" value="THUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01170">
        <property type="entry name" value="UPF0020"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037618">
        <property type="entry name" value="RNA_Mtase_bacteria_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00981">
        <property type="entry name" value="THUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51165">
        <property type="entry name" value="THUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01261">
        <property type="entry name" value="UPF0020"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 5 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="3 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="THUMP" evidence="7">
        <location>
            <begin position="9"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ41052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="680" mass="77308" checksum="3618E9B218D9D609" modified="2010-01-19" version="1">MRFKATQAEAYRCCLWTRISSRIIYVLSEFNVRNDLDLYLGATAINWNNYFGSNTRIVVDFNGTNREIRNSQYGAMKVKDAIVDRFTKMDLMRPSIDRERPDLRIHVRLSGEKAILGLDMAGSGLHQRGYRSEAGKAPLRETHAAALVMKSGWTFEQPLLDPMCGSGTLVIEAAMIAAEIAPGIKRKRWGFEALKDFDKEAWLEIHAEAKVKARRGPAKAKEIVKIYGRELDQRVLAIARDNAGRAGVSELIDFERGDAMHLMAPEGFSDGVILCNPPYGERLGTTPELIALYTEFGQRLKLAFTGSRAAIYSASNELLSCMRMRADKQFKLRNGALDCVLKTYLITGGSVKKEEGQSEGVVEETEIAPDFANRLKKNITKLSKWAKREGIECYRLYDADLPNYNAAIDQYKDYIVIQEYAAPKTIPEEVARRRLMDIMRATIAVTGVDNSKVILKVRERQKGKNQYQKLSSVERFMTVSEYDVKLKVNLYDYLDTGVFLDHRITRRKLGSMAKGKDFLNLFSYTGSATVHAACGGAKSTTTVDMSNTYLEWAKDNMKLNGQVGRQHNYIQADCLQWLQESNESFDLIFIDPPTFSNSKRMKQTFDVQRDHIMLMENLKRMLRPEGQIVFSNNKRQFKMDLEALAELGLQAKNISDKTLPMDFAKNKQIHNCWIITHKED</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXV2</accession>
    <name>D0YXV2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Spermidine putrescine ABC transporter permease component PotB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_002115</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299479.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002115"/>
    <dbReference type="EnsemblBacteria" id="EEZ41083">
        <property type="protein sequence ID" value="EEZ41083"/>
        <property type="gene ID" value="VDA_002115"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1176">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1488093at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="69"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="151"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="198"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="252"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="65"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="285" mass="32339" checksum="CEDC3808A638C393" modified="2010-01-19" version="1">MSKKFNLQNIIISIIVGWLVVFVFMPNLMIIGTSFLTRDDANLIKMVFTLDNYTRLFDPLYAKVMWHSFYMALTATILCLLIGYPFAYAIAKMPEKWRPFMLFLVIVPFWTNSLIRTYGLKIMLGTRGLLNNTLMYLDIIDKPLRIMYTEYAVMIGLVYILLPFMVLPLYSAIEKLDNTYIEAARDLGANKFQTFTKVIFPLTMPGIIAGCLLVLLPALGMFYVSDLLGGAKNLLIGNVIKSQVLNARDWPFGAATSIALTVAMAVLLYAYYRAGKLLNRKVDLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-08-12" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXW6</accession>
    <name>D0YXW6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Sulfur carrier protein FdhD</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">fdhD</name>
        <name evidence="5" type="ORF">VDA_002129</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FdhD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299503.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002129"/>
    <dbReference type="EnsemblBacteria" id="EEZ41097">
        <property type="protein sequence ID" value="EEZ41097"/>
        <property type="gene ID" value="VDA_002129"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1526">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="948173at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097163">
        <property type="term" value="F:sulfur carrier activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016783">
        <property type="term" value="F:sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00187">
        <property type="entry name" value="FdhD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003786">
        <property type="entry name" value="FdhD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30592">
        <property type="entry name" value="PTHR30592"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02634">
        <property type="entry name" value="FdhD-NarQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015626">
        <property type="entry name" value="FdhD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00129">
        <property type="entry name" value="fdhD_narQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="278"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine persulfide intermediate" evidence="3">
        <location>
            <position position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="298" mass="32817" checksum="8CD7313AC71B787D" modified="2010-01-19" version="1">MTQLPKIIKTNSSVKQTFTVDIMDEYGDMQTKEIACEHPLTVYLNWIEIVTLMTLGERPSALVLGYLKNQGFIKDIDAIESVIIDWDTNSAAVITKENTDGVSKTLEKKTVTSGCGQGTMYGNVMKKLEGVTLPQPQISQAKLYQLLEALTHHNETYKAAGAVHGCAVCKDTEILSFVEDVGRHNAVDTLAGEMWLKGETGNDKIFYTTGRLTSEMVIKVAQMGIPVLLSRSGATQMGYELAQKLGITMIARAKGHRFQVYSGMDNLILDVKGNAMSDTEQKQQEKMTPNKGQSDNLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY05</accession>
    <name>D0YY05_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Phosphotransferase system N-acetylglucosamine-specific IIBC component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">VDA_002168</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002168"/>
    <dbReference type="EnsemblBacteria" id="EEZ41136">
        <property type="protein sequence ID" value="EEZ41136"/>
        <property type="gene ID" value="VDA_002168"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1263">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1264">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019866">
        <property type="term" value="C:organelle inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015572">
        <property type="term" value="F:N-acetylglucosamine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008982">
        <property type="term" value="F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00212">
        <property type="entry name" value="PTS_IIB_glc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036878">
        <property type="entry name" value="Glu_permease_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018113">
        <property type="entry name" value="PTrfase_EIIB_Cys"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003352">
        <property type="entry name" value="PTS_EIIC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013013">
        <property type="entry name" value="PTS_EIIC_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001996">
        <property type="entry name" value="PTS_IIB_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010974">
        <property type="entry name" value="PTS_IIBC_nag"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00367">
        <property type="entry name" value="PTS_EIIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02378">
        <property type="entry name" value="PTS_EIIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55604">
        <property type="entry name" value="SSF55604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00826">
        <property type="entry name" value="EIIB_glc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01998">
        <property type="entry name" value="PTS-II-BC-nag"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51098">
        <property type="entry name" value="PTS_EIIB_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01035">
        <property type="entry name" value="PTS_EIIB_TYPE_1_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51103">
        <property type="entry name" value="PTS_EIIC_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0598">Phosphotransferase system</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="5 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="82"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="118"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="210"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="240"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="263"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="317"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="domain" description="PTS EIIC type-1" evidence="14">
        <location>
            <begin position="1"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="domain" description="PTS EIIB type-1" evidence="13">
        <location>
            <begin position="366"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphocysteine intermediate; for EIIB activity" evidence="11">
        <location>
            <position position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEZ41136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="441" mass="46993" checksum="647E6926376B12A7" modified="2010-01-19" version="1">MFPIAVLPVAGMLLRFGQPDLLNIPFMAAGGQAVFDNLALLFAMGVAGGFSKDNSAAAAIAACVGYFIMTSALKTLNADVDPGVAGGIIIGLCAGHLYNRFNGIKLPEFLGFFAGKRFVPIITGLVALIIAYIFSLVWPPVQEMINHLGQWILTSGKPGEFAYGLANRLLIPIGLHHILNTMVWFVFGDYHGATGEISRFFAGDPNAGQILSGFFPVVMFGLPSAALAFYVTAKKENKKVVGGMLLSVALTAFLTGITEPIEFMFMFLTPGLYLIHAILMGVSLVVASSLNIHMAFSFSSGLIDYMLNFNAPAAHNAWMIIPLGIATGVIYFVLFVAAIKFFNLKTPGREDAPAENANPAKAENNTELAKAYLEALGGKENLTDIAACITRLRLGIVDRSVIDDAKLKQLGAKGVVNVGSNNLQVILGPLAEKIATEMNSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY13</accession>
    <name>D0YY13_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002176</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299594.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41144">
        <property type="protein sequence ID" value="EEZ41144"/>
        <property type="gene ID" value="VDA_002176"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG503108C">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1521818at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="181" mass="21082" checksum="4F40587F88EF0AD8" modified="2010-01-19" version="1">MFTFLRKLMQGITHSNHSKALDLSIYNNTYPKVTQSKEMNEQAYNLLFLIDTESTDLLVQLIQRHAGIRITLNDTKEPQDFSSKQVILKLNVFSDFNGHIVHLITDQTDLVSGIINSNFHPPKPEHSFPDISPLEYGSLQGNLDFWFNWLWLPYWQNLSKEEQKELAITADWVEFIEEQIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY99</accession>
    <name>D0YY99_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein-tyrosine-phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_002262</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10684"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:10137"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:82620"/>
            <dbReference type="EC" id="3.1.3.48"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002262"/>
    <dbReference type="EnsemblBacteria" id="EEZ41230">
        <property type="protein sequence ID" value="EEZ41230"/>
        <property type="gene ID" value="VDA_002262"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0394">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023485">
        <property type="entry name" value="Ptyr_pPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036196">
        <property type="entry name" value="Ptyr_pPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01022">
        <property type="entry name" value="HTH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01451">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00226">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52788">
        <property type="entry name" value="SSF52788"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="4">
        <location>
            <begin position="112"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="226" mass="25710" checksum="A5CB32299EB9089C" modified="2010-01-19" version="1">MCREQNITYQVASAGVKPEGVDHRVAIVLAENGIDSDDLISQSVDEYQDQHFDVVITLCDKANNECAFFDDSEAFIHWDFKDPKSEEGIDGFRRVFNELKGRIALFLLLNGEDSSDVLGPVELFKVMSDPLRLRILMLLVDEKALSVSDLTSVLEVSQPKVSRHLALLRDSGILQIERQGLWIFYQLSNQLPIWIKHTLDTVRTGNPDIINHEKKLLRHLGIKKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYC0</accession>
    <name>D0YYC0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002283</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41251">
        <property type="protein sequence ID" value="EEZ41251"/>
        <property type="gene ID" value="VDA_002283"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="245" mass="28305" checksum="E0264C8FD72D27CA" modified="2010-01-19" version="1">MKKLVSRYSLHICFCFAGFYISAVSLAYADAESHSFVSVLNSIGVFLASAGAVAALLTLFHVVYSRVEDKEEQEVNYFKYSLFILDRQAMFISMYEHRIAHFQKVDETQRALQLESIKFDDTLCNAISIERSLGLLSSPNAALLSELDRCQRDFKILSNTIAQRNQLYINDYQRKVQHHFSLGMAFSQEELEEIVGNSLLPSLVEFTNEIYLQLPKVKGHIVDVHKQLYTEFKRKYPYRKFVESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYH4</accession>
    <name>D0YYH4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002337</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002337"/>
    <dbReference type="EnsemblBacteria" id="EEZ41305">
        <property type="protein sequence ID" value="EEZ41305"/>
        <property type="gene ID" value="VDA_002337"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502ZCJH">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021431">
        <property type="entry name" value="DUF3080"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11279">
        <property type="entry name" value="DUF3080"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="360" mass="42542" checksum="7D5C979C9DAA4957" modified="2010-01-19" version="1">MCNPLRYLSFSVWFLLIVILNGCDTLSSSDSPFHIYAQRLANVLDTSFDERTVNTYLDIIPYPDNRDIYQTIPDIRIGLLDAYELRQCGLFHLIAERNSVLGKVQDKTRQLRYEILFLQGLRTCLATLDTKTDLYQQLVSIEQQKQQQIPQYLWNMLFTGEEWRKQFVINYQWINSKQQNGFHSFLDAVRLVNYLSQSTEQQAIIPSNQLDLLLQSQAELYKNPYFGRLLYSIAQSTAWLNAITHMLKDHQESIYCGPSRNNQKAQYLNNVFYKYYSQDIQSYLATLSSQYQQLQPLLLELYQHSLRHGITPSPQMSRYSQYYFANHLYRNFKQATLEHVEYWKTLFKRCNFPVGNNQAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYI2</accession>
    <name>D0YYI2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8">Ribokinase</fullName>
            <shortName evidence="8">RK</shortName>
            <ecNumber evidence="2 8">2.7.1.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rbsK</name>
        <name evidence="10" type="ORF">VDA_002345</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + D-ribose = ADP + D-ribose 5-phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13697"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:47013"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.15"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="8">Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.</text>
    </comment>
    <comment type="activity regulation">
        <text evidence="8">Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8">Carbohydrate metabolism; D-ribose degradation; D-ribose 5-phosphate from beta-D-ribopyranose: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.15" evidence="2 8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299927.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002345"/>
    <dbReference type="EnsemblBacteria" id="EEZ41313">
        <property type="protein sequence ID" value="EEZ41313"/>
        <property type="gene ID" value="VDA_002345"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0524">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1030724at2"/>
    <dbReference type="UniPathway" id="UPA00916">
        <property type="reaction ID" value="UER00889"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004747">
        <property type="term" value="F:ribokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019303">
        <property type="term" value="P:D-ribose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01174">
        <property type="entry name" value="ribokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01987">
        <property type="entry name" value="Ribokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011877">
        <property type="entry name" value="D_ribokin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001034">
        <property type="entry name" value="DeoR_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002139">
        <property type="entry name" value="Ribo/fructo_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08220">
        <property type="entry name" value="HTH_DeoR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00990">
        <property type="entry name" value="RIBOKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00420">
        <property type="entry name" value="HTH_DEOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51000">
        <property type="entry name" value="HTH_DEOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 8" id="KW-0630">Potassium</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HTH deoR-type" evidence="9">
        <location>
            <begin position="3"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="108"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="136"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="350"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="282"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="344"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="346"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="349"/>
            <end position="350"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="350"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="380"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="383"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="385"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ41313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="406" mass="45035" checksum="765EC64A2879B6FC" modified="2010-01-19" version="1">MKKLERQKFIKLKLAKDKKVYVSELARILQVTDRTIRSDLKYLSEKRVCVLFHGGAKLIDVQYDVEFKETSLHTMLKGLKNSYQPKEPSIKTEENNTETDVYVLGSFNIDIVTEVDNLPKIGQTQRATSTHFYPGGKGANQASAAATLCDKVHLTIKVGQDEFSEKAKSYLSSTNITSLTLLEDSQPHTGSAIVLVSSQTGNNMITIDLGANETIKTEEILQDIDLIREAKVFLTQLENNFDATRFAIEQAYSSQTLVILDPAPYREEVKQILPFIDIITPNEIEAEEISGIKITDISTAKDAAKAIYQQGVNHVIITMAEKGSILYNHLGFHYTPAYKSAVIDTSGAGDAFTGSLAAYLAKGVNLKQAINYATAFSSLKIEKKGASNMPDKGLITYRMNREYIIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYL0</accession>
    <name>D0YYL0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribonucleoside-diphosphate reductase</fullName>
            <ecNumber evidence="4">1.17.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_002373</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Genetic information processing; DNA replication.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ribonucleoside diphosphate reductase small chain family.</text>
    </comment>
    <dbReference type="EC" id="1.17.4.1" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299979.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002373"/>
    <dbReference type="EnsemblBacteria" id="EEZ41341">
        <property type="protein sequence ID" value="EEZ41341"/>
        <property type="gene ID" value="VDA_002373"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0208">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1384440at2"/>
    <dbReference type="UniPathway" id="UPA00326"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004748">
        <property type="term" value="F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009263">
        <property type="term" value="P:deoxyribonucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01049">
        <property type="entry name" value="RNRR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.620.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012348">
        <property type="entry name" value="RNR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033909">
        <property type="entry name" value="RNR_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030475">
        <property type="entry name" value="RNR_small_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000358">
        <property type="entry name" value="RNR_small_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23409">
        <property type="entry name" value="PTHR23409"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00268">
        <property type="entry name" value="Ribonuc_red_sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00368">
        <property type="entry name" value="RIBORED_SMALL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="377" mass="43387" checksum="208CC1519262C618" modified="2010-01-19" version="1">MAYSTFCQTHNDQLKEPMFFGQPVNVARYDQQKFEIFEKLIEKQLSFFWRPEEVDVSGDRIDYNNLPDHEKHIFISNLKYQTLLDSIQGRSPNVALLPIVSLPELETWIETWSFSETIHSRSYTHIIRNIVNDPAIVFDDIVSNEYIIKRAGDISRYYDELISATNDYHRLGEGTHTVDGKTITINLRDLKKKLYLCIMSVNALEAIRFYVSFACSFAFAERELMEGNAKIIKLIARDEALHLTGTQHILNLLRNGHDDPEMAEIAKESEAECFDIFKRAAEQEKEWAEYLFKDGSMIGLNKDILCQYVEYITNLRMNAVGLEHAYTGATQNPIPWINSWLSSDNVQVAPQEAEISSYLVGQIDNDVSVDDLGDFEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYN0</accession>
    <name>D0YYN0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Anthranilate synthase amidotransferase component</fullName>
            <ecNumber evidence="2">4.1.3.27</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002393</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="4.1.3.27" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300016.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002393"/>
    <dbReference type="EnsemblBacteria" id="EEZ41361">
        <property type="protein sequence ID" value="EEZ41361"/>
        <property type="gene ID" value="VDA_002393"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0512">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1561172at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004049">
        <property type="term" value="F:anthranilate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071704">
        <property type="term" value="P:organic substance metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd01743">
        <property type="entry name" value="GATase1_Anthranilate_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006221">
        <property type="entry name" value="TrpG/PapA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00566">
        <property type="entry name" value="trpG_papA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GATase" evidence="1">
        <location>
            <begin position="7"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="209" mass="22680" checksum="0C64D592A73C434A" modified="2010-01-19" version="1">MNNTHIVLLDNYDSFTYNLVDQFRSLGHSVTVFRNSADAYRLAQHIQAFPNAVLVLSPGPGAPNDAGCMPHLIELMKGKVPILGICLGHQAIVESYGGTVAGAGEIMHGKADMLEHNGHRIFGDLPSSFPIARYHSLVATQVVEPLHVIAKANQLIMAVVHEQDKVCGFQFHPESILTTQGAQLLAQTLDWISRPTTPLDLTTPAQNQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYP0</accession>
    <name>D0YYP0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Cardiolipin synthase A</fullName>
            <shortName evidence="7">CL synthase</shortName>
            <ecNumber evidence="7">2.7.8.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">clsA</name>
        <name evidence="9" type="ORF">VDA_002403</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>2 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) = a cardiolipin + glycerol</text>
            <dbReference type="Rhea" id="RHEA:31451"/>
            <dbReference type="ChEBI" id="CHEBI:17754"/>
            <dbReference type="ChEBI" id="CHEBI:62237"/>
            <dbReference type="ChEBI" id="CHEBI:64716"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsA sub-subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.-" evidence="7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300027.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002403"/>
    <dbReference type="EnsemblBacteria" id="EEZ41371">
        <property type="protein sequence ID" value="EEZ41371"/>
        <property type="gene ID" value="VDA_002403"/>
    </dbReference>
    <dbReference type="GeneID" id="57341393"/>
    <dbReference type="eggNOG" id="COG1502">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1881748at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008808">
        <property type="term" value="F:cardiolipin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032049">
        <property type="term" value="P:cardiolipin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00190">
        <property type="entry name" value="Cardiolipin_synth_ClsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022924">
        <property type="entry name" value="Cardiolipin_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030840">
        <property type="entry name" value="CL_synthase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025202">
        <property type="entry name" value="PLD-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13091">
        <property type="entry name" value="PLDc_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00155">
        <property type="entry name" value="PLDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04265">
        <property type="entry name" value="bac_cardiolipin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="7" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="36"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="8">
        <location>
            <begin position="219"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="8">
        <location>
            <begin position="400"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="224"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="226"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="231"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="405"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="407"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="487" mass="55469" checksum="6F593F46BF25A9E6" modified="2010-01-19" version="1">MEQFYQILAWLGVFLYWLIIAGVTVRVIFKRRAVGVALAWLMIIYIIPIGGVFAYILFGELNLGSKRAERAKEMLDPFAEWFQRLNDCPGHQPQNMSSNARPISDLCENRLGIPGLTENSLSLQNSPQTILRSIIDDINHAEHAIHMEFYIWNPGGMADEVAVAMVQAAKRGVKVKLLLDSAGSMRFFRSHWPKLMRNSGIDVVEALAVSPFRMFFRRLDLRLHRKIVVIDNLVAYTGSMNLVDPAFFKQDAGVGQWVDVMVRITGPTVPLLNCIQSWDWEVETGERHLPPLPVCAIPPQIPNHEVDTVQVIPSGPGMPDDIIHQVLLLSIYQAKESVVITTPYFVPSEHLLHALKGAAERGIAVHIVIPNKNDSTMVEWASRSFFNELLDSGVRIHRFHGGLLHTKSVVIDDTHCLIGTVNLDMRSLWLNFEVTMAVDNLEFTKQLSWLQQQYIADSEQIDRREWERRPMTHKLIEQFFYMFSPLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYP1</accession>
    <name>D0YYP1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hypothetical GGDEF family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002404</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002404"/>
    <dbReference type="EnsemblBacteria" id="EEZ41372">
        <property type="protein sequence ID" value="EEZ41372"/>
        <property type="gene ID" value="VDA_002404"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2199">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="2">
        <location>
            <begin position="228"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="374" mass="43408" checksum="46900341A2E34FC5" modified="2010-01-19" version="1">MGHFVINFKRLLYGIITVLVFAIFISANHFKLTSENISRQQNEAIWYILELNKEYGEIIYLLQKFELNQIESQQIALQYEVLWSRYSAILSNSKINYHNNLAALLHELEHHFSFLQSVDSRITPDHIDNPTQLTRALKNDYERLQKTFSQTLQLHEGTIDKQLDEINTLQNHFQVLLVVTFLLCLIVIVLLYYESLYHHQLAMQDALTEINNRLWLNKQLASMAQKKQPFRFYLIDLDGFKKINDSLGHQVGDIVLKTVAKRLQQLEGKSCFVARMGGDEFCLISTQSDNNKYLNQQIINCISKPVQYQHGFCHIAGSVGVSDYPQQSNTIYDLLQQADFAMYEAKQKGKNNIFFATEQSSQTKNTPSTHKMEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYQ3</accession>
    <name>D0YYQ3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Phage integrase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_002416</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300050.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002416"/>
    <dbReference type="EnsemblBacteria" id="EEZ41384">
        <property type="protein sequence ID" value="EEZ41384"/>
        <property type="gene ID" value="VDA_002416"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4974">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="745068at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044068">
        <property type="entry name" value="CB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004107">
        <property type="entry name" value="Integrase_SAM-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13495">
        <property type="entry name" value="Phage_int_SAM_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51900">
        <property type="entry name" value="CB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0229">DNA integration</keyword>
    <keyword evidence="3" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core-binding (CB)" evidence="6">
        <location>
            <begin position="2"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="Tyr recombinase" evidence="5">
        <location>
            <begin position="104"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="291" mass="33734" checksum="D218394E959DD522" modified="2010-01-19" version="1">MNKAQQHRSDYLYEQHLTHLTLQGKRPATIDAYSRALRRITHQLDKSPDTLTTDDLKRYFTQLIKTHSWSTVKIDRNGLQFFFKHVLQRDWEWLNIVKPPHVKTLPDILTPSEVSLLINATSQLRYQVFFLTLYSLGLRLGEGLNLTVGDIDSHRMLVHIRQGKGGKDRFIPLPRRTLYALRYYWQTHKNSRYLFPSQFNLNHTVMDRGGVQKAMKAVIKSCGITKSISPHNLRHSYATHLLERGLDLRSVQHLLGHNSLNATAKYTHLTDISRKNTTTTVNQLTNDLTLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ86</accession>
    <name>D0YZ86_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Flagellar motor switch protein FliG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002599</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002599"/>
    <dbReference type="EnsemblBacteria" id="EEZ41567">
        <property type="protein sequence ID" value="EEZ41567"/>
        <property type="gene ID" value="VDA_002599"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1536">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009288">
        <property type="term" value="C:bacterial-type flagellum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003774">
        <property type="term" value="F:cytoskeletal motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000090">
        <property type="entry name" value="Flg_Motor_Flig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023087">
        <property type="entry name" value="Flg_Motor_Flig_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011002">
        <property type="entry name" value="FliG_a-hlx"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30534">
        <property type="entry name" value="PTHR30534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01706">
        <property type="entry name" value="FliG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00954">
        <property type="entry name" value="FLGMOTORFLIG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48029">
        <property type="entry name" value="SSF48029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0966">Cell projection</keyword>
    <keyword evidence="3" id="KW-0969">Cilium</keyword>
    <keyword evidence="3" id="KW-0282">Flagellum</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FliG_C" evidence="2">
        <location>
            <begin position="60"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00025598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="175" mass="19495" checksum="60B4311018C5634C" modified="2010-01-19" version="1">MRIAHLEEVQPAALHELNDIMEKQFAGQSGAQAAKIGGLKAAAEIMNYLDNSMEGILMDQIREHDEDTAVQIQDLMFVFDNLIEMDDRSIQILLRDVPQEHLQCALKGADDPLRDKIFANMSKRAGEMLREDLEAMGPIRVSDVEASQKEILAIARRLADTGEIMLNGGGSEEYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ94</accession>
    <name>D0YZ94_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Flagellin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_002607</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Secreted</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Bacterial flagellum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the bacterial flagellin family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300469.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002607"/>
    <dbReference type="EnsemblBacteria" id="EEZ41575">
        <property type="protein sequence ID" value="EEZ41575"/>
        <property type="gene ID" value="VDA_002607"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1344">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="636786at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009288">
        <property type="term" value="C:bacterial-type flagellum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001492">
        <property type="entry name" value="Flagellin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046358">
        <property type="entry name" value="Flagellin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042187">
        <property type="entry name" value="Flagellin_C_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001029">
        <property type="entry name" value="Flagellin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42792">
        <property type="entry name" value="PTHR42792"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00700">
        <property type="entry name" value="Flagellin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00669">
        <property type="entry name" value="Flagellin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00207">
        <property type="entry name" value="FLAGELLIN"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="6" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6" id="KW-0969">Cilium</keyword>
    <keyword evidence="6" id="KW-0282">Flagellum</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Flagellin_N" evidence="4">
        <location>
            <begin position="5"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="Flagellin_C" evidence="5">
        <location>
            <begin position="382"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="468" mass="48375" checksum="CFDB60F033E40ECD" modified="2010-01-19" version="1">MAVTVNTNVSAMTAQRYLNSASNGVANSMEKLSSGLRINSAKDDAAGLQISNRLTSQTNGLNVAMRNANDGISMAQTAEGAMQESTNMLHRMRDLALQSANGSNSDDDRAAIQKEVTALQTEMTRIADTTTFGGQNLLDGSFGTKEFQIGANANETIGVSLSDISSDAIGNFAAGGSAGKIFGKGVQKSGAALDFAKVGATNKELKLDGPNGKETLTFAGNEKLTEVVSEINKANTGIKASTSVTTTIGNLASTETGKLVIGKDEFDLSKYKGDSKKLAEDLGKSGYSAEVADDGSTINLTAKDVDGIKVTGAAKDGVELGGQKAGAANDNIVADAQIKLSSSSNFKVGGALADDLTDSATGSLNSVKDIDLTTVDGSQNALDVIDAAIAGIDSQRADLGAVQNRFNHTLNNLSNINENVNASNSRIKDVDFAKETTNMTKNQILQQASTSILAQAKQIPQSALSLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZA6</accession>
    <name>D0YZA6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Chemotaxis protein CheV</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_002619</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300509.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002619"/>
    <dbReference type="EnsemblBacteria" id="EEZ41587">
        <property type="protein sequence ID" value="EEZ41587"/>
        <property type="gene ID" value="VDA_002619"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0784">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0835">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024181">
        <property type="entry name" value="Chemotax_regulator_CheV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036061">
        <property type="entry name" value="CheW-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002545">
        <property type="entry name" value="CheW-lke_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01584">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002867">
        <property type="entry name" value="CheV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00260">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50341">
        <property type="entry name" value="SSF50341"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50851">
        <property type="entry name" value="CHEW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CheW-like" evidence="3">
        <location>
            <begin position="19"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="180"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="307" mass="34080" checksum="A7C4B4D2FF8536DC" modified="2010-01-19" version="1">MTGILDSVNQRTQLVGQNRLELLTFRLMRRQRYGINVFKVKEVLQCPKLTTMPNLHPLVKGIAHIRGQTISVIDMSLATGGRPIEDLSNCFVIISEFNRSVQGFLVTSVERIINMNWESILPPPKGAGRSNYLTAVTEIDNELVEILDVEKILDEISPADTDITGTVFEELATQLPEVNRILVADDSAVARKQVQRAIEAIGYECVLVKDGREALNTLKEMAKEGSIYDQLALVISDIEMPEMDGYTLTAEIRNNPQLKNLHVILHTSLSGVFNQAMVERVGANAFIPKFNPDELGSAVLQAIPQTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZA8</accession>
    <name>D0YZA8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Negative regulator of flagellin synthesis</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Anti-sigma-28 factor</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">VDA_002621</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the FlgM family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300515.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002621"/>
    <dbReference type="EnsemblBacteria" id="EEZ41589">
        <property type="protein sequence ID" value="EEZ41589"/>
        <property type="gene ID" value="VDA_002621"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2747">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1833882at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044781">
        <property type="term" value="P:bacterial-type flagellum organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035890">
        <property type="entry name" value="Anti-sigma-28_factor_FlgM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007412">
        <property type="entry name" value="FlgM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031316">
        <property type="entry name" value="FlgM_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04316">
        <property type="entry name" value="FlgM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101498">
        <property type="entry name" value="SSF101498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03824">
        <property type="entry name" value="FlgM_jcvi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1005">Bacterial flagellum biogenesis</keyword>
    <keyword evidence="11" id="KW-0966">Cell projection</keyword>
    <keyword evidence="11" id="KW-0969">Cilium</keyword>
    <keyword evidence="11" id="KW-0282">Flagellum</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0678">Repressor</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="FlgM" evidence="10">
        <location>
            <begin position="44"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ41589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="106" mass="11526" checksum="013A53F06B413506" modified="2010-01-19" version="1">MAGIDQLRQNSQAMTTMRSQQQKVNDNASSTSNTTASTTPTQHDEISLSAQGKAVGQIHQQLATEPSFDADKVAKIKEAISNGSYKVDPDKLASNIMKFENELKDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZE2</accession>
    <name>D0YZE2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9 11">FAD:protein FMN transferase</fullName>
            <ecNumber evidence="3 9 11">2.7.1.180</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Flavin transferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">VDA_002655</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9 11">
            <text>FAD + L-threonyl-[protein] = AMP + FMN-L-threonyl-[protein] + H(+)</text>
            <dbReference type="Rhea" id="RHEA:36847"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11061"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:74257"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.1.180"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="10">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="10">Magnesium. Can also use manganese.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cell inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 11">Belongs to the ApbE family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.180" evidence="3 9 11"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300617.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002655"/>
    <dbReference type="EnsemblBacteria" id="EEZ41623">
        <property type="protein sequence ID" value="EEZ41623"/>
        <property type="gene ID" value="VDA_002655"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2021063at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017013">
        <property type="term" value="P:protein flavinylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024932">
        <property type="entry name" value="ApbE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003374">
        <property type="entry name" value="ApbE-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30040">
        <property type="entry name" value="PTHR30040"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02424">
        <property type="entry name" value="ApbE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006268">
        <property type="entry name" value="ApbE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143631">
        <property type="entry name" value="SSF143631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 11" id="KW-0274">FAD</keyword>
    <keyword evidence="5 9 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="11 12" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="8 9 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <keyword evidence="6 9 11" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005968283" description="FAD:protein FMN transferase" evidence="11">
        <location>
            <begin position="21"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="290"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="294"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR006268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR006268-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ41623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="341" mass="37775" checksum="B606913FE1D5451B" modified="2010-01-19" version="1">MKQLWVRLTAILAVSLFLTACGDQREQVHLDGTTMGTYYSIKYISQPDLPTPATIKAEIDRKLELVNDQMSTYRPSSELSRFNQHQSSEPFPVSAATAKVIREALRISQLSNGAYDVTVGPLVNLWSFGPEARPEKMPTEQELASRQAEVGYHHLSVTDDNKLIKDIPGLYVDLSSIAKGYGVDVIAEYLASLNIKDYMVDVGGEIRVKGANVNNVPWRIAIEKPISNERAVQDIIQVGDNGIATSGDYRNYFEQDGVRYSHLINPRTGKPIANHVVSVTVISPNSMTADAYATTFSVMGEHESIALANKEQLPVMLIVKTKDGFKEYASDTFAQYVVKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZL1</accession>
    <name>D0YZL1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">Malate synthase</fullName>
            <ecNumber evidence="2 7">2.3.3.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_002724</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>acetyl-CoA + glyoxylate + H2O = (S)-malate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18181"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.3.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Carbohydrate metabolism; glyoxylate cycle; (S)-malate from isocitrate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the malate synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.3.9" evidence="2 7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002724"/>
    <dbReference type="EnsemblBacteria" id="EEZ41692">
        <property type="protein sequence ID" value="EEZ41692"/>
        <property type="gene ID" value="VDA_002724"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2225">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00703">
        <property type="reaction ID" value="UER00720"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004474">
        <property type="term" value="F:malate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006097">
        <property type="term" value="P:glyoxylate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00727">
        <property type="entry name" value="malate_synt_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1220.12">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044856">
        <property type="entry name" value="Malate_synth_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011076">
        <property type="entry name" value="Malate_synth_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006252">
        <property type="entry name" value="Malate_synthA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001465">
        <property type="entry name" value="Malate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019830">
        <property type="entry name" value="Malate_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046363">
        <property type="entry name" value="MS_N_TIM-barrel_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42902">
        <property type="entry name" value="PTHR42902"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01274">
        <property type="entry name" value="Malate_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001363">
        <property type="entry name" value="Malate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51645">
        <property type="entry name" value="SSF51645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01344">
        <property type="entry name" value="malate_syn_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00510">
        <property type="entry name" value="MALATE_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3 7" id="KW-0329">Glyoxylate bypass</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="167"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001363-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ41692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="534" mass="60621" checksum="D3A4EFB1D58BF943" modified="2010-01-19" version="1">MTMPMNHQMKLSLQVAITDAQQEILTTEALSFLEQLTDRFAAQVSDLLQAREQRQALIDNGQLPDFLPETQSIRDSEWQIQSIPKDLQDRRVEITGPVERKMVINALNANVKVFMADFEDSFSPVWDEVIQGQRNLRDAILGSISYTNPTTGKHYQLKDDPAVLICRVRGLHLPEKHIYFNGMPIPGALLDFALYFYHNHRALLEKGSGPYFYLPKLQSHQEAAWWSQIFSFTEDLFELPRGTIKATVLIETLPAVFEMDEILYALKEHIVGLNCGRWDYIFSYIKTLKNYPDRVLPDRQVVTMEKPFLNAYSRLLVKTCHRRGAFAMGGMAAFIPDKDPERNAWVLNKIQTDKSLEAHNGHDGTWVAHPGLADTARAVFDQVLGSRSNQLDVTRSDDAPITASELLAPCEGDRTEEGMRHNIRVAVQYIEAWISGNGCVPIYGLMEDAATAEISRASIWQWIKHGKALSNGKVVTKALFEQMLAEEMAVLEQELGSRIFEQGNYQQAAKFMNEITTSDELETFLTLPGYQYLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZQ1</accession>
    <name>D0YZQ1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002764</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300941.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002764"/>
    <dbReference type="EnsemblBacteria" id="EEZ41732">
        <property type="protein sequence ID" value="EEZ41732"/>
        <property type="gene ID" value="VDA_002764"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1591999at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="27"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="407" mass="46227" checksum="F81DC694B250BA84" modified="2010-01-19" version="1">MDNKVNVINFVPEELPSYRPDVDVLYSKELPKEGVRTTIIGMPKDETIKIESNDSTLVTSKKTTNRHLDSLVYFFTAAKMSFKAKKNGFQLIQVRDMVWVGLICLLIAKMIKLPYTYWVSFLYAESRSMRARDKSENIPSWKRPIILARGLLEEFILYHIILPHSDRVYAQSDFMLNYMKNKGIDENSMMVVPMGVDFEKIDAFSETEAKKIESWGDAPVIGYLGSLDRLRKLEVIIEAFQEAKKTVPELKLLFVGDSEVAKDRDFLQQTADDMGLTEDFCITGWVQTHEAWAYLKGVDMVIGFMNRGLLLDVSTPTKAMEYMALKKPMICNDSPDQQFVIQESGCGRVTDGSVKSYAQSMIELALQPMTQSELDAGFNYIKNNRSYASIGQQVAADIKNVVNQNNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZQ4</accession>
    <name>D0YZQ4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Capsular polysaccharide synthesis enzyme CpsD exopolysaccharide synthesis</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_002767</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300949.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002767"/>
    <dbReference type="EnsemblBacteria" id="EEZ41735">
        <property type="protein sequence ID" value="EEZ41735"/>
        <property type="gene ID" value="VDA_002767"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0489">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3206">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1184929at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009103">
        <property type="term" value="P:lipopolysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032807">
        <property type="entry name" value="GNVR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003856">
        <property type="entry name" value="LPS_length_determ_N_term"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033756">
        <property type="entry name" value="YlxH/NBP35"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13807">
        <property type="entry name" value="GNVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10609">
        <property type="entry name" value="ParA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02706">
        <property type="entry name" value="Wzz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="423"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="domain" description="Wzz" evidence="8">
        <location>
            <begin position="15"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="GNVR" evidence="9">
        <location>
            <begin position="372"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="281"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ41735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="699" mass="77914" checksum="F70A04A9211AF761" modified="2010-01-19" version="1">MASLFVEDGSKLESTIDFSRFLKAAKKNWWKIIAFSVLTTGASIPLIQKLTPKYEAYATVLLKAELTNPTTFAKVVDFDSTRKEYYETQYQLLKSRRVMSQVVDDLKLYELPEFIGKKEVKDDSLARQKERSIKYLTKHLSISPVRKTQMVEVGFESTDPKIAASVANEIVDVFSHFSINDNHEASLNVSNLLAKQVTDLDTQLKQKEAKLNDFLKKEGLITFRGVDGFQTEQLSLLTDSLATATAQRANLEAIYKTTRDAKKLGINGLVGIPDVSRHPQMENLRQMIIEQRTELSNLEDRYGPKYEKVIQARSQLNILQAQASRLVNEITSGIKEQYQAAVLKENQLQAEVNKQANAFQLLGDKKTRYDNMMDDISQTRELYNELLKRQNQTQVSSQFSESSAKIIDQAIIPLKPTKPNKTLLIAVIAIMSLLTSTLFVIVMAAINNKVMSIAEVKRRLGLPVLGEVRAYSQQVTPKNIINNSSDLNTLDEASFGIRSQLLLQEDVAQVYVVTSATAQEGKSSIATLVAKALAVDSKVLLIDMDLRSSQLTQSLGCTEILGLTDLLSQQLSVKDAITHTQSIDFLSVGQEANQSPLITLTNKNLEKVFTELRQLYDFIIIDTPAVLDSKDAILTSKHADKVLFVTASNYNSSNICVSAIDLLKQYGSQVVGCVLNKVDTNLLESNENLQIAPSKDVLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZV0</accession>
    <name>D0YZV0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Nucleoside permease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_002813</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002813"/>
    <dbReference type="EnsemblBacteria" id="EEZ41781">
        <property type="protein sequence ID" value="EEZ41781"/>
        <property type="gene ID" value="VDA_002813"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1972">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005337">
        <property type="term" value="F:nucleoside transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008276">
        <property type="entry name" value="C_nuclsd_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018270">
        <property type="entry name" value="C_nuclsd_transpt_met_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011657">
        <property type="entry name" value="CNT_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002668">
        <property type="entry name" value="CNT_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011642">
        <property type="entry name" value="Gate_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10590">
        <property type="entry name" value="PTHR10590"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07670">
        <property type="entry name" value="Gate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07662">
        <property type="entry name" value="Nucleos_tra2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01773">
        <property type="entry name" value="Nucleos_tra2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00804">
        <property type="entry name" value="nupC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="24"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="86"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="164"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="192"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="250"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="284"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="371"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="410"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleos_tra2_N" evidence="7">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="Gate" evidence="9">
        <location>
            <begin position="90"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleos_tra2_C" evidence="8">
        <location>
            <begin position="192"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ41781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="433" mass="44919" checksum="32BE1ED122EF9D6B" modified="2010-01-19" version="1">MVVLLAIAVLLSDNRKAINLRTVGGAFAIQFLLGAFVLYVPVGRDVLYGMSQGVANVIAYGNDGINFLFGGLTSDKMFEVFGGGGFVFALRVLPVIVFFSALISVLYYLGVMQIVINVLGGGLRKVLGTSHAESMSATANIFVGQTEAPLVVRPFVPKMTQSELFAVMCGGLASVAGGVLAGYASMGVPLEYLIAASFMAAPGGLLFAKIIKPETEQPVEQLADDDDNADEKPANVIDAAAAGASSGMQLALNVGAMLLAFIGLIALINGLLGGVGGWFGMPHLTLELILGYVFSPLAFLIGVPWNESLVAGSFIGQKVVVNEFVAYLNFAPYISTTAQQCTMVAADVVKETLPLCVETTKAVMSTKTQAIVSFALCGFANLSSVAILLGGLGGLAPTRRAEIARFGMKAVAAGTLSNLMSATIAGLFVSLSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z010</accession>
    <name>D0Z010_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0246 protein VDA_002873</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002873</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0246 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301254.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002873"/>
    <dbReference type="EnsemblBacteria" id="EEZ41841">
        <property type="protein sequence ID" value="EEZ41841"/>
        <property type="gene ID" value="VDA_002873"/>
    </dbReference>
    <dbReference type="GeneID" id="57340837"/>
    <dbReference type="eggNOG" id="COG3022">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1361974at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00652">
        <property type="entry name" value="UPF0246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005583">
        <property type="entry name" value="YaaA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30283">
        <property type="entry name" value="PTHR30283"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03883">
        <property type="entry name" value="H2O2_YaaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="257" mass="29131" checksum="1A85DEE58CBC6568" modified="2010-01-19" version="1">MLIVVSPAKTLDYESPLVTEQYTLPELTEHSQQLIEVCRELTPMDIARLMKVSDKIAGLNAARFAEWVPTFTPENARPAMFAFKGDVYTGLAAETMTDEQIAYAQQHFRMLSGLYGLLRPLDLMQPYRLEMGTKLENPRGANLYQFWGNIITDKVNLALAEQGDDILVNLASNEYFKSVKPKQVKGTIITPVFKDAKKGQYKVISFYAKKARGLMARYIIDNQIDSIEKLKEFDAAGYYFVAAESTATELVFKREEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z013</accession>
    <name>D0Z013_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Hemerythrin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002876</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301261.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002876"/>
    <dbReference type="EnsemblBacteria" id="EEZ41844">
        <property type="protein sequence ID" value="EEZ41844"/>
        <property type="gene ID" value="VDA_002876"/>
    </dbReference>
    <dbReference type="GeneID" id="57340834"/>
    <dbReference type="eggNOG" id="COG3945">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1701106at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012312">
        <property type="entry name" value="Hemerythrin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01814">
        <property type="entry name" value="Hemerythrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hemerythrin" evidence="1">
        <location>
            <begin position="2"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="176" mass="21283" checksum="AE0BB5041EA0F7E4" modified="2010-01-19" version="1">MLDRIHIEHGNINLLLEILLQKARLVEDGGKIDYHLIQDIIHYLQYQADRYHHPKEDILYHYYLAHYGENQSIKNLEQEHIELTQLTAEFADIVDMILLDSVIPQEIFLQKLHNFAMRQKAHLQLEEREIFPLLRRDFSPYDWRCVSEQYQDDIDDPLFGRKVADRYRNLHNYIDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z047</accession>
    <name>D0Z047_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glucosamine-link cellobiase</fullName>
            <ecNumber evidence="5">3.2.1.21</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_002910</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.2.1.21" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301323.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002910"/>
    <dbReference type="EnsemblBacteria" id="EEZ41878">
        <property type="protein sequence ID" value="EEZ41878"/>
        <property type="gene ID" value="VDA_002910"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502Z8YH">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1226595at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008810">
        <property type="term" value="F:cellulase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102483">
        <property type="term" value="F:scopolin beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02850">
        <property type="entry name" value="E_set_Cellulase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004197">
        <property type="entry name" value="Cellulase_Ig-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001701">
        <property type="entry name" value="Glyco_hydro_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00759">
        <property type="entry name" value="Glyco_hydro_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3 5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="579" mass="65744" checksum="F31318BEDE29DF30" modified="2010-01-19" version="1">MQLLTNHLGYERLGSKQAIILTPEPLVTPGSAELVSYPSGQTVMTLPIKANTPIAQWHIGLTYQVDFSACQQVGQYAIRYQGVLSSCFTIAEGLLFEQTFSDVIHYFKSQRCTGIYQQADKSIPLLGTDERVDVHGGWYDASGDISKYLSHLSYGNYLNPQQTPMVVWNMLKAYQLLEDEADVAKFTRVRLLEEALYGADFLVRMQHPDGYFYMTVFDQWSKDPARRDICAFATQQGDKSADFQAAFRQGGGIAIAALASAARIHQLASVQESPYLGQTNHQEYLACAERGYWHLKEYNLNYLNDGHENLIDEYCALMAAVELYKTTQNVRYIQEARTWALRVMSRQCSDEQQQYFWAANSDGSRPYYHAAEAGLPAIALLQYVAIEPQDQERLAAEQVIKQALQFELTISQEESNPFGYPRQYIKAIDGQKQSAFFMPHNNETGYWWQGENARLGSLATLAYFATAHLPNDTLTQPLKRYAHQLLDWIIGLNPYDMCMLDGHGRNNPDYLPELGFANAPGGVCNGITSGFDNEQDIAFKPAKQKDDMLQNWRWGEQWIPHGAWYLLAITAQYKERHHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z075</accession>
    <name>D0Z075_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Type I secretion TolC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_002938</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301388.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002938"/>
    <dbReference type="EnsemblBacteria" id="EEZ41906">
        <property type="protein sequence ID" value="EEZ41906"/>
        <property type="gene ID" value="VDA_002938"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1538">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1099555at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019867">
        <property type="term" value="C:outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010130">
        <property type="entry name" value="T1SS_OMP_TolC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01844">
        <property type="entry name" value="type_I_sec_TolC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018722" evidence="3">
        <location>
            <begin position="23"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="434" mass="47390" checksum="CD840C41DA22EC58" modified="2010-01-19" version="1">MKKLLPLFISVAFGGLSQSALADNLAEIYQQAKQNDPQLLKAAADKDAAFEAINSARSSLLPQINLSAGYKGNFMDADTPAVDNHGFNTGLQLSQSIYNRSSWVNLDISEQQARQSDAAYAAAQQALIMRVSKAYFDVLKAQDDLTFVRAEKAAVGRQLEQMKQRFDVGLSAITDVYDAQAQYDSVLASEILKENALTNSYEELREITGQAHKNLDILDTKSFSASNPGKPVNDLVKGAETENLTLLTYRIAQDVARNKISLAESGHLPTLSFDTGYSYDQTRMGNDDGSLTAGVTMNLPVYTGGRTTSEVKQAQFAYVSASEQLEQQYRSVVKDVRAYYNNINSSIASLRAYQQSVVSAKSALEATEAGFDVGTRTIVDVLNSTQSLYNANSQLADARYNYILSQLQLKQAVGTLSEQDILDINQGLKAVAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0A8</accession>
    <name>D0Z0A8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RNA polymerase-associated protein RapA</fullName>
            <ecNumber evidence="8">3.6.4.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">ATP-dependent helicase HepA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rapA</name>
        <name evidence="11" type="ORF">VDA_002971</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Interacts with the RNAP. Has a higher affinity for the core RNAP than for the holoenzyme. Its ATPase activity is stimulated by binding to RNAP.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the SNF2/RAD54 helicase family. RapA subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301439.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002971"/>
    <dbReference type="EnsemblBacteria" id="EEZ41939">
        <property type="protein sequence ID" value="EEZ41939"/>
        <property type="gene ID" value="VDA_002971"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0553">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="291634at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140658">
        <property type="term" value="F:ATP-dependent chromatin remodeler activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016817">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01821">
        <property type="entry name" value="Helicase_RapA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023949">
        <property type="entry name" value="Helicase_RapA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022737">
        <property type="entry name" value="RapA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040765">
        <property type="entry name" value="Tudor_1_RapA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040766">
        <property type="entry name" value="Tudor_2_RapA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12137">
        <property type="entry name" value="RapA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18339">
        <property type="entry name" value="Tudor_1_RapA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18337">
        <property type="entry name" value="Tudor_RapA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0010">Activator</keyword>
    <keyword evidence="3 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 8" id="KW-0347">Helicase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 8" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="164"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="493"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DEAH box" evidence="8">
        <location>
            <begin position="280"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="177"/>
            <end position="184"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ41939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="972" mass="110134" checksum="3C954CE56F652371" modified="2010-01-19" version="1">MPFALGQRWISDTESDLGLGTVVALDARTVTLMFSASEENRLYARNDAPVTRVMFNVGDVVESHEGWTLKVENIVEEKGVLTYVGTRTDTQEEDVALRELFLNHQIRFNKPQDKLFAGQIDRMDRFALRYRALKNQYEQHKSPLRGLCGMRAGLIPHQLYIAHEVGRRYAPRVLLADEVGLGKTIEAGMIIHQQVLSGRAERILILVPETLQHQWLVEMMRRFNLHFSIFDEERCVEAYADAANPFDTAQYVLCSLDFLRKSRRRFEQALEADWDLLVVDEAHHLEWSEDKPSRQYQVVEEIAEKTPSVLLLTATPEQLGRESHFARLRLLDPDRFYDYQEFVEEERKYEPVADAVSRLLSGETLTEQEKETLAQLLPEQDIAPTLAFIESSSLDNGEAIAARNELIANLMDRHGTGRVLFRNTRAAIKGFPQRHLNMYPLAMPTQYQTAMRVASMMGGRMSPEQKVMKLLYPEDIYQEFEGDTATWWNFDPRVTWLIEHLKANRGEKVLVICSRAQTALTLEQALREREGIRASVFHEGMSIIERDKAAAYFAQDEEGAQVLLCSEIGSEGRNFQFSNQLVMFDLPNNPDLLEQRIGRLDRIGQKRDIEIHVPHLEGTSQALLARWYNEGLNAFEETCPTGRAVYDAHQDALLALLASEKHDEAELENLITSSAAMHNELKAKLEQGRDRLLEMHSNGGEAAHALVDEISAKDGDTNLVTFALGLFDTIGLNQDDRGENAIVVTPSEHMMVSSYPGLPYDGCTITFDRDTALSREDMHFISWEHPMIQGGIDLLLTEGVGTTAVSLLKNKALPVGTLLLELVYVVDAQAPKQSGIGRFLPKTPIRILLDSKGNNLAANVEFESFNRQLSPVNRHLGSKLVNSVQKDIHVLIEHAERAIETELDQVRQQAQAEMEATLQAEFNRLQVLKAVNPNIRDDELELLQTQIQELTNYIGKAQIQLDSLRLIVVSHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0H1</accession>
    <name>D0Z0H1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">tRNA dimethylallyltransferase</fullName>
            <ecNumber evidence="5">2.5.1.75</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Dimethylallyl diphosphate:tRNA dimethylallyltransferase</fullName>
            <shortName evidence="5">DMAPP:tRNA dimethylallyltransferase</shortName>
            <shortName evidence="5">DMATase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Isopentenyl-diphosphate:tRNA isopentenyltransferase</fullName>
            <shortName evidence="5">IPP transferase</shortName>
            <shortName evidence="5">IPPT</shortName>
            <shortName evidence="5">IPTase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">miaA</name>
        <name evidence="9" type="ORF">VDA_003035</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 5 7">Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5 6">
            <text>adenosine(37) in tRNA + dimethylallyl diphosphate = diphosphate + N(6)-dimethylallyladenosine(37) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:26482"/>
            <dbReference type="Rhea" id="RHEA-COMP:10162"/>
            <dbReference type="Rhea" id="RHEA-COMP:10375"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57623"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74415"/>
            <dbReference type="EC" id="2.5.1.75"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 5 8">Belongs to the IPP transferase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.75" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301655.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003035"/>
    <dbReference type="EnsemblBacteria" id="EEZ42002">
        <property type="protein sequence ID" value="EEZ42002"/>
        <property type="gene ID" value="VDA_003035"/>
    </dbReference>
    <dbReference type="GeneID" id="57340509"/>
    <dbReference type="eggNOG" id="COG0324">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1069591at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052381">
        <property type="term" value="F:tRNA dimethylallyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00185">
        <property type="entry name" value="IPP_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039657">
        <property type="entry name" value="Dimethylallyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018022">
        <property type="entry name" value="IPT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11088">
        <property type="entry name" value="PTHR11088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00174">
        <property type="entry name" value="miaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 6" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="15"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with substrate tRNA" evidence="5">
        <location>
            <begin position="38"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with substrate tRNA" evidence="5">
        <location>
            <begin position="162"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with substrate tRNA" evidence="5">
        <location>
            <begin position="243"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with substrate tRNA" evidence="5">
        <location>
            <begin position="276"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="13"/>
            <end position="20"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Interaction with substrate tRNA" evidence="5">
        <location>
            <position position="104"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with substrate tRNA" evidence="5">
        <location>
            <position position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ42002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="311" mass="34796" checksum="75FD9A365DB3A950" modified="2010-01-19" version="1">MSKPLPQAIFLMGPTASGKTDLAIRLRQELPVELISVDSALIYKGMDIGTAKPDAHELALAPHRLIDIRDPAQSYSAADFRADALKEMADIVAAGRIPLLVGGTMLYYKALLEGLSPLPAADPEIRAGIEQEAKEKGWQALHEELVRIDPVSGARIHPNDPQRLSRALEVFRISGKTLTELTKTQGDALPYKVHQFAIAPKDRTVLHQRIELRFEKMMAAGFEQEVKALYERGDLHPDLPSIRCVGYRQMWDYLDGHCDQDEAVFRGICATRQLAKRQITWLRSWKDLTWLDSGDVDTSLQTVTNSVRYDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z164</accession>
    <name>D0Z164_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_003278</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302367.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ42245">
        <property type="protein sequence ID" value="EEZ42245"/>
        <property type="gene ID" value="VDA_003278"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0697">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1515911at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="156"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="182"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="214"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="245"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="268"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="6"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="155"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ42245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="299" mass="32811" checksum="8CCF16E65D04C64D" modified="2010-01-19" version="1">MNERKALLYGLSAVLLWSTVATAFKITLNYFSPVQMLVVASAVSAIALTGISFYQGTLSQLKRTLLLRPWYYLALGLINPLAYYLVLFKAYELLPASQAQPLNYSWAITLTLMAALFLGQKIRRQDWIACLFGYLGVIVIATKGDITALQFDSPTGVALALLSTLLWALYWIINTKNSADPVLGVLLGFLLSLPFSLGLSFAIDTWHAVPWQGWLAVSYVGLFEMGITFVLWLSALKLTTNTAKISNLIFISPFISLLLLATIIGETIAPSTIIGLGLIIVGLMIQQLKSSKQKKACHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z177</accession>
    <name>D0Z177_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA-uridine aminocarboxypropyltransferase</fullName>
            <ecNumber evidence="1">2.5.1.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_003291</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.5.1.25" evidence="1"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302409.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003291"/>
    <dbReference type="EnsemblBacteria" id="EEZ42258">
        <property type="protein sequence ID" value="EEZ42258"/>
        <property type="gene ID" value="VDA_003291"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3148">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1600710at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016432">
        <property type="term" value="F:tRNA-uridine aminocarboxypropyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005636">
        <property type="entry name" value="DTW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039262">
        <property type="entry name" value="DTWD2/YfiP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21392">
        <property type="entry name" value="PTHR21392"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03942">
        <property type="entry name" value="DTW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01144">
        <property type="entry name" value="DTW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="DTW" evidence="5">
        <location>
            <begin position="1"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ42258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="193" mass="22272" checksum="832764E779DFD933" modified="2010-01-19" version="1">MACPRCGFVHNCICHLEPTLSCSAHFVLLTHPKELNKETNTGVLMTRTLPHCQLIAWHRTEPDTTLIAQLNSDQYQPWLLFPADEQTPATHWQPDMSKTPLFIILDATWQEARKMVRKSPYLQSLPRLQLNTEHPSHYQLRRNQQPGNLCTCEAGIELLKLLQNPEQAQQLQQYFTGFIDVFHADRSGHHISQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z187</accession>
    <name>D0Z187_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003301</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003301"/>
    <dbReference type="EnsemblBacteria" id="EEZ42268">
        <property type="protein sequence ID" value="EEZ42268"/>
        <property type="gene ID" value="VDA_003301"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3776">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009525">
        <property type="entry name" value="DUF1145"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38775">
        <property type="entry name" value="PTHR38775"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06611">
        <property type="entry name" value="DUF1145"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="56" mass="6588" checksum="7B310C239C3C6970" modified="2010-01-19" version="1">MALYIMTAFLFMMHGLQMLIFIGAFGDKITMSGWEKWSILIFGIFALLDIRRKHMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z189</accession>
    <name>D0Z189_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Signal recognition particle receptor FtsY</fullName>
            <shortName evidence="5">SRP receptor</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ftsY</name>
        <name evidence="8" type="ORF">VDA_003303</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
            <orientation evidence="5">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the GTP-binding SRP family. FtsY subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302443.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003303"/>
    <dbReference type="EnsemblBacteria" id="EEZ42270">
        <property type="protein sequence ID" value="EEZ42270"/>
        <property type="gene ID" value="VDA_003303"/>
    </dbReference>
    <dbReference type="GeneID" id="57340257"/>
    <dbReference type="eggNOG" id="COG0552">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="656414at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031226">
        <property type="term" value="C:intrinsic component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00920">
        <property type="entry name" value="FtsY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013822">
        <property type="entry name" value="Signal_recog_particl_SRP54_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004390">
        <property type="entry name" value="SR_rcpt_FtsY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036225">
        <property type="entry name" value="SRP/SRP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000897">
        <property type="entry name" value="SRP54_GTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042101">
        <property type="entry name" value="SRP54_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43134:SF7">
        <property type="entry name" value="PTHR43134:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00448">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02881">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00962">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00963">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47364">
        <property type="entry name" value="SSF47364"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00064">
        <property type="entry name" value="ftsY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00300">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 5 8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SRP54" evidence="7">
        <location>
            <begin position="432"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="27"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="42"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="265"/>
            <end position="272"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="347"/>
            <end position="351"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="411"/>
            <end position="414"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ42270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="462" mass="50360" checksum="DA1D1CE6F82FC153" modified="2010-01-19" version="1">MAEKKKRGLFSWLGFGSEEKSEHSEQTTEINSVIEGQDESPKSQTSDAKDAEIAHNDDAKNDAADSAKDTVTEPVAKAEPEAEASISQLEAVEEQVELASINADAASDDAQIEAEIVSEQLQAKESAEHLRNEETENNAELESPVIAIAEQEKPKSEGFFARLMRGLRKTKENFGSSFFSLFKGKKIDDELFEELEEQLLIADVGMDTTVKIIENLTEKASRKELKDGEALYGLLKDELAEMLAKVEQPFEIDTSKKPYVILMVGVNGVGKTTTIGKLAKKFQSEGKSVMLAAGDTFRAAAVEQLQVWGERNQVPVIAQHTGADSASVIFDAIESAKAKNIDVIIADTAGRLQNKANLMEELRKIVRVMKKIDPDAPHEIMLTLDAGTGQNAISQAKLFSEVAPVSGITLTKLDGTAKGGVIFAIADQFHIPIRYIGIGEGIDDLRPFAADEFIEALFTDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z197</accession>
    <name>D0Z197_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Glycerol-3-phosphate dehydrogenase</fullName>
            <ecNumber evidence="6">1.1.5.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_003311</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:18977"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.1.5.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.5.3" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003311"/>
    <dbReference type="EnsemblBacteria" id="EEZ42278">
        <property type="protein sequence ID" value="EEZ42278"/>
        <property type="gene ID" value="VDA_003311"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0578">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009331">
        <property type="term" value="C:glycerol-3-phosphate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052591">
        <property type="term" value="F:sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006072">
        <property type="term" value="P:glycerol-3-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.870">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031656">
        <property type="entry name" value="DAO_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038299">
        <property type="entry name" value="DAO_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000447">
        <property type="entry name" value="G3P_DH_FAD-dep"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11985">
        <property type="entry name" value="PTHR11985"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16901">
        <property type="entry name" value="DAO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01001">
        <property type="entry name" value="FADG3PDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00977">
        <property type="entry name" value="FAD_G3PDH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3 6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5 6 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAO" evidence="7">
        <location>
            <begin position="28"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="domain" description="DAO_C" evidence="8">
        <location>
            <begin position="404"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF16901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ42278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="524" mass="59048" checksum="2D25E881CE5F4292" modified="2010-01-19" version="1">MFERSFLCSFYNNGETGDDMAQDNSILDIIVVGGGINGAGIATDAAGRGLRVGLYEASDFASATSSASSKLIHGGLRYLEHYEFRLVGEALAEREVLLKKLPHIAHPMRFRLPHQPHLRPAWMIRAGLFLYDHLGKRTTLPASCGLRFGADSVLVPEITKGFEYSDCWVDDARLVILNAMSVAQAGGEVRNRCRVERAVRVGDIWQVTIRDLLTDHTFERQAHALVNAAGPWVKTFFDQSTDLTSPRNIRLIKGSHIVVPRVHEQTQAYILQNEDNRIVFVIPYLDRFSIIGTTDVEYQGNPRDVAIDEQEIGYLLDVYNRHFKKQLERQDVVWTYSGVRPLCDDESDSPQAITRDYTLELEQEGTQAPLLSIFGGKLTTYRKLAEAAMVKLAPFFPQMGPSWTADSYLPGGADGFTRETFARELKQRYPWLTEFTCLRLATNYGVCANTMLALVQCEADMGTDFGEQFYQVELEYLRQHEFVQTVEDALWRRSKMGLYLTKDQQQRVAEYLIAGQAAASESAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1B5</accession>
    <name>D0Z1B5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcription accessory protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_003329</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302502.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003329"/>
    <dbReference type="EnsemblBacteria" id="EEZ42296">
        <property type="protein sequence ID" value="EEZ42296"/>
        <property type="gene ID" value="VDA_003329"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2183">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="120764at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05685">
        <property type="entry name" value="S1_Tex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.650">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3500.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041692">
        <property type="entry name" value="HHH_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044146">
        <property type="entry name" value="S1_Tex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023323">
        <property type="entry name" value="Tex-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023319">
        <property type="entry name" value="Tex-like_HTH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018974">
        <property type="entry name" value="Tex-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032639">
        <property type="entry name" value="Tex_YqgF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006641">
        <property type="entry name" value="YqgF/RNaseH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037027">
        <property type="entry name" value="YqgF/RNaseH-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17674">
        <property type="entry name" value="HHH_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09371">
        <property type="entry name" value="Tex_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16921">
        <property type="entry name" value="Tex_YqgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00732">
        <property type="entry name" value="YqgFc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S1 motif" evidence="2">
        <location>
            <begin position="651"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="716"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="716"/>
            <end position="752"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ42296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="776" mass="85596" checksum="91B9F8E09BB920BC" modified="2010-01-19" version="1">MNNSINQLIASELNVRLEQINAAVSLLDDGNTVPFVARYRKEVTGGLDDTQLRNLESRLGYLRELDDRRKVILKSISEQNKLTPQLEAEINQADSKTRLEDLYLPYKPKRRTKGQIAIEAGIEPLADLLWQHPDTDPEIAAHNHIDADKGFADTKAVLDGARAILMERFAEDAALLEKIRRHLTEQAELTSRVVDGKEHEGAKFKDYFEYSEKVKQIPSHRALALFRGRNEGFLQLSLNADPNQDESVRGSYCEVIIADHYKVQLGTKPSDAWRKQVISWAWRIKILMHMETELMAALRERAEDGAMQVFADNLKDLLMAAPAGPRVTLAIDPGLRTGSKIAVVDETGKLLDTATIYPHAPHNKIAEAGKVVLAFIAKYQVNLIAIGNGTASRETDSFVAQLIKDNGLKVQSIMVSEAGASVYSASELAANEFPNLDVSIRGAVSIGRRLQDPLAELVKIDPKSIGVGQYQHDVSQSMLAKRLDAVVEDCVNAVGVDVNTASAPLLTRVAGLNATIAQNIVNYRDEKGRFEARTTLKKVARLGPKAFEQCAGFLRIMNGKNPLDGSAVHPESYEVVKRIASANDKSLDAIIGNSEFLRTLKAVDYTDQHFGLPTVTDIISELDKPGRDPRPEFKTATFAEGVNEVKDLIPGMILEGVITNVTNFGAFVDVGVHQDGLIHISALSDKFVSDPREVVKAGDIVKVKVMEVDLQRKRIGMSMRLNDEPGAEKPTRQSRPQADRRQENRPRSNHSDRNQNNTDSAFGGAFAAAFANAKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1F5</accession>
    <name>D0Z1F5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 9">Serine acetyltransferase</fullName>
            <ecNumber evidence="4 9">2.3.1.30</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">VDA_003369</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>acetyl-CoA + L-serine = CoA + O-acetyl-L-serine</text>
            <dbReference type="Rhea" id="RHEA:24560"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:58340"/>
            <dbReference type="EC" id="2.3.1.30"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-cysteine biosynthesis; L-cysteine from L-serine: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.30" evidence="4 9"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302586.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003369"/>
    <dbReference type="EnsemblBacteria" id="EEZ42336">
        <property type="protein sequence ID" value="EEZ42336"/>
        <property type="gene ID" value="VDA_003369"/>
    </dbReference>
    <dbReference type="GeneID" id="57340181"/>
    <dbReference type="eggNOG" id="COG1045">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1639008at2"/>
    <dbReference type="UniPathway" id="UPA00136">
        <property type="reaction ID" value="UER00199"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009001">
        <property type="term" value="F:serine O-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03354">
        <property type="entry name" value="LbH_SAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045304">
        <property type="entry name" value="LbH_SAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010493">
        <property type="entry name" value="Ser_AcTrfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042122">
        <property type="entry name" value="Ser_AcTrfase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005881">
        <property type="entry name" value="Ser_O-AcTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06426">
        <property type="entry name" value="SATase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000441">
        <property type="entry name" value="CysE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00971">
        <property type="entry name" value="SATase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01172">
        <property type="entry name" value="cysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 12" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 9 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SATase_N" evidence="11">
        <location>
            <begin position="9"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="247"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="252"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR000441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ42336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="273" mass="29322" checksum="B2DF0297E29B25E6" modified="2010-01-19" version="1">MKVCHQHQVWQAIKQEAREQAEQEPMLASFYHATIIKHDNLAAALSYILANKLATPSMPAMAVREVIEEAFAADCMITESAAHDIRAVVERDPAVAMYSIPLLYLKGFHALQGYRVANWLWKQNRVALAVYLQNQISVTCQVDVHPAAKIGQGIMFDHATGIVIGETAVIENDVSILQDVTLGGTGKESGDRHPKIREGVMIGAGAKILGNIEVGEGAKIGSCSVVLNPVPSHTTVAGVPAKIVGRPSSSKPAMDMDQQFNGNAQTFTSGDGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1J5</accession>
    <name>D0Z1J5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">3-dehydroquinate synthase</fullName>
            <shortName evidence="11">DHQS</shortName>
            <ecNumber evidence="11">4.2.3.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">aroB</name>
        <name evidence="13" type="ORF">VDA_003409</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate = 3-dehydroquinate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21968"/>
            <dbReference type="ChEBI" id="CHEBI:32364"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
            <dbReference type="EC" id="4.2.3.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <cofactor evidence="11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="11">Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="11">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 2/7.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.4" evidence="11"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302661.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003409"/>
    <dbReference type="EnsemblBacteria" id="EEZ42376">
        <property type="protein sequence ID" value="EEZ42376"/>
        <property type="gene ID" value="VDA_003409"/>
    </dbReference>
    <dbReference type="GeneID" id="57340140"/>
    <dbReference type="eggNOG" id="COG0337">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1677032at2"/>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00085"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003856">
        <property type="term" value="F:3-dehydroquinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00110">
        <property type="entry name" value="DHQ_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016037">
        <property type="entry name" value="DHQ_synth_AroB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030963">
        <property type="entry name" value="DHQ_synth_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030960">
        <property type="entry name" value="DHQS/DOIS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01761">
        <property type="entry name" value="DHQ_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001455">
        <property type="entry name" value="DHQ_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01357">
        <property type="entry name" value="aroB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8 11" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="10 11" id="KW-0170">Cobalt</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 11 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 11" id="KW-0520">NAD</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="DHQ_synthase" evidence="12">
        <location>
            <begin position="69"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="72"/>
            <end position="77"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="106"/>
            <end position="110"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="130"/>
            <end position="131"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="170"/>
            <end position="173"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="248"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="265"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ42376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="359" mass="38841" checksum="CFB03B6949213DAC" modified="2010-01-19" version="1">MERIDVNLGERSYPISIGAKLFATAALFESSITAKQRVVVISNDTVAPLYAEQIIATLRQISSDVVLLSLSDGEQYKTLDTFNQIMTFLLQGNYGRDVVLVALGGGVIGDIVGFAAATYQRGVDFIQVPTTLLAQVDSSVGGKTAVNHPLGKNMIGAFYQPKAVVIDNHCLQTLPAREFAAGMAEVIKYGIIADYDFFCWLEENLAALQALDNQALSYAIARCCQIKADVVAADEKESGVRALLNLGHTFGHAIEAEMGYGNWLHGEAVSAGTVLAANTALAQGMLTQQDVTRIIRLHERANLPVKAPESMTYDSFMQHMMRDKKVLSGQLRLVLPTAIGSAEVVSDVPHDVLRRVIKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1Q7</accession>
    <name>D0Z1Q7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hypothetical intercellular adhesion protein A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_003471</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial sugar transferase family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303541.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003471"/>
    <dbReference type="EnsemblBacteria" id="EEZ42438">
        <property type="protein sequence ID" value="EEZ42438"/>
        <property type="gene ID" value="VDA_003471"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1215">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2148">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1759731at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003362">
        <property type="entry name" value="Bact_transf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02397">
        <property type="entry name" value="Bac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="301"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="346"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="399"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="domain" description="Bac_transf" evidence="3">
        <location>
            <begin position="394"/>
            <end position="587"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ42438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="592" mass="67395" checksum="BC1373C9AEE5EED9" modified="2010-01-19" version="1">MITLTLLLTFLIIYHHIIYSISLLWLAKDRPQPKDPEHTRATLPSIAFILPVHNEADYIEQKLANILMLDYPADKLSLYIFNDGSDDATLANIAYWETKFKEQGIGLYLNHEEHNCGKVIRLNSLIHQAQQSDFLAFTDASALLSIDALQQAVLQFQSPSIGALTGNYLLQNGGSGEKQYWQWQNRLRFAESELGSVMGGNGAFYIVRSHLVETLPEDTINDDFILPMNVLKHGYKIVFSADINTVEIAPTSQSQDYRRRQRIGAGNLQQLIRCRFILRQKNYGALWLFLSGKGLRTLMPFILIGYFFLTLILTLTGSILGLILFMGQCLGYGLALLPTFGLKNNYLIKLHYFVASYFASLIGMLRYSVGQFKRGWRHIPPIDTYQPQITSGCKRLCDIVLSLLGLGLTLPFWPLIALAIKLNSKGPIFYRQLRVGKIEQDTVDLFEIIKFRTMYHSEKNQADLSWAKKEDPRVTSIGRFLRDTRIDEIPQFINVLRGEMSFIGPRPERPELCGSLQNALPFYLERTAGLKPGLTGLAQVNHGYDNTIEDVKEKIGWDHAYAVTLGSPWQWLKMDCYILIKTIKIMLTRKGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-06-02" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1R1</accession>
    <name>D0Z1R1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative membrane protein of ExoQ family involved in exopolysaccharide production</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_003475</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303552.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003475"/>
    <dbReference type="EnsemblBacteria" id="EEZ42442">
        <property type="protein sequence ID" value="EEZ42442"/>
        <property type="gene ID" value="VDA_003475"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3307">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="754057at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007016">
        <property type="entry name" value="O-antigen_ligase-related"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04932">
        <property type="entry name" value="Wzy_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="69"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="100"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="154"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="201"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="225"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="266"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="360"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="392"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ42442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="440" mass="48986" checksum="C1435AB8382BD184" modified="2010-01-19" version="1">MTRDRQLMIAILLSLAITIGWYFEPLPAIALCLLPLLPWLLTNAFYLCVGFILFSYFRIHEAFPVLIPFKIPQLLALLSLLGLGWQLWLQKAQLHYHPLLAKFLAFVFWIVLCSILGTNRAESFTTLSDSFSKIIIMVFAISWLPQSIKQLNKIPILLIISGLAIATIALDNKFHGIGLVEETRVTIGRDIGSMLGDPNDLSLILLFPFSFCLARFFSTRAWLKIIYLISGGLLLAGIMVTESRGGLLGITSAILTISYIKSRSKVLPLVLSGGGLLLLALIAGISERVSGGSHESGIDESAMGRLFAWEAAFKMALANPITGVGLTNYYNNYFFYSNYWDGKNHAVHSSWFEILAENGFIGLFLFVALITATLKVTHYLRLHYQQTPYQSLAEGLWIGLISFCVSGTFLTQGMTWPFYILLGLIMALDRLTPSSKHQES</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z213</accession>
    <name>D0Z213_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Lipoprotein-releasing system ATP-binding protein LolD</fullName>
            <ecNumber evidence="6">7.6.2.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">lolD</name>
        <name evidence="8" type="ORF">VDA_001860</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell inner membrane</location>
            <topology evidence="6">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.</text>
    </comment>
    <dbReference type="EC" id="7.6.2.-" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298831.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001860"/>
    <dbReference type="EnsemblBacteria" id="EEZ40828">
        <property type="protein sequence ID" value="EEZ40828"/>
        <property type="gene ID" value="VDA_001860"/>
    </dbReference>
    <dbReference type="GeneID" id="57342018"/>
    <dbReference type="eggNOG" id="COG1136">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1181903at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044873">
        <property type="term" value="P:lipoprotein localization to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042953">
        <property type="term" value="P:lipoprotein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015854">
        <property type="entry name" value="ABC_transpr_LolD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011924">
        <property type="entry name" value="LolD_lipo_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24220:SF654">
        <property type="entry name" value="PTHR24220:SF654"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02211">
        <property type="entry name" value="LolD_lipo_ex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1 6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-1278">Translocase</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="6"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="42"/>
            <end position="49"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ40828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="229" mass="25395" checksum="C68342101556C0BD" modified="2010-01-19" version="1">MNNSLLHCHHLRKVYQEAQLETEVLKEVEFSIEDSELVAIVGSSGSGKSTLLHILGALDEPTDGEVFFKGTRLDTLSANKQAKLRNKQIGFVYQFHHLLSDFTATENVAMPLLIGGVSVAEARQRAHDMLELVGLKHRLEHRPSELSGGERQRVAIARALVNKPAIVLADEPTGNLDHKTAVEIYDLMRKLNQESGTAFLVVTHDKELASKLDRCMHMKDGVLTQVEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z227</accession>
    <name>D0Z227_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Chromosome partition protein MukE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">mukE</name>
        <name evidence="8" type="ORF">VDA_001876</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Interacts, and probably forms a ternary complex, with MukF and MukB. The complex formation is stimulated by calcium or magnesium.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
            <location evidence="6">Nucleoid</location>
        </subcellularLocation>
        <text evidence="6">Restricted to the nucleoid region.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the MukE family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298858.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001876"/>
    <dbReference type="EnsemblBacteria" id="EEZ40844">
        <property type="protein sequence ID" value="EEZ40844"/>
        <property type="gene ID" value="VDA_001876"/>
    </dbReference>
    <dbReference type="GeneID" id="57342000"/>
    <dbReference type="eggNOG" id="COG3095">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1412262at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009295">
        <property type="term" value="C:nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030261">
        <property type="term" value="P:chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01802">
        <property type="entry name" value="MukE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042037">
        <property type="entry name" value="MukE_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042038">
        <property type="entry name" value="MukE_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007385">
        <property type="entry name" value="Scp_MukE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04288">
        <property type="entry name" value="MukE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 6" id="KW-0132">Cell division</keyword>
    <keyword evidence="3 6" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0226">DNA condensation</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="209"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="231"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ40844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="249" mass="28392" checksum="5BE4C5A7E2011323" modified="2010-01-19" version="1">MSSTNIEEFMPEKLAKAIANPLFPALDNALRSGRHISSEDLDNHAYLIEFETELSMFYKRYNAELVRAPEGFLYLRPRSTSLIGRSVLSEIDMLVGKVLCFLYLSPERLAHEGIFTNQELFDELVSLADEQKLMKLVTNRATGSDLDREKLYDKVKTSLRRLRRIGMLIPIGENGKFRISEAVFRFGADVRTGDDIREAQLRLIRDGEAVVHQQEPSQSSLLDDQDMTDEADNGQQQLDMSTEEQESNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z242</accession>
    <name>D0Z242_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HTH-type transcriptional regulator MetR</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_001778</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298682.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001778"/>
    <dbReference type="EnsemblBacteria" id="EEZ40746">
        <property type="protein sequence ID" value="EEZ40746"/>
        <property type="gene ID" value="VDA_001778"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="750230at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08441">
        <property type="entry name" value="PBP2_MetR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037406">
        <property type="entry name" value="MetR_PBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="7">
        <location>
            <begin position="2"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ40746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="307" mass="34837" checksum="DAA5CFD9871C72FD" modified="2010-01-19" version="1">MIELKHLKTLTTLRETGSLSATANTLCLTQSALSHQIKDLELRLGCQLFLRKTRPVKFTQEGHCLLTLADEIIPKIFQAETDISDLQQSNSGRLHMAIECHSCFQWLMPALKEYQRHWSNVGLDFSSGFSFEPIPALASGELDLVITSDIQTRSDIHYEPLFDFEMRLIVANHSPLAKLTSITPQDLQSQTIISYPVQKKRLDLVKHFLQPAHIEPRQWKQADNTLMLIQMVSANLGVAALPNWAVDDFAKQGLISSKPLEQGLWRRLFAAVREADKKKPYLQAFFATAKEQCQHHLADIKTTSIHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z250</accession>
    <name>D0Z250_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphate-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_001786</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in the system for phosphate transport across the cytoplasmic membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Periplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the PstS family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001786"/>
    <dbReference type="EnsemblBacteria" id="EEZ40754">
        <property type="protein sequence ID" value="EEZ40754"/>
        <property type="gene ID" value="VDA_001786"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042301">
        <property type="term" value="F:phosphate ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024370">
        <property type="entry name" value="PBP_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011862">
        <property type="entry name" value="Phos-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010916">
        <property type="entry name" value="TonB_box_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12849">
        <property type="entry name" value="PBP_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02136">
        <property type="entry name" value="ptsS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00430">
        <property type="entry name" value="TONB_DEPENDENT_REC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0574">Periplasm</keyword>
    <keyword evidence="4" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="3 4" id="KW-0732">Signal</keyword>
    <keyword evidence="2 4" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5027149409" description="Phosphate-binding protein" evidence="4">
        <location>
            <begin position="25"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="PBP_domain" evidence="5">
        <location>
            <begin position="19"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="274" mass="28651" checksum="F7C816CB40CEB1E8" modified="2010-01-19" version="1">MMKTKLIGAIALAGAMAVSTSAAANETISVVGSSSVSPLMEVFGETYSKANNVTVEVQGPGSSAGIRVAHDGSADFGMSSRSLKTEEEGPSIKEVVIARDGIAVVVNPENPVTNLTKEQVSEIYKGDITNWKQVGGNDQPIVVATRDTASGTRGAFEDIMSLKKKINGIKVSAISQRAQVASGNGQLKTTVANNPFAIGYISLGSVDNTVKPLSIDGHQPSVAAIKSGDYSVQRPFIVVYKDGRPSSQALEFLSWMTSADAQKIVADKGFISVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z256</accession>
    <name>D0Z256_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Tyrosine-specific transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_001792</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298709.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001792"/>
    <dbReference type="EnsemblBacteria" id="EEZ40760">
        <property type="protein sequence ID" value="EEZ40760"/>
        <property type="gene ID" value="VDA_001792"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="935253at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015173">
        <property type="term" value="F:aromatic amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018227">
        <property type="entry name" value="Amino_acid_transport_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013059">
        <property type="entry name" value="Trp_tyr_transpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46997">
        <property type="entry name" value="PTHR46997"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03222">
        <property type="entry name" value="Trp_Tyr_perm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00166">
        <property type="entry name" value="AROAAPRMEASE"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="80"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="120"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="148"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="189"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="218"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="268"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="302"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="326"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="366"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ40760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="392" mass="41460" checksum="DC976B8A30BFB998" modified="2010-01-19" version="1">MNLKLLGSSLIIAGTALGAGMLAIPMVLAQFGLAWGSVLMLIIWLGTTYAALLLLEASIKAGGGLGMNTIARKTLGKGGQIITNGLLYALLVCLLMAYIIGSGDLVKKLAASVNIELTMVQSQVAFTVIAGLIVAAGTAVIDKLNRVLFAIMVVMLALTLFSLVPSITFEHLVDATSSDKVALIKTSSVLFTSFGFMVVIPSLVTYNSDASHKQLRNMVIVGSAIPLVCYLLWLYAVVGNLSAEQLVKFANVSELIAALSPKFSGINAILSTFTGLALLTSFLGVAMALFDQNRDALKQNRAVTYVVTFILPLIGALFAANHFLAVLGYAGLILVFLAIFVPMAMTIKLRKVEALEQDNHKELAMCYTAGGGQIAMMLSLVFGCFLIGAQII</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z269</accession>
    <name>D0Z269_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Lipid A biosynthesis lauroyltransferase</fullName>
            <ecNumber evidence="8">2.3.1.241</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Kdo(2)-lipid IV(A) lauroyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">lpxL</name>
        <name evidence="9" type="ORF">VDA_001931</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>alpha-Kdo-(2-&gt;4)-alpha-Kdo-(2-&gt;6)-lipid IVA + dodecanoyl-[ACP] = dodecanoyl-(Kdo)2-lipid IVA + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:28442"/>
            <dbReference type="Rhea" id="RHEA-COMP:9644"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="ChEBI" id="CHEBI:60365"/>
            <dbReference type="ChEBI" id="CHEBI:61524"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:65264"/>
            <dbReference type="EC" id="2.3.1.241"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Bacterial outer membrane biogenesis; lipopolysaccharide biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8">Glycolipid biosynthesis; KDO(2)-lipid A biosynthesis; KDO(2)-lipid A from CMP-3-deoxy-D-manno-octulosonate and lipid IV(A): step 3/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell inner membrane</location>
            <topology evidence="8">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the LpxL/LpxM/LpxP family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.241" evidence="8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298958.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001931"/>
    <dbReference type="EnsemblBacteria" id="EEZ40899">
        <property type="protein sequence ID" value="EEZ40899"/>
        <property type="gene ID" value="VDA_001931"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1560">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1106624at2"/>
    <dbReference type="UniPathway" id="UPA00030"/>
    <dbReference type="UniPathway" id="UPA00360">
        <property type="reaction ID" value="UER00485"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008913">
        <property type="term" value="F:lauroyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036104">
        <property type="term" value="P:Kdo2-lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009103">
        <property type="term" value="P:lipopolysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd07984">
        <property type="entry name" value="LPLAT_LABLAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01942">
        <property type="entry name" value="Lipid_A_LpxL_LpxP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004960">
        <property type="entry name" value="LipA_acyltrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011920">
        <property type="entry name" value="Lipid_A_LpxL_LpxP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30606">
        <property type="entry name" value="PTHR30606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03279">
        <property type="entry name" value="Lip_A_acyltrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF026649">
        <property type="entry name" value="MsbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02207">
        <property type="entry name" value="lipid_A_htrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2 8" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0448">Lipopolysaccharide biosynthesis</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="18"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="HXXXXD motif" evidence="8">
        <location>
            <begin position="134"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ40899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="308" mass="35676" checksum="2E552AA197C0C02D" modified="2010-01-19" version="1">MSKFTAPTFRKAFLHPKYWPTLFLVGLMYIISWLPYFIQFRMGQGIGRLAMHFMKKRRHTIERNLELCFPEMSEQERAQLIQENIDNTGLALFETGMAWFWPDLRVERHVQIEGLEHIHKLQAEGRGVLLIAIHSMNLELGARAFGMKTPGVGVYRPNNNPCFDYFQFEGRIRSNKYMIDRKDVKGMLKALAHGELMWYAPDHDYGRRRSTFAPLFAVEKACTTTGTSLLADASHCAVVPFAMIRNTDSGQYTLKIFPELGEFPHNDPDAAAAYINKAIERSIMEAPSQYMWLHRRFKTRPEGEESLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z280</accession>
    <name>D0Z280_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative DnaK-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001925</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298952.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001925"/>
    <dbReference type="EnsemblBacteria" id="EEZ40893">
        <property type="protein sequence ID" value="EEZ40893"/>
        <property type="gene ID" value="VDA_001925"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0443">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="155921at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021030">
        <property type="entry name" value="DUF3731"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="PTHR19375"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12531">
        <property type="entry name" value="DUF3731"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="953" mass="106360" checksum="BB70E22CA44659C7" modified="2010-01-19" version="1">MSSSPRYLVGIDLGTTHTVVAYSPITDDLQTSPTKIFEIDQLIAPGEVARKALLPSFRYHPAKGEMNENELVLPWNQQPVSGDIQSVIIGEFARELGAKVEGRQVVSAKSWLSHPNVDRNDAILPWSSTASKSDVEKVSPVIASASYLNHVRQAWDYHHKDAPLAEQEVVITVPASFDESARALTLEAAKLAGLPKVLLLEEPQAVCYDWYAQNREHADTLLKDLPLLMVCDVGGGTTDLSLIKVGYKDQQLTLDRIGVGDHLMLGGDNIDLALAHVAEQRLHGESKKLSPAALSKLIQQTRRVKEQLLSGQAPDSAKVTLLGSGSRLIGGAKSIELTRQEVHDIALDGFFPLTSFDDQPNQRQAAVVEFGLPYAADPAISKHLAQFIELHSTVCRNAFAEYNEHAETPINIAENKPAIPMAVLLNGGVFNSPLLSERTLTLFSNWREDAVTELKNPHPDLAVALGAVAYAKARHGAQLKIGGGSARAFFLVIGQNNEHKQGICLLPKGIEEGTEVALKHRKFALTLGEPVRFNLVSTTDDNTAQAGELIELIGDSFITLPPFIATLDSDTDRSELAANQKDREEVTLACQLTEVGTLQIECVSISDSNKRWKVEFAIRKDLARLDRQDSQSTLAESELPPRMTDAVDAIKKVYGGSKNSDNNAVKTLRNDLEKMLGNRDSWETPCLRELASALLESRKRRRRSDLHERTWLKLAGFTMRPGFGYPADDFKMEQIWNMYQQGIQFADNPQTWCDWWTFWRRVAGGLSQEQQLVIYHDIAKYINPVATRDSKLAKELQERSYEEMVRLAASLEHLPFQNKLQLIEWLFGRLQKSQHAQAHWWAIGRIATRTPFYGHIHNLLSAEHIAYCLPELMEFDWRKESYIGFAAVMMTRMTGDRTLDVNDELRQQVIDKLKASRAPESWIQMVSEIKELTEAETKRVFGDALPSGLRLIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z291</accession>
    <name>D0Z291_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transglycosylase Slt family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_000542</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell outer membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000542"/>
    <dbReference type="EnsemblBacteria" id="EEZ39522">
        <property type="protein sequence ID" value="EEZ39522"/>
        <property type="gene ID" value="VDA_000542"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4623">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1444566at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008258">
        <property type="entry name" value="Transglycosylase_SLT_dom_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01464">
        <property type="entry name" value="SLT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00062">
        <property type="entry name" value="PBPb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019918" evidence="6">
        <location>
            <begin position="24"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="domain" description="PBPb" evidence="7">
        <location>
            <begin position="46"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ39522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="483" mass="55682" checksum="77F2E9D4E2CCB06A" modified="2010-01-19" version="1">MKKVMQFFALILMASSLSLSTYALELSPLTSEPYTGDLAVIEKKKVIRVLVSADLGFYYIEDGQPKGIIAELLAHFEQQLKKEKRPLHIQIIPVTRDQLIPLLIEGYGDLIVANLTITATREKEVSFSDPVLDNISELIVTNKSHPLITEITQLSGQDFWVRKSSSYYRSLLRVNNQLELQQLAPINIHFIDETIQDYELIEMINVGLINATLLDSHKVKIWLSTMPNIQVNEQFPLRYKGEIGWAVRKDSPKFLALINNYIKTVKSGTLMGNVIYNKYLNQHLWLKKFLSPSKIDKAKELSNVFFKFSTEYDFDYLMMMAQGYQESGLEQNKVSYKGAVGIMQVLPSTARDKAVNISNIYNPTNNIHAGIKYMAYLRTYFFSDESIDYQNQVYLSLAAYNAGPGNISKMRRYAKEQGYNPNIWFKNVEVVTRKHIGKQPVVYVKNINRYFIMYKQLVVLKKERRGTVKPFHPPYKYNPISLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2A9</accession>
    <name>D0Z2A9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Multidrug resistance protein NorM</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Na(+)/drug antiporter</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000560</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304724.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000560"/>
    <dbReference type="EnsemblBacteria" id="EEZ39540">
        <property type="protein sequence ID" value="EEZ39540"/>
        <property type="gene ID" value="VDA_000560"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0534">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="216729at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006603">
        <property type="entry name" value="DinF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="58"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="94"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="169"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="196"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="257"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="281"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="320"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="352"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="386"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="412"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00030855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="449" mass="48780" checksum="0FF6E6460D6E31A7" modified="2010-01-19" version="1">MRSSSQQSEHFPGLARQLFTMTWPMLFGVLSLMSFQLVDSAFIGQLGVLPLAAQGFTLPMGMVVIGLQVGLGIATTALISRVIGANEIQRAKQLGGLVVATGAVGVFLICLLIWAIREPILQLLDAPANVYPVIQDYWPVWLGSTWVGAMLYFAYSLCRANGNTMLPGVMMMITSVLNMVLDPLFIFKFGLGINGAAWATIASFSLGMLIVFPLVMKRQWMSFNWHGLDIIYSIKELGHIMAPAMLSQLLPPVSSMVATKLVAGFGASAVAAWAMGSRLEFFSIVTVLALTMAMPPMVGRMLGSKEIAKIKALVSIAVRFVLVWQLVIAVILWLVAPYLVTLLTPEQSVSSILLIHLTWVPISLGSLGICMLMVSICNALALPMRALVISGLRLFVCFLPLLWLGAKLAGLHGLFVGAMLGNFAAGIMAWVFYQQGIKKVKIKYCDRHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2H2</accession>
    <name>D0Z2H2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000623</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304897.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000623"/>
    <dbReference type="EnsemblBacteria" id="EEZ39603">
        <property type="protein sequence ID" value="EEZ39603"/>
        <property type="gene ID" value="VDA_000623"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1661500at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="302" mass="33985" checksum="64C7AA3500F980EF" modified="2010-01-19" version="1">MFNLIKIFLKVVEVGSFSKTGQILNMAPSSIARNIDQLEKELCVTLFHRTTRQLTLTDEGQDFYQGATELIHNADALFNQTKKQNQHPQGTIRISVFESFGRQWISPLLPKFLAQYPEVKVEIELENRMVDINSENIDLGIRIGRPADSGLHARMLLPNQTWLCASPTYLANSEPLNCPHDLENHNCLLLNNDRQKVYWYFNNGKQCLRVSVAGNITSKGGTPLVEAAVAHGGVVLMSNWMMVDLVKEGKLIRCLPNWHSSMHEGSSGEIYAVYSGSKFPRPALRAFIDFLVAEINNIDLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2H5</accession>
    <name>D0Z2H5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PlsC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000626</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304906.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000626"/>
    <dbReference type="EnsemblBacteria" id="EEZ39606">
        <property type="protein sequence ID" value="EEZ39606"/>
        <property type="gene ID" value="VDA_000626"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0204">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="421137at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PlsC" evidence="1">
        <location>
            <begin position="92"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="369" mass="41989" checksum="12D343DDA1A40CF3" modified="2010-01-19" version="1">MPTNNDIYKEIRPYNDDEVSAAIARLIDDKEFINAILKYRFPQASGMFGWLLIPLIKRVLIKKWSNVKTVEEIQHHVAKYMQGTLDNSCDGVTWSGLDKLDPNQSYLFVSNHRDIAMDPAMVNWALFHENFNTVRIAIGDNLLKKPCATELMRLNKSFIVKRSVKAPREMMKALGLLSGYISHSLETGHNIWIAQKEGRAKDGNDRTDPALMKMFFMEGRKRKEAFSEFMPKLNIVPVSISYENDPCDAAKAHELYQIQSHGSYEKGEFEDIDSIIKGIVGYKGRIHIAFGDVITQPFETPDELAEEIDRQITKNYHLFPANYIAADIEDGSVTESEIAKFNEKLATLSIGEADLLKKMYAYPAKKKLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2R7</accession>
    <name>D0Z2R7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Aspartoacylase</fullName>
            <ecNumber evidence="7">3.5.1.15</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_000718</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the AspA/AstE family. Aspartoacylase subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.15" evidence="7"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305147.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000718"/>
    <dbReference type="EnsemblBacteria" id="EEZ39698">
        <property type="protein sequence ID" value="EEZ39698"/>
        <property type="gene ID" value="VDA_000718"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2988">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="632656at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019807">
        <property type="term" value="F:aspartoacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00704">
        <property type="entry name" value="Aspartoacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016708">
        <property type="entry name" value="Aspartoacylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007036">
        <property type="entry name" value="Aste_AspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04952">
        <property type="entry name" value="AstE_AspA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018001">
        <property type="entry name" value="Aspartoacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="active site" evidence="5">
        <location>
            <position position="166"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="17"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR018001-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR018001-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="297" mass="33734" checksum="19D57C4C503DE5B6" modified="2010-01-19" version="1">MSSIKRVAIVGGTHGNEFSGIYLLKKWQQQPQSISRPSFCSEMVFANPKAHQENKRYLDHDLNRQFGLADLNNPDLTSYEQCRAKAMNQQLGPKGNAQTDFIIDLHNTTSNMGPSLILLQSDEFNRKMGAYIKCKMPETVVEFEDYSSVDEHHFVSSIAKQGVIIEVGPQPQSVIRQDILDWMEALTQHVLDYVHLSNINALPELPETYEAFQYSETLTLPVNEKGERIGMVHKDVQDADFKPIYNGSAIFTLFNGEIITWDGDYEAYPHFINEAAYYDNNLAMSLARKITVKTSDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2W7</accession>
    <name>D0Z2W7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">Cysteine desulfurase</fullName>
            <ecNumber evidence="4 7">2.8.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_000768</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>[sulfur carrier]-H + L-cysteine = [sulfur carrier]-SH + L-alanine</text>
            <dbReference type="Rhea" id="RHEA:43892"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="EC" id="2.8.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 6">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.7" evidence="4 7"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305292.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000768"/>
    <dbReference type="EnsemblBacteria" id="EEZ39748">
        <property type="protein sequence ID" value="EEZ39748"/>
        <property type="gene ID" value="VDA_000768"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0520">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="446447at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031071">
        <property type="term" value="F:cysteine desulfurase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006534">
        <property type="term" value="P:cysteine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06453">
        <property type="entry name" value="SufS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020578">
        <property type="entry name" value="Aminotrans_V_PyrdxlP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010970">
        <property type="entry name" value="Cys_dSase_SufS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01979">
        <property type="entry name" value="sufS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00595">
        <property type="entry name" value="AA_TRANSFER_CLASS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_5" evidence="8">
        <location>
            <begin position="23"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ39748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="405" mass="45331" checksum="CCEE36AE780A2F3E" modified="2010-01-19" version="1">MIESPWRKDFPIFQQLDKENYRYLDSAATAQKPQIVLDIMDKFYRYDNAAVHRGIHRLSARATDQMELIRERVAQFIHAPSENNIVFTKGTTEAINLIANSYLPTFAQEGDEIIISELEHHANIVPWQMLAQKLGLKIKVWRLADNNRGLCLDAFRELLTEKTKLVAISQLSNVLGTVQPIKEAICMAHQVGAAVMVDGAQGIMHQQTNVQELGCDFYAFSAHKLYGPTGIGALYIASKWLQQLPPWEGGGAMIDKVDLFSKTSYQAAPWRFEAGSPNVAAIMGFGAAIKYVTQIGLSQIQDYEKQLISYMSQQFSDIDNVELYGNGKNRHGVLSFNLTPHHAFDVGSFLDQYGIAIRTGHHCAMPLLKRLDQAAVCRASIALYNNAEDIDRLVASIKRTQMLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z342</accession>
    <name>D0Z342_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">McrB-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000843</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305504.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000843"/>
    <dbReference type="EnsemblBacteria" id="EEZ39823">
        <property type="protein sequence ID" value="EEZ39823"/>
        <property type="gene ID" value="VDA_000843"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1401">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="489714at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011704">
        <property type="entry name" value="ATPase_dyneun-rel_AAA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07728">
        <property type="entry name" value="AAA_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="292"/>
            <end position="685"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="820" mass="94096" checksum="CA6D596E7E2BA0BF" modified="2010-01-19" version="1">MAIYCGNNNSTYLIENANEFKEKCLIQGKSLFTEHSVWNSSTNQELIDYFVENLDEGDGDFFEKLETQLADASPEAKVLVSEMLWLMFLCPSNTGPESKRNSIERVFSWSGYEVNTKSRQRFLSDKALTGIGSAGTAYNTLRWRELVYVIRLVEALLKLSDLERKELLKDVERLPQWLESIPENGTRQFRHMFLYLLFPEAHERIFGNTDRKSILTTLADISSAQYNRMHTKDADAKLLALRQLFEAEYGTQELDYYVEPLRSKWKEPKSLSTNEVNDTVLEYSVKSNDKPQPLNAILYGPPGTGKTYNSINKALEIVDPEFYHQHNDDRVAIKKRFDELLNSNRIGFVTFHQSFSYEDFVEGLKATTENNQVNYEIEDGIFKRLCESARAKSTVKEDQDHVDISGRKIWKMSLGDIAGNDAFIYQQCVDNGYVLLGYGDDINFKQASDRKQVAQIYRDNEVVIESENNNYSVTSVNKFKNEMAIGDLIVVSDGNRKFRAIAEITSDYYFDDSAVDDVGYSQARKVTWRRVYEPSLPVDELFKKNLSQMTLYRLYDSTIDTEKLQAILQGCDEASNVASGHTIVSKRMSPSNQASSDKRVLIIDEINRGNISNIFGELITLIEPSKRAGAKEALSVKLPYSKEMFSVPDNLHIIGTMNTADKSLAQIDIALRRRFQFEEMMTNYELLAEIPLIDGIDIEQIVRVINKRIELLYDREHTIGHSFFLSLKDNPSIEHLAEIFELQILPLLEEYFFENWERVAMVLGDHLKTDEGLRFVVEQFDANEIAQLMGDDWDQEGIQPYVRNDHAFKAAAAYIGIYNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z387</accession>
    <name>D0Z387_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cystathionine beta-lyase</fullName>
            <ecNumber evidence="6">4.4.1.8</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_000888</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + L,L-cystathionine = L-homocysteine + NH4(+) + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:13965"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:58161"/>
            <dbReference type="ChEBI" id="CHEBI:58199"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 5">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <dbReference type="EC" id="4.4.1.8" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305638.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000888"/>
    <dbReference type="EnsemblBacteria" id="EEZ39868">
        <property type="protein sequence ID" value="EEZ39868"/>
        <property type="gene ID" value="VDA_000888"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0626">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="637281at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004121">
        <property type="term" value="F:cystathionine beta-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00614">
        <property type="entry name" value="CGS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006233">
        <property type="entry name" value="Cys_b_lyase_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43500">
        <property type="entry name" value="PTHR43500"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001434">
        <property type="entry name" value="CGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01324">
        <property type="entry name" value="cysta_beta_ly_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00868">
        <property type="entry name" value="CYS_MET_METAB_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="4">
        <location>
            <position position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR001434-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ39868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="400" mass="44525" checksum="8AEB35F6D5A4E59B" modified="2010-01-19" version="1">MTENKGLHTKIITAGRAKKWTQHLVNTPVSRASTVVFDSVKEMKEATANRGNKSLYYGRRGTNTHFAFQEAMTELEGGVGCALFPCGAAAITNSILAFVKAGDHILMVDGVYEPTRDFCDKVLARMGVETTYYDPLIGDELRELIRPNTSVLFLESPCSITMEVQDVPKLASIAHEHDMVVMLDNTWASPINFQPFDHGVDISIQAATKYIVGHSDVMLGTATANERCWSQLQEQSYLMGQCTSPDDIYLAARGLRTLGVRMKQHEESALKVAHWLSQRPEVDHVRHPAFESCDGNAFFKRDYLGSNGLFSFVLKYGDISSVNAMLDSMKHFSMGYSWGGYESLILANHNINSIRAVDKKEFSGAIIRLHIGLESVEDLISDLNDGLEVLNKKYKQQNIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z394</accession>
    <name>D0Z394_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000895</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305657.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000895"/>
    <dbReference type="EnsemblBacteria" id="EEZ39875">
        <property type="protein sequence ID" value="EEZ39875"/>
        <property type="gene ID" value="VDA_000895"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1670">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1538300at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="12"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="182" mass="20742" checksum="1231C27641306D23" modified="2010-01-19" version="1">MSLHQPLLETPRLLLRPLELSDSTKIQHLAGDFSIANKTLSVPHPYHDGMAGQWIGVHLAGWQAKTSIMFAIVEKQSNKLIGCVGLEHIKDNHAQIGFWIGVPYWGNGFCTEAALAVKEYASRDLELHYLYARHLHREPSSGKVMKKIGMEYKNSVERLHNNHKEQLDYYECVLTKSHIETK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3G6</accession>
    <name>D0Z3G6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000967</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000967"/>
    <dbReference type="EnsemblBacteria" id="EEZ39947">
        <property type="protein sequence ID" value="EEZ39947"/>
        <property type="gene ID" value="VDA_000967"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LysR_substrate" evidence="1">
        <location>
            <begin position="2"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="223" mass="25319" checksum="0C1D6D7D9898CFFD" modified="2010-01-19" version="1">MRGTLKISAPRDIGKQYISPILSEFSQLYPDVIPYLYLNDNLSNLAESGLDIVIRYGELADSNLISRKLASSRRVLCASPQYLSKKGTPITPQDLAQHDCLALVRSNEELKTWHFQDEEQHNVVTVVPKRFSDDGEVIRQWALDGAGIALKSILDVQEDIKQQRLVTVLNGYMKNFNASTSSAGADLNVIYLSRQYQPKRLRLFLAFLIEQFKLRFEGNNINE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3I4</accession>
    <name>D0Z3I4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hydrogenase assembly chaperone hypC/hupF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000985</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HupF/HypC family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000985"/>
    <dbReference type="EnsemblBacteria" id="EEZ39965">
        <property type="protein sequence ID" value="EEZ39965"/>
        <property type="gene ID" value="VDA_000985"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0298">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001109">
        <property type="entry name" value="Hydrogenase_HupF/HypC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35177">
        <property type="entry name" value="PTHR35177"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01455">
        <property type="entry name" value="HupF_HypC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00445">
        <property type="entry name" value="HUPFHYPC"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00074">
        <property type="entry name" value="hypC_hupF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="61" mass="6843" checksum="8B8636AC0D7E5F73" modified="2010-01-19" version="1">MGVQRKVSTHLIAEPIELGDHLLVHVGFAISKINAKEAQESLEMYKLILADMERQELEGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3M6</accession>
    <name>D0Z3M6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Purine nucleoside phosphorylase DeoD-type</fullName>
            <shortName evidence="4">PNP</shortName>
            <ecNumber evidence="4">2.4.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">deoD</name>
        <name evidence="6" type="ORF">VDA_001027</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a purine 2'-deoxy-D-ribonucleoside + phosphate = 2-deoxy-alpha-D-ribose 1-phosphate + a purine nucleobase</text>
            <dbReference type="Rhea" id="RHEA:36431"/>
            <dbReference type="ChEBI" id="CHEBI:26386"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57259"/>
            <dbReference type="ChEBI" id="CHEBI:142361"/>
            <dbReference type="EC" id="2.4.2.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a purine D-ribonucleoside + phosphate = a purine nucleobase + alpha-D-ribose 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:19805"/>
            <dbReference type="ChEBI" id="CHEBI:26386"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57720"/>
            <dbReference type="ChEBI" id="CHEBI:142355"/>
            <dbReference type="EC" id="2.4.2.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homohexamer; trimer of homodimers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the PNP/UDP phosphorylase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.1" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306019.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001027"/>
    <dbReference type="EnsemblBacteria" id="EEZ40007">
        <property type="protein sequence ID" value="EEZ40007"/>
        <property type="gene ID" value="VDA_001027"/>
    </dbReference>
    <dbReference type="GeneID" id="57342489"/>
    <dbReference type="eggNOG" id="COG0813">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1028277at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004731">
        <property type="term" value="F:purine-nucleoside phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009164">
        <property type="term" value="P:nucleoside catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042278">
        <property type="term" value="P:purine nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09006">
        <property type="entry name" value="PNP_EcPNPI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01627">
        <property type="entry name" value="Pur_nucleosid_phosp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004402">
        <property type="entry name" value="DeoD-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018016">
        <property type="entry name" value="Nucleoside_phosphorylase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000845">
        <property type="entry name" value="Nucleoside_phosphorylase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43691:SF2">
        <property type="entry name" value="PTHR43691:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01048">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="SSF53167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00107">
        <property type="entry name" value="deoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01232">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PNP_UDP_1" evidence="5">
        <location>
            <begin position="17"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphate binding" evidence="4">
        <location>
            <begin position="88"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Purine nucleoside binding" evidence="4">
        <location>
            <begin position="180"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Purine nucleoside binding" evidence="4">
        <location>
            <begin position="204"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="205"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="5"/>
        </location>
        <ligand>
            <name>a purine D-ribonucleoside</name>
            <dbReference type="ChEBI" id="CHEBI:142355"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="21"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="25"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="4">
        <location>
            <position position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="236" mass="25764" checksum="27A134AE890EB154" modified="2010-01-19" version="1">MATPHINAEFGDFAETVLMPGDPLRAKFIAETYLEDAKEVCNVRNMFGYTGTYKGHKISVMGHGMGIPSCSIYVHELIKDFGVKNVIRIGSCGAVHDDVKLMDVIIGMGASTDSKVNRIRFNNHDFAAIADFHLLETAVSQARSQNVPVRVGNVFSADLFYSPEVDLFDKMEKLGILGVDMEAAGIYGVAAELGAKALTILTVSDHIKRGEKLSSEDRQKSFNDMMNVALETAVNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3S5</accession>
    <name>D0Z3S5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">N-acetylglucosamine-6-phosphate deacetylase</fullName>
            <ecNumber evidence="7">3.5.1.25</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_001076</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="5">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the metallo-dependent hydrolases superfamily. NagA family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.25" evidence="7"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306159.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001076"/>
    <dbReference type="EnsemblBacteria" id="EEZ40056">
        <property type="protein sequence ID" value="EEZ40056"/>
        <property type="gene ID" value="VDA_001076"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1820">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1026967at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047419">
        <property type="term" value="F:N-acetylgalactosamine-6-phosphate deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008448">
        <property type="term" value="F:N-acetylglucosamine-6-phosphate deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006044">
        <property type="term" value="P:N-acetylglucosamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00854">
        <property type="entry name" value="NagA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003764">
        <property type="entry name" value="GlcNAc_6-P_deAcase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11113:SF14">
        <property type="entry name" value="PTHR11113:SF14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038994">
        <property type="entry name" value="NagA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00221">
        <property type="entry name" value="nagA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="6">
        <location>
            <begin position="49"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="4">
        <location>
            <position position="272"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="215"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR038994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR038994-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR038994-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="384" mass="41536" checksum="8471B2F3688D47DE" modified="2010-01-19" version="1">MRFALHPQRIFTATGIETDRYVIVAGGEIEQITVERPVDCDVIELDNQTLLPGLIDIHIHGRAGSDVMDATEAALQTISDALPQTGVVAWVGTTVTAPWQDILAALEQVRDFTTGSHSGAQLLGSFLEGPYFTEAYRGSHPTTYLKAPTIAELTELQQVAGQSLLRVALAPEYDGAMSAIDWLTERGIKTSVAHTSANFEQVTQAYQAGADCGVHLFNGMLGLHHREPGCCGAVLYHDMLAELIADGIHVHPVMMQLAYRMKGYQKLALITDCMRAGGLSDGEYLLGAQMIQVKQGEARTQDGSLAGSTCSLDQALRNMIFSVGVNEWEAVQMASLVPAQYINKASELGSIAVGKRASFAVVDSDFVIQSTMIDGQWAFKRNAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3U8</accession>
    <name>D0Z3U8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ATP synthase beta chain</fullName>
            <ecNumber evidence="11">3.6.3.14</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">VDA_001101</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.14" evidence="11"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001101"/>
    <dbReference type="EnsemblBacteria" id="EEZ40079">
        <property type="protein sequence ID" value="EEZ40079"/>
        <property type="gene ID" value="VDA_001101"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0055">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1140.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005722">
        <property type="entry name" value="ATP_synth_F1_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024034">
        <property type="entry name" value="ATPase_F1/V1_b/a_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01039">
        <property type="entry name" value="atpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0139">CF(1)</keyword>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AAA" evidence="10">
        <location>
            <begin position="54"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ40079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="372" mass="40602" checksum="977E8C5F915DDFE3" modified="2010-01-19" version="1">MNVLGEPIDECGEIGEETRYAIHRSAPSYEEQANSTALLETGVKVIDLICPFAKGGKIGLFGGAGVGKTVNMMELINNIAKAHSGLSVFTGVGERTREGNDFYYEMKEAGVLDKVSMVYGQMNEPPGNRLRVALTGLTIAERFRDEGRDVLLFIDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKKGSITSIQAVYVPADDLTDPSPATTFAHLDATVVLSRNIAALGLYPAIDPLDSTSRQLDPLVVGTEHYEVARGVQTVLQRYKELKDIIAILGMDELSEEDKQTVSRARKIERFLTQPYHVAEVFTGQPGIFVSLKDTISGFKGLLSGEYDDIPEQAFLYCGGIDEVIEKAKSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z422</accession>
    <name>D0Z422_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Formate hydrogenlyase subunit 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000278</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303924.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000278"/>
    <dbReference type="EnsemblBacteria" id="EEZ39260">
        <property type="protein sequence ID" value="EEZ39260"/>
        <property type="gene ID" value="VDA_000278"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3260">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1904620at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006137">
        <property type="entry name" value="NADH_UbQ_OxRdtase-like_20kDa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006138">
        <property type="entry name" value="NADH_UQ_OxRdtase_20Kd_su"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01058">
        <property type="entry name" value="Oxidored_q6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01150">
        <property type="entry name" value="COMPLEX1_20K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxidored_q6" evidence="2">
        <location>
            <begin position="49"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="287" mass="30987" checksum="B052F141F777698D" modified="2010-01-19" version="1">MKGIKQLVGTAHTQTVPVELPPHSQKLKDALIKQIRRSAYVYRVDCGGCNACEIEIFAATTPVFDAERFGIKVVASPRHADILLFTGAVTRAMRAPALRAYEAAPDPKIVISYGACGCDGGIFHDLYCVWGGTDKIVPVDVYIPGCPPTPAATIYGFAVALGLLDQKLKSKTHQPDQTKASLRHTGIPLDLKVMIEREARLLAGYVQGQRIADEVIEILANSDSDTVDSNIQTYLEQKDDPRLCEIVHILFNKTMAALTGTGPQASSICSSQCQKTCSSSAQNDLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z435</accession>
    <name>D0Z435_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000291</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303958.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000291"/>
    <dbReference type="EnsemblBacteria" id="EEZ39273">
        <property type="protein sequence ID" value="EEZ39273"/>
        <property type="gene ID" value="VDA_000291"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5034326">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1699821at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="126" mass="14382" checksum="7D18C3C9B7FA3172" modified="2010-01-19" version="1">MTNFQYYFHKLPCYNCKKTKVDTDLGWLTAGMKDEILEQVKVLMNEGNIEPDFSVKVTCTEDEARDYLLLNYYGYSDDELKHGHIESEDAEEVADEVSEHMTAEGVAVFDHEIALQSCIDCGVLDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-06-02" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z463</accession>
    <name>D0Z463_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_000319</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304031.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000319"/>
    <dbReference type="EnsemblBacteria" id="EEZ39301">
        <property type="protein sequence ID" value="EEZ39301"/>
        <property type="gene ID" value="VDA_000319"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5001">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAS" evidence="1">
        <location>
            <begin position="178"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="2">
        <location>
            <begin position="249"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="4">
        <location>
            <begin position="338"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="3">
        <location>
            <begin position="478"/>
            <end position="733"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="734" mass="82584" checksum="C2557C1279B342FD" modified="2010-01-19" version="1">MTLISKMGFTHWSTRLLSEFNRSDLSKMSLVAYCKAVCDSVIKEENICGASFDLFEDVTGQFVNLTRSGNYSNDFSLPVSLVFKHFSMDFSQCQRKPFIMTLDPNSQDDLSVFPLSTKSIALFPIINTDRIIGYFSICASNLNAFHQVEMEAIYSLMSYFVLLYTLKSTSVNQSPSITWDKLSLAINQCSETIVITDLRGNIEYVNDEFERSTGYKAQDVLGKNPRVLQSGKTTRDTYRDLWKTLRSGERWQGEFINRKSCGSEYVEFARITPIRQENGDGSVTHYMAIKKDITETKATRNQVEKLAYYDSLTGLPNRALFLKRLKKLLNDDAGSSQLPLSLMFIDLDHFKEINDTQGHDHGDCLLQTIGQTIRSILESHHTLARLGGDEFVVIAPDTDAEQAQTIAYKLHQTISQPIPLKGQNISVGASIGITVCEKQGPSVSTLLKQADIAMYRAKAQGNGFCLYLPEMELALNRKITLARKLLSAIRQDKLALNFQPFIDLNSQQCVGAEVLLRWFDDDLGWISPAEFIPLAEERHLVSEISNWVIRHTCRQMLSWQNQGYVLNGRLSINISAQEIGQESCAQRIIQLVEEEGISPYLLDIEITESAVVVCPHLAEDDINQLAKAGFTVSIDDFGTGYSSLSKLKHFSVNKLKIDRSFINELLIDDANRKIVTAIIAVAKSLCLQLVAEGVEDKQQEALLSEMGCDFAQGYLYTKPLANDQFARYWLKTNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4B3</accession>
    <name>D0Z4B3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000369</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304173.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000369"/>
    <dbReference type="EnsemblBacteria" id="EEZ39351">
        <property type="protein sequence ID" value="EEZ39351"/>
        <property type="gene ID" value="VDA_000369"/>
    </dbReference>
    <dbReference type="GeneID" id="57343250"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="846433at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="5"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="295" mass="33959" checksum="FEA235465985A3EE" modified="2010-01-19" version="1">MRVIPPIKAVINFEAAARLQSFKLAAEELCVTPGAVSHQISTLEEFIGQKLFQRQNRSIKLTNAGLRYYERTSSILSDLEQATTDLGRIHKQKQLKMALPPALLNKWLLPKFHLIANELEGVNVTFIDTLDYLDLQRDEIDISIRYGFEKPDGLYSDLLFKEDMIAVCAPHYHEQHFDKLSQSFLESSTLIYTTNRLVQWDLVLHHYGMKPLKWQRKLIFQNSIQAIDAAVLGCGVAFINRRLVEELLVQGQLVEAIQVNIDPDKVPSYYLVSSYENMQDENIAKFYQLLKKLCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4C3</accession>
    <name>D0Z4C3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Endoribonuclease L-PSP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000379</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RutC family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304200.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000379"/>
    <dbReference type="EnsemblBacteria" id="EEZ39361">
        <property type="protein sequence ID" value="EEZ39361"/>
        <property type="gene ID" value="VDA_000379"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0251">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1850770at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006056">
        <property type="entry name" value="RidA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11803">
        <property type="entry name" value="PTHR11803"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="SSF55298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00004">
        <property type="entry name" value="TIGR00004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="128" mass="13909" checksum="CD73264D92A7583F" modified="2010-01-19" version="1">MKTQIHTDSAPAAIGPYSQALAFQDIVFTSGQLPLDPETMAFAEGDIKEQARQSLTNLKAILEQAGASMDTVLKTTCFLSDMENFAAFNEVYTEFFGTEIAPARSCVQAARLPKDALVEVEAIAFIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4D0</accession>
    <name>D0Z4D0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hypothetical multidrug resistance efflux pump</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000386</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304221.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000386"/>
    <dbReference type="EnsemblBacteria" id="EEZ39368">
        <property type="protein sequence ID" value="EEZ39368"/>
        <property type="gene ID" value="VDA_000386"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1566">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="757027at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="2">
        <location>
            <begin position="43"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="349" mass="38343" checksum="D94EA7B10B075FD8" modified="2010-01-19" version="1">MKEKIYQTILYSVVGCALAFSAFLLISDNVAPFTTQATLYKPVANIAPEVSGVITHVNVENGENVQQGQILFTIDPKPYQIAVAQAEAELKQAQDSNLAMWQQLASAKEGLTQKNSQWHNALNTLHRYQALNKKGLTTRQELDNAQTTEQVAKSAIAAAKAEVLRIKAQLAGDKNSAAVELALAKLQQAELNLTHTKVVAQTSGTISNLQIETGTYVKSGTPVLFLVNNNDSWLSADFNEKGISHLQPNTQVSISFDALPGQVFTGVIENKDDAIYDANNPETRLSTVANDTRWIREQQKIRTRIDVQQLDTNLISGARASVVVKNGNPIIDAISRIWIHCVALFRYVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4D6</accession>
    <name>D0Z4D6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Galactosyl transferase GDP-mannosepyrophosphorylase phosphomannomutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000392</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304237.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000392"/>
    <dbReference type="EnsemblBacteria" id="EEZ39374">
        <property type="protein sequence ID" value="EEZ39374"/>
        <property type="gene ID" value="VDA_000392"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0367">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="859908at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="563" mass="64536" checksum="748947C52DD772CF" modified="2010-01-19" version="1">MSIIAGFFLLEPDKTDPEFVDGIEDLIRTHISRRATDTRYEYTDGYLYLCRVDLGCYHEASWAEDHTRLTTILGHTFISASLTQDTNHLFSHGVSARSLEKADGTYTALQYDKIERELTVCFDSLSLRPLYYLQINQMVIFSSCQRIYPKLGLNLTVDMNAISEIATIGFPLAGKTRYQDVRSVQAGEQLTINLSGISIKTGFNWGDYQPQLLNEKSALSLFEQTFSSVLNKYRKSDNNMVSTLSGGLDSRVLVEALHQRGTVIECINFSRANSQDDIYASQYAHTRHIRLRQIEVEDTQAVSVEYRLGQYWRRLNFSFYQQVERPRLFWSGNGGSVCLGMVYFSDDIAKACESGSVEAVADAYIDLQQAYIPKRLVKGAAELQQQLRKTIIACLTKYANVDLFKAYQLFLWENDQHQHLVSAYEDMDIYRLDFYLPFYAKSLLDVIHRIPPQLLLKHQFYMTWVRTYLPDALCSPWQVYPGHEPCDLADNIIQAPISQWQLKRPWSAKMKLIKTGISAFFDTQNTFYHRHYLGANCILTALGLYNGSATLNVINRMNQALSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4Q3</accession>
    <name>D0Z4Q3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Autoinducer 2-binding periplasmic protein LuxP</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000511</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000511"/>
    <dbReference type="EnsemblBacteria" id="EEZ39491">
        <property type="protein sequence ID" value="EEZ39491"/>
        <property type="gene ID" value="VDA_000511"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1879">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025997">
        <property type="entry name" value="SBP_2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13407">
        <property type="entry name" value="Peripla_BP_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peripla_BP_4" evidence="2">
        <location>
            <begin position="2"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="266" mass="28079" checksum="8BEB63A4B5D9FBB6" modified="2010-01-19" version="1">MAMVVSTLNNPFFVTMKDGAEAKAKELGYELIVLDSQNDPSKELSNVEDLTVRGVKAILINPTDSDAVSNAIRIANRSKIPVLTLDRGASRGDVVSHIASDNVAGGEMAGKFIMEKVGQKAKVIQLEGIAGTSAARERGQGFMDAVKKYDMDLLASQPADFDRTKGLNVMENMLAANPDVQAVFAQNDEMALGALRAIQASGKNVLVVGFDGTEDGIAATKRGKLGATIAQQPDLIGSLGVETAAKVLKGETVEKNIPVPLKVITQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4R6</accession>
    <name>D0Z4R6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">SM-20-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_000524</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000524"/>
    <dbReference type="EnsemblBacteria" id="EEZ39504">
        <property type="protein sequence ID" value="EEZ39504"/>
        <property type="gene ID" value="VDA_000524"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3751">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0847">Vitamin C</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="7">
        <location>
            <begin position="124"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ39504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="237" mass="28303" checksum="BD71F9D7CF1196D5" modified="2010-01-19" version="1">MHYFFHLNNKNFDLLTCYKTFITRKKTIINGTKIMNKIDKMLDALATEGYFLWDDFLNNEQVEHLRQCIPDNWKKARIGRNDEIMRESSIRSDKIQWLTPEQGWPIQDYLERMEVIRREVNQNFFLGLFEYEAHFAKYEQGDFYQKHLDCFKGNENRRLTTVFYMNESWSPEDGGELVVYDLNDQKITTIAPKSGRLFIFLSEKFPHEVLPTNAERFSIAGWFRINGVKDNQLDIAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4S9</accession>
    <name>D0Z4S9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ATP-dependent RNA helicase DbpA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_000537</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the DEAD box helicase family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000537"/>
    <dbReference type="EnsemblBacteria" id="EEZ39517">
        <property type="protein sequence ID" value="EEZ39517"/>
        <property type="gene ID" value="VDA_000537"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0513">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005580">
        <property type="entry name" value="DbpA/CsdA_RNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03880">
        <property type="entry name" value="DbpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4 7" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="5">
        <location>
            <begin position="9"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="6">
        <location>
            <begin position="190"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="437" mass="47822" checksum="49E19C977C9BAAEE" modified="2010-01-19" version="1">MTPIQAQSLPIILAGQDIIAQGKTGSGKTAAFGLGLLNNLNVKRFRVQTLVLCPTRELADQVAKEIRRLARAIHNIKVLTLCGGMPFGPQIGSLEHGAHIIVGTPGRVEEHLRKGNLSLDNLNTLVLDEADRMLEMGFQDAIDAVIDCAPKQRQTLLFSATYPTQIASIANSIMNKPAMVKVEATHDNSSISQHFYKVDNNEERMDAVRLLLAKHHPESAVIFCNTKREAQEVADTLVDEGFSALALHGDLEQRERDRTLVRLANKSCSILVATDVAARGLDIDALDAVINYHLARDTEVHVHRIGRTGRAGSKGIACSLFSDKEHYKVALLEDYLDRPISGEALPDQSVLNQPPYRPAMVTLLIDGGKKQKVRPGDILGALTGGDKSIQGSQVGKIHIFDYCAYVSVQRDIAKAALKKLENGKIKGRNFRARMIRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4Y2</accession>
    <name>D0Z4Y2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000215</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306629.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000215"/>
    <dbReference type="EnsemblBacteria" id="EEZ39199">
        <property type="protein sequence ID" value="EEZ39199"/>
        <property type="gene ID" value="VDA_000215"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3209">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1521871at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018931" evidence="1">
        <location>
            <begin position="20"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="331" mass="37486" checksum="6343C535608FB1C0" modified="2010-01-19" version="1">MKKLLPMTILLALSSAANASQDSVFPDFIDPSLTACTDIRLSRLVRKGTGEVADVAVGQYEYNANNKITKREYLDSTFTYEYNDDGTLNKASALRKPDGPGIIIRHTNESFISEYTYNNGRVASETKKVFSASDTNLDGEPEATYTITYHFDDQGKLIRRNQVNSSNNNNVFYTYTYNQQGQLSKINEERKSGNVIADRNIILLSYNTDGEIIKAIHKKPLLGNVDDVPPVIKTVNISYYDSNDDVYPFHYVDPVKEWKIDRDYFGLSYHQIQSITTTEADKVTTANYTYTDTNDDFLPDTFTVNLKITKGEQLLYSVNQPYDLLYPAPAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4Z2</accession>
    <name>D0Z4Z2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000225</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39209">
        <property type="protein sequence ID" value="EEZ39209"/>
        <property type="gene ID" value="VDA_000225"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3316">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032874">
        <property type="entry name" value="DDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13610">
        <property type="entry name" value="DDE_Tnp_IS240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_IS240" evidence="1">
        <location>
            <begin position="1"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="155" mass="18020" checksum="35CAF2391AE80E02" modified="2010-01-19" version="1">MDETYIKIKGKWWYYYRAVDKYGDIVDFYLSQTRDEKSAQAFLRKAIRTNGLPDQVVIDKSGANARALHHMNVKLWKSVVFMLNLIEIIDVKYLNSIVEQSHRPIKQKMYQALGWKSVEGASATMSGQEVWTQIKRGQVGELSLPVWERFYALIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4Z5</accession>
    <name>D0Z4Z5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000228</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306666.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000228"/>
    <dbReference type="EnsemblBacteria" id="EEZ39212">
        <property type="protein sequence ID" value="EEZ39212"/>
        <property type="gene ID" value="VDA_000228"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3316">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1667004at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032874">
        <property type="entry name" value="DDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13610">
        <property type="entry name" value="DDE_Tnp_IS240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_IS240" evidence="1">
        <location>
            <begin position="70"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="228" mass="26921" checksum="9F4132E2D494A542" modified="2010-01-19" version="1">MQFTGYHFPYDIILQAVRYYVAYKLRYHDIEEIFAERGIRVDHATINRWVIRFAPLIEQNARTSKYYVSSSWRMDETYIKIKGKWWYYYRAVDKYGDIVDFYLSQTRDEKSAQAFLRKAIRTNGLPDQVVIDNSGANARTLHHMNVKLWKSVVFMLNLIEIIGVKYLNNIVEQSHRPIKQKMYQALGWKSVEGASATMSGQEVWTQIKRGQVGELSLPVWERFYALIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z595</accession>
    <name>D0Z595_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000145</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306975.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000004.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39129">
        <property type="protein sequence ID" value="EEZ39129"/>
        <property type="gene ID" value="VDA_000145"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502ZXQR">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1403295at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021316">
        <property type="entry name" value="DUF2913"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11140">
        <property type="entry name" value="DUF2913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="198" mass="22860" checksum="DA6AB833D672049A" modified="2010-01-19" version="1">MSNNPYHALLSDVVDNALLHLYSEVSTSARFVPTIKRNKILVRYLKPKFKSPKYKLVKAELKTMIGIGRNQEGNLEVKLIELNQLANKHRQDTTDAYSLFQLMELLNTEYDFDSKLFNPDVISVADVIYILPDHIEHCFSDDGIQVAPISLFIESERVQELLAAIQDSKLFMAEMTEWNDLKKQAHILLHPIMQKKYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5B0</accession>
    <name>D0Z5B0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cytolysin and hemolysin HlyA Pore-forming toxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000160</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005307016.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000160"/>
    <dbReference type="EnsemblBacteria" id="EEZ39144">
        <property type="protein sequence ID" value="EEZ39144"/>
        <property type="gene ID" value="VDA_000160"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502ZBG7">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1496307at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051715">
        <property type="term" value="P:cytolysis in another organism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00161">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022220">
        <property type="entry name" value="Hemolysin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043080">
        <property type="entry name" value="Hemolysin_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044883">
        <property type="entry name" value="Hemolysin_pre-stem_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016183">
        <property type="entry name" value="Leukocidin/Hemolysin_toxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036435">
        <property type="entry name" value="Leukocidin/porin_MspA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12563">
        <property type="entry name" value="Hemolysin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07968">
        <property type="entry name" value="Leukocidin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00458">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="SSF50370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56959">
        <property type="entry name" value="SSF56959"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018954" evidence="2">
        <location>
            <begin position="24"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B-type lectin" evidence="3">
        <location>
            <begin position="480"/>
            <end position="558"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="603" mass="68046" checksum="C63FFBF55159BCC4" modified="2010-01-19" version="1">MKIRKLYSCILLGLSSLSASAIAEVDNYSTPADVVSILSSVKNPDRIVYINMKQEELSTYDSILEDIINNDKQYIFDLSFDSDEEKANIQKKFKDLMGVKFDSNFIVVTGYKNQLMYTPISDTNDRMISILDHEAKSDDISKFPRALALSSGKVASDQSISLPHVSFYLNVNKEITDQECTFRNSLIWDRGSRSFCKNGNISLIYQVILERSLSFGTNGVATPDAKIVRISLDDNTTGAGIHLNDTLTHKSYWANYQVVSGWAREWSASAIAQDYLFDISTSNEKAQILKTFPRENINSNYNINESSGFTIGVTGGAEVSKDGPKASLQASASYSQSKSLSFNTQDYRVEKNSTSAQNVSFRWAREQYPNSESLLDKWTNPVWSEDYPANLKKVQPLSYASFVPKLDVIYKASPNETGKTQFTIDSSVNIMPLYNRAWFYFYGVGAHQTYYGVDDQPLRRVNKAISFTVDWEHPVFTGGTPVNIQLASFNNKCMDIQNKGIVMTAECDINSKSQSFIYDQYNRYVSATNTKLCLDGESLSELQPCSLKLTQKWLWDGDKLKNSFEDKYLTFDNDTFLLEASLSNKQKLNSSYTRVFDSSTINK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5E6</accession>
    <name>D0Z5E6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000053</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000005">
        <property type="protein sequence ID" value="EEZ39068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005307087.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000005.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39068">
        <property type="protein sequence ID" value="EEZ39068"/>
        <property type="gene ID" value="VDA_000053"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502ZXQR">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1403295at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021316">
        <property type="entry name" value="DUF2913"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11140">
        <property type="entry name" value="DUF2913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="199" mass="22857" checksum="8EF31BBD275FC43A" modified="2010-01-19" version="1">MSNNPYHALLSDVVDNALLHLYSEVSTSARFVPTIKRNKILVRYLKPKLKSPKYKRVKAELKTMIGIGRNQEGNLEVKLIELNQLANKHRQDTTDAHSLFQLMELLDAEHDFDSKLFNPDVISVADVIYILPDHIEHCFSDDGIQVAPISLFIESERVQKLLSAIQDSKLFMAEMTEWNDLKKQAHILLHPINSEKNTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5E7</accession>
    <name>D0Z5E7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000054</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000005">
        <property type="protein sequence ID" value="EEZ39069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005307090.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000005.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39069">
        <property type="protein sequence ID" value="EEZ39069"/>
        <property type="gene ID" value="VDA_000054"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="68" mass="7740" checksum="9FB2014E4803A204" modified="2010-01-19" version="1">MPAFKITYHHDGQVVFEETVFMKTLKTAKKSADCQSPQAVIEISIADLMDRELAERKQGQWADKKNAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5I5</accession>
    <name>D0Z5I5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Type II restriction enzyme PstI (Endonuclease PstI) (R.PstI)</fullName>
            <ecNumber evidence="3">3.1.21.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000003</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.21.4" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000007">
        <property type="protein sequence ID" value="EEZ38996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005307227.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000007.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000003"/>
    <dbReference type="EnsemblBacteria" id="EEZ38996">
        <property type="protein sequence ID" value="EEZ38996"/>
        <property type="gene ID" value="VDA_000003"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0827">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="703278at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009036">
        <property type="term" value="F:type II site-specific deoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041963">
        <property type="entry name" value="BsuBI/PstI_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041454">
        <property type="entry name" value="BsuBI/PstI_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041962">
        <property type="entry name" value="BsuBI/PstI_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009528">
        <property type="entry name" value="Restrct_endonuc_II_BsuBI_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06616">
        <property type="entry name" value="BsuBI_PstI_RE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17728">
        <property type="entry name" value="BsuBI_PstI_RE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BsuBI_PstI_RE_N" evidence="2">
        <location>
            <begin position="4"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="BsuBI_PstI_RE" evidence="1">
        <location>
            <begin position="153"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ38996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="326" mass="37410" checksum="9994FB87F2666E53" modified="2010-01-19" version="1">MREQKLIQAQEILKSLGLPKQQCNDRSAWVFLALANVKPEDNWSVATAPLLPTVNIMEFIRSEYGKDYKPNSRETIRRQTLHQFDQAQVVDRNRDNPARATNSKDNNYSLNQPIIKILHAYPDNNWKELVQEFLNEVPTLQAIYERTINKEKIPVHLPNGNKITLSPGVHNQLHADIVHEFCPRFIGEGGIVLYIGDTASSRNEGGKHMVLETKYLESLNVPPMSHDKLPDVVVYDENRKWLFLIEAVTSHGPVSPKRWVELEEALDGCSVGRVYVTAFPHRDEFRKNAADIAWETEVWIADNPDHMIHFNGDRFLGPHNNKPEIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVJ6</accession>
    <name>D0YVJ6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Na(+)/H(+) antiporter NhaB</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Sodium/proton antiporter NhaB</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">nhaB</name>
        <name evidence="5" type="ORF">VDA_001576</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>3 H(+)(out) + 2 Na(+)(in) = 3 H(+)(in) + 2 Na(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:29247"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298311.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001576"/>
    <dbReference type="EnsemblBacteria" id="EEZ40550">
        <property type="protein sequence ID" value="EEZ40550"/>
        <property type="gene ID" value="VDA_001576"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3067">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="305652at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015385">
        <property type="term" value="F:sodium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01599">
        <property type="entry name" value="NhaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004671">
        <property type="entry name" value="Na+/H+_antiporter_NhaB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43302:SF1">
        <property type="entry name" value="PTHR43302:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06450">
        <property type="entry name" value="NhaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00774">
        <property type="entry name" value="NhaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0050">Antiport</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0915">Sodium</keyword>
    <keyword evidence="3 4" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="148"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="200"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="241"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="302"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="353"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="392"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="456"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="481"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="529" mass="57624" checksum="40E240FEF044EFAC" modified="2010-01-19" version="1">MAISLGNAFIKNFLGKAPDWYKVAIIAFLIINPIVFFLVDPFVAGWLLVVEFIFTLAMALKCYPLQPGGLLAIEAVAIGMTSPEQVKHELVANIEVLLLLVFMVAGIYFMKQLLLFIFTKILIGIRSKVLLSLAFCVMAAFLSAFLDALTVIAVVISVTVGFYSIYHKVASEQDPNSQHDHTSDENVQEVSRDDLENYRAFLRSLLMHAGIGTALGGVTTMVGEPQNLIIADQAGWQFGEFIIRMAPVTVPVFICGLLTCILVEKFHLFGYGARLPENVRKILVDFDNEERKSRTNLDYAKLIIQVVIAVWLIVGLALHLAAVGLIGLTVIILATSFTGITEEHALGKAFEEALPFTALLAVFFSIVAVIIDQHLFAPIIQWVLSMEGSAQLTMFYVANGILSMVSDNVFVGTVYINEVKAALLDGVITRDQFDMLAVAINTGTNLPSVATPNGQAAFLFALTSAIAPLIRLSYGRMVYMALPYTIVLTLVGLAGIELLLVPMTHWFEATGWLTAPAAEAIQAVVPAAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVR6</accession>
    <name>D0YVR6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Magnesium transporter putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_002007</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299159.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002007"/>
    <dbReference type="EnsemblBacteria" id="EEZ40975">
        <property type="protein sequence ID" value="EEZ40975"/>
        <property type="gene ID" value="VDA_002007"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0598">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="822653at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046873">
        <property type="term" value="F:metal ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045861">
        <property type="entry name" value="CorA_cytoplasmic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045863">
        <property type="entry name" value="CorA_TM1_TM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002523">
        <property type="entry name" value="MgTranspt_CorA/ZnTranspt_ZntB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01544">
        <property type="entry name" value="CorA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143865">
        <property type="entry name" value="SSF143865"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144083">
        <property type="entry name" value="SSF144083"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="261"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="295"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="321" mass="36633" checksum="1F4AFFA858EACB6C" modified="2010-01-19" version="1">MANCFVYSYVLNGKLKYSQLTLEQINDWDDEDGLLWLHLNYNSPDAQEWIKNSDLPDIEKDSLLASRIRPRANRSKDGLFLALRAINLNDSPKEDDMTSVRGYFTKHLIVTTSNHDIDSLQSIANHIRDGFGPKNTGSFIVSLCDHLASHKMNLIDVLDDQVTDLEDRILAKADPDLRSDVAVIRRQTVYTRRYVAPQRDALAKLMTTETPLLSLTDRQKLHEVNDKLSHVLDDLNSIRERANVTQEELMSLQSESLNQRVYFLSLVTTIFLPLGFLTGLLGVNLGGIPGAQDGRAFTIFCILLAFVFMLQLLFFYRRKWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVS0</accession>
    <name>D0YVS0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002011</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299170.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40979">
        <property type="protein sequence ID" value="EEZ40979"/>
        <property type="gene ID" value="VDA_002011"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4102">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="663130at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010869">
        <property type="entry name" value="DUF1501"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07394">
        <property type="entry name" value="DUF1501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="436" mass="47925" checksum="98CB323F6A8E354B" modified="2010-01-19" version="1">MKISRRRFLQSAAAVSATSASVLPNIALASSSISDYKALVVVFLYGGNDAYNMIVPTSPDAYQSYLSARPALGLTQSEILPLSLHSENQISLGIHSAMSDLLPLFESGQASVLLNTGQLLTPATRSTIAAGLSPLPEFLMAHNMQQDMWQTGATNYNNSLGWAGRMMDMLANNTSISPLISLNSQRRFNSAKNLSQTVISSQGVGQYSSWHDSVRLDEYFAHFKADYDNVYTQHFANTMKKSVSENTELKNVLDAHPSSIVYPDSKLATQLQMVARMISARQSLGHQRQVFFVGIGGFDTHFNQKPTHHALLQQLAQALALFQQDLEQQGVTQNVTTVTMSDFGRRVMANESGTDHGWAGHQLILGGAIKGQKAYGTWPDLTPGSENDYNNGRMIPTIAADQVHATLCRWFGLSDQQILELFPNLINFRSPYIDCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVW2</accession>
    <name>D0YVW2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002043</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299257.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002043"/>
    <dbReference type="EnsemblBacteria" id="EEZ41011">
        <property type="protein sequence ID" value="EEZ41011"/>
        <property type="gene ID" value="VDA_002043"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031VUZ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1589240at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="192" mass="21599" checksum="9B752AEAAAF3A195" modified="2010-01-19" version="1">MKIETLLSKFDIKGINYGPSTGGGNPLLSAEEQLAVVGLCWHESPVGWLLLFVEGLRDVNALKQLQIATMGEALRLMEDWRGVYPEKAIKALCATAIAEATQQQGQICPECNGSAVVLSKCNHKRKCQCCKDGRIEWTQETRFAYFARTLPVTYNRFKRYLVVLNVLVEWLIDSRIIAVFSMKNKIAIEKSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW08</accession>
    <name>D0YW08_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5 6">50S ribosomal protein L19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplS</name>
        <name evidence="7" type="ORF">VDA_001313</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the bacterial ribosomal protein bL19 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297849.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001313"/>
    <dbReference type="EnsemblBacteria" id="EEZ40288">
        <property type="protein sequence ID" value="EEZ40288"/>
        <property type="gene ID" value="VDA_001313"/>
    </dbReference>
    <dbReference type="GeneID" id="57339795"/>
    <dbReference type="eggNOG" id="COG0335">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1698718at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00402">
        <property type="entry name" value="Ribosomal_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038657">
        <property type="entry name" value="L19_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001857">
        <property type="entry name" value="Ribosomal_L19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018257">
        <property type="entry name" value="Ribosomal_L19_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15680">
        <property type="entry name" value="PTHR15680"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01245">
        <property type="entry name" value="Ribosomal_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002191">
        <property type="entry name" value="Ribosomal_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00061">
        <property type="entry name" value="RIBOSOMALL19"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01024">
        <property type="entry name" value="rplS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01015">
        <property type="entry name" value="RIBOSOMAL_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 7" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="116" mass="13072" checksum="982B7F2F1547CEDE" modified="2010-01-19" version="1">MSNIIKALEQEQMKQDLPAFAPGDTVVVQVKVKEGDRERLQAFEGVVIAKRNRGLHSAFTVRKISNGEGVERAFQTHSPVVNSITVKRRGAVRRAKLYYLRDRSGKAARIREKLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW14</accession>
    <name>D0YW14_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">T-protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001319</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-tyrosine biosynthesis; (4-hydroxyphenyl)pyruvate from prephenate (NAD(+) route): step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Metabolic intermediate biosynthesis; prephenate biosynthesis; prephenate from chorismate: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297855.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001319"/>
    <dbReference type="EnsemblBacteria" id="EEZ40294">
        <property type="protein sequence ID" value="EEZ40294"/>
        <property type="gene ID" value="VDA_001319"/>
    </dbReference>
    <dbReference type="GeneID" id="57339788"/>
    <dbReference type="eggNOG" id="COG0287">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1605">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="533829at2"/>
    <dbReference type="UniPathway" id="UPA00120">
        <property type="reaction ID" value="UER00203"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00122">
        <property type="reaction ID" value="UER00961"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004106">
        <property type="term" value="F:chorismate mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008977">
        <property type="term" value="F:prephenate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004665">
        <property type="term" value="F:prephenate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046417">
        <property type="term" value="P:chorismate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006571">
        <property type="term" value="P:tyrosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.59.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008244">
        <property type="entry name" value="Chor_mut/prephenate_DH_T"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036263">
        <property type="entry name" value="Chorismate_II_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036979">
        <property type="entry name" value="CM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002701">
        <property type="entry name" value="CM_II_prokaryot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011277">
        <property type="entry name" value="CM_T"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003099">
        <property type="entry name" value="Prephen_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01817">
        <property type="entry name" value="CM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02153">
        <property type="entry name" value="PDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001499">
        <property type="entry name" value="Chor_mut_pdh_Tpr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00830">
        <property type="entry name" value="CM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48600">
        <property type="entry name" value="SSF48600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01799">
        <property type="entry name" value="CM_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51168">
        <property type="entry name" value="CHORISMATE_MUT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51176">
        <property type="entry name" value="PDH_ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="1 2 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0827">Tyrosine biosynthesis</keyword>
    <feature type="domain" description="Chorismate mutase" evidence="3">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="Prephenate/arogenate dehydrogenase" evidence="4">
        <location>
            <begin position="99"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR001499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="376" mass="42145" checksum="984F8BD68D099CA5" modified="2010-01-19" version="1">MVAELSKLRDQIDEVDQQMVALLARRLALVEEVGHVKSQHGLPIYAPDREAAMLASRRAEAESQGVPPDLIEDILRRTMRESYSSENDSGFKCLKPTLRPIVVVGGYGQLGGLFCRLFELSGYQVRKLGSQDWDRADELLSDAGMVVVTVPINLTVDVISKLNALPDDCILADLTSIKSEPLQAMLEVHSGPVLGLHPMFGPDISSLAKQVIVYCDGRNPEEYQWLLEQFQIWGASLNRISAIEHDQGMTLIQALRHFTSFVYGVHLAEEDPNLDQLLSLSSPIYRLELAMVGRLFAQDAELYADIIMSSPQNLAMIQRFHQRFGEAIAMLENKDKAMFTQAFTQVDNWFGDYAEHFLLESQGLLRQANDSTHRKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW62</accession>
    <name>D0YW62_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AMP nucleosidase</fullName>
            <ecNumber evidence="2">3.2.2.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">AMP nucleosidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_001347</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>AMP + H2O = adenine + D-ribose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:20129"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="3.2.2.4"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="3.2.2.4" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297895.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001347"/>
    <dbReference type="EnsemblBacteria" id="EEZ40322">
        <property type="protein sequence ID" value="EEZ40322"/>
        <property type="gene ID" value="VDA_001347"/>
    </dbReference>
    <dbReference type="GeneID" id="57339750"/>
    <dbReference type="eggNOG" id="COG1611">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="424615at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008714">
        <property type="term" value="F:AMP nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1850.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021826">
        <property type="entry name" value="DUF3412"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031100">
        <property type="entry name" value="LOG_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037153">
        <property type="entry name" value="YgdH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027820">
        <property type="entry name" value="YgdH_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11892">
        <property type="entry name" value="DUF3412"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14793">
        <property type="entry name" value="DUF4478"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03641">
        <property type="entry name" value="Lysine_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4478" evidence="5">
        <location>
            <begin position="4"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3412" evidence="4">
        <location>
            <begin position="330"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00031983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF11892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF14793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="458" mass="51254" checksum="7A7F85D2FE87E150" modified="2010-01-19" version="1">MITHISPVGTMALLSQLEVDRLKATASSDLYRLYRNCSLAVLNSGSHTDSSKELLEQYKTFDINVQRRERGIKLELVNPPEHAFVDKKLIRGIQEHMFSVLRDIVYVNMHLELHKELNLTSSTHITNFVFSILRNAKALHAGEDPNIVVCWGGHSINPIEYQYTREVGNELGLRELNVCTGCGPGAMEGPMKGAAIGHAKQRYPSSRFIGLTEPSIIAAEPPNPIVNELVIMPDIEKRLEAFIRLGDGIVIFPGGAGTAEEFLYILGILMDPSNADQPMPVVLTGPKESEEYFRTLDSFIRDTLGEAATKHYQIIIDDPAAVAKVMKKAMPKIKAHRQEKEDAYCFNWSLNIPSDFQHPFEPTHEAMASLDLHTNQKPEQLAANLRRAFSGIVAGNVKEEGIQAIEKYGKFQINGEASLMKRMDKLLQSFVDQQRMKLPGSKYEPCYEIITESEPTAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWC8</accession>
    <name>D0YWC8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Ribonuclease HII</fullName>
            <shortName evidence="11">RNase HII</shortName>
            <ecNumber evidence="11">3.1.26.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">rnhB</name>
        <name evidence="14" type="ORF">VDA_001372</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 11 12">Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11 12">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="11">Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 11 12">Belongs to the RNase HII family.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.4" evidence="11"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297944.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001372"/>
    <dbReference type="EnsemblBacteria" id="EEZ40347">
        <property type="protein sequence ID" value="EEZ40347"/>
        <property type="gene ID" value="VDA_001372"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0164">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1685277at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004523">
        <property type="term" value="F:RNA-DNA hybrid ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07182">
        <property type="entry name" value="RNase_HII_bacteria_HII_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00052_B">
        <property type="entry name" value="RNase_HII_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022898">
        <property type="entry name" value="RNase_HII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001352">
        <property type="entry name" value="RNase_HII/HIII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024567">
        <property type="entry name" value="RNase_HII/HIII_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10954">
        <property type="entry name" value="PTHR10954"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10954:SF18">
        <property type="entry name" value="PTHR10954:SF18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01351">
        <property type="entry name" value="RNase_HII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 11 12" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="9 11 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 11" id="KW-0464">Manganese</keyword>
    <keyword evidence="7 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 11 12" id="KW-0540">Nuclease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase_HII" evidence="13">
        <location>
            <begin position="17"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="20"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="21"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEZ40347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="201" mass="22001" checksum="61D069527D83F948" modified="2010-01-19" version="1">MTKELEPFVYPEANLIAGVDEVGRGPLVGAVVTAAVILDPNNPIEGLTDSKKLSEKKRNALFDEIKEKALAWSLGRCEADEIDELNILQATMVAMQRAVAGLNITPDFVLIDGNKTPELPMAAQAVVKGDLRVAEISAASILAKVTRDREMDELDAQYPQFGFAKHKGYPTKAHFAALEEHGVIEQHRKSFKPVKRILGLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWF4</accession>
    <name>D0YWF4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted glutamine amidotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001402</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298005.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001402"/>
    <dbReference type="EnsemblBacteria" id="EEZ40377">
        <property type="protein sequence ID" value="EEZ40377"/>
        <property type="gene ID" value="VDA_001402"/>
    </dbReference>
    <dbReference type="GeneID" id="57339677"/>
    <dbReference type="eggNOG" id="COG0121">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="693464at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026869">
        <property type="entry name" value="EgtC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13230">
        <property type="entry name" value="GATase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="1">
        <location>
            <begin position="2"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="259" mass="29290" checksum="F1A79A9FDB771863" modified="2010-01-19" version="1">MCELLGMSANVPTDICFSFTGLMQRGGNTGPHRDGWGITFYEGKGFRTFKDPNPSCQSRIAELVQEYPIKSCAVISHIRQANRGGVNLENTHPFTRELWGRYWTFAHNGQLTGYDALDTGRFQAVGDTDSEIAFCWLLNQVEAKYPKPPQDMAEAFAFIHQCCERLRQLGVYNMLLSDGEYVLTFCTNNLHSITRRAPFGCASLIDEDVTIDFQQETTPNDVVTVIATQPLTNNEQWHKMQPGEFNVFYFGEVVYQAQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWH1</accession>
    <name>D0YWH1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Leucine--tRNA ligase</fullName>
            <ecNumber evidence="9">6.1.1.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Leucyl-tRNA synthetase</fullName>
            <shortName evidence="9">LeuRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">leuS</name>
        <name evidence="14" type="ORF">VDA_001430</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + L-leucine + tRNA(Leu) = AMP + diphosphate + L-leucyl-tRNA(Leu)</text>
            <dbReference type="Rhea" id="RHEA:11688"/>
            <dbReference type="Rhea" id="RHEA-COMP:9613"/>
            <dbReference type="Rhea" id="RHEA-COMP:9622"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57427"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78494"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.4"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 10">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.4" evidence="9"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298048.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001430"/>
    <dbReference type="EnsemblBacteria" id="EEZ40404">
        <property type="protein sequence ID" value="EEZ40404"/>
        <property type="gene ID" value="VDA_001430"/>
    </dbReference>
    <dbReference type="GeneID" id="57339645"/>
    <dbReference type="eggNOG" id="COG0495">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="32262at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004823">
        <property type="term" value="F:leucine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006429">
        <property type="term" value="P:leucyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00049_B">
        <property type="entry name" value="Leu_tRNA_synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002302">
        <property type="entry name" value="Leu-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025709">
        <property type="entry name" value="Leu_tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43740">
        <property type="entry name" value="PTHR43740"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13603">
        <property type="entry name" value="tRNA-synt_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00985">
        <property type="entry name" value="TRNASYNTHLEU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="SSF50677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00396">
        <property type="entry name" value="leuS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-synt_1" evidence="11">
        <location>
            <begin position="14"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA-synt_1_2" evidence="13">
        <location>
            <begin position="221"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA-synt_1" evidence="11">
        <location>
            <begin position="417"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA-synt_1" evidence="11">
        <location>
            <begin position="618"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="domain" description="Anticodon_1" evidence="12">
        <location>
            <begin position="700"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="9">
        <location>
            <begin position="42"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="9">
        <location>
            <begin position="618"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="621"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF13603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEZ40404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="858" mass="97105" checksum="684B1BBF881FB954" modified="2010-01-19" version="1">MQEQYRPQDIEQKVQEHWDNNKTFVVSEDPNKEKFYCLSMFPYPSGRLHMGHVRNYTIGDVISRYQRLQGKNVMQPIGWDAFGLPAENAAVKNKTAPAPWTYENIEYMKNQLKLLGFGYDWNREFATCTPEYYRWEQEFFTKLYEKGLVYKKTSSVNWCPNDQTVLANEQVEDGCCWRCDTPVEQKEIPQWFIKITEYAEELLNDLDQLDGWPDMVKTMQRNWIGRSEGVELEFNVVGQDKPLEVYTTRPDTLMGVTFVSIAAGHPLAAQAAENNPALADFIHECRNNKVAEADLATMEKKGMDTGLTAIHPLDGREVPVYVANFVLMDYGTGAVMAVPAHDQRDFEFATKYGIDIMAVIKPEDGSELDISEAAYTEKGILFNSGEFDGLDFQGAFDAIAAKLEAENKGKKTVNYRLRDWGVSRQRYWGAPIPMLTTEDGEVHPVPADQLPVILPEDVVMDGVTSPIKADKEWAKTTFNGEPALRETDTFDTFMESSWYYARYCSPQADDILDPEKANYWLPVDQYIGGIEHACMHLLYSRFFHKLLRDAGYVTSDEPFKQLLCQGMVLADAFFYTNEKGGKEWVAPTEVTVERDGKGRITKAVNTEGREVEHSGMIKMSKSKNNGIDPQEMVEKYGADTVRLFMMFASPADMTLEWQESGVEGANRFLKRVWKLVHELTADGAIEALDVAALTGDQKALRRDVHKTIAKVSDDIGRRQTFNTAIAAIMELMNKLTKASLESAQDRALMDEALKAIVRMLYPITPHVCFTMWEALGESDIDHAVWPQADEKALVEDEKLIIVQVNGKLRAKLTVAADATKEQVEDLGLNDENVTKFTDGLTVRKVIYVPGKLLNIVAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWJ5</accession>
    <name>D0YWJ5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Endonuclease I</fullName>
            <ecNumber evidence="3">3.1.21.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001237</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the EndA/NucM nuclease family.</text>
    </comment>
    <dbReference type="EC" id="3.1.21.1" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297700.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001237"/>
    <dbReference type="EnsemblBacteria" id="EEZ40215">
        <property type="protein sequence ID" value="EEZ40215"/>
        <property type="gene ID" value="VDA_001237"/>
    </dbReference>
    <dbReference type="GeneID" id="57339885"/>
    <dbReference type="eggNOG" id="COG2356">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1114630at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004530">
        <property type="term" value="F:deoxyribonuclease I activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007346">
        <property type="entry name" value="Endonuclease-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044925">
        <property type="entry name" value="His-Me_finger_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33607">
        <property type="entry name" value="PTHR33607"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04231">
        <property type="entry name" value="Endonuclease_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54060">
        <property type="entry name" value="SSF54060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019850" evidence="2">
        <location>
            <begin position="21"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="234" mass="27154" checksum="30A008C9CA728E09" modified="2010-01-19" version="1">MRPSLRLLVLGALLPLTAFAKAPANFSSAKRVASELYQEHPITFYCGCDIKWQGKKMVPDLESCGYQVRKQEKRANRIEWEHVVPAWQFGHQLQCWQNGGRKECGKDKTFKKMESDLHNLTPAIGEVNGDRSNFQFMPWNGNEGAYYGQCEMKIDFKGRRADPPTRARGAIARTYLYMNNKYKFNLSKQQRRLMEAWDKMYPVTAWECQRDREIAKIQGNHNPFVHNACQTAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWL5</accession>
    <name>D0YWL5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hypothetical lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001506</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298177.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001506"/>
    <dbReference type="EnsemblBacteria" id="EEZ40480">
        <property type="protein sequence ID" value="EEZ40480"/>
        <property type="gene ID" value="VDA_001506"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502ZAMG">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1053390at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.360.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021308">
        <property type="entry name" value="GfcB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023373">
        <property type="entry name" value="YmcC_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11102">
        <property type="entry name" value="YjbF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159270">
        <property type="entry name" value="SSF159270"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019853" evidence="1">
        <location>
            <begin position="22"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="233" mass="25992" checksum="4526431FBA9D5359" modified="2010-01-19" version="1">MNVNKLVLPVALLLLSGCSQRANDANDTVKLAMFGTPDVVKTAQEIKQLPYASTYVRIGDHSQIFMVLALAETKYLPASRQLTTNIANPLQLKWMSSDNGMLVTENGRIVKTLNLQDGNLLSSDSKQTDPLLLGLQKSTTPLTWQRTISWQPGYHMGYHLSSTFHNDGIQLVDINGQQVKALQFSETVKVKELDRSYQNTFWLDPINGKVIKSQQYPAPSMPLITMTILKPFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWM1</accession>
    <name>D0YWM1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">O-antigen flippase Wzx</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001512</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298189.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001512"/>
    <dbReference type="EnsemblBacteria" id="EEZ40486">
        <property type="protein sequence ID" value="EEZ40486"/>
        <property type="gene ID" value="VDA_001512"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2244">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="564091at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="222"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="251"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="292"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="328"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="387"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="426"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="452"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="487" mass="56485" checksum="446FD869D52A1C41" modified="2010-01-19" version="1">MGNFRNSVLFSIIFTLITGILAFFINKVFSDSLGQENLGILRLFTQLLAYLNLAELGVGAAASATLYRYLNENNIIKINGVLLTVRYFYRRIGFGILILGLLFNFLLPYIINDISIEIFVVWSLYVVGISITYFYSDYPIILTSDQRYQTVLIIRNLIKTTVQILQIYTLIVFESFYLFVAIFVLFNLLEWITFKVIYNNIYGDKYEKGGEKDYSVIEKTKYLFIHNLAGVLIFNTDFIIITKFIGLKIVAIYSSYLMITKFIELIFNSIVNVIRPKIGKIVASCDENKILFYFNGLLVVNIYIAAIIAFVTYYTIGFIVQLWMGNEYILQSSTLLLMSVNLFINIFRRTIDIFKEVSGYYNDIHLPVMEGFINLILSLLLVKHYGINGVIFSTVFTNIIFIIIMKPWVFYSKVLKVKFNLYLKSILKYLIVLSFILFVINFSFLSDFSLNYISLFSNSILMMLLITVVFLSVRDFRVLIKDLFKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWN2</accession>
    <name>D0YWN2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative PTS system nitrogen regulatory IIA component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_001488</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298145.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001488"/>
    <dbReference type="EnsemblBacteria" id="EEZ40462">
        <property type="protein sequence ID" value="EEZ40462"/>
        <property type="gene ID" value="VDA_001488"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1762">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1794214at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000032">
        <property type="entry name" value="HPr-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035895">
        <property type="entry name" value="HPr-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016152">
        <property type="entry name" value="PTrfase/Anion_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002178">
        <property type="entry name" value="PTS_EIIA_type-2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016910">
        <property type="entry name" value="UCP029195_PTS_EIIA2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00359">
        <property type="entry name" value="PTS_EIIA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029195">
        <property type="entry name" value="UCP029195_PTS_EIIA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55594">
        <property type="entry name" value="SSF55594"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55804">
        <property type="entry name" value="SSF55804"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51094">
        <property type="entry name" value="PTS_EIIA_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51350">
        <property type="entry name" value="PTS_HPR_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0598">Phosphotransferase system</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="HPr" evidence="6">
        <location>
            <begin position="2"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="PTS EIIA type-2" evidence="5">
        <location>
            <begin position="118"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="268" mass="30351" checksum="EB12C43AE91FFB77" modified="2010-01-19" version="1">MAISQHILFYCGEGGLPLYQLNRLKKLADYFRSSMSLVNVTLHKSANIDQPLRVLALATKPQDLCLFHIEGLDAELAHRVVLNFLAEYQHPFFAKQRTTEQALDIVEDKRQQYCDWLHFDDNQMIKANFNTHPPTKTAVLDTLAQTIALDNRQMGPQAITQAFQNREQISATVMNHYIALPHIMNEQVEQPSLAVYLSNLPIDWHSPRGPVSLIIALALPKPATREMIMPFAQFSKSLLESTYCQGLLSVTDTAEFRAIIVEGMSTRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWN9</accession>
    <name>D0YWN9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mutator family transposase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_001525</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">Required for the transposition of the insertion element.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the transposase mutator family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298217.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001525"/>
    <dbReference type="EnsemblBacteria" id="EEZ40499">
        <property type="protein sequence ID" value="EEZ40499"/>
        <property type="gene ID" value="VDA_001525"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3328">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="792870at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001207">
        <property type="entry name" value="Transposase_mutator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33217">
        <property type="entry name" value="PTHR33217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00872">
        <property type="entry name" value="Transposase_mut"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01007">
        <property type="entry name" value="TRANSPOSASE_MUTATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0814">Transposable element</keyword>
    <keyword evidence="4 6" id="KW-0815">Transposition</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="402" mass="46586" checksum="80487B4EE10D0FE4" modified="2010-01-19" version="1">MDKKALEAFAREAAKSIKTESDLDDFRKMLTKVTVETALNAELDEHLGYQKHQARTNSNSRNGYSGKSIIADDGEVDIEIPRDREASFEPQLIRKHQTRFQSMDDKILSLYAKGMTTREIVATFKEMYDADVSPTLISKVTDSVLEQVIEWQSRPLDEVYPIVYLDCIVIKVRQDKQVINKAVYLALGVNMEGQKELLGMWLSETEGAKFWLNVLTELQNRGVKDILIACVDGLKGFPDAINTVFPETQIQLCIVHMVRNSVKYVPWKDYRAVTVDLKKIYQSATEDEALLALEQFSARWDSKYPQISRSWTTHWDNLNTLFNYPEDIRRAIYTTNAIESLNSVIRKAIKKRKLFPTDESARKVIYLAIRDASKKWTMPIRNWRQALNRFIIMFEDRLSEYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWX8</accession>
    <name>D0YWX8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Hypothetical peptide ABC transporter peptide-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001811</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial solute-binding protein 5 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298748.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001811"/>
    <dbReference type="EnsemblBacteria" id="EEZ40779">
        <property type="protein sequence ID" value="EEZ40779"/>
        <property type="gene ID" value="VDA_001811"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4166">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="162819at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030678">
        <property type="entry name" value="Peptide/Ni-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023765">
        <property type="entry name" value="SBP_5_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002741">
        <property type="entry name" value="MppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01040">
        <property type="entry name" value="SBP_BACTERIAL_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019782" evidence="3">
        <location>
            <begin position="22"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="domain" description="SBP_bac_5" evidence="4">
        <location>
            <begin position="79"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="539" mass="60419" checksum="AADD584230A217A5" modified="2010-01-19" version="1">MSAYTRLLLACAGLLSLFGCSEPTKENTIRDTGFIYCGQDTPTTLNPQLADGGLTVDSLGAQIFDRLLTLDPVSHHTQSELAKSWKVSDDGLVYTFTLRKNIPFQTTPWFTPSRPLNAEDVVFSFERIIDPNNPFHNVSGGRYPWFESNGFNKLIKSITVVNPNTVRFTLNRPDNAFLSNLATSYAVIYSKEYAEQLLKSGQLNKLDLKPIGTGPFYLSQYQPNDFIRLKRNDAYWRGKPAMEQVVFDISSRGTGTLAKLLSQECDVLSSPVASQLPVISNDKNFNLTAQTGMNVAFLAFNTEKKPLNNLKVREAISMAINREALLNSVYYGTATNAKSLLPPMSWAYNHDSVVPNYDPKEAKALLKQAGYNHNLTLTMWVPLEPRPYNPSPRKTAELIQANLKSVGVNLVLDYQEQVDRTSLSNINKFDLILSGWIADNGDPDNFLRPLLSCDAKEAQLNIANWCNLQFDNLLELALRTNQQSQRLNYYYLAQDILDKDLPILPLAHGVYFQANNKSLSGVQMSPFGTRSFADVHRSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWY6</accession>
    <name>D0YWY6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">HTH-type transcriptional regulatory protein TyrR</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">VDA_001819</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298766.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001819"/>
    <dbReference type="EnsemblBacteria" id="EEZ40787">
        <property type="protein sequence ID" value="EEZ40787"/>
        <property type="gene ID" value="VDA_001819"/>
    </dbReference>
    <dbReference type="GeneID" id="57342066"/>
    <dbReference type="eggNOG" id="COG3283">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="123059at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019439">
        <property type="term" value="P:aromatic compound catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030828">
        <property type="entry name" value="HTH_TypR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025944">
        <property type="entry name" value="Sigma_54_int_dom_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18024">
        <property type="entry name" value="HTH_50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00158">
        <property type="entry name" value="Sigma54_activat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04381">
        <property type="entry name" value="HTH_TypR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00688">
        <property type="entry name" value="SIGMA54_INTERACT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50045">
        <property type="entry name" value="SIGMA54_INTERACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0058">Aromatic hydrocarbons catabolism</keyword>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0678">Repressor</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="ACT" evidence="10">
        <location>
            <begin position="2"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="9">
        <location>
            <begin position="78"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="8">
        <location>
            <begin position="205"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ40787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="513" mass="58176" checksum="F1DB6C25DBC1824D" modified="2010-01-19" version="1">MRLQVFCEDRVGITRELLDILTAQQIDLRGIEIDRIGIIYLNCPEVAFESFSQLMSQIRQLDGVTDVRRIQFMPSEREHKELSALLQTLPDPFFSINLQGKVDLSNHAAEVLMGKEQQVMLGESIHHLLGFNFHQWLEKEQAKRRSEMVVISGIDYVMDIMPVYVADDNEDEVLASAVILLKSLSEAKMPIAMRKISGNQGFEHLIGHSSRFKHLVAQAKKLALLDAPLLIQGETGTGKEMLARACHQRSLRRDKPFMVVNCVSMPDNAAETELFGEVATIGEPSKKGIFEQAEGGTVFLYEIGEMSPHLQVKLLRFLQDGTFRRVGEEKEIKVNVRVICSTQKRLHELVAAGQFREDLYYRLNVLALVVPPLRERVADILPLSELFLSQFAKELQQTKPSISDEVSHCLTQYAWPGNIRQLRNILFRAMTQVESDVLQMEDIHLPENEVSSSIISDETLEGSLDEIMKRYESGILANLYKTYPSTRKLATRLGVSHTAIANKLREYDLTKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX30</accession>
    <name>D0YX30_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HlyD_D23 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001904</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298907.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001904"/>
    <dbReference type="EnsemblBacteria" id="EEZ40872">
        <property type="protein sequence ID" value="EEZ40872"/>
        <property type="gene ID" value="VDA_001904"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0845">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1200399at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HlyD_D23" evidence="2">
        <location>
            <begin position="56"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="363" mass="40457" checksum="5233D44B3BCA0638" modified="2010-01-19" version="1">MYYRLYIHLWLVCSVMLQNVAFASELKSPLLINGLQLEPQTSYQIPREFVGFIQAKQQTSLGSELNGKVKRILVDVGRNVTAGTPLLELDTDLLQTEKQQLFAQQQQFQAQLDLINTNLARQQTLQAKGFSAASEIDSLQSQRKALLANLSQLHATLAANQLKLTKSTIRAPYNGKISERFVSQGDVINIGTPTFTLLANDLTEAHIGVPAKYMTQILNQPSWQIRINNKLYPAQLLNPGASIDLNSRTVELRFALQAPLLTGELAYLTYQDHQQQNGYWIPLTALTEGLRGVWTVMAIVPKSDKNHQILERRTVKVIFANGTDAYITGAIHPHEQIVADGLHRVVAGQEVETALQPKGKNNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXE4</accession>
    <name>D0YXE4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="13 14 15">UvrABC system protein B</fullName>
            <shortName evidence="14">Protein UvrB</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Excinuclease ABC subunit B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">uvrB</name>
        <name evidence="19" type="ORF">VDA_001623</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11 14">The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12 14 15">Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14 15">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="14">The beta-hairpin motif is involved in DNA binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 14 15">Belongs to the UvrB family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298393.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001623"/>
    <dbReference type="EnsemblBacteria" id="EEZ40596">
        <property type="protein sequence ID" value="EEZ40596"/>
        <property type="gene ID" value="VDA_001623"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0556">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="95696at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009380">
        <property type="term" value="C:excinuclease repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009381">
        <property type="term" value="F:excinuclease ABC activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00204">
        <property type="entry name" value="UvrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001943">
        <property type="entry name" value="UVR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036876">
        <property type="entry name" value="UVR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004807">
        <property type="entry name" value="UvrB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041471">
        <property type="entry name" value="UvrB_inter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024759">
        <property type="entry name" value="UvrB_YAD/RRR_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24029">
        <property type="entry name" value="PTHR24029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12344">
        <property type="entry name" value="UvrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17757">
        <property type="entry name" value="UvrB_inter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46600">
        <property type="entry name" value="SSF46600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00631">
        <property type="entry name" value="uvrb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 14" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 14 15" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 14 15" id="KW-0228">DNA excision</keyword>
    <keyword evidence="9 14 15" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8 14 15" id="KW-0267">Excision nuclease</keyword>
    <keyword evidence="4 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 14 15" id="KW-0742">SOS response</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="17">
        <location>
            <begin position="26"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="18">
        <location>
            <begin position="432"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="domain" description="UVR" evidence="16">
        <location>
            <begin position="635"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Beta-hairpin" evidence="14">
        <location>
            <begin position="92"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="39"/>
            <end position="46"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00025647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00026033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00029504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU003587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EEZ40596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="675" mass="76702" checksum="E83B9ED51765256A" modified="2010-01-19" version="1">MNDVFSIASEFSPSGDQPTAIKQLLEGLDAGLAHQTLLGVTGSGKTFTIANVIAEAKRPTLFLAPNKTLAAQLYGEMKEFFPNNAVEYFVSYYDYYQPEAYVPTTDTFIEKDASVNAHIEQMRLSATKALMERRDVIIIASVSAIYGLGDPDSYLKMMLHVRRGDMLDQRDILRRLAELQYTRNDMAFERGTFRVRGEVIDIFPAESEKEAVRIELFDDEVDRISLFDPLTGSVIQQDLPRYTVYPKTHYVTPREKILEAIEGIKVELESRRKQFMDGNKLVEEQRITQRTQFDVEMMNELGFCSGIENYSRYLSGRSEGEPPPTLFDYLPADGLLIIDESHVTVSQIGAMFRGDRSRKENLVEYGFRLPSALDNRPLKFEEFESLAPQTIYVSATPGKYEIEKSDGEIAEQVVRPTGLLDPEIEVRPVATQVDDLLSEIRIRAAKDERVLVTTLTKRMAEDLTEYLAEHGVRVRYLHSDIDTVERVEIIRDLRLGEFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNLEGKAILYGDKITGSMERAITETERRRDKQKLYNEQHGITPQKLNKKVADILELGSSSPKAKAHNRAAQLHKVAEKKGTYSAMSPQQLEGEIQQLEKQMYDFAQNLEFEKAAELRDKIHTLREQFITNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXK5</accession>
    <name>D0YXK5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA helicase</fullName>
            <ecNumber evidence="3">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_001719</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the helicase family. UvrD subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001719"/>
    <dbReference type="EnsemblBacteria" id="EEZ40690">
        <property type="protein sequence ID" value="EEZ40690"/>
        <property type="gene ID" value="VDA_001719"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0210">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013986">
        <property type="entry name" value="DExx_box_DNA_helicase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014017">
        <property type="entry name" value="DNA_helicase_UvrD-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000212">
        <property type="entry name" value="DNA_helicase_UvrD/REP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022161">
        <property type="entry name" value="Helicase_IV_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014016">
        <property type="entry name" value="UvrD-like_ATP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11070">
        <property type="entry name" value="PTHR11070"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12462">
        <property type="entry name" value="Helicase_IV_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00580">
        <property type="entry name" value="UvrD-helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13361">
        <property type="entry name" value="UvrD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51198">
        <property type="entry name" value="UVRD_HELICASE_ATP_BIND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 8" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UvrD-like helicase ATP-binding" evidence="7">
        <location>
            <begin position="201"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="222"/>
            <end position="229"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ40690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="701" mass="80907" checksum="703CAD02F9D6159E" modified="2010-01-19" version="1">MEIGETMQLSASRLAQWLVQGDYYSIELQDNRLVLESQTETDEISFDDWDGSIDVHRGVMWGTLELTSSDQKYCWTVHGLPWRECKPFAQDLVQTYQNWAHARVAKLDAALPEMLKRIHAFTGQKGYLRDSEHDDLYQLLTSSLEHSELTPELAASFRPKAFEHILPWLGDNDVWVDEHNKKWIEKESNKWGSWFDSFESSPLNPSQREAVLINQDHNLVLAGAGSGKTSVLVARAGYLIASQKALPEEILMLAFGRMASEEMNARMRTKVSDRVKVATFHSLGTEIIRQVEHERPNVSPIALDDKARSAWIARMLMEQWNKPASAKRWQRHLTQWRIPGFSKENSMEQQAENEQTINWIWRHIELLGQRGATKEQLLNDIQDSSNPAMRPRMKSELELLWPCYEAYQQHLKVKKQIDFNSMIKVATQYVKEGKFISPWRFVMVDEYQDISPLRLSLIEALCQPQPNSDKAAPTLFAVGDDWQAIYRFAGSDVNLTTDFEERFGATHITQLSTTYRFNNMIGDVANVFVQQNPMQVKKELTSFKKQKKKAVTLLAQDFILQELGQLAKRYEGKQTNVLILGRNNKQRPAKLEAWQEQWPQLNLQYMTCHASKGQEAQYVFIVDVNKGIFPTLDRETGLASILQSRAETYADAEERRLFYVALTRAKKHVYVCANPMNVSPFINELIEDKYPVDNKIKRIGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXR1</accession>
    <name>D0YXR1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ribosomal RNA small subunit methyltransferase F</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_002074</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002074"/>
    <dbReference type="EnsemblBacteria" id="EEZ41042">
        <property type="protein sequence ID" value="EEZ41042"/>
        <property type="gene ID" value="VDA_002074"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0144">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3270">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001510">
        <property type="term" value="P:RNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001678">
        <property type="entry name" value="MeTrfase_RsmB/NOP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027391">
        <property type="entry name" value="Nol1_Nop2_Fmu_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011023">
        <property type="entry name" value="Nop2p"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023267">
        <property type="entry name" value="RCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22807">
        <property type="entry name" value="PTHR22807"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01189">
        <property type="entry name" value="Methyltr_RsmB-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13636">
        <property type="entry name" value="Methyltranf_PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02008">
        <property type="entry name" value="RCMTFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00446">
        <property type="entry name" value="nop2p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51686">
        <property type="entry name" value="SAM_MT_RSMB_NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SAM_MT_RSMB_NOP" evidence="5">
        <location>
            <begin position="1"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="4">
        <location>
            <begin position="21"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="143"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="373" mass="41857" checksum="D244F456EFF99FA3" modified="2010-01-19" version="1">MMPVTALLKDNDNLDVVLDMASAPGSKTTQIACAMENRGALVANELAASRIKVLHSNLQRCGVYSVALTHFDGCVFGGWAPESFDSILLDAPCSGEGAIRKDEDAMKNWTLNSIEEIAEVQRNLIVSAFQALKPGGVMVYSTCTLNTRENQDVCHYLKETYGDAVEFEPLDDLFEGAKETLTEDGFLHVYPQVYDSEGFFVARIRKLAAVESPVVKKRMGKFPFSKMSNKDQAELAKQFKQDLDITLPEQNDVWVRDKEVWLFPSALSNLIGEIRFQRIGIRLAEQHKKGYRWQHEAVMTLATGKEQTAIALTAEEAKEWFMGRDIRPDQPAGKGEVIVTYRDYPIGLGKWVSNRIKNGLPRELVRDTNLFDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXY2</accession>
    <name>D0YXY2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type VI secretion-related protein VasL</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002145</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002145"/>
    <dbReference type="EnsemblBacteria" id="EEZ41113">
        <property type="protein sequence ID" value="EEZ41113"/>
        <property type="gene ID" value="VDA_002145"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010657">
        <property type="entry name" value="ImpA_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06812">
        <property type="entry name" value="ImpA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ImpA_N" evidence="1">
        <location>
            <begin position="34"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="489" mass="55379" checksum="5DA29414073CD5B5" modified="2010-01-19" version="1">MGGLELPFINGYVIVTQLYFSELQQYKLVAHEDELRDSDCYQKIRDAINKRNSPLSGSVDWQLVQQLCDELGRTDGFDFIATIYFTIAAIKNEGLAGLANGLELQVVAVDTFIRNSSFPAQKRAELYQWMLGRIGNELRALKPTQSQLRDLYRCERACQRLNEIFMEVQPEHIPDLEAIGYVVFEHIDRLENGLSLKDHGRYEDVTNQKTKYQITGNDNQVSKTSSSVVVKPNYAQHAAQSPNKESTTHTSSRSYMSFALGLILGAGGIVTGAQLFPQWFQLLSTTHSQTVSENRSLLAQSVTTSQSSGRILTLEQGKAFQTHFTAQQFAEDKSIIVPMYLQQANALITQPAGGNLIEAFSLIDIIQRLYPNDESVEQAQNRYHQIETQYDELFATQYRRFNTARSRIANLQQSINANNRANTLRLSQGINEYAIGLSPVYGRISYITEQLKQGDKNQAQIEWQNLNQELQAISFKVEQLHQDLLRSSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXY5</accession>
    <name>D0YXY5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002148</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299542.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002148"/>
    <dbReference type="EnsemblBacteria" id="EEZ41116">
        <property type="protein sequence ID" value="EEZ41116"/>
        <property type="gene ID" value="VDA_002148"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5032RR9">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1350108at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017738">
        <property type="entry name" value="T6SS-assoc_VCA0118"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11319">
        <property type="entry name" value="VasI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03360">
        <property type="entry name" value="VI_minor_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019877" evidence="1">
        <location>
            <begin position="21"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="220" mass="24281" checksum="3133F85667B9C04E" modified="2010-01-19" version="1">MIKQVLMVGLLSHVSISAIASVNSDEVMIQAQHCRSIGANLARLECFDRVFSTPIKTVPLIKNSTVMPQSWQWAIDSEKNRTTAVGFNANKGDSVTEGERYWLTAPAINKHFAKGKAPVLMLSCIENISRVELVFPEPIQESRVSVSIPGIPVVTQNWISDDTGYLLRSGRGIPAIEAMKSMLTAPQLILRSNAKDVDGLAFDTTDLRSVIEPMRKACRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXZ2</accession>
    <name>D0YXZ2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Protein ImpG/VasA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002155</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299555.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002155"/>
    <dbReference type="EnsemblBacteria" id="EEZ41123">
        <property type="protein sequence ID" value="EEZ41123"/>
        <property type="gene ID" value="VDA_002155"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3519">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="140284at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010272">
        <property type="entry name" value="T6SS_TssF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35370">
        <property type="entry name" value="PTHR35370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05947">
        <property type="entry name" value="T6SS_TssF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028304">
        <property type="entry name" value="UCP028304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03359">
        <property type="entry name" value="VI_chp_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="588" mass="66919" checksum="8CA0AE08B1651961" modified="2010-01-19" version="1">MSQDKFFRDELAFLKEQGAAFTEVHPQLSRFLQGKNTDPDVERLLEGFAFLTAKLREKVEDEFPELTHSIINMLWPNYLRPIPSLSIAQFTPIEKALSVGQKIPAQTEIDSIPVMETVCHFKTCRDVDIYPIAPIGITTNHTREASIIDLQLEVIGEQGLSDIGLQDLQFYLGGQKYSAQMLYLWLNHYLARIELVCGEHQFVIPKDHFKSVGFETGEGVLPFPKNVYEGYRILQEYLTFSDAFLFGELCNLSQFITSDMGQEFTLRFVFSKTLPADVRVREESFSLFCTPIINLFSHDADPIDLTGKRSEYRMVPSSRYPTHYEIFSIDKVQGWQEAHEGRIRGQKRVYSAFESFQHEIERSRHREALYYRARVKNSVRGDGFDHFISFVRGDETNCIGISEAISLELTCTNRQLPIELGIGDICAATNTSPSFASFKNITEPTQPLRPTLDGSLLWTLISNLSLNYLSLLSKDALCSVIRAYDFRALVDRQAERVAKLRLDGIVEINSKPIERIIKGLPVRGLQSEIMLDQVAFASEGDLYLFGSVLSRFFALYASINSFHELVVVNSANQERYTWGTQTGLQPLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY18</accession>
    <name>D0YY18_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002181</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41149">
        <property type="protein sequence ID" value="EEZ41149"/>
        <property type="gene ID" value="VDA_002181"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="58" mass="6665" checksum="F6C1A4E5792C3654" modified="2010-01-19" version="1">MLEQHAAQNDIHALSLEVNIGNGGARTFYERHDFMLRRQFCMMTKNVKTEEVPLTIAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY29</accession>
    <name>D0YY29_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NifU_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002192</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299621.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002192"/>
    <dbReference type="EnsemblBacteria" id="EEZ41160">
        <property type="protein sequence ID" value="EEZ41160"/>
        <property type="gene ID" value="VDA_002192"/>
    </dbReference>
    <dbReference type="GeneID" id="57341667"/>
    <dbReference type="eggNOG" id="COG0822">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1066272at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002871">
        <property type="entry name" value="NIF_FeS_clus_asmbl_NifU_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01592">
        <property type="entry name" value="NifU_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NifU_N" evidence="1">
        <location>
            <begin position="56"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="230" mass="24791" checksum="219B16323953ADBE" modified="2010-01-19" version="1">MQYSAEVQNMCPLSRGPQHESAPIPVEGRWVSPKDVIAISGLSHGVGTCAPQQGAAKLTLNVKNGIIEEALIETIGCSGMTHSAAMASELITGKTILEALNTDLVCDAINVAMREIFLQFVYGRTQTAFSLDGLPIGAGLEDLGKGLRSQVGTHYGTRAKGPRYMEMAEGYVTKVALDENEEIIGYRFVNLGKMMESISKGVPANEAMEQATGQYGRFDEAVRTIDPRHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY74</accession>
    <name>D0YY74_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Arginine ABC transporter periplasmic arginine-binding protein ArtI</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_002237</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the bacterial solute-binding protein 3 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299712.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002237"/>
    <dbReference type="EnsemblBacteria" id="EEZ41205">
        <property type="protein sequence ID" value="EEZ41205"/>
        <property type="gene ID" value="VDA_002237"/>
    </dbReference>
    <dbReference type="GeneID" id="57341609"/>
    <dbReference type="eggNOG" id="COG0834">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1632224at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015276">
        <property type="term" value="F:ligand-gated ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001320">
        <property type="entry name" value="Iontro_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005768">
        <property type="entry name" value="Lys_Arg_Orn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018313">
        <property type="entry name" value="SBP_3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00062">
        <property type="entry name" value="PBPb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00079">
        <property type="entry name" value="PBPe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01096">
        <property type="entry name" value="3A0103s03R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01039">
        <property type="entry name" value="SBP_BACTERIAL_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018719" evidence="6">
        <location>
            <begin position="20"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="PBPb" evidence="7">
        <location>
            <begin position="23"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="PBPe" evidence="8">
        <location>
            <begin position="23"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="245" mass="27137" checksum="763E41442C2875A6" modified="2010-01-19" version="1">MKKIVLATLIGLASTHALAAEQELKFAMEATYAPFEYIDENNQIQGFDVDLANALCQQMDVKCTFHNQAFDSLIPALKFKRYDAAISGIDITEARQQQVSFSEPYYDNAAAFVSLKDKVADQAALTGKRIGVQNGSTHQSYLLDNMSGVTAVPYSSYQDAFIDMQNGRIDAVFGDTAVVAEWFKKDPNLAYVGKPITNQKYFGNGFGIAVNKSNQELVNKLNTALKTVKANGQYQVIYDKYFSNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY78</accession>
    <name>D0YY78_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cystatin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002241</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41209">
        <property type="protein sequence ID" value="EEZ41209"/>
        <property type="gene ID" value="VDA_002241"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1574">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004869">
        <property type="term" value="F:cysteine-type endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00042">
        <property type="entry name" value="CY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000010">
        <property type="entry name" value="Cystatin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046350">
        <property type="entry name" value="Cystatin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00031">
        <property type="entry name" value="Cystatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54403">
        <property type="entry name" value="SSF54403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cystatin" evidence="2">
        <location>
            <begin position="127"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="207" mass="21931" checksum="9EF68698A3710B69" modified="2010-01-19" version="1">MACDAKDPQPKQDTQVEAQAELQQKAADLQESAKDLLNTASEKAGELGDSAKAAADDASQKVKELSDSAKVAASDMSDKTAEQVNEAADKISAAVASGADEVRKATSPECAESHHSLPGGWSKGEITPEVIDAANAAVKSLGADQKLKQVDSVSQQVVAGLNYYVKFTTEDGKEYAAKVFRSLKGEYDVKEVKLAEETEHHCGSHHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY93</accession>
    <name>D0YY93_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Isochorismatase</fullName>
            <ecNumber evidence="2">3.3.2.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002256</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.3.2.1" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299741.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002256"/>
    <dbReference type="EnsemblBacteria" id="EEZ41224">
        <property type="protein sequence ID" value="EEZ41224"/>
        <property type="gene ID" value="VDA_002256"/>
    </dbReference>
    <dbReference type="GeneID" id="57341587"/>
    <dbReference type="eggNOG" id="COG1335">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1442962at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008908">
        <property type="term" value="F:isochorismatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="SSF52499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="187" mass="21014" checksum="7C453D82C87B5995" modified="2010-01-19" version="1">MNKALIAIDFINDIVDAKGKIPSCAEQVKTHRVIDKANLAISWARNQHIPVIFVKVGFQDNYFAQPKHSPIFGKADQFGALNLSGWGTEFHCDLDVQPHDSVVIKPRVNPFYNTSLDAMLRANKIEQLYFCGVSTSWAIQSAVRDAHDRDYQVHLITDACASHSYEDHQASLAMLERLVTPHLAEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYB6</accession>
    <name>D0YYB6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Tryptophan--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_002279</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.2" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002279"/>
    <dbReference type="EnsemblBacteria" id="EEZ41247">
        <property type="protein sequence ID" value="EEZ41247"/>
        <property type="gene ID" value="VDA_002279"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0180">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="951354at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004830">
        <property type="term" value="F:tryptophan-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006436">
        <property type="term" value="P:tryptophanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00806">
        <property type="entry name" value="TrpRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002306">
        <property type="entry name" value="Trp-tRNA-ligase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01039">
        <property type="entry name" value="TRNASYNTHTRP"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00233">
        <property type="entry name" value="trpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 8 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="359" mass="39629" checksum="7427FD1D51060312" modified="2010-01-19" version="1">MRVIYSLPPVSDGNTFLLETLFMTVTSQPQKILTGDRATGQLHLGHFVGSLQQRVALQHQYQQTILIADMQGLTDNGHNPHKVASNILNVMADYLAVGIDPTKTTICLQSALPALAELTMFYSNVVSVSRLQRNPTVKAEIQSKQFGQSIPTGFLTYPISQAADITAFKATLIPVGDDQLPMIEQTNEIVRKINTIADKDILVECQPLLSHVARLPSPDGKNKMSKSMGNCIFLGASEKEIRQAVKAMFTDPNHLRIEDPGQIEGNIVFTYLDAFHPDKALVAQLKAHYQAGGLGDGQTKKVLEECLQELIKPIRERRELFMSDKAQLIDILRQGSAKAHEESQQVVNAVKTAFGLKLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYF9</accession>
    <name>D0YYF9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hydroxyacylglutathione hydrolase</fullName>
            <ecNumber evidence="2">3.1.2.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002322</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.2.6" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299864.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002322"/>
    <dbReference type="EnsemblBacteria" id="EEZ41290">
        <property type="protein sequence ID" value="EEZ41290"/>
        <property type="gene ID" value="VDA_002322"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0491">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1581636at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004416">
        <property type="term" value="F:hydroxyacylglutathione hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="14"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="217" mass="23837" checksum="D6A3ED30CD3AA9C5" modified="2010-01-19" version="1">MSLQYRIVPVTPFQQNCSIVWCDKTNQAAIIDPGGDINVIKQHVQELGLTVTKLLLTHGHLDHVGGTEPLAQELNVPVIGPQKEDIFWLQGLPRQSEMFGFPMTESFDPTQWLEDGDTVTVGEEVLSVLHTPGHTPGHVVFFSDSAKVAFVGDVLFNGGIGRTDFPRGDYQTLINSIKGKLWPLGNDVTFIPGHGPSSTFGRERASNPFVADEMPLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYL2</accession>
    <name>D0YYL2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Putrescine transporter PotE</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Putrescine-proton symporter / putrescine-ornithine antiporter</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">potE</name>
        <name evidence="6" type="ORF">VDA_002375</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes both the uptake and excretion of putrescine. The uptake of putrescine is dependent on the membrane potential and the excretion involves putrescine-ornithine antiporter activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>H(+)(in) + putrescine(in) = H(+)(out) + putrescine(out)</text>
            <dbReference type="Rhea" id="RHEA:28891"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:326268"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-ornithine(out) + putrescine(in) = L-ornithine(in) + putrescine(out)</text>
            <dbReference type="Rhea" id="RHEA:28827"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="ChEBI" id="CHEBI:326268"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell inner membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002375"/>
    <dbReference type="EnsemblBacteria" id="EEZ41343">
        <property type="protein sequence ID" value="EEZ41343"/>
        <property type="gene ID" value="VDA_002375"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0531">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015496">
        <property type="term" value="F:putrescine:ornithine antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02073">
        <property type="entry name" value="Putrescine_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027566">
        <property type="entry name" value="Symport/antiport_PotE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="5" id="KW-0050">Antiport</keyword>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0769">Symport</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="115"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="145"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="185"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="216"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="254"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="320"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="345"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="380"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="403"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="439" mass="47003" checksum="8270569E99870B0E" modified="2010-01-19" version="1">MGLIGLTTIVTVNMMGSGIILLPSSLAETGGIALLAWGVTAIGALCIAYAFAKCGMYCTEDGGMSAYSQRAHGKSSFFIASYTYYVCLVISAVAIAVSTVGYLETFIPWLKETPIHTFVGVVVVLVVTMLANVRGAKITGSISSVTVWGIIIPVLGLSVIGWFWFDPKLFAEAWNPHDVTTMTAIESGISLTLWAFLGIESAGANSGTVENPKRNVPLACMLATLFSAITYIASTTVIQGIVPNAELAKSDAPFGLVFAMMFDSTVGNIITLMAIIACAGSLLGWQFTNAQVSKAAADMRLFPKVFGEVNKHDAPIKGMMIMLVLELVLAVMTISPTLLKQFNVLVDLAVFINMVPYILSLTALGIILRQANVGAKEYSTSMIFGFVAVVYSIYGAYGTGKEAVFYGTIITLFGYLFYGFIASRDEYEKHQHQATQSNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYU2</accession>
    <name>D0YYU2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002455</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300125.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002455"/>
    <dbReference type="EnsemblBacteria" id="EEZ41423">
        <property type="protein sequence ID" value="EEZ41423"/>
        <property type="gene ID" value="VDA_002455"/>
    </dbReference>
    <dbReference type="GeneID" id="57341326"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1601931at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="226" mass="25010" checksum="3A2DC5AFF5FE5983" modified="2010-01-19" version="1">MQIAQSVVVITAAGSAIGRAMAMHFSQLGAHIALIDTDASHLQTTLECCQTLKNPCHGYLIKDLTEANIHQIGLKVLQDFGSIDILVNCWQGIVLPNLLSSHSEEHMTQALTQDSTLFFSFGRFIANYMKSNKRAGVILNVITSETLDTANYTIGNKAMIAGLTQNWAKELKHFDVRVGSIVPISYQETNTSAPLSLSMQYEMVRSAEYIVENDYFNGRIIEAEHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYX6</accession>
    <name>D0YYX6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Arginine--tRNA ligase</fullName>
            <ecNumber evidence="9">6.1.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Arginyl-tRNA synthetase</fullName>
            <shortName evidence="9">ArgRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">argS</name>
        <name evidence="13" type="ORF">VDA_002489</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg)</text>
            <dbReference type="Rhea" id="RHEA:20301"/>
            <dbReference type="Rhea" id="RHEA-COMP:9658"/>
            <dbReference type="Rhea" id="RHEA-COMP:9673"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78513"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.19"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="9">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 10">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.19" evidence="9"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300190.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002489"/>
    <dbReference type="EnsemblBacteria" id="EEZ41457">
        <property type="protein sequence ID" value="EEZ41457"/>
        <property type="gene ID" value="VDA_002489"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0018">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1146366at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004814">
        <property type="term" value="F:arginine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006420">
        <property type="term" value="P:arginyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00671">
        <property type="entry name" value="ArgRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00123">
        <property type="entry name" value="Arg_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001278">
        <property type="entry name" value="Arg-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005148">
        <property type="entry name" value="Arg-tRNA-synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036695">
        <property type="entry name" value="Arg-tRNA-synth_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035684">
        <property type="entry name" value="ArgRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008909">
        <property type="entry name" value="DALR_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11956">
        <property type="entry name" value="PTHR11956"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03485">
        <property type="entry name" value="Arg_tRNA_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05746">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00750">
        <property type="entry name" value="tRNA-synt_1d"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01038">
        <property type="entry name" value="TRNASYNTHARG"/>
    </dbReference>
    <dbReference type="SMART" id="SM01016">
        <property type="entry name" value="Arg_tRNA_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00836">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55190">
        <property type="entry name" value="SSF55190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00456">
        <property type="entry name" value="argS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arg_tRNA_synt_N" evidence="12">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="DALR_1" evidence="11">
        <location>
            <begin position="461"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="9">
        <location>
            <begin position="122"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ41457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="576" mass="64577" checksum="0ED9A5CC00B856D0" modified="2010-01-19" version="1">MNIQALINDKVSQALEAAGAPAGSPAAVRQSAKAQFGDYQANGVMGVAKQLGTNPREFAQKVIDNLDLGEMAEKVEIAGPGFINIFLNKQWLAARAEEALNDDRLSVAKEKEQTIVVDYSAPNVAKEMHVGHLRSTIIGDAVVRTLEFLGHNVIRANHLGDWGTQFGMLIANMVRKEQDGSDVSMNISDLEGFYRESKVLYDEDPEFAETARNYVVRLQSGDEYCHEKWKQLVEITLKQNQRNYDRLNVSLTDENVMGESMYNEMLPGIVADLKEKGLAVEDDGAVVVFLDEYKNKDGEPMGVIIQKRDGGYLYTTTDIACAKYRYEKLHADRVLYFIDSRQHQHLMMAWSIVRKAGYVPESVSLEHHAFGMMLGKDGRPFKTRAGGTVRLADLLDEAQERANKLIEEKNPELSAEEKAEIANTVAMAAVKYADLSKHRTTDYIFDWDNMLAFEGNTAPYMQYAYTRVASIFKRAGVELADLTHPIIITDEKEQALLSKLLQFEEAVQTVAREGHPHVMCNYLFELAGTFSSFYEACPILNAEEEVKQSRLKLAHLTAKTIKQGLDLLGIKTLDRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYZ2</accession>
    <name>D0YYZ2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002505</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GTP cyclohydrolase I type 2/NIF3 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300216.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002505"/>
    <dbReference type="EnsemblBacteria" id="EEZ41473">
        <property type="protein sequence ID" value="EEZ41473"/>
        <property type="gene ID" value="VDA_002505"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0327">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="502462at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002678">
        <property type="entry name" value="DUF34/NIF3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036069">
        <property type="entry name" value="DUF34/NIF3_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13799">
        <property type="entry name" value="PTHR13799"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01784">
        <property type="entry name" value="NIF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102705">
        <property type="entry name" value="SSF102705"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00486">
        <property type="entry name" value="YbgI_SA1388"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="252" mass="27818" checksum="1D353676AF0B891B" modified="2010-01-19" version="1">MNNIQLERLLNDFLSPQLINDYCPNGLQVEGKSEIKKIVTGVTACQELIDLAIAENADALLVHHGFFWKGEPAHLRGMKYHRIKALIENGINLYAYHLPLDVHPQVGNNVKLAQLLGIDIIGGLEQGNPRSIALYGELEQPLEASEFAARIAMTLQREPLYISGNQSQLIKTVGWCTGGGQDYIELAASQGIDAFISGEVSERTTHTAREMGIDYFAAGHHATERYGVKALGEWLAQEHGFDVQFIDVNNPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYZ6</accession>
    <name>D0YYZ6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative esterase/lipase ybfF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002509</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300223.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002509"/>
    <dbReference type="EnsemblBacteria" id="EEZ41477">
        <property type="protein sequence ID" value="EEZ41477"/>
        <property type="gene ID" value="VDA_002509"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1498437at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="14"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="253" mass="28859" checksum="AB920EBFA8BD6CD3" modified="2010-01-19" version="1">MKLHYHAIGDGYPIILIHGLFGSGDNLGLISRALKDKYKVINVDLRNHGLSPHSDQFTYQQMAQDVLDVIDELSIDHFAVIGHSMGGKVAMSLTELASDRIDHLIVLDIAPVAYSEHRHQNVFAGLREVSRHIILNRKEAEQYLALHVQDPGVRQFLLKSLTKTENGYQWRFNVEGLIANYQTIMGWHDIPPFTGKTLFMKGQDSEYITPDYREAIMRQFPNAKAHLVANTGHWLHAEKPETVNRVIEQFLQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ10</accession>
    <name>D0YZ10_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Chaperone protein HtpG</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Heat shock protein HtpG</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">High temperature protein G</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">htpG</name>
        <name evidence="7" type="ORF">VDA_002523</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Molecular chaperone. Has ATPase activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the heat shock protein 90 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300251.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002523"/>
    <dbReference type="EnsemblBacteria" id="EEZ41491">
        <property type="protein sequence ID" value="EEZ41491"/>
        <property type="gene ID" value="VDA_002523"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0326">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="246194at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00505">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019805">
        <property type="entry name" value="Heat_shock_protein_90_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037196">
        <property type="entry name" value="HSP90_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001404">
        <property type="entry name" value="Hsp90_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020575">
        <property type="entry name" value="Hsp90_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11528">
        <property type="entry name" value="PTHR11528"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00183">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002583">
        <property type="entry name" value="Hsp90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00775">
        <property type="entry name" value="HEATSHOCK90"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110942">
        <property type="entry name" value="SSF110942"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00298">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="HATPase_c" evidence="6">
        <location>
            <begin position="33"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="A; substrate-binding" evidence="5">
        <location>
            <begin position="1"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="C" evidence="5">
        <location>
            <begin position="562"/>
            <end position="633"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="633" mass="72194" checksum="9FBCCF09EFBF66E5" modified="2010-01-19" version="1">MSEQSLDKNKETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSDGSLYENDAELAVKISVNQDAGTLTISDNGIGMTREDVIEHLGTIAKSGTKEFFAKLNEEETKDSQLIGQFGVGFYSAFIVADSVTVNTRAAGVPADQAVSWSSAGEGDYTVENTTKAARGTDIILHLRDDEKEFLDEYRLRDIISKYSDHIGIPVLIQTTERDEEGNETGKKWEQINKAQALWTRNKSDISDEEFKEFYKHVSHDFAEPLTWSLNHVEGKQDYTSLLYIPSKAPWDLYHRDSQHGLKLYVQRVFIMDDAQQFMPMYLRFMRGLIDSNDLPLNVSREILQDNKVTQALRKACTKRALSMLSKLAKGDSEKYQTFWQEFGQVIKEGLAEDFANRDKIAQLLRFSSTYNDSAEQTVALADYVERMKEGQDKIYYITADNFNAAKNSPHLEQFRAKGIEVLLMHDRIDEWMMSYMPEFEGKGFQSITKSDLDLSKFEDEAEKEKHKETEEAFKSVVERTKEYLGSRVKDVRTTFKLHDTPAVVVTDENEMGTQMAKLLAAAGQEAPEVQYILELNPDHALVKQMADEADEEIFGRWVEMLFGQSLLAERGAMDDPSRFLTAMNQLLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ16</accession>
    <name>D0YZ16_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 10">Adenine phosphoribosyltransferase</fullName>
            <shortName evidence="10">APRT</shortName>
            <ecNumber evidence="5 10">2.4.2.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">apt</name>
        <name evidence="12" type="ORF">VDA_002529</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>AMP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + adenine</text>
            <dbReference type="Rhea" id="RHEA:16609"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.4.2.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Purine metabolism; AMP biosynthesis via salvage pathway; AMP from adenine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the purine/pyrimidine phosphoribosyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.7" evidence="5 10"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300263.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002529"/>
    <dbReference type="EnsemblBacteria" id="EEZ41497">
        <property type="protein sequence ID" value="EEZ41497"/>
        <property type="gene ID" value="VDA_002529"/>
    </dbReference>
    <dbReference type="GeneID" id="57341241"/>
    <dbReference type="eggNOG" id="COG0503">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1532478at2"/>
    <dbReference type="UniPathway" id="UPA00588">
        <property type="reaction ID" value="UER00646"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003999">
        <property type="term" value="F:adenine phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006168">
        <property type="term" value="P:adenine salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044209">
        <property type="term" value="P:AMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006166">
        <property type="term" value="P:purine ribonucleoside salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00004">
        <property type="entry name" value="Aden_phosphoribosyltr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005764">
        <property type="entry name" value="Ade_phspho_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01090">
        <property type="entry name" value="apt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 10 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 10" id="KW-0660">Purine salvage</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran" evidence="11">
        <location>
            <begin position="29"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ41497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="181" mass="19747" checksum="ED68568144423C9A" modified="2010-01-19" version="1">MTQEKIELIQSSIKSIQDYPKPGILFRDVTSLMENPDAYRATMEVLTERYKDKGITKIIGTEARGFLFGAPLALALGVGFVPVRKPGKLPREVIAESYELEYGKDTLEIHLDAIAEGDKVLLVDDLLATGGTIEATTNLVRRLGGVVEDAAFVINLPDIGGEERLKGLGLNVYSICDFPGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ33</accession>
    <name>D0YZ33_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Oxygen-insensitive NAD(P)H nitroreductase/dihydropteridine reductase</fullName>
            <ecNumber evidence="3">1.5.1.34</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002546</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the nitroreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.34" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300298.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41514">
        <property type="protein sequence ID" value="EEZ41514"/>
        <property type="gene ID" value="VDA_002546"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0778">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1847197at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004155">
        <property type="term" value="F:6,7-dihydropteridine reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02149">
        <property type="entry name" value="NfsB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.109.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033878">
        <property type="entry name" value="NfsB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029479">
        <property type="entry name" value="Nitroreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000415">
        <property type="entry name" value="Nitroreductase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00881">
        <property type="entry name" value="Nitroreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55469">
        <property type="entry name" value="SSF55469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitroreductase" evidence="2">
        <location>
            <begin position="8"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="217" mass="24267" checksum="5E122A6FC51441E3" modified="2010-01-19" version="1">MSIVSAAEARYSTKAFDASRKLTDKQVADLKELVRVSASSVNSQPWHFILASTDEGKAKIAKSMQGPYVFNERKALDASHVLVFCAKTDIDEQYLLELLESEDKAGRFANEEAKQGMHTGRSFFVNMHLEQLHDVQAWMEKQVYLNVGTLLLGAAAMDIDAVPIEGFDADVLDAEFGLKEKGFKSLVVVPLGFHSEEDFNAKLPKSRWEETRVFTEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ56</accession>
    <name>D0YZ56_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Long-chain fatty acid transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_002569</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell outer membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the OmpP1/FadL family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300355.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002569"/>
    <dbReference type="EnsemblBacteria" id="EEZ41537">
        <property type="protein sequence ID" value="EEZ41537"/>
        <property type="gene ID" value="VDA_002569"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2067">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="620166at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005017">
        <property type="entry name" value="OMPP1/FadL/TodX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35093">
        <property type="entry name" value="PTHR35093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03349">
        <property type="entry name" value="Toluene_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019259" evidence="8">
        <location>
            <begin position="25"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="444" mass="47491" checksum="F82C8152098EC78E" modified="2010-01-19" version="1">MNKQKITLSLAAAVALGLTSNAMAAGFQLAEYSATGLGRAFAGEAAMADNASTQFRNPAMLTYLEGTQISTGAIYVDPNIDVNGNLQLNGHTIDSTSANNIANSAVVPNFYFSRPLNDKFTLGLAVGTHFGMRTDLGTNFTGSMFGNQAEVHTVEINPNLAYKINEQFSVGAGVRYVIGKGHFGAALPSSLPKAFAAYNPMYSPLAGKNLKYMEGDDSSWGWQAGAAWQINPANRIGVSYHSAVKLDLTGHASGAAFDLKAGQRGGSYAGSLPLELPASAEIASFHQITDALAIHASVNWTDWSAFEKLEANIPSIGGQTPIKQENWKDNYRFAIGTTYQLNSKVTLRSGIAYDTAAVNDANRTQTIPETDRTWYSIGAGYKWSENLTFDAGLTYIHAKKAHLNENEPDLDHLIGNIMPGASLSFDGNTSGDVWLAGVQASYKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZE0</accession>
    <name>D0YZE0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA polymerase IV</fullName>
            <shortName evidence="2">Pol IV</shortName>
            <ecNumber evidence="2">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">dinB</name>
        <name evidence="4" type="ORF">VDA_002653</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="2">Binds 2 magnesium ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the DNA polymerase type-Y family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300611.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002653"/>
    <dbReference type="EnsemblBacteria" id="EEZ41621">
        <property type="protein sequence ID" value="EEZ41621"/>
        <property type="gene ID" value="VDA_002653"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0389">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="442163at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd03586">
        <property type="entry name" value="PolY_Pol_IV_kappa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01113">
        <property type="entry name" value="DNApol_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036775">
        <property type="entry name" value="DNA_pol_Y-fam_lit_finger_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017961">
        <property type="entry name" value="DNA_pol_Y-fam_little_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022880">
        <property type="entry name" value="DNApol_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001126">
        <property type="entry name" value="UmuC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00817">
        <property type="entry name" value="IMS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11799">
        <property type="entry name" value="IMS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100879">
        <property type="entry name" value="SSF100879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50173">
        <property type="entry name" value="UMUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="2" id="KW-0234">DNA repair</keyword>
    <keyword evidence="2" id="KW-0235">DNA replication</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0515">Mutator protein</keyword>
    <keyword evidence="2 4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="UmuC" evidence="3">
        <location>
            <begin position="14"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="113"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="18"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="site" description="Substrate discrimination" evidence="2">
        <location>
            <position position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="359" mass="40918" checksum="0045DE067EA54AFC" modified="2010-01-19" version="1">MSLISPQTEPVRKIIHVDMDCFYAAVEMRDDPELQQVPLAIGGRSERGVVSTCNYIARQYGIHSAMPTGKALKLCPHLTLVRGRMEVYKQVSQQIREIFRRYTDKIEPLSLDEAYLDVTECEMFRGSATLIAQDIRQTIERELQLTASAGIAPIKFVAKIASDMNKPNGQYVVTPEQILPFVTELKLEKIPGVGKVTLQKLHDKGLYLGKDVQNYDRTLLMQQFGKFGQSLWNRAHGIDPREVVVERKAKSVGVERTFAHNISTYDECWQVVEKLYPELEQRLQRVRPELNIAKQGVKVKFADFQQTTVEHSFPKLTKEQFAGLLQEAMTRQQGREIRLIGLSVGLEQGLKAQQLAWDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZH2</accession>
    <name>D0YZH2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphoribosylformylglycinamidine synthase</fullName>
            <shortName evidence="6">FGAM synthase</shortName>
            <shortName evidence="6">FGAMS</shortName>
            <ecNumber evidence="6">6.3.5.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Formylglycinamide ribonucleotide amidotransferase</fullName>
            <shortName evidence="6">FGAR amidotransferase</shortName>
            <shortName evidence="6">FGAR-AT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">purL</name>
        <name evidence="9" type="ORF">VDA_002685</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>ATP + H2O + L-glutamine + N(2)-formyl-N(1)-(5-phospho-beta-D-ribosyl)glycinamide = 2-formamido-N(1)-(5-O-phospho-beta-D-ribosyl)acetamidine + ADP + H(+) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17129"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:147286"/>
            <dbReference type="ChEBI" id="CHEBI:147287"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 6">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">In the N-terminal section; belongs to the FGAMS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.3" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002685"/>
    <dbReference type="EnsemblBacteria" id="EEZ41653">
        <property type="protein sequence ID" value="EEZ41653"/>
        <property type="gene ID" value="VDA_002685"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0046">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0047">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00128"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004642">
        <property type="term" value="F:phosphoribosylformylglycinamidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.650.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00419">
        <property type="entry name" value="PurL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010073">
        <property type="entry name" value="PurL_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041609">
        <property type="entry name" value="PurL_linker"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010918">
        <property type="entry name" value="PurM-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036676">
        <property type="entry name" value="PurM-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036921">
        <property type="entry name" value="PurM-like_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02769">
        <property type="entry name" value="AIRS_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18072">
        <property type="entry name" value="FGAR-AT_linker"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55326">
        <property type="entry name" value="SSF55326"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56042">
        <property type="entry name" value="SSF56042"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01735">
        <property type="entry name" value="FGAM_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="6 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 6" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FGAR-AT_linker" evidence="8">
        <location>
            <begin position="37"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="AIRS_C" evidence="7">
        <location>
            <begin position="298"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="domain" description="AIRS_C" evidence="7">
        <location>
            <begin position="702"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="6">
        <location>
            <position position="1007"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="1132"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="1134"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="173"/>
            <end position="184"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="544"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="584"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="588"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="752"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF18072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="1167" mass="127257" checksum="30348B9EC71B6EB4" modified="2010-01-19" version="1">MMEVVFTELNQAAILFTQAQPAPVEAVDILSGGRLALEKANVYLGLALADDEIDYLVESFIKLGRNPNDIELMMFAQANSEHCRHKIFNADWIIDGVEQPKSLFKMIKNTFETTPEHVLSAYKDNAAVMTGSKVGRFFPDPETRQYQYHQEDAHILMKVETHNHPTAISPWPGASTGSGGEIRDEGATGIGGKPKAGLVGFTVSNLRIPGFEQPWESDFGKPSRIVSALDIMLEGPLGGAAFNNEFGRPNLLGYFRTYEEKVTSHAGEEVRGYHKPIMIAGGLGNIRDQHVQKKEIPVGAKLIVLGGPAMNIGLGGGAASSMASGQSAEDLDFASVQRENPEMERRCQEVIDRCWQLGEQNPIAFIHDVGAGGISNALPELVDDGERGGKFDLRSVPNDEPGMSPLEIWCNESQERYVLAVAPEQMPVFEAICHRERAPFAVVGEATEERHLSLEDSHFDNMPIDMPMDILLGKPPKMQRDVVSQKVESPALECHGIELNDAIDRVLRLPAVAEKTFLITIGDRSVTGLVARDQMVGPWQIPVANCAVTAASYDTYHGEVMSMGERTPVALLDFAASARLAVGEALTNIAATDIGDIKHIKLSANWMSPAGHPGEDAGLYEAVKAVGEELCPALGLTIPVGKDSMSMKTQWQDDGQDKTVTSPLSLIITAFARVEDVRHTVTPQLRTDHGDSSLILIDLGCGQNRLGATALAQVYKQLGDKPADVDSPQLLKAFFNAIQQLVQQQNLLAYHDKGDGGLLVTLAEMAFAGHCGIKADISTLGDDALAALFNEELGAVIQVANPELDTVLSTLAAFGLDSCSHVIGSVEVSNRFDIYANGQIVVDRERNQLRTIWAEMTHKMQALRDNSSCADQEFAAKHNEQDPGLNTHLTFDLNENVAAPFNAPNINLGAKPKMAILREQGVNSHVEMAAAFDRAGFNAVDIHMSDILTGQAVLDEYQGLVACGGFSYGDVLGAGEGWAKSILFNEQAREQFERFFHRQDTLSLGVCNGCQMLSNLKELIPGAQLWPRFVRNQSERFEARFSLVEIQPSDSAFFSGMAGSRMPIAVSHGEGRVEVRDDAHLMALEQSGTVAVRYVDNLGNPTQAYPNNPNGSPNAITGLTTQDGRVTIMMPHPERVFRTVANSWHPDDWSENSPWMRMFRNARVHIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZK5</accession>
    <name>D0YZK5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein translocase subunit SecD</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">secD</name>
        <name evidence="11" type="ORF">VDA_002718</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the SecD/SecF family. SecD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002718"/>
    <dbReference type="EnsemblBacteria" id="EEZ41686">
        <property type="protein sequence ID" value="EEZ41686"/>
        <property type="gene ID" value="VDA_002718"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0342">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015450">
        <property type="term" value="F:protein-transporting ATPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043952">
        <property type="term" value="P:protein transport by the Sec complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01463_B">
        <property type="entry name" value="SecD_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005791">
        <property type="entry name" value="SecD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027398">
        <property type="entry name" value="SecD-TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022813">
        <property type="entry name" value="SecD/SecF_arch_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022645">
        <property type="entry name" value="SecD/SecF_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022646">
        <property type="entry name" value="SecD/SecF_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30081">
        <property type="entry name" value="PTHR30081"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07549">
        <property type="entry name" value="Sec_GG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13721">
        <property type="entry name" value="SecD-TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02355">
        <property type="entry name" value="SecD_SecF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00916">
        <property type="entry name" value="2A0604s01"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01129">
        <property type="entry name" value="secD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="408"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="433"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="459"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="502"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="538"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="domain" description="SecD-TM1" evidence="10">
        <location>
            <begin position="3"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ41686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="571" mass="62132" checksum="532741BBFED386CF" modified="2010-01-19" version="1">MAALDTITADLKKNHISYKSVALEKGTVLVRFNDTDTQISARDLLNQDLGEQYVVALNLAPATPKWLEDIGANPMKLGLDLRGGVHFLMEVDMDAAMEKLLGQQEDTFRTELREAKIRYRAIDKTKDSVVVRLRDAEQVEQAKNALEKLHPDMVFVENDSKGRYLLTATFTEARLQEIRNYAVDQNITILRNRVNELGVAEPLVQRQGANRIVVELPGVQDTARAKEILGATATLEFREVDSSADLGAAAAGRVPAGSEVKFTRDERPVVLKKRVILSGSHITDASSSADEYGRPQVNISLDGEGGSKMTAFSRNNVGKLMATVFTEYKDSGKRSPDGKVVLEKHEEVINQATIQTALGRNFRITGIDTQAEAHNLSLLLRAGALIAPISIVEERTIGPSMGQQNIDMGVQACIWGMVAVMIFTLVYYKAFGLIANLALAMNLVLIIGIMSMIPGATMTLPGIAGIVLTVGMAVDANVLIFERIREELREGRSPQQAIQQGYANAFSTIADANITTLITAIILFAVGTGAIKGFAVTLSIGILTSMFTAIVCTRAVVNWLYGGKRIDKLSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZL6</accession>
    <name>D0YZL6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphate-specific transport system accessory protein PhoU</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_002729</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Plays a role in the regulation of phosphate uptake.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the PhoU family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300841.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002729"/>
    <dbReference type="EnsemblBacteria" id="EEZ41697">
        <property type="protein sequence ID" value="EEZ41697"/>
        <property type="gene ID" value="VDA_002729"/>
    </dbReference>
    <dbReference type="GeneID" id="57340998"/>
    <dbReference type="eggNOG" id="COG0704">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030643">
        <property type="term" value="P:cellular phosphate ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045936">
        <property type="term" value="P:negative regulation of phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.220">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028366">
        <property type="entry name" value="P_transport_PhoU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038078">
        <property type="entry name" value="PhoU-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026022">
        <property type="entry name" value="PhoU_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42930">
        <property type="entry name" value="PTHR42930"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01895">
        <property type="entry name" value="PhoU"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003107">
        <property type="entry name" value="PhoU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02135">
        <property type="entry name" value="phoU_full"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PhoU" evidence="4">
        <location>
            <begin position="28"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="PhoU" evidence="4">
        <location>
            <begin position="129"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR003107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="236" mass="26730" checksum="E466A1E0DD773623" modified="2010-01-19" version="1">MLSNISLGRHISGQFNHELESIRTHVLAMGGLVEQQLADALKALHKQDADLAKRVIIEDHKVNSMEVAIDEACTRIIAKRQPTASDLRLVIAIIKTITDLERIGDVAESIAKVALESFSNKQYNLLVSLESLGQHTVRMLHEVLDAFARMDVKAAIEVYQEDDRIDQEYESIVRQLMAHMMEDPSSIPNVMKVMWAARSIERVGDRCQNICEYIIYFVKGKDVRHTKPDDFGTMLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZV3</accession>
    <name>D0YZV3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GGDEF and EAL domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_002816</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301089.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002816"/>
    <dbReference type="EnsemblBacteria" id="EEZ41784">
        <property type="protein sequence ID" value="EEZ41784"/>
        <property type="gene ID" value="VDA_002816"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2199">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2200">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.270.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032244">
        <property type="entry name" value="LapD_MoxY_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042461">
        <property type="entry name" value="LapD_MoxY_peri_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16448">
        <property type="entry name" value="LapD_MoxY_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="145"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="3">
        <location>
            <begin position="172"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="2">
        <location>
            <begin position="402"/>
            <end position="640"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="640" mass="72257" checksum="717E4C34BB0B1D41" modified="2010-01-19" version="1">MSLYKQCSLMLLGLLVFVFSIAGYFQLKEVKELVNNQLQAELVNTIHNISIATVTPLEMGDNQSIEQIITPQQPRNLAEIHLTSLVDGQVYQWQKAIEESTSVPSWFTQWIAWSNLEQQRTIKAGWLELASLTVSINPSWAYLQLWYYFLAIACTFISVVIAALLIMSWGWQRLMSRLDVLTQHTQQVAKHEKSHVSVERALPELDGITQAINLMAKQLNNYIQLSNQEIQSLRLQKQIDKRSGLANAEYFYDRMNSWLDEPVAGALAIIDCAWLEQIHEQYGSVVYQDSLRLLAQSLQKRCLKSTVLAQLNRSQLAIILTEHTVKEQQQEIQYIVQDIQNEIEQSEISNGEFFIGVSSKTDASTKNSLYQETLSALNYAQEHHQKVHWADNTVTHYHGLAVLNWATSIEQAITDRALVFKSQPIQNIATTATVQNEVFCQLLLGDERVVAKTFMPYVEEYGLGERLDQCILQMIEQASLLAHSGSTIAINLTVNSIRSSSFQSWLAHFLNESAMSDKLSFEVPESAIEEDLSACLSLALLFNQKDISWGIDHYGRQLTSVDYLLSLRPKYVKLDQSFAGVSTESGKYELGRALASIAAGLDIKVIATGIQYSEQLALLEGLPIWRYQGFIAPPVELNLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z000</accession>
    <name>D0Z000_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative sigma-54 dependent transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_002863</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002863"/>
    <dbReference type="EnsemblBacteria" id="EEZ41831">
        <property type="protein sequence ID" value="EEZ41831"/>
        <property type="gene ID" value="VDA_002863"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2204">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="123059at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002197">
        <property type="entry name" value="HTH_Fis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045343">
        <property type="entry name" value="VpsR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02954">
        <property type="entry name" value="HTH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00158">
        <property type="entry name" value="Sigma54_activat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20161">
        <property type="entry name" value="VpsR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01590">
        <property type="entry name" value="HTHFIS"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50045">
        <property type="entry name" value="SIGMA54_INTERACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="5">
        <location>
            <begin position="146"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="438" mass="49647" checksum="8EAD32BF54B79CCB" modified="2010-01-19" version="1">MRTSFRFESDVSHLFVFGSIESSCLTALEQSEWQCHFCHDMRMAESVLLELGPCIGLVDLSQSYFSLHSFASLLNRHKQVRWIALIDEKQLNNEAVCQFIVNFCFDYFSLPIPIPQLLTTIGHQCGMLALERYVWPELRQLGQIGLQGDSAVMRKLQNQVTRTALSDLPVFIQGEIGTGKELVAQAIHRGSIRAKYPFIRVNCRELLAGWNIETADGVKNCLMAAQGGVLFLDDIVHLSLEHQAQLLQILELGYYQNSDQERLFIDIRMMASTTVSHQELLVSGKLMTELYYRLNIVSITVPPLRERGDDIVSLARLLLLQYSRQYNGVAQCFSDDALNALRQYPWPGNVRELVSKLKRVALLADHQCVGSELLELPGSQEDTHSLKQARADSDRAAVIKVLENNHNQITASARELGISRATMYRLLKKYDLHPNKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z021</accession>
    <name>D0Z021_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Aerobic respiration control protein ArcA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_002884</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301270.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002884"/>
    <dbReference type="EnsemblBacteria" id="EEZ41852">
        <property type="protein sequence ID" value="EEZ41852"/>
        <property type="gene ID" value="VDA_002884"/>
    </dbReference>
    <dbReference type="GeneID" id="57340824"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="817710at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="5"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="134"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="134"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="239" mass="27411" checksum="5A8843E5A900BDC5" modified="2010-01-19" version="1">MQTPHILIVEDEHVTRNTLKSIFEAEGYTVFEANDGNEMHQMLSEHPVHLVIMDINLPGKNGLLLARELREQGDMALMFLTGRDNEVDKILGLEIGADDYITKPFNPRELTIRARNLLSRAMNQGMPVEDKKLVERYSFNGWSLEINSRSLVSPSGDQFKLPRSEFRALLHFCENPGKIQTRADLLKKMTGRELKPHDRTVDVTIRRIRKHFESISDTPEIIATIHGEGYRFCGDLEQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z066</accession>
    <name>D0Z066_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Aspartate carbamoyltransferase</fullName>
            <ecNumber evidence="6">2.1.3.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Aspartate transcarbamylase</fullName>
            <shortName evidence="6">ATCase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">pyrB</name>
        <name evidence="10" type="ORF">VDA_002929</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>carbamoyl phosphate + L-aspartate = H(+) + N-carbamoyl-L-aspartate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20013"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:32814"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="EC" id="2.1.3.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 6">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.3.2" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301374.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002929"/>
    <dbReference type="EnsemblBacteria" id="EEZ41897">
        <property type="protein sequence ID" value="EEZ41897"/>
        <property type="gene ID" value="VDA_002929"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0540">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1844275at2"/>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00116"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016597">
        <property type="term" value="F:amino acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004070">
        <property type="term" value="F:aspartate carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1370">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00001">
        <property type="entry name" value="Asp_carb_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006132">
        <property type="entry name" value="Asp/Orn_carbamoyltranf_P-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006130">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036901">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002082">
        <property type="entry name" value="Asp_carbamoyltransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006131">
        <property type="entry name" value="Asp_carbamoyltransf_Asp/Orn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11405:SF16">
        <property type="entry name" value="PTHR11405:SF16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00185">
        <property type="entry name" value="OTCace"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02729">
        <property type="entry name" value="OTCace_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00100">
        <property type="entry name" value="AOTCASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53671">
        <property type="entry name" value="SSF53671"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00670">
        <property type="entry name" value="asp_carb_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00097">
        <property type="entry name" value="CARBAMOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="OTCace_N" evidence="9">
        <location>
            <begin position="8"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="OTCace" evidence="8">
        <location>
            <begin position="155"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ41897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="309" mass="34571" checksum="4C6B9198B767D230" modified="2010-01-19" version="1">MPNSLFQKHIISIPEFTRDELELVVETAGKLKAEPNPELLKNKVVASCFFEPSTRTRLSFETAVQRLGGTVIGFDNGGNTSLAKKGETLADSVQVISSYVDAFVMRHPQEGAARLASEFSNGVPIINGGDGANQHPTQTLLDLFTIQETQGRLDDISIAFVGDLKYGRTVHSLTQALSKFNNVRFYFIAPEVLAMPEYICEELDDAGITYSLHSNIEEVLPELDILYMTRVQKERFDESEYAHIKSAFVLNAKMLEEARPNMKVMHPLPRIDEITTDVDKTPHAYYFQQAENGVYARQALLALVLNEQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0D4</accession>
    <name>D0Z0D4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein YtfJ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002997</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002997"/>
    <dbReference type="EnsemblBacteria" id="EEZ41965">
        <property type="protein sequence ID" value="EEZ41965"/>
        <property type="gene ID" value="VDA_002997"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3054">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006513">
        <property type="entry name" value="CHP01626_YtfJ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09695">
        <property type="entry name" value="YtfJ_HI0045"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01626">
        <property type="entry name" value="ytfJ_HI0045"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018779" evidence="1">
        <location>
            <begin position="22"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="185" mass="20333" checksum="705B3D32FE177CD5" modified="2010-01-19" version="1">MMNKKPLALLFFTLLSSSVSAHNLKLGESLPQVKVQDKGEIVLNKKDDIYYQSWSTQKLAGKVHIIQAIAGRSSAKEMNASVVSAITQAKFPADKYQTITIINQDDSIWGTGSLVKSSAEDSKKEFPWSSLVLDAKGKVQQSWQLEKDNSAIIVIDKAGKILFAQEGKLSPQQVTKVIELTKANL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0E4</accession>
    <name>D0Z0E4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003008</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301552.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003008"/>
    <dbReference type="EnsemblBacteria" id="EEZ41975">
        <property type="protein sequence ID" value="EEZ41975"/>
        <property type="gene ID" value="VDA_003008"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG50331R8">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1601636at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021302">
        <property type="entry name" value="DUF2780_VcgC/VcgE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11075">
        <property type="entry name" value="DUF2780"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018780" evidence="1">
        <location>
            <begin position="25"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="160" mass="16634" checksum="0DA05A710102F1D2" modified="2010-01-19" version="1">MNKRHTLTALAVIGMLTTSTMSYAFSLSDIFGGSDVQQTTSAIANNPLTQLLTNKLGVSPQQAAGGASALLAFASSELQGDQAKELQNLIPGSKALADAIPAGLSGLLDDPSTLNKVFSILGIDSKTADEFAPVIMQFLKQQGANQNLLTTLANVWAPTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0T1</accession>
    <name>D0Z0T1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cytochrome c4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_003145</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="4">Binds 2 heme c groups covalently per subunit.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301995.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003145"/>
    <dbReference type="EnsemblBacteria" id="EEZ42112">
        <property type="protein sequence ID" value="EEZ42112"/>
        <property type="gene ID" value="VDA_003145"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2863">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1853490at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024167">
        <property type="entry name" value="Cytochrome_c4-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00034">
        <property type="entry name" value="Cytochrom_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000005">
        <property type="entry name" value="Cytochrome_c4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4 6" id="KW-0349">Heme</keyword>
    <keyword evidence="3 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018742" evidence="7">
        <location>
            <begin position="19"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="8">
        <location>
            <begin position="20"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="8">
        <location>
            <begin position="114"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="binding site" description="covalent" evidence="4">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="4">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="4">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="4">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>2</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>2</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000005-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000005-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ42112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="205" mass="21717" checksum="6074DA69A4EA8053" modified="2010-01-19" version="1">MNKLIVILGLLASLPTWAQGDVAAGKAKSVTCAACHGADGNGILPQYPKLSGQHAPYLEKQLHDFKLAMSSGGEQGRVDAVMGGMVMPLSEQDMADLAAYYASLPISDNTSAKASIPIGQQLYRFGDSERGIPACSACHGPRGDGTSLSGFPKISGQNAEYIQLQLEKFRDGQRANDMNAMMRSVASKLNDQEITALSQYVGGLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0W2</accession>
    <name>D0Z0W2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">3-octaprenyl-4-hydroxybenzoate carboxy-lyase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Polyprenyl p-hydroxybenzoate decarboxylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_003176</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302080.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003176"/>
    <dbReference type="EnsemblBacteria" id="EEZ42143">
        <property type="protein sequence ID" value="EEZ42143"/>
        <property type="gene ID" value="VDA_003176"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0043">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1012819at2"/>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002830">
        <property type="entry name" value="UbiD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30108">
        <property type="entry name" value="PTHR30108"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01977">
        <property type="entry name" value="UbiD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00148">
        <property type="entry name" value="TIGR00148"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00018597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ42143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="618" mass="69526" checksum="D6481D14A00AE087" modified="2010-01-19" version="1">MKFQDLRDFIDYLEAQGQLKRISHPVDPNQEITEICDRTLRAKGPALLFENPIGYDIPVLANLFGTPERVAMGMGRTDVKELRQVGEWLAYLKEPEPPQGLRDAFNKLPVFKQVLNMPVKRLRKAPCQEVVWQGDEVDLDKIPVMSCWPDDVAPLLTWGLTITKGPNKKRQNLGIYRQQKIAKNKVIMRWLAHRGGALDLRDWMETHPGQPFPVTVAFGADPATILGAVTPVPDTLSEYAFAGLLRGRRTEVVKSLSNDLDIPASAEIVMEGYIDPNEFALEGPYGDHTGYYNETEQHHVFTITHLSMKQKPIYHSTYTGRPPDEPAVLGVALNEVFVPILQKQFPEIEDFYLPPEGCSYRMAVVTIKKQYPGHAKRIMMGVWSFLRQFMYTKYVVICDHDVDARSWDSVIPAITANMDPVTDSLFIDHTPIDSLDFASPVVGLGSKMGLDATRKWPAELIGRSPDCSVTEVIDLIAKEAQLRETYPQIIDCYFPPQAKDHSMALVSIDKQAVGDGKAMIEALWHQMSQFTTPKFVIICDGDVNVRDWNDVIWAITTRMDPTRDTISVPAGATSSKMGLDATNKLPGETEREWGTPIVKDRKIVAKIDAIWEQLAIIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0Y1</accession>
    <name>D0Z0Y1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Shikimate dehydrogenase (NADP(+))</fullName>
            <shortName evidence="8">SDH</shortName>
            <ecNumber evidence="3 8">1.1.1.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">aroE</name>
        <name evidence="12" type="ORF">VDA_003195</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>NADP(+) + shikimate = 3-dehydroshikimate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:17737"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16630"/>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.25"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 4/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the shikimate dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.25" evidence="3 8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302128.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003195"/>
    <dbReference type="EnsemblBacteria" id="EEZ42162">
        <property type="protein sequence ID" value="EEZ42162"/>
        <property type="gene ID" value="VDA_003195"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0169">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1054867at2"/>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00087"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004764">
        <property type="term" value="F:shikimate 3-dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019632">
        <property type="term" value="P:shikimate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00222">
        <property type="entry name" value="Shikimate_DH_AroE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041121">
        <property type="entry name" value="SDH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011342">
        <property type="entry name" value="Shikimate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013708">
        <property type="entry name" value="Shikimate_DH-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022893">
        <property type="entry name" value="Shikimate_DH_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006151">
        <property type="entry name" value="Shikm_DH/Glu-tRNA_Rdtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21089">
        <property type="entry name" value="PTHR21089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18317">
        <property type="entry name" value="SDH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01488">
        <property type="entry name" value="Shikimate_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08501">
        <property type="entry name" value="Shikimate_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00507">
        <property type="entry name" value="aroE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="5 8" id="KW-0521">NADP</keyword>
    <keyword evidence="6 8 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Shikimate_dh_N" evidence="10">
        <location>
            <begin position="6"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="Shikimate_DH" evidence="9">
        <location>
            <begin position="116"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="SDH_C" evidence="11">
        <location>
            <begin position="239"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Shikimate binding" evidence="8">
        <location>
            <begin position="14"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="65"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>shikimate</name>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>shikimate</name>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>shikimate</name>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="126"/>
            <end position="130"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="150"/>
            <end position="155"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="215"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="217"/>
        </location>
        <ligand>
            <name>shikimate</name>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>shikimate</name>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF18317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ42162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="275" mass="29511" checksum="48C293A4568ED66B" modified="2010-01-19" version="1">MDKYAVFGHPIAQSKSPYIHTLFARQTGQQMSYEAILAPLDGFQTALDDFLAAGGRGCNITVPFKEQAYRVATQLTERARLAGAVNTLKLLDDGVLLGDNTDGEGLVQDLLAHQVTLENQRILLIGAGGAARGVILPLLAQNPQQLVIANRTYDKAQALADTFATFGNITAMDNETLALQDGFDVVINSTSASLSGSVPDVPTSVITHHSCCYDMVYGAQPTAFNNWTSTLGASKNLDGLGMLVGQAAESFMLWRGLRPGAKQVQRELRRSLQGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z100</accession>
    <name>D0Z100_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Thiol:disulfide interchange protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">VDA_003214</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the thioredoxin family. DsbA subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302184.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003214"/>
    <dbReference type="EnsemblBacteria" id="EEZ42181">
        <property type="protein sequence ID" value="EEZ42181"/>
        <property type="gene ID" value="VDA_003214"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1651">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1805428at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015036">
        <property type="term" value="F:disulfide oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd03019">
        <property type="entry name" value="DsbA_DsbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001853">
        <property type="entry name" value="DSBA-like_thioredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023205">
        <property type="entry name" value="DsbA/DsbL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01323">
        <property type="entry name" value="DSBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001488">
        <property type="entry name" value="Tdi_protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 8" id="KW-0574">Periplasm</keyword>
    <keyword evidence="7" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018796" description="Thiol:disulfide interchange protein" evidence="10">
        <location>
            <begin position="21"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="11">
        <location>
            <begin position="7"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="9">
        <location>
            <begin position="50"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR001488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001488-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ42181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="200" mass="22449" checksum="839FB820A70446C6" modified="2010-01-19" version="1">MIKKLLTLASAALLSLSVHAAKFTEGDYYKVLDRPESTTPMVTEFFSFYCPHCNSFEPMMQALKKTLPENATFQKEHVSFMGGPMGKVLSKAYATAIVLDVQDKLTPVLFNRIHEMRKPPRNEAEVRQIFIDEGVKPADFDGAYNSFAVNSMVSRFDKDFEDSGLTGVPAVIVNNKYLVEAGKITSAQEYFDLVNFLLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z132</accession>
    <name>D0Z132_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Amino acid ABC transporter amino acid-binding portion</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_003246</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial solute-binding protein 3 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302276.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003246"/>
    <dbReference type="EnsemblBacteria" id="EEZ42213">
        <property type="protein sequence ID" value="EEZ42213"/>
        <property type="gene ID" value="VDA_003246"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0834">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1632224at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015276">
        <property type="term" value="F:ligand-gated ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001320">
        <property type="entry name" value="Iontro_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018313">
        <property type="entry name" value="SBP_3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00062">
        <property type="entry name" value="PBPb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00079">
        <property type="entry name" value="PBPe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01039">
        <property type="entry name" value="SBP_BACTERIAL_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018751" evidence="5">
        <location>
            <begin position="25"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="PBPb" evidence="6">
        <location>
            <begin position="27"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="PBPe" evidence="7">
        <location>
            <begin position="27"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ42213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="251" mass="28197" checksum="818C23518CABBE38" modified="2010-01-19" version="1">MKISQSLRFAAITFALIGSSSIFAATEVKVGMSGRYFPFTFVKQDQLQGFEVDLWQEIGKRNDYKVDFVTANFSGLFGLLETGRIDTISNQITITPERQNKFLFSQPYVIDGAQLVVRKGNNAITSTSDLNGKTVGVNLGSNYEQLLRQLPNADQINIKTYDTGIEHDVALGRTDTFVMDRLSSLEVIKKVNLPLQLAGQPFEQIENAWPFSRTEKGKKLQQEVNQALANMRKDGTLRQLSEKWFASDITQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z163</accession>
    <name>D0Z163_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Bcr/CflA family efflux transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_003277</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell inner membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Bcr/CmlA family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302364.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003277"/>
    <dbReference type="EnsemblBacteria" id="EEZ42244">
        <property type="protein sequence ID" value="EEZ42244"/>
        <property type="gene ID" value="VDA_003277"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1452500at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990961">
        <property type="term" value="P:xenobiotic detoxification by transmembrane export across the plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004812">
        <property type="entry name" value="Efflux_drug-R_Bcr/CmlA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00710">
        <property type="entry name" value="efflux_Bcr_CflA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="103"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="167"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="214"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="251"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="281"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="306"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="338"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="369"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="8">
        <location>
            <begin position="12"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ42244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="400" mass="42930" checksum="DBE4D8D32BC172B2" modified="2010-01-19" version="1">MSQPSSLKNTRLVALMVLLVLFSPLAIDIYLPALPAMAETFSVTGTQVQDTVTWFMVSLGLGQLLAGPLADRFGRRPIALGGVVIYAISALVAYGAQTLDLLLLARLCQGFGACATSVAAFAAVRDSFGAEKSGRMISYLNGAICFIPALAPLLGTWLTHHFGWRSNFSFMAGFAVIAGTLLWVLFKETRPAETQTSGALISWSRYFSVLREPVFLFHAILCMLAMAVILAYVTSAPVWLMMKQGQTMNQFTFWFGLNAALNIAACMLAPKVMDKLGSRATLQIGLIILLLAGGAMLVMANIMQPWAFMVPIFVSSFGFAFVLGSAAGKALAPFGDRAGTAAALLGLFQMSGAGAMVSLTQRLDLTPPYLMTLQMWLLIPGLLILVSKLGRRWHAAPSLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1F2</accession>
    <name>D0Z1F2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Rhodanese domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003366</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003366"/>
    <dbReference type="EnsemblBacteria" id="EEZ42333">
        <property type="protein sequence ID" value="EEZ42333"/>
        <property type="gene ID" value="VDA_003366"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0607">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="28"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="124" mass="13601" checksum="86F5C3E21E846653" modified="2010-01-19" version="1">MAIIASLVKQKTAGYQVVTANDATLLVNREEGVFVDIRSQEEFRKGHIAGSVHILPSQIKDQNFANLENYKDAPIVVVCKTGQTAQESANLLHKAGFTKVNLLKDGLISWNEANLPLVRGKSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1F8</accession>
    <name>D0Z1F8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional regulatory protein CpxR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_003372</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302592.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003372"/>
    <dbReference type="EnsemblBacteria" id="EEZ42339">
        <property type="protein sequence ID" value="EEZ42339"/>
        <property type="gene ID" value="VDA_003372"/>
    </dbReference>
    <dbReference type="GeneID" id="57340178"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="817710at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="3"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="128"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="128"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ42339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="229" mass="26064" checksum="BE5081360667DD56" modified="2010-01-19" version="1">MAKVLLVDDDTELTALLHDILEMEGFEVEQANNGEQGLEKINASIDLVLLDVMMPKMNGTEMLRRLREKYSTPVLMLTAKGDEIDRVLGLELGADDYLPKPFSDRELLARMRAILRRTQALDNRVTHGDTIDYQDITIYPGRQEAFCQNRALDVTGTELALLSYFIQHPGKIISKEELSLEVLGKRLAQFDRAIDMHVSNLRKKLPERLDDKPRIKTLRGKGYLLVEEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1G7</accession>
    <name>D0Z1G7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Glycerol uptake facilitator protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_003381</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the MIP/aquaporin (TC 1.A.8) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003381"/>
    <dbReference type="EnsemblBacteria" id="EEZ42348">
        <property type="protein sequence ID" value="EEZ42348"/>
        <property type="gene ID" value="VDA_003381"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0580">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015267">
        <property type="term" value="F:channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00333">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022357">
        <property type="entry name" value="MIP_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00783">
        <property type="entry name" value="MINTRINSICP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="SSF81338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00861">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00221">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="79"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="138"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="171"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="223"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ42348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="274" mass="28531" checksum="2F4390AD9809AFA9" modified="2010-01-19" version="1">MGECIAEFIGTGLLIFFGVGCVAALKLTGADFGQWEVSVMWGLGVALAIYCTAGVSGAHLNPAVTLALAAFHGFDKRKIAPFIIAQLLGAFCSAALIYGLYSNLFTEYEATHQIVRGSQESLATAGIFSTYPHAALSFFGAFAVEFTITAVLMFAILAIGDQKNGAARGALGPILIGVLIAVIGGSLGPLTGFAMNPARDFGPKFFAFLAGWGDMALTGGKDIPYFIVPILAPICGALFGGWLYPKAIGVYLPGNNCTLPNQCEGAEEIKQEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1H2</accession>
    <name>D0Z1H2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ATP-dependent protease subunit HslV</fullName>
            <ecNumber evidence="7">3.4.25.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">hslV</name>
        <name evidence="8" type="ORF">VDA_003386</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP-dependent cleavage of peptide bonds with broad specificity.</text>
            <dbReference type="EC" id="3.4.25.2"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="7">Allosterically activated by HslU binding.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase T1B family. HslV subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.4.25.2" evidence="7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302619.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003386"/>
    <dbReference type="MEROPS" id="T01.006"/>
    <dbReference type="EnsemblBacteria" id="EEZ42353">
        <property type="protein sequence ID" value="EEZ42353"/>
        <property type="gene ID" value="VDA_003386"/>
    </dbReference>
    <dbReference type="GeneID" id="57340164"/>
    <dbReference type="eggNOG" id="COG5405">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1129370at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009376">
        <property type="term" value="C:HslUV protease complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005839">
        <property type="term" value="C:proteasome core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004298">
        <property type="term" value="F:threonine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01913">
        <property type="entry name" value="protease_HslV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00248">
        <property type="entry name" value="HslV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022281">
        <property type="entry name" value="ATP-dep_Prtase_HsIV_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="PTHR32194"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039093">
        <property type="entry name" value="HslV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03692">
        <property type="entry name" value="ATP_dep_HslV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 7 8" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0915">Sodium</keyword>
    <keyword evidence="4 7" id="KW-0888">Threonine protease</keyword>
    <feature type="active site" evidence="7">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ42353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="175" mass="19087" checksum="39074F126EB59A35" modified="2010-01-19" version="1">MTTIVSVRRNGKVVIAGDGQVSLGNTVMKGNARKVRRLYNNKVLAGFAGGTADAFTLFERFERKLEMHQGHLLKAAVELAKDWRTDRMLRKLEALLAVADETGSLIITGNGDVVQPENDLIAIGSGGNFAQAAARALLENTDLDAREIAEKSLNIAGDICVFTNHHHTIEELDYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1P7</accession>
    <name>D0Z1P7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">30S ribosomal protein S13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpsM</name>
        <name evidence="8" type="ORF">VDA_003461</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uS13 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303495.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003461"/>
    <dbReference type="EnsemblBacteria" id="EEZ42428">
        <property type="protein sequence ID" value="EEZ42428"/>
        <property type="gene ID" value="VDA_003461"/>
    </dbReference>
    <dbReference type="GeneID" id="57340082"/>
    <dbReference type="eggNOG" id="COG0099">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1772647at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.910.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01315">
        <property type="entry name" value="Ribosomal_S13_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027437">
        <property type="entry name" value="30s_Rbsml_prot_S13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001892">
        <property type="entry name" value="Ribosomal_S13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010979">
        <property type="entry name" value="Ribosomal_S13-like_H2TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019980">
        <property type="entry name" value="Ribosomal_S13_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018269">
        <property type="entry name" value="Ribosomal_S13_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10871:SF1">
        <property type="entry name" value="PTHR10871:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00416">
        <property type="entry name" value="Ribosomal_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002134">
        <property type="entry name" value="Ribosomal_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46946">
        <property type="entry name" value="SSF46946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03631">
        <property type="entry name" value="uS13_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00646">
        <property type="entry name" value="RIBOSOMAL_S13_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50159">
        <property type="entry name" value="RIBOSOMAL_S13_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="5" id="KW-0820">tRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="94"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ42428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="118" mass="13278" checksum="61A37305BB18621D" modified="2010-01-19" version="1">MARIAGINIPDQKHAVIALTAIYGIGKTRSQAILAETGIAEDVKISELTEEQIDLLRDGVAKYTVEGDLRREVSMNIKRLMDLGCYRGLRHRRSLPLRGQRTKTNARTRKGPRKPIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1S7</accession>
    <name>D0Z1S7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">MSHA biogenesis protein MshH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_003491</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303593.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003491"/>
    <dbReference type="EnsemblBacteria" id="EEZ42458">
        <property type="protein sequence ID" value="EEZ42458"/>
        <property type="gene ID" value="VDA_003491"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2199">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2200">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033423">
        <property type="entry name" value="GAPES4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17157">
        <property type="entry name" value="GAPES4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="3">
        <location>
            <begin position="258"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="2">
        <location>
            <begin position="401"/>
            <end position="646"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ42458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="646" mass="73229" checksum="83B5E999BEDDDBE4" modified="2010-01-19" version="1">MRRASGMKLSNRLVAFVTVIVLSAIFVIFIGGALSFRTLGLSYQDHYLQGIVDVIEQEVNDASDAHGQKHLARWLPKLLQASNVIDLTVEYNNQTYYHYTQPDPLADPNLLYRTHYTLGKTGSVIVNIASIPPYTELTYSIGPMSSISLAILIIIIGLVRGVNWLRRQLTGSEMLEERGRMILAGRVDQYAEGKEQEWPGTASLALDQLIAELKDARQERSRFDTFIRTHTFLDQLTGAANRVLFDSRLQSMVQEPDSQGVVILIRIDDWDELQNERGKEVADEFIQDVGVVLTNFSQRYPDTLLARYFDAEFAMLIPQQSAKEIKLFTNQMLHALERIKPSAPMELDNWFHIGVTYYQTGERRGRIMDEADMALRSAQLQRCNSWCTFKKDQQFAEGRGSVRWRSLLDAILNQGGPLLFQQAVFIADKDQILHRELLARIQDENGILMKASGFIPAVNMVGFNVRFDRSVVTKALALLQTLPAQEALSVNLSVEALLDKNFSRWLRDQLLQTPRTVLNRLSFEVPESQLVKHLDAMRPILRMVAGLGCQLVIDQAGKTIVSTHYIKDIKADYIKLHRGLVRDIHQRQENQLFVRSMLGACEITKAKLIAVGVESDKEWQVLKQLGVYGGQGRLFAAELSVNRIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1X8</accession>
    <name>D0Z1X8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal RNA small subunit methyltransferase I</fullName>
            <ecNumber evidence="6">2.1.1.198</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">16S rRNA 2'-O-ribose C1402 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">rRNA (cytidine-2'-O-)-methyltransferase RsmI</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rsmI</name>
        <name evidence="8" type="ORF">VDA_003542</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>cytidine(1402) in 16S rRNA + S-adenosyl-L-methionine = 2'-O-methylcytidine(1402) in 16S rRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42924"/>
            <dbReference type="Rhea" id="RHEA-COMP:10285"/>
            <dbReference type="Rhea" id="RHEA-COMP:10286"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74495"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.198"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the methyltransferase superfamily. RsmI family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.198" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303744.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003542"/>
    <dbReference type="EnsemblBacteria" id="EEZ42509">
        <property type="protein sequence ID" value="EEZ42509"/>
        <property type="gene ID" value="VDA_003542"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0313">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1059309at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070677">
        <property type="term" value="F:rRNA (cytosine-2'-O-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000453">
        <property type="term" value="P:enzyme-directed rRNA 2'-O-methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd11648">
        <property type="entry name" value="RsmI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01877">
        <property type="entry name" value="16SrRNA_methyltr_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008189">
        <property type="entry name" value="rRNA_ssu_MeTfrase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018063">
        <property type="entry name" value="SAM_MeTrfase_RsmI_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46111">
        <property type="entry name" value="PTHR46111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005917">
        <property type="entry name" value="MTase_YraL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="SSF53790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00096">
        <property type="entry name" value="TIGR00096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01296">
        <property type="entry name" value="RSMI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TP_methylase" evidence="7">
        <location>
            <begin position="13"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ42509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="286" mass="31405" checksum="63958FCAA9DC60D4" modified="2010-01-19" version="1">MSETTSCSVDVATLYIVPTPIGNLADITQRALDVLANVDLIAAEDTRHTSRLLSHFSISTRTFALHDHNEQQKADFLIEKLQSGVSIALVSDAGTPLISDPGYHFVNRCRQAGVKVVPLPGPCAVITALSGAGLPSDRFSFEGFLPPKSKGRRDCFQNLADDERTLIFYESPHRITDSLADMLAVLGPERQVVLARELTKTYETIYGAPLGELIEWLNQDTNRLRGEMVLLVAGHRPQKDDLPADALRTLGLLVKELPLKKASALAAEIHNVKKNALYKWGLENLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1Z1</accession>
    <name>D0Z1Z1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">LysR-family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001977</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299071.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001977"/>
    <dbReference type="EnsemblBacteria" id="EEZ40945">
        <property type="protein sequence ID" value="EEZ40945"/>
        <property type="gene ID" value="VDA_001977"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1591366at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08417">
        <property type="entry name" value="PBP2_Nitroaromatics_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037402">
        <property type="entry name" value="YidZ_PBP2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="9"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="306" mass="35061" checksum="2714B8C95514C812" modified="2010-01-19" version="1">MDLIKLSRISMKHLITLHIMLDTLSVTATAERLCLSPSSVSKTLNQLRDNLNDDLFYRHGNKLIATPLARRLGPTVRQMINDMNQIMTAEVFDVSQYQGRFSIAMRESTFDLLAAQLSQNIIAQAPHIRLDIWSKDSIGFDGLRKGILDFVILPHDRSQPPLNSQSHLVWETLMTDEMICLMNPNHPLAQQEMTIERYLSQNHIGIMDNDLNQPFFELQLTQEHQSRQVTVTVADFGAAATLCQYSNLLFTCSRRWAETAIIAKDLVVKPLPFNYGEVAYSLVWHEPSMNDPAHRWMYEQIVKCAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z200</accession>
    <name>D0Z200_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Hypothetical membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_001986</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299099.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001986"/>
    <dbReference type="EnsemblBacteria" id="EEZ40954">
        <property type="protein sequence ID" value="EEZ40954"/>
        <property type="gene ID" value="VDA_001986"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2194">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1067869at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008484">
        <property type="term" value="F:sulfuric ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016772">
        <property type="term" value="F:transferase activity, transferring phosphorus-containing groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012549">
        <property type="entry name" value="EptA-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040423">
        <property type="entry name" value="PEA_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30443">
        <property type="entry name" value="PTHR30443"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08019">
        <property type="entry name" value="EptA_B_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="9"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="71"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="113"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="147"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="EptA_B_N" evidence="9">
        <location>
            <begin position="52"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="8">
        <location>
            <begin position="229"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ40954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="534" mass="60537" checksum="A00A5FF83B0E15B9" modified="2010-01-19" version="1">MKLRLSSTAYIALIALFFTLIQNIGLWHHLSDLFSKEPPHSWIFVATIPLFIFFALNIIFTLLIWPVAHRILIPIIIILSSLATYGMYTYGTFFDYGMIVNIFETNTGEATSYLSWGLVPWFLIICVLPIVVLSLTKVVFKPFWKELLSKLISIVVSVIVIAVIAGFYYKDYASLVRNHSEIKALLNPTNYITATYRYGRYQLVEAHMPFKHLGEDAVDTNKSGRPNVVVMVLGEASRSMNYSLNGYKRDTNPQLSQRDVISFKNVQSCGTATAVSVPCMFSDMTRATYNPTTVRHQDSVIDVLNHAGINLLWKDNDGGCKGVCDRIKHIEMTAKIDPSLCHNGSCYDQILLNKLQQFIDEQKQDTLIVIHLIGSHGPTYDDRYPAKFKHFTPTCDTSDLQNCTREQVTNTYDNSILYTDHILSQVVDILKADDKHANTAMIYMADHGESLGEDGIYLHGLPYSIAPKEQTTVPLILWLSPSYEKSQKINRQCLIKESNQGGITQDNLFHTLLGMMDVKTKIYQPKLDIFNQCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z236</accession>
    <name>D0Z236_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DedA protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001863</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the DedA family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298834.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40831">
        <property type="protein sequence ID" value="EEZ40831"/>
        <property type="gene ID" value="VDA_001863"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0586">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1928533at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032818">
        <property type="entry name" value="DedA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032816">
        <property type="entry name" value="SNARE_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30353">
        <property type="entry name" value="PTHR30353"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09335">
        <property type="entry name" value="SNARE_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="118"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="157"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="188"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU367016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="231" mass="26054" checksum="C5EE2D410439B159" modified="2010-01-19" version="1">MLDSFLSIFTALWHQDFVALKNPESILMIYFCVTFVIWLESAFLPAAPLPCDSIVILSGTLGAMGIIDYKVIFILLVAASATGSWLAYLQGRWLDHLPKVQRWVKMVPPHRMQTVDSLLMRHGLVALFVARFIPVVRPLLPLMMGLRVKSKTHFYRFTWVSATAWVGLLTGFGYSLKFLPEKVAHVVTIILMVAPLITLAVAVCSVLAGWLLRRKKRNAEMNQTQVEQSIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2M8</accession>
    <name>D0Z2M8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">4-alpha-glucanotransferase</fullName>
            <ecNumber evidence="3 7">2.4.1.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5 7">Amylomaltase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6 7">Disproportionating enzyme</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_000679</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>Transfers a segment of a (1-&gt;4)-alpha-D-glucan to a new position in an acceptor, which may be glucose or a (1-&gt;4)-alpha-D-glucan.</text>
            <dbReference type="EC" id="2.4.1.25"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the disproportionating enzyme family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.25" evidence="3 7"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305038.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000679"/>
    <dbReference type="EnsemblBacteria" id="EEZ39659">
        <property type="protein sequence ID" value="EEZ39659"/>
        <property type="gene ID" value="VDA_000679"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="814704at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004134">
        <property type="term" value="F:4-alpha-glucanotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102500">
        <property type="term" value="F:beta-maltose 4-alpha-glucanotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003385">
        <property type="entry name" value="Glyco_hydro_77"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32438">
        <property type="entry name" value="PTHR32438"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02446">
        <property type="entry name" value="Glyco_hydro_77"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00217">
        <property type="entry name" value="malQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7 8" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00031423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ39659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="726" mass="81857" checksum="C2FFB563527343CD" modified="2010-01-19" version="1">MLENSVLKHVAHMAGITDKYISAWGDEATVEDETLSRLLAALGYDVRNDEALLESARKKNRTEVLAPVKVIRAGEPMQVELHLGASARVSDFSWRLETEQGEVFEGWLQSQLVADERDEGQPLVFALPNDLAWGYHKLTVSRKRRKSPYEMTLIVTPTACYKQTALLNNKKLWGTSVQLYSVRTQHNWGIGDFGDLKQLVADIAKNGGDFVGLNPIHSLFPANPEGASPYSPSSRRWLNVIYIDVSSVCEFAQSDAAQQLVGSHEFQQRLAEARQSNWVNYSEVACLKMAALRLLFDTFVTRHLEKNTERAKQFLNFVEQGGESLLHQAAFDALHALLKSQDDTMWGWPVFPESYRHFDNQAVQTFIQENQHEVQLYMYLQWLADCQLAEVQELAEEKGMVMGLYRDLAVGVCDSGAETWAQHGELCLDVSVGAPPDILGPLGQNWGLPPLNPEVLVERAYQPYIDLLRANMRHCGALRIDHVLGLLRLWWIPKGESAKAGAYMYYPVEDLLAILALESHRHQCTVIGEDLGTVPDEIIDKLATAGVHSYKVFFFETAEDGGYFSPRHYPDQSMAALCTHDMPTLRGFWHCDDLKMGSELGLYPDQDALNGLFDSRAESKQRILDSLDWHGYLSQNIGRNAAYVPMDSKLSEGMQLHLAAGASALLSLQLEDWLEMDKPVNIPGTVDEYPNWRRKLSTTLDDLFTRQDIIDLTRRLTEARQQASEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2T6</accession>
    <name>D0Z2T6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000737</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305207.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000737"/>
    <dbReference type="EnsemblBacteria" id="EEZ39717">
        <property type="protein sequence ID" value="EEZ39717"/>
        <property type="gene ID" value="VDA_000737"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502Z95A">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1856931at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039498">
        <property type="entry name" value="NTP_transf_5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14907">
        <property type="entry name" value="NTP_transf_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="366" mass="42584" checksum="B8EDA6846ED16D98" modified="2010-01-19" version="1">MTVPPVILIDILKRPSLLTSLSEQHQSAILTEARHVNLLGQLQYLCHQHDVFDDLFLHSQQTLLSGQQAHLAQCKQLNDYHNVLTQALTQATSTWSYINQAGIQFSQQQSRLGYLRQTTEILVSHNAIHHIEKCLLTHGWRPKLISDYDEKSRIRYTNALSPFIHQESNLELVVHYQLLPKRFRYSSDDTFTRKLIYPDSCYPASIFDPISTIYHLAINLFFINDSKFGLRDIFTLYSLLNENSLQEGFWGELLTFQNKVGKDSSLFLALHFCHVLFDLAIPDFVSQYYHQQFKVSVTLNSLETSYIDLFSYAFPPYQDDDYKLAARLLRIRGCIKQMPLYLLLPHIIKRGIWNCLPHESEEELIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2V5</accession>
    <name>D0Z2V5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">UPF0056 membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_000756</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the UPF0056 (MarC) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305260.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39736">
        <property type="protein sequence ID" value="EEZ39736"/>
        <property type="gene ID" value="VDA_000756"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2095">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1323133at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002771">
        <property type="entry name" value="Multi_antbiot-R_MarC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33508">
        <property type="entry name" value="PTHR33508"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01914">
        <property type="entry name" value="MarC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00427">
        <property type="entry name" value="TIGR00427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="68"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="145"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="180"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ39736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="216" mass="22654" checksum="69F1F74DD8C0415D" modified="2010-01-19" version="1">MHDIGTMAVSVFMGFFAMMNPFANTAVFVGMTGGLPAKQVRAIALKALVTAFAIIAAFSFLGKGIFEVFGITLPALRMAGGVLVFLVGYHMLQGNSSSMHSSQNASQDSDNNSDQDIAISPLALPLLAGPGTIATAMNYSAAGNMLHIIITISAFAALCLITYVYFIYGPKLIEKVGQSGISIITRLMGLILTVIGMQMGIQGVHDAIVLFNSTPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2Y6</accession>
    <name>D0Z2Y6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sodium-dependent transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000787</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305347.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000787"/>
    <dbReference type="EnsemblBacteria" id="EEZ39767">
        <property type="protein sequence ID" value="EEZ39767"/>
        <property type="gene ID" value="VDA_000787"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0385">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1493959at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002657">
        <property type="entry name" value="BilAc:Na_symport/Acr3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004710">
        <property type="entry name" value="Bilac:Na_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10361">
        <property type="entry name" value="PTHR10361"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01758">
        <property type="entry name" value="SBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="41"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="68"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="99"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="173"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="197"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="232"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="259"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="286" mass="30883" checksum="02400FEDEB135FAD" modified="2010-01-19" version="1">MQHIVTQVLLPITLAIVMLGMGLGLKRADFSRVITQPKSSIIGLCLQIFMLPTLALVIIQLLPLSSTAAAGLFLVSLCPGGATSNLFSLIAKGDVALSITLTAVISLLSPFLLPLIFITYLDIHGSQLEQFQLPIDLAIKQLIAVTVLPISLGMIITKWLPKQSQLIQPMVKKLSTIAMLLIILALLITNQKIFDRFISIEGIAVLLLSSCSLFLAYFIAGKIKVSQQAQRTIAIEVGVQNAGTAMMVALSIMHQPQLAAVPLMYGLLMNIPACLFVAWVSRKSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2Z0</accession>
    <name>D0Z2Z0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ExbD2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_000791</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ExbD/TolR family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000791"/>
    <dbReference type="EnsemblBacteria" id="EEZ39771">
        <property type="protein sequence ID" value="EEZ39771"/>
        <property type="gene ID" value="VDA_000791"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0848">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003400">
        <property type="entry name" value="ExbD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30558">
        <property type="entry name" value="PTHR30558"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ39771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="45" mass="4667" checksum="393F60360FBE141A" modified="2010-01-19" version="1">MLVDQPDASLVIQADEHAYNGTVVKVMDAAKGAGVKNIALAAENK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z398</accession>
    <name>D0Z398_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000899</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305668.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39879">
        <property type="protein sequence ID" value="EEZ39879"/>
        <property type="gene ID" value="VDA_000899"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG50315TZ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1831467at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="289" mass="32054" checksum="5770C5DF7C958C52" modified="2010-01-19" version="1">MNDNAIKKVFKCSYDMPSTKEHTIDAELLGNTILSLAKVIKTSNRLVNGEDANIKLNVKAHEEGSFVVEFVAWVNQNGLDILDILGITMGTPIIGGTVFGALEQIKDNKIIAKIKKKDQQYQLQLSNGSFVECTEQVADIVTDPIVRSDLAKVINNPLSGDKDSKFILKDENNQPILSVDGESAQSFQSIPRTTLEEVINDVKQVTIHFSQVNFDGPTGWKCALPSGEIVSVRMRDTAFRDRINKGYEEFSKTKPSLVKLLTVEKKKADGSVTISYYIEEMIRQLGKNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3D9</accession>
    <name>D0Z3D9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000940</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39920">
        <property type="protein sequence ID" value="EEZ39920"/>
        <property type="gene ID" value="VDA_000940"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031PY1">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="54" mass="6089" checksum="1CA68E0DE77E9D1A" modified="2010-01-19" version="1">MQQNKARVISNWKPTNQREAAAMKELLMQEMGVTERVHPGGTGKLAQNNGRLIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3F1</accession>
    <name>D0Z3F1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000952</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39932">
        <property type="protein sequence ID" value="EEZ39932"/>
        <property type="gene ID" value="VDA_000952"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="38" mass="4071" checksum="BD5C60C129A6FB83" modified="2010-01-19" version="1">MRVNMMGPIVLISDLLAKIKGESDPDSDESVELVPATV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3I5</accession>
    <name>D0Z3I5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Carbamoyltransferase HypF</fullName>
            <ecNumber evidence="8">6.2.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">VDA_000986</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + C-terminal L-cysteinyl-[HypE protein] + carbamoyl phosphate + H2O = AMP + C-terminal S-carboxamide-L-cysteinyl-[HypE protein] + diphosphate + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:55636"/>
            <dbReference type="Rhea" id="RHEA-COMP:14247"/>
            <dbReference type="Rhea" id="RHEA-COMP:14392"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="ChEBI" id="CHEBI:76913"/>
            <dbReference type="ChEBI" id="CHEBI:139126"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>an acyl phosphate + H2O = a carboxylate + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14965"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29067"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:59918"/>
            <dbReference type="EC" id="3.6.1.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Protein modification; [NiFe] hydrogenase maturation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the carbamoyltransferase HypF family.</text>
    </comment>
    <dbReference type="EC" id="6.2.-.-" evidence="8"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305913.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000986"/>
    <dbReference type="EnsemblBacteria" id="EEZ39966">
        <property type="protein sequence ID" value="EEZ39966"/>
        <property type="gene ID" value="VDA_000986"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0068">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="48295at2"/>
    <dbReference type="UniPathway" id="UPA00335"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003998">
        <property type="term" value="F:acylphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016743">
        <property type="term" value="F:carboxyl- or carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046944">
        <property type="term" value="P:protein carbamoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001792">
        <property type="entry name" value="Acylphosphatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036046">
        <property type="entry name" value="Acylphosphatase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017968">
        <property type="entry name" value="Acylphosphatase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004421">
        <property type="entry name" value="Carbamoyltransferase_HypF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017945">
        <property type="entry name" value="DHBP_synth_RibB-like_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041440">
        <property type="entry name" value="HypF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006070">
        <property type="entry name" value="YrdC-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011125">
        <property type="entry name" value="Znf_HypF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00708">
        <property type="entry name" value="Acylphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17788">
        <property type="entry name" value="HypF_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01300">
        <property type="entry name" value="Sua5_yciO_yrdC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07503">
        <property type="entry name" value="zf-HYPF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006256">
        <property type="entry name" value="CMPcnvr_hdrg_mat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54975">
        <property type="entry name" value="SSF54975"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55821">
        <property type="entry name" value="SSF55821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00143">
        <property type="entry name" value="hypF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00150">
        <property type="entry name" value="ACYLPHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51160">
        <property type="entry name" value="ACYLPHOSPHATASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51163">
        <property type="entry name" value="YRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Acylphosphatase-like" evidence="10">
        <location>
            <begin position="4"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="YrdC-like" evidence="11">
        <location>
            <begin position="206"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="19"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR006256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ39966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="786" mass="88032" checksum="E0EAD14E89B7A83C" modified="2010-01-19" version="1">MISHQFIHVTGIVQGVGFRPFVYQLALEYQLLGWVINDSEGVKIDAQGTVEQLTQFVEQLERQAPPLSRIDHIEITVLPSWNKAQCPTEFAIQESCERESTSVSISPDQGVCQACLADLEDPRSRYYHYPFTNCTHCGPRYSIIKALPYDRCHTSMANFQFCQPCEQAYKNPLDRRYHAQPISCEHCGPWVSWHQHSTAETDSVGEQAIESLAKQILAGGVVALKGLGGFHLICDASDNVAVERLRQYKHRPKKPLAIMVQSLSDARVFAQGCDKEWQTLDEQKRPIVLLKKNRESILAPNLAPNVPYLGIMLPYTPLHFLLFAKLAELKPHTPHALVMTSANRSGLPIATCFEEVIAQFGTELDGILNHNRPILHACDDSLVHVIDDKVHVLRMARGYAPFSRFADTHNQATLAMGAQQKASIGLALPQQWMLSPFIGDLDNVDNEMRYQEAIKTFTSLYHVSPQRIVCDYHPGYRSTELAQRMVTDDSSISLTQIQHHHAHVLAVMAEHNLTEQVLGFTFDGTGYGEDETVWGGEVLLADTHNFKRVASLRSFRLLGGEQAIKEPARLLLAILLEFMSIEQVCSLQEKLFPQWTSATLENLYQLWQSGSRSPYTSSMGRLIDAMAYLLGVLERVSYEGEAGLLLEQAALNSQYELLYPLPELSLVSLNAQSDFTVIDWQPCFESVLSCRLSVAFNQMLQNRLAHAFLRNIAQSIFTLAENYPALPLVLSGGVFQNRIILQSAYTLASARDSALQQKQPIYSGELIPVNDGGIAAGQLWYAIHNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3M9</accession>
    <name>D0Z3M9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001030"/>
    <dbReference type="EnsemblBacteria" id="EEZ40010">
        <property type="protein sequence ID" value="EEZ40010"/>
        <property type="gene ID" value="VDA_001030"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3677">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="205" mass="23983" checksum="111C774B6300C15E" modified="2010-01-19" version="1">MEDPLTNQAKINYPTKGCLIRPQYTAYAHYLHLAQQLKENNEQLSLFMPQETLLRSACISVFLERVKDKSFHPLYVVEDADWLDQEVSERIDIVLLGWWRDRWAFTRHNETSKGISHLGGEKDNEKRWLEIASHRAISEYQSRFHDQFSQLVNEPRRKLRPGGLMPLLDIYRAWHNLCRQDRSGLTPAQKIGLTSAPLTLEQLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3N6</accession>
    <name>D0Z3N6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001037</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306048.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001037"/>
    <dbReference type="EnsemblBacteria" id="EEZ40017">
        <property type="protein sequence ID" value="EEZ40017"/>
        <property type="gene ID" value="VDA_001037"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1289">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1512691at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006726">
        <property type="entry name" value="PHBA_efflux_AaeB/fusaric-R"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04632">
        <property type="entry name" value="FUSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="378"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="404"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="428"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="453"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="507"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="729" mass="83147" checksum="67CCB99397DD7A6B" modified="2010-01-19" version="1">MISKRWIMPLKVASALTLAIVIALAFGWNKPYWAAFAVIVMAATETNGHSLKKGRLRLLGTCAGVVIAFILVSLLGQQPLAFLVVYSIIIAICIYQQSNPKNGYAWTMGLMVSCVIIVMGKMTSEQTFTIAALRLQETILGVLCFSFVFSIFSPASSRITLLNTLKNNAETKQDKIEQAICSLQANNTLSKNVSWGDGLKYLARIDDLLQAAKSDSYQVSSEFTIWDSIREQQNQWILLSGHLSEAINLINTPFTQEQKEDLIEILTQLKTRYSNSITLLEYTVEHPHSTMDDLRQYLNNTTAKSSYTLTLESLLDNRNSQHGALRMLAENLLKMDTLQEQMYQNLIQAIINDKPSKAHPKKPTKSSVLTLTFDSERLINVLKILIIFWVSVALWVYVPMQGGAMIVMLSLIFGSVALSLPFVSPRYILLHMICWAALALLQYTFILPHLSHLWQLGLFYFINVFSLWFYFNQPQQIFHRLLGCQTLMLMTTSAIQLTPSYNIETSLLTITLLSIALLIIFWIYNGIFSSQPEFVFLRQLTQFRIRLYFKINKLLRKKTHSLISLELSTPVQAVSLAEMASTKINWSTYNDLDKDKVENVLNLAYRACFHYRSFEDNYNNWREKQYSEGINRLIVESLTELANIMRTSMIHEKISTTHTATLSALQEYLISYRHNESLSALNAVFTVDEINKNYQLITSLLLFIQSLKEVSTQISTQQLYQLKLSPFSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3N8</accession>
    <name>D0Z3N8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Inosine-uridine preferring nucleoside hydrolase</fullName>
            <ecNumber evidence="4">3.2.2.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001039</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.2.2.1" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306054.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001039"/>
    <dbReference type="EnsemblBacteria" id="EEZ40019">
        <property type="protein sequence ID" value="EEZ40019"/>
        <property type="gene ID" value="VDA_001039"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1957">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1763387at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008477">
        <property type="term" value="F:purine nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901564">
        <property type="term" value="P:organonitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.245.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001910">
        <property type="entry name" value="Inosine/uridine_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023186">
        <property type="entry name" value="IUNH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036452">
        <property type="entry name" value="Ribo_hydro-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12304">
        <property type="entry name" value="PTHR12304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01156">
        <property type="entry name" value="IU_nuc_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53590">
        <property type="entry name" value="SSF53590"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IU_nuc_hydro" evidence="3">
        <location>
            <begin position="5"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="325" mass="35968" checksum="E63BDDFD0B799935" modified="2010-01-19" version="1">MTKKIILDTDPGIDDAMAILFAEAHPDIDLMAITTVFGNATIENGTHNALYLKQRFQMKADIAKGARQPLMRPPVGPTEIVHGKTGLGDFHAPELIDKAIDLRPAYQYIIESIRANPQEITLVAVGPLTNLAMAIQAAPDIASLVKEVVIMGGAFGVNDHRGNVTPYAEANIHDDPHAADIVFSASWPVKIIGLDVTEESFFSGQYLDQLRDHAGSVGQFIWDISRYYLRFYSNKVGLDGCHVHDPSAIAYVINPDLFSFRSGAVRVVCEGPAEGMTIQKFDDKFYPIDEWSIRPSQQVGVDVDEKQLLALYQQTIVNYSYQFEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3P4</accession>
    <name>D0Z3P4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hypothetical ABC transporter substrate binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001045</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306069.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001045"/>
    <dbReference type="EnsemblBacteria" id="EEZ40025">
        <property type="protein sequence ID" value="EEZ40025"/>
        <property type="gene ID" value="VDA_001045"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2113">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="770506at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007210">
        <property type="entry name" value="ABC_Gly_betaine_transp_sub-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04069">
        <property type="entry name" value="OpuAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018818" evidence="2">
        <location>
            <begin position="22"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="OpuAC" evidence="3">
        <location>
            <begin position="26"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="333" mass="36646" checksum="5FB9DEE9448E8208" modified="2010-01-19" version="1">MRKTLAVLLLSSLGFSLQAQANECGKVTIADMNWNSASFLANLDQFVLNNAFGCSAELVPGDTMPTGTSMIEKGEPDIAPEFWSNSMKAALDRGVEDKRLRLIGGPFADGGVEGFWVPAYMVEKDPSLATIAGIKKHAKLFAHPEDQSKSAFYTCPSGWNCQISAGNIFRALKLKQAGFELVDPGSGAGLAGSIAKAYERQQPWFGYYWAPTAVLGKYKMVKVDFDSGTDPEYFKSCLTQDTCLDPKPSMYPTSQVDTVITESFANKAGDALKYLQQRALTNEQMNELLAWMEENQADGEIAMEHFLTDYESTWTTWFTPAQATKLKQALKNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3R2</accession>
    <name>D0Z3R2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">GALNS arylsulfatase regulator (Fe-S oxidoreductase)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_001063</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001063"/>
    <dbReference type="EnsemblBacteria" id="EEZ40043">
        <property type="protein sequence ID" value="EEZ40043"/>
        <property type="gene ID" value="VDA_001063"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0641">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1172757at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023885">
        <property type="entry name" value="4Fe4S-binding_SPASM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034491">
        <property type="entry name" value="Anaerob_Ser_sulfatase-maturase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023867">
        <property type="entry name" value="Sulphatase_maturase_rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43273">
        <property type="entry name" value="PTHR43273"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13186">
        <property type="entry name" value="SPASM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00285">
        <property type="entry name" value="anaerobic_Ser-type_sulfatase-m"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01384">
        <property type="entry name" value="thioether_bond_formation_requi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04085">
        <property type="entry name" value="rSAM_more_4Fe4S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="7">
        <location>
            <begin position="2"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ40043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="417" mass="47210" checksum="BD3F40E884F4AF00" modified="2010-01-19" version="1">MATARFHMMAKPTSYRCNLKCEYCFYLEKEEILGDSQSSECVSATSKQPDVMPNPVLKRYVRDYIASQDADQIDFSWQGGEPTLAGLDFYRQVVKYQRQYANGKTITNSFQTNAVAINKQWAQFFAEHQFLIGVSIDGTPDIHDKYRISVNGKPTFERVKRAIELLLEYQVEFNVLTVINDQNWDKGAQTYQFLKSLGARHLQFIPIVEVEGSATTSTRHYAPEKNNNVTHFSVPAYGYGQFMTEVFEEWLKEDVGTVYVRMFDSILATWLGYPASVCVQSKNCGQAMVIEANGDVYSCDHYVYLANRLGNVAELSLTKMATSKQQQRFGNAKSTKLTDQCQSCEVHGLCYGGCPKHRIVHQEGQKHKQNYLCPSYQKIFRHTAPAMHLMSQAIRQGGTAADALPMIAHARGQHAFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3W2</accession>
    <name>D0Z3W2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative phosphatase YieH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001115</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306263.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40093">
        <property type="protein sequence ID" value="EEZ40093"/>
        <property type="gene ID" value="VDA_001115"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0637">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1167152at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00413">
        <property type="entry name" value="HADHALOGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="229" mass="25452" checksum="F035CB6D82A5EEAC" modified="2010-01-19" version="1">MGNKSNIQCIIFDCEGTLVDSERLVCQAIVNAFAIFNVPLQLKDCVQHFEGGKITEQLAKVQHRSGTSIDIDKLEPIYRQQYALLSETHLQPIPGVVDLLTRLKARNIELCVISNSSKVKLKAILSQTQLSHFFGNNLFCGDDVGNWKPAPDILLYSAMYLGFSKDECLYVDDTVQGVQTGIAAGIRTYQYQDIIHSYRAVSDQAPVIRSSIELLSIIDSSFTSQPHIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3X4</accession>
    <name>D0Z3X4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative xanthine/uracil permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_001127</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306287.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001127"/>
    <dbReference type="EnsemblBacteria" id="EEZ40105">
        <property type="protein sequence ID" value="EEZ40105"/>
        <property type="gene ID" value="VDA_001127"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2252">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="558559at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015205">
        <property type="term" value="F:nucleobase transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904823">
        <property type="term" value="P:purine nucleobase transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045018">
        <property type="entry name" value="Azg-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006043">
        <property type="entry name" value="NCS2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43337">
        <property type="entry name" value="PTHR43337"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00860">
        <property type="entry name" value="Xan_ur_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="34"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="88"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="112"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="146"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="176"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="207"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="260"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="303"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="337"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="361"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="393"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="432"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="453" mass="46557" checksum="5FEBB96D816FA4B7" modified="2010-01-19" version="1">MSDNRSIASHATGHTGLDRFFQISERGSSVRQEVVAGLTTFLAMVYSVIVVPSMLGAAGFNQGAVFIATCLVAAFGSLLMGLWANLPMAIGCAISLTAFTAFSLVLGQGISIPVALGAVFLMGLIFTAITVTGVRKWILSNMPFGIAHGTGIGIGLFLLLIAANGVGLVVKNPHEGLPVAMGDFTSLPVLMSLIGLAAIFGLEKRRVPGGILLVIIAISVFGLIFDPKVTFHGFFAMPTFGSEGESLLGTMDIMGALNPVVLPSVLALVMTAIFDATGTIRAVAGQANLLNERGHIISGGKALTADSVSSIFAGFVGGAPAAVYIESAAGTAAGGKTGLTATVVGALFLLMLFLSPLSYLVPAYATAPALMYVGLLMLSNVSKLNMDDLVDGLSGLLCAVFIVLTSNIVTGIMLGFAALVIGRVISGEWRRLNIGTVLIAIVLVAFYAGGWAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3Y4</accession>
    <name>D0Z3Y4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chromosome (Plasmid) partitioning protein ParB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001137</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ParB family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306314.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001137"/>
    <dbReference type="EnsemblBacteria" id="EEZ40115">
        <property type="protein sequence ID" value="EEZ40115"/>
        <property type="gene ID" value="VDA_001137"/>
    </dbReference>
    <dbReference type="GeneID" id="57343395"/>
    <dbReference type="eggNOG" id="COG1475">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="653368at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004437">
        <property type="entry name" value="ParB/RepB/Spo0J"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003115">
        <property type="entry name" value="ParB/Sulfiredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036086">
        <property type="entry name" value="ParB/Sulfiredoxin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02195">
        <property type="entry name" value="ParBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00470">
        <property type="entry name" value="ParB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110849">
        <property type="entry name" value="SSF110849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00180">
        <property type="entry name" value="parB_part"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ParB" evidence="2">
        <location>
            <begin position="58"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="324" mass="36239" checksum="0B0DFEB8C3DE1249" modified="2010-01-19" version="1">MAIKTKDLNARLFGKADKRRATTPIEAQTAAKDKAAVIELAVAGEETVAFELVKIPAAEVATKTVVFTENAREQAFLNEHALADILSTLKDRGQQYPAVGRWMDDGRIEVLDGSRRRMSCILAQKDFLIYVANGINTEHAKFLSDVANAHKPLSLYERGKEMQALLNNGKVADQKELAKYCQCSEALVSGALKAASLPMELLMAYPSVGELGRPTIVKLHRIFFGLDDNKQHELIDQLSQTNKPLWKQINAQGISRITREVTMKLEEMGESLKPQQPIEKPKAQELVKGKVSYTRDGDKLQLKLKKMSDRQVSDILQYLTEYLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-08-12" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z447</accession>
    <name>D0Z447_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Urease accessory protein UreF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ureF</name>
        <name evidence="4" type="ORF">VDA_000303</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the UreF family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303989.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000303"/>
    <dbReference type="EnsemblBacteria" id="EEZ39285">
        <property type="protein sequence ID" value="EEZ39285"/>
        <property type="gene ID" value="VDA_000303"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0830">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1942614at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01385">
        <property type="entry name" value="UreF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002639">
        <property type="entry name" value="UreF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038277">
        <property type="entry name" value="UreF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01730">
        <property type="entry name" value="UreF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009467">
        <property type="entry name" value="Ureas_acces_UreF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 3" id="KW-0996">Nickel insertion</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="221" mass="24957" checksum="882A5EE8D69009F3" modified="2010-01-19" version="1">MLADLRLYQLISPSLPVGSFTYSQGLEWAIECGWISDPQTLKQWLTQQLLDSIATLELPVLYKMIDALTKGKTQQAQEWSQLIVASRETKELRAEERQRGYAFAQLLPKLGIELSEEELAMVKQTQIAAFSLAGIHWKIPNHQLAKGYLWAWLENAVMAGVKLVPLGQTAGQQLIFELAEMIPIALEKSLTWPDNNIGSFTPAQVIASCRHETQYTRLFRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z456</accession>
    <name>D0Z456_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative dipeptide ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_000312</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000312"/>
    <dbReference type="EnsemblBacteria" id="EEZ39294">
        <property type="protein sequence ID" value="EEZ39294"/>
        <property type="gene ID" value="VDA_000312"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1124">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1303270at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="198" mass="22474" checksum="8AEB00E6015A2B24" modified="2010-01-19" version="1">MTESIYLQNGVIKLDSREIILPDLVLNRGDIIGICGESGCGKSTLASVLAGYQKLDAGELNVPLHLKGQANPVQWIEQHPEKTFDPHWTIAQSLKEAYRKQDTISFLVDYQIHAAWLERYPRQLSGGELQRINILRAMVPSTQFLICDEITAQLDSITQQQLWQTVMQEVKARNIGLLIISHQEALLRKLCDRIIVWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z478</accession>
    <name>D0Z478_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="13">PTS system fructose-specific IIC component</fullName>
            <ecNumber evidence="13">2.7.1.69</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">VDA_000334</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.7.1.69" evidence="13"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000334"/>
    <dbReference type="EnsemblBacteria" id="EEZ39316">
        <property type="protein sequence ID" value="EEZ39316"/>
        <property type="gene ID" value="VDA_000334"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1299">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103111">
        <property type="term" value="F:D-glucosamine PTS permease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008982">
        <property type="term" value="F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013014">
        <property type="entry name" value="PTS_EIIC_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006327">
        <property type="entry name" value="PTS_IIC_fruc"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01427">
        <property type="entry name" value="PTS_IIC_fructo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51104">
        <property type="entry name" value="PTS_EIIC_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0598">Phosphotransferase system</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="13" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="69"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="112"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="150"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="189"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="250"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="289"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="PTS EIIC type-2" evidence="12">
        <location>
            <begin position="1"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="315"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ39316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="334" mass="34603" checksum="8DA73B600E963D1B" modified="2010-01-19" version="1">MLPFVVAGGVLLALSVMLGGKGAVPEGVFLEGLWDMGIAGFTLFVPVLGGYIAYSIADRPALAPGMIGAYLANQVQAGFLGAIVVGFIAGYVVLQLKRIPLSNKLKAISTYFILPIGGTFIVSALVIWVIGAPIAAAMEAMNGWLQGMAGASKAFLGVILGGMTAFDMGGPINKVATLFAQTQVGTQPWLMGGVGVAICVPPLGMFLATLLSPKRYTDEEREAGKAAGIMGCIGITEGAIPFAAADPMRVIPSIVVGGMVGNVVAFMFGVLNHAPWGGLIVLPVVDGRLYYILAIVAGSVATALMVNALKKPIEQRQDSVQQDSDDDSLELTFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4C9</accession>
    <name>D0Z4C9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000385</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304218.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000385"/>
    <dbReference type="EnsemblBacteria" id="EEZ39367">
        <property type="protein sequence ID" value="EEZ39367"/>
        <property type="gene ID" value="VDA_000385"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4129">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="813147at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022604">
        <property type="entry name" value="DUF2955"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11168">
        <property type="entry name" value="DUF2955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="177"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="225"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="249"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="339" mass="38417" checksum="D8E53AB144FAA10E" modified="2010-01-19" version="1">MKWFNNIINNKDALRVALTVTVCMMLGKLLHLNSPVYLALYPAIVMTKVKDYRWRGLFKSLFPTLISATLAIITTEIFRDHPFIIWTISILLFDTLRKKADTPPKVGALFMPTINWILNIVFAQHTTMNMPERIHEIFIAMVITAVVTKGMLWLLPKAKGTKPPQFKPYPITFEHRLVSISLMGIGLGFLMIVNLVSAAFCMVPVIAAATQFNRQNYLKVIKGRFWTQVGGCAIAAIFSILMTGHQNMFFIYGIALFVLLYIIADQMHNDDTPAQRDTHADILLATVLPLQLYMNSSELGLSSTFLRGWELAVTLGILWLFHRLTQTREHNGQTHNAHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4F1</accession>
    <name>D0Z4F1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">PMT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_000407</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304284.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000407"/>
    <dbReference type="EnsemblBacteria" id="EEZ39389">
        <property type="protein sequence ID" value="EEZ39389"/>
        <property type="gene ID" value="VDA_000407"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1807">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="854536at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000030">
        <property type="term" value="F:mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006493">
        <property type="term" value="P:protein O-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003342">
        <property type="entry name" value="Glyco_trans_39/83"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02366">
        <property type="entry name" value="PMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="96"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="125"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="170"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="215"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="276"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="316"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="362"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="domain" description="PMT" evidence="8">
        <location>
            <begin position="24"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ39389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="481" mass="54298" checksum="EC42814056CC29E9" modified="2010-01-19" version="1">MRIFNKLTKQTSLAHIAIITVISTFIIRFVTLSMYPLMDTTEARYGEMARIMAETGNWITPMFDYNVPFWGKPPLFSWLSAASIKLLGNSEFAVRLPHLLVGILITIITYLFAKKVQKNNTVALLSAAILATSTAFIVISGAVMTDTALTFAITLSMVSFWRNWQQPSLFFGLLFFVGLAIGMLAKGPLTLVLVGMSIILWSLSDGRWRLLYAKLPWGYGLVTFLVLTLPWYLLAEWKTPGFLHYFIIGEHFMRFVVSGWKGDLYGTAHEELRGTIWLLALLATLPWSPLFIWQLIKRLKAGGDSKSSSDGYLSFLWCWMLAPLFLFTFAGNILTSYVMPSIPAFALLLSRYQSEQPLNKKVYTIGFITPILLFITAIVLGSGVTGKTADNRLLTIWKQQPEHNQSALVYLGKRPFSAQYYSDGKAVRSEAKPDQLLADLNKSTFIVLSNTQDNLRDIQQYPNCQQRGKTSERILYYCSIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4J6</accession>
    <name>D0Z4J6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000454</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0438 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000454"/>
    <dbReference type="EnsemblBacteria" id="EEZ39434">
        <property type="protein sequence ID" value="EEZ39434"/>
        <property type="gene ID" value="VDA_000454"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3085">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007335">
        <property type="entry name" value="DUF413"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04219">
        <property type="entry name" value="DUF413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="70" mass="7969" checksum="03FAAB44BE04D470" modified="2010-01-19" version="1">MPVDESELQFVAEVKGQQEAISDFGKCWLKYLNQTNHKVRSYTLCVSQRSKGSYGEDDDDGSDVDNDIDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4Q0</accession>
    <name>D0Z4Q0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative LuxZ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_000508</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000508"/>
    <dbReference type="EnsemblBacteria" id="EEZ39488">
        <property type="protein sequence ID" value="EEZ39488"/>
        <property type="gene ID" value="VDA_000508"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1802">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011711">
        <property type="entry name" value="GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008920">
        <property type="entry name" value="TF_FadR/GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07729">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48008">
        <property type="entry name" value="SSF48008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="4">
        <location>
            <begin position="10"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="232" mass="26853" checksum="86D9159DE19DFBAB" modified="2010-01-19" version="1">MASLEKDNFSTISDRVMHQIRNDILNGEFEAGQKLILSDLKQRYNVGGSPLREAMVQLSWQKYVILKPQKGFWVADVSLDELKSIIKARLAIGNMALCEAMEHGDEKWELNILTTYHKLSRLDPNSPDFTLTLWERRHKDFHMALISCKGAEFVMGLMSTIYDQQERYRHFLLGSKFTHETQYHDNGEHEAMMKAVLDRNLDLACELVRQHTEKLYQVIKQVGSLQALNPTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4U7</accession>
    <name>D0Z4U7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chromosome (Plasmid) partitioning protein ParB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306530.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000180"/>
    <dbReference type="EnsemblBacteria" id="EEZ39164">
        <property type="protein sequence ID" value="EEZ39164"/>
        <property type="gene ID" value="VDA_000180"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1475">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014884">
        <property type="entry name" value="ParB_fam_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08775">
        <property type="entry name" value="ParB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ParB" evidence="1">
        <location>
            <begin position="234"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="349" mass="39270" checksum="B4090296A69240D9" modified="2010-01-19" version="1">MAKKKAVMGLTDNQPGAYESKQNLARANLESLPEQLRRDLEITGTGLHEYLANTFGIETASNEVEWILESGKKETFVEVKLSYEQVKNETYVDFQVNGRYQDLLNQNNLSDLSTLDFQQFYPAIGCRVENIINILDGSRRRAYFLLKKGGIKYFTVLLAQGNISQSDAKALAKSLQSAKEHNLYEIGKRCELYKDAGLKSQEEIANALGISRTKVTRAMQAASIGRDLYHLFNDINDLTVKDYAVLTKVEKALSSRKDRTELLSTVESSPDSDIKEIIDALLHLIIPPKKSAPTISVTSLVEFDDKNRHARKKVKGRNVNYEFGRLSASELEHIDKAIQSALDELFSNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4V5</accession>
    <name>D0Z4V5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Type 3 secretion system secretin</fullName>
            <shortName evidence="7">T3SS secretin</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">sctC</name>
        <name evidence="10" type="ORF">VDA_000188</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the type III secretion system (T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells. Forms a ring-shaped multimeric structure with an apparent central pore in the outer membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">The core secretion machinery of the T3SS is composed of approximately 20 different proteins, including cytoplasmic components, a base, an export apparatus and a needle. This subunit is part of the base, which anchors the injectisome in the bacterial cell envelope. Forms a stable homooligomeric complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 7 8">Cell outer membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the bacterial secretin family. T3SS SctC subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306553.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000188"/>
    <dbReference type="EnsemblBacteria" id="EEZ39172">
        <property type="protein sequence ID" value="EEZ39172"/>
        <property type="gene ID" value="VDA_000188"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1450">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="881521at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030257">
        <property type="term" value="C:type III protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030254">
        <property type="term" value="P:protein secretion by the type III secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.120">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02219">
        <property type="entry name" value="Type_III_secretin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005644">
        <property type="entry name" value="NolW-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038591">
        <property type="entry name" value="NolW-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004846">
        <property type="entry name" value="T2SS/T3SS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004845">
        <property type="entry name" value="T2SS_GspD_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003522">
        <property type="entry name" value="T3SS_OM_pore_YscC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00263">
        <property type="entry name" value="Secretin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03958">
        <property type="entry name" value="Secretin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01337">
        <property type="entry name" value="TYPE3OMGPROT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02516">
        <property type="entry name" value="type_III_yscC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00875">
        <property type="entry name" value="T2SP_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0732">Signal</keyword>
    <keyword evidence="5 7" id="KW-0811">Translocation</keyword>
    <keyword evidence="7 8" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5026397250" description="Type 3 secretion system secretin" evidence="7">
        <location>
            <begin position="31"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="domain" description="Secretin_N" evidence="9">
        <location>
            <begin position="188"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ39172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="624" mass="68912" checksum="72D8028C43D589E0" modified="2010-01-19" version="1" precursor="true">MLAVLKKQLRRLVWSVAYTLSLLAALSLHASELDWPDQPFRYYANNDSLKELLNNFGANYRVSVSVSDKVNDRVSGRFTPEDPAEFLDYLAQLYNLMWYFDGAVLHVYKATETRSRLLQLELLTANELRSTLISTGIWDSRYGWRAAENKGLVYLAGPPRYVDLVVQTAEALESRLVQKSNSTDELFVEIIPLKYASATDREITYRDQVVTVPGIASVLSRVLSGVQTQIKATKESEETDINTAATTTKNVSVHGGASVEAEPGLNAIIVRDTQARLPLYRKLVAQLDQPQSRIEVALSIVDISANDLSQLGVDWRAGIAVGNNSILDIKTTGDVDGGDVTLGSGQTFKSLLDATNLNYLLAQIRLLESQGSAQVVSRPTLLTQENVEAVLNNSSTFYVKLIGREIAALEKVTYGTLLRIVPRIVGDRFVERPEINLSLHLEDGAQIPDGGVDNVPSIRKTEISTLATVKQGQSLLIGGVYRDEVSHQLRKVPLLGDIPYLGALFRNTTDTTRRTVRMFIIEPRIVVDGIGDNVLIGSNEYDLRPKLGTLNNISNNSAELKSALALYSCTSQVQAERHQQDLLSQGKSSLLSQCELPSGQKGWRVQIKECDGSENHCVRPLEEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4W2</accession>
    <name>D0Z4W2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type III secretion regulator YopN</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000195</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306573.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000195"/>
    <dbReference type="EnsemblBacteria" id="EEZ39179">
        <property type="protein sequence ID" value="EEZ39179"/>
        <property type="gene ID" value="VDA_000195"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5032VH1">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="932499at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019867">
        <property type="term" value="C:outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050709">
        <property type="term" value="P:negative regulation of protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030254">
        <property type="term" value="P:protein secretion by the type III secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010812">
        <property type="entry name" value="HrpJ-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013401">
        <property type="entry name" value="T3SS_LcrE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07201">
        <property type="entry name" value="HrpJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02568">
        <property type="entry name" value="LcrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HrpJ" evidence="1">
        <location>
            <begin position="60"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="297" mass="33097" checksum="A6FB5295260B0FA1" modified="2010-01-19" version="1">MSTINSQILTGNKFDAPIRSNLESSRTGASVNGNYRGETVRAHNATQSLFDAMEELTALGSEKAEKDLTKRKVKDGSIRVNEAHELVSDYLRKVPDLEKNQKIKDLATKMASGNLSTIAQLQAYLNGFSEEKSHQYLALQAVKKFLGTNPESKSLLALIDQAILTFEQNLDSWAQIDTEIRVSSFADEYSQEQGFSSLHQLRGFYRDTVHSYQGLSSAYKDVVERFGAKEVSTAVDFMLQGMSADLSVQGSSIDSVKLQLLMSDMQKLKTLNTLQDQVSNLYQMFKPQQANYGLSSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4W7</accession>
    <name>D0Z4W7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Yop virulence translocation protein R</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_000200</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the FliP/MopC/SpaP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306587.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000200"/>
    <dbReference type="EnsemblBacteria" id="EEZ39184">
        <property type="protein sequence ID" value="EEZ39184"/>
        <property type="gene ID" value="VDA_000200"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4790">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1049349at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005838">
        <property type="entry name" value="T3SS_IM_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005773">
        <property type="entry name" value="YopR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30587">
        <property type="entry name" value="PTHR30587"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00813">
        <property type="entry name" value="FliP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01302">
        <property type="entry name" value="TYPE3IMPPROT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01102">
        <property type="entry name" value="yscR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01060">
        <property type="entry name" value="FLIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01061">
        <property type="entry name" value="FLIP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="159"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ39184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="216" mass="24267" checksum="33ED594DC7764DF7" modified="2010-01-19" version="1">MIQLPDELNLIVTLALLALIPFIAMMATSFVKLAVVFSLLRNALGVQQIPPNMAMYGLAIILSIFIMAPVGFETYDYVTQHEISLEDSESIEGLIESGLQPYREFLKKHIRETESVFFTDAARTLWPQKYVDRLESDSLLLLLPAFTVSELTRAFEIGFLLYLPFIAIDLIVSNILLAMGMMMVSPMTISLPFKLLLFVLLDGWTKLTHGLVLSYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z513</accession>
    <name>D0Z513_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">Ribonucleoside-diphosphate reductase</fullName>
            <ecNumber evidence="4 12">1.17.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">VDA_000246</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>[thioredoxin]-disulfide + a 2'-deoxyribonucleoside 5'-diphosphate + H2O = [thioredoxin]-dithiol + a ribonucleoside 5'-diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23252"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:73316"/>
            <dbReference type="EC" id="1.17.4.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 12">Genetic information processing; DNA replication.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the ribonucleoside diphosphate reductase large chain family.</text>
    </comment>
    <dbReference type="EC" id="1.17.4.1" evidence="4 12"/>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000246"/>
    <dbReference type="EnsemblBacteria" id="EEZ39230">
        <property type="protein sequence ID" value="EEZ39230"/>
        <property type="gene ID" value="VDA_000246"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0209">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00326"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004748">
        <property type="term" value="F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005144">
        <property type="entry name" value="ATP-cone_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013346">
        <property type="entry name" value="NrdE_NrdA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000788">
        <property type="entry name" value="RNR_lg_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013509">
        <property type="entry name" value="RNR_lsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008926">
        <property type="entry name" value="RNR_R1-su_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039718">
        <property type="entry name" value="Rrm1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11573">
        <property type="entry name" value="PTHR11573"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03477">
        <property type="entry name" value="ATP-cone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02867">
        <property type="entry name" value="Ribonuc_red_lgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00317">
        <property type="entry name" value="Ribonuc_red_lgN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01183">
        <property type="entry name" value="RIBORDTASEM1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48168">
        <property type="entry name" value="SSF48168"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02506">
        <property type="entry name" value="NrdE_NrdA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51161">
        <property type="entry name" value="ATP_CONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00089">
        <property type="entry name" value="RIBORED_LARGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6 12" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 12 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-cone" evidence="13">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEZ39230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="647" mass="72323" checksum="612907CF1B08AD70" modified="2010-01-19" version="1">MLADGLKVEPIAVAQRVVSGLYDGIKVTEIDVFLAETAASLATEHPDYAKLAARVMVSSLQKETSGYATATRELSEIGILSSAYVDFVAKNQFALEDMIDYKRDYQFDYFGYKTLERSYLLKVKGVVVERPQDMFMRVAVAVAGDDLEEIRELYDLLSLCYYTHATPTLFNAGCKMQQLSSCFLLAMQEDSINGIYDTLKDCALISKSAGGIGLHIHNIRATGAPIIGTNGVSNGIVPMLKVFNETARYVDQGGGKRKGSFAVYLEPWHADIESFLDLRKNHGKEEFRARDLFLALWVPDLFMERVETDAEWTLFSPHNTKGLSDLYGAEFTQKYQEYERMGLGVKTIKARQLMTQIIESQAETGTPYMLYKDACNEKSNQKNLGTIKSSNLCAEIMEVSTPDETAACNLASLALPKFVTNTGFDFDKLHQVTKVAIKNLDRVIDVNYHPTDKIEKSNHAHRPVGLGIQGLADVFFKMHLPFDSEEALLLNRDIAETMYHASLEASCEIAKQKGTYSSYDGSPISHGQFQFDLWCEQPSSRWDWSQLKHQIAEHGVRNSLLIAQMPTASTAQILGNNEAFEAQTSNIYKRQTLSGEFIIINKYLVSDLEQRGLWTSKIRDAIILNNGSVQGIDAIPGSVWISKIIVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z520</accession>
    <name>D0Z520_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000253</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000253"/>
    <dbReference type="EnsemblBacteria" id="EEZ39237">
        <property type="protein sequence ID" value="EEZ39237"/>
        <property type="gene ID" value="VDA_000253"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1976239at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="1100" mass="127634" checksum="6C715304CD17342C" modified="2010-01-19" version="1">MDNNLKRAKVRKARKTHKIVSDVLQPKRFLGSKLEAKQASFHKFIFNSTNDEFEKAIRIIIKDNDIFSLLSQSKSDVSEIFKTLMFSDEHISKTNVIQLYFGIFSREIDKLILFNDTRKIIEDQFIKGNYSEVESLLSELTRNVGQSIWAINLQFNLYTAKKEYSKIDTFLEYLKNENDNNLFNDVVRVSGWKLQTVDSKLILESMVRRSNKEFIAGKALDIAAFYSLLCLPTSLYEDVDLLCSIYWLQRLPLVDLFDNFCKIIENAIIEESLNEDDKALLLTLFNEIGINIKSIKISKIISYLNGNITNEFECEFDSQINNYYEGNYNKVIDELESNLHETKNIITKINMYAKSYIYTKIKPNGLPDLLKEIIDNIISIYSLNNTNQSADHLVDLSIKYSSLELSDHILISIIKSAPYYFPSRTKEKIIAKSSFLNIPLTPLSYNLRTPPSMYIKDDGTSLSPHLKLKKKAIDSIKSPSVITSCLVDEFYSLSPINKDAIELKVQYLLKNNLKYELLSFSATELINNPNANVCIPLEEICSDINNNSIYTIDSVICSFFYNHFSELDGSSLLNEVFEEYFFTLNVKRPSEIIYTNLSNKQVFVLNVISKVDVMDYLGCFDDDSDLKIERINILNKLVSHQYLNQSDIDMECKLIVDDIIIESEAAKFNDSKIYVDTRFILNKRKSDIESLMYKYHSHSKDGDDNLVMLEDRTILKGIKNEALTRLFKVLLIEYMDNKEIGLDKNLSSEIRHGFFSNLMCSNLQKRQLITELDEKGFYKSNEYWREYYKIVHDSILDDIDDILIKFSNDFNSLIELAEQWMKTSLNDDEPNRIFTFNFETTDFDRVRAVLDNQGTAEQVSNEIFNVFNNKLLICLEKIKIKLNEVFMEEVDRLFSKLIDDINLCKHGTALTDLFDEIRLANTEVKEDVRTVCEWFSIRNNTDVDSFEISKTVQLAERYFHQISNVNINVDINIKKNFLVDGSHLYALVLTFINCFNNCFKHSSSCAKSIDVLIDENNKDSGFIINIRNKIDDKTKEILLEGKLDIIIKQLIDMNNHDLLVNEGGSGLYKSLHDLKMIDINYNMTLYVFDDYFNVEIKYEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z527</accession>
    <name>D0Z527_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Antirestriction protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000260</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000260"/>
    <dbReference type="EnsemblBacteria" id="EEZ39244">
        <property type="protein sequence ID" value="EEZ39244"/>
        <property type="gene ID" value="VDA_000260"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4227">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1509644at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017113">
        <property type="entry name" value="Antirestriction_ArdC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013610">
        <property type="entry name" value="ArdC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041459">
        <property type="entry name" value="MPTase-PolyVal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08401">
        <property type="entry name" value="ArdcN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18818">
        <property type="entry name" value="MPTase-PolyVal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037112">
        <property type="entry name" value="Antirestriction_ArdC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ArdcN" evidence="1">
        <location>
            <begin position="2"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="MPTase-PolyVal" evidence="2">
        <location>
            <begin position="143"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="276" mass="31505" checksum="A02D4B4E4C582868" modified="2010-01-19" version="1">MYQLVTDRVIAALEQGVKPWSCPWERSNQSTMLPMNLKTGARYTGINVLLLWSSAAERGFTSPYWLTYKQAQELGGNVVKGQKGTTIVFYTLWEKEDGDGKLDRIPMLKTFTVFNLDQLENIDKPDLISEPTYTKNEFNLLPHVEAAIEKTHAQIEYRGSRAFYSLGDDKIVIPNRDRFHSQSDLYATIWHELVHFTGHPSRLDRNIMNQFGSKDYAVEELVAELGAAFCCADLGIIGEAQHESYIASWLHRLRNDKRFIFKAASLASKAHQFLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z529</accession>
    <name>D0Z529_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000262</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306767.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39246">
        <property type="protein sequence ID" value="EEZ39246"/>
        <property type="gene ID" value="VDA_000262"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2224301at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="181" mass="20609" checksum="0C6DC12115F9E5DB" modified="2010-01-19" version="1">MNTRSKTATKFYTSERADNSVQIGLAGREVDSESVIREGNATHRLSSLEVSQAPALRAPCAAHISRANARKANIFKRAWSLAAQKALRFGGEKCTYFAACLKVVYRQIKLTHTESRQQYGDLMKRNNEYLKQLKERLSRYESKPDLLHREQAIADLLPRIKNAQVRQSYYVDLIFCAGIEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5B2</accession>
    <name>D0Z5B2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000162</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005307022.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000004.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39146">
        <property type="protein sequence ID" value="EEZ39146"/>
        <property type="gene ID" value="VDA_000162"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502ZB0I">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1451426at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="356" mass="37756" checksum="29354A4A41589A96" modified="2010-01-19" version="1">MPLPFILAGAAAVVAGYGAKKGYDGYQDKTAANEILESAKNRYEIEKEAFDYTNDKTTESLTKLGELQLQIGEDFQSFRTIAKSLLEKMNENSSKDIVIDFPQHKLNKIDGLALSTTAYMGKVAGAGVAGAAAAYAVYGGVMALAAASTGTPIAALSGAAAYNATMAAIGGGSLAAGGFGMAGGAMVLGGVVAAPIIAIAGWAFASHAEEALSDARKVRDEVDDAVDKMNKGSEQLAKTRAYVENIYTETSRIHSEFCVYFEHLKEMEQYINRGNDLDKVSNEVILTIQNGYQIAAILTDIITTPLFKPKMDAAGQVVMNADNIVEIETDQDGMQVLNEQAIQQALIKADADLKQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5I9</accession>
    <name>D0Z5I9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATPase_AAA_core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000007</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000007">
        <property type="protein sequence ID" value="EEZ39000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005307240.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000007.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39000">
        <property type="protein sequence ID" value="EEZ39000"/>
        <property type="gene ID" value="VDA_000007"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1106">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="318943at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13304">
        <property type="entry name" value="AAA_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase_AAA_core" evidence="1">
        <location>
            <begin position="33"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="458" mass="51578" checksum="C0D3F5B25756233D" modified="2010-01-19" version="1">MALDKIEINGYRGFNNEVSVKFAVPNGEPGSGLTIITGANNSGKSSIIECFKARSGYQSPSFTVGRRNSDTDRVEIKFHFNDRIEVIKSTQKGSSETVRENVKQDESIYVLPSRRAFAPFFGRGNGYDRNTYLMNEELQAQRSSTMNNFQYRLFNTLKNQTAFNEILHRVLPSKPEWSIDQSDEGNYFLKFYNGKYAHSSDGLGEGIVSVFSIVDSLYDSKKGDIIVIDEPELSLHPMLQKRIFSLLKDYARDRQIVISTHSPYFVDIPSLTCGGSLIRVVNHGEGSVIYQLSTHGQTILKKLSSGNLYNPHTFGLDAKELFFLEDNIVVVEGQEDVLLLPNVAEQLCMEIDASFFGWGAGGASNIEHICELLKELGFRKVSGILDGDKASLVPKLKEKFPNYHYVHIAADDIRTKPERKASDCVEGLLDKKRNLKESYKEHTKALFVGLNAYMKERF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-06-02" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVI8</accession>
    <name>D0YVI8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Tim44 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001568</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40542">
        <property type="protein sequence ID" value="EEZ40542"/>
        <property type="gene ID" value="VDA_001568"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4395">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007379">
        <property type="entry name" value="Tim44-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04280">
        <property type="entry name" value="Tim44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00978">
        <property type="entry name" value="Tim44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="Tim44" evidence="3">
        <location>
            <begin position="141"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="272" mass="29866" checksum="C810261D3628753B" modified="2010-01-19" version="1">MSFAAPHVEAKKFGGGKSFGKSYKTAPMKQQQKPQQTDTIGKKATNTQSGKKGLMGGLLGGLLAGGLIAAFFGGAFDGINFMDILIIGVIAFVIFKLLKGMRANKGTPMGHREAYAGNSPQQRNQQQAQFRQAANGASTGFSPDSDVPFNLPPNFNLNAFLNGSREHYRTIQEAWNKNDLAKIREYVSPALLNDLMAERAKLNGEQHTEVMYVDAEVVRADYDANMAQLSIQFSGRYKDSHEGVEEDITDVWHLERDLRTPNAPWLIVGIQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVS8</accession>
    <name>D0YVS8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001993</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299116.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001993"/>
    <dbReference type="EnsemblBacteria" id="EEZ40961">
        <property type="protein sequence ID" value="EEZ40961"/>
        <property type="gene ID" value="VDA_001993"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0582">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="43148at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0229">DNA integration</keyword>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="727" mass="83151" checksum="B72BBA5A4062E08B" modified="2010-01-19" version="1">MIVLKPLQKNEALPLGSAETNAPCDASSAAVKLALKSGDYAFLENITVYEDRKIVIKFSSDVWEFNKSTLNNKSIANLNFHLNKELGANVTPIASKEAERNFINQIKAYALAVIYHSAEVVELSTLTARITNLKCFASMALRYGLNGFEDITEETLSDWIADGFDLSQQLMFVGLNSLRKYGGTLSFEVQLPHLTHKKLNIKKADTQQNEVIPFRIWSELVNSFIKEVQEAYKHRHELQKLTEEMLKAGDKAEKKAISNIRVGARSFDKREKERLETSEFLSALKAEGINLIDYEQNDRWLQLFNENKVILSLNNYTKKLTFKFQGKELRFAEAKEYLSRICNVCSWLALLLSGMRIDELYALHPQFGAQDIDLPIGNSLRKKETIYIFTTRQSKITPTTQKLDDTYVTTVDGYKAFHVLNALSAPYRAYIKEVKSDTMFVDLKRASSHRQRTKTALGRTLIRFIAKESGVDMSLTQVDIDNLSISEGKQTHNVDEQYKITPHQARRSLAYYLVGYELCSFPALKQQLGHFSMAMTRWYARNATKYPTFWKEVSDLRISEKADICVRIFKRLANGERLAGGKGAAYLREIQNNPNYFEDGTNKRLLTKEYWEEKLRTGKQHIHAIAPSMYCSNDKCSMRLAIDLTECVDCEFDYIENVAYAESARMNAMYRLERLASEGELNPSVASSCYMTILASERIMKDLDFKYEPYQVPEAVKSLVIDFKVMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW03</accession>
    <name>D0YW03_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CcsA-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001308</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001308"/>
    <dbReference type="EnsemblBacteria" id="EEZ40283">
        <property type="protein sequence ID" value="EEZ40283"/>
        <property type="gene ID" value="VDA_001308"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4137">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002541">
        <property type="entry name" value="Cyt_c_assembly"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01578">
        <property type="entry name" value="Cytochrom_C_asm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="201"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="235"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="259"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrom_C_asm" evidence="2">
        <location>
            <begin position="64"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="290" mass="31972" checksum="8F53E6CF0A0EC6E4" modified="2010-01-19" version="1">MSARYNCHSRSSKTSYVCYGVFSVIMDILIAVAAIGCYIAALAFIIPGLSNSNGIKTRPVFISALLAIALHILLLKDLILGVHGQNLSILNVASLISVIIAIITTFAMLKMRIWFVLPVVYSFAAINLAAATLLPGVFITHLEANPQVLLHISLALFSYSTLMIATLYAIQLAWLDNKLKSKKSLQLNPNIPPLMMVERQLFKLILVGNGLLTVTLLTGLLFLQDMFAQGKTHKAVLSILAWLVYSVLLWGHYRQGWRGRRVIWISLVGAFLLTLAYFGSRFVKEIIIGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW22</accession>
    <name>D0YW22_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001284</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40260">
        <property type="protein sequence ID" value="EEZ40260"/>
        <property type="gene ID" value="VDA_001284"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1408709at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021352">
        <property type="entry name" value="DUF2971"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11185">
        <property type="entry name" value="DUF2971"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="247" mass="28846" checksum="50AE3BA8D00F27BC" modified="2010-01-19" version="1">MRREGSNLYLYKFQRVDKYSVANLLNTCLYFAKPANLNDPTESLFELELPNRDDKYCPDLEHFKNIAALSMAVDMGRPYELSDSLFHWSYYADGLRGFCMVFDKQRLVEEFNDETLVHDYIGYQPISNILIGDNLITEESGLEEVPGKNFKHDNFGRLVTSAYMNKPDSYANEKEYRFIKTGDGELKYNHLNTLREVIIGSKMSDHDRKLLESIIKLTGQDSKIKYANIRKNRYRIFIENDLVLESI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW35</accession>
    <name>D0YW35_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative potassium channel protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001298</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001298"/>
    <dbReference type="EnsemblBacteria" id="EEZ40273">
        <property type="protein sequence ID" value="EEZ40273"/>
        <property type="gene ID" value="VDA_001298"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013099">
        <property type="entry name" value="K_chnl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003148">
        <property type="entry name" value="RCK_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07885">
        <property type="entry name" value="Ion_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02254">
        <property type="entry name" value="TrkA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51201">
        <property type="entry name" value="RCK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0407">Ion channel</keyword>
    <keyword evidence="1" id="KW-0406">Ion transport</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="66"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="96"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="119"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="147"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="207"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="253"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="RCK N-terminal" evidence="3">
        <location>
            <begin position="252"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="410" mass="45436" checksum="6D7C9223E7DAAD05" modified="2010-01-19" version="1">MSSCRTFWHRCWRFIRESFTTLYAIRHIFIALLVLGNSAFILHVIYGLPIDLVSIFNVKNYEDLNLTFLINAPYFMLGVFIAMSTIGLFFRARISWVICFTLLIINAFYAMQLRPSEEYNFHYSLFTIAVLFLNRKHFSKSSVAAGTIFALISMISLMLTSTYGALYFGDGYKPPINDLSTALYYAIETMTTVGYGDIVPVSEPARLFTISVIIAGITVFATSLTSVLGPAVQSGYERLTKGKTKKMKRKNHFIICGLSSLALNTIQQLIQRKQPVTVIVSPRTQQAAKDLLEDLDVVVGDYSDGSVLKQAGVMDAKALLALSDDDADNAFIVLSAIELKTDAHNVALVNDSKNINKVKSVNPDIVISPQQFASDILARVLNGETIDSESIVSSLLNSVQGLNEKQISKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW84</accession>
    <name>D0YW84_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycine cleavage system transcriptional activator GcvA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001343</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297886.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001343"/>
    <dbReference type="EnsemblBacteria" id="EEZ40318">
        <property type="protein sequence ID" value="EEZ40318"/>
        <property type="gene ID" value="VDA_001343"/>
    </dbReference>
    <dbReference type="GeneID" id="57339755"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="846433at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="6"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="303" mass="34202" checksum="949C71EFB27249A5" modified="2010-01-19" version="1">MSRRLPPLNSLKVFEAAARHLSFTRAAEELFVTQAAVSHQIKALEEFLGLKLFRRRNRSLLLTEEGQSYFLDIKDIFSSIADATDKVLERGAKGALTISLPPSFAIQWLVPRLIDFNEQHPDIDVRIKAVDLDEGSLTDDVDVAIYYGRGNWSGLRADKLYQEFMMPLCSPMVLTGPKPLRTLDDLKNHTLLHDTSRKEWKNYVRQYDIKGVNVNQGPIFSHSTMVLQAAAHGQGIALGNNVLAQPELEAGRLVCPFDEVLMSKNAFYLVCQEKQADSGRIQAFRDWVLAKARSEQEDMPDVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWA9</accession>
    <name>D0YWA9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Dephospho-CoA kinase</fullName>
            <ecNumber evidence="2">2.7.1.24</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Dephosphocoenzyme A kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">coaE</name>
        <name evidence="3" type="ORF">VDA_001187</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>3'-dephospho-CoA + ATP = ADP + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18245"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57328"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.24"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 5/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the CoaE family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.24" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297596.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001187"/>
    <dbReference type="EnsemblBacteria" id="EEZ40165">
        <property type="protein sequence ID" value="EEZ40165"/>
        <property type="gene ID" value="VDA_001187"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0237">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1515383at2"/>
    <dbReference type="UniPathway" id="UPA00241">
        <property type="reaction ID" value="UER00356"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004140">
        <property type="term" value="F:dephospho-CoA kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00376">
        <property type="entry name" value="Dephospho_CoA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001977">
        <property type="entry name" value="Depp_CoAkinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01121">
        <property type="entry name" value="CoaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00152">
        <property type="entry name" value="TIGR00152"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51219">
        <property type="entry name" value="DPCK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0173">Coenzyme A biosynthesis</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="12"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="200" mass="22315" checksum="8D25C3CFA95DA410" modified="2010-01-19" version="1">MSFVVGLTGGIGSGKTTVANLFARYGVDLIDADMIARDVVAPNSIGLAAIIDKFGADITLENGELDRAQLRRLIFSKPEQKEWLNQLLHPMIRQQMLAQIQASTSPYCLLIVPLMVENNLQALTQRLLVVDVDEQVQIQRTQQRDKVPLEQVKKILASQASRSERLAAADDVITNNDDEQALYPQVEKLHQYYLALSQSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWD7</accession>
    <name>D0YWD7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Efflux pump membrane transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_001407</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 6">Cell inner membrane</location>
            <topology evidence="2 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298015.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001407"/>
    <dbReference type="EnsemblBacteria" id="EEZ40382">
        <property type="protein sequence ID" value="EEZ40382"/>
        <property type="gene ID" value="VDA_001407"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0841">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="91817at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042908">
        <property type="term" value="P:xenobiotic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004764">
        <property type="entry name" value="HAE1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00915">
        <property type="entry name" value="2A0602"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="340"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="366"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="396"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="437"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="470"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="536"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="872"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="896"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="922"/>
            <end position="946"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="967"/>
            <end position="987"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="1007"/>
            <end position="1029"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="1036" mass="112341" checksum="520BC34098BCC787" modified="2010-01-19" version="1">MSRFFIGRPIFAWVIAIIIMLAGTMAILTLPVAQYPTIAPPAIQISATYQGASAKTVEDSVTQVIEQNMTGLDNLMYMSSTSDSSGNASITLTFEAGTDPDIAQVQVQNNLQRATSQLPTEVQQLGISVRKSTSSFMSVTAFVSTDNSMTGQDIMDYVSSRVKDPVSRVAGVGDVMVFGTQYAMRIWLDPAKLNSYNLTPIDIVNAIRQQNTQVTVGQIGGAPAVKGQMINATITARNRLESVQQFKDILLRVNKDGSQIRIKDVARVELGGESSDFITRFDGKPASGIGIKLATGANALDTQKAVDAKLEELSANFPQGLKMYKAMDTNPFVKLSIEEVVSTLFEAIVLVFLVMYLFLQNIRATLIPTIAVPVVLLGTFGVMAACGFTINTLTMFGLVLAIGLLVDDAIVVVENVERVMSEEGLSPVEATKKSMGQISGALVGVAMVLSAVFVPMAFMTGSTGAIYRQFSLTIVAAMVLSVLVAMILTPALCATMLKAGDADHGEKKGFFGWFNRIFDRTANGYQSSVAGILKRSGRFVIVYLLLLPVIGWMFKSIPSSFLPNEDQGNFMVMVQLPPGASLERSQKVMDEVTHYFETEEKSTVESVFTVSGFSFVGQAQNAGMAFVGLKDWSERTAPGTDVNSIIKRAMIHFKDNQDAMIFAVNPPAIRELGQASGFDFFLEDRAGLGHEKLLQARNQLLGMANQNPALQKVRPNGLEDNSQFFIDLDYEKAKALGIDINDINKTLSIAWGSSYVNDFIDRGRIKKVYVQADAPYRMSPKDISDWYVRNNKGEMVPFSAFSQSHWGFGSPRLARYNGNSSFEILGEAAPGYSTGEAMAAIEQIASKLPEGITVSWTGMSYQERLAGSQAPMLYALSMLVVFLCLAALYESWSVPIAVILVVPLGVLGALAATMFRGLENDVYFQVGLLTTIGLAAKNAILIVEFAKELHEKGMGLIEATVEACRMRLRPIIMTSLAFILGVLPLVMSSGAGANSRHAIGTSVMGGMISATVLAIFFVPLFFVLITKLFTRKKAEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWE5</accession>
    <name>D0YWE5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Yip1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_001393</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297990.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001393"/>
    <dbReference type="EnsemblBacteria" id="EEZ40368">
        <property type="protein sequence ID" value="EEZ40368"/>
        <property type="gene ID" value="VDA_001393"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5030ECJ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1075898at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006977">
        <property type="entry name" value="Yip1_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04893">
        <property type="entry name" value="Yip1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="93"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="123"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="174"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="208"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="Yip1" evidence="6">
        <location>
            <begin position="13"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="230" mass="25984" checksum="21F5321613108C42" modified="2010-01-19" version="1">MTPSKNPLIAVLDLFRSPIDCFAAVYERPKWAFFAYLIIIFGPFILWGGYFDHVDMPWLQQSLAAQLSNVDHEIQQAWMTKEVLLAGEVFSDVLGRTAMIFLLALWLYFSTKASTYSHGYGKWLAASCFIMLPAFLGDIASYVNILFNTHNILPNAADLNSLNGLLKLPLNSPWSPFATTIPLLTPWYIALTYAAITAWTDYDRAKAVIVALLPWVMTIIIWPIMILVSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWF6</accession>
    <name>D0YWF6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glycine cleavage system transcriptional repressor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001415</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298023.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001415"/>
    <dbReference type="EnsemblBacteria" id="EEZ40389">
        <property type="protein sequence ID" value="EEZ40389"/>
        <property type="gene ID" value="VDA_001415"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2716">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1859752at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016867">
        <property type="entry name" value="GcvR"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028103">
        <property type="entry name" value="GcvR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0678">Repressor</keyword>
    <keyword evidence="1" id="KW-0804">Transcription</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR028103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="185" mass="20962" checksum="E7728CA31A597FBE" modified="2010-01-19" version="1">MEHYLVITAVGTDRPGITNEVTQLVTQCGCNIVDSRIALFGSEFTLIMLLSGNNNAITRVESTLPLKGQEHDLITVMKRTNKHKPRFFPYTADFYIEARDTPGLIEHFTKFMASRQLDISSLSAHTQENQDPSCDFDTLILQIYSNLPESCNTEFLEQEFQALCHQLEVIGSINITEHQQIHSDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWH0</accession>
    <name>D0YWH0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">LPS-assembly lipoprotein LptE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">lptE</name>
        <name evidence="4" type="ORF">VDA_001429</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the LptE lipoprotein family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001429"/>
    <dbReference type="EnsemblBacteria" id="EEZ40403">
        <property type="protein sequence ID" value="EEZ40403"/>
        <property type="gene ID" value="VDA_001429"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2980">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043165">
        <property type="term" value="P:Gram-negative-bacterium-type cell outer membrane assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01186">
        <property type="entry name" value="LPS_assembly_LptE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007485">
        <property type="entry name" value="LPS_assembly_LptE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38098">
        <property type="entry name" value="PTHR38098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04390">
        <property type="entry name" value="LptE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="4" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="1 2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="181"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="207"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="186"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="228" mass="25459" checksum="BB84A63319293E82" modified="2010-01-19" version="1">MTRYFSMKQASRFLMVTLLALATASCGFHLRGNYMLPEGIAKLSLTSFDPYGQLTRQVKSQFKMHGIQQVTPAKNVPNLNIVSESDGDRTLSLYQNNGRAEYELTYSVNYSVSIPNHGVENFTTRVTRTFLDNPLTALAKSVEEDELKQVMRQQAAQQIMRQLARLTVTFNKIAEEEHNDALADTLPGKSSVTTEKLSDKQAADTMFAQPQSQSLPQINSISEGTNLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWI4</accession>
    <name>D0YWI4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Heme chaperone HemW</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">VDA_001226</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297677.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001226"/>
    <dbReference type="EnsemblBacteria" id="EEZ40204">
        <property type="protein sequence ID" value="EEZ40204"/>
        <property type="gene ID" value="VDA_001226"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0635">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1130951at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004109">
        <property type="term" value="F:coproporphyrinogen oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006779">
        <property type="term" value="P:porphyrin-containing compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034505">
        <property type="entry name" value="Coproporphyrinogen-III_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010723">
        <property type="entry name" value="HemN_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004559">
        <property type="entry name" value="HemW-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13932">
        <property type="entry name" value="PTHR13932"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06969">
        <property type="entry name" value="HemN_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00562">
        <property type="entry name" value="HemN-like__clustered_with_heat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00539">
        <property type="entry name" value="hemN_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="9 10" id="KW-0143">Chaperone</keyword>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 10" id="KW-0349">Heme</keyword>
    <keyword evidence="7 10" id="KW-0408">Iron</keyword>
    <keyword evidence="8 10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="11">
        <location>
            <begin position="1"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU364116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ40204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="386" mass="43511" checksum="FCBD1B3E2B0DBB70" modified="2010-01-19" version="1">MLIPPPLSLYVHIPWCVQKCPYCDFNSHALKAEIPELDYIDALLDDLSTDLLAYHLEHGERKLHSIFIGGGTPSLISPEEIARLLQGIEARIPFSDDIEITMEANPGTVEAGRFQAYQQAGVNRISIGIQSFQDEKLKRLGRIHGAQEAITAAKLAAEAGLNSFNIDLMHGLPDQSINDALADLAQAIGLNPPHLSWYQLTIEPNTLFYSQPPTLPDDDDLWDIFEQGHKMLTYAGYVQYEISGYSKPGKQCQHNLNYWRFGDYLGIGCGSHGKISFDDGRIVRTIKVKHPRGYLNPEKAYLDQETIVANDERPFEFFMNRFRLLEACPKQDFVARTGLPLTHIQGAIDWALAQNYLTESDTHWQITEHGKLFLNDLLAAFVEDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWJ6</accession>
    <name>D0YWJ6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">S-adenosylmethionine synthase</fullName>
            <shortName evidence="11">AdoMet synthase</shortName>
            <ecNumber evidence="11">2.5.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">MAT</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Methionine adenosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">metK</name>
        <name evidence="17" type="ORF">VDA_001238</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>ATP + H2O + L-methionine = diphosphate + phosphate + S-adenosyl-L-methionine</text>
            <dbReference type="Rhea" id="RHEA:21080"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="EC" id="2.5.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
        <text evidence="11">Binds 1 potassium ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="11">Binds 2 divalent ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Amino-acid biosynthesis; S-adenosyl-L-methionine biosynthesis; S-adenosyl-L-methionine from L-methionine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Homotetramer; dimer of dimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11 12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11 13">Belongs to the AdoMet synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.6" evidence="11"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297702.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001238"/>
    <dbReference type="EnsemblBacteria" id="EEZ40216">
        <property type="protein sequence ID" value="EEZ40216"/>
        <property type="gene ID" value="VDA_001238"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0192">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1024388at2"/>
    <dbReference type="UniPathway" id="UPA00315">
        <property type="reaction ID" value="UER00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004478">
        <property type="term" value="F:methionine adenosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006556">
        <property type="term" value="P:S-adenosylmethionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00086">
        <property type="entry name" value="S_AdoMet_synth1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022631">
        <property type="entry name" value="ADOMET_SYNTHASE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022630">
        <property type="entry name" value="S-AdoMet_synt_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022629">
        <property type="entry name" value="S-AdoMet_synt_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022628">
        <property type="entry name" value="S-AdoMet_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002133">
        <property type="entry name" value="S-AdoMet_synthetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022636">
        <property type="entry name" value="S-AdoMet_synthetase_sfam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11964">
        <property type="entry name" value="PTHR11964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02773">
        <property type="entry name" value="S-AdoMet_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02772">
        <property type="entry name" value="S-AdoMet_synt_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00438">
        <property type="entry name" value="S-AdoMet_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000497">
        <property type="entry name" value="MAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55973">
        <property type="entry name" value="SSF55973"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01034">
        <property type="entry name" value="metK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00376">
        <property type="entry name" value="ADOMET_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00377">
        <property type="entry name" value="ADOMET_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 11 12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 11 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 11" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="10 11 12" id="KW-0630">Potassium</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11 17" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="S-AdoMet_synt_N" evidence="14">
        <location>
            <begin position="4"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="S-AdoMet_synt_M" evidence="15">
        <location>
            <begin position="114"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="S-AdoMet_synt_C" evidence="16">
        <location>
            <begin position="233"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Flexible loop" evidence="11">
        <location>
            <begin position="99"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="17"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="164"/>
            <end position="166"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="230"/>
            <end position="231"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="239"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="245"/>
            <end position="246"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="262"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <note>ligand shared between two neighboring subunits</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="266"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <note>ligand shared between two neighboring subunits</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="270"/>
        </location>
        <ligand>
            <name>L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF02773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EEZ40216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="384" mass="42085" checksum="6C7F089A896A57A2" modified="2010-01-19" version="1">MAKHLFTSESVSEGHPDKIADQISDAVLDAILEQDPKARVACETYVKTGMVMVGGEITTSAWVDIEELTRETVREIGYVHSDMGFDANSCAILNTIGKQSPDINQGVDKTDPKEQGAGDQGIMFGYATNETDVLMPAPITYSHLLMQRQAEVRKNGTLPWLRPDAKSQVTFQYDNGKIVGIDAVVLSTQHSDSISTPDLREAVMEEIIRPVLPAEWLSRDTKYFINPTGRFVIGGPMGDCGLTGRKIIVDTYGGAARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGMADRCEIQLSYAIGVADPTSIMVETFGTEKVAQEIIIEAVRQHFDLRPYGLQEMLNLLQPIYKKTAAYGHFGREEFPWEKTDKVAALRDFAKLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWM0</accession>
    <name>D0YWM0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase</fullName>
            <ecNumber evidence="6">2.7.8.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Undecaprenyl-phosphate GlcNAc-1-phosphate transferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">wecA</name>
        <name evidence="7" type="ORF">VDA_001511</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>di-trans,octa-cis-undecaprenyl phosphate + UDP-N-acetyl-alpha-D-glucosamine = N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate + UMP</text>
            <dbReference type="Rhea" id="RHEA:28090"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:60392"/>
            <dbReference type="ChEBI" id="CHEBI:62959"/>
            <dbReference type="EC" id="2.7.8.33"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6">Bacterial outer membrane biogenesis; LPS O-antigen biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell inner membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the glycosyltransferase 4 family. WecA subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.33" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298187.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001511"/>
    <dbReference type="EnsemblBacteria" id="EEZ40485">
        <property type="protein sequence ID" value="EEZ40485"/>
        <property type="gene ID" value="VDA_001511"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0472">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="728505at2"/>
    <dbReference type="UniPathway" id="UPA00281"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009276">
        <property type="term" value="C:Gram-negative-bacterium-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008963">
        <property type="term" value="F:phospho-N-acetylmuramoyl-pentapeptide-transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036380">
        <property type="term" value="F:UDP-N-acetylglucosamine-undecaprenyl-phosphate N-acetylglucosaminephosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009243">
        <property type="term" value="P:O antigen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02030">
        <property type="entry name" value="WecA_Gammaproteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012750">
        <property type="entry name" value="ECA_WecA-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000715">
        <property type="entry name" value="Glycosyl_transferase_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22926">
        <property type="entry name" value="PTHR22926"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00953">
        <property type="entry name" value="Glycos_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02380">
        <property type="entry name" value="ECA_wecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-0448">Lipopolysaccharide biosynthesis</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0464">Manganese</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="68"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="96"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="126"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="157"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="181"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="210"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="244"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="285"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="321"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="360" mass="39567" checksum="8FB3A0EE99DDF67F" modified="2010-01-19" version="1">MNNAYLFVFIMSFATLFIMRKVAKKIGLVDKPNARKLHQGVIPLVGGISVYLSLLVGFTLFLPMVPSLQLYLSCAAILIVLGALDDYFDISFKIRLVVQAGISLAMILIGQHSLHNFGYLMGSETIALGEIAGSIITIIAVIGAINAFNMVDGIDGLLGGLASVTFTALGTVFYISGNSYLATVCLLIVTALIPYIMLNLGFPLGRRFKVFMGDAGSMFIGFSVVWMLIRGTQEPEVIAFKPVTALWLIAIPLMDMATIMIRRIRKGHSPFKPDREHLHHICQRIGLSPLMTLFVICFMASICAGIGIWADLSGVPESTMFIAFLILFAVYIMAISYIWRITTWVNKLFGRQIATQEAHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWM7</accession>
    <name>D0YWM7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">UDP-glucose 6-dehydrogenase</fullName>
            <ecNumber evidence="4 7">1.1.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">VDA_001518</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>H2O + 2 NAD(+) + UDP-alpha-D-glucose = 3 H(+) + 2 NADH + UDP-alpha-D-glucuronate</text>
            <dbReference type="Rhea" id="RHEA:23596"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58052"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="1.1.1.22"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Nucleotide-sugar biosynthesis; UDP-alpha-D-glucuronate biosynthesis; UDP-alpha-D-glucuronate from UDP-alpha-D-glucose: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.22" evidence="4 7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298201.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001518"/>
    <dbReference type="EnsemblBacteria" id="EEZ40492">
        <property type="protein sequence ID" value="EEZ40492"/>
        <property type="gene ID" value="VDA_001518"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1004">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="647136at2"/>
    <dbReference type="UniPathway" id="UPA00038">
        <property type="reaction ID" value="UER00491"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003979">
        <property type="term" value="F:UDP-glucose 6-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000271">
        <property type="term" value="P:polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006065">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
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        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017476">
        <property type="entry name" value="UDP-Glc/GDP-Man"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014027">
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="UDPglc_DH_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00984">
        <property type="entry name" value="UDPG_MGDP_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="UDPglc_GDPman_dh"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52413">
        <property type="entry name" value="SSF52413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03026">
        <property type="entry name" value="NDP-sugDHase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 10" id="KW-0520">NAD</keyword>
    <keyword evidence="5 7 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDPG_MGDP_dh_C" evidence="11">
        <location>
            <begin position="301"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="143"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="243"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8">
        <location>
            <position position="254"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="251"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="257"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="307"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="308"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="315"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="389"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR000124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR500134-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR500134-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR500134-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ40492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="389" mass="43592" checksum="6E8C09B2F226CC64" modified="2010-01-19" version="1">MYKIAIAGTGYVGLSNAMLLAQYNEVIAVDIVDEKISLLNDKISPIVDKEIEDFLQNKSLNFYATLDKKLAYENADFVIISTPTDYDTVNDFFNTSSVEAVIKDVMEINPNAVMVIKSTVPVGYTQQIKEQYNCNNIIFSPEFLREGRALYDNLYPSRVIVGEKSERAKVFANLLVEGAIKQDIPVLFTDSTEAEAVKLFSNTYLAMRVAYFNELDTYAASNGLDTRQIIEGVGLDPRIGNHYNNPSFGYGGYCLPKDTKQLRANYRDVPNNMIGAIVDANTTRKDFIADSIIAKNPQRVGIYRLIMKAGSDNFRASSIQGIMKRIKAKGIEVVIYEPVLHEKEFFNSLVMVNLAEFKQQCDVIVSNRMVEELADVAAKVYTRDLFGAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWQ4</accession>
    <name>D0YWQ4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Serine transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_001450</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001450"/>
    <dbReference type="EnsemblBacteria" id="EEZ40424">
        <property type="protein sequence ID" value="EEZ40424"/>
        <property type="gene ID" value="VDA_001450"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003333">
        <property type="term" value="P:amino acid transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018227">
        <property type="entry name" value="Amino_acid_transport_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03222">
        <property type="entry name" value="Trp_Tyr_perm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="138"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="162"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="202"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="246"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="292"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="335"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="363"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="394"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ40424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="417" mass="45868" checksum="805174E8F91920D7" modified="2010-01-19" version="1">MSQELPLEVSRSQSVWNKADTSWMLSLFGTAVGAGILFLPINIGAGGFWPLVVMALIAGPMTFWAHRGLARFVLSSAKKDSDFTDVVEEHFGAKSGRLISLLYFLSIFPILLIYGVGLTNTVDSFIVNQLHMAAPSRVVLSGVLVFAMIAVMMAGEKVMLKAFEVIVYPLAAILAGLSLYLIPSWTLPDFSVVPTTKDFISSVWLAVPVVVFAFSHTPVISGFANTQRRQYGEQGFQKTEQILKRTSIMLLSFVLFFVFSCVLSLSPDQLQQAKAQNVSVLSFLANVHDNHFIVLLGPFIAFIAITSSFLGHFMGARESFNGLVQKQTSWSEKKVDRLGVVLMFFSIWFAAVMNPSILGMMEAISGPIIAMILFIMPMIAVYKVDALKHYRGKFSTIFILLMGALAVSAILFSMVIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWV1</accession>
    <name>D0YWV1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hypothetical response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001543</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298245.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001543"/>
    <dbReference type="EnsemblBacteria" id="EEZ40517">
        <property type="protein sequence ID" value="EEZ40517"/>
        <property type="gene ID" value="VDA_001543"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="8"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="350" mass="38880" checksum="FDC978799A8AD33D" modified="2010-01-19" version="1">MSLLEGKDILIVEDDPIFRNMVSAFLQHQGCSVRYAEDGVQGLKALQNAIPDLMLCDLSMPIMSGMEFVEEAVVQYPMLPIIVVSGTGAMADVAAALRLGVKDYLVKPLDNFLVLKSAMMTVFKAADIQQGNTGDASTTWPQRNEMVDEELAWHFEELDNDPTAARELLTGLMPDIQSSCGSWQLNYYVLQNADKAPVLLDYTWLMDGRLAFYVIDCSSCPSHGTATALLIRAFFNDYLRQQRVHESHIVELLQEIEKHLKSSRYTSNIKCIFGLFDVVNHQLNLMPAGIGGSVQTSEENHTISGQAWLGQKAFFNQGSRLKIAPSGVRLSLSEIDCANFSITLQRIPTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWV3</accession>
    <name>D0YWV3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transcription antitermination protein RfaH</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rfaH</name>
        <name evidence="6" type="ORF">VDA_001545</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Interacts with both the nontemplate DNA and the RNA polymerase (RNAP).</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RfaH family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001545"/>
    <dbReference type="EnsemblBacteria" id="EEZ40519">
        <property type="protein sequence ID" value="EEZ40519"/>
        <property type="gene ID" value="VDA_001545"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0250">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001073">
        <property type="term" value="F:transcription antitermination factor activity, DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00951">
        <property type="entry name" value="RfaH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006645">
        <property type="entry name" value="NGN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036735">
        <property type="entry name" value="NGN_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043425">
        <property type="entry name" value="NusG-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010215">
        <property type="entry name" value="Transcription_antiterm_RfaH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30265">
        <property type="entry name" value="PTHR30265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02357">
        <property type="entry name" value="NusG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00738">
        <property type="entry name" value="NGN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82679">
        <property type="entry name" value="SSF82679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01955">
        <property type="entry name" value="RfaH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0804">Transcription</keyword>
    <keyword evidence="1 4" id="KW-0889">Transcription antitermination</keyword>
    <keyword evidence="2 4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="NGN" evidence="5">
        <location>
            <begin position="36"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="200" mass="23218" checksum="51813A9A61751A3A" modified="2010-01-19" version="1">MDNIPASNRRCEIDDGNLVRDRYNFRDTLIVDGLMMKGWYLLYCKRSEQERAVINLDRQGVECYYPQVRIDKIVRGKKQEVLEPLFPSYVFVYFDPEQVSYTSIRSTRGVADFIRRGSTPQLVQQELIYQLMMNEDCDEHKEALCELPKPGDSLTLSQGQFKGIDAIYQEADGEKRSFMLINLLGRAVTVSVDNKDLIKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWW5</accession>
    <name>D0YWW5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 11 15">6-phosphogluconate dehydrogenase, decarboxylating</fullName>
            <ecNumber evidence="6 11 15">1.1.1.44</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">VDA_001798</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 11">Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11 15">
            <text>6-phospho-D-gluconate + NADP(+) = CO2 + D-ribulose 5-phosphate + NADPH</text>
            <dbReference type="Rhea" id="RHEA:10116"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58759"/>
            <dbReference type="EC" id="1.1.1.44"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 11 15">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 3/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 11">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 11 15">Belongs to the 6-phosphogluconate dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.44" evidence="6 11 15"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298721.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001798"/>
    <dbReference type="EnsemblBacteria" id="EEZ40766">
        <property type="protein sequence ID" value="EEZ40766"/>
        <property type="gene ID" value="VDA_001798"/>
    </dbReference>
    <dbReference type="GeneID" id="57342091"/>
    <dbReference type="eggNOG" id="COG0362">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1245550at2"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00410"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004616">
        <property type="term" value="F:phosphogluconate dehydrogenase (decarboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019521">
        <property type="term" value="P:D-gluconate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016054">
        <property type="term" value="P:organic acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006114">
        <property type="entry name" value="6PGDH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006113">
        <property type="entry name" value="6PGDH_Gnd/GntZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006184">
        <property type="entry name" value="6PGdom_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006183">
        <property type="entry name" value="Pgluconate_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11811">
        <property type="entry name" value="PTHR11811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00393">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000109">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00076">
        <property type="entry name" value="6PGDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01350">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00873">
        <property type="entry name" value="gnd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00461">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 15" id="KW-0311">Gluconate utilization</keyword>
    <keyword evidence="11 15" id="KW-0521">NADP</keyword>
    <keyword evidence="8 11 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10 11 15" id="KW-0570">Pentose shunt</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6PGD" evidence="16">
        <location>
            <begin position="179"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="13">
        <location>
            <begin position="128"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="13">
        <location>
            <begin position="186"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="12">
        <location>
            <position position="183"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="12">
        <location>
            <position position="190"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="9"/>
            <end position="14"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="32"/>
            <end position="34"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="74"/>
            <end position="76"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="102"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="260"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="287"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="445"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="451"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00018193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR000109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000109-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR000109-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR000109-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM01350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EEZ40766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="482" mass="52664" checksum="816A970C85D5C367" modified="2010-01-19" version="1">MKGDIGVIGLAVMGQNLILNMNDHGFKVVAYNRTVSKVEEFLEGPAKGTNIIGATSLEDLVSKLESPRKIMLMVRAGSVVDAFIEQLVPLLDKGDIIIDGGNSNYPDTNRRVAELKEKGILYVGSGVSGGEEGARFGPSIMPGGSEAAWPAIKPIFQAISAKTEAGEACCDWVGKDGAGHFVKMVHNGIEYGDMQLISEAYHFMKSGLGLSHDEMQAIFQEWNKTELDSYLVEITAEILGYKDTDGQPLVEKILDTAGQKGTGKWTGINALDLGIPLTLITESVFARCVSSMKDQRVEAQALFGKTITPIEGDKKEWVDALRQALLASKIISYAQGFMLIREASEEFNWDLNYGNVALMWRGGCIIRSAFLGNIRDAYDANPEIKFLGSDPYFKDILQSSMAAWRKVAAKSLEVGLPMPTMTSGLTFLDSYTTADLPANMIQAQRDYFGAHTYERIDQPRGQFFHTNWTGTGGNTASTTYDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWZ8</accession>
    <name>D0YWZ8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ATP-dependent Clp protease proteolytic subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002051</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the peptidase S14 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299283.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002051"/>
    <dbReference type="EnsemblBacteria" id="EEZ41019">
        <property type="protein sequence ID" value="EEZ41019"/>
        <property type="gene ID" value="VDA_002051"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0740">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="724905at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001907">
        <property type="entry name" value="ClpP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023562">
        <property type="entry name" value="ClpP/TepA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10381">
        <property type="entry name" value="PTHR10381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00574">
        <property type="entry name" value="CLP_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00127">
        <property type="entry name" value="CLPPROTEASEP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="658" mass="71773" checksum="8701CBF41B4D397E" modified="2010-01-19" version="1">MAKKNKSWFTLTNQGDDQPVKVWIHGDIGSYEIAAIDLIKALQSIGSQDVHFRIQSYGGSVYEGLAMYNAIKAHKGKTVGIVDGLVASISSYFLMACDEVHMPENAKLMIHDPAIGAWGGEDELESALTQLKNAKQTIAEAYVERSGQSLDDVLEAMAKETWFTASQALEFGLIDQVIDAVDLSNCLKTVSSQELQNKAFKHTPADLLAQLSSPTPTNPIESEPMPKPNDDALINAVKKENERQSAIRALCAAHKVKNTLRDEMLNDLNCSTDDASIKILQYLGNLSLKGQDDPNTASDAGLTNSHIHVGNGNITKDTLQNALNARCGTAKIEKDNPYRLKTLLDMAEISVGKDAKYCSTKNELVARAFNSGDFSDIITESVRTVMRDEAEVRSPLWRELANTEDLPNFKETDLILINDAPDLMAISEDGEYKSATIKGSGEKIQLGSFGREIAFTRQAIINDEIALIAKIPRKFMQAAYRLSDKLMFNAILSGKMGDGKGVFQAGTANKWGNLVNDIPAADYQALVMALHKSFATTQTSEGDALDLRGEILLANPDHASFLEAVLNTASKPDSFNPAYKKFQKVVETARLSEVNGAIGLTGKDFDSVVMAFLDSAQDPWLETGDGWSSDGAKFRITYDVASKVIDRRGIAQALFANK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX40</accession>
    <name>D0YX40_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">TsgA protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_001908</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298914.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001908"/>
    <dbReference type="EnsemblBacteria" id="EEZ40876">
        <property type="protein sequence ID" value="EEZ40876"/>
        <property type="gene ID" value="VDA_001908"/>
    </dbReference>
    <dbReference type="GeneID" id="57341967"/>
    <dbReference type="eggNOG" id="COG0738">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1121832at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="51"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="76"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="98"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="134"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="163"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="206"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="249"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="273"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="297"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="331"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="360"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="6"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="395" mass="43681" checksum="E2487A3B976F20EF" modified="2010-01-19" version="1">MTNKNRNLLTWISFLSYALTGSLIIVTGIVMGDIAKYFDLPISSMSNTFTFLNTGILISIFLNVWLMEIVPLKRQLMFGFGLMVLAILGLMFGHNLALFSGCMFVLGVVSGITMSIGTYLITHIYEGKQRGSRLLFTDSFFSMAGMIFPVISTAVLAHHLEWYWVYAAIGVIYLAIFILALISTFPELGKKEDEQQAAPEKEKWGVGVLFLSIAALCYILGQLGFVSWIPEYATKQLGMTITDAGQLVSYFWGAYMIGMWIFSVLLKKFDLQRFVMVLSALATLLMYWFNTDTDAKTLLYVISALGFFSSAIYTSIITLGSQQTKAASPKLVNFILLCGTIGTMLTFVVTSPIVESFGTHAALMTANGLYAVVFLMCFLVGFVTKHRIHGHADAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXA3</accession>
    <name>D0YXA3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">High frequency lysogenization protein HflD homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">hflD</name>
        <name evidence="2" type="ORF">VDA_001643</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the HflD family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298430.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001643"/>
    <dbReference type="EnsemblBacteria" id="EEZ40616">
        <property type="protein sequence ID" value="EEZ40616"/>
        <property type="gene ID" value="VDA_001643"/>
    </dbReference>
    <dbReference type="GeneID" id="57342275"/>
    <dbReference type="eggNOG" id="COG2915">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="870739at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3890.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00695">
        <property type="entry name" value="HflD_protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007451">
        <property type="entry name" value="HflD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035932">
        <property type="entry name" value="HflD-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38100">
        <property type="entry name" value="PTHR38100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04356">
        <property type="entry name" value="DUF489"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101322">
        <property type="entry name" value="SSF101322"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="206" mass="22931" checksum="DF51463BEDF49617" modified="2010-01-19" version="1">MANTLYDRTIAFAGICQAVKLVQQVAQTGRCDNEMLTATLESILVTDPANTLAVYHSDEANLRIGLEALVKDIDNTSSGNELTRYLVGVMALERKLSGRRDSMAQLGDRIDLLKRQTEHFELLEEQMLSNIASVYLDIISPLGPRIQVSGTPAQLQIPQVQHKVRALLLAAIRSAVLWRQVGGKRRHLIFGRKQMVEQAKILLARC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXC8</accession>
    <name>D0YXC8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AsmA protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001668</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298482.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001668"/>
    <dbReference type="EnsemblBacteria" id="EEZ40641">
        <property type="protein sequence ID" value="EEZ40641"/>
        <property type="gene ID" value="VDA_001668"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2982">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1068066at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007844">
        <property type="entry name" value="AsmA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05170">
        <property type="entry name" value="AsmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AsmA" evidence="2">
        <location>
            <begin position="1"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="706" mass="76289" checksum="EDDCD1A8EB7BECD9" modified="2010-01-19" version="1">MKKFFYVVVALLLIIALGIGALLTLVNPNQFKPLISEQVKKATGRDLVIDGDISWRFFPTLGLTVGKTAFRNPNGFTEPDLMKFTDAELSVSVMPLFSHQLEIGKVILNGAHIFIETRKDGVSNLDGLGEASQSPSESSAHSEKSTKTQNDSATKSEQPWAISLAGIEVTNASATINNDQTDSATLLTNLNLNLDRFIPGQWSAMNFDLDGNTNGIGFSAKGKTSFNLSSNYKHIALKDVDFTASAESKTFHIPQLSLSLDHFDFGQWATIKYQTQGSIPNLKFASQGALRLNLDKALTKAEFEQIALTADLSGAMLPRPEMKIALNGDAQYLVAEKLASLSNLKLVVDEVTATGQLSYQTSTKPKLQFDLHSPDINVDKWLGMSSKQNATIAQTESKSSQASDVAKGSVSQTKVTEPNLSALKSFDLNGQLAVDKLHVANVNISDVKMQMSILNGVLNLKQLHAKLYGGTVDATAMVDANPQRAKYRFSPRIKGIQIQPLLKALADNDSLAGTANLDVSLSGQGLSEQSIRQHVYGSVTASINNGALYGVNLPEMIREAKAKLKGKAIDGANAEKKTDFSSLSAAITIKNGVASTSNLAAHSPLFNVSGSGNTNLVSEQIDFTVNALISDHKQANGQLVVPIEIKGNWDKPEYRLDLKQLLLKNNTLKQKAEKEINRGLEKIFGGEGKNEDLKNAADQLLKGLFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXE6</accession>
    <name>D0YXE6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Putative gluconeogenesis factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001625</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Required for morphogenesis under gluconeogenic growth conditions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the gluconeogenesis factor family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298397.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40598">
        <property type="protein sequence ID" value="EEZ40598"/>
        <property type="gene ID" value="VDA_001625"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0391">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="665169at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043743">
        <property type="term" value="F:LPPG:FO 2-phospho-L-lactate transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10680">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00973">
        <property type="entry name" value="Gluconeogen_factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002882">
        <property type="entry name" value="CofD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038136">
        <property type="entry name" value="CofD-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010119">
        <property type="entry name" value="Gluconeogen_factor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30135">
        <property type="entry name" value="PTHR30135"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01933">
        <property type="entry name" value="CofD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142338">
        <property type="entry name" value="SSF142338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01826">
        <property type="entry name" value="CofD_related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="297" mass="32278" checksum="F7168C6E715367E9" modified="2010-01-19" version="1">MVNTNTSNKKIVAIGGGHGLGRILSSLSDYGSQVTGIVATTDNGGSTGRIRACQGGIAWGDTRNCINQLITEPSVGSMIFEYRFRGNGELNGHNLGNLMLTALDNLSVRPLDAINLIRDMLKVSTHIIPMSEYPADLAAMTPSGEIICGETSVDELIEVPQRLYVDPAVPATKEAVVAIEQADLILLGPGSFLTSVMPSLLLKEIAQALKHTSARLVFITNLDKENGPAGQMDLVTMLHWCERSIGGRRIDIILSDKYYDELESGYHQHVSDLAASNHVWRHDRNKLKHAIKQLLIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXQ6</accession>
    <name>D0YXQ6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002069</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002069"/>
    <dbReference type="EnsemblBacteria" id="EEZ41037">
        <property type="protein sequence ID" value="EEZ41037"/>
        <property type="gene ID" value="VDA_002069"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5032TTG">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1347131at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="228" mass="26496" checksum="4BAB94A00A3FF574" modified="2010-01-19" version="1">MKQGQTGPYLCVGDNGNQYIVKGPNTTYRGLINEWVCGQLGKALGIPIPDFEIAYVDESLIEFGTYELTEGDWFASKYEENIQDVPFHLISKLDTEQLKLLFLFDYWIKNGDRNLTEYGGNPNLFICSDLCSFVVLDHNLAFDREHDQIFESLKRIHVASTAWFTEQKDLFDKEYYESRLEDAMKELDSILESVPEEWLDNCGDDSILKEIRTTLSRFRLPEFWEGIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXR4</accession>
    <name>D0YXR4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC-type multidrug transport system ATPase and permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_002077</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002077"/>
    <dbReference type="EnsemblBacteria" id="EEZ41045">
        <property type="protein sequence ID" value="EEZ41045"/>
        <property type="gene ID" value="VDA_002077"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1132">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="80"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="163"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="186"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="31"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="362"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="395"/>
            <end position="402"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ41045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="609" mass="68018" checksum="71B68D99B281CC70" modified="2010-01-19" version="1">MSHRTTTQMINWSWIITQAKKHKKRLITANIIAIIATLVSVPIPLLMPLMVDEVLLKKPGEGIVYLNHLLPDHWQGPTGYILMVLLLVVLMRVISQALNILQSRQFTLVAKDITYNLREHLLNKLGRISMRQYEERGSGGVTSHLITDVETIDKFVGDTLSRFLVGLLTVIGTAIVLLWINWKLGLLILLVNPIVVYASQLMGNRVKNLKRQENKSFEKFQQRLVETLDGLYQLRASNKEREFLARLKHDADDIRHSADKFAWQSEAAGRVSFLLFLIGFEVFRAAAMLMVVFSNLTVGEMLAVFGYLWFMLTPVQELLNIQFAWYGASAAMQRLNTLLTLDEEKRPQATVDPFTANQAIDIQLQDVHFSYDDEKKILNSLSLSIPAGKRVALVGASGGGKSTLIQLLLGIYQKNHGNILVNGHPIEAVSYEQLRKKMAVVLQHPVLFNDTLRHNLTLGGHFSDEQLWQALEIAQLTDVTERLTAGLDTEIGRQGIRLSGGQRQRLAIARMVLSSPDFVILDEATSALDTATEAALHHALNTFLNGKTTLIVAHRLSAVKQADLIYVLEDGQVTQAGTHDELVATDGLYQTLYGSSQSTNIEPVVVNAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXT9</accession>
    <name>D0YXT9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative fumarate and nitrate reduction regulatory protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_002102</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002102"/>
    <dbReference type="EnsemblBacteria" id="EEZ41070">
        <property type="protein sequence ID" value="EEZ41070"/>
        <property type="gene ID" value="VDA_002102"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0664">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012318">
        <property type="entry name" value="HTH_CRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018335">
        <property type="entry name" value="Tscrpt_reg_HTH_Crp-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13545">
        <property type="entry name" value="HTH_Crp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00034">
        <property type="entry name" value="HTHCRP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00419">
        <property type="entry name" value="HTH_CRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00042">
        <property type="entry name" value="HTH_CRP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51063">
        <property type="entry name" value="HTH_CRP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="2">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="HTH crp-type" evidence="3">
        <location>
            <begin position="123"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="210" mass="23801" checksum="8B5185D12D85DADA" modified="2010-01-19" version="1">MDQIIERKKPIQKGQELFKAGDELKSLYAIRSGTIKSYTITEQGDEQITAFHLAGDLVGFDAINEMQHPSFAQSLETSMVCEIPFEILDDLSGKMPKLRQQIMRLMSSEIKGDQEMILLLSKKNAEERLAAFLYNLSLRFSQRGFSPREFRLTMTRGDIGNYLGLTVETISRLLGRFQKSGMLSVKGKYITILDHEEMARLAGVSKNNNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXW7</accession>
    <name>D0YXW7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002130</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299505.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002130"/>
    <dbReference type="EnsemblBacteria" id="EEZ41098">
        <property type="protein sequence ID" value="EEZ41098"/>
        <property type="gene ID" value="VDA_002130"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1910">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="750230at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041657">
        <property type="entry name" value="HTH_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024370">
        <property type="entry name" value="PBP_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010093">
        <property type="entry name" value="SinI_DNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12728">
        <property type="entry name" value="HTH_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12727">
        <property type="entry name" value="PBP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01764">
        <property type="entry name" value="excise"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_17" evidence="2">
        <location>
            <begin position="10"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="PBP_domain" evidence="1">
        <location>
            <begin position="91"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="303" mass="33461" checksum="E71EDDBCF4B69EF1" modified="2010-01-19" version="1">MTEFPEFMNAKLVAEYLDLNEKKVYALANEGLLPATKVTGKWLFPKAMLDKWLLESCHNGVLNDRLLIAGSDDPLLQMVVGKMANQLGSTALIGYTSTGTRQGLSMLSKGHVDICAIHWGNAEEAALRHPALLQQYSGHKNWVLVHAFEREQGLVVSKEIADAVNNRSLNPHELVASRWRWALRQEGAGSMRALEEWLHGSACNLSMLTQVDVCNSERELASAIARGHADVGCASESTAGEFGLGFVPLCTEAFELVIPKNIYFRTLQQQLLQSLSDPEVQKRGHELGGYNFARTGKQVWSSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY37</accession>
    <name>D0YY37_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299637.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41168">
        <property type="protein sequence ID" value="EEZ41168"/>
        <property type="gene ID" value="VDA_002200"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5033PCR">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1404996at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="172"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="219" mass="25529" checksum="833BC4B13BF694E9" modified="2010-01-19" version="1">MDELAKAVQKKYIEDITKKYPLHRFLVMFMVIISSYIYSKGNDVRVLSELQNIKLSFLFDFNKGLLASVNFEQLVIAIFISGIIGYIYSKVSSMSFNLLTKLSSFDSYITQIREKVDSKKSQEEVLNYFLAKDISKELEGLRVKLKSFHTHSELFLVTALIIGWGFGSNNYFDWFLVLMFMVMIFINIWKAFQFYISDFLPYYITEQTLLGATVEFGDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYD3</accession>
    <name>D0YYD3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Malonyl-[acyl-carrier protein] O-methyltransferase</fullName>
            <shortName evidence="5">Malonyl-ACP O-methyltransferase</shortName>
            <ecNumber evidence="3 5">2.1.1.197</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Biotin synthesis protein BioC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">bioC</name>
        <name evidence="7" type="ORF">VDA_002296</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>malonyl-[ACP] + S-adenosyl-L-methionine = malonyl-[ACP] methyl ester + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:17105"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9954"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:78845"/>
            <dbReference type="EC" id="2.1.1.197"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Cofactor biosynthesis; biotin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the methyltransferase superfamily.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.197" evidence="3 5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299811.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002296"/>
    <dbReference type="EnsemblBacteria" id="EEZ41264">
        <property type="protein sequence ID" value="EEZ41264"/>
        <property type="gene ID" value="VDA_002296"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1664438at2"/>
    <dbReference type="UniPathway" id="UPA00078"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010340">
        <property type="term" value="F:carboxyl-O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102130">
        <property type="term" value="F:malonyl-CoA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009102">
        <property type="term" value="P:biotin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00835">
        <property type="entry name" value="BioC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011814">
        <property type="entry name" value="BioC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02072">
        <property type="entry name" value="BioC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0093">Biotin biosynthesis</keyword>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="6">
        <location>
            <begin position="77"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="288" mass="32003" checksum="ADF47C9E56E09A28" modified="2010-01-19" version="1">MSDVIKNTSDYNETLFNKDLIEKAFSKAASNYDQAAAFQRQVGHRLLDKIDMALIGANTVNTSAVDTSTNKATKIILDVGCGTGYFSQQLQGLDAQVTALDLSNKMLEQTKRRCAESVVCVQGDAENLPFTANQFDIGFSNLALQWCDDLSQPLRQLQRVVKPGGKIYFTTLVDGSLFELIDAWKQVDQYQHVNDFLTEREVKLALAQSGVKTHHLEFLPITINYHKAIELMRDLKGIGATHIPNGRNTGLIRKSALHKLELAYQAFQNSQGLLPATYQVCFGVITND</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYE4</accession>
    <name>D0YYE4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">7-carboxy-7-deazaguanine synthase</fullName>
            <shortName evidence="5">CDG synthase</shortName>
            <ecNumber evidence="5">4.3.99.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Queuosine biosynthesis protein QueE</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">queE</name>
        <name evidence="7" type="ORF">VDA_002307</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>6-carboxy-5,6,7,8-tetrahydropterin + H(+) = 7-carboxy-7-deazaguanine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:27974"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:61032"/>
            <dbReference type="ChEBI" id="CHEBI:61036"/>
            <dbReference type="EC" id="4.3.99.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </cofactor>
        <text evidence="5">Binds 1 S-adenosyl-L-methionine per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="5">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Purine metabolism; 7-cyano-7-deazaguanine biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="4.3.99.3" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299831.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002307"/>
    <dbReference type="EnsemblBacteria" id="EEZ41275">
        <property type="protein sequence ID" value="EEZ41275"/>
        <property type="gene ID" value="VDA_002307"/>
    </dbReference>
    <dbReference type="GeneID" id="57341509"/>
    <dbReference type="eggNOG" id="COG0602">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1141206at2"/>
    <dbReference type="UniPathway" id="UPA00391"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016840">
        <property type="term" value="F:carbon-nitrogen lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904047">
        <property type="term" value="F:S-adenosyl-L-methionine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:queuosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00917">
        <property type="entry name" value="QueE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024924">
        <property type="entry name" value="7-CO-7-deazaguanine_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027609">
        <property type="entry name" value="rSAM_QueE_Proteobac"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000370">
        <property type="entry name" value="QueE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04322">
        <property type="entry name" value="rSAM_QueE_Ecoli"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3 5" id="KW-0408">Iron</keyword>
    <keyword evidence="4 5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="6">
        <location>
            <begin position="17"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="11"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="5">
        <location>
            <begin position="36"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="5">
        <location>
            <begin position="135"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="26"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="37"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="222" mass="24579" checksum="5A0518221C3E443D" modified="2010-01-19" version="1">MYKLNEVFETIQGEGVFTGVPAIFVRLQICPVGCSWCDTKQTWSAEPQDFTTLDRIMAKTGDSPLWTEIDAQGIVSLLQDQGYTAKHVVITGGEPCIYDLRPLTQALEASGYQCQIETSGTSEVQATEATWVTVSPKINMKGKLPVLEKALSRANEIKHPVGTQKDLDQLDELLNGVALRSDVTIALQPISQKPRATELCIETCIKRNWRLSIQTHKYLAIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYI5</accession>
    <name>D0YYI5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Acetolactate synthase catabolic</fullName>
            <ecNumber evidence="6">2.2.1.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_002348</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the TPP enzyme family.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.6" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299930.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002348"/>
    <dbReference type="EnsemblBacteria" id="EEZ41316">
        <property type="protein sequence ID" value="EEZ41316"/>
        <property type="gene ID" value="VDA_002348"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="391134at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003984">
        <property type="term" value="F:acetolactate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034077">
        <property type="term" value="P:butanediol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012782">
        <property type="entry name" value="Acetolactate_synth_catblc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012000">
        <property type="entry name" value="Thiamin_PyroP_enz_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012001">
        <property type="entry name" value="Thiamin_PyroP_enz_TPP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000399">
        <property type="entry name" value="TPP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045229">
        <property type="entry name" value="TPP_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme-bd_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18968">
        <property type="entry name" value="PTHR18968"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00205">
        <property type="entry name" value="TPP_enzyme_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02776">
        <property type="entry name" value="TPP_enzyme_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02418">
        <property type="entry name" value="acolac_catab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00187">
        <property type="entry name" value="TPP_ENZYMES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TPP_enzyme_N" evidence="5">
        <location>
            <begin position="7"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_M" evidence="3">
        <location>
            <begin position="192"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_C" evidence="4">
        <location>
            <begin position="388"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="554" mass="60075" checksum="B0D6A4AA1383B4D0" modified="2010-01-19" version="1">MSDKTVSGAELVVETLNAHKVPHIFGIPGAKVDAVFEAVCDNGPEIIICHHEQNAAFMAAATGRLTGKAGVCLATSGPGASNLVTGVATANSEGDPVVALAGAVPLSMYSHNTHQSMDTRSLFNPITKFSAEILDTGSVPDVVHKAFRIAEKPTQGASFVSLPQDILTNRIDALNVQNPNPILFGGANKQAIREAADKINSAKNPVLLLGMDASQPLVTEAIRSLLKQTPIAVVNTFAAAGVISHDLYNCFLGRVGLFKNQPGDIALNSADLIITVGYDPIEYDPILWNKDAQTPIVHIGYQQADLEVSYNPICEVVGDLASSIADLAVELDLRESLENNQQIQLLRHDLQRIMMLGENKVSTHGVHPLRFIHDLRRFVSDDTTVCCDVGSIYIWMARYFHSFEPRRLLFSNGQQTLGVALPWAIAASLLHPNEKVISMSGDGGFLFSSMELATAVRHNCNIVHFVWTDHSYDMVKIQQLKKYGRESAVSFTGPDIVKYAESFGAHGLAINCADDIAPVLRKAMSLSGPVLVNVNIDYSDNSRLLDQMYPCHQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-12-02" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYK1</accession>
    <name>D0YYK1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002364</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002364"/>
    <dbReference type="EnsemblBacteria" id="EEZ41332">
        <property type="protein sequence ID" value="EEZ41332"/>
        <property type="gene ID" value="VDA_002364"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502ZC5D">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043724">
        <property type="entry name" value="DUF5666"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18914">
        <property type="entry name" value="DUF5666"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5666" evidence="1">
        <location>
            <begin position="23"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5666" evidence="1">
        <location>
            <begin position="93"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5666" evidence="1">
        <location>
            <begin position="169"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="234" mass="26183" checksum="EDCBB121220E6B74" modified="2010-01-19" version="1">MGYKVLSVIEVENTDLAGKYELEGTLSQLDSVASTFKLGQVVVDYANIQLDPTIGNGDWVEVTGEMIDGAFVATEVEVDNYDDNEDFDDAEIEGVVTWINNEKTLFTLNARGQFVINNSTRFEDGTRNNLKMGTLVEVTAINGVAKEIEFERDHDGDHDQGTWREFDVEGIVSDVTDSTITLYGVQQPVYVDNMTRYEDRLTLATLPGKRVEIEGIVRNGQKIAREIELEELDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYK8</accession>
    <name>D0YYK8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ubiquinone biosynthesis O-methyltransferase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">2-polyprenyl-6-hydroxyphenol methylase</fullName>
            <ecNumber evidence="1">2.1.1.222</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">3-demethylubiquinone 3-O-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.64</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ubiG</name>
        <name evidence="2" type="ORF">VDA_002371</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 3-(all-trans-polyprenyl)benzene-1,2-diol + S-adenosyl-L-methionine = a 2-methoxy-6-(all-trans-polyprenyl)phenol + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:31411"/>
            <dbReference type="Rhea" id="RHEA-COMP:9550"/>
            <dbReference type="Rhea" id="RHEA-COMP:9551"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:62729"/>
            <dbReference type="ChEBI" id="CHEBI:62731"/>
            <dbReference type="EC" id="2.1.1.222"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 3-demethylubiquinol + S-adenosyl-L-methionine = a ubiquinol + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:44380"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="Rhea" id="RHEA-COMP:10914"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:84422"/>
            <dbReference type="EC" id="2.1.1.64"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. UbiG/COQ3 family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.222" evidence="1"/>
    <dbReference type="EC" id="2.1.1.64" evidence="1"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299976.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002371"/>
    <dbReference type="EnsemblBacteria" id="EEZ41339">
        <property type="protein sequence ID" value="EEZ41339"/>
        <property type="gene ID" value="VDA_002371"/>
    </dbReference>
    <dbReference type="GeneID" id="57341429"/>
    <dbReference type="eggNOG" id="COG2227">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1515497at2"/>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102208">
        <property type="term" value="F:2-polyprenyl-6-hydroxyphenol methylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008425">
        <property type="term" value="F:2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008689">
        <property type="term" value="F:3-demethylubiquinone-9 3-O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00472">
        <property type="entry name" value="UbiG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010233">
        <property type="entry name" value="UbiG_MeTrfase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01983">
        <property type="entry name" value="UbiG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="1 2" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0830">Ubiquinone</keyword>
    <keyword evidence="1" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="236" mass="26257" checksum="D6962328488638E0" modified="2010-01-19" version="1">MTKQLNVDPAEISKFEDMASRWWDPEGEFKPLHQINPLRLNFVIDKADGLFGKKVLDVGCGGGILAESMAVEGADVTGLDMGKEPLTVARLHALETGVKLEYVQATAEEHAEENPQAYDVVTCMEMLEHVPDPASVIAACAKMVKPGGHVFFSTLNRNIKSYLFAIVGAEHLLKIVPKGTHHHEKFIRPSEMMAMIDRTELQDKHITGLHYNPLTNTYRLGTNVDVNYIVHTIKQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYM7</accession>
    <name>D0YYM7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative metal-dependent phosphoesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002390</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300013.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002390"/>
    <dbReference type="EnsemblBacteria" id="EEZ41358">
        <property type="protein sequence ID" value="EEZ41358"/>
        <property type="gene ID" value="VDA_002390"/>
    </dbReference>
    <dbReference type="GeneID" id="57341409"/>
    <dbReference type="eggNOG" id="COG0613">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1309717at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004013">
        <property type="entry name" value="PHP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003141">
        <property type="entry name" value="Pol/His_phosphatase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016195">
        <property type="entry name" value="Pol/histidinol_Pase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02811">
        <property type="entry name" value="PHP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00481">
        <property type="entry name" value="POLIIIAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89550">
        <property type="entry name" value="SSF89550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="POLIIIAc" evidence="1">
        <location>
            <begin position="3"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="289" mass="32628" checksum="E183C59C9E3A8585" modified="2010-01-19" version="1">MLFDLHTHTTASDGRLTPEELVKRAVERRVDVLAITDHDTVAALPIAQDVIDQQNLPITLINGIEISTVWQNFDIHIVGLNIDPMHPAMTQLIAEQAERRHKRAQEIGERLAKNRIEGAFEGASQLANGETITRAHFAQWLVEQEHAKTMQAVFKKFLTRGNPGYVPPNWCTIAEAVTAIHASGGKAVIAHPGRYKMTAKWLKRLIACFIEAKGDAIEVAQPQQGPQERRTLGDYAITYHLLASQGSDFHYQSPWTELGRNLWLPKDVVPIWHDWTVEKKREDVEQPHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYM8</accession>
    <name>D0YYM8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">2-keto-3-deoxy-D-arabino-heptulosonate-7-phosphate synthase I beta</fullName>
            <ecNumber evidence="3">2.5.1.54</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002391</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.5.1.54" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300014.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002391"/>
    <dbReference type="EnsemblBacteria" id="EEZ41359">
        <property type="protein sequence ID" value="EEZ41359"/>
        <property type="gene ID" value="VDA_002391"/>
    </dbReference>
    <dbReference type="GeneID" id="57341408"/>
    <dbReference type="eggNOG" id="COG2876">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="687380at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003849">
        <property type="term" value="F:3-deoxy-7-phosphoheptulonate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016832">
        <property type="term" value="F:aldehyde-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006218">
        <property type="entry name" value="DAHP1/KDSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041071">
        <property type="entry name" value="DAHP_snth_FXD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006268">
        <property type="entry name" value="DAHP_syn_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18152">
        <property type="entry name" value="DAHP_snth_FXD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00793">
        <property type="entry name" value="DAHP_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01361">
        <property type="entry name" value="DAHP_synth_Bsub"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAHP_snth_FXD" evidence="2">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="DAHP_synth_1" evidence="1">
        <location>
            <begin position="87"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="337" mass="36575" checksum="313D061C850CEA0F" modified="2010-01-19" version="1">MIIVLKPQATEKQAKELLAKIESAGLKPLYMPGVERIVLGALGDERKLQTMNFEAYPFVENVKPILTKYKMVSREVQAHDTQVRFGNAVIGGDKFAVIAGPCSVESEQQLLSVAEMVKQYGAIALRGGAYKPRTSPYDFQGLGETGLQLLQQANQQLGLPTVSEVMDISQLDIMCQYVDCLQIGARNMQNYGLLKAVGESGKPVLLKRGLAATIEELLLAAEYIYDAGNPNIILCERGIRTFETATRNTLDLNAVAYLKQRSHLPVVVDPSHGTGVRELVIPLSRAAVAVGADGIIVETHLNPCQALSDGHQALTGPMFAQLMDEITPFVEAAGRTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYN7</accession>
    <name>D0YYN7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_002400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300023.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002400"/>
    <dbReference type="EnsemblBacteria" id="EEZ41368">
        <property type="protein sequence ID" value="EEZ41368"/>
        <property type="gene ID" value="VDA_002400"/>
    </dbReference>
    <dbReference type="GeneID" id="57341397"/>
    <dbReference type="eggNOG" id="COG1092">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="468283at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019614">
        <property type="entry name" value="SAM-dep_methyl-trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10672">
        <property type="entry name" value="Methyltrans_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltrans_SAM" evidence="4">
        <location>
            <begin position="25"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="312" mass="35090" checksum="E72BDDEB307E54A0" modified="2010-01-19" version="1">METSALPSLEAHLLSSLATPPSEVRRLFHGRGRCWQGLEQITVDYLQGQVLVSLFKEPEPEFLQGLYAMLENLVSQPQWQQSGATSLLLQHRDRQGSPLEVIWGDLREYQDVIESGLTYKLDLGRNQNNGLFLDMRYGRDWVREQANGKRVLNLFAYTCGFSVAAIAGGAEHVVNLDMAKSALSRGRDNHHLNQHDLKKVSFLGHELFKSWGKVRKLGPYDLIIIDPPSFQKGSFALTKDYQKILRRLPELLTEKGTVLACVNDPSISSQFLIDGMAQEAPSLQFIERLDNPPEFKDIDPEGGLKALVFKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYX1</accession>
    <name>D0YYX1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hypothetical starvation-inducible outer membrane lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002484</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300180.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002484"/>
    <dbReference type="EnsemblBacteria" id="EEZ41452">
        <property type="protein sequence ID" value="EEZ41452"/>
        <property type="gene ID" value="VDA_002484"/>
    </dbReference>
    <dbReference type="GeneID" id="57341294"/>
    <dbReference type="eggNOG" id="COG3065">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1751057at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019867">
        <property type="term" value="C:outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004658">
        <property type="entry name" value="OMP_Slp"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37530">
        <property type="entry name" value="PTHR37530"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03843">
        <property type="entry name" value="Slp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004982">
        <property type="entry name" value="SlP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00752">
        <property type="entry name" value="slp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018743" evidence="1">
        <location>
            <begin position="20"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="185" mass="20843" checksum="DBAF97A6D5C1C2C7" modified="2010-01-19" version="1">MYRTLFLGGILLFMVGCSAVPESLQTASDKPITNVQSLIATPELMQGQEVRLGGVIASIKNEENQTRLEISAMPLTSDGRPVLGAKPQGRFIAYENGFLEPMEYAPGRLVSVVGHFRGMEKGKVGEFDYNFPVIDATGDQIWQVHQEVRIDDVYPPCFGRYCHRYWRNYPYRGPMRGQVIQRVTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYY2</accession>
    <name>D0YYY2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">High-affinity zinc uptake system protein ZnuA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_002495</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the high-affinity zinc uptake transport system.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the bacterial solute-binding protein 9 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300199.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002495"/>
    <dbReference type="EnsemblBacteria" id="EEZ41463">
        <property type="protein sequence ID" value="EEZ41463"/>
        <property type="gene ID" value="VDA_002495"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4531">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1703187at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006829">
        <property type="term" value="P:zinc ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01019">
        <property type="entry name" value="ZnuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006128">
        <property type="entry name" value="Lipoprotein_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035520">
        <property type="entry name" value="ZnuA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006127">
        <property type="entry name" value="ZnuA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01297">
        <property type="entry name" value="ZnuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00690">
        <property type="entry name" value="ADHESNFAMILY"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0732">Signal</keyword>
    <keyword evidence="4 7" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018697" description="High-affinity zinc uptake system protein ZnuA" evidence="9">
        <location>
            <begin position="22"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="114"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ41463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="311" mass="34655" checksum="8BA455802159EF80" modified="2010-01-19" version="1">MRRLLSFCGASAMLFSSLATAHELNVVTTVQPLNLIVSELTEGVAHSEAILPAGTSPHDYALRPSDVKKIKNADLVIWIGPQLESFLKKVLQGNSKNLALTEQAGIDFRHYGEEDEDHDHHHDDGMENAEHDHHDHDHHHEGIDPHVWLGPKQAIEVAKVITQQLVKQDPLHKEQYEANLSRFTSEVNQTITQLTTELKPLTGHGYYVFHDGYGYFEEQFGLKNLGHFTVEPDRRPGAKTLISIRQALQDHQAYCVFSEPQFSPAVVDSVVNGTEVKVGTLDPMATGIVAGKGGYVRFLQQLGQSFTKCLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ74</accession>
    <name>D0YZ74_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RNA polymerase sigma factor FliA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">RNA polymerase sigma factor for flagellar operon</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Sigma F</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Sigma-28</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">fliA</name>
        <name evidence="7" type="ORF">VDA_002587</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the sigma-70 factor family. FliA subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300404.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002587"/>
    <dbReference type="EnsemblBacteria" id="EEZ41555">
        <property type="protein sequence ID" value="EEZ41555"/>
        <property type="gene ID" value="VDA_002587"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1191">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1857862at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00962">
        <property type="entry name" value="Sigma70_FliA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000943">
        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007624">
        <property type="entry name" value="RNA_pol_sigma70_r3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012845">
        <property type="entry name" value="RNA_pol_sigma_FliA_WhiG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028617">
        <property type="entry name" value="Sigma70_FliA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04539">
        <property type="entry name" value="Sigma70_r3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000770">
        <property type="entry name" value="RNA_pol_sigma-SigE/K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00046">
        <property type="entry name" value="SIGMA70FCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02479">
        <property type="entry name" value="FliA_WhiG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00716">
        <property type="entry name" value="SIGMA70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0966">Cell projection</keyword>
    <keyword evidence="7" id="KW-0969">Cilium</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0282">Flagellum</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="4 5" id="KW-0804">Transcription</keyword>
    <keyword evidence="1 5" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RNA_pol_sigma70" evidence="6">
        <location>
            <begin position="205"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="5">
        <location>
            <begin position="206"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Sigma-70 factor domain-2" evidence="5">
        <location>
            <begin position="17"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Sigma-70 factor domain-3" evidence="5">
        <location>
            <begin position="97"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Sigma-70 factor domain-4" evidence="5">
        <location>
            <begin position="184"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Interaction with polymerase core subunit RpoC" evidence="5">
        <location>
            <begin position="44"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="240" mass="27144" checksum="770902F089CC3477" modified="2010-01-19" version="1">MNRALTYGRYQESPQAFIARHSSLVKRIAHHLMARLPPNILIEDLIQAGMIGLLEAQQNYDPTKGASFETFAGIRIRGAMLDDIRRGDWVPRSVYKNSRRISEAMAQLEHELGRDPNDHEVAEHLEMSLEQYHQALNDVNCGRLVGIDDLGISEDAVANDELLEENLPFQGVVDDSFRQALAEAIKTLPEREALVLSLYYDEELNLKEIGAVIGVSESRICQIHTQAMQRLKAKLKAWQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ79</accession>
    <name>D0YZ79_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Flagellar biosynthetic protein FliR</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">VDA_002592</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">Role in flagellar biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Bacterial flagellum basal body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the FliR/MopE/SpaR family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300418.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002592"/>
    <dbReference type="EnsemblBacteria" id="EEZ41560">
        <property type="protein sequence ID" value="EEZ41560"/>
        <property type="gene ID" value="VDA_002592"/>
    </dbReference>
    <dbReference type="GeneID" id="57341166"/>
    <dbReference type="eggNOG" id="COG1684">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1942709at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044780">
        <property type="term" value="P:bacterial-type flagellum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006303">
        <property type="entry name" value="FliR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002010">
        <property type="entry name" value="T3SS_IM_R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30065">
        <property type="entry name" value="PTHR30065"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01311">
        <property type="entry name" value="Bac_export_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00953">
        <property type="entry name" value="TYPE3IMRPROT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01400">
        <property type="entry name" value="fliR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="5 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0966">Cell projection</keyword>
    <keyword evidence="11" id="KW-0969">Cilium</keyword>
    <keyword evidence="11" id="KW-0282">Flagellum</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="41"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="127"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="183"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="214"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ41560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="260" mass="29051" checksum="58955410C3186DBB" modified="2010-01-19" version="1">MHYTSAILLDWLANYMWAFIRISSMMMTMTFFGARFVSAKIRLYLALTITFAVVPVLPQVPQDIALLSLHGFIITTQQIVIGAAIGLVTQFITQSFVLLGQILAMQSSLGFASMVDPANGQNTPVLGQLYLFLAIILFLMTDGHLEMLELIVKSFTTLPIGKAMFNGQDYYQLALWFGHMFKMALSMALAGIIALLTVNLSFGVMTRAAPQLNIFSLGFSFALLIGFVISWFVVRGLLPHYEQYWQFGLDKMCDLVRLNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZE1</accession>
    <name>D0YZE1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002654</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300614.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002654"/>
    <dbReference type="EnsemblBacteria" id="EEZ41622">
        <property type="protein sequence ID" value="EEZ41622"/>
        <property type="gene ID" value="VDA_002654"/>
    </dbReference>
    <dbReference type="GeneID" id="57341080"/>
    <dbReference type="eggNOG" id="COG2991">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007495">
        <property type="entry name" value="NqrM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40691">
        <property type="entry name" value="PTHR40691"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04400">
        <property type="entry name" value="NqrM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="73" mass="8010" checksum="2F033494DC9D67EA" modified="2010-01-19" version="1">MAVYLTTFAVFLLVIVAMAVGYIFQRKTVSGSCGGLGSVGIDKECDCPEPCDARKKREARAARQAEWKKNQII</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZG2</accession>
    <name>D0YZG2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002675</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300675.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41643">
        <property type="protein sequence ID" value="EEZ41643"/>
        <property type="gene ID" value="VDA_002675"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502ZBSU">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="62658at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019903" evidence="1">
        <location>
            <begin position="19"/>
            <end position="695"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="695" mass="79963" checksum="2F38FD0A54877222" modified="2010-01-19" version="1">MKKLILGIGLLVASCVVAKSTPSTLTAWVLTGSWQHPDSQHSPFTTIDSVRKWEATQTDMVFGSLQDLTANKNTVAIGYMYAHKFDCRPDEQLGWIADRAYQQDIPLETAFLHYQQDTIVALPDLSSGLHYLLQGEPLLSLYVHQQNYATARLPLQIQVNDQLITHFAYPITSLLVTASKPPRISIPILDEDSAIKEWREITIQWQQTDQGWLAQLSRPFSLLNNRPVYRGRSLNTGDKSLQAGFRPWSLQLTWSEPTQVERIATEPWLELDSYDDQTVMVFPGWDPANDRDSDGYIDSKEWQQRANKKASARFPHQARLIPTGKMWSGSCWYRTNFSDAKFNQLHASWYQFDWQRQGLSGAYNDDMAKLLGKNQFTLFQGGLIREMVPLIAGELDAEQKYGQQLAQFFTEIKHQTKTQYLAANISELNLWQYQAWPQELKQVVNVWLREHYLYPAIGLAQLQHYWEHFALMAQGDISLVMSSTKTGLSQQYPSQQQAWQQDITTGLALYYLFNVPQQTYYHSWNQTFVYGSGNTKFNPQNPVSSTWYQSGVPKNWAYYPQHMLAVDIGEPTLPPDGYRLVKWVSEKAKANSQDTQLGTIPIYPSHWFWLKRDGWWDDIPKEGVIARQYSKGLVLYRASREAKQSSFYQVEPINIELPELYQRVNFDGTLSPASQQISIKGYEGIVLKRYDGTEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZH8</accession>
    <name>D0YZH8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative p-aminobenzoyl-glutamate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002691</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300711.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41659">
        <property type="protein sequence ID" value="EEZ41659"/>
        <property type="gene ID" value="VDA_002691"/>
    </dbReference>
    <dbReference type="GeneID" id="57341038"/>
    <dbReference type="eggNOG" id="COG2978">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="350103at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015558">
        <property type="term" value="F:secondary active p-aminobenzoyl-glutamate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902604">
        <property type="term" value="P:p-aminobenzoyl-glutamate transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004697">
        <property type="entry name" value="AbgT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30282">
        <property type="entry name" value="PTHR30282"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03806">
        <property type="entry name" value="ABG_transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="172"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="212"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="270"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="310"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="350"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="392"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="419"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="449"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="480"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="520" mass="55186" checksum="3FAE7312527A49AD" modified="2010-01-19" version="1">MSNQAVKQAPEAPSSAMDKFLNGIERVGNKIPDPALLFFWGLVLVWVLSAVLSQFDFGLVHPVTQQSVEIKNLLTGESMASFLANMVKNFTGFAPLGIVLVAMLGVGVAEASGFINTGLKKMLNVTPVKFLTPMLILVAIVSHTAADAGYVLVIPLGGIIFHAAGRHPLAGIAAAFAGVSGGFSANFIPSGIDPLLAGFTQEAARIMDPDYIVNPLANIIFTGLSSFIIVAIGWYITDKIIEPRLAKTAIDDDAEEAPDMGSFTELESKAFSRAGWAMVAGIALLVAVLIPETSPLRSPSGEIAAFNAPVMQSIVPLIFILFVIPGIIYGKVAGTFKESQDVIKAMSTTMAGMAGFMVMVFFIAQFLVAFTQSNIGTLLALSGAKLLQEMNLPGQITIIGMILLTASVNLLVGSASAKWALIGPIMVPMLMAVGISPELTQAAYRVGDSVSNIISPMMVFFPLVVVYMQRYVKSSGIGTLASMMMPYSIAMLVGWTIFLLVYWAIGIPLGVQAPYTYTIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZT2</accession>
    <name>D0YZT2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Histidine decarboxylase</fullName>
            <shortName evidence="4">HDC</shortName>
            <ecNumber evidence="4">4.1.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">hdc</name>
        <name evidence="7" type="ORF">VDA_002795</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>H(+) + L-histidine = CO2 + histamine</text>
            <dbReference type="Rhea" id="RHEA:20840"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
            <dbReference type="ChEBI" id="CHEBI:58432"/>
            <dbReference type="EC" id="4.1.1.22"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 4 5 6">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 6">Belongs to the group II decarboxylase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.22" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301029.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002795"/>
    <dbReference type="EnsemblBacteria" id="EEZ41763">
        <property type="protein sequence ID" value="EEZ41763"/>
        <property type="gene ID" value="VDA_002795"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0076">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1478871at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004398">
        <property type="term" value="F:histidine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00609">
        <property type="entry name" value="Pyridoxal_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023523">
        <property type="entry name" value="Hist_deCOase_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002129">
        <property type="entry name" value="PyrdxlP-dep_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021115">
        <property type="entry name" value="Pyridoxal-P_BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00282">
        <property type="entry name" value="Pyridoxal_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00392">
        <property type="entry name" value="DDC_GAD_HDC_YDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="3 4 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 5 6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="4">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="4 5">
        <location>
            <position position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602129-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="378" mass="42965" checksum="3791FC1D61E8B70B" modified="2010-01-19" version="1">MTLSIENQNKLDVFWAHCVKNQYFNIGYPESADFNYTNLERFLRFSINNCGDWSEYCNYLLNSFDFEKEVIEYFAHTFKIPFDKCWGYVTNGGTEGNMFGCYLARELFPDSTLYYSKDTHYSVAKIVKLLRIKSQVVESLPNGEVNYDDLIKKIEQDGEKHPIIFANIGTTVKGAIDNIFEIQDRIAKLGIAREDYYIHADAALSGMILPFVDEPQGFNFADGIDSIGVSGHKMIGSPIPCGIVIAKKENVDQITVEIDYIAAHDKTITGSRNGHTPLMMWEAVKSHSFDEWQQRINRCLELAEYAVQQFQKAGIDAWRNKNSITVVFPCPSEDVWKKHCLATSNGLAHMVVSAHHLTHESIDDLINDVIADETRKIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZX6</accession>
    <name>D0YZX6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosomal RNA large subunit methyltransferase E</fullName>
            <ecNumber evidence="4">2.1.1.166</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">23S rRNA Um2552 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">rRNA (uridine-2'-O-)-methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rlmE</name>
        <name evidence="4" type="synonym">ftsJ</name>
        <name evidence="4" type="synonym">rrmJ</name>
        <name evidence="7" type="ORF">VDA_002839</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>S-adenosyl-L-methionine + uridine(2552) in 23S rRNA = 2'-O-methyluridine(2552) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42720"/>
            <dbReference type="Rhea" id="RHEA-COMP:10202"/>
            <dbReference type="Rhea" id="RHEA-COMP:10203"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74478"/>
            <dbReference type="EC" id="2.1.1.166"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.166" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301162.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002839"/>
    <dbReference type="EnsemblBacteria" id="EEZ41807">
        <property type="protein sequence ID" value="EEZ41807"/>
        <property type="gene ID" value="VDA_002839"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0293">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1798571at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008650">
        <property type="term" value="F:rRNA (uridine-2'-O-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01547">
        <property type="entry name" value="RNA_methyltr_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002877">
        <property type="entry name" value="RNA_MeTrfase_FtsJ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015507">
        <property type="entry name" value="rRNA-MeTfrase_E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01728">
        <property type="entry name" value="FtsJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005461">
        <property type="entry name" value="23S_rRNA_mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="3 4 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FtsJ" evidence="6">
        <location>
            <begin position="31"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4 5">
        <location>
            <position position="164"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR005461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="209" mass="23236" checksum="FF262C81643CEA6A" modified="2010-01-19" version="1">MSKKKHSGSSGRWLKEHFDDKYVLEAQKKGYRSRALFKIEEIQQKDKLLKPGMTVVDLGAAPGGWSQYAAGVVGDDGQVIACDILPMDPLPGVSFLQGDFREEAVLDALLERIQPDMVDVVLSDMAPNMSGNLASDQPRAMYLVELALDMCRQVLAPNGSFAVKVFQGEGFDQYLADIRSMFKVVKIRKPDSSRDRSREVYIVATGYKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZY3</accession>
    <name>D0YZY3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">Carbamoyl-phosphate synthase small chain</fullName>
            <ecNumber evidence="6">6.3.5.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5 6">Carbamoyl-phosphate synthetase glutamine chain</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">carA</name>
        <name evidence="8" type="ORF">VDA_002846</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>2 ATP + H2O + hydrogencarbonate + L-glutamine = 2 ADP + carbamoyl phosphate + 2 H(+) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:18633"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 6">Amino-acid biosynthesis; L-arginine biosynthesis; carbamoyl phosphate from bicarbonate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 1/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the CarA family.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.5" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301180.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002846"/>
    <dbReference type="EnsemblBacteria" id="EEZ41814">
        <property type="protein sequence ID" value="EEZ41814"/>
        <property type="gene ID" value="VDA_002846"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0505">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="662268at2"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00171"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004088">
        <property type="term" value="F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01744">
        <property type="entry name" value="GATase1_CPSase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01209">
        <property type="entry name" value="CPSase_S_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006274">
        <property type="entry name" value="CarbamoylP_synth_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002474">
        <property type="entry name" value="CarbamoylP_synth_ssu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036480">
        <property type="entry name" value="CarbP_synth_ssu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035686">
        <property type="entry name" value="CPSase_GATase1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00988">
        <property type="entry name" value="CPSase_sm_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01097">
        <property type="entry name" value="CPSase_sm_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52021">
        <property type="entry name" value="SSF52021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01368">
        <property type="entry name" value="CPSaseIIsmall"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="6 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CPSase_sm_chain" evidence="7">
        <location>
            <begin position="3"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="CPSase" evidence="6">
        <location>
            <begin position="1"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="6">
        <location>
            <position position="269"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="353"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00030197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ41814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="379" mass="40906" checksum="1B00BF2CAB29462C" modified="2010-01-19" version="1">MSKSALLVLEDGTVFHGMSIGADGSAVGEVVFNTSMTGYQEILTDPSYSQQIVTLTYPHIGNTGTNSEDEESTSIHAQGLVIRDLPLIASNFRNQLSLSDYLKSQNIVGIAEIDTRKLTRILREKGAQNGCIVAGNSLDEAFAQAQAQGFPGLSGMDLAKEVTTPETYSWKQGSWTLENGLPQDLDDCELPYHVVAYDFGAKRNILRMLVDRGCRLTVVPAQTSAEEVLALNPDGVFLSNGPGDPAPCDYAIAATKVFLDKNLPVFGICLGHQILALASGAKTVKMKFGHHGANHPVKDLDRDVVMITSQNHGFAVDEATLPETLRATHKSLFDGSLQGIHRTDKPAFSFQGHPEASPGPHDAAPLFDHFIELIKKHTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z012</accession>
    <name>D0Z012_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002875</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301258.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002875"/>
    <dbReference type="EnsemblBacteria" id="EEZ41843">
        <property type="protein sequence ID" value="EEZ41843"/>
        <property type="gene ID" value="VDA_002875"/>
    </dbReference>
    <dbReference type="GeneID" id="57340835"/>
    <dbReference type="eggNOG" id="ENOG5033D3F">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021932">
        <property type="entry name" value="DUF3545"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12065">
        <property type="entry name" value="DUF3545"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="60" mass="7512" checksum="2C764ADAB3F61C89" modified="2010-01-19" version="1">MDSYAFDDYMDFEPAPRRSRSKPEKRKWREIEALKDRQRLRKELQEMDLLHDYSLDDLDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z061</accession>
    <name>D0Z061_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Regulator of ribonuclease activity B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rraB</name>
        <name evidence="4" type="ORF">VDA_002924</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Interacts with the C-terminal region of Rne.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RraB family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301366.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002924"/>
    <dbReference type="EnsemblBacteria" id="EEZ41892">
        <property type="protein sequence ID" value="EEZ41892"/>
        <property type="gene ID" value="VDA_002924"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3076">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1479816at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060698">
        <property type="term" value="F:endoribonuclease inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019899">
        <property type="term" value="F:enzyme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01888">
        <property type="entry name" value="RraB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016716">
        <property type="entry name" value="RraB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036701">
        <property type="entry name" value="RraB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009671">
        <property type="entry name" value="RraB_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06877">
        <property type="entry name" value="RraB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018193">
        <property type="entry name" value="UCP018193"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89946">
        <property type="entry name" value="SSF89946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RraB" evidence="3">
        <location>
            <begin position="13"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="133" mass="15109" checksum="6C329C75A38314CF" modified="2010-01-19" version="1">MTYAELIEEQKLETREIIEALLEDGSEPDALYTIEHHFSADTFEALEAAAVEAFKLGYEVMEAEELELDPEDGGGKVVCFDAVMESALKAELIDEQAEKLIQLAEKHNIDYDGWGTYFESDEDDDEEEYDDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z077</accession>
    <name>D0Z077_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">ATP:glutamine synthetase adenylyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">ATase</fullName>
        </alternativeName>
        <domain>
            <recommendedName>
                <fullName evidence="3">Glutamine synthetase adenylyl-L-tyrosine phosphorylase</fullName>
                <ecNumber evidence="3">2.7.7.89</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="3">Adenylyl removase</fullName>
                <shortName evidence="3">AR</shortName>
                <shortName evidence="3">AT-N</shortName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="3">Glutamine synthetase adenylyl transferase</fullName>
                <ecNumber evidence="3">2.7.7.42</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="3">Adenylyl transferase</fullName>
                <shortName evidence="3">AT</shortName>
                <shortName evidence="3">AT-C</shortName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="3" type="primary">glnE</name>
        <name evidence="6" type="ORF">VDA_002940</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>[glutamine synthetase]-L-tyrosine + ATP = [glutamine synthetase]-O(4)-(5'-adenylyl)-L-tyrosine + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:18589"/>
            <dbReference type="Rhea" id="RHEA-COMP:10660"/>
            <dbReference type="Rhea" id="RHEA-COMP:10661"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:83624"/>
            <dbReference type="EC" id="2.7.7.42"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>[glutamine synthetase]-O(4)-(5'-adenylyl)-L-tyrosine + phosphate = [glutamine synthetase]-L-tyrosine + ADP</text>
            <dbReference type="Rhea" id="RHEA:43716"/>
            <dbReference type="Rhea" id="RHEA-COMP:10660"/>
            <dbReference type="Rhea" id="RHEA-COMP:10661"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:83624"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.7.89"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the GlnE family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.89" evidence="3"/>
    <dbReference type="EC" id="2.7.7.42" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002940"/>
    <dbReference type="EnsemblBacteria" id="EEZ41908">
        <property type="protein sequence ID" value="EEZ41908"/>
        <property type="gene ID" value="VDA_002940"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1391">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008882">
        <property type="term" value="F:[glutamate-ammonia-ligase] adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047388">
        <property type="term" value="F:[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000820">
        <property type="term" value="P:regulation of glutamine family amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00802">
        <property type="entry name" value="GlnE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023057">
        <property type="entry name" value="GlnE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005190">
        <property type="entry name" value="GlnE_rpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013546">
        <property type="entry name" value="PII_UdlTrfase/GS_AdlTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30621">
        <property type="entry name" value="PTHR30621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08335">
        <property type="entry name" value="GlnD_UR_UTase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03710">
        <property type="entry name" value="GlnE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 6" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GlnE" evidence="4">
        <location>
            <begin position="40"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="GlnD_UR_UTase" evidence="5">
        <location>
            <begin position="307"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="domain" description="GlnE" evidence="4">
        <location>
            <begin position="561"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="domain" description="GlnD_UR_UTase" evidence="5">
        <location>
            <begin position="836"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="region of interest" description="Adenylyl removase" evidence="3">
        <location>
            <begin position="1"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Adenylyl transferase" evidence="3">
        <location>
            <begin position="465"/>
            <end position="964"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="964" mass="110862" checksum="1B1268D19A9B4B66" modified="2010-01-19" version="1">MASVSIPSMTYLEQACDKAWQTMAQSHPKALQLWSEIEQEQLQTVVGLSDFIFQSLSRNEGLLHWVHQHKDDQSRSQEYRSQLQQQLAQAHNENNVMRILRQFRRQEMVWIAWRDFTQQTPLDECLSHLSLLAEAMIMEAYQWLYQQCCQEWGTPVNEHGEPQPMLILGMGKLGGGELNFSSDIDLIFTYPENGETQGARRSIANAQFFTRLGQRLIKALDQVTFDGFCYRVDMRLRPFGESGPLVMSYAALEDYYQEQGRDWERYAMIKARVMGKERFEQYQTLRQMLRPFVFRRYIDFSAVQSLRRMKAMIGSEVRRRGLTNNIKLGAGGIREVEFIAQSFQLIRGGREPSLRGRGLLETLAAIEELHLLDSEDSLTLKNGYVFLRRLENLLQAIDDKQTQTLPDKPLDQERLAYAMGYESWSLLQQAISEHMVRIHQIFGLLIGGEDEQETVDCASEYQELWAMVKKEDVVRTILTELEAPEVDSQTSILSSMKQELSKRTLGPRGREVLAKLMPMVLSHIVTRPDAASVLSRITKLIVRIATRTTYLELLSEHHGALEQLVRLCSASPMVAEQLAQYPILLDELLDPQHLYHPTPIDGYQDELREYLARIPEEDMEQQMEAIRQFKQTQLLRIAAADIAGALPVMKVSDHLTYLAQAIIGAVVNQAWFQMKEKYGEPTHLLEREGRGFAVVAYGKLGGIELGYGSDLDLVFLHDCPSNVYTNGKKEIDGRQFYLRLAQRIIHLFSTRTASGVLYEVDMRLRPSGASGLLVSTIDAFAQYQQQEAWTWEHQALVRARMVYGDPALQQEFTAIRQQVLAQERDKVTLRHQVVEMRLKMRAHLGHKQPGKFGLKQDIGGITDIEFLAQYLVLAYASEYKAITRWSDNVRIFDILSQCDVISYPQGQQLTQAYCEMRDAIHRLSLQEQSAYCEPTLFAEQRQWVEQAWSQWLGIEIDTDSVVFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0I8</accession>
    <name>D0Z0I8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Elongation factor P</fullName>
            <shortName evidence="8">EF-P</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">efp</name>
        <name evidence="12" type="ORF">VDA_003052</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-19 is required for alleviation.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Protein biosynthesis; polypeptide chain elongation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="8">May be beta-lysylated on the epsilon-amino group of Lys-19 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-19 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8 9">Belongs to the elongation factor P family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003052"/>
    <dbReference type="EnsemblBacteria" id="EEZ42019">
        <property type="protein sequence ID" value="EEZ42019"/>
        <property type="gene ID" value="VDA_003052"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0231">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00345"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04470">
        <property type="entry name" value="S1_EF-P_repeat_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05794">
        <property type="entry name" value="S1_EF-P_repeat_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00141">
        <property type="entry name" value="EF_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015365">
        <property type="entry name" value="Elong-fact-P_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020599">
        <property type="entry name" value="Transl_elong_fac_P/YeiP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013185">
        <property type="entry name" value="Transl_elong_KOW-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001059">
        <property type="entry name" value="Transl_elong_P/YeiP_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013852">
        <property type="entry name" value="Transl_elong_P/YeiP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011768">
        <property type="entry name" value="Transl_elongation_fac_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30053">
        <property type="entry name" value="PTHR30053"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01132">
        <property type="entry name" value="EFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08207">
        <property type="entry name" value="EFP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09285">
        <property type="entry name" value="Elong-fact-P_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005901">
        <property type="entry name" value="EF-P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01185">
        <property type="entry name" value="EFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00841">
        <property type="entry name" value="Elong-fact-P_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00038">
        <property type="entry name" value="efp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01275">
        <property type="entry name" value="EFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8 12" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="7 8" id="KW-0379">Hydroxylation</keyword>
    <keyword evidence="6 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EFP" evidence="11">
        <location>
            <begin position="54"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="Elong-fact-P_C" evidence="10">
        <location>
            <begin position="116"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(3,6-diaminohexanoyl)-5-hydroxylysine" evidence="8">
        <location>
            <position position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ42019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="173" mass="19043" checksum="470151939CA7B7C7" modified="2010-01-19" version="1">MLDNEPCVIIENEFVKPGKGQAFNRVKIRKLLSGKVLEKTFKSGESVEAADVVDVELDYLYTDGEFYHFMNNETFEQIAADVKAVGDNAKWLVENNTCTLTLWNGNPIAVTPQNFVELEVTETDPGLKGDTQGTGGKPATLSTGAVVRVPLFIQIGEVIKVDTRSAEYVSRVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0K5</accession>
    <name>D0Z0K5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Probable 3-phenylpropionic acid transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_003069</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301746.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003069"/>
    <dbReference type="EnsemblBacteria" id="EEZ42036">
        <property type="protein sequence ID" value="EEZ42036"/>
        <property type="gene ID" value="VDA_003069"/>
    </dbReference>
    <dbReference type="GeneID" id="57340459"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="791272at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026032">
        <property type="entry name" value="HcaT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024989">
        <property type="entry name" value="MFS_assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12832">
        <property type="entry name" value="MFS_1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004925">
        <property type="entry name" value="HcaT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="72"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="136"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="160"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="241"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="293"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="327"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="351"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="domain" description="MFS_1_like" evidence="6">
        <location>
            <begin position="17"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ42036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="392" mass="42929" checksum="127C6B4ADA7AE4B2" modified="2010-01-19" version="1">MFRSSPFSWTSQYLVGFFFSYGVYLPFWALWFAHIGVDAADIGVLLGLGFAVRCAANLVLTPRIHKVSHLIPALRGFSLLGLISCIVYIYCGGSLWALTLVTTFFNLAAGPVVPISDALANHYAKDGHLDYGRTRLWGSIAFIAGSTVVGLMADRYGADVIPWVAAAGLAFALLRTMHLPAIVPVDDQEQDQVRPAVLSLLKDPTVLRFLLINALIQGSHAAYYGFSSIYWKEVAGFNEATIGYLWSFSVVAEVAIFAVSKHLFSGWTITNMFRLAAVGVLIRWGVTASSTDLWVMFAVQSLHAITFATAHLAAIRYIQHAPSNQMVALQALYNAIPLGAVMAVLTTLSGWIYGIWSADVFWVMAVMALPVFFMKMEPKRHTNYAEQAKASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0L2</accession>
    <name>D0Z0L2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA-binding protein Fis</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">fis</name>
        <name evidence="4" type="ORF">VDA_003076</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the transcriptional regulatory Fis family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_002542007.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003076"/>
    <dbReference type="EnsemblBacteria" id="EEZ42043">
        <property type="protein sequence ID" value="EEZ42043"/>
        <property type="gene ID" value="VDA_003076"/>
    </dbReference>
    <dbReference type="GeneID" id="58896421"/>
    <dbReference type="GeneID" id="61875956"/>
    <dbReference type="eggNOG" id="COG2901">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1933378at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00166">
        <property type="entry name" value="DNA_binding_Fis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005412">
        <property type="entry name" value="Fis_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002197">
        <property type="entry name" value="HTH_Fis"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02954">
        <property type="entry name" value="HTH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002097">
        <property type="entry name" value="DNA-binding_Fis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01591">
        <property type="entry name" value="DNABINDNGFIS"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01590">
        <property type="entry name" value="HTHFIS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0010">Activator</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH_8" evidence="3">
        <location>
            <begin position="55"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="2">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ42043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="98" mass="11111" checksum="D578E96C33298E60" modified="2010-01-19" version="1">MFEQNLTSEALTVTTVTSQDQITQKPLRDSVKASLKNYLAQLNGQEVNDLYELVLAEVEQPLLDTIMQYTRGNQTRAATMMGINRGTLRKKLKKYGMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0N7</accession>
    <name>D0Z0N7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Bifunctional ligase/repressor BirA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Biotin operon repressor</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Biotin--[acetyl-CoA-carboxylase] ligase</fullName>
            <ecNumber evidence="3">6.3.4.15</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Biotin--protein ligase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Biotin-[acetyl-CoA carboxylase] synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">birA</name>
        <name evidence="5" type="ORF">VDA_003101</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 3">
            <text>ATP + biotin + L-lysyl-[protein] = AMP + diphosphate + H(+) + N(6)-biotinyl-L-lysyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:11756"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:10505"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57586"/>
            <dbReference type="ChEBI" id="CHEBI:83144"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.4.15"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the biotin--protein ligase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.15" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301861.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003101"/>
    <dbReference type="EnsemblBacteria" id="EEZ42068">
        <property type="protein sequence ID" value="EEZ42068"/>
        <property type="gene ID" value="VDA_003101"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0340">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1654">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1842956at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004077">
        <property type="term" value="F:biotin-[acetyl-CoA-carboxylase] ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16442">
        <property type="entry name" value="BPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00978">
        <property type="entry name" value="Bifunct_BirA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030855">
        <property type="entry name" value="Bifunct_BirA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004408">
        <property type="entry name" value="Biotin_CoA_COase_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003142">
        <property type="entry name" value="BPL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004143">
        <property type="entry name" value="BPL_LPL_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013196">
        <property type="entry name" value="HTH_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008988">
        <property type="entry name" value="Transcriptional_repressor_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02237">
        <property type="entry name" value="BPL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03099">
        <property type="entry name" value="BPL_LplA_LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08279">
        <property type="entry name" value="HTH_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50037">
        <property type="entry name" value="SSF50037"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00121">
        <property type="entry name" value="birA_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51733">
        <property type="entry name" value="BPL_LPL_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 3" id="KW-0092">Biotin</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 5" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0678">Repressor</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BPL/LPL catalytic" evidence="4">
        <location>
            <begin position="66"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="3">
        <location>
            <begin position="22"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Biotin binding" evidence="3">
        <location>
            <begin position="89"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Biotin binding" evidence="3">
        <location>
            <begin position="116"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>biotin</name>
            <dbReference type="ChEBI" id="CHEBI:57586"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>biotin</name>
            <dbReference type="ChEBI" id="CHEBI:57586"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ42068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="318" mass="34705" checksum="6328055433E04951" modified="2010-01-19" version="1">MKEHASKLKLISLLADGQFHSGEALGEALGISRAAISKQIKVLQSWGLDIYRIQGRGYCLAKSITLLDKGDILSHCICSNLDVIPVIDSTNQYLLDRVGQLPSGAVCLAEYQQAGRGRRGRQWLSPFGSNLYMSMYWRLDAGVAAAMGLSLVVGVAIAETLQSMGAERIKVKWPNDIYCDDKKVAGILVEMVGQAGDAAHLIIGMGLNISMPEQQHIDQAWTNLTDCCEQTIERNQLAARLITQLTKTLQDYEHHGLAGFVERWNKVDNFIGRPVKLLLGEQVIEGIARGINDTGALLLETEAGITPYIGGEISLRGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0S9</accession>
    <name>D0Z0S9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Der GTPase-activating protein YihI</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">yihI</name>
        <name evidence="4" type="ORF">VDA_003143</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Interacts with Der.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the YihI family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301989.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003143"/>
    <dbReference type="EnsemblBacteria" id="EEZ42110">
        <property type="protein sequence ID" value="EEZ42110"/>
        <property type="gene ID" value="VDA_003143"/>
    </dbReference>
    <dbReference type="GeneID" id="57340629"/>
    <dbReference type="eggNOG" id="COG3078">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2068666at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01058">
        <property type="entry name" value="GAP_YihI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007336">
        <property type="entry name" value="YihI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04220">
        <property type="entry name" value="YihI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="22"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ42110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="181" mass="20698" checksum="72F0EDF7C3814AE7" modified="2010-01-19" version="1">MTRKKKGRKPGSEGPAVYREKSVSQLEKEAVERKKDRKRKGLKAGSRHSSTVVTKQKSGNKPKDPRLGSKKPIPLIVEAQKPMTKKERRLSAQQELEMLENDPQLITLLDRLDAGEKLGSGLQKQVDQKLDRIEQLMKQLGLLDEPEEEMMDDELPMTRAHSDDDLLDQFEKMDFDSFGKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0T0</accession>
    <name>D0Z0T0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Methyltransferase-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_003144</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301992.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003144"/>
    <dbReference type="EnsemblBacteria" id="EEZ42111">
        <property type="protein sequence ID" value="EEZ42111"/>
        <property type="gene ID" value="VDA_003144"/>
    </dbReference>
    <dbReference type="GeneID" id="57340628"/>
    <dbReference type="eggNOG" id="COG2227">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1730305at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ42111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="213" mass="24185" checksum="669F8A1FEC832BA3" modified="2010-01-19" version="1">MPSCPLCHCASSHDFFTDKLRQYFQCNSCSLVFADPDAHLAPEDEKAVYDQHENNPQDMGYRRFLARLADPLVERIGAAPLSGLDFGSGPGPTLSVMLTELGYNMAIYDPYFAPNREALEQQYDFVTCTEAIEHFYQPAKEWGLLLSLVKPGGWLGFMTKLARDVDAFAHWHYKNDPTHVSFFSRETFSFLAERDGLEVEFVGNDVILLRKTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0V3</accession>
    <name>D0Z0V3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator AsnC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003167</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003167"/>
    <dbReference type="EnsemblBacteria" id="EEZ42134">
        <property type="protein sequence ID" value="EEZ42134"/>
        <property type="gene ID" value="VDA_003167"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1522">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019887">
        <property type="entry name" value="Tscrpt_reg_AsnC/Lrp_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01037">
        <property type="entry name" value="AsnC_trans_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AsnC_trans_reg" evidence="1">
        <location>
            <begin position="2"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="41" mass="4689" checksum="EA19CE6508C45089" modified="2010-01-19" version="1">MCRSIEELQHVLINKLQAIDEVQSTETLISLQNPISRNVKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z128</accession>
    <name>D0Z128_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">tRNA modification GTPase MnmE</fullName>
            <ecNumber evidence="6">3.6.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">mnmE</name>
        <name evidence="6" type="synonym">trmE</name>
        <name evidence="9" type="ORF">VDA_003242</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
        <text evidence="6">Binds 1 potassium ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer. Heterotetramer of two MnmE and two MnmG subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.6.-.-" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302263.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003242"/>
    <dbReference type="EnsemblBacteria" id="EEZ42209">
        <property type="protein sequence ID" value="EEZ42209"/>
        <property type="gene ID" value="VDA_003242"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0486">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="263682at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04164">
        <property type="entry name" value="trmE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00379">
        <property type="entry name" value="GTPase_MnmE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031168">
        <property type="entry name" value="G_TrmE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018948">
        <property type="entry name" value="GTP-bd_TrmE_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004520">
        <property type="entry name" value="GTPase_MnmE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027368">
        <property type="entry name" value="MnmE_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025867">
        <property type="entry name" value="MnmE_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027266">
        <property type="entry name" value="TrmE/GcvT_dom1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12631">
        <property type="entry name" value="MnmE_helical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10396">
        <property type="entry name" value="TrmE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00450">
        <property type="entry name" value="mnmE_trmE_thdF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51709">
        <property type="entry name" value="G_TRME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 6" id="KW-0630">Potassium</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TrmE-type G" evidence="8">
        <location>
            <begin position="217"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="24"/>
        </location>
        <ligand>
            <name>(6S)-5-formyl-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:57457"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>(6S)-5-formyl-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:57457"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>(6S)-5-formyl-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:57457"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="227"/>
            <end position="232"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="227"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="246"/>
            <end position="252"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="248"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="251"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="252"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="271"/>
            <end position="274"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="455"/>
        </location>
        <ligand>
            <name>(6S)-5-formyl-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:57457"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ42209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="455" mass="49850" checksum="A282F1C1E976F62F" modified="2010-01-19" version="1">MNQHTDTIVAQATPPGRGGVGIIRVSGPKAKEVALAVAGRELRPRYAEYLPFKNEDGTALDQGIALFFKGPNSFTGEDVLELQGHGGPVLMDMLIRRILTLDGIRPARPGEFSERAFMNDKLDLAQAEAIADLIDASSEEAAKSAFQSLQGAFSTRVNELVESLIYLRMYVEAAIDFPEEEIDFLSDGKVSGDLNRIIDRLEAVRKEANQGSIMREGMKVVIAGRPNAGKSSLLNALSGKDSAIVTDIAGTTRDVLREHIHIDGMPLHIIDTAGLREASDEVERIGIERAWDEILQADRVLFMVDGTTTDATDPKEIWPDFIERLPENMGLTVIRNKIELTGEQAGICHVNNPTLIRLSALTGEGVDSLRQHLKECMGFSGTTEGGFMARRRHLDALERAAEHLEIGKSQLEGYMAGEILAEELRLAQQHLSEITGEFTSDDLLGRIFTSFCIGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z185</accession>
    <name>D0Z185_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative oxidoreductase short-chain dehydrogenase/reductase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003299</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302433.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003299"/>
    <dbReference type="EnsemblBacteria" id="EEZ42266">
        <property type="protein sequence ID" value="EEZ42266"/>
        <property type="gene ID" value="VDA_003299"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4221">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1261526at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="240" mass="25958" checksum="E9500A9A2D08475C" modified="2010-01-19" version="1">MSKPLIVITGASSGIGEATARKLAGEGYPLLLLARRLDRLEALALPNTLCRQVDVTDLQALQNAIAEAEEKFGPVDCLINNAGMMLLGLADEQDPQEWKTMFDVNVMGMLNGIHLVLKGMKARKHGTVINVSSIAGRKTFPNHAAYCGTKFAVHAITENIREEVADDNVRFITIAPGAVETELLSHTTSDAIKSGYEEWKEGMGGVIAPSDIANAISYAYNQPQNLCIREIVLAATRQQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z198</accession>
    <name>D0Z198_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Probable chorismate pyruvate-lyase</fullName>
            <shortName evidence="1">CL</shortName>
            <shortName evidence="1">CPL</shortName>
            <ecNumber evidence="1">4.1.3.40</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ubiC</name>
        <name evidence="2" type="ORF">VDA_003312</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>chorismate = 4-hydroxybenzoate + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:16505"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:17879"/>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
            <dbReference type="EC" id="4.1.3.40"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the UbiC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.40" evidence="1"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302467.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003312"/>
    <dbReference type="EnsemblBacteria" id="EEZ42279">
        <property type="protein sequence ID" value="EEZ42279"/>
        <property type="gene ID" value="VDA_003312"/>
    </dbReference>
    <dbReference type="GeneID" id="57340247"/>
    <dbReference type="eggNOG" id="COG3161">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1274776at2"/>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008813">
        <property type="term" value="F:chorismate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042866">
        <property type="term" value="P:pyruvate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01632">
        <property type="entry name" value="UbiC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007440">
        <property type="entry name" value="Chorismate--pyruvate_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028978">
        <property type="entry name" value="Chorismate_lyase_/UTRA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38683">
        <property type="entry name" value="PTHR38683"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04345">
        <property type="entry name" value="Chor_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64288">
        <property type="entry name" value="SSF64288"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0456">Lyase</keyword>
    <keyword evidence="1 2" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="180" mass="20366" checksum="0C55E3E4975A3B98" modified="2010-01-19" version="1">MSDFKQLYNPLLEKAQWQVPELAQLIGSQLAPWLLETESLSQRLAQCCQHFTVTVLEQVMVEKQQLSIEEKELVGDIDCLSRKVILNGDGVPWVFARTLIPLSTLTGDEQDLAQLGEKPLGYRVFTADNARRDALVIANIRGETSPLWARRSRLWLNDKPLLVAELFLESAPIYAKDSEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1F6</accession>
    <name>D0Z1F6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA (cytidine(34)-2'-O)-methyltransferase</fullName>
            <ecNumber evidence="3">2.1.1.207</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmL</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">trmL</name>
        <name evidence="6" type="ORF">VDA_003370</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>5-carboxymethylaminomethyluridine(34) in tRNA(Leu) + S-adenosyl-L-methionine = 5-carboxymethylaminomethyl-2'-O-methyluridine(34) in tRNA(Leu) + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:43088"/>
            <dbReference type="Rhea" id="RHEA-COMP:10333"/>
            <dbReference type="Rhea" id="RHEA-COMP:10334"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74508"/>
            <dbReference type="ChEBI" id="CHEBI:74511"/>
            <dbReference type="EC" id="2.1.1.207"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>cytidine(34) in tRNA + S-adenosyl-L-methionine = 2'-O-methylcytidine(34) in tRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:43084"/>
            <dbReference type="Rhea" id="RHEA-COMP:10331"/>
            <dbReference type="Rhea" id="RHEA-COMP:10332"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74495"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.207"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.207" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302588.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003370"/>
    <dbReference type="EnsemblBacteria" id="EEZ42337">
        <property type="protein sequence ID" value="EEZ42337"/>
        <property type="gene ID" value="VDA_003370"/>
    </dbReference>
    <dbReference type="GeneID" id="57340180"/>
    <dbReference type="eggNOG" id="COG0219">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1578095at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008175">
        <property type="term" value="F:tRNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd18094">
        <property type="entry name" value="SpoU-like_TrmL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01885">
        <property type="entry name" value="tRNA_methyltr_TrmL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016914">
        <property type="entry name" value="tRNA_cyt/urid_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42971">
        <property type="entry name" value="PTHR42971"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029256">
        <property type="entry name" value="SpoU_TrmH_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00185">
        <property type="entry name" value="tRNA_yibK_trmL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 3 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 3 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="SpoU_methylase" evidence="5">
        <location>
            <begin position="3"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3 4">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 4">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 4">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR029256-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ42337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="154" mass="17438" checksum="DE2AE8FCE7116764" modified="2010-01-19" version="1">MFDIALYEPEIAPNTGNIIRLCANCGANLHLIEPLGFDLEEKKLRRAGLDYHDLAHVYRHKDFAAFKEAMGDRRLFACTTKTTNYHTNAKFEQGDVLIFGPETRGLPAEFIESLPLEQRLRIPMQPDSRSLNLSNAVAIIAFEAWRQMDFAGAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1N7</accession>
    <name>D0Z1N7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">50S ribosomal protein L5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rplE</name>
        <name evidence="10" type="ORF">VDA_003451</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the universal ribosomal protein uL5 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302809.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003451"/>
    <dbReference type="EnsemblBacteria" id="EEZ42418">
        <property type="protein sequence ID" value="EEZ42418"/>
        <property type="gene ID" value="VDA_003451"/>
    </dbReference>
    <dbReference type="GeneID" id="57340092"/>
    <dbReference type="eggNOG" id="COG0094">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1456375at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01333_B">
        <property type="entry name" value="Ribosomal_L5_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002132">
        <property type="entry name" value="Ribosomal_L5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020930">
        <property type="entry name" value="Ribosomal_L5_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031309">
        <property type="entry name" value="Ribosomal_L5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020929">
        <property type="entry name" value="Ribosomal_L5_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022803">
        <property type="entry name" value="Ribosomal_L5_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031310">
        <property type="entry name" value="Ribosomal_L5_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11994">
        <property type="entry name" value="PTHR11994"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00281">
        <property type="entry name" value="Ribosomal_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00673">
        <property type="entry name" value="Ribosomal_L5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002161">
        <property type="entry name" value="Ribosomal_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55282">
        <property type="entry name" value="SSF55282"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00358">
        <property type="entry name" value="RIBOSOMAL_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 6 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="2 6" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L5" evidence="8">
        <location>
            <begin position="25"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L5_C" evidence="9">
        <location>
            <begin position="84"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00029522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ42418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="179" mass="20356" checksum="EEC8F6EAFAB1D372" modified="2010-01-19" version="1">MAKLHDYYKETVVKELAEKFEYKSIMQVPKIEKITLNMGVGEAINDKKLLENAAADMTAIAGQKPLITVARKSVAGFKIREGYPIGCKVTLRGERMWDFFERLISIAIPRVRDFRGLNPKSFDGRGNYSMGVREQIIFPEIDFDKVDRVRGLDITITTSANSDEEARALLSAFNFPFRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1S8</accession>
    <name>D0Z1S8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MSHA biogenesis protein MshI</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003492</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303596.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003492"/>
    <dbReference type="EnsemblBacteria" id="EEZ42459">
        <property type="protein sequence ID" value="EEZ42459"/>
        <property type="gene ID" value="VDA_003492"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3166">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4972">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="650468at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007813">
        <property type="entry name" value="PilN"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05137">
        <property type="entry name" value="PilN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="330"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="483" mass="54261" checksum="67A324839C2C4CC5" modified="2010-01-19" version="1">MNFGRWFGKSTEGCSACLAIFTDEVALLYQNSEQQWCADTYILEKKEQLESALIALIEKHHLHKQNLKLALGHGLFKTLLIDKPDVPEQEWPTVLPFLVKDLLNESPMEILADAFPAATKDRLQVFVANKRQVETMVQACALKGCKVISIGVEDVLWGQFSNLEANQLIVHCRQNEGLALSAFKQQVLCFQRQLRGFSTPIVASNNEQIDNLTLELQRSLDFLSTQFRGSTISKIMVACDGDDNSVLAQQLKANFNLLVEPIVDPDPIIKTNSLRLAWAMLTQHLPVSIELYRDEFRPKKEWLTLTNVVLGWTISAVLLAAIWGWSAWSNKLAQEQLALQQEKLDAEQAKIEAIKAELALKIPSPAKVTFESELEQKIAKTQATLKAIANHDDSLKVGYSSMLQQLADAANGNIQLLNIHVEGKNLNLSGIARQPSSVPQWLKEFGQYSSLNQRQFESMKLGRNEQKQVTFSLTAKREEKVNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1Y2</accession>
    <name>D0Z1Y2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001972</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CvfB family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40940">
        <property type="protein sequence ID" value="EEZ40940"/>
        <property type="gene ID" value="VDA_001972"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2996">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014464">
        <property type="entry name" value="CvfB_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039566">
        <property type="entry name" value="CvfB_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040764">
        <property type="entry name" value="CvfB_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37296">
        <property type="entry name" value="PTHR37296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17783">
        <property type="entry name" value="CvfB_WH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13509">
        <property type="entry name" value="S1_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF012524">
        <property type="entry name" value="YitL_S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S1" evidence="2">
        <location>
            <begin position="38"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="S1" evidence="2">
        <location>
            <begin position="113"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR012524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="248" mass="27739" checksum="222BB5C843B70876" modified="2010-01-19" version="1">MPSQSVPAGTNVGDKIKVFLYNDSHDEVVATTDEPIAQVGEFAKMRVEGITTVGAFLDWGLRKNLLLPYSEQRRKLQEGEEILVRVYTDRATGRIVASTKFNRFLDKTPATYKVGDEVPVLIAEITDLGYKAIINNQHWGLLFKTECFGKLFIGKTLKAYVKEIREDGKINLSLQKMGKARMDDLSDKILTSLEKKGGFIPLSDKSTPEEIFNVFRTSKGTFKKTIGGLYKQGLIVIGKDGIRLNDND</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z212</accession>
    <name>D0Z212_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Lipoprotein releasing system transmembrane protein LolC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">VDA_001859</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298830.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001859"/>
    <dbReference type="EnsemblBacteria" id="EEZ40827">
        <property type="protein sequence ID" value="EEZ40827"/>
        <property type="gene ID" value="VDA_001859"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4591">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="768211at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042953">
        <property type="term" value="P:lipoprotein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011925">
        <property type="entry name" value="LolCE_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02212">
        <property type="entry name" value="lolCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="25"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="270"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="311"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="344"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="368"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="10">
        <location>
            <begin position="29"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="9">
        <location>
            <begin position="296"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ40827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="402" mass="43787" checksum="C3EBCEA1C4C531CF" modified="2010-01-19" version="1">MFHPVSFFIGLRYLRGRSGDRFSRFVSYMSTAGITIGVMALVTVLSVMNGFEDQLKSRILGVLPQAVITDASGRMLESDSAPAVLTQMDHVTKVVPITRGEVVIQSAQSISAGTMLGIDPNKYEVIADHMVLGALDKLTPNSFNVVIGQALAVQLGVRVGDQIRLMVTSVSQYTPLGRIPSQRKFTVVGIYDTGSNVDEELVYTNIQDAGRLLHFKSDQMSGWRLYLDDPFVVTELEQQPLPNHWQWTDWRAQRGELFQAVKMEKNMMGLMLGLIIGVAAFNIISALIMVVMEKQSEVAILKTQGMTNHQILAIFMVQGSSSGVIGAVFGGILGTLFSVNLNTVMSIIGVRLSAIGGSLPVVIEPVQIIIVIIGAILLSLLATVFPSYRAASVRPAEALRYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z214</accession>
    <name>D0Z214_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Lipoprotein releasing system transmembrane protein LolE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">VDA_001861</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298832.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001861"/>
    <dbReference type="EnsemblBacteria" id="EEZ40829">
        <property type="protein sequence ID" value="EEZ40829"/>
        <property type="gene ID" value="VDA_001861"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4591">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="768211at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044874">
        <property type="term" value="P:lipoprotein localization to outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042953">
        <property type="term" value="P:lipoprotein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011925">
        <property type="entry name" value="LolCE_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011926">
        <property type="entry name" value="LolE_gammaproteobact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02212">
        <property type="entry name" value="lolCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02213">
        <property type="entry name" value="lolE_release"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="21"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="271"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="314"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="380"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="10">
        <location>
            <begin position="30"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="9">
        <location>
            <begin position="301"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ40829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="414" mass="45351" checksum="670BADD7BE0D5372" modified="2010-01-19" version="1">MFRPLSLYIGSRFSRAKKRNRMVSFISMSSTIGIAVGVAVIILGLSAMNGFERELQNRVLAVIPHGELEAVKPPLQDWQPIIKRVEQSPLVTGAAPYVQFTALLEKGAKLKAVGIRGVDPKDETKVSALPKFVLDNAWSNFKAGHKEIIIGQGIANKLKVKRGDWLTAMIPSADPDAKLKAPHRIRLQVAGILALGGQIDHTLAIVPLQDAQQYLDMGDGVSGISLNVTDVLNAQHIVKEVGYTLPVYVYLKSWTQKFGYLYRDIQMVRTIMYLVMVLVIGVACFNIVSTLMMAVKDRSADIAILRTMGAQDRLIKSIFVWHGLMSGVVGSLIGAVVGSLLAINLTAIVKVIEKLVGHRFLSGDIYFVDFLPTQLSIHDVILVSITAILLSLVATWYPARRASRLHPAQVLSAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z277</accession>
    <name>D0Z277_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Hypothetical ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001922</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298946.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001922"/>
    <dbReference type="EnsemblBacteria" id="EEZ40890">
        <property type="protein sequence ID" value="EEZ40890"/>
        <property type="gene ID" value="VDA_001922"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1131">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1179151at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="8"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="40"/>
            <end position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="286" mass="32010" checksum="695367734E14DE00" modified="2010-01-19" version="1">MDLSHPFIEINQLNKTYGSQCALSNVSLTLSPGRVLGLLGHNGAGKSTLIECILGLRASHEAIKVFGLDPVRDHIGVMSNLSYLSDSNSLPMWMTVKQLIKYVSGMNSHFDKVQAMQYLKDTDIELKAKIGRLSKGMKLQLHLALVMAIDAKVLILDEPTLGLDLIYRERFYTDVLDWYKKGNRSLIIASHEIDEIEHLLTDIVILKQGKVVLSESREDLELRFNALSTGEETKDKALMLNPIYSKKVLGQWSFLFKDRDIAELSSLGHVAKPSLSEIFLAIQQGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2B4</accession>
    <name>D0Z2B4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATP/GTP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000565</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304729.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000565"/>
    <dbReference type="EnsemblBacteria" id="EEZ39545">
        <property type="protein sequence ID" value="EEZ39545"/>
        <property type="gene ID" value="VDA_000565"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0488">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="318943at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13304">
        <property type="entry name" value="AAA_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase_AAA_core" evidence="1">
        <location>
            <begin position="234"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="460" mass="53387" checksum="08B4FA3EF57B9A66" modified="2010-01-19" version="1">MKRSKIEYVRIEKLYGHKSFDVKFDDNQLIIVGENGLGKSTIINILFYTLTSQWQKLLKYQFKSIEVGVDGKDYKFTFEEIESIYDDASDTPILQLLMKLKSMGLTATQAYNNFTPKLFGQLRNENFSSPSKVRKVLGDLSLSNYSLNDIPQSLVALESALNFHVLYLPTYRRIERDLKQIFPSLEDDLKKYNRYHSSFIRNREHIELVEFGMQDVQSMISSKMNELENEFRSSLETLTSGYLRVILRKEYMQEESLPTYKFNDSELDAIFEKIERDGSFFSSDDLINLRRTAHALNEGSLSSDIDMLSAHLIKQLLNLHKNQLNKEDKVRTFAKLTNSYLKGKKFEFDNKEFRLPLVPDFENSEFILCESPNEIDLGLLSSGEKQIVSLFAHMYLSDFDDYLVIIDEPELSLSVPWQKRLLEDIALTSNCSGLIAVTHSPFIYNNTLKNKAKSLMEFYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2C5</accession>
    <name>D0Z2C5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative multidrug efflux membrane fusion protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000576</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304749.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000576"/>
    <dbReference type="EnsemblBacteria" id="EEZ39556">
        <property type="protein sequence ID" value="EEZ39556"/>
        <property type="gene ID" value="VDA_000576"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0845">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1532186at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019339" evidence="2">
        <location>
            <begin position="20"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="3">
        <location>
            <begin position="60"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="377" mass="40593" checksum="8668DA228DE85BD2" modified="2010-01-19" version="1">MKKPLLLATLIGSALLVGCGETASGQKPAMAPLAQAQSVQLIQYQQGKSYVGRTEAVEDVAISAQVSGYLKERLFEEGQMVKKGQPLFRIESAAYEAQVKSAAAAISQAKAQVQRSNMDFARAQDLLPKGNISKSEYDRLLAEKLNAQAQLESAQAMYSAAKVDLSHTTITAPFSGRVSDSKVSIGDLISPSSGVLTTLVSLDPMHAAFTISERERLNMGLDKLDGSGNGNNKGLVEVVLTLNNGQQYSEIGSLDFVGNRIDLNTGTLAMRAQFANSNQQLLPGQHVQIFLREKTPQQVMVIPRSAVQSDLEGDFVMVLKDGKVAERRNVTMGSQTDQGVIISQGLKADEEVITIGLQRIRNGMTVRLQNEDSAPKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2G1</accession>
    <name>D0Z2G1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">5'-nucleotidase</fullName>
            <ecNumber evidence="5">3.1.3.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_000612</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the 5'-nucleotidase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.5" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304870.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000612"/>
    <dbReference type="EnsemblBacteria" id="EEZ39592">
        <property type="protein sequence ID" value="EEZ39592"/>
        <property type="gene ID" value="VDA_000612"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0737">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1884225at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106411">
        <property type="term" value="F:XMP 5'-nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009166">
        <property type="term" value="P:nucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008334">
        <property type="entry name" value="5'-Nucleotdase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036907">
        <property type="entry name" value="5'-Nucleotdase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006179">
        <property type="entry name" value="5_nucleotidase/apyrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575">
        <property type="entry name" value="PTHR11575"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02872">
        <property type="entry name" value="5_nucleotid_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01607">
        <property type="entry name" value="APYRASEFAMLY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55816">
        <property type="entry name" value="SSF55816"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="3">
        <location>
            <begin position="10"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="5_nucleotid_C" evidence="4">
        <location>
            <begin position="373"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="586" mass="64211" checksum="6C8A8B2F658708DB" modified="2010-01-19" version="1">MINNRSAKITFAHINDTHSNFEPSSISLTLPADVFSSETSVYASCGGFSRVSSAVKEIKTQAYLNQREFMFLHAGDCFQGTLYFSLYKGSANAVLLNAIGIEAMALGNHELDMGNAPLADFLDQVQFPLLAGNWDLSQEDQSKPNPIRDKENVYAYDVQTQTAKYIVKDVLGEPVAIFGLALENMVGIANPDPDTHFLNVSQICRDTVSHLNQQGINKIIVLSHLGYDRDLELAEEVVGLGAIIGGHSHTMQGDFTNIGFGKTDTYARMVNGTCVVQAGCNALALGQLDIDFAADGTVERVSGVNQLLLGRQFTVDATRTEHLDQDSHDAVRHYLTEQANVRFCVKDPVIENILNEHYRPAVRNLQVEQVALVTEPLRHTRIPDQKGPSQIAPWVVQSFVWKGRQLGYDIDFGIHNAGGVRASLNPGPITPADVAGKLLPFAIGLMVYQVKGKRIRQALEGAIDNAIDNGVEGTGTGSFPYVADLRYTYRCCSTKGTRIEQLQHLSDGQWIDVDDEKVYTSVSSGYTATGKEGYAPLLDYVSEPKAMNVTMADAFEDFARMKGEFSAPEENYTVYIPCECNATDVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2H3</accession>
    <name>D0Z2H3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CMD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000624</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304901.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39604">
        <property type="protein sequence ID" value="EEZ39604"/>
        <property type="gene ID" value="VDA_000624"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2128">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1893149at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051920">
        <property type="term" value="F:peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004675">
        <property type="entry name" value="AhpD_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003779">
        <property type="entry name" value="CMD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02627">
        <property type="entry name" value="CMD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="SSF69118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00778">
        <property type="entry name" value="ahpD_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CMD" evidence="1">
        <location>
            <begin position="14"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="147" mass="16686" checksum="61F41FA73DB268D9" modified="2010-01-19" version="1">MQHRFDLSALEPKAYKPMLGLEGYLDQTDLEPKLKELIKIRSSIINGCVFCIQMHTDKAKSLGETDHRLFAVAAWKESPLFTDEERSVLALTDEVTEIAKGGVSEEVYQACIKLMGEHKTAQCLMQIVTINAWNRIALTTRMYHEAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2H7</accession>
    <name>D0Z2H7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Hypothetical chromate resistance protein-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_000628</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000628"/>
    <dbReference type="EnsemblBacteria" id="EEZ39608">
        <property type="protein sequence ID" value="EEZ39608"/>
        <property type="gene ID" value="VDA_000628"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2059">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015109">
        <property type="term" value="F:chromate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003370">
        <property type="entry name" value="Chromate_transpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02417">
        <property type="entry name" value="Chromate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="48"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="79"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="113"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ39608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="177" mass="18843" checksum="E369E40E5AD83B0E" modified="2010-01-19" version="1">MPFIANILPIANIFNIFYQAGSFVFGGGHVVLPLLQPMMDGLVEPDKFLTAYASAQLVPGPMFTMASYLGAAAYTTSPILGSLVATIAVFLPGALLLFAFLPAWEALFSHPRLQIAISLVNASVVGLLASAFISPVFTSSIHSIFDLIVVITGGILLKRYNLPIWGLASLLALYTLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2M2</accession>
    <name>D0Z2M2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF2326 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000673</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305022.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39653">
        <property type="protein sequence ID" value="EEZ39653"/>
        <property type="gene ID" value="VDA_000673"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5293">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1105801at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018760">
        <property type="entry name" value="DUF2326"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10088">
        <property type="entry name" value="DUF2326"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2326" evidence="1">
        <location>
            <begin position="423"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="534" mass="61707" checksum="CB43D70960EEBACD" modified="2010-01-19" version="1">MLKSISCEKLIDITLTFQHGLNSVVGADDAHNSIGKSSILMLIDFAFGGDDFTTKCDDVIKNVEDFDLAVTFEFDKTYSFVRNTGSSDSVYHVEEQELLTIEEYRNFLKNSYGIDKFELSFRECVSAFYRVYQRDNYNDKRPLDNFPKETWASIRKRILKLFNEYHAISKLEQDKKTETENKNNIKGTFNTGVISKINKTTFKNNEAKLHEINEQITSIKSALEANVTDIKSIINSKNAELKRNKDTLVDLKFKLDTSLSRIEDNLSKTKLKNSRSFNELVDFFPEIDKERLSQVDAFHCGISKIMREQLNEEKLALIQNINELDIEIGKIDSELLKIVNSKEGSIYLLEKLIELDRLEKQLSQQNDFWLKEDQATHKIKSIKTEIKETLVQSIDNIQTEINKGLTEYIRKIYLGNPISPELRILDNDYVFYRGDDRGTGKGFANMISLDLTILEKTCLPAIIHDSLLFKNMDVTSIENLIATYASFNKQIFISIDEVSKYKDETRDLIEKSKFIKLDKDRVAFGQKWKTETIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2X5</accession>
    <name>D0Z2X5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Maltoporin</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Maltose-inducible porin</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">lamB</name>
        <name evidence="10" type="ORF">VDA_000776</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in the transport of maltose and maltodextrins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homotrimer formed of three 18-stranded antiparallel beta-barrels, containing three independent channels.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Cell outer membrane</location>
            <topology evidence="2 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="induction">
        <text evidence="9">By maltose.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the porin LamB (TC 1.B.3) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000776"/>
    <dbReference type="EnsemblBacteria" id="EEZ39756">
        <property type="protein sequence ID" value="EEZ39756"/>
        <property type="gene ID" value="VDA_000776"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4580">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046930">
        <property type="term" value="C:pore complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042958">
        <property type="term" value="F:maltodextrin transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015481">
        <property type="term" value="F:maltose transporting porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01346">
        <property type="entry name" value="Maltoporin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01301">
        <property type="entry name" value="LamB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023738">
        <property type="entry name" value="Maltoporin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003192">
        <property type="entry name" value="Porin_LamB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036998">
        <property type="entry name" value="Porin_LamB_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02264">
        <property type="entry name" value="LamB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword evidence="9" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0626">Porin</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0732">Signal</keyword>
    <keyword evidence="5 9" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="9" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5009009111" description="Maltoporin" evidence="9">
        <location>
            <begin position="25"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="site" description="Greasy slide, important in sugar transport" evidence="9">
        <location>
            <position position="32"/>
        </location>
    </feature>
    <feature type="site" description="Greasy slide, important in sugar transport" evidence="9">
        <location>
            <position position="64"/>
        </location>
    </feature>
    <feature type="site" description="Greasy slide, important in sugar transport" evidence="9">
        <location>
            <position position="97"/>
        </location>
    </feature>
    <feature type="site" description="Important in sugar transport" evidence="9">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <feature type="site" description="Greasy slide, important in sugar transport" evidence="9">
        <location>
            <position position="251"/>
        </location>
    </feature>
    <feature type="site" description="Greasy slide, important in sugar transport" evidence="9">
        <location>
            <position position="379"/>
        </location>
    </feature>
    <feature type="site" description="Greasy slide, important in sugar transport" evidence="9">
        <location>
            <position position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ39756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="416" mass="45473" checksum="366AE8C754729E2C" modified="2010-01-19" version="1" precursor="true">MKLNKVCLTAAAVSAALMSTASMAADVDFFGYMRAGVGISGDHGQQFEFEKNNLGRLGNEGDAYGEIGLGSNIYQQDDMTFRVNTMLAATSNGSNDWEGTEKDDAKIALRQLNVEAKGVLGFAPEATLWAGKRYYQRHDIHITDRYYWDISGAGAGIENIAMGPGKLSLAWVRSDREAEDFNPIPDEIQPLNMNILDARYAGLNLWDGASLELGIDYAIANPDHDANQAAKDAKDGVMLTAELTQSVLGGFNKTVVQFGNEGYGAPMVYGGAGNWYAAEAKHGGSAYRLINHGVISLGEHWDLSHQLVWASTIDDIQDGQKQDITNFSAVVRPVYKWDDHHKTIFEAGYFANDGATDANNSGGQKYTLAQAWTAGSSFWARPEIRLYASYLKNDDGKFAGNKDNEYNIGVQAEAWW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2Z1</accession>
    <name>D0Z2Z1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">MotA/TolQ/ExbB proton channel family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">VDA_000792</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the exbB/tolQ family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305364.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000792"/>
    <dbReference type="EnsemblBacteria" id="EEZ39772">
        <property type="protein sequence ID" value="EEZ39772"/>
        <property type="gene ID" value="VDA_000792"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0811">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1796180at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017270">
        <property type="entry name" value="MotA/TolQ/ExbB-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002898">
        <property type="entry name" value="MotA_ExbB_proton_chnl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01618">
        <property type="entry name" value="MotA_ExbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037714">
        <property type="entry name" value="TolR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018801" evidence="9">
        <location>
            <begin position="24"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="262"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="352"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="390"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="domain" description="MotA_ExbB" evidence="10">
        <location>
            <begin position="310"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="59"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ39772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="454" mass="48933" checksum="7167FE3E90051709" modified="2010-01-19" version="1">MKVKTLAFALSVVMPLWTGHVYADSLVSKAQQEQAVQTAHNAAREQGFHHTETGIKAQRDALLAKRKQLQNQTDKLSKSFSQNEEQLAELEEKLRLETGSLGELFGVVRQAAKDLNHELDNSVTSLGANHDDNVVADIVAAKSLPSMAQLTGLWRTMIGQIQASDEVAKVEIPYVNGAGELNQVSGFRLGSFGLITDEGYVNWNSGRGNAEAFPIQPENGPTSASFEHLNQTGIMDIVIDPSRGEMLAQLANEPTLMDRLKAGGVVGQIILVLLAIGGGIALFRGANLIKIRQQINRQLKNPEQPGNNPLGRILSVYNKEQNRSVEALELRLMETIIDEQQGLEKGLSMLKLLAALAPMLGLLGTVTGMIETFQVITQFGNGDPKVMAGGISMALVTTVLGLIAAMPLLLAHNVLGTQAENIRNILEKQGISLVAEQAEKACFKPNTQSKVAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z337</accession>
    <name>D0Z337_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative periplasmic iron siderophore binding protein of ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000838</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305491.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="SMR" id="D0Z337"/>
    <dbReference type="STRING" id="675817.VDA_000838"/>
    <dbReference type="EnsemblBacteria" id="EEZ39818">
        <property type="protein sequence ID" value="EEZ39818"/>
        <property type="gene ID" value="VDA_000838"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0614">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1473468at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002491">
        <property type="entry name" value="ABC_transptr_periplasmic_BD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01497">
        <property type="entry name" value="Peripla_BP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50983">
        <property type="entry name" value="FE_B12_PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018810" evidence="1">
        <location>
            <begin position="24"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="domain" description="Fe/B12 periplasmic-binding" evidence="2">
        <location>
            <begin position="42"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="355" mass="40383" checksum="727E97A5458E4AD0" modified="2010-01-19" version="1">MNKKIIGFCFAFILGLNPVNALAITVTDMMQNQVSIDSPPKRAAIATVPIASLLISLTDQPEHLVGVHPFVKETLLDGTLGQHYPQLHTLKTDVIARNFTPNIEALLALHVDLVVQWGHLNPKLYKRLQAAQIPTITLLYGTEHYSQQWITIMGEISGQSDKASHLLTQRKAWIEKLQQQQQRYQTKPKVLYLSSCKGSRCFSMSGNSNVQFDIELAGGINLTQDIHTQQNTSINMEQIIEWDPDIILLGNFDKNFMRQDIEKNALLSYTTAAKKHQIYKIPQAGFIWDVPSHENPAYWLWLSAIFHPSAPIKLTTIDLKQMIKQWYGIELTPQDIKAILKTDINRYDAILQFDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z345</accession>
    <name>D0Z345_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000846</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305514.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000846"/>
    <dbReference type="EnsemblBacteria" id="EEZ39826">
        <property type="protein sequence ID" value="EEZ39826"/>
        <property type="gene ID" value="VDA_000846"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1196">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="31450at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="399"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="568"/>
            <end position="602"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="979" mass="112331" checksum="199CF4B9114DECD6" modified="2010-01-19" version="1">MLKNAIDNLLISISRLIAIDSAGVAIAEIDLREGGILIGGGNIGKTSILNAIRLFLLPEENFKDSKNKFGFSDKEGNFYSNDECFEHYFPSSTSFLILECDNYLGGPIPHCQILYRGSSEKLDYRRLFTSLRYEQIRHLFWDDNAGDDGIGGRINDLSLSKVQAYLKSHDKHFKPLVRSSAIRDIIYANQLLDIDAMRFCLFPLNSTKDADVDAFRALVRLLFDMKTGSDTVRLAVANIIESRKKERKDELNFDIDAFINHNEKLSRSELTLKKIESLRPVYEKLVLSHQQLVSNKHAEDALMQYAMMLDSRITHEKQILEQEEKRLTLQKGKVSSAKKACDGTLDKQKTLQGEINALSRRQKKLDDTVQKTSLIVNQYDESETIESIVSGHRGHLADKEQALALKQDAQKRQTELEDLKQEVGKLEEMEALYLTSINAQEYKLFNQLPESVWMKLAAVNLEIAESNPTRPLTLSEQQAIKSFTDLLEEQEQHYTLWGLELEPIQVDNRESDQIRLSKVQETLERKRKRMLDLSAMDSQSRFERVKDISVLETEIKRTRNEISLLLAYTNDSHQLTEINKELAEAEQARDSLGKQFNTQNEQLVQEKLLVEAQTGKLTEKKEQLEELNGYQVRAKAELQAHHLPVSDFSVLPDQTVDLSEETLHKRIESLYRKRQAKTDVTERLQDFVREQVLENDDKLMLSHLDDELLEHAFHQLQTRYQGLDEEFDILRKHFIEHKHSVHAIINELKNNREMVRQFEQSINRAFQGVVINDLSQVEAKIKVEARFDDLVNEIEFFDTHSDQKASEQFIDRLKAFSKKFFPEGKAALLTMEQIVSGISYRVKKQGQEGWETKSQSTSTIMLINIKLVEILLGRLRNSACSTQFPLVIDEGASVDSSQFDWLLPNMKQAGFRVLSASTNSASSEIIFKFGQHFRLDAMRTATPYSKARTIAFTGMPEGFVTKGSQLDREQLDMFGEADE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-12-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z381</accession>
    <name>D0Z381_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Outer membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000882</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000882"/>
    <dbReference type="EnsemblBacteria" id="EEZ39862">
        <property type="protein sequence ID" value="EEZ39862"/>
        <property type="gene ID" value="VDA_000882"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2885">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07185">
        <property type="entry name" value="OmpA_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006664">
        <property type="entry name" value="OMP_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006665">
        <property type="entry name" value="OmpA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036737">
        <property type="entry name" value="OmpA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00691">
        <property type="entry name" value="OmpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01021">
        <property type="entry name" value="OMPADOMAIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103088">
        <property type="entry name" value="SSF103088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51123">
        <property type="entry name" value="OMPA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OmpA-like" evidence="3">
        <location>
            <begin position="56"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="188" mass="20407" checksum="14778A4602448F23" modified="2010-01-19" version="1">MALSLFGCSISAQQPPVATQTKDLRDFDSDGVINARDKCADTPLGAVVDNDGCPTYVKTDEKNSVHVLFANDSTVIPETYMAQLKKTAQFLETFPETHIELKGYASPVGNSAHNQYLSDTRAANVRQQLIDFGVAADRIKTVGFGDADPIQAETSEASNTLSRRVVAQVVGSKGHVVDQWTIFTVREN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3E0</accession>
    <name>D0Z3E0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Capsular polysaccharide synthesis enzyme CpsA sugar transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_000941</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial sugar transferase family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305786.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000941"/>
    <dbReference type="EnsemblBacteria" id="EEZ39921">
        <property type="protein sequence ID" value="EEZ39921"/>
        <property type="gene ID" value="VDA_000941"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2148">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1759731at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003362">
        <property type="entry name" value="Bact_transf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017475">
        <property type="entry name" value="EPS_sugar_tfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017473">
        <property type="entry name" value="Undecaprenyl-P_gluc_Ptfrase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02397">
        <property type="entry name" value="Bac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03025">
        <property type="entry name" value="EPS_sugtrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03023">
        <property type="entry name" value="WcaJ_sugtrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="76"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="114"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="284"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="Bac_transf" evidence="8">
        <location>
            <begin position="279"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ39921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="469" mass="53190" checksum="6CC1539582BA0CF3" modified="2010-01-19" version="1">MKRQSLMIVDDGYNILLKACDFIIINLVLSLLIQGQVKNETVVDFAAGFLFSVIFILIGEYCSLYKKNVRLNISKSLIKCTLTFVLTTVAWLILRNQLMSLEGMEYSNLRQLMVHGWFALSLTFLLLFRTTVIFVIQSCWKKMAVKKIAIIGLTSGGIAVEAALRKELKGQNFTIEYYDDRDESRFGYMTKASFKGKVDTLLQKAKQGDIDEVYVALPMVARDRIQYFLRLLSDTTVETYIVPDLYTYNNAINQIREIDGVQTLSVFASPLDGLGDVIKRIEDIIIGGLITLMISPVLIAVAIGVKLSSPGPILFKQDRYGLGGKCIKVWKFRSMKVMENDAVVTQATKNDPRVTKFGAFIRRTSLDELPQFFNVLQGSMSIVGPRPHAVAHNEEYRVLVDNYMIRHKVKPGITGLAQVNGYRGETDTLDKMEMRVHYDIRYIQSWSLFLDLKIIFMTVFKGFVGETAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3G1</accession>
    <name>D0Z3G1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">High-affinity choline uptake protein BetT</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_000962</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305843.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000962"/>
    <dbReference type="EnsemblBacteria" id="EEZ39942">
        <property type="protein sequence ID" value="EEZ39942"/>
        <property type="gene ID" value="VDA_000962"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1292">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1217683at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071705">
        <property type="term" value="P:nitrogen compound transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000060">
        <property type="entry name" value="BCCT_transptr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30047">
        <property type="entry name" value="PTHR30047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02028">
        <property type="entry name" value="BCCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00842">
        <property type="entry name" value="bcct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="84"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="119"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="193"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="231"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="277"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="310"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="364"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="394"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="437"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="490"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="520"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="554" mass="59567" checksum="876BBE8A9C87EB92" modified="2010-01-19" version="1">MSNDNNGGIQRPDGKVKAIDTDYQIGQDNIALKVGPFGLDIHNRVFAISGMFIILFVVFTLLFREQVEPFFSGLRNWLTSNMDWFFLSAGNIFVLVCLGLIVTPLGRVRIGGTEATPDYSYAGWLAMLFAAGMGIGLVFFGVSEPMSHFSSALGGVTVENGVRTDWAPLMGAEGNTEAAAALGMAATIYHWALHPWSVYALLALGLAIFSFNKGLPLTMRSIFYPLFGERVWGWVGHIIDILAVVATVFGLATSLGYGASQAATGLNFLFGVPMTDTTQIVLIVIITALALISVVAGLDSGVKRLSEINMGLAALLLLFVIVVGPTLAIFTGFFDNIVSYLKNLPALSVPFAREDVNYSQGWTAFYWAWWISWSPFVGMFIARVSRGRSVREFIVCVILIPSTVCVLWMTAFGGTAISQYVTTGYQAVFDADLPLKLFAMLDIMPFATITSIIGIVLVVVFFITSADSGSLVIDTIAAGGKVDAPVPQRVFWCTFEGLVAIALLLGGGLAAAQAMAVTTGLPFTFVLLVATVSLIKGLMSEPRPARKSRKTATQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3L1</accession>
    <name>D0Z3L1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001012</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305984.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001012"/>
    <dbReference type="EnsemblBacteria" id="EEZ39992">
        <property type="protein sequence ID" value="EEZ39992"/>
        <property type="gene ID" value="VDA_001012"/>
    </dbReference>
    <dbReference type="GeneID" id="57342509"/>
    <dbReference type="eggNOG" id="ENOG5032T0Z">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1566441at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021501">
        <property type="entry name" value="DUF3157"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11355">
        <property type="entry name" value="DUF3157"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019377" evidence="1">
        <location>
            <begin position="23"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="196" mass="21524" checksum="869C0A612EA0FF89" modified="2010-01-19" version="1">MHLKYRLISAAVLGLLSASVSAQQVVELKDGRLIQLNDDFTWQYVQKQQATTAKPEVEVLEASAQLAPVTAVPFTNTVVGTQFKLNSSKPILQLSQSGIDAILQPAYYQGNELVIPVGLTNQGTDSVVLVKMNITLADANGKSLASESVKVWSAIKRMPETYLRAKTQKQGLPIKLKVPSFSNYQIKAEITEVEHW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3N7</accession>
    <name>D0Z3N7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DNA photolyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001038</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001038"/>
    <dbReference type="EnsemblBacteria" id="EEZ40018">
        <property type="protein sequence ID" value="EEZ40018"/>
        <property type="gene ID" value="VDA_001038"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3046">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036134">
        <property type="entry name" value="Crypto/Photolyase_FAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007357">
        <property type="entry name" value="PhrB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04244">
        <property type="entry name" value="DPRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48173">
        <property type="entry name" value="SSF48173"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="516" mass="61078" checksum="C938AFC4EAFA8DB4" modified="2010-01-19" version="1">MMEYKTIRLILGDQLNIHHSWFRNIDHSTLYLLIEIKQETDYVVHHIQKVCAFFAAMKAFAQELTQQGHHVLYLTLDETEQYENLGQLIEVYIKETKAEKFEYQEPDEYRLDNQIKAYSFPCSIACVDNEHFLLSRQEINEQFTADKHTVMEHFYRRMRKRFNILMEVDKPIGMKWNFDKNNREKLKSIDIKNLPQPLCFNNDVSEIVQRLNRHRIKTIGDEQSVLLWPINRQQALTLLNHFCHVCLPFFGQFQDAMTHTSPSTKWSLYHSRLSFCLNCKLLSPLEVMNIAISHFEQKNNNIDIAQIEGFIRQILGWREYIRAIYWVNMPKYKDKNALNSSRPLPQFFWNGDTKMLCQREAIQQSLSFAYAHHIQRLMVTGNFCLLAEIDPSEVDNWYLGIYIDAIEWVELPNTRGMALFADGGIVGTKPYCASGSYINKMSDYCKHCKYDIKLRHGENSCPLNSLYWHFMNKHDLLLAKNPRTRMILRTWDNMDDKQKQAILDTAQYYLANLEHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3T2</accession>
    <name>D0Z3T2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional repressor of aga operon</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001083</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306179.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001083"/>
    <dbReference type="EnsemblBacteria" id="EEZ40063">
        <property type="protein sequence ID" value="EEZ40063"/>
        <property type="gene ID" value="VDA_001083"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1349">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1629121at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014036">
        <property type="entry name" value="DeoR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001034">
        <property type="entry name" value="DeoR_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00455">
        <property type="entry name" value="DeoRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08220">
        <property type="entry name" value="HTH_DeoR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00420">
        <property type="entry name" value="HTH_DEOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51000">
        <property type="entry name" value="HTH_DEOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH deoR-type" evidence="3">
        <location>
            <begin position="4"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="258" mass="28149" checksum="8CA0C72953CC93B0" modified="2010-01-19" version="1">MKSAVERRMEIVNVVNRDGKARVEDLASQFNVSSVTIRSDLSFLEKNGYVVRSHGAAIPNSGVIAELTVHEKRRQNAGIKTAIGQAAAKLIHNGDTVILDSGTTTREIASNLKTVEDVVVMTNGLDVAMELASAPGVEVLMSGGVLRKNALSFSGSQAETGLKNYRFDKVFLGVDGFDLRAGITTHNEQEASLNRLMCEISERVIAVVDSTKFGKRSCHMIREFGHIDTVVTDSDIPEDYLQGLRDMKVDVIIVEKEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z408</accession>
    <name>D0Z408_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted nucleoside-diphosphate-sugar epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001161</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306378.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001161"/>
    <dbReference type="EnsemblBacteria" id="EEZ40139">
        <property type="protein sequence ID" value="EEZ40139"/>
        <property type="gene ID" value="VDA_001161"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0702">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1616572at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="1">
        <location>
            <begin position="6"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="283" mass="31581" checksum="E284ABFBEEB52D71" modified="2010-01-19" version="1">MILVTGASGHIGQGVVKELLNNNVEFVAGVRNPETYHGIECALRAFDYDDTSMMQEAFRGVDTVIFISGNAETERRIEQHRQIIDAAKQENIQHIVYLSFITVTDPNSVFPFTRQHIDTENYLNHSGIKHTVIRSSWYMENLEFAVKEALDTDIFIDGSQRGALSFISRQDVAKGLAMLAIKPELQGEIYTFTGSKAYAMRDVAELMNCHCGKGIEFKSISIADYQQSLIDDGLPEFLAESIALNSDDIDNGDYAIVSQDAKLVNQQQPIALVDYLTSICAFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4K0</accession>
    <name>D0Z4K0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_000458</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304420.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39438">
        <property type="protein sequence ID" value="EEZ39438"/>
        <property type="gene ID" value="VDA_000458"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1757088at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020449">
        <property type="entry name" value="Tscrpt_reg_HTH_AraC-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00032">
        <property type="entry name" value="HTHARAC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="4">
        <location>
            <begin position="156"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="255" mass="29232" checksum="E647848F85859F17" modified="2010-01-19" version="1">MALIDHQTTFDLNLIDNQIVGIAAQVGRHDSGLHKHNKDQLLYAPFGCMNITLDSQKLLLPPTRAAWIPANTIHCAKMTNVVEYRSIYFDTALTQDLKLSLKTVEVNPLLQALIERMAFWSWEKPFVEMTNTYRLFLDELVEAKEQTLALPLPQDRRLQLWLEKLNQHDQPIDNLAQLSLKIGASSKTISRIFSNETGMSFQEWRQQWRLIQAIEKLTAGYQVNDVAYQLGFSSDSAFIAFFKQQTGTTPLKYLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4K4</accession>
    <name>D0Z4K4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000462</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304430.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39442">
        <property type="protein sequence ID" value="EEZ39442"/>
        <property type="gene ID" value="VDA_000462"/>
    </dbReference>
    <dbReference type="GeneID" id="57342631"/>
    <dbReference type="eggNOG" id="ENOG502Z91E">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="937464at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="192"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="339" mass="37472" checksum="C80AAC7BB4E52629" modified="2010-01-19" version="1">MWTVYSFTGASILASIVFSLLLFLSIDNDPLMKVLFGGLAVIFELGKFFAWYEVGERRARKNYGGALSALLFYAVLAAISIGGSIGGINSATNQAQSHVNVQKSKINAYNMQIAAIEKQIELNNQAAEKYIQMERIASGVSRIQRANEKLREDQQKLAIERDSLPVVSQGSVLGLIDSLANSLNISPQKAQLGLVVFLSVLLDFFAAFFVGLIGEENRFRQQYRQLNALSLAGINGQVKEIKLLEHFNPSEVGTSEISDEEIEVTIVPEPEPEEPKTPYEQTIDALSTNKVNCTKRAVSNFLKLPTDEVDAIFKQLLEEGIVTKKPNNHYQWIGVKDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4M9</accession>
    <name>D0Z4M9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome c oxidase subunit CcoO</fullName>
            <ecNumber evidence="7">1.9.3.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_000487</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.9.3.1" evidence="7"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304501.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000487"/>
    <dbReference type="EnsemblBacteria" id="EEZ39467">
        <property type="protein sequence ID" value="EEZ39467"/>
        <property type="gene ID" value="VDA_000487"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2993">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1469969at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003468">
        <property type="entry name" value="Cyt_c_oxidase_monohaem-su/FixO"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02433">
        <property type="entry name" value="FixO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00781">
        <property type="entry name" value="ccoO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="6">
        <location>
            <begin position="52"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="199" mass="22334" checksum="54B0668699F3A713" modified="2010-01-19" version="1">MAKLNADFTQSVIILILSTVLVASFSLLVWVVPFFFNTEQLKAESTAKPLTVLQVAGRDIYISEGCHTCHTMMVRPLPAEVMRYGKYSKESDDIYEHPNLWGSKRTGPDLTNLGRKYSDQWHAIHLENPRHVVPSSIMPAYPWLFHKTLSGDDIEAKLHALQTLGVPYSENEISQARLAIKGKTHAEALIAYLQSLGVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4N3</accession>
    <name>D0Z4N3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">6-phospho-beta-glucosidase</fullName>
            <ecNumber evidence="6">3.2.1.86</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_000491</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 1 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.86" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304511.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000491"/>
    <dbReference type="EnsemblBacteria" id="EEZ39471">
        <property type="protein sequence ID" value="EEZ39471"/>
        <property type="gene ID" value="VDA_000491"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2723">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="654705at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008706">
        <property type="term" value="F:6-phospho-beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103047">
        <property type="term" value="F:methyl beta-D-glucoside 6-phosphate glucohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001360">
        <property type="entry name" value="Glyco_hydro_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018120">
        <property type="entry name" value="Glyco_hydro_1_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033132">
        <property type="entry name" value="Glyco_hydro_1_N_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10353">
        <property type="entry name" value="PTHR10353"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00232">
        <property type="entry name" value="Glyco_hydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00131">
        <property type="entry name" value="GLHYDRLASE1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00572">
        <property type="entry name" value="GLYCOSYL_HYDROL_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00653">
        <property type="entry name" value="GLYCOSYL_HYDROL_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5 6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ39471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="467" mass="53425" checksum="745980DF14DA6690" modified="2010-01-19" version="1">MTTQTLGFPPHFLWGGAIAANQVEGAYNQDGKGLSTSDMLPKGILSPHQPRSERTSGIKDIAIDFYHRYPEDISLFKEMGFTTLRLSIAWTRIFPNGDELEPNELGLAYYDRIFDELAKHDIQPFVTLSHYEMPMYLTEQYGGWADRRLIDFFERYARTVFERYKNKVKLWLTFNEINMSLHAPFTGVGLAEDSTEQQIYQAIHHQLLANAKAVNLCHQIIPNAKIGNMLLGAMNYPLTCTPDDVIAAMHENNKWLFFGDVQVRGRYPGYMLRYFRENDIQLEIEEGDLELLANASVDFVSFSYYASGCASADPKQKETGNIVASVPNPYLEKSEWGWLIDPKGLRYLLNFLWDRYQKPLFIVENGLGAHDQMTSDGEILDDYRIQYLNDHLVQAREAVADGVDLMGFTCWGPIDLVANSTAEMSKRYGFIYVDRHNDGSGSLTRTRKKSFYWYQQVIATHGQSLTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4Q4</accession>
    <name>D0Z4Q4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Ribose ABC transport system permease protein RbsC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_000512</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304582.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000512"/>
    <dbReference type="EnsemblBacteria" id="EEZ39492">
        <property type="protein sequence ID" value="EEZ39492"/>
        <property type="gene ID" value="VDA_000512"/>
    </dbReference>
    <dbReference type="GeneID" id="57342795"/>
    <dbReference type="eggNOG" id="COG1172">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1254678at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="56"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="172"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="228"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="282"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ39492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="328" mass="34502" checksum="7896EA93E33F516F" modified="2010-01-19" version="1">MSTKTMKADNAQSNSNKLFTKEWLIEQKSLIALIFLIVVVSFLNPNFFTVDNILNILRQTSVNAIIAVGMTLVILTAGIDLSVGSVLALCGAFAATLIAMEVPVLIAVPTALLAGAILGAISGVIIAKGKVQAFIATLVTMTLLRGVTMVYTDGRPISTGFTDVADSFAWFGTGYAMGIPVPIWLMVIVFAAAWYLLNHTRFGRYVYALGGNESATRLSGINVDRVKIGVYAICGFLSALAGIIITSRLSSAQPTAGMGYELDAIAAVVLGGTSLAGGKGRIMGTLIGALIIGFLNNALNLLDVSSYYQMIAKAVVILLAVLVDNKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4R2</accession>
    <name>D0Z4R2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000520</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304603.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000520"/>
    <dbReference type="EnsemblBacteria" id="EEZ39500">
        <property type="protein sequence ID" value="EEZ39500"/>
        <property type="gene ID" value="VDA_000520"/>
    </dbReference>
    <dbReference type="GeneID" id="57342803"/>
    <dbReference type="eggNOG" id="ENOG502ZANK">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1979400at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016870">
        <property type="entry name" value="UCP028137"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028137">
        <property type="entry name" value="UCP028137"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="149"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="189"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="228" mass="25473" checksum="AF903ABE01F2F06D" modified="2010-01-19" version="1">MTEKKNSPLSEIIFNVIVPSVILMKFSGEQDLGAVGALLVALAFPIAFGGYELIRYKKYNFISLLGIVSVLMTGGIGLLELDNKWLAIKEAFIPGVIGLVVLGSSFTRYPIVKKMILNDTVLNLETIKTRLSEVNKEAEFDRCLTVSNYLFASTFVFSSVMNYVLAKMIVTSPTGTEAFNEELGRLTLLSYPMIAIPSMLMMFGIFYFVWRQIRSMTQLETSQIFNAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4T3</accession>
    <name>D0Z4T3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">TraB pilus assembly</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000166</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000166"/>
    <dbReference type="EnsemblBacteria" id="EEZ39150">
        <property type="protein sequence ID" value="EEZ39150"/>
        <property type="gene ID" value="VDA_000166"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3170">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="34"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="156"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="85"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="162"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="404" mass="45028" checksum="9B04B4FA4F142D70" modified="2010-01-19" version="1">MDIKALFSRKESDSLDEQPTALEGDNTSNYKKNLVVAATVSAMFAICYLAFKLITAPPQVEIEPEPDYEPVITSDFTQKDSLSALQAQQQTIEKMQTTINGLVRQRDSLSEQIKSGMEQLDTRFTKAFEEAQRNWLNDMDALQERMNNQPPPIVPDMNEFPSGHSDNPNGRVNPDPFGTLSDQEPYYPKPYPREYDKPDLKDIPVSKRQGIQTFSYSWPRAGSQTVYRRSSENYVPTGSFVTAVLIGAADANAGVNAQGDTAPILFRAIHNGILPNGKRSHLKGCFFTASVYGEISSNRGIARLQNMSCIFEKQKGKEEIIDIPVQGTAFNFGRNGMRGTPVMRNGKIMQMAGQLMSNYINPMGTMPLPISAPKPQVNNPLMQQLPADLQQKAVDYNQIQQSPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z507</accession>
    <name>D0Z507_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000240</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306705.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000240"/>
    <dbReference type="EnsemblBacteria" id="EEZ39224">
        <property type="protein sequence ID" value="EEZ39224"/>
        <property type="gene ID" value="VDA_000240"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="64" mass="7313" checksum="DCE7795DEEF36487" modified="2010-01-19" version="1">MDNVIQLLNAQYDIYPSKDHVEEIALIYQYLIDKFGDTSTTAFKLHEVLISLAHIAERDGATPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z562</accession>
    <name>D0Z562_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000112</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306883.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000112"/>
    <dbReference type="EnsemblBacteria" id="EEZ39096">
        <property type="protein sequence ID" value="EEZ39096"/>
        <property type="gene ID" value="VDA_000112"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3209">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1521871at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018947" evidence="1">
        <location>
            <begin position="20"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="325" mass="37165" checksum="4E3FA385A59985D4" modified="2010-01-19" version="1">MKKFLSVAILLALSSAANATQKSVFPDAVDPALTACTDLRLDKLVRKGASQSSDLTVGNYKYNTDGKIIQRAYLDSTFDYEYNIDGTLKKASALRAMNREGIIIEHTKENFISDYTYENGKVTREVRQVFSSSASDLNGAPEVTYQINYFYDANDKLTRREQINQANNSKILYTYTFNDQDRLSKINEERKTGNQITDRDVLLLTYNDDGEIIKAVHKKPLMGNTTDEPPIIKTVDISYYASNDDVYPFYYVDPIKEWKVDRDFFGLSFHRIQKIVTTDPTKTISISYVYQDDNEDFLPDSFTATMAITFGDKQQTVVQQYSLEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z585</accession>
    <name>D0Z585_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">IncF plasmid conjugative transfer pilus assembly protein TraH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000016</name>
        <name evidence="3" type="ORF">VDA_000045</name>
        <name evidence="4" type="ORF">VDA_000135</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000008">
        <property type="protein sequence ID" value="EEZ38990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="ADBS01000005">
        <property type="protein sequence ID" value="EEZ39060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306945.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000008.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000016"/>
    <dbReference type="EnsemblBacteria" id="EEZ38990">
        <property type="protein sequence ID" value="EEZ38990"/>
        <property type="gene ID" value="VDA_000016"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39060">
        <property type="protein sequence ID" value="EEZ39060"/>
        <property type="gene ID" value="VDA_000045"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39119">
        <property type="protein sequence ID" value="EEZ39119"/>
        <property type="gene ID" value="VDA_000135"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502ZB1J">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1819710at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010927">
        <property type="entry name" value="T4SS_TraH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06122">
        <property type="entry name" value="TraH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5007650157" evidence="1">
        <location>
            <begin position="19"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ38990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="457" mass="49246" checksum="E280A1A2AAEC2A7B" modified="2010-01-19" version="1">MKKLAILIPLMLSNPTVAGVDSDLGSFFDGLTFEGNATLPQSYQGQAANYYTGGSAYIRTPVKQMQLATITVPEINAGCGGIDLFAGGFSFINSDQLVSMGKAIVSNAVPFAVDLALQTWAPQLKNVKDRLEAIAREINALSVNSCEAAQAGISALAGFAGVGEKNYICATMGTQNNSFADWAAAKNGCNNEASANQQVKNATNDPKLKDFVAANRNIIWYSLHKNGFLSGDRQLAEFFMSLSGTIVYDDKMSATRYPSLLTSSNNLIEVMTQGGEASYYRCDTSGQNGCLKPTQATLTINQDKALKHRVAVLLRSIITKYRSDQGLSNNETQFLDSVSLPVLKMMTVSLESGYSLESSINAYAQVISTDLVTAYLQDALKVIQGALDSKGSNPEDVAALYIVIGQASEQMRLSRIQALQTLEAEQSIIRATMELEQRVEGSFSGQARQNLLFGQDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5A1</accession>
    <name>D0Z5A1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fido domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_000151</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306991.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000151"/>
    <dbReference type="EnsemblBacteria" id="EEZ39135">
        <property type="protein sequence ID" value="EEZ39135"/>
        <property type="gene ID" value="VDA_000151"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3177">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1232677at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025230">
        <property type="entry name" value="DUF4172"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003812">
        <property type="entry name" value="Fido"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036597">
        <property type="entry name" value="Fido-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040198">
        <property type="entry name" value="Fido_containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13504">
        <property type="entry name" value="PTHR13504"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13776">
        <property type="entry name" value="DUF4172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02661">
        <property type="entry name" value="Fic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140931">
        <property type="entry name" value="SSF140931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51459">
        <property type="entry name" value="FIDO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fido" evidence="4">
        <location>
            <begin position="112"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="205"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="209"/>
            <end position="216"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="247"/>
            <end position="248"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for autoinhibition of adenylyltransferase activity" evidence="3">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR640198-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR640198-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR640198-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="367" mass="42076" checksum="13C3204181A53917" modified="2010-01-19" version="1">MWIWQQQDWPMFTWDNSVIEPRLREVRFKQGILLGKMTSQSQDTAKTKLDTLLANIIHSSAIEGEKLNAFSVRSSLANKLGISEERPFPTTEQTEGLAEIMVDAVENLEEPLTLERILHWHDRLFPAGYTLFNPVIGGQLRGDVPMQVVSGRIDRPVVHFEAPQRAILDDELAQFIEWFNTSKLDASFDPLLRAAITHLWFVTLHPLDDGNGRITRLLTDLALAQAEQQSVRFYAMSVGILANRKSYYEILEQTQKGGMDITPWLEWFFNTLEETFAEALKEIDQTVYKTNFWRHVDQTKLSAEQVKVLNRMLDGDFEDGINTDRYHKVAKVSKPTATRHLAALVEFKCLVKSDSGGRSTRYHLPKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5A2</accession>
    <name>D0Z5A2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Chromosome segregation ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000152</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306993.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000004.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39136">
        <property type="protein sequence ID" value="EEZ39136"/>
        <property type="gene ID" value="VDA_000152"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5033CKJ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1546191at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="199" mass="22560" checksum="28EE4FF4FD5430BD" modified="2010-01-19" version="1">MKLLPLLLMVLLSGCNQSNEKEKEKPIPSPLPQVTEIIKTPELVEELKAQPTIDDQFSMLYDKFDHILDRSESLTGPDENNDGIRDDIGAFIDALEVTEPVRNALKQNARYTQENLYHDWSEKTEANIVKAMRMGDKYNKVIACKKFVGIDVDDRINTSNTITALTYNTKARTMAYLKYNHLQDGSVSTLLPAEAKHCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5C3</accession>
    <name>D0Z5C3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000005">
        <property type="protein sequence ID" value="EEZ39045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005307058.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000005.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39045">
        <property type="protein sequence ID" value="EEZ39045"/>
        <property type="gene ID" value="VDA_000030"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031PT5">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="270" mass="31462" checksum="29FD0CD8FB6FE3EB" modified="2010-01-19" version="1">MSRAEQSQTQKAIAQRINELGSNKNEWRKAQFPYCTRRTLLAFAKFIDNPHAYENQLHDLLHCQTRVGGLQKRQRMNCVKVITVLMSKMDVENYQIGFAKSAEMETITHAWFMARYEQFWGETISLKRYYHTIHLLKMADYLVVDAVFVYDEEVPPALDDNGPIKEEDAPRIYSKAAYKTITAKFMGIFGLENDEGVVKSKLQAVKNRLAKGLSNIWWVYAPYSYSYTWTKRQLARVTKRDRVTGKERDRYPQGKVIEPDILGGNYLTEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5G4</accession>
    <name>D0Z5G4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha-helical coiled coil protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000071</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000006">
        <property type="protein sequence ID" value="EEZ39016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005307150.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000006.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000071"/>
    <dbReference type="EnsemblBacteria" id="EEZ39016">
        <property type="protein sequence ID" value="EEZ39016"/>
        <property type="gene ID" value="VDA_000071"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1196">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1405526at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021104">
        <property type="entry name" value="KfrA_DNA-bd_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11740">
        <property type="entry name" value="KfrA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="KfrA_N" evidence="2">
        <location>
            <begin position="8"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="113"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="325" mass="36669" checksum="2E76A8E90E0E1E1E" modified="2010-01-19" version="1">MARERSFTDQQIINAVSQLIIDGKNINGTSLRNQIGVGRPTALMSAYEELKEKGLIETPQLTVVESTEIKHQVLPPEIADQASIMLADIERMIHSINDHAHFTVEQRLNSAINEANVRASEAAKREADSLEQQNKAFEQLEDALDDIDELTEKMGLIQQELNQLKTKYELSENNRQNAEQANTELKHQLNANEKQLSELQSKNQELEQKNTQLNTQLISAQKEIDSLNANAISSAQTVQNLEKLNAKLEGQLQLTTSSLDQAKQELTNSSQTILSLEKLKTEHTTLINSMQNAVKEKNKELEGQRVRIDRLIEENTNLIKNTPMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5I4</accession>
    <name>D0Z5I4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">RepA protein putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000002</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000007">
        <property type="protein sequence ID" value="EEZ38995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000002"/>
    <dbReference type="EnsemblBacteria" id="EEZ38995">
        <property type="protein sequence ID" value="EEZ38995"/>
        <property type="gene ID" value="VDA_000002"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004322">
        <property type="entry name" value="Plasmid_replicase_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03090">
        <property type="entry name" value="Replicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ38995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="354" mass="40635" checksum="DC323ED5A32C0038" modified="2010-01-19" version="1">MTRVSFTSSKTTQISCYCSPIQLIIMNLLTKRVEKHLAKKPYCSNDKTASLIRNAATALLYPTIQLNPPHLCAWLIFDIDQVFKGFISDYQFSGTYVWEDSDLPLPNYVAINSSNGHYHLAYAISAVFTTENARVHPLEYLAAIERTYTRLLNADANYVGLMTHNPLHDKWQTIVFHHHEYSLAELQNGMKLDPKKKKAVNLGGYSRHIDLFDTLRFAAYERVVDSNVDYDTLYSELLELADKTNREHFSEPLSSLRAVTKSVAKYCIRNRATIYIGNKPKERKLQLDESQPLATRQAIGAIYTNEKRSNDVLEKMRYAYNHLINKDIKATQKAVQERSGVGIATVKRYWKEIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVP1</accession>
    <name>D0YVP1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ferric iron ABC transporter iron-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001206</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297636.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001206"/>
    <dbReference type="EnsemblBacteria" id="EEZ40184">
        <property type="protein sequence ID" value="EEZ40184"/>
        <property type="gene ID" value="VDA_001206"/>
    </dbReference>
    <dbReference type="GeneID" id="57339938"/>
    <dbReference type="eggNOG" id="COG1840">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1567509at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026045">
        <property type="entry name" value="Ferric-bd"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002825">
        <property type="entry name" value="CfbpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019152" evidence="3">
        <location>
            <begin position="22"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR002825-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="337" mass="37681" checksum="EC670CBADB07E512" modified="2010-01-19" version="1">MKKLLASAILAGLAVPQMATAAEEVNVYSYRQPFLVEPMFKEFTKETGIKVNVKFAKEGLAEKLQQEGEYSPADVVLTTDISRLVELSDKKLVQAVDNKVIEANVPAQYRDSEDEWFALTLRARNVYSSKDRVGQLPESFDYLDLAKPEWKGKICTRSGKHPYNVSLVSSMIAHYGEAETKQWLEGVKANLARKPQGNDRAQVKAVKEGLCDLAIGNSYYLGKMINDPEQKAWAEAVYIDFPGQKANGTHVNVSGMAMAKYAPNKANATKLMEFLTGDKAQQMYAEVNYEYPVKNGVKRSELVESWGEFTADTLPLEKVAEYHNSAIKLLDETKFDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVP7</accession>
    <name>D0YVP7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Hypothetical ABC transporter ATP-binding protein yadG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001212</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297648.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001212"/>
    <dbReference type="EnsemblBacteria" id="EEZ40190">
        <property type="protein sequence ID" value="EEZ40190"/>
        <property type="gene ID" value="VDA_001212"/>
    </dbReference>
    <dbReference type="GeneID" id="57339932"/>
    <dbReference type="eggNOG" id="COG1131">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1926714at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="4"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="37"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="307" mass="34369" checksum="86D64A8623225CD5" modified="2010-01-19" version="1">MNALEIKNLNKIYKGGVNALKNMSLEVKKGDFFALLGPNGAGKSTTIGIISSLVNKTSGSVSIFGFDLDKQKVEAKNQLGLVPQEFNFNPFETVEQIVMNQAGYYGVERSVAKERAKKYLSQLDLWGKRGERARNLSGGMKRRLMIARALMHEPKLLILDEPTAGVDIELRRSMWTFLRSINEQGVTIILTTHYLEEAEMLCRNIGIINHGELIENTTMKSLLSKLEAETFILDLSAPIETVALEQVVWRLLDSTTLEIEINKGESLNHVFAQLSEQGINVQSMRNKANRLEELFVTLVAQAKEDKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVP8</accession>
    <name>D0YVP8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transport permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_001213</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell inner membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the ABC-2 integral membrane protein family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297650.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001213"/>
    <dbReference type="EnsemblBacteria" id="EEZ40191">
        <property type="protein sequence ID" value="EEZ40191"/>
        <property type="gene ID" value="VDA_001213"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1891092at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC_2_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006648">
        <property type="entry name" value="DrrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00164">
        <property type="entry name" value="ABC2TRNSPORT"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="100"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="136"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="170"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="224"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="ABC2_membrane" evidence="8">
        <location>
            <begin position="9"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ40191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="256" mass="28103" checksum="696153D917A6BDED" modified="2010-01-19" version="1">MRHQYWIAFKSLITKEVHRFTRIWVQTLVPPAITMTLYFIIFGNLIGSRIGEMHGFSYMAYIVPGLIMMSVITNSYSNVASSFFSSKFQRNIEELLVAPVPNYIIIAGYVGGGVLRGLGVGFIVSMVSLFFVKLSIAHIGVVIATVVLTSIVFSLGGLINAVFARTFDDISIIPTFVLTPLTYLGGVFYSIDLLPEFWQGVSKLNPIVYMVNAFRYGFLGVSDVGIGTSFAVLVVLVAALYAVAYHLISKGIGLRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVT8</accession>
    <name>D0YVT8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ATP-dependent RNA helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_002019</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the DEAD box helicase family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002019"/>
    <dbReference type="EnsemblBacteria" id="EEZ40987">
        <property type="protein sequence ID" value="EEZ40987"/>
        <property type="gene ID" value="VDA_002019"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0513">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4 8" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="6">
        <location>
            <begin position="6"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="7">
        <location>
            <begin position="221"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="366"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="381"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ40987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="402" mass="44966" checksum="7ED5B122CBA76C97" modified="2010-01-19" version="1">MQEQAIPLALTGVDVMAGAQTGTGKTAAFALPMLHRLMSYPAASELHADEAEQTEQRKQPALIRGLVLTPTRELAQQVYDNVMTYCKHTDLKVVVAYGGTSMNVQVKALQQGADIVIATPGRLIDHMHVGTLSLKYLECFVLDEADRMLDMGFIIDIKRIMKRMAAERQTLFFSATFSKQVKKLAFDIMTEPKMVEVTPANTAAETVQQMVYPVDKHRKRELLSYLIGSRNWQQVLVFTKTKQGSDELVKELGLDGIKAASINGDKSQGARQRALDDFKSGKVRALVATDVAARGIDIEQLEYVVNFDMPFKPEDYVHRIGRTGRAGSAGHAITLMSLDEEWILKGIEELLDTRLPQQWLEGFEPDPLATVETTMPKRSAEKRRAKAKAKIHQNRGKNNRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVU3</accession>
    <name>D0YVU3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">1,4-dihydroxy-2-naphthoyl-CoA synthase</fullName>
            <shortName evidence="3">DHNA-CoA synthase</shortName>
            <ecNumber evidence="3">4.1.3.36</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">menB</name>
        <name evidence="4" type="ORF">VDA_002024</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 3">
            <text>2-succinylbenzoyl-CoA + H(+) = 1,4-dihydroxy-2-naphthoyl-CoA + H2O</text>
            <dbReference type="Rhea" id="RHEA:26562"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57364"/>
            <dbReference type="ChEBI" id="CHEBI:58897"/>
            <dbReference type="EC" id="4.1.3.36"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Quinol/quinone metabolism; 1,4-dihydroxy-2-naphthoate biosynthesis; 1,4-dihydroxy-2-naphthoate from chorismate: step 6/7.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Quinol/quinone metabolism; menaquinone biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.36" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299205.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002024"/>
    <dbReference type="EnsemblBacteria" id="EEZ40992">
        <property type="protein sequence ID" value="EEZ40992"/>
        <property type="gene ID" value="VDA_002024"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0447">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1275789at2"/>
    <dbReference type="UniPathway" id="UPA00079"/>
    <dbReference type="UniPathway" id="UPA01057">
        <property type="reaction ID" value="UER00167"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008935">
        <property type="term" value="F:1,4-dihydroxy-2-naphthoyl-CoA synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009234">
        <property type="term" value="P:menaquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01934">
        <property type="entry name" value="MenB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010198">
        <property type="entry name" value="DHNA-CoA_synthase_MenB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43113">
        <property type="entry name" value="PTHR43113"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01929">
        <property type="entry name" value="menB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 3" id="KW-0474">Menaquinone biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="88"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="141"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="271"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between two neighboring subunits</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="286"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between two neighboring subunits</note>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalysis" evidence="3">
        <location>
            <position position="100"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalysis" evidence="3">
        <location>
            <position position="169"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalysis" evidence="3">
        <location>
            <position position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="298" mass="33539" checksum="D8CFC20A0DC46E8F" modified="2010-01-19" version="1">MTDKTIFNPELWDEVAGFDFEDITYHRAKDQGTVRIAINRPDCLNAFRPKTVDELFTALDHARQWSDVGCVLLTGNGPSHKGQWSFSSGGDQRIRGKDGYKYEGEEAGTADVARMGRLHILEVQRMIRFMPKVVIAVVPGWAVGGGHSLHVVCDLTLASKEHAVFKQTDPDVASFDSGYGSAYLAKMIGQKRAREIFFCGFNYSAQEAYEMGMVNKVVPHYELDEEALRWAKEINSKSPTAMRMLKYGFNLPDDGLVGQQLFAGEATRLAYGTDEAQEGRDAFLEKRDQDFSKFPWHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW24</accession>
    <name>D0YW24_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative type I restriction-modification system subunit S</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001287</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-I restriction system S methylase family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297792.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001287"/>
    <dbReference type="EnsemblBacteria" id="EEZ40262">
        <property type="protein sequence ID" value="EEZ40262"/>
        <property type="gene ID" value="VDA_001287"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0732">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="827072at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.220.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000055">
        <property type="entry name" value="Restrct_endonuc_typeI_TRD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044946">
        <property type="entry name" value="Restrct_endonuc_typeI_TRD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01420">
        <property type="entry name" value="Methylase_S"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0680">Restriction system</keyword>
    <feature type="domain" description="Methylase_S" evidence="4">
        <location>
            <begin position="38"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="Methylase_S" evidence="4">
        <location>
            <begin position="231"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="421" mass="46702" checksum="60421AEE81BA54E8" modified="2010-01-19" version="1">MKFKSYSFKELLSNIVDNRGKTCPVGDAGLPLIATNCIKEHSLYPVYEKVRYVSDETYTNWFRGHPQPGDMIFVCKGSPGRVNWVPDPVNFCIAQDMVAIRADTTKVYPKYLFALLRSQASQQKILNMHVGSLIPHFKKGDFGNLYFELPEDLEYQKKVGDAYFDFCLKIESNNQLNQTLEQMAQAIFKSWFVDFDPVKAKMNGEQPVGMDADTALLFPEKLVESELGLIPEGWEVGSLSSIVDVIMGQSPKGTTYNDQGEGTPLVNGPVEFGVYHPVAQKWTTAPTKLSKNKDLIVCVRGSTTGRYVVSDGEYCLGRGVCSIRSDDSPAFANYLFKSHLNNLLNLTTGSTFPSWSGPTLKNFKVVVPPQSIIGKFETIVGNLCSMMAQNTGENESLSLLRDTLLPKLLSGEIDLAPQGNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW66</accession>
    <name>D0YW66_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Zn-ribbon-containing, possibly nucleic-acid-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001351</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297902.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001351"/>
    <dbReference type="EnsemblBacteria" id="EEZ40326">
        <property type="protein sequence ID" value="EEZ40326"/>
        <property type="gene ID" value="VDA_001351"/>
    </dbReference>
    <dbReference type="GeneID" id="57339745"/>
    <dbReference type="eggNOG" id="COG5595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1598701at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016908">
        <property type="entry name" value="UCP029037"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10071">
        <property type="entry name" value="DUF2310"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029037">
        <property type="entry name" value="UCP029037_Zn_ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="257" mass="29138" checksum="3FFD37911BF7C31A" modified="2010-01-19" version="1">MYVVELSFECFTDTTISAVDGAINGLMDAFRYNGQVIGREFPAIIDDAIFRVRAVCPEKESLHPQFHSPQVSARLDKLAAAGLLTPKIKILGRDLNSEAVAEDFQPSWQVLYTTYVHTCSPLRCGETLMPIPLYRLGKTLEGDHKTAVKWQTEWQACDEIQMAGSSQVEQAVVHEIRDIDSDLFQRGMMLRSQIETLSEVPTYYYQYQVGGESLEQERLRLCPSCGGQWFVGEAIHGIFHFKCDQCRIVSNISWEFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW93</accession>
    <name>D0YW93_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Probable peptidoglycan glycosyltransferase FtsW</fullName>
            <shortName evidence="10">PGT</shortName>
            <ecNumber evidence="10">2.4.1.129</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Cell division protein FtsW</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Cell wall polymerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Peptidoglycan polymerase</fullName>
            <shortName evidence="10">PG polymerase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ftsW</name>
        <name evidence="12" type="ORF">VDA_001175</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Peptidoglycan polymerase that is essential for cell division.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>[GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-di-trans,octa-cis-undecaprenyl diphosphate + beta-D-GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate = [GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-di-trans-octa-cis-undecaprenyl diphosphate + di-trans,octa-cis-undecaprenyl diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23708"/>
            <dbReference type="Rhea" id="RHEA-COMP:9602"/>
            <dbReference type="Rhea" id="RHEA-COMP:9603"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58405"/>
            <dbReference type="ChEBI" id="CHEBI:60033"/>
            <dbReference type="ChEBI" id="CHEBI:78435"/>
            <dbReference type="EC" id="2.4.1.129"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="10">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell inner membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <text evidence="10">Localizes to the division septum.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the SEDS family. FtsW subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.129" evidence="10"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297574.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001175"/>
    <dbReference type="EnsemblBacteria" id="EEZ40153">
        <property type="protein sequence ID" value="EEZ40153"/>
        <property type="gene ID" value="VDA_001175"/>
    </dbReference>
    <dbReference type="GeneID" id="57339970"/>
    <dbReference type="eggNOG" id="COG0772">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1133883at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008955">
        <property type="term" value="F:peptidoglycan glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043093">
        <property type="term" value="P:FtsZ-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00913">
        <property type="entry name" value="PGT_FtsW_proteobact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018365">
        <property type="entry name" value="Cell_cycle_FtsW-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013437">
        <property type="entry name" value="FtsW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001182">
        <property type="entry name" value="FtsW/RodA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30474">
        <property type="entry name" value="PTHR30474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01098">
        <property type="entry name" value="FTSW_RODA_SPOVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02614">
        <property type="entry name" value="ftsW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00428">
        <property type="entry name" value="FTSW_RODA_SPOVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="10 12" id="KW-0132">Cell division</keyword>
    <keyword evidence="10" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="2 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 10" id="KW-0133">Cell shape</keyword>
    <keyword evidence="9 10" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3 10" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 10" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="119"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="156"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="179"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="203"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="288"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="321"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="357"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="387"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="416"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ40153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="434" mass="47913" checksum="3199EEACE62CEB5B" modified="2010-01-19" version="1">MLNMIRNGISSVGDWFVKPAKPCLYDRQLVWIAIALMITGLVMVTSASVPVATRLTGMPFYFAFRHAFFLACSLAIASVVMQIPIERWHKYSIPMLLTSIFLLIVVLAIGRSVNGAARWIPLGIFNLQPAEVAKLSLFMFVSGYLVRQNKQVRETFLGFLKPLLVLGILGFLLLQQPDLGSFVVMFVGTVGMLFIAGAKLWQFLVMIASALVGIGLLIAFEPYRMRRVTSFLDPWQDPFGSGYQLTQSLMAFGRGEWWGQGLGNSIQKLEYLPEAHTDFVFAVLAEELGLAGVIVVLLLLFALVAKALIIGRKCLKSGQLFGGYLAFGFAFWFAFQTLVNVGAAAGMVPTKGLTLPLISYGGSSLFIMAAAVAILIRIDHEQRLAERLSPEDTEEDDQVISEDNPQIADNNLVLVDESETKSEDQQLKKNDEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWC3</accession>
    <name>D0YWC3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative transmembrane ABC transporter protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_001386</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297977.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001386"/>
    <dbReference type="EnsemblBacteria" id="EEZ40361">
        <property type="protein sequence ID" value="EEZ40361"/>
        <property type="gene ID" value="VDA_001386"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4174">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1479518at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="9"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="117"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="152"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="203"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="262"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="307"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="113"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="343" mass="38254" checksum="90AE5832FFDC9BFC" modified="2010-01-19" version="1">MLHYFIRRLFLVIPTFLGITLLIFAITRLVPGGPVERMLASMHSQMDGGVSLSQSGESSALSQDQLAELNAFYGLDQPVTTAYINWLTKLVTLDLGESTRYYEPVTEMIAERLPVSLFYGAMTFVISYLISIPLGYYKALKHGSWFDSSSSILIFLGFALPGYVVGVLLITWFSYHLEWFPMGGFVSDDFDEHLSLWAQIKDLMWHAVLPLICYLIGDFATLTMTMKNNLMENLSADYLRTAMAKGLPFRTAVRKHALRNSLIPIASHFGNSLLFFMSGSFLIEVIFNIDGIGLLGYESVMERDYPVVMGIVAINAAMLLVGNILSDMCVAMVDPRVRFGAPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWV9</accession>
    <name>D0YWV9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Erythronate-4-phosphate dehydrogenase</fullName>
            <ecNumber evidence="5">1.1.1.290</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">pdxB</name>
        <name evidence="10" type="ORF">VDA_001532</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>4-phospho-D-erythronate + NAD(+) = (R)-3-hydroxy-2-oxo-4-phosphooxybutanoate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:18829"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58538"/>
            <dbReference type="ChEBI" id="CHEBI:58766"/>
            <dbReference type="EC" id="1.1.1.290"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; pyridoxine 5'-phosphate biosynthesis; pyridoxine 5'-phosphate from D-erythrose 4-phosphate: step 2/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.290" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298226.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001532"/>
    <dbReference type="EnsemblBacteria" id="EEZ40506">
        <property type="protein sequence ID" value="EEZ40506"/>
        <property type="gene ID" value="VDA_001532"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0111">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1638924at2"/>
    <dbReference type="UniPathway" id="UPA00244">
        <property type="reaction ID" value="UER00310"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033711">
        <property type="term" value="F:4-phosphoerythronate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008615">
        <property type="term" value="P:pyridoxine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12158">
        <property type="entry name" value="ErythrP_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01825">
        <property type="entry name" value="PdxB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029753">
        <property type="entry name" value="D-isomer_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020921">
        <property type="entry name" value="Erythronate-4-P_DHase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024531">
        <property type="entry name" value="Erythronate-4-P_DHase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038251">
        <property type="entry name" value="PdxB_dimer_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11890">
        <property type="entry name" value="DUF3410"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00671">
        <property type="entry name" value="D_2_HYDROXYACID_DH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0520">NAD</keyword>
    <keyword evidence="2 5 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 5" id="KW-0664">Pyridoxine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2-Hacid_dh" evidence="7">
        <location>
            <begin position="4"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="2-Hacid_dh_C" evidence="8">
        <location>
            <begin position="110"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3410" evidence="9">
        <location>
            <begin position="294"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="209"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="242"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="259"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="237"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="262"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="263"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF11890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ40506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="394" mass="43315" checksum="98A48A4DE7A46A44" modified="2010-01-19" version="1">MKILIDENMPYAHELFSQLGEVIAKPGRSLMPADLVDIDALMIRSVTKVNRELLTQVNKLKFVGTATAGDDHVDQALLAEKGITFTAAPGCNKVGVAEYVISSLMVLGQQHGFSIFDKTVGIIGAGNVGTYLAQCLDALGIRYLLNDPLKQEQGDPRQFHTVDEILAQCDVITLHTPITRTSLYPTHHLVDSAFLAKMQNNAILINAARGPVVDNQALKQALIDSQQGEKTLTAVLDVFEQEPLVDLELLPLLAFATPHIAGYGLEGKARGTTMVFNAFCQFIGSQLYADAKELLPVAPIPYVQLSRIWDEASLFNLTQLIYDVRKDDGIFRFEMFKTGDDSSQMASAFDQMRKNYWDRREYSAITVAGEAAFAVESLAKLGFTVVEETHESGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX16</accession>
    <name>D0YX16_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Hypothetical major outer membrane protein OmpU</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001895</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell outer membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298890.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001895"/>
    <dbReference type="EnsemblBacteria" id="EEZ40863">
        <property type="protein sequence ID" value="EEZ40863"/>
        <property type="gene ID" value="VDA_001895"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1064531at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015288">
        <property type="term" value="F:porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00342">
        <property type="entry name" value="gram_neg_porins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033900">
        <property type="entry name" value="Gram_neg_porin_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13609">
        <property type="entry name" value="Porin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019783" evidence="3">
        <location>
            <begin position="21"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="domain" description="Porin_4" evidence="4">
        <location>
            <begin position="9"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="336" mass="37384" checksum="C7E63E5C8916C90B" modified="2010-01-19" version="1">MNIKFITLAVASSIAFPVSAATVYKDSNTDFEIGGRVEGRANFSDANKTSSNSSTYEDMSRVRLNVQGKQEYNQDISFVGRYEFELTEQTDPASDDEVDINTRHMYVGAETSMGNLYYGHQNNAVTYLTDWTDMAETYSGYTNEYTVASADRAKNVIRYAITTPEGITFQADGNFNSDSQSDGYGVALAYEVNNLGVGVGYSASDQTYSWKTNPNLKHDSDTYFIAAKYSFDGFYGAAMYQGGKIADSDFYAIDAFANYTFGDNMVDISYNKYSADDYVLLDIEFIGIEYARYMGNFAAYASYKFNLVDVASGYTSADYIGDNTDDELMLGVRYSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX38</accession>
    <name>D0YX38_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Vitamin B12-dependent ribonucleotide reductase</fullName>
            <ecNumber evidence="7">1.17.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_001894</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>[thioredoxin]-disulfide + a 2'-deoxyribonucleoside 5'-diphosphate + H2O = [thioredoxin]-dithiol + a ribonucleoside 5'-diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23252"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:73316"/>
            <dbReference type="EC" id="1.17.4.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 7">
            <name>adenosylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the ribonucleoside diphosphate reductase class-2 family.</text>
    </comment>
    <dbReference type="EC" id="1.17.4.1" evidence="7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298887.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001894"/>
    <dbReference type="EnsemblBacteria" id="EEZ40862">
        <property type="protein sequence ID" value="EEZ40862"/>
        <property type="gene ID" value="VDA_001894"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0209">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="357568at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004748">
        <property type="term" value="F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02888">
        <property type="entry name" value="RNR_II_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000788">
        <property type="entry name" value="RNR_lg_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013344">
        <property type="entry name" value="RNR_NrdJ/NrdZ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02867">
        <property type="entry name" value="Ribonuc_red_lgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01183">
        <property type="entry name" value="RIBORDTASEM1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02504">
        <property type="entry name" value="NrdJ_Z"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0846">Cobalamin</keyword>
    <keyword evidence="6 7" id="KW-0170">Cobalt</keyword>
    <keyword evidence="5 7" id="KW-0237">DNA synthesis</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RIBORED_LARGE" evidence="8">
        <location>
            <begin position="103"/>
            <end position="651"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ40862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="716" mass="80480" checksum="1205B8B2DDF75F2E" modified="2010-01-19" version="1">MAKSSLAADTTAKQTIPFQPTSIEIWNSKYRLKSKYGDAIDLTLDDTFKRVAKALSALEKPKLQQHWYQEFLWALRNGAIPAGRITSNAGAFEHKPATSTINCTVSGIIEDSMDDILAKVHEAGLTLKAGCGIGYDFSTLRPRGAFVSGAGAYTSGPLSFMDIYDKMCFTVSSAGGRRGAQMGTMDVRHPDIIEFIRAKREDGRLRQFNLSLLITEEFIEAVKQDLSWQLIFPMTAKEIAQDGIDVDNDETMVWADWPTTTDLIENDLGQVACKIYRTLPARNLWNIIMTSTYDYAEPGFILIDKVNQMNNNWFCEDIRATNPCGEQPLPPYGACLLGSVNLTKFVRYPFTEQAEFDWKEFRKVVAIFTRMLDNVVEINHLPLEKQRHEIENKRRHGMGFLGLGSTLTMLRHQYGSAASVAFTEQVALELAVVGWQQALELAKEKGSAPIMEQEFEVTAKMLRQRPEMHDDGYELGDKVKGRILHAKYSRYMQQLAEVEPELVTQLMETGARFTHHSSIAPTGTISLSLANNASNGIEPSFAHHYTRNVIVAGKKTKESVDVYSYELLAYRELINDKAMPYSTEPDAMLPDYFITADDITPSQHVEVQAAAQRWIDSSISKTANVPTNFAFESFKDIYMDAYDKGLKGCTTFRFNPEVFQGVLVKEKDLENTTYVFTLADGSTFEAKGNEQIEYDGEIHTAANLYDALKEGYYGKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX58</accession>
    <name>D0YX58_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">APH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001847</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298807.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001847"/>
    <dbReference type="EnsemblBacteria" id="EEZ40815">
        <property type="protein sequence ID" value="EEZ40815"/>
        <property type="gene ID" value="VDA_001847"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0510">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="APH" evidence="1">
        <location>
            <begin position="25"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="283" mass="32508" checksum="5A2DFE1EAC1AED02" modified="2010-01-19" version="1">MANKQFINGFDADIIPNFQITSAIPLSGGLTNRCWKLTGYYQGRLLTAVWRPVSAISQAFLVDRQQEFLTLQQLSASLAPLPIYCNNQGLLVEWLEGKEAGKETSDSEILELLVQIHQQPLPQTTLDLKQRCQYYWDQIPVELHSHRLLQLHSWFAHSVIPESKQLACCHCDLGRYNLIRKGSRLKVIDWEYAAAGDALLDLALTILANDMSIERAVTQYCQLTKSEFNVILTQVNTYLPWGMWLAILWYYIGYEQWQDSEYLNAALALQQELIQRLRLADDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX61</accession>
    <name>D0YX61_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001850</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001850"/>
    <dbReference type="EnsemblBacteria" id="EEZ40818">
        <property type="protein sequence ID" value="EEZ40818"/>
        <property type="gene ID" value="VDA_001850"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5032Y39">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="89" mass="8983" checksum="05F6A9A4851900AC" modified="2010-01-19" version="1">MISAEGGLESDDAEDVALSYDAVLTIGNNVNTFNAPGGFNTNNYTETYSLSGSATLAAGIAGQIELTTTAAAPWSGGYSDTLTVAITAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX95</accession>
    <name>D0YX95_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001954</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299007.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40922">
        <property type="protein sequence ID" value="EEZ40922"/>
        <property type="gene ID" value="VDA_001954"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3083">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1067869at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008484">
        <property type="term" value="F:sulfuric ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012159">
        <property type="entry name" value="YejM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024588">
        <property type="entry name" value="YejM_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11893">
        <property type="entry name" value="DUF3413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004950">
        <property type="entry name" value="Mmb_sulf_HI0842"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="160"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3413" evidence="3">
        <location>
            <begin position="14"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="2">
        <location>
            <begin position="249"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF11893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="604" mass="70047" checksum="0D4B28A51D9001CA" modified="2010-01-19" version="1">MFQCFLKNCRWLVAFWGCLTVFIALGFSSFLHNDNGQSYSLLQQCYLIFTQYGWFGLICLAFNLVLLPLGILPTHYFKVIIAIVFSILLLILNVDLVVFEQYKFHINALLIKMFFNAGNEVFDISWVSWLFFIGLYCFYLIGLGFVFWLSKRVLESKLKWILMISWFISLLLSQGIHAYSNALYSMEFSQFNNKWPLYYPLTAREFLYKNNIVNRNKAEKNRIQVHSLQATNILYPLHSVQIDSDIKKPNVLFIMIDAWRFSDATKSVMPNVSQFAQKTYRFQEHRSGGNSTQAGMFSLFYSLPPTYWDSFYASQTSPIFMNKIIESGYQTEILGSATLNSPPLGRTIFKEVKQLRLHTPGKNAVERDAQITQDFLTFLKNKRNDQPYFGFLFYDAAHASDFSADSSKFEPYVQRVDHALLNNNFDASLYHNRYKNSLVYIDKLIAQVLAKVNLKDTVIVITSDHGQEFNDNKQNYWGHSSNYSDVQIHVPLYVYLPEHNGQVINYRTNHYDIMPTLMSEIFHSPTSTSDYSVGYNLFDPKPRDWFIAGSYYNYAIVGPDAMLVTYPGGGYQSLDNHLKPINGSRIPIDVIKKQVDLMAKYYKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXC4</accession>
    <name>D0YXC4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Methionine--tRNA ligase</fullName>
            <ecNumber evidence="16">6.1.1.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Methionyl-tRNA synthetase</fullName>
            <shortName evidence="16">MetRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="primary">metG</name>
        <name evidence="20" type="ORF">VDA_001664</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 16">Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 16">
            <text>ATP + L-methionine + tRNA(Met) = AMP + diphosphate + L-methionyl-tRNA(Met)</text>
            <dbReference type="Rhea" id="RHEA:13481"/>
            <dbReference type="Rhea" id="RHEA-COMP:9667"/>
            <dbReference type="Rhea" id="RHEA-COMP:9698"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78530"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="16">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="16">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 16">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 16">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 16">Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.10" evidence="16"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298474.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001664"/>
    <dbReference type="EnsemblBacteria" id="EEZ40637">
        <property type="protein sequence ID" value="EEZ40637"/>
        <property type="gene ID" value="VDA_001664"/>
    </dbReference>
    <dbReference type="GeneID" id="57342254"/>
    <dbReference type="eggNOG" id="COG0073">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0143">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="761140at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004825">
        <property type="term" value="F:methionine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006431">
        <property type="term" value="P:methionyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07957">
        <property type="entry name" value="Anticodon_Ia_Met"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00814">
        <property type="entry name" value="MetRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02800">
        <property type="entry name" value="tRNA_bind_EcMetRS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00098">
        <property type="entry name" value="Met_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041872">
        <property type="entry name" value="Anticodon_Met"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004495">
        <property type="entry name" value="Met-tRNA-synth_bsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023458">
        <property type="entry name" value="Met-tRNA_ligase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014758">
        <property type="entry name" value="Met-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015413">
        <property type="entry name" value="Methionyl/Leucyl_tRNA_Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033911">
        <property type="entry name" value="MetRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029038">
        <property type="entry name" value="MetRS_Zn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002547">
        <property type="entry name" value="tRNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45765">
        <property type="entry name" value="PTHR45765"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19303">
        <property type="entry name" value="Anticodon_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09334">
        <property type="entry name" value="tRNA-synt_1g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01588">
        <property type="entry name" value="tRNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01041">
        <property type="entry name" value="TRNASYNTHMET"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57770">
        <property type="entry name" value="SSF57770"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00398">
        <property type="entry name" value="metG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00399">
        <property type="entry name" value="metG_C_term"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50886">
        <property type="entry name" value="TRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15 16 18" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="12 16 18" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 16" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 16 18" id="KW-0436">Ligase</keyword>
    <keyword evidence="9 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 16 18" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14 16 18" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13 16 17" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7 16 17" id="KW-0820">tRNA-binding</keyword>
    <keyword evidence="11 16" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="TRNA-binding" evidence="19">
        <location>
            <begin position="581"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="16">
        <location>
            <begin position="15"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="16">
        <location>
            <begin position="332"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="335"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU363039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="EEZ40637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="682" mass="76984" checksum="320CA337CAF29BD4" modified="2010-01-19" version="1">MAANPRKILVTCALPYANGSIHLGHMLEHVQADIWVRYQRLRGNEVHFICADDAHGTPIMLKAQQMGMEPEQMIAEVSKEHQADFAGFDIDFSNYHSTHSPENRELASFVYNQLKQQGYITSRTISQLFDPEKEMFLPDRFVKGTCPKCGAEDQYGDNCDNCGETYSPTDLINPKSAVSGATPVMKDSEHFFFDLPQFESMLKEWTKSGALQDETANKMQEWFESGLQQWDISRDAPYFGFEIPGETGKYFYVWLDAPIGYMGSFKNLCDKRDDLDFDEFWNKDSSTELYHFIGKDIVYFHSLFWPAMLDGAGFRKPNNVFVHGYVTVNGAKMSKSKGTFIKAGTYLQHLDPECLRYYYAAKLNSRIDDLDLNLEDFTQRVNSDVVNKIVNLASRNAGFIAKRFDGKLAERCAEPELYAEFVAAADRIGALYESREYGRAIREITALADKANQYVDEKAPWVVAKEEGKDLELQEICSMGINLFRVLMAYLKPVMPKLAERTEAFLNETLTWEGIAQPLTAHEVTKFKALFNRIDPKNVEAMIETSKADAAAEMAAKEQAEAAQQTELSKEPIEPEIEFDDFAKIDLRIAKIISCESVPKADKLLKFQLDIGGETRQVFSGIKAAYNPEDLVGKLTVVVANLKPRKMKFGMSEGMILAAGPGGKDLWILEPHEGAQPGMRVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXJ5</accession>
    <name>D0YXJ5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001709</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298554.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001709"/>
    <dbReference type="EnsemblBacteria" id="EEZ40680">
        <property type="protein sequence ID" value="EEZ40680"/>
        <property type="gene ID" value="VDA_001709"/>
    </dbReference>
    <dbReference type="GeneID" id="57342206"/>
    <dbReference type="eggNOG" id="COG4006">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1425664at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015093">
        <property type="entry name" value="DUF1887"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09002">
        <property type="entry name" value="DUF1887"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="388" mass="44422" checksum="A27DF58A4C08E9B2" modified="2010-01-19" version="1">MITHVGIIDQDPVRLITPLLDHGVPADKMIFIGIENQYEQYERLASILTPRNIEVEFFEVPDVINIAAIRGRLEELAARLKDTSGEIWFNASCGLRHRLLSAYEVFRTFHWPIYVIEPYSDEMCWLYPSDREQQQVEDRIQLTDYLTIFGARSELPEHNIPDSLNEQLWELGQRWASSALELGPGLATLNYLATTCRKEQKLDVELSEKQQGYKELGTLIADLEETGMAHYHEGILTFKHEEARRFANGEWLENLVHLTVRAIQNELPTIQDHSLGVQVYRKIGDREVRNELDVATIVNNKLHIIECKTKGMREDGDDTLYKLESLRDLLGGLQARAMLVSFRPLRHHDLVRAQDLGLAIIGPDQLGDLQTHLYEWLKGAGGQAHNIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXL1</accession>
    <name>D0YXL1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidase_M15_4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001726</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001726"/>
    <dbReference type="EnsemblBacteria" id="EEZ40696">
        <property type="protein sequence ID" value="EEZ40696"/>
        <property type="gene ID" value="VDA_001726"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2843">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009045">
        <property type="entry name" value="Hedgehog_sig/DD-Pept_Zn-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039561">
        <property type="entry name" value="Peptidase_M15C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13539">
        <property type="entry name" value="Peptidase_M15_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55166">
        <property type="entry name" value="SSF55166"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018706" description="Peptidase_M15_4 domain-containing protein" evidence="1">
        <location>
            <begin position="25"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M15_4" evidence="2">
        <location>
            <begin position="131"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="306" mass="34529" checksum="A02585CEEDADFE72" modified="2010-01-19" version="1">MMNKHYISLGVIVGVACFTGNVSAATVTAISNEQCLAMKNVGVMSPSAPVSCQRLKLVTFNYRDFSGHKHSNGKIIVMDAVAPYVGKIFDELYQQGFPIHKAEPIEKYRGDDTKSMVANNTSAFNYRPVEGTSSLSLHAYGAAIDLNPVQNPFVTFPRTGQAKYSPVEGTKYANREIYRYGKPDRQGMAETVVDIFARNGFLYWGGFWNSPIDYQHFQLSKDMAIMMSKMTEQQATLFFQHYVDWYNSCSRMYPKAYSQYKFNDYTNYLKHKLGVSSLNKAYSANSAKVLAEIEKQPVRSSLCVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXN5</accession>
    <name>D0YXN5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Endo/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001734</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001734"/>
    <dbReference type="EnsemblBacteria" id="EEZ40702">
        <property type="protein sequence ID" value="EEZ40702"/>
        <property type="gene ID" value="VDA_001734"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4222">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endo/exonuclease/phosphatase" evidence="1">
        <location>
            <begin position="15"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="356" mass="39736" checksum="5EDAC14D736F9F7F" modified="2010-01-19" version="1">MSADSETAILEQTATLDSLRFKKIAATIQSVRPDVLLLCEFDHLGEGGDNGALQNFCRHYLNRFQYDLSPIHYPYSYCPSSNTGKLSPVDLNNDGIISLPEDGLGFGLFHGHYGFVLLSKYPIKTDEIQSWQTLLWQQVPNSLLPTQYYSPQAQSVLPLSSKNHVCVPIEYDEQIINILCCHPTPPVFDGEERRNAKRNHDELRLLVDIIDGADYLVSDQGQTSGINLQQPFVVMGDLNADPIDGDGIKAGIDALLNHPLIEKSVATGAKVPASLGGKYKRVYQKRNGKPDIWTHVSGLRLDYVLPSTHCHIQNSGVFWPDKKDPKRVWITNHSGKETSAAYSDHRLVWVDVTISK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXW8</accession>
    <name>D0YXW8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Short chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002131</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299507.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002131"/>
    <dbReference type="EnsemblBacteria" id="EEZ41099">
        <property type="protein sequence ID" value="EEZ41099"/>
        <property type="gene ID" value="VDA_002131"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0300">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3320">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1928091at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013120">
        <property type="entry name" value="Far_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07993">
        <property type="entry name" value="NAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD_binding_4" evidence="2">
        <location>
            <begin position="5"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="630"/>
            <end position="649"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="663" mass="74104" checksum="4038684A7A5802DE" modified="2010-01-19" version="1">MNYFITGATGFIGSHLLARLAKRSGNFYLLARSDNAEQKLQLLIEKHQLPADRFHLVTGSITETNLGLSSKTISELTGKITHFYHLAAIYDLEADEEALKRANIEGTENCVRMAERLQAKCFHHVSSIAVAGQFRGWFREDMLDQATGLDHPYFSTKHESEKIVQQSCTIPWRVYRPGIVVGHSKTGEAERIDGPYYFFKIIQKLRQALPEWMPLLGLEGGRLNIVPVDYVADTIDHISHLEDLDQQCFHVVDPDPYRAGEVINLFAQAGHAPRMAMRFDMRLLNMVPSHLWKQLAHLPVLERFIDAISQEIRVPKDALSMFNYPTQFDCTNTLQALEGSNITCPRLSEYAAPIWDYWERNLDPDLHVEKSLKGCVAGKVIAITGASSGIGYTTAIKLAKTDAKLVLIARDLERLQQTRNEIERLGGHAAIYQCDLSKDEPAQETLELIKQHHGSIDILINNAGRSIRRSVVNSVDRLHDYERTMQINYFGALRMIMGTLPGMLEKEAGHIINISSIAVLTNQPRFSAYAASKAALDSFTRTAGAELCGQGVHFTTINMPLVETPMIADHYRQAKGGIPLLTSEEAADLIIKAIIEKPKRIATKLGLFAALVHGVYPKLGELVMNAGFNISPDSDDPERDSQQPKEHTPDVVALSSLIREIHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXW9</accession>
    <name>D0YXW9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002132</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299509.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002132"/>
    <dbReference type="EnsemblBacteria" id="EEZ41100">
        <property type="protein sequence ID" value="EEZ41100"/>
        <property type="gene ID" value="VDA_002132"/>
    </dbReference>
    <dbReference type="GeneID" id="57341737"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023772">
        <property type="entry name" value="DNA-bd_HTH_TetR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025722">
        <property type="entry name" value="TetR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13972">
        <property type="entry name" value="TetR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01081">
        <property type="entry name" value="HTH_TETR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="24"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="210" mass="24703" checksum="DB2CEE641EBED418" modified="2010-01-19" version="1">MKTRDRILAVSLDLFNRHGVSQVSTLIIATEMGISPGNLYYHFRGKEEIISTMISDLQHAITQLSAEYPNQVKEFDDYWPFMHTVMALFTHYRFLFRNLDNLNSQDQQMRRKIRSLVLKLRQITTDMINHLIELEKIRCDKQTVPLLADNLLLVSLNWLNYQTLLDDKYSDEELIRTGVLRIISLLEPYLTENAQSPYFTHQDLLNELVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY06</accession>
    <name>D0YY06_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphatidylglycerophosphatase B</fullName>
            <ecNumber evidence="3">3.1.3.27</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002169</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.3.27" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002169"/>
    <dbReference type="EnsemblBacteria" id="EEZ41137">
        <property type="protein sequence ID" value="EEZ41137"/>
        <property type="gene ID" value="VDA_002169"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0671">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1928533at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008962">
        <property type="term" value="F:phosphatidylglycerophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="P_Acid_Pase_2/haloperoxi_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="P_Acid_Pase_2/haloperoxidase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00014">
        <property type="entry name" value="acidPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="SSF48317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="160"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="187"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="acidPPc" evidence="2">
        <location>
            <begin position="82"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="237" mass="26961" checksum="8B89C2E33E3AEA15" modified="2010-01-19" version="1">MISSYIYKKYPNIIALACFSVAMIAAMFIFPAPELTSHLSDTLGLIFTILTESAGKPFFLVTIALLCFIPIVMRLPRKTMVKLWIQFAIILVLSLVAKTALKHFTAVPRPFTHELQQLHVIDQPQDFYQLSKEDKALTVAKVDDQVSHWRTDLWKKKESYSFPSGHTIFVAVCVMFWGGFFIRRRKYVPAAIIITWATGVGLSRLWLGMHWPADLLGSMSAAAILYLFVPEWDETES</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY24</accession>
    <name>D0YY24_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cyclic-guanylate-specific phosphodiesterase</fullName>
            <ecNumber evidence="3">3.1.4.52</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">VDA_002187</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>cyclic di-3',5'-guanylate + H2O = 5'-phosphoguanylyl(3'-&gt;5')guanosine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24902"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58754"/>
            <dbReference type="ChEBI" id="CHEBI:58805"/>
            <dbReference type="EC" id="3.1.4.52"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="3.1.4.52" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299612.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002187"/>
    <dbReference type="EnsemblBacteria" id="EEZ41155">
        <property type="protein sequence ID" value="EEZ41155"/>
        <property type="gene ID" value="VDA_002187"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2200">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071111">
        <property type="term" value="F:cyclic-guanylate-specific phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024744">
        <property type="entry name" value="CSS-motif_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12792">
        <property type="entry name" value="CSS-motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0973">c-di-GMP</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="11">
        <location>
            <begin position="249"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ41155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="511" mass="59348" checksum="E7C85D20F95C6662" modified="2010-01-19" version="1">MSKSKTILLFICSVIIGLAVNLIWIRFQVNHQTEEMLSTIDTATTQYLNRMTNEIKFLHSTAPICSETFINHLESTVLKSMSIQEITYINKNQFICSDRGMQEQAQTINIEQLNKYKDNNGYIIYRGRSLRYDIDGLYIMLPVAKQTWYRFLINDAFLKFWLEQHLLDKHIHACVNSLGQTIVCTGPHESQYQHTYHRYSENYNLHFTASFDNEIYWCYFKYNLPYTIILLTIFSSLCLVLAHNYYHRRQSLSAEIQRGIDNHEFIGYYQPIISAKNNRWCGAELLVRWNHPKAGLIPPDQFIHIAERSELIHQMTLDLIKQIALQKTYIEQLVPHSYFSINMTPSMIANTQFVTKLVQILQMNPDLQHGLVIELTEREPFSPAKLLKLKQGMDLLRSYGVKWALDDFGTGYSGLATLQQLSFDILKIDRTFINLSSNDAISLSILDNIAQMGHKLHCSLVAEGVETKEQAQYAKKIGIEACQGYYYAKPMTFDDYYHALKNHLGNRFIPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY49</accession>
    <name>D0YY49_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Quinone-reactive Ni/Fe hydrogenase cytochrome b subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_002212</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HupC/HyaC/HydC family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299658.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002212"/>
    <dbReference type="EnsemblBacteria" id="EEZ41180">
        <property type="protein sequence ID" value="EEZ41180"/>
        <property type="gene ID" value="VDA_002212"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1969">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="923657at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011577">
        <property type="entry name" value="Cyt_b561_bac/Ni-Hgenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016174">
        <property type="entry name" value="Di-haem_cyt_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000516">
        <property type="entry name" value="Ni-dep_Hydgase_cyt-B"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01292">
        <property type="entry name" value="Ni_hydr_CYTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00161">
        <property type="entry name" value="NIHGNASECYTB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81342">
        <property type="entry name" value="SSF81342"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02125">
        <property type="entry name" value="CytB-hydogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00882">
        <property type="entry name" value="NI_HGENASE_CYTB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="64"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="182"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="Ni_hydr_CYTB" evidence="5">
        <location>
            <begin position="14"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="234" mass="27045" checksum="AFB3124308A679A5" modified="2010-01-19" version="1">MANDTVLYKRSYMFSFLIRVCHWLRALSIVGLVITGFYIAWPFLVRPESTNVLQQGWIRFAHEIFGFLLLAITAVRFYLFFFSQKSKAERMSFKDAFSIKSWIQQFKAYFFVGLPPHRGAYGPLQLVAYAGISVVAVFMCITGLTLYANVYHQGIGGMLWPMAEWVTYIMGGLAEVRQWHHIMTWAFIIFVLGHVYMVIWTGIRFRTGSADAIMSGYAYHPVHVKPEDVEEEKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY91</accession>
    <name>D0YY91_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Chitodextrinase</fullName>
            <ecNumber evidence="6">3.2.1.14</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_002254</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.2.1.14" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002254"/>
    <dbReference type="EnsemblBacteria" id="EEZ41222">
        <property type="protein sequence ID" value="EEZ41222"/>
        <property type="gene ID" value="VDA_002254"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3325">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3693">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004568">
        <property type="term" value="F:chitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032798">
        <property type="entry name" value="CBM_5_12_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003610">
        <property type="entry name" value="CBM_fam5/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036573">
        <property type="entry name" value="CBM_sf_5/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009470">
        <property type="entry name" value="Chi_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14600">
        <property type="entry name" value="CBM_5_12_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06483">
        <property type="entry name" value="ChiC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00495">
        <property type="entry name" value="ChtBD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51055">
        <property type="entry name" value="SSF51055"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54556">
        <property type="entry name" value="SSF54556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2 4 6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1 4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GH18" evidence="5">
        <location>
            <begin position="1"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="674" mass="72639" checksum="3061924D23B44C51" modified="2010-01-19" version="1">MEWDGVEIDPALGFKGHFGALATAKVKHDVKTLISIGGWAETGGHFDTNGDRVADGGFYTMTTNADGSINHAGIEKFAASAVEMMRKYKFDGLDIDYEYPTSMAGAGNPYDKEFMEPRRPYLWASYQELMKVLREKLDAASAQDGIHYMLTIAAPSSGYLLRGMETFDVTQYLDYVNIMSYDLHGAWNDHVGHNAALFDTGKDSELAAWNVYGTAAYGGIGYLNTDWAYHYFRGSMPAGRINIGVPYYTRGWQGVTGGENGLWGKAPLPNQSECAPGTGEGEKNNCGYGAIGIDNMWHDLDPQGKEMGAGSNPMWHAKNLEHGVFGSYAAAYGLDPANDPDDKLVGTYSRNYDSVAVAPWLWNAEKSVFLSTEDKASVSVKADYIIDKEIGGIMFWELAGDYSCYLLDDNGKRTATIDATEKACASGNGEYHMGNTMTKAIYEKFKSASPYGNTVATGAIPTEAADIAVSVGGFKVGDQNYPINPKITFTNNTGVDLPGGTEFQFDIPTSAPDNAKDQSGGGLKVIASGHTKANNIGGLEGVMHRVAFTLPKWKSLPAGESYELDMVYYLPITGPANYVVIVNGKEYAFKFEQPDLPLGDLTTGGGEGGGGDGGTCDTAGVNTYPDWPQADWAGNPSHANTGDQLIYNGVIYKANWWTSSVPGSDGSWSKVCKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYA8</accession>
    <name>D0YYA8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulators LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002271</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299766.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002271"/>
    <dbReference type="EnsemblBacteria" id="EEZ41239">
        <property type="protein sequence ID" value="EEZ41239"/>
        <property type="gene ID" value="VDA_002271"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="1">
        <location>
            <begin position="4"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="300" mass="34178" checksum="7830E5E501DE6725" modified="2010-01-19" version="1">MKKFTFEQVDAFVAVVEAGSFSAAARRLRKDKSSIHQLVSYLEIELGIELFNREKKLPILRPEAKNIYNYSKLLLEQHKEIQSLADNLFHGIEDSLTISYDIVIPRRIIADISAQLSKEYPSSQIHWLCQNKAMAIHALDNQSIDITLQALSHRAKPQDGLEALTLGQVACSLYVNKNTVDQNQSYTRSYLQVKPQFILESFVAAELDELAILSPFYRLFTEVYLMIECMSQTPHSWAIIPDHLAEPFVDNKLTKLKDSGFSAQEVLWPCVMLTNQKGVKGPVFQRASELIIEKMRGFDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYB9</accession>
    <name>D0YYB9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002282</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299783.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41250">
        <property type="protein sequence ID" value="EEZ41250"/>
        <property type="gene ID" value="VDA_002282"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5032RUG">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1896101at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021724">
        <property type="entry name" value="DUF3297"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11730">
        <property type="entry name" value="DUF3297"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="82" mass="9445" checksum="1357B379DE777635" modified="2010-01-19" version="1">MNDNQARPELPDHLSGNPRSPHHVAECFEHEIGIIFNDKERFDVEEYCVSEGWIKIPSPKALDRRGQPILVTLKGKVEAFYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYL5</accession>
    <name>D0YYL5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Aromatic amino acid permease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">VDA_002378</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Involved in transporting aromatic amino acids across the cytoplasmic membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Cell inner membrane</location>
            <topology evidence="2 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the amino acid/polyamine transporter 2 family. Mtr/TnaB/TyrP permease subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299987.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002378"/>
    <dbReference type="EnsemblBacteria" id="EEZ41346">
        <property type="protein sequence ID" value="EEZ41346"/>
        <property type="gene ID" value="VDA_002378"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="935253at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015173">
        <property type="term" value="F:aromatic amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018227">
        <property type="entry name" value="Amino_acid_transport_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013061">
        <property type="entry name" value="Trp/try_permease_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013059">
        <property type="entry name" value="Trp_tyr_transpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46997">
        <property type="entry name" value="PTHR46997"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03222">
        <property type="entry name" value="Trp_Tyr_perm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00166">
        <property type="entry name" value="AROAAPRMEASE"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00837">
        <property type="entry name" value="araaP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00594">
        <property type="entry name" value="AROMATIC_AA_PERMEASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="6 10" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="34"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="82"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="144"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="177"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="217"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="273"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="307"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="332"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="377"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU367149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ41346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="405" mass="43437" checksum="24AA47E1F38AC8AF" modified="2010-01-19" version="1">MSFNKTFGSMLIIAGTTIGAGMLALPLASAGLGFTTSILIMIGMWALMSYTALLMLEVHQYADKSATLHTLAYKLLGRKGQVIASGAMLFLFYALCAAYIAGGGAQLHQKIQSLHVDIAPQIATVVFTFVIASVVAIGTHSVDIVNRVLFTAKIIAMAVMLALLLPQVKSHNLLEMPMQQGLIISALPVVFTSFGFHGSIPSIVRYLGLNIPNLKKVMIFGSALPLIVYLLWQLATQGILSQSELLANTDLTQFINALSQRLHNPLVGQSVSLFADLALATSFLGVSLGLFDFLADTLRRKATLAGRVQTACVTFIPPLAFALFYPQGFIMALGYAAIALVILAIFLPVAMVWQQRKQKATSTQENTSDYQVMGGKLSLITVIVIGVIIILSQLLQIVGIIPKLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYP3</accession>
    <name>D0YYP3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">N-acetylglucosamine regulated methyl-accepting chemotaxis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">VDA_002406</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300032.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002406"/>
    <dbReference type="EnsemblBacteria" id="EEZ41374">
        <property type="protein sequence ID" value="EEZ41374"/>
        <property type="gene ID" value="VDA_002406"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0840">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4564">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="429006at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004090">
        <property type="entry name" value="Chemotax_Me-accpt_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033480">
        <property type="entry name" value="sCache_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17200">
        <property type="entry name" value="sCache_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00260">
        <property type="entry name" value="CHEMTRNSDUCR"/>
    </dbReference>
    <dbReference type="SMART" id="SM01049">
        <property type="entry name" value="Cache_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0807">Transducer</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="10">
        <location>
            <begin position="267"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="311"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ41374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="541" mass="58847" checksum="3E13571A74B648DB" modified="2010-01-19" version="1">MKLKTQAYVLALITLVGFLALTATGLWTLRVASNLDNKSRVTEIFTSTYNMLTEIEKMVQDGVLPETTAKEMATRMLRNNIYKDNEYVYVADNNMIFIAAPLDPQLHGTSFNDFKTSDGDSVGQLIQQKLAGRTGQLIEYTWDQRQPDGSVEEKLSIAEKTHVWGWVVGTGIGFNEVNARFWSTAQFQLLLCLAIAGSILALLIFSVRRIIALVGGEPVEVCAAVQAVANGEIQTYFAESAPQGSIYHAVQNMSLSLAQLVNNLEQSISGLRKELADVESFSDGINQLTNEQQQSTSMIATAVTEMVSSAQNVSDSASDTARYTDEADSQSKQTQHTLYATVENVQGLATQLGMASKAVEDLDQDVNNIVKILDVIGGIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRNLAGRTKDSTIEIQQMITNLQNGSRNAIETMGMCAETSRKTEDESQSAAVALEQIVIALESISAMSQQIATAAAEQTQVSNDIAHRIHLIEDNSNQLNHAVNESNNSTQKLSTLANELETWAHKFKVKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYR5</accession>
    <name>D0YYR5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Histidine kinase</fullName>
            <ecNumber evidence="3">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">VDA_002428</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002428"/>
    <dbReference type="EnsemblBacteria" id="EEZ41396">
        <property type="protein sequence ID" value="EEZ41396"/>
        <property type="gene ID" value="VDA_002428"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3275">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010559">
        <property type="entry name" value="Sig_transdc_His_kin_internal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011620">
        <property type="entry name" value="Sig_transdc_His_kinase_LytS_TM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07694">
        <property type="entry name" value="5TM-5TMR_LYT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06580">
        <property type="entry name" value="His_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="10" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="77"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="112"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="167"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="HATPase_c" evidence="13">
        <location>
            <begin position="448"/>
            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEZ41396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="548" mass="60927" checksum="0CF9C262C9DB8210" modified="2010-01-19" version="1">MYSEQLMMLLAVFERAALMLMALFLLTRTPLFQDIVKKKHRRPIETAMISLLFILFAVFSTYTGVKVDGSLVNVRIIAVISGGIIFGPWIGIPAGIIAGIHRYLIDIDGPTSVACLITSVIAGLLATWIHKKCAPKHYAKLGILAGMVCEALTMTLIVVLSNNDSQAYTIVSHISFPMITGTLCIGLIIKLVQDLDEEKDLVAARQAKLALDIANKTLPYFRKSNRESLMAVCNIIRHETEADAVSITDTQDVLAYVGIGEENYLDAYHKISTMTQQAVTTGQQIISNNLNIHNFHSLLIIPLCENGEVTGTLKIFYRQPNQVKPSLREMAIGLSQLISTQMEVSRIDQLRTMASKAEFSALQSKINPHFLFNALNAISTLVRIRPDQARELIANLADFLRYNLDHTDELIDIQEELQQVKDYVAIEQARFGNKLSVNFDIDDVHNKIPALLLQPLVENAILHGIQPSAKPGQVSILVKRLLTDEVQVTIEDTGVGIKPEVITKLRNGNMESHRIGLQNVHQRLLLLYGEGLEIVSDKHGTKMSFIIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYZ8</accession>
    <name>D0YYZ8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ferric uptake regulation protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">fur</name>
        <name evidence="4" type="ORF">VDA_002511</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the Fur family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300226.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="SMR" id="D0YYZ8"/>
    <dbReference type="STRING" id="675817.VDA_002511"/>
    <dbReference type="EnsemblBacteria" id="EEZ41479">
        <property type="protein sequence ID" value="EEZ41479"/>
        <property type="gene ID" value="VDA_002511"/>
    </dbReference>
    <dbReference type="GeneID" id="57341260"/>
    <dbReference type="eggNOG" id="COG0735">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1630127at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07153">
        <property type="entry name" value="Fur_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002481">
        <property type="entry name" value="FUR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043135">
        <property type="entry name" value="Fur_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33202">
        <property type="entry name" value="PTHR33202"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01475">
        <property type="entry name" value="FUR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0678">Repressor</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2 3" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU364037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="148" mass="16849" checksum="AF298E32C7087DD3" modified="2010-01-19" version="1">MSDNNHALKQAGLKITLPRLKILEVLQQPECQHISAEDLYKKLIDIGEEIGLATVYRVLNQFDDAGIVTRHHFEGGKSVFELATQHHHDHLVCLDCGKVIEFSDELIERRQKEIAAQYNVDLTNHSLYLYGHCANGDCCKDESLHDQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ22</accession>
    <name>D0YZ22_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Primosomal replication protein N prime prime</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002535</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300276.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002535"/>
    <dbReference type="EnsemblBacteria" id="EEZ41503">
        <property type="protein sequence ID" value="EEZ41503"/>
        <property type="gene ID" value="VDA_002535"/>
    </dbReference>
    <dbReference type="GeneID" id="57341234"/>
    <dbReference type="eggNOG" id="COG3923">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2011382at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038338">
        <property type="entry name" value="PriB/PriC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010890">
        <property type="entry name" value="Primosomal_replicat_PriB/PriC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07445">
        <property type="entry name" value="PriC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="183" mass="21705" checksum="C8A6AF01FB3A7A5B" modified="2010-01-19" version="1">MIDLTRFDTLIAQLKTQAANLDRTRGEANKPLFDEQLFRCRSKLLTPCVNEIASEVFKLRQEQQSGRLLPTRTQHICEKIVAQIQAVQREFATISIRKNEPKYRSAHYQPLNEIYQNLNQHKDWERQLKTKLRDKEFELSQCSDWQLQQKLQHEVLVLEGRVSRCQQALTKIEQTIMKRERKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ52</accession>
    <name>D0YZ52_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">3-ketoacyl-CoA thiolase</fullName>
            <ecNumber evidence="8">2.3.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">ACSs</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Acetyl-CoA acyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Acyl-CoA ligase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Beta-ketothiolase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Fatty acid oxidation complex subunit beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">fadI</name>
        <name evidence="13" type="ORF">VDA_002565</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>acetyl-CoA + an acyl-CoA = a 3-oxoacyl-CoA + CoA</text>
            <dbReference type="Rhea" id="RHEA:21564"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
            <dbReference type="EC" id="2.3.1.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Lipid metabolism; fatty acid beta-oxidation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Heterotetramer of two alpha chains (FadJ) and two beta chains (FadI).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8 10">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.16" evidence="8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300342.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002565"/>
    <dbReference type="EnsemblBacteria" id="EEZ41533">
        <property type="protein sequence ID" value="EEZ41533"/>
        <property type="gene ID" value="VDA_002565"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0183">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="330994at2"/>
    <dbReference type="UniPathway" id="UPA00659"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003988">
        <property type="term" value="F:acetyl-CoA C-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01618">
        <property type="entry name" value="FadI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012806">
        <property type="entry name" value="Ac-CoA_C-AcTrfase_FadI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020615">
        <property type="entry name" value="Thiolase_acyl_enz_int_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020613">
        <property type="entry name" value="Thiolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02446">
        <property type="entry name" value="FadI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00098">
        <property type="entry name" value="THIOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00737">
        <property type="entry name" value="THIOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 8" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5 8" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="6 8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase_N" evidence="11">
        <location>
            <begin position="15"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase_C" evidence="12">
        <location>
            <begin position="296"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="8 9">
        <location>
            <position position="99"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8 9">
        <location>
            <position position="392"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8 9">
        <location>
            <position position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000429-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ41533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="436" mass="46499" checksum="69047A7BA5C45B0B" modified="2010-01-19" version="1">MTRLQNLKTAQGERIAVVSGLRTPFARQSTAFAQVPAVDLGKLVVNEMLQRLDFDPKLIDQLVFGQVVQMPEAPNIAREIVLGTGMNVHTDAYSVTRACATSFQAVANVTESILSGSIEIGIAGGADSSSVLPISVSKKMAATLLALSKAKTMGQRAKLFSQLSLKDLMPVPPAVAEYSTGLSMGQTAEQMAKTHQITRQEQDALAHRSHTLAAQAWHDGLIRDEVMTAFPEPYRAWIDKDNNIREDSSLESYAKLRPAFDRKYGSVTAANATPLTDGAAAVLLMSEGRAKALGLTPLGYIRSYAFAAIGVEKDMLMGPSYATPLALDRAGISLSDLTLIDMHEAFAAQTLANVKMFGSAQFARDKLGRDHAIGEIDMDKFNVLGGSIAYGHPFAATGARMITQTLRELQRRGGGLALNTACAAGGLGAAMILEAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZP1</accession>
    <name>D0YZP1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Selenocysteine-specific translation elongation factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_002754</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300911.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002754"/>
    <dbReference type="EnsemblBacteria" id="EEZ41722">
        <property type="protein sequence ID" value="EEZ41722"/>
        <property type="gene ID" value="VDA_002754"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3276">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="244339at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001514">
        <property type="term" value="P:selenocysteine incorporation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015190">
        <property type="entry name" value="Elong_fac_SelB-wing-hlx_typ-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015191">
        <property type="entry name" value="Elong_fac_SelB-wing-hlx_typ-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004535">
        <property type="entry name" value="Transl_elong_SelB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09106">
        <property type="entry name" value="SelB-wing_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09107">
        <property type="entry name" value="SelB-wing_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="SSF50465"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00475">
        <property type="entry name" value="selB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="3">
        <location>
            <begin position="1"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="639" mass="72302" checksum="A97906B7FC47FEB1" modified="2010-01-19" version="1">MIIVTAGHVDHGKTHLLHALTGTNTDRLPEEQKRGLTIDLGYAFMPYQDQNNHQQTLGFIDVPGHEKFLSNMLAGVGTAHHALFIVAADEGLMAQSYEHLTILRLLNMDSLTVVITKSDLVDPTTLQLRINQVENALAMQNITQWHTFTCSAITGEGIDDLKQHLVTMANTEQQKQVVGKGFRLAIDRAFSVKGAGLVVTGTALNGQVKVGDTLYYVTHNPHHGGVESEPIKVRGLHAQGQEALTAQADQRIALNISGNIDKNQVSRGDWLVAIKPEQTVKRITATIQVHQPIKHWQSVQCFHAASHTMAKVALLEQESAIAGETILAELQFEQPLALCEQDKLLLRDPAQKHNLASAVAIDLAPPNRGKRKPERIAYLQKRSTLQQPEAILKHLLHHHPVDSRTFAWQHQIHSAQLTQLLPQDETIQQAGLYLFSANYQCQLQQQIVTQLERFHQKSCDEIGVGKARLYRMSALNQPQDIFEQVLAQLLLNGEISNTRGWLHLANHQLTLTEQEQQLWLAIEARMNQDLNPHWIRDLATEFDLAEENIRQLSYKLAQLGYLSAIVKDRYCTYQQLHTMADLTREHIAQYEKVETAEFRTLTQLGRKVAIQILEYFDRIGFTKRKFNYRQLRDSELLKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZQ8</accession>
    <name>D0YZQ8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">Chaperone protein DnaK</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">HSP70</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Heat shock 70 kDa protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Heat shock protein 70</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">dnaK</name>
        <name evidence="10" type="ORF">VDA_002771</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Acts as a chaperone.</text>
    </comment>
    <comment type="induction">
        <text evidence="7">By stress conditions e.g. heat shock.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300958.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002771"/>
    <dbReference type="EnsemblBacteria" id="EEZ41739">
        <property type="protein sequence ID" value="EEZ41739"/>
        <property type="gene ID" value="VDA_002771"/>
    </dbReference>
    <dbReference type="GeneID" id="57340951"/>
    <dbReference type="eggNOG" id="COG0443">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="161217at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00332">
        <property type="entry name" value="DnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012725">
        <property type="entry name" value="Chaperone_DnaK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="PTHR19375"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="SSF100920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="SSF100934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02350">
        <property type="entry name" value="prok_dnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword evidence="5 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="604"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="604"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphothreonine; by autocatalysis" evidence="7">
        <location>
            <position position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ41739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="638" mass="68847" checksum="761CEACA72DC3742" modified="2010-01-19" version="1">MGKIIGIDLGTTNSCVAVLDGDKPRVIENAEGERTTASVIAYAQDGEILVGQPAKRQAVTNPENTLFAIKRLIGRRFEDEEVQRDISIMPYKIVKADNGDAWVEAKGQKMAAPQVSAEVLKKMKKTAEDFLGEEVTGAVITVPAYFNDAQRQATKDAGRIAGLDVKRIINEPTAAALAYGLDKKGGDRTIAVYDLGGGTFDISIIEIDEVEGEKTFEVLATNGDTHLGGEDFDTRMINYLVDEFKKEQGIDLKNDPLAMQRLKEAAEKAKIELSSAQQTDVNLPYITADATGPKHMNIKVTRAKLESLVEDLVQRSLEPLKVALADADLSVGDINDVILVGGQTRMPLVQAKVAEFFGKEARKDVNPDEAVAVGAAIQGGVLAGDVKDVLLLDVTPLSLGIETMGGVMTKLIEKNTTIPTKASQVFSTAEDNQNAVTIHVLQGERKQAGYNKSLGQFNLEGIQAAPRGMPQIEVTFDLDADGILNVSAKDKNTGKEQKITIQASGGLSDEEIEKMVQEAEANKEADKKFEDLVAARNQADQLVHGTRKQIEEAGDALPADEKAKIEAAVSELEEARKGEDKEAIDAKVQALIAASQKLMEIAQQQAQAQQAGAGEQQAQQQDDNVVDAEFEEVKDDKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZS3</accession>
    <name>D0YZS3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Type I restriction-modification system specificity subunit S</fullName>
            <ecNumber evidence="5">3.1.21.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_002786</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-I restriction system S methylase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.21.3" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301004.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002786"/>
    <dbReference type="EnsemblBacteria" id="EEZ41754">
        <property type="protein sequence ID" value="EEZ41754"/>
        <property type="gene ID" value="VDA_002786"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0732">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="827072at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009035">
        <property type="term" value="F:type I site-specific deoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.220.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000055">
        <property type="entry name" value="Restrct_endonuc_typeI_TRD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044946">
        <property type="entry name" value="Restrct_endonuc_typeI_TRD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01420">
        <property type="entry name" value="Methylase_S"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0680">Restriction system</keyword>
    <feature type="domain" description="Methylase_S" evidence="4">
        <location>
            <begin position="1"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="Methylase_S" evidence="4">
        <location>
            <begin position="249"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="418" mass="46726" checksum="CBCAE78B7C7C92EB" modified="2010-01-19" version="1">MSDFEWVQLGKIAAITMGQSPDSETYTDDDRYIPFLQGCGDFTGSYPETGVFCTSPGKVAKEGSLLVSVRAPVGTTNVADKDYCIGRGLAAVKSNIVSALYLREAFTVSASFLHRRAQGSTFDAICAKDLSEMKIPMPKNRRVGEKVTDIIQCLNSELDATQALIDKYTAIKQGMMADLFSRGIDPETKTLRPTFEEAPELYYKTPLGMLPKGWKVIELENLLDEVTSPMRSGPFGSALLKEELVSEGIPLLGIDNIFVERFKASYKRFVTERKFRELSRYAVRERDVVITIMGTVGRSCVIPESIGLALSSKHLWTMTFDKEQILPELVCWQLNHSPWAESWFRRESQGGVMDAIQSQTLKKLKLVVPSPVEQNAIYERYENLNNHIEVNQTSLDKLKLQKTGLMQDLLTGKVPVPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZS9</accession>
    <name>D0YZS9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Tellurite resistance protein-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002792</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301020.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002792"/>
    <dbReference type="EnsemblBacteria" id="EEZ41760">
        <property type="protein sequence ID" value="EEZ41760"/>
        <property type="gene ID" value="VDA_002792"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0500">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1865374at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="191" mass="21446" checksum="A8C58F582AE390DA" modified="2010-01-19" version="1">MSIDFYNTHADDFYQSTVNVDVSPLLERFIPYLSPHAHVLDAGCGSGRDSKSFLDMGYQVTAIDASEELGKRAEQLIGQSVEITTFQNFTSQTQFDGIWACASLLHVPSHELASVFNKLSNMLVTGGAFYCSFKYGNDDVERNGRFFTNSTEQRLQSFLVGSPLQIQETWITGDLRPGREDEKWLNVILVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z022</accession>
    <name>D0Z022_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Aerobic respiration control sensor protein</fullName>
            <ecNumber evidence="11">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">VDA_002885</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 23">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 11">Cell inner membrane</location>
            <topology evidence="2 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="12">Activation requires a sequential transfer of a phosphate group from a His in the primary transmitter domain, to an Asp in the receiver domain and to a His in the secondary transmitter domain.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="11"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301271.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002885"/>
    <dbReference type="EnsemblBacteria" id="EEZ41853">
        <property type="protein sequence ID" value="EEZ41853"/>
        <property type="gene ID" value="VDA_002885"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0784">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2198">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5002">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004721">
        <property type="term" value="F:phosphoprotein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
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    <dbReference type="CDD" id="cd00088">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
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    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027460">
        <property type="entry name" value="ArcB_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040642">
        <property type="entry name" value="HKR_ArcB_TM"/>
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    <dbReference type="InterPro" id="IPR036641">
        <property type="entry name" value="HPT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008207">
        <property type="entry name" value="Sig_transdc_His_kin_Hpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014409">
        <property type="entry name" value="Sig_transdc_His_kin_hyb_ArcB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18415">
        <property type="entry name" value="HKR_ArcB_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01627">
        <property type="entry name" value="Hpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003182">
        <property type="entry name" value="ArcB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47226">
        <property type="entry name" value="SSF47226"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
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    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 11" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4 11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0418">Kinase</keyword>
    <keyword evidence="11 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 12 14" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0804">Transcription</keyword>
    <keyword evidence="11" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="10 11" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="20"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="19">
        <location>
            <begin position="153"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="20">
        <location>
            <begin position="226"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="17">
        <location>
            <begin position="289"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="18">
        <location>
            <begin position="533"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="domain" description="HPt" evidence="21">
        <location>
            <begin position="688"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="77"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphohistidine; by autocatalysis" evidence="12">
        <location>
            <position position="292"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="12 14">
        <location>
            <position position="582"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphohistidine" evidence="12 13">
        <location>
            <position position="727"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00022692"/>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR003182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR003182-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="EEZ41853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="788" mass="89180" checksum="453C336DBED2A542" modified="2010-01-19" version="1">MKQIKVLAQFYVDLLVKLGIVRFSLLLALGLVALAILVQVGVTLVLHGEVRDVDIARSVAFGLLITPWAVYFLSVVVEQLEDSRQRLSKLVTKLEEMRSRDMQLNKQLQENITKLNQEIDERQKAEEARELAMEDLENEVYHREKAQLELAEQSALLRSFLDASPDLIYYRNEKNQFSGCNRAMSELVGKSEKELVGLTPWDVYNPELATKIAKTDQRVFDEDVSLTYEQWLEYPDGRKAVFELRKVPFYSRSGRRLGLMGFGRDITERKRYEEAQEKASRDKTSFISTISHELRTPLNGIVGLSRMLLESELTEDQRNYLRTIHISAITLGNIFNDIIDLDKSDRRRLELLPKPLDLPEFITEIGNISALMAEQKGLRFDLEQLTQLPKMIEVDGTRLRQVLWNLMGNATKFTKQGGVILSVSCEVEADQAHIQFEVEDSGIGIPAGELDNIFAMYYQVQQGDDNLHAVGTGIGLAVSRQLVQLMNGDITVSSEEGEGSTFTVNITVPILACNTVSAEEDEELPSVPQLGLNIFMVEDIELNVTVAKSLLESLGHHVTVAMRGDEALEMFDPEEYDLVLLDIQLPDMTGFEIAQTLRERYQHLPALVALTANVIKDKSEYLEQGMDEALSKPLSVKAITEVIQRLVLTCSLDDEQEEALPFSANSQDQMYEQLLDLEMLSSYVEIVGPKPVLDSIAMFEEMMPGYLEILDSNMMAKDQDGIKFEAHKIKGAAGSIGLKHIQQVAQMAQSPELPTWWENINDWVDEIKYGYQDDLKVLKAWLAQYEKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0B6</accession>
    <name>D0Z0B6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ThrE_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_002979</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301449.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002979"/>
    <dbReference type="EnsemblBacteria" id="EEZ41947">
        <property type="protein sequence ID" value="EEZ41947"/>
        <property type="gene ID" value="VDA_002979"/>
    </dbReference>
    <dbReference type="GeneID" id="57340709"/>
    <dbReference type="eggNOG" id="COG3610">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1567942at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024528">
        <property type="entry name" value="ThrE_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12821">
        <property type="entry name" value="ThrE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="54"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="88"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="130"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="ThrE_2" evidence="6">
        <location>
            <begin position="14"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="158" mass="17259" checksum="9CE385D338FEEA46" modified="2010-01-19" version="1">MNDMLTLLLALANDMFFAMIPAVGFALVFNVPPKALKYCAIGGALGHGCRFLLMHWGVPIEWATLAAATLVGMIGVHWSHRFLAHPKVFTVAAMIPMVPGVFAFKAMIAVVEINHRGFSLELWGLMVENVLKAIFIIAALAIGLAMPGLLFYRRRPVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0C3</accession>
    <name>D0Z0C3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 8 11">Malate dehydrogenase</fullName>
            <ecNumber evidence="5 8 11">1.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">mdh</name>
        <name evidence="15" type="ORF">VDA_002986</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 8">Catalyzes the reversible oxidation of malate to oxaloacetate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8 11">
            <text>(S)-malate + NAD(+) = H(+) + NADH + oxaloacetate</text>
            <dbReference type="Rhea" id="RHEA:21432"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.37"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4 8">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the LDH/MDH superfamily. MDH type 1 family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.37" evidence="5 8 11"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301467.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002986"/>
    <dbReference type="EnsemblBacteria" id="EEZ41954">
        <property type="protein sequence ID" value="EEZ41954"/>
        <property type="gene ID" value="VDA_002986"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0039">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="870724at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030060">
        <property type="term" value="F:L-malate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006108">
        <property type="term" value="P:malate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01337">
        <property type="entry name" value="MDH_glyoxysomal_mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01516">
        <property type="entry name" value="Malate_dehydrog_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001557">
        <property type="entry name" value="L-lactate/malate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022383">
        <property type="entry name" value="Lactate/malate_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001236">
        <property type="entry name" value="Lactate/malate_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015955">
        <property type="entry name" value="Lactate_DH/Glyco_Ohase_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001252">
        <property type="entry name" value="Malate_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010097">
        <property type="entry name" value="Malate_DH_type1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023958">
        <property type="entry name" value="Malate_DH_type1_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02866">
        <property type="entry name" value="Ldh_1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00056">
        <property type="entry name" value="Ldh_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000102">
        <property type="entry name" value="Lac_mal_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56327">
        <property type="entry name" value="SSF56327"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01772">
        <property type="entry name" value="MDH_euk_gproteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00068">
        <property type="entry name" value="MDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0520">NAD</keyword>
    <keyword evidence="8 12 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8 11" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Ldh_1_N" evidence="13">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="Ldh_1_C" evidence="14">
        <location>
            <begin position="147"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8 9">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="7"/>
            <end position="13"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="117"/>
            <end position="119"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="227"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00020382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEZ41954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="312" mass="32284" checksum="428C38A5DB432AB3" modified="2010-01-19" version="1">MKVAVIGAAGGIGQALALLLKNRLPAGSDLALYDIAPVTPGVAADLSHIPTPVSIKGYAGEDPTPALEGADVVLISAGVARKPGMDRSDLFNVNAGIVKSLAEKIAVVCPNACVGIITNPVNTTVAIAAEVLKKAGVYDKRKLFGITTLDVIRSETFVAELKGKAPCDIRVPVIGGHSGVTILPLLSQVEGVEFTEEEVQALTPRIQNAGTEVVEAKAGGGSATLSMGQAACRFGLALVRALQGEHGVVECAYVEGNGEHARFFAQPVLLGKDGIEEVMDYGTLSAFEQQALESMLDTLRGDIAIGEEFAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0C6</accession>
    <name>D0Z0C6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TRAP-type uncharacterized transport system fused permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002989</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301492.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41957">
        <property type="protein sequence ID" value="EEZ41957"/>
        <property type="gene ID" value="VDA_002989"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4666">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="271112at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010656">
        <property type="entry name" value="DctM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021814">
        <property type="entry name" value="DUF3394"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011853">
        <property type="entry name" value="TRAP_DctM-Dct_fused"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06808">
        <property type="entry name" value="DctM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11874">
        <property type="entry name" value="DUF3394"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02123">
        <property type="entry name" value="TRAP_fused"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="194"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="323"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="362"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="389"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="442"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="466"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="516"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="553"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="583"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="644"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="671"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="702"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="domain" description="DctM" evidence="2">
        <location>
            <begin position="136"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="856" mass="93025" checksum="40A96A2E9FA866BE" modified="2010-01-19" version="1">MKTEKNHTAQHVEDLVAQSDTGARTPSGLAGKILLSIALCWSLFQLWYASPLPFIFNVGIFNDTQARAIHLSFAMFLAFTAYPAFKHSARDQIPLLDWLFAFAGSFSACYLFIFYQQLAERSGAPTTPDIYIACTGMILLLEATRRTLGPPLMVVAAIFLTYTFAGPHMPDVIAHKGASLNKAMSHLWLTTEGVYGVALGVSTSFVFLFVLFGAMLEKAGAGAYFIKLAFSLLGHMKGGPAKAAVVASGLSGLVSGSSIANVVTTGTFTIPLMKRVGFPGTKAGAVEVAASTNGQLTPPIMGAAAFLMVEYVGISYVEVIKAAILPAAISYIALLYIVHLEACKANMSGLPRKHQPSMAQKLLSFIFTILLFLVISAAVYYGIGWTKTVFGVLATPMITIALLIAYVLLIKLAACYQDHLLEDPNQELTYVPDPLPTLKSGLYFLLPIVVLVWCLTVERFSPGLSAFWATVFMIFILLTQRPLLALFTQEQTLSQAFAQGGQDLIASLISGARNMIGIGVATAAAGIIVGVVTLTGIGLVMTDFVEFISGGNILLMLIFTAVISLILGMGLPTTANYIVVSTLMAPVIVTLGAQHGLIIPLIAVHLFVFYFGILADDTPPVGLAAFAAAAIAKSDPIKTGIQGFTYDIRTAILPFMFIFNTQLLLLNIDSWWHLLLTVISAILAMLTFSVATQGWWLTKTKWWEVIALLVITFSLFRPGFWWDQIYPAKNILPGKNIEQVVANLPIGSPIELQVTGINLEGKEVSKHVLLPFDDKAETAQQRIQSTGLNLRQEENTIWVDMVDFASPAEAVGIDFDWQIQSISVPNPRPMKEWVFIPVLFILSLLAWNHRRRALTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0C8</accession>
    <name>D0Z0C8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">UDP-N-acetylmuramate--L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptandioate ligase</fullName>
            <ecNumber evidence="6">6.3.2.45</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Murein peptide ligase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">mpl</name>
        <name evidence="10" type="ORF">VDA_002991</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>ATP + L-alanyl-gamma-D-glutamyl-meso-diaminoheptanedioate + UDP-N-acetyl-alpha-D-muramate = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate</text>
            <dbReference type="Rhea" id="RHEA:29563"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61401"/>
            <dbReference type="ChEBI" id="CHEBI:70757"/>
            <dbReference type="ChEBI" id="CHEBI:83905"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.45"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6">Cell wall biogenesis; peptidoglycan recycling.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the MurCDEF family. Mpl subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.45" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301496.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002991"/>
    <dbReference type="EnsemblBacteria" id="EEZ41959">
        <property type="protein sequence ID" value="EEZ41959"/>
        <property type="gene ID" value="VDA_002991"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0773">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="307881at2"/>
    <dbReference type="UniPathway" id="UPA00544"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106418">
        <property type="term" value="F:UDP-N-acetylmuramate-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009254">
        <property type="term" value="P:peptidoglycan turnover"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02020">
        <property type="entry name" value="Mpl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005757">
        <property type="entry name" value="Mpl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000713">
        <property type="entry name" value="Mur_ligase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01225">
        <property type="entry name" value="Mur_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01081">
        <property type="entry name" value="mpl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1 6" id="KW-0132">Cell division</keyword>
    <keyword evidence="2 6" id="KW-0133">Cell shape</keyword>
    <keyword evidence="5 6" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 6" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase" evidence="7">
        <location>
            <begin position="2"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_M" evidence="9">
        <location>
            <begin position="108"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="8">
        <location>
            <begin position="311"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="110"/>
            <end position="116"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ41959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="451" mass="49072" checksum="BF574712D591C160" modified="2010-01-19" version="1">MHIHILGICGTFMGGAAILARQLGHKVTGCDANVYPPMSTLLESQGIEIIQGYDPSQLDPAPDLVVIGNAMSRGNPCVEYVLNHNLRYTSGPQWLQEFLLHDRWVMAVSGTHGKTTTASMLAWILEDCGYNPGFLVGGVLGNFGVSARLGESMFFVVEADEYDSAFFDKRSKFVHYHPRTLIMNNLEFDHADIFDDLKSIQRQFHHLVRTVPGNGRILAPHGVAAIDETLEMGCWSELEYIGGDGHWQAEKLMADGSQFSVLLDGEKVGVVNWPLVGDHNVNNALMAIAAARHVGVTPDLACEALGNFINTKRRLELKGEVNGVKVYDDFAHHPTAIELTLGGLRAKVGADARILAVLEPRSNTMKLGVHKDDLAPSLQAADEVFLFQPNNIPWSVSDIANQCSQPAFTNDDLDGLVAEICAHAKEGDTILVMSNGGFGGIHDKLLAKLGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0E7</accession>
    <name>D0Z0E7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Sulfite reductase [NADPH] hemoprotein beta-component</fullName>
            <shortName evidence="9">SiR-HP</shortName>
            <shortName evidence="9">SiRHP</shortName>
            <ecNumber evidence="9">1.8.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">cysI</name>
        <name evidence="12" type="ORF">VDA_003011</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>3 H2O + hydrogen sulfide + 3 NADP(+) = 4 H(+) + 3 NADPH + sulfite</text>
            <dbReference type="Rhea" id="RHEA:13801"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17359"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.8.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="9">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>siroheme</name>
            <dbReference type="ChEBI" id="CHEBI:60052"/>
        </cofactor>
        <text evidence="9">Binds 1 siroheme per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="9">Sulfur metabolism; hydrogen sulfide biosynthesis; hydrogen sulfide from sulfite (NADPH route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.2" evidence="9"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301559.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003011"/>
    <dbReference type="EnsemblBacteria" id="EEZ41978">
        <property type="protein sequence ID" value="EEZ41978"/>
        <property type="gene ID" value="VDA_003011"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0155">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1588103at2"/>
    <dbReference type="UniPathway" id="UPA00140">
        <property type="reaction ID" value="UER00207"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009337">
        <property type="term" value="C:sulfite reductase complex (NADPH)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004783">
        <property type="term" value="F:sulfite reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019344">
        <property type="term" value="P:cysteine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070814">
        <property type="term" value="P:hydrogen sulfide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000103">
        <property type="term" value="P:sulfate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.413.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01540">
        <property type="entry name" value="CysI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011786">
        <property type="entry name" value="CysI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005117">
        <property type="entry name" value="NiRdtase/SiRdtase_haem-b_fer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036136">
        <property type="entry name" value="Nit/Sulf_reduc_fer-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006067">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045169">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045854">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006066">
        <property type="entry name" value="NO2/SO3_Rdtase_FeS/sirohaem_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11493">
        <property type="entry name" value="PTHR11493"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01077">
        <property type="entry name" value="NIR_SIR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03460">
        <property type="entry name" value="NIR_SIR_ferr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00397">
        <property type="entry name" value="SIROHAEM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55124">
        <property type="entry name" value="SSF55124"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56014">
        <property type="entry name" value="SSF56014"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02041">
        <property type="entry name" value="CysI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00365">
        <property type="entry name" value="NIR_SIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 9" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="2 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8 9" id="KW-0198">Cysteine biosynthesis</keyword>
    <keyword evidence="3 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 9" id="KW-0408">Iron</keyword>
    <keyword evidence="7 9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9" id="KW-0521">NADP</keyword>
    <keyword evidence="5 9 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NIR_SIR_ferr" evidence="11">
        <location>
            <begin position="70"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="NIR_SIR" evidence="10">
        <location>
            <begin position="164"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="NIR_SIR_ferr" evidence="11">
        <location>
            <begin position="344"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="domain" description="NIR_SIR" evidence="10">
        <location>
            <begin position="422"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="426"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="432"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="472"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="476"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="476"/>
        </location>
        <ligand>
            <name>siroheme</name>
            <dbReference type="ChEBI" id="CHEBI:60052"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ41978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="563" mass="63130" checksum="ACA2F45C955FA843" modified="2010-01-19" version="1">MSEQKLSDNERLKRESNHLRGTIEQDLNDAITGGFTSDNFQLIRFHGMYQQDDRDIRSERAKQKLEPLHNVMLRARMPGGVITPKQWLAIDKFATEHSLYGSIRLTTRQTFQFHGVLKPNIKLMHQTLNQIGIDSIATAGDVNRNVLCTSNPIESKLHQQAYEWAAKISEHLLPKTRAYAEIWLDGEKLETTDKEPILGSTYLPRKFKTTVVIPPQNDVDVHANDLNFVAIAQEGELVGFNVLVGGGLAMTHGDKSTYPRRADDFGFIALEHTLAIAEAVVTTQRDWGNRSHRKNAKTKYTLDRVGVDVFKAEVEKRAGVSFAPSRPYEFTERGDRIGWVQGIDGYEHLTLFIENGRLLDFPDKPLKTGVAEIAKIHQGDFRMTANQNLIVAKVPLSEKARIEKIARDHGLINDGVSEQRKNSMACVSLPTCPLAMAEAERFLPSFVTDVEQILQRHGLPTDDNIILRVTGCPNGCGRAMLAEIGLVGKAPGRYNLHLGGNRSGTRVPKMYRENITVAEILTEIDQLVSRWAKEREAQEGFGDFTIRAGIIAPVEVSKRDFYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0G0</accession>
    <name>D0Z0G0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">30S ribosomal protein S18</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rpsR</name>
        <name evidence="8" type="ORF">VDA_003024</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6 7">Belongs to the bacterial ribosomal protein bS18 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_002539422.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003024"/>
    <dbReference type="EnsemblBacteria" id="EEZ41991">
        <property type="protein sequence ID" value="EEZ41991"/>
        <property type="gene ID" value="VDA_003024"/>
    </dbReference>
    <dbReference type="GeneID" id="61231651"/>
    <dbReference type="eggNOG" id="COG0238">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1940575at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00270">
        <property type="entry name" value="Ribosomal_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001648">
        <property type="entry name" value="Ribosomal_S18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018275">
        <property type="entry name" value="Ribosomal_S18_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036870">
        <property type="entry name" value="Ribosomal_S18_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13479">
        <property type="entry name" value="PTHR13479"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01084">
        <property type="entry name" value="Ribosomal_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00974">
        <property type="entry name" value="RIBOSOMALS18"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46911">
        <property type="entry name" value="SSF46911"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00165">
        <property type="entry name" value="S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00057">
        <property type="entry name" value="RIBOSOMAL_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ41991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="75" mass="8912" checksum="F657266E92DDA9B3" modified="2010-01-19" version="1">MARFFRRRKFCRFTAEGVQEIDYKDVATLKNYITEAGKIVPSRITGTRAKYQRQLARAIKRSRYLALLPYTDKHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-12-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0R6</accession>
    <name>D0Z0R6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">UPF0761 membrane protein VDA_003130</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_003130</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the UPF0761 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003130"/>
    <dbReference type="EnsemblBacteria" id="EEZ42097">
        <property type="protein sequence ID" value="EEZ42097"/>
        <property type="gene ID" value="VDA_003130"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1295">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00672">
        <property type="entry name" value="UPF0761"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023679">
        <property type="entry name" value="UPF0761_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017039">
        <property type="entry name" value="Virul_fac_BrkB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30213">
        <property type="entry name" value="PTHR30213"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03631">
        <property type="entry name" value="Virul_fac_BrkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF035875">
        <property type="entry name" value="RNase_BN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00765">
        <property type="entry name" value="yihY_not_rbn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="55"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="122"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="159"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="203"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="228"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="265"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ42097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="322" mass="35806" checksum="B1675083395379EF" modified="2010-01-19" version="1">MIMPSFDKQLRKSFPFMADNKSSNKLHFTTRISMTFAYFRYLFQRINHDRLTVTAGSMAYVTLLSLVPLITVVLSALSSFPVFQGLGEVLQNFVIENFVPAAGEVVKTYLNQFVANAGKMTAVGIGALFVVAMMLISSIDTALNYIWRVSEKRRPVISFSIYWMVLTLGPILVGSSLAVSSYLGSLNIMGSDAVNGLLQQSLRWLPVMMSTMAFLGLYLLVPNTKVRFHHAVIGAGCASLLFELSKKGFALYITNFPSYQVIYGALAVIPILFVWVYLCWCIVLLGAEITASLGERKHWDFTQVEAQSEPDSIIETTTKDKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0Y9</accession>
    <name>D0Z0Y9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 8">Methionyl-tRNA formyltransferase</fullName>
            <ecNumber evidence="4 8">2.1.2.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">fmt</name>
        <name evidence="11" type="ORF">VDA_003203</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 8">Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>(6S)-10-formyltetrahydrofolate + L-methionyl-tRNA(fMet) = (6S)-5,6,7,8-tetrahydrofolate + H(+) + N-formyl-L-methionyl-tRNA(fMet)</text>
            <dbReference type="Rhea" id="RHEA:24380"/>
            <dbReference type="Rhea" id="RHEA-COMP:9952"/>
            <dbReference type="Rhea" id="RHEA-COMP:9953"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
            <dbReference type="ChEBI" id="CHEBI:78530"/>
            <dbReference type="ChEBI" id="CHEBI:78844"/>
            <dbReference type="EC" id="2.1.2.9"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the Fmt family.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.9" evidence="4 8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302152.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003203"/>
    <dbReference type="EnsemblBacteria" id="EEZ42170">
        <property type="protein sequence ID" value="EEZ42170"/>
        <property type="gene ID" value="VDA_003203"/>
    </dbReference>
    <dbReference type="GeneID" id="57340387"/>
    <dbReference type="eggNOG" id="COG0223">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2009156at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004479">
        <property type="term" value="F:methionyl-tRNA formyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd08646">
        <property type="entry name" value="FMT_core_Met-tRNA-FMT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08704">
        <property type="entry name" value="Met_tRNA_FMT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.25.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00182">
        <property type="entry name" value="Formyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005794">
        <property type="entry name" value="Fmt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005793">
        <property type="entry name" value="Formyl_trans_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037022">
        <property type="entry name" value="Formyl_trans_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002376">
        <property type="entry name" value="Formyl_transf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036477">
        <property type="entry name" value="Formyl_transf_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011034">
        <property type="entry name" value="Formyl_transferase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001555">
        <property type="entry name" value="GART_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044135">
        <property type="entry name" value="Met-tRNA-FMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041711">
        <property type="entry name" value="Met-tRNA-FMT_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02911">
        <property type="entry name" value="Formyl_trans_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00551">
        <property type="entry name" value="Formyl_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50486">
        <property type="entry name" value="SSF50486"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53328">
        <property type="entry name" value="SSF53328"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00460">
        <property type="entry name" value="fmt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00373">
        <property type="entry name" value="GART"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Formyl_trans_N" evidence="9">
        <location>
            <begin position="6"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="Formyl_trans_C" evidence="10">
        <location>
            <begin position="207"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Tetrahydrofolate (THF) binding" evidence="8">
        <location>
            <begin position="113"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ42170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="314" mass="34317" checksum="DE429ACA36B82453" modified="2010-01-19" version="1">MSKPLRIVFAGTPDFAARHLAALLSSEHEVIAVYTQPDRPAGRGKKLTASPVKHIALEHDIPVYQPASLRNEEAQQELAALNADLMVVVAYGLLLPKEVLDTPKLGCINVHGSILPRWRGAAPIQRSIWAGDSETGVTIMQMDEGLDTGDMLQIATLPIEANDTSATMYEKLAELGPVALVDCLADIATGKAVATKQDDEQANYAKKLSKEEAKIDWTMDAVAIERCVRAFNPWPMSYFEVSEQNIKVWRSEVVAEDHGKQPGTILSADKHGIVVATGHGALRLLELQPPGKKAMQVQDLLNSRREWFEVGSVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z108</accession>
    <name>D0Z108_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="11 19">Branched-chain-amino-acid aminotransferase</fullName>
            <shortName evidence="19">BCAT</shortName>
            <ecNumber evidence="10 19">2.6.1.42</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">ilvE</name>
        <name evidence="20" type="ORF">VDA_003222</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 19">Acts on leucine, isoleucine and valine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 19">
            <text>2-oxoglutarate + L-isoleucine = (S)-3-methyl-2-oxopentanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24801"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:35146"/>
            <dbReference type="ChEBI" id="CHEBI:58045"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 19">
            <text>2-oxoglutarate + L-leucine = 4-methyl-2-oxopentanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:18321"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:17865"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57427"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 19">
            <text>2-oxoglutarate + L-valine = 3-methyl-2-oxobutanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24813"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57762"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4 18">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6 19">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 4/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8 19">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 4/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7 19">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 4/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9 17">Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.42" evidence="10 19"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302203.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003222"/>
    <dbReference type="EnsemblBacteria" id="EEZ42189">
        <property type="protein sequence ID" value="EEZ42189"/>
        <property type="gene ID" value="VDA_003222"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0115">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1275805at2"/>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00058"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00073"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00062"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052656">
        <property type="term" value="F:L-isoleucine transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052654">
        <property type="term" value="F:L-leucine transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050048">
        <property type="term" value="F:L-leucine:2-oxoglutarate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052655">
        <property type="term" value="F:L-valine transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01557">
        <property type="entry name" value="BCAT_beta_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018300">
        <property type="entry name" value="Aminotrans_IV_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005785">
        <property type="entry name" value="B_amino_transI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043131">
        <property type="entry name" value="BCAT-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033939">
        <property type="entry name" value="BCAT_family"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="SSF56752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01122">
        <property type="entry name" value="ilvE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00770">
        <property type="entry name" value="AA_TRANSFER_CLASS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13 19" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="12 19 20" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="16 19" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="15 18" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14 19 20" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00003109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00004824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00004931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00005072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00009320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00013053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00018179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU004106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU004516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="RuleBase" id="RU364094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="EEZ42189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="309" mass="33979" checksum="451B6289DAEEBD5E" modified="2010-01-19" version="1">MANTADYIWFNGEMVAWADANVHVLTHAMHYGTSVFEGIRCYNTPQGPAVFRHREHMERLKNSAKIYRFPINYSVDELMEHCRATLRTNKLESAYIRPLAYVGNVGLGVCPPPNTEMELIIAAFPWGAYLGDEALENGVDAMISSWHRAAPNTIPTAAKAGGNYLSSLLVGGEARRHGYAEGIALNVEGYISEGAGENLFVVRNGIISTPPATGSILPGITRDTIMTLAKELGYEVREENIAREALYLADEVFMTGTAAEIVPVRSIDQITVGVGKRGPVTKVMQEAFFGLFNGTTEDKWGWLDYVNEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z140</accession>
    <name>D0Z140_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative OmpA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_003254</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302299.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003254"/>
    <dbReference type="EnsemblBacteria" id="EEZ42221">
        <property type="protein sequence ID" value="EEZ42221"/>
        <property type="gene ID" value="VDA_003254"/>
    </dbReference>
    <dbReference type="GeneID" id="57340335"/>
    <dbReference type="eggNOG" id="COG2885">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2018797at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07185">
        <property type="entry name" value="OmpA_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039567">
        <property type="entry name" value="Gly-zipper"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006664">
        <property type="entry name" value="OMP_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006665">
        <property type="entry name" value="OmpA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036737">
        <property type="entry name" value="OmpA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13488">
        <property type="entry name" value="Gly-zipper_Omp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00691">
        <property type="entry name" value="OmpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01021">
        <property type="entry name" value="OMPADOMAIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103088">
        <property type="entry name" value="SSF103088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51123">
        <property type="entry name" value="OMPA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="OmpA-like" evidence="4">
        <location>
            <begin position="112"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ42221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="229" mass="23539" checksum="5BBD3E300DEAA1F4" modified="2010-01-19" version="1">MANNVSNASNKWVRAAVISVIAAMTMTGCSTVNPYTGESQTADATSGSIIGALAGAAIGVASSSKHDRGKGALIGAASGAALGGGIGYYMDVQAAKLRKQLASSGITVTRNGNNIVLNMPNEITFGVDQTTLNQRAMNALHNVALVAKEYNKTQLNVYGFTDSTGAASYNQRLSQVRAAEVGNYLIRQGVAANRVVSQGMGEASPIATNSTAAGRAENRRVQIVMSPLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z141</accession>
    <name>D0Z141_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">GDT1 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_003255</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the GDT1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302304.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ42222">
        <property type="protein sequence ID" value="EEZ42222"/>
        <property type="gene ID" value="VDA_003255"/>
    </dbReference>
    <dbReference type="GeneID" id="57340334"/>
    <dbReference type="eggNOG" id="COG2119">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2050363at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001727">
        <property type="entry name" value="Gdt1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12608">
        <property type="entry name" value="PTHR12608"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01169">
        <property type="entry name" value="UPF0016"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="38"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="67"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="131"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="165"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ42222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="185" mass="19774" checksum="355D4F2ECE429866" modified="2010-01-19" version="1">MSVLAISITTVALAEIGDKTQLLSLMLASRYRKPIPIILAIFAATVANHALAAWLGVVVADYLTPQILKWVLVISFIAMALWILVPDKLDDEETLSNRGPFIASFIAFFVAEIGDKTQVATTMLGAKYHDALMWVVLGTTIGMLLANVPVVLIGKLSADKMPLGLIRKVTAALFVVLAVAAALGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z168</accession>
    <name>D0Z168_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Probable protein kinase UbiB</fullName>
            <ecNumber evidence="9">2.7.-.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Ubiquinone biosynthesis protein UbiB</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ubiB</name>
        <name evidence="11" type="ORF">VDA_003282</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 9">Cofactor biosynthesis; ubiquinone biosynthesis [regulation].</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the ABC1 family. UbiB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.-.-" evidence="9"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003282"/>
    <dbReference type="EnsemblBacteria" id="EEZ42249">
        <property type="protein sequence ID" value="EEZ42249"/>
        <property type="gene ID" value="VDA_003282"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0661">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010795">
        <property type="term" value="P:regulation of ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd13972">
        <property type="entry name" value="UbiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00414">
        <property type="entry name" value="UbiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010232">
        <property type="entry name" value="UbiB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045308">
        <property type="entry name" value="UbiB_bact"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01982">
        <property type="entry name" value="UbiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="2 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="11" id="KW-0830">Ubiquinone</keyword>
    <keyword evidence="5 9" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="499"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="523"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="domain" description="ABC1" evidence="10">
        <location>
            <begin position="94"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="9">
        <location>
            <position position="288"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="130"/>
            <end position="138"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ42249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="545" mass="63188" checksum="1A7DBB310F2DB160" modified="2010-01-19" version="1">MMTFSELRRLYHITAVQLRYGLDELLPDDPRVQLPKKLRKSLFWLKNEHQDKPLGQRLRLALQELGPVWIKFGQMLSTRRDLFPPHIADQLALLQDQVEPFDGELAKAQMEQALGGALEQWFDDFSIEPLASASIAQVHTAVLKENGREVVLKVIRPDILPVIQADIKLMYRMARLLAKLVPEARRLRPVEVVREYEKTLIDELDLMREAANSIQLRRNFAGDETLYVPEVFSDYCRTNLLVMERIYGIQVSNIEALKANGTNLKLLSENAVNIFFTQVFRDSFFHADMHPGNIFVSYEHPETPQWIALDCGIVGTLNREDKRYLAENLLAFFHRDYRKVAELHVDSGWVPHDTNIDEFEFAIRTVCEPIFEKPLCEISFGHVLLNLFNTARRFNMEVQPQLVLLQKTLLYVEGLGRQLYPQLDLWATAKPFLEDWMSRQVGTQAIMDAVKNKAPFWAEKLPELPELLYDSLRQGKAMNQRVDKLYEHFMTNRRYQNQARFYFGIGATLIICSAILFSNHVATYPAISAGVGVTFWFLGWRNCRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z199</accession>
    <name>D0Z199_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">4-hydroxybenzoate octaprenyltransferase</fullName>
            <ecNumber evidence="9">2.5.1.39</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">4-HB polyprenyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ubiA</name>
        <name evidence="10" type="ORF">VDA_003313</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>4-hydroxybenzoate + all-trans-octaprenyl diphosphate = 4-hydroxy-3-all-trans-octaprenylbenzoate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:27782"/>
            <dbReference type="ChEBI" id="CHEBI:1617"/>
            <dbReference type="ChEBI" id="CHEBI:17879"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57711"/>
            <dbReference type="EC" id="2.5.1.39"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="9">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell inner membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the UbiA prenyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.39" evidence="9"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302470.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003313"/>
    <dbReference type="EnsemblBacteria" id="EEZ42280">
        <property type="protein sequence ID" value="EEZ42280"/>
        <property type="gene ID" value="VDA_003313"/>
    </dbReference>
    <dbReference type="GeneID" id="57340246"/>
    <dbReference type="eggNOG" id="COG0382">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1472516at2"/>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002083">
        <property type="term" value="F:4-hydroxybenzoate decaprenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047293">
        <property type="term" value="F:4-hydroxybenzoate nonaprenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008412">
        <property type="term" value="F:4-hydroxybenzoate octaprenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd13959">
        <property type="entry name" value="PT_UbiA_COQ2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01635">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006370">
        <property type="entry name" value="HB_polyprenyltransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039653">
        <property type="entry name" value="Prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030470">
        <property type="entry name" value="UbiA_prenylTrfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11048">
        <property type="entry name" value="PTHR11048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01474">
        <property type="entry name" value="ubiA_proteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00943">
        <property type="entry name" value="UBIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="2 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5 9" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="164"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="207"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="235"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="266"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ42280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="287" mass="32019" checksum="D4E0352F648ED5CA" modified="2010-01-19" version="1">MLEVTKARAYWQLARFDRPIGSLLLLWPTLWALFLAADGWPSPHVLVVFVLGVIFMRAAGCVINDFADRNFDGHVKRTCQRPMPSGKVSEREALGLFGLLVLISFLLVLTMNTLTISLSVIGLALAAAYPFMKRYTHLPQLVLGVAFGWSIPMAYAAQSGQLPLAAWLLFAANILWTIAYDTQYAMVDRDDDLKIGIKSTAILFGRFDKMIIGMLQLGTLLLLTAVGGVLGLSQIFYWFLLLAAMLFVYQQMLIKQRQREDCFRAFLNNNYVGMVICIGLAVSVLLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1C2</accession>
    <name>D0Z1C2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">DNA-directed RNA polymerase subunit omega</fullName>
            <shortName evidence="11">RNAP omega subunit</shortName>
            <ecNumber evidence="2 11">2.7.7.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 11">RNA polymerase omega subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9 11">Transcriptase subunit omega</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">rpoZ</name>
        <name evidence="12" type="ORF">VDA_003336</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 11">
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="11">The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the RNA polymerase subunit omega family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="2 11"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302516.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003336"/>
    <dbReference type="EnsemblBacteria" id="EEZ42303">
        <property type="protein sequence ID" value="EEZ42303"/>
        <property type="gene ID" value="VDA_003336"/>
    </dbReference>
    <dbReference type="GeneID" id="57340219"/>
    <dbReference type="eggNOG" id="COG1758">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1864134at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.940.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00366">
        <property type="entry name" value="RNApol_bact_RpoZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003716">
        <property type="entry name" value="DNA-dir_RNA_pol_omega"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006110">
        <property type="entry name" value="Pol_omega/Rpo6/RPB6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036161">
        <property type="entry name" value="RPB6/omega-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34476">
        <property type="entry name" value="PTHR34476"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01192">
        <property type="entry name" value="RNA_pol_Rpb6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01409">
        <property type="entry name" value="RNA_pol_Rpb6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63562">
        <property type="entry name" value="SSF63562"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00690">
        <property type="entry name" value="rpoZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11 12" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="6 11 12" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 11 12" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ42303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="91" mass="10103" checksum="1C3408DE31E5F395" modified="2010-01-19" version="1">MARVTVQDAVDKIGNRFDLIQIAARRARQMQTGAKDPLVPEENDKYTVIALREIEEGLITKDILDARERQELQEQEAAELAAVSAIAGGNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1D1</accession>
    <name>D0Z1D1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">50S ribosomal protein L28</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpmB</name>
        <name evidence="7" type="ORF">VDA_003345</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the bacterial ribosomal protein bL28 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302534.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003345"/>
    <dbReference type="EnsemblBacteria" id="EEZ42312">
        <property type="protein sequence ID" value="EEZ42312"/>
        <property type="gene ID" value="VDA_003345"/>
    </dbReference>
    <dbReference type="GeneID" id="57340210"/>
    <dbReference type="eggNOG" id="COG0227">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2062238at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.170.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00373">
        <property type="entry name" value="Ribosomal_L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034704">
        <property type="entry name" value="L28p-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026569">
        <property type="entry name" value="Ribo_L28/L24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037147">
        <property type="entry name" value="Ribo_L28/L24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001383">
        <property type="entry name" value="Ribosomal_L28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13528">
        <property type="entry name" value="PTHR13528"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00830">
        <property type="entry name" value="Ribosomal_L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143800">
        <property type="entry name" value="SSF143800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00009">
        <property type="entry name" value="L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ42312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="78" mass="9034" checksum="4E5856B216B13C61" modified="2010-01-19" version="1">MSRVCQVTGKRPVTGNNRSHARNATKRRFLPNLQTHRFWVESEKRFVKLRLSAKGMRIIDKKGIDAVLVDMRARGENV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1I6</accession>
    <name>D0Z1I6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Dihydrolipoamide dehydrogenase</fullName>
            <ecNumber evidence="8">1.8.1.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_003400</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="4">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.4" evidence="8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302646.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003400"/>
    <dbReference type="EnsemblBacteria" id="EEZ42367">
        <property type="protein sequence ID" value="EEZ42367"/>
        <property type="gene ID" value="VDA_003400"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1249">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="267896at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004148">
        <property type="term" value="F:dihydrolipoyl dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036324">
        <property type="entry name" value="Mn/Fe_SOD_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="SSF55424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="7">
        <location>
            <begin position="7"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_dim" evidence="6">
        <location>
            <begin position="350"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="448"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="142"/>
            <end position="144"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="179"/>
            <end position="186"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="269"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="311"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="5">
        <location>
            <begin position="43"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ42367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="483" mass="52578" checksum="DA7EDDE85A5275FB" modified="2010-01-19" version="1">MKTLNVDVAVIGGGTAGLGSYRAAKAYTDSVVMIEGGPYGTTCARVGCMPSKLLIAAAESVHQIEKAPGFGVHPQGEIVINGREVMDRVKRERDRFVGFVLEGVDEIPAEDKISGYAKFIDNNTLMVDDHTKIIAKRIVIATGSRPAYPAVWNELGDRLVINDDVFEWDDLPNSVAVFGPGVIGLELGQSLKRLGVEVVMFGLGGQVGPLTDPEVMAYANKTFNEEFYLDPDVKVESMVRNGDAVEIKYLGKDGQLKEITVDYVLAATGRRPNVDKLAIENTSLELDDRGVPKADYYTMQTSVDTIFIAGDASNQIPLLHEAADQARIAGDNAGRFPDIRAGLRRSKLSAVFSDPQIAMVGETYKEITIRLGTCGCFATGDVSFENQGRSRVMLRNKGMLHVYGEQGTGRFLGAEMIGPDAEHLAHLLAWAHQNQMTISQMLDMPFYHPVIEEGLRTALRDLNAKLNLGPEMIKHCLDCGPGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1M5</accession>
    <name>D0Z1M5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6 8">50S ribosomal protein L3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rplC</name>
        <name evidence="9" type="ORF">VDA_003439</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 8">One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6 8">Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.</text>
    </comment>
    <comment type="PTM">
        <text evidence="6">Methylated by PrmB.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the universal ribosomal protein uL3 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302783.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003439"/>
    <dbReference type="EnsemblBacteria" id="EEZ42406">
        <property type="protein sequence ID" value="EEZ42406"/>
        <property type="gene ID" value="VDA_003439"/>
    </dbReference>
    <dbReference type="GeneID" id="57340104"/>
    <dbReference type="eggNOG" id="COG0087">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1270636at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01325_B">
        <property type="entry name" value="Ribosomal_L3_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000597">
        <property type="entry name" value="Ribosomal_L3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019927">
        <property type="entry name" value="Ribosomal_L3_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019926">
        <property type="entry name" value="Ribosomal_L3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11229">
        <property type="entry name" value="PTHR11229"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00297">
        <property type="entry name" value="Ribosomal_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03625">
        <property type="entry name" value="L3_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00474">
        <property type="entry name" value="RIBOSOMAL_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0488">Methylation</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="6 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 8" id="KW-0699">rRNA-binding</keyword>
    <feature type="modified residue" description="N5-methylglutamine" evidence="6">
        <location>
            <position position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ42406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="209" mass="22413" checksum="F343429E6CA5157F" modified="2010-01-19" version="1">MIGLIGRKVGMTRIFTEAGVSIPVTVVEVEANRVSQVKTVETDGYNAIQITTGSKKANRVTKPEAGHFAKAGVEAGRGLWEFRLENNEEFAVGAELTVELFNEVKKVDVTGTSKGKGFQGAVKRWNFRTQDMTHGNSLSHRAPGSIGQCQTPGRVFKGKKMAGHMGAERVTTQNLEIVRVDAERNLLLIKGAVPGATGGNVIVKPAVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1R0</accession>
    <name>D0Z1R0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_003474</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303549.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003474"/>
    <dbReference type="EnsemblBacteria" id="EEZ42441">
        <property type="protein sequence ID" value="EEZ42441"/>
        <property type="gene ID" value="VDA_003474"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="630753at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ42441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="368" mass="42411" checksum="BB63B8DB0688E973" modified="2010-01-19" version="1">MEFLVFGEDWQRHPSSTQHLFALFNQQHLVYWINSIGLRQPSISSQDIIRVVEKIKAFKSLQVTKHKQLAQPTKTINPLVWPLPQNKLIKKINQQLLKYQLPIKQEFRVIWCSLPSAVDYLDTCDGDIVVYYCGDDFLALAGVDHRKVEILEQQLVHRADVIFAASPPLQQKFPPEKTHLLPHGVDLDLFTPPALPTNKDQIKTVGFYGSLNTWLDYDLIIRLAQQCPEITFHFVGKKECPASHTLIQQNIQLHPPCSHPELISHLTHWDCAIMPFINNRQIQHCNPLKLREYLASARHIICSDFPAAQQYSSHLTIANNTQQWLNALKNPIPITEQKITMRRQILSTESWQARQQQVIAELQSLISP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-06-02" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1W6</accession>
    <name>D0Z1W6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003530</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ42497">
        <property type="protein sequence ID" value="EEZ42497"/>
        <property type="gene ID" value="VDA_003530"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3105">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="69" mass="7410" checksum="E2285DF6F49E19B9" modified="2010-01-19" version="1">MPNLPAQDNPFAHRISNLTAVKAEHSDDKTQDQPRDYANGATGLFSGKTEDKSEVASEPEKAPEAKVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z232</accession>
    <name>D0Z232_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycosaminoglycan attachment site</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001881</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298868.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001881"/>
    <dbReference type="EnsemblBacteria" id="EEZ40849">
        <property type="protein sequence ID" value="EEZ40849"/>
        <property type="gene ID" value="VDA_001881"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502Z8GP">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1143092at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="339" mass="38620" checksum="E256F3D17070E6B0" modified="2010-01-19" version="1">MLDLFTPIAKDEKQHPLFKMMLQEQFKPERDVLTSWAQGFKDRDGKFTYEFQTTFESSMWELYLYAFLKDLGAQTDFSHHAPDFVTKLDRHITLEATIAAPPQGEEAPVGHTQLFAQMDFAEFNQQSAIRISNSLSSKIKKFRTSYSDLPHVKNKPYVIGLASFDRPFSHFAVNRGIIAVLYGLYVDEETTIAMGANELIKYPVEAVVKNENASIPVGLFTSDEYKDVSAVIYSSLATWGKIRALADNPDAMSVYHTFHLPKGDSIMPEIRNTIKAEYKEEIADGLHILHNPFAEYPLDVNTFNHARVAQYFFDPEKGINVIAPDDFLLLRQLNSFVTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z271</accession>
    <name>D0Z271_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001917</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298932.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001917"/>
    <dbReference type="EnsemblBacteria" id="EEZ40885">
        <property type="protein sequence ID" value="EEZ40885"/>
        <property type="gene ID" value="VDA_001917"/>
    </dbReference>
    <dbReference type="GeneID" id="57341955"/>
    <dbReference type="eggNOG" id="COG1737">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1540164at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901135">
        <property type="term" value="P:carbohydrate derivative metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05013">
        <property type="entry name" value="SIS_RpiR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000281">
        <property type="entry name" value="HTH_RpiR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035472">
        <property type="entry name" value="RpiR-like_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01418">
        <property type="entry name" value="HTH_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01380">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51071">
        <property type="entry name" value="HTH_RPIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH rpiR-type" evidence="1">
        <location>
            <begin position="3"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="2">
        <location>
            <begin position="128"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="285" mass="32502" checksum="E86D57EC28302FC1" modified="2010-01-19" version="1">MNKQDFIDAINHFQSMTDAEQRISQYFMANYSVLPFAKIDELCKQIGVGKATLGRFLQRLGFVGFIDFKKQVTAELTHTLTTPIERYETDNGDLGSSENNLLAQHHTEVLSNLDKTFHNITDEQFESALELMRQPKGKLYVMGSASSEALATYFYLLARYLRREVILIEADISKLPHQLVDVGKDDILFAISYHRYSSVTVRLVKWFHQHGGSIIIMTDQAVNPFAAYSDIQFVVESAGNGFFNNRTAGFAVIEGLIKGLSIHKEKENRFQRIEGLFEEFSFFKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2B3</accession>
    <name>D0Z2B3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000564</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000564"/>
    <dbReference type="EnsemblBacteria" id="EEZ39544">
        <property type="protein sequence ID" value="EEZ39544"/>
        <property type="gene ID" value="VDA_000564"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3153">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="82" mass="8949" checksum="A9F5D1BCEC7A4FFE" modified="2010-01-19" version="1">MIPSQQGKGIGHALIQQGILQAQELGFKGVVLLGEPEYYTRFGFTPSPKLTLDGVPPEFFLVKALEGEIPSGEVSYHPAFFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2B6</accession>
    <name>D0Z2B6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chlorohydrolase/deaminase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000567</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304731.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000567"/>
    <dbReference type="EnsemblBacteria" id="EEZ39547">
        <property type="protein sequence ID" value="EEZ39547"/>
        <property type="gene ID" value="VDA_000567"/>
    </dbReference>
    <dbReference type="GeneID" id="57342953"/>
    <dbReference type="eggNOG" id="COG0402">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1592010at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019338" evidence="1">
        <location>
            <begin position="21"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="domain" description="Amidohydro-rel" evidence="2">
        <location>
            <begin position="79"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="465" mass="50937" checksum="CC63457B2CBE2EBA" modified="2010-01-19" version="1">MFKKTLLAVSLAATSSYAFAVENVDLLIKNAQVLTMDKDKTVFDHGLVAIKGNKIVAVTDGSDIKEYQSAKTIDADGDIVMPGLINTHTHVSMTVFRSLADDVPDRLHRYIFPLEKKLVSRDMVRIGAQLGNVEMLKGGVTTYADMYYFEDEVAKTVDQIGMRAVLGETIIKFPVASAATPEDGIKYTLNFIEQYKDHPRITPAFAPHGPYTNTTEILQKITELSLKHDVPVMTHLAESERENQVIAERSGGLSPIKYMESIGALTPNFVGAHVINANDEDIQILKKHDVGVAHNMSANIKSAKGVAPAMKMFDEGLRIGLGTDGPMSGNTLSTIDEFNQVAKVHKLVNKDRAAMPPKNVIEMATIGAARALHMEDKIGSLEVGKLADVIVVDTKAPNMVPVYNPYSALVYSAYATNVKHAIVDGKLLMENRDVLTVDEEKIRIEAQKYADTVRKTVIESGEIVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2C6</accession>
    <name>D0Z2C6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Efflux pump membrane transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_000577</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 6">Cell inner membrane</location>
            <topology evidence="2 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304752.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000577"/>
    <dbReference type="EnsemblBacteria" id="EEZ39557">
        <property type="protein sequence ID" value="EEZ39557"/>
        <property type="gene ID" value="VDA_000577"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0841">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="145346at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042908">
        <property type="term" value="P:xenobiotic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004764">
        <property type="entry name" value="HAE1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000731">
        <property type="entry name" value="SSD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00915">
        <property type="entry name" value="2A0602"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50156">
        <property type="entry name" value="SSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="341"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="368"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="396"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="441"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="473"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="536"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="874"/>
            <end position="891"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="898"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="926"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="971"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="1004"/>
            <end position="1030"/>
        </location>
    </feature>
    <feature type="domain" description="SSD" evidence="7">
        <location>
            <begin position="371"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ39557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="1051" mass="113491" checksum="D125FD1888D62D6C" modified="2010-01-19" version="1">MLSRFFIQRPKFALVISIILTLAGAIALLNLPVAEYPKISPPSVSVTAIYSGASAEVVEEAVADPIEASVNGVENMIYMSSKSANDGSYSLNVTFDIGTDPDMAQVNVQNRVSQIESKLPAEVRMVGVTVKKRSPDLLMVLNFFSPDGKYDDQFLINYINLNVKDQLARVKGISEVNVIGGGEYAMRVWLDPEKMANLKLTTTDIKNALAEQNVQVAAGKVGAPPYNNAQEVQFNLVTKGRLESAQEFEQVVVRANPDGSIVYLKDVARVELGKKFYDGNGLFNGQPASIVTLSLQSDANALESGQAVMELLSKLKVNMPEGMEYETSYDTTLFVAESIKGVVKTLIEAILLVIAVTYLFLGSMRATLIPVVAIPVSLIGTFAIMLATGFTINTVTLFGLILAIGIVVDDAILVIENVDTNMAKDPTLTPRQATLIAMKEVTGPIITSTLVLLAVFLPVAMLPGITGIMYRQFALTICISVVISSINALTLSPAMCSLVLKQGGDNTARWFKVFNQGLNKITLKYGAIAGFLVRKATLLAAIFVIAVAAVGFYAKTTSTAFVPQEDKGILLVNVQLPDSASLSRTEETTAKLRKIVEAEPAVEGVTIANGYAFLTGAAASNGASMFIKLKPWDERNNMAGDNSSFAITNRINAQAAMTLPEAIVFAMGPPAVPGMGAASGFEFVLEDTLGRSRTDLAEVMGDVIQAANAQPEIQYTFSTFRANVPHFYVDIDRVKAKQLGIPLTEIFQTLQGNLGSMYINDFTMYGKNFRVTLQADSDYRNDLSALERFHVRSSQGDMIPLSTLVTIDQVFEPDVAWRYNMYRSAVIQGGPAPGYSSGDAIAAMERVAAEVLPQGYQFEWTGMAYQEVQAGNQAIYAFALALIFIYLFMVAQYESWSIPLAIILVVPVATLGSFLALAITGIPLNLYAQIGLVLLIALAAKNAILIVEFAKNEREDNNLDIDKAAVRGGKLRFRAVNMTSWSFILGILPLIFASGAGHISQNSLGISLTGGLLCVLLAGTFLIPGFFAVVQRKREKFHGGSTKLVELDDDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2E9</accession>
    <name>D0Z2E9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_000600</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304834.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000600"/>
    <dbReference type="EnsemblBacteria" id="EEZ39580">
        <property type="protein sequence ID" value="EEZ39580"/>
        <property type="gene ID" value="VDA_000600"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1827824at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="9"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="159"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="219"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ39580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="445" mass="51474" checksum="7CE3558177130277" modified="2010-01-19" version="1">MRRLYIESFIGLIVLFGLSLYCYEVIIYRWNTDYDYVLEDYEAEALHDLVDNIYHNEGSKAAYLAIEKYATKTRQTLTVHTKDALPEDVKSFFFTTAPQSYTYHDDDRILWFRLTLSSDFYSLKPNFDTPLRRAIDFDDNMVWVFFMGGFALYSILFIWYLSRRVRLLEKTTLAFAHGEFAARARTESRFRVGTLNQSFNYMADKISNLLISNKALTNAIAHELRTPIFRIQWQAELLADSVKDKEIQQKIESIVEDTEEMESMVNELLYYAKVEQPDTELYCQDIVFNQYLNDMLQNWEKTAQSKITLKTPFKQNIVSSIDTQLFKHVLNNLVSNASRYSRKHILVTLSQERDSVFITVEDDGPGIPNEHWPYLFDPFYSADPARNKAQSGFGLGLAIAKQIVARHKGQITIGDSALLGGAKFTVILPITCQCDPILDRPNISK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2H8</accession>
    <name>D0Z2H8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">RNA polymerase sigma factor RpoS</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_000629</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304914.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000629"/>
    <dbReference type="EnsemblBacteria" id="EEZ39609">
        <property type="protein sequence ID" value="EEZ39609"/>
        <property type="gene ID" value="VDA_000629"/>
    </dbReference>
    <dbReference type="GeneID" id="57342881"/>
    <dbReference type="eggNOG" id="COG0568">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1565734at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000943">
        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009042">
        <property type="entry name" value="RNA_pol_sigma70_r1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007624">
        <property type="entry name" value="RNA_pol_sigma70_r3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012761">
        <property type="entry name" value="RNA_pol_sigma_RpoS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00140">
        <property type="entry name" value="Sigma70_r1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04539">
        <property type="entry name" value="Sigma70_r3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000770">
        <property type="entry name" value="RNA_pol_sigma-SigE/K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00046">
        <property type="entry name" value="SIGMA70FCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02394">
        <property type="entry name" value="rpoS_proteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00716">
        <property type="entry name" value="SIGMA70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RNA_pol_sigma70" evidence="5">
        <location>
            <begin position="249"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ39609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="294" mass="33520" checksum="89B52C4E7977B595" modified="2010-01-19" version="1">MDIKNKVDDTTSFDNDVIQLYLKDIALKPLLTKDEEILYSRKALVGDAKSKKVMIESNLRLVVSIAKKYRGSGMQLSDMIDEGNIGLITAVEKFDPERGFRFSTYATWWIKQTIERAIHNQARTIRLPVHVSKEINTILRTHKQLMKTNNSEPTHEEVADELDKSVEDISALLSYDAPVMSFDQTISSEDSNSQTMASFISDDSDNGPDAQIDKNDIQKLTLTMLEGLNPRDREILCRRFGLMGYEAQTLQQVAEEVGLTRERIRQLQVSSLNKLKNVLQREKYDLELLFAETA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2K5</accession>
    <name>D0Z2K5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Multidrug resistance protein NorM</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Na(+)/drug antiporter</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000656</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304971.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000656"/>
    <dbReference type="EnsemblBacteria" id="EEZ39636">
        <property type="protein sequence ID" value="EEZ39636"/>
        <property type="gene ID" value="VDA_000656"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0534">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1415498at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="34"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="85"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="157"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="184"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="228"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="251"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="311"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="350"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="382"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="414"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00030855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="454" mass="49105" checksum="C102ABAD99AD8A94" modified="2010-01-19" version="1">MKTLIKLAVPLIISQLIAQMLIFTDVWMMAKLSIVAIAGGGLGAAVYSFVFIIASSTVGCVANLIAIAYGKQLRQPEKGEHDVRLALKGGILLAVLLTLSLQPLFYLMKGWLLKAGQDPEAVDLAITYLHAMKWSMLPTLILLVLRSLVSAFSETRSIMVMSLITVILNVPLSYLLAFTLKMGIAGLGYGTSLAAFIVMIGYGYWVFSRPKYRRYMPFRDFHEYRLGIMKPLMVLGIPIMIATMLEHALFSGAALLAGTLGAVSLAIHQIAMQCLNFSWNLAFGLSQAASILVSQHFGKDEPDMVRQYAKLGLGLVTATSAVIGILLSIWPEFLTHVFSIEGDALAEQLVAQLPGVMIMVALCFVVDAWQLSAISILRGMKVVVGPTISTVIGYWFVGLPAAYLLMKWAGLEGIWGGLAIGLAATGVMLVVLLFKNLSAFEKSVAEKAIVAEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2M3</accession>
    <name>D0Z2M3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidyl-prolyl cis-trans isomerase PpiC</fullName>
            <ecNumber evidence="3">5.2.1.8</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000674</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="5.2.1.8" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305024.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000674"/>
    <dbReference type="EnsemblBacteria" id="EEZ39654">
        <property type="protein sequence ID" value="EEZ39654"/>
        <property type="gene ID" value="VDA_000674"/>
    </dbReference>
    <dbReference type="GeneID" id="57343017"/>
    <dbReference type="eggNOG" id="COG0760">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1838755at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000297">
        <property type="entry name" value="PPIase_PpiC"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50198">
        <property type="entry name" value="PPIC_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PpiC" evidence="2">
        <location>
            <begin position="2"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="108" mass="11849" checksum="CB97AE2BE0A852E6" modified="2010-01-19" version="1">MASSAHALHILVKHKELADDILEQLKKGAKFQDLAKKHSTCPSGKKGGDLGEFRKGAMVPQFDKAVFSGKAISTSQALKLKNNNLRGLIPEPVKTKFGWHVIKVLYVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2P1</accession>
    <name>D0Z2P1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000692</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305072.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39672">
        <property type="protein sequence ID" value="EEZ39672"/>
        <property type="gene ID" value="VDA_000692"/>
    </dbReference>
    <dbReference type="GeneID" id="57343038"/>
    <dbReference type="eggNOG" id="ENOG5032X2P">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1848953at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020240">
        <property type="entry name" value="UPF0412_YaaI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10807">
        <property type="entry name" value="DUF2541"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019936" evidence="1">
        <location>
            <begin position="26"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="129" mass="14772" checksum="C6048799BECD79CF" modified="2010-01-19" version="1">MTFKKFFTQLLVGVSLLGSATLAHADDQFTLGRTILLEHGNLAAKIPVPACRYTNAIKVKAERDVRLRKVVVHFQNGEKQTIKFYRDLDKNEKTAWRYFGFRRCVTSLDVYGNSERTTGGIRVYGRKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2T4</accession>
    <name>D0Z2T4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ATP-dependent RNA helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_000735</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the DEAD box helicase family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305202.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000735"/>
    <dbReference type="EnsemblBacteria" id="EEZ39715">
        <property type="protein sequence ID" value="EEZ39715"/>
        <property type="gene ID" value="VDA_000735"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0513">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="626183at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4 8" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="6">
        <location>
            <begin position="31"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="7">
        <location>
            <begin position="224"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="365"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="387"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ39715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="409" mass="45253" checksum="7525F41B689BEA57" modified="2010-01-19" version="1">MSFSTLPLSPSLIHALPNELNTPTDIQRHAIPALVKHQDVLALAQTGSGKTYAYGLPLLQQIDPSQPKIQALILVPTRELTTQVHQSLNTIAEKMAIRTAILCGGISQEQQEETLNSQPQLVIATTGRLLDALSKGQVSLSHIKSWVLDEADRLLDMGFWPDIQKIIQQLPAKRQTALFSATLPEQLESLTQEVLFKPVRIEAQKTNSVVDTISEQLYLVNKGSKPQALIALLKQYPTQQTLVFIGARDNADALCKRLMKAGVQAAALHGHKEQTEREQILADFKAKKLNVVIATDVLARGIHIEQLPLVINFDLPSNAATYVHRVGRTGRAGNNGLALSLVCHGETEFLTAIRQLTQRPLELHNLDGFPVTDKPTTGESKRKPRDKQANRRTAQKRSVKLFKQKPRKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2V6</accession>
    <name>D0Z2V6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cyclic-guanylate-specific phosphodiesterase</fullName>
            <ecNumber evidence="3">3.1.4.52</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">VDA_000757</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>cyclic di-3',5'-guanylate + H2O = 5'-phosphoguanylyl(3'-&gt;5')guanosine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24902"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58754"/>
            <dbReference type="ChEBI" id="CHEBI:58805"/>
            <dbReference type="EC" id="3.1.4.52"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="3.1.4.52" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305263.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000757"/>
    <dbReference type="EnsemblBacteria" id="EEZ39737">
        <property type="protein sequence ID" value="EEZ39737"/>
        <property type="gene ID" value="VDA_000757"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2200">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071111">
        <property type="term" value="F:cyclic-guanylate-specific phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024744">
        <property type="entry name" value="CSS-motif_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12792">
        <property type="entry name" value="CSS-motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0973">c-di-GMP</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="222"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="11">
        <location>
            <begin position="246"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ39737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="488" mass="55658" checksum="259AC43EAECD36E3" modified="2010-01-19" version="1">MTSCIKKILSDKKKLVCTVSLLIWGVFSIALLSATYLSHLASLKERGDLVRVQVEEMLANAQTGINKAVRLDLDNCDNSLYELRNIVAVTPDIRTISLVRNGYMYCNSIIGKLSPERKMGNYQKRLYVRHNSALDHSPVMILTQKISKSQWVRVGISEYYLLRALQRINGDGAVVIKVGDTSYNEFGIIKANLDKYAFYQKSVIYPFSIYLDNNFTIDNKTIIYLLVLAFISFGLALLAMRFITSLNWAKFEVENAIINNKIKPYVQPIVDDNGDIVGGEILARWIKDNGEIVPPNVFIPTIEQYDLMVPMTLSLLNQVIEYQSLYHYKRLHLSFNVTEPCLNDPKIKRVCRSLSRYCDVVLELTENQQLVQTDTAQTMMASMRKFGVKFALDDYGTGYSTLDYLRKIKFDYLKIDKSFVDHITSDDVSNAIIDNIIALADRLNIRIIAEGIEQPEQVEILKSRGVVYFQGYLYGKPMLLDEFASKLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2W2</accession>
    <name>D0Z2W2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cytochrome oxidase biogenesis protein Sco1/SenC/PrrC putative copper metallochaperone</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000763</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SCO1/2 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305277.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000763"/>
    <dbReference type="EnsemblBacteria" id="EEZ39743">
        <property type="protein sequence ID" value="EEZ39743"/>
        <property type="gene ID" value="VDA_000763"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1999">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1994201at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02968">
        <property type="entry name" value="SCO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003782">
        <property type="entry name" value="SCO1/SenC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12151">
        <property type="entry name" value="PTHR12151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02630">
        <property type="entry name" value="SCO1-SenC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="197" mass="22773" checksum="6F3B3BDBD6460107" modified="2010-01-19" version="1">MRYQWLILICALFSGLTAHYFWQKRDPNARHAPYYPMQILEYGEDVIDLFDTTDPRIRVVYFGYTQCPDVCPTSLAILSSALDNLSETQRQNVWPIFITLDPERDTATKTKEYASYFKAGITGLVGTVEQTTELANKYGVLYLKTKMPESKLEYTIDHNSYFYILQPNGNIIKKVAHTLNVQLLTQEINDVLISQKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2Y5</accession>
    <name>D0Z2Y5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fumarate hydratase class II</fullName>
            <shortName evidence="2">Fumarase C</shortName>
            <ecNumber evidence="2">4.2.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Aerobic fumarase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Iron-independent fumarase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">fumC</name>
        <name evidence="5" type="ORF">VDA_000786</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>(S)-malate = fumarate + H2O</text>
            <dbReference type="Rhea" id="RHEA:12460"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="EC" id="4.2.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate metabolism; tricarboxylic acid cycle; (S)-malate from fumarate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="2">There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.2" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000786"/>
    <dbReference type="EnsemblBacteria" id="EEZ39766">
        <property type="protein sequence ID" value="EEZ39766"/>
        <property type="gene ID" value="VDA_000786"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0114">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER01007"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045239">
        <property type="term" value="C:tricarboxylic acid cycle enzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004333">
        <property type="term" value="F:fumarate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006106">
        <property type="term" value="P:fumarate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01362">
        <property type="entry name" value="Fumarase_classII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00743">
        <property type="entry name" value="FumaraseC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005677">
        <property type="entry name" value="Fum_hydII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018951">
        <property type="entry name" value="Fumarase_C_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11444">
        <property type="entry name" value="PTHR11444"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10415">
        <property type="entry name" value="FumaraseC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="SSF48557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Lyase_1" evidence="3">
        <location>
            <begin position="12"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="domain" description="FumaraseC_C" evidence="4">
        <location>
            <begin position="402"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="98"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="133"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="318"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="2">
        <location>
            <position position="182"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="312"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="313"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="2">
        <location>
            <position position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="459" mass="48899" checksum="CD8DBF95DD1A5AEF" modified="2010-01-19" version="1">MGDFRIEKDSMGEIKVPSTALYQAQTQRAVDNFPVSGLVMPVLFIKALAYIKQAAARSNLNLELLDHDIAHAIISSCQEIIDGEHLDQFPIDVFQTGSGTSTNMNANEVIATLASQKLGVSVSPNDHVNMGQSSNDVIPTAIQVSSALGCYTLLFPALEQLSAELEAKKKAIGHIVKTGRTHLMDAMPITFAQELGGWQAQIERAKIGIAQSLANVTQLAQGGTAVGTGINAHPQFAVLFANNLSVATEIPFTASDNFYYNLSSQDAIVSLSGQMKTAAVALLKISNDLRWMNSGPLAGLGEIELEGLQPGSSIMPGKVNPVIPESTAMVAAQVIGNDATITVAGQSGNFQLNVMLPVIALNICQSIELLANTSALLATKAIRTFAIREDNLSQALTRNPILVTALNPIIGYLKAAEIAKKAYKESRPIIDVAEEETDLSREELNKLLHPLHLTQGGIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z305</accession>
    <name>D0Z305_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Dyp-type peroxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000806</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305402.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39786">
        <property type="protein sequence ID" value="EEZ39786"/>
        <property type="gene ID" value="VDA_000806"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2837">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="837319at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006314">
        <property type="entry name" value="Dyp_peroxidase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04261">
        <property type="entry name" value="Dyp_perox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01413">
        <property type="entry name" value="Dyp_perox_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51404">
        <property type="entry name" value="DYP_PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 3" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="313" mass="35461" checksum="45FDDF96806FD8E7" modified="2010-01-19" version="1">MTQNIAELAQAGALSNPSTFAEYLTFVLNENADTESLQDAFSQIAGIEKSIAQKDLTANLNITVAVSKKAWPIVFPDVVMPKHLTTFTEMKDGERQFPSTAGDVFFMIKSERMDLNYQAAKYLLNAFRACADLAEDIQGFKYLDNRDLIDFVDGTENPKNTARINAVLVQDDEEIHHGGSYLTVQRYVDRELKWEKQSTDYQEKVIGRTKLDNIELDDETKPVWAHNNKSKVIIDDEEIKMLRQNRPFGNALEHGTMFIGFAADSNVIETSLRQMIYADSVGYYDRLLDFVDAKSGANYFVLSQTLLDSFDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z332</accession>
    <name>D0Z332_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Chaperone protein TorD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000833</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305476.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000833"/>
    <dbReference type="EnsemblBacteria" id="EEZ39813">
        <property type="protein sequence ID" value="EEZ39813"/>
        <property type="gene ID" value="VDA_000833"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3381">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1995553at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020945">
        <property type="entry name" value="DMSO/NO3_reduct_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036411">
        <property type="entry name" value="TorD-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02613">
        <property type="entry name" value="Nitrate_red_del"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89155">
        <property type="entry name" value="SSF89155"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="217" mass="25977" checksum="85EFD2E56D7C60B8" modified="2010-01-19" version="1">MNKNQIKQNKLDYSDIEITLKLLYQALYFEPTSLLLSEIEDSGILLYLQNKLNIRLSLQNKLINLNNDIDNIQLDHLSLFVGLGMPLAPPWGSIYLNEENLLLRESTYQWLDFLEQQHFQFNLTEQQPYDHIGLMISVISTLWYKLKDDNLNIDFYYHSIRTILSQYLLPWSERFCHLVIEKSQTYFYKYIGNLLYQTLNELKVIFNIDDIEKKLFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z334</accession>
    <name>D0Z334_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000835</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305482.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000835"/>
    <dbReference type="EnsemblBacteria" id="EEZ39815">
        <property type="protein sequence ID" value="EEZ39815"/>
        <property type="gene ID" value="VDA_000835"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1518440at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001737">
        <property type="entry name" value="KsgA/Erm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00398">
        <property type="entry name" value="RrnaAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="271" mass="30833" checksum="C1AD24C4B45B7B6F" modified="2010-01-19" version="1">MPNKLTMPGENHQITKRPGHWVLAQIGKTVLRPGGLELTNKMLNELNITAIDEVIEFAPGVGLTAKMTLAKQPKTYTAVEQNEHAAEIVRSYLNGKNQICHVNSAQDSTLHSEIATVVYCEAMLTMQTTARKKQIMIEAYRLLKTHGRFGIHEMCITPDDIAPHRQRDIQKSLTEAIQHPAKPLTAREWRQLIQECGFDIEYEAMAPMHLLEPTRMIQDEGIIGCIKIFKNLVLKPDVRRRVLSMRNIFREHGRNIAAITFVVKKKEQLNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z375</accession>
    <name>D0Z375_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SgrR sugar-phosphate stress transcriptional activator of SgrS small RNA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000876</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305601.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000876"/>
    <dbReference type="EnsemblBacteria" id="EEZ39856">
        <property type="protein sequence ID" value="EEZ39856"/>
        <property type="gene ID" value="VDA_000876"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4533">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="162819at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025370">
        <property type="entry name" value="SgrR_HTH_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12793">
        <property type="entry name" value="SgrR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SgrR_N" evidence="2">
        <location>
            <begin position="5"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="SBP_bac_5" evidence="1">
        <location>
            <begin position="164"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="562" mass="65088" checksum="409DEEDF1742FA2A" modified="2010-01-19" version="1">MSGQRLKLQFQRLYTHFNGQNSDTNLQDIADVLFCTRRNVRMVINKMVDEGWINWQPAVGRGKQSHLTFHSSDSELQLNHARKLVADGKLEPALSALDNNADKLAQLIQEQLGLSHHLGKQIVRLPYYRSFEALDPLKPLRRSEQHLIRQIFNGLTLINEEKEEVEGDIAHAWEMLSPQHWRFYLRPSVRFHDGKLLDVQDVISTFERVKEHRLYWHIHCVKSPYPNTVDFILSEPDVHFAELVANISAVIQPADAIQRKDFDHFPIGTGPYRVIENNKQRLKLEAFDHYFGFRALTDIVEIWILSGTTACYIKPSEVTEIQPSTLFSGRFTLDEGCNYLLFNRQTGICAQQEWLDYLNAKLTPLNLLKHLDPNELGDFRFTNAYGLLPGWIHNSLAEKEVNVPSKRTITLAYQMEHPIYPYLSTIIAKLLAEDGIKLKTYEISYEDLLSGKGHEKVDIWLNGMSLGSRRPEAFLPWFYNHDFIYQAMPTNEFALLQDDISLWRSLPDKAFPSEKIARHLVNAGQMMPLFYVWVGIDDTGQWQGMESNSMGWFDFKSVWLKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z386</accession>
    <name>D0Z386_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cobalt-zinc-cadmium resistance protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_000887</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305635.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000887"/>
    <dbReference type="EnsemblBacteria" id="EEZ39867">
        <property type="protein sequence ID" value="EEZ39867"/>
        <property type="gene ID" value="VDA_000887"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0053">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="381612at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027470">
        <property type="entry name" value="Cation_efflux_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036837">
        <property type="entry name" value="Cation_efflux_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16916">
        <property type="entry name" value="ZT_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160240">
        <property type="entry name" value="SSF160240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="SSF161111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="115"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="180"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="ZT_dimer" evidence="7">
        <location>
            <begin position="214"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF16916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ39867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="312" mass="34343" checksum="4C9EB5E35F4E5061" modified="2010-01-19" version="1">MSSAQTVQVIRKATWIGSIANIILAVVKIAIGKLTNSQALIADGVHSFSDLVTDAAILIGAKFWTAPADKEHPYGHGRFETLTNIFIGILLALVGIGIGWESLHSISQEQHNSPSLLAFGAAVASIIVKEILYRWTVIQAKKVNSRALFANAWHHRSDALSSLPVAIAVIANYVVPDLHYLDQIAALIVTLMILKAAIEILWPAVKELTDAEADSELEKQIQKLALEDINIKEVHAIRSRRTGSSILIDFHLLVDPEMTIEKAHTIAETFKAKLLDNLDEVVDIIIHIEPFNCAERVMNPCCDDCNETMKEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3C9</accession>
    <name>D0Z3C9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Gifsy-2 prophage protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000930</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305751.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000930"/>
    <dbReference type="EnsemblBacteria" id="EEZ39910">
        <property type="protein sequence ID" value="EEZ39910"/>
        <property type="gene ID" value="VDA_000930"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502ZAF4">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1286271at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009797">
        <property type="entry name" value="DUF1367"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07105">
        <property type="entry name" value="DUF1367"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="195" mass="22424" checksum="979FBC17EEE32A38" modified="2010-01-19" version="1">MAKIALVKTLGGTLVPLTDDDKAIIEKKRVGTVIECDFKTIRNPMFHRKYFALLNLGFDYWEPKGGTVSPAERGLLMRFVKMLAQYGGELQTLQDIASGYLEHLSEHRAQLEIEKSFEAYRKWVIIESGFYDVVVLPNGTTRREAKSISFAKMDDVEFNELYNSSFNVLWNHILNGYFDNRILTEIAVKRLLGYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3F7</accession>
    <name>D0Z3F7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 7">Aldose 1-epimerase</fullName>
            <ecNumber evidence="4 7">5.1.3.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">VDA_000958</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>alpha-D-glucose = beta-D-glucose</text>
            <dbReference type="Rhea" id="RHEA:10264"/>
            <dbReference type="ChEBI" id="CHEBI:15903"/>
            <dbReference type="ChEBI" id="CHEBI:17925"/>
            <dbReference type="EC" id="5.1.3.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Carbohydrate metabolism; hexose metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the aldose epimerase family.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.3" evidence="4 7"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000958"/>
    <dbReference type="EnsemblBacteria" id="EEZ39938">
        <property type="protein sequence ID" value="EEZ39938"/>
        <property type="gene ID" value="VDA_000958"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2017">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1512477at2"/>
    <dbReference type="UniPathway" id="UPA00242"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004034">
        <property type="term" value="F:aldose 1-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006012">
        <property type="term" value="P:galactose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018052">
        <property type="entry name" value="Ald1_epimerase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013458">
        <property type="entry name" value="Ald_epimerase_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015443">
        <property type="entry name" value="Aldose_1-epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008183">
        <property type="entry name" value="Aldose_1/G6P_1-epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01263">
        <property type="entry name" value="Aldose_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005096">
        <property type="entry name" value="GALM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="SSF74650"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02636">
        <property type="entry name" value="galM_Leloir"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00545">
        <property type="entry name" value="ALDOSE_1_EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6 7 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="85"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="182"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="182"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="318"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="254"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00014165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR005096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR005096-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR005096-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR005096-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ39938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="354" mass="39148" checksum="84C05C602CF2C873" modified="2010-01-19" version="1">MNPDIIKLVQTMAQSPSFDGQPAKLVHLTNASGMTASFMDIGATWLSCTVPMPEGAREVLLRSANMDEHMKQTAYFGSIVGRFANRIAKGQFSVDGVDYQLDINNGENALHGGLVGFDKRRWAIEKQTDNQVCFALRSVDGDQGYPGNLDVMVTYTLDEENQLTILYQAHCDASCPVNLTNHAYFNLAGEGSAFNALEHSLQIKAPYYLPADATAIPTGDYKPVVGNSFDFTSLKLIGSEFLQDEDQKLAAGYDHSFVFSEEIVDGKTPVAKLVSPNHDLTMIVKTTKPAMQVYTGNYLLGSIGASKAYQNHDGVALETQYFPDSPNKEQWQQLCPLLLPEQTYHHQTCYQFEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3G0</accession>
    <name>D0Z3G0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 8">UDP-glucose 4-epimerase</fullName>
            <ecNumber evidence="5 8">5.1.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_000961</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>UDP-alpha-D-glucose = UDP-alpha-D-galactose</text>
            <dbReference type="Rhea" id="RHEA:22168"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="ChEBI" id="CHEBI:66914"/>
            <dbReference type="EC" id="5.1.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 8">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 8">Carbohydrate metabolism; galactose metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 8">Belongs to the NAD(P)-dependent epimerase/dehydratase family.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.2" evidence="5 8"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000961"/>
    <dbReference type="EnsemblBacteria" id="EEZ39941">
        <property type="protein sequence ID" value="EEZ39941"/>
        <property type="gene ID" value="VDA_000961"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1087">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00214"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003978">
        <property type="term" value="F:UDP-glucose 4-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006012">
        <property type="term" value="P:galactose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd05247">
        <property type="entry name" value="UDP_G4E_1_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005886">
        <property type="entry name" value="UDP_G4E"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01179">
        <property type="entry name" value="galE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7 8" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="9">
        <location>
            <begin position="17"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ39941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="352" mass="38153" checksum="5CCF5AA3D1D195A1" modified="2010-01-19" version="1">MRNKVFSSLGESKVEILVTGGMGYIGSHTCVQMIEAGITPIIVDNLCNAKEEVLTRIEALTGIRPIFHHGDIRDEAFLDTVFSQHRIEAVIHFAGLKAVGESVAKPLEYYDNNVTGTLVLARSMRKAGVKSIVFSSSATVYGDPDIVPITEDSPTGATTNPYGTSKHMVEQCLSDLFKAEDNWSITLLRYFNPVGAHPSGSMGEDPQGIPNNLMPFIAQVAVGRREKLAVFGNDYPTPDGTGVRDYIHVMDLADGHIAALTAVGKKAGLHIYNLGTGKGSSVLEMVEAFSQACGKAVPFEICPRRAGDIAECWASTTKAERDLGWKATRTVAEMTADTWRWQSENPQGYSLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3M7</accession>
    <name>D0Z3M7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001028</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001028"/>
    <dbReference type="EnsemblBacteria" id="EEZ40008">
        <property type="protein sequence ID" value="EEZ40008"/>
        <property type="gene ID" value="VDA_001028"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3677">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="266" mass="30054" checksum="27E373F821DCF65B" modified="2010-01-19" version="1">MMTMKQDPISNQQCLPPAIHGLQFNHCKTIGCSRFGSTNEDHYVFQRTNPAKPALICRECGAFPPILSNPDVVAEASRLKIAQSSGLPACSNLDCENLGLPVLTHRHLYHAFGYSGDRQRYRCKCCQHTFVDRWSGFNQKHLVQQKLLAMLFTGHSVRDICRRLSMNPKSFYDQLSHIASRCRRQLAMFDGRLFKHAHSLALASDIRPLQPCSDNGVLWIATSEAQSGYVVGQHTNFQPEEVTERFEIHDAYTIGTRFIAPHVSPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3N4</accession>
    <name>D0Z3N4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001035</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306043.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001035"/>
    <dbReference type="EnsemblBacteria" id="EEZ40015">
        <property type="protein sequence ID" value="EEZ40015"/>
        <property type="gene ID" value="VDA_001035"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1661500at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="295" mass="33405" checksum="7BD7E70343AC82E9" modified="2010-01-19" version="1">MDRLSSIEIFVRAVELGSFAVVAEERGISAQMVGKHIRGLESSLGTKLLAKSTRYQALTAAGEQFHLRCLNILSEMNAAQEDIYRNINEPIGKLKLCCGVNLGISLIAPLLGQFIQQYPKLEIELILDNNPPDIQRDGFDVIFHDRVEGYEFLVGHQICSYDMVACASPEYLHKYGIPKHPKELEHHQCLKHSTTYHAHRWCFKGPDGEYFLPRISSRFMINSGQAMLAAAKEGAGITIQPRFQVQNDLNSGSLTHILPSYTLPEIELFMLYKPSLRNTSRLILLNDFFMKSMYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3Q1</accession>
    <name>D0Z3Q1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chlorohydrolase/deaminase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001052</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306090.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40032">
        <property type="protein sequence ID" value="EEZ40032"/>
        <property type="gene ID" value="VDA_001052"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0402">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1592010at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019384" evidence="1">
        <location>
            <begin position="21"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="domain" description="Amidohydro-rel" evidence="2">
        <location>
            <begin position="84"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="478" mass="53102" checksum="E37F94563FFDF506" modified="2010-01-19" version="1">MKLTAVSLISILFFSSSSLASQAQQPYHASLIIKNGQILTMDKNKKVIEDGIIVIDHDKIIAIGEESLLSKYQSEHTIDAKDGIVMPGMINTHNHLPMIAFRGLGEEGIENRLFAYFFPLEKEKLSRNVIYQATRLGTLDLAQSGVTTYADMYYHMDEMAKATKEIGLRAVLGETVIKFPVVDAPKPYGGIEYAKNFIEQYKNDPLITPAFAPHAVYTVSEQKLKEINILSEKLNVPILIHTSEFNNEAERISDNTEKLSPIAWLEKIGVLNNRMVLAHAIHLEPNDINLIKQSGAGVAYNPMANAKGATGIAPAWPMYQQDIAIGLGTDGPMSSNQVDLWRTLSYAANMQRLKYQDRTIMIPEQVIEMATIGGARALHMDKQIGSLEVGKKADIIIVETQSANMHPNYNPYATLVYQANPSNVDTTIVNGKIIMHNRQIMTVEPSDIYQNMSLIEQDITAFAKELAKKAIKSPSLMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3Q8</accession>
    <name>D0Z3Q8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">2-dehydro-3-deoxygluconate kinase</fullName>
            <ecNumber evidence="4">2.7.1.45</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001059</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.1.45" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306110.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001059"/>
    <dbReference type="EnsemblBacteria" id="EEZ40039">
        <property type="protein sequence ID" value="EEZ40039"/>
        <property type="gene ID" value="VDA_001059"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0524">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1604782at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008673">
        <property type="term" value="F:2-dehydro-3-deoxygluconokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00584">
        <property type="entry name" value="PFKB_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="3">
        <location>
            <begin position="9"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="324" mass="36129" checksum="803B1ABE45F180A5" modified="2010-01-19" version="1">MEQLPSLSKKIAIIGECMIELSGQPFVQQEQNFGGDTLNTAIYLSRLLPRLAPAYITALGLDNYSHYMVDAWQKEGINCDYVLRETRKLPGMYAIEIDPNGERSFHYWRNDSAARQMCDHPQFCTAIDYMKSCDLVYLSGISLAILPDHGKIKLLEALAEIRSCGVKIAIDSNYRPRLWRSRMNAKEWMMQLYSLADLALVTAEDEDLLHGSVNSLPSIIAKRLQGQGVEQVVVKMGKEGAQWFELGQSGVVAGNQVDNVIDTTAAGDSFNAAYLASWALGMSMSESCHWGNQLAAQVIQHKGAVIPTAYTRYLTELMDVNYDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3T1</accession>
    <name>D0Z3T1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tagatose-6-phosphate kinase agaZ</fullName>
            <ecNumber evidence="2">2.7.1.144</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001082</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Carbohydrate metabolism; D-tagatose 6-phosphate degradation; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-tagatose 6-phosphate: step 2/2.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.144" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306176.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001082"/>
    <dbReference type="EnsemblBacteria" id="EEZ40062">
        <property type="protein sequence ID" value="EEZ40062"/>
        <property type="gene ID" value="VDA_001082"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4573">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="395879at2"/>
    <dbReference type="UniPathway" id="UPA00704">
        <property type="reaction ID" value="UER00716"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009024">
        <property type="term" value="F:tagatose-6-phosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001059">
        <property type="term" value="P:D-tagatose 6-phosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012062">
        <property type="entry name" value="GatZ/KbaZ-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08013">
        <property type="entry name" value="GatZ_KbaZ-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009264">
        <property type="entry name" value="TagBP_ald_AgaZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02810">
        <property type="entry name" value="agaZ_gatZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="426" mass="47334" checksum="86E9DE4EEA9F4F30" modified="2010-01-19" version="1">MNTLQEIVQSHKAGAKNGIYSVCSAHPLVIEASLLQALDDNSALLIEATSNQVDQFGGYTGMTPSDFRDFVLDKAEQYQFPTEKLILGGDHLGPNRWQDLPASEAMSKADDLIAAYVAAGFKKIHLDCSMSCAGDPVPLSDEIVAERAARLARIAEQTAVATFGSSDVVYVIGTEVPVPGGAAEELDELEVTSAQAATKTIECHRSAFAALGLNCWERVIGLVVQPGVEFDHTGVIDYQPEKAIGLSQVVDQYPQMVFEAHSTDYQTDKAYCQLVADHFAILKVGPALTFAMREALFNLAAIEDELVASAHSSHFKQRIENQMREHPQYWQKYYHGNESQQRFSRCYSFSDRIRYYWPDETILQAQATLFSNLSRYSIPLPLLSQYLPEQFHHVREGLISAEPKALVIDKIRQVLRSYSKACHPNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3Z2</accession>
    <name>D0Z3Z2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Delta 1-pyrroline-5-carboxylate dehydrogenase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001145</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306336.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001145"/>
    <dbReference type="EnsemblBacteria" id="EEZ40123">
        <property type="protein sequence ID" value="EEZ40123"/>
        <property type="gene ID" value="VDA_001145"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4230">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1091139at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="221" mass="24597" checksum="03CA89457034AC1C" modified="2010-01-19" version="1">MMSVSLNAWQHLSLNEKLSQLAPWVESLNTQQQALIHFHCQNIENQVISSVVLTGATGEENTLTLQPKGLVCAVCDKRANELGVLAQVIVPLLMGCSVHLFTYPMEKEQVKSLNLTLLMDLIPSVFSLHLFETLIPFVFAHEVRVISYQGDSGYLLGLQRAILEKEGPLISFMVETQPQTIPILTSCDLWREFISERVLTINVTAIGGNARLLAQTQDSDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z472</accession>
    <name>D0Z472_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">(GlcNAc)2 ABC transporter permease component 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_000328</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304059.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000328"/>
    <dbReference type="EnsemblBacteria" id="EEZ39310">
        <property type="protein sequence ID" value="EEZ39310"/>
        <property type="gene ID" value="VDA_000328"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1173">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1734230at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="107"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="138"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="168"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="217"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="277"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="103"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="313"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="319"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="340" mass="36661" checksum="1BBDE47D85AE6BB8" modified="2010-01-19" version="1">MKTFIKLLTGNLKALTGLCILALFLFVAVFAPVITKHAPDKGTGYPHEYPAFVVKAAKNNPDGWIAKNLATNKRTLMMSRNADHVLGTSRMGRDIWSQVVYGARTSLFVGFGAGILVCFLATFIGVSAGYFGGKVDEILTAAMNIMLVVPQLPLLFIIAAFIGQAGPATIAVVIAITSWAWGARVVRAQTLSIREKEFIKAAEVLGESPWRIIGVEILPNLISIVGASFIGCVLLAIMTEASLSFLGLGDPNAISWGVMLYNVQTSSSMLVGAWWEILTPCLALTFIAIGLSLLNFAVDEIANPQLRSHKGMRRWRDAAQQQAKQTPSNSTPTDTTPQHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-06-02" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z481</accession>
    <name>D0Z481_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000337</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39319">
        <property type="protein sequence ID" value="EEZ39319"/>
        <property type="gene ID" value="VDA_000337"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5033AHA">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="87" mass="9675" checksum="0DB5A913F36C837A" modified="2010-01-19" version="1">MFTVIGAVKQPKKGKKSVEQKQKENILKGLPKNAGLPWAEEERDKLVQAFNTNTSVDELSVIHARTRGAIIAELKKQGLIEEFDSSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4A0</accession>
    <name>D0Z4A0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lysophospholipase L2</fullName>
            <ecNumber evidence="2">3.1.1.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000356</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.1.5" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000356"/>
    <dbReference type="ESTHER" id="lisda-d0z4a0">
        <property type="family name" value="Monoglyceridelipase_lysophospholip"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39338">
        <property type="protein sequence ID" value="EEZ39338"/>
        <property type="gene ID" value="VDA_000356"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004622">
        <property type="term" value="F:lysophospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102545">
        <property type="term" value="F:phosphatidyl phospholipase B activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydrolase_4" evidence="1">
        <location>
            <begin position="50"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="323" mass="37722" checksum="02E2D507BBEAD7CF" modified="2010-01-19" version="1">MNTSAILTKESNFSDLMGCEVRKMWQQRTNGEFLGVRNIPIRWISITKPEHDRCVVIVNGRNESYWKYQELFYELYSHGYDVYAYDHRGQGESGRILKDPQVGYVAEFDYYVDDLDTFIYDVVKPERYKNRYLLAHSMGGAVATLYLERKAKRVFNAAVLNAPMFGISLRFPLTKVASKVARFSELLQPVPSFFWGQKPYQDIPFEKNEQSQSVVRYYWYRHLYKEHPELRVGGPSPRWIWQAIEAANQCVLHANQISTPILLLQAGSDSIVDNHAHERFNSKTPCCRIHVIPGAKHELLMERDGLREQVLADTLRFFEHHNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4C0</accession>
    <name>D0Z4C0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Asp/Glu/hydantoin racemase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000376</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304193.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000376"/>
    <dbReference type="EnsemblBacteria" id="EEZ39358">
        <property type="protein sequence ID" value="EEZ39358"/>
        <property type="gene ID" value="VDA_000376"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3473">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1739382at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026286">
        <property type="entry name" value="MaiA/AMDase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40267">
        <property type="entry name" value="PTHR40267"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17645">
        <property type="entry name" value="Amdase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015736">
        <property type="entry name" value="MI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="265" mass="29059" checksum="DA309E5F358DDFC0" modified="2010-01-19" version="1">MNTLDEFKQFEQPLSYIAAPRIDRTHIGLVQLSTDHSLEMDWAKLLGSQAAVFSTRIFYNSEMTPEALDNIASGISEGSDLIAYGLPMDVMAFGCTSASIIIGEERVAQLLTENRGNIPATNPWTAAKAAFKHLGAKKIAVFSPYPTEVNFPLYQQLTNAGFEVVVLGSLGIERDTDITTVSKESMLTALAQILPNSGADLVFMSCTNLRVLDHIQEIEDQFNIPVVCSNSAMFWHALHLTGKTASCPGYGRLLNLTEQRNLDVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4G5</accession>
    <name>D0Z4G5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000421</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304321.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000421"/>
    <dbReference type="EnsemblBacteria" id="EEZ39403">
        <property type="protein sequence ID" value="EEZ39403"/>
        <property type="gene ID" value="VDA_000421"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2357">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1614527at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019404" evidence="1">
        <location>
            <begin position="26"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="263" mass="29632" checksum="F72F6185341527A7" modified="2010-01-19" version="1">MTVKTIARTCFVLVAVFGRMPIASAAPVMQVDDAPLKLSALERNAQPELQQSIRGLFSIPSWRQHQIQQPFAQFDELYQHAEVAQHEMISLLSKTQKITETQIILPGLKGKLRAQEKIESELGGQADKLTDIVRASIVADSIPDLVKAYDEITQHSTLLEVNNRFATPAKSGYRDLKLLVRLPESKHIAEIQLHLSAIAEVKSGPEHKIYEEVQGIERLAQQQNRALNDIEQATIDRLRATSQRLYQESWQHYLSPQKNAVNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4H6</accession>
    <name>D0Z4H6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000434</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000434"/>
    <dbReference type="EnsemblBacteria" id="EEZ39414">
        <property type="protein sequence ID" value="EEZ39414"/>
        <property type="gene ID" value="VDA_000434"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4719">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001434">
        <property type="entry name" value="DUF11"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01451">
        <property type="entry name" value="B_ant_repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="200" mass="22608" checksum="F4652B82C1AB4BEB" modified="2010-01-19" version="1">MGSSFVEYFNALNLLIFIVFSLGMLIAFRLVLCINMMRCNVKSLLFLFLLSLTTSFSAFADDKEPLVSQMDAYLIEVNKDGDEVLKPADTVYPKDKIEYKLTYTNNSKGALDGLVITGPIPQNTVYVGDTDKTKVKSKFVVSIDGGKTFEPEPVKREVMKDGKKVEVIIPPEKYTAVRWIPEVPINSKEKQIFTYRIEVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4S2</accession>
    <name>D0Z4S2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Hydroxymethylpyrimidine ABC transporter transmembrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_000530</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304639.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000530"/>
    <dbReference type="EnsemblBacteria" id="EEZ39510">
        <property type="protein sequence ID" value="EEZ39510"/>
        <property type="gene ID" value="VDA_000530"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0600">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="916788at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="26"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="111"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="142"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="190"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="233"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="72"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ39510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="267" mass="29587" checksum="CAF6B77C39B2C474" modified="2010-01-19" version="1">MSELSPVDLNNQSRQRKILTPAYLQPYIRVVVTLGLLLCLWQGTIWLFSLPSFILPSPIAVLDRLYYRHDVLLHHTWITGCEIILGLALGLLMGLFFALLMLLFAPVKRWLLPILIASQAIPVFAIAPILMLWLGYGMASKIVMAGLIIFFPVTTCCFDGLRHTPQGYLDLAKTMGATPWQLLKTIRLPAALPALASGIRVAVVIAPIGAVVGEWVGSSEGLGYLMLQANARMMIDEMFAALTILALLSISLYYLTDKLLKKLIPWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4U4</accession>
    <name>D0Z4U4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000177</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39161">
        <property type="protein sequence ID" value="EEZ39161"/>
        <property type="gene ID" value="VDA_000177"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="164" mass="17481" checksum="D3C94920ECF8ED0D" modified="2010-01-19" version="1">MATTTACALPLVTLVPIRQILPISSRLLSLFGSGSLSHPLPETLARTSYFSTGSDSPLSIDWLTNRSRDSSRRTSAGTRSPAARKMISPGTSSSMAISSCTGPIFPGPRRSTVAVVRTMDFSACAALLVRNSCQKRNNPLRLTIVTIMMIPVRSVSSPLRSGSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4Y0</accession>
    <name>D0Z4Y0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000213</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39197">
        <property type="protein sequence ID" value="EEZ39197"/>
        <property type="gene ID" value="VDA_000213"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="388" mass="42463" checksum="9B9583D70B8BC5D0" modified="2010-01-19" version="1">MQISIRTDGAAGTAALLSSQQTPSAANTSLSQVSSVSVSLVGNQPPLNTKPVSLPPLRQAVEEFNHAIMRAAQYDGSIENLVRDKVNAQFPAASDAVKNQIVAQSVEKIAEANQAFEFNHLGNDLLQSPAVEYMSQSFLRRILENVAIAQAKDPSVLVAKTNEDAGIGFLDGWSDDDAKWAEQLNSVLNDPKANARVLTTLAYSHLRVFRDPSRLKLMGDTVNQPLLNAKEANQRLNIFHLHGAGAKPEISTPITTQPHGWAWLKYADWNTSEALGNKTGNNFIGSRQNDDPHKGTRFKLQGMQEVMKPAAYHNDAVALKERPEHESGYGGFVINDKTLTTIGQDEPTSVNWRQQNMDKKLPMFAGPSSTTSFMYEVARLLKMPASEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z518</accession>
    <name>D0Z518_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-acetylmuramoyl-L-alanine amidase</fullName>
            <ecNumber evidence="2">3.5.1.28</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000251</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.5.1.28" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306737.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000251"/>
    <dbReference type="EnsemblBacteria" id="EEZ39235">
        <property type="protein sequence ID" value="EEZ39235"/>
        <property type="gene ID" value="VDA_000251"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3023">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1584918at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008745">
        <property type="term" value="F:N-acetylmuramoyl-L-alanine amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009253">
        <property type="term" value="P:peptidoglycan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06583">
        <property type="entry name" value="PGRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.101.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036505">
        <property type="entry name" value="Amidase/PGRP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002502">
        <property type="entry name" value="Amidase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036365">
        <property type="entry name" value="PGBD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036366">
        <property type="entry name" value="PGBDSf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01510">
        <property type="entry name" value="Amidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00644">
        <property type="entry name" value="Ami_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47090">
        <property type="entry name" value="SSF47090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55846">
        <property type="entry name" value="SSF55846"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetylmuramoyl-L-alanine amidase" evidence="1">
        <location>
            <begin position="7"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="256" mass="29481" checksum="6102F05F67D3B582" modified="2010-01-19" version="1">MCKIDYNSYRSVKGFNRRIRFIVMHYTAADFFSSVKLLAGDGGVSAHYLVPDPTEKNYINSGFKDMRIFNLVDESDRAWHAGISHWQGRSSLNDTSIGIEIVNLAKYEHGEFIFPPFKQEQIEAVKTLALNIIQRYPDISPINVIGHSDIAVGRKSDPGPLFPWFELYQFGVGAWYDDETKDKYLIQFHKEGIPIQKDIISKMNAYGYDISNANTNDGYQKLVRAFQLHFRQKNYDGRMDNETAAILYSLVDKYIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z532</accession>
    <name>D0Z532_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">IncF plasmid conjugative transfer DNA-nicking and unwinding protein TraI</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000265</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306775.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000265"/>
    <dbReference type="EnsemblBacteria" id="EEZ39249">
        <property type="protein sequence ID" value="EEZ39249"/>
        <property type="gene ID" value="VDA_000265"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0507">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="961809at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014059">
        <property type="entry name" value="Conjug_relaxase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014129">
        <property type="entry name" value="Conjug_relaxase_TraI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040668">
        <property type="entry name" value="TraI_2B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014862">
        <property type="entry name" value="TrwC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18340">
        <property type="entry name" value="TraI_2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08751">
        <property type="entry name" value="TrwC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02686">
        <property type="entry name" value="relax_trwC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02760">
        <property type="entry name" value="TraI_TIGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TrwC" evidence="2">
        <location>
            <begin position="14"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="TraI_2B" evidence="3">
        <location>
            <begin position="691"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1954"/>
            <end position="1975"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF18340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="1975" mass="221481" checksum="B1C52B8ECA840879" modified="2010-01-19" version="1">MLSLSSLRGGASGASKYYLEEEKQLNLNQPQFTLKPDTQPTKESLLAPTDYYLAEQSGTEKTTQWYGKIAEKEGILGHKIEHQKLEAVLNGQLNNDHTPRAHSDTRRTGYDLVFSAPKGASILALVYGDTRIIDAHNAAVKTALNLMEQDTAQAKVAENKERRFENTQNLLFGLVQHKTSRENDPQLHTHALQANMTYDKQGSLKNLASSSVQNGFETQGTYERILENQKYYGMAYQSELGRALEEMGYAIKSLGNSQIDIDGIPDEVIDANSARRQQILEQEQELGIKSGKARDHIAHQTRKAKTYTPEDSLIKEWQVKNIKLDFNGLEFVADSYNGKHRKESNLSVPDEKLQQAIENSISYLSDRLSAFGYEKVLVTALDKFAPKAITQIGGLKQVLDSKIKHGDLIALDNKQSLFTTQEQVDREAKLIESTQKRAHGLRVHAESTALNELNLKADTKKTLADILASTKQVNVVNLSGSSKQLSESLLHVSENSGKSIHFITPNKLVKQQTEQQVKRQAFSVTQWVKNAFRPDVVHTTYQYLNQAEQRQKTKDSILVIEHANQLGVKETQQLIDLAQHQGNKLVFLNHTKRSQGLRAGNAMEVVQKGNVRTHIWQGAQLAQTQIKTSEVDKKERHQILAERYQALSKQERSETQVLTTNKSDSDNLNRVIRHQLDKSGQLSEKRVEIPTLNPVFMSPEQQRSIKSYQKGMVISQVNDGKVERYTVEKVNSRAQTLQLLDGDNNRSYVNVKENTTPYFVSQPAKIEVATGDRLRINGDVFRTDLKQNDTVTVEKIGWLGLSLKDDNGKGHLVPLSYLEDSALSYGYANTLNNATHGKTTTLIDMQSYTASKEALYELMQQGSKQLHIFTDNQEKLESRMEKSHIQPSSMARVMASTQSLDKYVNAQTVDTLQSDVTVAMQALLNQQAPKPLIEQAVNFALSHVSEQQAGFKHSELVVEAIRFAMDEKGTTVLESEIHKKLNELQQQDSVLSAQFSDGTRWTTQEAIETEKRILTRLDAGKGQVASYASERQADAYLAQQDWMTDGQKDAVKLMATTHDRYTIVQGFAGVGKSTMLEQGKTLIEQTQALRGNAKIEILGLAPTHAAVNELKEKGIPAQTTQSLLKDLLMGDTTPDRYRNTLFLLDESSMASNAQFDAFTALVNNAGARATFLGDIYQLQSKEAGKPFELAYRTKSIDTVVMKDIKRQQTPELLSAVQNVINQQPESMLEAIKQQSPLHGSHHNQTVISTYNDTGNSAKDREVAKEELYQSAAAEYLSRTPESRENTLMIAYSNRERDILAGLIRKGLKEMKELPDKSDTPVTRLRGIGTTKEELKTMMPYKAGLIINTGRDNYLHIDSIDRRNELLMVTNMTTGEQTAFIPAKHDHKMTTLWIGSEMPLTSGDKITWRKTDKELGLTGNTDLTVSSINKDTMTLSYDKDKTITLPLNDMKSSHWDYRYTKTADMAQGSTMNHVISVIDSGAKLTNLRRAYIDISRASQHAMIFTDNEKGLMRSWLNHFDNNSSAIETINQTNHPNEHHFDVQSIPKENPKYQQHGEFKLSLYAKDLAQQLTPYTESLAIELLGQPNNSKSDNDYLAFGRGKSHLKVTLTGEYRGYYRDWTTGDKGNLINLIMSAKSFSFKEAVNFAEQILTEPENHNLIENEKHDKLVNTLPKHVGNLKARAINYFEQGVELKETIANTYINNQTYHDFESHPALRFHEQVYSSETKSTHPALLAALTNNKGEIEAIEITYLNKDGDLADNLTIPKRLMGNKSGHGIVLNDGTLPDISVVAIGLENGISLLGANTHDVDIVAVNNAHDLRTLDTKALREQIIIMANESQLSNQNLINDITDKLTAQGHSVSIVKEAIDGLSPQDIGILISDKVNDDIAELKGKHEFDTNKIVQLVDDINKSQEFSDKEMASLLDVIEPKGIEHANNLANEVVDKALAEYDLHQEQTERELTQEKELEKEMDYPSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z558</accession>
    <name>D0Z558_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Putative phosphoenolpyruvate synthase regulatory protein</fullName>
            <shortName evidence="5">PEP synthase regulatory protein</shortName>
            <shortName evidence="5">PSRP</shortName>
            <ecNumber evidence="5">2.7.11.33</ecNumber>
            <ecNumber evidence="5">2.7.4.28</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Pyruvate, water dikinase regulatory protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_000108</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>[pyruvate, water dikinase] + ADP = [pyruvate, water dikinase]-phosphate + AMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46020"/>
            <dbReference type="Rhea" id="RHEA-COMP:11425"/>
            <dbReference type="Rhea" id="RHEA-COMP:11426"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43176"/>
            <dbReference type="ChEBI" id="CHEBI:68546"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.33"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>[pyruvate, water dikinase]-phosphate + H(+) + phosphate = [pyruvate, water dikinase] + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:48580"/>
            <dbReference type="Rhea" id="RHEA-COMP:11425"/>
            <dbReference type="Rhea" id="RHEA-COMP:11426"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43176"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:68546"/>
            <dbReference type="EC" id="2.7.4.28"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.33" evidence="5"/>
    <dbReference type="EC" id="2.7.4.28" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306871.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000108"/>
    <dbReference type="EnsemblBacteria" id="EEZ39092">
        <property type="protein sequence ID" value="EEZ39092"/>
        <property type="gene ID" value="VDA_000108"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1806">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="980472at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016776">
        <property type="term" value="F:phosphotransferase activity, phosphate group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006470">
        <property type="term" value="P:protein dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01062">
        <property type="entry name" value="PSRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005177">
        <property type="entry name" value="Kinase-pyrophosphorylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026530">
        <property type="entry name" value="PSRP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31756">
        <property type="entry name" value="PTHR31756"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03618">
        <property type="entry name" value="Kinase-PPPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="157"/>
            <end position="164"/>
        </location>
        <ligand>
            <name>ADP</name>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ39092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="278" mass="31962" checksum="1D81C11070AEBDC8" modified="2010-01-19" version="1">MKIKPQSRDVFYVSDGTAITCETLGHVVLSQFPFVPNEKTFPFVESEDKVTDVIKEIEISFQKNGVQPLVFFSIVVPEIREILLKAPAYKYDVLESIVQRVQDDIQMDPQPKMQRSRSVKKNSDTYFDRIAAIEYTLAHDDGLTLKGLKEADIILLGVSRSGKTPTSLYMAMQFGLRVVNYPFIAEDINTMRLLPEFEIYRHKLFGLTINPDRLNEIRENRLSGSEYASTEQCKLELDTVEALFRREAIPYIDTSFLSVEEITTRILERAGTKRRLFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5A8</accession>
    <name>D0Z5A8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Membrane-fusion protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000158</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005307010.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000158"/>
    <dbReference type="EnsemblBacteria" id="EEZ39142">
        <property type="protein sequence ID" value="EEZ39142"/>
        <property type="gene ID" value="VDA_000158"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0845">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1532186at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HlyD_D23" evidence="3">
        <location>
            <begin position="58"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="97"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="378" mass="40788" checksum="C7C6B6B3BADF4A3A" modified="2010-01-19" version="1">MAKTWLVATVSIALLGGSVYFYLQSSAQPREFSTLIVEKRTIEKRAVAVGNIVPAHSISIKSQINGIVGEIYVKVGEKVKQGQPLIKVRPNPTPQALTDASTDLMRSEADLESAKQKLANLESLVKQNIIPKNYDGYVSVRSEVKSAQANVLQKRQNLELIRSGEASIGNSRLTSTIYAPVDGTVLNRKVEVGEPIISTEASQAATEMMSLADMNSLIFKGSVSEHDAAQLSPGMPVLLTLAPYPDVEISGVLTKVAIQSENLNSPEGNKAAKSFDNGFGVEVGDLVIPQEMMLRSGFSSTAQISLKKLENVLTLPERALQFDGDTPNVLIPDSSKQGYHKQKVKLGLSDGINVEVLDGVELDEKIIDNSMMMGAVHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5E3</accession>
    <name>D0Z5E3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000005">
        <property type="protein sequence ID" value="EEZ39065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39065">
        <property type="protein sequence ID" value="EEZ39065"/>
        <property type="gene ID" value="VDA_000050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008160">
        <property type="entry name" value="Collagen"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01391">
        <property type="entry name" value="Collagen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="51" mass="4835" checksum="6B747C1E29E521C1" modified="2010-01-19" version="1">MLSFAGFAGFAGFAGFAGFAGFAGFAGFAGFAGFAGFAGFAGFAGFAGSIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVK4</accession>
    <name>D0YVK4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001584</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298327.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001584"/>
    <dbReference type="EnsemblBacteria" id="EEZ40558">
        <property type="protein sequence ID" value="EEZ40558"/>
        <property type="gene ID" value="VDA_001584"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502Z7JD">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1737534at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021372">
        <property type="entry name" value="DUF2989"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11207">
        <property type="entry name" value="DUF2989"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="283" mass="33222" checksum="1E3C8248C1F16726" modified="2010-01-19" version="1">MRLSIDRYSLYQITAICLCILPLQGCFERHKTTDRLCQEKPQLCHDLNIDDGQCRIQRTNLIWQRNRILSAPTDIERLQELKDMKKYQLCLEFAAQIEPIDMKERKTYRIDKLHQVYQSEQKLMEQLLNSYDPNVLYYRWTQGSQDALEQFLKQEDSEQVKTTTLQFGYAAYYSQQKNSNKAKQHLLAALSYLEPNEAIQPQLIQGLATYAFQENNLIQAYIWTRTGQQLKLFDVSDQRMEQHFSFSSKEISTLDKVVDKVVNSLLDGNFEPALLIVPTFKNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVM5</accession>
    <name>D0YVM5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001594</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40567">
        <property type="protein sequence ID" value="EEZ40567"/>
        <property type="gene ID" value="VDA_001594"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="37" mass="4248" checksum="F5081017A1E1086B" modified="2010-01-19" version="1">MAKHIMMDIAKILKECIESYGMRKVGMTVLNSVMMLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVW9</accession>
    <name>D0YVW9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_001250</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the UbiH/COQ6 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297728.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001250"/>
    <dbReference type="EnsemblBacteria" id="EEZ40228">
        <property type="protein sequence ID" value="EEZ40228"/>
        <property type="gene ID" value="VDA_001250"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0654">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016709">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018168">
        <property type="entry name" value="Ubi_Hdrlase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010971">
        <property type="entry name" value="UbiH/COQ6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01988">
        <property type="entry name" value="Ubi-OHases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01304">
        <property type="entry name" value="UBIH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="8">
        <location>
            <begin position="5"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ40228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="401" mass="44330" checksum="88D2488883A5D2B2" modified="2010-01-19" version="1">MMQNVDIAIIGGGMVGLTLAAALADTELRIAVIEGQLPDETLAELPDLRVSALSRASERILRRVGAWSGIESRRLSPYQHMEVWEQDSFANIQFSAERLAQPNLGHIVENRVIQLALLEQVKKQHNVTLLAPERCDNIVFGESEAWLTLSSGKHLTAKLVVGADGANSWLRNALNIPLTHWDYGHSAIVANIRCGEPHLATARQIFRPQGPLAFLPLSEPNLCSIVWSTEPKEAERLCAMSDEQFNQYLTTAFDGRLGLCQIEGQRQAFPLRMRYARDFVKDRVALIGDAAHTIHPLAGQGVNLGLLDAVALAQELKQLWLEQKDIGSKANLRHFERWRKAEAAKMIAAMQGFRDLFAGSHPAKKLLRDIGMLVADKAPGLKDELMRKALGLSGELPDLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVY8</accession>
    <name>D0YVY8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phosphorelay protein LuxU</fullName>
            <ecNumber evidence="4">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">VDA_001267</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 23">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297754.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001267"/>
    <dbReference type="EnsemblBacteria" id="EEZ40245">
        <property type="protein sequence ID" value="EEZ40245"/>
        <property type="gene ID" value="VDA_001267"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0784">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004721">
        <property type="term" value="F:phosphoprotein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00088">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019247">
        <property type="entry name" value="Histidine_kinase_BarA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036641">
        <property type="entry name" value="HPT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008207">
        <property type="entry name" value="Sig_transdc_His_kin_Hpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01627">
        <property type="entry name" value="Hpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09984">
        <property type="entry name" value="sCache_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00073">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47226">
        <property type="entry name" value="SSF47226"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50894">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="16" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 22" id="KW-0418">Kinase</keyword>
    <keyword evidence="17" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 15" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="13" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="6"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="174"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="20">
        <location>
            <begin position="197"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="18">
        <location>
            <begin position="296"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="19">
        <location>
            <begin position="668"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="domain" description="HPt" evidence="21">
        <location>
            <begin position="826"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="248"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="15">
        <location>
            <position position="717"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphohistidine" evidence="14">
        <location>
            <position position="864"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="EEZ40245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="921" mass="102842" checksum="150352607ABE2DE7" modified="2010-01-19" version="1">MTRYGLRARVFTLTLAPTLIIGLLLSAFFTLSRYQDLEHQLISTGTSIIEPLAISAEYGMTDKNREAVRRLISYAHRKHSNIVRSIAVFDAHNQLFVTSNFHRNFEALMYPPDKPIPPLLETELRDNALIMRAPILTEGQFGPHADPSLRGTPLGYISLELDLSALRLQQYQEVFTALMVLLLGLTLSSLFAYRLMQDVTRPISHMVSVVDRIRRGHLDIRIEGRLLGELDTLKNGINAMAISLSEYHVEMQQSIDQATSDLRETLEQLEIQNVELDIAKKRAQEAARVKSEFLANMSHELRTPLNGVLGFTRQMLKTRLNPSQQDYLLTIEKSANNLLTIINDILDFSKLEAGKLLLENIPFDFAESLDEVMRLLAPTAHEKGLELTLKVDDRIPPSLIGDALRIQQVLTNLIGNAVKFTERGNIDVTVELKSDKDDEGIELQFMVRDTGIGISERQQAQLFQAFSQADASISRRYGGTGLGLVITQKLVSQMGGEVSLTSRLHQGSTFWFTVRLTKTDLPVSQLIDTSSLSGKKVLLIEPNMQAASVIQQRLINVGVHVTYRSVMPEDVERHDYTLLCLSPGEQPPIATLIDQVFKAEQMTDNVIVCLPTTELALSERLVNAGVSACLGKPLSQRRLFEVMCGDNEQMEPEQPLLPEPASPIQPLTVMAVDDNTANLKLISALLCERVETVITATGGRKAVEYAKQKAFDLIFMDIQMPEMDGVTACQQIHDTELNRTTPVIAVTAHAMAGERERLINAGMDDYLTKPIEEHILQQVLGRWIAPIESQIEPQALIAPLPTSVESVPKQDISFDWDLALKQAAGKEDLARDMIQMLLDFMPEVEMLVNEALDGKEVDLWPPIHKLHGSCAYSGVPRLKNLCHTIETALKGNASNEDIEPELFELVDEMENVVRASKAYRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW04</accession>
    <name>D0YW04_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Signal recognition particle protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Fifty-four homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ffh</name>
        <name evidence="9" type="ORF">VDA_001309</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="7">The SRP-RNC complex is targeted to the cytoplasmic membrane.</text>
    </comment>
    <comment type="domain">
        <text evidence="7">Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the GTP-binding SRP family. SRP54 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297844.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001309"/>
    <dbReference type="EnsemblBacteria" id="EEZ40284">
        <property type="protein sequence ID" value="EEZ40284"/>
        <property type="gene ID" value="VDA_001309"/>
    </dbReference>
    <dbReference type="GeneID" id="57339799"/>
    <dbReference type="eggNOG" id="COG0541">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="656414at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048500">
        <property type="term" value="C:signal recognition particle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008312">
        <property type="term" value="F:7S RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00306">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036891">
        <property type="entry name" value="Signal_recog_part_SRP54_M_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013822">
        <property type="entry name" value="Signal_recog_particl_SRP54_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004125">
        <property type="entry name" value="Signal_recog_particle_SRP54_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004780">
        <property type="entry name" value="SRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022941">
        <property type="entry name" value="SRP54"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000897">
        <property type="entry name" value="SRP54_GTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042101">
        <property type="entry name" value="SRP54_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11564">
        <property type="entry name" value="PTHR11564"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11564:SF7">
        <property type="entry name" value="PTHR11564:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00448">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02881">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02978">
        <property type="entry name" value="SRP_SPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00962">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00963">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47446">
        <property type="entry name" value="SSF47446"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00959">
        <property type="entry name" value="ffh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00300">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 7" id="KW-0733">Signal recognition particle</keyword>
    <feature type="domain" description="SRP54" evidence="8">
        <location>
            <begin position="269"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="107"/>
            <end position="114"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="190"/>
            <end position="194"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="248"/>
            <end position="251"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ40284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="455" mass="50099" checksum="BF4FA4ECAE406E4E" modified="2010-01-19" version="1">MFENLTERLSRTLKNVSGRGRLTDDNIKDTLREVRMALLEADVALPVVREFVNRVKERAVGTEVSKSLTPGQEFIKIVQAELEAVMGEQNEELNLASQPPAVILMAGLQGAGKTTSVGKLSKVLKERNKKKVLVVSADVYRPAAIKQLETLATDLGVDFFPSTPDQKPVDIAKAAVAHAKLKFYDVLIVDTAGRLHVDSEMMDEIKDVHQVLNPVETLFVVDAMTGQDAANTAKAFNDALPLTGVILTKVDGDARGGAALSVRHITGKPIKFLGVGEKTDALEPFHPDRVASRILGMGDVLSLIEDIERNVDKDEAEKLAKKFKEKKGFDLEDFRSQLQQMKKMGGMMGMLDKLPGMSQLPGDVKDKVDDKIFVQMEAIINSMTPGERERPDLIKGSRKKRIAAGSGTQVQDVNRLLKQFTQMQKMMKKMQKGGIKNMMRQMKGMMPGGGMFPGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-12-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW23</accession>
    <name>D0YW23_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Site-specific recombinase phage integrase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001285</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297790.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40261">
        <property type="protein sequence ID" value="EEZ40261"/>
        <property type="gene ID" value="VDA_001285"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0582">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="745068at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0229">DNA integration</keyword>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyr recombinase" evidence="3">
        <location>
            <begin position="11"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="198" mass="22997" checksum="D4B1B15BBC04DF2F" modified="2010-01-19" version="1">MSAWNKGKRVGQKKAFKLEDIWRIRIRLELEERLFELALFNLAIDSKLRSCDLRNLKVQDVSRSGCVMSRTIVKQQKTQQEVHFEITPKTQQTLSQWIIQNALAPTDFLFPSPRREGQPISYHYYSTLVNRWVTDIGLDKTQYGTHSLRRTKASLIYAKTKNLRAIQLLLGHAKLESTIEYLGVEIEDALRISESCET</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW30</accession>
    <name>D0YW30_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001293</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297811.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001293"/>
    <dbReference type="EnsemblBacteria" id="EEZ40268">
        <property type="protein sequence ID" value="EEZ40268"/>
        <property type="gene ID" value="VDA_001293"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="237" mass="26748" checksum="82CCA78E8C26B710" modified="2010-01-19" version="1">MKKHQSKVLSQNHNATKKRAATLEQVKLRISLLNDFIENGVPDGFTAHTGLLKLLAYSDGGEIEQRSYQSILSKKNIPIIDIDPSFKGSASAVIDCKDYLLLKIDKLKKLEMPCVPLEQSNDAAFDSSLNTPKTKTKGELKGTIKEQAALIESLAKELLKQRRANNTLISVIRERDRHASRTLKAYFDKHQDDLCQVREFIKPSLEKTISNLHELSREFDEAFGDNEDSIVQILGER</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW42</accession>
    <name>D0YW42_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Outer membrane protein assembly factor BamD</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">bamD</name>
        <name evidence="3" type="ORF">VDA_001322</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the Bam complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the BamD family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297858.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001322"/>
    <dbReference type="EnsemblBacteria" id="EEZ40297">
        <property type="protein sequence ID" value="EEZ40297"/>
        <property type="gene ID" value="VDA_001322"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4105">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1256747at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043165">
        <property type="term" value="P:Gram-negative-bacterium-type cell outer membrane assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051205">
        <property type="term" value="P:protein insertion into membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd15830">
        <property type="entry name" value="BamD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00922">
        <property type="entry name" value="OM_assembly_BamD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017689">
        <property type="entry name" value="BamD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039565">
        <property type="entry name" value="BamD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13525">
        <property type="entry name" value="YfiO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03302">
        <property type="entry name" value="OM_YfiO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5009009100" description="Outer membrane protein assembly factor BamD" evidence="1">
        <location>
            <begin position="22"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="YfiO" evidence="2">
        <location>
            <begin position="26"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="242" mass="27888" checksum="6D3D7B287D9EF5DF" modified="2010-01-19" version="1" precursor="true">MKRLTLTTLLAVAILSGCSSTEEVVPDVPPSELYATAQESLQSGNWSQAIERLETLDSRYPFGAYSDQVQLDLIYAYYKNDDLAMSEATINRFMRLNPINPKSDWVLYMLGLTHMAQDRSFMHDLFNVDRSDRDPTAARQAFRDFQVLLQRYPNSEYSADAKARMVFLKNRLANYDLAVADFYIRRGAWIAAINRCEQVQRLYDDTEAARKSLLLEKKAYEKLGMQKEVERTQKSIDLNPVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW50</accession>
    <name>D0YW50_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001332</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297869.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001332"/>
    <dbReference type="EnsemblBacteria" id="EEZ40307">
        <property type="protein sequence ID" value="EEZ40307"/>
        <property type="gene ID" value="VDA_001332"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2818">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1591712at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008725">
        <property type="term" value="F:DNA-3-methyladenine glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005019">
        <property type="entry name" value="Adenine_glyco"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03352">
        <property type="entry name" value="Adenine_glyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="SSF48150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="229" mass="26101" checksum="A8C94805C40C9A84" modified="2010-01-19" version="1">MVREKFNQIYDRAAERKGGIQALEKLLVVPKSQQELALITDDRWLATFTLRIFQSGMTWQVVRNKWPNFEDVFFGFNIEKMLLVPDEMWERKATDPAIIRHLGKVMTIPANADMIHRAAVEYGSFAQMVADWPCEDIIGLWQYLKKKGSRLGGNTGPYALRTMGKDTFIISQDVEAYLRNIGVIEGGKSSLKSLKATQTAFNDWQQESGRPMCQVSQIISFSCGDNHVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW59</accession>
    <name>D0YW59_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001344</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297889.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001344"/>
    <dbReference type="ESTHER" id="lisda-d0yw59">
        <property type="family name" value="NLS3-Tex30"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40319">
        <property type="protein sequence ID" value="EEZ40319"/>
        <property type="gene ID" value="VDA_001344"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3571">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1090356at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026555">
        <property type="entry name" value="NSL3/Tex30"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13136">
        <property type="entry name" value="PTHR13136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="232" mass="25582" checksum="E30A7BBB3BB519B4" modified="2010-01-19" version="1">MSSEYLICGPESSDAVATFLFAHGAGAGMDHEFMTEMAVELAKYRIQVIRFNFPYMVKRAEDGKKRPPDRQPKLLHDFKQHIDAVDNGKLVIGGKSMGGRMASLMVTDTATQAANIANCCDIVKGVACLGFPFHPPGKPDNFRGDHFANMQTPTLILQGERDTFGTRTEVEAMVFSSHVSIQYLPDGDHSFKPRKASGYTLQQNMAQAANGLAQFIYQCVGACWNPLQNEEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW70</accession>
    <name>D0YW70_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">tRNA pseudouridine synthase C</fullName>
            <ecNumber evidence="2">4.2.1.70</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001355</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="4.2.1.70" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297909.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001355"/>
    <dbReference type="EnsemblBacteria" id="EEZ40330">
        <property type="protein sequence ID" value="EEZ40330"/>
        <property type="gene ID" value="VDA_001355"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0564">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1714699at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140098">
        <property type="term" value="F:catalytic activity, acting on RNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004730">
        <property type="term" value="F:pseudouridylate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034470">
        <property type="term" value="P:ncRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006224">
        <property type="entry name" value="PsdUridine_synth_RluC/D_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01129">
        <property type="entry name" value="PSI_RLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PseudoU_synth_2" evidence="1">
        <location>
            <begin position="25"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="259" mass="29905" checksum="FD485D46DED77722" modified="2010-01-19" version="1">MHDVTLDTPLIPKVELEILYQDEYLVAVNKPSGMLVHRSWLDSHETVFVMQTLRDQIGQHVFPLHRLDRPTSGVLLFALSSEMAAEMMPKFAGRDVHKTYHAVVRGWVKEAAVLDYPLKKELDKIADKNASKEQEAQPAVTAYAPIAKVEVPIAVGRYSCSRYSLVEMKPETGRKHQLRRHMHHLSHHIIGDVNHGDGRHNRMFRDNYDCHRLMLHASRIQFEHPITKQMLDIRAQVDETWLRVMAAFNWDVTLLQPQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWC0</accession>
    <name>D0YWC0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Methionine ABC transporter permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_001383</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297974.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001383"/>
    <dbReference type="EnsemblBacteria" id="EEZ40358">
        <property type="protein sequence ID" value="EEZ40358"/>
        <property type="gene ID" value="VDA_001383"/>
    </dbReference>
    <dbReference type="GeneID" id="57339705"/>
    <dbReference type="eggNOG" id="COG2011">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1464674at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="23"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="93"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="157"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="199"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="24"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="228" mass="23846" checksum="34FB53C555136F16" modified="2010-01-19" version="1">MSLNSISSWFANNERLTALLIEALGQTLVMVLVSGLIGFIIGIPLGVMLHLSKKGGLLENKALNKSLGFIVNIGRSIPFIILLVAIIPFTRFVVGSSIGTAAAIVPLTVGAIPFIARLVEGALLEVPAGLVEAAQAMGATPKQIITKVLLPEALPGIINGVTITLVTLVSYSAMAGTVGGGGLGDVGIRYGYQRFDGTVMAITVVMLIILVQLIQSIGDYCVKRVDHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWG0</accession>
    <name>D0YWG0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Octanoyltransferase</fullName>
            <ecNumber evidence="6 7">2.3.1.181</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Lipoate-protein ligase B</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Lipoyl/octanoyl transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">lipB</name>
        <name evidence="12" type="ORF">VDA_001419</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6 7">Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6 7">
            <text>L-lysyl-[protein] + octanoyl-[ACP] = H(+) + holo-[ACP] + N(6)-octanoyl-L-lysyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17665"/>
            <dbReference type="Rhea" id="RHEA-COMP:9636"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:9928"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78463"/>
            <dbReference type="ChEBI" id="CHEBI:78809"/>
            <dbReference type="EC" id="2.3.1.181"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 6 7">Protein modification; protein lipoylation via endogenous pathway; protein N(6)-(lipoyl)lysine from octanoyl-[acyl-carrier-protein]: step 1/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="6">In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the LipB family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.181" evidence="6 7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001419"/>
    <dbReference type="EnsemblBacteria" id="EEZ40393">
        <property type="protein sequence ID" value="EEZ40393"/>
        <property type="gene ID" value="VDA_001419"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0321">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00538">
        <property type="reaction ID" value="UER00592"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033819">
        <property type="term" value="F:lipoyl(octanoyl) transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009249">
        <property type="term" value="P:protein lipoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16444">
        <property type="entry name" value="LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00013">
        <property type="entry name" value="LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004143">
        <property type="entry name" value="BPL_LPL_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000544">
        <property type="entry name" value="Octanoyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020605">
        <property type="entry name" value="Octanoyltransferase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03099">
        <property type="entry name" value="BPL_LplA_LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016262">
        <property type="entry name" value="LPLase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00214">
        <property type="entry name" value="lipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51733">
        <property type="entry name" value="BPL_LPL_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01313">
        <property type="entry name" value="LIPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="BPL/LPL catalytic" evidence="11">
        <location>
            <begin position="31"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6 9">
        <location>
            <begin position="70"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6 9">
        <location>
            <begin position="137"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6 9">
        <location>
            <begin position="150"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="6 8">
        <location>
            <position position="168"/>
        </location>
    </feature>
    <feature type="site" description="Lowers pKa of active site Cys" evidence="6 10">
        <location>
            <position position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR016262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR016262-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR016262-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR016262-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ40393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="215" mass="23984" checksum="14C8EB6295A59979" modified="2010-01-19" version="1">MQTSLIVRNLGRQDYATTFQAMHTFTNERSSETTDEVWLVEHNPVFTQGQAGKEEHLLNTGDIPVVQSDRGGQVTYHGPGQQVAYVLIDLRRKKLGVRDLVTHIENTIINTLSRFGITAVSRPDAPGVYVNGSKICSLGLRIRRGCSFHGLALNINMDLAPFLRINPCGYAGMNMTQTAQLNGPTTLTEIQPVLVEELTKLLDYQNIEWQTESKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWG4</accession>
    <name>D0YWG4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Endolytic peptidoglycan transglycosylase RlpA</fullName>
            <ecNumber evidence="3">4.2.2.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rlpA</name>
        <name evidence="7" type="ORF">VDA_001423</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the RlpA family.</text>
    </comment>
    <dbReference type="EC" id="4.2.2.-" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298035.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001423"/>
    <dbReference type="EnsemblBacteria" id="EEZ40397">
        <property type="protein sequence ID" value="EEZ40397"/>
        <property type="gene ID" value="VDA_001423"/>
    </dbReference>
    <dbReference type="GeneID" id="57339652"/>
    <dbReference type="eggNOG" id="COG0797">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2027419at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008932">
        <property type="term" value="F:lytic endotransglycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042834">
        <property type="term" value="F:peptidoglycan binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000270">
        <property type="term" value="P:peptidoglycan metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02071">
        <property type="entry name" value="RlpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034718">
        <property type="entry name" value="RlpA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009009">
        <property type="entry name" value="RlpA-like_DPBB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012997">
        <property type="entry name" value="RplA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007730">
        <property type="entry name" value="SPOR-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036680">
        <property type="entry name" value="SPOR-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03330">
        <property type="entry name" value="DPBB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05036">
        <property type="entry name" value="SPOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110997">
        <property type="entry name" value="SSF110997"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="SSF50685"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00413">
        <property type="entry name" value="rlpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51724">
        <property type="entry name" value="SPOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="1 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5009991133" description="Endolytic peptidoglycan transglycosylase RlpA" evidence="3">
        <location>
            <begin position="19"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="SPOR" evidence="6">
        <location>
            <begin position="209"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="18"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="24"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="289" mass="32355" checksum="31C41BC0A4FCFB5F" modified="2010-01-19" version="1" precursor="true">MRSIFLIFLLILAGCSSSPETTEQSKADKPEVTQPPKKHDPDNMDPNAGRYSLEHDKAPDVIPVLKNIKDAVPRYEPRSLAGNKDYTLRGKRYHIIKNPKGFTQTGYASWYGMKFHGHKTANGETYDIYDMTAAHKTLPIPSYVKVTNTRNGKTAIVRVNDRGPFHDGRIIDLSLAAATKLDVVNHGTAPVKIEVISVPKPTTVQGWHAVTPHYYYVQLAAVAGESKAEEMKASLRKKYGVPVNTQRVNTSTTYRVRLGPYLDHDAAQHMLDRVKVNQYPKAFITTVNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWI1</accession>
    <name>D0YWI1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 14">Adenine DNA glycosylase</fullName>
            <ecNumber evidence="4 14">3.2.2.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">VDA_001223</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>Hydrolyzes free adenine bases from 7,8-dihydro-8-oxoguanine:adenine mismatched double-stranded DNA, leaving an apurinic site.</text>
            <dbReference type="EC" id="3.2.2.31"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="14">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the Nth/MutY family.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.31" evidence="4 14"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297671.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001223"/>
    <dbReference type="EnsemblBacteria" id="EEZ40201">
        <property type="protein sequence ID" value="EEZ40201"/>
        <property type="gene ID" value="VDA_001223"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1194">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1274533at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000701">
        <property type="term" value="F:purine-specific mismatch base pair DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03431">
        <property type="entry name" value="DNA_Glycosylase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005760">
        <property type="entry name" value="A/G_AdeGlyc_MutY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004036">
        <property type="entry name" value="Endonuclease-III-like_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003651">
        <property type="entry name" value="Endonuclease3_FeS-loop_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004035">
        <property type="entry name" value="Endouclease-III_FeS-bd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023170">
        <property type="entry name" value="HhH_base_excis_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000445">
        <property type="entry name" value="HhH_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044298">
        <property type="entry name" value="MIG/MutY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029119">
        <property type="entry name" value="MutY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42944">
        <property type="entry name" value="PTHR42944"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10576">
        <property type="entry name" value="EndIII_4Fe-2S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00633">
        <property type="entry name" value="HHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14815">
        <property type="entry name" value="NUDIX_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00525">
        <property type="entry name" value="FES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="SSF48150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01084">
        <property type="entry name" value="mutY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00764">
        <property type="entry name" value="ENDONUCLEASE_III_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01155">
        <property type="entry name" value="ENDONUCLEASE_III_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="8 14" id="KW-0227">DNA damage</keyword>
    <keyword evidence="12" id="KW-0234">DNA repair</keyword>
    <keyword evidence="13 14" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 14" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ENDO3c" evidence="15">
        <location>
            <begin position="38"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU365096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EEZ40201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="356" mass="40459" checksum="940508E8742F8753" modified="2010-01-19" version="1">MSHNFSTAILTWYDKFGRKTLPWQQNKTPYKVWLSEIMLQQTQVATVIPYFERFMAQFPTVQDLAQAPQDEVLHLWTGLGYYARARNLHKAAQVIVEQYNGIFPTDIDQVQALPGIGRSTAGAVLSLSLKQHHPILDGNVKRTLSRCYGIEGWPGQKAVENKLWQIAEQNTPSDGVERYNQAMMDMGAMICTRSKPKCELCPVADMCVAKAQGRQTDFPGKKPKTTKPEKQAWFAIIQCGDEVWLEQRPQSGIWGGLWCFPQQDHEDLTPLIESRLGMTLAQLDADGMVKKEQLTAFRHTFSHYHLDIIPVLFTIQHQPNLIRENGQWYSLTHPAKVGLAAPVQKILDSLSYDLPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWJ0</accession>
    <name>D0YWJ0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Type IV pilus (Tfp) assembly protein ATPase component PilU</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001232</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GSP E family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297691.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001232"/>
    <dbReference type="EnsemblBacteria" id="EEZ40210">
        <property type="protein sequence ID" value="EEZ40210"/>
        <property type="gene ID" value="VDA_001232"/>
    </dbReference>
    <dbReference type="GeneID" id="57339890"/>
    <dbReference type="eggNOG" id="COG5008">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="473670at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01131">
        <property type="entry name" value="PilT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006321">
        <property type="entry name" value="PilT/PilU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001482">
        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00437">
        <property type="entry name" value="T2SSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01420">
        <property type="entry name" value="pilT_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T2SP_E" evidence="2">
        <location>
            <begin position="112"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="368" mass="41355" checksum="BA9DFA622F80A631" modified="2010-01-19" version="1">MKLQEILNQVVERKASDLYITVDSPCLLKVDGVLHPIGDTLDRTGVDLLFDEAMDSALYQEFVDTREANFALVRGDWRFRVSAFWQRELPGMVVRRIETDIPDIFSLKLPMDMQKMALAKRGLVLVVGATGSGKSTSMAAMTGFRNQNRSGHILTVEDPIEFVHKHDKCIVTQREVGLDTESYEVALKNSLRQAPDMILIGEIRTQETMEYAMNFAETGHLCMATLHANNANQALERILHLVPKERQHQFLFDLSLNLKCILAQQLIPDAHGQGRHAAFELLINTPRVADLIRRGELYEIKDVMAKSGESGMMTFDQSLYELFTKGAITEQDALHHADSPNDLRLMIKVGSKDKTAINALDGVTVDFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWP4</accession>
    <name>D0YWP4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">3-oxoacyl-[acyl-carrier-protein] synthase KASI</fullName>
            <ecNumber evidence="5">2.3.1.41</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001530</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.41" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298224.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001530"/>
    <dbReference type="EnsemblBacteria" id="EEZ40504">
        <property type="protein sequence ID" value="EEZ40504"/>
        <property type="gene ID" value="VDA_001530"/>
    </dbReference>
    <dbReference type="GeneID" id="57342413"/>
    <dbReference type="eggNOG" id="COG0304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="572620at2"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00834">
        <property type="entry name" value="KAS_I_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000794">
        <property type="entry name" value="Beta-ketoacyl_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11712">
        <property type="entry name" value="PTHR11712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="B_KETOACYL_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PKS_KS" evidence="4">
        <location>
            <begin position="4"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="404" mass="42853" checksum="4EFE96E4CFEDFCC1" modified="2010-01-19" version="1">MKRAVITGMGIISSIGNNVEEVLESLKAGKSGINFSEQFAEMKLRSQVWGDLKINPAEHIDRKQMRFMGNAAAYAFLSMEQAIADSGLTEDQVSNERTGLVAGSGGASSMNQVAAVDILREKGVKRVGPYMVPRTMSSTVSACLATPFKIRGVNYTMSSACATSAHCIGHAVELIQLGKQDVVFAGGGEELDWSLTMMFDAMGALSTKYNDDPSKASRTYDADRDGFVISGGGGMVVIEELEHALARGAKIYGEVVGYGATSDGYDMVAPSGEGAVRCMKMAMQDLDAPVDYINTHGTSTPVGDVKELGAIQELFSENCPAISATKAMTGHALGAAGVHEAIYSTLMLDNNFVAPSINIENLDEAAQGLDIVTEMREQELKTVMSNSFGFGGTNATLVIKKFEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWQ5</accession>
    <name>D0YWQ5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Methyl-accepting chemotaxis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">VDA_001451</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the methyl-accepting chemotaxis (MCP) protein family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298081.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001451"/>
    <dbReference type="EnsemblBacteria" id="EEZ40425">
        <property type="protein sequence ID" value="EEZ40425"/>
        <property type="gene ID" value="VDA_001451"/>
    </dbReference>
    <dbReference type="GeneID" id="57339594"/>
    <dbReference type="eggNOG" id="COG0840">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="477199at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033479">
        <property type="entry name" value="dCache_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029151">
        <property type="entry name" value="Sensor-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02743">
        <property type="entry name" value="dCache_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103190">
        <property type="entry name" value="SSF103190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0807">Transducer</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="276"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="11">
        <location>
            <begin position="296"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="10">
        <location>
            <begin position="355"/>
            <end position="591"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ40425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="627" mass="68058" checksum="EBE806414E26C212" modified="2010-01-19" version="1">MKLTLKQKLIGSSLIALILMATSLTWLAANRLSEQTQQGIHSRVESLTNAATSGIRDWIQIRKSIASAFNHFATAPDVVPYLQQARYAGGFDDIYFGTPEGKMYRSHPERNRADYDPRTRPWYQSAESENKQLITPAYRDAITNALLVTIAEPVHHNGQMLGIVGADVLIDQLINDVISLDAGKNASAMLIDRNNGTFLANSNQDLLLKPISALSSQLSINSVEQQINHQQFETITIDGQPKLLYFTNVPNTPWIFGVELDQATEEASYYASLTQLLITSVIITLAVIIAVTLLVNYLFRDLARVSQALAEIANGEGDLTQRLEPHSEDEVGQLAHNFNRFVGNMHGMVSRLNDVSSALTQQAHITASQAEERSSRIQHQQDEINMVATAINEMAAATQEIAGNADNTAQTAGETVEVSDHGSTQVGQSQQSISSLASEVETATVVIEELNSHAQSINSILATIQGIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRVLSQRTHASTQEIQQTIETLQQTTGKAVGIMEDSRRLAEASVDDANSASASLNQITAAVTNISDMATQIASAAEEQSSVTSEITRNTEGIRDVSNELATEAHEAAKQAADLSQLSFELQQEINRFKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWQ8</accession>
    <name>D0YWQ8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001454</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001454"/>
    <dbReference type="EnsemblBacteria" id="EEZ40428">
        <property type="protein sequence ID" value="EEZ40428"/>
        <property type="gene ID" value="VDA_001454"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2606">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.960.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036754">
        <property type="entry name" value="YbaK/aa-tRNA-synt-asso_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007214">
        <property type="entry name" value="YbaK/aa-tRNA-synth-assoc-dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04073">
        <property type="entry name" value="tRNA_edit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55826">
        <property type="entry name" value="SSF55826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA_edit" evidence="1">
        <location>
            <begin position="2"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="101" mass="10446" checksum="ACC7B9AE8F3C4EA1" modified="2010-01-19" version="1">MAVAVVPVSGMLDLKAAAKAAGGKKAEMADPKLAEKVTGYIVGGISPLGQKKRLPTFVDAGAEQFETIFVSAGRRGLDIELTAKDLVSLTNGKFAPIGKMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWR6</accession>
    <name>D0YWR6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hypothetical oxidoreductase short-chain dehydrogenase/reductase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001462</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298103.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001462"/>
    <dbReference type="EnsemblBacteria" id="EEZ40436">
        <property type="protein sequence ID" value="EEZ40436"/>
        <property type="gene ID" value="VDA_001462"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1582456at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="274" mass="31001" checksum="178F0E82EF10E04E" modified="2010-01-19" version="1">MLSILITGCSSGIGFYCAKQLHQAGHHVVATCRTEHDHKTLQQLGISTVNMEMSDDISIEKGFAQALTLLNGKIDILFNNAAYGQPGALEDLPTEALKEQFATNFFGWHTLTRLTIRQMLKQKSGKIVQNSSVLGLVAMKYRGAYNASKFAIEGYTDTLRLELADTPIHISLIEPGPIESQFRATAKRYFERYINIEHSRHKLSYQQTLERLGNPSPSNRFTLQPDAVYQRLLSIIEAKQPKARYFVTQPTYIFAFLRRVLPNRLLDKIVSKSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-06-02" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWS7</accession>
    <name>D0YWS7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_001472</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298123.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001472"/>
    <dbReference type="EnsemblBacteria" id="EEZ40446">
        <property type="protein sequence ID" value="EEZ40446"/>
        <property type="gene ID" value="VDA_001472"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4191">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4192">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024478">
        <property type="entry name" value="HlyB_4HB_MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017116">
        <property type="entry name" value="Sig_transdc_His_kinase_PgtB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12729">
        <property type="entry name" value="4HB_MCP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037119">
        <property type="entry name" value="STHK_PgtB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="325"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="9">
        <location>
            <begin position="348"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="8">
        <location>
            <begin position="574"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="538"/>
            <end position="565"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ40446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="789" mass="89194" checksum="2D9966E780BEF11D" modified="2010-01-19" version="1">MSVRRSNKTIGNRLISAIGFMAFLTIMVSLIAATNWERLNRQIETIVHQNMPTLQVSYQLERKPAGLQSGLSEIELTQDPIVFTALKNEINQHLESITAAIKKTISLQNHVTLKQEHELLTQDIAVYINLLAQRNDVLTNLKQTQNAIKWLHQDLIDELSPLRQDVEWQLKRMMPAVQQDRALAEVMTEFSLIQAITIKENELHQLIEDIILQRRQRDLGNAFYFIDYKIKEITRLSLQLAHYQTTTNYRQLLKEFITLTSPQGDLQKQLRQDVELSKKITQLQRSIGRQMTHQEELIQTMVTQADNDLNHLNKETRHTITLSNIILFGVVFLTIFVSIILSIYLVGKGIVKRLNLLSQDLRAVTDGKLDSPIQVSGDDEIGLIGNNLRLFCQQMQEMQKTNALSLINNTQASIITCNLSGTIESMNPSAQKLFQLGNNDSLVQIWGLFKHDMHGRLQALFDASSPLLSQGACNLTICQKISDETTYLRLDFRIFQQGNQDKVIVTITDITEQENIARWLESMVKEKTLSLTNRNRQLKAEIEDRKRIEADLRNTQDELIQAAKMAVVGQTMTSLAHELNQPLSAISTHIFTAKMAIERENYTKLLTTIDKVDNLTSRMGRIISSLKSFSKKQSAGNALVNVDVQESISQAMMIVESRAKMQQTVINNLVPSGLFAFADQVQLEQVLVNLLVNSCDAVARNQHRSIDIILLSQDSESIKLAVSDSGSGFGEDIIKKLFIPFTTTKDVGLGLGLSICRSIMTRLNGDIFLASNLNHGAMVVLELKHYVNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWT2</accession>
    <name>D0YWT2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Pyruvate formate-lyase activating enzyme</fullName>
            <ecNumber evidence="9">1.97.1.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_001477</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="1.97.1.4" evidence="9"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001477"/>
    <dbReference type="EnsemblBacteria" id="EEZ40451">
        <property type="protein sequence ID" value="EEZ40451"/>
        <property type="gene ID" value="VDA_001477"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1180">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043365">
        <property type="term" value="F:[formate-C-acetyltransferase]-activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034457">
        <property type="entry name" value="Organic_radical-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012838">
        <property type="entry name" value="PFL1_activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30352">
        <property type="entry name" value="PTHR30352"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02493">
        <property type="entry name" value="PFLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="8">
        <location>
            <begin position="1"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ40451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="182" mass="20958" checksum="043B260C338F8E81" modified="2010-01-19" version="1">MNSSGGGVTASGGEAMLQPEFVRDFFRAAHAEGIHTCLDTNGYIRKHTDVVDEVLDDTDLVMLDLKQLDDSIHRELVGVPNKRVLDFAHYLHQRGQKTWIRYVIVPGYTDDERSAHLLGEFIQDMDNIEKVELLPYHQLGEHKWEAMGFDYPLKGVKPPKKETMEKIKEIIQSYNPERKVMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWW9</accession>
    <name>D0YWW9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">30S ribosomal protein S1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_001802</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bS1 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298730.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001802"/>
    <dbReference type="EnsemblBacteria" id="EEZ40770">
        <property type="protein sequence ID" value="EEZ40770"/>
        <property type="gene ID" value="VDA_001802"/>
    </dbReference>
    <dbReference type="GeneID" id="57342083"/>
    <dbReference type="eggNOG" id="COG0539">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1235756at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035104">
        <property type="entry name" value="Ribosomal_protein_S1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000110">
        <property type="entry name" value="Ribosomal_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10724:SF7">
        <property type="entry name" value="PTHR10724:SF7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002111">
        <property type="entry name" value="RpsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00681">
        <property type="entry name" value="RIBOSOMALS1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00717">
        <property type="entry name" value="rpsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="S1 motif" evidence="5">
        <location>
            <begin position="21"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="5">
        <location>
            <begin position="105"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="5">
        <location>
            <begin position="192"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="5">
        <location>
            <begin position="277"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="5">
        <location>
            <begin position="364"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="5">
        <location>
            <begin position="451"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR002111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="556" mass="60612" checksum="BFC3E7D201E3BEEF" modified="2010-01-19" version="1">MTESFASLFEESLKELETRPGQIVKGTVVAIENGYVLVDAGLKSESSIPAEQFKNAAGELEIEVGSEVDVAIDAIEDGFGETQLSREKAKRHEAWIQLEKAYEDAETVVGIINGKVKGGFTVELNGIRAFLPGSLVDVRPVRDTAHLENKELEFKVIKLDQKRNNVVVSRRAVIESENSVERDELLASLQEGMEVKGIVKNLTDYGAFVDLGGVDGLLHITDMAWKRVKHPSEIVNVGDEINVKVLKFDRDRTRVSLGLKQLGEDPWVAIAKRYPEGTKLTGRVTNLTDYGCFVEIEEGVEGLVHVSEMDWTNKNIHPSKVVNVGDEVEVMVLDIDEERRRISLGLKQCKANPWQSFAEMQAKGDKVTGKIKSITDFGIFIGLEGGIDGLVHLSDISWNVAGEEAVRDFKKGDEISAVVLAVDAERERISLGIKQIEEDPFNGFVAATKKGALVNGTVTAVDAKGATVELAEGVEGYLRASEASVDRVEDATLVLSVGDSVEAKFTGVDRKNRVINLSVRAKDVAEEQEAMAALNKQDDAAFGNAMADAFKAAKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWX3</accession>
    <name>D0YWX3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Orotidine 5'-phosphate decarboxylase</fullName>
            <ecNumber evidence="7">4.1.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">OMP decarboxylase</fullName>
            <shortName evidence="7">OMPDCase</shortName>
            <shortName evidence="7">OMPdecase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pyrF</name>
        <name evidence="10" type="ORF">VDA_001806</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7 8">
            <text>H(+) + orotidine 5'-phosphate = CO2 + UMP</text>
            <dbReference type="Rhea" id="RHEA:11596"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57538"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="EC" id="4.1.1.23"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 7 8">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the OMP decarboxylase family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.23" evidence="7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298737.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001806"/>
    <dbReference type="EnsemblBacteria" id="EEZ40774">
        <property type="protein sequence ID" value="EEZ40774"/>
        <property type="gene ID" value="VDA_001806"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0284">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1150446at2"/>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004590">
        <property type="term" value="F:orotidine-5'-phosphate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01200_B">
        <property type="entry name" value="OMPdecase_type1_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014732">
        <property type="entry name" value="OMPdecase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018089">
        <property type="entry name" value="OMPdecase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001754">
        <property type="entry name" value="OMPdeCOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32119:SF2">
        <property type="entry name" value="PTHR32119:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00215">
        <property type="entry name" value="OMPdecase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00934">
        <property type="entry name" value="OMPdecase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01740">
        <property type="entry name" value="pyrF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00156">
        <property type="entry name" value="OMPDECASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 8" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="6 7 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 7 8" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OMPdecase" evidence="9">
        <location>
            <begin position="10"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="65"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="67"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="16"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="215"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="216"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ40774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="239" mass="25700" checksum="FB2E8C9F141C7369" modified="2010-01-19" version="1">MLDTQLMDPKVIVALDYDNQNDALAFVDRIEPGSCRLKVGKEMFTFYGPDFVRKLHDRGHSVFLDLKFHDIPNTCSKAVKAAAELGVWMVNVHASGGERMMTASREILEPYGKDRPLLIGVTVLTSMESSDLSGIGISRSPQEQVMNLATLTKNSGLDGVVCSAQEASLLKSNLGQEFKLVTPGIRPAGSAAGDQRRVMTPVEAIAAGSDYLVIGRPITQAENPAQVLADINATLAGVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWZ4</accession>
    <name>D0YWZ4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002047</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41015">
        <property type="protein sequence ID" value="EEZ41015"/>
        <property type="gene ID" value="VDA_002047"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031NY5">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="7"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="90" mass="10346" checksum="33A189867DECE37C" modified="2010-01-19" version="1">MSNRIQQTKLISANQSLQQTITQLEQQALQEQQAAKQAEQARQVWQQRAEQAKQQIEKDISHEECADLPIPNAAHWMYYDTATGDHSVQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX08</accession>
    <name>D0YX08_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002065</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299326.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41033">
        <property type="protein sequence ID" value="EEZ41033"/>
        <property type="gene ID" value="VDA_002065"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="68" mass="7468" checksum="C428BF9C2C4B9C44" modified="2010-01-19" version="1">MSNNTQPKATNFIEQGMKEAIKNYLDGAEDTNKSFAKVAGSELKKGNGATMAQYNSNKRNIDKAKNEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX31</accession>
    <name>D0YX31_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hypothetical transcriptional regulator TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001905</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298909.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001905"/>
    <dbReference type="EnsemblBacteria" id="EEZ40873">
        <property type="protein sequence ID" value="EEZ40873"/>
        <property type="gene ID" value="VDA_001905"/>
    </dbReference>
    <dbReference type="GeneID" id="57341970"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039536">
        <property type="entry name" value="TetR_C_Proteobacteria"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14246">
        <property type="entry name" value="TetR_C_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="12"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="209" mass="23808" checksum="0C6D290F720109A8" modified="2010-01-19" version="1">MSTKKVLTPRSQRKREQILAAASELFMSQGYMTSMDLIAEQAGVSKQTVYSHFKTKDDLFDTCIRAKCVAAEFTETALDHSLPIREFLCQFAYRFQAMLLSTEAVLMFRTAISQIDNHPDLAKTYLAAGPEATVILLVQFLELKQQQGIIAIPENMTLEQAAMQLLLMWHGKAVYWRYLGQETQELETELHHYLDACVDLFLAGYQVDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX76</accession>
    <name>D0YX76_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phospho-2-dehydro-3-deoxyheptonate aldolase</fullName>
            <ecNumber evidence="5">2.5.1.54</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_001935</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 5">Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14717"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16897"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="2.5.1.54"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 5">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 1/7.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the class-I DAHP synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.54" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298965.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001935"/>
    <dbReference type="EnsemblBacteria" id="EEZ40903">
        <property type="protein sequence ID" value="EEZ40903"/>
        <property type="gene ID" value="VDA_001935"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0722">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="853329at2"/>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00084"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003849">
        <property type="term" value="F:3-deoxy-7-phosphoheptulonate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006218">
        <property type="entry name" value="DAHP1/KDSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006219">
        <property type="entry name" value="DHAP_synth_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21225">
        <property type="entry name" value="PTHR21225"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00793">
        <property type="entry name" value="DAHP_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001361">
        <property type="entry name" value="DAHP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00034">
        <property type="entry name" value="aroFGH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAHP_synth_1" evidence="6">
        <location>
            <begin position="44"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR001361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="352" mass="38391" checksum="82F26EEFF4045E0A" modified="2010-01-19" version="1">MPMKTDELRTVSLGVMPTPAEIEAASPTTDEIALHVARSRQQVEAILSGQDSRLLVIVGPCSIHDPEAAIDYAKRLHALQEKYRDQLFIVMRTYFEKPRTVVGWKGLVSDPHLDGSLDLVAGLHKARKLLVDVNALGMPTATEFLDMVTGQYLADLITWGAIGARTTESQIHREMASGLSCPVGFKNGTDGNIQIAIDAIRATRAPHVFCSPDKHGQMTIYRTSGNPYGHIILRGGKAPNYGEHDVTLSCQTLAQFDLPQRLVIDFSHGNCQKQHKRQLDVAADICQQIQSGSRAIAGIMAESFIVEGNQAVIAGKENELQYGCSITDPCLGWDDTATMIEMLADAVKATQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX99</accession>
    <name>D0YX99_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ABC-type antimicrobial peptide transport system permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_001958</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299017.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001958"/>
    <dbReference type="EnsemblBacteria" id="EEZ40926">
        <property type="protein sequence ID" value="EEZ40926"/>
        <property type="gene ID" value="VDA_001958"/>
    </dbReference>
    <dbReference type="GeneID" id="57341903"/>
    <dbReference type="eggNOG" id="COG0577">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="856767at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038766">
        <property type="entry name" value="Membrane_comp_ABC_pdt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30287">
        <property type="entry name" value="PTHR30287"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="241"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="342"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="389"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="414"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="462"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="688"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="734"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="785"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="8">
        <location>
            <begin position="719"/>
            <end position="811"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ40926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="821" mass="91466" checksum="848697EA6291C91B" modified="2010-01-19" version="1">MLSPVIKALWGHYKRHPFQIMLVWLGLTLGIALLVGVMGVNQQARESYRQGELLFSNPYPYRIRTAQLGLKVPQGFYIQLRRAGLKSCAPLDSYRIVTEQGRDFELVGLDPVAMFSAFTRSEKNMATLRADMLDLMKPPYPIIAGEQLASYMGVKSGDMITLDSGKKIGPVEIVPDELTGGPRLVADIARLRDIQPSSGFTSIVCGEMSHEQLVRLTQILPPGLTLQRNQSARLEPLTNAFHLNLFAMGMLSFVVGLFIFYQAMSLSFTQRQPLVGRLTQLGVTGLQLAAALSIELILWIILGLIGGNLLGLVLAQQLMPSVAATLSDLYGANVNLAVSWHWQWGVASLIIAGCGSILACGWPMVRLIKTPPVRLATHMALVRFSGREFAWQSIISLIFILVAIGIYQLPHGQFAGFVLIALILTASGLLMPYLLWKSFQILGVIFPSVKMRWFFTDAASSLSYRGVAAMAFMLALASNIGMETMVGSFRHTTHTWLEQRLAADIYIRPSMNMAPRMYRWLEDQPEVNDVWWRWQKETPTDAGTLQVMSIGQSEGEMTALSVKDIEPNYWQSLHSQRAVMVSESLALKNNWHIGDMVDLPTPMNDNWRIVGIYYDYGNPYGQLLISYNKWHRYWPHSGQVGLAIHLNPGANDEALLAKLGERFRLQPERIRNNSDLMTQAMRVFDQTFVVTSTLGSLTLFIAVCGLFFATLAGEVSRQRQFALLRCMGMTGLELAVLGGGQLLLIGLFTALMALPLGLILAQLLIDVVLKYSFGWTMPIHYFPTQYLFTLGSALVVLLIAGGWPVWRLVKRSAILSLREAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXC9</accession>
    <name>D0YXC9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001669</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001669"/>
    <dbReference type="EnsemblBacteria" id="EEZ40642">
        <property type="protein sequence ID" value="EEZ40642"/>
        <property type="gene ID" value="VDA_001669"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1295">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005274">
        <property type="entry name" value="IM_pro_YhjD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017039">
        <property type="entry name" value="Virul_fac_BrkB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30213">
        <property type="entry name" value="PTHR30213"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03631">
        <property type="entry name" value="Virul_fac_BrkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF035875">
        <property type="entry name" value="RNase_BN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00766">
        <property type="entry name" value="TIGR00766"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="69"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="183"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="225"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="259"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="293"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="324"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="347" mass="37897" checksum="E81EA514FB8ED60C" modified="2010-01-19" version="1">MALKFQFIQTILSIMTNEVSEKTSSTVVQKITAAAMWLLEKIKALPPIAHFIRAADRFNDRLGSQFGAAITYFSFLSLIPILMVLFAAAGFILASNADLLTDIIDKIVNGVTDPSLAQTLKNTVNTAVNQRTTVGLSGLAIALYSGISWMGNLREAVRAQTRDIWERKPEDKDHILLQYGKDFIALTGLVAALIFTVALTSIAGSAQASIVNALGLNDVTWLRPVLTTIALTISISANYLMFLWIYWMLPKKKLERKALILGTLMAAIGFEGIKFAMTFMLPKLAQSPSGAAFGSIIGLMAFFYFFARLTLFCAAWIATAEPSKKKHLDGAEQTEAPEVEEQTSASN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXF9</accession>
    <name>D0YXF9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">EAL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001638</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298422.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001638"/>
    <dbReference type="EnsemblBacteria" id="EEZ40611">
        <property type="protein sequence ID" value="EEZ40611"/>
        <property type="gene ID" value="VDA_001638"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2200">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="2">
        <location>
            <begin position="60"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="311" mass="35192" checksum="9A35DAB4E44F10D2" modified="2010-01-19" version="1">MAKVHKLTFLNVAILVTICISIFIEVLDINHQGLSLAVYAILAVNLLTSLFLYYKLTPTSILLKYQLLNAVKKNELLPYYQPIIDSKNNTTCGYEVLIRWKKPDNKIIEPLDFIPESEQNGLITPITFQLISQVAKDIKSLQELNQGFSINRYFSINVSATTLEDDELVRYIKAVLEEYNIPGQYFALELTERTPIKNLENASRVCQELNAIGIKIKIDDIGMGYNDVTILQKLCATTIKVDKSFIDKIDKVEQKNLLECLVIFADRAEVEIIAEGIEDKSQAETLNSIGIHYHQGFLYGKPQPITSINMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXG3</accession>
    <name>D0YXG3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001698</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298535.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40669">
        <property type="protein sequence ID" value="EEZ40669"/>
        <property type="gene ID" value="VDA_001698"/>
    </dbReference>
    <dbReference type="GeneID" id="57342220"/>
    <dbReference type="eggNOG" id="COG2431">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1614756at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015661">
        <property type="term" value="F:L-lysine efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005642">
        <property type="entry name" value="LysO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35804">
        <property type="entry name" value="PTHR35804"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03956">
        <property type="entry name" value="Lys_export"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="202"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="233"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="275"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="299" mass="32472" checksum="DA2029EC773BA7BC" modified="2010-01-19" version="1">MFSGMLFIFLPLIIGYLIPIKNASLLNHVNVLTSRLVLVILALMGLSLANLDNLSQNLEQILLYAGTFFVAISFCNLVALPFLDIRWNLATEKKQKSMPLMKMLFESFQLIFVVGGGLIIGLLINMNLSWVDKASEIILFILLFFIGIQLRNSGMTLRQILLNKKGMILASVILTTSLLGGVIAALILDIPIKNGLAMASGFGWYSLAGILMGDGLGPIYGGAAFLNELMRELVALTLIPMIINQRPAMAIGYAGATAMDFTLPVIQNCGGIRCVPIAIVSGFILSMLVPVLMLFFISL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXH8</accession>
    <name>D0YXH8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Malonyl CoA-acyl carrier protein transacylase</fullName>
            <ecNumber evidence="2 5">2.3.1.39</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_001685</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>holo-[ACP] + malonyl-CoA = CoA + malonyl-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:41792"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="EC" id="2.3.1.39"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the fabD family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.39" evidence="2 5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298512.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001685"/>
    <dbReference type="EnsemblBacteria" id="EEZ40656">
        <property type="protein sequence ID" value="EEZ40656"/>
        <property type="gene ID" value="VDA_001685"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0331">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1123553at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004314">
        <property type="term" value="F:[acyl-carrier-protein] S-malonyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024925">
        <property type="entry name" value="Malonyl_CoA-ACP_transAc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004410">
        <property type="entry name" value="Malonyl_CoA-ACP_transAc_FabD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000446">
        <property type="entry name" value="Mct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="SSF55048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00128">
        <property type="entry name" value="fabD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PKS_AT" evidence="7">
        <location>
            <begin position="7"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="92"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR000446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000446-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ40656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="309" mass="32437" checksum="3C609E5689880569" modified="2010-01-19" version="1">MSKFAIVFPGQGSQAVGMLAELAEQFPIVQATFAEASEVLGYDLWALVQNGPAEDLNQTHRTQPALLTASVAIWRVWQEKGGEQPTVLAGHSLGEYSALVCAGVIDFKEAVKLVELRGQLMQEAVPAGVGAMSAIIGLDNDAIAKACADAAEDQVCSPVNFNSPGQVVIAGNKEAVDRANTLCKEAGAKRALLLPVSVPSHCELMKPAADKLAVALENMTFNTPAIPVINNADVATETDPAAIKLALVKQLYGPVRWTESVERMAAEGIEELLEMGPGKVLTGLTKRINRSLGGSAVNDIASLDAALAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXK3</accession>
    <name>D0YXK3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cytochrome c-type protein torC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001717</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001717"/>
    <dbReference type="EnsemblBacteria" id="EEZ40688">
        <property type="protein sequence ID" value="EEZ40688"/>
        <property type="gene ID" value="VDA_001717"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3005">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3820.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018588">
        <property type="entry name" value="Dihaem_cytochrome-c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036280">
        <property type="entry name" value="Multihaem_cyt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005126">
        <property type="entry name" value="NapC/NirT_cyt_c_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038266">
        <property type="entry name" value="NapC/NirT_cytc_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03264">
        <property type="entry name" value="Cytochrom_NNT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09626">
        <property type="entry name" value="DHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48695">
        <property type="entry name" value="SSF48695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Cytochrom_NNT" evidence="3">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="299" mass="32880" checksum="068BCA20EFB86D0A" modified="2010-01-19" version="1">MKAKMGGLGDIYSEFVSKDIDTPAKFEANRLRMAEDVWKMMKATNSAPCKSCHAYSAMDHAKQSPAAAAAMTPAAAKDMNCIECHKGIVHQLPHMKNGFQAEFTQLSASAETAPRANNLYAITSKQLFAAKGSSSAQGQLFPASEVKVLDRQGDELQIQISGWAQQGPTANMLMQEMGKKIVVAALEPELQKTQKVIATETAKDGAKWDHVEVTAWIAQKGMIATLKPLWTYAENMYQDSCSQCHAAPKPSHLTANEWIGSLNSMRQYFILNKNEERVLLKYLQLHAKDSEQAAQTATK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXT8</accession>
    <name>D0YXT8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002101</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299435.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002101"/>
    <dbReference type="EnsemblBacteria" id="EEZ41069">
        <property type="protein sequence ID" value="EEZ41069"/>
        <property type="gene ID" value="VDA_002101"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2836">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1818448at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039447">
        <property type="entry name" value="UreH-like_TM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13386">
        <property type="entry name" value="DsbD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="200"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="DsbD_2" evidence="2">
        <location>
            <begin position="7"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="225" mass="24384" checksum="5C09632BDB7868B5" modified="2010-01-19" version="1">MELDFIAAFMIGLLGSGHCIGMCGGMGAAITLSIDRTDHQRRYLYLLLYNFGRIASYCLLGGVIGALVTGVTSFGSSNSMLIALRLCASMMMILLACYIGGWWFGLTFLEKQGQKIWRYIAPITGRLLPLKSPIYALPLGFLWGWLPCGLVYSALTWAAVSGSALNGSSIMLAFGLGTLPALLLVGFMADTVKSVLKNRYIKHASALLLLFYGIQTGYIAIKQLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXW3</accession>
    <name>D0YXW3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Iron-sulfur cluster-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_002126</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299500.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002126"/>
    <dbReference type="EnsemblBacteria" id="EEZ41094">
        <property type="protein sequence ID" value="EEZ41094"/>
        <property type="gene ID" value="VDA_002126"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1145">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1619561at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00037">
        <property type="entry name" value="Fer4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12838">
        <property type="entry name" value="Fer4_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="178"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="209"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="411"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="442"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="552" mass="60325" checksum="CE34B6E6607B9C4B" modified="2010-01-19" version="1">MLKSTLEAFSDNNGQARLAAITGTVELANLIPPTVTYESRGDLLIVGPQETITPLAAQFAELHSVTLLATEKTSEATEENLYFSDEIHVKGYLGAFEVTCRVSVAGLEPTTNLAKIALGRDSFDLIVDLTENGVMSYEIPAPGYYAIGARKDKLARVIEELPDMLGTFDKPKYFRFNPDLCAHASRGVEGCDRCLDACPAGAISANADQEIEINPYLCQGVGTCATACPTEAITYALPDADDTQHFVHRLLTRYANEGGVKPTLLFYGNRDEANVVNALAHLPTSVIPVALEELATVGVDTWFSALFYGAHQVLLATNTAYIPATIDRVLSDELTTAQMFLTEMGYEADRICLFNFADVENYVPFSEALLPAGEQLSGNKRQKLFTTLEALYAQAPTKPEHSAVIEKAPYGSISCQADDCTLCMGCVAVCPTRALHAIGDRPGLLFIEEDCIQCGMCQKACPENVITVEPGFNWGWQARKEAKLVHEEPAACCINCGKPFAPESMVKMLIEKLQGHSHFQGDAIRRLSMCEDCRVRDIFSKFEDDPEDQIRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYE7</accession>
    <name>D0YYE7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Thiamine-phosphate synthase</fullName>
            <shortName evidence="8">TP synthase</shortName>
            <shortName evidence="8">TPS</shortName>
            <ecNumber evidence="8">2.5.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Thiamine-phosphate pyrophosphorylase</fullName>
            <shortName evidence="8">TMP pyrophosphorylase</shortName>
            <shortName evidence="8">TMP-PPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">thiE</name>
        <name evidence="12" type="ORF">VDA_002310</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8 9">
            <text>2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 2 H(+) = CO2 + diphosphate + thiamine phosphate</text>
            <dbReference type="Rhea" id="RHEA:47848"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:62890"/>
            <dbReference type="EC" id="2.5.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 8 9">
            <text>2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 2 H(+) = CO2 + diphosphate + thiamine phosphate</text>
            <dbReference type="Rhea" id="RHEA:47844"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:62899"/>
            <dbReference type="EC" id="2.5.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 8 9">
            <text>4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 4-methyl-5-(2-phosphooxyethyl)-thiazole + H(+) = diphosphate + thiamine phosphate</text>
            <dbReference type="Rhea" id="RHEA:22328"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:58296"/>
            <dbReference type="EC" id="2.5.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="8">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 8 10">Cofactor biosynthesis; thiamine diphosphate biosynthesis; thiamine phosphate from 4-amino-2-methyl-5-diphosphomethylpyrimidine and 4-methyl-5-(2-phosphoethyl)-thiazole: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8 9">Belongs to the thiamine-phosphate synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.3" evidence="8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299838.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002310"/>
    <dbReference type="EnsemblBacteria" id="EEZ41278">
        <property type="protein sequence ID" value="EEZ41278"/>
        <property type="gene ID" value="VDA_002310"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0352">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1558094at2"/>
    <dbReference type="UniPathway" id="UPA00060">
        <property type="reaction ID" value="UER00141"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004789">
        <property type="term" value="F:thiamine-phosphate diphosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00564">
        <property type="entry name" value="TMP_TenI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00097">
        <property type="entry name" value="TMP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036206">
        <property type="entry name" value="ThiamineP_synth_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022998">
        <property type="entry name" value="ThiamineP_synth_TenI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034291">
        <property type="entry name" value="TMP_synthase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02581">
        <property type="entry name" value="TMP-TENI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51391">
        <property type="entry name" value="SSF51391"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00693">
        <property type="entry name" value="thiE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8 9" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="5 8 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TMP-TENI" evidence="11">
        <location>
            <begin position="6"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="HMP-PP binding" evidence="8">
        <location>
            <begin position="35"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="THZ-P binding" evidence="8">
        <location>
            <begin position="132"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="THZ-P binding" evidence="8">
        <location>
            <begin position="183"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine</name>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine</name>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine</name>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:62899"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ41278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="203" mass="22053" checksum="1B28E7BED43EF474" modified="2010-01-19" version="1">MHNYRLYLVTDENQDIETLKFVIKEAIAGGVTMVQLREKHGNVQEFIHRALVVKALLIDTGIPLIINDRVDVALAVDADGIHLGQSDMPVAIARRLLGKDKIIGLSVENSQQLDEAQNLPIDYIGLSAIYPTQTKTDTVYYWGIDGLKQAVETTSLPIVAIGGINDKNISNVSATKVAGVALVSAIAHAKSPKEACIKLLQKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYL6</accession>
    <name>D0YYL6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002379</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299989.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002379"/>
    <dbReference type="EnsemblBacteria" id="EEZ41347">
        <property type="protein sequence ID" value="EEZ41347"/>
        <property type="gene ID" value="VDA_002379"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5001">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GGDEF" evidence="2">
        <location>
            <begin position="254"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="1">
        <location>
            <begin position="396"/>
            <end position="647"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="658" mass="74955" checksum="A4AC5EBBA1C0D4E9" modified="2010-01-19" version="1">MNQEYTLFNNLQCPVWIFDIDNKKIIWANEKSLPLWEAKSLSELTSRDLSFDMSAAVEATLVDYKATFARGKTIKTWWSFTPHEVLKKYLCIFSGIPLSDGRIGMLVEVLANETTLRRDLAFSECSNLALLFNQSGQLVSTNAAFSHQFGECVNDLASFLGDIAQARQLLENAQQNRIVDQKLLCWTGQRHLWFHIEGKWLEEQQQLLLQLTNISPEREKLRQAKYNSEHDFLTGLMNRRGISSAIKISHHTKQPYSLLFLDLDGFKMINDTYGHAVGDRLLRAVSIRLRQVIQHRGLLARFGGDEFLIHVERRNITTPCAFAKEVITALNKPFHLKEVGELSIGCTVGTTNYPEDAQDIDTLVTQADMAMHRAKLRGRNCCHHFSPDMADALYRKMILRHHLTLALNANAFELYYQPIVDLKKAKLKGFEALIRWNDDDLGQISPAEFIPLAEETGQIVPLGQWILKTACRQLAEWKKKYDHSFIMSVNLSRAQLQTGLVQSVKACLDAYQIDPKQLALELTESTMLQDYSDAKQCLTELAELGIELYLDDFGTGYSSLSQLQDLPISTVKLDRSFVQGEHKGSQAIIEATQAICEKLDLKVVAEGVETEQQLDYLRQCNFDYCQGYYLGHPMPPQTIEERQFSLCHDLDINNPTIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYM4</accession>
    <name>D0YYM4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002387</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300005.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002387"/>
    <dbReference type="EnsemblBacteria" id="EEZ41355">
        <property type="protein sequence ID" value="EEZ41355"/>
        <property type="gene ID" value="VDA_002387"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1135906at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="253" mass="27251" checksum="296CB9C842DA68A7" modified="2010-01-19" version="1">MNYSIAQDALKDRVILVTGAGDGIGREAAMQYAAHGATVILLGRTVAKLEAVYDEIEQQGFPTPAIIPMDLLGATKQNYQDMADTIKQQFGRLDGVLHSAGLLGVLSPFDQIDEASFDDVMKVNVKAQFLMTQALLPLLKQASDGRIIFTSSTVGHIGRAFWGSYAISKFATEGMMQVLADELTNTNVKVNAINPGGTRTGMRAQAFPAEDPNQLKTPKDIMPLYLYLMAPEGGHIHGECIDAQPKRQPGAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYZ1</accession>
    <name>D0YYZ1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 7">Citrate synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_002504</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>acetyl-CoA + H2O + oxaloacetate = citrate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16845"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16947"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.3.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Carbohydrate metabolism; tricarboxylic acid cycle; isocitrate from oxaloacetate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 5 8">Belongs to the citrate synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300214.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002504"/>
    <dbReference type="EnsemblBacteria" id="EEZ41472">
        <property type="protein sequence ID" value="EEZ41472"/>
        <property type="gene ID" value="VDA_002504"/>
    </dbReference>
    <dbReference type="GeneID" id="57341270"/>
    <dbReference type="eggNOG" id="COG0372">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1412360at2"/>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER00717"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004108">
        <property type="term" value="F:citrate (Si)-synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd06114">
        <property type="entry name" value="EcCS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016142">
        <property type="entry name" value="Citrate_synth-like_lrg_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016143">
        <property type="entry name" value="Citrate_synth-like_sm_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002020">
        <property type="entry name" value="Citrate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019810">
        <property type="entry name" value="Citrate_synthase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024176">
        <property type="entry name" value="Citrate_synthase_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036969">
        <property type="entry name" value="Citrate_synthase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010953">
        <property type="entry name" value="Citrate_synthase_typ-I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00285">
        <property type="entry name" value="Citrate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001369">
        <property type="entry name" value="Citrate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00143">
        <property type="entry name" value="CITRTSNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48256">
        <property type="entry name" value="SSF48256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01798">
        <property type="entry name" value="cit_synth_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00480">
        <property type="entry name" value="CITRATE_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="active site" evidence="6">
        <location>
            <position position="306"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR001369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001369-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="429" mass="48244" checksum="41B72D44235D2C4A" modified="2010-01-19" version="1">MADKKATLHIEGQAPIELPIIEGTQGPAVIDVRTLGANGYFTFDPGFLATASCESQITYIDGDNGILLHRGFPIDQLANHADYLEVCYILIYGEVPTRAEYEKFRTTVTRHTMVHEQIASFFHGFRRDAHPMAVMCGVVGALAAFYHDALDINNDYHREVTAFRLLSKMPTLAAMCYKYSIGQPFIYPRNDLDYAENFLHMMFATPCEEYEVSPVVGRALDKIFILHADHEQNASTSTVRLAGSSGANPFACIAAGIASLWGPAHGGANEACLKMLEEIGSVDNIPEFIERAKDKDDPFRLMGFGHRVYKNYDPRATVMREACHDVLNELNIDDPLLDVAMELERIALSDEYFVEKKLYPNVDFYSGIILKAIGIPVSMFTVIFAMSRTIGWIAHWNEMHGDPTNRIGRPRQLYTGEDQREFSPMHERE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ04</accession>
    <name>D0YZ04_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-acetylglucosamine-6P-responsive transcriptional repressor NagC ROK family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002517</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ROK (NagC/XylR) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300239.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002517"/>
    <dbReference type="EnsemblBacteria" id="EEZ41485">
        <property type="protein sequence ID" value="EEZ41485"/>
        <property type="gene ID" value="VDA_002517"/>
    </dbReference>
    <dbReference type="GeneID" id="57341254"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1940">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1130699at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01125">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="404" mass="44041" checksum="1458D73606C02899" modified="2010-01-19" version="1">MTGGQIGNVDLVKQLNSAAVYRLIDLQGPISRIQVADVSQLAPASVTKITRQLLERGLIKEVAQQASTGGRRAISLTTESAPFHSVAIRLGRTYIELTIFDLSGKHIVSDSHRFQYSNQQELTDGLINHIRQFIAENQNVIKELVAFGITLPGLIDPETGVIEYMPHIEVDHFPLADIINEKFGVSCFVGNDIRGLALAEHYFGASRDCKDSILVSMHHGTGAGIIVNGQVFLGYNRNVGEIGHIQIDPLGDKCQCGNFGCLETVASDPAVIRHVQELLDQGYPSTLQELEELTMPAICMAANKGDELAVQALTKVGNQLGKALAMTVNLFNPQKIVLAGNITQAKDIVFPAIRRCVETQSLSTFNKDLPIVTSELYSQPTIGAFSMIKRAMLNGVLLQRLLED</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ14</accession>
    <name>D0YZ14_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nucleoid-associated protein VDA_002527</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002527</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Nucleoid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the YbaB/EbfC family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300258.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002527"/>
    <dbReference type="EnsemblBacteria" id="EEZ41495">
        <property type="protein sequence ID" value="EEZ41495"/>
        <property type="gene ID" value="VDA_002527"/>
    </dbReference>
    <dbReference type="GeneID" id="57341243"/>
    <dbReference type="eggNOG" id="COG0718">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1883809at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043590">
        <property type="term" value="C:bacterial nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1310.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00274">
        <property type="entry name" value="DNA_YbaB_EbfC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036894">
        <property type="entry name" value="YbaB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004401">
        <property type="entry name" value="YbaB/EbfC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33449">
        <property type="entry name" value="PTHR33449"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02575">
        <property type="entry name" value="YbaB_DNA_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004555">
        <property type="entry name" value="UCP004555"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82607">
        <property type="entry name" value="SSF82607"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00103">
        <property type="entry name" value="DNA_YbaB_EbfC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="109" mass="12015" checksum="13D73D032FDA9DED" modified="2010-01-19" version="1">MFGKGGMANMMKQAQQMQERMQKMQEEIANMEVTGESGAGLVKVTITGNHSVRRVNIDESLMEDDKDMLEDLIAAAFNDAARRIEEAQKEKMAGVTGGMNLPAGFKMPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ48</accession>
    <name>D0YZ48_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0115 protein VDA_002561</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002561</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0115 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300331.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002561"/>
    <dbReference type="EnsemblBacteria" id="EEZ41529">
        <property type="protein sequence ID" value="EEZ41529"/>
        <property type="gene ID" value="VDA_002561"/>
    </dbReference>
    <dbReference type="GeneID" id="57341199"/>
    <dbReference type="eggNOG" id="COG2840">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1888882at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01042">
        <property type="entry name" value="UPF0115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002625">
        <property type="entry name" value="Smr_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036063">
        <property type="entry name" value="Smr_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022990">
        <property type="entry name" value="UPF0115"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01713">
        <property type="entry name" value="Smr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00463">
        <property type="entry name" value="SMR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160443">
        <property type="entry name" value="SSF160443"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50828">
        <property type="entry name" value="SMR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Smr" evidence="2">
        <location>
            <begin position="97"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="176" mass="20020" checksum="9BFD12FF4D2247BB" modified="2010-01-19" version="1">MSNKDPNMEDDFSLFQAEVKGIKKFTHDTIIAPRKQTTKADKSKVMGKETQNHEFYFSDEFEPHLNENGPMHYARSDVSKYEVKKLRRGVYVPDMYLDMHGMTQQEAKRELAAMIAACIKESVSCACVMHGIGRHILKQKAPLWLAQHPDVMAFHQAPLEFGGDGALLVLIEIPEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ57</accession>
    <name>D0YZ57_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hypothetical VacJ lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002570</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MlaA family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002570"/>
    <dbReference type="EnsemblBacteria" id="EEZ41538">
        <property type="protein sequence ID" value="EEZ41538"/>
        <property type="gene ID" value="VDA_002570"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2853">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007428">
        <property type="entry name" value="MlaA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30035">
        <property type="entry name" value="PTHR30035"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04333">
        <property type="entry name" value="MlaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01805">
        <property type="entry name" value="VACJLIPOPROT"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="267" mass="29900" checksum="F92B8C8FB515EDF3" modified="2010-01-19" version="1">MKKTFIFPALVVVGLSGCADTPDQTDTAVSTNTIDHIETDTAAEQAMDVYDPFQSFNRVMWDINYDYLDPYLVRPVSLAYVDYVPTPIRSGISHFLANLDEPASMVNSLLMQNPKAALAHFNRFWINSIFGLAGIFDIASLADINNPGDRSFSDTTGYYGLGNGPYFMVPGYGPTTLRETTDLVDDLYPMLSYLNFWQGLAKWALEGMEDRAALVKQEALLKNSPDPYIFTRDAYIQYKDFLASDGKATVEKEAQFDDSYLDEIDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZA1</accession>
    <name>D0YZA1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Flagellar basal-body rod protein FlgG</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 7">Distal rod protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_002614</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="5 7">The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Bacterial flagellum basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the flagella basal body rod proteins family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300492.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002614"/>
    <dbReference type="EnsemblBacteria" id="EEZ41582">
        <property type="protein sequence ID" value="EEZ41582"/>
        <property type="gene ID" value="VDA_002614"/>
    </dbReference>
    <dbReference type="GeneID" id="57341138"/>
    <dbReference type="eggNOG" id="COG4786">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1488472at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009426">
        <property type="term" value="C:bacterial-type flagellum basal body, distal rod"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001444">
        <property type="entry name" value="Flag_bb_rod_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019776">
        <property type="entry name" value="Flagellar_basal_body_rod_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020013">
        <property type="entry name" value="Flagellar_FlgE/F/G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010930">
        <property type="entry name" value="Flg_bb/hook_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037925">
        <property type="entry name" value="FlgE/F/G-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012834">
        <property type="entry name" value="FlgG_G_neg"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00460">
        <property type="entry name" value="Flg_bb_rod"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06429">
        <property type="entry name" value="Flg_bbr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117143">
        <property type="entry name" value="SSF117143"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03506">
        <property type="entry name" value="FlgEFG_subfam"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02488">
        <property type="entry name" value="flgG_G_neg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00588">
        <property type="entry name" value="FLAGELLA_BB_ROD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="10" id="KW-0966">Cell projection</keyword>
    <keyword evidence="10" id="KW-0969">Cilium</keyword>
    <keyword evidence="10" id="KW-0282">Flagellum</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flg_bb_rod" evidence="8">
        <location>
            <begin position="9"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="Flg_bbr_C" evidence="9">
        <location>
            <begin position="184"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF06429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ41582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="262" mass="27940" checksum="C67BD0E5DC5D5709" modified="2010-01-19" version="1">MHPALWVSKTGLDAQQTNISTISNNLANASTVGFKKGRAVFEDLFYQNINQPGGQATQDSTLPTGLMLGAGSKVVATQKVFTQGNTQTTNNAMDMMIEGDGFFQILLPDGNMGYTRNGQFTINAEGQLVTTGSGYVVQPEIVVPEDAVGITVGTDGEVSARIRGQQENQVLGQLTTVDFINPGGLEPIGQNLFLPTGASGDAQEGTPGLDGLGTIRQSMLETSNVNVTEELVNMIEAQRVYEMNSKVISTVDQMLSYVNQQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZC2</accession>
    <name>D0YZC2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Phosphocarrier protein HPr</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_002635</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300557.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002635"/>
    <dbReference type="EnsemblBacteria" id="EEZ41603">
        <property type="protein sequence ID" value="EEZ41603"/>
        <property type="gene ID" value="VDA_002635"/>
    </dbReference>
    <dbReference type="GeneID" id="57341109"/>
    <dbReference type="eggNOG" id="COG1925">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="404807at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00367">
        <property type="entry name" value="PTS-HPr_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000032">
        <property type="entry name" value="HPr-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035895">
        <property type="entry name" value="HPr-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001020">
        <property type="entry name" value="PTS_HPr_His_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002114">
        <property type="entry name" value="PTS_HPr_Ser_P_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00381">
        <property type="entry name" value="PTS-HPr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00107">
        <property type="entry name" value="PHOSPHOCPHPR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55594">
        <property type="entry name" value="SSF55594"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01003">
        <property type="entry name" value="PTS_HPr_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51350">
        <property type="entry name" value="PTS_HPR_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00369">
        <property type="entry name" value="PTS_HPR_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00589">
        <property type="entry name" value="PTS_HPR_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0598">Phosphotransferase system</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HPr" evidence="4">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="95" mass="10129" checksum="6BC39A7283504533" modified="2010-01-19" version="1">MYQKQVEITAPNGLHTRPAAQFVKDAKAFDADITVTSNGKSASAKSLFKLQTLGLVKGAVITIAAEGAQAQEAVEKLVTLTELHEGAEIAMFREI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZD3</accession>
    <name>D0YZD3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002646</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41614">
        <property type="protein sequence ID" value="EEZ41614"/>
        <property type="gene ID" value="VDA_002646"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="38" mass="4579" checksum="0B83FF1CA5227FDF" modified="2010-01-19" version="1">MKFGQKEKIDYLREKQQREAALKAEQEKERANSEQDPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZH5</accession>
    <name>D0YZH5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator LysR family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002688</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300705.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002688"/>
    <dbReference type="EnsemblBacteria" id="EEZ41656">
        <property type="protein sequence ID" value="EEZ41656"/>
        <property type="gene ID" value="VDA_002688"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1661500at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="10"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="295" mass="33417" checksum="B4421D03B559D7B7" modified="2010-01-19" version="1">MFLWEGVTEFVAVSETESFTAAAKKIGISTAQVSRQISALENRLNTKLFYRTTRKVSLTEEGSIYYRHCRQVMDGLEEAERAITSLRGVPQGLIKMTAPVTYGEKYIVPLVNDFMLQYPEIEVAMDLTNRQMDLVEGAFDLAIRLGKLGNSSMMAKRLTTRTMYLCASPAYLEKYGMPHTLSELRHHNCLIGNHDYWRFQEKGKEKSIRIAGSLSCNSGYGLRDAVIKGIGIAQLPEYYVDEDLANGSIVPILEKFQEPDEGIWALYPHNRHLSPKVRLLVDFLAEELPKKRVDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZK7</accession>
    <name>D0YZK7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Queuine tRNA-ribosyltransferase</fullName>
            <ecNumber evidence="5">2.4.2.29</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Guanine insertion enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">tRNA-guanine transglycosylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">tgt</name>
        <name evidence="7" type="ORF">VDA_002720</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>7-aminomethyl-7-carbaguanine + guanosine(34) in tRNA = 7-aminomethyl-7-carbaguanosine(34) in tRNA + guanine</text>
            <dbReference type="Rhea" id="RHEA:24104"/>
            <dbReference type="Rhea" id="RHEA-COMP:10341"/>
            <dbReference type="Rhea" id="RHEA-COMP:10342"/>
            <dbReference type="ChEBI" id="CHEBI:16235"/>
            <dbReference type="ChEBI" id="CHEBI:58703"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:82833"/>
            <dbReference type="EC" id="2.4.2.29"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">tRNA modification; tRNA-queuosine biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the queuine tRNA-ribosyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.29" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300811.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002720"/>
    <dbReference type="EnsemblBacteria" id="EEZ41688">
        <property type="protein sequence ID" value="EEZ41688"/>
        <property type="gene ID" value="VDA_002720"/>
    </dbReference>
    <dbReference type="GeneID" id="57341008"/>
    <dbReference type="eggNOG" id="COG0343">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1165356at2"/>
    <dbReference type="UniPathway" id="UPA00392"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008479">
        <property type="term" value="F:queuine tRNA-ribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:queuosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0101030">
        <property type="term" value="P:tRNA-guanine transglycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.105">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00168">
        <property type="entry name" value="Q_tRNA_Tgt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004803">
        <property type="entry name" value="TGT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036511">
        <property type="entry name" value="TGT-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002616">
        <property type="entry name" value="tRNA_ribo_trans-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01702">
        <property type="entry name" value="TGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51713">
        <property type="entry name" value="SSF51713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00430">
        <property type="entry name" value="Q_tRNA_tgt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00449">
        <property type="entry name" value="tgt_general"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5 7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 5" id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 5" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="TGT" evidence="6">
        <location>
            <begin position="13"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="91"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="RNA binding" evidence="5">
        <location>
            <begin position="247"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="RNA binding; important for wobble base 34 recognition" evidence="5">
        <location>
            <begin position="271"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="91"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="266"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="216"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="304"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="306"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="309"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="335"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="377" mass="42931" checksum="26C770634B6967B7" modified="2010-01-19" version="1">MKLKFELDKKQGNARRGRLIFERGTVETPAFMPVGTYGTVKGMTPEEVKDTGAQILLGNTFHLWLRPGQEVMKLHGDLHDFMQWQGPILTDSGGFQVFSLGDIRKITEEGVHFRNPVNGDKIFMDAEKSMEIQKDLGSDIVMIFDECTPYPATHDEAKKSMEMSLRWAQRSRNHFDKLDNQNSLFGIVQGGVYEDLRDVSVEGLTKIGFDGYAVGGLAVGEPKEDMHRVLEHTCPQLPEDKPRYLMGVGKPEDLVEGVRRGIDMFDCVMPTRNARNGHLFVTGGVVKIRNASHKTDTTPLDPQCDCYTCRNYSKAYLHHLDKCNEILGARLNTIHNLRYYQRLMASIRKAIEEDRFDAFVEEFYARRNREVPPLQKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZN0</accession>
    <name>D0YZN0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Probable integral membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_002743</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the UPF0718 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300885.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002743"/>
    <dbReference type="EnsemblBacteria" id="EEZ41711">
        <property type="protein sequence ID" value="EEZ41711"/>
        <property type="gene ID" value="VDA_002743"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0701">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="737000at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005524">
        <property type="entry name" value="DUF318"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03773">
        <property type="entry name" value="ArsP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="88"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="281"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="313"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="339"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="381"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="423"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="457" mass="50441" checksum="C206121FE951EB25" modified="2010-01-19" version="1">MESGDGNIIFHTISVFFNMVWQVYWPLAFGLILSSFIRHLLPVETVAKNLGKTTAKSLSLTTVLGMVSSSCSYAAASLSHTLLSKKSTVANAMAFLVSSTNLIVEMFIVLVALLGWTFFWGEILGGLILIVSAAFLFERFYPKDVEQELRAKLAQEQEGSAGGHSDCGMDMFSMKSEHEDCGMDMSSMKHEHHDMGAMHMKGEHEDCGMDMSSMKHEHHDMGAMNMKGDHEDCGMDMSSMKYDHHDMSAMKPTEPQSPMMEKITKSAGFFQMDLAMIGKEILIGVVVSSILIAVVPLEGWRTLFISNDAALPMWLHSFLDVVIGIFVAMIAYVCSVGNLLLAAALWHGGISFGGVIGFILSDVLTIPMMKVYQKYYGKRPAKWMVGLLFIAILFTGLCVDAIFHGFDINVTTEGLRTINQDGFGLNLTTILNCVFIPLSIWYYRLGKKANAGMGMNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z006</accession>
    <name>D0Z006_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Flavodoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_002869</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Low-potential electron donor to a number of redox enzymes.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the flavodoxin family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301243.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002869"/>
    <dbReference type="EnsemblBacteria" id="EEZ41837">
        <property type="protein sequence ID" value="EEZ41837"/>
        <property type="gene ID" value="VDA_002869"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0716">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1961680at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001226">
        <property type="entry name" value="Flavodoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010086">
        <property type="entry name" value="Flavodoxin_lc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038996">
        <property type="entry name" value="FldA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01752">
        <property type="entry name" value="flav_long"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00201">
        <property type="entry name" value="FLAVODOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0249">Electron transport</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4 5" id="KW-0288">FMN</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="6">
        <location>
            <begin position="3"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR038996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="174" mass="19645" checksum="9144DBA9D1E780C1" modified="2010-01-19" version="1">MKIGLFYGSTTCYTEMAAEKIRDCLGHDLVSVFNIKETPISEMNSFDLLILGISTWDFGELQEDWEAVWQQLDGLDLNGKTIALFGLGDQEGYTEWYLDAMGMLHDKLLPTGVNVIGYWPNDENYQFTASKALTDDGEFFVGLALDEDSQYELSDERITTWCGQIMAEYAEALS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z041</accession>
    <name>D0Z041_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">VDA_002904</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301312.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002904"/>
    <dbReference type="EnsemblBacteria" id="EEZ41872">
        <property type="protein sequence ID" value="EEZ41872"/>
        <property type="gene ID" value="VDA_002904"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3850">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004721">
        <property type="term" value="F:phosphoprotein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 17" id="KW-0418">Kinase</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="355"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="16">
        <location>
            <begin position="376"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="13">
        <location>
            <begin position="465"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="14">
        <location>
            <begin position="722"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="15">
        <location>
            <begin position="870"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="428"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="10">
        <location>
            <position position="771"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EEZ41872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="1130" mass="127163" checksum="E7E52917EC6CFB68" modified="2010-01-19" version="1">MQTKQRFKRLQHTLMLAFLVLSITPLTLSALYFLNSHSKDLAEQSTSHLASLLENKKKQLSQFFAAKESEVQSFARSELANASGGRFYGLVGAYHQLGNINNLLNGLTRDQYFKEILTAKGQKSTTNSASYVGHERYRLMYKRYNWAFDEYLKRSDFSDILLVDLKGNVVYSAKKPQYFALNLASGKGALKGLQPTFQAISTQAQQLKQDQEVVPVAFADFNLGGNNQSEQAWFAAPIIQQGYLHSYVFFQLDINKIATLLADKPQNGQTVQTLLVGQDHHMRLPNSGDLPQQLISPAINQALAGKTGVGSLLNYNNIAVLSAFTPIKIFNHTWALVVELPEKEAFARIHQLEKIFFAAMLTAIVLVILAALWLSNSITAPLLRLTWASERVSAGDLEQKIEGTERKDEIGRLATSFARMQCSIREKMSLISKQNQELEKNIHVIKQQNDDLQTADKLKDEFLATTSHELRTPLHGMIGIAESLLAGANGPMQGAQRRQLEMLINSGQRLTNLVDDLLDYHKMRYGDLDIDKHAVDLASAVRLVLELSGHLLGTKPVRIINQIPADLPLVQADEQRLEQVLYNLVGNAIKYTSEGKIVLSATVLENQVRIQVVDTGQGIPAEQLEHIFEPLVQANTNHANYRQGAGLGLTISRQLLELMGGRLYVSSQPMVGTTFSFTLNIASDEQIRQSHDHGKIHHFQAPLCDATPIEMANLPENLNGELLLVVDDEPVNLQILNNFLRLEGYRVLTAESGKQALELVQSHKPALILLDIMMPEMSGYEVCSQLRQQYTPLELPIMMLSALGQVKDRVKGFECGANDYLTKPFNKEELTARIKAHLQAGKTEFEREKNRQLAQEIHQRKQVELSLLETQTRLLGLLESTTEAILCIQNSGRIRYANDAAAKLFKRTPEQLERHSIDELLLTHLPDELQNNHHYSGSLCFKIGEQQQNLATDILNLPEESGLKQMFIFGNSGPSPQQRVQMLEEAIDVLSSYAFDGDKDNLQQLRELGGEFTRLADKLGNDAPNKQDILRELLVDAMRTTLEVWEQDTKKTKFDLAEESGLWRVYLDRSTLQTRTLDKYLHVETLPKTPRWRTVISTIDYVLDKGSAQNIQHQQLSQMRDKLQNLLRAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z049</accession>
    <name>D0Z049_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Beta-N-acetylhexosaminidase</fullName>
            <ecNumber evidence="3">3.2.1.52</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Beta-N-acetylhexosaminidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">N-acetyl-beta-glucosaminidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_002912</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides.</text>
            <dbReference type="EC" id="3.2.1.52"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 20 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.52" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002912"/>
    <dbReference type="EnsemblBacteria" id="EEZ41880">
        <property type="protein sequence ID" value="EEZ41880"/>
        <property type="gene ID" value="VDA_002912"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3525">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004563">
        <property type="term" value="F:beta-N-acetylhexosaminidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102148">
        <property type="term" value="F:N-acetyl-beta-D-galactosaminidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.379.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025705">
        <property type="entry name" value="Beta_hexosaminidase_sua/sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015883">
        <property type="entry name" value="Glyco_hydro_20_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029018">
        <property type="entry name" value="Hex-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015882">
        <property type="entry name" value="HEX_bac_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22600">
        <property type="entry name" value="PTHR22600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00728">
        <property type="entry name" value="Glyco_hydro_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02838">
        <property type="entry name" value="Glyco_hydro_20b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00738">
        <property type="entry name" value="GLHYDRLASE20"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55545">
        <property type="entry name" value="SSF55545"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro_20b" evidence="8">
        <location>
            <begin position="157"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_20" evidence="7">
        <location>
            <begin position="284"/>
            <end position="631"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00030512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00033000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="662" mass="75372" checksum="100B8020AC85FFAC" modified="2010-01-19" version="1">MLWLKEITTSTLWRICKMSYRLDFTVLEIQESQSRFALTLHNLTDEALQGWSLHFFISRMIKPETLANASIEQLGSYVILTPNTETPIPANGHFYCEFVMGTAPFTLHDDGIPEAFISCISDGDTIVPRPVEVTTIDLGQAAVERYTTPLPEQAGTISIVPKPHHLIELGGVFIIDQFTSISTKLPAPAEGAIRWLQHEYQRHTQQELITLANGNIHYQLHDELAPSQYRLLVESDHIWLQASDKAGFVHATASLLQLLPTEPSHNADAAYTIPMVEIEDHPIYHYRGMMLDCGRHFHPLSRIKTLLDHLARYKFNTFHWHLTDDEGWRIEIDAFPELTRIGAWRGPNECIAPQFTTIDKRYGGFYSKEEVREIIAYAADRAIMVIPEIDIPGHCRAAIRSLPHLLIDPQDRSQYRSIQGYPDNVLSPAIEGTYTFIKTVLEEICELFPAPFVHIGADEVPNGVWTQSPGCQELMAKHGYQDPKELQGHLLRFAQEVLSHQDKQMMGWEEATHGEKVSKETVIFSWLSEEAGLACIKQGYPVVMQPAQYTYLDLAQGFSADEAGVDWAGKVILDKVYSYQPLAEIAEDDPTRKQILGIQTALWCELINNQSRFDYMIYPRLLAVAEVAWTAQKNRHWEDFKARLKGQLNYLDKAGINYRRCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0F0</accession>
    <name>D0Z0F0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003014</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301565.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003014"/>
    <dbReference type="EnsemblBacteria" id="EEZ41981">
        <property type="protein sequence ID" value="EEZ41981"/>
        <property type="gene ID" value="VDA_003014"/>
    </dbReference>
    <dbReference type="GeneID" id="57340535"/>
    <dbReference type="eggNOG" id="ENOG5031NI1">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2044736at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014318">
        <property type="entry name" value="Phageshock_PspG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09583">
        <property type="entry name" value="Phageshock_PspG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02975">
        <property type="entry name" value="phageshock_pspG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="79" mass="8994" checksum="1F06B80DDC86228F" modified="2010-01-19" version="1">MFELLFLLAFTAVLVFTGISVIGILVAVAAGFALMMVAGMLGLVIKLLPWIIVIAIGVYFYREHKEKQARRDNDYRRRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0G1</accession>
    <name>D0Z0G1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">30S ribosomal protein S6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rpsF</name>
        <name evidence="8" type="ORF">VDA_003025</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">Binds together with S18 to 16S ribosomal RNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the bacterial ribosomal protein bS6 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301625.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003025"/>
    <dbReference type="EnsemblBacteria" id="EEZ41992">
        <property type="protein sequence ID" value="EEZ41992"/>
        <property type="gene ID" value="VDA_003025"/>
    </dbReference>
    <dbReference type="GeneID" id="57340521"/>
    <dbReference type="eggNOG" id="COG0360">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1776954at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00473">
        <property type="entry name" value="bS6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00360">
        <property type="entry name" value="Ribosomal_S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000529">
        <property type="entry name" value="Ribosomal_S6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020814">
        <property type="entry name" value="Ribosomal_S6_plastid/chlpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035980">
        <property type="entry name" value="Ribosomal_S6_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014717">
        <property type="entry name" value="Transl_elong_EF1B/ribosomal_S6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21011">
        <property type="entry name" value="PTHR21011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01250">
        <property type="entry name" value="Ribosomal_S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54995">
        <property type="entry name" value="SSF54995"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00166">
        <property type="entry name" value="S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="96"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ41992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="128" mass="14839" checksum="65E29357F2C214B5" modified="2010-01-19" version="1">MRHYEIVFMVHPDQSEQVAGMIERYTAAIKDSGGQIHRLEDWGRRQMAYPINKLHKAHYVLMNVEAEQAVIDELESNFRFNDAVIRNMIMRTKGAITEPSPMMKAKEERFTKREERAEAQSEGEAAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0J8</accession>
    <name>D0Z0J8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Aspartate ammonia-lyase</fullName>
            <shortName evidence="5">Aspartase</shortName>
            <ecNumber evidence="3 5">4.3.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_003062</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>L-aspartate = fumarate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:16601"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="EC" id="4.3.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.3.1.1" evidence="3 5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003062"/>
    <dbReference type="EnsemblBacteria" id="EEZ42029">
        <property type="protein sequence ID" value="EEZ42029"/>
        <property type="gene ID" value="VDA_003062"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1027">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008797">
        <property type="term" value="F:aspartate ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006531">
        <property type="term" value="P:aspartate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004708">
        <property type="entry name" value="ApsA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018951">
        <property type="entry name" value="Fumarase_C_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10415">
        <property type="entry name" value="FumaraseC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="SSF48557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00839">
        <property type="entry name" value="aspA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lyase_1" evidence="6">
        <location>
            <begin position="26"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="domain" description="FumaraseC_C" evidence="7">
        <location>
            <begin position="424"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF10415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ42029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="486" mass="52815" checksum="86AD6DA3EA6F9852" modified="2010-01-19" version="1">MSQMIDLEKNEATMNVATRIEEDLLGERHVPADAYWGIHTLRAVENFNISSTTISDVPEFVRGMVFTKKAAAMANKELGAIPSEVGDYIIKACDLILETGKCMDQFPSDVFQGGAGTSVNMNTNEVVANLALELMGKEKGEYSIVNPNDHVNKSQSTNCAYPTGFRVAVYNSIIDMVEAISYLKDAFDAKGVEFANVLKMGRTQLQDAVPMTVGQEFHAFGVLLKEEIKNLKHTAELLLEVNLGATAIGTGLNAATGYQELAVKRLAEITGLPCTPAEDLIEATSDCGAYVMVHGALKRTAVKLSKICNDLRLLSSGPRAGLNEINLPEMQAGSSIMPAKVNPVIPEVVNQVCFKVIGNDTTVTFAAEAGQLQLNVMEPVIGQAVFESISLLKNACINLRDKCIDGITVNKETCEAFVFNSIGIVTYLNPFIGHHEGDIVGKICAETGKSVREVVLERGLLTEEQLDDIFSVQNLMHPEYKAKRYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0U4</accession>
    <name>D0Z0U4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Iron-sulfur cluster assembly protein CyaY</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">cyaY</name>
        <name evidence="4" type="ORF">VDA_003158</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the frataxin family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302033.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003158"/>
    <dbReference type="EnsemblBacteria" id="EEZ42125">
        <property type="protein sequence ID" value="EEZ42125"/>
        <property type="gene ID" value="VDA_003158"/>
    </dbReference>
    <dbReference type="GeneID" id="57340611"/>
    <dbReference type="eggNOG" id="COG1965">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1812841at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.920.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00142">
        <property type="entry name" value="CyaY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002908">
        <property type="entry name" value="Frataxin/CyaY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036524">
        <property type="entry name" value="Frataxin/CyaY_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020895">
        <property type="entry name" value="Frataxin_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16821">
        <property type="entry name" value="PTHR16821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01491">
        <property type="entry name" value="Frataxin_Cyay"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01219">
        <property type="entry name" value="Frataxin_Cyay"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55387">
        <property type="entry name" value="SSF55387"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03421">
        <property type="entry name" value="FeS_CyaY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01344">
        <property type="entry name" value="FRATAXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50810">
        <property type="entry name" value="FRATAXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ42125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="103" mass="11909" checksum="5F3B0909EEF67BCD" modified="2010-01-19" version="1">MNDTEYHQLAEQAFMAIEEGVEESGVDIEPEITGNVLTLEFENRSQIVINRQEPLHELWLASKSGGYHFQYQDGQWRCTRSGDEFFDVVKRECSLHAGESVDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z106</accession>
    <name>D0Z106_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mg(2+) chelatase family protein/ComM-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003220"/>
    <dbReference type="EnsemblBacteria" id="EEZ42187">
        <property type="protein sequence ID" value="EEZ42187"/>
        <property type="gene ID" value="VDA_003220"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0606">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045006">
        <property type="entry name" value="CHLI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004482">
        <property type="entry name" value="Mg_chelat-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000523">
        <property type="entry name" value="Mg_chelatse_chII-like_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32039">
        <property type="entry name" value="PTHR32039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32039:SF7">
        <property type="entry name" value="PTHR32039:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01078">
        <property type="entry name" value="Mg_chelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00368">
        <property type="entry name" value="TIGR00368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mg_chelatase" evidence="1">
        <location>
            <begin position="193"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="331" mass="35414" checksum="AA810D9B7972D9EC" modified="2010-01-19" version="1">MSLAIVHSRACVGVQAPAVTVEVHLSNGMPSFTLVGLPETTVKEAKDRVRSAIFNANFEFPSRRITVNLAPADLPKEGGRFDLPIALGILAASGQIPAESLHKYEFLGELALSGQLRPVKGALPAALAALKAKRCLIVPDRNGDQVALVGEKQHKSAPDLIQVCAHLLGQQSLSLRFQTKPDDDSLDLTQGRDMQDIIGQQQGKRALEIAAAGGHNLLFLGPPGTGKTMLASRLCDLLPPMSHDEALETAAVASLTQQSIHQGNWLQRPLRAPHHSSSMAALVGGGSIPRPGEISLAHNGILFLDETFLILMTKSYQNSIKFMNVNDLNGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z182</accession>
    <name>D0Z182_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PNPLA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_003296</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003296"/>
    <dbReference type="EnsemblBacteria" id="EEZ42263">
        <property type="protein sequence ID" value="EEZ42263"/>
        <property type="gene ID" value="VDA_003296"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4667">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07208">
        <property type="entry name" value="Pat_hypo_Ecoli_yjju_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045943">
        <property type="entry name" value="DUF6363"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037483">
        <property type="entry name" value="YjjU-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19890">
        <property type="entry name" value="DUF6363"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="1 2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="3">
        <location>
            <begin position="1"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="2">
        <location>
            <begin position="26"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DGA/G" evidence="2">
        <location>
            <begin position="147"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="28"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ42263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="281" mass="31510" checksum="ECCF2D4C870346EC" modified="2010-01-19" version="1">MRGIFASGVLDAFLENNYMPFDFAIGVSAGSTNLIGYLCGQHGRSHTIITDYSRRHDFINFARFTQGGHLTDIDWLWRTTTRNLPLNLFKYEQRNIPLYATTTNLETGQAEYIAVSRENITEAMEATCALPVAYRHNPTVSGVAMSDGGIADSIPVIEAYNRGAREITVILSKPLGFHKSETKLPWLIKSMFHDHPKFAEAVLSRAERYNAALDFIANPPADCKLTVIAPKESFQVGRLTRNLEKLEQGYQMGREAGYRLCGLIPCYGDNCYQSERLERAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1A9</accession>
    <name>D0Z1A9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Heme A synthase cytochrome oxidase biogenesis protein Cox15-CtaA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_003323</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302491.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003323"/>
    <dbReference type="EnsemblBacteria" id="EEZ42290">
        <property type="protein sequence ID" value="EEZ42290"/>
        <property type="gene ID" value="VDA_003323"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1612">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1135592at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016653">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006784">
        <property type="term" value="P:heme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003780">
        <property type="entry name" value="COX15/CtaA_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02628">
        <property type="entry name" value="COX15-CtaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="85"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="114"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="178"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="250"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="278"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="302"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ42290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="349" mass="38661" checksum="3BE5349B2FC8B20D" modified="2010-01-19" version="1">MTGSHVHQIWLSRFIVATFIFSIVVVGLGAFTRLTESGLGCPDWPGCYGFLAVPSNSDELRQAQQLYPEQPVEASKAWYEMVHRYVAGTLGVLILLLNILAWRWQEKEPLLPKLLLLLVLFQSALGMWTVTLNLMPIVVMGHLLGGFTLVSLLWLWYQKRHTEVVQTLPADKTRLLQGYLGLLLVIVIGQIALGGWTAANYAALVCTSLPICQVNWVGQFQLSAFDPIPHSASSYQYGILDYGQRVSIHVAHRIGAIVTAIVTIGAVIWLWQWRHLRLLSYGLSTVLLLQVGLGITNVVASLPLSVAVAHNVMGLTLLLVVIKANYQVWLCRRADSYQTLHSMEGGING</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1F9</accession>
    <name>D0Z1F9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_003373</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CpxP/Spy family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302594.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003373"/>
    <dbReference type="EnsemblBacteria" id="EEZ42340">
        <property type="protein sequence ID" value="EEZ42340"/>
        <property type="gene ID" value="VDA_003373"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3678">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1720629at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd09916">
        <property type="entry name" value="CpxP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012899">
        <property type="entry name" value="LTXXQ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07813">
        <property type="entry name" value="LTXXQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF034445">
        <property type="entry name" value="CpxP_Spy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0574">Periplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019980" evidence="6">
        <location>
            <begin position="26"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ42340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="161" mass="18510" checksum="A1492168DFE75D77" modified="2010-01-19" version="1">MAKLNKVLVMAIALPMVVGSASAMAFGGKHHGDHGSDKCGMHGGKKIFSQLNLTDAQQEKMKELRQENRAEMKSHRGEHRQEMKAYHDQMQDLVLSSSFDEGQARALAEKMSQQQVERRVQMLENRQKMLNILTPEQKEKYKELRQQNLEQCAERWSKDAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1L4</accession>
    <name>D0Z1L4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glutathione-regulated potassium-efflux system protein KefB</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">K(+)/H(+) antiporter</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">kefB</name>
        <name evidence="10" type="ORF">VDA_003428</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Interacts with the regulatory subunit KefG.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell inner membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefB subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302693.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003428"/>
    <dbReference type="EnsemblBacteria" id="EEZ42395">
        <property type="protein sequence ID" value="EEZ42395"/>
        <property type="gene ID" value="VDA_003428"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0475">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="941006at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015503">
        <property type="term" value="F:glutathione-regulated potassium exporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015299">
        <property type="term" value="F:solute:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01412">
        <property type="entry name" value="K_H_efflux_KefB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004771">
        <property type="entry name" value="K/H_exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020884">
        <property type="entry name" value="K_H_efflux_KefB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006036">
        <property type="entry name" value="K_uptake_TrkA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003148">
        <property type="entry name" value="RCK_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02254">
        <property type="entry name" value="TrkA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00335">
        <property type="entry name" value="KUPTAKETRKA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00932">
        <property type="entry name" value="2a37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51201">
        <property type="entry name" value="RCK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 8" id="KW-0050">Antiport</keyword>
    <keyword evidence="8" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8" id="KW-0630">Potassium</keyword>
    <keyword evidence="2 8" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="86"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="157"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="190"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="220"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="244"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="274"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="299"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="332"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="364"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="RCK N-terminal" evidence="9">
        <location>
            <begin position="409"/>
            <end position="531"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ42395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="606" mass="66049" checksum="5EEAA629B3493566" modified="2010-01-19" version="1">MASDLLAVSVTFLAAAVVAVPIAQRLGLGSVLGYLLAGIAIGPWGLALISDVDAVMHFAEFGVVLLLFLIGLELNPKKLWQMRKPILGLGGSQVLVTSLVITALMMLLALLVPSSWLMQLQWQDALVVGMGLALSSTAIALRVIEEQQLSGSGTGKAGFAVLLFQDIAVIPMLAILPILAGGGGGSWLDLAWMFGGIATLLIGGHFLLRPLFRWVVLSGVRELFNVAALLLVVGIAWAMQSLGLSMALGTFLAGVLLAESEYRHELEIAIEPFKGLLLGLFFISVGMAVNLGLLITYPILILTAVLALVSIKGLLLYILARLFGIGAKSRSQMAAILSQGGEFAFVLFTAAFSQGLLGAELTSLLLVIVSLSMVTTPFLLMGQNYWYRRSFALEQKPELDETVEDRKPRVIITGFGRFGQVVGRLLFANKIKVTILERDPSQIQFLRKFGYKVYYGDATQIDLLRAAGAEKAEAIIICTDDPAEVMEVVTLCQQYFPHLQVLARARSRIEAHQLLSHGVKGFSRETFAGALDLGRQALISLGMHPYKAKRAAEHFQKLDAQALYDLLPHHSEDVHLTSRAKEARKELEELFDREMRGEQERHHGWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1N2</accession>
    <name>D0Z1N2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7 9">50S ribosomal protein L16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rplP</name>
        <name evidence="11" type="ORF">VDA_003446</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 9">Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7 9">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the universal ribosomal protein uL16 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302799.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003446"/>
    <dbReference type="EnsemblBacteria" id="EEZ42413">
        <property type="protein sequence ID" value="EEZ42413"/>
        <property type="gene ID" value="VDA_003446"/>
    </dbReference>
    <dbReference type="GeneID" id="57340097"/>
    <dbReference type="eggNOG" id="COG0197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1786618at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01433">
        <property type="entry name" value="Ribosomal_L16_L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01342">
        <property type="entry name" value="Ribosomal_L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016180">
        <property type="entry name" value="Ribosomal_L10e/L16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036920">
        <property type="entry name" value="Ribosomal_L10e/L16_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000114">
        <property type="entry name" value="Ribosomal_L16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020798">
        <property type="entry name" value="Ribosomal_L16_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12220">
        <property type="entry name" value="PTHR12220"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00252">
        <property type="entry name" value="Ribosomal_L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00060">
        <property type="entry name" value="RIBOSOMALL16"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54686">
        <property type="entry name" value="SSF54686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01164">
        <property type="entry name" value="rplP_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00586">
        <property type="entry name" value="RIBOSOMAL_L16_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="7 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7 9" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="2 7 9" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L16" evidence="10">
        <location>
            <begin position="4"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ42413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="136" mass="15293" checksum="BC06C5012E3DC35E" modified="2010-01-19" version="1">MLQPKRTKFRKAFKGRNRGLANGTDVSFGEFGLKAVGRGRLTARQIEAARRAMTRHIKRQGQIWIRVFPDKPITSKPLEVRQGKGKGNVEYWVAQIQPGKVLYEMGGVPEALAREAFDLAARKLPIKTTFVTKAVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1W0</accession>
    <name>D0Z1W0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Intermembrane phospholipid transport system permease protein MlaE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">VDA_003524</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell inner membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the MlaE permease family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303692.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003524"/>
    <dbReference type="EnsemblBacteria" id="EEZ42491">
        <property type="protein sequence ID" value="EEZ42491"/>
        <property type="gene ID" value="VDA_003524"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0767">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1253502at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003453">
        <property type="entry name" value="ABC_MlaE_Proteobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030802">
        <property type="entry name" value="Permease_MalE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30188">
        <property type="entry name" value="PTHR30188"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02405">
        <property type="entry name" value="MlaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00056">
        <property type="entry name" value="TIGR00056"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="48"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="99"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="144"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="195"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="239"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ42491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="260" mass="27927" checksum="FA23502A8A59F3AA" modified="2010-01-19" version="1">MITDFIAAIGRRTLNLCKTVGRASLMLYGALICKPQPRKMFPLLLKQLYSVGVLSIAIILVSGLFIGMVLSLQGYIVLVDFGAETSLGQMVALSLLRELGPVVTALLFAGRAGSALTAEIGLMKATEQLSSMEMMAVDPLRRVIAPRFWAGVISMPLLAMMFTAVGIWGGQLVGVDWKGIDYGSYWSVMQSSVDVWYDIGNGLLKAVVFAITVTWIAVFNGYDAVPTSEGISRATTRTVVNSSLAVLGLDFVLTALMFGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z237</accession>
    <name>D0Z237_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Anaerobic glycerol-3-phosphate dehydrogenase subunit B</fullName>
            <shortName evidence="4">Anaerobic G-3-P dehydrogenase subunit B</shortName>
            <shortName evidence="4">Anaerobic G3Pdhase B</shortName>
            <ecNumber evidence="4">1.1.5.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">glpB</name>
        <name evidence="6" type="ORF">VDA_001773</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:18977"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.1.5.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Polyol metabolism; glycerol degradation via glycerol kinase pathway; glycerone phosphate from sn-glycerol 3-phosphate (anaerobic route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Composed of a catalytic GlpA/B dimer and of membrane bound GlpC.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the anaerobic G-3-P dehydrogenase subunit B family.</text>
    </comment>
    <dbReference type="EC" id="1.1.5.3" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298672.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001773"/>
    <dbReference type="EnsemblBacteria" id="EEZ40741">
        <property type="protein sequence ID" value="EEZ40741"/>
        <property type="gene ID" value="VDA_001773"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3075">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1152849at2"/>
    <dbReference type="UniPathway" id="UPA00618">
        <property type="reaction ID" value="UER00673"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052591">
        <property type="term" value="F:sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019563">
        <property type="term" value="P:glycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006072">
        <property type="term" value="P:glycerol-3-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00753">
        <property type="entry name" value="Glycerol3P_GlpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-binding_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009158">
        <property type="entry name" value="G3P_DH_GlpB_su"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000141">
        <property type="entry name" value="Anaerobic_G3P_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03378">
        <property type="entry name" value="glycerol3P_GlpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2 4" id="KW-0288">FMN</keyword>
    <keyword evidence="3 4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_2" evidence="5">
        <location>
            <begin position="4"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="440" mass="48839" checksum="75C5793AC24FA2F9" modified="2010-01-19" version="1">MKFDTLVIGGGVAGLSGAIRCAEAGLKTAVVAAGQSALHFSSGSIDLLSRLPDGQLVEKPFDAFTELALQSPNHPYSKLGSDVVKRALEWYQHTMAKRGIELSHQADFTNHLRLTPMGTFRATWLSQQTVHPFPLHNLSKGIQRLALVTMDGFRDFQPELAADNLRKLSQFNHVEIITAAVELPDFAKMQRNPCEFRSIDIGRVLKDEAKLKVFADDMKIRVGRADLVVVPAVFGNGDGAKVIKRLEELTGYNICELPTMPPSLLGIRIEEAMKAYFKSLGGLILVGDEVKQGVFEHGRLKHIFTRNHWDMPLQAEHYLIATGSFFSKGMTAHRTHIEEPIFNLDMAENSHRDHWYQKQFFAKQAHPFMAIGIESNTQLQPSIQGQTIENLYCAGALMAHYDPVFQGCGSGVAISTGFYVAEQIIKQHQQTEQQVEGATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z264</accession>
    <name>D0Z264_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Anaerobic sulfite reductase subunit B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001911</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="2">Binds 1 [2Fe-2S] cluster per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="1">Binds 1 FAD per subunit.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298920.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001911"/>
    <dbReference type="EnsemblBacteria" id="EEZ40879">
        <property type="protein sequence ID" value="EEZ40879"/>
        <property type="gene ID" value="VDA_001911"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0543">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1109542at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006221">
        <property type="term" value="P:pyrimidine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012165">
        <property type="entry name" value="Cyt_c3_hydrogenase_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019480">
        <property type="entry name" value="Dihydroorotate_DH_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014260">
        <property type="entry name" value="Sulphite_reductase_B"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10418">
        <property type="entry name" value="DHODB_Fe-S_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006816">
        <property type="entry name" value="Cyc3_hyd_g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02911">
        <property type="entry name" value="sulfite_red_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="1" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="3">
        <location>
            <begin position="19"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="78"/>
            <end position="80"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="245"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="250"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="253"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="261"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR006816-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR006816-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="277" mass="31271" checksum="A84F2FA0CC711705" modified="2010-01-19" version="1">MCQHDSTHQCNCGRHNNTLLPKAYKILEITRYTDAEWNFRVEKDFPARLGQFVEVSLPMYGEAPISVSDCGEDYIDLLIRKVGKVTNKLFELNVGDCVWMRGVHGNGYPINDYNGKHLIVIAGGTGVAPVKGLIQHFSEQPELLSGMDAILGFRNQNAVLYRQCMPLWRDNINLITTLDEGEANNDFCIGRVTDYFEQLDLSQLENTQAIVVGPPIMIKFAVQALLNKGLKKEQIWVDYERKMACAVGKCGHCRIGDKYVCVDGPVFRFDQAEYLVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2F8</accession>
    <name>D0Z2F8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000609</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000609"/>
    <dbReference type="EnsemblBacteria" id="EEZ39589">
        <property type="protein sequence ID" value="EEZ39589"/>
        <property type="gene ID" value="VDA_000609"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031DNS">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024409">
        <property type="entry name" value="DUF3833"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12915">
        <property type="entry name" value="DUF3833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="202" mass="23417" checksum="D2390CB7FB209DCB" modified="2010-01-19" version="1">MASKYLQIFMMLLILPWLLSCSQKLSDYQNMQPKLDLFEYFNGHVIAWGMVQDYTHTQTRRFEVTILGTVKDNQLTLVEDFIFSDGETQQRIWHITQLSEGVYQGTANDVIGTAMGKSQGNAVNWRYTLDLPVGDDSYQVQFDDWMYLQDERHLFNLADIKKFGIKVGQVTLFFQKQPATKNPIVKSTISKNSISKNIEFKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2J2</accession>
    <name>D0Z2J2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">D-alanine--D-alanine ligase</fullName>
            <ecNumber evidence="6">6.3.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">VDA_000643</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Cell wall formation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + 2 D-alanine = ADP + D-alanyl-D-alanine + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:11224"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57416"/>
            <dbReference type="ChEBI" id="CHEBI:57822"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="14">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="14">Binds 2 magnesium or manganese ions per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the D-alanine--D-alanine ligase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.4" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000643"/>
    <dbReference type="EnsemblBacteria" id="EEZ39623">
        <property type="protein sequence ID" value="EEZ39623"/>
        <property type="gene ID" value="VDA_000643"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1181">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008716">
        <property type="term" value="F:D-alanine-D-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000291">
        <property type="entry name" value="D-Ala_lig_Van_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005905">
        <property type="entry name" value="D_ala_D_ala"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011095">
        <property type="entry name" value="Dala_Dala_lig_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07478">
        <property type="entry name" value="Dala_Dala_lig_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039102">
        <property type="entry name" value="Ddl/VanB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01205">
        <property type="entry name" value="D_ala_D_alaTIGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00843">
        <property type="entry name" value="DALA_DALA_LIGASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00844">
        <property type="entry name" value="DALA_DALA_LIGASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0133">Cell shape</keyword>
    <keyword evidence="13" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7 17" id="KW-0436">Ligase</keyword>
    <keyword evidence="14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12 14" id="KW-0464">Manganese</keyword>
    <keyword evidence="14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="16">
        <location>
            <begin position="77"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR039102-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EEZ39623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="287" mass="32026" checksum="D1309361939541BD" modified="2010-01-19" version="1">MKKEGWFNANNALCQLNLDRTLQTGDTKQIINYVIPCVHGFPGETGDLQSFLDMAGLPYLGCGAEASRNCFNKITTKLWFDALDIPNTPYVFLSENNEDAHTKASEAFDKWGKVFVKAASQGSSVGCYSVTDKANLAAVVNDAFGYSDQVLIEKSIKPRELEIAAYQYGDELIITKPGEVSCPDDKFYSYEEKYSSDSHSTTAVEATNLSEEQVEALRECARKAFVHMKLKDLSRIDFFLSEDNEILLNEINTFPGMTPISMFPKMLENHGHSFTKFIEQAIKSAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2N3</accession>
    <name>D0Z2N3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000684</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305053.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000684"/>
    <dbReference type="EnsemblBacteria" id="EEZ39664">
        <property type="protein sequence ID" value="EEZ39664"/>
        <property type="gene ID" value="VDA_000684"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="750230at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="3"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="292" mass="32917" checksum="27CC577F5238FD4F" modified="2010-01-19" version="1">MKVSFDDLYLFMLTVRHGGISSAAKAYSMQRSKVSRRLQELEKSIGCQLLIRTTRHIELTENGRALYEQISQPLTSVNQAVNLLESRQKELQGVLRVAVPAALITSSMFSALIERYAQDFPGVALEIEQRQDSVDLKRENIDLQLIPNNIKVVNLDYVQQTLLPFPCVLVASPNYLVSKPEPKHFDDLYDHKILVSRYNVNALPDELNKRLISDDLHLIQHMAITGHGIALLPLILVRSALEAGDLCCVLADEKHPEIKLTLVYPATQYLPEKTRAMVKLLRDVFVHGVASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2P8</accession>
    <name>D0Z2P8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000699</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305093.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000699"/>
    <dbReference type="EnsemblBacteria" id="EEZ39679">
        <property type="protein sequence ID" value="EEZ39679"/>
        <property type="gene ID" value="VDA_000699"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5032XQ5">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1765821at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="17"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="199" mass="22480" checksum="80DA2BED51518D9B" modified="2010-01-19" version="1">MITQSVRSDNGGREGKWVALSIATILAVSALLLPYHQAAQEEQLLAAHQQAVADLNTENIAMVAELRLAHEEIRNLYTDNQIDSASSKLALWPDLKELEALWLAPFVQDQSWERKGKHQWEKVTDSVYFGMNILQKGANSVVLISEYEEPEIWFAQDFDNAMTATSLSSFTDLKTIRTKLIADNWQQVVFDSHSASHQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2Q6</accession>
    <name>D0Z2Q6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acriflavin resistance protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000707</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305115.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000707"/>
    <dbReference type="EnsemblBacteria" id="EEZ39687">
        <property type="protein sequence ID" value="EEZ39687"/>
        <property type="gene ID" value="VDA_000707"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0841">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="145346at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="334"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="358"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="391"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="433"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="465"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="534"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="866"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="892"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="918"/>
            <end position="943"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="964"/>
            <end position="983"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="995"/>
            <end position="1022"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="1037" mass="115846" checksum="B87FF5595C2A4032" modified="2010-01-19" version="1">MNRTSRGLIAWFTYNPVAANLLMLIVMVGGVISIGLINKEIFPSFALNRISITTVYSGAAPEEIEKTINGKIEQTLTGLNGIKRMTSRAVESQGVVVLELEKNTDIDDIYQKVKQRVDAITTFPLDIETPTVLKDEFLSNVVYLSVYGDASDRQLKEFAKQLKDSLLLNTSATNAELSGVKDYEIAIEINEYQRRKHNLTLSQIAKAIEQQSIDLPSGSIKALDGDLLVRAKGQRKLGDQFSDVVVKYNGDGSRVYLTDIAKISDGFAEQVILNRFNQQRAAVIQIRNLTSEDASQIAKEVSQFAKDEQAKLPEGIYIDSWADMSHYLEGRLNMMLSNMLYGGILVFLILALFLELRLAFWVILGLPFCFLGTLLLMPFEGIGVSINLISLFGFILVLGIVVDDAIVVGESVYTEVEKQGNSIETVIKGAKRVAIPATFGVLTTIAAFLPMLLSDNPRTEFFKSIGWVVVLCLIFSLIESKWILPAHLARSKLVDNTQNKGRLSQWKFQFNQRVSLFIDCDYRRFIRFCLSQKYSVLATFIGVLIIALSLVFSGQLRWVFFPKLPSDYIQVMVDMERSSSDQQNKRVALQLEQALYQVDEHYQTELGLPVVKHSFLNMSDDSTMFVLVELEKGENLPVSSFDILEQWKSAIPPLVGVKKIRYEASIGRSTGDIQFSLKGKELRQLQQAAQALKYEISMFDGTYNIEDDLASQNQEAILKLKPIGQALGLTLADVATQVRHAFYGYEVDRVLRDKEEVKVMVRAPKMERTSLGYLQRLFILLPNGNQVPFSEVASVELEPAFTQVNRVNSERAVVVSANVFKNEASPSHIVKTLKQEVIPRLKNQYPNVSFDLDGEVKDEQDTQSSLARDAVIALFTIYALMAIPLRSYVQPLIIMSVIPFGIIGAIAGHYFAGLTLNLLSVFGILALAGVVVNDSLVLVTFINRAREQGMKIEQAVEEAGCHRFRAIVLTSLTTFCGLAPILLEKSLQAQIVIPMATSLAFGILFATVVTLILVPSLYLILVDIKRWGWKLKRFYTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2X7</accession>
    <name>D0Z2X7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Alpha-1,6-galactosidase putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000778</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305325.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000778"/>
    <dbReference type="EnsemblBacteria" id="EEZ39758">
        <property type="protein sequence ID" value="EEZ39758"/>
        <property type="gene ID" value="VDA_000778"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3345">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="469334at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004557">
        <property type="term" value="F:alpha-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14791">
        <property type="entry name" value="GH36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002252">
        <property type="entry name" value="Glyco_hydro_36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="572" mass="64459" checksum="22DA17D4314702C8" modified="2010-01-19" version="1">MSCTLNSIPFQPAANIDVSICCEQLNVVYLIAESTHSLSATTLIGRFTFPYQGTESIIGDGFQMLAQTGGTIEQPQAIGRCPDNNSEYRIYPHDAPNRYYNYLVIEQEGQFTLFGFTSCHRFAGYFEIHDQSIYAFIDGEHCVFKPDTANGITLEQIVTVVGSNLHDVYQSFTKAINRNHPKRNDSQRSPVGWCSWYAYYAGVSASDIEQNIRCMTGENKNIEWVLLDDGYQAYMGDWLTPSERFSDGIQTVIAKIKQQGKQPGIWLAPFIAEPSSEIFKQHPNWFVCHQEGELLKAETVTYGGWRCTPWYILDTSHPEVQAHLTSVVKTMREEWGVELFKLDANYWGTLKGARYKKDCTGVAAYRLGMEAIAKGAGSAWLLGCNAPMWPSLGLVDAMRVSDDVERNPHRFSQIAQETFYRSWQHLALWHIDPDCVTLIDLASQKTSHNSYLFHRDVVLASGGLLLSGDPLAHWTPFAQQSFHRLVERQCQTPNSAEFNDLSLAQAELTLDKQQTIYIGFNYNDANARTVTFDAKGNKDWFDFWTGECVATSVSTYQVQLSPGLNSCSVVAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2Y9</accession>
    <name>D0Z2Y9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein TonB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">VDA_000790</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cell inner membrane</location>
            <topology evidence="1 9">Single-pass membrane protein</topology>
            <orientation evidence="1 9">Periplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the TonB family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305358.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000790"/>
    <dbReference type="EnsemblBacteria" id="EEZ39770">
        <property type="protein sequence ID" value="EEZ39770"/>
        <property type="gene ID" value="VDA_000790"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0810">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2074833at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031992">
        <property type="term" value="F:energy transducer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015343">
        <property type="term" value="F:siderophore transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003538">
        <property type="entry name" value="TonB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006260">
        <property type="entry name" value="TonB/TolA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037682">
        <property type="entry name" value="TonB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03544">
        <property type="entry name" value="TonB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01374">
        <property type="entry name" value="TONBPROTEIN"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01352">
        <property type="entry name" value="tonB_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="domain" description="TonB_C" evidence="11">
        <location>
            <begin position="138"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="53"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ39770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="218" mass="23987" checksum="8F9CFD7A186EE268" modified="2010-01-19" version="1">MLRVLMAFPLAILLAGGLFTFMAWMVDNGSRQEPESTPPLSFNMVMVEQESEVQRRQRVVPPKPEAPKPPPQIMPSQSKPTSVSTLPVASISALGLDTSISGIAVSAPKFGKIEGSANLGAGINVGSNQQAMPLYRVEPRYPARALKQGAEGYVVLQFTIDTQGRPSDISVVEAKPRRLFERDAMRALRKWKYQAKVIDGQAVEQPRQTVKLEFKINQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z304</accession>
    <name>D0Z304_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Acetyltransferase</fullName>
            <ecNumber evidence="4">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_000805</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305399.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000805"/>
    <dbReference type="EnsemblBacteria" id="EEZ39785">
        <property type="protein sequence ID" value="EEZ39785"/>
        <property type="gene ID" value="VDA_000805"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0110">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1878940at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016407">
        <property type="term" value="F:acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039369">
        <property type="entry name" value="LacA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024688">
        <property type="entry name" value="Mac_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43017">
        <property type="entry name" value="PTHR43017"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12464">
        <property type="entry name" value="Mac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01266">
        <property type="entry name" value="Mac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Mac" evidence="5">
        <location>
            <begin position="5"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ39785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="185" mass="20253" checksum="314CF0800F818124" modified="2010-01-19" version="1">MSSEKEKMLAGLPYDAWDPQLLNERMRAKAYCHKFNLADPTLLDERMAILSDLLHVEGTAHLEPNFYCDYGYNIHLGDNFYANHNLTIIDVCKVDIGTNVLIAPHVLISTGTHPTNPVERRSTEYGKPIKIGNDVWIGGNASILPGVTIGDRVVIGAGSVVNKDIPSDSIAVGNPCRVIKKLADS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z326</accession>
    <name>D0Z326_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Purine nucleoside phosphorylase DeoD-type</fullName>
            <shortName evidence="1">PNP</shortName>
            <ecNumber evidence="1">2.4.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">deoD</name>
        <name evidence="3" type="ORF">VDA_000827</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a purine 2'-deoxy-D-ribonucleoside + phosphate = 2-deoxy-alpha-D-ribose 1-phosphate + a purine nucleobase</text>
            <dbReference type="Rhea" id="RHEA:36431"/>
            <dbReference type="ChEBI" id="CHEBI:26386"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57259"/>
            <dbReference type="ChEBI" id="CHEBI:142361"/>
            <dbReference type="EC" id="2.4.2.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a purine D-ribonucleoside + phosphate = a purine nucleobase + alpha-D-ribose 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:19805"/>
            <dbReference type="ChEBI" id="CHEBI:26386"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57720"/>
            <dbReference type="ChEBI" id="CHEBI:142355"/>
            <dbReference type="EC" id="2.4.2.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homohexamer; trimer of homodimers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PNP/UDP phosphorylase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.1" evidence="1"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305459.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000827"/>
    <dbReference type="EnsemblBacteria" id="EEZ39807">
        <property type="protein sequence ID" value="EEZ39807"/>
        <property type="gene ID" value="VDA_000827"/>
    </dbReference>
    <dbReference type="GeneID" id="57342733"/>
    <dbReference type="eggNOG" id="COG0813">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1028277at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004731">
        <property type="term" value="F:purine-nucleoside phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042278">
        <property type="term" value="P:purine nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09006">
        <property type="entry name" value="PNP_EcPNPI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01627">
        <property type="entry name" value="Pur_nucleosid_phosp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004402">
        <property type="entry name" value="DeoD-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000845">
        <property type="entry name" value="Nucleoside_phosphorylase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43691:SF2">
        <property type="entry name" value="PTHR43691:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01048">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="SSF53167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00107">
        <property type="entry name" value="deoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PNP_UDP_1" evidence="2">
        <location>
            <begin position="16"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphate binding" evidence="1">
        <location>
            <begin position="87"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Purine nucleoside binding" evidence="1">
        <location>
            <begin position="179"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Purine nucleoside binding" evidence="1">
        <location>
            <begin position="203"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="204"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="4"/>
        </location>
        <ligand>
            <name>a purine D-ribonucleoside</name>
            <dbReference type="ChEBI" id="CHEBI:142355"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="20"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="24"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="1">
        <location>
            <position position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="235" mass="25633" checksum="3C74F55D9EF57DAA" modified="2010-01-19" version="1">MTAHIAGSIEDFASTVIMPGDPLRAKYIAETYLDDAKLVTDIRNMLGYTGYYKGHRISVMGHGMGIPSMVLYGHELINNFGVKRIIRIGSIGATQKDVQMRDVILAQAAGTDSPTNAKRSSGYQMATSATFELLHSAYITAQEKEINVKVGNIFTGDLYYDPDEDLIAALERFGVLGIDMEVAGLYGLAHQFGIESLAILTVSDHCITGEETTAEERQLSFNNMIEIALETAIKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z329</accession>
    <name>D0Z329_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Anaerobic dimethyl sulfoxide reductase chain B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">VDA_000830</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305467.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000830"/>
    <dbReference type="EnsemblBacteria" id="EEZ39810">
        <property type="protein sequence ID" value="EEZ39810"/>
        <property type="gene ID" value="VDA_000830"/>
    </dbReference>
    <dbReference type="GeneID" id="57342730"/>
    <dbReference type="eggNOG" id="COG0437">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1762646at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014297">
        <property type="entry name" value="DMSO_DmsB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13247">
        <property type="entry name" value="Fer4_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12800">
        <property type="entry name" value="Fer4_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02951">
        <property type="entry name" value="DMSO_dmsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="10">
        <location>
            <begin position="5"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="10">
        <location>
            <begin position="60"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="10">
        <location>
            <begin position="92"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ39810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="207" mass="23210" checksum="EE0CF10FBBA7FD03" modified="2010-01-19" version="1">MTQQYGFFVDTTKCTGCKTCQVSCKDKNTLPIGVNFRRVYEYTGGEWTKQHNDTWQQNIFAYYVSISCNHCSQPACTKACPTGAMHKREQDGLVVVDEQVCVGCRYCEMACPYGAPQYNSEKKHMTKCDGCFELIALGKKPICVSSCPLRALDFGPIDDLRVKYGDTADIAPLPNSELTKPSLVIQHNRHAKPTLDKQGYIANKAEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3B3</accession>
    <name>D0Z3B3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative tail fiber protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000914</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305706.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000914"/>
    <dbReference type="EnsemblBacteria" id="EEZ39894">
        <property type="protein sequence ID" value="EEZ39894"/>
        <property type="gene ID" value="VDA_000914"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5301">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2101640at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="374"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="443"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="100"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="375"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="1008" mass="107777" checksum="65873E5BEE6F8C8D" modified="2010-01-19" version="1">MLVKGILSDAADQCIPKGIIQIVSINTSESVLEGSTVWIKADNEGHYSFTLLPGSYLIYAQSGRQNDVVYLGETIVTDDTPDGSLNSIVGITTPVLPPQVQQAVNAANKATRSAEDANDKYQDLIELAKTVTNSINDLVTTVNHVENLSQSVEGYALASGNALQGSLRIKAEVGAVNQSVRLVKDEILSIQKNIIHLKSDAETFSSKASSSAQKAQKQANSAVLSANNAAADSQKTFRLMTVVEKYRDDVMGALDETHQSLEWLKFMQVQFDTKLQEMTLIDEHLSILAREIEKNKQKVEQLRLNARESAGNAATSALRAEHEANRAEVAASIDIVREAEKQAKSSKSEADKSLSASLVSVNAKNVAVAKANEAKQSELSATTSAQNAEQNSLTAKEQAKLSTEKASSAAISAKNSKSSEKSALEAASEAALNSTATKQSANLASSHAVTAGESANTAEQKADDAANQASIATQQAGIAKSNADASLNSQTLAANSVELASNQAKLASNSAKVAAEKAMIAINQVSLAQQEAAKSRVNAGGAAQSAKDSERSSQTSIAKADVAAKNAGLSATHAIEASQSFIRALSAEESAISAAKRAETAVASLSGAMIEQGGVDLSKGVAPQPPLDINGAKRACFWKVTAAGTVNNIEYGVDDSIVYSASMDTYYKIDNTENVTSVNGHRGVVNLTKKDVGLNLVPNKTHTESVLADSVPIRDHSGDVSSRLFRSNYTEQQTISGALAFRIDNVTDNYIRFCSNQEAIRTWLSLYSKDESDNKYLLKSVQDSFAQKINPSFTGRVSISSDESTSDAPCLLSLQALSTRGHPHPTPIINDNQGLDSDADIYKYRNTFTGSISYEYIKSLNIDLTGKNGKYVKIASVYIPQDGSTAEIEIIGGAGFNLGSHTQCDHSRIIIRSGNGTPKGINCRVYAHQIHTYRFFTKIYTHNVTSDWYDIYLLVVNAYASNLIFKFSSSVGCYIKPSLRDPLTLSALPSGSQKGVIYLYSYSQDDIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3D5</accession>
    <name>D0Z3D5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000936</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305770.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000936"/>
    <dbReference type="EnsemblBacteria" id="EEZ39916">
        <property type="protein sequence ID" value="EEZ39916"/>
        <property type="gene ID" value="VDA_000936"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502ZASF">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1856872at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010183">
        <property type="entry name" value="Phage_lambda_Bet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018330">
        <property type="entry name" value="RecT_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03837">
        <property type="entry name" value="RecT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01913">
        <property type="entry name" value="bet_lambda"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="285" mass="32315" checksum="4602F06B98E09B4F" modified="2010-01-19" version="1">MLNNQATTFEQQYPLVAQRGLDQSTWGALQNSVFPGAKEESILMAVDYCLSRQLDILLKPVHLVPMSVKTPHKDHHGKDIYEYRDVVMPGIGLYRIQADRSGTYAGADEPEFGPIITMQLGDDKSVMDYQFPEWCKYTVYKLIGDRIVTFSAKEYWIENYATASKYTSTPNAMWKKRPYAQLAKCAEAQALRKAWPDIGQAPTAEEMEGKDFTSIEKDITPQKQPAPQITFYPTEMFDANLSNWRNAIQSGKRTAEQIISLVESKGALTEGQKSVIYKCELNEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3H9</accession>
    <name>D0Z3H9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulators LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000980</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305899.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39960">
        <property type="protein sequence ID" value="EEZ39960"/>
        <property type="gene ID" value="VDA_000980"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1661500at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="300" mass="33136" checksum="9078E7C7798A4D2C" modified="2010-01-19" version="1">MDKLGAMRAFVRVVQTGSFSATGRELNTSQTAISKKVAALEKEIGVKLLTRNSRELALTPSGTEYFNKCVAILGEIDEAEASAREDVAVPKGVLRISAPIAFSRLVLASLLSEFNSLYPEISIDLLASDQHVDLISSGVDVAIRARNLEDSTLIARHLFDNVLMLFASPDYLAKNGTPNKPEDLLDHNCLVYSRLHSVNTWSFSCKQQEHLISVHGSFRCDNGDVLLDAALAGLGITHLPKWMVSRYVESGELIPLLVDYEGQKLPFNAVYLQNRYVPLKVRCFVDFLKQKIDGCGEFFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3K1</accession>
    <name>D0Z3K1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001002</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305955.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39982">
        <property type="protein sequence ID" value="EEZ39982"/>
        <property type="gene ID" value="VDA_001002"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019374" evidence="1">
        <location>
            <begin position="21"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="114" mass="12254" checksum="4A9D01F2CF727219" modified="2010-01-19" version="1">MKKQILAIGLLALGSTSAFANVDDSLEQICASQGGAMTSLSQGGTIEFLTDADGVTHKRFSMNDNIVNIDLDNVSDQIKNQIIDSVKFGYDLEMCIASNGKVLPMMGRISTEHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3Y7</accession>
    <name>D0Z3Y7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GGDEF and EAL domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001140</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306321.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001140"/>
    <dbReference type="EnsemblBacteria" id="EEZ40118">
        <property type="protein sequence ID" value="EEZ40118"/>
        <property type="gene ID" value="VDA_001140"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2199">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2200">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="149"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="3">
        <location>
            <begin position="260"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="2">
        <location>
            <begin position="400"/>
            <end position="641"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="641" mass="72875" checksum="8F9700AF98523EF4" modified="2010-01-19" version="1">MSLYKKQIINIASIFTLTIGALTINQVATDRDLIAISEKLIIKSELQLIRNYLLTTPSLTEKNLTHIESDIGQLISHENFSHIEISIDDQQIKWLSPIEPKSLSYQFVTAVFPETDYSISEKLVTPLNNQIAIKLVSSSSNMVKEKNSALIRILFANGTILLFGLGSLYWFTRREFNELQQVIQHLTKNPQSPLPMAKNEEFKIITKAFNSLITQLNLNFQAQAKEALKLKEQAYKDPISLLGNRSFFIHQLNSWLQESSKGGVILSKLQFVDDYYQKEGYQIGDQLIKEIATYLEQAVRNTNATVARLSYDEFAILIPSETLENLKLIGENILLMPEQLKLDEELTLNQTRIGIVLCSEPTTTSNLLAQLDNSLAQAASTPEHPIYVTTDITTKAAFGKQQWKQILLDAIEKDNFSYQYQSVQIGADQIYHYEIFTAIHDSTSRYSANQFLNAIEDLSLGSLFDRNVIIHAINTLLAKKQMPPIAINLTTNSINDPAFVRWLTTTLDTNKNLSHRLYFEIPESCCVRHFDATSILCSTIRFHHFGIGIDNYGRYFQSLNYLQELRPDYVKIDFVYTNQLNDPTKANVLSSICRTAHSLNIKTIATRVETETQKERLSDLFITGFQGFVIEKGITEEKIIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z482</accession>
    <name>D0Z482_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MSHA pilin protein MshA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000338</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304088.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000338"/>
    <dbReference type="EnsemblBacteria" id="EEZ39320">
        <property type="protein sequence ID" value="EEZ39320"/>
        <property type="gene ID" value="VDA_000338"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2165">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1986406at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="194" mass="21371" checksum="C79E616221ECBE22" modified="2010-01-19" version="1">MKIKINRGFTLIELVVVIVILGILAVTAAPKFLNLQKDARISTLKATKGALETAIQLVKAKAEINLIAPENCKSFNGTNNDNETAGCIKINGHEVLVYSNTHYPDLVFGNNPSKNNKVVNNLKSILSIDAYPRKSQKYQEDMSPTGSGFLVYGSLDHDVYIMPNVKDAYKNILNCRIQYNGTLEKPITLITKGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4A3</accession>
    <name>D0Z4A3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Thioredoxin 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_000359</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thioredoxin family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304144.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000359"/>
    <dbReference type="EnsemblBacteria" id="EEZ39341">
        <property type="protein sequence ID" value="EEZ39341"/>
        <property type="gene ID" value="VDA_000359"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3118">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1630944at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005746">
        <property type="entry name" value="Thioredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01068">
        <property type="entry name" value="thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Thioredoxin" evidence="6">
        <location>
            <begin position="20"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="144" mass="16018" checksum="551FC0CA81D05038" modified="2010-01-19" version="1">MTMITTRCPHCKALNQLPAERINEAATCGSCKEQLLDGHPVEGTADNLATLISGEKPVVVDFWAPWCGPCVGFAPVFKDVAEEREGDVRFVKVDTEAQQELAMQYRIRSIPTIMVFKNGQMVDVINGALPKTHFNEWLDQALEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4B1</accession>
    <name>D0Z4B1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Precorrin-2 dehydrogenase</fullName>
            <ecNumber evidence="3">1.3.1.76</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_000367</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>NAD(+) + precorrin-2 = 2 H(+) + NADH + sirohydrochlorin</text>
            <dbReference type="Rhea" id="RHEA:15613"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58351"/>
            <dbReference type="ChEBI" id="CHEBI:58827"/>
            <dbReference type="EC" id="1.3.1.76"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Porphyrin-containing compound metabolism; siroheme biosynthesis; sirohydrochlorin from precorrin-2: step 1/1.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.76" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304168.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000367"/>
    <dbReference type="EnsemblBacteria" id="EEZ39349">
        <property type="protein sequence ID" value="EEZ39349"/>
        <property type="gene ID" value="VDA_000367"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1648">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1185397at2"/>
    <dbReference type="UniPathway" id="UPA00262">
        <property type="reaction ID" value="UER00222"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004325">
        <property type="term" value="F:ferrochelatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043115">
        <property type="term" value="F:precorrin-2 dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019354">
        <property type="term" value="P:siroheme biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028161">
        <property type="entry name" value="Met8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037115">
        <property type="entry name" value="Sirohaem_synt_dimer_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028281">
        <property type="entry name" value="Sirohaem_synthase_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019478">
        <property type="entry name" value="Sirohaem_synthase_dimer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006367">
        <property type="entry name" value="Sirohaem_synthase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35330">
        <property type="entry name" value="PTHR35330"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10414">
        <property type="entry name" value="CysG_dimeriser"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14824">
        <property type="entry name" value="Sirohm_synth_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="SSF53790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01470">
        <property type="entry name" value="cysG_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="4 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sirohm_synth_M" evidence="8">
        <location>
            <begin position="119"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="CysG_dimeriser" evidence="7">
        <location>
            <begin position="151"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF10414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF14824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ39349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="315" mass="35988" checksum="DF9D004AF66DEB67" modified="2010-01-19" version="1">MDFFPVFLRLDDRQVLVVGGGEVACRKVDLLLKAQANITLVSPQLHPYLQQLVANGRLTYRQKCYQTEDLIGFDQVWATTNQQALNQQIHSDATQRSLWVNVIDNPPLCHFITPSMVDRSPIQIAISSGGASPVLVRYLREKIETVLPQNLSLIANYAGMQRTRIKQHFATVDERRKFWEKFFNLTAVDIATTEEELESAFVNLLQNNTQQEQHITVVHVGQDPELLTLKALRLMQQAELVLFATTTPDIFIDLCRRDADRQSFIDGHDLVKLLDNREKSQRICLLTPDKTVIEQLQHNPTYSTRLLLVSAIDNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-12-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4F8</accession>
    <name>D0Z4F8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative alpha-1,2-mannosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000414</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304303.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000414"/>
    <dbReference type="EnsemblBacteria" id="EEZ39396">
        <property type="protein sequence ID" value="EEZ39396"/>
        <property type="gene ID" value="VDA_000414"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3537">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="100818at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005887">
        <property type="entry name" value="Alpha_mannosidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041371">
        <property type="entry name" value="GH92_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012939">
        <property type="entry name" value="Glyco_hydro_92"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07971">
        <property type="entry name" value="Glyco_hydro_92"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17678">
        <property type="entry name" value="Glyco_hydro_92N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01180">
        <property type="entry name" value="aman2_put"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro_92N" evidence="2">
        <location>
            <begin position="45"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_92" evidence="1">
        <location>
            <begin position="284"/>
            <end position="809"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="820" mass="92314" checksum="8215CFFF03043628" modified="2010-01-19" version="1">MYKNKITPLSLAIAIGLGLVGCNSDSDNNSIGKVSPPVPTELIQYVNPFIGTGADGHTFPGAVYPAGMVQLSPDTEMDGWGSAAGYFDHGKQEDIPVYGFSHTHLSGTGITDLGDILVLPFTDKSNATYNTFDKQNEVAEAGYYAVELNRGEIKAELTTSPRVGYHKYTFAADQTPFIKFDLDHTLNKSWGNRTTIGNIEFIDPYTIRGMRSSDGWANNQHIYFYAKFNQPIVKATAMIDGVETEIKLQDDAFEAVKSIAYLEFAKTEQPIEIKVGISPTSTEGAQNNLTTEVPEWSFANTKNKAQQAWHDELAKVEVKGGTEDQKEIFYTAMYHAQIAPMIFQDVDGTYRAMRTQELKEAGDTPNYSIYSMWDTFRAFHPLQTIINPEKAQQYANDLIRKYQDGGILPKWELHGHYTGTMIGFPAVSIIADAMVKGLDIDPQDAKEASEFTVRYHEKEMFPDWTEDQNIGAANVVQVKVYEENGFVHHGYWNSASYTLEFAYGDWAMAEIARMAGDVRLQDEFLARSDNWLNHWDAETGFLRPKNHPNSSSPNKPPLAFNQPVDETRMDECVDVEWPQGSGDMKQQCPLLPFDPYYVDEFAFTEGNAWQWKFQPMHDFDRLKQEIYQADLAKGKETTPEKAFREDLDELFTARSSNTGEELPDLTGYIGQYMHGNEPSHHIPYLYSQTDEPWKAQEYLDRIMNEFYTTEPTGLIGNEDVGQMSSWYILSALGFYQVTPADPTYTIGRPLFDEVSIEVKGGEFKIIADNNSPVNKYVKSVTINGKPLDNTFGFEHSEIKAGGILHFVMTGDKNEAMKAAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4I2</accession>
    <name>D0Z4I2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Hypothetical sigma-54 dependent transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_000440</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304372.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000440"/>
    <dbReference type="EnsemblBacteria" id="EEZ39420">
        <property type="protein sequence ID" value="EEZ39420"/>
        <property type="gene ID" value="VDA_000440"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2204">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="123059at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002197">
        <property type="entry name" value="HTH_Fis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045343">
        <property type="entry name" value="VpsR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02954">
        <property type="entry name" value="HTH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14532">
        <property type="entry name" value="Sigma54_activ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20161">
        <property type="entry name" value="VpsR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50045">
        <property type="entry name" value="SIGMA54_INTERACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="5">
        <location>
            <begin position="147"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ39420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="446" mass="51438" checksum="6942E7D0CFD81F7D" modified="2010-01-19" version="1">MIVNHQANVKKVNKKVVILSSSNDSWVLLLERNNYDVVRCKDIRELDAILEDETNCICIADLTNCVFSLACITTKAMNNQHVRWVTILNKEQLDVDVVRSFIGKFCSDYFLSPIVDGQFMPFIKHQMGMTKITNNKNPKDVLIKLLLSGESKKVKRLKDLVRRVSSSDVNIFITGENGTKKQSLARYLWHSSGRKYGRFFTIDCDLLLTSSTQRDIFYHYFSNSAKNIENFKNETVYLKNLQSLPQDFQLKLLEFFNLDLKSRLRLETQNDIKIISSSSIQPDTLLNEYQFNKELFYKLNIFHLDVPSLRERSEDIRKFAQYFLDIHLNKINTMAVKFSEDIDKLLLSYPWPNNLIELENQVKQAVISSEGPVITSDAFLLPSTKCAKRSLKSIKDEAEKDILLSALHLHHGQVMSAAKDLGISRATMYRLLSKHQILPDGDRIRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4I9</accession>
    <name>D0Z4I9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Hypothetical membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_000447</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EamA transporter family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304390.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39427">
        <property type="protein sequence ID" value="EEZ39427"/>
        <property type="gene ID" value="VDA_000447"/>
    </dbReference>
    <dbReference type="GeneID" id="57342613"/>
    <dbReference type="eggNOG" id="COG2962">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1391352at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004626">
        <property type="entry name" value="RarD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22911:SF114">
        <property type="entry name" value="PTHR22911:SF114"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00688">
        <property type="entry name" value="rarD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="98"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="150"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="178"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="215"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="246"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="270"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="9">
        <location>
            <begin position="7"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ39427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="302" mass="33393" checksum="63A934C96B9572B1" modified="2010-01-19" version="1">MQSSRAGNALAAFSFILWGILPLYYQYLPQADINELLALRIIFSVPFMLIAMLLLGKKLPSLSELLADKKSLIMCCIAGIVMCVSWYAFTWAMTHGQVLAASLGYFINPLFAISLGVIFLKEKLSPAQLAAVVLAAAGISFQVWSYGTLPWLALVMGSFFAIYGLTKKYIKYDALTSVTLEAVVLTPFAVIYMIYDYMSGSSVALTSGMSTFWLYVGSAPVTLAPLIFFALAINRTSLTMVGLMQYIEPTLQLLLAVFLFGEIFDHTKAVSFGFIWLGLILCGVEAMARYYKKKKRPPMQML</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4J5</accession>
    <name>D0Z4J5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Glutathione synthetase</fullName>
            <ecNumber evidence="10">6.3.2.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">GSH synthetase</fullName>
            <shortName evidence="10">GSH-S</shortName>
            <shortName evidence="10">GSHase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Glutathione synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">gshB</name>
        <name evidence="13" type="ORF">VDA_000453</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + glutathione + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13557"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:58173"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="10">Sulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the prokaryotic GSH synthase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.3" evidence="10"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000453"/>
    <dbReference type="EnsemblBacteria" id="EEZ39433">
        <property type="protein sequence ID" value="EEZ39433"/>
        <property type="gene ID" value="VDA_000453"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0189">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00142">
        <property type="reaction ID" value="UER00210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004363">
        <property type="term" value="F:glutathione synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00162">
        <property type="entry name" value="GSH_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006284">
        <property type="entry name" value="Glut_synth_pro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004218">
        <property type="entry name" value="GSHS_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004215">
        <property type="entry name" value="GSHS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21621:SF4">
        <property type="entry name" value="PTHR21621:SF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02955">
        <property type="entry name" value="GSH-S_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02951">
        <property type="entry name" value="GSH-S_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 10" id="KW-0317">Glutathione biosynthesis</keyword>
    <keyword evidence="3 10 13" id="KW-0436">Ligase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0464">Manganese</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="12">
        <location>
            <begin position="119"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ39433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="336" mass="37584" checksum="761B527FD1D370BC" modified="2010-01-19" version="1">MYPWDQVEPETDSTLRLIHEAASRGHTVAITTPNNLTMRDSMAIAFCHVLKKGDVSNNIPSFYRKAEFNQAQLPLAGFDTIFMRANPPLDTMALNFLDSVRDDTFIMNDIDGLRVANNKLYTASLPDPNNEFIPVTHVSKNRDYLERVLDESPNDRMILKPLNGYGGKGVILVEKSAKSSVKSLLDFYIGDNKNYVILQDYIEGAEQGDVRIMMLNGEPIGAMRRVPAQGDVRSNIHAGGREVKHTLTKQEIRLCKHIGPKLVRDGLYFVGLDVINGKLVEVNVLSPGGITRINRLNRARLQADVLDFVESVVRAKEVSIARKTAFRKVIEDASTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4N6</accession>
    <name>D0Z4N6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000494</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304518.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000494"/>
    <dbReference type="EnsemblBacteria" id="EEZ39474">
        <property type="protein sequence ID" value="EEZ39474"/>
        <property type="gene ID" value="VDA_000494"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1591366at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="7"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="301" mass="34904" checksum="CFA1D15FB14DADD6" modified="2010-01-19" version="1">MPLSKKVDLNLLRVFVSAYQTQSVTKTAEQLDLTQSAVSNALNRLRDNLGNELFTRTGRGIKATRFAQELFQQIEPSYLTLETVLQGLHKFDPIESYRTFSVYCNEAIFHSLRQRLDTTIHDTNISVVLQELPPNEELIYEDLRLEKVDLVIDIAAPNSSQFQSQVVQQDHLCCVVSQQHPRITEDQVTKEQYLLERHAIMNMRRFNLLFIDWLVSDVLPPRKIYSEHNSLLSMLSALTYSDAVAVVPESIAVQYKDIFKLRMISFPFETKSFDSHLIWLKKMETNPANTWLRQLITDIIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4R1</accession>
    <name>D0Z4R1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Carbamate kinase</fullName>
            <ecNumber evidence="3">2.7.2.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000519</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the carbamate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.2" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000519"/>
    <dbReference type="EnsemblBacteria" id="EEZ39499">
        <property type="protein sequence ID" value="EEZ39499"/>
        <property type="gene ID" value="VDA_000519"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0549">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008804">
        <property type="term" value="F:carbamate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006525">
        <property type="term" value="P:arginine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003964">
        <property type="entry name" value="Carb_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30409">
        <property type="entry name" value="PTHR30409"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AA_kinase" evidence="2">
        <location>
            <begin position="18"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="170" mass="18305" checksum="E170CC00410D7A76" modified="2010-01-19" version="1">MQTSDKIFKEDGQYYRRVVPSPKPTDIVELKQIETLVKADNVVIACGGGGVPVCFENGTSSGVECVIDKDLTAELLAEKINADLFIILTDGSVYKNYGKEDQAEMRRATPAGLSEFNFPAGSMGPKIDAVCQFVNSGRGNAAIGSLFELDKIIVNEAGTLITQGEGIIYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4S0</accession>
    <name>D0Z4S0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminopyrimidine aminohydrolase</fullName>
            <ecNumber evidence="1">3.5.99.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000528</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>4-amino-5-aminomethyl-2-methylpyrimidine + H2O = 4-amino-5-hydroxymethyl-2-methylpyrimidine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:31799"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16892"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:63416"/>
            <dbReference type="EC" id="3.5.99.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + thiamine = 4-amino-5-hydroxymethyl-2-methylpyrimidine + 5-(2-hydroxyethyl)-4-methylthiazole + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17509"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16892"/>
            <dbReference type="ChEBI" id="CHEBI:17957"/>
            <dbReference type="ChEBI" id="CHEBI:18385"/>
            <dbReference type="EC" id="3.5.99.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; thiamine diphosphate biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TenA family.</text>
    </comment>
    <dbReference type="EC" id="3.5.99.2" evidence="1"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304634.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000528"/>
    <dbReference type="EnsemblBacteria" id="EEZ39508">
        <property type="protein sequence ID" value="EEZ39508"/>
        <property type="gene ID" value="VDA_000528"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0819">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1537025at2"/>
    <dbReference type="UniPathway" id="UPA00060"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050334">
        <property type="term" value="F:thiaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.910.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016084">
        <property type="entry name" value="Haem_Oase-like_multi-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004305">
        <property type="entry name" value="Thiaminase-2/PQQC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027574">
        <property type="entry name" value="Thiaminase_II"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03070">
        <property type="entry name" value="TENA_THI-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48613">
        <property type="entry name" value="SSF48613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04306">
        <property type="entry name" value="salvage_TenA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0784">Thiamine biosynthesis</keyword>
    <feature type="domain" description="TENA_THI-4" evidence="2">
        <location>
            <begin position="11"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="219" mass="24882" checksum="E66ED738F5BEB3F1" modified="2010-01-19" version="1">MNYQDLITACQQDWNCYTQHNFVTQLAAGTLPHQAYLHYLKQDFLFLKHYARAYALAIYKADNLADMKQTLPGLQALIEHEMDHHVSYCGQWGLTASTMENEPEDVGTVAYTRYVLETGLRGDLIDLFVALAPCAIGYAEIGEHLMSSPTTNKTHNPYLDWIELYGGAIFQQGGNKSRQRLNDQLKDIALDSPKGQRLCQIFKTATRMEVGFWQQALDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4S4</accession>
    <name>D0Z4S4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Phosphomethylpyrimidine kinase</fullName>
            <ecNumber evidence="5">2.7.4.7</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_000532</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + ATP = 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + ADP</text>
            <dbReference type="Rhea" id="RHEA:19893"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:58354"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.7"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>4-amino-5-hydroxymethyl-2-methylpyrimidine + ATP = 4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23096"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16892"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58354"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.49"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cofactor biosynthesis; thiamine diphosphate biosynthesis; 4-amino-2-methyl-5-diphosphomethylpyrimidine from 5-amino-1-(5-phospho-D-ribosyl)imidazole: step 3/3.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.7" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000532"/>
    <dbReference type="EnsemblBacteria" id="EEZ39512">
        <property type="protein sequence ID" value="EEZ39512"/>
        <property type="gene ID" value="VDA_000532"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0351">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="461201at2"/>
    <dbReference type="UniPathway" id="UPA00060">
        <property type="reaction ID" value="UER00138"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008902">
        <property type="term" value="F:hydroxymethylpyrimidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008972">
        <property type="term" value="F:phosphomethylpyrimidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01169">
        <property type="entry name" value="HMPP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045029">
        <property type="entry name" value="HMP/HMP-P_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004399">
        <property type="entry name" value="HMP/HMP-P_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013749">
        <property type="entry name" value="PM/HMP-P_kinase-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20858">
        <property type="entry name" value="PTHR20858"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08543">
        <property type="entry name" value="Phos_pyr_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00097">
        <property type="entry name" value="HMP-P_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phos_pyr_kin" evidence="4">
        <location>
            <begin position="20"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="277" mass="29273" checksum="7DEBE6774A05A316" modified="2010-01-19" version="1">MNNQAVPSKTPITLTIAGSDSGGGAGIQADIKAISATGGYACSVITALTAQNTQGVHSIYSIPANFVAEQLDAVFQDLDIKAVKIGMLSDSNIISIIAHKLRQYQPKYLVVDPVMVATSGDLLLEHNAISTLKEQLLPLANVITPNLPEAAALLDCAQPKTEEDMEAMIEQLRQLGAHSVLLKGGHLGNTTNSTDLLILPHDVLRFTTPRIDTPNTHGTGCTLSAAIASYLAQGYSLTEAVKAAKHYISNAIAHADELQIGSGHGPVHHFFNLANNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4T8</accession>
    <name>D0Z4T8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000171</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000171"/>
    <dbReference type="EnsemblBacteria" id="EEZ39155">
        <property type="protein sequence ID" value="EEZ39155"/>
        <property type="gene ID" value="VDA_000171"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0582">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007069">
        <property type="entry name" value="Transposase_32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026889">
        <property type="entry name" value="Zn_Tnp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04986">
        <property type="entry name" value="Y2_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14319">
        <property type="entry name" value="Zn_Tnp_IS91"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn_Tnp_IS91" evidence="1">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="364" mass="42755" checksum="9D6A7A5D3C6937AB" modified="2010-01-19" version="1">MLACGTSKVGSKHYECENPSCEHRKVIYNSCKSKACSSCGVMLTEKWIAKQLSILPKCEYQHMTLTMPDKLWPIFRLNPWLINLLYRCAVSAFLSFAKKRGIEIGLFCVVHTFGRQLNWNVHFHLSVTRGGVNLKTKRWGNIYFNAAMVEQHWKQQVVSFLRDHYNALNTKHDNYQHIRDFRGWSQFLSSQYSRKWRIHLAKKAEDVGPTVRYLGRYFKRPPIAASRLRHYQGGDVHFVYKDHRDNCYKTLVLSQIEMIDRLVSHISAEKNFRAIRYYGFLSNRKRGEALPLVYDLLDQEEPVEPKPLNYAQMMHHLVGIDPYKCILCGGRMCFVKMEMGLKGHELVALRKAMIREKRRLRYSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4T9</accession>
    <name>D0Z4T9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Resolvase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_000172</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306506.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000172"/>
    <dbReference type="EnsemblBacteria" id="EEZ39156">
        <property type="protein sequence ID" value="EEZ39156"/>
        <property type="gene ID" value="VDA_000172"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1961">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1791095at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000150">
        <property type="term" value="F:DNA strand exchange activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006118">
        <property type="entry name" value="Recombinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006119">
        <property type="entry name" value="Resolv_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036162">
        <property type="entry name" value="Resolvase-like_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00239">
        <property type="entry name" value="Resolvase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00857">
        <property type="entry name" value="Resolvase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53041">
        <property type="entry name" value="SSF53041"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00398">
        <property type="entry name" value="RECOMBINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51736">
        <property type="entry name" value="RECOMBINASES_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0229">DNA integration</keyword>
    <keyword evidence="3" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Resolvase/invertase-type recombinase catalytic" evidence="5">
        <location>
            <begin position="1"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-serine intermediate" evidence="4">
        <location>
            <position position="9"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR606118-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ39156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="203" mass="22167" checksum="EC3D45DD6B1288F3" modified="2010-01-19" version="1">MRIGYARISKSDGSQVLDLQQDALLAAGVSQESIYKDEISGKSDKRPGLDSCLKALRPGDVLIVWKLDRLGRSLKHLVNTIDDLADRQIGFKVLTGQGAEIDTTTASGKLVFGIFAALAEFERELISERTKAGLAAARARGREGGRSFKLTKSQVRLAQASMKSRDCSVSELCKELGISRQALYKYVGPDGEIREHGKRVLES</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4W8</accession>
    <name>D0Z4W8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Type III secretion protein SpaR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_000201</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 8">Cell membrane</location>
            <topology evidence="2 8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the FliR/MopE/SpaR family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306589.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000201"/>
    <dbReference type="EnsemblBacteria" id="EEZ39185">
        <property type="protein sequence ID" value="EEZ39185"/>
        <property type="gene ID" value="VDA_000201"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4791">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1942709at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002010">
        <property type="entry name" value="T3SS_IM_R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006304">
        <property type="entry name" value="T3SS_SpaR/YscT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30065">
        <property type="entry name" value="PTHR30065"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01311">
        <property type="entry name" value="Bac_export_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00953">
        <property type="entry name" value="TYPE3IMRPROT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01401">
        <property type="entry name" value="fliR_like_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="78"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="123"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="181"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="218"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ39185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="260" mass="29000" checksum="2E6D7C61D781EEF8" modified="2010-01-19" version="1">MSYDDLHQALFLYSLTLPRLMACFIFLPILNKQTLGGTLVRNGVLCSLALFIFPMINQQDLPAETDGIWLMVILGKEVLLGMLIGFVAAIPFWAIEAAGFLVDNQRGAAMASMFNPTLGSQSTPTAVLLTQTLITLFFSGGGFVTFIYALFNSYSSWPVISFFPTVTEEWVHFFYAQFEQLMWLGVLMSAPLVLAMFLAEFGLALISRFAPQLNVFSLAMPIKSAIASVLLIVYLALMMDHFQALFSDIVLFREQLNTIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4X5</accession>
    <name>D0Z4X5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Type III secretion thermoregulatory protein (LcrF,VirF,transcription regulation of virulence plasmid)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000208</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306609.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000208"/>
    <dbReference type="EnsemblBacteria" id="EEZ39192">
        <property type="protein sequence ID" value="EEZ39192"/>
        <property type="gene ID" value="VDA_000208"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1268974at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020449">
        <property type="entry name" value="Tscrpt_reg_HTH_AraC-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00032">
        <property type="entry name" value="HTHARAC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="2">
        <location>
            <begin position="180"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="293" mass="34050" checksum="BBFE62A2E2BB5002" modified="2010-01-19" version="1">MDVLGQLNTERVNSLSRKIHSTCYYEKYDEVFHSRQSHIVVVHNGQLQVQTGDCTLDVVAGCGVFLYQGDYLLEYTPVDGQYTASVIEFDNELVSQFLQKHSDLLMSLPKVDNVQSGLFPFTFNLLIEQTLSGMKTLEEQSYPDTIMRLKYEEMLILLLHGEQGENLYALLSQLTNKTSDRLRRFMELHYLKEWKLTDYAQEFGASLTTFKELFNEHYGVSPRAWISERRLLYAHKLLLTSKMSIVDVAMEAGFSSQSYFTQSYRRRFGTTPSRVRSGMNKWFCRKVRELDNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4Y3</accession>
    <name>D0Z4Y3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000216</name>
        <name evidence="3" type="ORF">VDA_000241</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306631.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39200">
        <property type="protein sequence ID" value="EEZ39200"/>
        <property type="gene ID" value="VDA_000216"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39225">
        <property type="protein sequence ID" value="EEZ39225"/>
        <property type="gene ID" value="VDA_000241"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3547">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="655500at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003346">
        <property type="entry name" value="Transposase_20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002525">
        <property type="entry name" value="Transposase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01548">
        <property type="entry name" value="DEDD_Tnp_IS110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02371">
        <property type="entry name" value="Transposase_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEDD_Tnp_IS110" evidence="1">
        <location>
            <begin position="6"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="343" mass="37838" checksum="1971F99DDBFA67FA" modified="2010-01-19" version="1">MTMVTVGIDLAKNVYQVHGVDSHGKTVLKQKIKRNQLTAFFANKPPCLIGMEACSGAHYWARLLQSQGHSVKLMAPQFVKPYVKTNKNDAADAEAICEAVTRPNMRFVSIKSPEQQSLLSVHRARMGLIKSQTAQINQIRGLLAEFGIVMPTGKIAVFKHIPLILEDADNNLPGTFRAVLAQLYQHLTELREHTETLEKILKEHYKQYALSQRIATLPGIGLLTATAIVGTIGDGTEFKNGRQLSSWLGLVPKQHSSGGRNVLLGISKRGDSYLRTLLIHGARSVICARKNSLSDDGWLGSLIHRRNTNVAAVALANKNARILWALLTKGEEYQANKDCNLYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z505</accession>
    <name>D0Z505_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000238</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000238"/>
    <dbReference type="EnsemblBacteria" id="EEZ39222">
        <property type="protein sequence ID" value="EEZ39222"/>
        <property type="gene ID" value="VDA_000238"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0582">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007069">
        <property type="entry name" value="Transposase_32"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04986">
        <property type="entry name" value="Y2_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="208" mass="24701" checksum="EEA78E41B8F921A9" modified="2010-01-19" version="1">MVSFLRDHYNALNTKHDNYQHIRDFRGWSQFLSSQYSRKWRIHLAKKTEDVGPTVRYLGRYFKRPPIAASRLRHYQGGDVHFVYKDHRDNCYKTLILSQIEMIDRLASHIPAEKNFRAIRYYGFLSNIKRGEALPLVYDLLDQEEPVEPKPLNYAQMMHHLVGIDPYKCILCGGRVCFVKMEMGLKGHELVALRKAMIREKRRLRYSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z577</accession>
    <name>D0Z577_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative sex pilus assembly and synthesis protein TraC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000127</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306923.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000127"/>
    <dbReference type="EnsemblBacteria" id="EEZ39111">
        <property type="protein sequence ID" value="EEZ39111"/>
        <property type="gene ID" value="VDA_000127"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3451">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="182908at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043964">
        <property type="entry name" value="P-loop_TraG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014117">
        <property type="entry name" value="TraC-F-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025955">
        <property type="entry name" value="TraC/Conjuga_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045978">
        <property type="entry name" value="TRAC_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19357">
        <property type="entry name" value="DUF5934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19044">
        <property type="entry name" value="P-loop_TraG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11130">
        <property type="entry name" value="TraC_F_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02746">
        <property type="entry name" value="TraC-F-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5934" evidence="2">
        <location>
            <begin position="311"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="domain" description="P-loop_TraG" evidence="1">
        <location>
            <begin position="452"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="domain" description="P-loop_TraG" evidence="1">
        <location>
            <begin position="602"/>
            <end position="752"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF19044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="861" mass="96852" checksum="D88EB1EA291BFE14" modified="2010-01-19" version="1">MGLLAKGKLSTLFKRAHPDAGHLHNELPYRYYNDDTELFENHQSLGFGKHLSVLGGANDELVDALNDLVMRLPEGKDWDYQFVLTGNNQVGHLIDKNCQEASVRGGIVAELAQNQAIYAHYGARHGFNTRMGSSYRFDLKNYTASFYCTSRAKEETVLDIKTSLEYGFVQAGLDHSPITPPELIDQVSQVLNFNSARNTPSKAAYNEDEHLHTQMLELDSEFLIHKGYVESRCTFDHQVEPAHTRIVNFTLRKLPPEFRLYAFSNCLASLKNAANALRCPFRISCNFRVEPTGKQRMDNEGKIRNLVKWVNSPMGRLLPTASKELAEREELQDAFLRDECKIASMIFTLTLFTDKQRMKGDVASALGVFREAGLSLIENDMVQGQALLASLPFSMLEFYDDCKMSGRARSIKTSNLVNFFPIVAEYKQLNGGVLLPTMRHQINYFHPFRMGTDNYNMAITGTSGSGKSFITQNIANAIFSEGGKVWILDKGDSYKKFTQINNGVYMTAGNIFLNPFSHILDAEQKAGGQLGDGRNDGTQDHPLAILLDDITGLIAAMAAPNTDLDDTLESALSDAILMAWESNKQNTLIDHVQDALFTLSEEREDKRIRDFGYQLNKFCQDGIYGDIFNKRSQLDPNVHLTTIELDGFSDNLLQPVMFALMVSINQAMYLAGSRSVPKMCIIEEAWKLMSGSNRQARAFIDKGYRTARKFGGGFTTVTQGIVDFFASPEATSAYNNSDIKLILRQGDGFDKFIKENPEAFDPMHVNLIKRFPPAGQTGFSCSMLQAGPNITFHRLFVDPWTLSLYSTHPKEYEYCETLLSNGTPLMDAINQTAWHFYGDNMKHFEDIKAQYLLDKQSQEMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5J6</accession>
    <name>D0Z5J6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000014</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000008">
        <property type="protein sequence ID" value="EEZ38988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005307265.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000008.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000014"/>
    <dbReference type="EnsemblBacteria" id="EEZ38988">
        <property type="protein sequence ID" value="EEZ38988"/>
        <property type="gene ID" value="VDA_000014"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502Z9Z1">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="170450at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014121">
        <property type="entry name" value="TraN_Ftype"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06986">
        <property type="entry name" value="TraN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02750">
        <property type="entry name" value="TraN_Ftype"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018890" evidence="1">
        <location>
            <begin position="19"/>
            <end position="604"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ38988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="604" mass="66471" checksum="35BC9E90DAAD545D" modified="2010-01-19" version="1">MNQYLLLVTLLVSHIAAADVIGNRFHQEVPNAKASIQSSLSNPNFKGFNAEGYCKDQACINEMNNPSQSQYLNNDAALIAEGEKQLVTNPNAANITEGFNNRPKHTIDPNDPAYRNAKTYMDNSYNISHGISNKYVDCEGGDICKYVDTKRQCSEPTGQPAYCHSEAYPINVNITNGRHVIPVNGEFGVLPLPQNMNVSQIDLPAIRRVPQTVPGGCESSSRPIPVDIHINGQKVTRVNGTFDVLNLGYSCRLSIAIPATSITFSPHKPLSSILIDFSSEHYFNMIAHGNIIVHTKKENTEMGWRDNCKGIPNQCSQTQEICVEGAGTRYINGVPVYLDCWKKKRTYQCQYPNTCTPLLGKAVTGAPLTCQIDNKGCKTQVLGVCVENSVNLACEERQCEQTNLVCGETMFCLNGDCYFEEQKQNGNFSEAASALAALGEAAASLNADNLRIFTGKPAFCDKKPIGLSDCCADSGWGNDIGLTQCSAEEKGLASAKEKKLTIELGEYCAEKVLGVCIRKKKSYCQFDSKMTRIIQEQGKKQLGLGFGSKKHPDCQGFTPEQLQQVDFSKIDMSEFYGDLEANMELPNMQEIQDRINDKYGDLAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVL4</accession>
    <name>D0YVL4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">Superoxide dismutase</fullName>
            <ecNumber evidence="2 6">1.15.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_001606</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Destroys radicals which are normally produced within the cells and which are toxic to biological systems.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>2 H(+) + 2 superoxide = H2O2 + O2</text>
            <dbReference type="Rhea" id="RHEA:20696"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:18421"/>
            <dbReference type="EC" id="1.15.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the iron/manganese superoxide dismutase family.</text>
    </comment>
    <dbReference type="EC" id="1.15.1.1" evidence="2 6"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298367.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001606"/>
    <dbReference type="EnsemblBacteria" id="EEZ40579">
        <property type="protein sequence ID" value="EEZ40579"/>
        <property type="gene ID" value="VDA_001606"/>
    </dbReference>
    <dbReference type="GeneID" id="57342317"/>
    <dbReference type="eggNOG" id="COG0605">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1440645at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004784">
        <property type="term" value="F:superoxide dismutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.55.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001189">
        <property type="entry name" value="Mn/Fe_SOD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019833">
        <property type="entry name" value="Mn/Fe_SOD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019832">
        <property type="entry name" value="Mn/Fe_SOD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019831">
        <property type="entry name" value="Mn/Fe_SOD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036324">
        <property type="entry name" value="Mn/Fe_SOD_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036314">
        <property type="entry name" value="SOD_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02777">
        <property type="entry name" value="Sod_Fe_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00081">
        <property type="entry name" value="Sod_Fe_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000349">
        <property type="entry name" value="SODismutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01703">
        <property type="entry name" value="MNSODISMTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46609">
        <property type="entry name" value="SSF46609"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54719">
        <property type="entry name" value="SSF54719"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00088">
        <property type="entry name" value="SOD_MN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 6 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sod_Fe_N" evidence="7">
        <location>
            <begin position="3"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="Sod_Fe_C" evidence="8">
        <location>
            <begin position="89"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000349-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ40579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="194" mass="21483" checksum="31E24A3FD1C40917" modified="2010-01-19" version="1">MAFELPALPYAKDALEPHISAETIEYHYGKHHNTYVVKLNGLVEGTDLADKSLEEIIKSSAGGVFNNAAQVWNHTFYWHCLSPNAGGEPTGEVAEAINKAFGSFEAFKAQFTDSAVNNFGSGWTWLVKNTDGTLAIMNTSNAGCPIVEEGITPLLTVDVWEHAYYIDYRNLRPTYMDAFWALVNWDFVAKNLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVL5</accession>
    <name>D0YVL5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Glutaredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_001607</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the glutaredoxin family. Monothiol subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298369.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001607"/>
    <dbReference type="EnsemblBacteria" id="EEZ40580">
        <property type="protein sequence ID" value="EEZ40580"/>
        <property type="gene ID" value="VDA_001607"/>
    </dbReference>
    <dbReference type="GeneID" id="57342316"/>
    <dbReference type="eggNOG" id="COG0278">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2001991at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097573">
        <property type="term" value="F:glutathione oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03028">
        <property type="entry name" value="GRX_PICOT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033658">
        <property type="entry name" value="GRX_PICOT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014434">
        <property type="entry name" value="Monothiol_GRX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004480">
        <property type="entry name" value="Monothiol_GRX-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10293">
        <property type="entry name" value="PTHR10293"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005894">
        <property type="entry name" value="Monothiol_GRX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00365">
        <property type="entry name" value="TIGR00365"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="4 8" id="KW-0408">Iron</keyword>
    <keyword evidence="5 8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutaredoxin" evidence="9">
        <location>
            <begin position="16"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Glutathione binding" evidence="7">
        <location>
            <begin position="83"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="21"/>
        </location>
        <ligand>
            <name>glutathione</name>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="29"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>glutathione</name>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>glutathione</name>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR005894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR005894-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR005894-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ40580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="109" mass="12190" checksum="D3EEDA1D9C01D63A" modified="2010-01-19" version="1">METIDKIKQQIAENSILLYMKGSPKLPSCGFSSQAAQALMSCGEKFAYVDILQNPDIRAELPIYAQWPTFPQLWVEGELIGGCDIIIEMFQKGELQPLIKEAAARRDAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVX3</accession>
    <name>D0YVX3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA-modifying protein YgfZ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001254</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the tRNA-modifying YgfZ family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297737.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001254"/>
    <dbReference type="EnsemblBacteria" id="EEZ40232">
        <property type="protein sequence ID" value="EEZ40232"/>
        <property type="gene ID" value="VDA_001254"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0354">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1984573at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005542">
        <property type="term" value="F:folic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009451">
        <property type="term" value="P:RNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01175">
        <property type="entry name" value="tRNA_modifying_YgfZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029043">
        <property type="entry name" value="GcvT/YgfZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023758">
        <property type="entry name" value="tRNA-modifying_YgfZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045179">
        <property type="entry name" value="YgfZ/GcvT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017703">
        <property type="entry name" value="YgfZ/GcvT_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22602">
        <property type="entry name" value="PTHR22602"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101790">
        <property type="entry name" value="SSF101790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03317">
        <property type="entry name" value="ygfZ_signature"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4" id="KW-0290">Folate-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0819">tRNA processing</keyword>
    <feature type="binding site" evidence="4">
        <location>
            <position position="29"/>
        </location>
        <ligand>
            <name>folate</name>
            <dbReference type="ChEBI" id="CHEBI:62501"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>folate</name>
            <dbReference type="ChEBI" id="CHEBI:62501"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="323" mass="35671" checksum="012950376ABC6199" modified="2010-01-19" version="1">MSTPFNFSSLALSSQDALPSLAVIDLHDWAAVTLVGQDAKSYLQGQVTCDVVSLPEQESTLGAHCDAKGKMRTIFRLFHHQQGYAYIQRQSVMDSQLPELKKYAVFSKVEIKPSNEVILGIAGSDAQAFIDQHFNGTSNVRHHDQGSAIKIDEQRWQLLISPELAEQLIHALPEKATCCDSTLWDLYDIRAALPRIDSAIELEFIPQALNLQAVDGISFKKGCYVGQETVARAKYRGINKRAMFIVTGHADHAPQAGDSIERQVGENWRSGGTVITGYHFSDNHALALVVLPNDLEPETSLRFASDEIAHWQLATLPYSLADA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVZ2</accession>
    <name>D0YVZ2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">CTP synthase</fullName>
            <ecNumber evidence="9">6.3.4.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Cytidine 5'-triphosphate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Cytidine triphosphate synthetase</fullName>
            <shortName evidence="9">CTP synthetase</shortName>
            <shortName evidence="9">CTPS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">UTP--ammonia ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">pyrG</name>
        <name evidence="12" type="ORF">VDA_001271</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + H2O + L-glutamine + UTP = ADP + CTP + 2 H(+) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:26426"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + NH4(+) + UTP = ADP + CTP + 2 H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:16597"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>H2O + L-glutamine = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="9">Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Pyrimidine metabolism; CTP biosynthesis via de novo pathway; CTP from UDP: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homotetramer.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="9">CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the CTP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.2" evidence="9"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297758.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001271"/>
    <dbReference type="EnsemblBacteria" id="EEZ40249">
        <property type="protein sequence ID" value="EEZ40249"/>
        <property type="gene ID" value="VDA_001271"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0504">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="783657at2"/>
    <dbReference type="UniPathway" id="UPA00159">
        <property type="reaction ID" value="UER00277"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003883">
        <property type="term" value="F:CTP synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044210">
        <property type="term" value="P:'de novo' CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03113">
        <property type="entry name" value="CTPS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01746">
        <property type="entry name" value="GATase1_CTP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01227">
        <property type="entry name" value="PyrG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004468">
        <property type="entry name" value="CTP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017456">
        <property type="entry name" value="CTP_synthase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033828">
        <property type="entry name" value="GATase1_CTP_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11550">
        <property type="entry name" value="PTHR11550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06418">
        <property type="entry name" value="CTP_synth_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00337">
        <property type="entry name" value="PyrG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="4 9 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 9" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CTP_synth_N" evidence="11">
        <location>
            <begin position="5"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="GATase" evidence="10">
        <location>
            <begin position="301"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Amidoligase domain" evidence="9">
        <location>
            <begin position="1"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="L-glutamine binding" evidence="9">
        <location>
            <begin position="380"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; for glutamine hydrolysis" evidence="9">
        <location>
            <position position="379"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="515"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="517"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="14"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="15"/>
            <end position="20"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="72"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="147"/>
            <end position="149"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <note>allosteric inhibitor</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="187"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="223"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="239"/>
            <end position="241"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="352"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="403"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="470"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF06418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ40249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="546" mass="59998" checksum="BD22A12AEACC5C92" modified="2010-01-19" version="1">MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLDVTMMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMTKRNNFTAGRVYADVLRKERRGDYLGATVQVIPHITNEIKSRVIAGAKGHDVAIVEVGGTVGDIESLPFMEAIRQLAVELGRERAMFMHLTLVPYLAAAGEVKTKPTQHSVKELLSIGIQPDVLICRSDRMIPANERAKIALFCNVPEKAVISMKDVDSIYKIPQLIKAQGLDDLVCQRFGITAPEANLAEWEQVIYEEANPTGEVTIGMVGKYIELPDAYKSVNEALKHAGLKNRLSVKIKYIDSQDVESKGTEILEGLDAILVPGGFGNRGVEGKILTAKYARENKIPYLGICLGMQVALIEYARNVAGMTDAHSTEFSQDTTHPVVGLITEWIDNEGNVEERSEKSDLGGTMRLGAQLCHLQDGTKARDLYAQPSIHERHRHRYEVNNSLLPKLEKAGLKVSGLSADKKLVEIIEIPNHPWFVAAQFHPEFTSTPRDGHPLFAGFVKAAGQHQRGELNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWE8</accession>
    <name>D0YWE8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hypothetical SAM-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001396</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297993.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001396"/>
    <dbReference type="EnsemblBacteria" id="EEZ40371">
        <property type="protein sequence ID" value="EEZ40371"/>
        <property type="gene ID" value="VDA_001396"/>
    </dbReference>
    <dbReference type="GeneID" id="57339684"/>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1730305at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="74"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="263" mass="30143" checksum="7A34BA36E0B3565F" modified="2010-01-19" version="1">MKPARTLEHIEPPHSWSDVTNGTWVAELLQTRLDEWSPKLFGYHMLKLGGLSGEVSSQHCSIQHQVCIDKCSDYRTLVADYFQLPFIEKSFDACILLHQLDYCTDPHRLLREIDRVMVDDGYLILSGSNPLSLLGFQGLLPWNRKKNPWLGRMFLPARVQDWLALLNYEVIYHDDFAILPSARHSACAAWLENMIAEPLNAFGSFYFMVARKRTCPLKPIKPTWKLRRHLAPIGVNCRTQVKEMTNELLPQSSLSSDSKEASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWG1</accession>
    <name>D0YWG1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UPF0250 protein VDA_001420</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001420</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the UPF0250 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298032.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001420"/>
    <dbReference type="EnsemblBacteria" id="EEZ40394">
        <property type="protein sequence ID" value="EEZ40394"/>
        <property type="gene ID" value="VDA_001420"/>
    </dbReference>
    <dbReference type="GeneID" id="57339654"/>
    <dbReference type="eggNOG" id="COG2921">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2028648at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00659">
        <property type="entry name" value="UPF0250"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007454">
        <property type="entry name" value="UPF0250"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027471">
        <property type="entry name" value="YbeD-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38036">
        <property type="entry name" value="PTHR38036"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04359">
        <property type="entry name" value="DUF493"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117991">
        <property type="entry name" value="SSF117991"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="90" mass="10156" checksum="ADCC39229099AEF9" modified="2010-01-19" version="1">MQNEQPKLRDLLEFPCKFSYKVMGENKPELADLVVEVIQRHAPGDYLPTVKPSAKGNYSAVSVTINATHIDQVETLYKELAEIDIVRVVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWH4</accession>
    <name>D0YWH4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Apolipoprotein N-acyltransferase</fullName>
            <shortName evidence="9">ALP N-acyltransferase</shortName>
            <ecNumber evidence="9">2.3.1.269</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">lnt</name>
        <name evidence="11" type="ORF">VDA_001433</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a glycerophospholipid + N-terminal S-1,2-diacyl-sn-glyceryl-L-cysteinyl-[lipoprotein] = a 2-acyl-sn-glycero-3-phospholipid + H(+) + N-acyl-S-1,2-diacyl-sn-glyceryl-L-cysteinyl-[lipoprotein]</text>
            <dbReference type="Rhea" id="RHEA:48228"/>
            <dbReference type="Rhea" id="RHEA-COMP:14681"/>
            <dbReference type="Rhea" id="RHEA-COMP:14684"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:136912"/>
            <dbReference type="ChEBI" id="CHEBI:140656"/>
            <dbReference type="ChEBI" id="CHEBI:140657"/>
            <dbReference type="ChEBI" id="CHEBI:140660"/>
            <dbReference type="EC" id="2.3.1.269"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="9">Protein modification; lipoprotein biosynthesis (N-acyl transfer).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.269" evidence="9"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298054.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001433"/>
    <dbReference type="EnsemblBacteria" id="EEZ40407">
        <property type="protein sequence ID" value="EEZ40407"/>
        <property type="gene ID" value="VDA_001433"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0815">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1291198at2"/>
    <dbReference type="UniPathway" id="UPA00666"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016410">
        <property type="term" value="F:N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042158">
        <property type="term" value="P:lipoprotein biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07571">
        <property type="entry name" value="ALP_N-acyl_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01148">
        <property type="entry name" value="Lnt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004563">
        <property type="entry name" value="Apolipo_AcylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045378">
        <property type="entry name" value="LNT_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20154">
        <property type="entry name" value="LNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="SSF56317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00546">
        <property type="entry name" value="lnt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="30"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="89"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="161"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="193"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="484"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="domain" description="CN hydrolase" evidence="10">
        <location>
            <begin position="225"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ40407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="517" mass="57856" checksum="858999C34546275B" modified="2010-01-19" version="1">MTTKKLNLLGRLIAAVPAGALATFSFAPYSHWYLAPISLILFFLLLQKQTIKQSTLIGFFWGLGIFGTGISWVHVSIDNFGGMPKIASVFLMTLLISYLALYPAIFANLYHRFFRQKPVLQLLVSGPVLWLLLDWFRGWFLTGFPWLWMGYSQIESPLRTIAPILGVEGITLALVLISGAIVATLYYRAWKTLLIPVIIVASCLALKPIQWVKPDPSRTVSVALIQGNIPQELKWLPSQRWPTLMKYMDLTEQNWDADIIIWPEAAIPALEEQIPTFLENLDKTAREHHTTLLTGVLDQKADGEFFNNILTLGVNPAGPYNYATAHRYSKHHLLPFGEFVPFGDLLRPIAPFFNLPMSSFSRGAYIQPNLQAHGLSIAPALCYEVAFSEQVRENVHPNTELLLTLSNDAWFGRSIGPFQHMEIAQMRSLELGKPLLRATNTGITAVVDADGNITKKIPQFETAVLRDKVVPTLGTTPYGHMGSWPLYVYCALISVIALLFGRKYSQKKAAKVTTEAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWI2</accession>
    <name>D0YWI2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA (guanine-N(7)-)-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">tRNA (guanine(46)-N(7))-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">tRNA(m7G46)-methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">trmB</name>
        <name evidence="2" type="ORF">VDA_001224</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>guanosine(46) in tRNA + S-adenosyl-L-methionine = N(7)-methylguanosine(46) in tRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42708"/>
            <dbReference type="Rhea" id="RHEA-COMP:10188"/>
            <dbReference type="Rhea" id="RHEA-COMP:10189"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74480"/>
            <dbReference type="EC" id="2.1.1.33"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">tRNA modification; N(7)-methylguanine-tRNA biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.33" evidence="1"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297673.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001224"/>
    <dbReference type="EnsemblBacteria" id="EEZ40202">
        <property type="protein sequence ID" value="EEZ40202"/>
        <property type="gene ID" value="VDA_001224"/>
    </dbReference>
    <dbReference type="GeneID" id="57339900"/>
    <dbReference type="eggNOG" id="COG0220">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1025521at2"/>
    <dbReference type="UniPathway" id="UPA00989"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008176">
        <property type="term" value="F:tRNA (guanine-N7-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01057">
        <property type="entry name" value="tRNA_methyltr_TrmB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003358">
        <property type="entry name" value="tRNA_(Gua-N-7)_MeTrfase_Trmb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23417">
        <property type="entry name" value="PTHR23417"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02390">
        <property type="entry name" value="Methyltransf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00091">
        <property type="entry name" value="TIGR00091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51625">
        <property type="entry name" value="SAM_MT_TRMB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="1 2" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="1">
        <location>
            <begin position="223"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="245" mass="27785" checksum="439039FCE3C2B86C" modified="2010-01-19" version="1">MCEDTKKSGEVTMMDLTDDGKVKRKIRSFVRREGRLTKGQEAALENNWSTMGIDFAPELLDLKEVFGREAPVVLEIGFGMGASLVEMAKNAPEKNFIGIEVHSPGVGACLMAAEAEGLTNLRVMCHDAVEVFEHMLPEQSLDTLQLFFPDPWHKARHHKRRIVQPEFAQMIRSKLKIGGIFHMATDWENYAEHMVEVMDAAPGYRNTATDGPYIERPEDRPLTKFEARGHRLGHGVWDMKYARTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWN1</accession>
    <name>D0YWN1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">dTDP-4-dehydrorhamnose 3,5-epimerase</fullName>
            <ecNumber evidence="3 7">5.1.3.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Thymidine diphospho-4-keto-rhamnose 3,5-epimerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_001522</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>dTDP-4-dehydro-6-deoxy-alpha-D-glucose = dTDP-4-dehydro-beta-L-rhamnose</text>
            <dbReference type="Rhea" id="RHEA:16969"/>
            <dbReference type="ChEBI" id="CHEBI:57649"/>
            <dbReference type="ChEBI" id="CHEBI:62830"/>
            <dbReference type="EC" id="5.1.3.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Carbohydrate biosynthesis; dTDP-L-rhamnose biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.13" evidence="3 7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298210.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001522"/>
    <dbReference type="EnsemblBacteria" id="EEZ40496">
        <property type="protein sequence ID" value="EEZ40496"/>
        <property type="gene ID" value="VDA_001522"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1898">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1618609at2"/>
    <dbReference type="UniPathway" id="UPA00124"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008830">
        <property type="term" value="F:dTDP-4-dehydrorhamnose 3,5-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019305">
        <property type="term" value="P:dTDP-rhamnose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000888">
        <property type="entry name" value="dTDP_sugar_isom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21047">
        <property type="entry name" value="PTHR21047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00908">
        <property type="entry name" value="dTDP_sugar_isom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01221">
        <property type="entry name" value="rmlC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="132"/>
        </location>
    </feature>
    <feature type="site" description="Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose" evidence="6">
        <location>
            <position position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR600888-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR600888-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ40496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="181" mass="20603" checksum="D9D7AA0017282ACD" modified="2010-01-19" version="1">MNVIETDIPDVKIIEPTVFGDERGFFMETWNQKKFEELVTGKPTQFVQDNHSKSKKGILRGLHYQTENTQGKLVRVVSGEVFDVAVDIRKNSPTFGKWVGVYLSAENKRQLWVPEGFAHGFYVTSDEAEFVYKCTDFYNPKAEHSILWNDLDIGIEWPLDNAPVLSDKDSKGTLLTKISGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWP3</accession>
    <name>D0YWP3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC</fullName>
            <shortName evidence="5">tRNA mnm(5)s(2)U biosynthesis bifunctional protein</shortName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="5">tRNA (mnm(5)s(2)U34)-methyltransferase</fullName>
                <ecNumber evidence="5">2.1.1.61</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="5">FAD-dependent cmnm(5)s(2)U34 oxidoreductase</fullName>
                <ecNumber evidence="5">1.5.-.-</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="5" type="primary">mnmC</name>
        <name evidence="9" type="ORF">VDA_001529</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>5-aminomethyl-2-thiouridine(34) in tRNA + S-adenosyl-L-methionine = 5-methylaminomethyl-2-thiouridine(34) in tRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:19569"/>
            <dbReference type="Rhea" id="RHEA-COMP:10195"/>
            <dbReference type="Rhea" id="RHEA-COMP:10197"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74454"/>
            <dbReference type="ChEBI" id="CHEBI:74455"/>
            <dbReference type="EC" id="2.1.1.61"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">In the C-terminal section; belongs to the DAO family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.61" evidence="5"/>
    <dbReference type="EC" id="1.5.-.-" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298223.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001529"/>
    <dbReference type="EnsemblBacteria" id="EEZ40503">
        <property type="protein sequence ID" value="EEZ40503"/>
        <property type="gene ID" value="VDA_001529"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0665">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4121">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="912110at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016645">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-NH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004808">
        <property type="term" value="F:tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002097">
        <property type="term" value="P:tRNA wobble base modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01102">
        <property type="entry name" value="MnmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008471">
        <property type="entry name" value="MnmC-like_methylTransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023032">
        <property type="entry name" value="tRNA_MAMT_biosynth_bifunc_MnmC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017610">
        <property type="entry name" value="tRNA_S-uridine_synth_MnmC_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05430">
        <property type="entry name" value="Methyltransf_30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03197">
        <property type="entry name" value="MnmC_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0274">FAD</keyword>
    <keyword evidence="1 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4 5" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Methyltransf_30" evidence="8">
        <location>
            <begin position="125"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="DAO" evidence="7">
        <location>
            <begin position="280"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="region of interest" description="tRNA (mnm(5)s(2)U34)-methyltransferase" evidence="5">
        <location>
            <begin position="1"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="FAD-dependent cmnm(5)s(2)U34 oxidoreductase" evidence="5">
        <location>
            <begin position="284"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="377"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="378"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF05430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ40503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="766" mass="84841" checksum="4C5D2C2900EA0658" modified="2010-01-19" version="1">MSTQDTNQHPAKIENAILDWNELGTPVSNDFDDVYFSNANGLEETRYVFLQQNGLPDRWNDFSRRRFVVAETGFGTGLNFLALWQQFKAFRAENPDATVKELHFISFEKFPVTLEDLKKAHLSWPELSDLAQQLHAHYPPAVADCHRIILEDGLITLDLWFGDIQDCMPQVWTGDEGIVDAWFLDGFAPSKNLAMWNLDVYKGMRNLARSGCTLATFTAAGFVRRELIEAGFEMKKAKGFGHKREMLTGTIGERSAPSNTKPWYHISARAENDSTQALNDIAIIGGGVASAATALSLVRRGQTVTLYCKDEKPAQGASGNKQGAVYPLLNGNHNALSRFFAPAFVFARQFVEQAAQNSQFDHDWCGVVQLGFGEKMGEEGNIGREGKEGKKGGEGREGKAGTEGKEGEDTSLLVSSDESKERQEEEREGSEGKTGREGNKGEEGIKGGEKGADMRNKQRIKLDKMLAGGFPNELICALDHQQTCEVTGVETGFDGVNYPLGGWLCPKELTRALIEQAQATGLLTLHTQSEVCKLQQESDQRWQLQFSDGQSKQHACVVIANGHRFTDFEQTAKIPAYSVRGQVSHIPTNEQLGKLKTVLCYDGYLTPENPHSHTHCIGASYDRNSVDLAFSEQNQHDNKQRLIDCLPQAEWAKSVDVSDNQARVGVRCATRDHLPFMGNVCRYDELLTQYENLKEMQASADKIPVYNNLFALIGLGSRGLSSAPLVGEMMASQICGDPLPMPLSVLEALHPGRMWVRKLVKGRKGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWS6</accession>
    <name>D0YWS6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Phosphoglycerate transport system transcription regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_001471</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298121.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001471"/>
    <dbReference type="EnsemblBacteria" id="EEZ40445">
        <property type="protein sequence ID" value="EEZ40445"/>
        <property type="gene ID" value="VDA_001471"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2204">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="123059at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002197">
        <property type="entry name" value="HTH_Fis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02954">
        <property type="entry name" value="HTH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14532">
        <property type="entry name" value="Sigma54_activ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50045">
        <property type="entry name" value="SIGMA54_INTERACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Response regulatory" evidence="7">
        <location>
            <begin position="8"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="6">
        <location>
            <begin position="143"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="5">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ40445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="425" mass="47897" checksum="3B89E5238EA4D466" modified="2010-01-19" version="1">MLMSDDIQVLVVDDDNDVLDAYQDMLEIAGFEVKTTSDPTQVVTMINRNWPGVVVTDMYMPGLSGIDLLKQLHQQDKELPVIIITGHGDIPMAVDAVRQGATDFLEKPLQPMALITLLEKFIPQRRQVIEQRKTLEFAANDTLLGDSPLIAKIRDQIANAASTRKDVLIEGETGSGRHSVAKLLHKNSDVAEGPLLEVNGSSITNAMEMQHHINQARGGSLILTNPHFMPIEIQQWLCRTLLEQERLGKKETRVLAIVEGLAEPFVEKEEFVPELFYFLSQVRFSLPTLRQRACDITPLFKHFLKLSCLKLNKPIPTVDKAYINTLNRHEWSGNVLELKNVAELYAIGIVKLAGQERSQPLEQMSSPLDDLIDGYEKQVIEDALYLFAGRINDVSAYLQIPRKKLYLRMKKHGLDKAEYKAHSAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWU1</accession>
    <name>D0YWU1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PTS system fructose-specific IIB component</fullName>
            <ecNumber evidence="3">2.7.1.69</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001487</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.1.69" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298143.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001487"/>
    <dbReference type="EnsemblBacteria" id="EEZ40461">
        <property type="protein sequence ID" value="EEZ40461"/>
        <property type="gene ID" value="VDA_001487"/>
    </dbReference>
    <dbReference type="GeneID" id="57342458"/>
    <dbReference type="eggNOG" id="COG1445">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2011067at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103111">
        <property type="term" value="F:D-glucosamine PTS permease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022877">
        <property type="term" value="F:protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05569">
        <property type="entry name" value="PTS_IIB_fructose"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036095">
        <property type="entry name" value="PTS_EIIB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013011">
        <property type="entry name" value="PTS_EIIB_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003501">
        <property type="entry name" value="PTS_EIIB_2/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003353">
        <property type="entry name" value="PTS_IIB_fruc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02302">
        <property type="entry name" value="PTS_IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52794">
        <property type="entry name" value="SSF52794"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00829">
        <property type="entry name" value="FRU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51099">
        <property type="entry name" value="PTS_EIIB_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PTS EIIB type-2" evidence="2">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="102" mass="10946" checksum="66784468C51BB3D9" modified="2010-01-19" version="1">MKIVAVTACPTGIAHTYMAADALNKTAHAMGIQIQVETQGAMGIENQLSLQDIARADVVLIASDIEVEHRARFTGSKIHCVTIEEVLVDAKAVLERCLELCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXI2</accession>
    <name>D0YXI2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">3-oxoacyl-[acyl-carrier-protein] synthase 2</fullName>
            <ecNumber evidence="3 10">2.3.1.179</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">VDA_001688</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>(9Z)-hexadecenoyl-[ACP] + H(+) + malonyl-[ACP] = 3-oxo-(11Z)-octadecenoyl-[ACP] + CO2 + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:55040"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10800"/>
            <dbReference type="Rhea" id="RHEA-COMP:14074"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:83989"/>
            <dbReference type="ChEBI" id="CHEBI:138538"/>
            <dbReference type="EC" id="2.3.1.179"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a fatty acyl-[ACP] + H(+) + malonyl-[ACP] = a 3-oxoacyl-[ACP] + CO2 + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:22836"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:14125"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:138651"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10 12">Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.179" evidence="3 10"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298517.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001688"/>
    <dbReference type="EnsemblBacteria" id="EEZ40659">
        <property type="protein sequence ID" value="EEZ40659"/>
        <property type="gene ID" value="VDA_001688"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="606297at2"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00834">
        <property type="entry name" value="KAS_I_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017568">
        <property type="entry name" value="3-oxoacyl-ACP_synth-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000794">
        <property type="entry name" value="Beta-ketoacyl_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11712">
        <property type="entry name" value="PTHR11712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000447">
        <property type="entry name" value="KAS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03150">
        <property type="entry name" value="fabF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="B_KETOACYL_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10 14" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8 10" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5 10" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 12 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PKS_KS" evidence="13">
        <location>
            <begin position="6"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR000447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000447-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEZ40659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="412" mass="42600" checksum="92B9DF3A32BB1B2C" modified="2010-01-19" version="1">MSKRRVVVTGMGMLTPVGNTVEDSWKALLSGTSGISTIEHFDVTGFATQFAGMVKDFNCEDYMSKKDARKMDLFIQYGIAAGVQALKDSGIEVTDENAARIGVAIGSGIGGLGLIEAGHQALMEKGPRKISPFFVPSTIVNMIAGHMSIMFGLRGPNIAISTACTTGLHNIGHAARMIAYGDADAMVAGGAEKASTPLGMGGFAAAKALSTRNDDPQAASRPWDKDRDGFVLGDGAGVMVLEEYEHAKARGAKIYAEIVGFGMSGDAYHMTSPSADGSGGALAMEACLRDAGINADQLGYINAHGTSTPAGDVAETLGIKRAMGSAADKVMVSSTKSMTGHLLGAAGSVEAIITALTLVDQVVPPTINLDNPGEGCDLDYVPGTARDVNLEYALCNSFGFGGTNGSLLFKKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXM7</accession>
    <name>D0YXM7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Tripeptide aminopeptidase</fullName>
            <ecNumber evidence="6">3.4.11.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_001768</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M20B family.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.4" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40736">
        <property type="protein sequence ID" value="EEZ40736"/>
        <property type="gene ID" value="VDA_001768"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2195">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045148">
        <property type="term" value="F:tripeptide aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006518">
        <property type="term" value="P:peptide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001261">
        <property type="entry name" value="ArgE/DapE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010161">
        <property type="entry name" value="Peptidase_M20B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42994:SF1">
        <property type="entry name" value="PTHR42994:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01882">
        <property type="entry name" value="peptidase-T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00758">
        <property type="entry name" value="ARGE_DAPE_CPG2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00759">
        <property type="entry name" value="ARGE_DAPE_CPG2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="420" mass="46057" checksum="461A1BDCCC5DF4A7" modified="2010-01-19" version="1">MALIAVIPMDKWVGQMNIQQTLINNFTRYVAVSSQSDASNLAVPSSEGQRELATLLKSELMDMGYHDTELLPNSILIARIPGEASLPKIGFVAHLDTVDVGLSAEIKPQVLHYAGEPLCLNEALGIHISEASHPELAKYRQQDILFSDGTSVLGADNKSAIAILMTLAQELSQQTAVHGDIYFAFVPDEEIGLRGAKQLDLAQFPVDLCYTIDCCERGEVIYETFNAGSAKLTVDGITAHPMSAKNVLVNPNLVVADFISLLNDMGKPEQTAEREGYFWVTDIMGNQNSASAMVAIRDFDLMNYEQRKSYLMSLVDFLQIKHPKAVIELDIQDVYSNIAQAMGVNTQALTRLYQVLEQLEIPAKTIAMRGGTDGSALSVKGLFTPNFFTGAHNFHSAFEFLPISSFVDSYKVARALVLTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXP9</accession>
    <name>D0YXP9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">2-dehydro-3-deoxygluconate kinase</fullName>
            <ecNumber evidence="2">2.7.1.45</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001741</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.1.45" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298607.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001741"/>
    <dbReference type="EnsemblBacteria" id="EEZ40709">
        <property type="protein sequence ID" value="EEZ40709"/>
        <property type="gene ID" value="VDA_001741"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0524">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1604782at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008673">
        <property type="term" value="F:2-dehydro-3-deoxygluconokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="1">
        <location>
            <begin position="20"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="308" mass="35530" checksum="6D6C548665EFF537" modified="2010-01-19" version="1">MRIAVLGECYVELSHYPLCQTIGGDDFHIAVYLARLGQYKHFQIDFASAVGLDPFTQAWKQVCRDEHISLGLTEQRSAQFPHFYYPEYQAKNQIIEHHWQDNTAFSTLFSHSITKLERAIELKQIDVLYLSAFAVSRLDDKSKIILVTLLEALKHQGGKCIFNCYCGHYFWTVKQSQYWVLKILSYADLAFVLYENEHKRWRTIGEGMYHLMRSGCSEIIVSSSAKLVISERMRQLMKSSQSRLYFYRSVGLTKRISNGFIAGYIAGFVKGEMIEYRLSLGREMMKAISAYPYALVPISAMRSVLSND</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXR2</accession>
    <name>D0YXR2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Paraquat-inducible protein B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002075</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299357.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002075"/>
    <dbReference type="EnsemblBacteria" id="EEZ41043">
        <property type="protein sequence ID" value="EEZ41043"/>
        <property type="gene ID" value="VDA_002075"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3008">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="855063at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003399">
        <property type="entry name" value="Mce/MlaD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02470">
        <property type="entry name" value="MlaD"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="domain" description="MlaD" evidence="2">
        <location>
            <begin position="46"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="MlaD" evidence="2">
        <location>
            <begin position="280"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="domain" description="MlaD" evidence="2">
        <location>
            <begin position="397"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="domain" description="MlaD" evidence="2">
        <location>
            <begin position="636"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="domain" description="MlaD" evidence="2">
        <location>
            <begin position="743"/>
            <end position="802"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="874" mass="95191" checksum="FF3E87A6927C0D64" modified="2010-01-19" version="1">MNNQNNPQPQPVEIKRDRGISPLWLLPLLALCLAGWLVYKAVNEAGERIQIHFNNASGLIAGRTTIRYQGLEVGMVRDVSLSKDLKSIYVTADIYPEAAKTLRSNTQFWLVKPKASITGISGLDTLVSGNYIALQPGDGEPTTKFTALESQPSDTPVADGLKVQLRSPTLGSVSIGSQVFYKKIPVGEVYNYTLSGNKKRVIIDLLIYPKYENLVTNKSRFWNVSGMSANIGFNGVDVQFESLSALIAGAIAFDSPDEGKPIEQDHLFRLYPDINTAGRGIAIKIELPDNNNINASGSPIMYRGLQIGQISDLRLDKETNKIIADAAIEPSMSDLLTTGSSLLLEEAEVSLNGVKNIGNLIRGNFLRIIPGKGEPTRKFKAITQDTLQEQQKGSANFTLIADTSHGIKRGTKLNYKGITVGRVTNVTLDENKVKFDVLVLPKFTHLIRSGSRFYIEGGIQANVSNKGLDVSIAPADQLITSAISFTSTGKASIAKSYTLYGNKNLASLADNQRSSAAKLTLFADKLPPVSEGSPILYRNLQVGQILGYALKGDGVTINIEIESQYRHLINQQTVFWNRSGVEVEAGIGGLKLTASPLSTLIKGGIAFDTMDNVSNKEGRAFKLYDSLSAAQNFGLQVTLTAKDARSIATNTPIRYQGVNVGKVVEIVPDFKNESVIIKARLFPNYAQTLAKSGSYFWLVQPKLSLTGTENLDSLLSSYIAVEPGNGRYAQTFKLGSSQKLESGKTLYLEAEERDSIAEGTPLLYRDIQVGQVTHVSLGKLSDRVIIEAQVDKEYSYLVRSNTVFWNTSGVNVTLGLTGAEVKAGTVDSILRGGISFATPEKQPLSPKAHNGKHFLLHKEVNPQWLSWRTAIPKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXT4</accession>
    <name>D0YXT4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cytochrome-c oxidase</fullName>
            <ecNumber evidence="5">7.1.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">VDA_002097</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>4 Fe(II)-[cytochrome c] + 8 H(+)(in) + O2 = 4 Fe(III)-[cytochrome c] + 4 H(+)(out) + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:11436"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="7.1.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
        <text evidence="10">Binds 1 copper ion per subunit, denoted as copper B.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
        <text evidence="10">Binds 2 heme groups per subunit, denoted as high- and low-spin.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Energy metabolism; oxidative phosphorylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the heme-copper respiratory oxidase family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.9" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299425.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002097"/>
    <dbReference type="EnsemblBacteria" id="EEZ41065">
        <property type="protein sequence ID" value="EEZ41065"/>
        <property type="gene ID" value="VDA_002097"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3278">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="665754at2"/>
    <dbReference type="UniPathway" id="UPA00705"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045278">
        <property type="term" value="C:plasma membrane respiratory chain complex IV"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004129">
        <property type="term" value="F:cytochrome-c oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006119">
        <property type="term" value="P:oxidative phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01661">
        <property type="entry name" value="cbb3_Oxidase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.210.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023616">
        <property type="entry name" value="Cyt_c_oxase-like_su1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036927">
        <property type="entry name" value="Cyt_c_oxase-like_su1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000883">
        <property type="entry name" value="Cyt_C_Oxase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023615">
        <property type="entry name" value="Cyt_c_Oxase_su1_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004677">
        <property type="entry name" value="Cyt_c_oxidase_cbb3_su1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10422">
        <property type="entry name" value="PTHR10422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10422:SF29">
        <property type="entry name" value="PTHR10422:SF29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00115">
        <property type="entry name" value="COX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81442">
        <property type="entry name" value="SSF81442"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00780">
        <property type="entry name" value="ccoN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50855">
        <property type="entry name" value="COX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00077">
        <property type="entry name" value="COX1_CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0249">Electron transport</keyword>
    <keyword evidence="10 11" id="KW-0349">Heme</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="8 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="6 11 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="134"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="164"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="206"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="239"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="276"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="308"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="348"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="380"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="436"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="domain" description="COX1" evidence="13">
        <location>
            <begin position="19"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
            <label>B</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="259"/>
        </location>
        <ligand>
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
            <label>B</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="260"/>
        </location>
        <ligand>
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
            <label>B</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR604677-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEZ41065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="476" mass="53424" checksum="6F9B7E90F8C13B8A" modified="2010-01-19" version="1">MSQIKQLEQNYNYTVVRQFTIATILWGIVGMGVGVLIAAQLVWPALNFDTPWLTYSRLRPLHTNAVIFAFGTCALFATSYYVVQRTCQTNLFGGKLAAFTFWGWQAIIVAAAISLPMGWTSGKEYAELEWPIDIAIAIVWVTYAVVFFGTIAKRNTTHIYIANWFFGAFILTVAVLHIVNSLAIPVSMTKSYSIYAGAVDAMVQWWYGHNAVGFLLTAGFLGMMYYFVPKQAGRPIYSYRLSIVHFWALISLYIWAGPHHLHYTALPDWTQSLGMVMSLILFAPSWGGMINGIMTLSGAWHKLRTDPILRFLVVSLSFYGMSTFEGPMMSIKTVNALSHYTDWTIGHVHSGALGWVAMISIGAVYHLLPKLFGQERMYSIKLINVHFWLATVGTVLYIVAMWISGVMQGLMWRAVNTDGTLTYSFVESLQASYPFYFIRFVGGAIFLSGMFLMAYNAYKTIYAPKASLKAIEEQPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXT6</accession>
    <name>D0YXT6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Cbb3-type cytochrome c oxidase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">VDA_002099</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15 17">
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
        </cofactor>
        <text evidence="15 17">Binds 2 heme C groups per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 15">Energy metabolism; oxidative phosphorylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Component of the cbb3-type cytochrome c oxidase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="15">Cell inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the CcoP / FixP family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299430.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002099"/>
    <dbReference type="EnsemblBacteria" id="EEZ41067">
        <property type="protein sequence ID" value="EEZ41067"/>
        <property type="gene ID" value="VDA_002099"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2010">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1315115at2"/>
    <dbReference type="UniPathway" id="UPA00705"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070469">
        <property type="term" value="C:respirasome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006119">
        <property type="term" value="P:oxidative phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.280.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032858">
        <property type="entry name" value="CcoP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038414">
        <property type="entry name" value="CcoP_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008168">
        <property type="entry name" value="Cyt_C_IC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004678">
        <property type="entry name" value="Cyt_c_oxidase_cbb3_su3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13442">
        <property type="entry name" value="Cytochrome_CBB3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14715">
        <property type="entry name" value="FixP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000006">
        <property type="entry name" value="Cbb3-Cox_fixP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00605">
        <property type="entry name" value="CYTCHROMECIC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00782">
        <property type="entry name" value="ccoP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 15" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3 15" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="15" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5 15 17" id="KW-0349">Heme</keyword>
    <keyword evidence="9 15" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="13 15" id="KW-0406">Ion transport</keyword>
    <keyword evidence="12 15 16" id="KW-0408">Iron</keyword>
    <keyword evidence="14 15 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 15 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 15 20" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="15" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="6 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 18" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="15" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="19">
        <location>
            <begin position="155"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="19">
        <location>
            <begin position="241"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="binding site" description="covalent" evidence="17">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="17">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="16">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="16">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>2</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="17">
        <location>
            <position position="253"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="17">
        <location>
            <position position="256"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="16">
        <location>
            <position position="257"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>2</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="16">
        <location>
            <position position="298"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRNR" id="PIRNR000006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR000006-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR000006-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="EEZ41067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="330" mass="36112" checksum="4F55A534D2E10EC9" modified="2010-01-19" version="1">MTTFWSLWITIITLGTIAGVAAILYWCAKDKMGVEEGEDMGHEYDGIRELNNPLPKWWLYMFIATILFGLLYLALYPGLGNFKGLLGWQSSDQTVTSVSDSKQSMELAKQNKAINQYVRELTQADSFFGETFKTLAYSPDGQQLLPISQIAQNQDALKVGQRLFLQNCAQCHGSDARGQAGFPNLADHAWLYGGEAQAIKTTIIQGRQGVMPAWSDSLGVEGLQEVTSYVLSLSGRKVNAKEAAAGKQRFVVCAACHGTDGKGNPAFGAPDLTDNIWLYGGSRQAVLDTIAYGRQGVMPAWGDILGEDKVQLISSYVWSLTNNDDDDSNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXV8</accession>
    <name>D0YXV8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Formate dehydrogenase-O gamma subunit</fullName>
            <ecNumber evidence="12">1.2.1.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">VDA_002121</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the formate dehydrogenase gamma subunit family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.2" evidence="12"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299489.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002121"/>
    <dbReference type="EnsemblBacteria" id="EEZ41089">
        <property type="protein sequence ID" value="EEZ41089"/>
        <property type="gene ID" value="VDA_002121"/>
    </dbReference>
    <dbReference type="GeneID" id="57341749"/>
    <dbReference type="eggNOG" id="COG2864">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1612137at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009326">
        <property type="term" value="C:formate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008863">
        <property type="term" value="F:formate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011577">
        <property type="entry name" value="Cyt_b561_bac/Ni-Hgenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016174">
        <property type="entry name" value="Di-haem_cyt_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006471">
        <property type="entry name" value="Formate_DH_gsu"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01292">
        <property type="entry name" value="Ni_hydr_CYTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81342">
        <property type="entry name" value="SSF81342"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01583">
        <property type="entry name" value="formate-DH-gamm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="6 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019220" evidence="10">
        <location>
            <begin position="27"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="95"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="182"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="241"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="277"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="Ni_hydr_CYTB" evidence="11">
        <location>
            <begin position="130"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ41089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="345" mass="39155" checksum="4DAA78DDC72941CD" modified="2010-01-19" version="1">MTKRIQRWLTVVFTALMVAFSASVLAADNSSSNDLTAGESVVKREVIGFAGADYWRAVKDGQKGYTTSGWPEHDVLISVPGQTWYILKEKWMSPLGALAIFGSLAMVTLAYFVVGPLKLSKPKTGRKIQRWSRMDRALHWSMAFTFLTLGFSGLTLVYGKHFLKPILSTDVWGWVIFAAKQYHNYMGPIFAILLFAVLIKWWRKSIFNKVDIQWFMKMGGMVGKHKGSHPSAGFSNGGEKVIFWLLIFFGIFITVSGFVLDFPIFDQTRRHMELSNLIHMFSALILICGFIFHIYIGLFGMEAGLDGMITGEVDETWAREHHNLWFDEVKDLPENQPKENTTKNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXW1</accession>
    <name>D0YXW1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002124</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299495.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002124"/>
    <dbReference type="EnsemblBacteria" id="EEZ41092">
        <property type="protein sequence ID" value="EEZ41092"/>
        <property type="gene ID" value="VDA_002124"/>
    </dbReference>
    <dbReference type="GeneID" id="57341746"/>
    <dbReference type="eggNOG" id="ENOG5033B11">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014177">
        <property type="entry name" value="Formate_DH_TAT-contain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019546">
        <property type="entry name" value="TAT_signal_bac_arc"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036704">
        <property type="entry name" value="UCP036704"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02811">
        <property type="entry name" value="formate_TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01409">
        <property type="entry name" value="TAT_signal_seq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="66" mass="7294" checksum="65E1B516DD2026F9" modified="2010-01-19" version="1">MSEQKKLNESRRQLLKNIGLTAAAGAIAAGTTTAVQAAAKSEEKKEETKTKGYHETQHIRDYYNTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXZ6</accession>
    <name>D0YXZ6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Sigma-54 dependent response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_002159</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299563.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002159"/>
    <dbReference type="EnsemblBacteria" id="EEZ41127">
        <property type="protein sequence ID" value="EEZ41127"/>
        <property type="gene ID" value="VDA_002159"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2204">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="123059at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002197">
        <property type="entry name" value="HTH_Fis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025943">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025944">
        <property type="entry name" value="Sigma_54_int_dom_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02954">
        <property type="entry name" value="HTH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00158">
        <property type="entry name" value="Sigma54_activat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01590">
        <property type="entry name" value="HTHFIS"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00676">
        <property type="entry name" value="SIGMA54_INTERACT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00688">
        <property type="entry name" value="SIGMA54_INTERACT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50045">
        <property type="entry name" value="SIGMA54_INTERACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Response regulatory" evidence="8">
        <location>
            <begin position="12"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="7">
        <location>
            <begin position="150"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="6">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="492" mass="55319" checksum="2C2989402AA72C84" modified="2010-01-19" version="1">MTDFSSSWTAVSVLVVDDEPGMRTILQKALSKKFAQVDVAGSVEEAEEIRKRCHFDLLIVDINLPGRSGIDWHEAFDPTTKRSDVIFMTGYADLEMAIKALRAGASDFILKPFNLEQMMQSVSRCIERRLMERQNFALQRDVERSYPVEIIGDAASTQRMKKMIAQVAPSLAAVLVEGESGTGKELVARALHQLSKRSGPFVPLNCGAIAPDLLESELFGHVSGAFTGAKKAREGLFRVANNGTLFLDEIGEMPLSMQSSLLRALEQKAIRPVGAEREISVDVRIVAATNRNLKEEVEAGRFRRDLFYRLNVLTIELPALRERIEDIPALAHHFTHQLAKDLGMQSISWTHEDIVAMQAYDWPGNIRELRNLMERCILLGKPPADYWRELNDDFPVSHDVDSKLNEEHSITSGDSVTNVGDERPCRCHENGQEQYCYPTDWTLKEVEKAHILQVVDSNDGNKSAAARQLGVARKTLERKFKEWSDEVEELKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY16</accession>
    <name>D0YY16_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Bcr/CflA family efflux transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_002179</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell inner membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Bcr/CmlA family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299598.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002179"/>
    <dbReference type="EnsemblBacteria" id="EEZ41147">
        <property type="protein sequence ID" value="EEZ41147"/>
        <property type="gene ID" value="VDA_002179"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1452500at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990961">
        <property type="term" value="P:xenobiotic detoxification by transmembrane export across the plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004812">
        <property type="entry name" value="Efflux_drug-R_Bcr/CmlA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00710">
        <property type="entry name" value="efflux_Bcr_CflA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="9"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="104"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="137"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="167"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="216"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="253"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="282"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="306"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="347"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="372"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="8">
        <location>
            <begin position="10"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="396" mass="42704" checksum="2D1FF6FD0DE6129A" modified="2010-01-19" version="1">MTSNQPQKLTFQFILLLGAISALTPLAIDMYLPAMPSIAKDFAVSPSFVQTTLTAYTAGFAVGQLLHGPLADSFGRKPILIIGTICFLIATVLGATSSNITELTWIRVAQGFAGAAAAVIIQALVRDMFEREEFARTMSFITLVMTVAPLAAPMIGGYFSVWFGWRSVFWFLAIFATLVIIAISFKIKETLPEEKRLPFNLAGTLRNYIKLMTNPIAVGLVLTSGFSFAGMFTFLTVGSFVYIDLYGISPEAFGYYFGLNIICLIVMTSINGRMVKKKGSHWMLRFGLIVQLLAGIGLIVGQLLNLGLWGTVIPVMIFVGTISIIGSNTMACLLGRYPHMAGTASSLAGTLRFGTGSLVGGIVAMMPDATAWPMAMTMASCAFLSAGFYWLLSRDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY59</accession>
    <name>D0YY59_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Ferric siderophore transport system biopolymer transport protein ExbB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_002222</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the exbB/tolQ family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299679.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002222"/>
    <dbReference type="EnsemblBacteria" id="EEZ41190">
        <property type="protein sequence ID" value="EEZ41190"/>
        <property type="gene ID" value="VDA_002222"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0811">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1796180at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002898">
        <property type="entry name" value="MotA_ExbB_proton_chnl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01618">
        <property type="entry name" value="MotA_ExbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="115"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="166"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="MotA_ExbB" evidence="8">
        <location>
            <begin position="72"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="223" mass="24472" checksum="C197479F73CA51D0" modified="2010-01-19" version="1">MEFINQYQEQFGLMAWPLFICSLLTVMILLERFIQVLLCTGVGKTKINQILNNQNRHDEQALDHLAQQLQNQRPLLYKGIAMLISHRHFAKALREDAAGMWLQQKRTQLRSGLKLLSLIGVISPLLGLLGTVLGLIDMFKGIAMTTGSVTPNDLADGLGLAMRTTAAGLIIALPAITGAQLLGLWADSITSKLEHSLNRCNLWLEGISVTTNCDKPAQGEALS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY62</accession>
    <name>D0YY62_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC-type hemin transport system ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_002225</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299687.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002225"/>
    <dbReference type="EnsemblBacteria" id="EEZ41193">
        <property type="protein sequence ID" value="EEZ41193"/>
        <property type="gene ID" value="VDA_002225"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4559">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1752365at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="13"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="45"/>
            <end position="52"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="265" mass="28622" checksum="4C9E953DACC6E720" modified="2010-01-19" version="1">MSSTLSSHHAIALKASNLHLQLGGKTLLDDIDLEIMSGQITALLGPNGAGKSSLLKVLNGEITPNSGSIEIFSRPKDHWPSELLAKHMGILPQHSTLSFSFLAHEVAELGAMPLAISNHQAQQLAAKNMVKVGVDHLANRLYPTLSGGEKQRVHFARVLTQLSHSGKQCILMLDEPTSALDLAHQHHTLEIAQALSQQGAAVIIVIHDLNLAAQYADRLIILNQGKIQADGTPWQVLTPTAVENVYGWPVQVIAHPEHNYPVILA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY95</accession>
    <name>D0YY95_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002258</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299743.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002258"/>
    <dbReference type="EnsemblBacteria" id="EEZ41226">
        <property type="protein sequence ID" value="EEZ41226"/>
        <property type="gene ID" value="VDA_002258"/>
    </dbReference>
    <dbReference type="GeneID" id="57341585"/>
    <dbReference type="eggNOG" id="ENOG5033KTS">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1950609at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="89" mass="10154" checksum="79093A438C250B27" modified="2010-01-19" version="1">MENQDEIMTGDMLVETVENQLADSNPIVVKETLMRLMMTGTSREDAIEMMACALSIEVFDVMKNEGKFDLKRYSENLSALPDMPWTDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYB2</accession>
    <name>D0YYB2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Substrate-specific component MtsA of methionine-regulated ECF transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002275</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299771.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002275"/>
    <dbReference type="EnsemblBacteria" id="EEZ41243">
        <property type="protein sequence ID" value="EEZ41243"/>
        <property type="gene ID" value="VDA_002275"/>
    </dbReference>
    <dbReference type="GeneID" id="57341548"/>
    <dbReference type="eggNOG" id="COG4720">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1637464at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009825">
        <property type="entry name" value="ECF_substrate-spec-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07155">
        <property type="entry name" value="ECF-ribofla_trS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="143"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="183" mass="19693" checksum="F876E329602799A6" modified="2010-01-19" version="1">MSLSAKTVVLIAIGAALYGIGGLPMFGIPVFANTTLKPAMAVLALFGVLFGPLVGFLVGFIGHWVTDLFAGWGVWFTWVLGSGIVGLIIGLYPKITRGRLEMGKFTKWDFALFVLLAFLGNTIGYGTSAFLDYLLYAEPLTKVLAQVTIIAAGNTILIAIVGHFILTSVAKRKQRSFNLKEAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYE5</accession>
    <name>D0YYE5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Asparagine--tRNA ligase</fullName>
            <ecNumber evidence="5">6.1.1.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Asparaginyl-tRNA synthetase</fullName>
            <shortName evidence="5">AsnRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">asnS</name>
        <name evidence="7" type="ORF">VDA_002308</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + L-asparagine + tRNA(Asn) = AMP + diphosphate + H(+) + L-asparaginyl-tRNA(Asn)</text>
            <dbReference type="Rhea" id="RHEA:11180"/>
            <dbReference type="Rhea" id="RHEA-COMP:9659"/>
            <dbReference type="Rhea" id="RHEA-COMP:9674"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58048"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78515"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.22"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.22" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299833.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002308"/>
    <dbReference type="EnsemblBacteria" id="EEZ41276">
        <property type="protein sequence ID" value="EEZ41276"/>
        <property type="gene ID" value="VDA_002308"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0017">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1138123at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004816">
        <property type="term" value="F:asparagine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006421">
        <property type="term" value="P:asparaginyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00534">
        <property type="entry name" value="Asn_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004522">
        <property type="entry name" value="Asn-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00457">
        <property type="entry name" value="asnS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 7" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 5 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="6">
        <location>
            <begin position="139"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="466" mass="52638" checksum="8D58EEEFCD569428" modified="2010-01-19" version="1">MTYAPVTDVLSGKLAVDSEVTVRGWIRSRRDSKAGISFLAIYDGSCFNPIQAVVPNELNNYQSEVLKLTTGCSVEVTGKIVESPAQGQDFELAATDVKVVGWVEDADTYPMAKTRHSIEYLREVAHLRPRTNVIGAVARVRNCLAQAIHRFYHEQGFFWMSAPLITASDCEGAGEMFRVSTLDLANLPMTDKGDVDFDKDFFGKETFLTVSGQLNAEAYACALSKVYTFGPTFRAENSNTSRHLAEFWMVEPEVAFAELDDVAKLAEDMLKFVFKAVLEERRDDLEFFAQRIDKDAITRLEQFVSSDFAQVDYTDAIKILQDSGRKFEFDVEWGIDMSSEHERFLAEEHFKAPVIVKNYPKDIKAFYMRMNEDGKTVAAMDVLAPGIGEIIGGSQREERLDILDARMREMNIDPEHMNWYRDLRRYGTVPHAGFGLGFERLVSYVTGMGNVRDVIPFPRTPRSASF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYG7</accession>
    <name>D0YYG7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L35</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpmI</name>
        <name evidence="7" type="ORF">VDA_002330</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the bacterial ribosomal protein bL35 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299888.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002330"/>
    <dbReference type="EnsemblBacteria" id="EEZ41298">
        <property type="protein sequence ID" value="EEZ41298"/>
        <property type="gene ID" value="VDA_002330"/>
    </dbReference>
    <dbReference type="GeneID" id="57341482"/>
    <dbReference type="eggNOG" id="COG0291">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2046660at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.410.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00514">
        <property type="entry name" value="Ribosomal_L35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021137">
        <property type="entry name" value="Ribosomal_L35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018265">
        <property type="entry name" value="Ribosomal_L35_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001706">
        <property type="entry name" value="Ribosomal_L35_non-mt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037229">
        <property type="entry name" value="Ribosomal_L35_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33343">
        <property type="entry name" value="PTHR33343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01632">
        <property type="entry name" value="Ribosomal_L35p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00064">
        <property type="entry name" value="RIBOSOMALL35"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143034">
        <property type="entry name" value="SSF143034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00001">
        <property type="entry name" value="rpmI_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00936">
        <property type="entry name" value="RIBOSOMAL_L35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="64" mass="7296" checksum="7F746081CCF7B086" modified="2010-01-19" version="1">MPKMKSNKGAAKRFKKTGGGFKYKHATKRHILTKRTTKNKRQLRPNAILPKCEVAAVVRMLPYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYP4</accession>
    <name>D0YYP4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">tRNA-binding protein YgjH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_002407</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300034.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002407"/>
    <dbReference type="EnsemblBacteria" id="EEZ41375">
        <property type="protein sequence ID" value="EEZ41375"/>
        <property type="gene ID" value="VDA_002407"/>
    </dbReference>
    <dbReference type="GeneID" id="57341387"/>
    <dbReference type="eggNOG" id="COG0073">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2038415at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002547">
        <property type="entry name" value="tRNA-bd_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01588">
        <property type="entry name" value="tRNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50886">
        <property type="entry name" value="TRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 3" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="TRNA-binding" evidence="4">
        <location>
            <begin position="8"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="110" mass="12338" checksum="BA7094DFD6E35264" modified="2010-01-19" version="1">METIAYSDFAKLDIRVGKIIEVKRHDNADKLYIVQIDVGEKTLQTVTSLVPYYTEEELMGKQVVVLCNLAKAKMRGETSECMLLCAETEDESESVLLTPERLMPAGVKIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYR3</accession>
    <name>D0YYR3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative resistance protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_002426</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300070.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002426"/>
    <dbReference type="EnsemblBacteria" id="EEZ41394">
        <property type="protein sequence ID" value="EEZ41394"/>
        <property type="gene ID" value="VDA_002426"/>
    </dbReference>
    <dbReference type="GeneID" id="57341363"/>
    <dbReference type="eggNOG" id="COG2223">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1594866at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="78"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="100"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="134"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="166"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="216"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="247"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="282"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="307"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="341"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="366"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="9"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="403" mass="42625" checksum="96C8CEFC5B925BE3" modified="2010-01-19" version="1">MASAITKQSRIFTLIGTIITQFALGSVYTWSLFNSPLADKLSEPVNRVAFSFGILSLALAVASSLSGKLQERFGVRKVTIGAGLLLGASLLLTAHASNLILLYVFAGLLVGFADGTGYLLTLSNCVKFFPERKGLASACAIGAYGLGSLGFKYINMYLLTHMGLDMTFDVWGAIAMVMVIIGGLMMTDAPKQQVSANNSAEQRDYTLAEAMKCSQFWLLALVFLTVCMSGLYVIGVAKDIGQDYVHLSVTTAASAVAIIAVANLSGRLVLGILSDRIARTKVIAIALAVCLVGVCSLLFAHQSMLSFYVAVACIAFSFGGTITVFPSLVSDFFGLNNLAKNYGLIYLGFGIGSFVGSIVASVFGGFIATFYLMFALLVVSLIIALTIKIPGQTGIKQQIIMAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYW5</accession>
    <name>D0YYW5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Probable septum site-determining protein MinC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">minC</name>
        <name evidence="9" type="ORF">VDA_002478</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Interacts with MinD and FtsZ.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the MinC family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300169.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002478"/>
    <dbReference type="EnsemblBacteria" id="EEZ41446">
        <property type="protein sequence ID" value="EEZ41446"/>
        <property type="gene ID" value="VDA_002478"/>
    </dbReference>
    <dbReference type="GeneID" id="57341300"/>
    <dbReference type="eggNOG" id="COG0850">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1665744at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000902">
        <property type="term" value="P:cell morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000917">
        <property type="term" value="P:division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051302">
        <property type="term" value="P:regulation of cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901891">
        <property type="term" value="P:regulation of cell septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00267">
        <property type="entry name" value="MinC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016098">
        <property type="entry name" value="CAP/MinC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013033">
        <property type="entry name" value="MinC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036145">
        <property type="entry name" value="MinC_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007874">
        <property type="entry name" value="MinC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005526">
        <property type="entry name" value="Septum_form_inhib_MinC_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34108">
        <property type="entry name" value="PTHR34108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03775">
        <property type="entry name" value="MinC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05209">
        <property type="entry name" value="MinC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63848">
        <property type="entry name" value="SSF63848"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01222">
        <property type="entry name" value="minC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 6" id="KW-0132">Cell division</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0717">Septation</keyword>
    <feature type="domain" description="MinC_N" evidence="8">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="MinC_C" evidence="7">
        <location>
            <begin position="115"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF05209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="220" mass="23624" checksum="1F57CEA4214E985B" modified="2010-01-19" version="1">MTKSAELKGSSFTLSALHLNDGDITTALTQLKEKVDRAPNFFASAPLVIDISQAGSKIDFAQLKSGITKAGMIPVGISGCKNPQMQDKAKQNGFAIMNAARQLQASEPEMVPTKIIRTPVRSGQQIYAKNSDLIIMNHVSAGAEIIADGCIHVYGTLRGRAIAGANGQHQAQIFCQNLQSELVSIAGCYWLSDKIPEEFWGKGVVISLTENNLNIEPLAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYW8</accession>
    <name>D0YYW8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribonuclease D</fullName>
            <shortName evidence="4">RNase D</shortName>
            <ecNumber evidence="4">3.1.13.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rnd</name>
        <name evidence="6" type="ORF">VDA_002481</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>Exonucleolytic cleavage that removes extra residues from the 3'-terminus of tRNA to produce 5'-mononucleotides.</text>
            <dbReference type="EC" id="3.1.13.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RNase D family.</text>
    </comment>
    <dbReference type="EC" id="3.1.13.5" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300173.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002481"/>
    <dbReference type="EnsemblBacteria" id="EEZ41449">
        <property type="protein sequence ID" value="EEZ41449"/>
        <property type="gene ID" value="VDA_002481"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0349">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1462689at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033890">
        <property type="term" value="F:ribonuclease D activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042780">
        <property type="term" value="P:tRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.80">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01899">
        <property type="entry name" value="RNase_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002562">
        <property type="entry name" value="3'-5'_exonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010997">
        <property type="entry name" value="HRDC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002121">
        <property type="entry name" value="HRDC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044876">
        <property type="entry name" value="HRDC_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006292">
        <property type="entry name" value="RNase_D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01612">
        <property type="entry name" value="DNA_pol_A_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00570">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00474">
        <property type="entry name" value="35EXOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47819">
        <property type="entry name" value="SSF47819"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01388">
        <property type="entry name" value="rnd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50967">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="HRDC" evidence="5">
        <location>
            <begin position="210"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="382" mass="43565" checksum="0B4D441F84D974C3" modified="2010-01-19" version="1">MEFTIITTTADLKMVCQAASSAPAIMLDTEFVRTRTLYPKLGLIQLFDGKQLSLIDPLAIEDMEPLWDLLRDQSVMKVLHACGEDLEVFQHHAGCLPVPMLDTQLMAAFLGHGVSTGFGALVKEYVGVELDKGEARTNWLARPLTDRQLNYAAADVFYLLPLYETLLEKVGAAGYCKALEQECNATMLKRVKQADPSKAYLNIKNAWQLNPKQLAILQKLAAWRVLESQKRDIAVNFIVKELNLWKIARYNIKSKAVMEKEGFEPMEIQRHANRLLKMVYDVDSMSAFDYPDKIQRLVDFAGYKQAVKRLKDVVVDVEKKTGLAPEFLASKKQIHQVLSWAWKHQYAEDKRPEMLKTWRKPLFEERVMGLLEKMSPNSASLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ96</accession>
    <name>D0YZ96_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Flagellar hook-associated protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_002609</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Bacterial flagellum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the flagella basal body rod proteins family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300477.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002609"/>
    <dbReference type="EnsemblBacteria" id="EEZ41577">
        <property type="protein sequence ID" value="EEZ41577"/>
        <property type="gene ID" value="VDA_002609"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1256">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1815809at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009424">
        <property type="term" value="C:bacterial-type flagellum hook"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044780">
        <property type="term" value="P:bacterial-type flagellum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001444">
        <property type="entry name" value="Flag_bb_rod_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010930">
        <property type="entry name" value="Flg_bb/hook_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002371">
        <property type="entry name" value="FlgK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30033">
        <property type="entry name" value="PTHR30033"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00460">
        <property type="entry name" value="Flg_bb_rod"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06429">
        <property type="entry name" value="Flg_bbr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01005">
        <property type="entry name" value="FLGHOOKAP1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02492">
        <property type="entry name" value="flgK_ends"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="9" id="KW-0966">Cell projection</keyword>
    <keyword evidence="9" id="KW-0969">Cilium</keyword>
    <keyword evidence="9" id="KW-0282">Flagellum</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Flg_bb_rod" evidence="7">
        <location>
            <begin position="6"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="Flg_bbr_C" evidence="8">
        <location>
            <begin position="615"/>
            <end position="658"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF06429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="661" mass="70984" checksum="6FFBA8F64B0D5DA2" modified="2010-01-19" version="1">MALDLMQIGMSGLRTSQKQLDVASHNISNVNTPGYSRQVVEQKADDAFYNGSNYYGTGAYIDNVSRAYDQFAARELTLSTTHLEEANVRQQNMMMLDDFTSKSAVNTVNSMNDFYNSVRSLSDHPNDLGARQTVLEQAKQTAQSFQTSHQTLTNMHQDVTDQIGVSLERINTLGQELAAVNTSLQEQAASGKSNDLFDKQRSLINELAKYTKVTVLADKGSLANTVIIGSGDTLVSGVTSAKLKLVNGKPDTQTQQIALVTGNSAKEIKSDGIGGSLGSLLDIRDNVIDKSLDEMGRMAIGFSKQINDLQQQGVDLNGEQGALLFSDVNSVSAMQQRAIKPLGSNAEIQVSIDDVNQLKTGDYQLDMNFDGTNYNYTVTDQDGKQTTISDTSQKQSLSVDGFSINIEKAFSTPTAGQSESILIRPVRDGAANMAVEMSDPKKLAGHSQLAVMPHQANQGSASVIKTVPQLSDALAGVYELKVNNSGNKISLINQATGQPMTLIDDKGSEVTELGYDSAKPQNLTVKTDAGDLSGLALQAGALAGDSFQLNLGRAQATGGNGNFLAMQQVQAQKSMNNGKSSVIDLFQKLSTDIGMAKKNADQTAEVTQLDFDAASERVSNLSGVNLDEEAANLMKFQQSYMASSRIMSVAKETFDTLMRAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZB0</accession>
    <name>D0YZB0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FlgO domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002623</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002623"/>
    <dbReference type="EnsemblBacteria" id="EEZ41591">
        <property type="protein sequence ID" value="EEZ41591"/>
        <property type="gene ID" value="VDA_002623"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5616">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014549">
        <property type="entry name" value="FlgO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041215">
        <property type="entry name" value="FlgO_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17680">
        <property type="entry name" value="FlgO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028688">
        <property type="entry name" value="UCP_imp_028688"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FlgO" evidence="1">
        <location>
            <begin position="75"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF17680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="237" mass="26764" checksum="D2655E1E5ECA948B" modified="2010-01-19" version="1">MILNIFKVFMNFDDKQSDGRSNWSKRMKIWWAVALTLLVTSCSSPAVYNGREPYPGASFSLTETPRHTLDYFIQGMADQLVQSNQYLTAQTPVAVTSFVDLQSMSETNWLGNAVTESFMYQLQHRGFTVVDYKITGSIKVTQAGDFTISRDWRELAPQQSVDYVLTGTMLRQSGGVMINARIVGMRSRVVIASAQGFLPADRIGRDLDFMNKIQMRNGVLIRNDINKLSDNNVILRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZG0</accession>
    <name>D0YZG0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Octaprenyl-diphosphate synthase/dimethylallyltransferase/geranyltranstransferase/ geranylgeranyl pyrophosphate synthetase</fullName>
            <ecNumber evidence="3">2.5.1.1</ecNumber>
            <ecNumber evidence="3">2.5.1.10</ecNumber>
            <ecNumber evidence="3">2.5.1.29</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002673</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the FPP/GGPP synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.1" evidence="3"/>
    <dbReference type="EC" id="2.5.1.10" evidence="3"/>
    <dbReference type="EC" id="2.5.1.29" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300670.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002673"/>
    <dbReference type="EnsemblBacteria" id="EEZ41641">
        <property type="protein sequence ID" value="EEZ41641"/>
        <property type="gene ID" value="VDA_002673"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0142">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1861068at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004161">
        <property type="term" value="F:dimethylallyltranstransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004311">
        <property type="term" value="F:farnesyltranstransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004337">
        <property type="term" value="F:geranyltranstransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00685">
        <property type="entry name" value="Trans_IPPS_HT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033749">
        <property type="entry name" value="Polyprenyl_synt_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00723">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00444">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="299" mass="32613" checksum="0D4277819D9ADF11" modified="2010-01-19" version="1">MTNSSLLQLLQHYQERNNQQLTHWLDAQPFADQTLLKAMKYGALLGGKRVRPFLTYVTGNMLGVNEENLDTPAAAIECIHAYSLIHDDLPAMDDDELRRGQPTCHIAFDEATAVLAGDALQTLAFEILAEGTLSIDGESQRIKMIKELAQASGAAGMCMGQALDLDGEGKHLGLTQLEQIHKHKTGALIRCAVRLGALAAGEKGLEILPQLNTYAEAIGLAFQVQDDILDVISDTETLGKPQGSDIALDKSTYPALLGLEGAQQKAQQLYQEAVQALEAIPYDTTQLEVFARYLIERKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZJ4</accession>
    <name>D0YZJ4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Peptidase B</fullName>
            <ecNumber evidence="8">3.4.11.23</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_002707</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M17 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.23" evidence="8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300759.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002707"/>
    <dbReference type="MEROPS" id="M17.004"/>
    <dbReference type="EnsemblBacteria" id="EEZ41675">
        <property type="protein sequence ID" value="EEZ41675"/>
        <property type="gene ID" value="VDA_002707"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0260">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="356206at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00433">
        <property type="entry name" value="Peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011356">
        <property type="entry name" value="Leucine_aapep/pepB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008330">
        <property type="entry name" value="Pept_M17_PepB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000819">
        <property type="entry name" value="Peptidase_M17_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11963">
        <property type="entry name" value="PTHR11963"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12404">
        <property type="entry name" value="DUF3663"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00883">
        <property type="entry name" value="Peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036388">
        <property type="entry name" value="Ctsl_amnpptdse_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00481">
        <property type="entry name" value="LAMNOPPTDASE"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00631">
        <property type="entry name" value="CYTOSOL_AP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0464">Manganese</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CYTOSOL_AP" evidence="7">
        <location>
            <begin position="275"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ41675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="428" mass="45786" checksum="1D7ABE2C54E8DDD7" modified="2010-01-19" version="1">MSTNMLVFLSQQPADDKWGNNALVSFDANGAVIHLTGSDPLLTIQRAARKLDSQGMKQLELAGDGWELERIWAFLLGQRSSKTVKTATWPTLSEAEETELAARLQTTNWVRGIINQPADEVRPSQLTARAAEFIKSLAPEHVTYKIIKGNDLRDEGWNGTYTVGRGSDHRPAMLRLDYNPTGNPDAPVFACLVGKGITFDSGGYSIKPSAGMAAMKADMGGAALVTGGLAMAIARGLNKRIKLVLCCAENMISGRAAKLGDVITYKNGKTVEILNTDAEGRLVLADGLIYASSQNPELIIDCATLTGAAKMAVGNDYHSLLTFDNSLAQKALSAAQAEGEGMWPLPLAEIHRGMLPSNFADLANISSGDFMPGASTAAAFLSYFVEDYHQGWMHIDASATYRKGANDMWGAGATGVGVRTLANILTQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZJ5</accession>
    <name>D0YZJ5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">2Fe-2S ferredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_002708</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the adrenodoxin/putidaredoxin family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300762.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002708"/>
    <dbReference type="EnsemblBacteria" id="EEZ41676">
        <property type="protein sequence ID" value="EEZ41676"/>
        <property type="gene ID" value="VDA_002708"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0633">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1837979at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140647">
        <property type="term" value="P:P450-containing electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001055">
        <property type="entry name" value="Adrenodoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018298">
        <property type="entry name" value="Adrenodoxin_Fe-S_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011536">
        <property type="entry name" value="Fdx_isc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23426">
        <property type="entry name" value="PTHR23426"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00355">
        <property type="entry name" value="ADRENODOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02007">
        <property type="entry name" value="fdx_isc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00814">
        <property type="entry name" value="ADX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="4">
        <location>
            <begin position="2"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="112" mass="12307" checksum="34117E6CD65DA326" modified="2010-01-19" version="1">MPKIVVLPNEDLCPEGAVLEAKAGESVLDVALRNGIEIEHACEKSCACTTCHVIIREGFDSLEESDELEDDMLDKAWGLEPESRLGCQALVADEDLVVEIPRYTVNLAKENH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZM5</accession>
    <name>D0YZM5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Exonuclease SbcC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002738</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300867.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002738"/>
    <dbReference type="EnsemblBacteria" id="EEZ41706">
        <property type="protein sequence ID" value="EEZ41706"/>
        <property type="gene ID" value="VDA_002738"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0419">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1143316at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="229"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="376"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="635"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="726"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="835"/>
            <end position="886"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="1265" mass="142548" checksum="CE7D05A07AB316A1" modified="2010-01-19" version="1">MKILALRGENLASLQSQFEIDFAGGRLGDAGLFAITGKTGAGKSTLLDAICLALFDRIPRLQSNKKNDAEIGRDDDDNRIKANDVRSILSRGKGEGFAEVDFVANDGSYWRAHWHVRRARGRAEGKIQAAEQWLENIETGQRFAGKKQELQAEIENLIGLSFDQFRRAVMLPQGEFAAFLKAGADERAALLERMTGGEIYGRLSIAAHERAKDEKLKLTQLQGKLGDIALLTDEEREALNAQLATAREQVSHQQQKLELLKQHQDVLVNAEKLTHRVGESEQQLEQAKQAQQLAEPRYRQLNQYEQALPARGDFTLLSQAQQQVIKWQQILQSTTAELTAKQQQQGQWQIQVEQSQQQLTQKQQAFRELEPKLKQAASIEQKRDGLQQQSLELQQQLASLNKELTAQRDQLVNHQQQQQTAQSQLQQVTTALMQAQGVKALAEQQNAIKDNISQYQQAQNQINQLQADIKQRETTLATVTEQLSQLDKQLAVLAQKKQQLTEQITKHDLTALEQLQDQERQHYAAYQQLSSKLKESLFGLDKWHGLLQQRDKFQLQQQGLVNSIASSEQRLAILAPELLKLDVQLKEVEFQLNQSRAVMSLTDYREQLVEGEPCPLCGAAEHPYQQHNPQVDSIINQQQLRLQQLAQQRQEAHTEQHQLTQSIAQDKQRQIELEQEILGLNNTIQGLVDQQQSHWTDLMAVDLDAITLAEIALATDSDLAQLSHYQANWSQALDGAQAQMQQIKAQGEQRKVLIEEVKKQQHHLQQLTEQEAEQKEHGYLLTQQQTQAQEQLNAFTTQVNNLQNVVAERQQALMAIYGNDIWLNALAQQGTAGFIADLELQIQQYQANVEQQLRLEKQLTELAPVLATLTNSVQNGEQQINEITAKVTRLVKDRQACWQQRIELIGEQPLDTIERSAKADIDTQLQQCQQRQTQLNQLAEVIAAELTKQQNATQQLAESELTQQKLSQVWQTWLEKLALTEAELTELLSKDDAWLQQERSELKQLEQAVSQGETIVKERQQAQLDYQPTIDLATQWFNEHNIGDDTSAQQQLFTQWQTEKAQLDDQVFQLRQRLEQGVQAEKQAGDLRTALATQQTQTELWMEMSDLIGSATGNKFRTLAQGLTLQQLVINANEHLYELAPRYALQPVPGSPLALQVIDHDMGDEVRSVESLSGGESFLVSLSLALALASLAADTRQLGSLFIDEGFGTLDPDSLEMALACLDALQADGRQIGVISHVGTLVERIGVQVAVEAQGGGRSRIEIKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZS5</accession>
    <name>D0YZS5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002788</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301008.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41756">
        <property type="protein sequence ID" value="EEZ41756"/>
        <property type="gene ID" value="VDA_002788"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5032T6W">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1116885at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="216" mass="26068" checksum="E6C91C9FDA3ADE8C" modified="2010-01-19" version="1">MSYLIKKQWNKRSVVNEDFNNSYLNSIEKVIDKSIDQYPRILAIRFDLRLPKVNYVDFLDRDLHDGFNRDRLIPRFIDSLKSKIKYDVRRKNKRWKGNYKCDLHYVWCREQDKSDNEHYHVMIIVNKDVYRSIGEYHHDGSLASMIVSAWGSSLSLDYNQGKSLVYFPNNCAYVVNYHDSKYEEQYDDLFRRVSYLAKTRTKNINRYYRSFGCSCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZW5</accession>
    <name>D0YZW5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Lipoprotein NlpI</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_002828</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">May be involved in cell division.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301127.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002828"/>
    <dbReference type="EnsemblBacteria" id="EEZ41796">
        <property type="protein sequence ID" value="EEZ41796"/>
        <property type="gene ID" value="VDA_002828"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4785">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1382732at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023605">
        <property type="entry name" value="Lipoprotein_NlpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004654">
        <property type="entry name" value="NlpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="74"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="108"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR004654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="317" mass="35904" checksum="880540FDD7986A76" modified="2010-01-19" version="1">MPIVERGSGTLLKKMKFAVVSVVLALSGCAGTSQVHWNIPPMAVPFQATMQQQIQLARIEQLLGQKELTDKQVAQLYLQRGLVYDSLGIKDLARMDFAQSLSINPKQADLYNILGVYLTQVGLFDAAYEAFDSTLDLEPSHPYAQRNLGIALYYGERLELAHQELYQHYLQDKNDPYRAIWLYLVDVKTQPQQAARQLQYQYNVSNKKDWGWNIAQLLIGKISEGQFIADIAEQSQDNQQLAEHLTEGYFYLAKQYQLQGDEDAAANLFKLALAGNVYEYVEHRYALLELALMADEEQQQAQALQTTNGNGIESNNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZW7</accession>
    <name>D0YZW7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">30S ribosomal protein S15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rpsO</name>
        <name evidence="7" type="ORF">VDA_002830</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.</text>
    </comment>
    <comment type="function">
        <text evidence="3 6">One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the universal ribosomal protein uS15 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301136.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002830"/>
    <dbReference type="EnsemblBacteria" id="EEZ41798">
        <property type="protein sequence ID" value="EEZ41798"/>
        <property type="gene ID" value="VDA_002830"/>
    </dbReference>
    <dbReference type="GeneID" id="57340888"/>
    <dbReference type="eggNOG" id="COG0184">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1990141at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00353">
        <property type="entry name" value="Ribosomal_S15p_S13e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01343_B">
        <property type="entry name" value="Ribosomal_S15_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000589">
        <property type="entry name" value="Ribosomal_S15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005290">
        <property type="entry name" value="Ribosomal_S15_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009068">
        <property type="entry name" value="S15_NS1_RNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23321">
        <property type="entry name" value="PTHR23321"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00312">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01387">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47060">
        <property type="entry name" value="SSF47060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00952">
        <property type="entry name" value="S15_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00362">
        <property type="entry name" value="RIBOSOMAL_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 6" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="89" mass="10240" checksum="602051FC640B05D5" modified="2010-01-19" version="1">MSLNAETKAAIVAEYAQGQNDTGSPEVQVALLTAQINHLQGHFANHKHDHHSRRGLLRMVSRRRKLLDYLKGKNLDRYQDLIKRLGLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZY6</accession>
    <name>D0YZY6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Isoleucine--tRNA ligase</fullName>
            <ecNumber evidence="10">6.1.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Isoleucyl-tRNA synthetase</fullName>
            <shortName evidence="10">IleRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ileS</name>
        <name evidence="16" type="ORF">VDA_002849</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>ATP + L-isoleucine + tRNA(Ile) = AMP + diphosphate + L-isoleucyl-tRNA(Ile)</text>
            <dbReference type="Rhea" id="RHEA:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:9666"/>
            <dbReference type="Rhea" id="RHEA-COMP:9695"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58045"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78528"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="10">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="10">IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.5" evidence="10"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002849"/>
    <dbReference type="EnsemblBacteria" id="EEZ41817">
        <property type="protein sequence ID" value="EEZ41817"/>
        <property type="gene ID" value="VDA_002849"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0060">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004822">
        <property type="term" value="F:isoleucine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006428">
        <property type="term" value="P:isoleucyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07960">
        <property type="entry name" value="Anticodon_Ia_Ile_BEm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.740.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02002">
        <property type="entry name" value="Ile_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033708">
        <property type="entry name" value="Anticodon_Ile_BEm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002301">
        <property type="entry name" value="Ile-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023585">
        <property type="entry name" value="Ile-tRNA-ligase_type1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010663">
        <property type="entry name" value="Znf_FPG/IleRS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06827">
        <property type="entry name" value="zf-FPG_IleRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00984">
        <property type="entry name" value="TRNASYNTHILE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="SSF50677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00392">
        <property type="entry name" value="ileS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10 11" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 10 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 10 11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="tRNA-synt_1" evidence="13">
        <location>
            <begin position="12"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="domain" description="Anticodon_1" evidence="15">
        <location>
            <begin position="678"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="domain" description="zf-FPG_IleRS" evidence="14">
        <location>
            <begin position="891"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="831"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="10">
        <location>
            <begin position="42"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="10">
        <location>
            <begin position="595"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="554"/>
        </location>
        <ligand>
            <name>L-isoleucyl-5'-AMP</name>
            <dbReference type="ChEBI" id="CHEBI:178002"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="598"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="893"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="896"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="913"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="916"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF06827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EEZ41817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="930" mass="104000" checksum="59D892F23DD923FA" modified="2010-01-19" version="1">MRGNLAQREPAMLKRWYDEDLYGEIRKAKKGKKSFVLHDGPPYANGDIHIGHALNKILKDIIIKSKTLSGFDAPYVPGWDCHGLPIELMVEKKVGKPGQKVTAAEFREKCREYAAGQVEGQKESFIRLGVLGEWDKPYRTMDFNTEANIIRALGKIADNDHLLKGFKPVHWCTDCGSALAEAEVEYQDKVSLSIDVKFKAVDEAAVLAKFGCDADKGQGDVSIVIWTTTPWTMPANRAVAISADLEYALVQTPATEAHPAPQRLIMAAELVKEVMARVGFEESEILGFCKGEELELLRFNHPFYSFDVPVILGEHVTTESGTGCVHTAPGHGQEDFVVGQKYNLEIANPVGSNGVYLPDTEIFAGQHVLKANEAVVEVLREHGSLLNFSKITHSYPHCWRHKTPIIFRATPQWFISMDKAGLRAKALEEIKGVQWMPEWGQSRIEGMVEGRPEWCISRQRTWGVPIALFIHKETQELHPQTSELIEKVAQLVEQKGIQAWWDLELTDVMSAEDAANYEKVLDTLDVWFDSGVTHFAVVDNRPEFNGHSPDLYLEGSDQHRGWFQSSLISSVAMKDKAPYKQVLTHGFVVDGQGRKMSKSIGNVVAPKDVTNKLGADILRLWVASTDYTGEVAVSDEILKRSADAYRRIRNTARFFLANLHGFNPETDCVAPEDMVALDRWAVGRAMAAQEEIVKAYEEYNLHAVTQRLMQFCSVEMGSFYLDVIKDRQYTAKQGGHAQRSCQTALYYILEALVRWMAPIMSFTADEIWNEMPGQRDKFVFTGEWFEGLFGLAEGEELNNEFWAEIQKVRGSVNKLLEAARNEKVIGGSLQAEVTLAANADLAAKLNKLEDELRFVLLTSKAQVVVADSKPADAQETDIDGLYVSVKASEAEKCERCWHHVADVGTIAGHEEVCGRCVSNIDGEGEERKFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0C1</accession>
    <name>D0Z0C1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rplU</name>
        <name evidence="6" type="ORF">VDA_002984</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5">This protein binds to 23S rRNA in the presence of protein L20.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 50S ribosomal subunit. Contacts protein L20.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the bacterial ribosomal protein bL21 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301462.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002984"/>
    <dbReference type="EnsemblBacteria" id="EEZ41952">
        <property type="protein sequence ID" value="EEZ41952"/>
        <property type="gene ID" value="VDA_002984"/>
    </dbReference>
    <dbReference type="GeneID" id="57340704"/>
    <dbReference type="eggNOG" id="COG0261">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1949059at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01363">
        <property type="entry name" value="Ribosomal_L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036164">
        <property type="entry name" value="L21-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028909">
        <property type="entry name" value="L21p-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001787">
        <property type="entry name" value="Ribosomal_L21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018258">
        <property type="entry name" value="Ribosomal_L21_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21349">
        <property type="entry name" value="PTHR21349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00829">
        <property type="entry name" value="Ribosomal_L21p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141091">
        <property type="entry name" value="SSF141091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00061">
        <property type="entry name" value="L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01169">
        <property type="entry name" value="RIBOSOMAL_L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="103" mass="11368" checksum="7103D42BA2705455" modified="2010-01-19" version="1">MYAVFQSGGKQHRVSEGQTLRLEKLEAETGSTVEFDSVLLVANGEEVTVGAPFVAGGKVTAEVVTHGRGDKVKIVKFRRRKHSRKQMGHRQWFTEVKITGISA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0I0</accession>
    <name>D0Z0I0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Methyl-accepting chemotaxis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">VDA_003044</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the methyl-accepting chemotaxis (MCP) protein family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301677.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003044"/>
    <dbReference type="EnsemblBacteria" id="EEZ42011">
        <property type="protein sequence ID" value="EEZ42011"/>
        <property type="gene ID" value="VDA_003044"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0840">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="477199at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033479">
        <property type="entry name" value="dCache_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029151">
        <property type="entry name" value="Sensor-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02743">
        <property type="entry name" value="dCache_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103190">
        <property type="entry name" value="SSF103190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0807">Transducer</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="272"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="11">
        <location>
            <begin position="295"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="10">
        <location>
            <begin position="354"/>
            <end position="590"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ42011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="626" mass="67906" checksum="4B5D72923DD031F3" modified="2010-01-19" version="1">MRYTIKLKIQIAIGVIIATVSAVQATLSITQLRNETTQEVTNQMTAIGHATSNYIGDWLKTRSDMMLANEPLIANQDDVDRELLLTKHAGHFLSVYGGFSDGTIAYGDKTEDWPAGYDPRNRPWYQNAMKTNQLTITEPYQDFDGSLVVSLAKSFKGKKQGVLAADLTVTHIIQQVLNLKLDNDGYALLLDGNNKIVAYKDEALSQKPATQLDDELTPQLLNSLEQQQSIGTITLTNGQEKLIAVSPIAGTDWKLVVVEDKTLAYASIGEQATFVIIASIILYIIIAVIATLVINNLLRPLKDLSVSVQQLSQGNGDLTQRIDVQRMDEIGELATYMNQFLAQLQDMIQGIAKHSLSLKENADLSAQQTQQANQKVASQQNDVNQIATAIHEMSATSAEVASHAEMTASAAQASTTACEEGQQVIGENRQAITSLANQVQDAAAVIHELESNAQNINQILSTIQGIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRVLSQRTHDSTEEIRTMIDTLQQNTRQAVETMEASTGLADQSVGFAEAASESLNQITIAITEISDMATHIASAAEEQRAVSEDISRNTQAIRDVAEHLAVQTEEATESANNMSEAAAAMRTDVSRFKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0L9</accession>
    <name>D0Z0L9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidyl-prolyl cis-trans isomerase</fullName>
            <ecNumber evidence="2">5.2.1.8</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003083</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="5.2.1.8" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301809.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003083"/>
    <dbReference type="EnsemblBacteria" id="EEZ42050">
        <property type="protein sequence ID" value="EEZ42050"/>
        <property type="gene ID" value="VDA_003083"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502Z82N">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1563234at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010858">
        <property type="entry name" value="DUF1481"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016872">
        <property type="entry name" value="UCP028160"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07356">
        <property type="entry name" value="DUF1481"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028160">
        <property type="entry name" value="UCP028160"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018738" evidence="1">
        <location>
            <begin position="19"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="230" mass="25741" checksum="254050B4C0049E9B" modified="2010-01-19" version="1">MTKRIVSFLLPLLLSACAAGDNASNPTLSPIAHLTGGITQNQTTALYWLDIQQNAPLKLFEQVNTLQNGHYQSEYQWQNGVLRQMSRTGVQSYEEHMVPFSLTVRFDSKGNAIYQRYLVNKVTLPLAEPELAQISRYANEAVSVVKKQRKEGERLIQGHWQGQSFISCQTGTALPFHYQGNSKVQFTAPKQGYMALLGSQSKQGVKAKQILWSASMNQDCVMPQNMISKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0P0</accession>
    <name>D0Z0P0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nicotinamidase</fullName>
            <ecNumber evidence="2">3.5.1.19</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003104</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.5.1.19" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301870.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003104"/>
    <dbReference type="EnsemblBacteria" id="EEZ42071">
        <property type="protein sequence ID" value="EEZ42071"/>
        <property type="gene ID" value="VDA_003104"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1335">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1442962at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008936">
        <property type="term" value="F:nicotinamidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="SSF52499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase" evidence="1">
        <location>
            <begin position="5"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="212" mass="23369" checksum="31977AFB6783EEED" modified="2010-01-19" version="1">MIIAAIDVDPQQTFTPLCPNELPVHEGDTIADTLNLQASFAQYRVLTKDAHPKNALWVVDTHEEMLHPLSHPNADLTWVAHAVPGTQGFEVIPGLPKVTDYDHVIWKGIEPDLHPYGACYHDLAEELSTGLIEWLLQHKVDTLLIGGLATDYCVKTTALQFQQTNSFRVIVNLSACRGIAAETIDSAIKEMQQAGIECVHSINELSALLTNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0R5</accession>
    <name>D0Z0R5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">D-tyrosyl-tRNA(Tyr) deacylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_003129</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003129"/>
    <dbReference type="EnsemblBacteria" id="EEZ42096">
        <property type="protein sequence ID" value="EEZ42096"/>
        <property type="gene ID" value="VDA_003129"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1490">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051499">
        <property type="term" value="F:D-aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003732">
        <property type="entry name" value="Daa-tRNA_deacyls_DTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023509">
        <property type="entry name" value="DTD-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02580">
        <property type="entry name" value="Tyr_Deacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69500">
        <property type="entry name" value="SSF69500"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ42096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="57" mass="6377" checksum="0508698155498830" modified="2010-01-19" version="1">MRPSFSSGAAPADAERMYEYFVQCCKDKKIQTETGIFAADMKVALLNDGPVTFWLQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0R7</accession>
    <name>D0Z0R7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_003131</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301955.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003131"/>
    <dbReference type="EnsemblBacteria" id="EEZ42098">
        <property type="protein sequence ID" value="EEZ42098"/>
        <property type="gene ID" value="VDA_003131"/>
    </dbReference>
    <dbReference type="GeneID" id="57340641"/>
    <dbReference type="eggNOG" id="ENOG502ZBMT">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1502743at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021342">
        <property type="entry name" value="DUF2959"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11172">
        <property type="entry name" value="DUF2959"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018789" evidence="2">
        <location>
            <begin position="22"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="78"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="177"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ42098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="215" mass="24272" checksum="E200C046A4B3B984" modified="2010-01-19" version="1">MRYLLALFLTFSTLATTGCQSAYYSAMEQVGVHKRDIMVDRVESANEAQQDAQKQFTSALDALKALHKFDGGELEAAYNNINDQYQASEDAVENVNDRIDAIENVAEALFAEWQDELSLYKSATLRRDSERKLSATKAQYKKMIASMHRAEKKMEPVLDTLRDNTLYLKHNLNAAAIGSLQGEFNSLQREIQQAIRDMNAAIAESNRFISHLKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0S0</accession>
    <name>D0Z0S0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4124 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_003134</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301962.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003134"/>
    <dbReference type="EnsemblBacteria" id="EEZ42101">
        <property type="protein sequence ID" value="EEZ42101"/>
        <property type="gene ID" value="VDA_003134"/>
    </dbReference>
    <dbReference type="GeneID" id="57340637"/>
    <dbReference type="eggNOG" id="ENOG5032YZ5">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025392">
        <property type="entry name" value="DUF4124"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13511">
        <property type="entry name" value="DUF4124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019289" description="DUF4124 domain-containing protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4124" evidence="2">
        <location>
            <begin position="12"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ42101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="188" mass="20964" checksum="4F87B8AF06168B9B" modified="2010-01-19" version="1">MLRLCAVWTTTLLLLMVTNTVNATIYSWEDEHGVVHFSDRPTNPNAQEYQLDVIQVKTSQEVKQTTTQASTEAQPSKPLLPPATVSIISPIHDQTIRNNEGNIRVTAVANHPLTAQTQAQLLLDGKAYLTPQQTLTWQLENINRGTHQIQIQLIKNGKVIASSENITVYLHRASALQPKFPPVKPKTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0V4</accession>
    <name>D0Z0V4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MSHA pilin protein MshA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003168</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302060.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003168"/>
    <dbReference type="EnsemblBacteria" id="EEZ42135">
        <property type="protein sequence ID" value="EEZ42135"/>
        <property type="gene ID" value="VDA_003168"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2165">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1986406at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="225" mass="24277" checksum="47679297687CC1B9" modified="2010-01-19" version="1">MKRRYGFTLIELVVVIVIVGILAVVAAPKFLQLSHDARDADLEGLAASLRTSTETVYGKAAIVGKETLPNATVDGVAIANGYPTAKGITTTLQNTHDWHMVTVTPSDLGNWLESSMLRKIKTGLTFFTLKAYGEKGQSLKQQVKAIDAGQCYVVYVDVAHSDSSKTGNKTKNPGWFWGFVCGKILAPLGIDKYVPWCPTHQKSDANSHLNSNPTQPAIVVVDSGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0W0</accession>
    <name>D0Z0W0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD(P)H-flavin reductase</fullName>
            <ecNumber evidence="2">1.5.1.29</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003174</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.5.1.29" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302074.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003174"/>
    <dbReference type="EnsemblBacteria" id="EEZ42141">
        <property type="protein sequence ID" value="EEZ42141"/>
        <property type="gene ID" value="VDA_003174"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0543">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1834577at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="234" mass="25812" checksum="9C73E760F17C5616" modified="2010-01-19" version="1">MKCEVTSVESVACHTYKILLKPELPVEFKAGQYLLAVMGEKDKRPFSIASSPCRDGELELHIGAAEHNAYALEVVDAMKAALEQGEAISIEAPHGEAWLRADSDKPLLLVAGGTGFSYVRSILDNCLSRGFTQPIFIYWGGRDICQLYANDELQALAKQYPNVTYVPVVETAPSDWQGKIGNVLDAVEQDFVSLSDYDIYICGRFEMAGAARERFTNGKGAIRERIFADAFSFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0W7</accession>
    <name>D0Z0W7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">cAMP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003181</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302093.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003181"/>
    <dbReference type="EnsemblBacteria" id="EEZ42148">
        <property type="protein sequence ID" value="EEZ42148"/>
        <property type="gene ID" value="VDA_003181"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0664">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1596937at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="1">
        <location>
            <begin position="30"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="189" mass="22243" checksum="B22676F0745DFD31" modified="2010-01-19" version="1">MDTKFRQYLIEHQFDRTEIDNLLASASLLELPTRHILTHQGEHNQSVYFLLEGLCRASYLTADGKEFSKEFYWEHDWIIGFESVILQHPSPYLVESLTPIIVVEIPLAAVQIWRKQGHPIYLKLLENQLIHKEHKERFMLLYSPEQRYILFCQQFPDLLPRLTDQHIAAYLGISPISLSRIKARLKKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z112</accession>
    <name>D0Z112_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Glutamine--fructose-6-phosphate aminotransferase [isomerizing]</fullName>
            <ecNumber evidence="2 8">2.6.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">D-fructose-6-phosphate amidotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">GFAT</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Glucosamine-6-phosphate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Hexosephosphate aminotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">L-glutamine--D-fructose-6-phosphate amidotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">glmS</name>
        <name evidence="11" type="ORF">VDA_003226</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>D-fructose 6-phosphate + L-glutamine = D-glucosamine 6-phosphate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:13237"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58725"/>
            <dbReference type="ChEBI" id="CHEBI:61527"/>
            <dbReference type="EC" id="2.6.1.16"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.6.1.16" evidence="2 8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302217.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003226"/>
    <dbReference type="EnsemblBacteria" id="EEZ42193">
        <property type="protein sequence ID" value="EEZ42193"/>
        <property type="gene ID" value="VDA_003226"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0449">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="43416at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004360">
        <property type="term" value="F:glutamine-fructose-6-phosphate transaminase (isomerizing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901137">
        <property type="term" value="P:carbohydrate derivative biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05008">
        <property type="entry name" value="SIS_GlmS_GlmD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05009">
        <property type="entry name" value="SIS_GlmS_GlmD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00164">
        <property type="entry name" value="GlmS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035466">
        <property type="entry name" value="GlmS/AgaS_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035490">
        <property type="entry name" value="GlmS/FrlB_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005855">
        <property type="entry name" value="GlmS_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10937:SF0">
        <property type="entry name" value="PTHR10937:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01380">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01135">
        <property type="entry name" value="glmS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8 11" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 8 11" id="KW-0808">Transferase</keyword>
    <feature type="initiator methionine" description="Removed" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="9">
        <location>
            <begin position="2"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="10">
        <location>
            <begin position="285"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="10">
        <location>
            <begin position="459"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; for GATase activity" evidence="8">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <feature type="active site" description="For Fru-6P isomerization activity" evidence="8">
        <location>
            <position position="605"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ42193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="610" mass="66807" checksum="A028FC2D35CCC3D4" modified="2010-01-19" version="1">MCGIVGAVAQRDVAEILVEGLRRLEYRGYDSAGIAVIDSEHQLHRVRRLGKVQMLADALEQQPLAGGTGIAHTRWATHGEPSEANAHPHTSGDIALVHNGIIENYEALRSLLQQRGYEFQSQTDTEVIAHLVHWELAQSGSLLEAVQKTVAQLEGAYGTVVMDRRDNERVVVARSGSPLVIGLGVGENFIASDQLALLNVTRRFIFLEEGDVAEITRRDIAIFDEAGQAVQREIHESTVEHDAADKGQYRHYMQKEIYEQPSALINTMEGRIRNNSVVVESIGTGAKEILNKVEHIQIVACGTSYNAGMVARYWFEAMTGVSCDVEIASEFRYRKFVTRPNSLLITLSQSGETADTLAALRLAKEKGYMAAMTICNVAGSSLVRESDLAFMTRAGAEIGVASTKAFTTQLIALLMLVTALGKEKGAIDSELEAKIVHAMQQLPSYIEKALAFDKPIEALAEDFADKHHALFLGRGEFYPIAVEASLKLKEISYIHAEAYAAGELKHGPLALIDADMPVIVVAPTNDLLEKLKSNIEEVRARGGLLYVFADNEAGFEASEGMKIITMPKVDEIIAPIFYTIPMQLLSYHVALIKGTDVDQPRNLAKAVTVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z136</accession>
    <name>D0Z136_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 12">DNA gyrase subunit B</fullName>
            <ecNumber evidence="4 12">5.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">gyrB</name>
        <name evidence="14" type="ORF">VDA_003250</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="12">Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="12">Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the type II topoisomerase GyrB family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the type II topoisomerase family.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="4 12"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003250"/>
    <dbReference type="EnsemblBacteria" id="EEZ42217">
        <property type="protein sequence ID" value="EEZ42217"/>
        <property type="gene ID" value="VDA_003250"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0187">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003918">
        <property type="term" value="F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03366">
        <property type="entry name" value="TOPRIM_TopoIIA_GyrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.670">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01898">
        <property type="entry name" value="GyrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002288">
        <property type="entry name" value="DNA_gyrase_B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011557">
        <property type="entry name" value="GyrB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041423">
        <property type="entry name" value="GyrB_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001241">
        <property type="entry name" value="Topo_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013760">
        <property type="entry name" value="Topo_IIA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013759">
        <property type="entry name" value="Topo_IIA_B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013506">
        <property type="entry name" value="Topo_IIA_bsu_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018522">
        <property type="entry name" value="TopoIIA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034160">
        <property type="entry name" value="TOPRIM_GyrB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00204">
        <property type="entry name" value="DNA_gyraseB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00986">
        <property type="entry name" value="DNA_gyraseB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18053">
        <property type="entry name" value="GyrB_insert"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01751">
        <property type="entry name" value="Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00433">
        <property type="entry name" value="TOP2c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56719">
        <property type="entry name" value="SSF56719"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01059">
        <property type="entry name" value="gyrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00177">
        <property type="entry name" value="TOPOISOMERASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11 12 14" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 12" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="Toprim" evidence="13">
        <location>
            <begin position="408"/>
            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEZ42217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="793" mass="88549" checksum="86AFD835E29736A5" modified="2010-01-19" version="1">MLKGLDAVRKRPGMYIGDTDDGTGLHHMVFEVVDNSIDEALAGHCEDIVVTICEDGSVSVSDDGRGIPTELHPEEGVSAAEVIMTVLHAGGKFDDNSYKVSGGLHGVGVSVVNALSEKVELTIYRHGHIHRQIYRHGVPQAPLEVIGDTDRTGTTIRFWPSSETFTNTTFQYEILAKRLRELSFLNSGVSIKLNDEREEGKQDHFMYEGGIQAFVEHLNRNKTPIHQKVFHFNVEREDGITVEVAMQWNDGFQENIYCFTNNIPQRDGGTHLAGFRGALTRTLNNYMEKEGYSKKAKAATSGDDAREGLTAVISVKVPDPKFSSQTKDKLVSSEVKSAVESTMGEKLGEFLLENPGDAKTVCTKIIDASRAREAARKAREMTRRKGALDLAGLPGKLADCQEKDPALSELYIVEGDSAGGSAKQGRNRKNQAILPLKGKILNVEKARFDKMLSSQEVATLITAMGCGIGRDEYNPDKLRYHSIIIMTDADVDGSHIRTLLLTFFYRQMPELIERGHIYIAQPPLYKVKKGKQEQYIKDDEDMQQFQTSLALENAALFTTEGAPAMAGLALENLVGQYNSTMKLIERMSRRYPTLLLNELVHQPRLTAEMLSDRAQVEAWVTPVIEALNAKQSGESHYTFDIVVDSENNHFLPKVVVRTHGVDHEYPLSFELICSKEYSKLADLSEVLNGLLDDSAYVQRGERKQPVASFKEVLEWLNKESRRGLSLQRYKGLGEMNPDQLWETTMDPESRRMMRVTINDAVAADELFTTLMGDQVEPRRNFIEANALNANLDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z155</accession>
    <name>D0Z155_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative cytochrome c5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_003269</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003269"/>
    <dbReference type="EnsemblBacteria" id="EEZ42236">
        <property type="protein sequence ID" value="EEZ42236"/>
        <property type="gene ID" value="VDA_003269"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3245">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002323">
        <property type="entry name" value="Cyt_CIE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40942">
        <property type="entry name" value="PTHR40942"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13442">
        <property type="entry name" value="Cytochrome_CBB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00607">
        <property type="entry name" value="CYTCHROMECIE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0249">Electron transport</keyword>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Cytochrome c" evidence="6">
        <location>
            <begin position="6"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ42236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="61" mass="6599" checksum="0D022F6A7DF7A5A5" modified="2010-01-19" version="1">MNAPKKGDAADWKDRLAQGQEILAKHAIEGFNAMPAKGSCMDCSDEEIIAAINYMTEGLTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z169</accession>
    <name>D0Z169_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Sec-independent protein translocase protein TatA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">tatA</name>
        <name evidence="9" type="ORF">VDA_003283</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the TatA/E family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302381.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003283"/>
    <dbReference type="EnsemblBacteria" id="EEZ42250">
        <property type="protein sequence ID" value="EEZ42250"/>
        <property type="gene ID" value="VDA_003283"/>
    </dbReference>
    <dbReference type="GeneID" id="57340284"/>
    <dbReference type="eggNOG" id="COG1826">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033281">
        <property type="term" value="C:TAT protein transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043953">
        <property type="term" value="P:protein transport by the Tat complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00236">
        <property type="entry name" value="TatA_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003369">
        <property type="entry name" value="TatA/B/E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006312">
        <property type="entry name" value="TatA/E"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02416">
        <property type="entry name" value="TatA_B_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01411">
        <property type="entry name" value="tatAE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0811">Translocation</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ42250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="86" mass="9464" checksum="B879BE54EC04DC6D" modified="2010-01-19" version="1">MGGISIWQLLIIALIIVLLFGTKKLRTLGGDLGSAVKGFKKAISDEDDTTAKKTAADDADFEQKKLTEEKQQAENVQKDQKDKEQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z174</accession>
    <name>D0Z174_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Arginine decarboxylase catabolic</fullName>
            <ecNumber evidence="7">4.1.1.19</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_000298</name>
        <name evidence="7" type="ORF">VDA_003288</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Orn/Lys/Arg decarboxylase class-I family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.19" evidence="7"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000298"/>
    <dbReference type="EnsemblBacteria" id="EEZ39280">
        <property type="protein sequence ID" value="EEZ39280"/>
        <property type="gene ID" value="VDA_000298"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ42255">
        <property type="protein sequence ID" value="EEZ42255"/>
        <property type="gene ID" value="VDA_003288"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1982">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008792">
        <property type="term" value="F:arginine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005308">
        <property type="entry name" value="OKR_de-COase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011193">
        <property type="entry name" value="Orn/lys/arg_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000310">
        <property type="entry name" value="Orn/Lys/Arg_deCO2ase_major_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008286">
        <property type="entry name" value="Prn/Lys/Arg_de-COase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036633">
        <property type="entry name" value="Prn/Lys/Arg_de-COase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01276">
        <property type="entry name" value="OKR_DC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03711">
        <property type="entry name" value="OKR_DC_1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03709">
        <property type="entry name" value="OKR_DC_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009393">
        <property type="entry name" value="Orn_decarb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55904">
        <property type="entry name" value="SSF55904"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00703">
        <property type="entry name" value="OKR_DC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OKR_DC_1" evidence="5">
        <location>
            <begin position="382"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="53"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="3">
        <location>
            <position position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR009393-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ39280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ42255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="759" mass="84834" checksum="9578CAE163B9C096" modified="2010-01-19" version="1">MRALIVEHQNIEANSYADRTTQSLAQELKDRSIEIITATSYDDAKAIIMANQIDSLVLALDKTEEQLTNSTEELELLAVLKERQAEVPVFVLAERARTSVLANRKLMERIDECYSVLEDTADFVAGRIVAAMKRYRDVVIPPFMKAMMEYNDVHEYSWSAPGHQGGIGFTKTPAGNQFYQFYGENLFRTDMGIERASLGSLLDHTGAFKDSEVEAAKIFGAHESYSGIVGTSGSNRTIMQACLKDDDVAICDRNCHKSIEQGLILTGARPVYMTPSRNCYGIIGPISKAQMSKESLAKKIAEKAPEFDLNKDKASYSVVTNCTYDGMCYHSEVTEALLAESASRIHMDEAWFGYARFNPIYKGHFAMRGDAKDHKGPTVFATHSTHKLLNALSQASYIHVRNGENAIDFDRFNQAYMMHTSTSPLYAICASNDVAANMMKGESGLSLTNEVVREAVIFRQNVRRLFNDYTSENDWFFKPWNAETVTETNGDKVKFEDASVEALMTVQDNWKLHPGDQWHGFDDIDDDWCMLDPIKVSLLTPGLDDKGQFLDKGVPAALVSAYLGRFGIVPTRTTDFQVMFLFSMGITKGKRDTLINTLLSFKRHYDANADLEVILPELVASNPAAYKGLGLKDLGNKMFEYLVRHNPGQVLNNAYSSLPEMELKPRDAYQMIVSNDVELVASDELVGRVAAHSVIPYPPGIPMLMGGENFGDENSPQIQYLKALEAWDEEFPGFEHETEGAEIENGKYHVLCIKKDALK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1A8</accession>
    <name>D0Z1A8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_003322</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302489.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003322"/>
    <dbReference type="EnsemblBacteria" id="EEZ42289">
        <property type="protein sequence ID" value="EEZ42289"/>
        <property type="gene ID" value="VDA_003322"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1999">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1720650at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ42289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="196" mass="21965" checksum="B4C6C433CFF49CC1" modified="2010-01-19" version="1">MAKQRKSYLSIFGLIMAFLLPIALAKVMLEKKWYQGGVTNKGSLVAQPITIPQLQQDARWQLIYLLPNECQLACLGALFTLQQVPQAIGPERDRVISKVYVSRETSLADINQKIKLSELFQIQSLQNYQFSVLPSFPKLEQALSQLQFAGIGLYLIDPLGNIMMAYPLASEKTAILAQGKDVLRDLKRLLKVSKIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1H6</accession>
    <name>D0Z1H6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 8">50S ribosomal protein L31</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rpmE</name>
        <name evidence="9" type="ORF">VDA_003390</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Binds the 23S rRNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 8">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302627.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003390"/>
    <dbReference type="EnsemblBacteria" id="EEZ42357">
        <property type="protein sequence ID" value="EEZ42357"/>
        <property type="gene ID" value="VDA_003390"/>
    </dbReference>
    <dbReference type="GeneID" id="57340160"/>
    <dbReference type="eggNOG" id="COG0254">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2014569at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.830.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00501">
        <property type="entry name" value="Ribosomal_L31_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034704">
        <property type="entry name" value="L28p-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002150">
        <property type="entry name" value="Ribosomal_L31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027491">
        <property type="entry name" value="Ribosomal_L31_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042105">
        <property type="entry name" value="Ribosomal_L31_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33280">
        <property type="entry name" value="PTHR33280"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01197">
        <property type="entry name" value="Ribosomal_L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01249">
        <property type="entry name" value="RIBOSOMALL31"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143800">
        <property type="entry name" value="SSF143800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00105">
        <property type="entry name" value="L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01143">
        <property type="entry name" value="RIBOSOMAL_L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 8 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 8" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="8">
        <location>
            <position position="16"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="18"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="37"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ42357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="70" mass="7760" checksum="EA92F951D5F379AE" modified="2010-01-19" version="1">MKQGIHPEYTAVNARCSCGNTFAFNSTLGKDINLDVCDKCHPFYTGKQRQVSTGGRIDKFNKRFGALSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1N0</accession>
    <name>D0Z1N0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8 11">50S ribosomal protein L22</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rplV</name>
        <name evidence="12" type="ORF">VDA_003444</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.</text>
    </comment>
    <comment type="function">
        <text evidence="7">This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.</text>
    </comment>
    <comment type="function">
        <text evidence="8 11">This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8 10">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8 9">Belongs to the universal ribosomal protein uL22 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302797.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003444"/>
    <dbReference type="EnsemblBacteria" id="EEZ42411">
        <property type="protein sequence ID" value="EEZ42411"/>
        <property type="gene ID" value="VDA_003444"/>
    </dbReference>
    <dbReference type="GeneID" id="61231775"/>
    <dbReference type="eggNOG" id="COG0091">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1666043at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00336">
        <property type="entry name" value="Ribosomal_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01331_B">
        <property type="entry name" value="Ribosomal_L22_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001063">
        <property type="entry name" value="Ribosomal_L22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018260">
        <property type="entry name" value="Ribosomal_L22/L17_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036394">
        <property type="entry name" value="Ribosomal_L22/L17_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005727">
        <property type="entry name" value="Ribosomal_L22_bac/chlpt-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13501">
        <property type="entry name" value="PTHR13501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00237">
        <property type="entry name" value="Ribosomal_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54843">
        <property type="entry name" value="SSF54843"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01044">
        <property type="entry name" value="rplV_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00464">
        <property type="entry name" value="RIBOSOMAL_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 8 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 8 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 8 10" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ42411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="110" mass="12179" checksum="C2BEB7737723EC69" modified="2010-01-19" version="1">MEAIAKHRFARISPQKARLVADQLRGKPVAQALEILNFSNKKAADLIKKVLESAIANAEHNEGADIDDLNVAKIFVDEGPTMKRIMPRAKGRADRILKRSSHITVVVADR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1T5</accession>
    <name>D0Z1T5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MSHA pilin protein MshB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003499</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303615.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003499"/>
    <dbReference type="EnsemblBacteria" id="EEZ42466">
        <property type="protein sequence ID" value="EEZ42466"/>
        <property type="gene ID" value="VDA_003499"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4968">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1765531at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="200" mass="21336" checksum="70B46B0A6ADC09E9" modified="2010-01-19" version="1">MNKQQGFSLIELVIVIIVVGILAATAMPRFLNITEQAKKAAVEGMAGGYATAVISARAQWEAYGRPTMQGVSGAVNSVDYDGSEFLLTKASNQDGVRMGYPYALSIDGSSKPFSAMAPQDCVDLLENLLQNPPRASLDQQSIPSGNNVFFVSMLGSGSEKACRYYQTTSAKNSSGIADITTGHYFTYTPATGRVEVNINN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1V5</accession>
    <name>D0Z1V5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Lipopolysaccharide export system protein LptC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">lptC</name>
        <name evidence="8" type="ORF">VDA_003519</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA.</text>
    </comment>
    <comment type="function">
        <text evidence="7">Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the lipopolysaccharide transport and assembly complex. Interacts with LptA and the LptBFG transporter complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell inner membrane</location>
            <topology evidence="6">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the LptC family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303677.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003519"/>
    <dbReference type="EnsemblBacteria" id="EEZ42486">
        <property type="protein sequence ID" value="EEZ42486"/>
        <property type="gene ID" value="VDA_003519"/>
    </dbReference>
    <dbReference type="GeneID" id="57340006"/>
    <dbReference type="eggNOG" id="COG3117">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1983716at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015221">
        <property type="term" value="F:lipopolysaccharide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043165">
        <property type="term" value="P:Gram-negative-bacterium-type cell outer membrane assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01915">
        <property type="entry name" value="LPS_assembly_LptC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010664">
        <property type="entry name" value="LipoPS_assembly_LptC-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026265">
        <property type="entry name" value="LptC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06835">
        <property type="entry name" value="LptC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028513">
        <property type="entry name" value="LptC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04409">
        <property type="entry name" value="LptC_YrbK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6 7" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1 6 7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR028513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ42486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="187" mass="21149" checksum="2FDED19A0CA471E6" modified="2010-01-19" version="1">MTLKRLCYLLVVLVAVWSGYYLLQKHWQSDDQVTIDSEKPVFTGDVVSNTSYNEKGIRSYQIDSAHIEHFSISGNTTFSKPVLWVYQDGSKTEWRVSANDALLTQDQVLEMKGNVRIFNLLPESAIQVISTDNLRLNLVNKDFDTQDHVVITGTSFENEGDGLKGNMDRNVATLLNNVKGIYETPKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1V6</accession>
    <name>D0Z1V6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 8">3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC</fullName>
            <ecNumber evidence="5 8">3.1.3.45</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7 8">KDO 8-P phosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_003520</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>3-deoxy-alpha-D-manno-2-octulosonate-8-phosphate + H2O = 3-deoxy-alpha-D-manno-oct-2-ulosonate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:11500"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:85985"/>
            <dbReference type="ChEBI" id="CHEBI:85986"/>
            <dbReference type="EC" id="3.1.3.45"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 8 9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4 8">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the KdsC family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.45" evidence="5 8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303680.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003520"/>
    <dbReference type="EnsemblBacteria" id="EEZ42487">
        <property type="protein sequence ID" value="EEZ42487"/>
        <property type="gene ID" value="VDA_003520"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1778">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1232828at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019143">
        <property type="term" value="F:3-deoxy-manno-octulosonate-8-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009103">
        <property type="term" value="P:lipopolysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006549">
        <property type="entry name" value="HAD-SF_hydro_IIIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010023">
        <property type="entry name" value="KdsC_fam"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006118">
        <property type="entry name" value="KDO8-P_Ptase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01138">
        <property type="entry name" value="C1.6.2:_Deoxy-d-mannose-octulo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01662">
        <property type="entry name" value="HAD-SF-IIIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01670">
        <property type="entry name" value="KdsC-phosphatas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0448">Lipopolysaccharide biosynthesis</keyword>
    <keyword evidence="8 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="9">
        <location>
            <position position="29"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00020092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00031051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR006118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR006118-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ42487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="185" mass="20419" checksum="B77B52EDA3C1D503" modified="2010-01-19" version="1">MSQLVETIYGSVSQNVFNQAKQIQLLICDVDGVFSDGRIYMGNNGEELKTFHTRDGYGVKSLMNAGIQVAIITGRRSNIVENRMQALGIEHIYQGQDNKLTAYQDIIDKLAIEPQHIAYIGDDLIDWPVMAKIGLSVCVADGHPLLAQRADFITRIQGGYGAVREVCDLILEAKGELDKHKGLSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1X5</accession>
    <name>D0Z1X5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Phosphoheptose isomerase</fullName>
            <ecNumber evidence="10">5.3.1.28</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Sedoheptulose 7-phosphate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">gmhA</name>
        <name evidence="12" type="ORF">VDA_003539</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 10">Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>2 D-sedoheptulose 7-phosphate = D-glycero-alpha-D-manno-heptose 7-phosphate + D-glycero-beta-D-manno-heptose 7-phosphate</text>
            <dbReference type="Rhea" id="RHEA:27489"/>
            <dbReference type="ChEBI" id="CHEBI:57483"/>
            <dbReference type="ChEBI" id="CHEBI:60203"/>
            <dbReference type="ChEBI" id="CHEBI:60204"/>
            <dbReference type="EC" id="5.3.1.28"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="10">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="10">Carbohydrate biosynthesis; D-glycero-D-manno-heptose 7-phosphate biosynthesis; D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate from sedoheptulose 7-phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="10">The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the SIS family. GmhA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.28" evidence="10"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303734.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003539"/>
    <dbReference type="EnsemblBacteria" id="EEZ42506">
        <property type="protein sequence ID" value="EEZ42506"/>
        <property type="gene ID" value="VDA_003539"/>
    </dbReference>
    <dbReference type="GeneID" id="57339983"/>
    <dbReference type="eggNOG" id="COG0279">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1571626at2"/>
    <dbReference type="UniPathway" id="UPA00041">
        <property type="reaction ID" value="UER00436"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008968">
        <property type="term" value="F:D-sedoheptulose 7-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001061">
        <property type="term" value="P:D-glycero-D-manno-heptose 7-phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd05006">
        <property type="entry name" value="SIS_GmhA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00067">
        <property type="entry name" value="GmhA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035461">
        <property type="entry name" value="GmhA/DiaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004515">
        <property type="entry name" value="Phosphoheptose_Isoase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13580">
        <property type="entry name" value="SIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 10 12" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="SIS" evidence="11">
        <location>
            <begin position="34"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="49"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="91"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="117"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="172"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ42506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="196" mass="20909" checksum="A368A03B8890069B" modified="2010-01-19" version="1">MLDSIRESFTESIQTQIAAAEALPDAIAKAAQVMVQSLLNGNKILCCGNGGSAANAQHFASCLINRFETERPSLPALALTADTTILTAVANDYSGDQVFSKQVRALGQAGDVLFVLSTSGNSKNIIKAMEAALTRDMTIIALTGKDGGEMAGLLGTHDVEIRIPSQRTARIQEVHLLTIHTLCDLIDRVLFPYHEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1Y4</accession>
    <name>D0Z1Y4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Molybdopterin biosynthesis protein B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001974</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299062.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001974"/>
    <dbReference type="EnsemblBacteria" id="EEZ40942">
        <property type="protein sequence ID" value="EEZ40942"/>
        <property type="gene ID" value="VDA_001974"/>
    </dbReference>
    <dbReference type="GeneID" id="57341886"/>
    <dbReference type="eggNOG" id="COG0476">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1408716at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008641">
        <property type="term" value="F:ubiquitin-like modifier activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012730">
        <property type="entry name" value="Mopterin_Synthase_Sase_MoeB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="PTHR10953"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="SSF69572"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02355">
        <property type="entry name" value="moeB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ThiF" evidence="1">
        <location>
            <begin position="12"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="252" mass="27566" checksum="39E8541FCA50AD42" modified="2010-01-19" version="1">MSELSDAEMLRYNRQIMLRQFDFEGQEALKSASMLILGAGGLGCASTQYLAAAGVGKLTLIDDDKVEVSNLQRQLLHNDSTIGQLKVESAKTALEKINPYLEVETIAKRLSDDELRPLIEQHDLVLDCSDNVDTRNQLNRLCFAIKKPLISGAAIRMEGQISVYTYQDNEPCYQCLSALFGQQTLSCVEAGIMSPVVGIVGAVQAMEAIKVVSHMGTPLTGKLLMLDALSMSWREMKLMKLPTCSVCGTQSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z257</accession>
    <name>D0Z257_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hypothetical Ap4A phosphorylase II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001793</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298711.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001793"/>
    <dbReference type="EnsemblBacteria" id="EEZ40761">
        <property type="protein sequence ID" value="EEZ40761"/>
        <property type="gene ID" value="VDA_001793"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4360">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1314021at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003877">
        <property type="term" value="F:ATP adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009163">
        <property type="entry name" value="Ap4A_phos1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043171">
        <property type="entry name" value="Ap4A_phos1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045759">
        <property type="entry name" value="Ap4A_phos1/2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019200">
        <property type="entry name" value="ATP_adenylylTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38420">
        <property type="entry name" value="PTHR38420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19327">
        <property type="entry name" value="Ap4A_phos_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09830">
        <property type="entry name" value="ATP_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000846">
        <property type="entry name" value="ATP_adenylyltr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="SSF54197"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ap4A_phos_N" evidence="3">
        <location>
            <begin position="2"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="ATP_transf" evidence="2">
        <location>
            <begin position="158"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000846-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF19327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="268" mass="30599" checksum="712A911DD122C115" modified="2010-01-19" version="1">MFWEQAEQVIEQAKANGSLYPIATEAVAIEQNGITYLGHIVAKNSAQRKFTPKPTADFNPFFPYEQDMFVAEAGEEHVCLLNKFPVITPHLLICSKQFISQESPLELEDFAAWLRGFESDNVLGFYNGGPVAGASQAHRHMQLVQSEVPLEALILSERLPFEHRLYRYHRPSSEKLYISYLAAMREMKLFGSEENNNKCKPYNILLTRHWMLVIPRSRNCIEDIFANGMNYSGRFLVKNAEQLEWLKTHGLLNLLQACAIAKDLGDEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z265</accession>
    <name>D0Z265_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Anaerobic sulfite reductase subunit C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_001912</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298921.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001912"/>
    <dbReference type="EnsemblBacteria" id="EEZ40880">
        <property type="protein sequence ID" value="EEZ40880"/>
        <property type="gene ID" value="VDA_001912"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2221">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1128731at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.413.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005117">
        <property type="entry name" value="NiRdtase/SiRdtase_haem-b_fer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036136">
        <property type="entry name" value="Nit/Sulf_reduc_fer-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006067">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045169">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045854">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006066">
        <property type="entry name" value="NO2/SO3_Rdtase_FeS/sirohaem_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014261">
        <property type="entry name" value="Sulphite_reductase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11493">
        <property type="entry name" value="PTHR11493"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01077">
        <property type="entry name" value="NIR_SIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03460">
        <property type="entry name" value="NIR_SIR_ferr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00397">
        <property type="entry name" value="SIROHAEM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55124">
        <property type="entry name" value="SSF55124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56014">
        <property type="entry name" value="SSF56014"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02912">
        <property type="entry name" value="sulfite_red_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="7">
        <location>
            <begin position="171"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="7">
        <location>
            <begin position="203"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ40880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="336" mass="37478" checksum="A67C56D8F5C4777C" modified="2010-01-19" version="1">MDLDVDIIKTRANGDYRLSKVRGECMISVRIPGGIMPAHLLSVAQYIAQEFGNGIIHLTTRQKLAMPGIKYQDIDKVNKALEPFLQEITVEQCGIDVEDTQAGYKSIAGRNIVACQGSRICQKANTDTTGLALRLEHHIYPQPYHLKIVLAGCPNDCAKANMADFGVLGVAKMHFNAERCIGCGACVRACEHHAVGCLSLKNGKAIKEESKCIGCGECVLACPTLAWQRDPKQLYMVKLGGRTSKKTPRTGKMFLNWVTEDVLHQVIENLLGFEKEMLEGKPVYLHMGHLIDRAGYHKFKERVLRNVELNPEAQVAERIYWVEDEYVANMHVRSAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2E4</accession>
    <name>D0Z2E4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">VWFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000595</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304814.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000595"/>
    <dbReference type="EnsemblBacteria" id="EEZ39575">
        <property type="protein sequence ID" value="EEZ39575"/>
        <property type="gene ID" value="VDA_000595"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2425">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="576118at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008912">
        <property type="entry name" value="Uncharacterised_CoxE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05762">
        <property type="entry name" value="VWA_CoxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="1">
        <location>
            <begin position="321"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="485" mass="56001" checksum="2ACBA0798C5A7FB1" modified="2010-01-19" version="1">MPLTEGLNLALMLAESGMIDSAVNEIMVRPQLLMAAEATPGIKASIQNQMLKWRAQMTRNLSKVSISENIQQEFKFYEQAKDWDEETFLAKSGDIVKSLEGRSNFYFKAKRLVDADHHKHNPMFQRYFCDQWYEHLVQALKDVQESELTDAKDELLRDLYQRIETMQQMKEVADEGDEKRAGRLWDMAKAKLTRTDVDTMKSIAKFLKKNQGLQEIAEKLGRMASEIDDPTKERVKVEELKLVEEQSDNVTDDIVGIHESDDLAKLLPNEAMFLAYPELEVVFYKHLVDKRLMNYRVRGTNRKLRKVKSFKRQSKQVEQDKGPFIVCIDASGSMSGFPENCAKALAYGLMQIALADDRDCFVIMFSTQQITYELTKQDGLKEMINFLSYSFHGGTDLAPVLDQSIDLMGSEKYKNADLVVLSDFIAPSQPEEMQKRVAKLKEQRNRFHAVSLSKYGNPELLEMFDFCWSYHPSTFSQFGKLFRWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2L0</accession>
    <name>D0Z2L0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000661</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000661"/>
    <dbReference type="EnsemblBacteria" id="EEZ39641">
        <property type="protein sequence ID" value="EEZ39641"/>
        <property type="gene ID" value="VDA_000661"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="38" mass="4243" checksum="74F8D0C7B3E55339" modified="2010-01-19" version="1">MDVVTLSITEFEQKIAANQIQDNKTLAAYCKAKAMQLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2V1</accession>
    <name>D0Z2V1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000752</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305249.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000752"/>
    <dbReference type="EnsemblBacteria" id="EEZ39732">
        <property type="protein sequence ID" value="EEZ39732"/>
        <property type="gene ID" value="VDA_000752"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3385">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1254910at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024473">
        <property type="entry name" value="Transposases_IS4_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13006">
        <property type="entry name" value="Nterm_IS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nterm_IS4" evidence="3">
        <location>
            <begin position="17"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="DDE_Tnp_1" evidence="2">
        <location>
            <begin position="125"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="416"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="435" mass="50041" checksum="F1560496EAA5554D" modified="2010-01-19" version="1">MDVSQALNVINNWKSDNIETLSDLLPIELIDEAYSLTDTVTMRKRKLTLESMVWLLVGMAIYNNKSMKDLVNQLDIVDRTGKAFVAPSALTQRRKTLGEDAIKAVFERMTNSWLKSANLPHWNGLTLLSVDGVVWRTPDNQENEEAFSRQKGTQYPQVRMVCQMELSSHLITASAFDNYNTNEMVLAEKLIETTPDHSVTMFDKGFYSLGLLDKGHTTGTERHWLIPLKKNVQYEVIRPLGRNDKLILLHSNPRARKLWPNLPSSITARLVTRKIKGKDYQVLTSMIDPLRYPSNDIAALYEHRWEIELGYREQKQYMLGNRLTLRSRLPELVRQELWGILLTYNLIRYQMVELCFNLKGNYLPYQLSFNGTLAHVSALLVGLPYSSPGAIPRQLKGFHAMAESLILEGRRERSFPRAVKPRPQRYPKKKNAVHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2Y0</accession>
    <name>D0Z2Y0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Periplasmic alpha-amylase</fullName>
            <ecNumber evidence="7">3.2.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_000781</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="2">Binds 1 Ca(2+) ion per subunit.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.1" evidence="7"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305332.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000781"/>
    <dbReference type="EnsemblBacteria" id="EEZ39761">
        <property type="protein sequence ID" value="EEZ39761"/>
        <property type="gene ID" value="VDA_000781"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="148706at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004556">
        <property type="term" value="F:alpha-amylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030980">
        <property type="term" value="P:alpha-glucan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051692">
        <property type="term" value="P:cellular oligosaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014635">
        <property type="entry name" value="A_amylase_MalS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036917">
        <property type="entry name" value="Alph_amls_MalS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019952" evidence="5">
        <location>
            <begin position="21"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="domain" description="Aamy" evidence="6">
        <location>
            <begin position="204"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="464"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="505"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="325"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="468"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="3">
        <location>
            <position position="570"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="4">
        <location>
            <begin position="131"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR036917-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR036917-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR036917-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR036917-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="688" mass="78283" checksum="0E281D7B6FE470F4" modified="2010-01-19" version="1">MKINLLIVLISALSSSAVIANPSLTISTSTTSRDYPLSDLQSLVIPLVKGEYQLKIEGINKDCQSPIVKKIRFNQPLNLNCSKPTVLPIKIRFSGDYAFEYDGKKQTVLIKRAPKKQTHSVFKRPIPQIDCEQYHGGLVTLDLANTYPDGTQLREVFTQQNVVVNNGKVRLTPSINSAGLVLLEPLTQVEPKPSFNYRNANIYFVMLDRFNNGDTRNDNSYGRHKDGKQEIGTFHGGDIQGVIDKLDYIQSLGTNVIWLSPIVEQVHGFVGGGDSGSFPFYAYHGYWTRDFTKIDANLGNEAELRELVSQAHQRGIKVLLDAVINHAGYATLADLQFDDIQVVNREQVPKQWADWQPKAGQSWHSYNSLINYQSKEWQQWWGKDWVRAGLPDYLAPGSDDITMTLAGLPDFLTESEKVVTPPQWLLDNPDTQVKAKPNYTVSDYLIEWQTDWVKRFGIDGFRVDTVKHVDGEVWQRLKLQAGEKLQQWRQLHNSKNNEPFWMMGEVWGHGAYRSPYYNDGFDALINFDLQKKMDQAAVCFSQMKPVYQDYNQQLKKSADFNMTSYISSHDTELFFSRYRSFEMQKSAANALLLSPGAVQVFYGDEIGRDLGPYADDFHQGTRSDMVWKLNDEQQALLQHWRTVGQFRQRHPAVGAGVHQELTQQQGYAFSRQLGTDKVVVAFVGNPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2Z7</accession>
    <name>D0Z2Z7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytosine/purine/uracil/thiamine/allantoin permease family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_000798</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the purine-cytosine permease (2.A.39) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305380.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000798"/>
    <dbReference type="EnsemblBacteria" id="EEZ39778">
        <property type="protein sequence ID" value="EEZ39778"/>
        <property type="gene ID" value="VDA_000798"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="326558at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015209">
        <property type="term" value="F:cytosine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030191">
        <property type="entry name" value="CodB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001248">
        <property type="entry name" value="Pur-cyt_permease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30569">
        <property type="entry name" value="PTHR30569"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02133">
        <property type="entry name" value="Transp_cyt_pur"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="52"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="95"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="130"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="193"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="222"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="258"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="299"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="324"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="360"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="413" mass="43247" checksum="FC567DD30A3F961E" modified="2010-01-19" version="1">MASDNNYSLGPVPLSARKGALSLTMVMLGLTFFSASMWTGGTLGTGLSYHDFFLAVAIGNLILGIYTSFLGYIGASTGLSTHLLARFSFGLKGSWLPSSLLGGTQVGWFGVGVAMFAIPVHKATGIDTNILILVSGLLMTATVYFGIAALMILSAIAVPAIALLGGYSVIEAVNSIGGVEQLKLISPETPLEFSTALVLVVGSFVSAGTLTADFVRFGRKPIMAVVITMIAFFLGNSLMFIFGAAGGAVTGQSDISEVMIAQGLLIPAIIVLGLNIWTTNDNALYASGLGFSNITKLPSKHLSVINGIIGTLCALWLYNHFVGWLTFLSAAIPPIGGIIIADFLKNRHRYHDFANAKFQTVNWAAIIGVAIGVACGHFIPGIVPINAVLGGAISYLILNPIINRNTQFQPVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3G7</accession>
    <name>D0Z3G7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Oxidoreductase short-chain dehydrogenase/reductase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000968</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305863.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000968"/>
    <dbReference type="EnsemblBacteria" id="EEZ39948">
        <property type="protein sequence ID" value="EEZ39948"/>
        <property type="gene ID" value="VDA_000968"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1356861at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="222" mass="23627" checksum="59895E8921F46A4B" modified="2010-01-19" version="1">MKTEKTVYVVLGGTSGIGAELSQQLANDNSIIHVASRKTGLDISDEQSVYHYFETIGAFDHLIVTAGSYAPAGKVVDVDVSQAKYAFDTKFWGAINAAKHGARYIKKGGSITLTSGMLSRKVVANTYVKTAINAAIEATTKILAKELAPIRVNAVSPGLTRTEAYQGMSEDDRNAMYQRTQNSLPVGKVGEASDVAKAYRLLIENSYMTGAVIDVDGGALLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3H5</accession>
    <name>D0Z3H5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ribosomal large subunit pseudouridine synthase A</fullName>
            <ecNumber evidence="3">4.2.1.70</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000976</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="4.2.1.70" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305887.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000976"/>
    <dbReference type="EnsemblBacteria" id="EEZ39956">
        <property type="protein sequence ID" value="EEZ39956"/>
        <property type="gene ID" value="VDA_000976"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0564">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1714699at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140098">
        <property type="term" value="F:catalytic activity, acting on RNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004730">
        <property type="term" value="F:pseudouridylate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034470">
        <property type="term" value="P:ncRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd02869">
        <property type="entry name" value="PseudoU_synth_RluA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006224">
        <property type="entry name" value="PsdUridine_synth_RluC/D_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01129">
        <property type="entry name" value="PSI_RLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PseudoU_synth_2" evidence="2">
        <location>
            <begin position="366"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="116"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="216"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="560" mass="64011" checksum="285ABE31DB6FE727" modified="2010-01-19" version="1">MHSPQSCFTRFQSSIDQYTLPERFTFPFYYTPHPLCELAAQELQLHLETQTQWQHNFGLNGDLDTAIGKMFGVLLVKNADGEIGYLSAFSGKIADQNLLPHFVPPVFDMLTDDGFFQAEQKVINDVTAEIRQLETNAELLALRDTFAQSQAQAADEIEQCRLQIIDSRKDRKEQRKAAEATNDSQLIEETAIRLAKESAKQKHEQRFLKSTWDEKLQVLANQVDVFDNEINELKEKRRHLSSTLQAKLFAQYRFLNQYGEEKDLIDIFAQTPNQTPPAGSGECAAPKLLHYAFKHGMTPIAMAEFWWGASPKSEIRKHKYFYEACKSKCEPILGHMLKGIELEENLLLKNPAEGKELEIIYQDEAMVIVNKPAEFLSVPGKTISDSVYTRMQAMFPDADSPLIVHRLDMSTSGLLVIALTKRAHKNLQKQFITRTVEKRYVALLDGLADSDEGIISLPMRGDINDRPRQLVCFEHGKPAETKWQVISRKDGKTKVYYYPKTGRTHQLRVHSAHPMGMNMPIIGDDLYGQKSNRLHLHAEYLSLEHPITHEPMEFQVDAEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3I1</accession>
    <name>D0Z3I1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Oxidored_FMN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000982</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305904.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000982"/>
    <dbReference type="EnsemblBacteria" id="EEZ39962">
        <property type="protein sequence ID" value="EEZ39962"/>
        <property type="gene ID" value="VDA_000982"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1902">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1064766at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045247">
        <property type="entry name" value="Oye-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893">
        <property type="entry name" value="PTHR22893"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxidored_FMN" evidence="1">
        <location>
            <begin position="6"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="344" mass="38899" checksum="AD69BB3933DABA29" modified="2010-01-19" version="1">MSLQMLTPIELAPNLTLKNRIVMAPMTRSMADDDLNPTIAMAEYYAKRAETGLIVTEATIVSPLGQGYPNTPGLYNESQIQHWQEVTDRVHQQGGKIFVQLWHCGRIAHSIYLNGEKPIAPSAVSFEGRVPRTDGLQYEEPRAMTDMEIERVIQEFAQAAANAKLAGFDGVEIHGANGYLIDQFLHWETNQRTDQWGGTPENMGRFLFRVIEAVQKEIDHVGLRLSPVGYLHMALNEKDREVSDYVLKKLNDYDLVYLHNGAFDDVKYDYIDGTVTQYMRRHYQGKVVGNGSYTPDIAEQVLEQKDADLVAIGRPLIANPDYVAKLKNHQPITEYNAEMLNTLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3P8</accession>
    <name>D0Z3P8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Probable Co/Zn/Cd efflux system membrane fusion protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001049</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306082.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001049"/>
    <dbReference type="EnsemblBacteria" id="EEZ40029">
        <property type="protein sequence ID" value="EEZ40029"/>
        <property type="gene ID" value="VDA_001049"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0845">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1200399at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HlyD_D23" evidence="3">
        <location>
            <begin position="71"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="144"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="368" mass="40124" checksum="8FEE4BD0BADE4699" modified="2010-01-19" version="1">MKTTTHISALTNLKVSTLAVSLALSSLVITGCGSEESTAVLPPAVKPALSEVVKAHADDELSFNGVVRSAQRADLAFRIGGRLTYIFVKEGDQVKQGQLLAKLDDRDAQTAFESAQLELKNARAEYQRGKAIFEKSQAIAKSNLDTLTTRFNLAQNRLEEAKRQLEYTQLKAPFDGIVGRKMVDNHVQVQANMPIIAIHDVQNLEVVINIPDTVMLYGLKETKAKAELSSIPGKDFALKLRTFATQADPVTQTYAVVLGFEDLKGFRVLPGMAVKVSPADPEIKLPLETTITVPLTAVVPDNQGKQFVWVVNDKNHVEKRYVKVGALSSSRIEITECLVPGERIIIAGVASLKDGMQVRPYTDDNSGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3Q4</accession>
    <name>D0Z3Q4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Probable transcriptional regulatory protein VDA_001055</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001055</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the TACO1 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001055"/>
    <dbReference type="EnsemblBacteria" id="EEZ40035">
        <property type="protein sequence ID" value="EEZ40035"/>
        <property type="gene ID" value="VDA_001055"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0217">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.980">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00693">
        <property type="entry name" value="Transcrip_reg_TACO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017856">
        <property type="entry name" value="Integrase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002876">
        <property type="entry name" value="Transcrip_reg_TACO1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026564">
        <property type="entry name" value="Transcrip_reg_TACO1-like_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029072">
        <property type="entry name" value="YebC-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12532">
        <property type="entry name" value="PTHR12532"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01709">
        <property type="entry name" value="Transcrip_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75625">
        <property type="entry name" value="SSF75625"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 4" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="229" mass="25340" checksum="BE40399635461D1B" modified="2010-01-19" version="1">MAKTQGAKIKVYSKYGKEIYVCAKNGSPDPESNLALRRLIEKAKKDQVPSHVIEKAIDKAKGGAGEDYATARYEGFGPGNCMVIVDCLTDNNNRTFMDVRQCFVKNNAKIGSPGTCGHMFEHQAVFEFKGEDEEVVLENLMMEDADVTDITCEDGVITVYAPHTEFFKVKNALAATMPEVTLDVEEISFVPQTMVELAGDDVASFEKFLDMLNDCDDVQNVYHNAEIAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3R9</accession>
    <name>D0Z3R9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator GntR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001070</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306143.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001070"/>
    <dbReference type="EnsemblBacteria" id="EEZ40050">
        <property type="protein sequence ID" value="EEZ40050"/>
        <property type="gene ID" value="VDA_001070"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1802">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1911275at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011711">
        <property type="entry name" value="GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008920">
        <property type="entry name" value="TF_FadR/GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07729">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00895">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48008">
        <property type="entry name" value="SSF48008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="4">
        <location>
            <begin position="6"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="217" mass="24855" checksum="756A2948D7FBCA4D" modified="2010-01-19" version="1">MKINKQSLEEQATEFIRNMIVSGQLAMGEKIVESTLSKDLELSRSTVRMALNSLSHEGLVVQKPYVGWHVFTLSQDDLWELYNLRVAIESQAAVMAAERATEEDKKELSRIYQDFCQFCLNDSLDIIAVCEKDFEFHRKVVEISKSNKFIKIYEQISNQLKSYIKLTHHDYDLSQSGISHNGIVDAIIAGDANRAWLESKENITTFTDLNRNNTESN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3T3</accession>
    <name>D0Z3T3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Choline-sulfatase</fullName>
            <ecNumber evidence="4">3.1.6.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001084</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="2">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <dbReference type="EC" id="3.1.6.6" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306182.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001084"/>
    <dbReference type="EnsemblBacteria" id="EEZ40064">
        <property type="protein sequence ID" value="EEZ40064"/>
        <property type="gene ID" value="VDA_001084"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3119">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1067869at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047753">
        <property type="term" value="F:choline-sulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sulfatase" evidence="3">
        <location>
            <begin position="44"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="2">
        <location>
            <position position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="517" mass="59008" checksum="D9F4C48BBCDFB65A" modified="2010-01-19" version="1">MSITRRGLLKGMAASSALVSAGLTPHAVSASEQKYANENVQKKPNLLIIFPDEFRAQALGFMKQDNSLTPNLDKFAKQSVVLRQAVSNFPLCTPFRGMLMTGQYPYRNGIQGNSHTGTPGFFGGKDFGIELKKNTVTWSDILKEQGYSMGYIGKWHLDAPETPFVPSYNNPMEGRYWNDWTAPDRRHGFDFWYSYGTYDLHLNPIYWTNDTPRDQPLHINQWSPEHEADVAINYLRNENGKYRDAEKPFTLVVSMNPPHSPYDQVPQKYLDRFKGQSSKSLNTRPNVQWDKEYLEGYGPNYFKEYMAMVNGVDEQFGRIVDELDRLNLANDTLVVFFSDHGCCMGSNGQPTKNVHYEEAMRIPMIFRWPGKLQPQQNDLLFSAPDIYPTLFGLMGMEQLIPDTVEGTNFARTLQGMKGDKTPTSQFYTFMPYGGQSYGRRGVRTDHYTLVIDRKIGKPLTVTLHDNQADPYQMKNIAADHQAIVEKLVQQELLPWLEHTGDPWRPTEVPANSAKAYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3Z6</accession>
    <name>D0Z3Z6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cell wall endopeptidase family M23/M37</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_001149</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306348.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001149"/>
    <dbReference type="MEROPS" id="M23.014"/>
    <dbReference type="EnsemblBacteria" id="EEZ40127">
        <property type="protein sequence ID" value="EEZ40127"/>
        <property type="gene ID" value="VDA_001149"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0739">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3061">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1891666at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042834">
        <property type="term" value="F:peptidoglycan binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045834">
        <property type="entry name" value="Csd3_N2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007340">
        <property type="entry name" value="Opacity-associatedA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19425">
        <property type="entry name" value="Csd3_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04225">
        <property type="entry name" value="OapA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LysM" evidence="5">
        <location>
            <begin position="78"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="446" mass="49875" checksum="151A7501C4419272" modified="2010-01-19" version="1">MSIFQTSVLQRLSNTKFLSIAGLSLVTVAVVISLNTNTTPSTATKSIELSPKTAAPQVVVDTLKPETIIKTVPLPPQFEYTIKKGDTLSGVFSKLNVSREDMQKVMESDLDSLKIDTLKPGDTLRFWLDENNHKLTKFELQQTPAQKFDYVRTPSGDFEYQETTLPGQWKSAVASGTIHGSFSVSAQKAGLDYSEVLEITNLLKDKLNFARDLRAGDTFEVVHERQFIDGKPTGQHEVRAIRIHNKGKIISAYLHTDGNYYDEDGNSLQRAFLRYPSAKQWRISSNFNPNRKHPVTGRRQPHNGVDFAAPRGTPVLATGDGVVVLTTNHPYAGRYIVIQHGTNYKTRYLHNTKILVKKGQRVHRGQEIALSGSTGRVTGPHIHYEFLIRNKPVNPMTANIPMASSVPGKEKKVFEQMVAQYNQMMKDPMSAETIQLARIKPKTKDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z430</accession>
    <name>D0Z430_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein adenylyltransferase SelO</fullName>
            <ecNumber evidence="9">2.7.7.n1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">selO</name>
        <name evidence="10" type="ORF">VDA_000286</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + L-seryl-[protein] = 3-O-(5'-adenylyl)-L-seryl-[protein] + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:58120"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:15073"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:142516"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + L-threonyl-[protein] = 3-O-(5'-adenylyl)-L-threonyl-[protein] + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:54292"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:13847"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:138113"/>
            <dbReference type="EC" id="2.7.7.n1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + L-tyrosyl-[protein] = diphosphate + O-(5'-adenylyl)-L-tyrosyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:54288"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:13846"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:83624"/>
            <dbReference type="EC" id="2.7.7.n1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the SELO family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.n1" evidence="9"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303944.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39268">
        <property type="protein sequence ID" value="EEZ39268"/>
        <property type="gene ID" value="VDA_000286"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0397">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="130048at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00692">
        <property type="entry name" value="SelO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003846">
        <property type="entry name" value="SelO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32057">
        <property type="entry name" value="PTHR32057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02696">
        <property type="entry name" value="SelO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 9" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton acceptor" evidence="9">
        <location>
            <position position="252"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="90"/>
            <end position="93"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="125"/>
            <end position="126"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="253"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="262"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ39268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="491" mass="56103" checksum="BB2D4E308B4C6E4E" modified="2010-01-19" version="1">MKRLDQLVFNNTYRQLPDVFGQAVTPIGLDNAFLVSANPEVAALLDLNPEELYTPSFVRIFSGNQQLAQFNPIAMKYTGHQFGQYNPDLGDGRGLLLGEVVTDRGQKWDLHLKGSGKTPYSRMGDGRAVLRSSIREYLASAAMSGLGIPTTHALAIIGSETPVYREQQEYGATLIRVAESHIRFGHFEYLFFTRQYPALKRLMDYVIDHHYLDLKQQENPYQALFDRICETTAEMIAAWQAVGFAHGVMNTDNMSILGLTFDYGPYAFLDDYMPNFICNHSDYSGRYAFNQQPGIGLWNLTALGYAFSAFVDKNHIESALEHYQVHLQQRYSQRIKSKLGLTLNDDSDSELGNRLFTILAEQEADYTLFFRTLSSIPYEALAEAMPKFEDIVDDPMALAPWLTTYKKRIKQELTQQTDLKRLEQMKQANPKFILRNYLAQQAIEHAERGHYEKIEALLHVLRDPFSEHPQFEHLAQQPPYWGKHLPISCSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z462</accession>
    <name>D0Z462_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted D-lactate dehydrogenase Fe-S protein FAD/FMN-containing</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_000318</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304029.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000318"/>
    <dbReference type="EnsemblBacteria" id="EEZ39300">
        <property type="protein sequence ID" value="EEZ39300"/>
        <property type="gene ID" value="VDA_000318"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0247">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0277">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0479">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1034540at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.45.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004017">
        <property type="entry name" value="Cys_rich_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004113">
        <property type="entry name" value="FAD-linked_oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016171">
        <property type="entry name" value="Vanillyl_alc_oxidase_C-sub2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02754">
        <property type="entry name" value="CCG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02913">
        <property type="entry name" value="FAD-oxidase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12838">
        <property type="entry name" value="Fer4_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="SSF55103"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="6">
        <location>
            <begin position="38"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="534"/>
            <end position="565"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="941" mass="103975" checksum="C33CD1C5882E215F" modified="2010-01-19" version="1">MDTSYQELLEILNQHIESTRIITDPTLTFAYGTDASFYRLIPKIVLQLDSLDEVIFTVKQCYRLHIPVTFRAAGTSLSGQAISDSVLITLTTNWRHHKILNNGEQIWLQPGIIGADANRYLLPYGRKIGPDPASINTCKIGGIAANNASGMCCGTAQNSYQTLAGMTIVFVDGTLLNTLDKHSVEAFKQSHNDLLLELKQLAASCKENRSLSDKIRHKYRLKNTTGYSINSLIDFDDPIEILQHLMIGSEGTLGFIADIIYNTVIDHQFKASGLYVFDNIESTCLAVSELAKTSVAAVELLDNRSLASVADQPGMPEFIAKLQADGNTEAAALLIEVHGLHREDLNEQIAVLTQIIASFKTIAQIEFSQDKALCDQLWAIRKGVFPAVGAVREVGTTAIIEDVAFPIEKLAPAVRQLQQLFIQFGYHEAIIYGHALAGNLHFVFNQAFDSEAEIQRYADFMEAVAQLVAVEYQGSLKAEHGTGRNMAPYIELEWGSDGLQLMQSIKRIFDTHGVLNPGVIINSDHQSHIRHLKQMPAADELIDRCIECGFCEPACPSRNLSLTPRQRNVVYREICRLRKTNESPERLHQMEQAYQYLGLDTCAATGLCADRCPVGINTGDLVRKLRQNHSEKAKSIAKWTGEHFAAVTRGAKLGLAAADGLHKVLGTKNMSSMMQRVRTLSGQRVPLWTSHMPMPAHKMLPPTIFSIEKEKVVYFPSCSTRNMGTERGASDERSLMDITVSLLEKAGFQVILPDELNNLCCGMPYKSKGYVDTAKDKAYQLEQALLHVSQQGTLPILMDTSPCASLSKDVMSSELTIYEPFKFVADFVLPRLTITPQKEPVMLHITCTSRRKGLAGVMEQVTKQCAETVIIPEDVTCCGFAGDKGFTTPELNASALSSLKVQVPVNCSEGYSNSRTCEIGLSEHSGIEYRSILYLIDKVSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4B2</accession>
    <name>D0Z4B2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative outer membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000368</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304171.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000368"/>
    <dbReference type="EnsemblBacteria" id="EEZ39350">
        <property type="protein sequence ID" value="EEZ39350"/>
        <property type="gene ID" value="VDA_000368"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1881">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1150223at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00865">
        <property type="entry name" value="PEBP_bact_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008914">
        <property type="entry name" value="PEBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036610">
        <property type="entry name" value="PEBP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005247">
        <property type="entry name" value="YbhB_YbcL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30289">
        <property type="entry name" value="PTHR30289"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01161">
        <property type="entry name" value="PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49777">
        <property type="entry name" value="SSF49777"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00481">
        <property type="entry name" value="TIGR00481"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018840" evidence="1">
        <location>
            <begin position="22"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="184" mass="19321" checksum="6FF22149D188BB92" modified="2010-01-19" version="1">MKLKHLAAGILLAVPAFMTQAMTLKSADVTNDKTLSSAQVFNQWGCTGSNESPQLTWSDVPAGTKSFAVTMYDPDAPTGSGWWHWVAINIPADVHSLKEGAGNVDGKNLPAGASMVTNDFGFKGFGGACPPPKAKPHNYTITVYALNTAKIDLPANASPALAGYNILGHVIGKAELIAPTNTRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4E4</accession>
    <name>D0Z4E4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 13">Penicillin-binding protein 1B</fullName>
            <shortName evidence="13">PBP-1b</shortName>
            <shortName evidence="13">PBP1b</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12 13">Murein polymerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">VDA_000400</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 13">Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>[GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-di-trans,octa-cis-undecaprenyl diphosphate + beta-D-GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate = [GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-di-trans-octa-cis-undecaprenyl diphosphate + di-trans,octa-cis-undecaprenyl diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23708"/>
            <dbReference type="Rhea" id="RHEA-COMP:9602"/>
            <dbReference type="Rhea" id="RHEA-COMP:9603"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58405"/>
            <dbReference type="ChEBI" id="CHEBI:60033"/>
            <dbReference type="ChEBI" id="CHEBI:78435"/>
            <dbReference type="EC" id="2.4.1.129"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 13">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">In the C-terminal section; belongs to the transpeptidase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">In the N-terminal section; belongs to the glycosyltransferase 51 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000400"/>
    <dbReference type="EnsemblBacteria" id="EEZ39382">
        <property type="protein sequence ID" value="EEZ39382"/>
        <property type="gene ID" value="VDA_000400"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0744">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009274">
        <property type="term" value="C:peptidoglycan-based cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008658">
        <property type="term" value="F:penicillin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008955">
        <property type="term" value="F:peptidoglycan glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009002">
        <property type="term" value="F:serine-type D-Ala-D-Ala carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3810.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001264">
        <property type="entry name" value="Glyco_trans_51"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011813">
        <property type="entry name" value="PBP_1b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036950">
        <property type="entry name" value="PBP_transglycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001460">
        <property type="entry name" value="PCN-bd_Tpept"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028166">
        <property type="entry name" value="UB2H"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00912">
        <property type="entry name" value="Transgly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00905">
        <property type="entry name" value="Transpeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14814">
        <property type="entry name" value="UB2H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002799">
        <property type="entry name" value="PBP_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02071">
        <property type="entry name" value="PBP_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="13" id="KW-0133">Cell shape</keyword>
    <keyword evidence="13" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="8 13 18" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="13" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="7" id="KW-0645">Protease</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13 18" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="UB2H" evidence="17">
        <location>
            <begin position="9"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="Transgly" evidence="16">
        <location>
            <begin position="105"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="Transpeptidase" evidence="15">
        <location>
            <begin position="369"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for transglycosylase activity" evidence="14">
        <location>
            <position position="129"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate; for transpeptidase activity" evidence="14">
        <location>
            <position position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR002799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR002799-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF14814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EEZ39382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="722" mass="80610" checksum="D225A6074FF91F22" modified="2010-01-19" version="1">MVYARELTLQPGSPISYKNLLNELRVLHYTKVKKPDESGEYSANGWRIEFVRRPFQFKEGAEGARDVAVTFDGNSIKQITDLDKNQELGFLRMDPKMLGMLESRTPEQRIYVPADKMPKELVNGLIATEDRHFYEHDGISLVGIARAFIANIKAGHTVQGGSTLTQQLAKNMFLSSERSLWRKAKEAYMAIIIDARYGKQEVLDAYMNQVYLAQNGNHGIHGFALASRYYFGRPLSELRIDQMALMVGLVKGPSYYNPWRYPERAKERRNVVLKLMADNNVITQEQYQDAIKLPLDIQAKGELSKRQPAYFGQIRAELEEKVGDAFKSGEGLRLFTSLDPQSQDAADQAVKKMIPIIEKQRAGKDLETAMVIADRKTGEIRAMIGSSNPGYAGYNRAIDAQRQIGSVVKPAIYLTALAQPEKYSLATTLEDKPLSIKLPNGDVWKPRNYSRTFSGQVPLFLALAKSMNVPTVNLGMALGVENVIKTMVTLGVDANDIPDVPAILLGAVALPPLQVAQMYQTITNEGAKAPLTALNAVVDEKGDVLYQNWPKAAQVVPPQAAWLTTYDMQQVVKQGTARSLGRMYPNMHLAGKTGTTDQGKDSWFVGADGREVVAVWMGRDDNKSANLTGSTGALRLYEDYIKRRGPEPLELRLPANITGFNYDVMPDGTYQQSCTGTTRLPVWDPNNDLKMDCSVPVQQQVKEHVQEAQQQVEGFFNRLFNW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-06-02" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4H7</accession>
    <name>D0Z4H7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000435</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000435"/>
    <dbReference type="EnsemblBacteria" id="EEZ39415">
        <property type="protein sequence ID" value="EEZ39415"/>
        <property type="gene ID" value="VDA_000435"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1470">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001434">
        <property type="entry name" value="DUF11"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01451">
        <property type="entry name" value="B_ant_repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="257"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="274"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="934" mass="95084" checksum="1DF417F4C28F1C9D" modified="2010-01-19" version="1">MAGGEQMNLIVAAAVPTTAVPGDTLGVTLEAEANNGTGSAVDGSVTDIGDNNDSADDTNASLITVTNDAVINMTKSATHLENIGTESSLGIDLDGDGATDRALSLIRYTVTVSNTGNTDAKDVVIFDGIPDGTVFVTGSTGAAYDATSSGLLTVNGDTPIAYAANLVDEASHGVDLDQDSTNDTAESQIDGGLDLNGNGVTTDTTVPGVYAVDDQLASNTTVSMTFYVAYSPETMQGDTEIGNVAYSCSDLNGDGDYVDAGECNDPDPTTAGPDPSNPTTTTTTTTTGVGIIDTGTETGTSGGGDSDGTDNNTQTVDSAAAGSDVFFYNKIINNGNTVDSFDLTTVNTSFPAGTTFEYWNADGSAQLVDTNGNVTPDTGPVNPSTCTDAATTIDGITVNCNETLFRVVAKLPSDAADSTTPFDAVTTATSYNDATQSDTKTERLDNITGPTVDIANTPITAIDPAVDVDPVDTGDGFTSADVATVFNDEPLGSTVTAPIYIANEGGSSDSFLLGAEGSYNGASWETALPAGWTVVFKHNGIDTNADGTVDIAATGAVITSTPTIPAGAVLWVTAEITIPSDPTQALADSDQASAIDANTDGDLDYIISLTVQSTASGAIDRKVEAFDVATSASIDITPTSLSNQIEPGGSVTYEHTLGNTGNTTETVDLSSGNNTTGFNNTISIDTNGDGTPDTEVGNLCDAPVTSPITVQQADGSTADVEVTCDATDGSDTVPSLTLEPGETIPMEVTVFAPTDATSGTNNITTITAVSTTDPTVTAEGQDNSEVIKGQVRLYKYADLDTDCDGAADTDKTFLKQHTTTVEPGQCIVWKLIAVNEGTSDALNTVITDQLTEYTQFEAGGSLVSCRNTTDAGTVVALADATYPLQSDDLGPLCLPDGTTGADVTGAVSGNTVTFTVGTLVPGDKAVGHFVVKVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4I4</accession>
    <name>D0Z4I4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GGDEF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000442</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304378.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000442"/>
    <dbReference type="EnsemblBacteria" id="EEZ39422">
        <property type="protein sequence ID" value="EEZ39422"/>
        <property type="gene ID" value="VDA_000442"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3706">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033444">
        <property type="entry name" value="MASE5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17178">
        <property type="entry name" value="MASE5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="2">
        <location>
            <begin position="234"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="367" mass="42195" checksum="91201784D831D718" modified="2010-01-19" version="1">MTTLPLRNSLERAVYKNLQQGIRWCSAISLIVMAMMLFTLKTMSIDKELFDWEPSSYQYSFQLVIYVAGLFSFSTTPHRYWRYECDTYAILFGLSWSIAIYHIAIIYQSFLSASIFANLLMMAALLALYSRTQTLYLAVTPIFLISSWSYFVRDDYAILIALQETTATILIIETGRRILSRWFTRSVERDVENKRLLSELTQLASRDQLTNLYNRRFFEYELDKQTVQAKRYNIPFSVILIDIDYFKRYNDALGHLQGDECLKIVAKVLNASLLRGADSVSRYGGEEFVVILPNTDIDGAILVAERIQSNMAKMVIPHPDSEISNVVTLSQGIAAWKNHRGPTQLIKEADNHLYQAKELGRAQYKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4I6</accession>
    <name>D0Z4I6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hypothetical cytosolic protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000444</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304383.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000444"/>
    <dbReference type="EnsemblBacteria" id="EEZ39424">
        <property type="protein sequence ID" value="EEZ39424"/>
        <property type="gene ID" value="VDA_000444"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3420">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4932">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="149660at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001434">
        <property type="entry name" value="DUF11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045474">
        <property type="entry name" value="GEVED"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20009">
        <property type="entry name" value="GEVED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01451">
        <property type="entry name" value="B_ant_repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GEVED" evidence="2">
        <location>
            <begin position="397"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="340"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="864" mass="91683" checksum="B7B9905C0373100F" modified="2010-01-19" version="1">MSYRSLPYILYTGLVFLPLSVPFPSHSAEGVGLVFQSTLLDIGGNGGGEFGERLCPSGLLMTGFDFYNSNTGGNLDGRALRGQCSQATVSGGTATLTRAGETPWGGPVSGTLYSGSCPANQAVVGVDAQTTTWPVMGWFRLYCAPVAFNTTTNKLEIGAAPGGPSTGRIGPNFGYGGTYYNRVVAPAGQALGGFNGRSGAALDKVRFRAYSFVQASITLNASVISGSALPTDFTLIATDSNSIPAVFSHGDTKAMTPSNYTFTWTGPADYELVSFSCADPLSVTNGNSYNCTYTFRSTKVDYGDAPISYGGLTTASHGFGNSAIYLGSVEPDFEDDRFTNGIDNSLNATDDDSEGTTPNDEEALVPGFIVLNSSANATLYSLAIPCNDFDGSDLGATVYGWIDTDRNNSFDNDEFASASCNDTSATLNGNAILSWSNLDISTVSGMSYIRLRITTSSLSASDQLTNAADGEIEDHQFELINQITLRGTVFEDNSGNGSGIAHNGIIDGNEQGIGNATVEVVLNDTGVTGYNLGDVITSRKTSGNGRYTFILPVEFSGKNLIIRVRPVATLIDISESDLSAIPQASSTSVTDSEININAQAGDDIDGLNFGKVREPIMEPNHYVEIIPNQTITLNHQFRSYTDGNVTFSLVDTETIPAQPQWSAILYQDLNCDQLINSNEVRITAPLTVTESSQICLISKIFSPANIFNQSKFSYKIQADVNFDDPATTNHNISRRLYNTDTIKAIYGGSGQLELNKTVQNLTQNGTIATANTAKPGDILEYRIIFTNVGNADISDPQIFDSIPKHTRAQTAISCGGNVPTSLSCNVSTPDGTNNTGYLGSIYWSFTGALASGASGTVSYRVVID</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4J3</accession>
    <name>D0Z4J3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Membrane protein suppressor for copper-sensitivity ScsB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_000451</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000451"/>
    <dbReference type="EnsemblBacteria" id="EEZ39431">
        <property type="protein sequence ID" value="EEZ39431"/>
        <property type="gene ID" value="VDA_000451"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4232">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4233">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02953">
        <property type="entry name" value="DsbDgamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003834">
        <property type="entry name" value="Cyt_c_assmbl_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035671">
        <property type="entry name" value="DsbD_gamma"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028250">
        <property type="entry name" value="DsbDN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11412">
        <property type="entry name" value="DsbC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02683">
        <property type="entry name" value="DsbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0201">Cytochrome c-type biogenesis</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003020000" evidence="3">
        <location>
            <begin position="30"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="303"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="346"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="384"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="433"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="461"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="494"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="521"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="551"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="domain" description="DsbC" evidence="5">
        <location>
            <begin position="58"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="DsbD" evidence="4">
        <location>
            <begin position="307"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF11412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ39431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="700" mass="76506" checksum="700C3E272323C1CA" modified="2010-01-19" version="1">MKTLRFTKPYFGLVIMTIWALMMSLSVHASTLTTGWVHNPQHPPVAVRLMLTGEKNEANKTVEGLLEVKLDKDWKTYWRSPGEGGTAPSINWELSSNLNSVDWHWPLPKRYEFLGVETLGYKHDVIFPMTFHLDDMNKPVFLSGKLTMSSCTSICVLTDYELSLDFNPEKLVPSVDAMVLYNKGNSLVPKPSTAVELTQVSYDEAKKIVSIVATNKAGWTNPDVFVDGQSKPVKQTSFLTPKIDVSGEQLIAQVPVSSWFGTPKLVGEPLSVTITDKDIAVELSKTADNKPVIALQNDSLLKVIGLALLGGLILNIMPCVLPVLGMKLSSVISAKGLERRQIRAQFIASALGILVSFWLLAGFLALLKVSGQALGWGVQFQSPWFIGAMMIITGLFAANMLGLFEIRLSSNTNTWLATRGGNSYGGHFVQGMFATLLATPCSAPFLGTAVAFALGANYLNLFAIFTALAVGMAAPWLLIALFPQLANALPKPGMWMNTVKTIFGLMMLVTSLWLLSLMANFFSLKIVIVIGVIALALLLSQLWRIKGKRATLLTVGFLIIVTAIGLIIGSLTADKWAKPLPQDHHWTPLNVEQIKQDVAQGKTVFVDVTADWCITCKANKVGVILQEPVYSALDQENIVLMRGDWTKPSDYVTNFLQSHGRFGVPFNIVYGPAAPNGIELPVILTSEQVLDALKQASSKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4M4</accession>
    <name>D0Z4M4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Biotin sulfoxide reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_000482</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
            <dbReference type="ChEBI" id="CHEBI:60539"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304487.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000482"/>
    <dbReference type="EnsemblBacteria" id="EEZ39462">
        <property type="protein sequence ID" value="EEZ39462"/>
        <property type="gene ID" value="VDA_000482"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0243">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="88184at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043546">
        <property type="term" value="F:molybdopterin cofactor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041460">
        <property type="entry name" value="Molybdopterin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006657">
        <property type="entry name" value="MoPterin_dinucl-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006656">
        <property type="entry name" value="Mopterin_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00384">
        <property type="entry name" value="Molybdopterin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18364">
        <property type="entry name" value="Molybdopterin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01568">
        <property type="entry name" value="Molydop_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="SSF50692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0574">Periplasm</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Molybdopterin_N" evidence="9">
        <location>
            <begin position="40"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="Molybdopterin" evidence="7">
        <location>
            <begin position="86"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="domain" description="Molydop_binding" evidence="8">
        <location>
            <begin position="655"/>
            <end position="771"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF18364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ39462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="888" mass="98585" checksum="6725C842B30BA124" modified="2010-01-19" version="1">MDVSRRSFLKSAIATAIAANGLTLFPLDYAFADDTVLIPSASHWGPFYAVVKKGVLVGIQPRKEIDPLPTEMLLKGLLSRTYNKTRIQYPMVRKSYLENLGGNTKPELRGKEPFVRVSWETALQLTANAILHTIETKGNQGIFDSSYDGWSNTGLLRPPVVQGRFFNLIGGCSTTIGDYSAGASTVILPHIVGDMEVYSPQTAWPVIEKNTEVFVLVGADPWKTNRVEFRVADHQMQSHWLEWKKKGIKFISINPQRTTTDENLGSEWISITPGTDTALFNAMAYHLHDKNLVDEAYVNKYTVGYPQYVEYLLGTKDGIPKTPEWAAMITGISAEQIKQLTELFKNKKTQIAAGWALQRADHGEMVHWAIINFAAMAGKIGKPGEGFGFSWHYGNGGMPQSGAALPVTIGQGHNAVSAGCPVVLQAEMLKHPGKAFTYNGQTLTFPDVTMIYNSGNNLFSHQQNLNALLDAMNKKVETYVCQDTWWCASARYADIVLPATTALERVDITSGGTYSNDKVYAMQQVIEPYGESLDDFEIFRRLAKLFGVEQQYTTGKDMMGLIKEAYANSTAGKLKPFDQFWKDGVTHLPVPKSADYWQRHGAFYDDPKKNPLHTPSGKIELYSQAIADMNIWDCPPVPTFMQPFEYLGNADKGQLHILSPHPWMRLHSQMANADTNSYECVDGRQFLLINEEDAKAQGIADGDLVELYNGRGALLCGARLAKDLHRGVACLHEGAWMQLDKLGRCNSGQINVITSDRSCGGLSQGTSANTCLAYYKKCTNPCSPNQAYEPPHIVAESDCQMMMSLATLNIPERINKFMHSSVSNKPQQSIGEKIFYERCTMCHAAPDPASHTKGQWDGITQSMFPRAGLNDQEKKEVLDFLYKHAAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4T6</accession>
    <name>D0Z4T6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000169</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306498.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39153">
        <property type="protein sequence ID" value="EEZ39153"/>
        <property type="gene ID" value="VDA_000169"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031PT5">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="270" mass="31541" checksum="8265308CDE497725" modified="2010-01-19" version="1">MSTKTVSIEQKAIAQRINELGSSKNELRKAQFPYCTRRTLLAFAKFIDNPHAYENQLHDLLHCQTRVGGLQKRQRMNCVKVMTVLMSKMDVENYQIGFAKSEEMETITHAWFMARYEQYWGESISLKRYYHTIHLLKMADYLMVDAVFVYDEEVPPALDDNGQIKEEDAPRIYSKAAYKTITAKFMGIFGLEHDEGVVKSKLQAVKNRVAKRLSNIWWVYAPYSYSYTWTKRQLAKVTKRDRVTGKERDRYPQGKVIEPDILGGNYLTEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4U5</accession>
    <name>D0Z4U5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_000178</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the transposase 7 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306524.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000178"/>
    <dbReference type="EnsemblBacteria" id="EEZ39162">
        <property type="protein sequence ID" value="EEZ39162"/>
        <property type="gene ID" value="VDA_000178"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4644">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="45599at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025296">
        <property type="entry name" value="DUF4158"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002513">
        <property type="entry name" value="Tn3_Tnp_DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01526">
        <property type="entry name" value="DDE_Tnp_Tn3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13700">
        <property type="entry name" value="DUF4158"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0814">Transposable element</keyword>
    <keyword evidence="3" id="KW-0815">Transposition</keyword>
    <feature type="domain" description="DUF4158" evidence="7">
        <location>
            <begin position="17"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="DDE_Tnp_Tn3" evidence="6">
        <location>
            <begin position="602"/>
            <end position="994"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ39162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="1015" mass="118057" checksum="C8F186F1E04BF436" modified="2010-01-19" version="1">MTTRGKVTGKSERLAVLNNAEQEALYGLPDFDDTQRLEYLALDESELAQACSRPGLHAQIYCILQIAYFKAKHLFFRFGWDDVKDDCNFVLNRYFHGESLPDLSPTKHERYAQREKICVLYGYRPWSSALSSQLEYQAVNIVRRDVTPGFVATELIIWLNEHKIIRPGYTTLQELVSRILSDERQRLGRILAERLDDTTITGLDKLIERDDTLSRLAVLRQDARDFGWRQMVHEREKRTILEPLHRKACDVLPELNISQQNLLYYASLANFYTVYDLRKLKPGQTRLYLLCYAWIRYRQFSDNLVDAMFFHMKQLEDESRRVAKQLMADVQEKHRRETSKIGRLLSLYVDDSVPDPTTFGEVRRRAWKIMPRETLKTTAQRMSVKPVSRLALQWQVVDCMTALIRRHLRPLYLSLDLASVVQDSPWAEALSWLKMVFSKKMTLSQRPLAECPPETLPERLRPYLLVFDEDGEPTGLNAGRYEFWLYRQIRKRFQSGEFHLNDSLRHRHLSDELVSAEEQAAVLADMKIPFLQKPIKTQLKALESELHRQWKAFNRELKQGKLKHLEYDKETQKLTWHKSVVSRHKAQKKRFYEQLPFCDITDIFRFVNEQCRFLPAMKPLQPRYAKKYADADSLMAVIVAQAMNHGHNVMARTSDIPLHVLETTYEQYLRLASLLTANNCITDAIEALPVFPLYSFDPETLYGAVDGQKFGVERPTVKARHSRKYFGRGKGMVAYTLLCNHIPINGYLIGTNEYEGHHVFDIWYRNTSEVKPTAITGDMHSINKANFAILHWFGLRFEPHFTDLNKQLKELYCTREPSAYKKCLIQPVGQINQDLIIREKNNLDRIVATLGLKEMTQGTLMRKLCTYTTTNPTRQAIFEYDRLLRSIYTLKYLRDPQLERNIRRSQNRIESYHQLRAAVSKVGGKKELSGKNDLETEISNQCGRLISNAIVYYNSAILSRLLERLEAEGNAKGIEALTRISPVAWQHILLNGHYTFHSSNEIMDLDALVAGLKLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4V7</accession>
    <name>D0Z4V7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Type III secretion host injection and negative regulator protein (YopD)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000190</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306559.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000190"/>
    <dbReference type="EnsemblBacteria" id="EEZ39174">
        <property type="protein sequence ID" value="EEZ39174"/>
        <property type="gene ID" value="VDA_000190"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5030UVY">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1116626at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008898">
        <property type="entry name" value="YopD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05844">
        <property type="entry name" value="YopD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="153"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="130"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="286" mass="30359" checksum="21461F605931CDED" modified="2010-01-19" version="1">MLDKIGNTGRTDLYGLGELDKSTKAEKAPETKTEAAAIRGNGEATVSGPKHYQLDGPKAPAIGDQARVVEKLMSALAPTVNLLMQTTEKALNGEQVIKSPSEVVSQSLSLLTLLYQVSKLSREQQVLQREIAVEANVASLKSQAEELNNSAKAMIAMAVISGVLAGITAIVGVVGSMKAGKYIKQEAAGSAIAANKFQKQMATNNAVNTVIQAIGQMANSAANVEQTKAQARSKEDEILATHAQASKQKADENVGFQEGLLKELRELFRSISDSQNQAWRASIPTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4W3</accession>
    <name>D0Z4W3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Type 3 secretion system ATPase</fullName>
            <ecNumber evidence="7">7.4.2.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">VDA_000196</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.</text>
    </comment>
    <dbReference type="EC" id="7.4.2.8" evidence="7"/>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000196"/>
    <dbReference type="EnsemblBacteria" id="EEZ39180">
        <property type="protein sequence ID" value="EEZ39180"/>
        <property type="gene ID" value="VDA_000196"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1157">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030257">
        <property type="term" value="C:type III protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030254">
        <property type="term" value="P:protein secretion by the type III secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005714">
        <property type="entry name" value="ATPase_T3SS_FliI/YscN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013380">
        <property type="entry name" value="ATPase_T3SS_SCTN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040627">
        <property type="entry name" value="T3SS_ATPase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18269">
        <property type="entry name" value="T3SS_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01026">
        <property type="entry name" value="fliI_yscN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02546">
        <property type="entry name" value="III_secr_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <keyword evidence="5" id="KW-0843">Virulence</keyword>
    <feature type="domain" description="AAA" evidence="10">
        <location>
            <begin position="142"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="402"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ39180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="421" mass="45678" checksum="36AF248E7AC32242" modified="2010-01-19" version="1">MIQIRGRVTQVTGTIIKAVVPGVRVGELCELRNPDQTLSLLAEVVGFQQHHALLTPLGNMFGISSNTEVSPLGKMHEVGVGDHLLGKILDGLGRPFDGSQSTEPSAWYPVYRDAPPPMQRKLIEKPISMGVRSIDGLLTCGEGQRMGIFAAAGGGKSTLLAKLIRSADVDVTVLALIGERGREVREFIEHDLGEKGMARSVLVVATSDRPAMERAKAAFVATSIAEYFRDQGKRVLLLMDSVTRFARAQREIGLAAGEPPTRRGYPPSVFAALPKLMERAGQSDKGSITALYTVLVEGDDMTEPVADETRSILDGHIILSRKLAAMNHYPAIDVLRSASRVMNQIVDKTHQASAAHMREMLAKYEEVELLIKIGEYQHGADSRADMAIAQGDDIRAFLRQGTHEPSELEETVTQLSGLAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z538</accession>
    <name>D0Z538_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Conjugative transfer protein TrbC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000273</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306791.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000273"/>
    <dbReference type="EnsemblBacteria" id="EEZ39255">
        <property type="protein sequence ID" value="EEZ39255"/>
        <property type="gene ID" value="VDA_000273"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5030AFU">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1761021at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019106">
        <property type="entry name" value="T4SS_TrbC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014113">
        <property type="entry name" value="T4SS_TrbC_subgr"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09673">
        <property type="entry name" value="TrbC_Ftype"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02742">
        <property type="entry name" value="TrbC_Ftype"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018863" evidence="1">
        <location>
            <begin position="21"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="216" mass="23638" checksum="24D1F7F82B6188E5" modified="2010-01-19" version="1">MKPAKLALILLCSVGLPVQAWTEQETHELQRQKEAQAASFFTPDTNTLNIESLLKAKQYKKMAQALNDEANNRIISTQNPNAAPPSVLIFASLNMPSASLKQLLYQANQYRLPVVIRGVLPGGFTQTVNMVQGLVAPNHAKKPLGGVSINPIWFKQFNIKQVSAFVVMKEGACQGKPPCDPDNYDVVYGNVSVFDALTTLGQRGQYADIANRVIAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5G9</accession>
    <name>D0Z5G9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Conjugative transfer protein TrbJ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000076</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000006">
        <property type="protein sequence ID" value="EEZ39021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005307163.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000006.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000076"/>
    <dbReference type="EnsemblBacteria" id="EEZ39021">
        <property type="protein sequence ID" value="EEZ39021"/>
        <property type="gene ID" value="VDA_000076"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5314">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1073216at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014147">
        <property type="entry name" value="T4SS_TrbJ"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02780">
        <property type="entry name" value="TrbJ_Ti"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003020055" evidence="2">
        <location>
            <begin position="26"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="47"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="258" mass="29072" checksum="E4E016BA33098544" modified="2010-01-19" version="1">MRKNTKLTYLSMLLSGLLLSSSAHSIAVVCVNCATNTQALQANIAQAKDYIESVQRTLNSIKQLENQIKNMAKIRDMEWGDIDSQLRDLSNIASQGQALTLSVESLNREWDNKFQGYDVYRHQANSPENTTRQYKQWSNTLRDTSRNALKFANQVAQSRKDDNDAIREIQSHVNNAQGAVQVAQASNELQVQALGSLQKVQALMETDIRMTATEISTANDKLDAQKAADDQLHSRKLSEELNYRNGVNWFDRLGKKPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5H0</accession>
    <name>D0Z5H0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Conjugative transfer protein TrbB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000077</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GSP E family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000006">
        <property type="protein sequence ID" value="EEZ39022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005307167.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000006.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000077"/>
    <dbReference type="EnsemblBacteria" id="EEZ39022">
        <property type="protein sequence ID" value="EEZ39022"/>
        <property type="gene ID" value="VDA_000077"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4962">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="473670at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014149">
        <property type="entry name" value="Conjug-transfer_TrbB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001482">
        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00437">
        <property type="entry name" value="T2SSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02782">
        <property type="entry name" value="TrbB_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T2SP_E" evidence="2">
        <location>
            <begin position="26"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="313" mass="35154" checksum="6D2942A00F1BBBC8" modified="2010-01-19" version="1">MQNNKRIAKSINYHIDRCGLTPFLSNDSVTEIMLNPDGNCWIDEFGKPYYISHKIEPILAQNLINAVADSVQLIVDRDHPILECELYSDGSRFEGVVPPVVPNVSFTIRKKATRVFTLEDYLDSKIITQEQFDYICQAISERKNILVVGGTGSGKTTLVNAILAKMAELFPHERHLILEDTNELQPSAENSVVFRTHSRANVTMRELLRATLRYNPNRIIIGEVRGGEALELLKAWNTGHEGGIATVHANSAALGLERIEQCIEEVTPIANKRMIASTVHTLIYIEKSHEGRKIKEICEVVGYDGNQYLTNII</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5I6</accession>
    <name>D0Z5I6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Site-specific DNA-methyltransferase (adenine-specific)</fullName>
            <ecNumber evidence="2">2.1.1.72</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_000004</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:15197"/>
            <dbReference type="Rhea" id="RHEA-COMP:12418"/>
            <dbReference type="Rhea" id="RHEA-COMP:12419"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90615"/>
            <dbReference type="ChEBI" id="CHEBI:90616"/>
            <dbReference type="EC" id="2.1.1.72"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.1.1.72" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000007">
        <property type="protein sequence ID" value="EEZ38997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000004"/>
    <dbReference type="EnsemblBacteria" id="EEZ38997">
        <property type="protein sequence ID" value="EEZ38997"/>
        <property type="gene ID" value="VDA_000004"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0827">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1178320at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011639">
        <property type="entry name" value="RM_methylase_Eco57I-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07669">
        <property type="entry name" value="Eco57I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0680">Restriction system</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Eco57I" evidence="4">
        <location>
            <begin position="145"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ38997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="504" mass="56278" checksum="80525EFA17E545F0" modified="2010-01-19" version="1">MTALAQNIPLNLNDIADINRVTVNGKLDESLRGKLGQFMSSSAVSKILADMFENINGEHRILDAGAGVASLTAAFVERVQDHATSIDSTCYELSSIMNYYLIDTLQHCSNSCNYNDVQWNQTVIEEDFIAHSVALLQRDDFTPRFNKAILNPPYLKISAKGSERADLRKINFETGNLYSAFVGLAIKLIEDGGELVAITPRSFCNGPYFNSFRKLLLDNCSINKIHVFNSRKSAFKADKVLQENVIYHLTKGEAQRDIVIVTSSSCADDPNPSVYEVPFDKIVSNNNPDRFIHIITDEEELNIATKAGGLPCSLDNLGIQASTGKVVDFRTRENLSQNYIDGSVPLIFPQHLQKCSIEWPINNGKKPNALLNNKNTASLMVKNGTYVLTRRLTAKEEKRRVVASIYTANIADVDVVGFDNKTNYFHALGEPLDDALAKGLWVFLNSTLVDKYFRQMNGNTQVNATDLRTLRYPTRSQLVLMGSMVDFEDFKQINIDSIVESVLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5J2</accession>
    <name>D0Z5J2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000007">
        <property type="protein sequence ID" value="EEZ39003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005307248.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000007.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000010"/>
    <dbReference type="EnsemblBacteria" id="EEZ39003">
        <property type="protein sequence ID" value="EEZ39003"/>
        <property type="gene ID" value="VDA_000010"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502Z9ZM">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1258110at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05400">
        <property type="entry name" value="NT_2-5OAS_ClassI-CCAase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006116">
        <property type="entry name" value="NT_2-5OAS_ClassI-CCAase"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="341" mass="38628" checksum="A58AD9C679E7E130" modified="2010-01-19" version="1">MSTQSKFIKFHDKIKLSREDCEYKDAREKDDSILKAIKTSLKDEGYPVIDNFLQGSMSTSTGVKNRGEDFDIDRAVVIAFDDSPDDPVKVKKIVLKVLEDRGFKNAKIKKPCVTADYISKNLHIDIPIYRECNGNYELAIGKKNSGDDSKEWSASDPKGLKEWINDASLYTGSANKKLEQYKRIVRYLKRWRDNKFSTAVAKKVFSISLTVMAKEQFKPSLDDNNKANDLVALRDTVNDMLHADYFSYQGNEQYRVRVTLPKSPWRDIFYGSSLNTGTQFYNKLTTLKNKLDKAIEETDLTKQCKILNEVFGDDFEVPSSSSTIRKATYSTAGASGTSQGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVH6</accession>
    <name>D0YVH6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Rhomboid domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_001556</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001556"/>
    <dbReference type="EnsemblBacteria" id="EEZ40530">
        <property type="protein sequence ID" value="EEZ40530"/>
        <property type="gene ID" value="VDA_001556"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0705">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2053476at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023826">
        <property type="entry name" value="Rhom-like_SP_proteobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="SSF144091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03902">
        <property type="entry name" value="rhom_GG_sort"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="51"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="76"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="157"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="Rhomboid" evidence="6">
        <location>
            <begin position="35"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="185" mass="20365" checksum="2F55966E6874DFB7" modified="2010-01-19" version="1">MSIRTYLLLAIIIGVIAQFPSLSPYLNWDRNAILDGEVWRIVTGNITHTNWPHLIMNSIGFIIITFIFRRHFQPKIYTLVIFTLSMAIGIGLFATSILWYAGFSGVLHGLFAWGAVKDIQSKNKEGYLLLLALAAKVGWDCFSGGSTESASLIGAHVAVQAHLIGAITGTFIGLSSYIQKNENSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVI0</accession>
    <name>D0YVI0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aspartate/tyrosine/aromatic aminotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001560</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298278.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001560"/>
    <dbReference type="EnsemblBacteria" id="EEZ40534">
        <property type="protein sequence ID" value="EEZ40534"/>
        <property type="gene ID" value="VDA_001560"/>
    </dbReference>
    <dbReference type="GeneID" id="57342382"/>
    <dbReference type="eggNOG" id="COG0436">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="554560at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="1">
        <location>
            <begin position="36"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="404" mass="45460" checksum="74FFEED4ADC04092" modified="2010-01-19" version="1">MQNFGMSSKLNNVCYDIRGPVLKHAKRMEEEGQKIIKLNIGNPAPFGFDAPDEILVDVIRNLPTSQGYCDSKGIYPARKAIVQHYQKRGMLDLDVEDVYIGNGVSELIVMAMQALLDHQDEILVPSPDYPLWTAAVSLSGGTPVHYICDEESDWYPDLDDIKKKITPQTKGIVLINPNNPTGAVYSRDFLLEVVEIARQHNLIIFADEIYDKILYDGAQHTSIAPLAEDVFCITFNGLSKSYRVCGFRAGWMVLSGPRQKAKGYIEGLDMLASMRLCANVPMQHAIQTALGGYQSINELILPGGRLLEQRNKAYELLTQIPGVSCVKPKGALYMFPKLDQKKFNIVDDQRMALDFLQQEKVLVVHGTGFNWKQPDHFRIVTLPRIDDLEIAIGRLERFLSGYRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVM0</accession>
    <name>D0YVM0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Selenide, water dikinase</fullName>
            <ecNumber evidence="5">2.7.9.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Selenium donor protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Selenophosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">selD</name>
        <name evidence="8" type="ORF">VDA_001589</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Synthesizes selenophosphate from selenide and ATP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + H2O + hydrogenselenide = AMP + 2 H(+) + phosphate + selenophosphate</text>
            <dbReference type="Rhea" id="RHEA:18737"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16144"/>
            <dbReference type="ChEBI" id="CHEBI:29317"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.9.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="5">Binds 1 Mg(2+) ion per monomer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the selenophosphate synthase 1 family. Class I subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.9.3" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298333.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001589"/>
    <dbReference type="EnsemblBacteria" id="EEZ40562">
        <property type="protein sequence ID" value="EEZ40562"/>
        <property type="gene ID" value="VDA_001589"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0709">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="882590at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004756">
        <property type="term" value="F:selenide, water dikinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016260">
        <property type="term" value="P:selenocysteine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02195">
        <property type="entry name" value="SelD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.650.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00625">
        <property type="entry name" value="SelD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010918">
        <property type="entry name" value="PurM-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036676">
        <property type="entry name" value="PurM-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016188">
        <property type="entry name" value="PurM-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036921">
        <property type="entry name" value="PurM-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023061">
        <property type="entry name" value="SelD_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004536">
        <property type="entry name" value="SPS/SelD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10256">
        <property type="entry name" value="PTHR10256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00586">
        <property type="entry name" value="AIRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02769">
        <property type="entry name" value="AIRS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036407">
        <property type="entry name" value="Selenphspht_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55326">
        <property type="entry name" value="SSF55326"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56042">
        <property type="entry name" value="SSF56042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00476">
        <property type="entry name" value="selD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0711">Selenium</keyword>
    <keyword evidence="2 5 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AIRS" evidence="6">
        <location>
            <begin position="48"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="AIRS_C" evidence="7">
        <location>
            <begin position="167"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="15"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="18"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="46"/>
            <end position="48"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="89"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="137"/>
            <end position="139"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="225"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="5">
        <location>
            <position position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ40562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="344" mass="36350" checksum="86E20254980453F0" modified="2010-01-19" version="1">MENVRLTQYSHGAGCGCKISPQVLDTILRTQIAPFADPNLLVGNESKDDAAVYDLGNGTAVISTTDFFMPIVDDPYDFGRIAATNAISDIYAMGGKPIMAIAILGWPVNVLAPEIAQKVIEGGRAVCRDAGISLAGGHSIDAPEPIFGLAVTGIVDTDRIKRNDKAEAGCKLFLTKPLGIGVLTTAEKKSKLAEEHKGLARDWMCKLNKPGADFADVSGVKALTDVTGFGLLGHLSEICEGSGVKAKVWFDQVPHLPGVFDYIEQGCVPGGTERNFASYGDKIAPMTAEQKALLCDPQTSGGLLLAVAPGSEDEIAEIAKHHNIELQAIGELFEQDGSALIEVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVN7</accession>
    <name>D0YVN7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Sugar diacid utilization regulator SdaR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001202</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CdaR family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297629.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001202"/>
    <dbReference type="EnsemblBacteria" id="EEZ40180">
        <property type="protein sequence ID" value="EEZ40180"/>
        <property type="gene ID" value="VDA_001202"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3835">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1439158at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041522">
        <property type="entry name" value="CdaR_GGDEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008599">
        <property type="entry name" value="Diacid_rec"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025736">
        <property type="entry name" value="PucR_C-HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042070">
        <property type="entry name" value="PucR_C-HTH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05651">
        <property type="entry name" value="Diacid_rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17853">
        <property type="entry name" value="GGDEF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13556">
        <property type="entry name" value="HTH_30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Diacid_rec" evidence="2">
        <location>
            <begin position="3"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF_2" evidence="4">
        <location>
            <begin position="143"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="HTH_30" evidence="3">
        <location>
            <begin position="325"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="385" mass="43727" checksum="64E25704B53817CC" modified="2010-01-19" version="1">MQLNATIARQIVERTMKIIHHSVNVMDEHGRIIGSGDPSRLAQRHEGAILALNDNRVVEIDAPTAIQLKGVKPGINLPILFKQHVIGVVGISGQPDDVRNYGELVKMTAELIVEQAALMSQIQWNKRHREELVLQLIQQTELNEEQLLTIAERLELDLNQPRIAALVKVVPQAGKQLSLEHLQHLVHLLEYPERDNLVGIASVSRNEVVVLKPIKLDSDHKGWSRDLEQKRVDKLIRRIAKEGNFTIRIALGDYFAGLNGLAKSFMTAKATMETADFSHNSNQVLFYQDNILPVLLSGLKDDTWRYQQLSAPLELLAQHDLRGTLLKTLKVYFDQNCDLAQTCQTLHIHRNTLRYRLEKIEQETKLNFNNIADKTRLYLATLSQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVQ8</accession>
    <name>D0YVQ8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001999</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299135.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001999"/>
    <dbReference type="EnsemblBacteria" id="EEZ40967">
        <property type="protein sequence ID" value="EEZ40967"/>
        <property type="gene ID" value="VDA_001999"/>
    </dbReference>
    <dbReference type="GeneID" id="57341860"/>
    <dbReference type="eggNOG" id="COG3204">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1688876at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011044">
        <property type="entry name" value="Quino_amine_DH_bsu"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50969">
        <property type="entry name" value="SSF50969"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019155" evidence="1">
        <location>
            <begin position="19"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="293" mass="33514" checksum="4A56BF910C156D22" modified="2010-01-19" version="1">MKRLFLSLCILATSTACSSSEVHFVRKPLHIDVQADLPVQVNETSGLAVINNRVWTHNDSGGKNEIYQLSPDYKTVTKTVSIKGNKNYDWEDLTQDERYLYVGDTGNNSTRRNGGVIYKLRISDVEKYHSVMPYNVIRYQFKNFHKAKTYQHNFDSEAIASVGDKIWLFSKNWNDEQSQLYVLSKSAQRQLLKPVATYPTAGLITGADYNPQTQTMALVGYRKDMLLGYAFIWLVKVKNDRLDWSTAVYKRLGIYGQWEGIHWDGADKLLLTTEKNPLTKALIGTVDVSFYTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVS1</accession>
    <name>D0YVS1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002012</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299173.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002012"/>
    <dbReference type="EnsemblBacteria" id="EEZ40980">
        <property type="protein sequence ID" value="EEZ40980"/>
        <property type="gene ID" value="VDA_002012"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="637794at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014917">
        <property type="entry name" value="DUF1800"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08811">
        <property type="entry name" value="DUF1800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="512" mass="58198" checksum="D659BC9ABF5C9899" modified="2010-01-19" version="1">MSVHSLYLSKSQNVAFLYRATFGSTLDDVTHLQTIGVQQWFEEQSQRPPSYHLPVIQQATALANLDKPNSTIRTGAWYQHALTAPDQLRQRMAYALSQILVISQQGLGNRHDEIAAYYDLLVQHSLGNFKDLLRDVTTNPMMGRYLTLRGSRKANPKKNSFPDENYAREVMQLFTLGLWRLNNRGEALLDSNGQKIPTYQQDDVQELARVLTGWTGGSLHVPMYGKEKFHDYDEKVVLGQTFPAGQNTQQDLEQAIEVLFNHPNTPPFIANLLIKRFVTSNPRPEYIERVAQTFINNGMGVRGDLKATLFAILTDEDALNSIGSQGNQSTLQQHNHFGLIKEPILMITNQAKALGMSTIGDYWRDFMSSSRTLGQSPLNSETVFNFYLPDFAPQGILEERGLTSPEASLLTTYQMQMIHNKIVQNIESHKNKKSTQWRYDITPFLAVHQDPDAYTQLINERIFLGLMPARVHQQIVEALTLHIPLKQDLRRVKTTLYIAFTAPEFFTQEALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVS7</accession>
    <name>D0YVS7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SLATT_6 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001992</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299114.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40960">
        <property type="protein sequence ID" value="EEZ40960"/>
        <property type="gene ID" value="VDA_001992"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502ZSUK">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1629704at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041119">
        <property type="entry name" value="SLATT_6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18169">
        <property type="entry name" value="SLATT_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="170"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="SLATT_6" evidence="2">
        <location>
            <begin position="1"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="236" mass="26069" checksum="17ACD2A1555819EE" modified="2010-01-19" version="1">MTEQTIKKQVAREYYNVLYSAKLHFASFDICEKLPTMISVISLSFGVLGLAFAEFNSKALAALLLIIGIIGITLKPRELQKGQYEATGVSLTDISKKLEHIYCEIDVQDTESVAKARADLAQAQADHRAVGTMPPVLMSSWYAHYKVFSEHNSDWMSKELELGFNDKVPLSLRAVIIGAIVAALLWLNPLCITSKTWAWVSEPCVGCWQEQLAPGLEPALAKDATPEPKQDSEVAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVU2</accession>
    <name>D0YVU2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">NAD-dependent malic enzyme</fullName>
            <shortName evidence="6">NAD-ME</shortName>
            <ecNumber evidence="6">1.1.1.38</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">maeA</name>
        <name evidence="12" type="ORF">VDA_002023</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>(S)-malate + NAD(+) = CO2 + NADH + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:12653"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.38"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>H(+) + oxaloacetate = CO2 + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:15641"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="EC" id="1.1.1.38"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6 8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="6 8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="6 8">Divalent metal cations. Prefers magnesium or manganese.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6 9">Belongs to the malic enzymes family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.38" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299202.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002023"/>
    <dbReference type="EnsemblBacteria" id="EEZ40991">
        <property type="protein sequence ID" value="EEZ40991"/>
        <property type="gene ID" value="VDA_002023"/>
    </dbReference>
    <dbReference type="GeneID" id="57341835"/>
    <dbReference type="eggNOG" id="COG0281">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="654531at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004471">
        <property type="term" value="F:malate dehydrogenase (decarboxylating) (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008948">
        <property type="term" value="F:oxaloacetate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01619">
        <property type="entry name" value="NAD_malic_enz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015884">
        <property type="entry name" value="Malic_enzyme_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012301">
        <property type="entry name" value="Malic_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037062">
        <property type="entry name" value="Malic_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012302">
        <property type="entry name" value="Malic_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001891">
        <property type="entry name" value="Malic_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023667">
        <property type="entry name" value="NAD_malic_enz_proteobac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00390">
        <property type="entry name" value="malic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03949">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000106">
        <property type="entry name" value="ME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00072">
        <property type="entry name" value="MALOXRDTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01274">
        <property type="entry name" value="malic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00919">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00331">
        <property type="entry name" value="MALIC_ENZYMES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0520">NAD</keyword>
    <keyword evidence="4 6 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="malic" evidence="11">
        <location>
            <begin position="78"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="Malic_M" evidence="10">
        <location>
            <begin position="268"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6 7">
        <location>
            <position position="101"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6 7">
        <location>
            <position position="172"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 8">
        <location>
            <position position="243"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 8">
        <location>
            <position position="244"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 8">
        <location>
            <position position="267"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="415"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for activity" evidence="6">
        <location>
            <position position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000106-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000106-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ40991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="562" mass="62883" checksum="5F87CB7EB4BFFC18" modified="2010-01-19" version="1">MNYNKRPLYIPYAGPALLETPLLNKGSAFSVEERMFFNLEGLLPEAIETIEEQEERAYQQYMMFDNDLDKHIYLRNIQDTNETLFYRLVQNHISEMMPIIYTPTVGAACENFSNIYRRGRGLFISYPNRDRIEEMLNNASRQNVKVIVVTDGERILGLGDQGIGGMGIPIGKLSLYTACGGISPAYTLPVVLDVGTNNPQRLSDPMYMGWRHTRVTGPEYEKFVDEFIQAVKLRWPDALIQFEDFAQKNAMPLLERYKDKVCCFNDDIQGTAAVTVGSLLAACKAAGSKLSEQRVTFLGAGSAGCGIAEAIIAQMVSEGISDEQARSQVFMVDRWGLLLDGMPNLLNFQQALVQKHHNISDWDVADNNISLLDVMRNAKPTVLIGVSGVPGLFSEEVIKEMHAHCPRPIIFPLSNPTSRVEATPFDLIRWTDGNALVATGSPFEPVVYNGKTYPIAQCNNSYIFPGIGLGVLAVNARRVTDQMLQESSRALAECSPLAIHGHGALLPPLEEIQNVSRKIAFAVAKKAVEQHKAPKKSDERIREKIEDNYWTSEYRRYKRTSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVW5</accession>
    <name>D0YVW5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribose-5-phosphate isomerase A</fullName>
            <ecNumber evidence="2">5.3.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Phosphoriboisomerase A</fullName>
            <shortName evidence="2">PRI</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rpiA</name>
        <name evidence="3" type="ORF">VDA_001246</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>aldehydo-D-ribose 5-phosphate = D-ribulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:14657"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="ChEBI" id="CHEBI:58273"/>
            <dbReference type="EC" id="5.3.1.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate degradation; pentose phosphate pathway; D-ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ribose 5-phosphate isomerase family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.6" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297720.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001246"/>
    <dbReference type="EnsemblBacteria" id="EEZ40224">
        <property type="protein sequence ID" value="EEZ40224"/>
        <property type="gene ID" value="VDA_001246"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0120">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1681738at2"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00412"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004751">
        <property type="term" value="F:ribose-5-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009052">
        <property type="term" value="P:pentose-phosphate shunt, non-oxidative branch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01398">
        <property type="entry name" value="RPI_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00170">
        <property type="entry name" value="Rib_5P_isom_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020672">
        <property type="entry name" value="Ribose5P_isomerase_typA_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004788">
        <property type="entry name" value="Ribose5P_isomerase_type_A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11934">
        <property type="entry name" value="PTHR11934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06026">
        <property type="entry name" value="Rib_5-P_isom_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00021">
        <property type="entry name" value="rpiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="28"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="81"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="94"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="103"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="219" mass="23196" checksum="5FD698F11C925158" modified="2010-01-19" version="1">MTQDEMKKAAGWAALEYVKKGSIVGVGTGSTVNHFIDALATRKEEIKGAVSSSVASTERLKQIGIPVFDANEVASLDIYVDGADEINGEFDMIKGGGAALTREKIVAAIAKTYVCIVDNTKEVDVLGQFPLPVEVIPMARSYVARELVKLGGDPVYRQGVTTDNGNIILDVHNMQITNPKAMEDAINGIAGVVTVGLFAHRGADILLVGAPDGVKKVEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW44</accession>
    <name>D0YW44_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_001326</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0126 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297863.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001326"/>
    <dbReference type="EnsemblBacteria" id="EEZ40301">
        <property type="protein sequence ID" value="EEZ40301"/>
        <property type="gene ID" value="VDA_001326"/>
    </dbReference>
    <dbReference type="GeneID" id="57339774"/>
    <dbReference type="eggNOG" id="COG2860">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1665397at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005115">
        <property type="entry name" value="Gly_transporter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03458">
        <property type="entry name" value="Gly_transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="90"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="117"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="150"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="174"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="Gly_transporter" evidence="8">
        <location>
            <begin position="5"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="Gly_transporter" evidence="8">
        <location>
            <begin position="93"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ40301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="204" mass="22551" checksum="49220AD514659D35" modified="2010-01-19" version="1">MFVHIIELICICAFALSAVISEANRGKDIISVLVLGWVTALGGGTVRDVILSTDQVFWIKDPSYFWAALISSLIGFFIAGSLRKLKAERLIIVLDAIGISMFSVLVTKNMIHQDYAAYVAITMGMVTAVFGGVVRDIIVNRPTMFNNTEFYATPVILGCTLFVVFSHLGMNADINTIICIALIIFLRMYIVVKKKTFPSYLLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW45</accession>
    <name>D0YW45_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Glutamate decarboxylase</fullName>
            <ecNumber evidence="3 9">4.1.1.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_001327</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Converts glutamate to gamma-aminobutyrate (GABA), consuming one intracellular proton in the reaction. The gad system helps to maintain a near-neutral intracellular pH when cells are exposed to extremely acidic conditions. The ability to survive transit through the acidic conditions of the stomach is essential for successful colonization of the mammalian host by commensal and pathogenic bacteria.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>H(+) + L-glutamate = 4-aminobutanoate + CO2</text>
            <dbReference type="Rhea" id="RHEA:17785"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:59888"/>
            <dbReference type="EC" id="4.1.1.15"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 7 8">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the group II decarboxylase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.15" evidence="3 9"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297864.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001327"/>
    <dbReference type="EnsemblBacteria" id="EEZ40302">
        <property type="protein sequence ID" value="EEZ40302"/>
        <property type="gene ID" value="VDA_001327"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0076">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1478871at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004351">
        <property type="term" value="F:glutamate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006536">
        <property type="term" value="P:glutamate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010107">
        <property type="entry name" value="Glutamate_decarboxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002129">
        <property type="entry name" value="PyrdxlP-dep_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021115">
        <property type="entry name" value="Pyridoxal-P_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43321">
        <property type="entry name" value="PTHR43321"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00282">
        <property type="entry name" value="Pyridoxal_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01788">
        <property type="entry name" value="Glu-decarb-GAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00392">
        <property type="entry name" value="DDC_GAD_HDC_YDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="5 8 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="7">
        <location>
            <position position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602129-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ40302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="466" mass="52790" checksum="65380AEB8B435D76" modified="2010-01-19" version="1">MAIHEVNREQGADPIFGSDALSHIASSKKMPQQEQSPQAIYQMIRDELYLDGNARQNLATFCQTWEEDEVHKLMDLSIDKNMIDKDEYPQSAEIENRCVHILADLWNSPDSVTTIGTSTTGSSEACMLGGLAALWRWRAKRQAEGQPTDKPNMVCGPVQVCWEKFARYWDIEMRQTKMDDGHYMMTPEDMLELVDANTIMVVPTFGQTFTGLYETVKPLSDALDTYEHDTGNSIDIHVDGASGGMLAPFCATDIEPWDFRLERVKSISTSGHKFGLAPVGCGWVVWRSKEDLPEGLIFHVNYLGGDMPTFALNFSRPAGQIIAQYYDFLRLGYEGYQRIHNSSYDVCRYLVQELNKFDLFEFIFDGNPKKGIPAISWRLKDHANVSFSLYDLADRLRTRGWLVPAYSLPANAQNIVVQRILVKQGFSQDLANLLIKDFTRSIEFLQTHGTTKCSEADVKSFDHSGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW56</accession>
    <name>D0YW56_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Amino-acid acetyltransferase</fullName>
            <ecNumber evidence="8">2.3.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">N-acetylglutamate synthase</fullName>
            <shortName evidence="8">AGS</shortName>
            <shortName evidence="8">NAGS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">argA</name>
        <name evidence="10" type="ORF">VDA_001338</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>acetyl-CoA + L-glutamate = CoA + H(+) + N-acetyl-L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24292"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:44337"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.1.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 1/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the acetyltransferase family. ArgA subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.1" evidence="8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297878.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001338"/>
    <dbReference type="EnsemblBacteria" id="EEZ40313">
        <property type="protein sequence ID" value="EEZ40313"/>
        <property type="gene ID" value="VDA_001338"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0548">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1246">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="901370at2"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00106"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004042">
        <property type="term" value="F:acetyl-CoA:L-glutamate N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103045">
        <property type="term" value="F:methione N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04237">
        <property type="entry name" value="AAK_NAGS-ABP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01105">
        <property type="entry name" value="N_acetyl_glu_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033719">
        <property type="entry name" value="NAGS_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010167">
        <property type="entry name" value="NH2A_AcTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30602">
        <property type="entry name" value="PTHR30602"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000423">
        <property type="entry name" value="ArgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01890">
        <property type="entry name" value="N-Ac-Glu-synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4 8" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="9">
        <location>
            <begin position="295"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ40313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="441" mass="48976" checksum="7FA7DB180C62C43D" modified="2010-01-19" version="1">MKLRSMALVKGFRQSAPYLNAHIGKTMVIMLGGEAIYDRNFNHIVNDLALLNRLGIKLVIVYGARPQISDLLAQHDYATPYHKGIRITDNRALEIAKQAAGQLQLDITARFSMGLNNTPMAGSQINVISGNFIIAQPLGIDDGIDYCHSGRIRRIDITGIERQLTQGSIVLLGPIASSVTGECFNLMSEEIATQLAIRLQADKLIGFCSEQGVLNSQGEVHSELLPNEAEYCLEQLTQQQADNTGTARFLRGAITACRAGVPRSHLISYKEDGALIQELFSLDGIGTQIVMASAEKLRSANIDDIGGILDLIRPLEQEGILVRRSREQLEQEINQFTIIEKDGLVIGCAALYPFPDEQMAEMACVAIHPDYRDADRGVVLLQRLCQQARTLQLTYLFVLTTRSLHWFLEQGFVESDIDTLPVAKKALYNFQRRSKILRLKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW81</accession>
    <name>D0YW81_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Outer membrane protein assembly factor BamA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">bamA</name>
        <name evidence="8" type="ORF">VDA_001366</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the Bam complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the BamA family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297930.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001366"/>
    <dbReference type="EnsemblBacteria" id="EEZ40341">
        <property type="protein sequence ID" value="EEZ40341"/>
        <property type="gene ID" value="VDA_001366"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4775">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="258122at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043165">
        <property type="term" value="P:Gram-negative-bacterium-type cell outer membrane assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051205">
        <property type="term" value="P:protein insertion into membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01430">
        <property type="entry name" value="OM_assembly_BamA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000184">
        <property type="entry name" value="Bac_surfAg_D15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010827">
        <property type="entry name" value="BamA/TamA_POTRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039910">
        <property type="entry name" value="D15-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023707">
        <property type="entry name" value="OM_assembly_BamA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034746">
        <property type="entry name" value="POTRA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12815">
        <property type="entry name" value="PTHR12815"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12815:SF23">
        <property type="entry name" value="PTHR12815:SF23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01103">
        <property type="entry name" value="Omp85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07244">
        <property type="entry name" value="POTRA"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006076">
        <property type="entry name" value="OM_assembly_OMP85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03303">
        <property type="entry name" value="OM_YaeT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51779">
        <property type="entry name" value="POTRA"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 6" id="KW-1134">Transmembrane beta strand</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5009009101" description="Outer membrane protein assembly factor BamA" evidence="6">
        <location>
            <begin position="21"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="domain" description="POTRA" evidence="7">
        <location>
            <begin position="25"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="POTRA" evidence="7">
        <location>
            <begin position="93"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="POTRA" evidence="7">
        <location>
            <begin position="176"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="POTRA" evidence="7">
        <location>
            <begin position="267"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="POTRA" evidence="7">
        <location>
            <begin position="348"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ40341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="807" mass="90150" checksum="E8D7B0368FF2F77D" modified="2010-01-19" version="1" precursor="true">MAMKKLLVASLLLGSSVAHSAEQNFVVDDIRFEGLQRVTLGAALLKMPVRVGDTVDSQDVSSLIRSLYASGNFEDVQVYRDGNTLIIQVHERPTIASITFAGNKAIKEDQLKENLNSADLRVGEALDRTTLSKIEKGLEDFYYSVGKYNATVEAVVTPLPRNRVDLKFVFTEGVSAKIKQINILGNHVFSDADIRSKFNLKANVPWWNFMANEKYQKQVLAGDLEALRTMYLNDGYLKYRLDSTQVSISPDKKGVYITLKVHEGEQYKVKSVQFRGDTVNSQAELDKLVDFKAGDVYNGAKVTALEEAVKRKLGEAGYAYPQVQTIPEFDDATKEVSLVVNIDPGKRVYVRKIEFAGNASTKDEVLRREMRQMEGTWLNAKNIETGKQRLNRTGFFENVDVETVRVPGSDDQVDVRYKVKEANAGSVNFGVGYGTESGISFQAGLTQDNFLGTGNRFGINAMMNDYQKNVSLEYKDPYFTIDGISLGGKVYYNEFEASNANISDYTNQSYGTSLTWGFPFNELNFFDFGLGYDHNKISNTQEYYQIEKFKRAHGFDRDDGSIVLDDFYWSASWTRNNLNRGYFPTSGNYQRASLRMTIPGSDAQYYKAQYDVRQYIPLTQSQDFSLLLRGRLGYGNGYGKTDNGSDQLLPFYENFYAGGFSTLRGFRSNTVGPKAVYVGGCPAGGGISGNNNCYTGTDDAAGGNAQALASMELIVPTPFVSEEFRNQIRTSIFVDAGTVWDTEYDLKDSSGKYLYDYSDPGMIRASYGAALQWMSPMGPLVFSLAKPIKKYDGDDEELFTFTIGQTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWE2</accession>
    <name>D0YWE2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Permease PerM</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_001413</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298020.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40387">
        <property type="protein sequence ID" value="EEZ40387"/>
        <property type="gene ID" value="VDA_001413"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0628">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="944044at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002549">
        <property type="entry name" value="AI-2E-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21716">
        <property type="entry name" value="PTHR21716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01594">
        <property type="entry name" value="AI-2E_transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="68"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="156"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="220"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="251"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="279"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="307"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="359" mass="39620" checksum="95B64771354453D3" modified="2010-01-19" version="1">MIDMLNRWYKRRFSDPHAVSLVMILLGGFLTIYFFGHLIAPLLVAIVLAYLLEWPVMRLNRLGMPRTIAVAVVLVLFAGLMVMAIFGLVPTIWHQVSNLLADVPNMFNGFQNYISSLPERYPEFVQPHQVGMFMDTLKGKVLGLGESVVKGSLSSLVSLATLGVYLILVPLLVFFLLKDKEEMLNMLRGLLPKNRRLASKVGVEMNEQISNYIRGKVTEIFIVGIVSYITFVLLGLQYAVLLGVLVGLSVLIPYIGAAAVTVPVAMVALFQWGLTPEFWWLLVAYGIIQALDGNVLVPILFSEAVNLHPVAIIVAVLVFGGLWGFWGVFFAIPLATLVKAVWGALPDLEPISSDYSAKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWE7</accession>
    <name>D0YWE7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Hydroxyacylglutathione hydrolase</fullName>
            <ecNumber evidence="5">3.1.2.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Glyoxalase II</fullName>
            <shortName evidence="5">Glx II</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">gloB</name>
        <name evidence="7" type="ORF">VDA_001395</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>an S-(2-hydroxyacyl)glutathione + H2O = a 2-hydroxy carboxylate + glutathione + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21864"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:58896"/>
            <dbReference type="ChEBI" id="CHEBI:71261"/>
            <dbReference type="EC" id="3.1.2.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Secondary metabolite metabolism; methylglyoxal degradation; (R)-lactate from methylglyoxal: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.6" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297992.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001395"/>
    <dbReference type="EnsemblBacteria" id="EEZ40370">
        <property type="protein sequence ID" value="EEZ40370"/>
        <property type="gene ID" value="VDA_001395"/>
    </dbReference>
    <dbReference type="GeneID" id="57339685"/>
    <dbReference type="eggNOG" id="COG0491">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="733552at2"/>
    <dbReference type="UniPathway" id="UPA00619">
        <property type="reaction ID" value="UER00676"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004416">
        <property type="term" value="F:hydroxyacylglutathione hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019243">
        <property type="term" value="P:methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07723">
        <property type="entry name" value="hydroxyacylglutathione_hydrolase_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01374">
        <property type="entry name" value="Glyoxalase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035680">
        <property type="entry name" value="Clx_II_MBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032282">
        <property type="entry name" value="HAGH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017782">
        <property type="entry name" value="Hydroxyacylglutathione_Hdrlase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16123">
        <property type="entry name" value="HAGH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005457">
        <property type="entry name" value="Glx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03413">
        <property type="entry name" value="GSH_gloB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Lactamase_B" evidence="6">
        <location>
            <begin position="12"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="128"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="252" mass="27931" checksum="04029CAA65E6B16E" modified="2010-01-19" version="1">MLTVQSIPAFKDNYIWLLQSPEKHCIVIDPGDAKPVIEAIEKQQLTLDAILITHHHNDHCGGISELKRRYPSINVVGPQNDPIPGLTQSVEDGDQVDIFGERFMVLAVPGHTHGHVAYVGDEKLFCGDTLFSAGCGRIFEGTPEEMYASLQKIAALPDETEIYCAHEYTAGNIAFALVAEQDNPHLQRYREEVNRLRANGESTLPSTLGKEKLVNPFLRCDQPSIKKAVADKATDSSDLATFTALRSWKDDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWI6</accession>
    <name>D0YWI6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001228</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the YggT family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297682.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001228"/>
    <dbReference type="EnsemblBacteria" id="EEZ40206">
        <property type="protein sequence ID" value="EEZ40206"/>
        <property type="gene ID" value="VDA_001228"/>
    </dbReference>
    <dbReference type="GeneID" id="57339894"/>
    <dbReference type="eggNOG" id="COG0762">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1692876at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003425">
        <property type="entry name" value="CCB3/YggT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33219">
        <property type="entry name" value="PTHR33219"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02325">
        <property type="entry name" value="YGGT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="61"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="158"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="185" mass="20901" checksum="A6C5BDB03E86B31B" modified="2010-01-19" version="1">MNSIGFLVQTVFNLYIMVVLLRVWLQWSRADFYNPFSQFVVKATQPVIAPLRRVIPSIGSVDMATLLFAYVLSVLKFVLLQMIFTGGNMLFSPDFLWIGLLSMIKAAGGLLFWVLLIRAIMSWVSQGRSPIEYVMHQLTEPLTAPIRRVIPAMGGLDLSVLVLFLALQFANYLMGDLIGPIWFQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWM4</accession>
    <name>D0YWM4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001515</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298195.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001515"/>
    <dbReference type="EnsemblBacteria" id="EEZ40489">
        <property type="protein sequence ID" value="EEZ40489"/>
        <property type="gene ID" value="VDA_001515"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="186"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="227"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="260"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="307"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="335" mass="38711" checksum="08AB062281C0349D" modified="2010-01-19" version="1">MIYYSLAVFWAYIILLAIRLPVSIRALLMIPLVVFSTYRGESGPDTENYIYRFHNLSDYFNSFNISSEPLISCLMYIAKLFDENNVIIFNLLYSILLCTLFIFITKRYSISRPFLLTFGVFLLIDGLTNTLRASMCYFLFVTSVCYENNSYKLRLLAFLSHVSTIILIFFHVFFKKVKIELNINGVIKLSIYIVLFGIGIFFWEYIINIFPRIADKVEAYKTLYTRSLFSGLSDIFVIGSLLLVGSVFNRTTHKEILRDIVVIIILLYILFSFASLSIGMLRVLKIIAICLSLSPMIVLSKRRIPSYIFVIIGGLYILNYLRIIYTSSGYLPYGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWS5</accession>
    <name>D0YWS5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001470</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0319 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298119.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001470"/>
    <dbReference type="EnsemblBacteria" id="EEZ40444">
        <property type="protein sequence ID" value="EEZ40444"/>
        <property type="gene ID" value="VDA_001470"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3110">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1830086at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018635">
        <property type="entry name" value="UPF0319"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38108">
        <property type="entry name" value="PTHR38108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09829">
        <property type="entry name" value="DUF2057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019175" evidence="2">
        <location>
            <begin position="22"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="237" mass="25896" checksum="103D814FBADF5191" modified="2010-01-19" version="1">MKKMTQLVYATLFLSSYAVQANVSLEMPAHFSVLAAQSQELKKAQKQINLADGQQRVLIRFESPRNPHSTAQSMGYIHSQPLLVSFSAQNDAIKLVAPRIDTPQEIVKFAKAPKFDLIDGKGQSIKYSVETMNFSGSPLLADYNALLAEFITPKAEPVTAMGSQKAISASHKIAVAPIVTSATIVGSTSVSAASSKTVIPIEVSKLSPTQRQELLRSLYQQADETQRKEFMRWALGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWT3</accession>
    <name>D0YWT3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidase U32</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001478</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298129.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001478"/>
    <dbReference type="MEROPS" id="U32.003"/>
    <dbReference type="EnsemblBacteria" id="EEZ40452">
        <property type="protein sequence ID" value="EEZ40452"/>
        <property type="gene ID" value="VDA_001478"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0826">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1264653at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071704">
        <property type="term" value="P:organic substance metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020988">
        <property type="entry name" value="Pept_U32_collagenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001539">
        <property type="entry name" value="Peptidase_U32"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12392">
        <property type="entry name" value="DUF3656"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01136">
        <property type="entry name" value="Peptidase_U32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01276">
        <property type="entry name" value="PEPTIDASE_U32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3656" evidence="1">
        <location>
            <begin position="402"/>
            <end position="516"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="631" mass="70657" checksum="10585F032B201B94" modified="2010-01-19" version="1">MTSASELSTTPLGHISNCIELLAPAKNADFGIEAIKHGADAVYIGGPAFGARAAAGNSIEDIQRLCEFAHRYHAQVFVALNTILSDSELAQAEQLIWDIYHAGADALIVQDMGILQLNLPPLALHASTQIDNRDKEKAEFLEQVGFTQVVLARELSLPQIYDIAAHTNMQIEFFIHGALCVSYSGQCYISHAFTNRSANRGSCSQMCRLPCNLKTRQGEVLAENQHLLSLKDNNQTANLEALIDAGVRSFKIEGRLKDLSYVKNVTAHYSRELDAIMARRPELYSSSHGRVETNFNADPDKSFNRGKTDYFVQERNAGISDFRTPKYLGQKAGKVRLVGKDFIELDSDLEFNNGDGIAYFSQNYLKVQQSDDKLQGIRVNRADGNRLYFAQMPKDLKVGMVVYRNFDKAFEDLLAKDSSRRRIGVSMILADSHRGLMLTLTDDYGFSAQVEFECEKTPANDAEKTLANIRKQLNKLGNTDFEARDIQVKTSQMWFTPASVLNGLRRDGIAALEQARFEGYQRPAPGKYNPDVEFPKRHLSYLGNVANTSAKAFYQQHGVIEVEDAYELNKVYEDVPLMITKHCLRFSFNQCPKQVEGIKAEPMILEMGGETLKLVFDCLKCEMKVVGHNKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX22</accession>
    <name>D0YX22_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Succinylglutamate desuccinylase</fullName>
            <ecNumber evidence="5">3.5.1.96</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">astE</name>
        <name evidence="6" type="ORF">VDA_001887</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Transforms N(2)-succinylglutamate into succinate and glutamate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>H2O + N-succinyl-L-glutamate = L-glutamate + succinate</text>
            <dbReference type="Rhea" id="RHEA:15169"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:58763"/>
            <dbReference type="EC" id="3.5.1.96"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Amino-acid degradation; L-arginine degradation via AST pathway; L-glutamate and succinate from L-arginine: step 5/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.96" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298880.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001887"/>
    <dbReference type="EnsemblBacteria" id="EEZ40855">
        <property type="protein sequence ID" value="EEZ40855"/>
        <property type="gene ID" value="VDA_001887"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2988">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="632656at2"/>
    <dbReference type="UniPathway" id="UPA00185">
        <property type="reaction ID" value="UER00283"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009017">
        <property type="term" value="F:succinylglutamate desuccinylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019544">
        <property type="term" value="P:arginine catabolic process to glutamate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019545">
        <property type="term" value="P:arginine catabolic process to succinate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd03855">
        <property type="entry name" value="M14_ASTE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00767">
        <property type="entry name" value="Arg_catab_AstE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007036">
        <property type="entry name" value="Aste_AspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016681">
        <property type="entry name" value="SuccinylGlu_desuccinylase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04952">
        <property type="entry name" value="AstE_AspA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017020">
        <property type="entry name" value="AstE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0056">Arginine metabolism</keyword>
    <keyword evidence="3 5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0862">Zinc</keyword>
    <feature type="active site" evidence="5">
        <location>
            <position position="223"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="343" mass="38942" checksum="03E1EAF5BF433AD6" modified="2010-01-19" version="1">MTYTDWVQRGQWLAATCDMSLPFTQEEWTLPSGILCRSLDRGILEFNPPQLPAQTKDIILSSGVHGNETSPIELLDRLVRDIMAGRLELSHRLLVMIAHPTAINNQTRFIEENLNRLFQVKNEPRNLECDIANNLQDIVSNFYGRSTAVAPERWHLDLHCAIRKSQHYRFALSPFTDKPTRSASLFSFIQQANLDAVLLSNRPSSTFSWHSAEYFGAQALTIELGQVAPLGRNDLTQLDDFDRAMRLLVSEPQLVETKWDSNKTPVYRVNRTLIKQSSDFFFLFPTDVPNFTFFDEGEHIGGDGETQFYIEQGGEAIVFPNPDVAIGQRAVLLVKPTSIEEIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX72</accession>
    <name>D0YX72_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hypothetical ribosomal-protein-serine acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001856</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298825.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001856"/>
    <dbReference type="EnsemblBacteria" id="EEZ40824">
        <property type="protein sequence ID" value="EEZ40824"/>
        <property type="gene ID" value="VDA_001856"/>
    </dbReference>
    <dbReference type="GeneID" id="57342022"/>
    <dbReference type="eggNOG" id="COG1670">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1538300at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="20"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="183" mass="20976" checksum="E8144F22E550EE7D" modified="2010-01-19" version="1">MTQHFTLETERLYLRPFKDVDLFPFLQALYDSMAELSPWLEWCDYNFTQDDAKEWIANSSVAWQTNTGYEFAVFDKRSDELLGAVALTCLQPLFNSANLGYWIHSSYHHQGIAKEACQAIIHFGFEDLSLTRLEIVTHMDNIPSQQTALACGAQFEAISRNRVLVNDIPNPGYVYSIIPQDVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXB6</accession>
    <name>D0YXB6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA translocase FtsK</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_001656</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FtsK/SpoIIIE/SftA family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001656"/>
    <dbReference type="EnsemblBacteria" id="EEZ40629">
        <property type="protein sequence ID" value="EEZ40629"/>
        <property type="gene ID" value="VDA_001656"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1674">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041027">
        <property type="entry name" value="FtsK_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002543">
        <property type="entry name" value="FtsK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018541">
        <property type="entry name" value="Ftsk_gamma"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17854">
        <property type="entry name" value="FtsK_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09397">
        <property type="entry name" value="FtsK_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01580">
        <property type="entry name" value="FtsK_SpoIIIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00843">
        <property type="entry name" value="Ftsk_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50901">
        <property type="entry name" value="FTSK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="8" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FtsK" evidence="7">
        <location>
            <begin position="528"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="25"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="277"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="870"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="277"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="545"/>
            <end position="552"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ40629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="889" mass="95286" checksum="E570F395AF62F73F" modified="2010-01-19" version="1">MPYAQVLADIDDDLDADDALLASYSEPTLDLDDDKESIARQEPTWAPESTPTIVMPQRQNVAPTSQQAQSVVQQESVIAPVVTAATVASTVTHAQQPSTTPAVQQVATPSVATAPQSDFNAAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQQEMVSQHVQPAPSQPEVSTAVASAVAANMTQQPDVQAMVVPQAAPLMNEYDETTELPASAPITSTSQAKGLTVAELERELERDEDFTVYVDEETQQTIDSVASESAATPTPNAYAAASQGYETVPQPAEPRPQPATTFEPTQEFISTPEIGAQDGLSELDRAELAAEDVDDVAAAELSDEEAFLKRIRDAQKEQAHLAGLDNPFLMQKEPDLPTPTTPMPTVDLLQPARQTVEPASEEELMRIARLVESKLADYKIKAQVKGVYPGPVITRYELDLAPGVKVSRISGLAKDLARALSATAVRVVEVIPGKPYIGLELPNKSRETVYLSEVISSEKFQNKHGALPIVLGNDISGEAVVADLSKMPHLLVAGTTGSGKSVGVNVMILSLLYKCKPEDCRFIMIDPKMLELSIYEGIPHLLTEVVTDMKDAGNALRWCVGEMERRYKLMAACGVRNLAGYNAKLEEAAAAGHPIHDPLWRPGDSMDEYPPLLEKMPSIVVIVDEFADLMMVVGKKVEELIARLAQKARAAGIHLVLATQRPSVDVITGLIKANIPTRMAFTVSTKTDSRTILDQGGAESLLGMGDMLYLPPGQSHTIRVHGAFASDDDVHNVVNDWKARGKPQYIDGILKSDQGAEGLLPGETGTGGDDDLDQLFDEVAAFVAETRRGSVSGVQRRFKIGYNRAARIVEQLEAHGIVSAPGHNGNREVLAPPPVPQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXC0</accession>
    <name>D0YXC0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001660</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298465.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40633">
        <property type="protein sequence ID" value="EEZ40633"/>
        <property type="gene ID" value="VDA_001660"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031S1S">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1246730at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="289" mass="34074" checksum="E14C1024F4FD78BB" modified="2010-01-19" version="1">MVLSIIISLFIFTVCCGYVIYLYNRESQDLQQQFNQIIGLRQLIFLLRFHRRESHNRLLKPTEKQLNIEQPLPESIAIQSLLLSLLGQAEHQHRPMFRLLKQRTLPILEEWPSYSIARNQAVHGKAIRHVFYLIDDLVTQALLSADQEELFKQYQLAWPMILNALDSLARFRCDIELTSKPKQHYYQSLQIQLKVIERRLKQVSLIQQHQLPSIAFDDLEYKFNQLKHSDKQPIDAQQSLYFLSQQISDFIFTLFDLMLKDIAQSLDVRMPDIAPQQQPNIFTLQSNKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXE0</accession>
    <name>D0YXE0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ion-translocating oxidoreductase complex subunit B</fullName>
            <ecNumber evidence="5">7.-.-.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Rnf electron transport complex subunit B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rnfB</name>
        <name evidence="9" type="ORF">VDA_001619</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5 6">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="5 6">Binds 3 [4Fe-4S] clusters.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="7.-.-.-" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298386.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001619"/>
    <dbReference type="EnsemblBacteria" id="EEZ40592">
        <property type="protein sequence ID" value="EEZ40592"/>
        <property type="gene ID" value="VDA_001619"/>
    </dbReference>
    <dbReference type="GeneID" id="57342303"/>
    <dbReference type="eggNOG" id="COG2878">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1619561at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00463">
        <property type="entry name" value="RsxB_RnfB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007202">
        <property type="entry name" value="4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010207">
        <property type="entry name" value="Elect_transpt_cplx_RnfB/RsxB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016463">
        <property type="entry name" value="RnfB/RsxB_Proteobac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42859:SF3">
        <property type="entry name" value="PTHR42859:SF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04060">
        <property type="entry name" value="FeS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005784">
        <property type="entry name" value="Elect_transpt_RnfB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01944">
        <property type="entry name" value="rnfB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51656">
        <property type="entry name" value="4FE4S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5 6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0249">Electron transport</keyword>
    <keyword evidence="3 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="4 5 6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="4Fe-4S" evidence="8">
        <location>
            <begin position="32"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="7">
        <location>
            <begin position="104"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="7">
        <location>
            <begin position="134"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Hydrophobic" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR005784-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ40592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="192" mass="20302" checksum="8796F126E81D197D" modified="2010-01-19" version="1">MSGILIAVIAIAILAAIFGLILGFASIRFKVEADPIVEQIDAILPQTQCGQCGYPGCRPYAEAVANGEAINKCTPGGQATVEKLADLMGVEADAPAQEEEPLKSVAFIHEDMCIGCTKCIQACPVDAIVGGTKAIHTVIKDECTGCKLCVAPCPTDCIEMITVEETPDTWKWNLNQIPVVNIPVESEADKAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXE2</accession>
    <name>D0YXE2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alpha-aspartyl dipeptidase Peptidase E</fullName>
            <ecNumber evidence="4">3.4.13.21</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001621</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S51 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.13.21" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298390.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40594">
        <property type="protein sequence ID" value="EEZ40594"/>
        <property type="gene ID" value="VDA_001621"/>
    </dbReference>
    <dbReference type="GeneID" id="57342301"/>
    <dbReference type="eggNOG" id="COG3340">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1485646at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016805">
        <property type="term" value="F:dipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03146">
        <property type="entry name" value="GAT1_Peptidase_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005320">
        <property type="entry name" value="Peptidase_S51"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03575">
        <property type="entry name" value="Peptidase_S51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0224">Dipeptidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0720">Serine protease</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="245" mass="26998" checksum="662D0217F7BDBB69" modified="2010-01-19" version="1">MDILLLSNGKIAGNTNIMEFAQSAVIEQIKRTGAKKLVLIPYAVIRSSHDDRVAAVQDSFNSFGLDCEVIGLHQAQDPVKAIEEADGILVSGGNTWVLNKTLHDLGLVGPLRKAVLLDGKPYIGWSAGTNICCPTIRTTNDMPIVTAAVLSSLNFVPFQINPHYLEASVEGHMGETRDERIQEFLEINQHEPVIGIPEGTWLHLLDGKLSYHAANGKKLKLFSYDNEPVYYEQGQDIQFLMSHSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXI1</accession>
    <name>D0YXI1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 10">Acyl carrier protein</fullName>
            <shortName evidence="8">ACP</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">acpP</name>
        <name evidence="12" type="ORF">VDA_001687</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 10">Carrier of the growing fatty acid chain in fatty acid biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Glycolipid biosynthesis; KDO(2)-lipid A biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8 10">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="8">4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.</text>
    </comment>
    <comment type="PTM">
        <text evidence="10">4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the acyl carrier protein (ACP) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298515.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001687"/>
    <dbReference type="EnsemblBacteria" id="EEZ40658">
        <property type="protein sequence ID" value="EEZ40658"/>
        <property type="gene ID" value="VDA_001687"/>
    </dbReference>
    <dbReference type="GeneID" id="57342232"/>
    <dbReference type="eggNOG" id="COG0236">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1943389at2"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="UniPathway" id="UPA00360"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000036">
        <property type="term" value="F:acyl carrier activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036104">
        <property type="term" value="P:Kdo2-lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01217">
        <property type="entry name" value="Acyl_carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003231">
        <property type="entry name" value="Acyl_carrier"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20863">
        <property type="entry name" value="PTHR20863"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00517">
        <property type="entry name" value="acyl_carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="4 8" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 8" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5 8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="1 8 9" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="3 8" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="11">
        <location>
            <begin position="2"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="8 9">
        <location>
            <position position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ40658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="78" mass="8635" checksum="E08F2BCC156E677D" modified="2010-01-19" version="1">MSNIEERVKKIIVEQLGVDESEVKNESSFVDDLGADSLDTVELVMALEEEFDTEIPDEEAEKITTVQAAIDYVNSAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXK9</accession>
    <name>D0YXK9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8">Elongation factor G</fullName>
            <shortName evidence="8">EF-G</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">fusA</name>
        <name evidence="10" type="ORF">VDA_001724</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298582.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001724"/>
    <dbReference type="EnsemblBacteria" id="EEZ40694">
        <property type="protein sequence ID" value="EEZ40694"/>
        <property type="gene ID" value="VDA_001724"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0480">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="88967at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16262">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01434">
        <property type="entry name" value="EFG_mtEFG1_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03713">
        <property type="entry name" value="EFG_mtEFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00054_B">
        <property type="entry name" value="EF_G_EF_2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009022">
        <property type="entry name" value="EFG_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035649">
        <property type="entry name" value="EFG_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004540">
        <property type="entry name" value="Transl_elong_EFG/EF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005517">
        <property type="entry name" value="Transl_elong_EFG/EF2_IV"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03764">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00889">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00484">
        <property type="entry name" value="EF-G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 8 10" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="6 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="9">
        <location>
            <begin position="5"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="14"/>
            <end position="21"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="78"/>
            <end position="82"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="132"/>
            <end position="135"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ40694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="695" mass="76256" checksum="5C46ADC9462822A5" modified="2010-01-19" version="1">MTDLSKYRNIGIFAHVDAGKTTTTERILKLTGKIHKIGDTHDGSTTTDFMEQEAERGITIQSAAVSCFWNDHRLNVIDTPGHVDFTVEVYRSLKVLDGGIGVFCGSGGVEPQSETNWRYANESEVSRLIFVNKLDRMGADFYNVVDQVKNVLGATPLVMTLPIGREEDFVGVVDVLTRQAFVWDDTGLPENYEIKEIPADMIDDVEAYREELVETAVEQDDDLMEAYMEGNEPSIEELKRCIRKGTRDLAFFPTFCGSAYKNKGIQLVLDAVVDYLPAPDEVDPQPLTDPETGEPTGEVATVSADEPFRALAFKIMDDRFGALTFVRIYSGKINKGDTILNAATGKTERVGRMVEMQADERNELTSAQAGDIIAIVGMKNVQTGHTLCDPKHECTLEPMIFPVPVISIAVTPKDKGGSEKMGIAIGKMVAEDPSFQVETDEETGETILKGMGELHLDIKVDILKRTYGVDLIVGQPQVAYRETITTPIEDSYTHKKQSGGSGQFGKIDYRIKPGEQGSGFKFSSSVIGGNVPKEFWPAVEKGFESMMQTGPLAGFPVLDVEVELFDGGFHAVDSSAIAFEIAAKGAFRQSMPKAGPQLLEPIMHVDVFTPEDHVGDVIGDLNRRRGMIRDQQAGATGVRIKGDVPLSEMFGYIGTLRTMTSGRGQFSMEFAHYAPCPANVAEKVIAEQKEKNAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXQ1</accession>
    <name>D0YXQ1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001743</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298611.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001743"/>
    <dbReference type="EnsemblBacteria" id="EEZ40711">
        <property type="protein sequence ID" value="EEZ40711"/>
        <property type="gene ID" value="VDA_001743"/>
    </dbReference>
    <dbReference type="GeneID" id="57342168"/>
    <dbReference type="eggNOG" id="ENOG5033DRY">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2003947at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021379">
        <property type="entry name" value="DUF3012"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012640">
        <property type="entry name" value="Membr_lipoprot_lipid_attach_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11216">
        <property type="entry name" value="DUF3012"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08139">
        <property type="entry name" value="LPAM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="60" mass="6628" checksum="B461CC46F7862194" modified="2010-01-19" version="1">MKKLLVLLGAVALLSACSPKVGSEEWCTQLKEKPKGDWTANEVGEFAKSCIIRFDDQSEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXV7</accession>
    <name>D0YXV7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NAD-dependent protein deacylase</fullName>
            <ecNumber evidence="3">2.3.1.286</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Regulatory protein SIR2 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">cobB</name>
        <name evidence="5" type="ORF">VDA_002120</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>H2O + N(6)-acetyl-L-lysyl-[protein] + NAD(+) = 2''-O-acetyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide</text>
            <dbReference type="Rhea" id="RHEA:43636"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:10731"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17154"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
            <dbReference type="ChEBI" id="CHEBI:83767"/>
            <dbReference type="EC" id="2.3.1.286"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>H2O + N(6)-succinyl-L-lysyl-[protein] + NAD(+) = 2''-O-succinyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide</text>
            <dbReference type="Rhea" id="RHEA:47668"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:11877"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17154"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:87830"/>
            <dbReference type="ChEBI" id="CHEBI:87832"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="3">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="3">2 residues (Tyr-57 and Arg-60) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the sirtuin family. Class III subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.286" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299487.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002120"/>
    <dbReference type="EnsemblBacteria" id="EEZ41088">
        <property type="protein sequence ID" value="EEZ41088"/>
        <property type="gene ID" value="VDA_002120"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1264438at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034979">
        <property type="term" value="F:NAD-dependent protein deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036054">
        <property type="term" value="F:protein-malonyllysine demalonylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036055">
        <property type="term" value="F:protein-succinyllysine desuccinylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006476">
        <property type="term" value="P:protein deacetylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01412">
        <property type="entry name" value="SIRT5_Af1_CobB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01121">
        <property type="entry name" value="Sirtuin_ClassIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003000">
        <property type="entry name" value="Sirtuin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026591">
        <property type="entry name" value="Sirtuin_cat_small_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027546">
        <property type="entry name" value="Sirtuin_class_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026590">
        <property type="entry name" value="Ssirtuin_cat_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02146">
        <property type="entry name" value="SIR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50305">
        <property type="entry name" value="SIRTUIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 3" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Deacetylase sirtuin-type" evidence="4">
        <location>
            <begin position="1"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="112"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="13"/>
            <end position="32"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="94"/>
            <end position="97"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="179"/>
            <end position="181"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="223"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="238" mass="26529" checksum="F6ED0428C520BE29" modified="2010-01-19" version="1">MLFPYRNIVVLTGAGISAESGICTFRSEDGLWENHRVEDVATPEGYERNPELVQNFYNDRRRQIEDGSVAPNAAHLALAQLEREHEGKVTIVTQNIDNLHERAGSVNVIHMHGELLKARCCESGQTVDWHGDLHTSDRCHCCQIPAPMRPDIVWFGEMPIGMDAIHRAICDADLFISIGTSGVVYPAAGFVHEAVLQGLHTVELNLEPSQVQSEFEEKIYGKATQIVPEYIKNTLSIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXX3</accession>
    <name>D0YXX3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4123 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002136</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002136"/>
    <dbReference type="EnsemblBacteria" id="EEZ41104">
        <property type="protein sequence ID" value="EEZ41104"/>
        <property type="gene ID" value="VDA_002136"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031PY9">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025391">
        <property type="entry name" value="DUF4123"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13503">
        <property type="entry name" value="DUF4123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4123" evidence="1">
        <location>
            <begin position="25"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="272" mass="31563" checksum="9A177F4FCC553B5F" modified="2010-01-19" version="1">MQEINNTHKLFDKVITEDLAQGYKLYALMDRSHLINEITEYDQEALFIGTRFKSAIEASPLLISLKLDDTYVVESMMNEYLGILLLSKLSIEQVRETLNQYLEVDSENLGSVYVRFYAPSVCLSLLNSEPELFYGFKVICPQITRKQWVYCDLSKEEIKKRVISISDITVQVMERYRLGAWLGLCERWQQKPSEELHRASIVIESLIKNGLQNQALLEEWRGFLADNLAIIDRPEWNSLLNQSLDDMGLYESAIQLAMVVKQSDDFMVREKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY01</accession>
    <name>D0YY01_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Molybdopterin molybdenumtransferase</fullName>
            <ecNumber evidence="7">2.10.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_002164</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>adenylyl-molybdopterin + H(+) + molybdate = AMP + H2O + Mo-molybdopterin</text>
            <dbReference type="Rhea" id="RHEA:35047"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:36264"/>
            <dbReference type="ChEBI" id="CHEBI:62727"/>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.10.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 7">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 7">Belongs to the MoeA family.</text>
    </comment>
    <dbReference type="EC" id="2.10.1.1" evidence="7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299573.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002164"/>
    <dbReference type="EnsemblBacteria" id="EEZ41132">
        <property type="protein sequence ID" value="EEZ41132"/>
        <property type="gene ID" value="VDA_002164"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0303">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1763">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="651103at2"/>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061599">
        <property type="term" value="F:molybdopterin molybdotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032324">
        <property type="term" value="P:molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00887">
        <property type="entry name" value="MoeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.980.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036425">
        <property type="entry name" value="MoaB/Mog-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001453">
        <property type="entry name" value="MoaB/Mog_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004435">
        <property type="entry name" value="MobB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012182">
        <property type="entry name" value="MobB_MoeA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008284">
        <property type="entry name" value="MoCF_biosynth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038987">
        <property type="entry name" value="MoeA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005111">
        <property type="entry name" value="MoeA_C_domain_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036688">
        <property type="entry name" value="MoeA_C_domain_IV_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005110">
        <property type="entry name" value="MoeA_linker/N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036135">
        <property type="entry name" value="MoeA_linker/N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10192">
        <property type="entry name" value="PTHR10192"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03205">
        <property type="entry name" value="MobB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00994">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03454">
        <property type="entry name" value="MoeA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03453">
        <property type="entry name" value="MoeA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036618">
        <property type="entry name" value="MobB_MoeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00852">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53218">
        <property type="entry name" value="SSF53218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63867">
        <property type="entry name" value="SSF63867"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63882">
        <property type="entry name" value="SSF63882"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00176">
        <property type="entry name" value="mobB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00177">
        <property type="entry name" value="molyb_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01079">
        <property type="entry name" value="MOCF_BIOSYNTHESIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="6 7" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MoCF_biosynth" evidence="8">
        <location>
            <begin position="368"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="594" mass="64689" checksum="F231989E3323C009" modified="2010-01-19" version="1">MSLINASLPLLGFAAFSGTGKTTLLEAMLPKLVEQGLRVAVIKHAHHNFDIDQEGKDSYRLRKAGASQMLISSRFRRALVTETPEVEAELPHLIKQLDQSVLDLILVEGFKAISFPKIELHREEIGKPWLYPDDSNIIAVASDSKPETTLPTLDINDLDAITSFVVNYAKTQYTQKSQEKSLECGDLNPQGMLSVSQGRQAILDQIVPSQTIINVELKDALGQIVAQDILSPVNVPQHTNSAMDGFAIRNDDLDRDSYHVIGQVLAGHSYDLPLEQGQAVRIMTGAPVPKFAGAVVMREQAEVNGENVSFNRNMGVIKAGQNVRMAGEDLALGQVAIAKGTQITAPELGMLASLGFADVAITRPIRVAIFSTGDEVQQPGETQKTNCIYDSNRYTLFALLKKIGCEVVDMGIIEDSEEALEKTLQEASEQADMILSSGGVSVGDADYIKTVLAKLGQINFWRINMRPGRPLAFGQINQIPFFGLPGNPVATMIAFLQFVEPAIRKLQGIDNWQPETITAIAAEKLRSRPGRTEYSRGHYYIDANGRIAVVSTGSQGSGILRSMSEANCLIEIAPEQDNAEIGDSVTIIPLLSRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYC2</accession>
    <name>D0YYC2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002285</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299788.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002285"/>
    <dbReference type="EnsemblBacteria" id="EEZ41253">
        <property type="protein sequence ID" value="EEZ41253"/>
        <property type="gene ID" value="VDA_002285"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502ZC32">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="902721at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021254">
        <property type="entry name" value="DUF2806"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10987">
        <property type="entry name" value="DUF2806"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="277" mass="32199" checksum="ED44C72804151EC4" modified="2010-01-19" version="1">MAETSLIDLKALSEPACKLIDAVSNTIGVLYEPTRIRRKARAESDSLVIMARGESDALALRAARRISTQETRRQENIEGIVDKSINYLDHNNISDGVTIDVDWLSFYFDKCQDISIENVQELWAKILAGEVLEPEACSRSTLLILQSLSNNDIKLFNRYCQFLFRVNGELLRFKYSSLNKHIEKSDIQESDIRHLQDLGLVQPQQQFHFTKNERYVIEYNGYKFAMTLKGHRENRTEFLTKAGRELYRFIEVKPCAKYYEILFSRSQLMARRVKELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYC3</accession>
    <name>D0YYC3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dihydrofolate reductase</fullName>
            <ecNumber evidence="2">1.5.1.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002286</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.5.1.3" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299789.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002286"/>
    <dbReference type="EnsemblBacteria" id="EEZ41254">
        <property type="protein sequence ID" value="EEZ41254"/>
        <property type="gene ID" value="VDA_002286"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0262">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1306955at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008703">
        <property type="term" value="F:5-amino-6-(5-phosphoribosylamino)uracil reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004146">
        <property type="term" value="F:dihydrofolate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002734">
        <property type="entry name" value="RibDG_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01872">
        <property type="entry name" value="RibD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="SSF53597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RibD_C" evidence="1">
        <location>
            <begin position="5"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="177" mass="19782" checksum="4482DB4C588FD8E7" modified="2010-01-19" version="1">MPNIVYIATSLDGYIADKNNQLDWLHDVPNPDGSDFGFAEFMDRVDALIMGRNTVGMVLSFDCEWPYSKPVYVLSNTMKTVPAGYEDKIYLVNGELPTIVEELQQKGLTTLYIDGGKTIQSFLQQDMIDELIITTIPTILGGGIPLFGELDKPLKFKHIKAEQLAGCLVKNTYLRSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYF6</accession>
    <name>D0YYF6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Hexose phosphate uptake regulatory protein UhpC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_002319</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299855.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002319"/>
    <dbReference type="EnsemblBacteria" id="EEZ41287">
        <property type="protein sequence ID" value="EEZ41287"/>
        <property type="gene ID" value="VDA_002319"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2271">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1345431at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021159">
        <property type="entry name" value="Sugar-P_transporter_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000849">
        <property type="entry name" value="Sugar_P_transporter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002808">
        <property type="entry name" value="Hexose_phosphate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00942">
        <property type="entry name" value="GLPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="96"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="157"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="185"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="251"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="281"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="321"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="345"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="378"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="407"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="7">
        <location>
            <begin position="31"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ41287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="443" mass="49541" checksum="65A526228890DC4D" modified="2010-01-19" version="1">MFGFLRSHYPSTMVEDKTEIDQKYHYWRFHIMVSMYIGYAGFYFSRKTFNYAMPAMMADLGLDKADIGLIGTLFYITYGCSKFFSGIISDRSNPRYFMGLGLIATGIINIVFGLSSSLYMLAMLWVLNAWCQGWGWPSCSKLLTTWYSRSERGFWWALWNTAHNVGGALIPLVVGYLTLHFGWRYGFMLPGIIAVVIGLFICWRLRDKPVTLGLPSVGRWRKDHLEIAQENEGLGLSSRDILHKYVIKNKYIWLLAFSYVLVYIVRTGINDWGNLYLTEQFHYSLISANGAISLFEIGGFVGSLVAGWGSDKLFGGNRGPMNLIFAIGIFLSVAALWLMPFKSYVLQSACFFAIGFFIFGPQMLIGMAAAECSHKNSAGAATGFVGLFAYMGAALSGYPLAIVVEHYHWTGFFTVLAAVSAVIGLLLLPFLKAQSVAITQKII</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYI1</accession>
    <name>D0YYI1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Conserved hypothetical transmembrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002344</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299926.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002344"/>
    <dbReference type="EnsemblBacteria" id="EEZ41312">
        <property type="protein sequence ID" value="EEZ41312"/>
        <property type="gene ID" value="VDA_002344"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5542">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1297390at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="186"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="233"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="290"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="338"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="361"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="384" mass="44175" checksum="9199452B1492CF9D" modified="2010-01-19" version="1">MSISTQENIRLNRNIWLTILFAAIVSRIVFYALGLWGVDSFVTGKYAEQPVWQTICRFDCVWFYRIIHDGYDLFPQWLSQNNAANWAFMPLQPFLGWVFSHLAFFDDPIDNARFGLILVSNIAFVISLPLVVMTLKQLKFSENTQYTAIWLLCFSPYTVYSMAGYTEPLFIVFVTAVFLFSYRQQWLWVAVFGLLAAITRNLGVFLVFPVLIIAIQHYGLDTFYRFKTQSVKVIAAIWIIPFGFFSYMTYLYFHTGDALAFGHIQIAWGRQLTNPIHWIIYGFNTGGPKLYLAIASLLAFALNLYLVFNKKYPEALFMFICLVLPLSSSLNAMPRYLFGLYPTFLGLAMIVERYPSVKTPLLCVFSAASCFISIGFFSHIMFTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYI3</accession>
    <name>D0YYI3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Conserved hypothetical membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_002346</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the GRP transporter (TC 2.A.7.5) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299928.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002346"/>
    <dbReference type="EnsemblBacteria" id="EEZ41314">
        <property type="protein sequence ID" value="EEZ41314"/>
        <property type="gene ID" value="VDA_002346"/>
    </dbReference>
    <dbReference type="GeneID" id="57341457"/>
    <dbReference type="eggNOG" id="COG4975">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="934340at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015144">
        <property type="term" value="F:carbohydrate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071705">
        <property type="term" value="P:nitrogen compound transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010651">
        <property type="entry name" value="Sugar_transport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009834">
        <property type="entry name" value="Ureide_permease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16119">
        <property type="entry name" value="PTHR16119"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07168">
        <property type="entry name" value="Ureide_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="81"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="110"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="136"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="169"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="208"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="256"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="282"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="313"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ41314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="333" mass="35322" checksum="C8572EB47FD8CB10" modified="2010-01-19" version="1">MFIVHSYAFAIFMCIITMICWGSWANTTKLVDNKKWPFQLFYWDYAIGILLFSLVFAFTLGSSGTEGRPFITDLMQADLKSIGSALLGGIIFNLSNILLVAAIDLAGMAVAFPIGVGLALVLGVITNYMGNPQGDPIILFAGVACVTVAIILTAIAYSRIQTGDNGNKLKGVITAVLAGVIMGWFFRFVADSMAVDFANPAVGKMTPYTALVIFSVGIFISNFVWNVAVMKKPISGSPVQGDAYFKGSIKEHATGILGGVIWCIGMALSLIASGAAGYAVSYGLGQGATMVAVIWGVFIWREFATAPKGTNKLLSIVFASYILGIILIIAANS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYL1</accession>
    <name>D0YYL1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Arginine decarboxylase catabolic</fullName>
            <ecNumber evidence="5">4.1.1.19</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_002374</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Orn/Lys/Arg decarboxylase class-I family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.19" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299980.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002374"/>
    <dbReference type="EnsemblBacteria" id="EEZ41342">
        <property type="protein sequence ID" value="EEZ41342"/>
        <property type="gene ID" value="VDA_002374"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1982">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="485164at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008792">
        <property type="term" value="F:arginine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00615">
        <property type="entry name" value="Orn_deC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005308">
        <property type="entry name" value="OKR_de-COase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011193">
        <property type="entry name" value="Orn/lys/arg_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000310">
        <property type="entry name" value="Orn/Lys/Arg_deCO2ase_major_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008286">
        <property type="entry name" value="Prn/Lys/Arg_de-COase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036633">
        <property type="entry name" value="Prn/Lys/Arg_de-COase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01276">
        <property type="entry name" value="OKR_DC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03711">
        <property type="entry name" value="OKR_DC_1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03709">
        <property type="entry name" value="OKR_DC_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009393">
        <property type="entry name" value="Orn_decarb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55904">
        <property type="entry name" value="SSF55904"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00703">
        <property type="entry name" value="OKR_DC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OKR_DC_1" evidence="4">
        <location>
            <begin position="389"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="3">
        <location>
            <position position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR009393-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="763" mass="85378" checksum="A85439D32E355CC3" modified="2010-01-19" version="1">MGNYGKQKHVLIFNDNLKTGVIENALHRLLDEFATEGVKVSVATSFDDCYSMLNANIAIDCFMLTSQMTGQQAEENEKFFQLIDKLNRRQQGVPVFLLAERKKITLSVSRELMSRVDEFAWILEDTADFIVGRAVAAMERYRDQLLPPLMAAMMKYDDVHEYSWAAPGHQGGVGFTKTPAGQRFYSYYGEGIFRTDMGIERGSLGSLLDHTGYFGDSEAYAAEVFGAHRSYSLVTGTSGANRTIMQICMKENSLAICDRNCHKSIEQGLMLSGALPVYMVPTRNRYGIIGPIYPEQMTKAAIQKTAKESQLTKDHADQAATYAVITNCTYDGLCYNAKRAQDILGESSNRLHFDEAWYGYARFNPIYENHFAMRGDPVESDNEPTVFATHSTHKLLNALSQASWLHVRHGKDSIDFQRFNQAYMMHATTSPLYAISASNDIAVSQMAGNRGYSLTQEVIREAVDYRQAMGRLYREFEADGDWFFKPWNAETVTDPETGKTIAFEDAAPNLLAESQDFWVMKPGDNWHGFEDMPADWCMLDPIKVSILAPGMGDDGKLLDTGVPAALVTQYLTRFGIVPTRTTDFQVMFLFSMGITKGKWATLVNTLLSFKKHYDNNTPLKSVLPQLANDHPEVYGHMGLKDLGDKMFKYLKDHVPSEKLNAAYSTLPEAVVTPRAAFAEIIDNNVEMVPSHDLAGRVAANAVIPYPPGIPMLMSGESFGDASSPQIGYLRSLEVWDKEFPGFEHETEGTEVEDGVYHVMCIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYP6</accession>
    <name>D0YYP6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Beta-galactosidase</fullName>
            <ecNumber evidence="3 7">3.2.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 7">Lactase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_002409</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.</text>
            <dbReference type="EC" id="3.2.1.23"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the glycosyl hydrolase 2 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.23" evidence="3 7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300038.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002409"/>
    <dbReference type="EnsemblBacteria" id="EEZ41377">
        <property type="protein sequence ID" value="EEZ41377"/>
        <property type="gene ID" value="VDA_002409"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3250">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="245411at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009341">
        <property type="term" value="C:beta-galactosidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004565">
        <property type="term" value="F:beta-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004199">
        <property type="entry name" value="B-gal_small/dom_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036156">
        <property type="entry name" value="Beta-gal/glucu_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006101">
        <property type="entry name" value="Glyco_hydro_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023232">
        <property type="entry name" value="Glyco_hydro_2_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006103">
        <property type="entry name" value="Glyco_hydro_2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023230">
        <property type="entry name" value="Glyco_hydro_2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006102">
        <property type="entry name" value="Glyco_hydro_2_Ig-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006104">
        <property type="entry name" value="Glyco_hydro_2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032312">
        <property type="entry name" value="LacZ_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02929">
        <property type="entry name" value="Bgal_small_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16353">
        <property type="entry name" value="DUF4981"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00703">
        <property type="entry name" value="Glyco_hydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02836">
        <property type="entry name" value="Glyco_hydro_2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02837">
        <property type="entry name" value="Glyco_hydro_2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00132">
        <property type="entry name" value="GLHYDRLASE2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01038">
        <property type="entry name" value="Bgal_small_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49303">
        <property type="entry name" value="SSF49303"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="SSF74650"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00719">
        <property type="entry name" value="GLYCOSYL_HYDROL_F2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00608">
        <property type="entry name" value="GLYCOSYL_HYDROL_F2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7 9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 7 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bgal_small_N" evidence="8">
        <location>
            <begin position="728"/>
            <end position="999"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="1033" mass="118476" checksum="79616DF1AA0D6DE2" modified="2010-01-19" version="1">MNNWENFLHLHENRMAPRAYFFSYDSVQSAKSFQRELSNRFMLLSGQWTFNFFTNPLLVPEEFYSQKMTDWGHITVPNMWQMEGHGDLQYTDEGFPFPIDVPFVPTDNPTGAYQRTFTLGEQWNDKQTIIKFDGVETYFELYVNGQYVGFSKGSRLTAEFDISAYVQQGENLLSVRVMQWADSTYIEDQDMWWTAGIFRDVYLVGKEAVHVQDFTVRTDFADDYQSATLSCSVELENLTHAVATGYQLEYSLQDNGVEVAQGNCSIDDIDANHQVQFAIDMNNPQQWNAENPYLYQLFITLKNSQGQILEVIPQRVGFRDIKVRDGLFYINNQYVMLHGVNRHDNDHLKGRAVGMDRVEKDLILMKQHNINSVRTAHYPNDPRFYELCDIYGLFVMAETDVETHGFANVGDLSRITNDAAWEAVFVDRAERHVHAQKNHPSIIMWSLGNESGYGCNIRSMYAATKAIDDTRLVHYEEDRDAEVVDVISTMYSRAQLMNYFGEHPHEKPRIICEYAHAMGNGPGGLTEYQNVFYAHDHIQGHYVWEWCDHGILARDENGEEFYKYGGDYGDYPNNYNFCMDGLIFPDQTPGPGLKEYKQVIAPVKIRAVDGSNNRFTIENKLWFSDLNDYTITADVRAEGETLRTVQFKVEDLAANSAREITLALPELDERETFVNFTVRKDSRTLYSAANHDIAVYQFLLKENTATAPVFVNHNATELNVAESRLDYTITGHNFALTFSKVNGKLTSWLINGEELIQSEPRLNFFKPMIDNHKQEYEGLWQPAHLQIMQEHFRTLNVETLDGKVVINTTSIIAPPVFDFGMRCHYCYQINAEGQLNIELRGERYGDYPHVIPVIGLDLGINGDFDQVKYYGRGPEENYQDSQQANMIDVYQTNVADMFVNYPFPQNNGNRQHVRWAALTNRHGTGLLVKPQQDINFSAWFCTNENLHAAQHTIELEKSGYITLNLDHQVMGLGSNSWGSEVLDSYRVYMDTFCYGLTLMPLQAGDCSAQAMAAHNFGDAFFTQASTQTSVNEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYX4</accession>
    <name>D0YYX4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Formyltetrahydrofolate deformylase</fullName>
            <ecNumber evidence="3">3.5.1.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Formyl-FH(4) hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">purU</name>
        <name evidence="5" type="ORF">VDA_002487</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>(6S)-10-formyltetrahydrofolate + H2O = (6S)-5,6,7,8-tetrahydrofolate + formate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19833"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
            <dbReference type="EC" id="3.5.1.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Purine metabolism; IMP biosynthesis via de novo pathway; formate from 10-formyl-5,6,7,8-tetrahydrofolate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PurU family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.10" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300186.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002487"/>
    <dbReference type="EnsemblBacteria" id="EEZ41455">
        <property type="protein sequence ID" value="EEZ41455"/>
        <property type="gene ID" value="VDA_002487"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0788">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="979667at2"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008864">
        <property type="term" value="F:formyltetrahydrofolate deformylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016742">
        <property type="term" value="F:hydroxymethyl-, formyl- and related transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08648">
        <property type="entry name" value="FMT_core_Formyl-FH4-Hydrolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01927">
        <property type="entry name" value="PurU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041729">
        <property type="entry name" value="Formyl-FH4-Hydrolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002376">
        <property type="entry name" value="Formyl_transf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036477">
        <property type="entry name" value="Formyl_transf_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004810">
        <property type="entry name" value="PurU"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42706">
        <property type="entry name" value="PTHR42706"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00551">
        <property type="entry name" value="Formyl_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01575">
        <property type="entry name" value="FFH4HYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53328">
        <property type="entry name" value="SSF53328"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00655">
        <property type="entry name" value="PurU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 3" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="3" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACT" evidence="4">
        <location>
            <begin position="5"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="277" mass="31324" checksum="EA66E84EB8544428" modified="2010-01-19" version="1">MEKKTLLTDCSDDLGLIAKITNICHKHQLNIINNKEFVDNTNNQFFMRTELEGYFNDNTFLADLDKALPNGSRRRLINNDRKRIVIMVTKEAHCLGDILVKAFDGTLDVEIAAVVGNYDTLQNLTEKFDIPYHHVSHEGLSREEHEAQLLQTVQQYDPNYVVLAKYMRILTPNFVAAFPHKIINIHHSFLPAFIGAKPYQQAFERGVKIIGATAHFVTNDLDEGPIITQNVIPVDHTFSATEMAKSGRDVEKSVLSKALGLVLDDRVFVHGNRTVIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ34</accession>
    <name>D0YZ34_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hypothetical membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002547</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300300.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002547"/>
    <dbReference type="EnsemblBacteria" id="EEZ41515">
        <property type="protein sequence ID" value="EEZ41515"/>
        <property type="gene ID" value="VDA_002547"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1289">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1451695at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006726">
        <property type="entry name" value="PHBA_efflux_AaeB/fusaric-R"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04632">
        <property type="entry name" value="FUSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="111"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="345" mass="38886" checksum="8AC4EB8E3B83408D" modified="2010-01-19" version="1">MKNLNKTIIKNIRLFNMLRILISCVIAYTIAMFFHIPYIAWAPITIIVVMAANYSGAISHKASQRISGTFLGALLGLSLYLLPETDKILHYTLLLSMLAVTLFFTLGKYSYGAILASVTLVLVAGNGPGDLTIALWRTVNVLWGGLLAILASKFLFPARASYHFKILSGDYLEHFHLVYSQHNQLAHQQEEHEPINLAPLNATLKQLSGLEGSIKHETPNQGNCTKKLIQCYERMFSLLENITQTPWSHQYGHRKIQELDGLFEAKEQLSSCIETLAEHISSEAVLPYVLQQKDLEILALFPTIAGSKEPRTDISFYSYLWLNRELARKLVMVTEYIEAESKLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ35</accession>
    <name>D0YZ35_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Nickel/cobalt efflux system</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">VDA_002548</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Efflux system for nickel and cobalt.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the NiCoT transporter (TC 2.A.52) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300301.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41516">
        <property type="protein sequence ID" value="EEZ41516"/>
        <property type="gene ID" value="VDA_002548"/>
    </dbReference>
    <dbReference type="GeneID" id="57341217"/>
    <dbReference type="eggNOG" id="COG3376">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1515392at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015099">
        <property type="term" value="F:nickel cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006824">
        <property type="term" value="P:cobalt ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004688">
        <property type="entry name" value="Ni/Co_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011541">
        <property type="entry name" value="Ni/Co_transpt_high_affinity"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31611">
        <property type="entry name" value="PTHR31611"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03824">
        <property type="entry name" value="NicO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00802">
        <property type="entry name" value="nico"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0170">Cobalt</keyword>
    <keyword evidence="4" id="KW-0171">Cobalt transport</keyword>
    <keyword evidence="9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0533">Nickel</keyword>
    <keyword evidence="9" id="KW-0921">Nickel transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="78"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="123"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="186"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="219"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="259"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="306"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU362101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ41516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="342" mass="37738" checksum="12E33C4893509B40" modified="2010-01-19" version="1">MKISHTTQKHAIWLISSLIVVNVVVWITAIFAFYQRPGMLGMSLLAWSLGLRHAVDADHIAAIDTTTRKMMEQGKEPIAIGTFFSLGHSTIVMLAATAIAVTVGTFKDKIPYISNIGGTIGTSVSILFLLIMAYINLTIFISVYKKFNLYKKNQQIDKTELDIQLSGPLNKLFHFSFKFINKSWHMYFVGFLFGLGFDTATEITLLALSATNASQGMDIWLIMIFPILFTAGMSLIDTLDNLVMVGAYGWAFSKPSRKLYYNMTITGVSVIVALMIGGLEALSALASSLQLQGPIWDSINNMTDHFGMVGIAVVITFIACWLISIANYKIKGYDKLDAPLAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ36</accession>
    <name>D0YZ36_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002549</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300303.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41517">
        <property type="protein sequence ID" value="EEZ41517"/>
        <property type="gene ID" value="VDA_002549"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039536">
        <property type="entry name" value="TetR_C_Proteobacteria"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14246">
        <property type="entry name" value="TetR_C_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="6"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="201" mass="22559" checksum="0925388B11C37E9C" modified="2010-01-19" version="1">MRASTVEKKKRIIEVATELFIEHGYKDTSLDQIVAVCGGSKQTLYRYFGNKEGLLTEVMAYHTSVSLEEAFKLSDSQHLNVAEALEGFGLKYIKGLCADPLLSLFRIVAADFHKNQSVTESFWQRGPQRIHGYLIEYLQSDAVQQQLSITNPQLACAQLLALIKLDYQTTAMLGHELPDDNELKITITQAVAAFISLYKKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ97</accession>
    <name>D0YZ97_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Flagellar hook-associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002610</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300480.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002610"/>
    <dbReference type="EnsemblBacteria" id="EEZ41578">
        <property type="protein sequence ID" value="EEZ41578"/>
        <property type="gene ID" value="VDA_002610"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031Y76">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2078437at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0966">Cell projection</keyword>
    <keyword evidence="1" id="KW-0969">Cilium</keyword>
    <keyword evidence="1" id="KW-0282">Flagellum</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="62" mass="6796" checksum="244D4C4541A0A951" modified="2010-01-19" version="1">MNLLMTGLIGYALKEVVMPLITGEDNESDNSNQQVSDKEVDNALFESNDLVKLVSNIVDIVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZC0</accession>
    <name>D0YZC0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Sulfate transporter CysZ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">cysZ</name>
        <name evidence="9" type="ORF">VDA_002633</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell inner membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the CysZ family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300550.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002633"/>
    <dbReference type="EnsemblBacteria" id="EEZ41601">
        <property type="protein sequence ID" value="EEZ41601"/>
        <property type="gene ID" value="VDA_002633"/>
    </dbReference>
    <dbReference type="GeneID" id="57341111"/>
    <dbReference type="eggNOG" id="COG2981">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1972181at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015116">
        <property type="term" value="F:sulfate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019344">
        <property type="term" value="P:cysteine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000103">
        <property type="term" value="P:sulfate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00468">
        <property type="entry name" value="CysZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022985">
        <property type="entry name" value="Sulfate_CysZ"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2 8" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0198">Cysteine biosynthesis</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0764">Sulfate transport</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="145"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="209"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="252" mass="28879" checksum="91A8BDB686D8A840" modified="2010-01-19" version="1">MSTQPIKNTTSGAGYFMRGLSLVTQPGTRRFVIIPLLINIMLFGGAFGYVFSNLGEWIHHWLSYLPSWLDWLSYVLWPLMALATLVICSYFFSTIANWIAAPFNGLLAEYLEAKLTGQPAPDTGFSEVIKDLPRIMGREWIKLKYYLPKALGLLILMWIPAIGQTVGPILWFLFSAWMMTIQYADYPFDNHKVPFINMRDALKQKRGQSLSFGALIMLFTMTPIINLFVMPIAVCGATAMWVDNYRDQYRRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZK3</accession>
    <name>D0YZK3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Inositol-1-monophosphatase</fullName>
            <ecNumber evidence="6">3.1.3.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_002716</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>a myo-inositol phosphate + H2O = myo-inositol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:24056"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:84139"/>
            <dbReference type="EC" id="3.1.3.25"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the inositol monophosphatase superfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.25" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300799.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002716"/>
    <dbReference type="EnsemblBacteria" id="EEZ41684">
        <property type="protein sequence ID" value="EEZ41684"/>
        <property type="gene ID" value="VDA_002716"/>
    </dbReference>
    <dbReference type="GeneID" id="57341012"/>
    <dbReference type="eggNOG" id="COG0483">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1741160at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008934">
        <property type="term" value="F:inositol monophosphate 1-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052832">
        <property type="term" value="F:inositol monophosphate 3-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052833">
        <property type="term" value="F:inositol monophosphate 4-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046855">
        <property type="term" value="P:inositol phosphate dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031564">
        <property type="term" value="P:transcription antitermination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01639">
        <property type="entry name" value="IMPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033942">
        <property type="entry name" value="IMPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020583">
        <property type="entry name" value="Inositol_monoP_metal-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022337">
        <property type="entry name" value="Inositol_monophosphatase_SuhB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00377">
        <property type="entry name" value="IMPHPHTASES"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01959">
        <property type="entry name" value="SBIMPHPHTASE"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00629">
        <property type="entry name" value="IMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0889">Transcription antitermination</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="267" mass="28899" checksum="CF78098217747E8A" modified="2010-01-19" version="1">MHPMLNIAIRAARKAGDHVIKSLEKTQAITVAKKGNDVVTNIDLEAEAIIIETILKSYPDHCITSAESGVVKEGRDKDCQWIIDPIDGTRNFSRGYPHYAISVALRMRGRTEVAAVYDPSRNELFTATRGAGAQINSQRIRATEPRNLAETVVATGLPFAAKQHAESFQKIQGALFVECDDMRQSGCSALDLCYLAAARVDAVVKLGLKPWEITAGELIAREAGAICTDFTGNTNYLTSGNLVAGNARVVKSILAKIRENGSEALTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZX4</accession>
    <name>D0YZX4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dihydropteroate synthase</fullName>
            <shortName evidence="1">DHPS</shortName>
            <ecNumber evidence="1">2.5.1.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Dihydropteroate pyrophosphorylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002837</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 7,8-dihydrofolate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DHPS family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.15" evidence="1"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301155.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002837"/>
    <dbReference type="EnsemblBacteria" id="EEZ41805">
        <property type="protein sequence ID" value="EEZ41805"/>
        <property type="gene ID" value="VDA_002837"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0294">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1275854at2"/>
    <dbReference type="UniPathway" id="UPA00077">
        <property type="reaction ID" value="UER00156"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004156">
        <property type="term" value="F:dihydropteroate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00739">
        <property type="entry name" value="DHPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045031">
        <property type="entry name" value="DHP_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006390">
        <property type="entry name" value="DHP_synth_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011005">
        <property type="entry name" value="Dihydropteroate_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000489">
        <property type="entry name" value="Pterin-binding_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20941">
        <property type="entry name" value="PTHR20941"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00809">
        <property type="entry name" value="Pterin_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51717">
        <property type="entry name" value="SSF51717"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01496">
        <property type="entry name" value="DHPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00792">
        <property type="entry name" value="DHPS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50972">
        <property type="entry name" value="PTERIN_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pterin-binding" evidence="2">
        <location>
            <begin position="15"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU361205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="278" mass="30507" checksum="C86783AB9B9E1EDD" modified="2010-01-19" version="1">MILQSRSKILELTSPHVMGILNVTPDSFSDGGRFNHLDTALFHAEEMIDAGATFIDIGGESTRPGAADVSIDEELARVIPVVEAISNRFDCWISIDTSKAQVMTEAVKAGADLINDIRALREPGALEAAAKSEVPICLMHMQGQPRTMQTAPQYDDLLVDIEQFLLERINACEVVGISKQKLILDPGFGFGKTIKHNYQLLENLEKFHRFGLPILAGMSRKSMIYKLFENKRPEDCLAGSLACATIAAMKGAQIIRVHDVKETVEAVRICHETVSSGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZZ7</accession>
    <name>D0YZZ7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phosphoenolpyruvate--protein phosphotransferase</fullName>
            <ecNumber evidence="5">2.7.3.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">VDA_002860</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-histidyl-[protein] + phosphoenolpyruvate = N(pros)-phospho-L-histidyl-[protein] + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:23880"/>
            <dbReference type="Rhea" id="RHEA-COMP:9745"/>
            <dbReference type="Rhea" id="RHEA-COMP:9746"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:29979"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:64837"/>
            <dbReference type="EC" id="2.7.3.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PEP-utilizing enzyme family.</text>
    </comment>
    <dbReference type="EC" id="2.7.3.9" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301223.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002860"/>
    <dbReference type="EnsemblBacteria" id="EEZ41828">
        <property type="protein sequence ID" value="EEZ41828"/>
        <property type="gene ID" value="VDA_002860"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3605">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="467393at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008965">
        <property type="term" value="F:phosphoenolpyruvate-protein phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008279">
        <property type="entry name" value="PEP-util_enz_mobile_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018274">
        <property type="entry name" value="PEP_util_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000121">
        <property type="entry name" value="PEP_util_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023151">
        <property type="entry name" value="PEP_util_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036637">
        <property type="entry name" value="Phosphohistidine_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006318">
        <property type="entry name" value="PTS_EI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008731">
        <property type="entry name" value="PTS_EIN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036618">
        <property type="entry name" value="PtsI_HPr-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05524">
        <property type="entry name" value="PEP-utilisers_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00391">
        <property type="entry name" value="PEP-utilizers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02896">
        <property type="entry name" value="PEP-utilizers_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47831">
        <property type="entry name" value="SSF47831"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52009">
        <property type="entry name" value="SSF52009"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01417">
        <property type="entry name" value="PTS_I_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00742">
        <property type="entry name" value="PEP_ENZYMES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00370">
        <property type="entry name" value="PEP_ENZYMES_PHOS_SITE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0598">Phosphotransferase system</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="13" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="GAF" evidence="12">
        <location>
            <begin position="17"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="209"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ41828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="752" mass="84106" checksum="F5FFCBC0F248A542" modified="2010-01-19" version="1">MLAQLREIVEKVVSASNLIDALDQLVIQTCLALDAECCSIYIADHGRREYTLMATKGLHKQSAHVALKFDEGLVGLVGRKAEPVNVADAHNHPEFKHLPDIGEERFASFFGTPIIHQRQVLGVLVIQQRCCRVFDESEESFMVTLAAQIATILAHAKAQGMWPRQRQGMHYTGVVASTGIAVAKAWWDDTQPQLESVQPAFAADIIQEQERLSIAIDKASAEFRRLRKRFDNELQKETLAIFDLFNHLLNDPMLRKDLFAKINAGDLAEWAVRQVVEDYSARFAQMRDEYLKERAQDLRELGQRLLYFLSHDEVVEQKWDEPIVLLTRELTAAMLASIPTDKLAAVVAQEGAANSHAAILSRTLGVPAIMGVDFVPESAHNKRVIVDGYRGEFTVQPNRLVLKEYRRLLKEEQELTQIVSEELARPAITSDGCKVQTYLNTGLNSETCQNLKAGIDGVGLYRTEVPFLLQHSFPSEDEQRSQYHTMLTTYAPMPVVMRTLDIGGDKPLPYLPIEEDNPFLGWRGIRFTLDHPEIFTIQVRAMLQASIGLNNLDILLPMISSVGEIEEAKELIDKAYQDVLLQAQGRGLSLSYPRIGIMIEVPSMLYQLDALQGRVDFISVGSNDLTQYLLAVDRNNARVASVYDPLHPAVLHALHHIVQSSNRLQIPVSLCGELAGDPLGAVLLVGMGYRSLSMNTRSMAKIKYMLKHLTIADMESLAQSVLSVYFAQDVRAQTVQFLEHHGLGGLVRAGKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0A0</accession>
    <name>D0Z0A0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">3-isopropylmalate dehydrogenase</fullName>
            <ecNumber evidence="13">1.1.1.85</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">3-IPM-DH</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Beta-IPM dehydrogenase</fullName>
            <shortName evidence="13">IMDH</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">leuB</name>
        <name evidence="16" type="ORF">VDA_002963</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13 14">Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13 14">
            <text>(2R,3S)-3-isopropylmalate + NAD(+) = 4-methyl-2-oxopentanoate + CO2 + NADH</text>
            <dbReference type="Rhea" id="RHEA:32271"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17865"/>
            <dbReference type="ChEBI" id="CHEBI:35121"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.85"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13 14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="13 14">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="13 14">Binds 1 Mg(2+) or Mn(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 13 14">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 3/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 13 14">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.85" evidence="13"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301430.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002963"/>
    <dbReference type="EnsemblBacteria" id="EEZ41931">
        <property type="protein sequence ID" value="EEZ41931"/>
        <property type="gene ID" value="VDA_002963"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0473">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1551125at2"/>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00072"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003862">
        <property type="term" value="F:3-isopropylmalate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01033">
        <property type="entry name" value="LeuB_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019818">
        <property type="entry name" value="IsoCit/isopropylmalate_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004429">
        <property type="entry name" value="Isopropylmalate_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42979">
        <property type="entry name" value="PTHR42979"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00169">
        <property type="entry name" value="leuB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00470">
        <property type="entry name" value="IDH_IMDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="12 13 14" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 13 14" id="KW-0432">Leucine biosynthesis</keyword>
    <keyword evidence="9 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13" id="KW-0464">Manganese</keyword>
    <keyword evidence="8 13 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 13 14" id="KW-0520">NAD</keyword>
    <keyword evidence="10 13 16" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Iso_dh" evidence="15">
        <location>
            <begin position="6"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="78"/>
            <end position="91"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="227"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="251"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="255"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="285"/>
            <end position="297"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalysis" evidence="13">
        <location>
            <position position="145"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalysis" evidence="13">
        <location>
            <position position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU004445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EEZ41931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="363" mass="39522" checksum="D7142151BDFFDB10" modified="2010-01-19" version="1">MAPQYRIAVLPGDGIGPEVMEQALKVLAAIQQRFGFTLSCEQYDVGGVAIDHHGTPLPESTLTGCQNADAILFGSVGGPKWEHLPPNEQPERGALLPLRKHFELFCNLRPAQIHSGLEALSPLRADISAQGFDIVVVRELTGGIYFGQPKGREGEGAMEKAFDTEIYHRYEIERIARIAFESANLRQQKVCSIDKANVLQSSILWRQVVEEVHKDYPHIELSHMYIDNATMQLIKNPAQFDVMLCSNIFGDILSDECAMITGSMGMLPSASLNQKQFGLYEPAGGSAPDIAGKNIANPVAQILSAALMLRYSLGEEEAARAIECAVAQALEAGEVTADLAREQSALSTNEMGDRIAHYVSAQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0J6</accession>
    <name>D0Z0J6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Co-chaperonin GroES</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">10 kDa chaperonin</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Chaperonin-10</fullName>
            <shortName evidence="3">Cpn10</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">groES</name>
        <name evidence="3" type="synonym">groS</name>
        <name evidence="5" type="ORF">VDA_003060</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 4">Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 4">Belongs to the GroES chaperonin family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301722.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003060"/>
    <dbReference type="EnsemblBacteria" id="EEZ42027">
        <property type="protein sequence ID" value="EEZ42027"/>
        <property type="gene ID" value="VDA_003060"/>
    </dbReference>
    <dbReference type="GeneID" id="57340470"/>
    <dbReference type="eggNOG" id="COG0234">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1965002at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00320">
        <property type="entry name" value="cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.33.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00580">
        <property type="entry name" value="CH10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020818">
        <property type="entry name" value="Chaperonin_GroES"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037124">
        <property type="entry name" value="Chaperonin_GroES_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018369">
        <property type="entry name" value="Chaprnonin_Cpn10_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10772">
        <property type="entry name" value="PTHR10772"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00166">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00297">
        <property type="entry name" value="CHAPERONIN10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00883">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00681">
        <property type="entry name" value="CHAPERONINS_CPN10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0346">Stress response</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ42027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="96" mass="10310" checksum="5045153DF63B498A" modified="2010-01-19" version="1">MNIRPLHDRVIVERKEVESKSAGGIVLTGSAAEKSTRGTVLAVGNGRILENGSVQPLDVKVGDTVIFAEGYNTKTEKIDGKEVLIMSENDIMAIVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0K1</accession>
    <name>D0Z0K1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_003065</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301735.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003065"/>
    <dbReference type="EnsemblBacteria" id="EEZ42032">
        <property type="protein sequence ID" value="EEZ42032"/>
        <property type="gene ID" value="VDA_003065"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="6"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="143"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ42032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="209" mass="22920" checksum="ABBED849C6BE21B8" modified="2010-01-19" version="1">MDAQYTIIIADDHPLFRSALLQSVHLAIGGVTLLEADSLSSLQRLLEKHHLDVDLLLLDLKMPGANGMSGLIELRQCYPDLPIVVVSASEEPAIIKQVYRHGAFGFIPKSSGMKALHGALNQVLAGDNYFPTDIDALDETDELVEKIATLTPQQLKVLKMLADGLLNKQIAYELDVSEATIKAHMTAIFRKLSVTNRTQAVILLQNIVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0U7</accession>
    <name>D0Z0U7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Uroporphyrinogen-III synthase</fullName>
            <ecNumber evidence="1">4.2.1.75</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_003161</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>hydroxymethylbilane = H2O + uroporphyrinogen III</text>
            <dbReference type="Rhea" id="RHEA:18965"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57308"/>
            <dbReference type="ChEBI" id="CHEBI:57845"/>
            <dbReference type="EC" id="4.2.1.75"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 3/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the uroporphyrinogen-III synthase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.75" evidence="1"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302043.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003161"/>
    <dbReference type="EnsemblBacteria" id="EEZ42128">
        <property type="protein sequence ID" value="EEZ42128"/>
        <property type="gene ID" value="VDA_003161"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1587">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1185397at2"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00320"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004852">
        <property type="term" value="F:uroporphyrinogen-III synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006780">
        <property type="term" value="P:uroporphyrinogen III biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06578">
        <property type="entry name" value="HemD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10090">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036108">
        <property type="entry name" value="4pyrrol_syn_uPrphyn_synt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003754">
        <property type="entry name" value="4pyrrol_synth_uPrphyn_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039793">
        <property type="entry name" value="UROS/Hem4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38042">
        <property type="entry name" value="PTHR38042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02602">
        <property type="entry name" value="HEM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69618">
        <property type="entry name" value="SSF69618"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="1" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HEM4" evidence="2">
        <location>
            <begin position="14"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU366031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ42128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="251" mass="27932" checksum="BDE3AA2BBCA50837" modified="2010-01-19" version="1">MTILVTRPSPDGEQLAHQLCAVGLTVIHQPLLAITSGDEVDLLISQLNWLKSDDFLIAVSDHAVKLAHNYLQSQGASWPKNVHYMAVGHKTAATLAKVTGQSVLMPQHRCDSEGLLALPELQQIRHRRVLILRGNGGRELIRQELIARHAEVHYCETYQRCWLPLDGTTLADSWQQQQVDKLVVTSGEQLAFLHQLVPQHNHAWFLNCHLFVPSQRIADQASQLGFTHISTVGSASNQALFTFLSNMSTMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0X5</accession>
    <name>D0Z0X5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Peptide ABC transporter permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_003189</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302113.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003189"/>
    <dbReference type="EnsemblBacteria" id="EEZ42156">
        <property type="protein sequence ID" value="EEZ42156"/>
        <property type="gene ID" value="VDA_003189"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0601">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1479518at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045621">
        <property type="entry name" value="BPD_transp_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19300">
        <property type="entry name" value="BPD_transp_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="9"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="100"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="133"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="188"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="243"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="289"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="94"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ42156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="325" mass="35594" checksum="930823E72EC7AE36" modified="2010-01-19" version="1">MFTFLVKRLFQALIVMFVISLVAFAIQDNLGDPLRELVGQSVSEAERQELRNELGLNDPFVTKYGRFLTNAVQGDLGTSYTFKRPAAEVILDKLVATLELVFGATVLIVVISIPLGVYSAIHPHSTATKAIMAFSSIGISIPVFLTAIMLMYVFSIELGWLPSFGRGETTNVFGWESGYFTLDGLKHLVLPCVALASIMLPLFIRLVRSEMLEVLSSEYVKFAKAKGLPLQAIYYQHALKNTMLPVLTVGGVQIGTMIAYTILTESVFQWPGTGLLFLDAINRVDTPLITAYVIFVGLIFVVTNTVVDLLYGLVNPTVNLTGKGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z147</accession>
    <name>D0Z147_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Trk system potassium uptake protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">VDA_003261</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell inner membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the TrkH potassium transport family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302321.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003261"/>
    <dbReference type="EnsemblBacteria" id="EEZ42228">
        <property type="protein sequence ID" value="EEZ42228"/>
        <property type="gene ID" value="VDA_003261"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0168">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="756220at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015379">
        <property type="term" value="F:potassium:chloride symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003445">
        <property type="entry name" value="Cat_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004772">
        <property type="entry name" value="TrkH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02386">
        <property type="entry name" value="TrkH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006247">
        <property type="entry name" value="TrkH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00933">
        <property type="entry name" value="2a38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 10" id="KW-0630">Potassium</keyword>
    <keyword evidence="4 9" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="69"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="136"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="184"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="238"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="276"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="333"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="398"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="458"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="221"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="320"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="321"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="437"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="438"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR006247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR006247-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ42228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="485" mass="53226" checksum="A19462FCE1319F70" modified="2010-01-19" version="1">MQFRSIIRIVGLLLAFFSVTMLAPALVALIYRDGAGVPFIVTFFLLFAGGAALWFPNRRHRHELKAREGFLIVVLFWVVIGSAGAVPFILSHTPDLSVTDSFFESFSALTTTGATVIVGLDALPKAILFYRQFLQWFGGMGIIVLAVAVLPVLGIGGMQLYRAEIPGPVKDSKMTPRIAETAKTLWFIYLALTVSCALAFWVAGMTPFDAIAHSFSTIAIGGFSTHDASMGYFNSPTINMITMVFLLISACNFSLHFAAFANGGIRLRTYWRDPEFRAFLFIQLMLFVICFAILVNHHSYDSYYQAMDQALFQTVSISTTAGFTTTGFADWPLFLPVLLLFSSFIGGCAGSTGGGMKVIRMLLLSLQGVRELKRLIHPRAVYTIKLGKKALPQRVVDAVWGFFSAYALVFVVCMLALIATGLDELTSFSAVAATLNNLGPGLGEVAVHFGEINDPAKWILVVAMLFGRLEVFTLLVLFTPTFWRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z159</accession>
    <name>D0Z159_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sulfur carrier protein adenylyltransferase ThiF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_003273</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302353.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003273"/>
    <dbReference type="EnsemblBacteria" id="EEZ42240">
        <property type="protein sequence ID" value="EEZ42240"/>
        <property type="gene ID" value="VDA_003273"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0476">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1408716at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008641">
        <property type="term" value="F:ubiquitin-like modifier activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="PTHR10953"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="SSF69572"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="ThiF" evidence="2">
        <location>
            <begin position="13"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ42240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="261" mass="28279" checksum="34A6D1930C865332" modified="2010-01-19" version="1">MTPSLTDHQFLRYSRQLMVPEISEQGQSQLAQAKVLFIGAGGLGSIAALYLAGAGIGALWLADGDKVELSNLARQILYRESDLGRNKAVQASTQLSQLNPTVSIVPLTSHLHDNGLVDAISRVDLVLDCSDNFTTRYAVNKACMECQIPLISGAAIGWQGQVISFGFHQSSSPCYHCLYPQMAKTQTKQNCQTMGVVGPLVGVIGAFQALEAIKYFTVPQSITWGELHQFNGLNNQWQSVQCGSDVSCLVCQQENENEAVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z178</accession>
    <name>D0Z178_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Hydrolase (HAD superfamily)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_003292</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003292"/>
    <dbReference type="EnsemblBacteria" id="EEZ42259">
        <property type="protein sequence ID" value="EEZ42259"/>
        <property type="gene ID" value="VDA_003292"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0561">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006379">
        <property type="entry name" value="HAD-SF_hydro_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01484">
        <property type="entry name" value="HAD-SF-IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ42259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="204" mass="22547" checksum="1C628577C720D781" modified="2010-01-19" version="1">MITSNGARVHNGDGEEIFSQDLSPEVIKGVIDIVKDDPEVLIHMYRGNDWLLNCEDDTLREFHESFSYIVFDVNNPPTEHVAKVFFTRNDHSHEKMMVWEERLNQAFGDKANIAFSTPWCLEVMAAGVSKGHALEAVAKQQGLTLADCIAFGDGMNDAEMLAMAGKGLIMGTAHEKVKQALPNNEVIGSCADEAVAHYLIDNLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z192</accession>
    <name>D0Z192_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RNA polymerase sigma factor RpoH</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">RNA polymerase sigma-32 factor</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rpoH</name>
        <name evidence="9" type="ORF">VDA_003306</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Interacts with the RNA polymerase core enzyme.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the sigma-70 factor family. RpoH subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302451.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003306"/>
    <dbReference type="EnsemblBacteria" id="EEZ42273">
        <property type="protein sequence ID" value="EEZ42273"/>
        <property type="gene ID" value="VDA_003306"/>
    </dbReference>
    <dbReference type="GeneID" id="57340254"/>
    <dbReference type="eggNOG" id="COG0568">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1565734at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00961">
        <property type="entry name" value="Sigma70_RpoH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000943">
        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009042">
        <property type="entry name" value="RNA_pol_sigma70_r1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012759">
        <property type="entry name" value="RNA_pol_sigma_RpoH_proteobac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00140">
        <property type="entry name" value="Sigma70_r1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000770">
        <property type="entry name" value="RNA_pol_sigma-SigE/K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00046">
        <property type="entry name" value="SIGMA70FCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02392">
        <property type="entry name" value="rpoH_proteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00715">
        <property type="entry name" value="SIGMA70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00716">
        <property type="entry name" value="SIGMA70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="2 6" id="KW-0346">Stress response</keyword>
    <keyword evidence="5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="1 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RNA_pol_sigma70" evidence="7">
        <location>
            <begin position="77"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_sigma70" evidence="8">
        <location>
            <begin position="252"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="6">
        <location>
            <begin position="253"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Sigma-70 factor domain-2" evidence="6">
        <location>
            <begin position="53"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Interaction with polymerase core subunit RpoC" evidence="6">
        <location>
            <begin position="77"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ42273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="287" mass="32844" checksum="92FC2726733FBECA" modified="2010-01-19" version="1">MSTEMPSMALVAADSLDSYIQAVNRYPMLTAEQEKELAERLHFDGDIDAAKALVMSHLRFVVHIARGYSGYGLPMADLIQEGNIGLMKAVKRFNPEVGVRLVSFAVHWIKAEIHEFVLRNWRIVKVATTKAQRKLFFNLRKSKKRLGWFNNEEINMVADQLGVEPSEVREMESRLAAQDATFEMSNDDDDRDFTPTAPAYYLEDKSSDVARSYEESNWETHATNRLSQALAGLDERSQFIVRSRWLDEDKSTLQDLADRFGVSAERIRQLEKNAMKKLKEAVGDDIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1H4</accession>
    <name>D0Z1H4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional (Co)regulator CytR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_003388</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302623.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003388"/>
    <dbReference type="EnsemblBacteria" id="EEZ42355">
        <property type="protein sequence ID" value="EEZ42355"/>
        <property type="gene ID" value="VDA_003388"/>
    </dbReference>
    <dbReference type="GeneID" id="57340162"/>
    <dbReference type="eggNOG" id="COG1609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="664909at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="2"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ42355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="334" mass="36493" checksum="2CDC245B70C1A873" modified="2010-01-19" version="1">MATMKDVAQLAGVSTATVSRALMNPEKVSASTRKKVEQAVMEAGYSPNSLARNLRRNESKTIVTIVPDICDPYFTEIIRGIEEAAMEHGYLVLLGDSGQQKTRENSFVNLVFTKQADGMLLLGTDLPFDVSKPEQKNLPPLVMACEYAPELELPTVHIDNLTAAFEAVNYLTQMGHRRIAQISGPSKAALSEFRAQGYQQALRRGGIELNPAYTITGDFSFAAGARAVTNLLSLPEPPTAIFCHSDVMAIGAMQQAKRLGLRVPQDISIVGFDDIQFAEFCDPPLTTVSQPRYEIGRQAMLMLLELLKGKEVQAGSRLLDAKLVIRESAAPPLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1I0</accession>
    <name>D0Z1I0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003394</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003394"/>
    <dbReference type="EnsemblBacteria" id="EEZ42361">
        <property type="protein sequence ID" value="EEZ42361"/>
        <property type="gene ID" value="VDA_003394"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1695">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018309">
        <property type="entry name" value="Tscrpt_reg_PadR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10400">
        <property type="entry name" value="Vir_act_alpha_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Vir_act_alpha_C" evidence="1">
        <location>
            <begin position="46"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="142" mass="16497" checksum="D8E35828E9FD2927" modified="2010-01-19" version="1">MATNDLVTCRLEPQEGKPDRKVYSITDLGRQALFAWFQEPAQNPTTRDEFSAKLLVCGVHNSEPMQQQLEALIEESRALINHYHELEKVHFPNHRSLDRQTRLERLTLRRGIHNRQAWIYWAEEVLAELKDMDSSSSAVAIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1I1</accession>
    <name>D0Z1I1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 10">Phosphoenolpyruvate carboxylase</fullName>
            <shortName evidence="10">PEPC</shortName>
            <shortName evidence="10">PEPCase</shortName>
            <ecNumber evidence="5 10">4.1.1.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ppc</name>
        <name evidence="13" type="ORF">VDA_003395</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 10">Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>oxaloacetate + phosphate = hydrogencarbonate + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:28370"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="4.1.1.31"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the PEPCase type 1 family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.31" evidence="5 10"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302636.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003395"/>
    <dbReference type="EnsemblBacteria" id="EEZ42362">
        <property type="protein sequence ID" value="EEZ42362"/>
        <property type="gene ID" value="VDA_003395"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2352">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="398146at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008964">
        <property type="term" value="F:phosphoenolpyruvate carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015977">
        <property type="term" value="P:carbon fixation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006107">
        <property type="term" value="P:oxaloacetate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00595">
        <property type="entry name" value="PEPcase_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021135">
        <property type="entry name" value="PEP_COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022805">
        <property type="entry name" value="PEP_COase_bac/pln-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018129">
        <property type="entry name" value="PEP_COase_Lys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033129">
        <property type="entry name" value="PEPCASE_His_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30523">
        <property type="entry name" value="PTHR30523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00311">
        <property type="entry name" value="PEPcase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00150">
        <property type="entry name" value="PEPCARBXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00781">
        <property type="entry name" value="PEPCASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00393">
        <property type="entry name" value="PEPCASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0120">Carbon dioxide fixation</keyword>
    <keyword evidence="8 10 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="10 11">
        <location>
            <position position="138"/>
        </location>
    </feature>
    <feature type="active site" evidence="10 12">
        <location>
            <position position="543"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ42362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="876" mass="98450" checksum="C63D0A5C37CBCEB4" modified="2010-01-19" version="1">MNEKYSALKSNVSMLGHLLGNTIKDAHGEELLNKVETIRKLSKSARAGNSDDRAKLINELQNLPDDELLPVARAFSQFLNLTNIAEQYHTVSRHCETSVCSPDSIDGLFTQLEQGDINQFDTINAIRNLKIDLVLTAHPTEIARRTMIHKLVQINKCLSKLELSELSSAERQRIETRLEQLIAQAWHSDVIRQQRPTPLDEAKWGFAVVENSLWQAVPDFLRQFDDKLEAHIGEGLPIDAAPVTFSSWMGGDRDGNPFVTSQVTREVLLLSRWKAADLYLKDIQELVSELSMVKCNDQVRALAGDEHEPYRAILKNLRSQLTHTRDILDAQIKGQSVALLPIISDESQLWDPLYACYQSLHECGMGIIADGLLLDTLRRIKCFGIHLVRLDIRQESTRHSDVISELTRYLGLGDYDQWSEQDKVAFLVRELSSKRPLLPRHWQPSPEVQEVIDTCKTIAKQPKDALGAYVISMARTASDVLAVHLLLQEAGCPFRMDVCPLFETLDDLNNGADVIEQLLNIDWYRGFIQNHQMVMIGYSDSAKDAGVMSAGWAQYHAMEKLVDVCEKAGVELTLFHGRGGTIGRGGAPAHAALLSQPPRSLKGGLRVTEQGEMIRFKLGLPEVAVNSLSLYASATLQANLLPPPAPKQEWCELMDSLSEVSCKAYRDVVRGNPEFVPYFRAATPELELGKLPLGSRPAKRNPTGGVESLRAIPWIFAWSQNRLLLPAWLGAGEAIQNSIDQGHTELLEEMCREWPFFSTRLGMLEMVFTKTNVGIAQYYDQRLTDEALWPLGQKLRDQLQQDIKTVLTVENNDHLMEQDPWGAEAIRLRNIYVEPLNMLQAELLYRNRQQQESSPMMEEALMVTIAGIATGMRNTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1M8</accession>
    <name>D0Z1M8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rplB</name>
        <name evidence="7" type="ORF">VDA_003442</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL2 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302789.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003442"/>
    <dbReference type="EnsemblBacteria" id="EEZ42409">
        <property type="protein sequence ID" value="EEZ42409"/>
        <property type="gene ID" value="VDA_003442"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0090">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="961486at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01320_B">
        <property type="entry name" value="Ribosomal_L2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022666">
        <property type="entry name" value="Rbsml_prot_L2_RNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002171">
        <property type="entry name" value="Ribosomal_L2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005880">
        <property type="entry name" value="Ribosomal_L2_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022669">
        <property type="entry name" value="Ribosomal_L2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022671">
        <property type="entry name" value="Ribosomal_L2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014726">
        <property type="entry name" value="Ribosomal_L2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13691">
        <property type="entry name" value="PTHR13691"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00181">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03947">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002158">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01383">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01382">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01171">
        <property type="entry name" value="rplB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00467">
        <property type="entry name" value="RIBOSOMAL_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L2_C" evidence="6">
        <location>
            <begin position="124"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="223"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ42409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="274" mass="30136" checksum="BBA219477C70F83F" modified="2010-01-19" version="1">MAIVKCKPTSPGRRHVVKVVNSDLHKGKPYAPLLEKNSKTGGRNNNGRITVRHIGGGNKQHYRLIDFKRTKDGIPAKVERLEYDPNRSANIALVLYKDGERRYIIAPKGLQAGDMIQSGEDAAIKVGNTLPMRNIPVGSTVHCVELKPGKGAQIARSAGAYAQIIARAGTYVTLRLRSGEMRKVLADCRATLGEVGNHEHMLRELGKAGASRWRGVRPTVRGVVMNPVDHPHGGGEGRTSGGRHPVTPWGVPTKGYKTRKNKRTDKYIVRRRNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1Q8</accession>
    <name>D0Z1Q8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_003472</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303543.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003472"/>
    <dbReference type="EnsemblBacteria" id="EEZ42439">
        <property type="protein sequence ID" value="EEZ42439"/>
        <property type="gene ID" value="VDA_003472"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="635734at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="13"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="179"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ42439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="356" mass="40172" checksum="1BC652FECB0636A3" modified="2010-01-19" version="1">MNGAQIVQHLQPGGIERLVLNLLRFSSSRFNLKVIALEGHRDQALQHWPELRQFQNRLIFLNKPSGFKPHIFFQLKGILKQHQVHFIHSHHLGPLFYSRPISQFMGLQHVHTEHDSWHLENPKARKQTQLLATGKHLSLIADANHIAKDLQRYLKRNVDHVILNGIDSQIFTLGDPIKARAQLRLPPDCFLIGAAGRLVAEKGMGLLLQALAQLPLHYHIAIAGIGPQQSILKQQAKQLGIQSRVHWLNLVDDMPLFYQAIDLFCLPSTNEGLPLSLLEAQSCGKWVVATDVGAVREVITSYSGHIIADRSVKALTDAILNAPLQPSDPMIREHIIKNTDVRIMVEQYEKIWSSAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1V7</accession>
    <name>D0Z1V7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Arabinose 5-phosphate isomerase</fullName>
            <shortName evidence="2">API</shortName>
            <ecNumber evidence="2">5.3.1.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_003521</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>D-arabinose 5-phosphate = D-ribulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:23104"/>
            <dbReference type="ChEBI" id="CHEBI:57693"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="EC" id="5.3.1.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the SIS family. GutQ/KpsF subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.13" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303683.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003521"/>
    <dbReference type="EnsemblBacteria" id="EEZ42488">
        <property type="protein sequence ID" value="EEZ42488"/>
        <property type="gene ID" value="VDA_003521"/>
    </dbReference>
    <dbReference type="GeneID" id="57340004"/>
    <dbReference type="eggNOG" id="COG0517">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0794">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="571638at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019146">
        <property type="term" value="F:arabinose-5-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901135">
        <property type="term" value="P:carbohydrate derivative metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05014">
        <property type="entry name" value="SIS_Kpsf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004800">
        <property type="entry name" value="KdsD/KpsF-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035474">
        <property type="entry name" value="SIS_Kpsf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01380">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004692">
        <property type="entry name" value="KdsD_KpsF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00393">
        <property type="entry name" value="kpsF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0129">CBS domain</keyword>
    <keyword evidence="2 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="SIS" evidence="7">
        <location>
            <begin position="35"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="6">
        <location>
            <begin position="204"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="6">
        <location>
            <begin position="271"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="site" description="Catalytically relevant" evidence="4">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <feature type="site" description="Catalytically relevant" evidence="4">
        <location>
            <position position="105"/>
        </location>
    </feature>
    <feature type="site" description="Catalytically relevant" evidence="4">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <feature type="site" description="Catalytically relevant" evidence="4">
        <location>
            <position position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR004692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR004692-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR004692-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ42488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="322" mass="34350" checksum="54CD1C996163D415" modified="2010-01-19" version="1">MPKFDFCANGLRVIETEIHALNNIRQYINQDFANACELILNCSGKVIVMGMGKSGHIGNKIAATLASTGTSAFFVHPGEASHGDLGMIKKNDVVIAISNSGEASEILALLPVIKRLGIPLIAMTGKPESSMAKLAQYHLQITVDKEACPLNLAPTSSTTATLVMGDALAIAIMEARGFTANDFALSHPGGALGRKLLMRISDVMHSGDDLPIVTEHATIKDALLEISRKGLGMTAIVDNEQQLIGIFTDGDLRRLLDDHIDIHNTTIGTVMSRNPKTISPQLLAAEGLKLMEDKKINGLLVTEQSCLVGALNMHDLLKAGVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1W5</accession>
    <name>D0Z1W5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Periplasmic serine endoprotease DegP-like</fullName>
            <ecNumber evidence="4">3.4.21.107</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_003529</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>Acts on substrates that are at least partially unfolded. The cleavage site P1 residue is normally between a pair of hydrophobic residues, such as Val-|-Val.</text>
            <dbReference type="EC" id="3.4.21.107"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase S1C family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.107" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003529"/>
    <dbReference type="EnsemblBacteria" id="EEZ42496">
        <property type="protein sequence ID" value="EEZ42496"/>
        <property type="gene ID" value="VDA_003529"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0265">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011782">
        <property type="entry name" value="Pept_S1C_Do"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001940">
        <property type="entry name" value="Peptidase_S1C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00595">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00834">
        <property type="entry name" value="PROTEASES2C"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02037">
        <property type="entry name" value="degP_htrA_DO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0720">Serine protease</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="PDZ" evidence="5">
        <location>
            <begin position="216"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="5">
        <location>
            <begin position="313"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="3">
        <location>
            <position position="67"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="3">
        <location>
            <position position="97"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="3">
        <location>
            <position position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR611782-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ42496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="413" mass="43839" checksum="FF65E21056837BBB" modified="2010-01-19" version="1">MLEQVTPAVVSIAVEGKHVSKQRLPEAYRFFFGPDFPTEQVREQPFRGLGSGVIIDAKKGYVVTNNHVVDGADTIKVQLSDGREVKAKLLGTDKMSDIALLQLEDAKDLTAIKLADSDNLRVGDFAVAIGNPFGLGQTVTSGIVSALGRSGLNIENFENFIQTDAPINSGNSGGALVNLNGELIGINTAILGPNGGNVGIGFAIPANMVKNLTDQLIEFGQVKRGVLGVTGGELTSELAETFGYKTNHGAFVSQVLPEGSAAKAGLKAGDIIVSVNNKPIRTFSELRAKIATLGAGKKVTLGLIRDGKELNVPVTLEAAKQTQVKADDLHESLAGAEFANTSPEDKVHGVKVTELNKQSIAARYGLKKGDIIIGLNRQPIKNLGELRKALEKKPNVLAMEVKRGDSVLYLIMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z290</accession>
    <name>D0Z290_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Predicted membrane-associated metal-dependent hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_000541</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304673.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000541"/>
    <dbReference type="EnsemblBacteria" id="EEZ39521">
        <property type="protein sequence ID" value="EEZ39521"/>
        <property type="gene ID" value="VDA_000541"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2194">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1067869at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008484">
        <property type="term" value="F:sulfuric ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016772">
        <property type="term" value="F:transferase activity, transferring phosphorus-containing groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012549">
        <property type="entry name" value="EptA-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040423">
        <property type="entry name" value="PEA_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30443">
        <property type="entry name" value="PTHR30443"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08019">
        <property type="entry name" value="EptA_B_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="120"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="154"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="EptA_B_N" evidence="9">
        <location>
            <begin position="59"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="8">
        <location>
            <begin position="239"/>
            <end position="528"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ39521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="546" mass="61988" checksum="3D275DEF51AE21E6" modified="2010-01-19" version="1">MKNLLTHIKQPKTVGMVTFLLALYFAIVLNLPLWRTFEHIFQTLPAVKIGFIISLPIFLTAALNIIFNLFSWPYITKPFFSILIFFSALVCYAMYQYGAIFDYGMMENIFETNAGEATSYFSLTGVVWVTVLGVLPVILLLKTPIKPYSSALKFVLMKLVSILASLVIIGLVAFFYYKDYSSVGRNNHYLNRVINPAYVYALGKYVDKTYFTEPMKYQEIGTDAKQVVSKTHNGKPTLFVFVLGETARSMNYELNGYPRPTNQYTKKDGVISFKSVSSCGTATAVSVPCMFSAMNKSDYNRERAYNQDTFIDILHRAGISMLWKENDGGDKGAADRINKIVLDRSSDNPLCDGESCYDMALLNNFDKEVSDMKGNKFIALHIMGSHGPTYYKRYPKDHAFFKPDCQRADIENCTTQEIVNSYDNTILYTDYVIDQLIQKLKGYSKEYNTALFYISDHGESLGEDGLYLHGTPYALAPKYQTTVPMMVWMSKGFEQDRGINPSCLEKEAESGHFSQDNVFHSMLGVMDVQTKVYNPKLDIFKTCRSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z292</accession>
    <name>D0Z292_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N-acetylmuramic acid 6-phosphate etherase</fullName>
            <shortName evidence="3">MurNAc-6-P etherase</shortName>
            <ecNumber evidence="3">4.2.1.126</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">N-acetylmuramic acid 6-phosphate hydrolase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">N-acetylmuramic acid 6-phosphate lyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">murQ</name>
        <name evidence="5" type="ORF">VDA_000543</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>H2O + N-acetyl-D-muramate 6-phosphate = (R)-lactate + N-acetyl-D-glucosamine 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:26410"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16004"/>
            <dbReference type="ChEBI" id="CHEBI:57513"/>
            <dbReference type="ChEBI" id="CHEBI:58722"/>
            <dbReference type="EC" id="4.2.1.126"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-sugar metabolism; 1,6-anhydro-N-acetylmuramate degradation.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-sugar metabolism; N-acetylmuramate degradation.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cell wall biogenesis; peptidoglycan recycling.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="3">A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.126" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304677.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000543"/>
    <dbReference type="EnsemblBacteria" id="EEZ39523">
        <property type="protein sequence ID" value="EEZ39523"/>
        <property type="gene ID" value="VDA_000543"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2103">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1100044at2"/>
    <dbReference type="UniPathway" id="UPA00342"/>
    <dbReference type="UniPathway" id="UPA00343"/>
    <dbReference type="UniPathway" id="UPA00544"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016835">
        <property type="term" value="F:carbon-oxygen lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097175">
        <property type="term" value="P:1,6-anhydro-N-acetyl-beta-muramic acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046348">
        <property type="term" value="P:amino sugar catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097173">
        <property type="term" value="P:N-acetylmuramic acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009254">
        <property type="term" value="P:peptidoglycan turnover"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd05007">
        <property type="entry name" value="SIS_Etherase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00068">
        <property type="entry name" value="MurQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005488">
        <property type="entry name" value="Etherase_MurQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005486">
        <property type="entry name" value="Glucokinase_regulatory_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040190">
        <property type="entry name" value="MURQ/GCKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10088">
        <property type="entry name" value="PTHR10088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10088:SF5">
        <property type="entry name" value="PTHR10088:SF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13580">
        <property type="entry name" value="SIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00274">
        <property type="entry name" value="TIGR00274"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01272">
        <property type="entry name" value="GCKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="1 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SIS" evidence="4">
        <location>
            <begin position="57"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="85"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="298" mass="31304" checksum="41DB531F06018132" modified="2010-01-19" version="1">MKIDLSQLVTESRNQASHAIDTLSTLDMVTVINQEDQKVALAVEKTLPEVALAVDAIADAFMVGGRLIYMGAGTSGRLGILDASECPPTYGSNPNQVVGLIAGGHKAILKAVENAEDNQELAKQDLQNLGLTENDVVVGIAASGRTPYVIGGMKYAHSIGAQVVAISCNPQSEMTKIADIAITPVVGAEVVTGSSRMKAGTAQKFVLNMLTTGAMIRTGKVFGNLMVDVEATNAKLIQRQTNIVMQATDCDVAQAEEALSACDRHCKTAILMILAGLDAEQAKKQLANHNGFIRSALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z299</accession>
    <name>D0Z299_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_000550</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304695.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000550"/>
    <dbReference type="EnsemblBacteria" id="EEZ39530">
        <property type="protein sequence ID" value="EEZ39530"/>
        <property type="gene ID" value="VDA_000550"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1108236at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="82"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="110"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="168"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="199"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="231"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="284"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="317"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="347"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="372"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="418"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="504"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="13"/>
            <end position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="545" mass="57347" checksum="AC4FDA3F8D17F894" modified="2010-01-19" version="1">MNQQVNNSNKWLTLLILCAAQVGTSGDNATVGVSASSLTKLFGASMDQLQMANATYSLIAGALMIAGGLMGLILGWRKSFRIGLVLLCVSEIVAAFSPNIQAFIYGARVLTGAGASLTIPAVLGLIAGNYQGKDQAIAFSALAAASGIAAAAMPVVFGSLLDLVGFKITYLLLSLIFALVLIASVKVQDIAVSEQKPKLDIIGIILAAFGLLLVIVGTLKTPVWGVISPITAFSVFGLSPALIMVIAGLAILALLLVWEKRYEADGGLALMPAKIIYNKQVQTGLYIGALFWVGSSAPVAITIPYMQLVADYSTAQAGMTLIGMSLGTVIVAMLLPAKLSQLKVKTVCLFSLIGAAASAFIMSLGLEAGGVNGLLILGQTLMGCSLGAMASQCSIIVTDALDPQDAQQSGGIQATVRNIGYAVGIAIMGVTMLMVMTSDYKQQVAETTSFTQESKQTIEQLSAVPFLSDKEFTAYINEKNIIETQEVSTAVSINSQVRLNAARAGLYAVAIFMLMFLFSLKNLPSRSLMIKKDHEVDEVFEQFEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2F4</accession>
    <name>D0Z2F4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Oxidoreductase short-chain dehydrogenase/reductase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000605</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304845.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000605"/>
    <dbReference type="EnsemblBacteria" id="EEZ39585">
        <property type="protein sequence ID" value="EEZ39585"/>
        <property type="gene ID" value="VDA_000605"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0300">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1186478at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="259" mass="28265" checksum="F48283F985E01668" modified="2010-01-19" version="1">MSDLNTVTTSNLSATCPKSVLITGASSGIGRELALQYANDGYQVIACGQNNQKLVALMAEHPAIEALVFDVTDLEQTHKAFHSLPTIPSLIILNAGTCEYINHGEMDAQLVKRVFTVNVFGIANCIEALQARFDSHTHLVVMGSSASYLPLPRAEAYGASKAAIAYLTYSYALDVKEKGIFVSLVSPGFVKTPLTDKNDFAMPMLMSVSDAAQSIRAGITAKKTEIHFPAKFTYWLKLMALLPVNIQQWMVRKMTRRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2K1</accession>
    <name>D0Z2K1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000652</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304967.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000652"/>
    <dbReference type="EnsemblBacteria" id="EEZ39632">
        <property type="protein sequence ID" value="EEZ39632"/>
        <property type="gene ID" value="VDA_000652"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1268974at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020449">
        <property type="entry name" value="Tscrpt_reg_HTH_AraC-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00032">
        <property type="entry name" value="HTHARAC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="2">
        <location>
            <begin position="163"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="264" mass="30719" checksum="B2F60A0886F35813" modified="2010-01-19" version="1">MATSAIVITQYQGQQAQNLRNVPILLPSIVAVEQGEKQFQWHGRWIRFHKKNWLLIPAHSRITFVNNPHQTQFRSTQISFLIPPTAEMIQLSQQNADTVSNHLDSPEFIVDDEGRYLWQLLLSMPKELSQAIQQQLVNGLYQYLAEKGQLHLLYAPQEISWTEKLTQFFSQDPSQNYTIEQVCQQFGLSKATLMRRLNDESTQFREVLAQVRMGHALSLLQEKSQTVLELAQQCGYQSEVRFTQRFQKQFGLSPKQYQKTLHPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2P5</accession>
    <name>D0Z2P5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative permease of ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_000696</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the ABC-3 integral membrane protein family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305081.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000696"/>
    <dbReference type="EnsemblBacteria" id="EEZ39676">
        <property type="protein sequence ID" value="EEZ39676"/>
        <property type="gene ID" value="VDA_000696"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1108">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1421296at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037294">
        <property type="entry name" value="ABC_BtuC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001626">
        <property type="entry name" value="ABC_TroCD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30477">
        <property type="entry name" value="PTHR30477"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00950">
        <property type="entry name" value="ABC-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81345">
        <property type="entry name" value="SSF81345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="52"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="80"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="153"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="196"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="236"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="269"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ39676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="291" mass="31214" checksum="A4C48821E02DFBC3" modified="2010-01-19" version="1">MEIIRHWAQLGVDAGWLSESFSYAFMVNAIVAALLLGPLLGGLGTLVIAKRLAFFSEAVGHAALTGIALGVLLGEPPDNPFIGLFSFCMIFALLLHFVRNRTNVPYDTLVGVFLALALAVGAALLMYVARKINIHMLENVLFGSILTVTDQDLMILAVSCAIIVVLLIPTFNRILLTCISPDIARVRGHATHFYDYLFVMMITLVTIAAVKIIGAVLVGALLLIPGATARLMTKNMGSFVLLSALLATISCLVGTVLPMELKLPVPSGASIIIISALFFLMATCYRIIRKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2S6</accession>
    <name>D0Z2S6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Hypothetical rhomboid family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_000727</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000727"/>
    <dbReference type="EnsemblBacteria" id="EEZ39707">
        <property type="protein sequence ID" value="EEZ39707"/>
        <property type="gene ID" value="VDA_000727"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0705">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2053476at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="SSF144091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="51"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="136"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="160"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="Rhomboid" evidence="6">
        <location>
            <begin position="49"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="192" mass="21539" checksum="5AB7588E18AFAF93" modified="2010-01-19" version="1">MDLTIISRASVVFIGAIWLITITLFIVSLHGTHVDEYGLLPRHHLSNANYLIYPFIHGSFSHLLGNLLPFTVFALFIARKGLARLLIVCFLCWAGATLGVWIFGRISYHIGLSGIVYGTWAYLLSYALVKKSIKSVLLAVVTLILYGSMIWGILPLHPWLSFESHLFGFLTGILVGWYYASQDKLKDADDHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2U8</accession>
    <name>D0Z2U8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Adenine deaminase</fullName>
            <shortName evidence="1">ADE</shortName>
            <ecNumber evidence="1">3.5.4.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Adenine aminohydrolase</fullName>
            <shortName evidence="1">AAH</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000749</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>adenine + H(+) + H2O = hypoxanthine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:23688"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:17368"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.2" evidence="1"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305242.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000749"/>
    <dbReference type="EnsemblBacteria" id="EEZ39729">
        <property type="protein sequence ID" value="EEZ39729"/>
        <property type="gene ID" value="VDA_000749"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1816">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="554648at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000034">
        <property type="term" value="F:adenine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006146">
        <property type="term" value="P:adenine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043103">
        <property type="term" value="P:hypoxanthine salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01320">
        <property type="entry name" value="ADA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01962">
        <property type="entry name" value="Adenine_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001365">
        <property type="entry name" value="A_deaminase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028892">
        <property type="entry name" value="ADE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006330">
        <property type="entry name" value="Ado/ade_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43114">
        <property type="entry name" value="PTHR43114"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00962">
        <property type="entry name" value="A_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01430">
        <property type="entry name" value="aden_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="A_deaminase" evidence="2">
        <location>
            <begin position="9"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="197"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="16"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="275"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="276"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="1">
        <location>
            <position position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="335" mass="37582" checksum="931F11C204470EEB" modified="2010-01-19" version="1">MKNFILGLPKVELHLHIEGSLEPELLFTLAQRNQVAIPYNSPEALRAAYQFEDLQSFLDIYYQGASALCTEQDFYDLTWAYLLRCKQDNVIHTEIFFDPQTHTSRGISFETVINGIHRALVDGKASLGISSHIIACFLRHLSQESAIETLSSILQHQDKIIGVGLDSSELGHPPEKFEQVFQMAKQAGLKTVAHAGEEGPAQNIIDAINMLKVSRVDHGIRCVDDKKLIEQLIETQMPLTVCPLSNIKLRVFDSMEQHNIIELLRKGVAVTINSDDPSYFGGYMSDNFMSVYNAHSMTKDELAQLTTNAINASFINDEQKAAYRHQVQAYLAQNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z311</accession>
    <name>D0Z311_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">YkuD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_000812</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the YkuD family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000812"/>
    <dbReference type="EnsemblBacteria" id="EEZ39792">
        <property type="protein sequence ID" value="EEZ39792"/>
        <property type="gene ID" value="VDA_000812"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3034">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071972">
        <property type="term" value="F:peptidoglycan L,D-transpeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd16913">
        <property type="entry name" value="YkuD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005490">
        <property type="entry name" value="LD_TPept_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038063">
        <property type="entry name" value="Transpep_catalytic_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03734">
        <property type="entry name" value="YkuD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141523">
        <property type="entry name" value="SSF141523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019960" description="YkuD domain-containing protein" evidence="4">
        <location>
            <begin position="23"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="YkuD" evidence="5">
        <location>
            <begin position="75"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ39792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="239" mass="27353" checksum="3EC99EE140769660" modified="2010-01-19" version="1">MKILRAFWGIGLMSVLCQPVLASNYSYNDFPPKGSRTVDDVIKRYQPIVEPRLKIDFARAEVSYPPKKIALFAMKNEQKMELWAEEGDTWHLIKNYPITKLSGVMGPKKREGDKQIPEGIYQVEFLNPNSQYHLSMKLNYPNDFDLKYAKLEGRTKPGTNIFIHGKESSVGCLAIGDVAIEELFVLAKNTGIDNIDVVISPYDPRTRTLVPTLSEPYWTSILYRDITHVAQQFDSKRHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-02-10" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z393</accession>
    <name>D0Z393_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Leucine-rich repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000894</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305654.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000894"/>
    <dbReference type="EnsemblBacteria" id="EEZ39874">
        <property type="protein sequence ID" value="EEZ39874"/>
        <property type="gene ID" value="VDA_000894"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4886">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1614949at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="189" mass="20856" checksum="E07192D4CE952970" modified="2010-01-19" version="1">MTKSLLLLNQLKIIVCIVFFLCSSNVFAKVVLSKVHLLNYTDTYGNLYFPRFSDLQLPSPLDVHGSLIASHTKISPLPSPLKVEGNADLSYTNLTFLPNTLKVGGYLNLAHSQVNRLPEGLMIPGDLSLISTPITYLPNNLFVGRNLYLNNTKLTYLPLNLKVGGNLYLSGSKIKEIPESAQIKGRVIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3E7</accession>
    <name>D0Z3E7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000948</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305806.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39928">
        <property type="protein sequence ID" value="EEZ39928"/>
        <property type="gene ID" value="VDA_000948"/>
    </dbReference>
    <dbReference type="GeneID" id="57343174"/>
    <dbReference type="eggNOG" id="ENOG5030B26">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2051804at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="59" mass="6792" checksum="AA128498EDB7281C" modified="2010-01-19" version="1">MLRLIVLALVGFGIYLGITYKDKIDDARNVRPFEKVQDAVEDARDNVKDKFEELKGHNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3F4</accession>
    <name>D0Z3F4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lactoylglutathione lyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000955</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305825.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000955"/>
    <dbReference type="EnsemblBacteria" id="EEZ39935">
        <property type="protein sequence ID" value="EEZ39935"/>
        <property type="gene ID" value="VDA_000955"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1984437at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004462">
        <property type="term" value="F:lactoylglutathione lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018146">
        <property type="entry name" value="Glyoxalase_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00934">
        <property type="entry name" value="GLYOXALASE_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="2"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="161" mass="18619" checksum="3DAE75570C6A331D" modified="2010-01-19" version="1">MKMNHVGIMVGDMDKAVEFYTKALGLKVVMGNTKVIEERETAIGRMCIAVFGEGFKGFNIAHLVTTDGIGVELFEMKERQERHEVDFSRLGIFHFCLQTDDFETAIKNIEQYGGKARMDIMRYHPEDDNKPAQMIYMEDPFGNLFELYSHTYEETYASDYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3H2</accession>
    <name>D0Z3H2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">TPM_phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_000973</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305879.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000973"/>
    <dbReference type="EnsemblBacteria" id="EEZ39953">
        <property type="protein sequence ID" value="EEZ39953"/>
        <property type="gene ID" value="VDA_000973"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1512">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1720318at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007621">
        <property type="entry name" value="TPM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04536">
        <property type="entry name" value="TPM_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003020040" description="TPM_phosphatase domain-containing protein" evidence="5">
        <location>
            <begin position="21"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="171"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="TPM_phosphatase" evidence="6">
        <location>
            <begin position="31"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="249" mass="26767" checksum="56BDE469D5BCD757" modified="2010-01-19" version="1">MRKNLLICGFLLFASQLCFAQPSFPALTGRVVDDAHILTQPQRQALNTLLAEEEKSSSNQVVIVTVPSTGGIPIADYGYQLGRKWGIGQKEHNNGVLLIIAYNDKKMRIEVGYGLEGVLPDATAYSIINHEIKPQFKAGRFYQGISNGTKAIIAAIHGEYKPIVEEDQPPYDFYLFVLFVVVIQIIAYTRRRKNGGKYYRSGRDGFTTGSFGSGGIHRHGSNHSGGFGGSSGGGFSGGGGGFGGASGGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3N2</accession>
    <name>D0Z3N2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Amidohydrolase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001033</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306037.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40013">
        <property type="protein sequence ID" value="EEZ40013"/>
        <property type="gene ID" value="VDA_001033"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1574">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="751534at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01300">
        <property type="entry name" value="YtcJ_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013108">
        <property type="entry name" value="Amidohydro_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033932">
        <property type="entry name" value="YtcJ-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07969">
        <property type="entry name" value="Amidohydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019381" evidence="1">
        <location>
            <begin position="25"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="domain" description="Amidohydro_3" evidence="2">
        <location>
            <begin position="97"/>
            <end position="584"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="657" mass="72945" checksum="F8A551EFA0C8EAC2" modified="2010-01-19" version="1">MNLMKVKKTSLAVALSFVSTGAFAQGSSLQDVISATALNPETTIYTAKDIVTMDGNKQNAQAVAVVNHKIVAVGSLEEVKSKVGDKNVTINNQFQDKIIVPGLIDQHLHPLLSSLTMTAEIISMEDWVLPTGTVKAVSNREDYLKRLADADKKLTDPNELLLTWGFHHYFHGKLTKDDLDKINNKRPIIVWHRSAHEFILNTAALKKYGITADYIAKQSKSAQEQINLPEGHFWEQGMFVLLPKIAPAIATPKRLKDGLEFTEQYLHANGITTSAEPGGLVSKQLQEAQNAVLSDAQTPFRFYFIPDGKTMALEHLNDNMIGATEEMLSWGEGNTAFLPKQVKLFADGAIFSQLMQMKDGYLDGHEGEWMIEPEIFAQAFTQYWDAGYQIHIHQNGDKGLDMVLKSLKENMKRNPRKDHRTTIVHFGFSTPEQVKELKELGAIVSANPYYTVALADKYSEAGVGPERSNEMVRLGDVAKEGISISLHSDMPMAPAQPLYLMWSAVNRTTFSGRVAGPEQRISAEQALKAVTIDAAYSLQLENQVGSIEPGKLANFTILDENPLTIDPAKIKDIKIWGTVLEGRIQPIKLEQKSVPQANVSGDFVDMHKLTPDQSYKVVMESVRSSKHQQHTHTSACSHDNPLGYAVVSLWQEQMNTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3T5</accession>
    <name>D0Z3T5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Threonine efflux protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_001086</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306187.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001086"/>
    <dbReference type="EnsemblBacteria" id="EEZ40066">
        <property type="protein sequence ID" value="EEZ40066"/>
        <property type="gene ID" value="VDA_001086"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1280">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1927576at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001123">
        <property type="entry name" value="LeuE-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30086">
        <property type="entry name" value="PTHR30086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01810">
        <property type="entry name" value="LysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="44"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="126"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="149"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="208" mass="22864" checksum="6F1E2887E4CC5C46" modified="2010-01-19" version="1">MHGIAYFDVFLHVLVVWSLAAITPGANVFLTINTSLASGKANGLACAFGVTLAVGLWGLAGISGIVIMLSLYPWLFTVMKILGGTYLIYLGLSRFKTVRRGYQLAGQVEDKHSWGASAIRSFTTSILNIKTGLFVISLFSLAIPREHDYRIAILVIATMMLITFVWHCLLALVFSHSRAQKTYFRLQRYIDALTGGLFTLLGIKLITS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z486</accession>
    <name>D0Z486_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000342</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304097.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000342"/>
    <dbReference type="EnsemblBacteria" id="EEZ39324">
        <property type="protein sequence ID" value="EEZ39324"/>
        <property type="gene ID" value="VDA_000342"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0665">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1087129at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAO" evidence="1">
        <location>
            <begin position="32"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="426" mass="47541" checksum="A2CF7C9C5E1608EB" modified="2010-01-19" version="1">MSNDSQYIDSYYQATINAIPEQPQLDQSIEADVCVIGGGMTGLNAAIELRKKGYSVVVLESQRLAWGGSGRNGGQCLVGYCLGLREVDETYGPQWGKQLWDLSSEAIDIARERIEEFNIDCDFQHGYIELALKKSQEKELKSWYDLKQTRYEYPSASWWEKDQIQQVANTERYLGGLFDSNSAHMHPLNYTLGLAEAAISLGASVFENTPAIKIEQGKPHTISTPKGQVKAKQVLLACNAYLDGLNRKAQSVVLPVASYIAVTEQLGDRQPISNMMAMSDLNNSLDYYRPTPDGRILFGGVNHPFNGEYSDSKERLRQRMLKVFPQLSDVKMEYHWGGLFAVTRSYMPQIDHLGNDIYVSHGYTGHGVGLTNIAGRVVAEAMSGTAERFDVFARIKHGWIPTPEILRKPALAMAIWKARLEDSLGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z494</accession>
    <name>D0Z494_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MOSC domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304121.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000350"/>
    <dbReference type="EnsemblBacteria" id="EEZ39332">
        <property type="protein sequence ID" value="EEZ39332"/>
        <property type="gene ID" value="VDA_000350"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2258">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1643056at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030151">
        <property type="term" value="F:molybdenum ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005302">
        <property type="entry name" value="MoCF_Sase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011037">
        <property type="entry name" value="Pyrv_Knase-like_insert_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005163">
        <property type="entry name" value="YiiM-like_3-alpha_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03475">
        <property type="entry name" value="3-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03473">
        <property type="entry name" value="MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50800">
        <property type="entry name" value="SSF50800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51340">
        <property type="entry name" value="MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MOSC" evidence="1">
        <location>
            <begin position="27"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="226" mass="25662" checksum="0CAD2295BDFE2998" modified="2010-01-19" version="1">MQKNNVIGVYCGSVSDMDRIETAMFKQSVSGRIYLSETGLEGDSCASTKHHGGTERALHQYPVEHYAFWQQQYGVDKEWCAPGMGENISSQGMTEENVCIGDQYQWGEAIIEVSQPRSPCYKLNTRWNVAEFSVQMQKLSRCGWLYRVVKPGLVSVSEPLVLLSRPENALTIKQVCDIYFGDPLNHLGLEALQQQTALSHNWQTTITRRLESNELENWNFRLLGHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4E2</accession>
    <name>D0Z4E2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative molybdenum cofactor biosynthesisprotein Mog</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000398</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304256.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000398"/>
    <dbReference type="EnsemblBacteria" id="EEZ39380">
        <property type="protein sequence ID" value="EEZ39380"/>
        <property type="gene ID" value="VDA_000398"/>
    </dbReference>
    <dbReference type="GeneID" id="57343211"/>
    <dbReference type="eggNOG" id="COG0521">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1877633at2"/>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00886">
        <property type="entry name" value="MogA_MoaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.980.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036425">
        <property type="entry name" value="MoaB/Mog-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001453">
        <property type="entry name" value="MoaB/Mog_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008284">
        <property type="entry name" value="MoCF_biosynth_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00994">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00852">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53218">
        <property type="entry name" value="SSF53218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00177">
        <property type="entry name" value="molyb_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01078">
        <property type="entry name" value="MOCF_BIOSYNTHESIS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MoCF_biosynth" evidence="3">
        <location>
            <begin position="7"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="177" mass="19355" checksum="BA66E7737A79C32A" modified="2010-01-19" version="1">MTKAKIGIVTVSDRASAGVYEDISGQAIIDTLNDYLTSEWEPVYQVIPDEQDVIEATLIKMTDEENCCLVVTTGGTGPAKRDVTPEATEAVCDRMMPGFGELMRAESLKFVPTAILSRQTAGLRGDSLIVNLPGKPKSIRECLDAVFPAIPYCIDLMEGPFLVCNEDVIKPFRPKQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4E8</accession>
    <name>D0Z4E8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000404</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304272.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39386">
        <property type="protein sequence ID" value="EEZ39386"/>
        <property type="gene ID" value="VDA_000404"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502ZEUJ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1534908at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="230" mass="26635" checksum="16D8FD0BDF2A5F5B" modified="2010-01-19" version="1">MEKLDLDEAQQIERLYTTSPVYEWELIVNTISFRTKMMYIMLLGSFGVAIVFFLLGFSWLSLVPIVVGSFLTPWFRYLVNSDKRYYYAINQYGMYSTEEQIIPEIAYTIVRYSAWVGCGICLFAAILVGPIAFVGAGGAALLSFQMTNFRSVPYKSQCLFDNAAILKNYRENDYLLRTENSMIPLIIPECKLPRIINVIKQYNDSFEEEFVDLYKDSKFQARPIILEIVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4H8</accession>
    <name>D0Z4H8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000436</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304359.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000436"/>
    <dbReference type="EnsemblBacteria" id="EEZ39416">
        <property type="protein sequence ID" value="EEZ39416"/>
        <property type="gene ID" value="VDA_000436"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1361">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2067">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2885">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3188">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="47812at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001434">
        <property type="entry name" value="DUF11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01345">
        <property type="entry name" value="DUF11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01451">
        <property type="entry name" value="B_ant_repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF11" evidence="1">
        <location>
            <begin position="755"/>
            <end position="835"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="2196" mass="244977" checksum="9D0FAF1A55CE6908" modified="2010-01-19" version="1">MALLNVITKMKYLVIFILLSVSSTALGLTSAGTKISNQAIMTYFDSGSGETIRVLSNISYVKVENVYDVELTPDTAGGAATEKNVAPGSIVSIPHTVTNTGNIKDSYIITVDNKDGDNGNLTSPDTNEIKIYFDTNGNGIHDPGEPELNKNDAGDYIIPQLKPGESINLVYQVEIPTTDKDDDFYDLTTAVTSQAKPSVVKTSDTRLTVFDGPIVNLTIENSPVCQQTVTSFNEIDFRVNYTSIGLTKPEDSAQPYNIFVKSESSGDIVQVSHTGVLISVNLPANITLLQDKIINGNPAKDHSPITLVSPENNFDGGVVLVGINNNFLFEQADHDLDWYVYSSWDGTGNVEKVGFLVKSDYMKPNSSGHFTYYTQVNNVRGQQPFKIYSEAEVNLSSTDQNISRSGEVCNTLIGEDEANLIDFELLDDQVLTPDSDFTIEYSNHDHFIPTNFYYHADTTGFDEKFDGIHAQIILPQGNEHASTIDIIGPASSNYPVTLRSTYGDSFHWVFAETGPNTGIFRSVIPAHAVAPKDNYTRTGTNHCLEDVVTPWRTGSAIRPELLANIDQTINFSGFNLNGSTAFDCEIQSNPDDELVIEVFDPRNGNKIILTDLAYISPQFVVFDATNFNGIENAIVKFYQTENNVAPAAKIRVPNVDGLTPVAEATSDAEGRVFFPKLAPIDGNQYYISVVPPETHVWPSSYTVLDNFNLHNVVPASYGPFGNQDVENSGLFPIAVRDRVNTFDIPIDPKNLDRRLTIQKDADKDSAEIGSFVKYTITIKNNLPDSQLFNAQVYDSMPYGFKYMEGSTRLNDQPYQDPIRIDTYTYRFDIGTLNGSSQPPENGTYKLTYVLQLTAGAVDSDGINSVYADAATFGGSSGSRITSNVDKYQVKVTQTGVMSDRGIIFGKVFIDAQCNDIMKNQMWPIGGVKLYLETGDYVITDENGQYSMFGIKPGNHVIKVDKQTLPVGIELQPIDTRNAGKGDSRFVDMRRGEMHRADFVAPCPTENQEAIYQELLERNTNINGEWLFKTAESFKGLQYDAKPKALKSEELQSGVISGPSTSSTNKVEKASSSSSALSVFKGFALESRKGSKKDLESIISIYPKEVQDEAYVYPGAENQSSIRFGFSDSQDKLKALRTALSHYKIETTIVPTAYSSIPQEAKFRIDNVLQEAIPLPEKEAKNITRAEAEKGTWYWPTNEYSYDGRFIAVIRGDVEPTLYVNGQAISVDQLGERIINKRENAQIVGWYGVPLEDGENVVEIKTVDPFGNERLVLGKNFSHPKSAKRISVVADGDVLRADGGRSVIPVIIKLYDENNNLARGTYFVTLNTDHGDSWLDPDIQENETGHQVRVINGEKTVYLRSTENTGQINVQASVEDFSDSIKVYQVAAKRPLFVSGILNYTGRYGRFSGEEPPAQADGYEDKNYSHDERAAAFMKGNIKGGMHLTLSYDSNKSDEDFYREISPDSYYPMPGDASIKGYDARSTSKLYVKLEKERHFAMWGDYNTADGADESDIGRTSQVLNGFNSMYNDGRVMAQLYGARPEDLHKVVEFSGNGTAMFYSIGDTRIVRHSDTVNLVTYDRDNQGLVLRQQPLTRYIDYTIDYFTGDMRFNRVVPTYDPDLNPIKVRVSYDVEGDGDAYTVAGARLSYLFTPYLLAGASYEYNDNDVEGYNIGSVWVNYDFDSKTQITAAVAHMSHEGSESANNLTSSTGTDSKLKDGMAYKLRIKRDWSAQAVTELEYVYAEEGYTNTTGGVTPARQEFRLRHRQKLTGLMNLNIEANHSESLIHTEKQQSIGATVDTKILGSQWTTRLGSRYIKNETETDSEEYTTAIVGVGRTFSVWGRPGRFDTEYEQSFGHDSKRRFNIKADLKVHKQASIYTQYEYIDSLSGITNLGSGTTSLFTAGIDVDWLHGGSTFSEFRQRGASDGRSLELANGYRGRFEMVSGISIDPSIEYVEVLEGDGTSGLALSLGLADIRNPNYKTTGRIEYRHGDSEDYYGILGAWVTRLSQDWSGLVREEYRYIDKDGAQNTWSNHFSLGFAYRPRLTNRYHMLGAYEWKTERNDATRNAHILSTHQNYQLSPQWTISGRVGLKWEDFTEYEQDYDSVATIIDGRVIYYINRRWDLDLHAGMLGTDWFDSRRYSFGAGVNYLVMENLRAGIGYNVIGFDDDDLDPQGYNLQGFYFDIMFKLDEDLFGWLSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4J0</accession>
    <name>D0Z4J0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000448</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304393.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000448"/>
    <dbReference type="EnsemblBacteria" id="EEZ39428">
        <property type="protein sequence ID" value="EEZ39428"/>
        <property type="gene ID" value="VDA_000448"/>
    </dbReference>
    <dbReference type="GeneID" id="57342614"/>
    <dbReference type="eggNOG" id="ENOG50331NB">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1952072at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021284">
        <property type="entry name" value="DUF2750"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11042">
        <property type="entry name" value="DUF2750"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="117" mass="13381" checksum="B5F7071DA725864D" modified="2010-01-19" version="1">MSKLTSDIQANKELFVTESQETRLVWTLRNEEGEWLSVESSEFEDSEVMPFWSNEADAKAQCSDEWAEFFPSELPLDIFLEDWMITLAEDGVLVGLNWNAQLEGVEAEPADVAKLYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4K6</accession>
    <name>D0Z4K6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Branched-chain amino acid transport system carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_000464</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the transport system for branched-chain amino acids.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell inner membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the branched chain amino acid transporter family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304436.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39444">
        <property type="protein sequence ID" value="EEZ39444"/>
        <property type="gene ID" value="VDA_000464"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1114">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1533843at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015658">
        <property type="term" value="F:branched-chain amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004685">
        <property type="entry name" value="Brnchd-chn_aa_trnsp_Livcs"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30588">
        <property type="entry name" value="PTHR30588"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05525">
        <property type="entry name" value="Branch_AA_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00796">
        <property type="entry name" value="livcs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="37"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="72"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="114"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="143"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="184"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="224"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="270"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="303"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="332"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="366"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="404"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ39444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="447" mass="47302" checksum="79514E3D33A539C3" modified="2010-01-19" version="1">MKTQDLLAIGLMTFALFLGAGNLIFPPSLGLDAGTSLFTAMSAFLVTAVGLPAFTIIVLGRISCTQYLTNALPKWLATTFWVLLFTAIGPAFGMPRAVTVAYEMGIKPFMTQDHLMVFSIIFSALTLLLAFKPGKLVDYIGKFMTPALILMLLALGLSAFISPLGVPGHPVGDYQHKAVTSGLIQGYMTMDAIAAVGFGWVIIQAIRAKGITEPKMISSVTFKVALIYAVLMGGCYIAMGYVGATASAIAEHGVNGSVILTRYVAGEFGPYGQYLLAAIIIMACLTTTVGLTNACAEYYKETFNASFGLTATCVVVLTGIIANFGLEQILKVSLPAILVLCPVAIALVLASFTASTVSVSAYTHTAMLFTAAVFGSVDAISILGKMPKELNDLFQHALPLYNAHASWLLPCLVILVLTSALGTSKLGGERIGRIDYRLKTQASNSLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4M5</accession>
    <name>D0Z4M5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ATP-dependent RNA helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_000483</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the DEAD box helicase family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000483"/>
    <dbReference type="EnsemblBacteria" id="EEZ39463">
        <property type="protein sequence ID" value="EEZ39463"/>
        <property type="gene ID" value="VDA_000483"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0513">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4 8" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="6">
        <location>
            <begin position="1"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="7">
        <location>
            <begin position="185"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="353"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="374"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ39463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="394" mass="44181" checksum="A95AFE0C6AABB1C4" modified="2010-01-19" version="1">MILLGKDVLAAAQTGTGKTASFVLPMLERFNDGVKVRPKRVRGLILAPTRELVAQVAENIEKYSKHLNIKTLAMFGGVEYKHQKQALIEGVDILVATPGRLLDMCTQRAIHLDEVETVVLDEADRMLDMGFIEAINKVMDRLPLDCQQLLFSATMTRQVRELARTAIENPIELSEISKGNAAASKIEQWLVTVDKDMKSSLLSHMIKENDWDQALIFIETKHGAAKLVEQLAKRDIYAEAFHSGRSQAVRSQLLEDFKSGQLKLMVATGVAARGIDIDNLKRVINYDLPYPAEEYIHRIGRTGRAGASGEAISFVSKDNFKNLCMIESRLGHLLERRVVEGFEPRKPVPVSILNYKPKHLREGGAAPKEGKKAIPHNRTRRHNKRNKPQKSKPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4M8</accession>
    <name>D0Z4M8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Cytochrome c oxidase subunit III</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">VDA_000486</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Energy metabolism; oxidative phosphorylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CcoP / FixP family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304498.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000486"/>
    <dbReference type="EnsemblBacteria" id="EEZ39466">
        <property type="protein sequence ID" value="EEZ39466"/>
        <property type="gene ID" value="VDA_000486"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2010">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1315115at2"/>
    <dbReference type="UniPathway" id="UPA00705"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006119">
        <property type="term" value="P:oxidative phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.280.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032858">
        <property type="entry name" value="CcoP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038414">
        <property type="entry name" value="CcoP_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008168">
        <property type="entry name" value="Cyt_C_IC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004678">
        <property type="entry name" value="Cyt_c_oxidase_cbb3_su3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13442">
        <property type="entry name" value="Cytochrome_CBB3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14715">
        <property type="entry name" value="FixP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00605">
        <property type="entry name" value="CYTCHROMECIC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00782">
        <property type="entry name" value="ccoP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 17" id="KW-0349">Heme</keyword>
    <keyword evidence="10" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="14" id="KW-0406">Ion transport</keyword>
    <keyword evidence="13 17" id="KW-0408">Iron</keyword>
    <keyword evidence="15 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0677">Repeat</keyword>
    <keyword evidence="7 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 18" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="14" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="56"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="19">
        <location>
            <begin position="124"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="19">
        <location>
            <begin position="213"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="19">
        <location>
            <begin position="307"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="19">
        <location>
            <begin position="451"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="19">
        <location>
            <begin position="598"/>
            <end position="701"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00029635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="EEZ39466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="734" mass="81206" checksum="9E63521C3D5C368E" modified="2010-01-19" version="1">MNAFWNTWVITLTVLFLAIMVGVILFYWQKRASSDPHRTLDTFDGIQENDGAVPKLLFIAYLISIILTLGYFVLYPGLGNWPGLMHWSSTSQATVPSQTTLEAQYQKAKLNAASPLEELSQNATIVNTGQSLFQTHCAACHGDQGQGQKHFPNLLDNYWLYGGTDQDILHSIKQGRNGVMAGWENILTSEQITHVSQYIASLEPERVVNAPEVNFELGSAIYTENCVACHGEKAQGNPILGAPNLTDNIWLHGGSIDEIKHTIRQGLNNVMPAFQSQLNSLEISAIAAYVKYENKLHIERKQSLDPELIAKGRYLALAGDCIACHTSEGGQPFGGGLGFVTPFGTLYSTNISTHPDYGIGDYTYQDFYDSLHKGKGKNGYLYPAMPYSSYQYVTEEDTRAIWTYLQSIVSVNTVNTENKMIFPSNIRLGLLAWNIAFLDTNPLEYPSYRPATWKRGKYLTMGLGHCSECHTPRNIAQALEPKKLFQGNLIDGWQAPDITAEQLYETGWNIVSLTDFLKTGHSEKGTAFGGMAEVVKNSTRHLTRQDVEAIAEYLIAGDKYNEIEPHIVPIIPPGFGDLANRPVTQTINEIDDSLNIASNTKTGIETLDIQNHEEAMYNLYAQTCGACHGPDGKGRAGIAPALLNNGIIMHKDPYDTIAVAIRGLMPSYMNRGTNFMPMSSFNTVLSDAQLAQLLTFVRNRLGGRTVIITAKDVTNVRKELEKSGYIGAIHQPME</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4R5</accession>
    <name>D0Z4R5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Succinyl-CoA synthetase alpha subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000523</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304611.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000523"/>
    <dbReference type="EnsemblBacteria" id="EEZ39503">
        <property type="protein sequence ID" value="EEZ39503"/>
        <property type="gene ID" value="VDA_000523"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4222">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1387978at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003020085" evidence="1">
        <location>
            <begin position="19"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="domain" description="Endo/exonuclease/phosphatase" evidence="2">
        <location>
            <begin position="38"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="459" mass="50638" checksum="6ED7E86887F56E8B" modified="2010-01-19" version="1">MKIIKTIAAAAISTALLAGCNSDNNIFTDPTSSQVSIATFNLSFDRKTFEQLVTEMQISPAKQQELVDGFIANTLNGTDKTLAEKVIQIRNVAAIIQTKRPDIILLAEFNNDGIGENKAALKGFQDNYLSVAQSPNSIDGGDKLEPIHYPYFESYATNTGKMSGLDLNNDGKVNSGPNDAWGFGTYHGQYAFALMSKYKIDTANTRTFQNFKWKDLPTAENPIITNCNDPKNAIPAGMSCGDNWYTPEEWDQVLLSSKNHVDAPVIVQTPNGEETIHILMSHPTPPVFDTVTQNNKMKNRDEIQFWHEYISGQSFIYDDNGQHGGLAQNAKFVIVGDLNADPLAGDGFTGTIDSLLKHHRVNQEATIGTYVPTSFGAENCYPSKECRQDNPYPNRLTSTFGLRVDHAIPSENLAIIDSAVYWPAENESGHLLMNDSRIGYGNGKSISSDHRMVWIKAQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4X8</accession>
    <name>D0Z4X8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000211</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306617.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000211"/>
    <dbReference type="EnsemblBacteria" id="EEZ39195">
        <property type="protein sequence ID" value="EEZ39195"/>
        <property type="gene ID" value="VDA_000211"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3316">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1667004at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032874">
        <property type="entry name" value="DDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13610">
        <property type="entry name" value="DDE_Tnp_IS240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_IS240" evidence="1">
        <location>
            <begin position="70"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="228" mass="26821" checksum="9284359ACD70E4F2" modified="2010-01-19" version="1">MQFTGYHFPSDIIIQAVRYYVAYKLNYRDIEEIFAERGIRVDHATINRWVIRFAPLIEQIARTIKHYVSSSWRMDETYIKIKGKWWYYYRAVDKYGDIVDFYLSQTRDEKSAQAFLRKAIRTNGLPDQVVIDNSGANARALHHMNVKLWKSVVFMLNLIEIIDAKYLNNIVEQSHRPIKQKMYQALGWKSVEGASATMSGQEVWTQIKRGQVGELSLPVWERFYALIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z512</accession>
    <name>D0Z512_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mutator family transposase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_000245</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">Required for the transposition of the insertion element.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the transposase mutator family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306717.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39229">
        <property type="protein sequence ID" value="EEZ39229"/>
        <property type="gene ID" value="VDA_000245"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3328">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="792870at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001207">
        <property type="entry name" value="Transposase_mutator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33217">
        <property type="entry name" value="PTHR33217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00872">
        <property type="entry name" value="Transposase_mut"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01007">
        <property type="entry name" value="TRANSPOSASE_MUTATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0814">Transposable element</keyword>
    <keyword evidence="4 6" id="KW-0815">Transposition</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="402" mass="46593" checksum="5C554948C8A0F3FA" modified="2010-01-19" version="1">MDKKALEAFAREAAKSIKTESDLDDFRKMLTKVTVETALNAELDEHLGYQKHQSRTSSNSRNGYSGKSIITDDGEVDIEIPRNREASFEPQLIRKHQTRFQSMDDKILSLYAKGMTTREIVATFKEMYDADVSPTLISKVTDSVLELVIEWQSRPLDEVYPIVYLDCIVIKVRQDKQVINKAVYLALGVNMEGQKELLGMWLSETEGAKFWLNVLTELQNRGVKDILIACVDGLKGFPDAINTVFPETQIQLCIVHMVRNSVKYVPWKDYRAVTADLKKIYQSATEDEALLALEQFSDRWDSKYPQISRSWTAHWDNLNTLFNYPEDIRRAIYTTNVIESLNSVIRKAIKKRKLFPADESARKVIYLAIQDSSKKWTMPIRNWRQALNRFMIMFEDRLTEYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z528</accession>
    <name>D0Z528_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DNA-binding protein H-NS</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_000261</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Nucleoid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the histone-like protein H-NS family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000261"/>
    <dbReference type="EnsemblBacteria" id="EEZ39245">
        <property type="protein sequence ID" value="EEZ39245"/>
        <property type="gene ID" value="VDA_000261"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2916">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009295">
        <property type="term" value="C:nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027444">
        <property type="entry name" value="H-NS_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037150">
        <property type="entry name" value="H-NS_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001801">
        <property type="entry name" value="Histone_HNS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027454">
        <property type="entry name" value="Histone_HNS_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00816">
        <property type="entry name" value="Histone_HNS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002096">
        <property type="entry name" value="HnS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00528">
        <property type="entry name" value="HNS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNS" evidence="7">
        <location>
            <begin position="57"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="DNA-binding region" evidence="5">
        <location>
            <begin position="82"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="50"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="64"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR002096-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ39245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="99" mass="11580" checksum="19F46239E5E6DAC6" modified="2010-01-19" version="1">MEKLTQVVNERAQEEEQLRAENREKEEKLEMYRQLLLADGIDPEELIASMTASKSKKSSRTPRPAKYRYTDEDGQEKTWTGQGRTPKFLADKNLDDYLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z531</accession>
    <name>D0Z531_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000264</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39248">
        <property type="protein sequence ID" value="EEZ39248"/>
        <property type="gene ID" value="VDA_000264"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="41" mass="4601" checksum="3E53A1B5FAF719A5" modified="2010-01-19" version="1">MAAFDPSIRVPSDIAAMVNAKFDKFSEESKEKSHKFILGEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z533</accession>
    <name>D0Z533_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mutator family transposase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_000266</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">Required for the transposition of the insertion element.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the transposase mutator family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306778.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39250">
        <property type="protein sequence ID" value="EEZ39250"/>
        <property type="gene ID" value="VDA_000266"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3328">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="792870at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001207">
        <property type="entry name" value="Transposase_mutator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33217">
        <property type="entry name" value="PTHR33217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00872">
        <property type="entry name" value="Transposase_mut"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01007">
        <property type="entry name" value="TRANSPOSASE_MUTATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0814">Transposable element</keyword>
    <keyword evidence="4 6" id="KW-0815">Transposition</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="402" mass="46607" checksum="4EE7EFC11604C31B" modified="2010-01-19" version="1">MDKKALEAFAREAAKSIKTESDLDDFRKMLTKVTVETALNAELDEHLGYQKHQARTSSNSRNGYSGKSIITDDGEVDIEIPRDREASFEPQLIRKHQTRFQSMDDKILSLYAKGMTTREIVATFKEMYDADVSPTLISKVTDSVLEQVIEWQSRPLDEVYPIVYLDCIVIKVRQDKQVINKAVYLALGVNMEGQKELLGMWLSETEGAKFWLNVLTELQNRGVKDILIACVDGLKGFPDAINTVFPETQIQLCIVHMVRNSVKYVPWKDYRAVTVDLKKIYQSATEDEALLALEQFSARWDSKYPQISRSWTTHWDNLNTLFNYPEDIRRAIYTTNAIESLNSVIRKAIKKRKLFPTDESARKVIYLAIRDASKKWTMPIRNWRQALNRFMIMFEDRLSEYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-06-02" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z586</accession>
    <name>D0Z586_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">IncF plasmid conjugative transfer protein TraG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000136</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306950.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000136"/>
    <dbReference type="EnsemblBacteria" id="EEZ39120">
        <property type="protein sequence ID" value="EEZ39120"/>
        <property type="gene ID" value="VDA_000136"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="29010at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012931">
        <property type="entry name" value="TraG_N_Proteobacteria"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07916">
        <property type="entry name" value="TraG_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="326"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="362"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="416"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="domain" description="TraG_N" evidence="3">
        <location>
            <begin position="7"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="544"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="654"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="675"/>
            <end position="690"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="830" mass="90049" checksum="C374F99F356C1006" modified="2010-01-19" version="1">MANVYDVYVFSGGATAEKVFNAIATFLRGDSYGHLLAIVGMCALLMTMFRFFTSRDHTHLLSYIAVNLTVSSMLLIPTATVRIDDSSMSGRTYFVDNVPIGVAAPIHYATTFMYGLARATDVIFVQPDEAAYTKSGMLFGSKLVGLSQRIGIQDGELKQLWGQYTQNCIRKDITINKKYTWTQFAQAGDIFEFLKNNRPSPVRRIAMNGAFPTCQEALPLLENKFRDEANKSFRLMSTETVINGWATNEALLQNAVASSYRTFHNINKSASDLLKQNIAVNGVKSGLLDSAASTGATAAAFNYAATHSQMQTQSFMTSMGINAAEWLPIVNSVLILLLACSSIPVFLAAFIPGMTVRVLKGYLGGFFYLALWPFFFTVINLIMTYSLQYAGAESTNLLHGMSLAGSSPLQAMHYKYAAIAGWLMMMVPIISKYALTGGLVMAGSLGQQFLGAMGSNAARSSQAAASGDMTYGVVQTDTWHSNSMSGNKVDTAYSNQSYGAQVQRADGSSVNYLPGGNAVYSSRGAISTTGFDINSSEVQSRALQNSYTEAQRATSQARTAYSQSSGSVTDQLMSLSSSASRNTSYGEGTQYSSNSSTQNSLSKLDGVVAEEAKAKGVSKEEAYKQMVDNYLDYNASGSASLGAGVGEFGNIKGGANISKGRRYSDTESSTDSQRQDRTSRTSNSRQNQFNDLMSSIEQYGTSGRTEDLHGFNQQAMSTLSEAIKESKDLAKTVDSSIAKEQAYSAALQDSQTGSLSVNTNLMPEFQAYVARRRPENVEAIMNGNTPAINEERDLFFQAFMSERFSNYNPELKQAWDDSSMNRPAQSVQGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5B7</accession>
    <name>D0Z5B7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000024</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the transposition of the insertion sequence.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000005">
        <property type="protein sequence ID" value="EEZ39039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39039">
        <property type="protein sequence ID" value="EEZ39039"/>
        <property type="gene ID" value="VDA_000024"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3316">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032874">
        <property type="entry name" value="DDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13610">
        <property type="entry name" value="DDE_Tnp_IS240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="Integrase catalytic" evidence="3">
        <location>
            <begin position="76"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="198" mass="23249" checksum="E8EA8E72BBF8ABF3" modified="2010-01-19" version="1">MLKLGVLTFIRVLHGLLWLPTSIYIILLAVRYYVSYKLSYRDIEEILAERGSFVDHSTINRWVINFAPMIESKARQIKRPVSSSWRMDEIYIKGAWWYYYRAIDKFGDIVDFYLSKERDEKGAQAFLRKAIRTNGLPEKVVIDKSGANAQALHNMNIQLWKSVVFMLNLIEVIDVKYLNNIVEQSHRPIKSSIRMEIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5E2</accession>
    <name>D0Z5E2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000049</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000005">
        <property type="protein sequence ID" value="EEZ39064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39064">
        <property type="protein sequence ID" value="EEZ39064"/>
        <property type="gene ID" value="VDA_000049"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="101" mass="11856" checksum="388D064356909E4E" modified="2010-01-19" version="1">MAAQKALRFGGEKCTYFAACLKVVYRQIKLTHTESRQQYGDLMKRNNEYLSQLKERLSHYESKPDLLHREQTIADLLPRIKNAQIRQSYYVDLIFCAGVEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5G3</accession>
    <name>D0Z5G3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000006">
        <property type="protein sequence ID" value="EEZ39015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005307148.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000006.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39015">
        <property type="protein sequence ID" value="EEZ39015"/>
        <property type="gene ID" value="VDA_000070"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5032XWX">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="676054at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="369" mass="42895" checksum="89032040F53BFDD6" modified="2010-01-19" version="1">MERGLISFFEVNECGFYRIRNNKDSEHVEGSLTDSLALVEQWVKGRDFTQTVPWDVKCSPLRTQIYCKDIAVDPVTEDALFVLWKRYGDDSGKVKGISPDAKFGSNPEDSIKIDAKVKGQSAILGEPMYYWFIPKLNVVASINFPHSVASTTDVCNYIKRCIDLRISHPRKKVVEQRSFNQFANREQTIKRVNYKSEDGKFSMNYKFDVHMKELSSQQTNIKNLCKKITHIVVRDTISTVQEDQKDSCFRLFDLIQGKSLKKKFQKQVEIIEERRLSEEELESMLEVYHQEFKQTDTWNNLGFREDGNDTTRWFNKYVSKEHILMEPLDRNSNFHSAKSLLNELQKSRSDLLQTVISDNYEPVPVAVGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5G8</accession>
    <name>D0Z5G8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Conjugative transfer protein TrbE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000075</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TrbE/VirB4 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000006">
        <property type="protein sequence ID" value="EEZ39020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005307161.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000006.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000075"/>
    <dbReference type="EnsemblBacteria" id="EEZ39020">
        <property type="protein sequence ID" value="EEZ39020"/>
        <property type="gene ID" value="VDA_000075"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3451">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="182908at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018145">
        <property type="entry name" value="CagE_TrbE_VirB_cntrl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03135">
        <property type="entry name" value="CagE_TrbE_VirB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="2">
        <location>
            <begin position="455"/>
            <end position="700"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="800" mass="90120" checksum="93DF7AF006CF9A12" modified="2010-01-19" version="1">MFKLKSFREGIHGMSDLLNWAALVSDGTILNKDGAFSAGFLYQGIDVSSSSNTDRNDICMRVNNALRELGSGWMVQVDAIRTKSEAYVDKNSSYFTHPLLQLIDDSRRLYFESQGNKFTSTYILIVTYMPPSRRASKLADLVFEKGEKSKQINFAQRNLDRFNSAVDTLATRLESACHIERLRAYFDDTCQVWCDSFLSYLSYTVTGNWHPIALPPCPMALDSFIGSVDFLPGFTPRVDKEFISVITIDGFPSVAHPQYLAALDDLSIPYRWSTRFIFFDDFEAQKLLKTERKKWEQKVISFKDKLLNVADPKIDQAAASMVAQYQLAETAINKGESAYGQYSSTIILRHTDIDELNEQTEYVDKCIRYISGMHCRVETVNATDAFIGTLPSDSVANIRKPLLSVDNLVHLMPLNFIWTGNEFCPCPFYPSKSPPLLVASAQGSSVFRLNLHVDDLGHTLIFGPTGAGKSTLLATLAAQMNRYENAAIYAFDVGMSMYALSQCGGRHYDIGNDTSQFAPLSNLDTDFSWCNNFIEQLLVLQGLVIKPTHRTAIYNALMAMKGSNIKTLSEFRTQCQNEDVKSHIEYYTINGNGGDLLDGESDEFSLSSLSVFEIKSLMDRGDTDCAPVLSYIFRQIELRLKGEPAFILIDEGWISLKNEKFKNMLKDWLLTLRKLNCVVIFSTQLLSAAIESGILDVLMESCPTKIFLPNSEALNIKHTYKTFGLSNAQIKLIKEGTKKRDYYVVQGSSSRLIDLSLDDIAISVVGSSDKKSLLRIKELVKEHNENWYLYWLKEKGLDFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5H4</accession>
    <name>D0Z5H4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Conjugative transfer protein TrbI</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_000081</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TrbI/VirB10 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000006">
        <property type="protein sequence ID" value="EEZ39026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005307178.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000006.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000081"/>
    <dbReference type="EnsemblBacteria" id="EEZ39026">
        <property type="protein sequence ID" value="EEZ39026"/>
        <property type="gene ID" value="VDA_000081"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2948">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1674599at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16429">
        <property type="entry name" value="VirB10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005498">
        <property type="entry name" value="T4SS_VirB10/TraB/TrbI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042217">
        <property type="entry name" value="T4SS_VirB10/TrbI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03743">
        <property type="entry name" value="TrbI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="22"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="89"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ39026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="395" mass="42277" checksum="73BF1647C1C5B943" modified="2010-01-19" version="1">MDIKGSISGLGTGARKIANKKILAVISFILFFIVLVTMMVIAGKGQQKQSQAQSQEQTTQQNALDVDQSLNMSLASAPSENVIPSKQAIMEAKEEVAKKEEDLRQANDENSIENRLKEEAIKEYLVMRRAKSQALLAALKAPTHIEYEKTNSPNAANSTLDEAKAHLAALEKMRDGVSGTGNPKAETKSTLDGYLDNTRTALSSPYTLSIGTLIPATLGGALNSDIAGTVTATISQNVYDSATGSTLLFPQGAELVGQYNGQVAFGQERLPVQWYRINFPDGSTVNLRGMSGVDVEGQTGFEGDVNNHYWRLFGQSTLLGLIAGGTTAAISTNDNGDSVSPSQTIANGVIQQYSQVGTTLIQKNLQIAPTITVPSGYEFNIILTKDIVIPPYSTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-06-02" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVJ3</accession>
    <name>D0YVJ3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative inner membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_001573</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298306.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001573"/>
    <dbReference type="EnsemblBacteria" id="EEZ40547">
        <property type="protein sequence ID" value="EEZ40547"/>
        <property type="gene ID" value="VDA_001573"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2321">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1175086at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007343">
        <property type="entry name" value="Uncharacterised_pept_Zn_put"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30168">
        <property type="entry name" value="PTHR30168"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04228">
        <property type="entry name" value="Zn_peptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="287" mass="31338" checksum="6B715000EED8136D" modified="2010-01-19" version="1">MRWRDSKQSDNIEDRRGQEPAQAGMGGAGLIRLIPFLIRTKVGRIILLVGAAFFAVQHFTGGSLSGSQSPSKASSHVANDENKQFVAAVLGTTETVWKNHLGNRYQEPTLVLYNKVTRTGCGVGQAQTGPFYCPADQKIYLDLSFMKELKQLGAPGDFAFAYVIAHEVGHHVQNLLGTSTKVHQLQQRSSKVEANKLSVMLELQADCYAGVWGHDVNKQMNMLEPGDIEEGIKAADAVGDDRLQQMAGQAVQPDAFTHGSSAQRIAWFKKGFESGDPRVCDTFSSVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVK5</accession>
    <name>D0YVK5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nucleoid-associated protein VDA_001597</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001597</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 3">Cytoplasm</location>
            <location evidence="1 3">Nucleoid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the YejK family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298350.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001597"/>
    <dbReference type="EnsemblBacteria" id="EEZ40570">
        <property type="protein sequence ID" value="EEZ40570"/>
        <property type="gene ID" value="VDA_001597"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3081">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1368516at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009295">
        <property type="term" value="C:nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00730">
        <property type="entry name" value="NdpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007358">
        <property type="entry name" value="Nucleoid_associated_NdpA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38772">
        <property type="entry name" value="PTHR38772"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04245">
        <property type="entry name" value="NA37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="337" mass="38358" checksum="45B3F234FB235E32" modified="2010-01-19" version="1">MSLTLSNVILHQLAKNDQDELVVHLRDQALDDTPATQDFVAELHRVYSSKGAKGFAHFADDSEFSHWLKQYRNGEMNFLTFSNQSAERLKNELIKYPFAEAGTLVMTQYQSLATEYLFIGLLPTVHSMKVTEQLDISSTDYLDVSKMDIVARIDLSALASDPESKRYLTFIKGRVGRKIADFFLDFMQAEVGLDVKEQNQVLMQAVEDFCNDSRLDKEEKQQYRKQVYDYCNGQLQSGDEVTIKELSGELPTTDEGTDFYSFTSQQGYELEESFPADRTSMRKLTKFVGSGGGLTINFDAMLLGERIFYDPETDTLTIKGTPPNLKDQLNRRLNNDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVL1</accession>
    <name>D0YVL1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Gate domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001603</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001603"/>
    <dbReference type="EnsemblBacteria" id="EEZ40576">
        <property type="protein sequence ID" value="EEZ40576"/>
        <property type="gene ID" value="VDA_001603"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011642">
        <property type="entry name" value="Gate_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07670">
        <property type="entry name" value="Gate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="170"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="Gate" evidence="2">
        <location>
            <begin position="56"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="215" mass="22877" checksum="195443A12BEEEA39" modified="2010-01-19" version="1">MQSNQWYGVFDFTTLNGSFGSVVYSVNETADGIQTATTSLRGKGGSGARDGFLFALTLIPTVMFALGMINVLEHYGALDAARKLLTPLLRPLMGIPGNSGLALIASLQSTDAGAAMTRQLKDEGHLTKRETDVFTMFQFSAGATIVNFFSSGAVLFTLTYASGELAVTSSIGLAVAVMFVFKFVGANLFRIYLNITEGKEDKSNSNTPAPKEETA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVQ1</accession>
    <name>D0YVQ1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Poly(A) polymerase I</fullName>
            <shortName evidence="5">PAP I</shortName>
            <ecNumber evidence="5">2.7.7.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">pcnB</name>
        <name evidence="11" type="ORF">VDA_001216</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + RNA(n) = diphosphate + RNA(n)-3'-adenine ribonucleotide</text>
            <dbReference type="Rhea" id="RHEA:11332"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17347"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="ChEBI" id="CHEBI:173115"/>
            <dbReference type="EC" id="2.7.7.19"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.19" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001216"/>
    <dbReference type="EnsemblBacteria" id="EEZ40194">
        <property type="protein sequence ID" value="EEZ40194"/>
        <property type="gene ID" value="VDA_001216"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0617">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004652">
        <property type="term" value="F:polynucleotide adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006378">
        <property type="term" value="P:mRNA polyadenylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05398">
        <property type="entry name" value="NT_ClassII-CCAase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00957">
        <property type="entry name" value="PolyA_pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002646">
        <property type="entry name" value="PolA_pol_head_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010206">
        <property type="entry name" value="PolA_pol_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025866">
        <property type="entry name" value="PolyA_pol_arg_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032828">
        <property type="entry name" value="PolyA_RNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01743">
        <property type="entry name" value="PolyA_pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12626">
        <property type="entry name" value="PolyA_pol_arg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12627">
        <property type="entry name" value="PolyA_pol_RNAbd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01942">
        <property type="entry name" value="pcnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 5" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 5" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 5 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PolyA_pol" evidence="8">
        <location>
            <begin position="12"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="PolyA_pol_RNAbd" evidence="10">
        <location>
            <begin position="178"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="PolyA_pol_arg_C" evidence="9">
        <location>
            <begin position="296"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="75"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="397"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="30"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="32"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF12627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ40194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="430" mass="50143" checksum="CCC681C03DE83E3F" modified="2010-01-19" version="1">MLYRLNKAGFDAYLVGGGVRDLLLNKQPKDFDIATNATPEEIKALFRNCRLVGRRFRLAHILFGRDIIEVATFRGHHSDPQPLPKEKEAKQKQTSAQNQSGMLLRDNVYGTIDEDAERRDFTINALYYSVKDFTVTDYAHGVEDLDDGIIRLIGDPETRYREDPVRMLRAVRFAAKLDMNIERNTEAPIKQLAHLLQDIPAARLFEESLKLLQSGQGLATYHLLRQYNLFEQLFPLLGEHFTEDRSSQTELMLEHILQATDERIAEGKRINPAFMFAAMLWYPLMTRAEEITYASGLTFYDAFMVAANDILDEQVRSIAIPRRHTTTIRDIWMQQLRFSRRTGKRAFKMFEHPKFRAAFDFLEMRSHFEQDDIKELAKWWQDFQAADRFVRSKMVQAINDNGGNPQRRRPRRRPRRNNGPKKPQQTKTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVS6</accession>
    <name>D0YVS6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AGS_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001991</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299111.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40959">
        <property type="protein sequence ID" value="EEZ40959"/>
        <property type="gene ID" value="VDA_001991"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1746">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="796455at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05400">
        <property type="entry name" value="NT_2-5OAS_ClassI-CCAase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040511">
        <property type="entry name" value="AGS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006116">
        <property type="entry name" value="NT_2-5OAS_ClassI-CCAase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18134">
        <property type="entry name" value="AGS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AGS_C" evidence="1">
        <location>
            <begin position="297"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="421" mass="49117" checksum="02E7B863B69CFA49" modified="2010-01-19" version="1">MTVRRDFSLFLDNLKIKNKDSISSRYGTITKNLNEKFRGLENDKTNNSLQAGSYGRYSGIQGISDLDMLYILPPWAWNTYRKDPSKALDHAKDAIQQTYKTSKVRKDRNVVVVEMQDFTFEVVPVFEWQGVFKYPDTYNGGLWRKCNTRAELEAFRGLNTERKDNLRKLAKMVRAWKHRNDIQMSGFLIDTLCYNFFKDNTDYDKASFGSFDKMVRDFFQYLTKEPKKAYYYAFGSNSQVGVKKAFQADAEIALNNAIEAIEAREGGYEDKCNQRYKAIFGTKFPNREAKEVSAVNEQFIEELFDLDITNQIVIDCEIKSDLMTRMLSSLKFGGERIQHQRKLHFFVKQTDIGGDYEVKWKVRNRGYEADRQKNHRGDIMDDDGSKTRIETANFFGDHTVECYAIRDDRVIARHEITVPIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVV4</accession>
    <name>D0YVV4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tyr recombinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_002035</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299237.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002035"/>
    <dbReference type="EnsemblBacteria" id="EEZ41003">
        <property type="protein sequence ID" value="EEZ41003"/>
        <property type="gene ID" value="VDA_002035"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0582">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="785253at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038488">
        <property type="entry name" value="Integrase_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025166">
        <property type="entry name" value="Integrase_DNA_bind_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13356">
        <property type="entry name" value="Arm-DNA-bind_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0229">DNA integration</keyword>
    <keyword evidence="3" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyr recombinase" evidence="4">
        <location>
            <begin position="199"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="387" mass="44790" checksum="82F9DD568A8D9E73" modified="2010-01-19" version="1">MSLTDRQLNLISKQDTYDGKAEISDGEGLVVRITPQAKIYFHYRCRFNKKSLRIRIGKYPVTSLKEARRMHKLMMELRESGRNPNIAITGELEFITLDDCVAYWLKHYVPQLKEGTQALYRSFANNYLIGAFPERNVETIPAREWMQWLDTISLDKPKTANSLFTKLRSCLNFCKSKFIIEKTDLDRIKRQHVGKAPEVGTRVPTFSELSMIWLAIERSRASSSNKALHQLTMLWGNRLSELRLARRSHFDMEAGIWTVPKELSKTNTPIRRPIPTKARAILERVMATYDDVLFPGGDLDKPITISAANRYIRRIRDGLPIEDWRTHDFRRSLSTGASELGVMPHVVEKMLGHELGGVLSVYNKHDWLKEQLEGYELYAEKLDSYLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVW3</accession>
    <name>D0YVW3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001244</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297715.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40222">
        <property type="protein sequence ID" value="EEZ40222"/>
        <property type="gene ID" value="VDA_001244"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2968">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1825422at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007497">
        <property type="entry name" value="DUF541"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04402">
        <property type="entry name" value="SIMPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019830" evidence="1">
        <location>
            <begin position="23"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="242" mass="26346" checksum="C975D55485EEFB76" modified="2010-01-19" version="1">MKKTVLAAVLSMSSLLSINTMAADLSFPHLETQGSGEIVVQPDMAIFSVRVVETKATAKEAKEAADSAVAKFVERLTQVGVERSDINSANINLTPQYKYPKDAKPELTGYKASRQVTVTVHALDKLNTYLDDALGDGINRIDNIQLKVADETKYQEQARQAAIKDAISTAKSLAQGFGDSLDGVWQISYRNDYRPQPYMVNLGAAPRSAMADEAAVNASYNDASIKIRDEVNVIFKLKDGAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVW8</accession>
    <name>D0YVW8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">2-octaprenyl-6-methoxyphenol hydroxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_001249</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the UbiH/COQ6 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001249"/>
    <dbReference type="EnsemblBacteria" id="EEZ40227">
        <property type="protein sequence ID" value="EEZ40227"/>
        <property type="gene ID" value="VDA_001249"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0654">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008681">
        <property type="term" value="F:2-octaprenyl-6-methoxyphenol hydroxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016709">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018168">
        <property type="entry name" value="Ubi_Hdrlase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011295">
        <property type="entry name" value="UbiH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010971">
        <property type="entry name" value="UbiH/COQ6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01988">
        <property type="entry name" value="Ubi-OHases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01984">
        <property type="entry name" value="UbiH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01304">
        <property type="entry name" value="UBIH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="8">
        <location>
            <begin position="4"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ40227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="395" mass="43213" checksum="A74B9D31CBC95750" modified="2010-01-19" version="1">MKQFDVVIAGGAMTGATLAIALDKLSSQGLSVAVVEAVAPQLDQHPGFDSRAIALSYGSSEILQQLGMWAEIAPVATAIKDIHVSDRGHAGRVDMSAQEQGVDALGYVVELADIGQIFHHKLAQLSSITLYCPDSVAEIERDVQGCTITLSSGQQLRTQLLVAADGALSHCCDMVHIGRTEHDFDQLAVIANITTEQAHQGQAFERFTEFGPIALLPMSQGRSSLVWCINPEQQHQVMSWSDDDFLTQLQAAFGWRLGKLQHTGKRACYPLLLRQSGQITSHRVAVVGNAAQTLHPIAGQGFNLGIRDVISLAEEVAYQYRHHHDVGSQSVLSRYRQRRENDRQQTVMMTTGLVHLFANHYAPLVVGRNLGLMAMNAFHSLQAPLLRRAMGQVER</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW92</accession>
    <name>D0YW92_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 13 14">UDP-N-acetylmuramoylalanine--D-glutamate ligase</fullName>
            <ecNumber evidence="5 13 14">6.3.2.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">D-glutamic acid-adding enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">murD</name>
        <name evidence="17" type="ORF">VDA_001174</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13 14">Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13 14">
            <text>ATP + D-glutamate + UDP-N-acetyl-alpha-D-muramoyl-L-alanine = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</text>
            <dbReference type="Rhea" id="RHEA:16429"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29986"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83898"/>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 13 14">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 13 14">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the MurCDEF family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.9" evidence="5 13 14"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297572.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001174"/>
    <dbReference type="EnsemblBacteria" id="EEZ40152">
        <property type="protein sequence ID" value="EEZ40152"/>
        <property type="gene ID" value="VDA_001174"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0771">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1093223at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008764">
        <property type="term" value="F:UDP-N-acetylmuramoylalanine-D-glutamate ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00639">
        <property type="entry name" value="MurD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005762">
        <property type="entry name" value="MurD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01087">
        <property type="entry name" value="murD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11 13 14" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="8 13 14" id="KW-0132">Cell division</keyword>
    <keyword evidence="9 13 14" id="KW-0133">Cell shape</keyword>
    <keyword evidence="12 13 14" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13 17" id="KW-0436">Ligase</keyword>
    <keyword evidence="13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10 13 14" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase_M" evidence="16">
        <location>
            <begin position="113"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="15">
        <location>
            <begin position="302"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="115"/>
            <end position="121"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00015655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EEZ40152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="447" mass="47741" checksum="468D3C66D2201AD7" modified="2010-01-19" version="1">MKGLVDVNKVVVIGLGMTGLSVVNHLLRLPQSLDIKVIDTRNTPPGHDQLPADVELCCGQWNMEWLLAADLIVASPGIALATPELVTAAQAGVEIVGDIELFAREVTKPVVAITGSNGKSTVTSLVGEMAKEAGIDVGVGGNIGFAALDMLAQNHELYVLELSSFQLETTSSLHLAAAVYLNLSEDHMDRYQGLEDYSQAKMRIFHHANLAVYNRNDLATKPTDFTGAMTSFGFDDQDYGLVLIDDREWLAINQQPLMPADEIALVGRHNVANSLAALALADAAGIDREAACRALRRYTGLAHRCQLAVTKHGVRWVNDSKATNVASTEAALNGLNLAGKLHLLVGGDGKGADFSELKTVLADLNVQLYCFGRDGYQFAELVDNAILVETMAQAMELAASTAQSGDMILLSPACASWDQFANFMARGDAFIELATELQDKVAGAASC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWB1</accession>
    <name>D0YWB1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Type 4 fimbrial assembly protein PilC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">VDA_001189</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell inner membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the GSP F family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297600.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001189"/>
    <dbReference type="EnsemblBacteria" id="EEZ40167">
        <property type="protein sequence ID" value="EEZ40167"/>
        <property type="gene ID" value="VDA_001189"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1459">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1268170at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.81.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003004">
        <property type="entry name" value="GspF/PilC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001992">
        <property type="entry name" value="T2SS_GspF/T4SS_PilC_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018076">
        <property type="entry name" value="T2SS_GspF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042094">
        <property type="entry name" value="T2SS_GspF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30012">
        <property type="entry name" value="PTHR30012"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00482">
        <property type="entry name" value="T2SSF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00812">
        <property type="entry name" value="BCTERIALGSPF"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00874">
        <property type="entry name" value="T2SP_F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="174"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="222"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="380"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="10">
        <location>
            <begin position="74"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="10">
        <location>
            <begin position="277"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ40167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="408" mass="45042" checksum="62E8B25A715D3A6F" modified="2010-01-19" version="1">MAQLAANKIRYYRWRGVNQGGKKITGVTLGFQEQEVRAQLTEQMIQVKKIKRTNPSTLDKIRNQMKSSDVTAITRQLATMIESGVPIVQALKLMASSHHKAEVRAVLTQVNTQVEAGASLSKALKSSSPLFDNFYCDLVATGEETGYLGQVFVRLATYREKSEAMRKKVIKAMIYPSMVMLTAISVTILMLVFVIPQFAAIFGSFGAELPWFTRQVLKASDFLINYGGYLAVGLLLTLVLYRYSYKRSYSFRLRIARLSLRLPIIGNVILKATIARFARTLATTFSAGIPLLTGLQSAGKTAGNLHIEEAIMEAHTSAAAGMPLYLSLRQCNVFPELMLQMTMIGEESGSLDDMLNKMASLYENDVDNIVDNLGQILEPLIIIVLGVLIGGLLVAMYMPIFTLMSVIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWD6</accession>
    <name>D0YWD6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Membrane fusion protein of RND family multidrug efflux pump</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001406</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298013.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001406"/>
    <dbReference type="EnsemblBacteria" id="EEZ40381">
        <property type="protein sequence ID" value="EEZ40381"/>
        <property type="gene ID" value="VDA_001406"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0845">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1579676at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043602">
        <property type="entry name" value="CusB_dom_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00529">
        <property type="entry name" value="CusB_dom_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019843" evidence="2">
        <location>
            <begin position="19"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="4">
        <location>
            <begin position="66"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="domain" description="CusB_dom_1" evidence="3">
        <location>
            <begin position="294"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="398" mass="42735" checksum="66962BB2E3DACCE7" modified="2010-01-19" version="1">MRKPNISLRCVSLCVALALTGCNESNTGANPQAAMAGSAPKVSVVTMEPQSIQLSSALPGRTSAFKIAEVRPQVSGIILHRFFTEGSDVKEGDVLYQIDPATYKAAVNSAVAEVNKAKADASSAYKTEQRYADLVKRKLISQQDFDTAYSKWQQAKAQVGVAQANLDNAKIQLSYTKVKAPISGRIGLSEVTEGALVTANQANYLTTIQQLDPIYVDMTQSSTQMIKLKRGMANKLDDNGKLPVTVKLEDGSVYGHKGKLAFSGVTVDESTGSVTLRAIVPNPDNELLPGMFVRTQLPQPMAQTSLLVPQQSVERDQQGKAFVYVVNPQNQVERRAINVGQSIKSDWLVLSGLNAGDQVISRGLMRIKPGMKVAITADDTQAATTQTSAPSQAKVNHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWG7</accession>
    <name>D0YWG7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ribosomal RNA large subunit methyltransferase H</fullName>
            <ecNumber evidence="3">2.1.1.177</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">23S rRNA (pseudouridine1915-N3)-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">23S rRNA m3Psi1915 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">rRNA (pseudouridine-N3-)-methyltransferase RlmH</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rlmH</name>
        <name evidence="4" type="ORF">VDA_001426</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>pseudouridine(1915) in 23S rRNA + S-adenosyl-L-methionine = H(+) + N(3)-methylpseudouridine(1915) in 23S rRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42752"/>
            <dbReference type="Rhea" id="RHEA-COMP:10221"/>
            <dbReference type="Rhea" id="RHEA-COMP:10222"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:74486"/>
            <dbReference type="EC" id="2.1.1.177"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RNA methyltransferase RlmH family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.177" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001426"/>
    <dbReference type="EnsemblBacteria" id="EEZ40400">
        <property type="protein sequence ID" value="EEZ40400"/>
        <property type="gene ID" value="VDA_001426"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1576">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070038">
        <property type="term" value="F:rRNA (pseudouridine-N3-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd18081">
        <property type="entry name" value="RlmH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00658">
        <property type="entry name" value="23SrRNA_methyltr_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003742">
        <property type="entry name" value="RlmH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33603">
        <property type="entry name" value="PTHR33603"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02590">
        <property type="entry name" value="SPOUT_MTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004505">
        <property type="entry name" value="MT_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00246">
        <property type="entry name" value="tRNA_RlmH_YbeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="3">
        <location>
            <begin position="112"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="145" mass="16274" checksum="81531E4FC38278F5" modified="2010-01-19" version="1">MPKWVEEGYKEYSRRFPKDMPLELVEITAGKRGKNADIARILQKEGEAMLAAVPKGNRIVTLDIPGKRWDTEQLAEQLESWKLDGRDVSILIGGPEGLAPACKAAADQSWSLSPLTLPHPLVRVVMAESLYRAWSITANHPYHRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWR2</accession>
    <name>D0YWR2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">OmpR/PhoB-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001459</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298097.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001459"/>
    <dbReference type="EnsemblBacteria" id="EEZ40433">
        <property type="protein sequence ID" value="EEZ40433"/>
        <property type="gene ID" value="VDA_001459"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3710">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1653074at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="221" mass="25058" checksum="55503F80E1C25BDA" modified="2010-01-19" version="1">MIIYKHGNDFFEPQKSAYTADEITTKLSASETKILQYLIDNSGEIVSRETLLEIGWPEKIVVPNSLNVAIANLRKAFKTKNEIIITIKGAGFTVAKNTFVKQQQSINEEELQQEESEAIDLAQVTTSDTHTEINDRQEPPHNGVYIQRIRVNWQRACTGVLVLLAVLWMSLWLSSWQTPPCVAFENQKVCGNIELLKPEQLPKDKEGTLYIDMMGKIHAQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWU0</accession>
    <name>D0YWU0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RND multidrug efflux transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001486</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298141.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001486"/>
    <dbReference type="EnsemblBacteria" id="EEZ40460">
        <property type="protein sequence ID" value="EEZ40460"/>
        <property type="gene ID" value="VDA_001486"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0841">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="145346at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="334"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="360"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="386"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="431"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="463"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="526"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="853"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="879"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="905"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="954"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="980"/>
            <end position="1005"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="1040" mass="113545" checksum="5544F4F7F42F5543" modified="2010-01-19" version="1">MWLSDVSVKRPVVAVVLSLLLCVFGVVSFSKLAVREMPDIESPVVTVMTTYEGTSATVMESQVTTPIEDELSGISGIDNITSITRNGMSRITIEFDMDWDLTEGVSDVRDAVARAQRRLPDDANDPIVSKDNGSGEPALYINLSSSEMDRTQLTDYAQRVLEDRFSLINGVSSVSLSGGLYKVMYVKLKPELMAGRGVTTQDIVNALKDENVELPGGEVRNDQTVMSVRTARLYRNADDFKYLVVRTAADGTPVYLKDIADVAVGAENENSTFKSNGVVNLSLGIVTMSDANPLNVAKDVRMEVERMQKFLPQGTQLTLDYDATVFIERSIGEVYSTLFVTGALVVLVLYIFIGQARATLIPAITVPVSLVSAFIAAYFFGFSINLLTLMALILAIGLVVDDAIVVVENIFHHLQRGESPLLAAYKGTREVGFAVVATTAVLVMVFLPISFMEGMVGRLFTEFSVLLAMSVIFSSLIALTLTPVMGAKLLKANVKPTRFNQWINRQFDKLERGYRAIVTVAVKKRFMAPIVVIACVLASVGLMKVIPAQLAPQEDRGVLFAFVKGAEGTSYNRMIGNMDEVERRLLPMLGQGVLKSVSIQSPAFGGRAGDQTGFVIMQLEDWNDRTVSAQQALGMISKALAGIPDVMVRPMMPGFRGGSSEPVQFVLGGSDYTELFQWAQQLQTLAEDSPMMEGVDLDYAETTPELVVNIDRQRAAELGIPVAEIAKTLEVMLGGRSETTFVERGEEYDVYLRGDENSFNSSADLSQIYLRAKNGQLVTLDTVAKVEEVASAQKLSHNQKQKSITLKANLSEGYTLGEALDFLDQQSIELLPKDITIDYAGESKDFRENQSSIMMVFGLALLVAYLVLAAQFESFVNPLVVMLTVPMGIFGGLAGLWIMGQGLNIYSQIGMIMLIGMVTKNGILIVEFANQLRDKGTEFEQAIIDASVRRLRPILMTAFTTLFGALPLILSTGAGSESRIAVGTVVFFGMAFATLVTLLVIPAMYRLLSAKTKSPGYVEAQLEKELEQEYLGRMSQGNLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWV7</accession>
    <name>D0YWV7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 10">ATP-dependent Clp protease proteolytic subunit</fullName>
            <ecNumber evidence="5 8">3.4.21.92</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Endopeptidase Clp</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">clpP</name>
        <name evidence="11" type="ORF">VDA_001549</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 9">Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 10">Belongs to the peptidase S14 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.92" evidence="5 8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298256.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001549"/>
    <dbReference type="MEROPS" id="S14.001"/>
    <dbReference type="EnsemblBacteria" id="EEZ40523">
        <property type="protein sequence ID" value="EEZ40523"/>
        <property type="gene ID" value="VDA_001549"/>
    </dbReference>
    <dbReference type="GeneID" id="57342393"/>
    <dbReference type="eggNOG" id="COG0740">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1728970at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07017">
        <property type="entry name" value="S14_ClpP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00444">
        <property type="entry name" value="ClpP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001907">
        <property type="entry name" value="ClpP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023562">
        <property type="entry name" value="ClpP/TepA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033135">
        <property type="entry name" value="ClpP_His_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018215">
        <property type="entry name" value="ClpP_Ser_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10381">
        <property type="entry name" value="PTHR10381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00574">
        <property type="entry name" value="CLP_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00127">
        <property type="entry name" value="CLPPROTEASEP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00493">
        <property type="entry name" value="clpP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00382">
        <property type="entry name" value="CLP_PROTEASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00381">
        <property type="entry name" value="CLP_PROTEASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5 8" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 8" id="KW-0720">Serine protease</keyword>
    <feature type="active site" evidence="6">
        <location>
            <position position="111"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="111"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 7">
        <location>
            <position position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ40523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="207" mass="22931" checksum="F7E7F0DB254E648F" modified="2010-01-19" version="1">MSYQEKNAMSPILDALVPMVVEQTSRGERSYDIYSRLLKERVIFLTGQVEDHMANLVVAQLLFLESENPDKDIYLYINSPGGSVTAGMSIYDTMQFIKPNVSTVCMGQACSMGAFLLAGGAKGKRYCLPNSRVMIHQPLGGFQGQASDIQIHAQEILTIKQKLNNLLAEHTGQPLEVIERDTDRDNFMSADQAVEYGLVDAVLSHRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX13</accession>
    <name>D0YX13_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002061</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299314.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002061"/>
    <dbReference type="EnsemblBacteria" id="EEZ41029">
        <property type="protein sequence ID" value="EEZ41029"/>
        <property type="gene ID" value="VDA_002061"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031N6R">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1518368at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="189" mass="22021" checksum="26CDFC5FE25ECB97" modified="2010-01-19" version="1">MEKSSVLPFFHRSGDHKLNIKTISLGDFRKLPYVMKDELSSPEQFKQFKAMILACTDLTELEFEELSAPDFTQLHQDIRAFILTPSDELNDQPLTGTQFEFDLLFPFKNELNEDIGHIKFKVPKVKHSEALANIDDHYEREEFMFRVVCDLEKQDMDMMAINDYLAIKPQVGAFFQLAGDYFRPKTSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX78</accession>
    <name>D0YX78_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Fructose repressor FruR LacI family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001937</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298973.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001937"/>
    <dbReference type="EnsemblBacteria" id="EEZ40905">
        <property type="protein sequence ID" value="EEZ40905"/>
        <property type="gene ID" value="VDA_001937"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1796334at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009750">
        <property type="term" value="P:response to fructose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012781">
        <property type="entry name" value="Fruct_sucro_rep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001761">
        <property type="entry name" value="Peripla_BP/Lac1_sug-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00532">
        <property type="entry name" value="Peripla_BP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02417">
        <property type="entry name" value="fruct_sucro_rep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="326" mass="36213" checksum="0B61BB4AFB6A9370" modified="2010-01-19" version="1">MTLDEIAKLAGVSRTTASYVINGKAQKYRISEKTQQKVMAVVNEHNFRPDHAASSLRAGSSRSFGLIIPDLENTSYAKIAKLLERDARRAGYQLIIACSDDDGETEMKVAENLISRRIDALIVATVLPPDTPFYQQLQQKNVPIIAIDRPLTDEHFASVISEDLMGAYELTKAVMDKSIKTVGLIGAMKELGVSKEREQGFISAAQLYSDATITLAYGKQFSRTEGKKLVTDWVNTDTVPEVILATSYTLFEGVLDCLLLYPEHFKHVKLATFGDNRLLDFLPIKVQSLSQQFEVIAETALELALNASAKRYQAGVEVVPRKLLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX85</accession>
    <name>D0YX85_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_001944</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S66 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001944"/>
    <dbReference type="EnsemblBacteria" id="EEZ40912">
        <property type="protein sequence ID" value="EEZ40912"/>
        <property type="gene ID" value="VDA_001944"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1619">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027461">
        <property type="entry name" value="Carboxypeptidase_A_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027478">
        <property type="entry name" value="LdcA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040449">
        <property type="entry name" value="Peptidase_S66_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040921">
        <property type="entry name" value="Peptidase_S66C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003507">
        <property type="entry name" value="S66_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30237">
        <property type="entry name" value="PTHR30237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02016">
        <property type="entry name" value="Peptidase_S66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17676">
        <property type="entry name" value="Peptidase_S66C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028757">
        <property type="entry name" value="LD-carboxypeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141986">
        <property type="entry name" value="SSF141986"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018649" evidence="4">
        <location>
            <begin position="18"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S66" evidence="5">
        <location>
            <begin position="23"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S66C" evidence="6">
        <location>
            <begin position="190"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="123"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="3">
        <location>
            <position position="220"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="3">
        <location>
            <position position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR028757-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF17676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="314" mass="35303" checksum="3174779694998B7B" modified="2010-01-19" version="1">MLKALIFAMLVPITAFASNINNVALVSSSTQFDDSQLPQIQQNLEQKGYSVSLQYLDQVISDFGYVNTDQKRAKDLIRALTDDNIDILWFVRGGGGALNLLPYLEQHKDELKSAKPKVLVGFSDVTALHHFVNQELGWPSIHGVTAATNLEMGSFNQEPLPNISELLKNGVEYDYVLPLNDLAKTAKVNGTLVGGNHTLVAATFGTKYSYDFKNKVLLLEDVGVSFRQLDRLLQQILFLNQFDVNAVIFGQYYPADPTDPERLMYKTVLERFAQQLNKPVYYFPFIGHGKYNRPVILGHSVELSCKEEYCNLTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX94</accession>
    <name>D0YX94_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001953</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299004.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001953"/>
    <dbReference type="EnsemblBacteria" id="EEZ40921">
        <property type="protein sequence ID" value="EEZ40921"/>
        <property type="gene ID" value="VDA_001953"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0488">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1112046at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032781">
        <property type="entry name" value="ABC_tran_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12848">
        <property type="entry name" value="ABC_tran_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="320"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="352"/>
            <end position="359"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="531" mass="59638" checksum="43E35BC1C84D2128" modified="2010-01-19" version="1">MISTANITMQFGEKPLFENISVKFGEGNRYGLIGANGCGKSTFMKILGGELEPSSGTVSKDPNERMAKLGQDQFAFEEYTVVDTVIMGHKELWKVKEERDRIYAMPEMSEDDGMRVADLEVEFAEMDGYSAEARAGELLLGLGIPEDLHFGLMSAVAPGLKVRVLLAQVLFANPEIMLLDEPTNNLDIHTIAWLEQVLLERNCTMIIISHDRHFLNSVCTHMADLDYGELRLFPGNYDEYMIAAESARDRLLADNAKKKAQMAELQTFVSRFSANASKAKQATSRQKQLDKIQLDEVKASSRQSPFIRFEQEKELFRNALEVEGLKQGYGDNILINGVRLLVEVGERIAIIGENGIGKSTFLNTLAGAMEPMEGMVKWSENSNIGFYAQDHGADFEEDLNLMDWMSQWKKEGDDEQVVRGILGRMLFSQHDIKKSVKVLSGGEQGRMLFGKLIMQKPNILLMDEPTNHMDMESIEALNLALEHFKGTLMFVSHDRQFVSSIATRIIEITKDGVEDFHGTYDEYLAKKGLEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXE8</accession>
    <name>D0YXE8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">GTP 3',8-cyclase</fullName>
            <ecNumber evidence="9">4.1.99.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Molybdenum cofactor biosynthesis protein A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">moaA</name>
        <name evidence="11" type="ORF">VDA_001627</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>AH2 + GTP + S-adenosyl-L-methionine = (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate + 5'-deoxyadenosine + A + H(+) + L-methionine</text>
            <dbReference type="Rhea" id="RHEA:49576"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:131766"/>
            <dbReference type="EC" id="4.1.99.22"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="9">Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.</text>
    </comment>
    <comment type="pathway">
        <text evidence="9">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Monomer and homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the radical SAM superfamily. MoaA family.</text>
    </comment>
    <dbReference type="EC" id="4.1.99.22" evidence="9"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298401.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001627"/>
    <dbReference type="EnsemblBacteria" id="EEZ40600">
        <property type="protein sequence ID" value="EEZ40600"/>
        <property type="gene ID" value="VDA_001627"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2896">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1199289at2"/>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019008">
        <property type="term" value="C:molybdopterin synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061798">
        <property type="term" value="F:GTP 3',8'-cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904047">
        <property type="term" value="F:S-adenosyl-L-methionine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01225_B">
        <property type="entry name" value="MoaA_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013483">
        <property type="entry name" value="MoaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010505">
        <property type="entry name" value="Mob_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06463">
        <property type="entry name" value="Mob_synth_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02666">
        <property type="entry name" value="moaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6 9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 9" id="KW-0408">Iron</keyword>
    <keyword evidence="5 9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="3 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="10">
        <location>
            <begin position="8"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="17"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="24"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="28"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="256"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-substrate</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="259"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-substrate</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="261"/>
            <end position="263"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="273"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-substrate</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ40600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="328" mass="37087" checksum="63923AED99E023BB" modified="2010-01-19" version="1">MAKQFEDSFHRKFYYLRLSVTDVCNFKCTYCLPDGYKPEEKKPSFLTVDEIRRVTSAFAECGTSKVRITGGEPSLRRDFTDIIHTVASQPGIEKVAMTTNGYRMAKHVQSWRDAGLTNINVSVDSLDPKMFHQITGENMFHQVMQGIDAAFDVGFEQVKINTVLLRDLNSQELPKFLEWIKTRPIQLRFIELMQTGEMDNLFTNHHVSGVSIRNHLIANGWLLKVKSANDGPAQVFCHPDYMGEIGLIMPYEKNFCQSCNRLRVSAKGKLHLCLFGEEGVDLRDLLQQDEQQGELISRIQAGLQNKAVGHFLDEGKTGMTPHLASIGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXI4</accession>
    <name>D0YXI4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Endolytic murein transglycosylase</fullName>
            <ecNumber evidence="7">4.2.2.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Peptidoglycan polymerization terminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">mltG</name>
        <name evidence="8" type="ORF">VDA_001690</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the transglycosylase MltG family.</text>
    </comment>
    <dbReference type="EC" id="4.2.2.-" evidence="7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298522.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001690"/>
    <dbReference type="EnsemblBacteria" id="EEZ40661">
        <property type="protein sequence ID" value="EEZ40661"/>
        <property type="gene ID" value="VDA_001690"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1559">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="708179at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008932">
        <property type="term" value="F:lytic endotransglycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd08010">
        <property type="entry name" value="MltG_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02065">
        <property type="entry name" value="MltG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003770">
        <property type="entry name" value="MLTG-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30518">
        <property type="entry name" value="PTHR30518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02618">
        <property type="entry name" value="YceG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00247">
        <property type="entry name" value="TIGR00247"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1 7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="5 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="site" description="Important for catalytic activity" evidence="7">
        <location>
            <position position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ40661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="337" mass="37902" checksum="C71AC33A278EEC3B" modified="2010-01-19" version="1">MLKKLMIVIVLLGVIAAGGVVFAYQEVMASLSQPVTTEQKELITVKPGTSFRSLLNQLEKQDIIPASQWYRWIGHVEPELLQLKAGSYLVESKMTLQQLLTLIGSGKEHQFSITLVEGERFSEWLKELQQAPEMQHETVGLSEAEIAKALNIDTNKLEGYMLPETYNYTAGMSDLDILKRAHNKLESVLENAWQGREKDLPLKTPYDVLIMASIIEKETAVDSERDVVSSVFTNRLEKGMRLQTDPTVIYGMGDKYDGNIRKRDLTTPTPYNTYVIFGLPPTPIAMPSKASILAAVHPAQTQYLYFVANGKGGHTFSKTLAEHNRAVRQYLRTLRNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXI9</accession>
    <name>D0YXI9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PTS system glucose-specific EIICB component</fullName>
            <ecNumber evidence="3">2.7.1.199</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">EIICB-Glc</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">VDA_001695</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-glucose(out) + N(pros)-phospho-L-histidyl-[protein] = D-glucose 6-phosphate(in) + L-histidyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:33367"/>
            <dbReference type="Rhea" id="RHEA-COMP:9745"/>
            <dbReference type="Rhea" id="RHEA-COMP:9746"/>
            <dbReference type="ChEBI" id="CHEBI:4167"/>
            <dbReference type="ChEBI" id="CHEBI:29979"/>
            <dbReference type="ChEBI" id="CHEBI:61548"/>
            <dbReference type="ChEBI" id="CHEBI:64837"/>
            <dbReference type="EC" id="2.7.1.199"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.7.1.199" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298530.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001695"/>
    <dbReference type="EnsemblBacteria" id="EEZ40666">
        <property type="protein sequence ID" value="EEZ40666"/>
        <property type="gene ID" value="VDA_001695"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1263">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1264">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2035550at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005355">
        <property type="term" value="F:glucose transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008982">
        <property type="term" value="F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00212">
        <property type="entry name" value="PTS_IIB_glc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036878">
        <property type="entry name" value="Glu_permease_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018113">
        <property type="entry name" value="PTrfase_EIIB_Cys"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003352">
        <property type="entry name" value="PTS_EIIC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013013">
        <property type="entry name" value="PTS_EIIC_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001996">
        <property type="entry name" value="PTS_IIB_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011299">
        <property type="entry name" value="PTS_IIBC_glc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00367">
        <property type="entry name" value="PTS_EIIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02378">
        <property type="entry name" value="PTS_EIIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55604">
        <property type="entry name" value="SSF55604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00826">
        <property type="entry name" value="EIIB_glc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02002">
        <property type="entry name" value="PTS-II-BC-glcB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51098">
        <property type="entry name" value="PTS_EIIB_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01035">
        <property type="entry name" value="PTS_EIIB_TYPE_1_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51103">
        <property type="entry name" value="PTS_EIIC_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0418">Kinase</keyword>
    <keyword evidence="13 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0598">Phosphotransferase system</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="8 19" id="KW-0808">Transferase</keyword>
    <keyword evidence="10 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="47"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="78"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="105"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="143"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="252"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="300"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="353"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="domain" description="PTS EIIC type-1" evidence="18">
        <location>
            <begin position="3"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="PTS EIIB type-1" evidence="17">
        <location>
            <begin position="398"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphocysteine intermediate; for EIIB activity" evidence="15">
        <location>
            <position position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00032303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EEZ40666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="476" mass="50393" checksum="CCF07D89DFC10FF9" modified="2010-01-19" version="1">MFKNLFASLQKVGKALMLPVSVLPVAGILLGVGAANFSWLPDIVSQVMAQAGGSVFGQMPLLFAVGVALGFTNNDGVAGLAAIVGYGIMAATLGVMAQVMGVDKIDTGVLGGILTGGIAAWAFNKFFRIQLPDYLGFFAGKRFVPIMTGFCAIALALVLSVVWQPVGAGIAAFSDWAAHQNPTVAFGIYGIIERSLIPFGLHHVWNVPFFFEAGSCVNAAGEARTGILTCYLEANEATRLAGNGFGQLAGGYMFKMFGLPAAAIAIWHCAKPENKAKVGGIMISAALTSFLTGITEPIEFSFMFVAPILYVIHAFLAGSAYVLTNLLGMVHGTSFSHGFIDFVVLSANSQKLWLFPVMGIIYAIIYYVVFRVVITKLDLKTPGREDEDTSAAVTGSESEMAQELVTAFGGKDNITNLDACITRLRVSVADVNKVDQDRLKKLGAAGVVVAGSGVQAIFGTKSDNLKSDMDEWIRSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXK8</accession>
    <name>D0YXK8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Dipeptidase</fullName>
            <ecNumber evidence="4">3.4.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_001723</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>an L-aminoacyl-L-amino acid + H2O = 2 an L-alpha-amino acid</text>
            <dbReference type="Rhea" id="RHEA:48940"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:59869"/>
            <dbReference type="ChEBI" id="CHEBI:77460"/>
            <dbReference type="EC" id="3.4.13.19"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the peptidase C69 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298581.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001723"/>
    <dbReference type="MEROPS" id="C69.001"/>
    <dbReference type="EnsemblBacteria" id="EEZ40693">
        <property type="protein sequence ID" value="EEZ40693"/>
        <property type="gene ID" value="VDA_001723"/>
    </dbReference>
    <dbReference type="GeneID" id="57342192"/>
    <dbReference type="eggNOG" id="COG4690">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="414486at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070004">
        <property type="term" value="F:cysteine-type exopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016805">
        <property type="term" value="F:dipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005322">
        <property type="entry name" value="Peptidase_C69"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12994">
        <property type="entry name" value="PTHR12994"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03577">
        <property type="entry name" value="Peptidase_C69"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0224">Dipeptidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019869" description="Dipeptidase" evidence="5">
        <location>
            <begin position="25"/>
            <end position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="491" mass="54982" checksum="93F1405EB9D418BF" modified="2010-01-19" version="1">MNQKFTITVLSAAIFASVSLSASACTGILVGKQASADGSIMIARNEDFGVNNWNKHLAYRPAQTNQAGDWQLGNGLVVPMPPSFYAYSAIPDWDAATMNPDGRYYEERGINEYNVAISATTSAEVNEKAQAADPLVKQGVIEANIPTLILPQVKTAKQGVELLGQYIEKYGAGEGNSLYLADVNEAWLFEVGSGHQWIAVKVPDDSYAMMANGLRIHGVDLNSPDVLHSPTLVEFVTQHKLLDNPDPKSFNFAKAFGVIGDVYNTDREWLGQEMLTPSFKQKTRQQQYPLFLKPDQKITVAQIDKVLSSTYAGTELEQKGERPIRVDRQLESHIIALRPDMPKPFQGLIWQSYGVLAESVLVPLYSSLHSYPQPYTVGTDTYSDDSAYWQFRSLTALASTNTDKYLPALHQLWQDKETKLYKQVSALDNVLQQTYKMDPQAALDMASDYSYSQLQQTYSMAKQMRYKMMTDLTKSTEKKYSEEEFKKIMSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXL7</accession>
    <name>D0YXL7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 16">Phospholipase A1</fullName>
            <ecNumber evidence="6 16">3.1.1.32</ecNumber>
            <ecNumber evidence="7 16">3.1.1.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Phosphatidylcholine 1-acylhydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">VDA_001758</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 16">
            <text>a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1-acyl-sn-glycero-3-phosphocholine + a fatty acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15801"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
            <dbReference type="ChEBI" id="CHEBI:57643"/>
            <dbReference type="ChEBI" id="CHEBI:58168"/>
            <dbReference type="EC" id="3.1.1.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 16">
            <text>a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 2-acyl-sn-glycero-3-phosphocholine + a fatty acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18689"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
            <dbReference type="ChEBI" id="CHEBI:57643"/>
            <dbReference type="ChEBI" id="CHEBI:57875"/>
            <dbReference type="EC" id="3.1.1.32"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="16">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="16">Binds 1 Ca(2+) ion per monomer. In the dimeric form the Ca(2+) is bound by different amino acids with binding of each Ca(2+) shared with ligands coming from each monomer. The Ca(2+) ion may have a role in catalysis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 16">Homodimer; dimerization is reversible, and the dimeric form is the active one.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="16">Cell outer membrane</location>
            <topology evidence="16">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <text evidence="16">One of the very few enzymes located there.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 16">Belongs to the phospholipase A1 family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.32" evidence="6 16"/>
    <dbReference type="EC" id="3.1.1.4" evidence="7 16"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298640.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001758"/>
    <dbReference type="EnsemblBacteria" id="EEZ40726">
        <property type="protein sequence ID" value="EEZ40726"/>
        <property type="gene ID" value="VDA_001758"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2829">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1546598at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052740">
        <property type="term" value="F:1-acyl-2-lysophosphatidylserine acylhydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052739">
        <property type="term" value="F:phosphatidylserine 1-acylhydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008970">
        <property type="term" value="F:phospholipase A1 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004623">
        <property type="term" value="F:phospholipase A2 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00541">
        <property type="entry name" value="OMPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003187">
        <property type="entry name" value="PLipase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036541">
        <property type="entry name" value="PLipase_A1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40457">
        <property type="entry name" value="PTHR40457"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02253">
        <property type="entry name" value="PLA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01486">
        <property type="entry name" value="PHPHLIPASEA1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56931">
        <property type="entry name" value="SSF56931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="16" id="KW-0106">Calcium</keyword>
    <keyword evidence="15 16" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="13 16 17" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="16" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="16" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="11 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12 16" id="KW-0732">Signal</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1134">Transmembrane beta strand</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019613078" description="Phospholipase A1" evidence="16">
        <location>
            <begin position="21"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00021726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU366027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EEZ40726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="330" mass="38265" checksum="3814F64E00DD3C57" modified="2010-01-19" version="1">MVKRTLLLLSFAPLAMPTYAADELSAFDSCLLDAVKNQSGKLTVDTIRKRCQESIEQAPAPTNLVSNRIENERDTAFNPFVITPHRMNYILPVTYTDHINRGAYDKTDWAGHLKNTEAKFQISFKVPLNYDDMFIDGDGLFFAFTMKSYWQVYAGDISRPFRETNYRPELFYFAPTPWQPLGGKTWMTFGIEHQSNGRSQVLSRSWNRIYTNFIYEKDNFALSFQPWYRLPEDDKRYPGDPEGDDNPDIADYMGHFELTTVYKWDDYEFSFLGRQNFSTHKGYGEFGVTFPLWGRLRGYAQYTTGYGDSMIDYNINQNRIGLGVALTDLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXQ2</accession>
    <name>D0YXQ2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Membrane-associated phospholipid phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001751</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001751"/>
    <dbReference type="EnsemblBacteria" id="EEZ40719">
        <property type="protein sequence ID" value="EEZ40719"/>
        <property type="gene ID" value="VDA_001751"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0494">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0671">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="P_Acid_Pase_2/haloperoxi_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="P_Acid_Pase_2/haloperoxidase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00014">
        <property type="entry name" value="acidPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="SSF48317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="231"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="258"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="298"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="328"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="358"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="390"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="413"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="441"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="469"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="domain" description="Nudix hydrolase" evidence="2">
        <location>
            <begin position="37"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="506" mass="56706" checksum="02C7CFB31EB47467" modified="2010-01-19" version="1">MHNIIGQRILLLFFILVSLTFGSIGSAWASSTTSEVPEGIVGAVCVIRHDNKVVMISEVITEKLALPGGYIDSGYNAPQTAIREALEETGLHVHVDKFLQYRGRAAIYACVANDPIPVTEFKTKSGFTAVASWSSAHFGKEVKQVYLINPFKVDGKNYRYPDDIVLLKKWLQQTPNSAVTYYHNLSQEVNPLHRWELSQMLTFQHWVDGLSSWQQTLFSSWMTVTNLPGEYGFIFTVLFGCLIAFGPVSFLRLSTVMLSVTMVASIIKLTIASPRPFYIIPALQKVAASGYGFPSGHTLMALVLWGFIGIQAYRYIKVHNPSAQLMRWRLGIMSIVVLFSLSQAVARVWYGVHFISDTVASLVIGSVMIAGFTLWINLDKHNLTRCMTNKWFWLNVTVAFGLIAGTTQAPDHIYLFSCVLTIFLINDYVPRQYQRLNLRYLLGLITCLLIGCSVILYSGYMLINLSNVSLIVLAIRSITIVVLITWILGCSSWFYRQTCPPLAHAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXS5</accession>
    <name>D0YXS5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Endopeptidase La</fullName>
            <ecNumber evidence="1">3.4.21.53</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002088</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of proteins in presence of ATP.</text>
            <dbReference type="EC" id="3.4.21.53"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S16 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.53" evidence="1"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299396.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002088"/>
    <dbReference type="MEROPS" id="S16.A10"/>
    <dbReference type="EnsemblBacteria" id="EEZ41056">
        <property type="protein sequence ID" value="EEZ41056"/>
        <property type="gene ID" value="VDA_002088"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1067">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="128102at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041699">
        <property type="entry name" value="AAA_32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008269">
        <property type="entry name" value="Lon_proteolytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027065">
        <property type="entry name" value="Lon_Prtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10046">
        <property type="entry name" value="PTHR10046"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13654">
        <property type="entry name" value="AAA_32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05362">
        <property type="entry name" value="Lon_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51786">
        <property type="entry name" value="LON_PROTEOLYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Lon proteolytic" evidence="2">
        <location>
            <begin position="334"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="426"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="580" mass="64495" checksum="B033F54B3B62792A" modified="2010-01-19" version="1">MHEESWRTLIPDYTPYRNVLENYNELAPADTGLLQPRLADAVRRFTAITIQPRVLRVTAPDNKIYRDYVIELLTKYEQERIQKQTSQQSLEQSSITDPIVVTSEYVTEQSLFGTVYPPSSDAKVVTYNVKHGLIHQANNGYLVLSVGALIANPGAWSRLKSVLMNGELEWQPSEPKKAYPLPTAEKLNVKLVLVGDRFLMADLDEAEPDLSAGFAMYGEFEQDLLLTEQSLPDYLRYVKAIAKRSQLPDLADSDAVEALLSAGARYAEDQSRVPLCLLWHTNVLSEASIESENQQITREHLKASLNAKLYRESYLPERAIADIHHGQVVIECQGQEVGQVNGLTVVEMPGHPMSYGEPARISCVVHFGDGDISDVERKVELGGNIHAKGMMIMQAFLSTALNLDQALPFSASIVFEQSYSEVDGDSASLAELCALVSALSVQPINQEIAVTGAVDQFGRVQAVGGVNEKIEGFYKVCVHRGLTGNQGVILPKTNLSSLCLNDEVIEAIKSGQFHIWTVENVDEAIPRLMGQTFRGKEDDTDTILAKIAERIELFHLGGMYPEENIFSRIRNTIQNWFVQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXT2</accession>
    <name>D0YXT2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002095</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299419.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002095"/>
    <dbReference type="EnsemblBacteria" id="EEZ41063">
        <property type="protein sequence ID" value="EEZ41063"/>
        <property type="gene ID" value="VDA_002095"/>
    </dbReference>
    <dbReference type="GeneID" id="57341781"/>
    <dbReference type="eggNOG" id="COG3287">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1942718at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019494">
        <property type="entry name" value="FIST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013702">
        <property type="entry name" value="FIST_domain_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08495">
        <property type="entry name" value="FIST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10442">
        <property type="entry name" value="FIST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00897">
        <property type="entry name" value="FIST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01204">
        <property type="entry name" value="FIST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FIST" evidence="1">
        <location>
            <begin position="30"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="FIST_C" evidence="2">
        <location>
            <begin position="226"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="391" mass="42475" checksum="011AD445604E46D0" modified="2010-01-19" version="1">MDIATSFSSHSDTNLAIREAIDSLTTKVFKPQLVLAYFSEHYDVVLLRNALSEEYPDAQILACSSCQGIMTDEGYISDQGIALWSVSDHYGAYGSAIVSTNQSPKDMARQAVLRAIENSGRPGELPALILLHATPGHEEEVISGIESEVGGAVPIIGGSAADDLVAGQWNLFTHHQIAQKGVGIVVFYPSCQVSYSFHSGYASSGLSAIATRVEGREVIELDGRPAMDVYQEWLGKTLAINDSIVSESSLNPLGRIAGTVHDLPYFKLAHPLRVTEQRGIELFAQVNEGEVLYFMEGTVERLVTRAGRVINSAYDISRSNRLDPIGGITIYCAGCMLKVKDRMKDVAKYVNIAMHNAPFVCPFTFGEQGQFVGGENAHGNLMISAVLFHRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXZ5</accession>
    <name>D0YXZ5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Histidine kinase</fullName>
            <ecNumber evidence="3">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">VDA_002158</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299561.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002158"/>
    <dbReference type="EnsemblBacteria" id="EEZ41126">
        <property type="protein sequence ID" value="EEZ41126"/>
        <property type="gene ID" value="VDA_002158"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4191">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033463">
        <property type="entry name" value="sCache_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029151">
        <property type="entry name" value="Sensor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17202">
        <property type="entry name" value="sCache_3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103190">
        <property type="entry name" value="SSF103190"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="20"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="10">
        <location>
            <begin position="453"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="389"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ41126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="681" mass="77638" checksum="FB473D4F02185340" modified="2010-01-19" version="1">MKLRTFVATWLNRFRTMVRYRLLVLTSVPIFLTMLALIGITLYWTLMYTWQSALMNVRADLAVAHHSMELLQREQWMQLTSLTHSYDFQQRLRHDERSLTRWVPTQAKNYDLDFVIIHPASQLAEFPKSNRKLLLAGKQQTFFEVLNSQELYRLNPDLPARAQIPMLRGNKIERRGLVSRSLIPIFNDRHELQWIIDGGMLLNNSTQLVDRIRDLVYASNTLPKGSIGTVTLFMDDLRVSTNVPLDSSMKKGRAIGTPVSEQVKLDVLKDGQVWVDRAYVYDAWYVSAYEPLRNYDGKVIGMLYTGYLEWPLVRTYLTNIIEMGIAICIVLLLSSIIVYRGSRDLFLPIEKIHHVVRAVQLGLKKRIGKLDLSENHELQILGRQFDSMLDLLDQRNEAIKQAAIELEDKVDARTHSLHEKTEELERHIQLLNQARHKLVNSEKLAALGELTAGIAHEINNPIAVILGNVELIQFELGDGTAPIKDELEAIHEQIDRIRNITRSLLQYSRQGGVQDEIIWQHINPIVEESLTLVRSGTKKLDIKIETDLQAKCSVEVNRHQLLQVLVNLQMNGVHAMNDSGILQISTQDWTEGKTTIGAIIKITDHGCGISEQNLTRIFNPFFTTRRSGTGLGLSVSQGIIESIGGEIRVQSEVEVGTTFSIFLHEKAMIEQEGDILLQIKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXZ7</accession>
    <name>D0YXZ7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ABC-type tungstate transport system binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002160</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002160"/>
    <dbReference type="EnsemblBacteria" id="EEZ41128">
        <property type="protein sequence ID" value="EEZ41128"/>
        <property type="gene ID" value="VDA_002160"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2998">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024370">
        <property type="entry name" value="PBP_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12849">
        <property type="entry name" value="PBP_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018673" evidence="1">
        <location>
            <begin position="22"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="PBP_domain" evidence="2">
        <location>
            <begin position="27"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="274" mass="30139" checksum="E80CFB0F3CBBE0C4" modified="2010-01-19" version="1">MKLLKTALVILGFAATSMAHAADTTKENKTIRLATTTSTYHSGLLDYLLPEFKKDTGYSVDVLAAGTGKALRMGENGDVDLVMTHAPKAEATFVDKGFGVLPRKLMHNDFILVGPEKDPAKIKGDKNIVDALTKIASYNATFISRGDDSGTNKKELNLWAQAKMEPNFGGYKAVGQGMGPTLNMASELQAYTLTDRGTWLAYQNKLHLGIMVQGDKRLFNPYQVILVNPSRYPTINYQGAKVFSDWLVNPKAQTMINDYKRHGEQLFVADAITK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY27</accession>
    <name>D0YY27_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Bcr/CflA family efflux transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_002190</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell inner membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Bcr/CmlA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002190"/>
    <dbReference type="EnsemblBacteria" id="EEZ41158">
        <property type="protein sequence ID" value="EEZ41158"/>
        <property type="gene ID" value="VDA_002190"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990961">
        <property type="term" value="P:xenobiotic detoxification by transmembrane export across the plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004812">
        <property type="entry name" value="Efflux_drug-R_Bcr/CmlA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00710">
        <property type="entry name" value="efflux_Bcr_CflA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="51"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="79"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="102"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="167"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="216"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="251"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="280"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="306"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="344"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="370"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="8">
        <location>
            <begin position="13"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="402" mass="42455" checksum="4124422EF2ACCFD0" modified="2010-01-19" version="1">MIQQSSSVKMARLLFLLIILVAVGQMTQTMYVPAIPEMAAAFATKSAYLQAVMAAYLIPYGLSQFIYGPISDKIGRRPVTIAGMSIFLAGTVLALFSSSFELFLAASFIQGCGTGCSGAMSRTVTRDCYEGADLHKANSLISMGVIFSPLIAPVLGGYLSTHMGWKASYGFLLIFGAFVTIAMMAWFSETLPVEKRRTDSAMASYRYVLSNRQFQGYVLCLIATFAGIAAFEAAAGVLLGSVLKLDPTTVSWLFIVPLPGYLMGAWCSSMLVGRIGNRRVLYIGMAALALGAVTILIPGIEGLVTVTSLIGGAFIYFFGAGILFPSATTAAIEPFPNHAGTAGAVLGGLQNLGAGIATLAASFMRASDQFSLGSVLSVMAIIVIVSLFLVRRSQHHSPVMAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY46</accession>
    <name>D0YY46_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chaperone protein TorD</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">torD</name>
        <name evidence="4" type="ORF">VDA_002209</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TorD/DmsD family. TorD subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299653.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002209"/>
    <dbReference type="EnsemblBacteria" id="EEZ41177">
        <property type="protein sequence ID" value="EEZ41177"/>
        <property type="gene ID" value="VDA_002209"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3381">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1995553at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051259">
        <property type="term" value="P:protein complex oligomerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01150">
        <property type="entry name" value="TorD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023069">
        <property type="entry name" value="Chaperone_TorD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020945">
        <property type="entry name" value="DMSO/NO3_reduct_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036386">
        <property type="entry name" value="HscB_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036411">
        <property type="entry name" value="TorD-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02613">
        <property type="entry name" value="Nitrate_red_del"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89155">
        <property type="entry name" value="SSF89155"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1 3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="215" mass="24365" checksum="89D6BCECD25484F6" modified="2010-01-19" version="1">MQEFIAFNEQRAEIYWWMSSLFAHELTSENIQNYQGGEMCNFLSGLAMTAELKAPVEALRAALTKLETREDAQLELAADFCGLFLSTPKSGALPYASMYVGKTGLLNDKPAQEMNELMNQYGIAQRKEFNEPADHLAVELDFMGNLIIMANQQPTEEQREELMLAQKEFVETKLLNWLPQFSQTCHRFDQFGFYAAASSLLVAFCQLDLTFLAGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY67</accession>
    <name>D0YY67_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ABC transporter substrate-binding protein YnjB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299697.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002230"/>
    <dbReference type="EnsemblBacteria" id="EEZ41198">
        <property type="protein sequence ID" value="EEZ41198"/>
        <property type="gene ID" value="VDA_002230"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4134">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="447734at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027020">
        <property type="entry name" value="YnjB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029172">
        <property type="entry name" value="UCP029172_ABC_sbc_YnjB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019233" evidence="1">
        <location>
            <begin position="24"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="405" mass="45416" checksum="EEA8F2904BBE0084" modified="2010-01-19" version="1">MLTKSFKHIACALLASFSLLSYAQESDSKQDLTSPLHDNWQHIVAKAKGQTVYFNAWGGSQEINEYLRWANQELQQQYGVTLKQVKVADISETVQRLVAEKAAGKNHDGSVDMVWINGENFRTMKQNNLLFGPFVHQLPNWALVNKKLPVEQDFTQATEGYEAPWGVGQLVFIYDSAKLSNPPKSFTQLLTFAQQHPGKVSYPKPPEFHGSSFLKAALLELTPDKKALYQPLVLPQDQATFDRVTAPLWHYLDQLHKVAWQQGKKFPSGSAEIMQLLDDQQLLLAITFNPNAAKAAIENGNLTETAKTYAFDQGALTNVHFLAIPWNAQAKEGAMVAINFLMSPQAQARKADTTIWGDPTVLTTQALQKDQAKGQSTFQLYKAISEPDPSWLTAIEHKWQQRYGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY69</accession>
    <name>D0YY69_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter ATP-binding protein YnjD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_002232</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299701.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002232"/>
    <dbReference type="EnsemblBacteria" id="EEZ41200">
        <property type="protein sequence ID" value="EEZ41200"/>
        <property type="gene ID" value="VDA_002232"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4136">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1200451at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="4"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="210" mass="23509" checksum="6EA6E2D95F2AB5E0" modified="2010-01-19" version="1">MTSLIIKELTVKNHHTPIFGPMSFTVKPGEVLSLMGPSGCGKSTLLNIVAGHNNTPFTYTGNLYLGHKSLDKLPAYQREIGLLFQDDLLFPHLNIWENLAFALPAEIKDTKRHQQALEALESIGLITLANHHPSQVSGGQRARISLMRTLLAKPKAILLDEPFSKLDPDLRQDFRQFVFNHISDCNVPTLMVTHNSEDIPLNGKVLTWPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYR0</accession>
    <name>D0YYR0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phasin_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002423</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002423"/>
    <dbReference type="EnsemblBacteria" id="EEZ41391">
        <property type="protein sequence ID" value="EEZ41391"/>
        <property type="gene ID" value="VDA_002423"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5032W8B">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018968">
        <property type="entry name" value="Phasin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014176">
        <property type="entry name" value="Phasin_subfam-3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09361">
        <property type="entry name" value="Phasin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02809">
        <property type="entry name" value="phasin_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phasin_2" evidence="1">
        <location>
            <begin position="3"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="68" mass="7562" checksum="ADCF728924F330DE" modified="2010-01-19" version="1">MGIEQMKSVGEIRDVTSLAAYNSQQMAVLTKLSQQMVEDSNKLQSIAKEFKEDLEKLSSENLKTVTPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYS3</accession>
    <name>D0YYS3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">MotA/TolQ/ExbB proton channel family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_002436</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the exbB/tolQ family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002436"/>
    <dbReference type="EnsemblBacteria" id="EEZ41404">
        <property type="protein sequence ID" value="EEZ41404"/>
        <property type="gene ID" value="VDA_002436"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0811">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043213">
        <property type="term" value="P:bacteriocin transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002898">
        <property type="entry name" value="MotA_ExbB_proton_chnl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014163">
        <property type="entry name" value="Tol-Pal_TolQ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01618">
        <property type="entry name" value="MotA_ExbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02796">
        <property type="entry name" value="tolQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="138"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="MotA_ExbB" evidence="9">
        <location>
            <begin position="46"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ41404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="194" mass="21554" checksum="FBE23F7193660D00" modified="2010-01-19" version="1">MIIKRSQVLSEATTRAHRFEDRFWSGVDLSQLYKEVEARKDDLTGSEQIFYAGFKEYARLHRSNGKVPEAVMEGTGRAMRVALSREVEELETNLPFLATVGSISPYIGLFGTVWGIMHAFIALGAVKQATLAMVAPGIAEALVATAMGLFAAIPAVMFYNRLTNRVAKLEHTYATFMEEFSSILHRQAFAANQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYU5</accession>
    <name>D0YYU5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Potassium voltage-gated channel subfamily KQT</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">VDA_002458</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300132.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002458"/>
    <dbReference type="EnsemblBacteria" id="EEZ41426">
        <property type="protein sequence ID" value="EEZ41426"/>
        <property type="gene ID" value="VDA_002458"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2126">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1991946at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008076">
        <property type="term" value="C:voltage-gated potassium channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005249">
        <property type="term" value="F:voltage-gated potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028325">
        <property type="entry name" value="VG_K_chnl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027359">
        <property type="entry name" value="Volt_channel_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11537">
        <property type="entry name" value="PTHR11537"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0630">Potassium</keyword>
    <keyword evidence="5" id="KW-0631">Potassium channel</keyword>
    <keyword evidence="3" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="54"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="88"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="150"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="209"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="Ion_trans" evidence="12">
        <location>
            <begin position="24"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ41426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="272" mass="30686" checksum="BF4B50B4AE969FE0" modified="2010-01-19" version="1">MVTLTPRQRLYQIIFGTQTRYGQLFDIGLIIAIISSEVILIISSVTSIESKFSTTLYILEWFFTLLFTVEYILRLYCSPKPWAYARSFYGLIDLIAIVPAYIAFFIPGSNYLLIVRLIRVLRIFRVLKLARYLRDSNILLRSLMQAQRKILVFFSSVLVLVTVFGSLMFIIEGPDNGFTSIPQSIYWAIVTITTVGYGDLVPHTVLGKAVASLTMLLGYSILAVPTGIITAEINQEINHHKALIRCPNCATSGHDMDADYCRKCGSKLPEHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYW3</accession>
    <name>D0YYW3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_002476</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Nucleoid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the histone-like protein H-NS family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300165.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002476"/>
    <dbReference type="EnsemblBacteria" id="EEZ41444">
        <property type="protein sequence ID" value="EEZ41444"/>
        <property type="gene ID" value="VDA_002476"/>
    </dbReference>
    <dbReference type="GeneID" id="57341303"/>
    <dbReference type="eggNOG" id="COG2916">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1911889at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009295">
        <property type="term" value="C:nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027444">
        <property type="entry name" value="H-NS_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037150">
        <property type="entry name" value="H-NS_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001801">
        <property type="entry name" value="Histone_HNS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027454">
        <property type="entry name" value="Histone_HNS_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00816">
        <property type="entry name" value="Histone_HNS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002096">
        <property type="entry name" value="HnS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00528">
        <property type="entry name" value="HNS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNS" evidence="9">
        <location>
            <begin position="84"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="DNA-binding region" evidence="6">
        <location>
            <begin position="109"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="98"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="23"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="117"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR002096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR002096-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ41444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="131" mass="14941" checksum="B989A2F787D28A88" modified="2010-01-19" version="1">MSDAMKALLNLRSLRALSREYTLEQLQEALEKLQTVVSEREESEAEEIAKENERNQKLEQYREMLLADGIDPEELLASLSKAPKAKRAARPAKYKFIDENGEEKTWTGQGRTPSALKKALDEGKSLEEFEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ11</accession>
    <name>D0YZ11_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional activator ToxR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_002524</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300253.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002524"/>
    <dbReference type="EnsemblBacteria" id="EEZ41492">
        <property type="protein sequence ID" value="EEZ41492"/>
        <property type="gene ID" value="VDA_002524"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3710">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1497441at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="5"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="1">
        <location>
            <begin position="5"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="299" mass="33294" checksum="6C8EB6E296C43928" modified="2010-01-19" version="1">MHKTSAKHCIGQRFIFDPYDNSLIDTVENNELIRLGSNESRALSLLIDEPGAIITRNRLHDYVWREQGFEVDDSSLTQCISTLRKALKDPTKSPEYVKTVPKRGYQMIATVEKYVDMPLAITATEHAEDLTSVPEHHYQDSALVTAPQSAVEVELSNIQQPQQPISTEPVQQKSSAKVTGSRSLLSIIALILALLIPLASYFAPAKASDNFIPLFSVKGVQVVTPNNNPIMNDWQSLISTCITSYLDNHQQESKPVKVIVTGGQSNQVWLNYIHTAQTANENVTLRLLTSHEDNANLCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ95</accession>
    <name>D0YZ95_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Flagellar hook-associated protein FlgL</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_002608</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Bacterial flagellum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the bacterial flagellin family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300474.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002608"/>
    <dbReference type="EnsemblBacteria" id="EEZ41576">
        <property type="protein sequence ID" value="EEZ41576"/>
        <property type="gene ID" value="VDA_002608"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1344">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1788350at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009424">
        <property type="term" value="C:bacterial-type flagellum hook"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013384">
        <property type="entry name" value="Flagell_FlgL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001492">
        <property type="entry name" value="Flagellin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046358">
        <property type="entry name" value="Flagellin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001029">
        <property type="entry name" value="Flagellin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42792">
        <property type="entry name" value="PTHR42792"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00700">
        <property type="entry name" value="Flagellin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00669">
        <property type="entry name" value="Flagellin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02550">
        <property type="entry name" value="flagell_flgL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="7" id="KW-0966">Cell projection</keyword>
    <keyword evidence="7" id="KW-0969">Cilium</keyword>
    <keyword evidence="7" id="KW-0282">Flagellum</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flagellin_N" evidence="5">
        <location>
            <begin position="4"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="Flagellin_C" evidence="6">
        <location>
            <begin position="330"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="412" mass="45004" checksum="7D920B26A27D6E39" modified="2010-01-19" version="1">MSRISTLSQYNNLTSNLMRKQTQLSHTNNQLATGKRVDTSGDDPVSSISIQNYKQQLTQIGQYKDAITLANNRLGVLETNIAGVEDNLDVTKQKVLGMLNGAMAANDRKAFKDELQSLYDGLLSLANSKDEAGNYIFAGNQMDTKPFIEKDGYMTYQGDSQSRQTQIDSNMNVKTSLPGDQVFMDIPNPYGDFRPNFAGLTEGSKAHVLSADISDFSKAKAIQVSFSDGGTTAGPNGETVKVTNYSLSIDGTEVVKDQPYDPEKGIEYTGSTAGDPTLNLKFAEMQDGDTITLQPAQSFNIFDSIQAAITYADAPTSSPEAQANLQRVIDDLDAGFVHMNQQRSEVGSIMKQVERQQEQHLDFELTLNTAHGGLEDLDYSSAVLDLNQQAMALQASQAAFSQTKNLSLFNYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZB1</accession>
    <name>D0YZB1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_002624</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300524.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002624"/>
    <dbReference type="EnsemblBacteria" id="EEZ41592">
        <property type="protein sequence ID" value="EEZ41592"/>
        <property type="gene ID" value="VDA_002624"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502ZAC4">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="969942at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1660.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032388">
        <property type="entry name" value="FlgT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038165">
        <property type="entry name" value="FlgT_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032386">
        <property type="entry name" value="FlgT_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032370">
        <property type="entry name" value="FlgT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038180">
        <property type="entry name" value="FlgT_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16538">
        <property type="entry name" value="FlgT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16539">
        <property type="entry name" value="FlgT_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16548">
        <property type="entry name" value="FlgT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FlgT_N" evidence="3">
        <location>
            <begin position="26"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="FlgT_M" evidence="2">
        <location>
            <begin position="116"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="FlgT_C" evidence="1">
        <location>
            <begin position="301"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="381" mass="42705" checksum="CAA73D79107F745B" modified="2010-01-19" version="1">MKKILVALLNFSVMLGGVFSLPVHAKWLEVTGQAVILESESTARINALEDAIYQAIIFSGADIATLSNIKPYLSEKNKEYRFSGNEVRQVSVLKTDKQGGKFYLTARIDIYPAAKSCHKTQYKKPLLLSDFTLLSQQQAVMGGIYQVGEDFTTMLKRQIQQRSQSFVVAGTTHIPFNANNPSMMMMLAEDKDAQYLISGQITDISATLDQKLLKKDQVNRQFATSMTIMDGKTGEILFEKNYRDIALWPFSRTSTVDTKSARFWQSPYGLAVERVSRNMMLDLENSLSCRTSLPEIVSAHGNMAQMNVGRIHGVKEGDRLKLWHSASFIDQMGIPRTRMVATQLTLVVSRVYEKSAELIINQPDLAASIQTGDLLTKQVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZD0</accession>
    <name>D0YZD0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Sensor protein</fullName>
            <ecNumber evidence="14">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">VDA_002643</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell inner membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="14"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300584.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002643"/>
    <dbReference type="EnsemblBacteria" id="EEZ41611">
        <property type="protein sequence ID" value="EEZ41611"/>
        <property type="gene ID" value="VDA_002643"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3850">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.960">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029095">
        <property type="entry name" value="NarX-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042295">
        <property type="entry name" value="NarX-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016380">
        <property type="entry name" value="Sig_transdc_His_kin_NarX/NarQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13675">
        <property type="entry name" value="PilJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003167">
        <property type="entry name" value="STHK_NarX/NarQ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 14" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4 14" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="13 14 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="12 14" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="151"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="17">
        <location>
            <begin position="175"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="16">
        <location>
            <begin position="368"/>
            <end position="563"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRNR" id="PIRNR003167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EEZ41611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="568" mass="64411" checksum="A6CC56F75DD03A0F" modified="2010-01-19" version="1">MPSRPFKPVTTTIARAMLCILLLSVITTSFALLTLASSLNDAEAVNVSGSLRMQSYRLAYDIQTHSEQLPHHIAKFEHSLFAEPMAELDSLIVPRRIKLHYYSLIDRWHELKPDSLAKQQKYLTNVADFVTRIDKFVFELQEFSITKLRMLAVLGGMGLTLILCVALFVIHFTQRQVVTPLNRLVSASKRIKQGEFDLHLAITNNNELGLLTNTFNTMASELGKLYHGLEQKVNEKTHRLRHANDSLQILYQCSQELSVSRLSEENFHTMLNTLVALEGLTAVKLSISESNGHQYEIESGVVDIHCSWHYQDLAIDGEVLGQLWWQYSLPCPDQALIDNIARILARGIYYNRAQKQTEQLLIMEERATIARELHDSLAQSLSYLKIQLTLLKRQINKDNSQQAKEILADIEQGLSGAYTQLRELLSTFRLTVAEADFAQALTTMVEPLEEQTNAVIVVDNQLSSLHLQAHHQIHLLQVIREALLNAIKHANADEILIRCLQQGDKIAISIKDDGDGFDPRNPKLNHYGLAIMNERAARLHGQLEIHTQPQKGCEIELTFLLPKEDQNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZE5</accession>
    <name>D0YZE5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Na(+)-translocating NADH-quinone reductase subunit D</fullName>
            <shortName evidence="15">Na(+)-NQR subunit D</shortName>
            <shortName evidence="15">Na(+)-translocating NQR subunit D</shortName>
            <ecNumber evidence="15">7.2.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">NQR complex subunit D</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="15">NQR-1 subunit D</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">nqrD</name>
        <name evidence="16" type="ORF">VDA_002658</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>a ubiquinone + H(+) + n Na(+)(in) + NADH = a ubiquinol + n Na(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:47748"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="7.2.1.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="15">Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="15">Cell membrane</location>
            <topology evidence="15">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the NqrDE/RnfAE family.</text>
    </comment>
    <dbReference type="EC" id="7.2.1.1" evidence="15"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300626.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002658"/>
    <dbReference type="EnsemblBacteria" id="EEZ41626">
        <property type="protein sequence ID" value="EEZ41626"/>
        <property type="gene ID" value="VDA_002658"/>
    </dbReference>
    <dbReference type="GeneID" id="57341076"/>
    <dbReference type="eggNOG" id="COG1347">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1782047at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016655">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00428">
        <property type="entry name" value="NqrD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011292">
        <property type="entry name" value="NqrD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003667">
        <property type="entry name" value="NqrDE/RnfAE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30586:SF1">
        <property type="entry name" value="PTHR30586:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02508">
        <property type="entry name" value="Rnf-Nqr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006102">
        <property type="entry name" value="NQR_DE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01939">
        <property type="entry name" value="nqrD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4 15" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11 15" id="KW-0406">Ion transport</keyword>
    <keyword evidence="13 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 15" id="KW-0520">NAD</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 15" id="KW-0915">Sodium</keyword>
    <keyword evidence="14 15" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="7 15" id="KW-1278">Translocase</keyword>
    <keyword evidence="6 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 15" id="KW-0813">Transport</keyword>
    <keyword evidence="12 15" id="KW-0830">Ubiquinone</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="73"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="101"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="130"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="179"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EEZ41626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="210" mass="22770" checksum="954A88254139E701" modified="2010-01-19" version="1">MADTKEMKKILFGPFIANNPIALQILGVCSALAVTTKLETAVVMTLAVTAVTAFSNLFVSLVRNQIPNSVRIIAQMAIIASLVIVVDQVLKAYLYDISKQLSVFVGLIITNCIVMGRAEAYAMKSAPLPSFIDGIGNGLGYGFVLITVAFFRELLGSGKLFGVQVLPLVSDGGWYQPNGMMLLAPSAFFLIGFMIWIIRTFRPEQVEAKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZF0</accession>
    <name>D0YZF0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002663</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300641.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002663"/>
    <dbReference type="EnsemblBacteria" id="EEZ41631">
        <property type="protein sequence ID" value="EEZ41631"/>
        <property type="gene ID" value="VDA_002663"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3056">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1568521at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005619">
        <property type="entry name" value="Uncharacterised_YajG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03923">
        <property type="entry name" value="Lipoprotein_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019264" evidence="1">
        <location>
            <begin position="26"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="194" mass="21388" checksum="FA96050F653C721C" modified="2010-01-19" version="1">MSTIKTSFLALVTLLLSACASQPTALPTIPLTPTLTLTHQSLNVSEPMQLQVNDLRQLKYIAIVDSGRNNVDAYQSRQPLTEVFHRALSQQLQSQGVKLVSQNSNKMTIAIQTAQVNVDQSLVKYQMNTALQLSLTVTTSHGKFVKQYSGKASKEAPLEASLEDMQQSMDKLISSVLHDIATDAELNQYLKENL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZG8</accession>
    <name>D0YZG8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Riboflavin biosynthesis protein RibD</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="10">Diaminohydroxyphosphoribosylaminopyrimidine deaminase</fullName>
                <shortName evidence="10">DRAP deaminase</shortName>
                <ecNumber evidence="10">3.5.4.26</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="10">Riboflavin-specific deaminase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="10">5-amino-6-(5-phosphoribosylamino)uracil reductase</fullName>
                <ecNumber evidence="10">1.1.1.193</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="10">HTP reductase</fullName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="15" type="ORF">VDA_002681</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + H(+) + H2O = 5-amino-6-(5-phospho-D-ribosylamino)uracil + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:21868"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:58453"/>
            <dbReference type="ChEBI" id="CHEBI:58614"/>
            <dbReference type="EC" id="3.5.4.26"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>5-amino-6-(5-phospho-D-ribitylamino)uracil + NADP(+) = 5-amino-6-(5-phospho-D-ribosylamino)uracil + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:17845"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58421"/>
            <dbReference type="ChEBI" id="CHEBI:58453"/>
            <dbReference type="EC" id="1.1.1.193"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10 13">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="10 13">Binds 1 zinc ion.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Cofactor biosynthesis; riboflavin biosynthesis; 5-amino-6-(D-ribitylamino)uracil from GTP: step 2/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Cofactor biosynthesis; riboflavin biosynthesis; 5-amino-6-(D-ribitylamino)uracil from GTP: step 3/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 10">In the C-terminal section; belongs to the HTP reductase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.26" evidence="10"/>
    <dbReference type="EC" id="1.1.1.193" evidence="10"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300688.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002681"/>
    <dbReference type="EnsemblBacteria" id="EEZ41649">
        <property type="protein sequence ID" value="EEZ41649"/>
        <property type="gene ID" value="VDA_002681"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0117">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1985">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1775351at2"/>
    <dbReference type="UniPathway" id="UPA00275">
        <property type="reaction ID" value="UER00401"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008703">
        <property type="term" value="F:5-amino-6-(5-phosphoribosylamino)uracil reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008835">
        <property type="term" value="F:diaminohydroxyphosphoribosylaminopyrimidine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016192">
        <property type="entry name" value="APOBEC/CMP_deaminase_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004794">
        <property type="entry name" value="Eubact_RibD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011549">
        <property type="entry name" value="RibD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002734">
        <property type="entry name" value="RibDG_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01872">
        <property type="entry name" value="RibD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006769">
        <property type="entry name" value="RibD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="SSF53597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00326">
        <property type="entry name" value="eubact_ribD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00227">
        <property type="entry name" value="ribD_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00903">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 10 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="10 12" id="KW-0521">NADP</keyword>
    <keyword evidence="10 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0686">Riboflavin biosynthesis</keyword>
    <keyword evidence="8 10 13" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="14">
        <location>
            <begin position="4"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="11">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="210"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="237"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="304"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="306"/>
            <end position="312"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR006769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR006769-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR006769-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR006769-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEZ41649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="378" mass="40922" checksum="C6622B2B335D4B85" modified="2010-01-19" version="1">MFSAFDHKMMSRAIALAKKGRFTTAPNPNVGCVIVNNGQIVGEGFHYRAGLPHAEVFALRAAGDKARGATAYVTLEPCSHYGRTPPCALALIEAGISRVVCAMVDPNPKVAGNGVTLLQNAGVTVEVGLLEQDAKALNLGFIKAMQTGMPYVQLKMASSLDGRTALANGESKWITGPQARADVQHFRAQAGAILSTSATVIADDPSMNIRWQELPFYIQQQYPKSELRLPIRVIIDSQNRLSPDYQLFHLPGKTLLARCEQGDEVWPDSVTQLIISRTPDSSQLDLHELLQQLVKLGIYHIWVEAGAGLAGALVQNQLVDSFILYQAPKLMGAEARGVMNLPQLTAMGQVPNVSISDLRMVGTDIRITADIHSSYAPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZH3</accession>
    <name>D0YZH3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Membrane-bound lytic murein transglycosylase F</fullName>
            <ecNumber evidence="7">4.2.2.n1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Murein lyase F</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">mltF</name>
        <name evidence="9" type="ORF">VDA_002686</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>Exolytic cleavage of the (1-&gt;4)-beta-glycosidic linkage between N-acetylmuramic acid (MurNAc) and N-acetylglucosamine (GlcNAc) residues in peptidoglycan, from either the reducing or the non-reducing ends of the peptidoglycan chains, with concomitant formation of a 1,6-anhydrobond in the MurNAc residue.</text>
            <dbReference type="EC" id="4.2.2.n1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell outer membrane</location>
            <topology evidence="7">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
        <text evidence="7">Attached to the inner leaflet of the outer membrane.</text>
    </comment>
    <comment type="domain">
        <text evidence="7">The N-terminal domain does not have lytic activity and probably modulates enzymatic activity. The C-terminal domain is the catalytic active domain.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the transglycosylase Slt family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">In the C-terminal section; belongs to the transglycosylase Slt family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">In the N-terminal section; belongs to the bacterial solute-binding protein 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="4.2.2.n1" evidence="7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002686"/>
    <dbReference type="EnsemblBacteria" id="EEZ41654">
        <property type="protein sequence ID" value="EEZ41654"/>
        <property type="gene ID" value="VDA_002686"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4623">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1444566at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016837">
        <property type="term" value="F:carbon-oxygen lyase activity, acting on polysaccharides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008933">
        <property type="term" value="F:lytic transglycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016998">
        <property type="term" value="P:cell wall macromolecule catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000270">
        <property type="term" value="P:peptidoglycan metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02016">
        <property type="entry name" value="MltF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023703">
        <property type="entry name" value="MltF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000189">
        <property type="entry name" value="Transglyc_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008258">
        <property type="entry name" value="Transglycosylase_SLT_dom_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01464">
        <property type="entry name" value="SLT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00062">
        <property type="entry name" value="PBPb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00922">
        <property type="entry name" value="TRANSGLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0732">Signal</keyword>
    <feature type="domain" description="PBPb" evidence="8">
        <location>
            <begin position="45"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="LT domain" evidence="7">
        <location>
            <begin position="272"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="498" mass="56558" checksum="7C0F06BDC4D7100B" modified="2010-01-19" version="1">MLSTYTLPKKIRQYFVSLITLFLISGCQWQSEPHNALDRIRETGVLRVGTLNNQLSYYIGNEGPTGLDYELAQLFAKKLGVKLEMQPMFSLSSLFPALDRGNVDILAAGLTITPNRLQDFRATPAYYYASQLVVYKKGTWRPRTPADLAKNKGTLTVVKGSSHELQLKQLQQKYPDLKWQAVSETDDDELMRDVASGKLDFTIADSVDVALIQRIHPDIAIAMELTDEEPISWFVKNSSNDNLYALIIEFFGEIKQNGELAQLEEKYFGHVDQFDYVDTRAFLRAVEGKLPKWKPLFKQYAGEFDWRLIAALSYQESHWNPEATSPTGVRGMMMLTTPTAKAVDVTNRLDPKQSIRGGTEYLRRMIARVPDSIESHEKVWFALASYNIGFGHLMDARRLTKAQGGNPDTWTDVKQRLPMLRQRQYYTQTRYGYARGDEALNYVENIRRYYQSIVGYEQAHSREHQGDGVEIVDGLQTITPQTISAAAKPQPAKVAASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZH7</accession>
    <name>D0YZH7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">S-formylglutathione hydrolase</fullName>
            <ecNumber evidence="3 7">3.1.2.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_002690</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Serine hydrolase involved in the detoxification of formaldehyde.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>H2O + S-formylglutathione = formate + glutathione + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14961"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:57688"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="EC" id="3.1.2.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the esterase D family.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.12" evidence="3 7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300709.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002690"/>
    <dbReference type="ESTHER" id="lisda-d0yzh7">
        <property type="family name" value="A85-EsteraseD-FGH"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41658">
        <property type="protein sequence ID" value="EEZ41658"/>
        <property type="gene ID" value="VDA_002690"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0627">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1828423at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018738">
        <property type="term" value="F:S-formylglutathione hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046294">
        <property type="term" value="P:formaldehyde catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000801">
        <property type="entry name" value="Esterase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014186">
        <property type="entry name" value="S-formylglutathione_hydrol"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10061">
        <property type="entry name" value="PTHR10061"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00756">
        <property type="entry name" value="Esterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02821">
        <property type="entry name" value="fghA_ester_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0719">Serine esterase</keyword>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="150"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="226"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR614186-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ41658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="281" mass="31545" checksum="D88AECE10F74081D" modified="2010-01-19" version="1">MTLENISCNKSAGGWHKQYTHHSEVLSCDMRFAIFLPPQTATGKKVPVLYWLSGLTCTDENFMQKAGAQRIAAELGIAIVAPDTSPRGENVPDDENGAYDFGLGAGFYVNATQAPWDRHYRMYDYVVNELPAIIEANFPVTEQRAISGHSMGGHGALMISLRNPERFSSVSAFSPIANPINCPWGQKAFNGYLGDNPKEWKNYDSSELMRLAEKKLPTLVDQGTQDNFYIDGQLRPESLVAAAEANEYPLELRMQDGYDHSYYFMASFIEDHLRFHMKHFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZH9</accession>
    <name>D0YZH9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">GMP synthase [glutamine-hydrolyzing]</fullName>
            <ecNumber evidence="9">6.3.5.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">GMP synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Glutamine amidotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">guaA</name>
        <name evidence="12" type="ORF">VDA_002692</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Catalyzes the synthesis of GMP from XMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + H2O + L-glutamine + XMP = AMP + diphosphate + GMP + 2 H(+) + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:11680"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.5.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Purine metabolism; GMP biosynthesis; GMP from XMP (L-Gln route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.2" evidence="9"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002692"/>
    <dbReference type="EnsemblBacteria" id="EEZ41660">
        <property type="protein sequence ID" value="EEZ41660"/>
        <property type="gene ID" value="VDA_002692"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0518">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0519">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00189">
        <property type="reaction ID" value="UER00296"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003922">
        <property type="term" value="F:GMP synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016462">
        <property type="term" value="F:pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01742">
        <property type="entry name" value="GATase1_GMP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01997">
        <property type="entry name" value="GMP_synthase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00344">
        <property type="entry name" value="GMP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001674">
        <property type="entry name" value="GMP_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004739">
        <property type="entry name" value="GMP_synth_GATase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022955">
        <property type="entry name" value="GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025777">
        <property type="entry name" value="GMPS_ATP_PPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022310">
        <property type="entry name" value="NAD/GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00958">
        <property type="entry name" value="GMP_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02540">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00884">
        <property type="entry name" value="guaA_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00888">
        <property type="entry name" value="guaA_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51553">
        <property type="entry name" value="GMPS_ATP_PPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="5 9 10" id="KW-0332">GMP biosynthesis</keyword>
    <keyword evidence="3 9 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 9 10" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GMPS ATP-PPase" evidence="11">
        <location>
            <begin position="187"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9">
        <location>
            <position position="65"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="160"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="162"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="214"/>
            <end position="220"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ41660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="504" mass="56036" checksum="5E7B8BE63E6999EA" modified="2010-01-19" version="1">MIARRIREIGVYCELWSWDVDEADIRDFNPNGIILSGGPESVTEAGSPRAPQYVFEAGVPVFGVCYGMQTMAEQLGGKVAGSSEREFGYAQVKIVEPTDLFKNIEDAIAEDGTPLLDVWMSHGDKVVEIPADFTKVAETSTCPYAAMANDEKRFYGVQFHPEVTHTRQGMRIIENFVLNVCGCEKLWTSANIIEDAIARIKEQVGDDEVILGLSGGVDSSVVAMLVHRAIGDKLTCVFVDNGLLRLNEGEQVMDMFGDHFGLNIVHVKAENRFLEALAGVDEPEAKRKIIGRVFVEVFDEESKKLQNAKWLAQGTIYPDVIESAASKTGKAHVIKSHHNVGGLPDDMQMGLVEPLKELFKDEVRKIGLELGLPYNMLYRHPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELHNADLYNKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETIDFMTAHWAHLPYDFLGKVSNRIINEVDGISRVVYDVSGKPPATIEWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZK4</accession>
    <name>D0YZK4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein-export membrane protein SecF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">secF</name>
        <name evidence="10" type="ORF">VDA_002717</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the SecD/SecF family. SecF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002717"/>
    <dbReference type="EnsemblBacteria" id="EEZ41685">
        <property type="protein sequence ID" value="EEZ41685"/>
        <property type="gene ID" value="VDA_002717"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0341">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015450">
        <property type="term" value="F:protein-transporting ATPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043952">
        <property type="term" value="P:protein transport by the Sec complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01464_B">
        <property type="entry name" value="SecF_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022813">
        <property type="entry name" value="SecD/SecF_arch_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022645">
        <property type="entry name" value="SecD/SecF_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022646">
        <property type="entry name" value="SecD/SecF_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005665">
        <property type="entry name" value="SecF_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30081">
        <property type="entry name" value="PTHR30081"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07549">
        <property type="entry name" value="Sec_GG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02355">
        <property type="entry name" value="SecD_SecF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01755">
        <property type="entry name" value="SECFTRNLCASE"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00916">
        <property type="entry name" value="2A0604s01"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00966">
        <property type="entry name" value="3a0501s07"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="112"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="164"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="211"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="237"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ41685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="289" mass="31096" checksum="513CCBFB80668BEB" modified="2010-01-19" version="1">MVSLSIATVATKGLNWGLDFTGGTLIEVSFENPANLGQIREALEKADFGDAVVQNFGTARDVMVRLQPRDGVKGEVLGGQIISALKEGTGQNVEMRRIEFVGPNVGDELAEAGGLAILISLLCILMYVSLRFEWRLAAGAVMSLAHDVIITVGIFSFLQVEVDLTIVAALLTVVGYSLNDTIVVFDRIRENFRKMRKGNASDIINSSISQTLSRTLITSGTTLFVVIALFLKGGTMIHGFAMALLIGITVGTYSSIYVASALALKLGITREHLMPPQVEKEGEEFDAMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZM0</accession>
    <name>D0YZM0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Polyphosphate kinase</fullName>
            <ecNumber evidence="6 7">2.7.4.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">ATP-polyphosphate phosphotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Polyphosphoric acid kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ppk</name>
        <name evidence="10" type="ORF">VDA_002733</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>[phosphate](n) + ATP = [phosphate](n+1) + ADP</text>
            <dbReference type="Rhea" id="RHEA:19573"/>
            <dbReference type="Rhea" id="RHEA-COMP:9859"/>
            <dbReference type="Rhea" id="RHEA-COMP:14280"/>
            <dbReference type="ChEBI" id="CHEBI:16838"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="PTM">
        <text evidence="6 7">An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the polyphosphate kinase 1 (PPK1) family.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.1" evidence="6 7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300852.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002733"/>
    <dbReference type="EnsemblBacteria" id="EEZ41701">
        <property type="protein sequence ID" value="EEZ41701"/>
        <property type="gene ID" value="VDA_002733"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0855">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="76567at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009358">
        <property type="term" value="C:polyphosphate kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008976">
        <property type="term" value="F:polyphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019637">
        <property type="term" value="P:organophosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006799">
        <property type="term" value="P:polyphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1840.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00347">
        <property type="entry name" value="Polyphosphate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003414">
        <property type="entry name" value="PP_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041108">
        <property type="entry name" value="PP_kinase_C_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024953">
        <property type="entry name" value="PP_kinase_middle"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036830">
        <property type="entry name" value="PP_kinase_middle_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025200">
        <property type="entry name" value="PPK_C_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025198">
        <property type="entry name" value="PPK_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036832">
        <property type="entry name" value="PPK_N_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30218">
        <property type="entry name" value="PTHR30218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02503">
        <property type="entry name" value="PP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13090">
        <property type="entry name" value="PP_kinase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17941">
        <property type="entry name" value="PP_kinase_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13089">
        <property type="entry name" value="PP_kinase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015589">
        <property type="entry name" value="PP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140356">
        <property type="entry name" value="SSF140356"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03705">
        <property type="entry name" value="poly_P_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 6 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1 6 7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PLD phosphodiesterase" evidence="9">
        <location>
            <begin position="577"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="61"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphohistidine intermediate" evidence="6">
        <location>
            <position position="425"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="365"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="395"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="458"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="554"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="582"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ41701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="685" mass="79658" checksum="926A28C1A44BD54A" modified="2010-01-19" version="1">MDMRFINKELSWLSFNHRVLQEAEDSSVPLIERARFLGIYANNLDEFYKVRIAEIKRHILIESERNKGDNAQLLLARLQQKIDQQNERFTAAYDHIIHALQKQHIHLNGIESLAGYQRAWLQQYFSQNILPHLTPQLLSVHSQFHNHGSYLAVIIEQEDKHIYALVDIPTQLDVFIKIPTHHATHHHLIFLDEVIRFYLTKLFQPLFSYRQLHCYAITITRDSQLDWSLDEEQSVLDKLSLSLTQRLSAPTVRLVYQDNMPDALLQYLCQLLNIDDPLSLQPTGNFHNDKWLMQFPSIGNDHLVHPKLPPLISTQLAKNPNPFLAISAHDVLLYYPYHDFLPLTELIRLAAFDPLVHSIKINIYRLASQSRIVRSLIQAAKNGKQVTVIVELQARFDEEANLSWAKQLQQAGVHVLFGVPGLKIHSKLCLITRSEHGKWARYAHIGTGNFNEDSAQVYTDFSLLTADKKLTKEVRDVFRYIANPYYDCQFEHLLVSPRNMRQKLYHLIKQERKAVKQGHIGKIVLKLNNLTDEGLIEKLYQASQDGVEITLIIRGMCSLQTEDDSLSKNIRVISIVDRFLEHSRVMIFHNQGQPDVYISSADWMTRNVDRRIEVGCPIYDPQLKQTIIDIMALHLQDSVKARVIDAKQSNQYRQRVTTGKKVRSQLAIYRYLKRQEKRLGRQHEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZT5</accession>
    <name>D0YZT5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002798</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301036.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002798"/>
    <dbReference type="EnsemblBacteria" id="EEZ41766">
        <property type="protein sequence ID" value="EEZ41766"/>
        <property type="gene ID" value="VDA_002798"/>
    </dbReference>
    <dbReference type="GeneID" id="57340923"/>
    <dbReference type="eggNOG" id="COG1396">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1450255at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13443">
        <property type="entry name" value="HTH_26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="7"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="212" mass="23395" checksum="F1B724588D07D512" modified="2010-01-19" version="1">MEYLERIKRLAKIQGISQKQLGEALGLQQGTMSRKLSGKYGIEVRELETIATTLNTSIGYILTGQVDTGTQATTTITNESATGSTCTYIPVIHRKDFTSYASGDTVDVVSKRAIPQHLDREECLGLLVDNENIAQCAPVGSYALATKTAQYRPKQPVFASVRGSEPDFYHMTQLADGVVFSTSQPDFPNLFVNNGEFEVHGYIIQSDWAYDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZY0</accession>
    <name>D0YZY0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">D-alanyl-D-alanine carboxypeptidase</fullName>
            <ecNumber evidence="3">3.4.16.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002843</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S13 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.4" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301173.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002843"/>
    <dbReference type="MEROPS" id="S13.001"/>
    <dbReference type="EnsemblBacteria" id="EEZ41811">
        <property type="protein sequence ID" value="EEZ41811"/>
        <property type="gene ID" value="VDA_002843"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2027">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="720131at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009002">
        <property type="term" value="F:serine-type D-Ala-D-Ala carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000667">
        <property type="entry name" value="Peptidase_S13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30023">
        <property type="entry name" value="PTHR30023"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02113">
        <property type="entry name" value="Peptidase_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00922">
        <property type="entry name" value="DADACBPTASE3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00666">
        <property type="entry name" value="PBP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019871" evidence="2">
        <location>
            <begin position="20"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="464" mass="51469" checksum="59046EED78E167A1" modified="2010-01-19" version="1">MFKQLLCVSLLATSLPTLAAFNPQAAIAKLPQGHDLALLIKDPATGKIIYQQRTDNLQAPASTQKTITALAAKLYLGDNFRFYTDVETKGKDIIFNFSGDPTFSRTDLRELLSQIKAKGYKSIQGNIYLNGGHFTGYERGIGWPWDILGSCYSAPSSSITLEHNCVQGALYTNKGIGNKARINVPSHQPIQVTSTATIVTPSQKKAQFCQLDLISNPNNSYQVSGCSLAYKEPMPLKFAVQNTTKYTMAVMRQELKRAGISFKGQIYRNDTIKGQRIARNSSKPMSELLDIMLKRSDNLFADNIAKTIGAKYYQQPGSYNNGVAAIKEILKTKANIDLSDTIMVDGSGLSRNNRLSANDLMQVITYIYKHKNLKLFDDFPVAGESGTLRYRKSMRAGELKGKVIAKSGSLFATYNLAGMIKTKSGKPLLFIQLVTDYHPINKTKGLPPISQFEQKLYQSLYQQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZZ2</accession>
    <name>D0YZZ2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sodium-dependent phosphate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_002855</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301205.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002855"/>
    <dbReference type="EnsemblBacteria" id="EEZ41823">
        <property type="protein sequence ID" value="EEZ41823"/>
        <property type="gene ID" value="VDA_002855"/>
    </dbReference>
    <dbReference type="GeneID" id="57340856"/>
    <dbReference type="eggNOG" id="COG1283">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1341748at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015114">
        <property type="term" value="F:phosphate ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005436">
        <property type="term" value="F:sodium:phosphate symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044341">
        <property type="term" value="P:sodium-dependent phosphate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003841">
        <property type="entry name" value="Na/Pi_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030147">
        <property type="entry name" value="NptA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10010">
        <property type="entry name" value="PTHR10010"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10010:SF46">
        <property type="entry name" value="PTHR10010:SF46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02690">
        <property type="entry name" value="Na_Pi_cotrans"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="203"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="285"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="314"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="359"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="381" mass="40192" checksum="891F666B721273D4" modified="2010-01-19" version="1">MTTQATTAAKSNSSMRWVRWANLAFMLYVLLVAVSMVSSGFKWSVGEQAKTLFEFASHPVAGLMIGLVATALIQSSSTVTSIIVGLVAGGLPVETAIPMVMGANIGTTVTNTLVSLGHMRCKEEFRRAFASATVHDFFNLLAVAIFLPLEMMFGLLDKISSWLVSPFLGTGNMSMKGFDFMKPLTQPAIDLVKTPLETFGNNIGGALLIVIGISLIFLSITAMGKLMRSLMVGRAKEMLQHAIGRGPLHGIASGTVVTILVQSSSTTTSLMVPLVGTGVLKVRDVYPFTLGANIGTCITALLAATAVSGPNAVFALQIALVHLAFNVMATVVIFGIPFLREIPLKCAEFLSELATKNKAAVAGYLGLVFIAIPGSILAFTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z085</accession>
    <name>D0Z085_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Multifunctional CCA protein</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="11">CCA-adding enzyme</fullName>
                <ecNumber evidence="11">2.7.7.72</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="11">CCA tRNA nucleotidyltransferase</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="11">tRNA CCA-pyrophosphorylase</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="11">tRNA adenylyl-/cytidylyl-transferase</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="11">tRNA nucleotidyltransferase</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="11">tRNA-NT</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="11">2'-nucleotidase</fullName>
                <ecNumber evidence="11">3.1.3.-</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="11">2',3'-cyclic phosphodiesterase</fullName>
                <ecNumber evidence="11">3.1.4.-</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="11">Phosphatase</fullName>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="11" type="primary">cca</name>
        <name evidence="13" type="ORF">VDA_002948</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a tRNA precursor + ATP + 2 CTP = a tRNA with a 3' CCA end + 3 diphosphate</text>
            <dbReference type="Rhea" id="RHEA:14433"/>
            <dbReference type="Rhea" id="RHEA-COMP:10465"/>
            <dbReference type="Rhea" id="RHEA-COMP:10468"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:74896"/>
            <dbReference type="ChEBI" id="CHEBI:83071"/>
            <dbReference type="EC" id="2.7.7.72"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="11">Magnesium is required for nucleotidyltransferase activity.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
        </cofactor>
        <text evidence="11">Nickel for phosphatase activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Monomer. Can also form homodimers and oligomers.</text>
    </comment>
    <comment type="domain">
        <text evidence="11">Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="11">A single active site specifically recognizes both ATP and CTP and is responsible for their addition.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.72" evidence="11"/>
    <dbReference type="EC" id="3.1.3.-" evidence="11"/>
    <dbReference type="EC" id="3.1.4.-" evidence="11"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301405.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002948"/>
    <dbReference type="EnsemblBacteria" id="EEZ41916">
        <property type="protein sequence ID" value="EEZ41916"/>
        <property type="gene ID" value="VDA_002948"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0617">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2018439at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052929">
        <property type="term" value="F:ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052928">
        <property type="term" value="F:CTP:3'-cytidine-tRNA cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052927">
        <property type="term" value="F:CTP:tRNA cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004112">
        <property type="term" value="F:cyclic-nucleotide phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016437">
        <property type="term" value="F:tRNA cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042245">
        <property type="term" value="P:RNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001680">
        <property type="term" value="P:tRNA 3'-terminal CCA addition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05398">
        <property type="entry name" value="NT_ClassII-CCAase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01261">
        <property type="entry name" value="CCA_bact_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01262">
        <property type="entry name" value="CCA_bact_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012006">
        <property type="entry name" value="CCA_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002646">
        <property type="entry name" value="PolA_pol_head_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032828">
        <property type="entry name" value="PolyA_RNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01743">
        <property type="entry name" value="PolyA_pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12627">
        <property type="entry name" value="PolyA_pol_RNAbd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000813">
        <property type="entry name" value="CCA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="1 11" id="KW-0533">Nickel</keyword>
    <keyword evidence="6 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 11 13" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0692">RNA repair</keyword>
    <keyword evidence="10 11" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 11 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 11" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="HD" evidence="12">
        <location>
            <begin position="228"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="8"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="11"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="21"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="23"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="91"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="137"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ41916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="410" mass="45916" checksum="E806F2A73FF61D2D" modified="2010-01-19" version="1">MQVYLVGGAVRDALLQLPIVDKDWVVVGSTPEQMLAQGFEQVGTDFPVFLHPKTKQEHALARTERKSGRGYTGFICDFTPDVTLEQDLIRRDLTINAIAQAKDGTLIDPYGGQQDLEHRILRHVSPAFVEDPLRVLRVARFAARFAHMGFTVAAETMALMQEMVISGELAALTPERVWKEWEKSLSSQNPEIFLTVLRQCGALQVVMPEIDALFGIPQPEKWHPEIDCGIHTLLVAKQAAQLSQDKTIRFAAQLHDLGKALSPVEDLPHHKTHCLDGLKPIKALCQRLRVPNDYRDCALMVCAQHTKVHHAFEMKASTFVKIFDQIDAWRKPERISQLAICCRADARGRTGHEEDAYLQADILEQTFLAAQGVEVKPIVAEGYKGIEIKEQLALRRIDAVALTLTALRSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0F1</accession>
    <name>D0Z0F1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">tRNA-dihydrouridine(20/20a) synthase</fullName>
            <ecNumber evidence="6">1.3.1.91</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">U20-specific dihydrouridine synthase</fullName>
            <shortName evidence="6">U20-specific Dus</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">tRNA-dihydrouridine synthase A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">dusA</name>
        <name evidence="10" type="ORF">VDA_003015</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>5,6-dihydrouridine(20) in tRNA + NAD(+) = H(+) + NADH + uridine(20) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:53340"/>
            <dbReference type="Rhea" id="RHEA-COMP:13533"/>
            <dbReference type="Rhea" id="RHEA-COMP:13534"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.91"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>5,6-dihydrouridine(20) in tRNA + NADP(+) = H(+) + NADPH + uridine(20) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:53336"/>
            <dbReference type="Rhea" id="RHEA-COMP:13533"/>
            <dbReference type="Rhea" id="RHEA-COMP:13534"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.91"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>5,6-dihydrouridine(20a) in tRNA + NAD(+) = H(+) + NADH + uridine(20a) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:53348"/>
            <dbReference type="Rhea" id="RHEA-COMP:13535"/>
            <dbReference type="Rhea" id="RHEA-COMP:13536"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>5,6-dihydrouridine(20a) in tRNA + NADP(+) = H(+) + NADPH + uridine(20a) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:53344"/>
            <dbReference type="Rhea" id="RHEA-COMP:13535"/>
            <dbReference type="Rhea" id="RHEA-COMP:13536"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6 7">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the Dus family. DusA subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the dus family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.91" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003015"/>
    <dbReference type="EnsemblBacteria" id="EEZ41982">
        <property type="protein sequence ID" value="EEZ41982"/>
        <property type="gene ID" value="VDA_003015"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0042">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102264">
        <property type="term" value="F:tRNA-dihydrouridine20 synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02801">
        <property type="entry name" value="DUS_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02041">
        <property type="entry name" value="DusA_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035587">
        <property type="entry name" value="DUS-like_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001269">
        <property type="entry name" value="DUS_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004653">
        <property type="entry name" value="DusA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018517">
        <property type="entry name" value="tRNA_hU_synthase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42907">
        <property type="entry name" value="PTHR42907"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01207">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006621">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00742">
        <property type="entry name" value="yjbN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01136">
        <property type="entry name" value="UPF0034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6 7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 6 7" id="KW-0288">FMN</keyword>
    <keyword evidence="6" id="KW-0521">NADP</keyword>
    <keyword evidence="5 6 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 6 7" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="6" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Dus" evidence="9">
        <location>
            <begin position="1"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6 8">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="169"/>
            <end position="171"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="191"/>
            <end position="192"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="site" description="Interacts with tRNA" evidence="6">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <feature type="site" description="Interacts with tRNA; defines subfamily-specific binding signature" evidence="6">
        <location>
            <position position="141"/>
        </location>
    </feature>
    <feature type="site" description="Interacts with tRNA" evidence="6">
        <location>
            <position position="144"/>
        </location>
    </feature>
    <feature type="site" description="Interacts with tRNA; defines subfamily-specific binding signature" evidence="6">
        <location>
            <position position="257"/>
        </location>
    </feature>
    <feature type="site" description="Interacts with tRNA; defines subfamily-specific binding signature" evidence="6">
        <location>
            <position position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR006621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR006621-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ41982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="290" mass="32450" checksum="F0C23321CF7ED736" modified="2010-01-19" version="1">MVTTGAIIHGKGDFLAYNEEEHPLVLQLGGSNPADLARCAKLAQERGYDEINLNVGCPSDRVQNGMFGACLMGEAELVAHCVAAMREVVDIPVTVKTRIGIDEQDSYEFLTDFIGTVAEKGGCDNFTIHARKAWLKGLSPKENREIPPLDYPRVYQLKRDFPELTMGINGGIKTFEEMEEHLQHMDGVMVGREAYQSPYLMAEVDQRLFGSTKPVMKRREVVEAMYPYIEQQLAQGSYLGHITRHMLGLFQNMPGARQWRRHISENAHKPGSGIEVLQQALAKIPAHLDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0J4</accession>
    <name>D0Z0J4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_003058</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301715.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003058"/>
    <dbReference type="EnsemblBacteria" id="EEZ42025">
        <property type="protein sequence ID" value="EEZ42025"/>
        <property type="gene ID" value="VDA_003058"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2019">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ42025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="173" mass="19388" checksum="D28D819793723680" modified="2010-01-19" version="1">MATTIFISGIHGVGKTTLCNKITNHLGFRHYSCSDLIKQNSDYVETSKKIDNASRNQEVLLKAIENIKDKVYLLDGHFCLIDKLENVIQLDQSVFKSIAPKAIVNICCETSIIRERLINRDGKALSLTKLNELQSAEKTVSAEVAETLNIPYFVYTSSEPVDELITLLKQITL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0Q1</accession>
    <name>D0Z0Q1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Type II secretion system protein L</fullName>
            <shortName evidence="11">T2SS protein L</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">VDA_003115</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the GSP L family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301905.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003115"/>
    <dbReference type="EnsemblBacteria" id="EEZ42082">
        <property type="protein sequence ID" value="EEZ42082"/>
        <property type="gene ID" value="VDA_003115"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3297">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1819441at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009276">
        <property type="term" value="C:Gram-negative-bacterium-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024230">
        <property type="entry name" value="GspL_cyto_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025691">
        <property type="entry name" value="GspL_pp_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007812">
        <property type="entry name" value="T2SS_protein-GspL"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12693">
        <property type="entry name" value="GspL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05134">
        <property type="entry name" value="T2SSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015761">
        <property type="entry name" value="Protein_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01709">
        <property type="entry name" value="typeII_sec_gspL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 11" id="KW-0813">Transport</keyword>
    <feature type="domain" description="T2SSL" evidence="13">
        <location>
            <begin position="9"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="GspL_C" evidence="14">
        <location>
            <begin position="278"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="299"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR015761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF05134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF12693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEZ42082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="437" mass="49491" checksum="4889E58EEA70A8C7" modified="2010-01-19" version="1">MEESVSEFLTIRLSSQSTSPVQWLVWSPTEREVIASGQLPDSSHLGDLTEYAAQRPVYVVVPTSEMLLTQVTIPAGSSRQLSAVLPYLLEEELAQDVESLHVQLLKREKDIASVAVVEHSKMAYWLEQFKQHHFEVRKLLPDSLCLPLFNDGYSAAQLEQQWLIRQSETLGINVEISWLDAWLSAQKAPIVLTKDEQDESTEESAAEGEIIATTEAIAAQDEDLSQVIIHHYTPAPEVQLGRWRAETPELVMQLLAQGAESSKLNLLSGAYKPQAAWRKHLLPWRKVAIAAGLVLTALVAEHVIAVNQMENQAQAYRTESERIFRQVLPQFKRIPSQSYLRNQMKRAVASMGGEQQQGLLTWLLELQPMLKQVSQMQFTNFKYDQKRGELRIQANSTDFQHFEKLRTLLAKDFTVEQGQLSKEDGRVNGAFVLRRHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0Q3</accession>
    <name>D0Z0Q3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Type II secretion system protein J</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">VDA_003117</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the GSP J family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301910.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003117"/>
    <dbReference type="EnsemblBacteria" id="EEZ42084">
        <property type="protein sequence ID" value="EEZ42084"/>
        <property type="gene ID" value="VDA_003117"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4795">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1213602at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010055">
        <property type="entry name" value="T2SS_protein-GspJ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11612">
        <property type="entry name" value="T2SSJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01711">
        <property type="entry name" value="gspJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ42084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="218" mass="24937" checksum="A49683C12596369B" modified="2010-01-19" version="1">MSRINNLHSARNKGFTLLEVLVAIGVFAMLSLSAYQVLNGVQRSNVQSQEHNQRISEIQRAMIIMGNDFSQIVARQTRSNDEEPSKKLVESGEYLLDSSSQGILFVRDGWQNPEAMFPRGDVTKVGYRIVDDNLERVWFRYPDNTAGTEPLVKVILPNVTEMKLEFYTNKRWIKNWDSEGKLPDGIKVTLKLKDFGDIDRVFVLPKSELENEQNKAES</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0T8</accession>
    <name>D0Z0T8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">2-haloalkanoic acid dehalogenase</fullName>
            <ecNumber evidence="1">3.8.1.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_003152</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.8.1.2" evidence="1"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302017.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003152"/>
    <dbReference type="EnsemblBacteria" id="EEZ42119">
        <property type="protein sequence ID" value="EEZ42119"/>
        <property type="gene ID" value="VDA_003152"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1011">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1204073at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018784">
        <property type="term" value="F:(S)-2-haloacid dehalogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00413">
        <property type="entry name" value="HADHALOGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ42119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="250" mass="28272" checksum="D05866A4C585B2CB" modified="2010-01-19" version="1">MQQLRLENSLNGIKALSFDLDDTLYDNREVIVRAEQAMHQWLAEFDERFLLFRDGFWPQLKQRLALADPWLKHDVTLWRYQSIKVALMQLGYREAAAALAADRAVEHVLAVRNQVDVPPLTHQLLTQLSAHFPLVAITNGNVDIDKIGLGTYFQHRFCAGPDGLAKPDSNLFDKAVHALQVAPEQILHVGDHPISDIQGAQQAGFKTCWFNDKGRDFRALSSDMKPDIEIHQLDELLPLVAMSSVNESIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0U6</accession>
    <name>D0Z0U6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Porphobilinogen deaminase</fullName>
            <shortName evidence="8">PBG</shortName>
            <ecNumber evidence="8">2.5.1.61</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Hydroxymethylbilane synthase</fullName>
            <shortName evidence="8">HMBS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Pre-uroporphyrinogen synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">hemC</name>
        <name evidence="11" type="ORF">VDA_003160</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 8">Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>H2O + 4 porphobilinogen = hydroxymethylbilane + 4 NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:13185"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57845"/>
            <dbReference type="ChEBI" id="CHEBI:58126"/>
            <dbReference type="EC" id="2.5.1.61"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>dipyrromethane</name>
            <dbReference type="ChEBI" id="CHEBI:60342"/>
        </cofactor>
        <text evidence="8">Binds 1 dipyrromethane group covalently.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 2/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 8">Monomer.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="8">The porphobilinogen subunits are added to the dipyrromethane group.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 8">Belongs to the HMBS family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.61" evidence="8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003160"/>
    <dbReference type="EnsemblBacteria" id="EEZ42127">
        <property type="protein sequence ID" value="EEZ42127"/>
        <property type="gene ID" value="VDA_003160"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0181">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00319"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004418">
        <property type="term" value="F:hydroxymethylbilane synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018160">
        <property type="term" value="P:peptidyl-pyrromethane cofactor linkage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00260">
        <property type="entry name" value="Porphobil_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000860">
        <property type="entry name" value="HemC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022419">
        <property type="entry name" value="Porphobilin_deaminase_cofac_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022417">
        <property type="entry name" value="Porphobilin_deaminase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022418">
        <property type="entry name" value="Porphobilinogen_deaminase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036803">
        <property type="entry name" value="Porphobilinogen_deaminase_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11557">
        <property type="entry name" value="PTHR11557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01379">
        <property type="entry name" value="Porphobil_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03900">
        <property type="entry name" value="Porphobil_deamC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001438">
        <property type="entry name" value="4pyrrol_synth_OHMeBilane_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00151">
        <property type="entry name" value="PORPHBDMNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54782">
        <property type="entry name" value="SSF54782"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00212">
        <property type="entry name" value="hemC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00533">
        <property type="entry name" value="PORPHOBILINOGEN_DEAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Porphobil_deam" evidence="9">
        <location>
            <begin position="1"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="Porphobil_deamC" evidence="10">
        <location>
            <begin position="210"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="modified residue" description="S-(dipyrrolylmethanemethyl)cysteine" evidence="8">
        <location>
            <position position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ42127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="294" mass="32136" checksum="B449958CF308985E" modified="2010-01-19" version="1">MWQAEFVKAELEKAHPGLVVELVPMVTKGDVILDTPLAKVGGKGLFVKELEVAMLEGRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNRYNSLEELPQGSIVGTSSLRRQCQLRSQRPDLIVKDLRGNVNTRLRKLDDGEYDAIILACAGLKRLKMDDRIRAAIAPETSLPAVGQGAVGIECRLDDTRVRDLLAALNHQETATRVLCERAMNNRLQGGCQVPIGSYAELQGDQIWLRALVGEPDGSQIVRGEISGSANDAEALGTQLAEQLLADGAKPILERLYQEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z176</accession>
    <name>D0Z176_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aldehyde dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_003290</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3 6">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003290"/>
    <dbReference type="EnsemblBacteria" id="EEZ42257">
        <property type="protein sequence ID" value="EEZ42257"/>
        <property type="gene ID" value="VDA_003290"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1012">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006081">
        <property type="term" value="P:cellular aldehyde metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012394">
        <property type="entry name" value="Aldehyde_DH_NAD(P)"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43570">
        <property type="entry name" value="PTHR43570"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036492">
        <property type="entry name" value="ALDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="8">
        <location>
            <begin position="12"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="active site" evidence="4 5">
        <location>
            <position position="232"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR036492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR036492-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ42257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="486" mass="54523" checksum="F6749B510E7B1EDB" modified="2010-01-19" version="1">MTAVQSTQTSDPTQKTKENDERLDLNQLFTAQQQAYASEPYLELTQRLALLKQLKHQLLAYKKPLCQALHQDYGNRSQYDTLLSDILPCVQNINYTIKHLKRWLKPSKRHAGLLLMPAKLQVHYQPLGVVGIIVPWNFPVMLSIGPLIAAIAAGNRAMLKLSEFTPQTNQVLRELLAKVFTPDYVAVVEGEADIAQAFSQLPFHHILFTGSTAVGHHVMHAAADNLTPVTLELGGKSPVVIAPDVPLELAVERLIFGKCLNAGQICVAPDYVLLPQEKIEEFISLFKQKYRTLYPHGITGQDFASIINQRQFDRLYHLLQDAEAQGARIHPCHEPAIDFEGRRLAPHLITNVSDQMAVMEQEIFGPLLPLIPYQSQQQAIEFINQRPRPLALYVMSFDPSWQQTFIYHTHSGGIAINDTVFHVAADDAPFGGIGPSGMGHYHGHEGFLTFSKAKTVLTKGKFSSGKFIFPPYGRWLQRLILSIFLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z188</accession>
    <name>D0Z188_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 8">Ribosomal RNA small subunit methyltransferase D</fullName>
            <ecNumber evidence="4 8">2.1.1.171</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_003302</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 8">Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>guanosine(966) in 16S rRNA + S-adenosyl-L-methionine = H(+) + N(2)-methylguanosine(966) in 16S rRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:23548"/>
            <dbReference type="Rhea" id="RHEA-COMP:10211"/>
            <dbReference type="Rhea" id="RHEA-COMP:10212"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74481"/>
            <dbReference type="EC" id="2.1.1.171"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the methyltransferase superfamily. RsmD family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.171" evidence="4 8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302441.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003302"/>
    <dbReference type="EnsemblBacteria" id="EEZ42269">
        <property type="protein sequence ID" value="EEZ42269"/>
        <property type="gene ID" value="VDA_003302"/>
    </dbReference>
    <dbReference type="GeneID" id="57340258"/>
    <dbReference type="eggNOG" id="COG0742">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1827334at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052913">
        <property type="term" value="F:16S rRNA (guanine(966)-N(2))-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004398">
        <property type="entry name" value="RNA_MeTrfase_RsmD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004553">
        <property type="entry name" value="CHP00095"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00095">
        <property type="entry name" value="TIGR00095"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="8" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="7 8 9" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR004553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ42269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="202" mass="22829" checksum="443B1E7CC9FB6ED3" modified="2010-01-19" version="1">MTKRRQQTGKKPQNNRQSGFVRIISGQWRGRKLPVHDVEGLRPTTDRVKETLFNWLAQDIYQAKCLDLFAGSGSLSFEALSRGAESLTMIELDQKAAAQLKQNLTAIGATNATLHNTNSVNFLNQAGTPHDLVFIDPPFRKDLIQQVIAALEANHWLSPNALIYIEAEKELGSIDVPPSWHLYREKTAGQVCYRLFIREEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1A0</accession>
    <name>D0Z1A0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 8">Glycerol-3-phosphate acyltransferase</fullName>
            <shortName evidence="8">GPAT</shortName>
            <ecNumber evidence="5 8">2.3.1.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">plsB</name>
        <name evidence="10" type="ORF">VDA_003314</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>an acyl-CoA + sn-glycerol 3-phosphate = a 1-acyl-sn-glycero-3-phosphate + CoA</text>
            <dbReference type="Rhea" id="RHEA:15325"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:57970"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="EC" id="2.3.1.15"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 1/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Peripheral membrane protein</topology>
            <orientation evidence="8">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 8">Belongs to the GPAT/DAPAT family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.15" evidence="5 8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302472.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003314"/>
    <dbReference type="EnsemblBacteria" id="EEZ42281">
        <property type="protein sequence ID" value="EEZ42281"/>
        <property type="gene ID" value="VDA_003314"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2937">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="580383at2"/>
    <dbReference type="UniPathway" id="UPA00557">
        <property type="reaction ID" value="UER00612"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004366">
        <property type="term" value="F:glycerol-3-phosphate O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102420">
        <property type="term" value="F:sn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016024">
        <property type="term" value="P:CDP-diacylglycerol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd07993">
        <property type="entry name" value="LPLAT_DHAPAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00393">
        <property type="entry name" value="Glyc3P_acyltrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022284">
        <property type="entry name" value="GPAT/DHAPAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041728">
        <property type="entry name" value="GPAT/DHAPAT_LPLAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045520">
        <property type="entry name" value="GPAT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028354">
        <property type="entry name" value="GPAT_PlsB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12563">
        <property type="entry name" value="PTHR12563"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19277">
        <property type="entry name" value="GPAT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500064">
        <property type="entry name" value="GPAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000437">
        <property type="entry name" value="GPAT_DHAPAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03703">
        <property type="entry name" value="plsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PlsC" evidence="9">
        <location>
            <begin position="300"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="HXXXXD motif" evidence="8">
        <location>
            <begin position="305"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ42281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="816" mass="92422" checksum="772A65F6AFCF6DDE" modified="2010-01-19" version="1">MSTWQKISRQLLRLPLSLLVKTNSIPSDPVTDLELDLERPIVYILPFRSTTDLMTLRSSTQELGLPDPLSPLEIGDKQLARYVFVAKGPSIFGSSSDLPAESVELFTELLELHKQNPELNIQLVPASVLWGRKPGKEKETGPILRPLNGPKKFLAILAQGRDCLVRLSTPVSLRYMADNHGTDDAIAHKLARVAKIHFSRQQIAASGPRLPDRHELFKRLLASKAIEKVVTEEAKSRDVPVEKVRKEAIEMMEEIAANFSYSLIKHGDSFLGWLWNKLYQGLNIHNAQRVRRLAQDGHEIVYVPCHRSHMDYLLLSYVLYNEGLVPPHIAAGINLNFFPAGPIFRRGGAFFIRRSFRGDRLYSTVFREYLAELFAKGYSVEYFSEGGRSRTGRLLPAKTGMLSMTIQAMLRGLKRPVTLVPVYIGYEHVMEVGTYAKELQGKRKEKENVGQVIRTIRKLQNLGQGYVNFGEPIPLNQYLNDNVPNWHQDIDPIEPSKPQWLNPVVNDLAIKMMTHINDAAATNALTLCALALLSSYQRALSREELEEQIDCYLELLRNVPYSSQCTMPKESAKELVDHTLEMGKFIVDRDTLGDIISLDRKQSILMTYYRNNIIHLFALPSLIAHIVVSHQSLTNDEIHEQVELLYPFLKAELFLRYNKEELDPAIDNIIAELVRQGLLLNDGLNISMNEARIGPLQLLARTIKETLQRYAITLTLLRAEPEVIKSDLEQQSQMLAQRLSRIHGINAPEFFDKGVFSTLVKTLRAEGYLNDECHALTRPVENLTETLTALVSPEVKLTISAVMNHTPAPEQEEQVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1B0</accession>
    <name>D0Z1B0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protoheme IX farnesyltransferase</fullName>
            <ecNumber evidence="9">2.5.1.141</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Heme B farnesyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Heme O synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">cyoE</name>
        <name evidence="10" type="ORF">VDA_003324</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>(2E,6E)-farnesyl diphosphate + H2O + heme b = diphosphate + Fe(II)-heme o</text>
            <dbReference type="Rhea" id="RHEA:28070"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <dbReference type="ChEBI" id="CHEBI:60530"/>
            <dbReference type="ChEBI" id="CHEBI:175763"/>
            <dbReference type="EC" id="2.5.1.141"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="9">Porphyrin-containing compound metabolism; heme O biosynthesis; heme O from protoheme: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="9">Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.141" evidence="9"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302493.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003324"/>
    <dbReference type="EnsemblBacteria" id="EEZ42291">
        <property type="protein sequence ID" value="EEZ42291"/>
        <property type="gene ID" value="VDA_003324"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0109">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1875497at2"/>
    <dbReference type="UniPathway" id="UPA00834">
        <property type="reaction ID" value="UER00712"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008495">
        <property type="term" value="F:protoheme IX farnesyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048034">
        <property type="term" value="P:heme O biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd13957">
        <property type="entry name" value="PT_UbiA_Cox10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00154">
        <property type="entry name" value="CyoE_CtaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006369">
        <property type="entry name" value="Protohaem_IX_farnesylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030470">
        <property type="entry name" value="UbiA_prenylTrfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43448">
        <property type="entry name" value="PTHR43448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01473">
        <property type="entry name" value="cyoE_ctaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00943">
        <property type="entry name" value="UBIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="55"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="97"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="126"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="150"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="175"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="219"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="246"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="276"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ42291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="301" mass="33281" checksum="CDE1267F545A03F8" modified="2010-01-19" version="1">MAKLLTVATTTSRPRVAVWQDYLTMTKPKVVAMLVLTALVGMCLAVPGLPPWKNLVLGLLGIGLQSSAAAAFNHILDRHFDAKMARTYHRPLAKGRIETWKAVLFATTLMVSGFYCLWLLNALTAWLTFASLVGYALVYTVWLKHATPQNIVIGGIAGAAPPLLGWTAITGSVDPHALLLVMLIFTWTPPHFWALAIHRRDDYAKAKIPMLPVTHGIEFTKTMVLLYTVILFAVGLLPWLTGMCGWVYLLASSVLNLGFVGYALKLKFADSEGHAWATFKYSIWHLLALFVVLLLDHWLSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1B1</accession>
    <name>D0Z1B1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Multidrug resistance protein NorM</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Na(+)/drug antiporter</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_003325</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003325"/>
    <dbReference type="EnsemblBacteria" id="EEZ42292">
        <property type="protein sequence ID" value="EEZ42292"/>
        <property type="gene ID" value="VDA_003325"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0534">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13136">
        <property type="entry name" value="MATE_DinF_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044644">
        <property type="entry name" value="DinF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42893">
        <property type="entry name" value="PTHR42893"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006603">
        <property type="entry name" value="DinF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="24"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="55"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="147"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="175"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="204"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="255"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="286"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="330"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="366"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="400"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="422"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00030855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ42292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="455" mass="50066" checksum="A1A3B1D9956462A3" modified="2010-01-19" version="1">MASLPTKEVCVLAALKDKSLHYQVFALALPMVLSNITVPLLGLVDAAVIGHLEHAWYLGGVAVGGTMINVTFWLLGFLRMATTGINAQAVGRQDRSGQATIFVQGIGLAWLLALLLIVFHQPVSQLIFHFSDASAQVKEYAGQYFSIRIWGAPAALANLVIMGWLLGAQNARAPMWLLIVTNLVNIVLDVFFVLGLHWKVQGAASASVIADYSGMLLGFYFVARHWQQQQLPPLKEKLSALRYGMGRLLKLNRDIFLRSLCLQAAFTFMTFQGATLGDNVVAANAVLMSFLMLVSYAMDGFAYAMEALVGKAVGAKDKQELGRYLTGTTFWSLMISLLLTLAFVCFGSSIINLISSIPQVQQQAAIYLPWLTAVPLVSMWCFLLDGIFVGATRGREMRNSMFVAICTFFVVWWALSSYGNHALWAAMLAFMAMRGLTLAVVFAYQWRKNIFLSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1C4</accession>
    <name>D0Z1C4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein YicC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_003338</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003338"/>
    <dbReference type="EnsemblBacteria" id="EEZ42305">
        <property type="protein sequence ID" value="EEZ42305"/>
        <property type="gene ID" value="VDA_003338"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1561">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005229">
        <property type="entry name" value="CHP00255"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013551">
        <property type="entry name" value="DUF1732"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013527">
        <property type="entry name" value="YicC-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30636">
        <property type="entry name" value="PTHR30636"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08340">
        <property type="entry name" value="DUF1732"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03755">
        <property type="entry name" value="YicC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00255">
        <property type="entry name" value="TIGR00255"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YicC_N" evidence="2">
        <location>
            <begin position="1"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1732" evidence="3">
        <location>
            <begin position="199"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="178"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ42305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="283" mass="32240" checksum="5C92268A9798341C" modified="2010-01-19" version="1">MTAYARREVKGDWGTAVWEIRSVNQRYLETYLRMPEQFRGLEPVLRERFRQRLARGKVECNLRFEANPAANTNLTINEALAKQVINAAKWVKDTSGEGSINPFQVLNWPGVMEAPEQDLDTINKDLLAGFDAAIDDFIAARASEGDNMRALIEQRLDAISAEAGKVRALMPEIMTWQRERIMSRLDEAKIELDANRLEQELVMLAQKSDVAEELDRLDSHVKETQKILKKGGACGRRLDFMMQEFNRESNTLASKSINTDVTAAAVELKVLIEQMREQIQNIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1E2</accession>
    <name>D0Z1E2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_003356</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302561.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003356"/>
    <dbReference type="EnsemblBacteria" id="EEZ42323">
        <property type="protein sequence ID" value="EEZ42323"/>
        <property type="gene ID" value="VDA_003356"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5032T52">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011122">
        <property type="entry name" value="WavE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07507">
        <property type="entry name" value="WavE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ42323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="321" mass="37334" checksum="57564EF3B559D9C1" modified="2010-01-19" version="1">MRQQTFEQISVVVQGPVQNYQGRTHHEEGITQRCLESIRTHLPGAKIILSTWPDQDLTGLSYDQLVISQDPGVNLVDGLPQFPKNYDRQLVSTQAGLAQVTTPYAIKLRSDNYLIGNDFVSIQQTFSKYESDQKLFNEKVVINSNLFRRTSHGRTVLMSPSDFFYFGTTEDLKKIWQLPLIAEQPIAEEMITIMKSASITSCTLEAEQFYCQIWLKALNPKTKVMQHRFDYTQKDIIAWERFLASNIIIADPETMGLGLRKISKRKLKRANEFSHIDWLKLYKKYCDHSITIPKNYHQWLLEIRRAFKLPLSNLSSRFKHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1E8</accession>
    <name>D0Z1E8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Lipid A biosynthesis myristoyltransferase</fullName>
            <ecNumber evidence="6">2.3.1.243</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Kdo(2)-lauroyl-lipid IV(A) myristoyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">lpxM</name>
        <name evidence="7" type="ORF">VDA_003362</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the transfer of myristate from myristoyl-acyl carrier protein (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2)-lipid A.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>dodecanoyl-(Kdo)2-lipid IVA + tetradecanoyl-[ACP] = alpha-Kdo-(2-&gt;4)-alpha-Kdo-(2-&gt;6)-lipid A + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:28438"/>
            <dbReference type="Rhea" id="RHEA-COMP:9648"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="ChEBI" id="CHEBI:58540"/>
            <dbReference type="ChEBI" id="CHEBI:61524"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78477"/>
            <dbReference type="EC" id="2.3.1.243"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Bacterial outer membrane biogenesis; lipopolysaccharide biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Glycolipid biosynthesis; KDO(2)-lipid A biosynthesis; KDO(2)-lipid A from CMP-3-deoxy-D-manno-octulosonate and lipid IV(A): step 4/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell inner membrane</location>
            <topology evidence="6">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the LpxL/LpxM/LpxP family. LpxM subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.243" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302571.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003362"/>
    <dbReference type="EnsemblBacteria" id="EEZ42329">
        <property type="protein sequence ID" value="EEZ42329"/>
        <property type="gene ID" value="VDA_003362"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1560">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1106624at2"/>
    <dbReference type="UniPathway" id="UPA00030"/>
    <dbReference type="UniPathway" id="UPA00360">
        <property type="reaction ID" value="UER00486"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009276">
        <property type="term" value="C:Gram-negative-bacterium-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019107">
        <property type="term" value="F:myristoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036104">
        <property type="term" value="P:Kdo2-lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009103">
        <property type="term" value="P:lipopolysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd07984">
        <property type="entry name" value="LPLAT_LABLAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01944">
        <property type="entry name" value="Lipid_A_LpxM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004960">
        <property type="entry name" value="LipA_acyltrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011921">
        <property type="entry name" value="Lipid_A_MsbB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30606">
        <property type="entry name" value="PTHR30606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03279">
        <property type="entry name" value="Lip_A_acyltrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF026649">
        <property type="entry name" value="MsbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02208">
        <property type="entry name" value="lipid_A_msbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2 6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1 6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0448">Lipopolysaccharide biosynthesis</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="24"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="HXXXXD motif" evidence="6">
        <location>
            <begin position="139"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ42329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="316" mass="36396" checksum="9A7E7B43F9BE0279" modified="2010-01-19" version="1">MLDHYDKQAYHPQFSWHFLHPKYWGTWLAVFFSALFCLLPHNARRALATLFAKQAIKIKKGANLRARVNLALCFPDKTEAEREEILLQNLITAGSFLLGFAALSMRNRQWLEDHTVIRGMDNLTSLTEQGQSVILLVPHTWAIDIPAVLLASRGLPVSAMAKKQKNEVSDWLMHKQRVQYGGRVYERSGGIKPFIKSIREGYLGYYLPDEDLGPEHSVFVDFFATKKATMSGLGRVAKLSRAKIVPLFSMYNSETGNYELDFYPALPFPTDSEEQDARMMNECIEQYVTERPEQYMWILRLLKTRPEGECNPYHKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1J6</accession>
    <name>D0Z1J6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DamX-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_003410</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302662.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003410"/>
    <dbReference type="EnsemblBacteria" id="EEZ42377">
        <property type="protein sequence ID" value="EEZ42377"/>
        <property type="gene ID" value="VDA_003410"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3266">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1213917at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042834">
        <property type="term" value="F:peptidoglycan binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007730">
        <property type="entry name" value="SPOR-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036680">
        <property type="entry name" value="SPOR-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13401">
        <property type="entry name" value="AAA_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05036">
        <property type="entry name" value="SPOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110997">
        <property type="entry name" value="SSF110997"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51724">
        <property type="entry name" value="SPOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="236"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="SPOR" evidence="3">
        <location>
            <begin position="412"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="347"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="348"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="391"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ42377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="502" mass="55842" checksum="AE87383C30F61D7F" modified="2010-01-19" version="1">MIGHDATTRLDLDSQIQFLSRLQFVTQFSSHLIQISGPFGAGKTELLHCYLEHFSPEQHQVLLSAEPDMSLTSVRTQLLQQLVPTKPFNEQDSLLQSVSHMLSSDRLHCLLVVDNAHYLSIPILAELWELVCHANQQADWQLNVLLFTEPDVIAQPLAKMTHGQSEIPLELEIAPLPANEVLQLIEHCYEQDLQKRRELKLRYQHSFAFPGQLDEDTQPPGEEVSMTASHQLSPRTGLLIGVLFALVVALLWLWPESKPSEDSAIDSSASQVMEGKELISSGEPTEDTAALPPEVTQEGLTVGRTDTDKRVVVPAQVVDAMMGDQALGLVGAQTHFSDAEINALDPANVHPSSVTSPQATTTPLSESEPISESVKPEPEQPAKSLDKSLKQHDTPQPISHNNQHSDKQILQQVNSRHYALQLAAVHSWQQAKQFVAKYGVTESAHIYQTERQGKAWFIVVIGDYSSATQAKRAKNQLSHEVQALKPWPKSYAQIQKEMNRVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1L9</accession>
    <name>D0Z1L9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_003433</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003433"/>
    <dbReference type="EnsemblBacteria" id="EEZ42400">
        <property type="protein sequence ID" value="EEZ42400"/>
        <property type="gene ID" value="VDA_003433"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2964">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039446">
        <property type="entry name" value="DauR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039445">
        <property type="entry name" value="DauR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013559">
        <property type="entry name" value="YheO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35568">
        <property type="entry name" value="PTHR35568"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13309">
        <property type="entry name" value="HTH_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08348">
        <property type="entry name" value="PAS_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAS_6" evidence="1">
        <location>
            <begin position="30"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="HTH_22" evidence="2">
        <location>
            <begin position="173"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ42400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="239" mass="26604" checksum="B2763800BCE53865" modified="2010-01-19" version="1">MSTENLNTELMVESDIIETRTFTEHDYIILRSYEAVVDGLAALIGPFCEIVLHSLADLNTSAIKIANGENTGRKVGSPITDLALRMLRDIEGSERNFSRAYFTRAKGGALMKSITIAIRNGDNNIVGLLCINVNLDAPFSQILQSFMPTDEAKQAASSVNFASDVDELVDQTVERTIEEINADKAVSNNAKNRQIVMELFDKGIFDIKDAINRVADRLNISKHTVYLYIRQRKTEDGEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1R4</accession>
    <name>D0Z1R4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Homoserine O-succinyltransferase</fullName>
            <shortName evidence="4">HST</shortName>
            <ecNumber evidence="4">2.3.1.46</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Homoserine transsuccinylase</fullName>
            <shortName evidence="4">HTS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">metAS</name>
        <name evidence="6" type="ORF">VDA_003478</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>L-homoserine + succinyl-CoA = CoA + O-succinyl-L-homoserine</text>
            <dbReference type="Rhea" id="RHEA:22008"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:57476"/>
            <dbReference type="ChEBI" id="CHEBI:57661"/>
            <dbReference type="EC" id="2.3.1.46"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; O-succinyl-L-homoserine from L-homoserine: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the MetA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.46" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303559.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003478"/>
    <dbReference type="EnsemblBacteria" id="EEZ42445">
        <property type="protein sequence ID" value="EEZ42445"/>
        <property type="gene ID" value="VDA_003478"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1897">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1601420at2"/>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00075"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004414">
        <property type="term" value="F:homoserine O-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008899">
        <property type="term" value="F:homoserine O-succinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019281">
        <property type="term" value="P:L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03131">
        <property type="entry name" value="GATase1_HTS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00295">
        <property type="entry name" value="MetA_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005697">
        <property type="entry name" value="HST_MetA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033752">
        <property type="entry name" value="MetA_family"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20919">
        <property type="entry name" value="PTHR20919"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04204">
        <property type="entry name" value="HTS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000450">
        <property type="entry name" value="H_ser_succinyltr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01001">
        <property type="entry name" value="metA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 6" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="4 5">
        <location>
            <position position="142"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="235"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="237"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="249"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for acyl-CoA specificity" evidence="4">
        <location>
            <position position="111"/>
        </location>
    </feature>
    <feature type="site" description="Important for substrate specificity" evidence="4">
        <location>
            <position position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000450-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ42445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="313" mass="36306" checksum="80AD59DDF8C60EAB" modified="2010-01-19" version="1">MPIKIPDQLPATDILRSENIFVMTEARAASQGIRPLKVLLLNLMPKKIETETQFLRLLSNSPLQVDIELLRIDNRPTKNTPQEHLDTFYRQFEMVKGRNFDGLIVTGAPLGLVQFEDVLYWEEIQIIMNWAKDHVTSTLFICWAAQAGLKLLYDLPKRTRKEKLSGVYQHQIHDHHHPLLRGFDDTFLAPHSRYADFSPTFLSQHTDLDILATSSIAGVYMAATPDKRNVFVTGHPEYEVDTLHNEYVRDVEQGLEPNLPLNYYPEDDPRNPPRASWRSHGHLLFSNWLNYCVYQQTPYDLDNFSEANFTRDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1S0</accession>
    <name>D0Z1S0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">UvrABC system protein A</fullName>
            <shortName evidence="13">UvrA protein</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Excinuclease ABC subunit A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">uvrA</name>
        <name evidence="16" type="ORF">VDA_003484</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Forms a heterotetramer with UvrB during the search for lesions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the ABC transporter superfamily. UvrA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303573.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003484"/>
    <dbReference type="EnsemblBacteria" id="EEZ42451">
        <property type="protein sequence ID" value="EEZ42451"/>
        <property type="gene ID" value="VDA_003484"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0178">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="152379at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009380">
        <property type="term" value="C:excinuclease repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009381">
        <property type="term" value="F:excinuclease ABC activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00205">
        <property type="entry name" value="UvrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004602">
        <property type="entry name" value="UvrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041552">
        <property type="entry name" value="UvrA_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041102">
        <property type="entry name" value="UvrA_inter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17755">
        <property type="entry name" value="UvrA_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17760">
        <property type="entry name" value="UvrA_inter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00630">
        <property type="entry name" value="uvra"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 13 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 13" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 13" id="KW-0228">DNA excision</keyword>
    <keyword evidence="12 13" id="KW-0234">DNA repair</keyword>
    <keyword evidence="11 13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10 13" id="KW-0267">Excision nuclease</keyword>
    <keyword evidence="2 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 13 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 13" id="KW-0677">Repeat</keyword>
    <keyword evidence="13" id="KW-0742">SOS response</keyword>
    <keyword evidence="8 13" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 13" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="ABC transporter" evidence="15">
        <location>
            <begin position="314"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="15">
        <location>
            <begin position="606"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="13">
        <location>
            <begin position="252"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="13">
        <location>
            <begin position="739"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="31"/>
            <end position="38"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <begin position="639"/>
            <end position="646"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EEZ42451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="941" mass="104061" checksum="113EB3D04A1960F1" modified="2010-01-19" version="1">MDKIEVRGARTHNLKNINLTIPRDKLIVITGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLSLMEKPDVDHIEGLSPAISIEQKSTSHNPRSTVGTITEVYDYLRLLYARVGEPRCPTHNVTLAAQTVSQMVDQVLSLPEGSKLMMLAPIIKERKGEHVKTLANLAAQGYIRARIDGEVCDLSDPPTLELHKKHTIEVVVDRFKVRDDLQQRLAESFETALELSGGNVVISPMDGDGEELVFSANFACPHCGYSMQELEPRLFSFNNPAGACGTCDGLGVQQYFDPERVVQNGELSLAGGAIRGWDKKNFYYFQMLKSLAEHYDFDVDAPFNSLSKKVQNVVLNGSGTTNIEFKYINDRGDITVRRHPFEGILNNMERRYHDTESNSVREDLAKFVSTKPCASCHGSRLRQEARHVFIHETNLPQICEMSINEALAFFTQLELTGQRAQIAEKVLKEIQERLSFLVNVGLNYLNLSRSADTLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLKTLTHLRDLGNTVIVVEHDEDAIRAADYIIDIGPGAGVHGGNIIAEGTLKDILKSKQSLTGQYLSGKKSIAVPEQRIPFDSKKTVKLLGATGNNLKNVDLEIPVGLFTCITGVSGSGKSTLINDTFFEIAHHKLNGATSGDPAPYKEIQDLEHFDKVIDIDQSPIGRTPRSNPATYTGIFTPIRELFAGTQESRSRGYKPGRFSFNVRGGRCEACQGDGVIKVEMHFLPDVYVPCDSCKGKRYNRETLEVRYKGKTIDEVLEMTVEDARKFFDPVPVIARKLQTLMDVGLSYIRLGQAATTLSGGEAQRVKLARELSKRDTGKTLYILDEPTTGLHFHDIQQLLTVLHQLRDRGNTIVVIEHNLDVIKTADWIVDLGPEGGSGGGQIIATGTPEQVAQVEGSHTARFLKPLLTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1Z0</accession>
    <name>D0Z1Z0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative outer membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001962</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001962"/>
    <dbReference type="EnsemblBacteria" id="EEZ40930">
        <property type="protein sequence ID" value="EEZ40930"/>
        <property type="gene ID" value="VDA_001962"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1538">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019323" evidence="2">
        <location>
            <begin position="26"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="544" mass="60360" checksum="B88A9139466C2EBE" modified="2010-01-19" version="1">MLKHSLRACMTILPLCSLTACSVLGPNFESLQPKAIPAQWQLVDQQDQADVALWWQQFNDPTLDHLVEMAAEQNLDLEAAGLRIIQARAALGISQGLQYPQVQQVSGNLAKAYQNEKSFDNAALSFDAGWELDVWGKYARGIESAEALMYASIASYRDIAVTITAEVARNYINYRTFQERILLSKRNIEIQQRVVHITQVQYDSGNVTELDVQQAKNQLYTTKAALPSLKIAMLQARNALAVLLGVLPSEVDALLGSDAIDKKIAVYDSRYAVGKKAALNGTDKYSLVPHIPKVDNQIDANLVMRRPDLQVAELQAHSQSAKIGLAETALYPSFSLLGSIGINSTVPSDRSFSFSDSLMLVAGPSFSWNIFQYGRVKNNIRLEDVRFQESLTNYNKKVLVAVQEVTNALESYDLYTEQKALRLQSVNSSIRAFNISMTQYENGQISFERLLNSVEKMTRSEDSYAQIKGNVANQVVALYKALGGGWQITSGKPLVADSTIETMRSRTDWGTSLDEDLVMPKADLPKQVVLPQLDPDKVPVEELN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z251</accession>
    <name>D0Z251_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative methyl-accepting chemotaxis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_001787</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the methyl-accepting chemotaxis (MCP) protein family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001787"/>
    <dbReference type="EnsemblBacteria" id="EEZ40755">
        <property type="protein sequence ID" value="EEZ40755"/>
        <property type="gene ID" value="VDA_001787"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0840">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004090">
        <property type="entry name" value="Chemotax_Me-accpt_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00260">
        <property type="entry name" value="CHEMTRNSDUCR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0807">Transducer</keyword>
    <feature type="domain" description="HAMP" evidence="7">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="5">
        <location>
            <begin position="45"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="6">
        <location>
            <begin position="232"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00029447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ40755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="317" mass="33963" checksum="57450193F900B68A" modified="2010-01-19" version="1">MRDVAQGNLAVRAHDDGDNEIAQLSSDVNRTVEQLYSTVDSMIRISEDVASAATELAAVMSQSEANAQLEQNEIDQVASAVNELSSTADNVSDNATTADSTAKQTDELAKAGLDIFEESNTASQQMSNTLNEAAGVVTQLKEQSEQISKVIEVIRGISEQTNLLALNAAIEAARAGESGRGFAVVADEVRMLAARTQDSTQEIQSIIEELQTQSGHANDSMQASLEMLVRNQVLAQQANDALVGITESVIHISDINTQVATAAEQQSQVTQDINRNVNNMSEIVNQNVTGISQSASASHELSKLAEQQKQQLSFFKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z260</accession>
    <name>D0Z260_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glucose-6-phosphate 1-dehydrogenase</fullName>
            <shortName evidence="5">G6PD</shortName>
            <ecNumber evidence="5">1.1.1.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">zwf</name>
        <name evidence="9" type="ORF">VDA_001796</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>D-glucose 6-phosphate + NADP(+) = 6-phospho-D-glucono-1,5-lactone + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:15841"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57955"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:61548"/>
            <dbReference type="EC" id="1.1.1.49"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the glucose-6-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.49" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298716.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001796"/>
    <dbReference type="EnsemblBacteria" id="EEZ40764">
        <property type="protein sequence ID" value="EEZ40764"/>
        <property type="gene ID" value="VDA_001796"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0364">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1153269at2"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00408"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004345">
        <property type="term" value="F:glucose-6-phosphate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00966">
        <property type="entry name" value="G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001282">
        <property type="entry name" value="G6P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019796">
        <property type="entry name" value="G6P_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022675">
        <property type="entry name" value="G6P_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022674">
        <property type="entry name" value="G6P_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23429">
        <property type="entry name" value="PTHR23429"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02781">
        <property type="entry name" value="G6PD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00479">
        <property type="entry name" value="G6PD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000110">
        <property type="entry name" value="G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00079">
        <property type="entry name" value="G6PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00871">
        <property type="entry name" value="zwf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00069">
        <property type="entry name" value="G6P_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="1 5" id="KW-0313">Glucose metabolism</keyword>
    <keyword evidence="2 5" id="KW-0521">NADP</keyword>
    <keyword evidence="3 5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G6PD_N" evidence="7">
        <location>
            <begin position="10"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="G6PD_C" evidence="8">
        <location>
            <begin position="192"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="243"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="151"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="343"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ40764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="499" mass="56702" checksum="5784700DB928B18A" modified="2010-01-19" version="1">MAKPENNTIVIFGASGDLTHRKLIPAFYHLYANGLLPEDFAILGVSRTAYSDDEFRTKLKKSLIENEKTEQATLEKFCQHLYYQAVNTSDKENYSLLKDRLSVLEDAHHTGGNTVYYLATPPSLYGVIPECLAAHGLNDESNGWKNLIVEKPFGYDLASANALDEQIHACFKEHQIYRIDHYLGKETVQNLLVFRFANGMFEPLWNRNFIDFVEITAAESLGVEDRGGYYDGSGAVRDMFQNHLLQVLAMATMESPAAINADSIRDEVVKVMQSFKPLSDADLNNNLVLGQYTESQVRGKHLPGYRDEHGVADDSRTETYVGLKMFIDNWRWNGVPFYVRTGKRLPTRVTEVVIHFKKTPHPVFGTTAPENKLIIRIQPDEGILMSFGLKKPGAGFEAKEVSMDFHYQDMQESNMLTAYERLLLDCMKGDATLFARTDAVRACWQFVQPILDYKEHPEHLFGYAAGTWGPKEADELLSNDGREWRFPCKNLTNTDYCEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z279</accession>
    <name>D0Z279_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001924</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298950.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40892">
        <property type="protein sequence ID" value="EEZ40892"/>
        <property type="gene ID" value="VDA_001924"/>
    </dbReference>
    <dbReference type="GeneID" id="57341948"/>
    <dbReference type="eggNOG" id="ENOG5031NH7">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2003571at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="67" mass="7665" checksum="E584053F45F87496" modified="2010-01-19" version="1">MNHSQFEVIAKRIFKSENQRVAVAAVIFDGLSSYEAEKRFELPKGTLSRNVRKYKNEVAYIESVVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2A4</accession>
    <name>D0Z2A4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Aspartate aminotransferase</fullName>
            <ecNumber evidence="5">2.6.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_000555</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.1" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304710.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000555"/>
    <dbReference type="EnsemblBacteria" id="EEZ39535">
        <property type="protein sequence ID" value="EEZ39535"/>
        <property type="gene ID" value="VDA_000555"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1448">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="417859at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004069">
        <property type="term" value="F:L-aspartate:2-oxoglutarate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000796">
        <property type="entry name" value="Asp_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11879">
        <property type="entry name" value="PTHR11879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00799">
        <property type="entry name" value="TRANSAMINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="4">
        <location>
            <begin position="27"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="392" mass="42821" checksum="63AC51B567AD1E4C" modified="2010-01-19" version="1">MFKDLAPAQLDPILSLTQAFREDTRDTKIDLGIGVYRNSVGETPIMAAVKLAQERLLESQKTKSYVGLAGYELFNEVMIDLLLSGTQAHSRAAGVQTPGGSGALRMLADLMRVAQPNTTVWLTDPSYVNHKPVMEAAGLKVKFYPYFDRESKQVNSEAMLNALAAAGKDDVVLLHGCCHNPTGADIGFEDWKAVTELAVKNGFTPFVDMAYLGFGDGLVQDGLGLKYMANHVEEMLIAVSCSKNFGLYRERTGAAIVIGATLSDAQKAKGRILTLARSTYTMPPDHGAALVADILTNEDLTRIWQQELISMNHRIIGLRDQLAVAVRNLGSDQFDFIAQHKGMFSVTGLSPIQIQRLRDEYAIYAVGDGRINIAGLQEQHIDYLANALVKVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2A6</accession>
    <name>D0Z2A6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Na(+)/H(+) antiporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_000557</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304716.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000557"/>
    <dbReference type="EnsemblBacteria" id="EEZ39537">
        <property type="protein sequence ID" value="EEZ39537"/>
        <property type="gene ID" value="VDA_000557"/>
    </dbReference>
    <dbReference type="GeneID" id="57342845"/>
    <dbReference type="eggNOG" id="COG0025">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1194802at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015299">
        <property type="term" value="F:solute:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018422">
        <property type="entry name" value="Cation/H_exchanger_CPA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10110">
        <property type="entry name" value="PTHR10110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0050">Antiport</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0915">Sodium</keyword>
    <keyword evidence="7" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="31"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="104"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="133"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="174"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="205"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="296"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="319"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="357"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="391"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="domain" description="Na_H_Exchanger" evidence="9">
        <location>
            <begin position="9"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ39537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="426" mass="46477" checksum="EA7C8A7DBC585C2C" modified="2010-01-19" version="1">MSVYDTICIVAAIAVFISMFNHRFGKFQTTIAITGWSMIIAFSIMLLGKMGVIDFNDEHYLVQLMNNIQFDDFLLKGVLGFLLFGGALNIELSHLKDQKIEISILALAATLFSTFFIGTLLWAILAVIGVNIGYIYCCLFGALISPTDPIAVLAIVKKLKAPQRISTQIEGESLFNDGVGLVIFVTLFEVAFGNHAPTVSGTVALFIHEAVGGIAYGLIIGGIFHYLIKHTHDSMMRLILTMLVPTCGYVIGEQLGVSAPLAMVTAGIIIGNWTRSLISAEESHQLSHLWELADEILNAILFLLIGFVMVTFSFHAVDLVAVIIAIPLVLLSRYISVKLSYVGFGFFRRYNPMSVKILTWGGLRGGLALAMAMAIPTGIPSGFEGVDIKELIVLMTYAVVVFSIIIQGSTITPMIEKAKKYEETGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2B8</accession>
    <name>D0Z2B8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000569</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304735.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000569"/>
    <dbReference type="EnsemblBacteria" id="EEZ39549">
        <property type="protein sequence ID" value="EEZ39549"/>
        <property type="gene ID" value="VDA_000569"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031MPS">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1868259at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="205" mass="24156" checksum="A5660BD65FBF7746" modified="2010-01-19" version="1">MISDILELSIEQFMQDCLQLCEQQYPTIHNRGMREQHIAKALLRRIQSGLQQRGIEAEISQPLELKSLFKITTTDSELWLVAHHFLSANLATRKALIETIDLVVQQPKERVSSYLLIMADHWFDRTKASKELPAWWLDEQPEDWQDYLHSGVRLLPADETLSHQLNQNHYPLLVMDRQLHHPLIHIKHQTHVKRYVVMSGLYQLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2M5</accession>
    <name>D0Z2M5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_000676</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305031.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000676"/>
    <dbReference type="EnsemblBacteria" id="EEZ39656">
        <property type="protein sequence ID" value="EEZ39656"/>
        <property type="gene ID" value="VDA_000676"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0642">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="692375at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004673">
        <property type="term" value="F:protein histidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="161"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="4">
        <location>
            <begin position="240"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="442" mass="49920" checksum="DDC314728BBA9151" modified="2010-01-19" version="1">MPNKRPRRSIRSRLLIAAAVWLSVISLLTGYLVPSFIKTYLIEQEKTQLYLYLDQLTGMIDLTPTGHIKVQGRLSNPRFYSPYSGLYWTLNLDKKQLRSRSLWDTTITGNEKSGYEGPKKQPLIVVERKFLLPESDHPVHLMVAINQDRLVTTIRELTHQVWALLGIMVIGILILITVQISWSLWPLRKLQRNLKEVRAGNINTVTGEYPLEIQPLVDDLNALLFHYQEVLERARNHSGNLSHALKTPIAILNNEVALLEPTQQAKLRPALEQLQQHIDYHLGRARMAGSANILGLKTAPAPRVDAISMAMDKVYAAREVVLVNELDSELMIAVEKRDTDEMLGNLIENSYKWSSSLIRVHKLHDDNGFVTIVIEDDGPGIADNEFSEVLKRGVRLDESTPGTGLGLNIVNELCHSYRGQLKLSRSKLGGLKAELTLPLPRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2N8</accession>
    <name>D0Z2N8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Penicillin-binding protein putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000689</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305062.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000689"/>
    <dbReference type="EnsemblBacteria" id="EEZ39669">
        <property type="protein sequence ID" value="EEZ39669"/>
        <property type="gene ID" value="VDA_000689"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1680">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="537440at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018850" evidence="1">
        <location>
            <begin position="23"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase" evidence="2">
        <location>
            <begin position="41"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="440" mass="49516" checksum="711FCC040C0212FA" modified="2010-01-19" version="1">MKRLIGLCALSLCALTSVNSYATPLDAATNQALSEYLTHQNKYGRFSGNVIIAKKNEILFEQAVGYADVQMQRPIEKNNLFKVGDITKQLTAAAILKLNEQKKLSIDTPISRYFPSLSRSKNITIGMLMNHTAGIGRDFNWSDATQSCSKKNLINPVITSSKTYPPALMFNYSNNGYYLLGRIIEKASGLPYHEYITEQFLRPLGMKDSSMKLTLSFQLAKSYELSGLLNAHITPTGCAWSAGELISTSRDLLVWSRALASGQVINQESLDKMYQHQYGLFAKEIGQTDFYTHSGHIDGFKSILMYEPKSQMTIVALSNFSNTNTELFSVDLVRLLNKQLPIYKVMPPIKHLAPWQDDVDVIGNYMDSLGVPLQVVYQDGELVAKVSQFRIPLMVQNRNTLFAQGIDNKIRIHRNSNETTKEIVFFAKDGRYLSRFARVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z323</accession>
    <name>D0Z323_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">UPF0056 membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_000824</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the UPF0056 (MarC) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000824"/>
    <dbReference type="EnsemblBacteria" id="EEZ39804">
        <property type="protein sequence ID" value="EEZ39804"/>
        <property type="gene ID" value="VDA_000824"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2095">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002771">
        <property type="entry name" value="Multi_antbiot-R_MarC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33508">
        <property type="entry name" value="PTHR33508"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01914">
        <property type="entry name" value="MarC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="49"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="83"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="112"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="153"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ39804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="180" mass="20117" checksum="2C3EB96A7AAB1C96" modified="2010-01-19" version="1">MFSSIIRHIDKKRRRIVLIRELCFALLVMFLFLFVGETVLNFLNLKQQAVSIAGAIILFLIAIRMIFPSKEGSSHMAAGEEPFLVPLAIPMLAGPSILATLILVAHQDPNRMFDWSIALIGAWGASAAILMFSEVFERIVGKKGLTAIERLMGMLLLMLAVQMFLDGVFGYFEYIKTLHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z384</accession>
    <name>D0Z384_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ABC transporter transmembrane region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">VDA_000885</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305629.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000885"/>
    <dbReference type="EnsemblBacteria" id="EEZ39865">
        <property type="protein sequence ID" value="EEZ39865"/>
        <property type="gene ID" value="VDA_000885"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2274">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="643917at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017750">
        <property type="entry name" value="ATPase_T1SS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005074">
        <property type="entry name" value="Peptidase_C39"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03412">
        <property type="entry name" value="Peptidase_C39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03375">
        <property type="entry name" value="type_I_sec_LssB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50990">
        <property type="entry name" value="PEPTIDASE_C39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="157"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="191"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="292"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="379"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase C39" evidence="10">
        <location>
            <begin position="2"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="157"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="469"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="503"/>
            <end position="510"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ39865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="706" mass="78225" checksum="BF338053B120658D" modified="2010-01-19" version="1">MKDPLLQSLVYVSRFYGQANSSDALIADLPLADGLLTPFLLPRAAEKAGLQAKEAKQSITDLSPLLFPVIALLKGGDACVVLSLDKEKNEAEVVLPQADGNEQWISIDDLTAQYTGHLFLIKKRFRYDERSPEILKTRDGHWFWSTLWESKNIYRDVLIASILINIFAIAAPLFSRLVYDKIVPNLAFDSLWVLAIGITIIFSFDLILKLMRSYFIDIAGKKSDILLSAKIFSRVMGIRMEAKPASVGAFARHLQEFESIREFFTSATVSSLIDLPFALLFLLVIYLVGGPIVLVPMVAVVILIIYSFLIQKPLRRSIEEGSRLSSQKHANLIESLVGLETVKMFGAQSQFQYKWEEAVAHMSNWSIKSRKLTDSVQNVAGFLQQFVTVAMIVVGVYLISDGQLTMGGLIASTMLSGRAVGPLVQLSLLSTRYNQAKSAMTIIEQLMEMPLEQEDGKRYIHHPMLKGKIEFDKVSFAYPNSTKAALKNVSFSINPGEKVAIIGRIGSGKTTLERLIMGLYRPTEGSVRIDNTDINQMHHIDIRRNIGCVPQDITLFFGSIRDNITLGRPLATDKDILIAAERAGVTSFTQHDDAGLEKQVGEGGLALSGGQRQSIAIARALLSKPPVLVMDEPTSSMDNRSEMYIKHQLASLSNEETLILITHKTSMLDIVDRLIVMEQGQIIADGKKDLVLQQLREGAVNKAKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3J5</accession>
    <name>D0Z3J5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Pyridoxal kinase</fullName>
            <ecNumber evidence="1">2.7.1.35</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000996</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.1.35" evidence="1"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000996"/>
    <dbReference type="EnsemblBacteria" id="EEZ39976">
        <property type="protein sequence ID" value="EEZ39976"/>
        <property type="gene ID" value="VDA_000996"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2240">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008478">
        <property type="term" value="F:pyridoxal kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009443">
        <property type="term" value="P:pyridoxal 5'-phosphate salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013749">
        <property type="entry name" value="PM/HMP-P_kinase-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004625">
        <property type="entry name" value="PyrdxlKinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10534">
        <property type="entry name" value="PTHR10534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08543">
        <property type="entry name" value="Phos_pyr_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00687">
        <property type="entry name" value="pyridox_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phos_pyr_kin" evidence="2">
        <location>
            <begin position="9"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="170" mass="18414" checksum="7B5C985BA2449B1C" modified="2010-01-19" version="1">MGAPDKGCIVAPGIAEHLINDVMPMADVIVPNQFELSQFVGMEINNLEDAVAACKAALTKGPKVVLVKHLHSVSDEQFTMMLATEKGCFIAQRPHLPFDLQPVGVGDLISSLFTGGLLKGWTPEQAFEHAHNACYGVLKETHKRGEWELQTIAAQEELVAPTEIFPAQAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3L8</accession>
    <name>D0Z3L8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glyco_trans_4-like_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001019</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305998.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001019"/>
    <dbReference type="EnsemblBacteria" id="EEZ39999">
        <property type="protein sequence ID" value="EEZ39999"/>
        <property type="gene ID" value="VDA_001019"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1591999at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="1">
        <location>
            <begin position="20"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="423" mass="49166" checksum="CC36645D183B7AD6" modified="2010-01-19" version="1">MKILYISYFSPPLLNVGAHRTRRFASHLTTFNHKVTVIAEKRRNRFTQQSKDALSAPNTLLIDAVKSWNIDWLWKYPTIVHKGLYRLFGRTLPEQDNKIAKRYWFIDMQWGWIIPTLWHCYHLIKQDKPDVILVTCPPFSSSVVGYYLSKFFSIPLVLDFRDGWTHASYFVEYDYQHWESRVLAQASALVVTSKADLHSYQSKYPKVAVSYIPNSFDWPLDITSNRSSSCCDSKRVFTIGYSGTWDGFRRSAKQILTHLSQASFDFRFINIGDDHPEFLSLVDELKIEDKVRNLGLLNKDKMLKYLADCDALFIQKGLPDLDLEDTHLATKAIDYVASRRMIIAELPKGETKQFLLQYGGKVVMVDADNYSQQLESAYQYWCSNPNKRYEPKGDFWQHYDPILLSRQLEKVCYDVCSGSSQAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3T8</accession>
    <name>D0Z3T8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH cro/C1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001089</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306195.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40069">
        <property type="protein sequence ID" value="EEZ40069"/>
        <property type="gene ID" value="VDA_001089"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1933795at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="6"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="258" mass="30984" checksum="C8024980A598A2B3" modified="2010-01-19" version="1">MFNHFLSQYREENNLTQQDMVDQLASYHPSFNKLDTVTLSRWENEKTLPPLKKQFLVFDYINKLCEFTTAYIPSIKDQYPLLESYINNKFENSNIIISDILNTNNCYFTKTNNDPYLNIEQFVIDYFQNEFVSDFVLRENIETISWNKNNQLEACLIYTSPIKEHNNDNMIFMGVFAKNRTSFELIYRELYELILESNVENIIMYSFDDNGYKLFKKLGGEIIKITRISKDIIKYIFKFNRIDFLSNKDIFFYYKSLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3V3</accession>
    <name>D0Z3V3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">ATP synthase subunit c</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">ATP synthase F(0) sector subunit c</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">F-type ATPase subunit c</fullName>
            <shortName evidence="13">F-ATPase subunit c</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Lipid-binding protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">atpE</name>
        <name evidence="15" type="ORF">VDA_001106</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 13">F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.</text>
    </comment>
    <comment type="function">
        <text evidence="13">Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cell membrane</location>
            <topology evidence="13">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the ATPase C chain family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306237.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001106"/>
    <dbReference type="EnsemblBacteria" id="EEZ40084">
        <property type="protein sequence ID" value="EEZ40084"/>
        <property type="gene ID" value="VDA_001106"/>
    </dbReference>
    <dbReference type="GeneID" id="57343433"/>
    <dbReference type="eggNOG" id="ENOG5032S3K">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2078221at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045263">
        <property type="term" value="C:proton-transporting ATP synthase complex, coupling factor F(o)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01396">
        <property type="entry name" value="ATP_synth_c_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005953">
        <property type="entry name" value="ATP_synth_csu_bac/chlpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000454">
        <property type="entry name" value="ATP_synth_F0_csu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020537">
        <property type="entry name" value="ATP_synth_F0_csu_DDCD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038662">
        <property type="entry name" value="ATP_synth_F0_csu_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002379">
        <property type="entry name" value="ATPase_proteolipid_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035921">
        <property type="entry name" value="F/V-ATP_Csub_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10031">
        <property type="entry name" value="PTHR10031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00137">
        <property type="entry name" value="ATP-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00124">
        <property type="entry name" value="ATPASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81333">
        <property type="entry name" value="SSF81333"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01260">
        <property type="entry name" value="ATP_synt_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00605">
        <property type="entry name" value="ATPASE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 13" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="13" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 13" id="KW-0138">CF(0)</keyword>
    <keyword evidence="6 13" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 13" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 13" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 13" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="6"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="52"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-synt_C" evidence="14">
        <location>
            <begin position="11"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="site" description="Reversibly protonated during proton transport" evidence="13">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEZ40084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="78" mass="7940" checksum="869544D461650708" modified="2010-01-19" version="1">MDIVSAVLYVAGALLIGLGAAGAATGIGNLAGKYLEGVARQPDLTPMLRTQFFIMMGLVDAVPMIGVGIGLYIIFAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-02-10" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3W9</accession>
    <name>D0Z3W9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">PTS system N-acetylgalactosamine-specific IID component</fullName>
            <ecNumber evidence="10">2.7.1.69</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_001122</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.7.1.69" evidence="10"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306276.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001122"/>
    <dbReference type="EnsemblBacteria" id="EEZ40100">
        <property type="protein sequence ID" value="EEZ40100"/>
        <property type="gene ID" value="VDA_001122"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3716">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1632067at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103111">
        <property type="term" value="F:D-glucosamine PTS permease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008982">
        <property type="term" value="F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004704">
        <property type="entry name" value="PTS_IID_man"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03613">
        <property type="entry name" value="EIID-AGA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51108">
        <property type="entry name" value="PTS_EIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0598">Phosphotransferase system</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="94"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="134"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="161"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="251"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="275"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ40100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="294" mass="32060" checksum="B03E3D1524300ACC" modified="2010-01-19" version="1">MESNITHDMKLNQYNSEVQPAPGIAADEYENKEIGAELTKADINRMAWRSLLLQASFNYERMQASGWLYGLLPALKKIHTNKADLSKAMQGHMGFFNTHPFLVTFVMGIILAMERSKQNINSIQSTKIAVGAPMGGIGDAMFWLTLLPICGGIGADLALQGSIMGAVFFFVLFNIVHFGLRFGLAHYAYRMGVSAIPMIKANTKKVGHAASIVGMTVIGALVATYVRLSTTAEITAGDAVVKLQADVIDKLMPAFLPLTYTLCMYALVKRGWSPLKLIAITMTLGIVGRFMGFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z461</accession>
    <name>D0Z461_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000317</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304026.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000317"/>
    <dbReference type="EnsemblBacteria" id="EEZ39299">
        <property type="protein sequence ID" value="EEZ39299"/>
        <property type="gene ID" value="VDA_000317"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1661500at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="300" mass="33502" checksum="5768926C1655162B" modified="2010-01-19" version="1">MRTSDDLILFYHLIEHGSFSKAAEQAGITKSVISKRISKLEADLGVQLIYRTTRKLTPTEAGIIFYSHARDVYHSVQNAMNAMSGLGESISGTIKITVPTISGEMILPQAISEFSQQYPDIKIEMDLDNRFVDIIDKGFDLAIRTRALPDSSLIARKLINAHWIICVSPAYLRKYGLPQHTSELTSHNCLGYSYQETGASEWLINDNQGIHTMTVKGNFTTNNASALRQAALLGQGIIYVPKILVSADLANGDLQEIFSGQAAKHLGIYAVYPYTKQQAIKIKLFIEHLHKCYQQHKNLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z468</accession>
    <name>D0Z468_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Hypothetical amidinotransferase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_000324</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the amidinotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304047.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000324"/>
    <dbReference type="EnsemblBacteria" id="EEZ39306">
        <property type="protein sequence ID" value="EEZ39306"/>
        <property type="gene ID" value="VDA_000324"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1834">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="592329at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015067">
        <property type="term" value="F:amidinotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033195">
        <property type="entry name" value="AmidinoTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10488">
        <property type="entry name" value="PTHR10488"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="224"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="274"/>
        </location>
    </feature>
    <feature type="active site" description="Amidino-cysteine intermediate" evidence="3">
        <location>
            <position position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR633195-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="410" mass="46783" checksum="6576416260B4ADF7" modified="2010-01-19" version="1">MSISNDLYPNASLPLERKDSGVPIVRPGLHVESYNDFDPLRHVIVGIADNQHIPEACPASNEKIPADSPMRGSKAGRRTQETIERANECLNGFAKILENRGIIVDRPGAVDWHSRITTPDFSISSGFGCMPPRDCLLTMGKSILMAPMSFRSRYFEYLAYVDLLREYFESDPECMIEQAPRPRLSDDSFRMDYVAAYEYLSDEETMARSLRKEYSTKETDILFDAADVMRLGKDIFVQHGLTTNLAGIRWIKRKYEPMGYRIHTLSFEDNHPIHIDATFCPLRPGLMLLNPHRPLFKGQRDIFEKNGWEIVEAVQPAWDNPPPLCYSSTWLSMNTLILDHKTVCVEASEHGQMEQFDKLGFEVVPVDLRDAYAFGGGLHCATADVWREGTCEDYFSNQFFGAHSVENWEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z488</accession>
    <name>D0Z488_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NAD(P)-bd_dom domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000344</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304103.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000344"/>
    <dbReference type="EnsemblBacteria" id="EEZ39326">
        <property type="protein sequence ID" value="EEZ39326"/>
        <property type="gene ID" value="VDA_000344"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0702">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="948454at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="1">
        <location>
            <begin position="8"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="211" mass="23276" checksum="AD1E8D560EF0DD15" modified="2010-01-19" version="1">MENVAIFGASHGLGLAMAKYYSQQGFSVIGLGRGDKPSPEFSLLSGQWIQCDALDLMQVQTAVQMLPNSCWVISTMGSFNAEQYVDYQGNRHIIDCLEERGGLRFLLITSLGCGDSWQYLPPRAKAVFGRAVREKSLAEMWLQTSALDYTIVRPGGLIDGELTHTGELSQGQEVHGCISRTEVARLSHQLLMDSLSIGQIYHCVDPNAKYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4E1</accession>
    <name>D0Z4E1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000397</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304253.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39379">
        <property type="protein sequence ID" value="EEZ39379"/>
        <property type="gene ID" value="VDA_000397"/>
    </dbReference>
    <dbReference type="GeneID" id="57343214"/>
    <dbReference type="eggNOG" id="ENOG5031N4F">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1823752at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="116" mass="13603" checksum="FB2F60EC22EF6457" modified="2010-01-19" version="1">MQQNEFEVLVKELAQKETITDVLNALSAVEEEEIAQAAEDLKGHFCLAEIEGEKRIYHVFTQENEAGEEQEFVEWVMNEGEEMLKFAAWFFYTNFEIKQRDTYQAAGRTYQQPKRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4I8</accession>
    <name>D0Z4I8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000446</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304389.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000446"/>
    <dbReference type="EnsemblBacteria" id="EEZ39426">
        <property type="protein sequence ID" value="EEZ39426"/>
        <property type="gene ID" value="VDA_000446"/>
    </dbReference>
    <dbReference type="GeneID" id="57342611"/>
    <dbReference type="eggNOG" id="ENOG5032ZCT">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1926133at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021343">
        <property type="entry name" value="DUF2960"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11173">
        <property type="entry name" value="DUF2960"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="87" mass="10002" checksum="9168DA35AD2BC3CA" modified="2010-01-19" version="1">MARTVVYTYKNEEKQISFTYDQFRNIHEAVAAAEGIDLTSYLKMELQVEMVSSSAKAVRDFRDSHFRKLGFGKIAFLPKENRGVGHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4K5</accession>
    <name>D0Z4K5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="12">L-asparaginase</fullName>
            <ecNumber evidence="12">3.5.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">VDA_000463</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the asparaginase 1 family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.1" evidence="12"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304433.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000463"/>
    <dbReference type="EnsemblBacteria" id="EEZ39443">
        <property type="protein sequence ID" value="EEZ39443"/>
        <property type="gene ID" value="VDA_000463"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0252">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1659551at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110165">
        <property type="term" value="C:cellular anatomical entity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004067">
        <property type="term" value="F:asparaginase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006528">
        <property type="term" value="P:asparagine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08964">
        <property type="entry name" value="L-asparaginase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004550">
        <property type="entry name" value="AsnASE_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036152">
        <property type="entry name" value="Asp/glu_Ase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006034">
        <property type="entry name" value="Asparaginase/glutaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020827">
        <property type="entry name" value="Asparaginase/glutaminase_AS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027475">
        <property type="entry name" value="Asparaginase/glutaminase_AS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040919">
        <property type="entry name" value="Asparaginase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027473">
        <property type="entry name" value="L-asparaginase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027474">
        <property type="entry name" value="L-asparaginase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037152">
        <property type="entry name" value="L-asparaginase_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00710">
        <property type="entry name" value="Asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17763">
        <property type="entry name" value="Asparaginase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001220">
        <property type="entry name" value="L-ASNase_gatD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00139">
        <property type="entry name" value="ASNGLNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00870">
        <property type="entry name" value="Asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53774">
        <property type="entry name" value="SSF53774"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00520">
        <property type="entry name" value="asnASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00144">
        <property type="entry name" value="ASN_GLN_ASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00917">
        <property type="entry name" value="ASN_GLN_ASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51732">
        <property type="entry name" value="ASN_GLN_ASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018848" evidence="9">
        <location>
            <begin position="24"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="Asparaginase" evidence="10">
        <location>
            <begin position="29"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="Asparaginase_C" evidence="11">
        <location>
            <begin position="241"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="117"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="38"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="5">
        <location>
            <position position="38"/>
        </location>
    </feature>
    <feature type="active site" description="O-isoaspartyl threonine intermediate" evidence="3">
        <location>
            <position position="38"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="117"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001220-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR001220-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR604550-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF17763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ39443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="354" mass="37978" checksum="CBA5B0EF0BF323B2" modified="2010-01-19" version="1">MKKNPIRLGMLAAGLCFSSFSFAATDLPNIKILATGGTIAGAGQSATKSNYTAGKVGVDALIAAVPDMTKIADISGEQVVSIGSQDMNDEVWLKLAKRVNELLAQDDVDGIVITHGTDTMEETAYFLDLTVKSKKPVVLVGAMRPSTAMSADGPVNLYNAVVAATDEDSKGRGVLVTMNDTIFDARDVTKTNTTSVNTFQSPNFGPLGYVHNSDAKYQRSPERKHTTETVFDVSKLTSLPKVGIVYNYANASDLPVKALIDAKFDGIVSAGVGNGNLYHTVFDQLEKASKDGIMVVRSSRTPTGSTTLDAEIDDAKYGFVASGTLNPQKARILLMLSLTQTKDYKDVQKMFQYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z501</accession>
    <name>D0Z501_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000234</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39218">
        <property type="protein sequence ID" value="EEZ39218"/>
        <property type="gene ID" value="VDA_000234"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="107" mass="12675" checksum="22439F47729FB6B2" modified="2010-01-19" version="1">MIDRLVLHIPTEKNFRAIRYYGFLSNRKRGEALPLVYDLLDQEELVEPKPLNYAQMMHHLVGIDPYKCILCGGRMCFVKMDMGLKGHELVALRKATIREKRRLRYRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z535</accession>
    <name>D0Z535_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">IncF plasmid conjugative transfer pilus assembly protein TraH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000270</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306782.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000270"/>
    <dbReference type="EnsemblBacteria" id="EEZ39252">
        <property type="protein sequence ID" value="EEZ39252"/>
        <property type="gene ID" value="VDA_000270"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502ZB1J">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1819710at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010927">
        <property type="entry name" value="T4SS_TraH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06122">
        <property type="entry name" value="TraH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003020094" evidence="1">
        <location>
            <begin position="20"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="456" mass="49773" checksum="4B10619C2D4EF4C6" modified="2010-01-19" version="1">MNKIVALAVLMAFSASSFAGTTGDLGGFFDGLNYQGNITAPQSYKGQMASYYSGGGAYIRTPVKQAQMAAFTVPEIKAGCGGIDLFSGGFSFINSDQLVQMGKAIVSNAIPFAVDLALQTWAPQLKQIKDRLEAIAREINALSVNSCETAQAGVAALAGFAGVGNKQYICSTMGTQNNKFADWAAAKNGCNNESAVNDGIKQASKDRNLKEHIPVNRNIIWYSLKKYSTIRDDNTSEFFMSLSGTIVYNEKGDVIRYPSLLTTSNDLINLLTLGGKAQVYRCNNYGENQCLKPKIQDMSFSQHDTLKFKVSKILRSIIEKYKKDQGLSDSEKQFLESISLPVLKMMTVSLESGYSLDATVNDYATVISTDLVTAYLQDALRLIKTAIDSKGSAPEDVDKLYAVITQASEQMRLIRVQALQSLEAEQSIIQATMQLEQRVEGQFSAQTRASLLFSKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z543</accession>
    <name>D0Z543_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chromosome (Plasmid) partitioning protein ParB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000093</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306824.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000093"/>
    <dbReference type="EnsemblBacteria" id="EEZ39077">
        <property type="protein sequence ID" value="EEZ39077"/>
        <property type="gene ID" value="VDA_000093"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1475">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="467563at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014884">
        <property type="entry name" value="ParB_fam_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08775">
        <property type="entry name" value="ParB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ParB" evidence="1">
        <location>
            <begin position="196"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="319" mass="36552" checksum="45502FDE3883A584" modified="2010-01-19" version="1">MFRPQDKRVGFKQGNQLTKRNIQESEQKVFIFASGAKVTASRIVVPSHDIQEKTSIHELNPRCQASLSLDSVRDILPSIEAEGVYTEGVAIKDSDGMYQLIDSSRRRYCCLTVCKDLPLWVIDGDVSRDDLLSFIDTTQSVKRLSYRELGMNYQSIMVDNALTKLEELADYLSIGRETCRKRLVAASIDQKLINVFPDCEGIPNTFYAKLAKIEKSLIKDNQDIDQFIESVISDFVADNLPVEDKQKLILKEMEEKLPNKKTKNTWTTKVLADFEDKNTYAKVMYSNDKRGLKIELNRLPSNLYQDIVDYIENKIKNEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z598</accession>
    <name>D0Z598_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Rhs family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_000148</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306984.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000148"/>
    <dbReference type="EnsemblBacteria" id="EEZ39132">
        <property type="protein sequence ID" value="EEZ39132"/>
        <property type="gene ID" value="VDA_000148"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3209">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1639867at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029476">
        <property type="entry name" value="DNase_NucA_NucB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022385">
        <property type="entry name" value="Rhs_assc_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003284">
        <property type="entry name" value="Sal_SpvB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14040">
        <property type="entry name" value="DNase_NucA_NucB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03534">
        <property type="entry name" value="SpvB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="SSF69318"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03696">
        <property type="entry name" value="Rhs_assc_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003020047" evidence="5">
        <location>
            <begin position="22"/>
            <end position="2301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="2073"/>
            <end position="2093"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="2242"/>
            <end position="2267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="2073"/>
            <end position="2088"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="2242"/>
            <end position="2256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ39132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="2301" mass="260509" checksum="CA8CA2811C4A71DA" modified="2010-01-19" version="1">MKKVIHGLLFSLTLFSVQSNADSPYLDGEFTVSGGQANYNVSLELPKGRAGYTPSLAIAYNSNGVNNELGLGWQIEGKSTIARCARTLSTDGQWGGVKFDDNDRYCVNGKRLIAITGKDGAHLTEYRTEVDDGNKYVSFNKVGSGPEYFKAWTPDGEEHTYGGTADSKLVLAGNVLSWDISQDRDNSNNLINYTYLTDNNIKYLSAVNYVGGKVHFNYVDRKDYVTKYFLGYKQIRKKRLNDITISNNYNQVVNKYTLSYKYADTSGLSLITAISKSISGYEITPIKIHWSYMPSSTGPSVNHILNVANPILYDKERDGVFETVSHSNHQTLGIWRNEGLTTLKNCDSSTGCYAADNNGDGINNLSKSRLYDMNGDGKTDGSGYGNVLDINNDGLMDSYTYLSGHENWTGCGKHECQKWLNYSSLNVNLQNSQLNLLYYCSTSGGNCRYSDYLYHSSKFKDVAFYDMNNDGYKDILFKLYDSPNYRIMINNGNRFEAPVELSNTANLISQVLDINHDGINELILKDRHGRDHQIVYLTPEINKVKTVKHYNGNAYYADVNSDGIYEKITVNDNKYTSIVRFTPNVFHVDAIETYADKIDISYAPISNKNVHKQKVHFDFPVINTTPFLIVVNRIKNKTGTTRYEYVGAKSHVNGGGFLGFESITSRHYSNDGIATEVYSKYEQYRDVGGKVKKLPTGNLIYQTKKINNKILSEEWAHYTHKVQTGYDGKYSYQIRRTENTAKYQDDMGYNLGLIQKTYAYNDVGRVVKTVTSKSLSGQPTFTQVDETSYLSSGLPTYKVINQAQNSASSHIAKNLAHYDHLDVWCGSDGQQYIKPRNKFILIHGEIVTPILVGDFPYFYRLNVKSHSSNATSNTQIKNTSFTAVSQSEFTSKSPQLCGEYYVYDYNGDGLQDLVSQKGSLTTLVSESGKEFWKTNAIKQRTTTVTFNGLTQQSMGSMSYDTRGRLLAQRTQSSDYGTTSMGAKSLIQQFEYDDYGNVISETTGGTNTASRTDRTTYDSYGIFPVSTSNALGHTTTYEYDQLFGLVTMVTDPNNRVTRNAYDVYGRLQQTWLPGSNNWVKYSYRLGNNCEAKANQAISCILTEKNGRGKTITQFDRLGREVRNINQSFDGRWVYEDQSWDSLGQKLRHSRPSFEKPDPSMSNVPHSQFRYDSLGREVYSKVPSDSGNGWHESQIVYQGLKETYTESKVGGIYTKTITKNLLGQIIKVDEPLGASQTYTYYPDGKLKTTTDSANNTTTVQYDNLGYRKLLIDPDLGTLHYDHNVFGELVYKRDANDKTTRITYDQLGRKTYENISGIVSTWEYDRRGKGLLYRQQSPGNTKELFYNNGLLVEEKMVAKGQTLIQRYKYDSFERIAEEIRPNDLVLQYIYNEFGYHSAVRSPKSAADSIFTSLSFQQDVRALINAAASQAQKYLNLADRYAQQRDFYQRKANEIKGNSVDIYELDVQSLNLLHGAQRFRKYCNNAGACYLQPATWLILHDEVSIPLDVTLDQYYRLTQRYSRTQDGNRYFDTTVYAASSDELNNSGATQQEDWVLKDHDNNGSLDLIAGKHLYGAYKDASTKQEINFTAQELTLASEIANTRYQTYRQLVAKLVVLSQQVAKLSGLYKQDEQNTNKQKAHLQTIVHQSELAKADKNAFIYYWQRTNTDAYDHTTSEVLGNGLANSYVHSEKTGRARIIATHKASHVVSQLQLSNHQFIKNGYRQIYYNYDNWGNVTQRYDRSLGLNERFTYDLLDRVTSATPMLDDQNQHGAGNPDFNRRFEYHYDRLGNITYKTGIGHYEYRSSHKHAVTQAGDTHYDYDAAGNMVRATKQDKEERSIVWTSFNKPERITRNGHITSFEYDANHARFYREDSNGKQILYLGKTYEQILDTKTKHVEYKQYIYADGKLIALHVSEYDNQRNLKDKQIRYLHYDALSSVDLITDGYGNIVERRSFDSWGKARKLLWQDPHDPATLVQLNLTTRGFTGHEHLEEVGLIHMNGRVYDADIGRFISPDPVVQAPFMTNSFNRYSYVMNNPLKYTDPSGYYTATETDNITGQTTEVNLGRDVHETVTITADRNDNGSYGSHNTQSDRRENQITETSKQTYYVYGANKHFYEQSSLESRARITETLVGLGLDMSPLGLGRDFYEFYDELVNPLDSNPNSASLSVITGGIYQLAGLFIAKKAKSFDKLQEIGNVTKRVEVSLSRHPEAAKHIQDAQAAGHPKTLTIDRANALANRKASLKGVPTKKGLDRDEYPPAMFKEGGSGASVRHINPRDNRGAGSCIGGQCSGLPDGTRVRINVVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5A5</accession>
    <name>D0Z5A5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC-type antimicrobial peptide transport system permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_000155</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005307002.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000155"/>
    <dbReference type="EnsemblBacteria" id="EEZ39139">
        <property type="protein sequence ID" value="EEZ39139"/>
        <property type="gene ID" value="VDA_000155"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0577">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="768211at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="286"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="350"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="390"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="9">
        <location>
            <begin position="21"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="8">
        <location>
            <begin position="322"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ39139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="427" mass="46557" checksum="0F0411115CB18A2A" modified="2010-01-19" version="1">MLLPMRQIFQEMAAEKLRLGLTILAVTWATMCIAAMLSVGEGIRQGVLRTAQNGNGNLIYLTGGMATIDYGSFHQGKFLTLKVDDADVIKALPEVKSVASTAIWNERMTVGDRGSWQDPLAVIPDFASMTNLTTMDGGRWLNPLDQKQARKVVVLGYSLAADLFNPVDNFNWFAPVTLQTDPVGKKVKIGSEEFTVIGVLKKSSAEIEQDDQINYSSFVPLATWQRFHVNGDISGINVEPQANTDRKKLAESIRQVITRKHGASVSDEQVVQVEDMFLRQKSMQQFLIGLQSFLGIIGFVTLAVAGIGIANVMYATVKRSTRDIGVRMAVGATPTAIRLHYLVQSLMTMMLGGILGLGVTYALVSLISAINLEGNIFYEYLGKPVPELSWVVVAIVIIALVIIGVISAWLPANRAAKVSPLEALQSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5H5</accession>
    <name>D0Z5H5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000082</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000006">
        <property type="protein sequence ID" value="EEZ39027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005307180.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000006.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000082"/>
    <dbReference type="EnsemblBacteria" id="EEZ39027">
        <property type="protein sequence ID" value="EEZ39027"/>
        <property type="gene ID" value="VDA_000082"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3266">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2124561at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003020057" evidence="2">
        <location>
            <begin position="25"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="310" mass="34205" checksum="E1E7C57878327C67" modified="2010-01-19" version="1">MKLTYIHTAIVGVMSLALHPSYLAAQPIAQLISNDGHEQIVIQNIPKPPPFIAPTRNEVKAENIYQERKPLPVITEKTPVKHIAQHLPKQGREKPKGIQNLPSQAKSLPPIRADLAAKAKSKPPLLKKLPPQSINASAEPSFYVSQGQTYMTAIRNWLTQNKLSRVAWSLPPATVAALNTPSSNGNLFKGDIESVIKQVGDKVGKPLYFSRNAKGMAAIHNIKGSVDILWINGATIKDAVKNLTLQYHWQWKNGDNSSWMAPDNYTLIAPYPVVAPRGDFAYALNTVLDGYPVQAQLLYATKNIFVVEKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVH5</accession>
    <name>D0YVH5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative cytoplasmic protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001555</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298270.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001555"/>
    <dbReference type="EnsemblBacteria" id="EEZ40529">
        <property type="protein sequence ID" value="EEZ40529"/>
        <property type="gene ID" value="VDA_001555"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3615">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1905128at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015392">
        <property type="entry name" value="DUF1971"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014510">
        <property type="entry name" value="Tellurite-R_YeaR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09313">
        <property type="entry name" value="DUF1971"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF020632">
        <property type="entry name" value="YeaR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1971" evidence="1">
        <location>
            <begin position="14"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="112" mass="12737" checksum="D654E843E305AAF2" modified="2010-01-19" version="1">MSHLRIPADWTVQRSTPFFTKDNVPAALLTHHNTAEGVFGQLCVMEGQVTYYGFADADATEPEVKVVINAGQFATSPPQYWHRIEMSDDAQFNINFWSNKDKRNQPMFSAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVI9</accession>
    <name>D0YVI9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DNA-binding protein inhibitor Id-2-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001569</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298298.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001569"/>
    <dbReference type="EnsemblBacteria" id="EEZ40543">
        <property type="protein sequence ID" value="EEZ40543"/>
        <property type="gene ID" value="VDA_001569"/>
    </dbReference>
    <dbReference type="GeneID" id="57342373"/>
    <dbReference type="eggNOG" id="ENOG50330CB">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1973284at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013468">
        <property type="entry name" value="CHP02647"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18918">
        <property type="entry name" value="DUF5669"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02647">
        <property type="entry name" value="DNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="81" mass="8869" checksum="D2078D9B94BE348A" modified="2010-01-19" version="1">MPYTADIVNEMNLLVKFPMHSNLEGIKVHSNATPEMVEAAKRLYAKGLVTQEDGGYLTYAGHQAVEHAKAALRILTGKVSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVK9</accession>
    <name>D0YVK9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acetylornithine deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001601</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298357.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001601"/>
    <dbReference type="EnsemblBacteria" id="EEZ40574">
        <property type="protein sequence ID" value="EEZ40574"/>
        <property type="gene ID" value="VDA_001601"/>
    </dbReference>
    <dbReference type="GeneID" id="57342322"/>
    <dbReference type="eggNOG" id="COG0624">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1015417at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017150">
        <property type="entry name" value="Pept_M20_glutamate_carboxypep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037238">
        <property type="entry name" value="Carboxypeptidase_G2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="3">
        <location>
            <begin position="174"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="78"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR037238-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="374" mass="40113" checksum="E30F813109B3F668" modified="2010-01-19" version="1">MSFSLEQYLEELRPLINVDCGTLTKEGIEVIANQMAEKYQTLGWNVKRVDCGAAGTGLEVRNKPEADHIDVMLIGHMDTVFPVGTAAARPMTTDAEKAYGPGVSDMKSGLLNIVYAIRTLDPTVLEKLSICVCMNPDEEIGSLHSETWLKSVAASAKHVLVAEAARADGSLVKARKGMARYRLTFNGKAAHAGNEPEKGRSAITEMANWILAINQLTNFETGTTFNVGIVKGGAGANIVPDLAEAVVDVRFWDNEEYAQADSHIRALADTPFVDGVSITLDREAHKPSMVPSTQTEALMTLVEQSGQEEGINITWQAVGGGSDANLTAVLGIPTLDGLGPIGAGFHSADEYLVLDSIEPRIRLLQNVLGKIAKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVL7</accession>
    <name>D0YVL7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Asparaginase</fullName>
            <ecNumber evidence="1">3.5.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_001585</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.5.1.1" evidence="1"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001585"/>
    <dbReference type="EnsemblBacteria" id="EEZ40559">
        <property type="protein sequence ID" value="EEZ40559"/>
        <property type="gene ID" value="VDA_001585"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0252">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004067">
        <property type="term" value="F:asparaginase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08963">
        <property type="entry name" value="L-asparaginase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006033">
        <property type="entry name" value="AsnA_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036152">
        <property type="entry name" value="Asp/glu_Ase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006034">
        <property type="entry name" value="Asparaginase/glutaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027475">
        <property type="entry name" value="Asparaginase/glutaminase_AS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040919">
        <property type="entry name" value="Asparaginase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027473">
        <property type="entry name" value="L-asparaginase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041725">
        <property type="entry name" value="L-asparaginase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027474">
        <property type="entry name" value="L-asparaginase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037152">
        <property type="entry name" value="L-asparaginase_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00710">
        <property type="entry name" value="Asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17763">
        <property type="entry name" value="Asparaginase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001220">
        <property type="entry name" value="L-ASNase_gatD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00139">
        <property type="entry name" value="ASNGLNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00870">
        <property type="entry name" value="Asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53774">
        <property type="entry name" value="SSF53774"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00519">
        <property type="entry name" value="asnASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00917">
        <property type="entry name" value="ASN_GLN_ASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51732">
        <property type="entry name" value="ASN_GLN_ASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Asparaginase" evidence="4">
        <location>
            <begin position="14"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="Asparaginase_C" evidence="5">
        <location>
            <begin position="198"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="75"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="75"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR001220-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="321" mass="35112" checksum="4BF5B0E9762F15F7" modified="2010-01-19" version="1">MQKSDHGYIPVAGFMEKQLASMPEFHRAEMPEFTIHEYAPLIDSSDMTPSDWQRIADDIKANYDKYDGFVILHGTDTMAYTASALSFMFENLDKPVIVTGSQIPLAELRSDGQSNLLNALHIAANYPINEVTVFFNNKLIRGNRSTKAHADGFGAFISPNLPPLLEAGINISVSNIAEINKKPEGPFKVHNIIPQPIGVITMYPGISPEVIKNTLRQPVNAMILLTFGVGNAPQNPELLEQLKEASDRGVIVMNLTQCLSGKVNMGGYATGCALADAGVLSGYDMTPEAALAKLHFLLSQDLPVESMRTLMQQDLRGELTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVU6</accession>
    <name>D0YVU6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">Thiopurine S-methyltransferase</fullName>
            <ecNumber evidence="4 9">2.1.1.67</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Thiopurine methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">tpm</name>
        <name evidence="10" type="ORF">VDA_002027</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>S-adenosyl-L-methionine + a thiopurine = S-adenosyl-L-homocysteine + a thiopurine S-methylether.</text>
            <dbReference type="EC" id="2.1.1.67"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.67" evidence="4 9"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002027"/>
    <dbReference type="EnsemblBacteria" id="EEZ40995">
        <property type="protein sequence ID" value="EEZ40995"/>
        <property type="gene ID" value="VDA_002027"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0500">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008119">
        <property type="term" value="F:thiopurine S-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010038">
        <property type="term" value="P:response to metal ion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00812">
        <property type="entry name" value="Thiopur_methtran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022474">
        <property type="entry name" value="Thiopur_S-MeTfrase_Se/Te_detox"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025835">
        <property type="entry name" value="Thiopurine_S-MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008854">
        <property type="entry name" value="TPMT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05724">
        <property type="entry name" value="TPMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF023956">
        <property type="entry name" value="Thiopurine_S-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03840">
        <property type="entry name" value="TMPT_Se_Te"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51585">
        <property type="entry name" value="SAM_MT_TPMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="7 9 10" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="9">
        <location>
            <position position="24"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ40995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="226" mass="26033" checksum="232D46D06477FFEC" modified="2010-01-19" version="1">MQKRITTKKRVVSNMNPEFWHSRWAENRIGFHLTDINPLLVEYWPTLKPQRNERVLVPMCGKSNDLVWLAERHNQVVGIELSDIAVKAFFAENLYTPLVTGVGHQLTYEFDEITIHCGDFFATQIEPVELVYDRAALVAMPQELRQAYVNHLLSLTAENGRILLVSLDYPQAEMAGPPFSVDQQEIEQLFSGCKVSRLARDEGDENHPRIKQGVSRFAEEVWLIER</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVU8</accession>
    <name>D0YVU8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002029</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002029"/>
    <dbReference type="EnsemblBacteria" id="EEZ40997">
        <property type="protein sequence ID" value="EEZ40997"/>
        <property type="gene ID" value="VDA_002029"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0697">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="140"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="171"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="257"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="1"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="140"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="277" mass="30419" checksum="B7753A5B375AF137" modified="2010-01-19" version="1">MLTAGLAFAIVNSLAQYLSIKLGLPSTTVALIQYFIALIAMLPWLHSLGLRQALRTQHFATHCFRVFLSVIGIQLWLWALAYPVPIWQGIALLMTSPLFATIGSGLFLKEKVGAARWIATIAGFIGAMIILEPWSDSFNWATLLPVGAAFFWACYSLMVKKQSKHDSPTTIVVYLLILITPFNIFLAAPDFTMPSSGLTWALLVAAGLLTGLAQWAIAKAYAVADASFVQPFDHAKLPLNVLAGWLVFGWVPPGRLWLGAAIIIFSVAFITQWEKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVZ9</accession>
    <name>D0YVZ9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glutamate--cysteine ligase</fullName>
            <ecNumber evidence="5">6.3.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Gamma-ECS</fullName>
            <shortName evidence="5">GCS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Gamma-glutamylcysteine synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">gshA</name>
        <name evidence="8" type="ORF">VDA_001304</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4 5 6">
            <text>ATP + L-cysteine + L-glutamate = ADP + gamma-L-glutamyl-L-cysteine + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13285"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58173"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 5 6">Sulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.2" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297837.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001304"/>
    <dbReference type="EnsemblBacteria" id="EEZ40279">
        <property type="protein sequence ID" value="EEZ40279"/>
        <property type="gene ID" value="VDA_001304"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2918">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="967793at2"/>
    <dbReference type="UniPathway" id="UPA00142">
        <property type="reaction ID" value="UER00209"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004357">
        <property type="term" value="F:glutamate-cysteine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006750">
        <property type="term" value="P:glutathione biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00578">
        <property type="entry name" value="Glu_cys_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007370">
        <property type="entry name" value="Glu_cys_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006334">
        <property type="entry name" value="Glut_cys_ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38761">
        <property type="entry name" value="PTHR38761"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04262">
        <property type="entry name" value="Glu_cys_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="SSF55931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01434">
        <property type="entry name" value="glu_cys_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5" id="KW-0317">Glutathione biosynthesis</keyword>
    <keyword evidence="5 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glu_cys_ligase" evidence="7">
        <location>
            <begin position="11"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ40279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="521" mass="59270" checksum="C9A4BF980C319979" modified="2010-01-19" version="1">MDFSQRLQQVSANKDALKKFGRGLEREALRITTDHQLSDQPHPVQLGSALTNKWITTDFAESLLEFITPVSRSVDDLLAQLSDIHQFTYSKMNGERLWPMSMPCFVGDQDDITLAQYGSSNVGRMKTLYREGLKRRYGSVMQIISGVHFNFSFPDEFWDQLFGPQNEQERQESRSVAYFGLIRNYYRFGWLIPYLFGSSPALCGSFLQGKPIKDKFSKIGQGTYYLEKATALRLSDLGYTNNAQSGLKIGFNSLEQYLDGLNKAIRTPSAEFADIGVKVGDEYRQLNSNVLQIENELYAPIRPKRVANSGEKPSEALKRAGVEYIEVRSLDVNPFSPIGVVEDQIRFLDMFLTWAVLSPSSDMTDCELGCWRENWSKVILDGRNPDLVLTIGCHGEQLTLKEWGSRVFTDFAQVAKMLDEANGTTAYQETCERLLGWIEHPERTLSAQLLEQIKQFDGIGKVGDELAKQHAEFMAHRQYQFYNEAQFETEAKESIAKQQQIEANDTVSFDDYLAAYFADIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW02</accession>
    <name>D0YW02_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Cystathionine beta-synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">VDA_001307</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297841.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001307"/>
    <dbReference type="EnsemblBacteria" id="EEZ40282">
        <property type="protein sequence ID" value="EEZ40282"/>
        <property type="gene ID" value="VDA_001307"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4536">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1155802at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04590">
        <property type="entry name" value="CBS_pair_CorC_HlyC_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002550">
        <property type="entry name" value="CNNM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044751">
        <property type="entry name" value="Ion_transp-like_CBS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005170">
        <property type="entry name" value="Transptr-assoc_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03471">
        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01595">
        <property type="entry name" value="DUF21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01091">
        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51846">
        <property type="entry name" value="CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0129">CBS domain</keyword>
    <keyword evidence="6 8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="62"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="92"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="CNNM transmembrane" evidence="11">
        <location>
            <begin position="2"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="10">
        <location>
            <begin position="272"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ40282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="425" mass="47339" checksum="0FBE3E9E311BA0B3" modified="2010-01-19" version="1">MEDISTGVLFALLILMLVLSAYFSGSETGMMALNRYKLRHLANQGHKGAQRVEKLLARPERLIGLILIGNNLVNILASAIATILGMRLYGDAGVAIATGALTLVVLVCSEVTPKTLAAQYPERISYASSILLNALMKILYPLVWIVNGITASFLFLFGLRNKNDGGNPLTSEELRTVVNEAGSLIPRRHQDMLLSILDLENVTVVDVMIPRNEIAAININDDWKSIARQLSHSAHGRIVLYRDTIDEVVGMLRVREAYRMMLDKNEFSKENLLRAADEVYFIPEGTPLNIQLLKFQRNKERIGLIVDEYGDIQGLITLEDILEEIVGEFTTSIAPTLAEEITPQSDGSLLIEGSANIRDLNKSLKWKLPTDGPRTLNGLILEYLEYIPDSPISFRIGNKKMEVVEVSDNMIKLVKVLPMNRKNDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW39</accession>
    <name>D0YW39_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Purine nucleoside phosphorylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_001324</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>adenosine + H(+) + H2O = inosine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:24408"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16335"/>
            <dbReference type="ChEBI" id="CHEBI:17596"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.4"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="4">
            <dbReference type="Rhea" id="RHEA:24409"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>adenosine + phosphate = adenine + alpha-D-ribose 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:27642"/>
            <dbReference type="ChEBI" id="CHEBI:16335"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57720"/>
            <dbReference type="EC" id="2.4.2.1"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="2">
            <dbReference type="Rhea" id="RHEA:27643"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>inosine + phosphate = alpha-D-ribose 1-phosphate + hypoxanthine</text>
            <dbReference type="Rhea" id="RHEA:27646"/>
            <dbReference type="ChEBI" id="CHEBI:17368"/>
            <dbReference type="ChEBI" id="CHEBI:17596"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57720"/>
            <dbReference type="EC" id="2.4.2.1"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="1">
            <dbReference type="Rhea" id="RHEA:27647"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>phosphate + S-methyl-5'-thioadenosine = adenine + S-methyl-5-thio-alpha-D-ribose 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:11852"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58533"/>
            <dbReference type="EC" id="2.4.2.28"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="3">
            <dbReference type="Rhea" id="RHEA:11853"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="5 9">Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001324"/>
    <dbReference type="EnsemblBacteria" id="EEZ40299">
        <property type="protein sequence ID" value="EEZ40299"/>
        <property type="gene ID" value="VDA_001324"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1496">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004000">
        <property type="term" value="F:adenosine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017061">
        <property type="term" value="F:S-methyl-5-thioadenosine phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd16833">
        <property type="entry name" value="YfiH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.140.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003730">
        <property type="entry name" value="Cu_polyphenol_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038371">
        <property type="entry name" value="Cu_polyphenol_OxRdtase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011324">
        <property type="entry name" value="Cytotoxic_necrot_fac-like_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30616">
        <property type="entry name" value="PTHR30616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02578">
        <property type="entry name" value="Cu-oxidase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64438">
        <property type="entry name" value="SSF64438"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00726">
        <property type="entry name" value="TIGR00726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ40299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="243" mass="26547" checksum="1122D2B8779CF3CE" modified="2010-01-19" version="1">MWIKPNWPAPTNVAAISTTRVGGVSLAPFDQLNLGLHVDDNPLAVEQNRQRVMQSCQLTQTPAWLNQIHSPTVLNLSQPLTETPDADGSFTRVSGLACVVMTADCLPVLLCNSEGTEVAAVHAGWRGLAGGVIDNAIAQFSSEPEQIMAWLGPAIGPQAFEVGGEVREQFMAEDPQAHLAFVANPAAEGKWFADLYQLARQRLARHGVTQVYGGEYCTYQDPQFFSYRRAARTGRQASLIWLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW74</accession>
    <name>D0YW74_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5 6">Elongation factor Ts</fullName>
            <shortName evidence="5">EF-Ts</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">tsf</name>
        <name evidence="9" type="ORF">VDA_001359</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the EF-Ts family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297916.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001359"/>
    <dbReference type="EnsemblBacteria" id="EEZ40334">
        <property type="protein sequence ID" value="EEZ40334"/>
        <property type="gene ID" value="VDA_001359"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0264">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1405357at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00050">
        <property type="entry name" value="EF_Ts"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036402">
        <property type="entry name" value="EF-Ts_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001816">
        <property type="entry name" value="Transl_elong_EFTs/EF1B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014039">
        <property type="entry name" value="Transl_elong_EFTs/EF1B_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018101">
        <property type="entry name" value="Transl_elong_Ts_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11741">
        <property type="entry name" value="PTHR11741"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00889">
        <property type="entry name" value="EF_TS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="SSF46934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54713">
        <property type="entry name" value="SSF54713"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00116">
        <property type="entry name" value="tsf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01126">
        <property type="entry name" value="EF_TS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01127">
        <property type="entry name" value="EF_TS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5 6" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="4 5 6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF_TS" evidence="8">
        <location>
            <begin position="71"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Involved in Mg(2+) ion dislocation from EF-Tu" evidence="5">
        <location>
            <begin position="80"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ40334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="281" mass="29741" checksum="20167662D6455E14" modified="2010-01-19" version="1">MATVTAALVKELRERTGAGMMECKKALVEANADIELAIENMRKSGAAKAAKKAGNVAAEGIIIIKEGEGVAALVEVNCQTDFVAKDGNFLGFANEVAEAALAAQSSVEELQAKFEEARVALVAKIGENVSIRRVEYIKGENIATYSHGARIGVVVAGNGDAETLKHIAMHVAASRPEYVTPEDVPAEVVAKEREVQVEIAMNEGKPQAIAEKMVEGRMKKFTGEVSLTGQAFIMEPKKTVGEVLKEAGATVSGFVRLEVGEGIEKQEGLSFAEEVALAQKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW98</accession>
    <name>D0YW98_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase</fullName>
            <ecNumber evidence="10">2.4.1.227</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">murG</name>
        <name evidence="13" type="ORF">VDA_001176</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>di-trans-octa-cis-undecaprenyl diphospho-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UDP-N-acetyl-alpha-D-glucosamine = di-trans-octa-cis-undecaprenyl diphospho-[N-acetyl-alpha-D-glucosaminyl-(1-&gt;4)]-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + H(+) + UDP</text>
            <dbReference type="Rhea" id="RHEA:31227"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:61387"/>
            <dbReference type="ChEBI" id="CHEBI:61388"/>
            <dbReference type="EC" id="2.4.1.227"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="10">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Peripheral membrane protein</topology>
            <orientation evidence="10">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the glycosyltransferase 28 family. MurG subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.227" evidence="10"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001176"/>
    <dbReference type="EnsemblBacteria" id="EEZ40154">
        <property type="protein sequence ID" value="EEZ40154"/>
        <property type="gene ID" value="VDA_001176"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0707">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051991">
        <property type="term" value="F:UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050511">
        <property type="term" value="F:undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030259">
        <property type="term" value="P:lipid glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00033">
        <property type="entry name" value="MurG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006009">
        <property type="entry name" value="GlcNAc_MurG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007235">
        <property type="entry name" value="Glyco_trans_28_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004276">
        <property type="entry name" value="GlycoTrans_28_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04101">
        <property type="entry name" value="Glyco_tran_28_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03033">
        <property type="entry name" value="Glyco_transf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01133">
        <property type="entry name" value="murG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 10" id="KW-0132">Cell division</keyword>
    <keyword evidence="1 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 10" id="KW-0133">Cell shape</keyword>
    <keyword evidence="9 10" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3 10 13" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 10" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_transf_28" evidence="11">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_tran_28_C" evidence="12">
        <location>
            <begin position="141"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="UDP-N-acetyl-alpha-D-glucosamine binding" evidence="10">
        <location>
            <begin position="219"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="200"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="244"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF04101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ40154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="311" mass="33114" checksum="1707D2156E389AAA" modified="2010-01-19" version="1">MEADLVPKHGIEIDFIKVKGLRGQGIARLLTAPFKIVGAILQARKYIKAWQPDVVLGMGGYVSGPGGVAAWLSGVPVVLHEQNAVAGLTNQWLSKIASAVLQAFPGAFKDKEVVGNPVRHDVTVLPPPAERFSEHQGPIRILVMGGSQGARILNQTMPKVAALLGDKVTIWHQAGKGAAEQTEADYQANNAGSHKVTEFIDDVAAAYSWADIVVCRSGALTVSELSAAGVGAIFVPFMHKDRQQALNAEHLVECGAAKMIEQMDLTAEGLAQQLEQLDRPALEQMAQAARDAAILDADIRVANVIKSLAKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWC5</accession>
    <name>D0YWC5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Oligopeptide ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001388</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297979.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001388"/>
    <dbReference type="EnsemblBacteria" id="EEZ40363">
        <property type="protein sequence ID" value="EEZ40363"/>
        <property type="gene ID" value="VDA_001388"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0444">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1101128at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="9"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="50"/>
            <end position="57"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="295" mass="33257" checksum="8582842C5F90FC26" modified="2010-01-19" version="1">MNDLQSPLLEVKNLKVAFANESGNKQNQWQQILHGVSFSVYKGRTLGLVGESGCGKSITALSIMGLLPQPYSKITSGSIVYQNQELTQLPSQQRYQLRGDRISIIFQDPMTALNPVHTIGQQICEVLALHRPELAKKQRWHHAIELLEKVQIPNPQLRIREYPHHLSGGMRQRVMIAMALACQPDILICDEPTTALDVTVQASILDLMHDLQQETQMAMIFITHDLGVVAEICDDVAVMYGGKIVEYSDVFELFDHPKHPYTKRLLGLMPKLTDKPKQLIDIKPIDTTLFPEFQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWC9</accession>
    <name>D0YWC9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA polymerase III subunit alpha</fullName>
            <ecNumber evidence="2">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_001373</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297951.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001373"/>
    <dbReference type="EnsemblBacteria" id="EEZ40348">
        <property type="protein sequence ID" value="EEZ40348"/>
        <property type="gene ID" value="VDA_001373"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0587">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="561611at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1600">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011708">
        <property type="entry name" value="DNA_pol3_alpha_NTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041931">
        <property type="entry name" value="DNA_pol3_alpha_thumb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040982">
        <property type="entry name" value="DNA_pol3_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029460">
        <property type="entry name" value="DNAPol_HHH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004013">
        <property type="entry name" value="PHP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003141">
        <property type="entry name" value="Pol/His_phosphatase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016195">
        <property type="entry name" value="Pol/histidinol_Pase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004805">
        <property type="entry name" value="PolC_alpha"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32294">
        <property type="entry name" value="PTHR32294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07733">
        <property type="entry name" value="DNA_pol3_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17657">
        <property type="entry name" value="DNA_pol3_finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14579">
        <property type="entry name" value="HHH_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02811">
        <property type="entry name" value="PHP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00481">
        <property type="entry name" value="POLIIIAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89550">
        <property type="entry name" value="SSF89550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00594">
        <property type="entry name" value="polc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="5 10" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="POLIIIAc" evidence="9">
        <location>
            <begin position="7"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ40348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="1159" mass="129988" checksum="9F73D860C6C1F6B9" modified="2010-01-19" version="1">MAEPRFIHLRVHSDFSMIDGLAKVKPIIKKASELQMPALAITDFTNLCGLVKFYYAAHDAGIKPIIGADFKVQSEELGDELFDLTILAANNEGYKNLTLLISEAYQRGHVQHQPVIDKEWLIKHKDGLILLSGGKTGDVGKALLKGNQNMVEQCVAFYQTYFSDSYYLELVRTGRPDEEAYLHFAIELAEKAQLPVVATNDVRLLSADQFEAHEIRVAIHDGYTLADPNRPKNYSAQQYLRSEEEMCELFADIPEALENSVEIAKRCNVTVRLGEYFLPNFPTGELSTEDFLVVKSKEGLEERLEFLFPDPDIRAERRPEYDERLEVELEVINQMGFPGYFLIVMEFIQWSKDNGVPVGPGRGSGAGSLVAYALKITDLDPLEFDLLFERFLNPERVSMPDFDVDFCMDKRDQVIDHVADMYGRDAVSQIITFGTMAAKAVIRDVGRVLGHPYGFVDRISKLVPAEPGMTLAKAFDAEPQLQQSYDSDEEVKDLIDMCRILEGVTRNAGKHAGGVVISPTTITDFAPLYCDAEGHHPVTQFDKNDVESAGLVKFDFLGLRTLTIIDWALGMINPRLEAQGEDPVNIAAIPMADQKSFTMLQRSETTAVFQLESRGMKDLIKRLQPDCFEDMIALVALFRPGPLQSGMVDNFIDRKHGREAVSYPDEKWQHESLKDILDPTYGIILYQEQVMQIAQVLAGYTLGGADMLRRAMGKKKPEEMAKQRAVFEAGAIKNGVDGELSMKIFDLVEKFAGYGFNKSHSAAYALVSYQTLWLKAHYPAEFMAAVMTADMDNTDKIIGLVDECHRMKLKLLPPDVNKGLYRFNVDDQGAIVYGIGAVKGVGEGPIENIIAAREAGGHFKDLFDFCARIDTKKVNKRVLERLIKSGAMDRLGPNRASMMASLDDAIRAASQHHQAEAFGQTDMFGVLTEAPEEVEHKYANIPEWPDKVWLEGERETLGLYLTGHPINSYLSELKHYTTWRLKDAQPTRRDGAATVAGLVIAARVMTTKRGTRIGLLTLDDRSGRMEVMLFSEALERYLDLIETDRIVVVTGQVSFDDYNGGLRMSAREVLDISDAREKHLRGLAISVTEQQIDDKFFARFSEILEPHKAGTVPVNVYYQRSNARAKLTLGTEWRITPADQLISDLKILLGEKQVELEFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWD2</accession>
    <name>D0YWD2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 14">D-alanine--D-alanine ligase</fullName>
            <ecNumber evidence="6 14">6.3.2.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">D-Ala-D-Ala ligase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">D-alanylalanine synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">ddl</name>
        <name evidence="18" type="ORF">VDA_001376</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 14">Cell wall formation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>ATP + 2 D-alanine = ADP + D-alanyl-D-alanine + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:11224"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57416"/>
            <dbReference type="ChEBI" id="CHEBI:57822"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="15">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="15">Binds 2 magnesium or manganese ions per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4 14">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="14">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 14">Belongs to the D-alanine--D-alanine ligase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.4" evidence="6 14"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297963.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001376"/>
    <dbReference type="EnsemblBacteria" id="EEZ40351">
        <property type="protein sequence ID" value="EEZ40351"/>
        <property type="gene ID" value="VDA_001376"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1181">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="764798at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008716">
        <property type="term" value="F:D-alanine-D-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00047">
        <property type="entry name" value="Dala_Dala_lig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000291">
        <property type="entry name" value="D-Ala_lig_Van_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005905">
        <property type="entry name" value="D_ala_D_ala"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011095">
        <property type="entry name" value="Dala_Dala_lig_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011127">
        <property type="entry name" value="Dala_Dala_lig_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07478">
        <property type="entry name" value="Dala_Dala_lig_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01820">
        <property type="entry name" value="Dala_Dala_lig_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039102">
        <property type="entry name" value="Ddl/VanB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01205">
        <property type="entry name" value="D_ala_D_alaTIGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00844">
        <property type="entry name" value="DALA_DALA_LIGASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 14" id="KW-0133">Cell shape</keyword>
    <keyword evidence="13 14" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="14" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 14 18" id="KW-0436">Ligase</keyword>
    <keyword evidence="15" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12 15" id="KW-0464">Manganese</keyword>
    <keyword evidence="15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11 14" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="17">
        <location>
            <begin position="99"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR039102-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EEZ40351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="303" mass="33380" checksum="17530B7CA3D53728" modified="2010-01-19" version="1">MRIGVLYGGDSSEREVSLKSGTRIIAAIESLGHEAIHLDPRYIDLSMLGFYKLDKVFIALHGGMGESGHVQSLLDILQIPYIGSGVLASAISLNKLKTKEIWQANGLITAPWVLVQKTMPQVDIMALCSELTFPVVVKPLNQGCSIGVAKADNEVQLWDALLAAFEYDTEVLVEQFIVGREYTCAVLNGEALPVVQICSEEFFDWNAKFGTQSATYHCPSDLTAIEEQTMQETILAAYQALGCRGWGRIDVLLTEHNDVYLIEMNTIPGMTERSVFPMAAAQVGLSYEALIEQLLDHAQFDTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWI0</accession>
    <name>D0YWI0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001439</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the UbiH/COQ6 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298066.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001439"/>
    <dbReference type="EnsemblBacteria" id="EEZ40413">
        <property type="protein sequence ID" value="EEZ40413"/>
        <property type="gene ID" value="VDA_001439"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0654">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="867226at2"/>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010971">
        <property type="entry name" value="UbiH/COQ6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01988">
        <property type="entry name" value="Ubi-OHases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="4">
        <location>
            <begin position="7"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="386" mass="43231" checksum="B419FE7798F8F31C" modified="2010-01-19" version="1">MEPFDFVVAGGGMVGAATAIGLAQQGFRVAVVESHQPVPFHSSQPADLRVSAISPNSISLLQQLGAWDTVMAMRVCPFKRLETWDAPECRTRFHADELNVPWLGYIVENRVIQLALWQQFESYPNITLLCPNKIVTMQSVDNGYQLLLDNEQQLSTKILIGADGANSFVRQQAGIGITAWDYRQHCMLIHVETELAQQDITWQQFTPQGPRSFLPLPGHQGSLVWYDAPERIRKLSHMPAEQLEQEIYRHFPAELGKVTVVNRGSFPLTRRHAQCYAQSGVVLLGDAAHTINPLAGQGVNLGFKDVLVLLDEVEKAGANWAQATTYQRYERRRRPDNLLMQSGMDLFYTVFSNTLPPLQLLRNVGLRLADKAGPVKKQVLKYAMGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWK9</accession>
    <name>D0YWK9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">O-antigen chain length determinant protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_001500</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298165.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001500"/>
    <dbReference type="EnsemblBacteria" id="EEZ40474">
        <property type="protein sequence ID" value="EEZ40474"/>
        <property type="gene ID" value="VDA_001500"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3765">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009103">
        <property type="term" value="P:lipopolysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003856">
        <property type="entry name" value="LPS_length_determ_N_term"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02706">
        <property type="entry name" value="Wzz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="28"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="326"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="Wzz" evidence="7">
        <location>
            <begin position="12"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ40474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="352" mass="40061" checksum="99F026C4649F0A4C" modified="2010-01-19" version="1">MSSDEQSIYQDNQLNLLNIFRVLWTRKLIIIISTIIGIVLALIVSIYSAQWWESSAEITKPQYSDYAVFISSADQLTTGSNPSESLKSIINIEKNYNSFINILTSKTNKIDFLQQSNIIKSYFIRDGVKTDIQKDKALDLWAEKIIVKKESLILNKSSYIVIAQANTLDDSFKLLNNYIKFTKNKYNSDVLLSLETFKRIELLNLKKQLDYNISYTLDIKKLKEQKAQLALNIAEESGIESPLNNYFEKGSSFNIALGAKALRAEKNVISSLKDLAIFNDKITLLSSQLNYLNNVKLSNLENNAFFSYIQTEHKNPNKIAPSKKTFILVFSLLFACIGIVIALVIEIFSKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWZ2</accession>
    <name>D0YWZ2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cap4_nuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002045</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299263.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41013">
        <property type="protein sequence ID" value="EEZ41013"/>
        <property type="gene ID" value="VDA_002045"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG503181E">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="441318at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025382">
        <property type="entry name" value="Cap4_endonuclease_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14130">
        <property type="entry name" value="Cap4_nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cap4_nuclease" evidence="1">
        <location>
            <begin position="21"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="374" mass="43450" checksum="BA4D1B8F8C4704E7" modified="2010-01-19" version="1">MHIVTDINLKPNFAQADKQDEDAGALTFAKYWYQYNWALLHLFNQMPNFNNCSITMETHEDVMFISNIDYNETKIDLFQVKERSKSGNITSNVICRGSKDKPAIISKIIKNITKERLVKRLNSIALVSSTDYSFKLKNEDDKISSYHSVNFNHLSDEVKNEIKKAVLRDLDISEIPNFLYFIRGMQTTSKDESTLLIIGIIAKYIDSIDPNSSSKPKLIYDAITTELLKIGCSTLKYNNWDDFVKNKTITKKQIEKIIQRRTTREGFTDFESVWIKITNEMSNDANYAKLPIKSKSKMKKKVREYYGLKMTQTNLMFDSFSEKVNELFELSSKEDLYEIIIDIKSNLLKDEKYSDIFNEELLEPAILLEISENI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX25</accession>
    <name>D0YX25_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative sodium/alanine symporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_001900</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell inner membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298899.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001900"/>
    <dbReference type="EnsemblBacteria" id="EEZ40868">
        <property type="protein sequence ID" value="EEZ40868"/>
        <property type="gene ID" value="VDA_001900"/>
    </dbReference>
    <dbReference type="GeneID" id="57341975"/>
    <dbReference type="eggNOG" id="COG1115">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="883596at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015655">
        <property type="term" value="F:alanine:sodium symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001463">
        <property type="entry name" value="Na/Ala_symport"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30330">
        <property type="entry name" value="PTHR30330"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01235">
        <property type="entry name" value="Na_Ala_symp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00175">
        <property type="entry name" value="NAALASMPORT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00835">
        <property type="entry name" value="agcS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00873">
        <property type="entry name" value="NA_ALANINE_SYMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0769">Symport</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="69"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="104"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="152"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="192"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="219"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="245"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="314"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="356"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="384"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="416"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ40868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="468" mass="49738" checksum="BB54F0A3478ED4AA" modified="2010-01-19" version="1">MNPLHDTIFSFLKAFDNLVWGPPLLILLVGTGMYLTFRLGFIQIRYLPLALRYVFGGKKDKDAQGEGDVSSFAALCTALSATIGTGNIVGVATAIKLGGPGALFWMWLAALFGMATKYAECLLAVKYREQDANGQMLGGPMYYLDKGVGSKWLAKLFALFAIGVACFGIGTFPQANAIVEAAQISFSVPKEITVVILTVLVAMVTLGGIQSISSVASKVVPLMAGFYIIACLIVLGTNVSHLPEAVSLVIESAFTGHAATGGFLGAGIMLAIQSGIARGVFSNESGLGSAPIAAAAAQTESSVRQGLVSMTGTFFDTIIICTMTGLTLVVTGAWQTDLAGATMTTHAFSMGLNSDYYGPLMVSIGLMFFAFTTILGWNYYGERCVAYLFGVKAILPYKLFFLVLIAAGAFMKLDMIWIIADIVNGLMAIPNLIGLVCLRHVIIAESQTFFAQLKAEREQEKQQAAQAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-06-02" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX39</accession>
    <name>D0YX39_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Accessory colonization factor AcfD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001907</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298912.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001907"/>
    <dbReference type="MEROPS" id="M98.001"/>
    <dbReference type="EnsemblBacteria" id="EEZ40875">
        <property type="protein sequence ID" value="EEZ40875"/>
        <property type="gene ID" value="VDA_001907"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3064">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="40288at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025385">
        <property type="entry name" value="DUF4092"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035423">
        <property type="entry name" value="M60-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042279">
        <property type="entry name" value="Pep_M60_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031161">
        <property type="entry name" value="Peptidase_M60_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13322">
        <property type="entry name" value="DUF4092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17291">
        <property type="entry name" value="M60-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13402">
        <property type="entry name" value="Peptidase_M60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01276">
        <property type="entry name" value="M60-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51723">
        <property type="entry name" value="PEPTIDASE_M60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M60" evidence="2">
        <location>
            <begin position="1086"/>
            <end position="1383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="1509" mass="168700" checksum="FB8395AF10361D07" modified="2010-01-19" version="1">MHLKLLSLAITAALLTGCNGDSNSQNTDLPLTPLDPSIPVKPEQPLIPLEPSIPVEPEIPEPPVEPELPEPPTEPDTIPPSVLDPAIKIHKGGLQLSGKQLVGDISCNGQELALNGQFTFKDGDDIRCNFGSIELFSQQAPQPRSLHSDAQKVIHFDIEHFLHDGAVDNTVQVLNKIDTCKSDNNKVCLDVINSYDIATLYNSTDTEAVKEFINPSSEQVTEEVDKAPSSHVDVTLKPEVTPGTSTDLNSQFVSASAESAYQYKPSVDNQEITVAKLLDAKGLPIAGVHYYTPSSRGVTDSQGQIEYIWGEEITFGIDTFTFGSVKGNQLSYQLTDVTENSLVKQNIDSLIERYSKNLHDHREFDTKVHQIFALYPNAINEIINISLPNGAKIEGTNFHVPNEFEYQFDSGLAKEIDEQLKQPKSLWAKQTKIVKAHGSNINATLHQIYSGVQQFHVFHDVGSYYGASGFARLMRNLNISNTAFPILMPRMDSNYWLPFGKEQAWTREFKPHIVDATTIDADSKVTMLRPPKVSEDNATFNLPGISTGQIGKGSIVFMGSGHYPIVLSCPDSYWGNKSLSIKDQQCTYSINNNIVDPTTDRQFDNGSMQRFFKNLFTWLEPSYQNGQNAINVATNIELAPKFDHGHQSWLPKYEFFINKSYNVSLERITSGNFSGINPETTPILLLQSYEIGAFGDGTTTKNISDLSQPKLTVNDVNDLIQYVNAGGHIVFFDAIEQVNPEPIAKLADMAGVSLGGANVAQAKTTQAYCGSSYYCHGSGVKPNVHAVTEHDLVVYERFETLNDDASKIVINSDGTITWPAPNKMPKLEVAKYTTPYMPLTIDGIPQERFAFFQVKSEDEKRAAIHELQVAFPGVKVCQDDYEFEVNCIEFRKGHGIPSFGNYQRANYERYSISPKVIDSMVEAANLGTNLTKLYQHELYYRTRGEQGHRLSLTELNQTYDNTSVWMWNDEPYRYDNSVEDELGFKTAVDYLNCYTNNQHQGGIECSVDKQQALIKYGFLHKNGELNPSYPLNYQEKPLTRIMLGRSYWDLDIKVDTTQYPGRPAFTNGTQTVTVSTLNNAVTGTVNNMQSTGLWAHQHQQVQVSGGVPATITVSLIDDLTGLEQHEVALNRPPRVQKSFNYDGSNLSFRVPYGGLIYIKPHSNIEGTAEFSFSGVATAAFWKDNQWMYGKASDVPLAEIDTGHVIYTTPVENIEQQDIQIFVDEMNKFANSASDFYGRDEVVSVGKHRRFTYQDLADHRHRFVNDIQISIGAAHSGYPVQSTTYNKGNKIPTTPTNDWLLWHEIGHNLASAPFSMTGGTEVTNNILALYMQEQRPEPNNKMSRVESDIQKMPLLFSRYNKHVWSNGDAGIRLVMFAQLKLWAENHFRIDNWYSEKDLLTIYNQDQGWNMFKLMHRKSRGDSIGDQGINYCSSSDTGLSGGDLLMVCSSYVSGFDLSNFYTLWNPSESMNILPNGDKLYSGGITSKGYQVLNQIPNLKQPETSPESITHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX55</accession>
    <name>D0YX55_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001828</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298780.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001828"/>
    <dbReference type="EnsemblBacteria" id="EEZ40796">
        <property type="protein sequence ID" value="EEZ40796"/>
        <property type="gene ID" value="VDA_001828"/>
    </dbReference>
    <dbReference type="GeneID" id="57342056"/>
    <dbReference type="eggNOG" id="COG4191">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="692375at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004673">
        <property type="term" value="F:protein histidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="169"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="4">
        <location>
            <begin position="246"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="448" mass="50627" checksum="B79E1C87A33EBCA6" modified="2010-01-19" version="1">MKPLIPPRLRRRVLVTSVAIIVLITSALAGVINQLYSQSYMASYSSELVAQLPMVVAQLNRAGLIKDVDKWISSVDPSKTDYISVVCNQNDDTVWLSNPEKLHNLTNICTHIPDEINTPTLVKFPNHDSYIAYNLSRDKENGKVFQLVVLRSGQNYEASLSQLHKRTTFYLGLFVLIAITFLIAAFHWSFQPLRKLANQLNEMSEAERNQLDSDYPMELQEITKALNRLILLSNDQKGRYRHAMDDLAHSLKTRLAATNALLDDKELSRAELNHRIMEQISQMDDLVQYQLKRAMMGQQGLQRSKTELKPAVETFGRMLSKIYGDKSVKLRCTFPDKQLVPINKDDLMELLGNLLENAYRFCISEVAISVIEKSNLCVIRIEDDGPGVKPEMREAIFQRGVRADQLNPGQGIGLSVCHEIVSSYQGTIHVESSQLEGAAFIIKIPKQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX59</accession>
    <name>D0YX59_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NADH dehydrogenase</fullName>
            <ecNumber evidence="4">1.6.99.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001848</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NADH dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.6.99.3" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298809.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001848"/>
    <dbReference type="EnsemblBacteria" id="EEZ40816">
        <property type="protein sequence ID" value="EEZ40816"/>
        <property type="gene ID" value="VDA_001848"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1252">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="403436at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003954">
        <property type="term" value="F:NADH dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006116">
        <property type="term" value="P:NADH oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045024">
        <property type="entry name" value="NDH-2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43706">
        <property type="entry name" value="PTHR43706"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="3">
        <location>
            <begin position="3"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="429" mass="47323" checksum="4558E6EAA292DEDD" modified="2010-01-19" version="1">MTRIIVVGGGAGGLELATKLGRTLGRKRRAQITLVDRKASHLWKPLLHEVATGSMDAGVDAISYRAHAKNHSFDFQMGSLQAVDREAKKITLAALYNKQNELLMPERELEYDILVLAIGSISNDFNTPGVRENCIFLDSPEQAHRFRTQMNNQFLKLHANKDQQTVDIAIVGAGATGVELSAELHNAVKELQNYGFGDLDSSRLNVNLVEAGERILPALPPRISQAAHSELTKLGVHVRTATMVNKADETGLTTKDGEHIPAQIMVWAAGIKVPDFMKDIAGLETNRINQLVVKPTLQTTRDDDIFVIGDLASCQQEDGSFVPPRAQAAHQMASRCFSNIVAKLNDRTLKPYVYKDHGSLVSLSRFSTVGSLMGNLTKGSMMVEGRIARVVYISLYRMHQMALHGVFKTGLMMLVSRINRVLRPNLKLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXB5</accession>
    <name>D0YXB5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Leucine-responsive regulatory protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001655</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298455.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001655"/>
    <dbReference type="EnsemblBacteria" id="EEZ40628">
        <property type="protein sequence ID" value="EEZ40628"/>
        <property type="gene ID" value="VDA_001655"/>
    </dbReference>
    <dbReference type="GeneID" id="57342262"/>
    <dbReference type="eggNOG" id="COG1522">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1844486at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000485">
        <property type="entry name" value="AsnC-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019888">
        <property type="entry name" value="Tscrpt_reg_AsnC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019887">
        <property type="entry name" value="Tscrpt_reg_AsnC/Lrp_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019885">
        <property type="entry name" value="Tscrpt_reg_HTH_AsnC-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01037">
        <property type="entry name" value="AsnC_trans_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00033">
        <property type="entry name" value="HTHASNC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00344">
        <property type="entry name" value="HTH_ASNC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00519">
        <property type="entry name" value="HTH_ASNC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50956">
        <property type="entry name" value="HTH_ASNC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH asnC-type" evidence="4">
        <location>
            <begin position="12"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="164" mass="18861" checksum="18AE89AD54129356" modified="2010-01-19" version="1">MVDTKKKPSKELDRIDRNILNELQKDGRISNVELSKRVGLSPTPCLERVRRLERQGYISGYTALLNPQYLDASLLVFVEITLNRGAPDVFEQFNKSVQELEDIQECHLVSGDFDYLLKTRVSDMSAYRKLLGETLLRLPGVNDTRTYVVMEEVKQSNNLVIKTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXL5</accession>
    <name>D0YXL5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyl-accepting chemotaxis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001756</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298637.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001756"/>
    <dbReference type="EnsemblBacteria" id="EEZ40724">
        <property type="protein sequence ID" value="EEZ40724"/>
        <property type="gene ID" value="VDA_001756"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502Z7W2">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1450038at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021307">
        <property type="entry name" value="DUF2884"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11101">
        <property type="entry name" value="DUF2884"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019814" evidence="1">
        <location>
            <begin position="19"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="247" mass="27308" checksum="71C9B62662CE2A52" modified="2010-01-19" version="1">MKKVVLAGLLLSSSSVWAQSCPVSVPNDIHVNDGKVSVYVAGKPKLVIDENNNVFIDGKKLDLNAMQQQAVAAYSNGVQEFLPQMAGMADTGMALASDVMDQVSKSLGSEESFAKVQTLIKQYGEQAKAKFYNEKGEFVMPANTFENMDTQWQTEFEQAMKQLSVESMAGLFSALSNEMKNGEINLTEMQSKFSELKTNISEQVQKHSKEMAAQSNQLCTSVEGLAKEENQLQQLIPQLKDIKMFEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXN4</accession>
    <name>D0YXN4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">META domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001731</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001731"/>
    <dbReference type="EnsemblBacteria" id="EEZ40701">
        <property type="protein sequence ID" value="EEZ40701"/>
        <property type="gene ID" value="VDA_001731"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3187">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3895">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005184">
        <property type="entry name" value="DUF306_Meta_HslJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038670">
        <property type="entry name" value="HslJ-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03724">
        <property type="entry name" value="META"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019817" description="META domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="domain" description="META" evidence="2">
        <location>
            <begin position="221"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="339" mass="37396" checksum="EE7C41F2BA24C0EF" modified="2010-01-19" version="1">MKCLRAIMTGTAFIASTSVIATPSLMDCLQNEHSSTCKYQMAAALSKDGSSLTVPKTQAFSLFALKNTIYHGIDGIEASFRLQNGIWVGEPYQPGGSIMPQVILVPDIIAKGDLTADQQDDAVVMLDFSPGGTGQYLYLAVMENRLGQPINIATQFVGDRVRVKDLHIENGKIIMTAIEPSSTDAMCCPGNVVKRIWQLQNHQLVEEKSQESVQRLTLNLLDNSGWKLDSWQYGEPVSANTHITLLYQDEHLVGKTACHSYSIAVRDTLRPGFINLAADYSTMDTTECTTEQQDADKRYLEQLAHVNQFTFFAGRLTLSYNSNGHLGVMIFSPQTSSEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXR8</accession>
    <name>D0YXR8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8 9">Nicotinate phosphoribosyltransferase</fullName>
            <shortName evidence="8">NAPRTase</shortName>
            <ecNumber evidence="4 8 9">6.3.4.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">pncB</name>
        <name evidence="12" type="ORF">VDA_002081</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 9">Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8 9">
            <text>5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O + nicotinate = ADP + diphosphate + nicotinate beta-D-ribonucleotide + phosphate</text>
            <dbReference type="Rhea" id="RHEA:36163"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32544"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57502"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8 9">Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1.</text>
    </comment>
    <comment type="PTM">
        <text evidence="8 9">Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8 9">Belongs to the NAPRTase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.21" evidence="4 8 9"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299374.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002081"/>
    <dbReference type="EnsemblBacteria" id="EEZ41049">
        <property type="protein sequence ID" value="EEZ41049"/>
        <property type="gene ID" value="VDA_002081"/>
    </dbReference>
    <dbReference type="GeneID" id="57341807"/>
    <dbReference type="eggNOG" id="COG1488">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="241792at2"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00457"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004516">
        <property type="term" value="F:nicotinate phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004514">
        <property type="term" value="F:nicotinate-nucleotide diphosphorylase (carboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01401">
        <property type="entry name" value="PncB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00570">
        <property type="entry name" value="NAPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041525">
        <property type="entry name" value="N/Namide_PRibTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040727">
        <property type="entry name" value="NAPRTase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006406">
        <property type="entry name" value="Nic_PRibTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007229">
        <property type="entry name" value="Nic_PRibTrfase-Fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036068">
        <property type="entry name" value="Nicotinate_pribotase-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11098">
        <property type="entry name" value="PTHR11098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04095">
        <property type="entry name" value="NAPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17767">
        <property type="entry name" value="NAPRTase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000484">
        <property type="entry name" value="NAPRT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51690">
        <property type="entry name" value="SSF51690"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01514">
        <property type="entry name" value="NAPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6 8 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 8" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7 8 9" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NAPRTase_N" evidence="11">
        <location>
            <begin position="14"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="NAPRTase" evidence="10">
        <location>
            <begin position="172"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphohistidine; by autocatalysis" evidence="8">
        <location>
            <position position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00570"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF17767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ41049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="399" mass="45363" checksum="E5C1498663D67995" modified="2010-01-19" version="1">MNHTGHNGVIESLLDTDAYKLHMQQAIFHQYPNVEAVAEFHCRSKEDLRPYCQQIKAEIEKISELSFTDDELAYLSTLSFFQADYLAYLKDFKLNAANVFVDDSGDQLSIKITGKWLDVILWEVPLLAIICEVRCSHRYPNASAADAIAQLETKIERFYQNAQQNNIDLSQFALVDFGSRRRFSKAVHHQVVDYLAKNMPEFKGTSNYYLAFTRGLTPVGTQAHEWFQGHQQLSGELADSQQLALNRWLQEYPDSLGIALTDCINMDAFLRDFDLRLSERFDGLRHDSGDPISWGEKAIAHYQDLGIDPKTKSLVFSDSLTLDKALNIYKHFADRINVSFGIGTQLTCDLPGVETLNVVLKLTECQGRPVAKISDEPGKIMCRDEDYLDQLRTAFKIAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXU8</accession>
    <name>D0YXU8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidase T</fullName>
            <ecNumber evidence="5">3.4.11.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Aminotripeptidase</fullName>
            <shortName evidence="5">Tripeptidase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Tripeptide aminopeptidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">pepT</name>
        <name evidence="9" type="ORF">VDA_002111</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Cleaves the N-terminal amino acid of tripeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>Release of the N-terminal residue from a tripeptide.</text>
            <dbReference type="EC" id="3.4.11.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5 7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5 7">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase M20B family.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.4" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299468.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="MEROPS" id="M20.003"/>
    <dbReference type="EnsemblBacteria" id="EEZ41079">
        <property type="protein sequence ID" value="EEZ41079"/>
        <property type="gene ID" value="VDA_002111"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2195">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1015417at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045148">
        <property type="term" value="F:tripeptide aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043171">
        <property type="term" value="P:peptide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00550">
        <property type="entry name" value="Aminopeptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001261">
        <property type="entry name" value="ArgE/DapE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010161">
        <property type="entry name" value="Peptidase_M20B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42994:SF1">
        <property type="entry name" value="PTHR42994:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037215">
        <property type="entry name" value="Peptidase_M20B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01882">
        <property type="entry name" value="peptidase-T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00758">
        <property type="entry name" value="ARGE_DAPE_CPG2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00759">
        <property type="entry name" value="ARGE_DAPE_CPG2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 5" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2 5" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="M20_dimer" evidence="8">
        <location>
            <begin position="207"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 6">
        <location>
            <position position="80"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5 6">
        <location>
            <position position="174"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <position position="140"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <position position="380"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR037215-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR037215-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="410" mass="44891" checksum="5E53B91CA3FA2FE7" modified="2010-01-19" version="1">MDNLIKRFLRYVSFDTQSNGANTNCPSTPGQLTFAQELQQEMINIGLQDVSLDENGYLMGHLPANVNYDVPAIGFVAHMDTAPDASGKNVKPQIVENYRGGDIALGIGDEVLSPIQYPDLNKLHGHNIITTDGSTLLGADNKAGIAEIMTAIEVLVANPELPHGKICVGFTPDEEIGRGANLFDVEKFGAQWAYTIDGGPVGELEFENFNASSAQVIVHGINVHPGTAKGKMINSMNIAAKFQLMMPADETPECTEGYEGFYHLTSMQSSVAKTQLNYIIRDFDRDGLAQRKAFMQQKVDELNAELNKKGRIELSITDSYYNMREMVEPYPHIIELAKQAMVECDIEPDIKPIRGGTDGARLSFMGLPCPNIFTGGYNFHGIHEFITVEGMEKAVNVIVKLAGKTALSNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXU9</accession>
    <name>D0YXU9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002112</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299470.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002112"/>
    <dbReference type="EnsemblBacteria" id="EEZ41080">
        <property type="protein sequence ID" value="EEZ41080"/>
        <property type="gene ID" value="VDA_002112"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502Z8T7">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021370">
        <property type="entry name" value="DUF2987"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11205">
        <property type="entry name" value="DUF2987"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="199" mass="22773" checksum="805899DD302FE23C" modified="2010-01-19" version="1">MNFRNTLYLGLALIGNYVFAQDLNLRYAELYNKQRYNQESSLVEVRSFLIDKQSQQACVIKQIIMYSKQHSEQLPLLATGEVKIPVDAHLRKVNPDIKISVADGQDCNFHYQFTSKRTPHNTITGKEALQYQMAFSQLMTNLSGRVGSWFVPKVTGVEVHFKDSSSTDKLWINEFTATDNKHYELAIESITPLFDQGSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY36</accession>
    <name>D0YY36_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002199</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299636.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41167">
        <property type="protein sequence ID" value="EEZ41167"/>
        <property type="gene ID" value="VDA_002199"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031YJC">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2135828at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="176"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="218" mass="24931" checksum="4616F13DCE49E07F" modified="2010-01-19" version="1">MNLDLVAFVEKLLEFLDSKNYIAILLVLAFSVLVNLPKITEYYLSHKKRRLDSLIKLKDLDELDNRLKSHIKSEIEVEVFRLTHNVRISAVLLGGLLSLKERVGSQVSFAHILRCSCLVPDLSKVNEPNFQIKIHKLDYAYVVYNTVFGLLIFFVGFFLLTYSLAMLHSAPNFQSLFVSCLMLLVGFGMLTQTTPVYSTRIINKQLSENQLDLDEKSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY52</accession>
    <name>D0YY52_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Regulatory protein RecX</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_002215</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RecX family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299665.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002215"/>
    <dbReference type="EnsemblBacteria" id="EEZ41183">
        <property type="protein sequence ID" value="EEZ41183"/>
        <property type="gene ID" value="VDA_002215"/>
    </dbReference>
    <dbReference type="GeneID" id="57341641"/>
    <dbReference type="eggNOG" id="COG2137">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2025178at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006282">
        <property type="term" value="P:regulation of DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003783">
        <property type="entry name" value="Regulatory_RecX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33602">
        <property type="entry name" value="PTHR33602"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02631">
        <property type="entry name" value="RecX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="262" mass="30170" checksum="4F042FDDCCF92EEE" modified="2010-01-19" version="1">MKKIQPAKTLQNVINSAIYHLNLRDHSISELKTKLEAKTDNQEWVDTVIAQMKGYGYLKEDLPFAIHFCETSYANEYGKRYMIEKLKQKGISETDITDALERVSHQQQRSEYDLVVERLSRIEDFSHTTKEKVFNTLLKRGFSLNDITHAIAEHPAGNTLLEKAVIKGQNANLRNEIIKLAKKLKGAALIRRELSMKHIDVSEFDQIIDELTQSGEIDFYANCITLLAKKRYDLTDYKEKNKAYAYLSSHGFSSDEIKCAFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY85</accession>
    <name>D0YY85_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Amino acid ABC transporter amino acid-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002248</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299731.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002248"/>
    <dbReference type="EnsemblBacteria" id="EEZ41216">
        <property type="protein sequence ID" value="EEZ41216"/>
        <property type="gene ID" value="VDA_002248"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0834">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="685252at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00062">
        <property type="entry name" value="PBPb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="PBPb" evidence="2">
        <location>
            <begin position="38"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="342" mass="38340" checksum="26EAD8EBC8463AFD" modified="2010-01-19" version="1">MVSHRLSIQQLGLVLVALLFSYASVASSTLETVKKRGYIKCGVSTGLLGFSEPNQKGIWHGFDVEFCRAVAAAVLKDKGQVKFIPLTAKERFFALQNNDVDLLARNTSWTLHRDTSLNVLFTGVSYYDGQGFLVKTSANINKITELSNPRICFQTGTTTELNLSEYFAQIKQPFQSIPFDAKPQLVTAFEDDRCDVISSDKAGLYSIKQSLKDPLSAHILVSVISKEPLGPVVRDNDSQWFNIVKWTLFTLLNAEENRISSENIDDLKDSSIPHIARFLSTKDNLSEGLQLPLDWRYQIIKQVGNYGQIYERTLGHSSKLKMERGLNALWIDGGIQYAPPIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYA6</accession>
    <name>D0YYA6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CBAH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_002269</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C59 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299764.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002269"/>
    <dbReference type="EnsemblBacteria" id="EEZ41237">
        <property type="protein sequence ID" value="EEZ41237"/>
        <property type="gene ID" value="VDA_002269"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3049">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2047603at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029132">
        <property type="entry name" value="CBAH/NAAA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02275">
        <property type="entry name" value="CBAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBAH" evidence="3">
        <location>
            <begin position="2"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="370" mass="41316" checksum="010B58B2D0DA2073" modified="2010-01-19" version="1">MCTQISIKTLQNDIITGRTNEFGQYYRNNVSFFPRNYDVPNFAIGKSTKLRKAKYAVIGCNIGELFGEAASGLEFLSDGFNEEGLSVGVLYYPNMATYEVVTKASEEMIDVLATPYLILSHCKTVAEAREYVEAHQGKFVVLAGADQPGHFLFIDRTGDAAVFEPDQKGRIEIKPSNGIMTNSPQYEWHLKNLGVYSNIQQFDTADSVLRNLDGSSAHSLAIEVLHHGLAYIDDNLRQGVLVYIESERVNYDIPRVNLLTLEGLSSAYPFVRMTSRVAIDFFGMTEPEKTNVDHLLPIEIQVCTSSADSVTGYQWQTVARFHEAHIFEAMDKLIDCLASPQYFEQCEECKMVSPVGFAACSCQQHLIHAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYF8</accession>
    <name>D0YYF8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulatory protein UhpA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_002321</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299862.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002321"/>
    <dbReference type="EnsemblBacteria" id="EEZ41289">
        <property type="protein sequence ID" value="EEZ41289"/>
        <property type="gene ID" value="VDA_002321"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="3"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="136"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="202" mass="21790" checksum="34067C27BAA46C62" modified="2010-01-19" version="1">MIKVVLIDDHMIVRSGFSQLLSLEEDIEVVGEFGSAAEARVGLPGTEANVCILDISMPDESGLSLLKDIPSGIACIMLSVHDSVAVIEQALSCGAVGYLSKRCSPDELIDAVRSVATGKQYFSPDIEINLVQQEDDEQASVHLTKREREIGLLLAKGLDVKTVAAELGLSHKTVHVHRANAMEKLGVKNNVELAQYFHGDLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYJ9</accession>
    <name>D0YYJ9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cytochrome c-type protein TorY</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_002362</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="7">Binds 5 heme groups per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TorC/TorY family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002362"/>
    <dbReference type="EnsemblBacteria" id="EEZ41330">
        <property type="protein sequence ID" value="EEZ41330"/>
        <property type="gene ID" value="VDA_002362"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3005">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009276">
        <property type="term" value="C:Gram-negative-bacterium-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3820.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009154">
        <property type="entry name" value="Membr-bd_4haem_cyt_TorC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036280">
        <property type="entry name" value="Multihaem_cyt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005126">
        <property type="entry name" value="NapC/NirT_cyt_c_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038266">
        <property type="entry name" value="NapC/NirT_cytc_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03264">
        <property type="entry name" value="Cytochrom_NNT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000014">
        <property type="entry name" value="4_hem_cytch_TorC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48695">
        <property type="entry name" value="SSF48695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02162">
        <property type="entry name" value="torC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0349">Heme</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Cytochrom_NNT" evidence="9">
        <location>
            <begin position="2"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="binding site" description="covalent" evidence="7">
        <location>
            <position position="3"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="4"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="7">
        <location>
            <position position="28"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="7">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="7">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="7">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
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        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>3</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="7">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>4</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="7">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>4</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>4</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="7">
        <location>
            <position position="286"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>5</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="7">
        <location>
            <position position="289"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>5</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="290"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>5</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000014-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000014-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ41330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="340" mass="38353" checksum="75BAD5BFD2B49F5D" modified="2010-01-19" version="1">MGCHAENVAPEFANTIHDKNRSGVRATCPDCHVPHEWTAKISRKIQASKEVFAHFAGFIDTPEKFEDRRLVLAQHEWERFSANGSLECRNCHDYDGMDFSKMSPTARVQMKNAAERDQSCVDCHKGIAHHLPKNMDSSGGLISELVNLSHNTKYADGETVYSVRYLPVYEDKDLKVEAGLLNPASGVKVIAQTDKAIEVEIAGWRKDKGYGRVIQEDFGMNIPVASLVKESAQNDQVVDKYEEKVDDLTGLPWQRVTAKVWMPKDSLVNDITPVWEKAKSAYTTNCSVCHTQPAENHFDANTWPGMFDGMLAFVNFDRDSEALVRKYLQKHSSDFSDEKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYM0</accession>
    <name>D0YYM0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative hydroxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002383</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299996.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002383"/>
    <dbReference type="EnsemblBacteria" id="EEZ41351">
        <property type="protein sequence ID" value="EEZ41351"/>
        <property type="gene ID" value="VDA_002383"/>
    </dbReference>
    <dbReference type="GeneID" id="57341416"/>
    <dbReference type="eggNOG" id="COG4445">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1900811at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045301">
        <property type="term" value="F:tRNA-(2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine)-hydroxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07910">
        <property type="entry name" value="MiaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010386">
        <property type="entry name" value="tRNA-Hydrxlase_MiaE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42637">
        <property type="entry name" value="PTHR42637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06175">
        <property type="entry name" value="MiaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF020736">
        <property type="entry name" value="MiaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="261" mass="30155" checksum="D919FD55C3BA5D5F" modified="2010-01-19" version="1">MTVDTATQTMMDELLTPVKQFLQCETPDEWIAEALKPENLVTLLVDHCNCELKASQTAIYMTRKYAVDEQSATALLEWAKPYENFVYSQNHDIAGFHSKKNALSTKLTPRADFEFGEELIDKMVRLIKEEFHHFEQVLEIMHKRDIPYCHIGAGRYAKGLMKVVRTYEPATLIDKLIIGAYIEARSCERFAKLAPYLDEDLKKFYISLLRSEARHYRDYLTLAEKIAGKDISDRILVIGAREAEMIMSPDHEFRFHSGIPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYQ6</accession>
    <name>D0YYQ6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002419</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300056.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41387">
        <property type="protein sequence ID" value="EEZ41387"/>
        <property type="gene ID" value="VDA_002419"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502ZA91">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1036488at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="290" mass="32788" checksum="D39BE02D674E3713" modified="2010-01-19" version="1">MEQYNLQLSSVKHTAPDGIEMGVMNNGTPYLGARGLAALCGVAPSVIITLVKDWEADLRFKPRGQAIEQLILDQGGDPSSLYVPITVDGKTYHAINDVNCMAILEYYAFESQTPQEQATRNYRSLAKLTLRTFIYERTGYNPEDSLPQYWKTFHERITLNELPSGYFSAFSEIANLVISGIRGGMPFDSNTMPDISVGMAWGKHWCGNSFDEKYGLRRKHLHVFPEDFPQKDPMAWIYPVEALGEFRRWMDDIYVTEKFGTYLNNKAKKGGLNNVDIQALVQAVQPARLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYW7</accession>
    <name>D0YYW7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">Cell division topological specificity factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">minE</name>
        <name evidence="5" type="ORF">VDA_002480</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 4">Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the MinE family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300172.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002480"/>
    <dbReference type="EnsemblBacteria" id="EEZ41448">
        <property type="protein sequence ID" value="EEZ41448"/>
        <property type="gene ID" value="VDA_002480"/>
    </dbReference>
    <dbReference type="GeneID" id="57341298"/>
    <dbReference type="eggNOG" id="COG0851">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2038628at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032955">
        <property type="term" value="P:regulation of division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1070.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00262">
        <property type="entry name" value="MinE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005527">
        <property type="entry name" value="MinE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036707">
        <property type="entry name" value="MinE_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03776">
        <property type="entry name" value="MinE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55229">
        <property type="entry name" value="SSF55229"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01215">
        <property type="entry name" value="minE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4 5" id="KW-0132">Cell division</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="87" mass="9835" checksum="F95ADD89208FFCDA" modified="2010-01-19" version="1">MALLEFFRPKKTTTASVAKERLQIIVAERRSAGQGAPSYLPQLKQDILEVIRKYVAIDPEQVVVTLDQKEEDLAVLELNVTLPEEDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYX7</accession>
    <name>D0YYX7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002490</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300192.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002490"/>
    <dbReference type="EnsemblBacteria" id="EEZ41458">
        <property type="protein sequence ID" value="EEZ41458"/>
        <property type="gene ID" value="VDA_002490"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3803">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1603769at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010323">
        <property type="entry name" value="DUF924"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06041">
        <property type="entry name" value="DUF924"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="201" mass="23378" checksum="A24EEE0FC0F24993" modified="2010-01-19" version="1">MIPEYKQVLDFWFGPLTEEVTVSDRKALWFTGGEEVDRLITMQFHSLVQQAGAGQLSHWTQTPKGTLALIILLDQFSRNIYRGLSAAFRYDSLALAICRRGMSQNQDEELTPIERVFFYLPLEHSEALEDQEESVFRFDRLRNMVSAKNKPVFDGFYRYAVNHHEVIKLFGRYPHRNAAMERLSTPEELAWLNQGGQRFGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYY3</accession>
    <name>D0YYY3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Zinc ABC transporter ATP-binding protein ZnuC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_002496</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300201.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002496"/>
    <dbReference type="EnsemblBacteria" id="EEZ41464">
        <property type="protein sequence ID" value="EEZ41464"/>
        <property type="gene ID" value="VDA_002496"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1121">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1721927at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015633">
        <property type="term" value="F:ABC-type zinc transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017882">
        <property type="entry name" value="ZnuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42734:SF9">
        <property type="entry name" value="PTHR42734:SF9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0406">Ion transport</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0864">Zinc transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="5"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="37"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ41464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="249" mass="27572" checksum="350B33A3AF03B347" modified="2010-01-19" version="1">MTTLVELQSVIVAIQERNVLDNISLKIERGQITTLIGPNGAGKSTLVKIITGLRKPTSGKVIRKKGIKIGYVPQKLRLNDSLPLSVDRFMRLAGKYTAEQRIDSLAQVGGQHLIHNDMHNLSGGEMQRVLLARAILLNPDLLVLDEPVQGVDVNGQIEMYRLIQELRDVLNCAILMVSHDLHLVMAKTDQVICLQHHICCSGTPDAVTAHPSYIALFGDQVAVYKHQHNHEHDLNGQTVSSCCNNHKHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYY8</accession>
    <name>D0YYY8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Oxoglutarate dehydrogenase (succinyl-transferring)</fullName>
            <ecNumber evidence="4">1.2.4.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_002501</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the alpha-ketoglutarate dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.4.2" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300208.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002501"/>
    <dbReference type="EnsemblBacteria" id="EEZ41469">
        <property type="protein sequence ID" value="EEZ41469"/>
        <property type="gene ID" value="VDA_002501"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0567">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="29166at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004591">
        <property type="term" value="F:oxoglutarate dehydrogenase (succinyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11610">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032106">
        <property type="entry name" value="2-oxogl_dehyd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011603">
        <property type="entry name" value="2oxoglutarate_DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031717">
        <property type="entry name" value="KGD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042179">
        <property type="entry name" value="KGD_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23152">
        <property type="entry name" value="PTHR23152"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16078">
        <property type="entry name" value="2-oxogl_dehyd_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16870">
        <property type="entry name" value="OxoGdeHyase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000157">
        <property type="entry name" value="Oxoglu_dh_E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00239">
        <property type="entry name" value="2oxo_dh_E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="Transket_pyr" evidence="7">
        <location>
            <begin position="594"/>
            <end position="787"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ41469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="940" mass="106225" checksum="BA10DD98AF4A35F2" modified="2010-01-19" version="1">MQNGVMKAWLESSHLAGANAAYVEDLYELYLSDPELVDEQWRNVFDALPVVNQTTVEQPHSRVRDYFRRLAKETTFLSTTVTDPDEDAKQVKVLQLINAYRFRGHQHANLDPLGLWQQERVPDLAPEFHNLTEEDFDQSFNVGSFAVGQETMKLSEIYEALKQTYCGSIGAEYMHITDTEEKRWIQQRLESVLGHDEFSQDEQKCFLEELTAAEGLERYLGAKFPGAKRFSLEGGDALIPMVKELIRHAGSQGVREVVVGMAHRGRLNMLVNVLGKKPQDLFDEFAGKHGESWGTGDVKYHQGFSADFATPGGDVHLALAFNPSHLEIVNPVVVGSVRARQDRLGDHQGSKVLPITIHGDSAIAGQGVVAETFNMSQARGYRVGGTVRIVVNNQIGFTTSNPHDTRSTEYCTDIAKMVQAPIFHVNADDPEAVAFVTRLAFDFRHEFKRDVVIDLVCYRRHGHNEADEPNATQPLMYQKIKKHPTPRKLYADYLTEQGVFGLDTATELVNEYRDALDRGECVVKEWRPMKLQSVDWAPYLGHDWTTEWNSKVDIKRLTDLGTRLCQYPESHKLHSRVDKLYNDRLAMIAGEKAVDWGMAETLAYATLVDDGRRVRITGQDSGRGTFFHRHSVLHNQNDASIYVPLAHLHDKQGAFEVFDSVLSEESVLAFEYGYATTEPRGLTIWEAQFGDFANGAQVVIDQFISSGEQKWGRMCGLTMLLPHGYEGQGPEHSSARLERYLQLCAEQNMQVMVPSTPAQVYHMLRQQVLRPMRRPLIVMSPKSLLRHPLCISTMDELANGTFQAAIDEVDALDPTQVKRVVFCSGKVYYDLLEQRRKNEQTDVAIIRIEQLYPFPLELVRELLAPYAHVTDYVWCQEEPQNQGAWYCSQHNFYAAIPAGAKLTYAGRPASASPAVGYMSVHLKQQKALVEDALTVEQKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ50</accession>
    <name>D0YZ50_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protease 3</fullName>
            <ecNumber evidence="4">3.4.24.55</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Pitrilysin</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Protease III</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Protease pi</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">VDA_002563</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Endopeptidase that degrades small peptides of less than 7 kDa, such as glucagon and insulin.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the peptidase M16 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.55" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300337.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002563"/>
    <dbReference type="MEROPS" id="M16.008"/>
    <dbReference type="EnsemblBacteria" id="EEZ41531">
        <property type="protein sequence ID" value="EEZ41531"/>
        <property type="gene ID" value="VDA_002563"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1025">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1188251at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001431">
        <property type="entry name" value="Pept_M16_Zn_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032632">
        <property type="entry name" value="Peptidase_M16_M"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16187">
        <property type="entry name" value="Peptidase_M16_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="SSF63411"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00143">
        <property type="entry name" value="INSULINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase_M16" evidence="14">
        <location>
            <begin position="21"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16_C" evidence="15">
        <location>
            <begin position="180"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16_M" evidence="16">
        <location>
            <begin position="366"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16_C" evidence="15">
        <location>
            <begin position="648"/>
            <end position="826"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00033450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF16187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EEZ41531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="921" mass="105995" checksum="47503DB719053A64" modified="2010-01-19" version="1">MHISPNDHKQYRYLTLDNELKVLLVHDAEAPRSAAALSVQIGHFDDPMDRQGMAHFLEHMLFLGTEKYPKVGEFQTFINQHGGSNNAWTGTENTTFFFEVSPHGFEQGLDRFGQFFTAPLFNADAVDKERNAVDSEYKLKIKDDIRRIYQVHKETINPEHPFSKFSVGDLTTLEDRPNHLVRDDLLAFYHQHYSANIMGLVLLGPQSLDQLEAYTQDFFSQIPNSGKEKAPITAPWVTEAQNQHYIQIEPIKEVRRLSLSFAMPSWDHYYAIKPLSYLAHLLGNEGEGSLMSYLKEKEWINSLAAGGGVNGTNFREFTVSVNLTPQGIEHQDEIVQTIFQYIELIKQRGLNNWRYEEKKSVLEFAFRYQEKSRPLDTVSYLVMNLLHYAPEDIIYGDYMMAGFDEDLIRQVLDYLSPDNMRLILVAQDQHYDQQAQWYDTPYSVTPFTQQQQELWQTKELNKQLMLPEPNPYLCERFDPLPLQEGSELPPQLIQELPGFRLWFKQEHDFRVPKGVVYVAIDSPHAVSSPRNIVKTRLCVEMLLEAINESAYPAEIAGMSYNLYAHQGGVTLQLSGFSEKQPLLLNLILERFKNRQFKPERFDNIKALLLRNWRNAAEDKPISQLFNQLTGLLQPNNPPYPVLIEALESITIDELPGFVDDMFAELHIDTFVYGNWHKDQALALAETLKDAFRVTDQLYGEAQRPLVHLDDCGTLTYELECDHADSAILMYYQSRETSPHKIALYTLANHLMSTTFFHELRTKQQLGYMVGTANLPLNRHPGLILYVQSPVADPVHLAEAIDDFTNAFALVLLELNEAQWQASKQGLIAQISEPDTNLRSRAQRFWVAIGNKDEDFNQRQRVVKAISELSRADMIRFIVDRIKPRTAHRLVMFSQGNQHHEADKLDLGEPITSISQLQEKAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZG9</accession>
    <name>D0YZG9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transcriptional repressor NrdR</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">nrdR</name>
        <name evidence="11" type="ORF">VDA_002682</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8">Binds 1 zinc ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the NrdR family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300690.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002682"/>
    <dbReference type="EnsemblBacteria" id="EEZ41650">
        <property type="protein sequence ID" value="EEZ41650"/>
        <property type="gene ID" value="VDA_002682"/>
    </dbReference>
    <dbReference type="GeneID" id="57341049"/>
    <dbReference type="eggNOG" id="COG1327">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1551627at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00440">
        <property type="entry name" value="NrdR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005144">
        <property type="entry name" value="ATP-cone_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003796">
        <property type="entry name" value="RNR_NrdR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30455">
        <property type="entry name" value="PTHR30455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03477">
        <property type="entry name" value="ATP-cone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00244">
        <property type="entry name" value="TIGR00244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51161">
        <property type="entry name" value="ATP_CONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 8" id="KW-0678">Repressor</keyword>
    <keyword evidence="7 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 8" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="ATP-cone" evidence="10">
        <location>
            <begin position="49"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="zinc finger region" evidence="8">
        <location>
            <begin position="3"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ41650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="149" mass="17069" checksum="2891E0D54BD37C62" modified="2010-01-19" version="1">MHCPFCGANDTKVIDSRLVADGHQVRRRRQCLACNERYTTFETAELVMPRVIKSNGNREPFNEDKLSGGIQRALEKRPVSTDDIERATNNIKSKLRATGEREVTSEMIGNLVMEALKELDKVAYIRFASVYRSFEDIREFGEEIAKLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZK1</accession>
    <name>D0YZK1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH-type transcriptional regulator IscR</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">iscR</name>
        <name evidence="2" type="ORF">VDA_002714</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="1">Binds 1 [2Fe-2S] cluster.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300793.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002714"/>
    <dbReference type="EnsemblBacteria" id="EEZ41682">
        <property type="protein sequence ID" value="EEZ41682"/>
        <property type="gene ID" value="VDA_002714"/>
    </dbReference>
    <dbReference type="GeneID" id="57341014"/>
    <dbReference type="eggNOG" id="COG1959">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1794390at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01176">
        <property type="entry name" value="HTH_type_IscR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010242">
        <property type="entry name" value="TF_HTH_IscR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030489">
        <property type="entry name" value="TR_Rrf2-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000944">
        <property type="entry name" value="Tscrpt_reg_Rrf2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33221">
        <property type="entry name" value="PTHR33221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02082">
        <property type="entry name" value="Rrf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02010">
        <property type="entry name" value="IscR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00738">
        <property type="entry name" value="rrf2_super"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01332">
        <property type="entry name" value="HTH_RRF2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51197">
        <property type="entry name" value="HTH_RRF2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="1" id="KW-0010">Activator</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0678">Repressor</keyword>
    <keyword evidence="1" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="173" mass="18532" checksum="B7D52660EC80854B" modified="2010-01-19" version="1">MRLTSKGRYAVTAMLDVALHSQDGPVPLADISERQGISLSYLEQLFSRLRKAGLVASVRGPGGGYRLGDDANKIAVGMVIAAVDESVDATKCQGKGDCQGGARCLTHTLWRDLSSRISGFLNNITLGELMEDNDVQAISDRQDQELIALGQKTSFGHKKTHDSATTIGVDVRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZN5</accession>
    <name>D0YZN5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Sulfur carrier protein FdhD</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">fdhD</name>
        <name evidence="4" type="ORF">VDA_002748</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FdhD family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300899.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002748"/>
    <dbReference type="EnsemblBacteria" id="EEZ41716">
        <property type="protein sequence ID" value="EEZ41716"/>
        <property type="gene ID" value="VDA_002748"/>
    </dbReference>
    <dbReference type="GeneID" id="57340976"/>
    <dbReference type="eggNOG" id="COG1526">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="948173at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097163">
        <property type="term" value="F:sulfur carrier activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016783">
        <property type="term" value="F:sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00187">
        <property type="entry name" value="FdhD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003786">
        <property type="entry name" value="FdhD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30592">
        <property type="entry name" value="PTHR30592"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02634">
        <property type="entry name" value="FdhD-NarQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015626">
        <property type="entry name" value="FdhD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00129">
        <property type="entry name" value="fdhD_narQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Mo-bisPGD binding" evidence="3">
        <location>
            <begin position="258"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine persulfide intermediate" evidence="3">
        <location>
            <position position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="282" mass="31224" checksum="82B69FA3C588C80C" modified="2010-01-19" version="1">MTSCPIDTEYFKHAEYSTHEIIKYENGIKTECEDYIAEEVPVALIYNGISHVVMMTTPSNLESFAIGFSLSERIISDIKEIKYIDIKSNYQGIEVHIELQMRPFMLLKEQRRQLVGRTGCGLCGIEHLKQAMKPVSPVNNDEVIHLSVLNQCLDKLYQQQELAGTTGCTHAAVWVDSCGNLAAIYEDVGRHVAMDKLIGARAKSSLLTHGAVLITSRASYEIVQKATSVGIEILMAVSAPTALAIKLAEDSGLTLVGFCRKGRATIYTHPHRVITDNNIRSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZT1</accession>
    <name>D0YZT1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Arginine/agmatine antiporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_002794</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301026.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002794"/>
    <dbReference type="EnsemblBacteria" id="EEZ41762">
        <property type="protein sequence ID" value="EEZ41762"/>
        <property type="gene ID" value="VDA_002794"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0531">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="527053at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027562">
        <property type="entry name" value="His_histam_anti"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04298">
        <property type="entry name" value="his_histam_anti"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="45"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="93"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="195"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="229"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="279"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="329"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="354"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="389"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="415"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="448" mass="47248" checksum="06033186CE650600" modified="2010-01-19" version="1">MSDMSISQAHKIGVLALTLVTASNMMGSGVFMLPTNLAGIGTISIYGWIFTIVGVLALALVFAKTSLINPKDGGIVAYANDAFGPFIGFQSTICYWISAWIGNVALLVAGVGYLSFFFPILKDPTYGSITAICILWAFVILASFGANVATKAQSFTAICGLIVILGVGLIGWGWFNPQTYNAVYNGTGQSNMHAIISAASIALWGFLGVESAVVASGQVKDPEKTVPKATVYGLLITSVCYVGSCAVIMGIVPHDVLIHSPAPFADAAKYMFGPTAGNIASALSIIACFGSISGWLILQSEAPKAGAKSGLFPKFFGEVNKNNVPMKSLIFTGVLMSIVLLMTASPNLADQFQIIILMSVFASLLPYMYAIIALPIIMAAKKMDKGRKFYTYAILTAIGMIYSIFALLGSGSDSIFWGVVMLICTIPLYSFVAAKKAHSGKSVIDAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZV5</accession>
    <name>D0YZV5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Membrane fusion protein (MFP) family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">VDA_002818</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell inner membrane</location>
            <topology evidence="8">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301095.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002818"/>
    <dbReference type="EnsemblBacteria" id="EEZ41786">
        <property type="protein sequence ID" value="EEZ41786"/>
        <property type="gene ID" value="VDA_002818"/>
    </dbReference>
    <dbReference type="GeneID" id="57340902"/>
    <dbReference type="eggNOG" id="COG0845">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1395473at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039562">
        <property type="entry name" value="MFP_biotin_lipoyl_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006144">
        <property type="entry name" value="Secretion_HlyD_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010129">
        <property type="entry name" value="T1SS_HlyD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13533">
        <property type="entry name" value="Biotin_lipoyl_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01843">
        <property type="entry name" value="type_I_hlyD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00543">
        <property type="entry name" value="HLYD_FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="domain" description="Biotin_lipoyl_2" evidence="10">
        <location>
            <begin position="65"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="107"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="278"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU365093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ41786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="460" mass="51572" checksum="9168C902D29D5677" modified="2010-01-19" version="1">MKQSSSLDELDMTDDLYKAMLLDSPKQHRWVIRLFFIMVICFISWAAWAQLDQVTRGEGKVIPSSQVQMIQSLDGGILQELFVTEGMQVTKGQPLARIDDTRFRSDLAQQVEEEESLQANIFRLKQEIQSIEIADANKGWKEQVRVNKAPLDFPKALVANEPELIKQQTAEYHGRLDELNNQIAILARQIVQKQQESHGLVSQIKTLKSSLHLINKELVMTRPLARKGIVSEVDLLQLQRQVNETKGELSTLYLQQPKVKAALDEAILKRREAVLTYNKEARAQLNELSARLSRLTEAQVGAQDKVDKAIITSPVNGTIKMINIMTLGGVVQPGKDIMEIVPSEDQLLIEVKIAPKDIAFLHPGLPAVVKVTAYDFTRYGGLDGTVVTISADTTQDKDDNSFYLIKVRTKESSLARSDGTLMPIIPGMLTSVDVITGKRSVLDYILNPILRAKEMALREH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZV9</accession>
    <name>D0YZV9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">[Ribosomal protein S18]-alanine N-acetyltransferase</fullName>
            <ecNumber evidence="5 6">2.3.1.266</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rimI</name>
        <name evidence="8" type="ORF">VDA_002822</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Acetylates the N-terminal alanine of ribosomal protein S18.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>acetyl-CoA + N-terminal L-alanyl-[ribosomal protein bS18] = CoA + H(+) + N-terminal N(alpha)-acetyl-L-alanyl-[ribosomal protein bS18]</text>
            <dbReference type="Rhea" id="RHEA:43756"/>
            <dbReference type="Rhea" id="RHEA-COMP:10676"/>
            <dbReference type="Rhea" id="RHEA-COMP:10677"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:64718"/>
            <dbReference type="ChEBI" id="CHEBI:83683"/>
            <dbReference type="EC" id="2.3.1.266"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the acetyltransferase family. RimI subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.266" evidence="5 6"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301109.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002822"/>
    <dbReference type="EnsemblBacteria" id="EEZ41790">
        <property type="protein sequence ID" value="EEZ41790"/>
        <property type="gene ID" value="VDA_002822"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1826274at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008999">
        <property type="term" value="F:ribosomal protein S5-alanine N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017189">
        <property type="term" value="P:N-terminal peptidyl-alanine acetylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02210">
        <property type="entry name" value="RimI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006464">
        <property type="entry name" value="AcTrfase_RimI/Ard1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043690">
        <property type="entry name" value="RimI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01575">
        <property type="entry name" value="rimI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2 5 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="7">
        <location>
            <begin position="3"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Acetyl-CoA binding" evidence="5">
        <location>
            <begin position="70"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Acetyl-CoA binding" evidence="5">
        <location>
            <begin position="78"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="104"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="116"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ41790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="148" mass="17022" checksum="69EF8C7FBCBDB9BC" modified="2010-01-19" version="1">MTHKIIPLQAQHLDDVWRIEQAAHAFPWAESIVRKEPNKIAANYALLVDDKLVGYCFGQLVAGEGTLLNIAIDPNEQRKGYGRILLEGFIEQLEAKQAEEIWLEVRESNVSAYKLYEDVGFNEINRRVGYYPSQDGREDALIMTYMFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z004</accession>
    <name>D0Z004_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Thiol:disulfide interchange protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">VDA_002867</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the thioredoxin family. DsbC subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301241.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002867"/>
    <dbReference type="EnsemblBacteria" id="EEZ41835">
        <property type="protein sequence ID" value="EEZ41835"/>
        <property type="gene ID" value="VDA_002867"/>
    </dbReference>
    <dbReference type="GeneID" id="57340843"/>
    <dbReference type="eggNOG" id="COG1651">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1678187at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03020">
        <property type="entry name" value="DsbA_DsbC_DsbG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033954">
        <property type="entry name" value="DiS-bond_Isoase_DsbC/G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018950">
        <property type="entry name" value="DiS-bond_isomerase_DsbC/G_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009094">
        <property type="entry name" value="DiS-bond_isomerase_DsbC/G_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10411">
        <property type="entry name" value="DsbC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13098">
        <property type="entry name" value="Thioredoxin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54423">
        <property type="entry name" value="SSF54423"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 9" id="KW-0574">Periplasm</keyword>
    <keyword evidence="8 9" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5010003576" description="Thiol:disulfide interchange protein" evidence="9">
        <location>
            <begin position="23"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="DsbC_N" evidence="10">
        <location>
            <begin position="34"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin-like_fold" evidence="11">
        <location>
            <begin position="111"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF10411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF13098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ41835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="243" mass="26386" checksum="5CCD8115CE7234C1" modified="2010-01-19" version="1">MHIIGRTLLATVIAATAFSASAAPNKAAITKKLSAIGLVPTEITASQVAGLNEVVTERGIVYTSDDGNYFIVGHLYDNQAAQPVNVTEQKMAKINKDKLQGMEDEMIIYPAKNQKHVITVFTDTTCGYCRKLHNEMQAYNDKGITVRYLAFPRGGEQSGNFMQMAQIWGAKDRAKAMDDAKNGSFDPKGITPRTDLIKKHYELGVAMGVNGTPAIVLEDGTMIPGYQPAASLSQMLDAQQSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z020</accession>
    <name>D0Z020_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Isocitrate dehydrogenase kinase/phosphatase</fullName>
            <shortName evidence="4">IDH kinase/phosphatase</shortName>
            <shortName evidence="4">IDHK/P</shortName>
            <ecNumber evidence="4">2.7.11.5</ecNumber>
            <ecNumber evidence="4">3.1.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">aceK</name>
        <name evidence="5" type="ORF">VDA_002883</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>ATP + L-seryl-[isocitrate dehydrogenase] = ADP + H(+) + O-phospho-L-seryl-[isocitrate dehydrogenase]</text>
            <dbReference type="Rhea" id="RHEA:43540"/>
            <dbReference type="Rhea" id="RHEA-COMP:10605"/>
            <dbReference type="Rhea" id="RHEA-COMP:10606"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.5"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the AceK family.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.5" evidence="4"/>
    <dbReference type="EC" id="3.1.3.-" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301269.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002883"/>
    <dbReference type="EnsemblBacteria" id="EEZ41851">
        <property type="protein sequence ID" value="EEZ41851"/>
        <property type="gene ID" value="VDA_002883"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4579">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="245269at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008772">
        <property type="term" value="F:[isocitrate dehydrogenase (NADP+)] kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004721">
        <property type="term" value="F:phosphoprotein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006097">
        <property type="term" value="P:glyoxylate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00747">
        <property type="entry name" value="AceK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010452">
        <property type="entry name" value="Isocitrate_DH_AceK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39559">
        <property type="entry name" value="PTHR39559"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06315">
        <property type="entry name" value="AceK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000719">
        <property type="entry name" value="AceK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 4" id="KW-0329">Glyoxylate bypass</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4 5" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="active site" evidence="4">
        <location>
            <position position="371"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="315"/>
            <end position="321"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="336"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="574" mass="67079" checksum="925103843D7B9620" modified="2010-01-19" version="1">MAAKMDLLAAQTILQGFDAMYGRFLDVTAGAQARFEQQLWPDVHHALKARIHFYDHHVGLVTHQIQAMVGERYNNQNFITQVKAAYEDLLIDYPRYDIAESFFNSVYCRIFQHKHIAPDKLFVDSSQQQRIPIYPTNLTRIYHYQDSLEQLLQRLLNDTPFTLSWRDQTNDITLLIEHLQQEFGERLTLLSHIELIREPFYRNKAAYLVGQLQFSDHTTSPIVLPILNHHGQSLYIDACICDVNDVSIIFGFARSYFMVYAPAPAALVRFLAQLMPNKTLAELYTAIGCQKHAKTELYRDFIHHLAQSNDQFILAPGVKGMVMSVFTLPSYDFVFKIIKDTFAPQKDIRHNTVKEKYLLVKEHDRVGRMADTQEYRNFSFPKHRFSDELLEELQEVAPSIVHICDDEILIDHLYMERRMVPLNLYIETATEVDIYHAINEYGTAIKQLAAANIFPGDMLFKNFGVTRHKRVVFYDYDEISYMTEVNFRRIPPPRYPEDELAAEPWYSVGPNDVFPEEFPTFLVPNPQVRKLFELLHGDLFEASFWQQLQQNIKQGKLEDVYPYQNHHKLLPKLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z027</accession>
    <name>D0Z027_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Glutamate synthase [NADPH] large chain</fullName>
            <ecNumber evidence="16">1.4.1.13</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">VDA_002890</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="14">Amino-acid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glutamate synthase family.</text>
    </comment>
    <dbReference type="EC" id="1.4.1.13" evidence="16"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301280.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002890"/>
    <dbReference type="EnsemblBacteria" id="EEZ41858">
        <property type="protein sequence ID" value="EEZ41858"/>
        <property type="gene ID" value="VDA_002890"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0067">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0069">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5568at2"/>
    <dbReference type="UniPathway" id="UPA00088">
        <property type="reaction ID" value="UER00178"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051538">
        <property type="term" value="F:3 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004355">
        <property type="term" value="F:glutamate synthase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006537">
        <property type="term" value="P:glutamate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00982">
        <property type="entry name" value="gltB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02808">
        <property type="entry name" value="GltS_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002489">
        <property type="entry name" value="Glu_synth_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036485">
        <property type="entry name" value="Glu_synth_asu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006982">
        <property type="entry name" value="Glu_synth_centr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002932">
        <property type="entry name" value="Glu_synthdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00310">
        <property type="entry name" value="GATase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04898">
        <property type="entry name" value="Glu_syn_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01645">
        <property type="entry name" value="Glu_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01493">
        <property type="entry name" value="GXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69336">
        <property type="entry name" value="SSF69336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0003">3Fe-4S</keyword>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0288">FMN</keyword>
    <keyword evidence="12" id="KW-0314">Glutamate biosynthesis</keyword>
    <keyword evidence="8" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 16" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="15">
        <location>
            <begin position="12"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00029440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EEZ41858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="1486" mass="163416" checksum="5CBC5739E51045E0" modified="2010-01-19" version="1">MLYDSSLEKDNCGFGLIAHTQGEPSHKLVRTAITALDRMTHRGGIAADGKTGDGCGLLMKKPDSFYRHIAEELQWHLAREYAVGMIFFNQDPTRANQAKQIIEAELKKETLSIVGWRKVPIDPTVLGPIAQDSLPTIEQIFVNAPAGWKPRDVDRRLYIAKRRIEQQLVDDSEFYICSLSTQVVVYKGLCMPADLPRFYRDLGDIRLESAICLFHQRFSTNTQPRWPLAQPFRYLAHNGEINTIAGNRQWARARGYKFASPLLPDLQSAAPFVNETGSDSSSLDNMLELFLAGGMDLFRAMRMLVPPAWQNHPDMDPKLRAFYDFNSKHMEPWDGPAGIVMSDGRYAACNLDRNGLRPARYVITKDNLITLASEVGIWDYAADEVKQKGRVGPGELLVIDTKFGQIWHSADIDNELMNRHPYQHWMEQHVQHLIPFEQLDDEQVGSRALNNEQLKTYQKLFNISREELEQVLRVMGENGQEATGSMGDDTPMAVLSSQQRPITDYFRQMFAQVTNPPIDPLRENHVMSLATSIGREMNVFCETDGHAARVSFQSPVLLFSDFEQLKQLDPSHYGHSQIELNFDPTKQSLEQAIIHCCDQAQNAIQQGSVLLILSDRNIQPHSYPIPAAMAVGAIQQRLVDTHLRCDANIIVETATARDPHQFAVLLGFGATAVYPYLAYESLAALIDNNTITKSYRQVMLNYRNSINKGLFKIMSKMGISTISSYRCAHLFEAVGLHQNIIKLCFNGVVSRIQGAQFSDFEQDLYNLNRRAWLKRQPLNHGGLLKYVFDGEFHAYNPDVVTLLQQAVKSGQYCDYQAYSQAVNQRPIATLRDLFTLTENTTPIDLAQVEPLDALYPRFDSAAMSIGALSPEAHQALAIAMNRLGGFSNSGEGGEDPSRFHSERNSRIKQVASGRFGVTPHYLVNADVIQIKVAQGAKPGEGGQLPGHKVTTEIAKLRHAVPGVTLISPPPHHDIYSIEDLAQLIFDLKQVNPAALISVKLVSEPGVGTIATGVAKAYADLITISGYDGGTGASPLTSVKYAGSPWELGLVETQQALVSNGLRHKVRVQVDGGLKTGLDVVKAAILGAESFGFGTAPMVALGCKYLRICHLNNCATGVATQDEHLRQKYFKGLPEQVMNYFMGLGHEVRELLAQLGVTKLTDLIGRTDLLTCLPGTTHKQSQLDLSALLISAPIQDGKTPYCSEENQPFDQGKLNQHIVEQTICAVEQKQSLQLHFAIQNTDRAVGARLSGEIAKRYGNGGVATSPITLNFIGSAGQSFGVWNAGGLTLNLIGDANDYVGKGMAGGRIVIAPPQGSAFASHQATIIGNTCLYGATGGELFAAGCAGERFAVRNSGAIAVIEGAGDNACEYMTGGIIAILGSTGVNFGAGMTGGFAYILDEKGDFGGRVNSELIEIIELSQLPIHQEHLRGLIDKHYQQTGSERAQQILSLFDNWIERFYLAKPKSADVSTLLGHQSRSSAELRIQAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z028</accession>
    <name>D0Z028_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glutamate synthase [NADPH] small chain</fullName>
            <ecNumber evidence="4">1.4.1.13</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_002891</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.4.1.13" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301281.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002891"/>
    <dbReference type="EnsemblBacteria" id="EEZ41859">
        <property type="protein sequence ID" value="EEZ41859"/>
        <property type="gene ID" value="VDA_002891"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0493">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="671513at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004355">
        <property type="term" value="F:glutamate synthase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028261">
        <property type="entry name" value="DPD_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006006">
        <property type="entry name" value="GltD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42783:SF1">
        <property type="entry name" value="PTHR42783:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14691">
        <property type="entry name" value="Fer4_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01318">
        <property type="entry name" value="gltD_gamma_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fer4_20" evidence="3">
        <location>
            <begin position="25"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_2" evidence="2">
        <location>
            <begin position="147"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="472" mass="52106" checksum="BB508897B8469EF0" modified="2010-01-19" version="1">MSQNIYQFVDVARIDPTKKPLKIRKIEFVEIYEPFTQLQAKAQADRCLDCGNPYCEWKCPVHNYIPQWLKLANEGKIIEAAELSHQTNSLPEVCGRVCPQDRLCESACTLNDDFGAVTIGNIEKYITDKAFELGWKPDLSHVEWSDKKVAIIGAGPAGLACADILVRNGVKPVVFDKYSEIGGLLTFGIPAFKLEKEIMIHRRQLFSEMGVQFELNTEIGRDIEFSHIMTQFDAVFLAIGTYKNIRANLTNEDADGVLDALPYLIANTEHLLQPSTRQHAKLSMQGKRVVVLGGGDTAMDCVRTAIRQNAHDVVCAYRRDEANMPGSKREVQNAKEEGVRFLFNLQPIAIETNSQGQVSAVTVVSTQLGQPDSAGRRRPEIIAGSEQHLPADAVIMAFGFQPHATPWLDNFAVEKDPQGCIIAPADGDFAYQTTNPKLFAGGDAVRGSDLVVTAIDEGRKAALGILDYLDLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z064</accession>
    <name>D0Z064_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Carbamate kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_002927</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the carbamate kinase family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301372.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002927"/>
    <dbReference type="EnsemblBacteria" id="EEZ41895">
        <property type="protein sequence ID" value="EEZ41895"/>
        <property type="gene ID" value="VDA_002927"/>
    </dbReference>
    <dbReference type="GeneID" id="57340769"/>
    <dbReference type="eggNOG" id="COG0549">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="901370at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008804">
        <property type="term" value="F:carbamate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006525">
        <property type="term" value="P:arginine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04235">
        <property type="entry name" value="AAK_CK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003964">
        <property type="entry name" value="Carb_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30409">
        <property type="entry name" value="PTHR30409"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000723">
        <property type="entry name" value="Carbamate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00746">
        <property type="entry name" value="arcC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AA_kinase" evidence="3">
        <location>
            <begin position="5"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR000723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="303" mass="32553" checksum="BF80F9EE427D4627" modified="2010-01-19" version="1">MAKQTVVVALGGNALLRRGEPLEAEIQRQNIATAAKTIAQIAEEYNVVLVHGNGPQVGLLALQGLEFKKVAPYPLDVLGSETQGMIGYMLMQELKNLLPEQNVSCMLTQMSVDPNDPAFADPTKPIGPVYDEAEAREMAEKYHWTVKPDGQYFRRVVPSPLPTGIIEKDAINTLIENDHLVICTGGGGIPVKHENGQLVGVEAVIDKDMSAAFLAKQLEADALLILTDADAVYLDWGKPTQKALSSTTPSELSQYTFDAGSMGPKIEASCEFIKQGGKLVGIGSLADGLRILKGERGTNIIAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z089</accession>
    <name>D0Z089_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5 6">30S ribosomal protein S21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpsU</name>
        <name evidence="7" type="ORF">VDA_002952</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the bacterial ribosomal protein bS21 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301411.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="SMR" id="D0Z089"/>
    <dbReference type="STRING" id="675817.VDA_002952"/>
    <dbReference type="EnsemblBacteria" id="EEZ41920">
        <property type="protein sequence ID" value="EEZ41920"/>
        <property type="gene ID" value="VDA_002952"/>
    </dbReference>
    <dbReference type="GeneID" id="61231240"/>
    <dbReference type="eggNOG" id="COG0828">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2088764at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00358">
        <property type="entry name" value="Ribosomal_S21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001911">
        <property type="entry name" value="Ribosomal_S21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018278">
        <property type="entry name" value="Ribosomal_S21_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038380">
        <property type="entry name" value="S21_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21109">
        <property type="entry name" value="PTHR21109"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01165">
        <property type="entry name" value="Ribosomal_S21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00976">
        <property type="entry name" value="RIBOSOMALS21"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00030">
        <property type="entry name" value="S21p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01181">
        <property type="entry name" value="RIBOSOMAL_S21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="71" mass="8498" checksum="B2ECA7C1FC128BFC" modified="2010-01-19" version="1">MPVIKVRENEPFDVALRRFKRSCEKAGILSEVRRREHFEKPTTVRKRAKAAAVKRHLKKLARENARRVRLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0N2</accession>
    <name>D0Z0N2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">50S ribosomal protein L11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rplK</name>
        <name evidence="12" type="ORF">VDA_003096</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 9">Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.</text>
    </comment>
    <comment type="PTM">
        <text evidence="7 9">One or more lysine residues are methylated.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the universal ribosomal protein uL11 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301848.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003096"/>
    <dbReference type="EnsemblBacteria" id="EEZ42063">
        <property type="protein sequence ID" value="EEZ42063"/>
        <property type="gene ID" value="VDA_003096"/>
    </dbReference>
    <dbReference type="GeneID" id="57340425"/>
    <dbReference type="eggNOG" id="COG0080">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1702697at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00349">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00736">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000911">
        <property type="entry name" value="Ribosomal_L11/L12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036796">
        <property type="entry name" value="Ribosomal_L11/L12_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006519">
        <property type="entry name" value="Ribosomal_L11_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020783">
        <property type="entry name" value="Ribosomal_L11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036769">
        <property type="entry name" value="Ribosomal_L11_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020785">
        <property type="entry name" value="Ribosomal_L11_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020784">
        <property type="entry name" value="Ribosomal_L11_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11661">
        <property type="entry name" value="PTHR11661"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00298">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03946">
        <property type="entry name" value="Ribosomal_L11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00649">
        <property type="entry name" value="RL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46906">
        <property type="entry name" value="SSF46906"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54747">
        <property type="entry name" value="SSF54747"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01632">
        <property type="entry name" value="L11_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00359">
        <property type="entry name" value="RIBOSOMAL_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7 9" id="KW-0488">Methylation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 7 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 7 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7 9" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L11_N" evidence="11">
        <location>
            <begin position="9"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L11" evidence="10">
        <location>
            <begin position="72"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ42063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="142" mass="14776" checksum="7D576228F0D57082" modified="2010-01-19" version="1">MAKKVEAYIKLQVAAGMANPSPPVGPALGQHGVNIMEFCKAFNAKTDSLEKGLPTPVVITVYSDRSFTFITKTPPAAVLLKKAAGVKSGSGRPNTEKVGTVTEAQIQEIAETKAADMTGADIEAMKRSIAGTARSMGLVVEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0P2</accession>
    <name>D0Z0P2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">Glutamate racemase</fullName>
            <ecNumber evidence="2 7">5.1.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">murI</name>
        <name evidence="8" type="ORF">VDA_003106</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Provides the (R)-glutamate required for cell wall biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>L-glutamate = D-glutamate</text>
            <dbReference type="Rhea" id="RHEA:12813"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:29986"/>
            <dbReference type="EC" id="5.1.1.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the aspartate/glutamate racemases family.</text>
    </comment>
    <dbReference type="EC" id="5.1.1.3" evidence="2 7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301876.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003106"/>
    <dbReference type="EnsemblBacteria" id="EEZ42073">
        <property type="protein sequence ID" value="EEZ42073"/>
        <property type="gene ID" value="VDA_003106"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0796">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1718671at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008881">
        <property type="term" value="F:glutamate racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00258">
        <property type="entry name" value="Glu_racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015942">
        <property type="entry name" value="Asp/Glu/hydantoin_racemase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001920">
        <property type="entry name" value="Asp/Glu_race"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018187">
        <property type="entry name" value="Asp/Glu_racemase_AS_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033134">
        <property type="entry name" value="Asp/Glu_racemase_AS_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004391">
        <property type="entry name" value="Glu_race"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21198:SF2">
        <property type="entry name" value="PTHR21198:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01177">
        <property type="entry name" value="Asp_Glu_race"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53681">
        <property type="entry name" value="SSF53681"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00067">
        <property type="entry name" value="glut_race"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00923">
        <property type="entry name" value="ASP_GLU_RACEMASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00924">
        <property type="entry name" value="ASP_GLU_RACEMASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0133">Cell shape</keyword>
    <keyword evidence="6 7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="5 7 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 7" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="16"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="48"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="81"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="190"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="7">
        <location>
            <position position="80"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="7">
        <location>
            <position position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ42073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="273" mass="29837" checksum="5C2530595C767E60" modified="2010-01-19" version="1">MFIDIWCRVKKVVIFDSGVGGLSVYQEIRARLPQAQYIYAFDNAAFPYGELPQQVLIERACHIITNLVARHQADLVVVACNTASTIVLPALRQQLTIPVVGVVPAIKPAAQASLSKSIGLLATPATVERPYTHDLVKQFAQDCQVLMLGTTRLVEMAEEKLQGEVVSLNELTQILAPWLGKVDTIVLGCTHFPLMRAEIQQVCGAGVTIIDSGKAIANRVVSLLPESATQDAALEEMDNLTYCSAKPTRLDALNKSLQEMKLGAIQCLNYPYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z137</accession>
    <name>D0Z137_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Valine--pyruvate aminotransferase</fullName>
            <ecNumber evidence="2">2.6.1.66</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003251</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.6.1.66" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302290.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003251"/>
    <dbReference type="EnsemblBacteria" id="EEZ42218">
        <property type="protein sequence ID" value="EEZ42218"/>
        <property type="gene ID" value="VDA_003251"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3977">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1024978at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009042">
        <property type="term" value="F:valine-pyruvate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="2" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="1">
        <location>
            <begin position="60"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="416" mass="46658" checksum="33C1DE7B96F668DB" modified="2010-01-19" version="1">MEFSTFGDKFARYSSIAQLMDDLNDGLQDPNAIMLGGGNPAQIPTINAYFTQLLSEMAASSELTQAMSNYDGPQGKNRFLIALAAMLKQQYGWEISERNIVLTNGSQSAFFSLFNLLAGKYQDGSHKKILLPLSPEYIGYSDAGVHDDMFISYRPEITLLDNGLFKYHIDFSTLTITPDIGAICVSRPTNPTGNVLTDEEIAKLDTLAQQHHIPLIIDNAYGMPFPDIIFADVTPFWNPNTILCMSLSKLGLPGVRCGIVIANETIVQALANMNGVLNLAPGSVGPAVAHKLIERNELLSLSHQVIKPFYQRKATQAVSWLQRAIPDPRFRIHKPEGAIFLWLWFDELPITTTELYRRLKQRGVLIVPGEYFFIGLEDSWQHQHQCLRMNYVQDDEVMKQGIDIIAQEVKKAYLEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z157</accession>
    <name>D0Z157_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Phosphomethylpyrimidine synthase</fullName>
            <ecNumber evidence="10">4.1.99.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Hydroxymethylpyrimidine phosphate synthase</fullName>
            <shortName evidence="10">HMP-P synthase</shortName>
            <shortName evidence="10">HMP-phosphate synthase</shortName>
            <shortName evidence="10">HMPP synthase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Thiamine biosynthesis protein ThiC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">thiC</name>
        <name evidence="12" type="ORF">VDA_003271</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + S-adenosyl-L-methionine = 4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + 5'-deoxyadenosine + CO + formate + 3 H(+) + L-methionine</text>
            <dbReference type="Rhea" id="RHEA:24840"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:17245"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58354"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:137981"/>
            <dbReference type="EC" id="4.1.99.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="10">Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="10">Cofactor biosynthesis; thiamine diphosphate biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the ThiC family.</text>
    </comment>
    <dbReference type="EC" id="4.1.99.17" evidence="10"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302347.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003271"/>
    <dbReference type="EnsemblBacteria" id="EEZ42238">
        <property type="protein sequence ID" value="EEZ42238"/>
        <property type="gene ID" value="VDA_003271"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0422">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="505395at2"/>
    <dbReference type="UniPathway" id="UPA00060"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016830">
        <property type="term" value="F:carbon-carbon lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.540">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00089">
        <property type="entry name" value="ThiC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037509">
        <property type="entry name" value="ThiC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025747">
        <property type="entry name" value="ThiC-associated_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038521">
        <property type="entry name" value="ThiC/Bza_core_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002817">
        <property type="entry name" value="ThiC/BzaA/B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30557">
        <property type="entry name" value="PTHR30557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13667">
        <property type="entry name" value="ThiC-associated"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01964">
        <property type="entry name" value="ThiC_Rad_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00407">
        <property type="entry name" value="phosphomethylpyrimidine_syntha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00190">
        <property type="entry name" value="thiC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 10" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7 10" id="KW-0408">Iron</keyword>
    <keyword evidence="8 10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6 10" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="5 10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="ThiC-associated" evidence="11">
        <location>
            <begin position="22"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="350"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="391"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="265"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="294"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="330"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="430"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="434"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="457"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="498"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="578"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="581"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="586"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF13667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ42238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="642" mass="72173" checksum="B00A6AC0E6957695" modified="2010-01-19" version="1">MSNRKQARQHAKHFIDTLSVSPYPNSQKIYVSADHRPDIRVAMREIALADSLIGGSREHPEYQDNQPIRVYDTSGVYTDPNHIIDLYSGLPKLRASWIAERQDCEVLTERSSAFAQQRAEDPLLDDLRFNHTTPIFRAKTNRCVTQLHYARQGVITPEMEYIALRENMGRAQYRDQVLNQQHDGQSFGASLPTEISAEFVRQEVAQGRAIIPANINHPEAEPMIIGRNFLVKVNANIGNSSVTSSIEEEVEKLVWATRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPMYQALEKVNGIAENLTWEIMRDTLIEQAEQGVDYFTIHAGVLLRYVPLTAQRVTGIVSRGGSIIAKWCLAHHQENFLYTHFSEICQICAQYDVSLSLGDGLRPGSVADANDEAQFSELRTLGELTKIAWQYDVQVMVEGPGHVPMQMIKANMDEQLTHCHQAPFYTLGPLTTDIAPGYDHITSGVGAAMIGWYGCAMLCYVTPKEHLGLPNKEDVKTGLITYKLCAHAADLAKGHPGAQIRDNALSKARFEFRWQDQFNLSLDPDTAKAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYASNLTQEQDITVAVLDDPLEGMQQKADEFRARGSELYHPVKKENI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z183</accession>
    <name>D0Z183_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_003297</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302427.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003297"/>
    <dbReference type="EnsemblBacteria" id="EEZ42264">
        <property type="protein sequence ID" value="EEZ42264"/>
        <property type="gene ID" value="VDA_003297"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="990666at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ42264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="282" mass="31754" checksum="C9F19460347F6DF4" modified="2010-01-19" version="1">MDLRLLRFFTAVYEEKNITLAAERCFVSQPSISSAIKQLEQELETTLFIRHKKGVNLTDEAHYLYPLAIRLLNDVNRLPQLFQQRTECLPLTLANFPDLSQTELANCFALLNQQIPNLLLELVDHNAPADARLTLDMFKAEDEIFLPLWDEDYVLCMLPDHPLAQLEKVTPAELHLHDFIECPPCEAHQQTIGLLACDGLAVNLVAKAEHKTQVMHLVQAGLGISFLPTGVLETAKQLVTVPLDGPRMFRRLGLCYPANKTLNPALSAAVKVLSQYNQHKVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1A1</accession>
    <name>D0Z1A1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">LexA repressor</fullName>
            <ecNumber evidence="12">3.4.21.88</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">lexA</name>
        <name evidence="16" type="ORF">VDA_003315</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>Hydrolysis of Ala-|-Gly bond in repressor LexA.</text>
            <dbReference type="EC" id="3.4.21.88"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="12">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 12 13">Belongs to the peptidase S24 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.88" evidence="12"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302475.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003315"/>
    <dbReference type="MEROPS" id="S24.001"/>
    <dbReference type="EnsemblBacteria" id="EEZ42282">
        <property type="protein sequence ID" value="EEZ42282"/>
        <property type="gene ID" value="VDA_003315"/>
    </dbReference>
    <dbReference type="GeneID" id="57340244"/>
    <dbReference type="eggNOG" id="COG1974">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1933795at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06529">
        <property type="entry name" value="S24_LexA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00015">
        <property type="entry name" value="LexA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006200">
        <property type="entry name" value="LexA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039418">
        <property type="entry name" value="LexA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006199">
        <property type="entry name" value="LexA_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006197">
        <property type="entry name" value="Peptidase_S24_LexA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015927">
        <property type="entry name" value="Peptidase_S24_S26A/B/C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01726">
        <property type="entry name" value="LexA_DNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00717">
        <property type="entry name" value="Peptidase_S24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00726">
        <property type="entry name" value="LEXASERPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="SSF51306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00498">
        <property type="entry name" value="lexA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12 13" id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword evidence="4 12" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10 12" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3 12" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 12 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="16" id="KW-0645">Protease</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 12" id="KW-0678">Repressor</keyword>
    <keyword evidence="11 12" id="KW-0742">SOS response</keyword>
    <keyword evidence="9 12" id="KW-0804">Transcription</keyword>
    <keyword evidence="7 12" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="LexA_DNA_bind" evidence="15">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S24" evidence="14">
        <location>
            <begin position="83"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="12">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="active site" description="For autocatalytic cleavage activity" evidence="12">
        <location>
            <position position="125"/>
        </location>
    </feature>
    <feature type="active site" description="For autocatalytic cleavage activity" evidence="12">
        <location>
            <position position="162"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage; by autolysis" evidence="12">
        <location>
            <begin position="90"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF01726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EEZ42282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="208" mass="22878" checksum="9FE6A1416FA016B7" modified="2010-01-19" version="1">MKPLTPRQQEVFDLIKAKIEDSGMPPTRAEIARELGFRSANAAEEHLKALARKGVLEIVPGASRGIRLLVGANDSDVEESGLPLIGQVAAGEPILAQEHVECHYDVDPTLFKPRADFLLRVNGMSMKNIGIMDGDLLAVHKTQDVRNGQVVVARVDDDVTVKRLDKQGRKVLLHAENEEFDPIVVDLEHQQLAIEGIAVGVIRNADWM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1Y1</accession>
    <name>D0Z1Y1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Peptidoglycan D,D-transpeptidase FtsI</fullName>
            <ecNumber evidence="7">3.4.16.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Penicillin-binding protein 3</fullName>
            <shortName evidence="7">PBP-3</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ftsI</name>
        <name evidence="10" type="ORF">VDA_003545</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell inner membrane</location>
            <topology evidence="7">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the transpeptidase family. FtsI subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.4" evidence="7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303753.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003545"/>
    <dbReference type="EnsemblBacteria" id="EEZ42512">
        <property type="protein sequence ID" value="EEZ42512"/>
        <property type="gene ID" value="VDA_003545"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0768">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="213680at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008658">
        <property type="term" value="F:penicillin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008955">
        <property type="term" value="F:peptidoglycan glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009002">
        <property type="term" value="F:serine-type D-Ala-D-Ala carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000917">
        <property type="term" value="P:division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043093">
        <property type="term" value="P:FtsZ-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02080">
        <property type="entry name" value="FtsI_transpept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037532">
        <property type="entry name" value="FtsI_transpept"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005311">
        <property type="entry name" value="PBP_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036138">
        <property type="entry name" value="PBP_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001460">
        <property type="entry name" value="PCN-bd_Tpept"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03717">
        <property type="entry name" value="PBP_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00905">
        <property type="entry name" value="Transpeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56519">
        <property type="entry name" value="SSF56519"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="6 7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1 7 10" id="KW-0132">Cell division</keyword>
    <keyword evidence="7" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0133">Cell shape</keyword>
    <keyword evidence="7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="10" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="7" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0717">Septation</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="domain" description="PBP_dimer" evidence="9">
        <location>
            <begin position="70"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="Transpeptidase" evidence="8">
        <location>
            <begin position="263"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="7">
        <location>
            <position position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ42512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="576" mass="63024" checksum="ED83C8CF2392795A" modified="2010-01-19" version="1">MKFFKRSTRKNSKAKKASSAFIPWRFGVICGFVILGLAALIARTAYIQVLEPGRLIQEGDMRSLRVKPLPSARGIISDRNGEPLAVSVPVQAVWADPVNIFKHGGLSDVDRWHALADVLDWNRQELIHYIDKNKKRRFIYLARQVSPAMANYVNKLKLPGIGLKDESRRFYPSGEVSAQLIGVTGIDGHGLEGIEKSYDGWLTGEPGRRTVRKDRYGRVVENISVEKRQPGKSLQLSIDQRIQAVAYRAVKEAVRDLPATSASVVMVDVRTGEILAMVNAPSFNPNNRNDRESYKMRNRVITDSFEPGSTVKPLGVLTALDAGIANEHTLINIPGKHFRLGSKTITDVSRIEHQATMARILQKSSNIGMTKLSLAMPIENLISMYRRVGLDEPSGINLEGEIVGHFPNRRRWSDIERATFAYGYGLSVTPIQLVHAYATLGAYGIKRPLSILKTEKVVPGKQVVDPHLVKKVLLMLEGVADKAGGGGGWRASVPGYRVGVKTGTAKKAIAGGYGNDYFAYTAGIAPISNPRLAVVVLVNEPKGDKFYGGAVAAPILSKVLGSALHILNVPPDADTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z215</accession>
    <name>D0Z215_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001864</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40832">
        <property type="protein sequence ID" value="EEZ40832"/>
        <property type="gene ID" value="VDA_001864"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3247">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005325">
        <property type="entry name" value="DUF308_memb"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03729">
        <property type="entry name" value="DUF308"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="82" mass="8945" checksum="1233CF5F8E4E7B9E" modified="2010-01-19" version="1">MIFNGGTRVVFGLTNRALPGGKWIVLSGIISTAIGIYFFTLLDDPQFSLSLLGIFIGVSLLFEGFSFIFLGSQLKKQANKIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z286</accession>
    <name>D0Z286_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Zn-dependent protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_001929</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M50B family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298956.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001929"/>
    <dbReference type="EnsemblBacteria" id="EEZ40897">
        <property type="protein sequence ID" value="EEZ40897"/>
        <property type="gene ID" value="VDA_001929"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1994">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1015149at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008915">
        <property type="entry name" value="Peptidase_M50"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02163">
        <property type="entry name" value="Peptidase_M50"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="129"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="199"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="227"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="266"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="289"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="319"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M50" evidence="8">
        <location>
            <begin position="147"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M50" evidence="8">
        <location>
            <begin position="226"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ40897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="359" mass="39684" checksum="81921298E1B95B35" modified="2010-01-19" version="1">MELLNIRFLGKDLRLEGSMAGWQQLFWDNTLVSQIAASADNTPLHHQFELSNGEDTIFCELAISLSWQPFSLHYNATANQEVIVQGLRTEKDIEQQAPVETPKAERKFSLIGLVSLGMKALKSAKLIKVILASASLAAYSWLFSLKFALALIACLVFHEYGHVRAMKYFGMKTKGIYLIPFLGGLALSDEKINTRWQDVVISIMGPVFGLIMSILCTALYWLTGEMFFAGLAVFNALLNLFNLLPILPLDGGHILKSISFSMNSKVGITLCTIAAIAGVIISYQLGLTLLGFLLIMGCLEIGFEWKYRHHSHLLPLNRYGQIFSAVWYVGLVSALVSIIWYFAGTGDALLGLPLQVLGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2F3</accession>
    <name>D0Z2F3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Deoxyribodipyrimidine photolyase</fullName>
            <ecNumber evidence="9">4.1.99.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_000604</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DNA photolyase class-1 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the DNA photolyase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.99.3" evidence="9"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304843.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000604"/>
    <dbReference type="EnsemblBacteria" id="EEZ39584">
        <property type="protein sequence ID" value="EEZ39584"/>
        <property type="gene ID" value="VDA_000604"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0415">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="184000at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003904">
        <property type="term" value="F:deoxyribodipyrimidine photo-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901363">
        <property type="term" value="F:heterocyclic compound binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097159">
        <property type="term" value="F:organic cyclic compound binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051716">
        <property type="term" value="P:cellular response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036134">
        <property type="entry name" value="Crypto/Photolyase_FAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036155">
        <property type="entry name" value="Crypto/Photolyase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005101">
        <property type="entry name" value="Cryptochr/Photolyase_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002081">
        <property type="entry name" value="Cryptochrome/DNA_photolyase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018394">
        <property type="entry name" value="DNA_photolyase_1_CS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006050">
        <property type="entry name" value="DNA_photolyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11455">
        <property type="entry name" value="PTHR11455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00875">
        <property type="entry name" value="DNA_photolyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03441">
        <property type="entry name" value="FAD_binding_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00147">
        <property type="entry name" value="DNAPHOTLYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48173">
        <property type="entry name" value="SSF48173"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52425">
        <property type="entry name" value="SSF52425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00394">
        <property type="entry name" value="DNA_PHOTOLYASES_1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51645">
        <property type="entry name" value="PHR_CRY_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0157">Chromophore</keyword>
    <keyword evidence="5 7" id="KW-0274">FAD</keyword>
    <keyword evidence="4 7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Photolyase/cryptochrome alpha/beta" evidence="8">
        <location>
            <begin position="13"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ39584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="494" mass="57214" checksum="2FAC0821C5F78541" modified="2010-01-19" version="1">MQEKPSSIDQISSHNLMWFRSDLRITDNTALSEVCNQSLPVIALYIATPMQWHQHHVAPIQVDLIKRRLAVLTEQLAELSIPLIVLETEDFDSTVEKIEEICLMFNIASVHCNNQYLVNEEHRDQKLAANLKRYQISLVQYDDDCALAPGSVLNKQGEPFKVFTPYSKAWLKQYKQQTVEPTAMVGNTHKELSQEIEELLAVCGTVQHYDFQYPQVSSLTWPVDDEVILQHLYSFCCDKVGVYHQQRDYPSLEGTSTLSPYLAIGALSVRQCLKAVQQVDPSCLEINKECGGFVWVNELIWREFYHHLMAEYKHLCKGQPFQAYTQYVTWNEDSHYLKAWQQGKTGFPIVDAAMRQLQQTGWMHNRLRMITASFLTKDLLLHWHHGERWFLQHLIDGDFASNNGGWQWAASTGTDAQPYFRVFNPTTQGERFDPEGEFIRKWIPELVDVPNKYIHTPHLWHGDKKGYPAPIIDHKQARLRAIEVFKNAKEINTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2J6</accession>
    <name>D0Z2J6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000647</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39627">
        <property type="protein sequence ID" value="EEZ39627"/>
        <property type="gene ID" value="VDA_000647"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="88" mass="9771" checksum="D32042A3C8C9E43B" modified="2010-01-19" version="1">MMAAESLTGEVMSAHMIQQITAIERTELEIASQQIMVIEKALTQALVALEREDLVATREAIFNALYELNHQSPSIPKLMYENDPVLAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2K4</accession>
    <name>D0Z2K4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hypothetical DamX-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000655</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304970.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000655"/>
    <dbReference type="EnsemblBacteria" id="EEZ39635">
        <property type="protein sequence ID" value="EEZ39635"/>
        <property type="gene ID" value="VDA_000655"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3266">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1213917at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042834">
        <property type="term" value="F:peptidoglycan binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007730">
        <property type="entry name" value="SPOR-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036680">
        <property type="entry name" value="SPOR-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05036">
        <property type="entry name" value="SPOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110997">
        <property type="entry name" value="SSF110997"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51724">
        <property type="entry name" value="SPOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019931" evidence="2">
        <location>
            <begin position="25"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="SPOR" evidence="3">
        <location>
            <begin position="86"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="180" mass="20009" checksum="DE420F0E038301BE" modified="2010-01-19" version="1">MKLLSRKTVPALLASILLAGCSSADNPCDTGYLMPSKINGENFQCQQPETTAPETDYNDQTTDNTVTEEPAITEDNSVSSDEAYGSFDPSHYTVQVLALKRESDLHNYISLLPTNEPVWVNWNRVDGQSWFVVIMGDYPSREAARQAIGYLPSQVQAQGPFIRSFANVQADKETNVVRMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2Q4</accession>
    <name>D0Z2Q4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">EAL domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000705</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305110.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000705"/>
    <dbReference type="EnsemblBacteria" id="EEZ39685">
        <property type="protein sequence ID" value="EEZ39685"/>
        <property type="gene ID" value="VDA_000705"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2200">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EAL" evidence="1">
        <location>
            <begin position="30"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="285" mass="32765" checksum="5239DD1965619010" modified="2010-01-19" version="1">MQQGLKQNEWVVKTVDSILHTHEEIECHLSYDESSGIYVATYLGFIMKSAFQPIIHLDGSLMGYEALLRVYDKRSHVQCNTEQFVKSPFLSCHERLNIDTLARVLHLKNFFLHIAEGHLFLNTNPDAVIDSISIEYFNQFINNRIQPVGTAIDQIYLELLEYKCSSDQALTTSIQDLSKNGFKIALDDYGCKASSEIRARNVRPDIIKMDRSLLAQYVIGIEPPLLKAIKVARELNAEVLLEGVEDFNFYLKAKELDVDYLQGYFIGRPELVHYLSRPFEFFDKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2S8</accession>
    <name>D0Z2S8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Amino acid ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_000729</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ABC transporter superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305182.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000729"/>
    <dbReference type="EnsemblBacteria" id="EEZ39709">
        <property type="protein sequence ID" value="EEZ39709"/>
        <property type="gene ID" value="VDA_000729"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1126">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1191583at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015424">
        <property type="term" value="F:ABC-type amino acid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030679">
        <property type="entry name" value="ABC_ATPase_HisP-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039085">
        <property type="entry name" value="ABC_ATPase_HisP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="8"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="40"/>
            <end position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ39709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="246" mass="27515" checksum="146F083D8CBCD0DB" modified="2010-01-19" version="1">MSSNDAVIAFESIDKWYGDFHALKNINLSIQKGEKLVVCGPSGSGKSTLIRCINGLEQFDSGTLTVVGEPLTPQHLHSIRGQVGMVFQHFNLFPHMTVLENLTLAPIKVLKLTKKEAEQRALHFLDRVQIAHQADKYPSQLSGGQQQRVAIARSLCMKPDILLFDEPTSALDPEMISEVLDVMKSLADEGITMVCVTHEMGFARQVADRVVFMDEGEILEIAAPDDLFDRPQHLRTQQFLRKILSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2U6</accession>
    <name>D0Z2U6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional Regulator LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000747</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305237.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000747"/>
    <dbReference type="EnsemblBacteria" id="EEZ39727">
        <property type="protein sequence ID" value="EEZ39727"/>
        <property type="gene ID" value="VDA_000747"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1102730at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="290" mass="32230" checksum="1D5200A7EC75FB66" modified="2010-01-19" version="1">MNWDDTQYLLALGREGTLRKAAASLYVDQATVGRRIAALESHLKCQLFVRSNKGYELTFAGQQAFYEATKIELAVSFLVKKVKGFDQQLSGDVVISTTDSVAIDFVTTAVKQIRTIAPDLRIKLDVTTQICDMTKRNVDIAIRNIRPKNSDLIVKRLLKSPMYLYASEDYIGHNRPSKSVSSLDDLDLVVHAPMLEANASTLWGLSVENARIALLADSSLLLRSAIKGGIGVGFLPEFMAKKDNLVSILPDYHIDTDYELWMVTHADTMSSAKIRLVINILNEIFAKSDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2V8</accession>
    <name>D0Z2V8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cupin_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000759</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305268.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39739">
        <property type="protein sequence ID" value="EEZ39739"/>
        <property type="gene ID" value="VDA_000759"/>
    </dbReference>
    <dbReference type="GeneID" id="57343059"/>
    <dbReference type="eggNOG" id="ENOG502ZU7P">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1958309at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_2" evidence="1">
        <location>
            <begin position="38"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="122" mass="13827" checksum="46210D2424ABCE91" modified="2010-01-19" version="1">MALNEKVWSDMAVDPEAPQGFYFRDASCAQPITSMLEVWDAGTVEDPHHHPHDDMSVMVEGRIDVQFFDRQDDGSLIKKGDVQIFRKGDTAYIPANQIHSVIYTEDTKMVYVQDGEFGFIAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2X3</accession>
    <name>D0Z2X3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Maltodextrin-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_000774</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Binds maltose and higher maltodextrins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the bacterial solute-binding protein 1 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305313.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000774"/>
    <dbReference type="EnsemblBacteria" id="EEZ39754">
        <property type="protein sequence ID" value="EEZ39754"/>
        <property type="gene ID" value="VDA_000774"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2182">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1303718at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015144">
        <property type="term" value="F:carbohydrate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006060">
        <property type="entry name" value="Maltose/Cyclodextrin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006061">
        <property type="entry name" value="SBP_1_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00181">
        <property type="entry name" value="MALTOSEBP"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01037">
        <property type="entry name" value="SBP_BACTERIAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0574">Periplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0732">Signal</keyword>
    <keyword evidence="3 6" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="2 6" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013426639" description="Maltodextrin-binding protein" evidence="6">
        <location>
            <begin position="24"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00030303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="393" mass="42510" checksum="7A049F5FE7E9D364" modified="2010-01-19" version="1">MRKVLSTVALCTLAALGSVNAYAAIEEGQLTIWINGDKGYNGLAEVGKKFEADTGVKVTVAHPDALEEKFPQMASTGDGPDIIFWAHDRFGGYAQAGLLAEVKPTEAFKNKFTDFTWDAVSYNGKYIGYPVAVESLSLIYNKDLVPNPPKNWEEMAALDKELQKKGKRAIMWNLQEPFFTWPVLAADGGYAFKFTPNGYDAKNVGVNNEGAKRAMTFMKQMVDNGVIAADVDYAIAESGFNKGDVAMTINGPWSWANIDKAGVNYGVTVLPKLSGNPSKPFVGVLTAGISTASPNQDLAVEFLENYLLTDEGLATVNKDVPLGAVALKSYQKTLSKDSRIAATMDNALNGEVMPNIPQMSAFWYAEKAAIGNVLTGRQSVDDALNTVAERMTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z302</accession>
    <name>D0Z302_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sialic acid-induced transmembrane protein YjhT(NanM) possible mutarotase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000803</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305394.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000803"/>
    <dbReference type="EnsemblBacteria" id="EEZ39783">
        <property type="protein sequence ID" value="EEZ39783"/>
        <property type="gene ID" value="VDA_000803"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3055">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1977684at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019936">
        <property type="entry name" value="Mutatrotase_YjhT-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="SSF50965"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03547">
        <property type="entry name" value="muta_rot_YjhT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019958" evidence="1">
        <location>
            <begin position="24"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="383" mass="41750" checksum="BD0F20424DB9DD98" modified="2010-01-19" version="1">MLKFGPSFMTMVMGFTLSSAAYAVDEWPDLPVGVKNGVSAQVGSQLYVGLGSAGQQWYRLDLNQKSKGWQAVSHFSGPSRDGATATAIGKNIYVFGGSGKAKAQDKSPIIFDTIYRYQVDLDKWEEMDAHTPVGLLGASSYSPNGEEILFFGGYNKTYFDQYLASITAVDKDTQPEKWQSIVDGYMGMKPADYKWNNFVISFEPHTGFWRSLGEVPYSANCGAALVQNKKNAVIISGEIKPGLRTAEVKEYQFGTPSPWLKLNELPVPQGFTLQEGVAGSFAGMSHDAMIVMGGANFHGAQQAFAKGKMFAHAGLSKSYNPEMYVYQDKQWQQVNDFISGLAYGSSFTTSDGVLIAGGENSDGQASNKVYLLNWNGKTVDIVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z308</accession>
    <name>D0Z308_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000809</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305410.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000809"/>
    <dbReference type="EnsemblBacteria" id="EEZ39789">
        <property type="protein sequence ID" value="EEZ39789"/>
        <property type="gene ID" value="VDA_000809"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1552415at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="186"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="229"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="264"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="294"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="355"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="393" mass="44523" checksum="ADBFC852A3AF585F" modified="2010-01-19" version="1">MFCLSYIKREWQLIWQDGWLRALLIWLPITLFVTMWLIFSAGIARDLPIGVVDLDHSRMSRGLTRYFNASPTMEVTAQFTDRAAGDRALRGGDIYALVVLPDSLEKDTMLGYSPSVTVFYNSQFILIAKLLNSAMVQAQATYNASIETLRNMSHGSPVPLQALGQAVPVQSQITPLFNSNSHYGQFLVSAILPAIWQILIVATTVMTLAAEDRRQGLLNWLRERPYQKVMSKFVPYFFGFLIQGMLFLWGMYGVLDWPMHGSWLILFTAQSLMVLACISVGCLFYFVAMDTARAMSFVAGFTAPAFAFMGITFPATNMHPLAQMWRSLLPVSHYIEIQLQQVDYGTGWFQARDNLFVLALFIIALILGLVKMHFWRKGQLKHEAKLDVNKETL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z319</accession>
    <name>D0Z319_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000820</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39800">
        <property type="protein sequence ID" value="EEZ39800"/>
        <property type="gene ID" value="VDA_000820"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="40" mass="4629" checksum="B349970F0865F8ED" modified="2010-01-19" version="1">MYADLEPLIQEPVLQAPIQYGNGYNHGAMQMYTQQPYQKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z351</accession>
    <name>D0Z351_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000852</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305530.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39832">
        <property type="protein sequence ID" value="EEZ39832"/>
        <property type="gene ID" value="VDA_000852"/>
    </dbReference>
    <dbReference type="GeneID" id="57343100"/>
    <dbReference type="eggNOG" id="ENOG5031NG0">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2071325at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="86" mass="9596" checksum="08F4B4554176F04F" modified="2010-01-19" version="1">MRNLIAGFIAVVIGMFTLFFAAIMGLFVSVAALITKPFLKRKLAYADYAYQEQGFTDSRFGDARQEKTSASSNVIDGEFEDITDRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z357</accession>
    <name>D0Z357_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Putative pyrophosphorylase ModD</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_000858</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the NadC/ModD family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305548.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000858"/>
    <dbReference type="EnsemblBacteria" id="EEZ39838">
        <property type="protein sequence ID" value="EEZ39838"/>
        <property type="gene ID" value="VDA_000858"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0157">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1718114at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004514">
        <property type="term" value="F:nicotinate-nucleotide diphosphorylase (carboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006242">
        <property type="entry name" value="ModD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027277">
        <property type="entry name" value="NadC/ModD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036068">
        <property type="entry name" value="Nicotinate_pribotase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037128">
        <property type="entry name" value="Quinolinate_PRibosylTase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002638">
        <property type="entry name" value="Quinolinate_PRibosylTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022412">
        <property type="entry name" value="Quinolinate_PRibosylTrfase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32179">
        <property type="entry name" value="PTHR32179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01729">
        <property type="entry name" value="QRPTase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02749">
        <property type="entry name" value="QRPTase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006250">
        <property type="entry name" value="NadC_ModD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51690">
        <property type="entry name" value="SSF51690"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01334">
        <property type="entry name" value="modD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="QRPTase_N" evidence="7">
        <location>
            <begin position="18"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="QRPTase_C" evidence="6">
        <location>
            <begin position="106"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR006250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ39838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="286" mass="31146" checksum="DEAA601FE00DE286" modified="2010-01-19" version="1">MIYFSEQELDALLLEDIYRGDVTTRGLNLSHQEATMVFRRKHSGVVAGIDVSVRLLQKLGLTAYSYAKDGDIVDTGLTLIEAKGSADKLHQGWKVVQLVMEWCCGVAQYTHALVTQAKVINPNAIIACTRKSIPGTRKLATLAVLAGGGHIHRAGISETVLVFTNHRRLLTEPNNYAKQVQLLRQSAPENKITIEADSLADVVPIISAKPDIIQLDKFSIEDVNRALELVNSATQSITLSVAGGVNIHNIEQFASTGVNLFITSAPYYAQPTDIKVIITANSLETN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-06-02" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3C2</accession>
    <name>D0Z3C2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative small subunit bacteriophage terminase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000923</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000923"/>
    <dbReference type="EnsemblBacteria" id="EEZ39903">
        <property type="protein sequence ID" value="EEZ39903"/>
        <property type="gene ID" value="VDA_000923"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3728">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="265" mass="29862" checksum="9C24D35040CA4136" modified="2010-01-19" version="1">MAKDWSQLQQQFLIDNARTGITAKDWCERQGLNYQSARRYIKVRTAQKHSAHSAQRTAHDKTVRKANKTSKHSKGNRDNKNRLGRDSKGRFTEGNPGNTNIPTNAFEKGNQYSRKHGGYATRFDDCSLFDDAVEMSLQEELILCRARALSCIDTMKLIRIDLKNATSVEQRIELYNAIASTEQALDKNVIRIESITKTLSSIRIDDVNEYKIIADTSRIEAATNKLNLESDKLAKDGKGSITPISEMISELQEMGSDGLMSNIDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3F8</accession>
    <name>D0Z3F8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Galactokinase</fullName>
            <ecNumber evidence="8">2.7.1.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_000959</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.1.6" evidence="8"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000959"/>
    <dbReference type="EnsemblBacteria" id="EEZ39939">
        <property type="protein sequence ID" value="EEZ39939"/>
        <property type="gene ID" value="VDA_000959"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0153">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004335">
        <property type="term" value="F:galactokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006012">
        <property type="term" value="P:galactose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000705">
        <property type="entry name" value="Galactokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013750">
        <property type="entry name" value="GHMP_kinase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006203">
        <property type="entry name" value="GHMP_knse_ATP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006206">
        <property type="entry name" value="Mevalonate/galactokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10457:SF6">
        <property type="entry name" value="PTHR10457:SF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08544">
        <property type="entry name" value="GHMP_kinases_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000530">
        <property type="entry name" value="Galactokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00473">
        <property type="entry name" value="GALCTOKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="SSF55060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00131">
        <property type="entry name" value="gal_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00627">
        <property type="entry name" value="GHMP_KINASES_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0299">Galactose metabolism</keyword>
    <keyword evidence="3 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GHMP_kinases_N" evidence="6">
        <location>
            <begin position="62"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="GHMP_kinases_C" evidence="7">
        <location>
            <begin position="227"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ39939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="333" mass="36408" checksum="ECFC74CAA261AE7B" modified="2010-01-19" version="1">MVAAAKRDDNIVRVVSVDYDNAVDEFDITQEITFQQDKMWANYIRGVVKYLLARGYQFTGADISVSGNVPQGAGLSSSAALEVVIGQTFKVLFNLEISQADIALNGQQAENQFVGCNCGIMDQMISAEGRENHAMLLDCRSLETEAVSMPEDMAVVIINSNKKRGLVDSEYNTRRQQCEEAARIFGVKALRDVTIEQFNEKVSELDELVAKRARHVITENDRTVEAAQALRAHDMKRMGELMAESHASMRDDFEITVKEIDTLVDIVKQVIGEQGGVRMTGGGFGGCIVSLVPPSLVEDVKAAVESQYEAATGLKESIYVCQAKNGAGLVDAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3J8</accession>
    <name>D0Z3J8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000999</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305949.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39979">
        <property type="protein sequence ID" value="EEZ39979"/>
        <property type="gene ID" value="VDA_000999"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019969" evidence="1">
        <location>
            <begin position="25"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="187" mass="21293" checksum="B61D4C252817E0C9" modified="2010-01-19" version="1">MIYQKIALAGFTISTLFISQLSFADEDVYSITKSAQGSSFLFEKQVDSSIDISTSDLPLFHRRLVVNDNGLTEYHYIPVIKENKNKKWIEAKNQYSKNTLEAKSICGKLTTLGEKWHSPTAKEFNNAMNNWDPEFINLMQELANSYTTDGLLADGEWFYFKNTQQGHAQVKNDASSYEPKPTICIIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3K5</accession>
    <name>D0Z3K5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HTH lysR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001006</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305966.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001006"/>
    <dbReference type="EnsemblBacteria" id="EEZ39986">
        <property type="protein sequence ID" value="EEZ39986"/>
        <property type="gene ID" value="VDA_001006"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="990666at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="310" mass="34958" checksum="F8CF3B8BABE558B3" modified="2010-01-19" version="1">MKLSQLNAFKAVVECQTVTAAAERLNLSQPAVSRLLSALEDRLGFTLFVRSRNRLVLSVEGEAFYLEVAKVFEAVSDLDNVATSIRTNHFGSLHLAAMPLLSNAFLPRILAHFLKQTNQLKVGFKTYRSEEIIRRVQSQVVDIGFAFLPDTQPLPGVKAQRVECQCVAIVPIHSPLAHKSYLYLDDIADQLVIRHEKDTVQQRIDSLLQRHDLRTIEHIEVSLASTAAALVQEGIGMAITDPLTAYMSSEHTNVLTKPLNFHLPFEFDILYPAFKPIHRHAEVFIEQFMLQADAMDIQLKIGPMRDLNEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3S0</accession>
    <name>D0Z3S0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001071</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306146.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40051">
        <property type="protein sequence ID" value="EEZ40051"/>
        <property type="gene ID" value="VDA_001071"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019976" evidence="1">
        <location>
            <begin position="20"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="225" mass="24884" checksum="BEA38FEA91FE3379" modified="2010-01-19" version="1">MKRTSIAFILAIISQSAFSANGITEQDFDILNYGNVEQVRMTKAAGRDHWDVNYEYARQSGEQYEVKLHVKPIVNSQFSTQQVEPKTATLTVGPFKMPISLEAFNRFAEQPSELTDYLAHTLPMVPMDILGHTIKANIDDVSFDGKSAETIVSFSFESQEKIDYLPVTAGLAGIWTDGVPYPTMMASIAAGEMDADFVCNNATKKCSTKLFGTDDPSSQLFKITN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3S7</accession>
    <name>D0Z3S7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">PTS system N-acetylgalactosamine-specific IID component</fullName>
            <ecNumber evidence="10">2.7.1.69</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_001078</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.7.1.69" evidence="10"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306165.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001078"/>
    <dbReference type="EnsemblBacteria" id="EEZ40058">
        <property type="protein sequence ID" value="EEZ40058"/>
        <property type="gene ID" value="VDA_001078"/>
    </dbReference>
    <dbReference type="GeneID" id="57343453"/>
    <dbReference type="eggNOG" id="COG3716">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1632067at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103111">
        <property type="term" value="F:D-glucosamine PTS permease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008982">
        <property type="term" value="F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004704">
        <property type="entry name" value="PTS_IID_man"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03613">
        <property type="entry name" value="EIID-AGA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51108">
        <property type="entry name" value="PTS_EIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0598">Phosphotransferase system</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="209"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="246"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="277"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ40058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="297" mass="32111" checksum="122BE1562C029EFA" modified="2010-01-19" version="1">MASDITAGTLADKNTKTHVNLVDDVDAYEDTTPRKVITKKDLWICAIRGLFMEGNFNFERMQAGGFAYSIVPALKKIHGDNKRDFAKSLKNHLQFFNASPKLFTFLLGTAIAMEENKEKPSTVNVMKVAGMGPTGGIGDAIDHMTLMPLTLALGASIAMEGSIAGPFVFFFLYQIVHFAVYFGLMFMGYKAGTAAMVNMSEATEKLAKAANIMGIFVIGALSATFIKVQTTASIELGGKVVELQSALFDKIMPNLLPLALVFFMFKMVKGTGFWAKPPVLIFSTLAAGVVGHLLGIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3T6</accession>
    <name>D0Z3T6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pole remodelling regulatory diguanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001087</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306189.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001087"/>
    <dbReference type="EnsemblBacteria" id="EEZ40067">
        <property type="protein sequence ID" value="EEZ40067"/>
        <property type="gene ID" value="VDA_001087"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3706">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="4"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="125"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="3">
        <location>
            <begin position="280"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="406" mass="45844" checksum="6CF380B8E39CA290" modified="2010-01-19" version="1">MEHKILVVEDSRPFRRVLEVELRKAGYTPIFAESIADAEKILDQDLDFLCAILDYCLPDGQDGEVIDVCLSVGIKVIVLTALMDEMTRERVLAKTVIDYVPKDSPSCIASIIPILNRLGNNSQHKVLVVDDSITSRKYVRSLLERQYLNVVEACNGEQALDIFRKEKDISLIITDYTMPERDGVSLIKEIRKTHSPSEVAAIGLSASDEHALTAKFLKAGANDFLSKPFNQEEFYCRLHSTLNILDAERKLFNMANTDYLTQSWNRRYFFNHPATKKTSGPKCLALIDIDKFKLVNDTYGHHVGDMVLINFAKLLRTYFSDSLVARLGGEEFCIVFGNSQSIFLQRLEALQKELNTIPTVILNNDIEYTVSIGVTHGDQDIHTLISNADKCLYQAKEQGRNQIVVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3V2</accession>
    <name>D0Z3V2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="15">ATP synthase B chain</fullName>
            <ecNumber evidence="15">3.6.3.14</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">VDA_001105</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.</text>
    </comment>
    <comment type="function">
        <text evidence="12">F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the ATPase B chain family.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.14" evidence="15"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001105"/>
    <dbReference type="EnsemblBacteria" id="EEZ40083">
        <property type="protein sequence ID" value="EEZ40083"/>
        <property type="gene ID" value="VDA_001105"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0711">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045263">
        <property type="term" value="C:proton-transporting ATP synthase complex, coupling factor F(o)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015078">
        <property type="term" value="F:proton transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015986">
        <property type="term" value="P:proton motive force-driven ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028987">
        <property type="entry name" value="ATP_synth_B-like_membr_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002146">
        <property type="entry name" value="ATP_synth_b/b'su_bac/chlpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005864">
        <property type="entry name" value="ATP_synth_F0_bsu_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00430">
        <property type="entry name" value="ATP-synt_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81573">
        <property type="entry name" value="SSF81573"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01144">
        <property type="entry name" value="ATP_synt_b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="4" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 14" id="KW-0138">CF(0)</keyword>
    <keyword evidence="7 14" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 14" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 14" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00025614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEZ40083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="135" mass="15385" checksum="0AEBEC9DB79AC913" modified="2010-01-19" version="1">MKYIWPPLTELLDKRQREIAEGLIHSENAAKELELARANGDKLLNDAKKSASELVEQGNKRRSQIIDDAKAEAEAEKARIIAQGQAELESERNRIRQELRREMSDLVIETAEKLINQNLDSAANRELVNKLIKDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-12-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z411</accession>
    <name>D0Z411_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha-1,2-mannosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001164</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001164"/>
    <dbReference type="EnsemblBacteria" id="EEZ40142">
        <property type="protein sequence ID" value="EEZ40142"/>
        <property type="gene ID" value="VDA_001164"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3537">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005887">
        <property type="entry name" value="Alpha_mannosidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041371">
        <property type="entry name" value="GH92_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012939">
        <property type="entry name" value="Glyco_hydro_92"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07971">
        <property type="entry name" value="Glyco_hydro_92"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17678">
        <property type="entry name" value="Glyco_hydro_92N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01180">
        <property type="entry name" value="aman2_put"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro_92N" evidence="2">
        <location>
            <begin position="99"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_92" evidence="1">
        <location>
            <begin position="361"/>
            <end position="913"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="945" mass="105470" checksum="019F971456699E88" modified="2010-01-19" version="1">MLLGKIGLAESFCQPPYSLSLLAHEVLAKEMCAFKLNMEFIMFKPTLVAISIALSLGLVGCNSDNDNVDASGKQPIVNPDIDMGANPAIAFEDMDLTRYVNPFIGTGELGNTYPGATTPHGMVQLSPNNGSNGWEYISGYFYKDARMVGFSHTHLSGAGAGDLNDILVMPINTRSDYMLNEGSASLNVEASTFQHKNESATAGYYTVLLDSYDIKAELTASDRVGVHRYTFPQDEKSELIVNLGFKLNWDYTADSYFKWDKENNRLLGHRFSDGWAPSQKEFFIMEFDQPIKNIRFAYYDKDGKEYVDAPAGTTEIGGEIRGKHQYARAYVEFDTAQSELVVEAKLALSNVEIGENGESGASLNMTEVAGKDFDQVRKDATAKWEKELAKIKVEGDHEYKQTFYSALYHSLLGQTIHSDLDGRYRAVTRGRGAYPNGEFDNPILHDPVLIADANNDGVGDYTRYDTFSLWDTYRSVQPLSSIIEPDRLADVVLSFLSFAELKDESGNVVGRLPEWTFKGNETGMMMGMHSTPIIADVLTKGSLEKRMIDLGFSERERQDIKERLIDAMIKDGREDSAVDSIKEYVTKGYKSAKLREGEGDLWAHSPFESSWTASYSLEYAYNDWCIAQAIKAVRGDKVPEYQEFADRSNNWKAQFDFGGAKYQGWFKARDTEGKFIDAGWVDPKTGKAVGKDWRPDMFNYAFTESNGWQYSFSVQHDIHGLINHMTKFDQEVQDPKAQRGDLFAARLDEYFSTYPDRNAGDNQYPIFNTGNLGQHVQGNEPDHHVPYLYNYVGQPWKTQAVVASATNVCYNNTPDGICGNDDFGTMSSWFVFRALGFYPVSASAGIYEIGTPMFESANIDVGNGKTFTVTTDGVSRDAIFIQSATLNGKAFTRTYLTHDEIMAGGTLHFVMGEKPNKEWGTGKDDVPPNLGVGSFLHANEVQHTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4A8</accession>
    <name>D0Z4A8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Uroporphyrinogen-III C-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.107</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_000364</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="7">Porphyrin-containing compound metabolism; siroheme biosynthesis; precorrin-2 from uroporphyrinogen III: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the precorrin methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.107" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304161.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000364"/>
    <dbReference type="EnsemblBacteria" id="EEZ39346">
        <property type="protein sequence ID" value="EEZ39346"/>
        <property type="gene ID" value="VDA_000364"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0007">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1185397at2"/>
    <dbReference type="UniPathway" id="UPA00262">
        <property type="reaction ID" value="UER00211"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004851">
        <property type="term" value="F:uroporphyrin-III C-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019354">
        <property type="term" value="P:siroheme biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd11642">
        <property type="entry name" value="SUMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006366">
        <property type="entry name" value="CobA/CysG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003043">
        <property type="entry name" value="Uropor_MeTrfase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="SSF53790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01469">
        <property type="entry name" value="cobA_cysG_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00839">
        <property type="entry name" value="SUMT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00840">
        <property type="entry name" value="SUMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TP_methylase" evidence="9">
        <location>
            <begin position="15"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ39346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="253" mass="27604" checksum="5054010050EE7EAC" modified="2010-01-19" version="1">MTNASDITTTTGFVSLVGAGPGDPDLLTVKALRLIQQADVVVYDRLVSKEIMGLVNLTAELIYVGKQLDYHCVPQHMINQILCDQAKQGKQVVRLKGGDPFMFGRGGEELELLASEQIPYQVVPGITAATGCSAYSGIPLTHRDHAQSVQFITGHLQPNGQEHNWPALAQKNQTLVFYMGLKQCGYITEKLLQQGLLPTTSCAIVERGTTPNQRVLICQLNELPSLADQAESPALLIIGSVTSLHHQLKWFNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4B4</accession>
    <name>D0Z4B4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000370</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304176.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39352">
        <property type="protein sequence ID" value="EEZ39352"/>
        <property type="gene ID" value="VDA_000370"/>
    </dbReference>
    <dbReference type="GeneID" id="57343249"/>
    <dbReference type="eggNOG" id="ENOG5033EWY">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2048406at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="105" mass="12776" checksum="2DA6A89D283AD606" modified="2010-01-19" version="1">MSHFNSQEHKGSQGGHQHGAEFEHEKMERRYDDGVEHKHNRDHHQMRDHEESHPHTQHGGDPKGHKHPEQTHHERHEHDEHRHHKTKEHDHKEHSREHHKTGHHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4H5</accession>
    <name>D0Z4H5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000433</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304350.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000433"/>
    <dbReference type="EnsemblBacteria" id="EEZ39413">
        <property type="protein sequence ID" value="EEZ39413"/>
        <property type="gene ID" value="VDA_000433"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1361">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3292">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3391">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4719">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="480421at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045474">
        <property type="entry name" value="GEVED"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20009">
        <property type="entry name" value="GEVED"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GEVED" evidence="1">
        <location>
            <begin position="253"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="domain" description="GEVED" evidence="1">
        <location>
            <begin position="441"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="domain" description="GEVED" evidence="1">
        <location>
            <begin position="629"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="domain" description="GEVED" evidence="1">
        <location>
            <begin position="827"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="domain" description="GEVED" evidence="1">
        <location>
            <begin position="1408"/>
            <end position="1487"/>
        </location>
    </feature>
    <feature type="domain" description="GEVED" evidence="1">
        <location>
            <begin position="1866"/>
            <end position="1948"/>
        </location>
    </feature>
    <feature type="domain" description="GEVED" evidence="1">
        <location>
            <begin position="2336"/>
            <end position="2420"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="2808" mass="298365" checksum="959B69C0A42A332B" modified="2010-01-19" version="1">MVIINRLTKITFLFFLLFSSFVWGEANIQGMTISANQCGQQMTGSIWVVDWSDGNGNVDKDFDFNLNLPPGVSLTNVVGDVCGSCGFQSLNWSGNRIWGRIQSGHINAGMNIWLSGPTQTIVNYTISAYNIGGNTSSNTISVYCDDHGDAPSSYGLAGHTYTSTTKTMRIGNVDIDYENSNLSNSTATGDDNSGTNDEGTGVVITPWELGATCSGLVQDTTTGIVALSTITMDENTYCIEVPARNVSGSGAMLAGWLDWNNNGVFDNPTERSQLMPGMANVPSGTNGDVYVIWWDNIIATEINTFIRLRITNQSSFITNPFPTGSVSWGEVEDHFIEFADFGDAPDPSSGTSLNNYNTRENDNGAKHLDPFIDIVFLGSQQPDYDSGLLQNANADADELDNMADEDGLSSDPWTVVGATNYDLAVLCNDFDSSSGGDLGATVYGWIDFDQDGIFETNAQADCIDTNDGSGSLNDGIANLTFSGFITPTTTSTTYLRLRTCSTGDCATPTGTASDGEVEDYLFDIRQIDFGDAPDDGSDNTYHTLLSSDGASHSNASTPSIYLGSIAPDSDLGLNQSVTADLDDTTDTSILSVGNDEDAVAGVVFDSAKNIFTLTIPCNDNDTGVDLGATVYGWIDFNQNNRFEESEFTSRECIDTDPSNPGSALLRWIDIDNVQEGTTYLRLRITDSVLPFDDIATNWDERSAGSVVNGEIEDHVITFSQESDFGDAPDSYQTLASSGGAEHGLGGNRYTIYLGNTAPDADSDGFSDGIEDFPNTALDDDSNDTSGIASGNDEDAVTGMEGLFLDSTTYQINAICNDHNGTTDLAATVYGWVDFNADGDFSDSGEFAQISCNDIDSNSDGSALLAFSGFTVSATPTTSFARLRITTDSLTANDYAGVASDGEVEDFTVIIGRRISGKVFNDLGTDTSFSTAYPFYNGSLDIGEVGIAGVVITLFDQTSGTCQSTLTDSNGDYSLAALDGHSYQLFETANETLPAPSICPPQVGAVNTDGLLINNTIADPDGYGSSSANIISLGVITGDSSNNNFADFLAPEFASCDADGYLTLRTPADLFAVDLFSGATEELAPDTTADYNNNGLQVGYAMQTNHIIGDISGTNLRVIALVDGDYNVHLLPITLTGSNININFNNATISDDGILYMTGGGTGYILMVDVNPANETYLQEIGRPSISAFSTADFAINPVDGKIYGLRANGVIAIYDPVTQTRDNSKSVTQVIENGTTRTYSGSHFSSSYGAIYFDQAGNMYAVNNGNYSPPTPSIAAPVLQIPIGNGASANYTATIVSNLGFTMSTNDGARCRYAPLGLDFGDAPDSFITSYADVGPHHITRGNSIWLGIENTDNDVDGYGSTDADSDDLSGTTPDDEDAFGNQVRVFINSGAGSLDVPFTNNSAKAATVYVWVDFDQNGTFEAVERASGAILASQTVGTVTVTWSGLASVVTGDTYIRLRICTDDAASGCSSPTGLASNGEIEDHTAKVIEGVFPDTTCDGIYQTSSTTGTNYQFDRIDLSTVPFSPVSVFTNQAGYDSLNGIAFDLAGGAFYGAFFDGSNTLHIALFDKQGNIVDLGMPTAAENFNIVDVRTGVITSITSGDPIIVSSDIVGDQGAISDDGQYLYLGHPNSGQILQVDLNSFTVQAINILLPDLGMTVGGGISLPFDGDWVYDSQSQELCSAEISTQTLYSVNPQTGAISAMALNFDSTPPIASSYGMVKGEDGHLYVVIDGDYDSDGNGSLDSTGQALYQINTKSKQAIFIESISSITSTYADAAGCITTATDYSDAASSYGVASHLYTDSNNNGITDFYLGNLWDSEFIAHQSVTARDDNLHSLIDEDGVIFPAVMTSGNNEITVITNQAGVINLWLDYQKGGSFESSEQLLINYPVTSGSQTLSILLDSAAMGSYSGATIARVRFCSTVNLCDKANDVEQGQQAGDGEVEDYQVWTSTNTLVSETCDSAILSHGASGVFTLEALDPTTTPPFSTNILQNPVTINDLTNFNSLNALGIHPETYLIYGIAMDTSTPERDIHLLITDQSASEVIDLGTVASSQNQTLTHNTVGTVSFSKGQILTRDVGGQIIQSAARGAVDPTGTYLYIHHQEWHQMIRIHLVERIFDVVSFSSPVNGMGGDMAFASDGYLYNPDVSNSLIYQLDVTTGTISSQAMVWNGVSPPQNGGGFGAVFMDNGIFMYAISNTGDHDLNRDGSIDFTGSAMYRINLHSGDIVPIGAMANAYPNSFDAAGCFESVDHGDTNLITDGTARHYFYDNNGDGEADYRLGLLIDPELAQPDDPNATGDDLLDIDDEDGVVMPASIVVNSLVNVDVNVTSQDLSSLKLNVWADLNGNGSYRDSGEQVVNELDVIDGTNSVQLLLPAAFTSGYNGNTTMRFRLCANADECNQPDDTSLGEIAINGEIEDYQFELINQILIRGIIFEDNAAGGGVAHDGIQSGAETGLSGFIVQAIYQGITQGSYTSGDILATTRSRGDGSYELLLPVEVASQPVLLNVIPQATWIDISESDVSAISQVQSSNVTDNQMVITANAGDTIESLDFGKVRSPRLEADNFTEIEPGQFVNFSHKLITYTSSDVLLSIANMVADPNISEWSAQIYQDANCNGRVDSGDNAITSVISAVGSIEVCILSKVYAPISAPLNAIFHYNLTALATFTDPAITNHGVTRSLSNTDTVKVSFQGAGQLKLEKKVTNITQGTEKGVSNQGRPGDILEYEIIFSNVGTGNITDISISDDTPSYTELESVVDCNNGVIPSSISLCNIETEHGVNNSGYQGNIKWILSGVLEPNSSGVLIYRVKII</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4J7</accession>
    <name>D0Z4J7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hypothetical transcriptional regulator LysR family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000455</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304412.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000455"/>
    <dbReference type="EnsemblBacteria" id="EEZ39435">
        <property type="protein sequence ID" value="EEZ39435"/>
        <property type="gene ID" value="VDA_000455"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="750230at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="289" mass="32560" checksum="B9EAFC69CDDC8DD7" modified="2010-01-19" version="1">MDTELLKTFLEVTKTRHFGRAADNLYLTQSAVSFRIRQLESQLGNPLFSRQRGNVHLTAAGERLRPYAEAILQTWGRAKQDVALSENLNSQIAIGASPLLWEFDGISDWINRVYGAVPGLALRLESVAREGMAKKLFNRNIDVFLTSEPPKIEQLKVAKVRDYQLQLVSSCENCELEQVRQLPLVYLDWGTRFSVEHSRIAELQRTPVLHTHSSKMALDYLIGSGGVGYLPSLIVADAVANQQLFLVEDAPVMEQSLYLVWCDDNEKRELIDAIVEVPFNSVIEISTSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4P8</accession>
    <name>D0Z4P8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycine cleavage system H protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_000506</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GcvH family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000506"/>
    <dbReference type="EnsemblBacteria" id="EEZ39486">
        <property type="protein sequence ID" value="EEZ39486"/>
        <property type="gene ID" value="VDA_000506"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0509">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005960">
        <property type="term" value="C:glycine cleavage complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019464">
        <property type="term" value="P:glycine decarboxylation via glycine cleavage system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06848">
        <property type="entry name" value="GCS_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002930">
        <property type="entry name" value="GCV_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033753">
        <property type="entry name" value="GCV_H/Fam206"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11715">
        <property type="entry name" value="PTHR11715"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01597">
        <property type="entry name" value="GCV_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="4">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="88" mass="9400" checksum="A1523992C1319CF8" modified="2010-01-19" version="1">MDLPEVGDTIDAGETFSLVESVKAASDIYAPITGEILEINEELGDSPELVNDEPYEGGWIAKVKLTDPSELDALIDGESYLATLAEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4W6</accession>
    <name>D0Z4W6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Type III secretion inner membrane protein YscQ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000199</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FliN/MopA/SpaO family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306585.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000199"/>
    <dbReference type="EnsemblBacteria" id="EEZ39183">
        <property type="protein sequence ID" value="EEZ39183"/>
        <property type="gene ID" value="VDA_000199"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1886">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1875967at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030254">
        <property type="term" value="P:protein secretion by the type III secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001543">
        <property type="entry name" value="FliN-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036429">
        <property type="entry name" value="SpoA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003283">
        <property type="entry name" value="T3SS_OMP_SpaO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013385">
        <property type="entry name" value="T3SS_SpaO/YscQ/SpaO"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01052">
        <property type="entry name" value="FliMN_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01339">
        <property type="entry name" value="TYPE3OMOPROT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101801">
        <property type="entry name" value="SSF101801"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02551">
        <property type="entry name" value="SpaO_YscQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0843">Virulence</keyword>
    <feature type="domain" description="FliMN_C" evidence="3">
        <location>
            <begin position="246"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="321" mass="35930" checksum="B21109C1B22EEF40" modified="2010-01-19" version="1">MILDFPKVEPSSIALSNQLCAKQCHFQDSQSNSLSVTLGQKPEFSGYRLTLLIGGQTIQIDFSGAQLQQWLHGILDSTAFESLPNSLQLALLSSQIEPYTDMIKRLFGQLPALSKLQVHEQPASEENVLMLTINRDGVSLSLWVHEGRDVLIDTLPQAPSYLSQNIALPFWLSFGKTRLALSQFEQLELGDVVFFDDCYIAQHQVLLQVSNHNLWRCQLDNTTLHIQEKETNMNDINSSEALTDHQQLPIELTFDVGQQTITLEQLNALQPGFTFELNQPISDPVTMRANGKIIGECELVNINERLGVRVLELFGGSQEPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4X2</accession>
    <name>D0Z4X2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000205</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306600.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39189">
        <property type="protein sequence ID" value="EEZ39189"/>
        <property type="gene ID" value="VDA_000205"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="64" mass="7265" checksum="478D83AAE1A81929" modified="2010-01-19" version="1">MDNVTQLLNTQYDIAPPKDHDEEIALIYQYLIDKFGDTSTTAFKLHEVLISLAHIAERDGATPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4X6</accession>
    <name>D0Z4X6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Outer membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_000209</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell surface</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306612.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000209"/>
    <dbReference type="EnsemblBacteria" id="EEZ39193">
        <property type="protein sequence ID" value="EEZ39193"/>
        <property type="gene ID" value="VDA_000209"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1196">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2169930at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005594">
        <property type="entry name" value="YadA_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03895">
        <property type="entry name" value="YadA_anchor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003020092" evidence="6">
        <location>
            <begin position="33"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="YadA_anchor" evidence="7">
        <location>
            <begin position="215"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ39193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="273" mass="28660" checksum="5430425C008B6AB9" modified="2010-01-19" version="1">MMNKNKIASGSLGLLALSIAVATGVFSTNALAAVETRASTQNATKISKNMESITANTKSITANTKSINGLSERITGEAKSTDIRFAQTYKGIGNNTTKIATNTKSINGLSERITGEAKSTDIRFAQTYKGIGNNTTKIATNIKSIDDLQHSTTENEARSVSNANKIADNSKRLDLSDKWQKMADQRLSDLEGDVRHNRKVAARGTAGVAAMANIPTPAIPGSTSFGVGIGHYDSESALAVGMSHYFENGISIKGSAGLTSGQSILGAGISKTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z500</accession>
    <name>D0Z500_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted manganese transporter 11 TMS</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000233</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306682.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000233"/>
    <dbReference type="EnsemblBacteria" id="EEZ39217">
        <property type="protein sequence ID" value="EEZ39217"/>
        <property type="gene ID" value="VDA_000233"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2248">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1784762at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021552">
        <property type="entry name" value="ArsP_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11449">
        <property type="entry name" value="ArsP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="209"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="240"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="290"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="320"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="379"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="403" mass="44057" checksum="CF5B25890AED7142" modified="2010-01-19" version="1">MDTSIQKLSKLVQQQSWQLTNKRLILPVIILALLISTSSLRELTIQVLADGFWQVAAYVAATLAVYEFISTKLKHRESQITKLIEHSVTGQIVFSALMGALPGCGGAIIVMTQYVNGKLPFVAVVTVLTATMGDAAFLLLATKPTVGLFVIMISTVVAILSGLVIYKVHGVHFLKRVQHVNEFVEIKNCCCQSSSQDTTPILIKLQSKFWQWILIPAITIALLGSFQIDTNHLFNLPANTIEIVGAVAAIITIFLWALSREVSDYQSMVSEDPKKPNDKAFNRIALDTNFVLSWVIGAFLAFELMLYWTQIDLNQLFNHWGILLPLIGVAIGLLPGCGPQIIVTSMFLAGTIPLSAQLGNAISNDGDALFPAIALAPKAALIATLYSSLPALLTAYTYFYLFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z552</accession>
    <name>D0Z552_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Flp pilus assembly protein TadD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000102</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306853.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000102"/>
    <dbReference type="EnsemblBacteria" id="EEZ39086">
        <property type="protein sequence ID" value="EEZ39086"/>
        <property type="gene ID" value="VDA_000102"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5010">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1747400at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003020103" evidence="1">
        <location>
            <begin position="22"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="242" mass="27742" checksum="4279A2FD3ADEF679" modified="2010-01-19" version="1">MHKFIYIIFLSLLVLSGCSSSSLDNSQAREIMLKSTKNYPDLINFYKEKIKKQNLDLDKNKLAQVYLDYNDPESALFIVNNIPNHMNNVESLIIMTNAFFDLGNNKEALNIAKKANVLEPNRGDIENLIAIIYASNGDIKNAREFFNMARLHLYDDIKIKNNLAVLDILDEDYTMASNKLIELYAKNRNDNEIYSNLVLALSKSNNIELLEKILKPKFNNDEINHKYDLLKTANISSSLLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z575</accession>
    <name>D0Z575_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000034</name>
        <name evidence="2" type="ORF">VDA_000125</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000005">
        <property type="protein sequence ID" value="EEZ39049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39049">
        <property type="protein sequence ID" value="EEZ39049"/>
        <property type="gene ID" value="VDA_000034"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39109">
        <property type="protein sequence ID" value="EEZ39109"/>
        <property type="gene ID" value="VDA_000125"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="57" mass="6250" checksum="3CC06449B4A0B879" modified="2010-01-19" version="1">MLISQNTRPQSPKNSSTMPKSVQFLVRVLTLSSSRKLGASSKLCAPFRVNKSSIPMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z592</accession>
    <name>D0Z592_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Mfp1 (Mar binding filament-like protein 1)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000051</name>
        <name evidence="4" type="ORF">VDA_000142</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000005">
        <property type="protein sequence ID" value="EEZ39066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306968.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000005.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000051"/>
    <dbReference type="EnsemblBacteria" id="EEZ39066">
        <property type="protein sequence ID" value="EEZ39066"/>
        <property type="gene ID" value="VDA_000051"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39126">
        <property type="protein sequence ID" value="EEZ39126"/>
        <property type="gene ID" value="VDA_000142"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031MUC">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021104">
        <property type="entry name" value="KfrA_DNA-bd_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11740">
        <property type="entry name" value="KfrA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="KfrA_N" evidence="2">
        <location>
            <begin position="12"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="86"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="314" mass="36299" checksum="0119D0812D8C59DE" modified="2010-01-19" version="1">MGISLSGEQLQDKVTMICNDLYSKGQKVSVRIVLSMLPDVSSTSTVHKYYKTWKDELEANQKSLLEKMGFSEEFTRVFMTEITRHATEAERRYRDMADDAKEQSQQAIDDLERAEDRLYKQTALLEQREKQIKNLEAELAQTENAQLAITQELRQQIESLTDQLNESTVSNERLRTELAKNEIKLESNALIVEESKNKNTELNEQVKSLNDKVIAQAQELTRFESKQESQELLLSELRETKAALQMANSHLDNELRQLQQERHTLNSHLNDAKSNGVTLSNRLEQASEQIAELKAQLHQNDEMIKRYETLLKNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5F4</accession>
    <name>D0Z5F4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000061</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000006">
        <property type="protein sequence ID" value="EEZ39006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005307124.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000006.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39006">
        <property type="protein sequence ID" value="EEZ39006"/>
        <property type="gene ID" value="VDA_000061"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5030A8C">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1084291at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="195" mass="22719" checksum="794FDC9A3662FAAB" modified="2010-01-19" version="1">MPFLIDDVDFSDLLKKPSTNKQAAKSFLAKYPKDYAIEGFNVPQGFRLVSAKSEKSIRLIDIRDRAEPRIVYAVDIILTGEIINNRFCTQVMVWASPSNEDLLIGLPRKVFNHFLERYIIVVSDDEQTADGKRFWERRISNAFSDDNHVYYIENEQFREILSVDDFFENFESIGWGKSEAHKERLFAISKIQLLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5H1</accession>
    <name>D0Z5H1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Conjugative transfer protein TrbL</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_000078</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000006">
        <property type="protein sequence ID" value="EEZ39023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005307169.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000006.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000078"/>
    <dbReference type="EnsemblBacteria" id="EEZ39023">
        <property type="protein sequence ID" value="EEZ39023"/>
        <property type="gene ID" value="VDA_000078"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1182284at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030255">
        <property type="term" value="P:protein secretion by the type IV secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014150">
        <property type="entry name" value="Conjugal_tfr_TrbL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007688">
        <property type="entry name" value="Conjugal_tfr_TrbL/VirB6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04610">
        <property type="entry name" value="TrbL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02783">
        <property type="entry name" value="TrbL_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003020116" evidence="7">
        <location>
            <begin position="20"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="43"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="77"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="143"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="205"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="239"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="281"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="384"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="389"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ39023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="431" mass="45042" checksum="55D9B84ED0D8A8B2" modified="2010-01-19" version="1">MYRIYLIFCLLLFSPLSLASQSDNAVDKIMQRFYEQTSAWEPIIHKYTMSLFVGLVTISFVWGAAQVLLKQGGVVDAIVFLFQSTMSIGVSIYLLSDGPNLSRALIASFSKISGILAGTNQQFSPSDILEFGLSIATKIWDKASAFSIINGILLSVVGLVIIVIFAMIAAEMIVLIVGAYMLVSGGTIMLAFLGSEWTRNYAMNYFTSVIGIAAQLFFMQLTVLIGYQVFSAYLTLEDTSLASIAMLLAMAIVYFALIKVMPNIASSLATGNFRFGSGSAVAAATAIAGAAAGAGLLASGVAGGASGAAMSKFMASDAGKNILSKFSSATQSAMSHSPQSFAAMKGAQGAAKVMTGAGSVAGKAAKVGMQALANQSPIGRALSQAHRSMGGANRPNPNTNDSTTATPTMADAKKNQASRNLAKAMMDELNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5H7</accession>
    <name>D0Z5H7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000084</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000006">
        <property type="protein sequence ID" value="EEZ39029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005307186.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000006.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000084"/>
    <dbReference type="EnsemblBacteria" id="EEZ39029">
        <property type="protein sequence ID" value="EEZ39029"/>
        <property type="gene ID" value="VDA_000084"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031NQ3">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2143803at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="377" mass="42083" checksum="EB1D9769DBD86770" modified="2010-01-19" version="1">MNIATFFKASIQTVSKESFKRQHPSPYLYFTIRNGFYHLYTSQEPSFALAEAWLKKINSSEWGLIEPLDNNQFFFMFVGKGDIIKAYVGSFEQLDSVLLERCKVLYIVDSNQLASSLESSQHQALLKYHVEPLSPLTPSELAPFALKKHKKIPIKAISLLALLTILGIAGSYAYREATKPEPLPPPVDPYLAYRTTVNQSFFAPEILHNALSLGAIGSGLPYGWQFKTVSLQGDAINLTAERTSNGQRTVIMSWLKQHPQLLPYSQVSLDSLSITIPLLQTLQKWHNKIMPTEPSLSSVIDTQVALGWQMTELTTDNGLVSTTSHWTATKETALSELASFSQMVSQLPVTITKLDITPSGAVGYFKIQIRFAFMGQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVK0</accession>
    <name>D0YVK0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative Ser protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001580</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298321.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001580"/>
    <dbReference type="EnsemblBacteria" id="EEZ40554">
        <property type="protein sequence ID" value="EEZ40554"/>
        <property type="gene ID" value="VDA_001580"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2766">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="49410at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013153">
        <property type="entry name" value="Prk_AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010650">
        <property type="entry name" value="PrkA_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016230">
        <property type="entry name" value="Ser_kinase_PrkA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08298">
        <property type="entry name" value="AAA_PrkA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06798">
        <property type="entry name" value="PrkA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000549">
        <property type="entry name" value="Ser_prot_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00763">
        <property type="entry name" value="AAA_PrkA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AAA_PrkA" evidence="1">
        <location>
            <begin position="19"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="644" mass="74380" checksum="0F2E5DE385C01D17" modified="2010-01-19" version="1">MSIFDHYRQRYEEAKDEELSLQEFLDICREDRSAYVNAAERLLMAIGEPEMIDTALDPRLSRLFSNRVIARYKTFEEFYGMEEAIEQIVSYLKHAAQGLEERKQILYLLGPVGGGKSSLAEKLKSLMQKVPIYILTANGERSPVNDHPFCLFDKNEDGDLLKNEYGIPKRYLNSIMSPWAAKRLHEFGGDITKFKVVKVRPSILDQVGVAKTEPGDENNQDISSLVGKVDIRQLEHFSQDDPDAYSYSGALCKANQGLMEFVEMFKAPLKVLHPLLTATQEGNYNGTEGLSALPFDGMILAHSNESEWQSFRNNKTNEAFLDRVYIVKVPYCLRISEEMKIYEKLLQNSQLSTAPCSPSTLDILARFSVLSRLKEPENSSVYSKMRVYDGETLKDTDPKAKSYQEYRDYAGVDEGMNGLSTRFAFKILSRVFNFDHSEVAANPVHLFYVLEQQIEREQFPQDLADKYLEHLKGYLIPKYVEFIGKEIQTAYLESYSEYGQNIFDRYVSYADFWIQDQEYRDPETGQLFDRAALNNELEKIEKPAGISNPKDFRNEIVNFVLRARANHSGKNPNWTSYEKLRTVIEKKMFSNTEELLPVISFNAKTSSEEQKKHDDFVARMMEKGYTRKQVRLLSEWYLRVRKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVP4</accession>
    <name>D0YVP4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Quorum-sensing regulator of virulence HapR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001209</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297642.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001209"/>
    <dbReference type="EnsemblBacteria" id="EEZ40187">
        <property type="protein sequence ID" value="EEZ40187"/>
        <property type="gene ID" value="VDA_001209"/>
    </dbReference>
    <dbReference type="GeneID" id="57339935"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="15"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="198" mass="22812" checksum="CCB6FC799D353B56" modified="2010-01-19" version="1">MDMVIKRTRTRLSPEKRREQLLNSALDVFARRGIGRGGHADIAEMANVSVATVFNYFPTREDLVEQVLIHVESRFNKLLTHSLNDEMPTAKAKLTNLTDCLIKAVIEQHDWLKVWFEWSTSVRDDIWPLFIKTNKNNLQKLTSVFEQGLTAGEFSRSQSASDLAHMFHGTCYVLYLQTHLTLDPEIMQRQADSYLQSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVR7</accession>
    <name>D0YVR7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative ATP-dependent helicase HrpA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_002008</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002008"/>
    <dbReference type="EnsemblBacteria" id="EEZ40976">
        <property type="protein sequence ID" value="EEZ40976"/>
        <property type="gene ID" value="VDA_002008"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1643">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011709">
        <property type="entry name" value="DEAD-box_helicase_OB_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024590">
        <property type="entry name" value="HrpA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010222">
        <property type="entry name" value="RNA_helicase_HrpA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11898">
        <property type="entry name" value="DUF3418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04408">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07717">
        <property type="entry name" value="OB_NTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01967">
        <property type="entry name" value="DEAH_box_HrpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="2">
        <location>
            <begin position="67"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="3">
        <location>
            <begin position="261"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="959"/>
            <end position="986"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="1278" mass="147757" checksum="83E76C1DCF9DCB2C" modified="2010-01-19" version="1">MRDQFRLHRRLQGAARIKNDQAKHAVFDEIATDIAKSMSVVELRRTQRPTVTYPELLPVSQKKDDIAEAIKHNQVVIVAGETGSGKTTQLPKICLELGRGVKGMIGHTQPRRLAARSVASRIAEELECEMGSYVGYKVRFNDQVSDRSQIKLMTDGILLAEIQHDRYLNQYDTIIIDEAHERSLNIDFILGYLRELLPKRPDLKVIITSATIDPERFSKHFNNAPIIEVSGRTYPVDVRYRPIVEDSDDTDRDQLEAIFDAVDELCDEGQGDILIFMNGEREIRDTADALEKRKLRDTEIVPLFARLSAGEQNRVFQPHTGRRIVLSTNVAETSLTVPGIKYVIDPGTARISRYSYRTKVQRLPIEPISQASANQRKGRCGRVQEGICIRLYSEEDFLSRPEFTDPEILRTNLASVILQMTAIGLGDIQAFPFVEAPDNRNIQDGVRLLEELGAINANAKDPRKRLTSVGRQLARLPIDPRLARMVLEAPKNNALREVMIIASALSIQDPRERPMEKQQASDEKHRRFYDKESDFMTFVNLWDYVQEQQKALSGNQFRKQCKKDYLNYLRIREWQDIHFQVRQVVRELELRINDTEAGYDAVHMSLLSGLLSHIGMKDQEKNEYQGARNARFNIFPGSGIFKKQPKWVMVAELVETSRLWGRIAAKIQPEWVEPLAQHLLKRSYSEPHWEKKSAAVHAFEKVTLYGIPVVAKRKVNYGRIDPTISREIFIRSALVEGDWDTKHKFFQQNRKLLREVEELEHKSRRRDILIDDEQLFEFYDQRIDLSVVSGRHFDTWWKKASKENPELLNFEREMLFRNDASHVTDLDYPNFWHQGNLKLKLSYQFEPGEDNDGVTVHVPLAILNQVEPDGFDWQIPGLRHELVVALIKSLPKTLRRNFVPAPNYADAFLSRTKVMEAPLLDSMEKELKRITGVTILREDWNLDQIPDHLKITFRAVDHRNRKLRENKDLYELKDSLKEKVQQTLSQVADDDIEQEGLKTWSFGTLPERYQQKRGGFEVRAYPAIVDNNDSVGIKLFETEEEQHRAMQQGQRRLILLNIPSPIKYLHDNLPNKSKLGLYFNPYGRVLDLIDDCIACGIDKLIEQKGGIVWQPEAFEALKDYVRAELGDTVVEIAKQVEEILTTAFNINKRLKGRVDLTMAFALSDIKAQLEGLIFKGFATECGWKRLPDILRYMRAIERRLEKLPIDPNKDRVHILKVESMVNEYKELLNKIPKGQPIPENVKEIRWMIEELRVSYFAQQLGTPYPISDKRIRNAINEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVS5</accession>
    <name>D0YVS5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001990</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299108.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40958">
        <property type="protein sequence ID" value="EEZ40958"/>
        <property type="gene ID" value="VDA_001990"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5032XNR">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1927439at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025332">
        <property type="entry name" value="DUF4238"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14022">
        <property type="entry name" value="DUF4238"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="335" mass="39198" checksum="87AFE2E622B79CC4" modified="2010-01-19" version="1">MPEASKKHLEAKKNHHHVWANYMRRWSPDNKQVYYTTKKNNDIRLDSVKSIAVERDFYRVKPLKPEHVQVIRIWSLKSPKDLHELHMSYLNDYLKMQYMESLYVQSGKKDETVDKLIEAWKSNGIENYHTAHENEVQEILEALANRDLSILDKDDNMIKFMQFFGHQIARTKNFKDTISNAADNHIKTLTLECWWFIGYMFGMSIGRSLYLDRKDDTHCLLINDTDIPFITSDQPIVNVHPALTAEVKPPEDHECDFYYPISPNVAYMINKSSRFPCGMVQVSVDVVEEMNINIAKRANFHIIGNSKESLKPYKKFVGLNFNAVKAVHRTSDLRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVZ7</accession>
    <name>D0YVZ7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADPH:quinone reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001302</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297835.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001302"/>
    <dbReference type="EnsemblBacteria" id="EEZ40277">
        <property type="protein sequence ID" value="EEZ40277"/>
        <property type="gene ID" value="VDA_001302"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0604">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1752728at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="13"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="317" mass="33657" checksum="8DBC6554FBDAE897" modified="2010-01-19" version="1">MSTYQQVVISQFGGVDVLQCQLTELPTVLEPHQVLVKVDYCAVNPIDAKIRQGSNFVAQQIQNALPWGLGYDIAGKVVSVGSTISALKTGQRVAGLIGFPLQGGGYSQYCVVDWQALSVLPEQVDLRQAAAVPLAGLTAMQAIELADIQPQERVLVLAGSGGVGHLALQLLKVLPCQVLATGSSTNQAFIASLGAKAIDYDKVDFVSLEPVDVIIDLVGGKTGLAALAALKPSGRIITVPTVTQAEIIAQAQDLGFYAQGMVVQPSKIQQDMLLQLIAEKKLRVHIDQQFDFSSVAQAHQHIESGRTRGKLVLATLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW07</accession>
    <name>D0YW07_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 13 15">tRNA (guanine-N(1)-)-methyltransferase</fullName>
            <ecNumber evidence="6 13 15">2.1.1.228</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">M1G-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">tRNA [GM37] methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">trmD</name>
        <name evidence="17" type="ORF">VDA_001312</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 13 15">Specifically methylates guanosine-37 in various tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13 15">
            <text>guanosine(37) in tRNA + S-adenosyl-L-methionine = H(+) + N(1)-methylguanosine(37) in tRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:36899"/>
            <dbReference type="Rhea" id="RHEA-COMP:10145"/>
            <dbReference type="Rhea" id="RHEA-COMP:10147"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73542"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="EC" id="2.1.1.228"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5 13 15">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 13 15">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13 15">Belongs to the RNA methyltransferase TrmD family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.228" evidence="6 13 15"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297848.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001312"/>
    <dbReference type="EnsemblBacteria" id="EEZ40287">
        <property type="protein sequence ID" value="EEZ40287"/>
        <property type="gene ID" value="VDA_001312"/>
    </dbReference>
    <dbReference type="GeneID" id="57339796"/>
    <dbReference type="eggNOG" id="COG0336">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="525632at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052906">
        <property type="term" value="F:tRNA (guanine(37)-N(1))-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18080">
        <property type="entry name" value="TrmD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1270.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00605">
        <property type="entry name" value="TrmD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002649">
        <property type="entry name" value="tRNA_m1G_MeTrfase_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023148">
        <property type="entry name" value="tRNA_m1G_MeTrfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016009">
        <property type="entry name" value="tRNA_MeTrfase_TRMD/TRM10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46417">
        <property type="entry name" value="PTHR46417"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01746">
        <property type="entry name" value="tRNA_m1G_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000386">
        <property type="entry name" value="tRNA_mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00088">
        <property type="entry name" value="trmD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13 15" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 13 15" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 13 14" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="10 13 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="12 13 15" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="tRNA_m1G_MT" evidence="16">
        <location>
            <begin position="23"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="13 14">
        <location>
            <begin position="133"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00014679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR000386-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU003464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF01746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EEZ40287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="248" mass="27775" checksum="B848AFA86108257F" modified="2010-01-19" version="1">MWVGVISLFPEMFDSITNFGVTGQAVKKGLLTVETWNPRDFTLDKHRTVDDRPYGGGPGMLMMVQPLRDAIHTAKQSAKGKAKVIYLSPQGRKLDQAGVEELAQNENLILICGRYEGVDERIIQQEVDEEWSIGDFVLTGGELPAMTLVDAVVRFVPGVLGDFASAEEDSFANGLLDCPHYTRPEVLDGQTVPQVLLSGNHKDISRWRLKQSLGRTWLRRPELLENLALTDDQEFLLAEFIREYKASN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW16</accession>
    <name>D0YW16_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA pseudouridine synthase D</fullName>
            <ecNumber evidence="4">5.4.99.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">tRNA pseudouridine(13) synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA pseudouridylate synthase D</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA-uridine isomerase D</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">truD</name>
        <name evidence="6" type="ORF">VDA_001276</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>uridine(13) in tRNA = pseudouridine(13) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:42540"/>
            <dbReference type="Rhea" id="RHEA-COMP:10105"/>
            <dbReference type="Rhea" id="RHEA-COMP:10106"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="EC" id="5.4.99.27"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the pseudouridine synthase TruD family.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.27" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297768.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001276"/>
    <dbReference type="EnsemblBacteria" id="EEZ40254">
        <property type="protein sequence ID" value="EEZ40254"/>
        <property type="gene ID" value="VDA_001276"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106029">
        <property type="term" value="F:tRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031119">
        <property type="term" value="P:tRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01082">
        <property type="entry name" value="TruD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001656">
        <property type="entry name" value="PsdUridine_synth_TruD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020119">
        <property type="entry name" value="PsdUridine_synth_TruD_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011760">
        <property type="entry name" value="PsdUridine_synth_TruD_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042214">
        <property type="entry name" value="TruD_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043165">
        <property type="entry name" value="TruD_insert_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01142">
        <property type="entry name" value="TruD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00094">
        <property type="entry name" value="tRNA_TruD_broad"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50984">
        <property type="entry name" value="TRUD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01268">
        <property type="entry name" value="UPF0024"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TRUD" evidence="5">
        <location>
            <begin position="158"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="351" mass="39459" checksum="1C20E1041E0A6D86" modified="2010-01-19" version="1">MADIMDSFAYLYGKPEAKGLLKAQDSDFEVVEQLGYDFAGHGEHFMVLIRKSGENTKYVVNELAKACGVKSRDVSWAGLKDRHAVTEQWLSVQLPGKSDPDLTDFVAEHPGIEVLATARHDKKLRPGDLQGNRFTLRITELENCDELNARLEQIAQGGVPNYFGEQRFGHNGNNVVKARAWGNDEFRVRDKSKRSFYLSAARSWMFNQVLSQRIEQGKVSQLMLGDCLLAANDSRPMVVTEITPELEQQVASGELAISAPLLGDNELPTKADAQAFELAIVEQEPALVKLVRDNRMRHERRELLLVPEQMTWQFDENTLTLSFSLPAGAFATAVVRELLDAREPEREFSHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW64</accession>
    <name>D0YW64_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001349</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297898.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001349"/>
    <dbReference type="EnsemblBacteria" id="EEZ40324">
        <property type="protein sequence ID" value="EEZ40324"/>
        <property type="gene ID" value="VDA_001349"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2199">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2909">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="535875at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018683" evidence="1">
        <location>
            <begin position="23"/>
            <end position="758"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="758" mass="87591" checksum="508222217720F05D" modified="2010-01-19" version="1">MKLRRWVLTGLLLSSLSFSTQAKLYSTPILGEASDLLQTNPEQSLVITKRYLSQRRLSEPSEQSRVHTNNEVDHTIRTPLNTINAIQIEAQAYSELNQPQKAISRIKEAEKMAEKNGLTYSVFESRLLQAKFYWVNLRNSAIALKMLDGIDQDISHSEQLKMTKQVKYLQYESLMQRAIIESQLGDDDKATKLFLKAKRYLVSIDDQVELINYQLTVGQHYLLHHHYDLALDRLLSGYWLAVEKENSAKIALANYHLALLFEERKVYDKALEHATQAGDFFERYKRSQMLAKTLTLIASIYEKEGRYNLALVHYFNALDQENQMLHYTRSARLRLNIARVYLHLYNYDKADQYLTQARKLAQQTGNETILAESQIIQGQLDLAEGNSDQAITHLQSGLIAASRIGKVNLQLDGESLLSEAFEKQNDYYNALLSQRRYEQLFAAQQKSQVRSNVEVFKQQQRMLERSLRLEEMERQQFESQTALYKQQKVSLAMLALFIFTLLLLARRHKISKQLQSRLTRLRSEFYTHPRSGLRNLRMLNARLPNSLQQSSANFEQWHLGEIINEPLSDRLRFALFEVPFLKHIYLERGYQFGLEIERKFGDYLQQQVCEPARVYHFSDAMFLYIEPNSRLNGEPNSLADSIQQLVDEFAQQHGLDNSIRIGMAEYPFLPRAYTAINDQELIDILLMATNTARLNSKLQPGSQWVHLSAIDAAPAASFACDNIRIACIQAIKNGLVKVQTSYVGEIKWNADHELESKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW73</accession>
    <name>D0YW73_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">30S ribosomal protein S2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpsB</name>
        <name evidence="7" type="ORF">VDA_001358</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uS2 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297915.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001358"/>
    <dbReference type="EnsemblBacteria" id="EEZ40333">
        <property type="protein sequence ID" value="EEZ40333"/>
        <property type="gene ID" value="VDA_001358"/>
    </dbReference>
    <dbReference type="GeneID" id="57339733"/>
    <dbReference type="eggNOG" id="COG0052">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1623045at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01425">
        <property type="entry name" value="RPS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00291_B">
        <property type="entry name" value="Ribosomal_S2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001865">
        <property type="entry name" value="Ribosomal_S2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005706">
        <property type="entry name" value="Ribosomal_S2_bac/mit/plastid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018130">
        <property type="entry name" value="Ribosomal_S2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023591">
        <property type="entry name" value="Ribosomal_S2_flav_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12534">
        <property type="entry name" value="PTHR12534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00318">
        <property type="entry name" value="Ribosomal_S2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00395">
        <property type="entry name" value="RIBOSOMALS2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52313">
        <property type="entry name" value="SSF52313"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01011">
        <property type="entry name" value="rpsB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00962">
        <property type="entry name" value="RIBOSOMAL_S2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00963">
        <property type="entry name" value="RIBOSOMAL_S2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="241" mass="26646" checksum="31635017F95E789A" modified="2010-01-19" version="1">MATVSMRDMLKAGVHFGHQTRYWNPKMKPFIFGARNRVHIINLEKTVPMFNEALAEINKIAARKGKVLFVGTKRAASEAVKEAAINCDQYYVNNRWLGGMLTNYKTVRQSIKRLKDLETQSTDGTFDKLTKKEALMRTREMEKLEKSLGGIKNMGGLPDAIFVVGADCEHIAIKEANNLGIPVFAVVDTNADPDGVDFVIPGNDDAIRAIQLYTGAVAQAVNEGRNQDIVAQAEDGFVEAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWK8</accession>
    <name>D0YWK8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Membrane protein involved in the export of O-antigen teichoic acid lipoteichoic acids</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_001499</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298163.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001499"/>
    <dbReference type="EnsemblBacteria" id="EEZ40473">
        <property type="protein sequence ID" value="EEZ40473"/>
        <property type="gene ID" value="VDA_001499"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2244">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="564091at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002797">
        <property type="entry name" value="Polysacc_synth"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01943">
        <property type="entry name" value="Polysacc_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="40"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="110"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="166"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="209"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="249"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="286"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="321"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="353"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="376"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="412" mass="46959" checksum="9346D97F8D4BAAE4" modified="2010-01-19" version="1">MNMLKNIIMLFFSQGVNYLVPIILVPYLVRVLGPIEYGKFNLALSIILYGCLFIDFGFNLYSSGKIAKASNKEEINKTYTTTIITKLILFIPISIVIMAIPLFFEKFYDLKALLSILIIQLFSSVISTIWLYQGIEKVRIYSYVNIVIKLTSVPLIFLFVKTKFDLDILAIIQASTFFMSALILLFIAHKENIQFVKIKITDIFYQLKHASPIFLGTISVSLYTMSTPIILGIMSTAFEVGQYTATDKIRGAFISMFLILSNVIYPRVNKLRIESETSALQFIKKVLYIQTSIGIIFSLIIYITSSFIVNHYLGLEFKQSILLLKIMSPMVILVPLSVLLSNYLLLSWEYKRYYLTVPIITCICHFIYVIPLSHSYGAIGSGLSILITELISFSLLTFFVYKSGLMKKLYES</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWP7</accession>
    <name>D0YWP7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">4-diphosphocytidyl-2-C-methyl-D-erythritol kinase</fullName>
            <shortName evidence="9">CMK</shortName>
            <ecNumber evidence="2 9">2.7.1.148</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ispE</name>
        <name evidence="12" type="ORF">VDA_001443</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>4-CDP-2-C-methyl-D-erythritol + ATP = 4-CDP-2-C-methyl-D-erythritol 2-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18437"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57823"/>
            <dbReference type="ChEBI" id="CHEBI:57919"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.148"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="9">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 3/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the GHMP kinase family. IspE subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.148" evidence="2 9"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001443"/>
    <dbReference type="EnsemblBacteria" id="EEZ40417">
        <property type="protein sequence ID" value="EEZ40417"/>
        <property type="gene ID" value="VDA_001443"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1947">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00094"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050515">
        <property type="term" value="F:4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00061">
        <property type="entry name" value="IspE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013750">
        <property type="entry name" value="GHMP_kinase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004424">
        <property type="entry name" value="IspE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43527:SF2">
        <property type="entry name" value="PTHR43527:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08544">
        <property type="entry name" value="GHMP_kinases_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF010376">
        <property type="entry name" value="IspE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="SSF55060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00154">
        <property type="entry name" value="ispE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="5 9 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GHMP_kinases_N" evidence="10">
        <location>
            <begin position="95"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="GHMP_kinases_C" evidence="11">
        <location>
            <begin position="208"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="20"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="145"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="103"/>
            <end position="113"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ40417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="293" mass="32154" checksum="6BB4B61ABE2B2ED6" modified="2010-01-19" version="1">MSHPMNTFFDTTTQWPAPAKLNLFLYITGRRPNGYHDLQTLFQFLDYGDTLTITPRRDSAINLSPAIEGVKTEDNLIYRAADTLRKKANVSLGADIAIEKILPMGGGLGGGSSNAATTLVALNHLWQTHLTTDELAEIGLGLGADVPVFVRGMSAFAEGVGEKLQSAEPEEKWFLVAKPDVSIATVDIFTHPELKRDSKKRPLNALLAGVYENDCEKIVRTLYPEVDKALSWLLEYAPSRLTGTGACVFAEFQTEQEAKSILSKLPNWLHGFVAKGVNTSPLMHTLTTHSLEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWS9</accession>
    <name>D0YWS9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0304 protein VDA_001474</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001474</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0304 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298125.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001474"/>
    <dbReference type="EnsemblBacteria" id="EEZ40448">
        <property type="protein sequence ID" value="EEZ40448"/>
        <property type="gene ID" value="VDA_001474"/>
    </dbReference>
    <dbReference type="GeneID" id="57339559"/>
    <dbReference type="eggNOG" id="COG3013">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1282367at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.680">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00762">
        <property type="entry name" value="UPF0304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005587">
        <property type="entry name" value="UPF0304_YfbU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023146">
        <property type="entry name" value="YfbU_alpha-helical_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023145">
        <property type="entry name" value="YfbU_helix-hairpin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03887">
        <property type="entry name" value="YfbU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006272">
        <property type="entry name" value="UCP006272"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="166" mass="19842" checksum="5EC788A175B66A5F" modified="2010-01-19" version="1">MEMTNAQRLILSNQYTLMAQMDPDNAAKYHRLQTIVERGYALQMRELNKDFGELSEEECRRVIDFMEMYHALQESYKMLDAAHQQQVDHRRLQFLGFDAASEAQLVHYVRFLTDEEGLYPQFDKAEHHFNSQVPMLEKYKRMLQTWRNCPRQYHLSASEIQQIFSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWT0</accession>
    <name>D0YWT0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Formate--tetrahydrofolate ligase</fullName>
            <ecNumber evidence="6">6.3.4.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Formyltetrahydrofolate synthetase</fullName>
            <shortName evidence="6">FHS</shortName>
            <shortName evidence="6">FTHFS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">fhs</name>
        <name evidence="7" type="ORF">VDA_001475</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>(6S)-5,6,7,8-tetrahydrofolate + ATP + formate = (6S)-10-formyltetrahydrofolate + ADP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20221"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 6">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the formate--tetrahydrofolate ligase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.3" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298126.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001475"/>
    <dbReference type="EnsemblBacteria" id="EEZ40449">
        <property type="protein sequence ID" value="EEZ40449"/>
        <property type="gene ID" value="VDA_001475"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2759">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="177859at2"/>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004329">
        <property type="term" value="F:formate-tetrahydrofolate ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00477">
        <property type="entry name" value="FTHFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01543">
        <property type="entry name" value="FTHFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000559">
        <property type="entry name" value="Formate_THF_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020628">
        <property type="entry name" value="Formate_THF_ligase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01268">
        <property type="entry name" value="FTHFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00721">
        <property type="entry name" value="FTHFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00722">
        <property type="entry name" value="FTHFS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 6" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="65"/>
            <end position="72"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="584" mass="62038" checksum="974F65FE7DE449C8" modified="2010-01-19" version="1">MKSDIQICRETILTPIDLIAQQAGIEPQDLTPQGTLKAKVKPAILNRLANKPEGKLVLVTAITPTPLGEGKTVTTIGLAQGLAKINQSVIACIRQPSMGPVFGVKGGAAGGGYSQVAPMEKLNLHLTGDIHAVTAAHNLAAAALDARLYHEQRLGYDLFSEKTGLPALRIDIVRIVWKRVMDHNDRALRMITIGQNEPGKDINGIERHDGFDISAASELMAILALSNDLADMRARIGKIVLAYDLDGNPVTAEDLQVAGAMAVTMCEAIEPTLMQTLEGVPTLIHAGPFANIAHGNSSIIADKIGLKLADFVVTEGGFGSDMGFEKACNIKAQQAKRGPDCAVVVATLRGLKANSGLYDLRPGQPLPDAIFAPDNKALTAGFDNLRWHINNAAKYGVPVVVAINRFPQDSDEELSQLKEMILNTEFNVHVDVALSEAFAKGGDGAIELAHAVVKACQTPANFAPLYCLEQSLEEKLMCVAEVGYGAQAIELSDLAKQQLAQFKAQGFDNLAVCMAKTPLSITTDPAIKGAPTDFVVPVRELKLCAGAGFVYALCGNVMTMPGLPEKPAYMNLDLDADGNIVGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWU5</accession>
    <name>D0YWU5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta</fullName>
            <shortName evidence="13">ACCase subunit beta</shortName>
            <shortName evidence="13">Acetyl-CoA carboxylase carboxyltransferase subunit beta</shortName>
            <ecNumber evidence="13">2.1.3.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">accD</name>
        <name evidence="15" type="ORF">VDA_001537</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 13">Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>acetyl-CoA + N(6)-carboxybiotinyl-L-lysyl-[protein] = malonyl-CoA + N(6)-biotinyl-L-lysyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:54728"/>
            <dbReference type="Rhea" id="RHEA-COMP:10505"/>
            <dbReference type="Rhea" id="RHEA-COMP:10506"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:83144"/>
            <dbReference type="ChEBI" id="CHEBI:83145"/>
            <dbReference type="EC" id="2.1.3.15"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="13">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="13">Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the AccD/PCCB family.</text>
    </comment>
    <dbReference type="EC" id="2.1.3.15" evidence="13"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298236.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001537"/>
    <dbReference type="EnsemblBacteria" id="EEZ40511">
        <property type="protein sequence ID" value="EEZ40511"/>
        <property type="gene ID" value="VDA_001537"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0777">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="504557at2"/>
    <dbReference type="UniPathway" id="UPA00655">
        <property type="reaction ID" value="UER00711"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009317">
        <property type="term" value="C:acetyl-CoA carboxylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003989">
        <property type="term" value="F:acetyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016743">
        <property type="term" value="F:carboxyl- or carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001295">
        <property type="term" value="P:malonyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01395">
        <property type="entry name" value="AcetylCoA_CT_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034733">
        <property type="entry name" value="AcCoA_carboxyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000438">
        <property type="entry name" value="Acetyl_CoA_COase_Trfase_b_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011762">
        <property type="entry name" value="COA_CT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041010">
        <property type="entry name" value="Znf-ACC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01039">
        <property type="entry name" value="Carboxyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17848">
        <property type="entry name" value="zf-ACC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01070">
        <property type="entry name" value="ACCCTRFRASEB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00515">
        <property type="entry name" value="accD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50980">
        <property type="entry name" value="COA_CT_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11 13" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="7 13" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="15" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 13" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="10 13" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 13 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 13" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 13" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CoA carboxyltransferase N-terminal" evidence="14">
        <location>
            <begin position="25"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="13">
        <location>
            <begin position="29"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="29"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEZ40511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="310" mass="34194" checksum="D95AD066515FBC70" modified="2010-01-19" version="1">MSWLEKILTKSNIVTSRKASIPEGVWTKCTSCEQVLYHADLERNLEVCPKCNHHMRMKARRRLETFLDAESQVEIAAELEPMDKLKFRDSKKYKDRLSAAQKNSGEKDALIVMKGTVHNLPIVASAFEFSFMGGSMGSVVGAKFVRAVDEAIANNCALICFSASGGARMQEALMSLMQMAKTSAALERLSAKGLPFISVLTDPTMGGVSASLAMLGDINIGEPKALIGFAGQRVIEQTVREKLPEGFQRSEFLLEHGAIDMIVDRREMRERVAGLVAKLTNQPALDSQNHQPELTAEEEAVIKEDEQTAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX06</accession>
    <name>D0YX06_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phage protein D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002063</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299319.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002063"/>
    <dbReference type="EnsemblBacteria" id="EEZ41031">
        <property type="protein sequence ID" value="EEZ41031"/>
        <property type="gene ID" value="VDA_002063"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3500">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1278199at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="324" mass="35920" checksum="B21A31C6625EA0A1" modified="2010-01-19" version="1">MFHLIGKNAELILERLKSWRLNDGNGTEGDNVTLVISSDDIDGIPPKGERYSVRLGHVVRDEFQISKRSVNLSPREITLVLTVAPFSIMDESGYRERKSSSWDRTTLGQVVFDCVTPHGFDVFVHPRLQKIEIEHLDRSDESTPAFMNRLAKSYDAVAKPVEGKFIFVPIGEQRSASGKDIESVTLSLPAINHSGNSDFINVSAELDGRQEFSGVRAFYGSTDTGKRLEVRVGSKPFKTLGKDKNSKQEAEQACAAELRKMQRQGRKISIEAPPVPTAFAEGIIVLDDSFPRAFKGRCSIDQVSFSGQGLQISRMNIQATLMGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX20</accession>
    <name>D0YX20_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Thiol-disulfide isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001897</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298893.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001897"/>
    <dbReference type="EnsemblBacteria" id="EEZ40865">
        <property type="protein sequence ID" value="EEZ40865"/>
        <property type="gene ID" value="VDA_001897"/>
    </dbReference>
    <dbReference type="GeneID" id="57341980"/>
    <dbReference type="eggNOG" id="COG1651">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1805428at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03019">
        <property type="entry name" value="DsbA_DsbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023205">
        <property type="entry name" value="DsbA/DsbL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13462">
        <property type="entry name" value="Thioredoxin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="1" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018694" evidence="2">
        <location>
            <begin position="18"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin-like_fold" evidence="3">
        <location>
            <begin position="46"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="208" mass="23378" checksum="EA699126F543841D" modified="2010-01-19" version="1">MKLILRSFFSFLFLALALTGCSDSNTPKDGDQYMTIAKPISDMQGVYEVFSLSCGHCRSMETMLPEIKKLAGVKDIRSVHVTFNESAQLAAFVYYAAAIQSPNGEPSDKLTEQLFAYTQDTPKDTPMDKRKEMLNNLFAQYKMNSPYQLTQTQQEEVFSKMDQAQKIIEAANITSVPTFIVNGKYLVNTPAHKSLQDLANTIKYLEAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX23</accession>
    <name>D0YX23_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative heat shock protein YegD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001898</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298895.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001898"/>
    <dbReference type="EnsemblBacteria" id="EEZ40866">
        <property type="protein sequence ID" value="EEZ40866"/>
        <property type="gene ID" value="VDA_001898"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0443">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="410781at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10231">
        <property type="entry name" value="YegD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042054">
        <property type="entry name" value="YegD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="PTHR19375"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0346">Stress response</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="450" mass="50105" checksum="BDE67C71600FF6C4" modified="2010-01-19" version="1">MFIGFDYGTANCSVAVMENGQPKLLPLEQDNPYIPSTLAAPTREAVSEYLYRFMGVKPLDSVGEQVLRRAVAFNREEDIIVEQGDLLFGQAALDSYLADPEETYYVKSPKSFLGANGLRDVQISFFEDLVCAMMKNIKLQAELSMQQDIVNTVIGRPVNFQGTGGESANLQAEKILLQAAKRAGFKEVEFQFEPVAAGLEYESSLTEDKTVLVVDIGGGTTDCSLIQMGPTWRQQADRSASLLAHSGQRIGGNDLDIYLAFKQLMPQFGYGSKTLRGIEMPLSQFWNPIAINNVAAQTEFYSNANLRALDQLRRDAQEPEKLQRLIHVYHETLGYQLVRRAEEAKIALSEQQAYQVHMQILADQFQIDINQQQLAEAIDVPKEKMRELVVEALAQADTQPDVIFMTGGTARSPILRQCIEQQLPNIPIVSGSYFGSVTSGLARWADHCFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX24</accession>
    <name>D0YX24_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001899</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298897.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001899"/>
    <dbReference type="EnsemblBacteria" id="EEZ40867">
        <property type="protein sequence ID" value="EEZ40867"/>
        <property type="gene ID" value="VDA_001899"/>
    </dbReference>
    <dbReference type="GeneID" id="57341977"/>
    <dbReference type="eggNOG" id="COG0546">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1484726at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="211" mass="24146" checksum="461D67A0EAA09797" modified="2010-01-19" version="1">MKLFILDIDGLLIDEDQFDRECYIKAINQELNIQVTADELCKLNVTDASALDHFIECYQIKESRSVLHRQVEKTYYQLLRQALIERNYSDQDKAKVHNLFSELKARKDLHLAVVSSHWGSIAKLKLWAMGIELNRLTFASASDALHFVDVVALASFRAKQDAGELFAERLLISDAEAACKIAKELKDTWLSYEQAAALDINIAYVREYEMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX27</accession>
    <name>D0YX27_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Hypothetical transcription regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001902</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298903.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001902"/>
    <dbReference type="EnsemblBacteria" id="EEZ40870">
        <property type="protein sequence ID" value="EEZ40870"/>
        <property type="gene ID" value="VDA_001902"/>
    </dbReference>
    <dbReference type="GeneID" id="57341973"/>
    <dbReference type="eggNOG" id="COG2207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020449">
        <property type="entry name" value="Tscrpt_reg_HTH_AraC-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00032">
        <property type="entry name" value="HTHARAC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="HTH araC/xylS-type" evidence="3">
        <location>
            <begin position="131"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="234" mass="26690" checksum="AA0F223A86462256" modified="2010-01-19" version="1">MIWVNCTHSDKHCEAKENLRQLHNFKDVSPFELLASMTGKELVFLEIKDSSSDGFTLLKAIRNRYPSTKVIVVYHKLDSELALNVLRAGGEDILPASSNRQQLESCFTRLHTHDVEDEITQDISEREEPLRPALKIIDENLSSPLREEDLAAACHYSPTYFSRLFHSVMGVTLKQYIIKKRLDMACGLLSADKEKIAVIALTTGFKDVSYFSRVFKKHLGCSPGEFRTRKQRLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX63</accession>
    <name>D0YX63_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PapD_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001852</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298817.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001852"/>
    <dbReference type="EnsemblBacteria" id="EEZ40820">
        <property type="protein sequence ID" value="EEZ40820"/>
        <property type="gene ID" value="VDA_001852"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3121">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008962">
        <property type="entry name" value="PapD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016147">
        <property type="entry name" value="Pili_assmbl_chaperone_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00345">
        <property type="entry name" value="PapD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49354">
        <property type="entry name" value="SSF49354"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PapD_N" evidence="1">
        <location>
            <begin position="29"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="220" mass="24984" checksum="AA2AEE728CE6EB8C" modified="2010-01-19" version="1">MKMFLLFFALFSSYVLGLEISPMVQEWNLSESQRNKMISLYNDSNQRVAIEVIPSNINQDKNDINHKLQVFPPAFLIEPGKRQNVMLVWSDNTVLKSSLSYFVSFIQHPTAKDSDAGIQIRIRYNAVVHITSNNLLDSVNVVSVENTTTGLKAEIINSGNKYTRLEDYQISLIDLQGKAFTVTSSQISPNSLFLYPQQKKSLFIDTSGRKVRSIELIKDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX64</accession>
    <name>D0YX64_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001853</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298819.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001853"/>
    <dbReference type="EnsemblBacteria" id="EEZ40821">
        <property type="protein sequence ID" value="EEZ40821"/>
        <property type="gene ID" value="VDA_001853"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3188">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="120032at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015473">
        <property type="term" value="F:fimbrial usher porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009297">
        <property type="term" value="P:pilus assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2610">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000015">
        <property type="entry name" value="Fimb_usher"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042186">
        <property type="entry name" value="FimD_plug_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30451">
        <property type="entry name" value="PTHR30451"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00577">
        <property type="entry name" value="Usher"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019859" evidence="1">
        <location>
            <begin position="21"/>
            <end position="832"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="832" mass="92761" checksum="8D6646E00BF29CD9" modified="2010-01-19" version="1">MRILISIYILLCLLVLPAGAAKFNPTSQPLELQTLLTMNGHALGSVLITIDTDDSISLDSKQTLELLSQSLSGDIINQLKGESKQGRLTPDDFKRKGVELVFNPELFEMQLTMQKAQQKEHALSAIMKQPNRKYQADAKLSGYLNSRAALVHDEYKNQQASDSNITQYYQFETGVRWKKNFLTSEFTLDDEDGGNWQFKRIGTRLSRDFADSATRITLGDFYQTSVGFQDSTDIIGLSISRDYSDIPTRNVRPTASQRFTLQRTSNVDVKVDGIIVNRLTLAPGSYNLQDIPLAAGNNNVELVISDNYGNSETLNFNIATGRDLLKEGEFEYSLGFGVPGNLSNQGMEYENQHRVISGFYEYGLNPWLTLGVNGQWLISRDSNKKTDIQQLGQRTLVATSIGTFETNVAYSDHDYYHSGWAASIGFDAEFPARDQFNPSLSIKYEYFSPNFVGINDVTSDAETYESNGSLDFSALQSDQHAVTLYFDSNITSTLRGSLSGVYSYSYDNDYRWSISSGLSAPLFSTAATWNVTATYQYEKRTDDDLSLQAIVSWPLGYTGRWISNYNSYNQQAQSELSYQKNLGNTGGISTFIGVENSKDTDAAIDAGFYYTGNRFEFNADHTTRYVDLSDTDRSHVSRVELATSVAFADGQWAVGRPVNESFAIIKSHANLKEHYIEIQPNDDTARVNSDNLGAMLIPDLVAYSEQQINYDVEDLPPGYSLGEGSFALYPENGSGYALTIGSDDVITVMGAFENPNKQPLSLAVGSATLRNNTQYVPIEFFTNRNGKFAISGLREGHYSIRFAKHNLYYDLHIKENSPLLINLGTISLNKQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX71</accession>
    <name>D0YX71_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator AraC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001834</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001834"/>
    <dbReference type="EnsemblBacteria" id="EEZ40802">
        <property type="protein sequence ID" value="EEZ40802"/>
        <property type="gene ID" value="VDA_001834"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020449">
        <property type="entry name" value="Tscrpt_reg_HTH_AraC-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00032">
        <property type="entry name" value="HTHARAC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="2">
        <location>
            <begin position="200"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="321" mass="36595" checksum="F81A3E1A8BCB3246" modified="2010-01-19" version="1">MIFDWCCVHEYQQQPHGGLIFITTRSSFGMKYKRILSQSHIVLKEFYVDHHLIVNLKNGDGDVCINGQSVTISSNATLVIPKFSHISCTINQKDCHKNIELQLLMVGEETIAQSFKYMASLKQPNTPTANCMPVYHLNETPDVVEQNFQLFQQSLPAVADTRLEKTFLTQSLFFILLALNEAGIDVFNVYRFNYDEPKERTIARLITQDPQRKWSVDDMAKALFTTQSTLRRHLAKEGVSFSQLLLDVRMGLALNYLTFSNYSISQIGHRSGFGSAAYFCDAFKRKYGITPSQFRATSREHNDMSALHQLTPKAEMTIDVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX74</accession>
    <name>D0YX74_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">L-serine dehydratase</fullName>
            <ecNumber evidence="9">4.3.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">VDA_001835</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>L-serine = NH4(+) + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:19169"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="EC" id="4.3.1.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 9">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the iron-sulfur dependent L-serine dehydratase family.</text>
    </comment>
    <dbReference type="EC" id="4.3.1.17" evidence="9"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001835"/>
    <dbReference type="EnsemblBacteria" id="EEZ40803">
        <property type="protein sequence ID" value="EEZ40803"/>
        <property type="gene ID" value="VDA_001835"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1760">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003941">
        <property type="term" value="F:L-serine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029009">
        <property type="entry name" value="ASB_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004644">
        <property type="entry name" value="Fe-S_L-Ser_mono"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005130">
        <property type="entry name" value="Ser_deHydtase-like_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005131">
        <property type="entry name" value="Ser_deHydtase_bsu"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03313">
        <property type="entry name" value="SDH_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03315">
        <property type="entry name" value="SDH_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143548">
        <property type="entry name" value="SSF143548"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00720">
        <property type="entry name" value="sda_mono"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="9" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="6 9" id="KW-0408">Iron</keyword>
    <keyword evidence="7 9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8 9 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SDH_beta" evidence="11">
        <location>
            <begin position="1"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="SDH_alpha" evidence="10">
        <location>
            <begin position="162"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU366059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ40803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="431" mass="46660" checksum="4A41EF107DA2D0FB" modified="2010-01-19" version="1">MKAGKEFIDDLRAMGKLRDITKITVDVYGSLSLTGKGHHTDIAIIMGLAGNSPEHVDIDSIPGFIARVEETERLPVGMHCHTVEFPRDGGMNFHTTNLPLHENGMTIRAWIGEEEAYTKTYYSIGGGFIVDEENFGKEQSSTVQVPYMYTTAEELLAQCKESGLSISSLVMANERAMNAEDEISTYFANIWRTMRECMERGMTEEGILPGPLRVPRRAAALRQQLITTEKLSNDPMTVVDWVNMFAFAVNEENAAGGRVVTAPTNGACGIIPAVLAYYDKFIQSVGPKEYTRYFAASGAVGGLYKRNASISGAEVGCQGEVGVACSMAAAGLAELMGGSPEQVCMAAEIAMEHNLGLTCDPVAGQVQVPCIERNGIAAVKAINACRMALRRSSDPRVSLDKVIETMLETGKDMNAKYRETSQGGLAIKVIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXT7</accession>
    <name>D0YXT7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Type cbb3 cytochrome oxidase biogenesis protein CcoI</fullName>
            <ecNumber evidence="8">3.6.3.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_002100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.4" evidence="8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299433.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002100"/>
    <dbReference type="EnsemblBacteria" id="EEZ41068">
        <property type="protein sequence ID" value="EEZ41068"/>
        <property type="gene ID" value="VDA_002100"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2217">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="237367at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021993">
        <property type="entry name" value="ATPase-cat-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027256">
        <property type="entry name" value="P-typ_ATPase_IB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12156">
        <property type="entry name" value="ATPase-cat_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00941">
        <property type="entry name" value="CDATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="SSF55008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01525">
        <property type="entry name" value="ATPase-IB_hvy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="180"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="215"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="249"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="277"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="426"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="453"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="762"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="7">
        <location>
            <begin position="97"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ41068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="806" mass="89063" checksum="C66A1416ACCFFDB0" modified="2010-01-19" version="1">MTTFNYDDTHCYHCGEDIPPHSHFQVDILGSSRAMCCPGCEAVATTIVQSGLSSYYEFRTEPADKAELVPEELQALTLYDNHDIQQDFVHQKGEFKEALLSIEGVSCAACAWLIERQVHKLPGVKSVKVNTTTHRALLCWDENQIKLSEILTPIHQLGYKAAPFEADAHEQQYHRAMKQYLYRLGIAGIATMQVMMLAFALYFEVFGDLSPEFKQYFRWVSLIFSTPVLLYSALPFYLNAWRNLKARTLGMDVPVSIALLFAYFASLYATVMETGEVFFESIAMFTFFLLLGRFLEMRARRQAAAASANLLKLIPAMARLASGEQVAAKKLKKGDVVTVLAGERIPTDGNIVSGKSTVNESMLTGESKPITKELGATVFAGTINGEGILKVKVENEKNESLISQIVRLQDEAQQSKPQIAIVADVVARYFVTAILTIAAFTWLYWHFNQPNDALWITLAVLVATCPCALSLATPTALTCSTSSLSRLGILLRREHVLETLSNVNRLIIDKTGTLTEGNIQITETHLFTERYSMVQIQAYAVGLEFYSSHPIARAFQQEDNQQKIQFDSVENHVGFGLQGHLGNDIWRIGKYAYITELSNHHNSTRSAQCFTNIQHYPVWLSVNGLPIAAFSLSDPIRPSSFELIEHFHNHGIKVTMLTGDHSDNAQSVAQALNIDELISNQTPQGKLNYLKSLPKSDISLMVGDGVNDAPVLAGAHLSLAMGGGTDIAKSSADMVLLGDNLQRLLDARALAQKTQNIIKQNLAWALGYNLIILPLAVCGYVAPYIAVIGMSASSLIVVSNSLRLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXU3</accession>
    <name>D0YXU3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002106</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299449.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002106"/>
    <dbReference type="EnsemblBacteria" id="EEZ41074">
        <property type="protein sequence ID" value="EEZ41074"/>
        <property type="gene ID" value="VDA_002106"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031N45">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2152918at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="251" mass="28491" checksum="6B721FDE25C379F2" modified="2010-01-19" version="1">MSRSLVLTILFILLALFIGYLFLVPDEHKQVQELQPKQIKVPLERFSEDDLDRVIDPPSNFHQLQQVTDTIDQQLSDICVEEPSFEQLEQFGTAKNHQTSTLPQSITIIDQPLWHFHPQLKKTVVSEQQITELPDENYLELDSNLLDALTVGDQLDLALPGGEAQTVIITNVSQPRSDLKIVKLANQQGRNIGNITQFNNTTEGQIRSDDNQEYHLRTTKQRGWIASKKALSQVNDPAVKNNSDPFTDLIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXX4</accession>
    <name>D0YXX4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">VgrG protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002137</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the VgrG protein family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299519.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002137"/>
    <dbReference type="EnsemblBacteria" id="EEZ41105">
        <property type="protein sequence ID" value="EEZ41105"/>
        <property type="gene ID" value="VDA_002137"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3501">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1880900at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006531">
        <property type="entry name" value="Gp5/Vgr_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017847">
        <property type="entry name" value="T6SS_RhsGE_Vgr_subset"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006533">
        <property type="entry name" value="T6SS_Vgr_RhsGE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037026">
        <property type="entry name" value="Vgr_OB-fold_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04717">
        <property type="entry name" value="Phage_base_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01646">
        <property type="entry name" value="vgr_GE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03361">
        <property type="entry name" value="VI_Rhs_Vgr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phage_base_V" evidence="2">
        <location>
            <begin position="383"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="685" mass="76262" checksum="A5D5FFF6DD3CE91A" modified="2010-01-19" version="1">MATGLQFTFTVEGCETSTFAVTEFCGNDGLSLPFSFLIELASREPFIGPDEIVDNNCTLTVWRDGECQQEWHGIVSAFSQGDTGHRHTLYQVEMVPPLARLSLRQNSRIFQTQTVPEIISILLQEMNIQDYAFALARQYPQREYCVQYRESDLEFIQRVAAEEGIFFHFNHNKKNTVIFTDDNQNVEMLADPVTYNALSGGSSPLPFVRQFKQTTQIRPSSAQLKDYSFKNPAYSFLQTFQATESDYQQDIYEHYDYPGRYKDDENGKPFTQFRLESLRRDANIGLGKSNIAKVIPGQKILLQDHSTEECNRDWFVVENNHVGTQPQALEEAGGEGETTYNNEFLVISGHHAWRPPFNAKPRVDGPQIAQVVGPEGEEIYCDEYGRVKVQFPWDRYSNSDDKASCWIRVSQAWAGTQYGMVTIPRVGNEVIVSFLEGDPDQPLITGRTFHATNKPPYELPAHKTRTVLRTETHQGDGYNELRFEDQAGKEEIYVHAQKDVNVLVENDRTDNIKHDLHLDVENERFSHIKANDHLTVDGEARQHTKGNQTLVVDGSLHVKTGQAWISESGNEIHIKAGQKVVIEAGAEITVKAGGSFIKVDDSGVSLVGSAVNLNSGGSAGSGSGYAGSAPLLPGAIEVAPYPLDVPPVFVSALLIASKANIPLLPVCGLQSDGSCQRGDKCLCKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXX8</accession>
    <name>D0YXX8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002141</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299529.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002141"/>
    <dbReference type="EnsemblBacteria" id="EEZ41109">
        <property type="protein sequence ID" value="EEZ41109"/>
        <property type="gene ID" value="VDA_002141"/>
    </dbReference>
    <dbReference type="GeneID" id="57341723"/>
    <dbReference type="eggNOG" id="ENOG50337U9">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1542147at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008769">
        <property type="entry name" value="PhaF_PhaI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05597">
        <property type="entry name" value="Phasin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="118" mass="13214" checksum="29A0202ED097EE80" modified="2010-01-19" version="1">MIDKTVMKAAKSVVESGEGVARNIWLAGLGLYSRSLEEAQQLNEKTNQAFDELVERGKEVETQAKVCISKNAEKATDEMEAGMNDIFYRLSGVDREKLTRMDEKIDKLTQAVEKLTEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY10</accession>
    <name>D0YY10_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF2786 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002173</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299587.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002173"/>
    <dbReference type="EnsemblBacteria" id="EEZ41141">
        <property type="protein sequence ID" value="EEZ41141"/>
        <property type="gene ID" value="VDA_002173"/>
    </dbReference>
    <dbReference type="GeneID" id="57341686"/>
    <dbReference type="eggNOG" id="ENOG5032SJJ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1361517at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024498">
        <property type="entry name" value="DUF2786"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016868">
        <property type="entry name" value="Phage_B3_Orf5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10979">
        <property type="entry name" value="DUF2786"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028111">
        <property type="entry name" value="UCP028111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2786" evidence="2">
        <location>
            <begin position="7"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="232" mass="26285" checksum="1A253291856C8559" modified="2010-01-19" version="1">MSDKKRKALQKIAKCLELGNSANVNEAAQAIRMAHRLMLKYGLEKDDIEFIKMGKTKSATLLPTDISQSILKIIRGINRRFGVECVLTNYKGLKQAEFIGMAERAIFAAFAFDVVYREMNQQTGQFRNSFQGTGTSSSEVNRRVGSFLAGWIEGALEKLPTLTTDDDHDKRMTNYIDREFENLDRETFKQQLQEAMKALTDDYEKGMKKGRSISVNRPVGGASAREELKRLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY42</accession>
    <name>D0YY42_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Hypothetical Glutamate decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_002205</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 3 4">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the group II decarboxylase family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299646.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002205"/>
    <dbReference type="EnsemblBacteria" id="EEZ41173">
        <property type="protein sequence ID" value="EEZ41173"/>
        <property type="gene ID" value="VDA_002205"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0076">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1478871at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016830">
        <property type="term" value="F:carbon-carbon lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022517">
        <property type="entry name" value="Asp_decarboxylase_pyridox"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002129">
        <property type="entry name" value="PyrdxlP-dep_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00282">
        <property type="entry name" value="Pyridoxal_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03799">
        <property type="entry name" value="NOD_PanD_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0456">Lyase</keyword>
    <keyword evidence="3 4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="3">
        <location>
            <position position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR602129-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="549" mass="61632" checksum="6CA9783CB319AB0B" modified="2010-01-19" version="1">MTIEERTADVNLESLHRIFTIPEAPDSTLGKIEQEISQNLNEFLGTHIAAIEKPLAEIEQDFASHDIPEQPSFVSDHTQFLLNKLVAQSVHTSAPSFIGHMTSALPYFLMPLSKIMIGLNQNLVKIETSKAFTPLERQVLGMIHNLIYHQDESFYQQWMHSADHSLGAFCSGGTIANITALWVARNSALKPDGEFKGVAQEGLFKAMKHYGYDDLAILVSERGHYSLKKAADVLGLGRDNLIAIKTDENNRICLDALESTIADLKQRNIKPFAIVGIAGTTETGNIDPLNQLADIAQREQCHFHVDAAWGGASLMSNKYRHLLSGVERADSVTIDAHKQMYVPMGAGMVIFKNPELMASIEHHAEYILRQGSKDLGSHTLEGSRSGMAMLLYASLNIISRPGYELLINNSIEKAQYFADIINQHPDFELVSEPELCLLTYRYVPARTQQALEIATEEEKETLHNALNDLTQFIQKHQRETGRSFVSRTRITPKQWQRRMTTVFRVVLANPLTTNEILQNVLEEQIELAQDSHISLPQIKALTDKILKRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY43</accession>
    <name>D0YY43_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">TorCAD operon transcriptional regulatory protein TorR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_002206</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299648.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002206"/>
    <dbReference type="EnsemblBacteria" id="EEZ41174">
        <property type="protein sequence ID" value="EEZ41174"/>
        <property type="gene ID" value="VDA_002206"/>
    </dbReference>
    <dbReference type="GeneID" id="57341650"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="817710at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="4"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="137"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="137"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="237" mass="27274" checksum="81E8DFBFDB491C1D" modified="2010-01-19" version="1">MSHHVLVVEDEIVTRTKLVGYFENEGYKVSQADSGEQMRDIMATEKVDLVMLDINLPGEDGLMLTRELRSRSEVGIILVTGRTDSIDRIVGLEMGADDYVTKPFELRELLVRVKNLLWRMSLVEKARDETMVEMQEDNIIRFGDWQFDINKRALTHNGLPVKLTKAEYELLVAFSSHPNVVLSRERILNMLSHRVEAPNDRTIDVLIRRMRSKMEIDPKNPQIFVTVHGEGYMFAGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYJ5</accession>
    <name>D0YYJ5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sodium/dicarboxylate symporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_002358</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299949.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002358"/>
    <dbReference type="EnsemblBacteria" id="EEZ41326">
        <property type="protein sequence ID" value="EEZ41326"/>
        <property type="gene ID" value="VDA_002358"/>
    </dbReference>
    <dbReference type="GeneID" id="57341443"/>
    <dbReference type="eggNOG" id="COG1301">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="781228at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001991">
        <property type="entry name" value="Na-dicarboxylate_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036458">
        <property type="entry name" value="Na:dicarbo_symporter_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00375">
        <property type="entry name" value="SDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118215">
        <property type="entry name" value="SSF118215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="38"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="151"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="197"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="228"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="335"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="366"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="417" mass="44021" checksum="B9398759621C77A2" modified="2010-01-19" version="1">MKLKLFKSLPSQLLIAALVAWSMVQVLPISSEFVQSSWFQLIMMFKTTYIGLLKMVVGAVVLLSLLQGITSIGSTVKLKSLGAKTIAFYSLTSILAISLGLGVSLSLPPWPQLIDPNTVALGSNVTLIDSSSSSGGAIVEKLFKMALVNPFQALATTNLLGIVVFALLFGIALLATLPEKHPVFEVINGLNHSLNRLVSAIIKLAPLAVFAIVFEFTLKSGNALFGELARFALLVFTLTLIHGVIVLPSIAKLATGISFKKLFRALSAPMAMAFATSSSSATLPLSMQTAENELDISQSTSSMVLPLGSIMNMDGTALFEGVAAIFLAQLYGIDLGTTGLIMIFIMAMVSSIGAPGMPSGSMSGMQLVMLAAGIPLEAIAILLLIERPLDTFRTAVNVEGDLIAALVVDKWQNKTSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYK3</accession>
    <name>D0YYK3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Signal transduction histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002366</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002366"/>
    <dbReference type="EnsemblBacteria" id="EEZ41334">
        <property type="protein sequence ID" value="EEZ41334"/>
        <property type="gene ID" value="VDA_002366"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0642">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="202"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="390" mass="45028" checksum="BF069B686FF2E2C8" modified="2010-01-19" version="1">MTFVMFALYWGVIYIAENQLEVISLHHWLDTEATRYVMDYQKDQEQAALPNKSEFSTYWSEQPMPKWLDSYNKPGFYEHLLGDEDKHFIVLKHPSGNGLLYLVFQDDADDYLDSYEDNLHYFTFFFGGLITLAMALYGVYFVRTLSKPFATIEEKISQMQPDQPAFSVDSQYSETRHIEQALLDSKNNIAGFFQREKEFSRFASHELRTPIMVIKGSADLLKKVPNQPRVALKAIDRMQQASDEMRILTETFLLLGKEQIDNHYFGEFSLDSALYQQLELLEPLFAKQDSGYQLEIKNPITAYAPESFITIVINNLIKNAFSYSIGDIHISLDAETLTITNRHDGHETYNAGYGCGLVIVERICERMGWQFSATDTGTQFATEIQFHNRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYM9</accession>
    <name>D0YYM9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Anthranilate synthase component 1</fullName>
            <ecNumber evidence="5">4.1.3.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">VDA_002392</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>chorismate + L-glutamine = anthranilate + H(+) + L-glutamate + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:21732"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16567"/>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="4.1.3.27"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="7">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 1/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the anthranilate synthase component I family.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.27" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300015.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002392"/>
    <dbReference type="EnsemblBacteria" id="EEZ41360">
        <property type="protein sequence ID" value="EEZ41360"/>
        <property type="gene ID" value="VDA_002392"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0147">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1786019at2"/>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004049">
        <property type="term" value="F:anthranilate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005801">
        <property type="entry name" value="ADC_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019999">
        <property type="entry name" value="Anth_synth_I-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006805">
        <property type="entry name" value="Anth_synth_I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005257">
        <property type="entry name" value="Anth_synth_I_TrpE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015890">
        <property type="entry name" value="Chorismate_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11236">
        <property type="entry name" value="PTHR11236"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11236:SF22">
        <property type="entry name" value="PTHR11236:SF22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04715">
        <property type="entry name" value="Anth_synt_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00425">
        <property type="entry name" value="Chorismate_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001373">
        <property type="entry name" value="TrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00095">
        <property type="entry name" value="ANTSNTHASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56322">
        <property type="entry name" value="SSF56322"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00565">
        <property type="entry name" value="trpE_proteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="5 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="Anth_synt_I_N" evidence="10">
        <location>
            <begin position="25"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="domain" description="Chorismate_bind" evidence="9">
        <location>
            <begin position="262"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="region of interest" description="Tryptophan binding" evidence="8">
        <location>
            <begin position="311"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Chorismate binding" evidence="8">
        <location>
            <begin position="348"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Chorismate binding" evidence="8">
        <location>
            <begin position="503"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>L-tryptophan</name>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="311"/>
            <end position="313"/>
        </location>
        <ligand>
            <name>L-tryptophan</name>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="348"/>
            <end position="349"/>
        </location>
        <ligand>
            <name>chorismate</name>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="381"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="469"/>
        </location>
        <ligand>
            <name>chorismate</name>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="489"/>
        </location>
        <ligand>
            <name>chorismate</name>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="503"/>
            <end position="505"/>
        </location>
        <ligand>
            <name>chorismate</name>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="518"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR001373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001373-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001373-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001373-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ41360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="552" mass="61205" checksum="8B7AAA2D0183EE6D" modified="2010-01-19" version="1">MTYKDSTPQASAQLEVLALEVPYVADPTELYYALCGQSTNSLLLESAEVDSKQNLKSLMLIDAAVRIVCRGHQVDFEALTLNGENVLASLVDSLDPSLITQQSRKTLTLSYLSHHQDTELDEDSRLRQASNFDALRAVQQLYPTTALPHDALFLAGLFAYDLVAAFEPLPEVDAKTQCPDYVFYVAETLLVMDHQKRKSKLQASLFSHQSSEDSPSDSSHYAHNYHELSRRIQAIKEQCLTKITVPPAPVMTDLAPTTNVSDEQFCQQVNFLKQHVIAGDIFQVVPSRQFTLPCPDPLAAYRALKQGNPSPYMFYLRDQDFTLFGASPESALKYSKATNQVEIYPIAGTRPRGKNRDGSINLDLDGRIELELRCDVKEKAEHMMLVDLARNDVARISEPGSRYVADLLKVDRYSHVMHLVSRVVGQLRSDLDALHAYQACMNMGTLTGAPKIRAMQLIRQVEQQRRGSYGGAVGYLTGTGDMDTCIVIRSAYVENEVATVQAGAGVVYDSIPQAEADETRAKAQAVIRAIQQAHSTSANSLRSQNSKESHNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYP8</accession>
    <name>D0YYP8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_002411</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002411"/>
    <dbReference type="EnsemblBacteria" id="EEZ41379">
        <property type="protein sequence ID" value="EEZ41379"/>
        <property type="gene ID" value="VDA_002411"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0531">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="38"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="73"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="128"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="173"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="247"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="273"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="321" mass="34882" checksum="6D65B0B0BD906153" modified="2010-01-19" version="1">MLLLTMSYILLSGAALLGGVQPADPITVDAMIPEFSWAFLGITTWIFMAAGGAESVAVYVNDVKGGSKSFVKVIIVAGLFIGVLYSVGSVLINVFVSSSELKFTGGSVQVFEGLARYFGLPEIMMNRFVGLVSFTAMFGSLLMWTATPVKIFFSEIPAGIFGKKTVELNENGVPARAAWIQYLIVLPLMVIPALGSNTAQDLMNTVINMTAAASMLPPLFIMLAYLNLRVKLDHVERDFKMGSRRTGIVVVSILIAIFTVGFLASTFPTGADIMTIVFYNVGGIVLFLGFAWWKYGQYEKTLNHEERQQEAPPAELLTENA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYQ1</accession>
    <name>D0YYQ1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transposase IS4 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_002414</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300046.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41382">
        <property type="protein sequence ID" value="EEZ41382"/>
        <property type="gene ID" value="VDA_002414"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3666">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="568762at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025668">
        <property type="entry name" value="Tnp_DDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008490">
        <property type="entry name" value="Transposase_InsH_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13751">
        <property type="entry name" value="DDE_Tnp_1_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05598">
        <property type="entry name" value="DUF772"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF772" evidence="2">
        <location>
            <begin position="55"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="Tnp_DDE_dom" evidence="3">
        <location>
            <begin position="376"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="151"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="509" mass="58096" checksum="B4B1C416AE8ADF46" modified="2010-01-19" version="1">MPNFKTDYSNQYMFVPVIIDEQIIPGTIEYAIAHIVDNHLDLSPFDEHYCNDQNGAAAYPPSIMLKVIFYAYSLGMLSSRRIEKACINNVTFMCLSGDVRPHFTTIAAFIAKMKDTIESLFTQVLMICDEQGLIGRNMFAIDGCKISSNASKEWSGTHDELQRKKEKLERASRRIIERHQNQDALPNEVIAQDLKQKQKLDSSTNKIGEFLASTQDKLGSNNKPIKSNITDNDSAKMTTSKGTIQGYNGIAITDDKHQVILYSQVWGSVGEQQTLKPAVLALNEQLDKLPNSAEHTIKFTADSGFHSKANLKFLAGTPYDCYIADTAFRSRNPLFQSSETYKTEQAKKRKKRSKTGKTCYPITMFEFDQDTMTCRCPAGKMMRLSSKNAVIRGERGAQFCGYLNDCRQCTHQSQCMWKPPGKQQGRQVFFIYKNTKDFDHMQAMKDKIDSPEGRRQYSKRLWCVEPVFGNITVNKQMNRFTLRGKEKVNAQWAMFSLLHNIEKLRNYIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ29</accession>
    <name>D0YZ29_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Inner membrane component of tripartite multidrug resistance system</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_002542</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300290.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002542"/>
    <dbReference type="EnsemblBacteria" id="EEZ41510">
        <property type="protein sequence ID" value="EEZ41510"/>
        <property type="gene ID" value="VDA_002542"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1108236at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004638">
        <property type="entry name" value="EmrB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00711">
        <property type="entry name" value="efflux_EmrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="23"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="62"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="115"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="149"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="176"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="210"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="239"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="277"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="317"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="342"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="367"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="481"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="24"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="512" mass="55969" checksum="9105BED50AD7110C" modified="2010-01-19" version="1">MAEVEIPTGSSAADQMSEKSRSLVTFAVMLSAIMVLLDMTIANVALPHMMGSLGVTSEQITWVLTSYSMAEAIFIPLASYLTLKIGVRKLLLVSISGFIVTSALCGQADSLAEMVTFRVMQGAFGASVIPLSQSIMVQIYPPTQRGKAMALFSVGVLLGPILGPTLGGIITENMDWRWIFYVNLPVGLFCLALLFFFVKIDGRGKSRVDWPIVIAMAIGIGLLQMVLDRGNEEGWFESNLILFSAIISAIAVIFFVVRSFKTKGDIAPVWLLKDRNLAMSCLVMAGFAMGMFGITQLQPMMLEQLLNYPVDTTGLVMAPRGLTSAIVLLMMARYMDRLDARMLIVVGLLLNALGTYLMTQYSMNIDLHWILLPSIIQGAGMGLVFSPLSQLAYATLAKEYTVGGAVVYNLCRTIGGSFGISIVNTYFSRTEQREWHALGGDLTLSNPILQQAAQAQGHSITDPSFMANIQALLHQQSTLLAFVYTFGFILASYLLLIPFIFLFKKKPKPVDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ54</accession>
    <name>D0YZ54_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002567</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300349.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002567"/>
    <dbReference type="EnsemblBacteria" id="EEZ41535">
        <property type="protein sequence ID" value="EEZ41535"/>
        <property type="gene ID" value="VDA_002567"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5662">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1256817at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021806">
        <property type="entry name" value="DUF3379"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11859">
        <property type="entry name" value="DUF3379"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="237" mass="26103" checksum="6CD052DE5C51C890" modified="2010-01-19" version="1">MDDLEFRRRLFADPNDDDPKLQASKNASVTNRKLANDLINLDAQLKQAMDVDVPDDLAEKILFKQAGQPSVKSDRRRWYPALAASVALVVGIFIGRYDITPIAPAQAENLAQIAIKHVDNEAPFIRHVDEGVALQQVNAKLSPFGNTFKALPGHIYYVNHCGFGTMHALHMVMQTEVGKVTVFIVPETSAELETYSNSQVETVVMPIHEASLVIVGDTGQNLMPVADSIRADLQQSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-06-02" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ59</accession>
    <name>D0YZ59_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cytochrome c-type biogenesis protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_002572</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Possible subunit of a heme lyase.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the CcmH/CycL/Ccl2/NrfF family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002572"/>
    <dbReference type="EnsemblBacteria" id="EEZ41540">
        <property type="protein sequence ID" value="EEZ41540"/>
        <property type="gene ID" value="VDA_002572"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3088">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005616">
        <property type="entry name" value="CcmH/CycL/Ccl2/NrfF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038297">
        <property type="entry name" value="CcmH/CycL/NrfF/Ccl2_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03918">
        <property type="entry name" value="CcmH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="147"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="161" mass="18200" checksum="1895F00A498E0BA5" modified="2010-01-19" version="1">MALTIALPALASIDVYDFKNNEQEKQFQELTSTLRCPKCQNNDIADSNATLAQDMRRKVYEMLQQGKSEKEIIDYMIARYGNFVTYDPPVMASTIILWAGPLLFVIIGFTVLVIRSRKNSKLATENSDTLDAEEEARLKAILSDMDQPSDTDKNNNTKVNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ91</accession>
    <name>D0YZ91_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Flagellar secretion chaperone FliS</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_002604</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Cytoplasm</location>
            <location evidence="1 6">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the FliS family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300459.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002604"/>
    <dbReference type="EnsemblBacteria" id="EEZ41572">
        <property type="protein sequence ID" value="EEZ41572"/>
        <property type="gene ID" value="VDA_002604"/>
    </dbReference>
    <dbReference type="GeneID" id="57341149"/>
    <dbReference type="eggNOG" id="COG1516">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1730695at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044780">
        <property type="term" value="P:bacterial-type flagellum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16098">
        <property type="entry name" value="FliS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003713">
        <property type="entry name" value="FliS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036584">
        <property type="entry name" value="FliS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34773">
        <property type="entry name" value="PTHR34773"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02561">
        <property type="entry name" value="FliS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039090">
        <property type="entry name" value="Flis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101116">
        <property type="entry name" value="SSF101116"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00208">
        <property type="entry name" value="fliS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-1005">Bacterial flagellum biogenesis</keyword>
    <keyword evidence="7" id="KW-0966">Cell projection</keyword>
    <keyword evidence="5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="7" id="KW-0969">Cilium</keyword>
    <keyword evidence="3 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0282">Flagellum</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR039090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="131" mass="14654" checksum="F49745362E6AD12F" modified="2010-01-19" version="1">MRGSLQAYKKVSVNAQLASASPHRIIQMLYAGAIERLIQGKAAMEQGNIAMKCERLSKALDIIMSLRDCLSMEDGGDVANNLDSLYDYMIRQVSTANAENQPEPIDEVITMLREIKSAWDQIPSEYHYLTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZA0</accession>
    <name>D0YZA0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Flagellar L-ring protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Basal body L-ring protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">flgH</name>
        <name evidence="12" type="ORF">VDA_002613</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 9">The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell outer membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Bacterial flagellum basal body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the FlgH family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300489.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002613"/>
    <dbReference type="EnsemblBacteria" id="EEZ41581">
        <property type="protein sequence ID" value="EEZ41581"/>
        <property type="gene ID" value="VDA_002613"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2063">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1900876at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009427">
        <property type="term" value="C:bacterial-type flagellum basal body, distal rod, L ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003774">
        <property type="term" value="F:cytoskeletal motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00415">
        <property type="entry name" value="FlgH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000527">
        <property type="entry name" value="Flag_Lring"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34933">
        <property type="entry name" value="PTHR34933"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02107">
        <property type="entry name" value="FlgH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01008">
        <property type="entry name" value="FLGLRINGFLGH"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="9" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="12" id="KW-0966">Cell projection</keyword>
    <keyword evidence="12" id="KW-0969">Cilium</keyword>
    <keyword evidence="12" id="KW-0282">Flagellum</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0564">Palmitate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019896" description="Flagellar L-ring protein" evidence="11">
        <location>
            <begin position="21"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="27"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="27"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ41581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="259" mass="28065" checksum="7BCE9AC03F4EF5CF" modified="2010-01-19" version="1">MKSPIAGLLLLGLLQLVGCASTPDVPQSDIEKGTTTVDAVEGDQSESKGLIDKLRHREDPVAGDPAWGPVRPPVPAEHYVAATGSLFNQTHVQDLYDDTRPHSIGDIVTILLEEKTAAKKSATSELDKSADMNMKPIALGGKPVTIHDYSLSYDFSNDNTFSGSSTADQSNSIKGSISVEVIDILANGNLVIRGEKWLTLNSGDEFIRVSGHIRPDDISQDNTIPSTRISNARIQYSGTGDRQDVQDQNWLSRFFNVAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZD4</accession>
    <name>D0YZD4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Gamma-glutamyl phosphate reductase</fullName>
            <shortName evidence="7">GPR</shortName>
            <ecNumber evidence="7">1.2.1.41</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Glutamate-5-semialdehyde dehydrogenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Glutamyl-gamma-semialdehyde dehydrogenase</fullName>
            <shortName evidence="7">GSA dehydrogenase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">proA</name>
        <name evidence="9" type="ORF">VDA_002647</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>L-glutamate 5-semialdehyde + NADP(+) + phosphate = H(+) + L-glutamyl 5-phosphate + NADPH</text>
            <dbReference type="Rhea" id="RHEA:19541"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58066"/>
            <dbReference type="ChEBI" id="CHEBI:58274"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.2.1.41"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-glutamate: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the gamma-glutamyl phosphate reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.41" evidence="7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002647"/>
    <dbReference type="EnsemblBacteria" id="EEZ41615">
        <property type="protein sequence ID" value="EEZ41615"/>
        <property type="gene ID" value="VDA_002647"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0014">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00098">
        <property type="reaction ID" value="UER00360"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004350">
        <property type="term" value="F:glutamate-5-semialdehyde dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd07079">
        <property type="entry name" value="ALDH_F18-19_ProA-GPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00412">
        <property type="entry name" value="ProA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020593">
        <property type="entry name" value="G-glutamylP_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012134">
        <property type="entry name" value="Glu-5-SA_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000965">
        <property type="entry name" value="GPR_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000151">
        <property type="entry name" value="GPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00407">
        <property type="entry name" value="proA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01223">
        <property type="entry name" value="PROA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7" id="KW-0521">NADP</keyword>
    <keyword evidence="6 7 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 7" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="8">
        <location>
            <begin position="3"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="413" mass="44538" checksum="0007F65D46DB1480" modified="2010-01-19" version="1">MGQAAQKAAFELATVATAQKNQALAIIADELEVQEATILAANEKDIAAARESGMSDALIDRLLLTKDRLVGIANDVRNVIKLNDPVGSEIDCRVLENGMRLSRRRVPLGVIGVIYEARPNVTIDIAALCLKTGNASILRGGRETFHSNMELVKVIQSALDKAGLPAASVQYIEQPDREYVSQLLRLDQYVDMIIPRGGAGLHKMCKENSTIPVIIGGFGISHMFVDASADLTRSLDVVENAKVQRPSACNALDTLLVHEKIAEAFLPRLVERMNAGKVTLVADEAAFALLEGKASSLRLAQDGDFDTEWLSYTLGIKVVADVNEAILHMREHNASHSDSILTNDLMAAERFVNAAGSAAVYVNASTRFTDGAQFGLGAEVAVSTQKLHARGPMGLEELTSYKWVGVADYLSRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZQ5</accession>
    <name>D0YZQ5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Capsular polysaccharide synthesis enzyme CpsC polysaccharide export</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_002768</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002768"/>
    <dbReference type="EnsemblBacteria" id="EEZ41736">
        <property type="protein sequence ID" value="EEZ41736"/>
        <property type="gene ID" value="VDA_002768"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015159">
        <property type="term" value="F:polysaccharide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003715">
        <property type="entry name" value="Poly_export"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019554">
        <property type="entry name" value="Soluble_ligand-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02563">
        <property type="entry name" value="Poly_export"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10531">
        <property type="entry name" value="SLBB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="SLBB" evidence="3">
        <location>
            <begin position="116"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="187" mass="20989" checksum="0DF0D39E89D836E2" modified="2010-01-19" version="1">MKKLIVFIFIFIFIFIFVYVISCISSMSVMAESTAPKNQYLLGAGDHIQILVYNEENLSMNFIVDSSGKVMYPLIGELQLIGKTLDQVSVEIQNRLKNGYIKNPMVTVTMRSFRDFYVSGEVKSPGNFEYHPGLTLEQAIAIAGGFTDRADRDDVSIRLKNGQLLEDVLPTQTVNPGDTVIIDQSFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZQ7</accession>
    <name>D0YZQ7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Chaperone protein DnaJ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">dnaJ</name>
        <name evidence="12" type="ORF">VDA_002770</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8">Binds 2 Zn(2+) ions per monomer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the DnaJ family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300956.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002770"/>
    <dbReference type="EnsemblBacteria" id="EEZ41738">
        <property type="protein sequence ID" value="EEZ41738"/>
        <property type="gene ID" value="VDA_002770"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0484">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1738789at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031072">
        <property type="term" value="F:heat shock protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10719">
        <property type="entry name" value="DnaJ_zf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01152">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012724">
        <property type="entry name" value="DnaJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001305">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036410">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00684">
        <property type="entry name" value="DnaJ_CXXCXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="SSF46565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="SSF49493"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57938">
        <property type="entry name" value="SSF57938"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02349">
        <property type="entry name" value="DnaJ_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51188">
        <property type="entry name" value="ZF_CR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0143">Chaperone</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 8" id="KW-0235">DNA replication</keyword>
    <keyword evidence="2 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 8" id="KW-0346">Stress response</keyword>
    <keyword evidence="5 8 9" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 8 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="J" evidence="10">
        <location>
            <begin position="5"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="CR-type" evidence="11">
        <location>
            <begin position="134"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="repeat" description="CXXCXGXG motif" evidence="8">
        <location>
            <begin position="147"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="repeat" description="CXXCXGXG motif" evidence="8">
        <location>
            <begin position="164"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="repeat" description="CXXCXGXG motif" evidence="8">
        <location>
            <begin position="186"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="repeat" description="CXXCXGXG motif" evidence="8">
        <location>
            <begin position="200"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="CR-type" evidence="9">
        <location>
            <begin position="134"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="200"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ41738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="379" mass="40980" checksum="081F6CC292920D20" modified="2010-01-19" version="1">MSKRDLYEVLGVARDASERDIKKAYKRLAMKFHPDRNQGDEQAAEKFKEVKSAYEILTDSQKRAAYDQYGHAAFEQGGMGGGGFGGGGADFSDIFGDVFGDIFGGGGRRQQQRAQRGADLRYTLELSLEEAVRGCSKEIKVPTLVACDTCHGSGAKEGSTASTCSTCHGVGQVQMRQGFFAVQQTCPHCHGRGKIITDPCGKCHGEGRVEETKTLSVKIPAGVDTGDRIRLAGEGEAGEMGAPAGDLYVQVHVLPHHIFERDGSNLYCEVPVSFTMAALGGEVEVPTLDGRVNLKVPSETQTGRMFRMRGKGVKSVRGGAMGDLICKLVVETPVNLSSRQKELLKELEETFDGKAASKHKPKSEGFFNGVKKFFDDLTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZR6</accession>
    <name>D0YZR6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SsrA-binding protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Small protein B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">smpB</name>
        <name evidence="4" type="ORF">VDA_002779</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="3">The tmRNA-SmpB complex associates with stalled 70S ribosomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SmpB family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300982.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002779"/>
    <dbReference type="EnsemblBacteria" id="EEZ41747">
        <property type="protein sequence ID" value="EEZ41747"/>
        <property type="gene ID" value="VDA_002779"/>
    </dbReference>
    <dbReference type="GeneID" id="57340944"/>
    <dbReference type="eggNOG" id="COG0691">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1720952at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070929">
        <property type="term" value="P:trans-translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09294">
        <property type="entry name" value="SmpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00023">
        <property type="entry name" value="SmpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023620">
        <property type="entry name" value="SmpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000037">
        <property type="entry name" value="SsrA-bd_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020081">
        <property type="entry name" value="SsrA-bd_prot_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30308">
        <property type="entry name" value="PTHR30308"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01668">
        <property type="entry name" value="SmpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74982">
        <property type="entry name" value="SSF74982"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00086">
        <property type="entry name" value="smpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01317">
        <property type="entry name" value="SSRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="160" mass="18048" checksum="92B3C7597FBBBF20" modified="2010-01-19" version="1">MAKKPNKKPGSNTIAKNKSARFEFAITDEYEAGISLQGWEVKAIRDGKVNMTESYVYLRNGEVFISGLTITPLQAASTHVVADPTRIRKLLLNRREIDKLTGAVNRDGETIVALNMYWKASFVKVKIGTARGKKLHDKRADTKARDWQRDKARIMKGSLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZS1</accession>
    <name>D0YZS1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF45 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002784</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300997.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002784"/>
    <dbReference type="EnsemblBacteria" id="EEZ41752">
        <property type="protein sequence ID" value="EEZ41752"/>
        <property type="gene ID" value="VDA_002784"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1451">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1301886at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002725">
        <property type="entry name" value="YgjP-like_metallopeptidase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01863">
        <property type="entry name" value="DUF45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF45" evidence="1">
        <location>
            <begin position="16"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="226" mass="26731" checksum="5D0992F8C8D2B708" modified="2010-01-19" version="1">MQYKDIKYSLKQSKRKTTSILIERDGSVTVLAPESYDIEKVESIVEEKRSWIYRNLAEWEDLNRTKVEREFVSGEGFPYLGRNYRLKLVDEQKEDLILKNGYFLMRRDKTGYGSELFKHFYRTKGLSRISKRVEHFAPKLGVDYRAIRVMDLQHHWASCSPKGDLNFHWRCLMAPLVVLDYIVVHELAHRIEPNHSAAFWNIVDKIMPDYQKHVSWLKHNGAGLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZU7</accession>
    <name>D0YZU7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphopentomutase</fullName>
            <ecNumber evidence="4">5.4.2.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Phosphodeoxyribomutase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">deoB</name>
        <name evidence="6" type="ORF">VDA_002810</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Phosphotransfer between the C1 and C5 carbon atoms of pentose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>2-deoxy-alpha-D-ribose 1-phosphate = 2-deoxy-D-ribose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:27658"/>
            <dbReference type="ChEBI" id="CHEBI:57259"/>
            <dbReference type="ChEBI" id="CHEBI:62877"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>alpha-D-ribose 1-phosphate = D-ribose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:18793"/>
            <dbReference type="ChEBI" id="CHEBI:57720"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="EC" id="5.4.2.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="4">Binds 1 or 2 manganese ions.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Metabolic intermediate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route II): step 1/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the phosphopentomutase family.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.7" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301073.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002810"/>
    <dbReference type="EnsemblBacteria" id="EEZ41778">
        <property type="protein sequence ID" value="EEZ41778"/>
        <property type="gene ID" value="VDA_002810"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1015">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1772797at2"/>
    <dbReference type="UniPathway" id="UPA00087">
        <property type="reaction ID" value="UER00173"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008973">
        <property type="term" value="F:phosphopentomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006015">
        <property type="term" value="P:5-phosphoribose 1-diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043094">
        <property type="term" value="P:cellular metabolic compound salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009264">
        <property type="term" value="P:deoxyribonucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16009">
        <property type="entry name" value="PPM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00740">
        <property type="entry name" value="Phosphopentomut"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010045">
        <property type="entry name" value="DeoB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006124">
        <property type="entry name" value="Metalloenzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024052">
        <property type="entry name" value="Phosphopentomutase_DeoB_cap_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21110">
        <property type="entry name" value="PTHR21110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01676">
        <property type="entry name" value="Metalloenzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001491">
        <property type="entry name" value="Ppentomutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143856">
        <property type="entry name" value="SSF143856"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01696">
        <property type="entry name" value="deoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3 4" id="KW-0464">Manganese</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metalloenzyme" evidence="5">
        <location>
            <begin position="2"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="310"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="346"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="347"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="358"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="406" mass="44101" checksum="07528D1B644679EC" modified="2010-01-19" version="1">MKRSIILVLDSFGIGATEDAATFGDVGANTLGHIAQACARGEADNGERSGPLHLPNLNKLGLGKACEESSGYFPEGLDPNAKIVGAYGHAQEISSGKDTPSGHWEIAGVPVLFEWGYFKEHNNSFPQELLDRIVERANLPGYLGNCHASGTQVLDDLGEEHMATGKPIFYTSADSVFQIACHEETYGLDNLMTLCQIVREELEDYNIGRVIARPFIGAGKGQFERTGNRRDLSIEPPSATVLQKLVDEKQGEVVSIGKISDIYAGCGITKKVKATGIPALFEATLEQIKQAGDNTIVFTNFVDFDSAYGHRRNVAGYAAALEYFDKRLPEILELLQDDDVLLITADHGCDPTWPGTDHTREHIPVLVYGPQIKAGSLGRRATFADIGQSLAQYFGTSDMEFGKSFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZX3</accession>
    <name>D0YZX3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 8">Phosphoglucosamine mutase</fullName>
            <ecNumber evidence="6 8">5.4.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">glmM</name>
        <name evidence="13" type="ORF">VDA_002836</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 8">Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 8">
            <text>alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:23424"/>
            <dbReference type="ChEBI" id="CHEBI:58516"/>
            <dbReference type="ChEBI" id="CHEBI:58725"/>
            <dbReference type="EC" id="5.4.2.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="6">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="PTM">
        <text evidence="6">Activated by phosphorylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.10" evidence="6 8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301152.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002836"/>
    <dbReference type="EnsemblBacteria" id="EEZ41804">
        <property type="protein sequence ID" value="EEZ41804"/>
        <property type="gene ID" value="VDA_002836"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1109">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1265792at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008966">
        <property type="term" value="F:phosphoglucosamine mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05802">
        <property type="entry name" value="GlmM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01554_B">
        <property type="entry name" value="GlmM_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005845">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005846">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005843">
        <property type="entry name" value="A-D-PHexomutase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016066">
        <property type="entry name" value="A-D-PHexomutase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005841">
        <property type="entry name" value="Alpha-D-phosphohexomutase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006352">
        <property type="entry name" value="GlmM_bact"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02879">
        <property type="entry name" value="PGM_PMM_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02880">
        <property type="entry name" value="PGM_PMM_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00408">
        <property type="entry name" value="PGM_PMM_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00509">
        <property type="entry name" value="PGMPMM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="SSF53738"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="SSF55957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01455">
        <property type="entry name" value="glmM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00710">
        <property type="entry name" value="PGM_PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 6 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PGM_PMM_I" evidence="10">
        <location>
            <begin position="4"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_II" evidence="11">
        <location>
            <begin position="157"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_III" evidence="12">
        <location>
            <begin position="258"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_IV" evidence="9">
        <location>
            <begin position="375"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphoserine intermediate" evidence="6">
        <location>
            <position position="102"/>
        </location>
    </feature>
    <feature type="binding site" description="via phosphate group" evidence="6">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="241"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="243"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="245"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="Phosphoserine" evidence="6">
        <location>
            <position position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ41804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="445" mass="47612" checksum="1EBCFBC4893DE166" modified="2010-01-19" version="1">MQERKYFGTDGVRGLVGEGPITPEFVLKLGWAAGRVLSQQGTKKVLIGKDTRISGYMLESALEAGLAAAGLQAAFTGPMPTPAIAYLTRTFRAEAGIVISASHNPYYDNGIKFFSSEGTKLPDEVELAIEAELDKPLTCVESALLGKAYRINDAAGRYIEFCKGTFPSQHNLSGYKIVVDCAHGATYHIAPNVFRELGADVITIGCEPNGTNINDKVGATDIAALQAKVLEEKADFGIALDGDGDRVIMVDEAGNKVDGDQIAYIIARDALRRGELKGGVVGTLMTNMGMEVALKNLGIPFVRAKVGDRYVMEELLKHNWLIGAENSGHVILLDKVTTGDGIVAGLQIMAAMVSSKMTLKELSEGMKMFPQVLENVRFKGDGNPLESEAVIAATKAVEEKLGETGRVLLRKSGTEPLIRVMVEGEDGDAVAQYALDIAQAVKDNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZY5</accession>
    <name>D0YZY5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">4-hydroxy-3-methylbut-2-enyl diphosphate reductase</fullName>
            <shortName evidence="5">HMBPP reductase</shortName>
            <ecNumber evidence="5">1.17.7.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ispH</name>
        <name evidence="6" type="ORF">VDA_002848</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>H2O + isopentenyl diphosphate + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:24488"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:128753"/>
            <dbReference type="ChEBI" id="CHEBI:128769"/>
            <dbReference type="EC" id="1.17.7.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>dimethylallyl diphosphate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:24825"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57623"/>
            <dbReference type="ChEBI" id="CHEBI:128753"/>
            <dbReference type="EC" id="1.17.7.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="5">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Isoprenoid biosynthesis; dimethylallyl diphosphate biosynthesis; dimethylallyl diphosphate from (2E)-4-hydroxy-3-methylbutenyl diphosphate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 6/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the IspH family.</text>
    </comment>
    <dbReference type="EC" id="1.17.7.4" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301187.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002848"/>
    <dbReference type="EnsemblBacteria" id="EEZ41816">
        <property type="protein sequence ID" value="EEZ41816"/>
        <property type="gene ID" value="VDA_002848"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0761">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1311145at2"/>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00097"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00059">
        <property type="reaction ID" value="UER00105"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051745">
        <property type="term" value="F:4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050992">
        <property type="term" value="P:dimethylallyl diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd13944">
        <property type="entry name" value="lytB_ispH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00191">
        <property type="entry name" value="IspH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003451">
        <property type="entry name" value="LytB/IspH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30426">
        <property type="entry name" value="PTHR30426"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02401">
        <property type="entry name" value="LYTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00216">
        <property type="entry name" value="ispH_lytB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3 5" id="KW-0408">Iron</keyword>
    <keyword evidence="4 5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="227"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="126"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="12"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="271"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="315" mass="34878" checksum="192E1F6DBA28526F" modified="2010-01-19" version="1">MKILLANPRGFCAGVDRAISIVERALEMYQPPIYVRHEVVHNRFVVEGLKQRGAIFVEELSEVPDDNIVIFSAHGVSQAVRNEAKARQLTVFDATCPLVTKVHMEVARASRKHMEVVLIGHAGHPEVEGTMGQYSSDEGGMYLVENPDDVQALRDKVKDPSNLHFVSQTTLSVDETSDVINTLRQVFPAIQGPRKDDICYATQNRQDAVREMAKNVDVMIVVGSKNSSNSNRLRELAEKLGTPGYLTDCADDIDPNWLSDVQTVGVTAGASAPEELVNQIIARIKALGDAEVEELTGREENMFFEVPRELQVKNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z026</accession>
    <name>D0Z026_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glutamate synthase [NADPH] small chain</fullName>
            <ecNumber evidence="7">1.4.1.13</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_002889</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="5">Amino-acid biosynthesis.</text>
    </comment>
    <dbReference type="EC" id="1.4.1.13" evidence="7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301278.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002889"/>
    <dbReference type="EnsemblBacteria" id="EEZ41857">
        <property type="protein sequence ID" value="EEZ41857"/>
        <property type="gene ID" value="VDA_002889"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0493">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="671513at2"/>
    <dbReference type="UniPathway" id="UPA00282"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004355">
        <property type="term" value="F:glutamate synthase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006537">
        <property type="term" value="P:glutamate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028261">
        <property type="entry name" value="DPD_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006005">
        <property type="entry name" value="Glut_synth_ssu1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14691">
        <property type="entry name" value="Fer4_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01317">
        <property type="entry name" value="GOGAT_sm_gam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0314">Glutamate biosynthesis</keyword>
    <keyword evidence="3 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="6">
        <location>
            <begin position="38"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00029440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="488" mass="53184" checksum="40021840146E6042" modified="2010-01-19" version="1">MGKPTGFLEFGRELPKKVDPSVRIQDNKEFVLDNEFGDKINQQASRCMDCGVPFCHNACPIGNIIPEFNDAVYRDSWEEAWHILSSTNNFPEFTGRVCPAPCESGCVLGINQDPITICNIEKNIVERAYKEGYAKPKTPRARTGKTVAIIGSGPAGLAAAEQLNSAGHTVTVFERDEKVGGLLRFGIPDFKLGMNIIDRKIDLMAKAGIEFVVNAHIGVDINALQLRQDFDVVLLTGGSTVPRNLPIPGRELTGVHFAMEFLAQNNRRANNMDLKATEIHAKDKHVVVIGGGDTGSDCVGTSNRHGASSITQLEILPVPPETRPSNQPWPSYPMIMKTSTSHEEGCDRFWNILTKAFIGDDNGNVKALRIADITWDEAKEGERPSFTEVPGSERIIPCDLAFLAMGFLHPEPTGVLAQLDIALDDRGNVATTGYATNQAGIFAAGDMRTGQSLVVRCINEGRECARAIDNYLMGNSQLEAKADSLMLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z060</accession>
    <name>D0Z060_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Beta-mannosidase</fullName>
            <ecNumber evidence="6">3.2.1.25</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_002923</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 2 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.25" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301364.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002923"/>
    <dbReference type="EnsemblBacteria" id="EEZ41891">
        <property type="protein sequence ID" value="EEZ41891"/>
        <property type="gene ID" value="VDA_002923"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3250">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="245411at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004567">
        <property type="term" value="F:beta-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036156">
        <property type="entry name" value="Beta-gal/glucu_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041625">
        <property type="entry name" value="Beta-mannosidase_Ig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006102">
        <property type="entry name" value="Glyco_hydro_2_Ig-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00703">
        <property type="entry name" value="Glyco_hydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17753">
        <property type="entry name" value="Ig_mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49303">
        <property type="entry name" value="SSF49303"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro_2" evidence="4">
        <location>
            <begin position="229"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="Ig_mannosidase" evidence="5">
        <location>
            <begin position="730"/>
            <end position="806"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="808" mass="93473" checksum="C14A9280B6D8F0A3" modified="2010-01-19" version="1">MTISLNGQWILTCVQRAAIQDITVELPGDVHSALLEAGEIPDPHWATNEDKVQWIRECDWLVSRSFQLTEDQLTCQAMDLVLHDLESIVEIRVNGHTVADFNNMFIRHKVEILPCLKVGLNHIEMVLRHQDPTQVALDKLAFNMPIDEQGTAQIDLNALRQSSCLSSSFWGVNIPVIGVFDDIELQPLQQIRVSHISTKQNWQESGCELAVTLHYEAVTSRGLAIAEVTFDDQTFHLTLDRDAEQASVLFRIDNPRLWWPAGYGQPRLYDLRVEVDGQLIEQKIGLRKLEVVTEPNEQGHNFSVKVNDELIKVRGTNWLPLDALPGRMTAERYQKLLADAAEANMNMVRVWGGGRYEKEIFYRQCDALGLLVWQDVMFSDAFMLPTPDVMTEVKEELLWQARRLKNHSCIALWGGDNPIVDGIYQQLPNRQERDKYLSNYDRLMRNIRQVLEQEDPKRLFWVSASYYDDSEHCRPWQDLDSGDCHYWDIWHQGLDYVHSRKHIPNFCSEFGFQSWPSLPTVRTIAPEKHWNISSPSMEQHQRNGKGNATIVDMFTRNYRFPDGFANMLYLSQVQQAIVTKTAVEAWRLQEKNTGMLLWQLNDFSPQSSCSSVEYNGRWKPLHYHAKRFFAPLTATFMADNDGVKLYLLNDSRRGEVLKGEVVWQSWEGEILFRDPINQYLEPGKCLSVWEWLTEDLAGREEEGFFHVHLRQGANIIENTWFPKRLKHCELADPDLRYEVAEIDNQLYVMITSSKPAFFVHLEYQGAGHFSDSSFTLVPEHQRQIKYTGPATLEELTAGLTVYHLRNSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0B2</accession>
    <name>D0Z0B2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Chaperone SurA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Peptidyl-prolyl cis-trans isomerase SurA</fullName>
            <shortName evidence="5">PPIase SurA</shortName>
            <ecNumber evidence="5">5.2.1.8</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Rotamase SurA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">surA</name>
        <name evidence="8" type="ORF">VDA_002975</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Periplasm</location>
        </subcellularLocation>
        <text evidence="5">Is capable of associating with the outer membrane.</text>
    </comment>
    <comment type="domain">
        <text evidence="5">The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002975"/>
    <dbReference type="EnsemblBacteria" id="EEZ41943">
        <property type="protein sequence ID" value="EEZ41943"/>
        <property type="gene ID" value="VDA_002975"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0760">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042277">
        <property type="term" value="F:peptide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043165">
        <property type="term" value="P:Gram-negative-bacterium-type cell outer membrane assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050821">
        <property type="term" value="P:protein stabilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01183">
        <property type="entry name" value="Chaperone_SurA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000297">
        <property type="entry name" value="PPIase_PpiC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023058">
        <property type="entry name" value="PPIase_PpiC_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023034">
        <property type="entry name" value="PPIase_SurA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015391">
        <property type="entry name" value="SurA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027304">
        <property type="entry name" value="Trigger_fact/SurA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00639">
        <property type="entry name" value="Rotamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09312">
        <property type="entry name" value="SurA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109998">
        <property type="entry name" value="SSF109998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01096">
        <property type="entry name" value="PPIC_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50198">
        <property type="entry name" value="PPIC_PPIASE_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4 5 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2 5" id="KW-0574">Periplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5 6" id="KW-0697">Rotamase</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="domain" description="PpiC" evidence="7">
        <location>
            <begin position="96"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="PpiC" evidence="7">
        <location>
            <begin position="206"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ41943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="357" mass="40011" checksum="2D2A83BDC40E9AC6" modified="2010-01-19" version="1">METLQVQQAKQMGIRIDDSQLEQAIGQIAKERNMSIDQLRQQLAQYGISFADFRDQIRRDLMASEARTAIVRRRINILPQEVENLAQQLGQQTQQNTEYNISQIQIRVDESASKAERDAAKEEADKLVKDLNDGADFAKLAYTYSKGPKALKGGEWGWMSKEEMPTIFADQIKNNGKGAIIGPFRSGVGYHILKINDVKGLQTVSVMEVKARHILLKPSVILSDAGAKQELEQVRQKILSGKETFAQAAKAISQDPGSAANGGELGWQTPDLYVPAFKDKVETLPVDTISQPFKTVHGWHIVEVEGRRNVDRTDAALKNRAYRILFNRKFNEEAQTWLQELRASAYIDNLTNTGNNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0E0</accession>
    <name>D0Z0E0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Siroheme synthase</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="14">Uroporphyrinogen-III C-methyltransferase</fullName>
                <shortName evidence="14">Urogen III methylase</shortName>
                <ecNumber evidence="14">2.1.1.107</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="14">SUMT</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="14">Uroporphyrinogen III methylase</fullName>
                <shortName evidence="14">UROM</shortName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="14">Precorrin-2 dehydrogenase</fullName>
                <ecNumber evidence="14">1.3.1.76</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="14">Sirohydrochlorin ferrochelatase</fullName>
                <ecNumber evidence="14">4.99.1.4</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="14" type="primary">cysG</name>
        <name evidence="20" type="ORF">VDA_003004</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>2 H(+) + siroheme = Fe(2+) + sirohydrochlorin</text>
            <dbReference type="Rhea" id="RHEA:24360"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:58351"/>
            <dbReference type="ChEBI" id="CHEBI:60052"/>
            <dbReference type="EC" id="4.99.1.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>2 S-adenosyl-L-methionine + uroporphyrinogen III = H(+) + precorrin-2 + 2 S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:32459"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57308"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:58827"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="EC" id="2.1.1.107"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>NAD(+) + precorrin-2 = 2 H(+) + NADH + sirohydrochlorin</text>
            <dbReference type="Rhea" id="RHEA:15613"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58351"/>
            <dbReference type="ChEBI" id="CHEBI:58827"/>
            <dbReference type="EC" id="1.3.1.76"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="14">Cofactor biosynthesis; adenosylcobalamin biosynthesis; precorrin-2 from uroporphyrinogen III: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="14">Cofactor biosynthesis; adenosylcobalamin biosynthesis; sirohydrochlorin from precorrin-2: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="13 14">Porphyrin-containing compound metabolism; siroheme biosynthesis; precorrin-2 from uroporphyrinogen III: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="14">Porphyrin-containing compound metabolism; siroheme biosynthesis; siroheme from sirohydrochlorin: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 14">Porphyrin-containing compound metabolism; siroheme biosynthesis; sirohydrochlorin from precorrin-2: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 16">Belongs to the precorrin methyltransferase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="14">In the C-terminal section; belongs to the precorrin methyltransferase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="14">In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.107" evidence="14"/>
    <dbReference type="EC" id="1.3.1.76" evidence="14"/>
    <dbReference type="EC" id="4.99.1.4" evidence="14"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301543.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003004"/>
    <dbReference type="EnsemblBacteria" id="EEZ41971">
        <property type="protein sequence ID" value="EEZ41971"/>
        <property type="gene ID" value="VDA_003004"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0007">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1648">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1185397at2"/>
    <dbReference type="UniPathway" id="UPA00148">
        <property type="reaction ID" value="UER00211"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00262">
        <property type="reaction ID" value="UER00211"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043115">
        <property type="term" value="F:precorrin-2 dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051266">
        <property type="term" value="F:sirohydrochlorin ferrochelatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004851">
        <property type="term" value="F:uroporphyrin-III C-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019354">
        <property type="term" value="P:siroheme biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd11642">
        <property type="entry name" value="SUMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01646">
        <property type="entry name" value="Siroheme_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006366">
        <property type="entry name" value="CobA/CysG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037115">
        <property type="entry name" value="Sirohaem_synt_dimer_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012409">
        <property type="entry name" value="Sirohaem_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028281">
        <property type="entry name" value="Sirohaem_synthase_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019478">
        <property type="entry name" value="Sirohaem_synthase_dimer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006367">
        <property type="entry name" value="Sirohaem_synthase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003043">
        <property type="entry name" value="Uropor_MeTrfase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10414">
        <property type="entry name" value="CysG_dimeriser"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14824">
        <property type="entry name" value="Sirohm_synth_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036426">
        <property type="entry name" value="Sirohaem_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="SSF53790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01469">
        <property type="entry name" value="cobA_cysG_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01470">
        <property type="entry name" value="cysG_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00839">
        <property type="entry name" value="SUMT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00840">
        <property type="entry name" value="SUMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 14" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="10 14 20" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 14 16" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12 14" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="9 14" id="KW-0520">NAD</keyword>
    <keyword evidence="8 14 20" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11 14" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 14" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6 14 16" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Sirohm_synth_M" evidence="19">
        <location>
            <begin position="124"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="CysG_dimeriser" evidence="18">
        <location>
            <begin position="150"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="TP_methylase" evidence="17">
        <location>
            <begin position="216"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase" evidence="14">
        <location>
            <begin position="1"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Uroporphyrinogen-III C-methyltransferase" evidence="14">
        <location>
            <begin position="214"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="14">
        <location>
            <begin position="299"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="14">
        <location>
            <begin position="329"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="14 15">
        <location>
            <position position="246"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="14 15">
        <location>
            <position position="268"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="22"/>
            <end position="23"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="43"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="223"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="304"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="381"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="410"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="Phosphoserine" evidence="14">
        <location>
            <position position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00025705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR036426-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU003960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF10414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF14824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="EEZ41971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="469" mass="51030" checksum="1C00C56AF7AC7512" modified="2010-01-19" version="1">MEYLPIFADINRRPCLVVGGGEVAWRKTQMLLQAGANVHLVAKSVSPEIQAAITNQQVVLLADSFSPELLNGMFLAIAATDSKAVNTLVYQAANQRQILVNVVDDTQRCSFIVPSIIDRSPIVIAISSAGKAPVLARLVREKLETLLPQHLGKMAQVAGEFRAQLKQVLPSFSARRHFWEQAFRGRFAQLIASNNIEQAKAELITLSYQSNPVGHVSLVGAGPGDPDLLTLKALQQMQQADVVLYDQLVSPQILELVRREAQLVSVGKKAGCHSVPQEQTNQLLVAFALQGKKVVRLKGGDPFIFGRGGEELEVLVEHGIEFDVVPGITAAAGATSYAGIPLTHRDYAQSAMFITGHLKQEQDDLDWSTLARGRQTLVIYMGLLKSSYIQQQLLAYGRSSHTPIAIIERGTQAEQKVLVGQLSQLSELAKQAQSPSLIVIGEVVALQSKLQWFNQTQSQPSSAAVVNLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0E1</accession>
    <name>D0Z0E1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">2',3'-cyclic-nucleotide 2'-phosphodiesterase</fullName>
            <ecNumber evidence="10">3.1.4.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_003005</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a nucleoside 2',3'-cyclic phosphate + H2O = a nucleoside 3'-phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19621"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:66949"/>
            <dbReference type="ChEBI" id="CHEBI:66954"/>
            <dbReference type="EC" id="3.1.4.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a ribonucleoside 3'-phosphate + H2O = a ribonucleoside + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10144"/>
            <dbReference type="ChEBI" id="CHEBI:13197"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:18254"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="EC" id="3.1.3.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4 7">Belongs to the 5'-nucleotidase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.16" evidence="10"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301546.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003005"/>
    <dbReference type="EnsemblBacteria" id="EEZ41972">
        <property type="protein sequence ID" value="EEZ41972"/>
        <property type="gene ID" value="VDA_003005"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0737">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1884225at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110165">
        <property type="term" value="C:cellular anatomical entity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008663">
        <property type="term" value="F:2',3'-cyclic-nucleotide 2'-phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008254">
        <property type="term" value="F:3'-nucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009166">
        <property type="term" value="P:nucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07410">
        <property type="entry name" value="MPP_CpdB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008334">
        <property type="entry name" value="5'-Nucleotdase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036907">
        <property type="entry name" value="5'-Nucleotdase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006146">
        <property type="entry name" value="5'-Nucleotdase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006179">
        <property type="entry name" value="5_nucleotidase/apyrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041827">
        <property type="entry name" value="CpdB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006294">
        <property type="entry name" value="Cyc_nuc_PDE_nucleotidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575">
        <property type="entry name" value="PTHR11575"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02872">
        <property type="entry name" value="5_nucleotid_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01607">
        <property type="entry name" value="APYRASEFAMLY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55816">
        <property type="entry name" value="SSF55816"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01390">
        <property type="entry name" value="CycNucDiestase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00786">
        <property type="entry name" value="5_NUCLEOTIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005126060" evidence="7">
        <location>
            <begin position="26"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="domain" description="Metallophos" evidence="8">
        <location>
            <begin position="30"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="5_nucleotid_C" evidence="9">
        <location>
            <begin position="363"/>
            <end position="556"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ41972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="655" mass="72238" checksum="313C3EC1106AAD29" modified="2010-01-19" version="1">MKLSAKPLSIAVLGGLLAIAGPATAETIKLRILETTDIHTNVMDYDYYKDKPTEKTGLVRTATLVEKARDEVPNAILVDNGDLLQGSPMGDYMAAKGIKKGEVHPVYKVMNQLDYEVGNIGNHEFNYGLDFLKTSLEGATFPYVNANVYDLKTGKNLFTPYLIKTHTFTDTDGKAHQIKVGYIGFVPPQIMVWDKKNLEGKVEAKDIKQTAEKFIPQMKAEGADIIIAIPHSGVSADPYKVMAENSVYYLTQVKGIDAIAFGHSHAVFPGKDFAKLPGADIKKGTINGIPAVMPGRWGDHVGVMDLVLDKQGDSWKVIDAQTEARPIFDMAKNKPIVDADPKLVAAVKVDHNATRDFVNQPLGKASDEMYSFLALVQDDPTVQIVNLAQKDYVERFIQGDPDLADIPVLSAAAPFKAGGRGNDPTNFTEVEQGELTFRNAADLYLYPNTLVALKVSGQDVKEWLECSAGQFNQIDPNKTEPQGLINWEGFRTYNFDVIDGVTYNIDLTQPARYDGECKLINPDSHRIKDLEFNGKAVDPKQAFIIATNNYRAYSGKFAGTGEKHIAFAAPDENRTVLAEYISRVSKEKGQVVPSADNNWHFRPIKSEKPVTITFETSPTEKAAEFIKEKGQYPMKQVGTDKVGFAVYNLDLSAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0G9</accession>
    <name>D0Z0G9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GTPase HflX</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">GTP-binding protein HflX</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">hflX</name>
        <name evidence="9" type="ORF">VDA_003033</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer. Associates with the 50S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="5">May associate with membranes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301649.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003033"/>
    <dbReference type="EnsemblBacteria" id="EEZ42000">
        <property type="protein sequence ID" value="EEZ42000"/>
        <property type="gene ID" value="VDA_003033"/>
    </dbReference>
    <dbReference type="GeneID" id="57340511"/>
    <dbReference type="eggNOG" id="COG2262">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1592033at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01878">
        <property type="entry name" value="HflX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00900">
        <property type="entry name" value="GTPase_HflX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030394">
        <property type="entry name" value="G_HFLX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032305">
        <property type="entry name" value="GTP-bd_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016496">
        <property type="entry name" value="GTPase_HflX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025121">
        <property type="entry name" value="GTPase_HflX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042108">
        <property type="entry name" value="GTPase_HflX_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045498">
        <property type="entry name" value="HflX_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10229">
        <property type="entry name" value="PTHR10229"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16360">
        <property type="entry name" value="GTP-bdg_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13167">
        <property type="entry name" value="GTP-bdg_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19275">
        <property type="entry name" value="HflX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006809">
        <property type="entry name" value="GTP-binding_hflX_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03156">
        <property type="entry name" value="GTP_HflX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51705">
        <property type="entry name" value="G_HFLX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hflx-type G" evidence="8">
        <location>
            <begin position="198"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="204"/>
            <end position="211"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="229"/>
            <end position="233"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="251"/>
            <end position="254"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="317"/>
            <end position="320"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR006809-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR006809-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ42000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="429" mass="48502" checksum="E75BE3EE11753306" modified="2010-01-19" version="1">MFDRYEAGEQAVLVHVNFTQEGEWEDLREFEMLVSSAGVNSLRVVTGSRKTPHPKYYVGEGKALEIADAVRAVDADIVIFNHALSPAQERNLEQLCQCRVVDRTGLILDIFAQRARTHEGKLQVELAQLRHLSTRLIRGWTHLERQKGGIGLRGPGETQLETDRRLLRERIKAILRRLDKVAKQREQGRRARNRAEIPTISLVGYTNAGKSTLFNRITDAGVYAADQLFATLDPTLRKVEVADVGTAILADTVGFIRHLPHDLVAAFKATLKETQEADLLLHVVDASDDRFRENIDAVESVLEEIEAHEVPSLLVMNKIDNLEGAKPRIERDDDGVPRRVWVSAMEGIGLDLLFQALTERLSGTMVKHTLRLPPELIGRYRSKFYQLGCILREEYESDGCLTIDIRIQLADWSRLQKRESTSLDDFIVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0I2</accession>
    <name>D0Z0I2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Elongation factor P--(R)-beta-lysine ligase</fullName>
            <shortName evidence="2">EF-P--(R)-beta-lysine ligase</shortName>
            <ecNumber evidence="2">6.3.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">EF-P post-translational modification enzyme A</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">EF-P-lysine lysyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">epmA</name>
        <name evidence="4" type="ORF">VDA_003046</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.3.1.-" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301683.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003046"/>
    <dbReference type="EnsemblBacteria" id="EEZ42013">
        <property type="protein sequence ID" value="EEZ42013"/>
        <property type="gene ID" value="VDA_003046"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2269">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="63621at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016880">
        <property type="term" value="F:acid-ammonia (or amide) ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004824">
        <property type="term" value="F:lysine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006430">
        <property type="term" value="P:lysyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071915">
        <property type="term" value="P:protein-lysine lysylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00174">
        <property type="entry name" value="EF_P_modif_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004525">
        <property type="entry name" value="EpmA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00462">
        <property type="entry name" value="genX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="1 2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="3">
        <location>
            <begin position="14"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="74"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="98"/>
            <end position="100"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="242"/>
            <end position="243"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="249"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="298"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ42013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="323" mass="36312" checksum="EE5FE82AD38942B8" modified="2010-01-19" version="1">MQMTWQPTADVAMLKQRAKLIAAIRQFFYQRDVLEVDTPAMSQATVTDIHLHTFKTEFVGPGFADGQILYLMTSPEFHMKRLLSAGSGAIYQICKSFRNEESGRYHNPEFTMLEWYRPGFDHHQLMDEMDELLQLILGCQQAERMSYQQAFLNVLGVCPLEGSMLELKQAAAKLGLSDIAEPEEDRDTLLQLLFSIGIEGKIGQKVPAFVYDFPASQAALAQINPTDNRVAERFEVYFKGIELANGFHELANGDEQLIRFEADNHKRIEMGLEPQPIDMNLVNALRAGFPDCAGVALGIDRLIMLALGLKHIDQVTAFPVDIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0I6</accession>
    <name>D0Z0I6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Fumarate reductase subunit D</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Quinol-fumarate reductase subunit D</fullName>
            <shortName evidence="1">QFR subunit D</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">frdD</name>
        <name evidence="2" type="ORF">VDA_003050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Anchors the catalytic components of the fumarate reductase complex to the cell membrane, binds quinones.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the FrdD family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301695.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003050"/>
    <dbReference type="EnsemblBacteria" id="EEZ42017">
        <property type="protein sequence ID" value="EEZ42017"/>
        <property type="gene ID" value="VDA_003050"/>
    </dbReference>
    <dbReference type="GeneID" id="57340475"/>
    <dbReference type="eggNOG" id="COG3080">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2071715at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045284">
        <property type="term" value="C:plasma membrane fumarate reductase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000104">
        <property type="term" value="F:succinate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006106">
        <property type="term" value="P:fumarate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00547">
        <property type="entry name" value="QFR_TypeD_subunitD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00709">
        <property type="entry name" value="Fumarate_red_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003418">
        <property type="entry name" value="Fumarate_red_D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034804">
        <property type="entry name" value="SQR/QFR_C/D"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02313">
        <property type="entry name" value="Fumarate_red_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000179">
        <property type="entry name" value="FrdD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81343">
        <property type="entry name" value="SSF81343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="120" mass="13309" checksum="8D78194B57806A56" modified="2010-01-19" version="1">MVNLHPKRSDEPVWWSLFGAGGTWFAMITPVTVLVLGIMVPLGMIDPEAMSYERVSSFATSFIGALFIIATLSLPMWHAMHRLHHGMHDLKFHTGTVGKVACYATAFLVTALSIIFVFMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0J5</accession>
    <name>D0Z0J5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Chaperonin GroEL</fullName>
            <ecNumber evidence="6">5.6.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">60 kDa chaperonin</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Chaperonin-60</fullName>
            <shortName evidence="6">Cpn60</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">groEL</name>
        <name evidence="6" type="synonym">groL</name>
        <name evidence="9" type="ORF">VDA_003059</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 8">Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6 8">Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the chaperonin (HSP60) family.</text>
    </comment>
    <dbReference type="EC" id="5.6.1.7" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301718.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="SMR" id="D0Z0J5"/>
    <dbReference type="STRING" id="675817.VDA_003059"/>
    <dbReference type="EnsemblBacteria" id="EEZ42026">
        <property type="protein sequence ID" value="EEZ42026"/>
        <property type="gene ID" value="VDA_003059"/>
    </dbReference>
    <dbReference type="GeneID" id="57340471"/>
    <dbReference type="eggNOG" id="COG0459">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="265347at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03344">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00600">
        <property type="entry name" value="CH60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018370">
        <property type="entry name" value="Chaperonin_Cpn60_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001844">
        <property type="entry name" value="Cpn60/GroEL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00298">
        <property type="entry name" value="CHAPERONIN60"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="SSF48592"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="SSF52029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02348">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00296">
        <property type="entry name" value="CHAPERONINS_CPN60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0346">Stress response</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="30"/>
            <end position="33"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="87"/>
            <end position="91"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="415"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="479"/>
            <end position="481"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="495"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ42026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="547" mass="57412" checksum="7EA095C657C7ADDB" modified="2010-01-19" version="1">MAAKDVKFGNDARIKMLEGVNVLADAVKVTLGPKGRNVVLDKSFGAPTITKDGVSVAREIELEDKFQNMGAQMVKEVASQANDAAGDGTTTATVLAQAIITEGLKAVAAGMNPMDLKRGIDKAVVAAVEELKALSVPCADTKAIAQVGTISANSDATVGNLIAEAMDKVGRDGVITVEEGQALQDELDVVEGMQFDRGYLSPYFINNQEAGAVELESPFILLVDKKISNIRELLPALEGVAKASRPLLIIAEDVEGEALATLVVNNMRGIVKVAAVKAPGFGDRRKAMLQDIAVLTAGTVISEEVGLELEKVQLEDLGQAKRVTITKENTTIIDGFGEEEMIAGRVAQIRQQIEDATSDYDKEKLQERVAKLAGGVAVIKVGAATEVEMKEKKDRVEDALHATRAAVEEGVVAGGGVALIRAASKLTELTGDNEEQNVGIRVALRAMEAPIRQITKNAGDEESVVANNVKGGEGNYGYNAATGEYGDMIDMGILDPTKVTRSALQFAASVAGLMITTEAMVTDLPQKDAGVPDMGGMGGMGGMGGMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0L1</accession>
    <name>D0Z0L1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">tRNA-dihydrouridine synthase B</fullName>
            <ecNumber evidence="10">1.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">dusB</name>
        <name evidence="14" type="ORF">VDA_003075</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 10 11">Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 10">
            <text>a 5,6-dihydrouridine in tRNA + NAD(+) = a uridine in tRNA + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:54452"/>
            <dbReference type="Rhea" id="RHEA-COMP:13339"/>
            <dbReference type="Rhea" id="RHEA-COMP:13887"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>a 5,6-dihydrouridine in tRNA + NADP(+) = a uridine in tRNA + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:23624"/>
            <dbReference type="Rhea" id="RHEA-COMP:13339"/>
            <dbReference type="Rhea" id="RHEA-COMP:13887"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 10 11">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the Dus family. DusB subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the dus family.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.-" evidence="10"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003075"/>
    <dbReference type="EnsemblBacteria" id="EEZ42042">
        <property type="protein sequence ID" value="EEZ42042"/>
        <property type="gene ID" value="VDA_003075"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0042">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017150">
        <property type="term" value="F:tRNA dihydrouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02801">
        <property type="entry name" value="DUS_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02042">
        <property type="entry name" value="DusB_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035587">
        <property type="entry name" value="DUS-like_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001269">
        <property type="entry name" value="DUS_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032887">
        <property type="entry name" value="DusB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024036">
        <property type="entry name" value="tRNA-dHydroUridine_Synthase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004652">
        <property type="entry name" value="tRNA_dU_NifR3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018517">
        <property type="entry name" value="tRNA_hU_synthase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01207">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006621">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00737">
        <property type="entry name" value="nifR3_yhdG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01136">
        <property type="entry name" value="UPF0034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 10 11" id="KW-0288">FMN</keyword>
    <keyword evidence="10" id="KW-0521">NADP</keyword>
    <keyword evidence="9 10 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7 10 11" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="10" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Dus" evidence="13">
        <location>
            <begin position="40"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10 12">
        <location>
            <position position="127"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="43"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="227"/>
            <end position="229"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="251"/>
            <end position="252"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00002790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR006621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR006621-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEZ42042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="348" mass="38778" checksum="43C1B015182F7A03" modified="2010-01-19" version="1">MLNYWPFQNGKKCVKCAPLLTQLGTNILQIGPYQLKNQLIVAPMAGVTDRPFRELCLRYGAGMAVSEMMSSNPDLWKTSKSMNRMVHEGESGIRSVQIAGSDPKLMAEAAQFSVENGAQIIDINMGCPAKKVNKRLAGSALLQYPHLIEEILKEVVGAVDVPVTLKTRTGWDTENRNCVDIAKLAEQCGIQALALHGRTKACMYKGEAEYDYIRAVKQAVTIPVIANGDIDSPEKARFVLDYTGADALMIGRPAQGKPWIFREIHHYLTTGEHLAPPSFDEVSEIMLGHVRELHRFYGEYLGLRIARKHVSWYLKEHAPAGNFRQTFNAIEDANEQIDALQGYFENVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0Y5</accession>
    <name>D0Z0Y5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">N5-carboxyaminoimidazole ribonucleotide synthase</fullName>
            <shortName evidence="3 5">N5-CAIR synthase</shortName>
            <ecNumber evidence="3 5">6.3.4.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3 5">5-(carboxyamino)imidazole ribonucleotide synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 5" type="primary">purK</name>
        <name evidence="8" type="ORF">VDA_003199</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).</text>
    </comment>
    <comment type="function">
        <text evidence="5">Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 5">
            <text>5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + ATP + hydrogencarbonate = 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + ADP + 2 H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:19317"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58730"/>
            <dbReference type="ChEBI" id="CHEBI:137981"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.18"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 5">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5-phospho-D-ribosyl)imidazole (N5-CAIR route): step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the PurK/PurT family.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.18" evidence="3 5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302140.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003199"/>
    <dbReference type="EnsemblBacteria" id="EEZ42166">
        <property type="protein sequence ID" value="EEZ42166"/>
        <property type="gene ID" value="VDA_003199"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0026">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1165275at2"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00942"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034028">
        <property type="term" value="F:5-(carboxyamino)imidazole ribonucleotide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004638">
        <property type="term" value="F:phosphoribosylaminoimidazole carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01928">
        <property type="entry name" value="PurK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003135">
        <property type="entry name" value="ATP-grasp_carboxylate-amine"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005875">
        <property type="entry name" value="PurK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040686">
        <property type="entry name" value="PurK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02222">
        <property type="entry name" value="ATP-grasp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17769">
        <property type="entry name" value="PurK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="SSF51246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01161">
        <property type="entry name" value="purK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5" id="KW-0436">Ligase</keyword>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="3 4 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1 3 5" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019293" description="N5-carboxyaminoimidazole ribonucleotide synthase" evidence="6">
        <location>
            <begin position="19"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="7">
        <location>
            <begin position="97"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="138"/>
            <end position="144"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="175"/>
            <end position="178"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="258"/>
            <end position="259"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ42166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="373" mass="40637" checksum="C6A9CAD1BB06196D" modified="2010-01-19" version="1">MQVLILGAGQLARMMSLAATPLNINVLAFDVTTNTIVHPISGQTYPYSLEQAIAQSDVITAEFEHIAHDILDLCQQSGKLFPAPETIKIGGDRAKEKALLDNAQVASAPYHIIHNQDDLISAITAIGLPLVLKSTLGGYDGKGQWRLHDQHDVASLWPQLAACIAATPNQAIIAEAWIPFQREVSIIGVRDKQGNITTYPLTENIHTNGVLSLSTALIEDNQLQQQANCIFSQVAEQLDYVGVLAIELFDVNDQLLVNEIAPRVHNSGHWTQQGTLCCQFANHIRAVCGLPCGDSAARCASAMINILGIDSLPTEIYQLPYCSVHWYGKEARVGRKMGHINVTAATTEQLQLALQHLGSILPETQFPALPREH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1D0</accession>
    <name>D0Z1D0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DNA repair protein RadC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_003344</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the UPF0758 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302532.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003344"/>
    <dbReference type="EnsemblBacteria" id="EEZ42311">
        <property type="protein sequence ID" value="EEZ42311"/>
        <property type="gene ID" value="VDA_003344"/>
    </dbReference>
    <dbReference type="GeneID" id="57340211"/>
    <dbReference type="eggNOG" id="COG2003">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1833204at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08071">
        <property type="entry name" value="MPN_DUF2466"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025657">
        <property type="entry name" value="RadC_JAB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001405">
        <property type="entry name" value="UPF0758"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020891">
        <property type="entry name" value="UPF0758_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30471">
        <property type="entry name" value="PTHR30471"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04002">
        <property type="entry name" value="RadC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00608">
        <property type="entry name" value="radc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01302">
        <property type="entry name" value="UPF0758"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="MPN" evidence="7">
        <location>
            <begin position="102"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ42311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="224" mass="24998" checksum="7E12CCC93264FCCB" modified="2010-01-19" version="1">MSLKLLPNESLPREKLLARGAQALTDAELLAIFLRTGIAGMNAIELADFLLKEFGSLRALLSADQKTFCQHKGLGPAKYAQLQAVIAMNERHLEETLKRFDVLSSPQQTRNYLSHKLRDQHREVFFVLFLDNQHRVICGEALFFGTIDSASVYPREIVKRSLELNAAAAILAHNHPSGVAEPSQADRRITQKISDALALVDIRVLDHFVIGDGELVSFAERGWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1J3</accession>
    <name>D0Z1J3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Type IV pilus biogenesis protein PilQ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_003407</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 8">Cell outer membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the bacterial secretin family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003407"/>
    <dbReference type="EnsemblBacteria" id="EEZ42374">
        <property type="protein sequence ID" value="EEZ42374"/>
        <property type="gene ID" value="VDA_003407"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4796">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001775">
        <property type="entry name" value="GspD/PilQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005644">
        <property type="entry name" value="NolW-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038591">
        <property type="entry name" value="NolW-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013355">
        <property type="entry name" value="Pilus_4_PilQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011662">
        <property type="entry name" value="Secretin/TonB_short_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004846">
        <property type="entry name" value="T2SS/T3SS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00263">
        <property type="entry name" value="Secretin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03958">
        <property type="entry name" value="Secretin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07660">
        <property type="entry name" value="STN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00811">
        <property type="entry name" value="BCTERIALGSPD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00965">
        <property type="entry name" value="STN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02515">
        <property type="entry name" value="IV_pilus_PilQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="domain" description="STN" evidence="9">
        <location>
            <begin position="194"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ42374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="583" mass="63668" checksum="6433CDDBD1D3DDE6" modified="2010-01-19" version="1">MMEEANLRMKRMLSVNLGWQRCWVVMLCCWLGLSQAAIAAGMNIVNNQITGLDFKRDNRGRGVLTVQLAKPQSLVDMRRSGKQLHIDIFDTAIKDDMLYVLDVVDFATVVRSIETFRTEKGSKLILNMAGVFDYDYQLKGSRLEVVLNAQKKKASSTAKAKQGKIDYKGKPISINFQDVPVRNVLQLVAEYNDFNLVVSDTVQGNVTLRLDDVPWPQVLDIILQSKGLDKRVQGSVVLIAPKSELATNERQEMEAKRKEDELASLRSELIQINYAKAGDIADLLLGTKDGVSMLSQRGSLHVDERTNAIIIKDIPESIDSIEEIITALDIPVKQVQIEARIVTVDEGDIDELGVRWGVVNQNGSTTIGGSIEGNLASSGLLGDDATVDDFLNVNLGAITPGASSIAFQVAKLGDILLDLELSALQAESKAEIISSPRLVTTNKKAAYIEQGTEIPYLEAASSGAVSVDFKKAVLSLMVTPQITPDDKLVLDLLVTQDKVGETVVTGTGEAVAIDTQRIGTQVLVNNGETVVLGGIYQHQVNNSVRKVPLLGDIPGLGVLFRHKLQEMGKRELLIFVTPKIITQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1K7</accession>
    <name>D0Z1K7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF1338 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003421</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302677.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003421"/>
    <dbReference type="EnsemblBacteria" id="EEZ42388">
        <property type="protein sequence ID" value="EEZ42388"/>
        <property type="gene ID" value="VDA_003421"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5383">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="714422at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009770">
        <property type="entry name" value="DUF1338"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07063">
        <property type="entry name" value="DUF1338"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01150">
        <property type="entry name" value="DUF1338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1338" evidence="1">
        <location>
            <begin position="4"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="268" mass="30329" checksum="79DA28F8A24503F5" modified="2010-01-19" version="1">MERAQLLFSQLWQDYITRLCPSAEKVQQLLTEDDPLMNDHIALRTYNLPRCGLDRVAAAFIAVGYEPKGQYKFEEKKLYAEHFEHPNPVLPKVFISELQLGQCSSQLQLLVRKLLDQVPHGYFSNSMFLSQGRPWTLSYQEYQMLAQESEYAAWVAAHGFGANHFTVSINPLEQFTEVAEVNHYLTHNGFAINQAGGAVKGSAALMLEQSSTMADKVMVEFSDGKQLIPGGFYEFAKRYPMANGDLFSGFVEASANRIFESTYQNNEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1M6</accession>
    <name>D0Z1M6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">50S ribosomal protein L4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplD</name>
        <name evidence="7" type="ORF">VDA_003440</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Forms part of the polypeptide exit tunnel.</text>
    </comment>
    <comment type="function">
        <text evidence="5">One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uL4 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302784.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003440"/>
    <dbReference type="EnsemblBacteria" id="EEZ42407">
        <property type="protein sequence ID" value="EEZ42407"/>
        <property type="gene ID" value="VDA_003440"/>
    </dbReference>
    <dbReference type="GeneID" id="57340103"/>
    <dbReference type="eggNOG" id="COG0088">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1572673at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01328_B">
        <property type="entry name" value="Ribosomal_L4_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002136">
        <property type="entry name" value="Ribosomal_L4/L1e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023574">
        <property type="entry name" value="Ribosomal_L4_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013005">
        <property type="entry name" value="Ribosomal_uL4/L1e"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10746">
        <property type="entry name" value="PTHR10746"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00573">
        <property type="entry name" value="Ribosomal_L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52166">
        <property type="entry name" value="SSF52166"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03953">
        <property type="entry name" value="rplD_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="42"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ42407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="200" mass="21842" checksum="D04266F2A79E043B" modified="2010-01-19" version="1">MELVVKGANALTVSETTFGRDFNEALVHQVVVAYAAGARQGTRAQKTRSDVSGGGAKPWRQKGTGRARSGTMRSPIWRKGGVSFAARPQDHSQKVNKKMYRGAMKSILSELVRQERLIVVENFSVEAPKTKALVAKLNELELTDALIVTGELDENLFLAARNLYKVDVRDAKAIDPVSLIAFEKVVMTADAVKAVEEMLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1S5</accession>
    <name>D0Z1S5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">SEC-C motif domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_003489</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303588.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ42456">
        <property type="protein sequence ID" value="EEZ42456"/>
        <property type="gene ID" value="VDA_003489"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3012">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1973829at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004027">
        <property type="entry name" value="SEC_C_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02810">
        <property type="entry name" value="SEC-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ42456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="284" mass="33523" checksum="5BCA472537F05099" modified="2010-01-19" version="1">MNLLQRKKLFQKTTTEIKASLVNFSKRRHTRQNEAIFLKKIENVRLRLVEGGLQEDAKELWILKTIYLAQNNYIDFISLLKKKKYYEAWCVLERCEINLKNLMKHIPNEYIEQLHVDFLVHQVPLWQEVYPYKIFASSEFLEKKIRCSECKQLITPRSSCSHLVGEVYNGKLCYRIIEDMEILGIAMVPNPVQKICVPFKKSENGEDVAHYNYQPLDMIVDGLPTLFYWWEINHTIDMQPRSNFDHMETNELCPCGSGRQFIICCSSKEFVLTPHKEIVPLKVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1Z3</accession>
    <name>D0Z1Z3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001979</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299076.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001979"/>
    <dbReference type="EnsemblBacteria" id="EEZ40947">
        <property type="protein sequence ID" value="EEZ40947"/>
        <property type="gene ID" value="VDA_001979"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1328">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="411660at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016905">
        <property type="entry name" value="Glycyl_radical_YjjI-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11230">
        <property type="entry name" value="DUF3029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028991">
        <property type="entry name" value="Glycl_rad_HI0521_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04040">
        <property type="entry name" value="glycyl_YjjI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="514" mass="57563" checksum="819C8EC5C3E2B247" modified="2010-01-19" version="1">MNFSDKFKKIATDPRLTPKQKTLFLSLEADSAIEYPAISAEVEKAMADGIICDMFEGHAPFKPRYVLPDYSKFLTNGSIYLQLPPAEDLDDALNALTIIYHHVPSVTNYPVYLGQLDEMLLPYTQDVSTDELYKKLKRFWIMLDRTLPDAFMHVNIGPTDNIVCRTILQIDAELKQVAPNLTLMYDPDITPDSLLELAVKNICECSKPHIANYPIHKQTFDEQGFGIVSCYNALPLAGGANTLVRMNLKEVAKKSNSIREFFASDLPTYCQTMFELIDARCEFLHKESHFFESSFLVQEELIYPERFAPMFGIYGMAEAVAELLAKENSQAVYGYDDEANQLGLQISAALSDIVTSTPVKYGYQGHALLHSQGGISCDHNVTPGIRIAYGNEPDPVTHIQSLAAQHQYYHSGVSEILTIDQTIKGNPQALMQLCKGSFQLGFREFTANVASNDLVRITGYMVKLSDIAKYEEQGSRTNTTWLGADASVNTDVMQRLPRVLSGEQMPSYHLVDKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z201</accession>
    <name>D0Z201_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Hypothetical ToxR-regulated lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_001987</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299101.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001987"/>
    <dbReference type="MEROPS" id="M66.001"/>
    <dbReference type="EnsemblBacteria" id="EEZ40955">
        <property type="protein sequence ID" value="EEZ40955"/>
        <property type="gene ID" value="VDA_001987"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502Z7RH">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="43842at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019503">
        <property type="entry name" value="Peptidase_M66_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022218">
        <property type="entry name" value="TagA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12561">
        <property type="entry name" value="TagA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51694">
        <property type="entry name" value="PEPTIDASE_M66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018775" evidence="7">
        <location>
            <begin position="22"/>
            <end position="946"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M66" evidence="8">
        <location>
            <begin position="405"/>
            <end position="661"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ40955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="946" mass="104381" checksum="56CDFFE03C90470B" modified="2010-01-19" version="1">MKKKTIALFILASLYGATASAESLTLEASTNKVMQKMNELAELAKDPANVIQKGDQKYLSYKGKELRINFDGNIKFDLMDFHSEFNTVFDFIPSAWETYWYDGGFDIYPGKSDECKFELFAAARGSKDNEGNYSWERPLSTVLTTTGCPDVTQKESIFFNTNTVTNDLSGNLAGAVLFAQAHIVPANANEQEKRMHLVGERKTKVMLKPENELDYYSTVTVTATDKAGQVLGEIEMKNPSQLAPNVLSMPELTTTNIDFSYDESKAFNVSTPTTEAIAAALVDHDTVVMRTWNGHWNRMFDLEQDNPKLDGKTFVFISSAGYNSHVNYYKDRSRTIVNGTTTVFKNVNGAWILQDDLIFNEIGYAQGYWSADLPKEWLKPGLALSFANGDKKGTLNSIKVGAPTELLINTIDVGMLVEPRGRFDFQKDKEVQREYFETAPVSKMIVNEYEPVHLTEVMLPDGTLLTDHDPSDGGWHGGTMRQRIGKELISIGINNANYGIYSSSGVGEGENPYIAAQLTAHNTRGMYNNGLQTHGGSGGAGMVTLDSSIGNEFSHEVGHNYGLGHYPGGFAGSIHRPADMLNSTWGWDSSKNVFIPNFSPINTGGESCLDGQCVPAFNGMFKYGSDAMAGGWAMYGAQRFTMYTPYSMYFIQKNLESKVVFDKTSSTGFRKWDEATQTMAEYTHRIENMEVTSVNPWDANETKIAALFENFDKVDLSTWNGHWARNMSVPAASEINKGKVFTFNSSAGYNSHLAINGQEMLVPYGSRLTFVSDGQTWVKDAPFESTKAVHPEKYGVPVTTLVGYYDPQAKLDSYIFPALHGAFGYVYSDDSADLIAGQCALEVETQSGSVLKYALKNNRRNADNMNKFHVNVATSDNPVSASVVCDGQVLDTRTIDAPKLAPIYTVQGGDAKARSAAAFFSAPVPRVEATRYEPQACNHADGEHNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2A8</accession>
    <name>D0Z2A8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000559</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304722.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000559"/>
    <dbReference type="EnsemblBacteria" id="EEZ39539">
        <property type="protein sequence ID" value="EEZ39539"/>
        <property type="gene ID" value="VDA_000559"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5033RTU">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1654302at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11530">
        <property type="entry name" value="NTP-PPase_DR2231_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3420.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033653">
        <property type="entry name" value="NTP-PPase_DR2231-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023292">
        <property type="entry name" value="NTP_PyroPHydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021130">
        <property type="entry name" value="PRib-ATP_PPHydrolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01503">
        <property type="entry name" value="PRA-PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="192" mass="22003" checksum="3E3E681948607BE2" modified="2010-01-19" version="1">MKLTVLDQPLYDHLYRDIREFRETFDLAIEAPESLNEQSDTLHTSLAVEEMTELAEADSLVEQADAIVDSVYVLMGRLVHLGDKQVSDNLGISYLIDLLLQIAQRLNIDFVACWDEIHSSNMSKVCRNQQEFDDTQAHYAKQNIEVTSTPKGEYLIVKCAKDVELEDKIIRQGKVLKSLYYRPADLVKLVIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2I3</accession>
    <name>D0Z2I3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">L-aspartate oxidase</fullName>
            <ecNumber evidence="4">1.4.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">VDA_000634</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-aspartate + O2 = H2O2 + iminosuccinate</text>
            <dbReference type="Rhea" id="RHEA:25876"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:77875"/>
            <dbReference type="EC" id="1.4.3.16"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:25877"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; NAD(+) biosynthesis; iminoaspartate from L-aspartate (oxidase route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.16" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304929.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000634"/>
    <dbReference type="EnsemblBacteria" id="EEZ39614">
        <property type="protein sequence ID" value="EEZ39614"/>
        <property type="gene ID" value="VDA_000634"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1053">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="153138at2"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00326"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008734">
        <property type="term" value="F:L-aspartate oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044318">
        <property type="term" value="F:L-aspartate:fumarate oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.700.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-binding_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037099">
        <property type="entry name" value="Fum_R/Succ_DH_flav-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015939">
        <property type="entry name" value="Fum_Rdtase/Succ_DH_flav-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005288">
        <property type="entry name" value="NadB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027477">
        <property type="entry name" value="Succ_DH/fumarate_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42716">
        <property type="entry name" value="PTHR42716"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02910">
        <property type="entry name" value="Succ_DH_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46977">
        <property type="entry name" value="SSF46977"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_2" evidence="11">
        <location>
            <begin position="15"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="Succ_DH_flav_C" evidence="12">
        <location>
            <begin position="449"/>
            <end position="538"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ39614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="554" mass="61891" checksum="5DA2BA770750065A" modified="2010-01-19" version="1">MQQQLAVTKIYETEALVIGSGIAGLVSCFNLLQHSCQTVLTTDKKLAGGASFSSIKGSLGIQVTDNDAQDIELFKKDLTRIGVGMDNPELIDTYVQQSPKSIVELQNIGFKPWLRSDRRPACFADYPRDIYLINDWRQAKDNAKKIFNHPNLQLLEEHRLLTILTENKVAIGALFITATNDYLLIKSNNIVLACGGIGGLYQHSLYPAEVNGSGHLAALDAGAKLVNMEFIQFIPALVTPKYNTLFGEHTAKYCTKLVDEFNQNLLLHIPQEQQQSLWQEYSGYAPFSCDFPSHIIDLAIFKAISSGSQFAKMSFSEKLYHDTQEFYTLYLNWLESLGINMCRDEIGIAHFAHSCNGGIQISTEGETTVSGLYAVGEISSAIEGANRLGGNSVGGALVFAKRAADHIKSKKHKPLIGNELLLSKFHHWYHKVINSDNNDSIRSPREISHQIQAILAASANIVRSHTQLQCALDQIDSLTKQFSIAEHQTYLGFNALSNLRMAKVLLSCMLERTESRGAHYREDFPQRDPSSYRIEISMSQNNDIELNKIFRSYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2P9</accession>
    <name>D0Z2P9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000700"/>
    <dbReference type="EnsemblBacteria" id="EEZ39680">
        <property type="protein sequence ID" value="EEZ39680"/>
        <property type="gene ID" value="VDA_000700"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5030NDG">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="79" mass="8958" checksum="18C7B149FF64211C" modified="2010-01-19" version="1">MQCWFEAKNVVCQAGYSDGSTAVDYDVDMFDYDDNLIAKVKTDKGSRAVFTHPETDFYLVFDAGHENPVEVDVVEIKEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2Q9</accession>
    <name>D0Z2Q9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">Chaperone protein DnaK</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">HSP70</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Heat shock 70 kDa protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Heat shock protein 70</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">dnaK</name>
        <name evidence="10" type="ORF">VDA_000710</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Acts as a chaperone.</text>
    </comment>
    <comment type="induction">
        <text evidence="7">By stress conditions e.g. heat shock.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305125.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000710"/>
    <dbReference type="EnsemblBacteria" id="EEZ39690">
        <property type="protein sequence ID" value="EEZ39690"/>
        <property type="gene ID" value="VDA_000710"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0443">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="161217at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00332">
        <property type="entry name" value="DnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012725">
        <property type="entry name" value="Chaperone_DnaK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="PTHR19375"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="SSF100920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02350">
        <property type="entry name" value="prok_dnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword evidence="5 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="596"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="596"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphothreonine; by autocatalysis" evidence="7">
        <location>
            <position position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ39690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="631" mass="68310" checksum="A667AE3D2385BA21" modified="2010-01-19" version="1">MSKIIGIDLGTTNSCVAVLDGDTARVIENAEGERTTPSVIGYTDTETLVGQPAKRQAITNPENTLFAIKRLIGRRFEDEEVQRDLKIMPYHIVKADNGDAWVEAKGQKLAAPQISAEVLKKMKKTAEEYLGEPVTGAVITVPAYFNDAQRQATKDAGRIAGLDVKRIINEPTAAALAYGLDKKGGDRTIAVYDLGGGTFDISIIEIDEVEGEKTFEVLATNGDTHLGGEDFDNRVINYLVDEFKKEQGIDLRNDPLAMQRVKEAAEKAKIELSSAQQTDVNLPYITADATGPKHMNIKMTRAKLESLVEDLVQRTLDPLKAALEDANLTANDITDVILVGGQTRMPLVQAKVTEFFGKEPRKDVNPDEAVAMGAAVQGGVLAGDVKDVLLLDVTPLSLGIETMGGVMTKLIEKNTTIPTKANQVFSTAEDNQTAVTIHVLQGERKQAMNNKSLGQFNLEGIQAGPRGMAQIEVTFDLDADGILNVSAKDKATGKEQKITIQASSGLSEAEIEKMVQEAEANKEADKKFEELVTARNQADHLIHTARKQIDEAGDNLAADVKTSVENAIKELEEAKSSDDKARIDSATQTLTAAMQKVMEQAQASSQAQSGTDADQKAKDDDVIDAEFEEMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2W4</accession>
    <name>D0Z2W4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Bifunctional NAD(P)H-hydrate repair enzyme</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Nicotinamide nucleotide repair protein</fullName>
        </alternativeName>
        <domain>
            <recommendedName>
                <fullName evidence="16">ADP-dependent (S)-NAD(P)H-hydrate dehydratase</fullName>
                <ecNumber evidence="16">4.2.1.136</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="16">ADP-dependent NAD(P)HX dehydratase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="16">NAD(P)H-hydrate epimerase</fullName>
                <ecNumber evidence="16">5.1.99.6</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="15" type="primary">nnrE</name>
        <name evidence="14" type="synonym">nnrD</name>
        <name evidence="18" type="ORF">VDA_000765</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13 16">Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.</text>
    </comment>
    <comment type="function">
        <text evidence="14">Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.</text>
    </comment>
    <comment type="function">
        <text evidence="15">Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 15 16">
            <text>(6R)-NADHX = (6S)-NADHX</text>
            <dbReference type="Rhea" id="RHEA:32215"/>
            <dbReference type="ChEBI" id="CHEBI:64074"/>
            <dbReference type="ChEBI" id="CHEBI:64075"/>
            <dbReference type="EC" id="5.1.99.6"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 15 16">
            <text>(6R)-NADPHX = (6S)-NADPHX</text>
            <dbReference type="Rhea" id="RHEA:32227"/>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
            <dbReference type="ChEBI" id="CHEBI:64077"/>
            <dbReference type="EC" id="5.1.99.6"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 14 16">
            <text>(6S)-NADHX + ADP = AMP + H(+) + NADH + phosphate</text>
            <dbReference type="Rhea" id="RHEA:32223"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:64074"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.2.1.136"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 14 16">
            <text>(6S)-NADPHX + ADP = AMP + H(+) + NADPH + phosphate</text>
            <dbReference type="Rhea" id="RHEA:32235"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.2.1.136"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15 16">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
        <text evidence="15 16">Binds 1 potassium ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="14">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the NnrD/CARKD family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the NnrE/AIBP family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 16">In the C-terminal section; belongs to the NnrD/CARKD family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 16">In the N-terminal section; belongs to the NnrE/AIBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.136" evidence="16"/>
    <dbReference type="EC" id="5.1.99.6" evidence="16"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305282.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000765"/>
    <dbReference type="EnsemblBacteria" id="EEZ39745">
        <property type="protein sequence ID" value="EEZ39745"/>
        <property type="gene ID" value="VDA_000765"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0062">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0063">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052855">
        <property type="term" value="F:ADP-dependent NAD(P)H-hydrate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052856">
        <property type="term" value="F:NADHX epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052857">
        <property type="term" value="F:NADPHX epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046496">
        <property type="term" value="P:nicotinamide nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01171">
        <property type="entry name" value="YXKO-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01965">
        <property type="entry name" value="NADHX_dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01966">
        <property type="entry name" value="NADHX_epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017953">
        <property type="entry name" value="Carbohydrate_kinase_pred_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000631">
        <property type="entry name" value="CARKD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030677">
        <property type="entry name" value="Nnr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004443">
        <property type="entry name" value="YjeF_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036652">
        <property type="entry name" value="YjeF_N_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01256">
        <property type="entry name" value="Carb_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03853">
        <property type="entry name" value="YjeF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017184">
        <property type="entry name" value="Nnr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64153">
        <property type="entry name" value="SSF64153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00196">
        <property type="entry name" value="yjeF_cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00197">
        <property type="entry name" value="yjeF_nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01050">
        <property type="entry name" value="YJEF_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51383">
        <property type="entry name" value="YJEF_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51385">
        <property type="entry name" value="YJEF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 14 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11 15 16" id="KW-0413">Isomerase</keyword>
    <keyword evidence="12 14 16" id="KW-0456">Lyase</keyword>
    <keyword evidence="15 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 14 16" id="KW-0520">NAD</keyword>
    <keyword evidence="9 14 16" id="KW-0521">NADP</keyword>
    <keyword evidence="7 14 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15 16" id="KW-0630">Potassium</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YjeF N-terminal" evidence="17">
        <location>
            <begin position="13"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="NADPHX" evidence="15">
        <location>
            <begin position="61"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="NADPHX" evidence="15">
        <location>
            <begin position="129"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="255"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="316"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="362"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="399"/>
            <end position="403"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="427"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="428"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00009524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00025153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRNR" id="PIRNR017184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EEZ39745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="489" mass="51952" checksum="B33BB096D490D4C5" modified="2010-01-19" version="1">MADVVAFYDTEQVKIGEQGIANELKITMYELMQKAGTAVFQAIVQSYPDAHSLIIFVGKGNNGGDGYVVARLALLAGYGVQVHHHGDQNRLTSDSHKAKQDYLNAGGFLLAYDDLDFQNIDLVIDALLGTGLNGNVYPETCALIHKINHLNLPIMSIDIPSGLCANTGFASKEVIKADTTVCLIAIKSGLITGSAREYVGKLVLDDLGVKTPFCKNAFVKGILTYAKIKLRKPTYHKGNSGHSLVIGGDAGMGGALLLSSEACLRSGAGLVASLTDTTNIMPSLVRTPEVMASDWQNQEMLSQRLSWATALGFGPGLGLSSFAKYLFIQITQQTLPKVFDADALNILSLTPNFDDLRILTPHPGEAARLLNCTIKDIEQDRYQAVQKIQSKYGGVVVLKGAGTVIYDGKQFFVCAIGNASMATGGMGDVLTGVITSLLAQGYNTTQAAVYGVHIHSLAGDLAAKTKPIGLIASDVIAYLSNAVYLSSNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z300</accession>
    <name>D0Z300_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alkylphosphonate utilization operon protein PhnA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000801</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305389.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39781">
        <property type="protein sequence ID" value="EEZ39781"/>
        <property type="gene ID" value="VDA_000801"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2824">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1507972at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013991">
        <property type="entry name" value="PhnaA_N_proteobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004624">
        <property type="entry name" value="YjdM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013988">
        <property type="entry name" value="YjdM_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30305:SF3">
        <property type="entry name" value="PTHR30305:SF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03831">
        <property type="entry name" value="YjdM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00782">
        <property type="entry name" value="PhnA_Zn_Ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PhnA_Zn_Ribbon" evidence="1">
        <location>
            <begin position="6"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="191" mass="20935" checksum="68C670DDE1D82248" modified="2010-01-19" version="1">MTIEQALKDRSGNKCELCSSEDNLHVHNVAASADKSAGCCVYLCDTCSTQIENPEATDENHWRCLNDSMWSQVPAVQVMAYRQLKRLSTTTDWAMDLVDMMYLEDDVREWAEKGLVAEAEAAVPTLDSNGAALQAGDTVTIIKDLPVKGSSMVIKRGTAVRNISLTDNPLHIQGRADGVQMVIIAAYTKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z366</accession>
    <name>D0Z366_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative thiol-disulfide isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000867</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305575.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000867"/>
    <dbReference type="EnsemblBacteria" id="EEZ39847">
        <property type="protein sequence ID" value="EEZ39847"/>
        <property type="gene ID" value="VDA_000867"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1651">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1805428at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012640">
        <property type="entry name" value="Membr_lipoprot_lipid_attach_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041205">
        <property type="entry name" value="ScsC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08139">
        <property type="entry name" value="LPAM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18312">
        <property type="entry name" value="ScsC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13462">
        <property type="entry name" value="Thioredoxin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Thioredoxin" evidence="3">
        <location>
            <begin position="64"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="261" mass="28925" checksum="AAA6B50BE78127D4" modified="2010-01-19" version="1">MKKYLLPLFITAALTGCNDSQANNASSADFSSAQKAQIEKIASDYIIAHPEILVKASETLQKQQMEQQQQAAVSAIIQNTDKLINDKATPFVGPKDAKVNVIEFFDYQCMYCSKIAPVVKELQKANPNVRFIFKETPIFANRWEASKYAADMGNWIFEQKGSAAYEQYHNAIFATRKDEGNLTKVDVDTAAKSVGVDTTKMNLDNSFMQNFKLFSELGFQGTPALIVMPTENANKDNVKVINGFDPQGLKNAIADLTAKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z377</accession>
    <name>D0Z377_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">VDA_000878</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305608.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000878"/>
    <dbReference type="EnsemblBacteria" id="EEZ39858">
        <property type="protein sequence ID" value="EEZ39858"/>
        <property type="gene ID" value="VDA_000878"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004721">
        <property type="term" value="F:phosphoprotein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Histidine kinase" evidence="9">
        <location>
            <begin position="218"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="10">
        <location>
            <begin position="456"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="8">
        <location>
            <position position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ39858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="570" mass="64639" checksum="48D572F1D0EE7FD1" modified="2010-01-19" version="1">MDEPYLRLLQKKINRERKARITAEKLLEEKSLELYEAKRLIEDSAEKIKHQAKLDSQLLAYQTQMENHLLYYSQLFLKQEPTPSILNHLVEQLIDNRYVSSCCIFIQTDSDTSLEGLYQAGNIDLWSFHSNLNIQTKYWDHKNKILWLSLTHNHQIIGHFAAQISSTSASLKTLQQHLILFKELLCSALGRKISMNNAISAQKRAENSERSTRDFLAMINHELRTPLNGLLGAAELLADTSLSSEQKKLLDTLNNSGELLRAIINDLLDYSKISAGMLELIIKPFNPHQIINNLADIMRYQAQEKQLLLTLVIDNTVPNCLLGDEDRIKQIFVNLINNAIKFTNRGSIILNTTWCEDKLIFQVKDTGIGITEGQQLKLFKPFSQVDISSQRIHEGTGLGLAICKQLCELMSGEIKLISIPEQGSTFTVILPLKLCDTPLDISQQTIKPTQLSSQKKVLVVEDLATNQMIIKLMLTKLGIEPKIVNNGQEAIDIISNTSFDIILMDCRMPVMDGYTATRLLRNNGYTKPIIALTAGTTTTEREECLTSGMDDILCKPYQRAELHKMLMKWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-06-02" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z382</accession>
    <name>D0Z382_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000883</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305623.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000883"/>
    <dbReference type="EnsemblBacteria" id="EEZ39863">
        <property type="protein sequence ID" value="EEZ39863"/>
        <property type="gene ID" value="VDA_000883"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3672">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1500682at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010319">
        <property type="entry name" value="Transglutaminase-like_Cys_pept"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39327">
        <property type="entry name" value="PTHR39327"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06035">
        <property type="entry name" value="Peptidase_C93"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018867" evidence="1">
        <location>
            <begin position="22"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="223" mass="25695" checksum="8BDF818D255D8757" modified="2010-01-19" version="1">MKKFVTLVAVALLCIAANVDALTSREQQQISKIRSFYGERAEKRATAWRELIDKSRQFPVQKQLKLVNDFFNQFIFVDDIKLWGKKDYWATPLEFVGVGAGDCEDFSIAKYMALRSLGVPDSKLRLVYVKSLTLNQFHMVVAYYPTPTAVPEILDNLDGEIKPANKRKDLLPIYSFNGSNLWLIKQQGQGQLAGKASRLSMWNDLRHRNRKIELHRPKINFDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z385</accession>
    <name>D0Z385_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Lipoate--protein ligase</fullName>
            <ecNumber evidence="4">6.3.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_000886</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(R)-lipoate + ATP + L-lysyl-[lipoyl-carrier protein] = (R)-N(6)-lipoyl-L-lysyl-[lipoyl-carrier protein] + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:49288"/>
            <dbReference type="Rhea" id="RHEA-COMP:10500"/>
            <dbReference type="Rhea" id="RHEA-COMP:10502"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.1.20"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein lipoylation via exogenous pathway; protein N(6)-(lipoyl)lysine from lipoate: step 1/2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein lipoylation via exogenous pathway; protein N(6)-(lipoyl)lysine from lipoate: step 2/2.</text>
    </comment>
    <dbReference type="EC" id="6.3.1.20" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305632.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000886"/>
    <dbReference type="EnsemblBacteria" id="EEZ39866">
        <property type="protein sequence ID" value="EEZ39866"/>
        <property type="gene ID" value="VDA_000886"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0095">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="871298at2"/>
    <dbReference type="UniPathway" id="UPA00537">
        <property type="reaction ID" value="UER00594"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016979">
        <property type="term" value="F:lipoate-protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009249">
        <property type="term" value="P:protein lipoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004143">
        <property type="entry name" value="BPL_LPL_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019491">
        <property type="entry name" value="Lipoate_protein_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004562">
        <property type="entry name" value="LipoylTrfase_LipoateP_Ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12561">
        <property type="entry name" value="PTHR12561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03099">
        <property type="entry name" value="BPL_LplA_LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10437">
        <property type="entry name" value="Lip_prot_lig_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00545">
        <property type="entry name" value="lipoyltrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51733">
        <property type="entry name" value="BPL_LPL_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BPL/LPL catalytic" evidence="8">
        <location>
            <begin position="29"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ39866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="338" mass="38469" checksum="EBDE7AE2E3C0892B" modified="2010-01-19" version="1">MSSLRVFISTSTDPWFNLAVEDSIFHAMAPNQRVLFLWRNNNTVVIGRAQNPWKECNTHKMESDHIKLARRQSGGGAVFHDLGNTNFTFMAGKPEYNKSISTQIVIDALQTLGINAIATGRNDLVIEDDDGTRKFSGSAYRETLDRGFHHGTLLLNADLNRLANYLNPDPKKLQAKGITSVRARVTNLSNINPSIDHQSVSTAITQAFFEYYGEHVELELISPEKMPNIPGFEERYKKQKSWEWNFGNTPQFMHSLDERFTWGGVELHFDVEKGNISKVQVFTDSLTPDVIEFFANKLVLAPYKEDTITQAIEVTQKQYPAHHDELKQLQDWLVKAIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3A0</accession>
    <name>D0Z3A0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Metal transporting ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_000901</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305674.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000901"/>
    <dbReference type="EnsemblBacteria" id="EEZ39881">
        <property type="protein sequence ID" value="EEZ39881"/>
        <property type="gene ID" value="VDA_000901"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2217">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="237367at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027256">
        <property type="entry name" value="P-typ_ATPase_IB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01525">
        <property type="entry name" value="ATPase-IB_hvy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-1278">Translocase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="687" mass="75122" checksum="D9FA5919CE252F74" modified="2010-01-19" version="1">MISIQVKHHFPGRIRFKVPSLRFHQGVGSWIETSLLAIQGISDVRVNESAYSVVIEYDTQLLHAKVVEERLNQLDLSNATIDSDPEHKFTRGDIAMNVIGTIAAALLPSKWGTLSTAVLIAPTLFAGARDLKEKKVSVEVLDAIAVGLSAWRKDYRTAMMTQSLISLGEYMEQKTSRNSDQLLADLMRPQESIVWRIQNGTRSQINSTELEVADVIELSPGVSIPVDGTIIKGTALVNQSSLTGENVPVRREEGAFVYSGTSIHEGTIQVRVDKVGSEATTAKIAKLIYDSLSEKSEIQQVTQDMANRRVKITLGIGAAVFALTQDINRVASVFLVDYSCALKLSTPVTFKSIMYRAAQQGILFKGGSAIEKLVNIDTCVFDKTGTLTHGDMQVTDVIPLCESNSARDLLAIAASVEEHSNHPLSQAVVNAAKHNQLPHIEHGEVEYVIAHGLRSTLNEHELVMGSRHFLEVHENVDFSSFEQIIREYEAKGRHLIFISHQNILIGMIGLRDHLREDALETLSILRQFGVKELIMVTGDSKFKASILAEELKLDRVFAEAVPSEKSTIVESLQASGRKVMFVGDGVNDAPALTAADVGVAMCRGTELARQVADVVLLRDQLHGLAEAKELADIAMNVINSNIKIAEYVNSGIMLAAAMGWLSPTMSALLHNGTTLSILSRSASLKYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3A7</accession>
    <name>D0Z3A7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_000908</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000908"/>
    <dbReference type="EnsemblBacteria" id="EEZ39888">
        <property type="protein sequence ID" value="EEZ39888"/>
        <property type="gene ID" value="VDA_000908"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0503">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1040">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041047">
        <property type="entry name" value="LPD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040561">
        <property type="entry name" value="LPD38"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040651">
        <property type="entry name" value="LPD5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18796">
        <property type="entry name" value="LPD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18857">
        <property type="entry name" value="LPD38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18799">
        <property type="entry name" value="LPD5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LPD5" evidence="3">
        <location>
            <begin position="1148"/>
            <end position="1295"/>
        </location>
    </feature>
    <feature type="domain" description="LPD1" evidence="2">
        <location>
            <begin position="1449"/>
            <end position="1535"/>
        </location>
    </feature>
    <feature type="domain" description="LPD38" evidence="4">
        <location>
            <begin position="2395"/>
            <end position="2602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="401"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="499"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="806"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="912"/>
            <end position="983"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1751"/>
            <end position="1770"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1993"/>
            <end position="2023"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="411"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="432"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="499"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="806"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="916"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="966"/>
            <end position="983"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF18799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF18857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="2710" mass="300100" checksum="F7C1FCB571D7A945" modified="2010-01-19" version="1">MNDQLLGDDVAPKATVNAKTDMTTFSKQDLGNSGLPAEPNYEVGISDIGKSTLSAGLRSISGIAEIGNQNVKALENKANKDDGFVSGIANAMTYVPIIPIADKVLPKLRDGLSSVANSIDNTLSSDAKKAAQTMPVTKEGDEWRFSSDPAVFGMNFANVVGYMLPTVATAFATRGQSLAALEPALTRAMIRTGASKAVAEKALPYVVNALKSAPATTAGITSDLGSQGNDMRRQALDSNFDQLSESKYFREAFSDIDSNPETASLTDGQKLSLARERVADFASRATISDPKNIAASAAATMLGDVPLANAALKGLKTTAGGLRGAAHGFISGGLREAPLEGMQEGIQQKVSNNVSNQYLGSDIDPNQGVDKARANGALLGFLSGGSLNAIGGLRGEHEQAIEPETQTGETGSPDKVDEEPETTPVDVSVTRDLNEEPQDKPTHAQHGYTKEEAVDDLNAPAYLREELRNQAGPQPDLNTGQSYDVDDLSIPAYLRNGKEINEDPETHERVSEPNTKEQSFSHKEGSVTPKTFDETYLLDDGTTTLDTEHHMKGKNDIVFSDVPPSVIYGHDQRSKVLAQNNDDKQVGYPEFDGGLKKSQRRELEYLARRRADKIPLAMQNLKGAARITRPEYREELVQLADQSSALSHNKEVNHQLDTVTSAITKLGGINRDLAKSEGIDEAHFKRNQLFPTKGGRTFDEMAEVLNEHGFTARSGKSLSANDVLDLVGGELDNNERHYSNQSDAITETDKGSALAELVREYGNERIQIAIKKALKGERLGDRQGDIVNEAMDVIETGRIEQAGGIESRRNERDMRRASRQAKREQKLKQASQDLGLPDWVTSDYSMNLEQEYSDTVESLLDDSIYQASSIDHQATEHLIKEYEAGKLTTAQLISKLGEIDYADQQAVSNMEDAKPITEITDTKSAEERTRTSTLRTEQKAELEHDAGAKETVEQGKQNLGKNKPEPKSTPKTEEGTQEHLDKEISVEPTLSKPHLVKNDIQDVGEKIGGARKDIWESYSSTVEGHTKGELQSLPLSKSWPQPNYQAMLNQGGSLDTLSLFRAIRDSITAKPRSGYKVSRWANNVHSLREVALKVLDGSITKEQADTILKTSTSREAHQIAGRAALYQAMGLNNSLSGFTVSQGEYSLFNGQQFNPPKTIWTVERTTKSNGLNHWPRMMSFGDTQAEAIEKFKHKYQELIDGTKDEPKLATFDIYTKYQTHGYFIGKEVGRSYVDLEGPIDSIKEARRILNEENERLSQKLAREKYVPALRGEENYPRVGEDMRQGSDVSADDFANVFGFRGVEFGNWVDQKKRQTMVNEAYDALMDMAAVLNISPKAISLNGELGLAFGARGIGGKNAAKAHYEPGKVVINLTKKKGAGSLGHEWWHALDNYFGKMDVLKSNPDPQEMMTLRSLKDRKEMVVRAEMRAAFKGVMDVINDSDLVKRSKHLDKTRSKDYWSTPEEMSARSFESYLIAKLADQNVRNDFLANIVKEPEWNDDAKENGSLVNSYPYPNKAESKNIRSSFDHLFNTIEENKFDDGHVMLFSRESFTPESKNSSKGMPVKQARLAVQSWLRQYKGGAGVSIKVVQTQAEAEHILGAKLDGYKINAFYDEVSASVVVVADNIANTKELRKKLRHEILVHHGLRAVVGDTEYGRILKMVYSGLESKHLKPLIHELEQHYNRSDLNSFVEEVLAHVAEKERNTIQQWYDRIVSSIAQALRKVGLMSQSDITKAELHNIVQTLTERIKSVNEWGPGTESPKESGHGRLSRTKFSKTKAADGLFDRDAFLAAVDKVRKITQGTTTTTTAGFDIPTENLKSQTIRKLADKFQVLKALQKNIAQAGGKVDENNDVYLAEELFHGKSENDLRLMKEKYIQPLADKMAKFNINQAKLDEYLIARHAQERNAYIAKINPKFPDGGSGMTNSDAAAKLDEIRQSGKQKQYDELVHIIDAMIAKQRDVIKASGLESNDLVDTWQSHYKHYVPLKGIAKDEPSSARTGKGFSIGGKESKTAKGRQSMAESPSSHAIIDLTEKLIRAQKNEVGNTLLKLVQDNPSPDYWQVFTNEHPDTVPDIVERKNAVTGEKERTVIDRAVPMAMMSDYYFPTKKDGKVYYIKLHDSRLMNAMKNMGPDTSNGVIRTMAKVNRFLATVNTSYNPEFVVGNFARDIQTAFLNLSAEQTRDDGKIKGQKVVKHTIKDIPKAMRAVYASLREKSLDTAQGKEWQSYFEDFMSDGAKTGWFDMKDVDGQAKELDRMVAMASGTTKGRAYKLLSSTTGFIENLNSAVENAVRLSAYVNARKSGISRKKAASLAKNMTVNFNRRGEVGTTLNAMYMFANASVQGSVNFMRTMYGLNGDGKLKWKNLNQAQKIAMGVVAGSFALSFANRNSAGNDEDGQNWFDKVPNYVKERNFIIMKSLLGGEQDGSYWSIPMPYGYNIFALLGSGVESAVNSDYLTKAQVTGNIALATLSSFSPIGLSESNTVTGTILQNVAPTITKPFLDVGLNENFYGGQVYKENMPFGTPLPESSLSKMGTSEHYKYIAKWLNQVTGGSEFRSGGIDVSPDILQYMVGYLGGAALRFADVKVPGLIDRLEGEEVEPSQVAFLSRISGRVMPYEDQQKFYQRRDELMQIADEANSLSGAKRQAFIGQYKQQLKLMSILKSTDKQLKNLRKKRDIIYALNIPPKDKELRIKNVERKMKTVIDDFNFKYPSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3D3</accession>
    <name>D0Z3D3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phage repressor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000934</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000934"/>
    <dbReference type="EnsemblBacteria" id="EEZ39914">
        <property type="protein sequence ID" value="EEZ39914"/>
        <property type="gene ID" value="VDA_000934"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1974">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1933795at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06529">
        <property type="entry name" value="S24_LexA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039418">
        <property type="entry name" value="LexA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015927">
        <property type="entry name" value="Peptidase_S24_S26A/B/C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12844">
        <property type="entry name" value="HTH_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00717">
        <property type="entry name" value="Peptidase_S24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="SSF51306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="20"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="238" mass="26674" checksum="B128198C639F9CF5" modified="2010-01-19" version="1">MPLLVIKIAQKMVMTLGDRIKERRQALELTQEELAQKVAKIVTDMKFSRVSLSNIELGVQNSVKDKVLLALSNFLKCTPEWLVYGTGPISSDKKSDSVSNVQVESALTQQCPLISWVQAGAFTEIREYPESDYQYYPSPVKCGSRTFILRVHGDSMMDRFHEGDLIYVDPDQIEPIHGKFVIAQLEDSAEATFKQLQIVDGQKLLKALNPNYPADMKYIKISGACRLVGTVVAHVKPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3E2</accession>
    <name>D0Z3E2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF58 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000943</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305791.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000943"/>
    <dbReference type="EnsemblBacteria" id="EEZ39923">
        <property type="protein sequence ID" value="EEZ39923"/>
        <property type="gene ID" value="VDA_000943"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1721">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="848990at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002881">
        <property type="entry name" value="DUF58"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01882">
        <property type="entry name" value="DUF58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF58" evidence="1">
        <location>
            <begin position="57"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="315" mass="36240" checksum="12DBCD60115E353E" modified="2010-01-19" version="1">MNQTAMSALLPAHSDGVTLCLAELLQYKNQTVRWLPPAHSIWSQLNGQHVSRHKGRGMNFAEVRPYQPGDDIRSIDWRVTARTGKAHTKLFTEEREQPVMMLIDLSSNMQFGSQLLLKSVQAAHFSSLISWLTITEKDRIGAIIYNGHSLIECKPTARQQGPLRLINALIASHKESLEHIQKPNLVSFAEALKHLHYLCPKGSDIIVISDFYHLYDQDKQRLTQLRHHNRMQFVQIYDPLEQGQTQYRGREYVTDNKRSAWLDFSSKKTRQAIEQSYYQHQEFIEHLAKSLAIPLHKLSAAKTLTHQLTQMGGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3F2</accession>
    <name>D0Z3F2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GMP reductase</fullName>
            <ecNumber evidence="4">1.7.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Guanosine 5'-monophosphate oxidoreductase</fullName>
            <shortName evidence="4">Guanosine monophosphate reductase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">guaC</name>
        <name evidence="9" type="ORF">VDA_000953</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 7">Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4 7">
            <text>IMP + NADP(+) + NH4(+) = GMP + 2 H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:17185"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.7.1.7"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.7.1.7" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305818.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000953"/>
    <dbReference type="EnsemblBacteria" id="EEZ39933">
        <property type="protein sequence ID" value="EEZ39933"/>
        <property type="gene ID" value="VDA_000953"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0516">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="532857at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902560">
        <property type="term" value="C:GMP reductase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003920">
        <property type="term" value="F:GMP reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006163">
        <property type="term" value="P:purine nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00381">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00596">
        <property type="entry name" value="GMP_reduct_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005993">
        <property type="entry name" value="GMPR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015875">
        <property type="entry name" value="IMP_DH/GMP_Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001093">
        <property type="entry name" value="IMP_DH_GMPRt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00478">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000235">
        <property type="entry name" value="GMP_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01305">
        <property type="entry name" value="GMP_reduct_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00487">
        <property type="entry name" value="IMP_DH_GMP_RED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 4 7" id="KW-0521">NADP</keyword>
    <keyword evidence="4 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 4 6" id="KW-0630">Potassium</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IMPDH" evidence="8">
        <location>
            <begin position="9"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="active site" description="Thioimidate intermediate" evidence="4 5">
        <location>
            <position position="186"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="108"/>
            <end position="131"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 6">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 6">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="216"/>
            <end position="239"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000235-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000235-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ39933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="347" mass="37372" checksum="6665F2A5C92F031F" modified="2010-01-19" version="1">MRIEQDLKLGFKDVLFRPKRSTLKSRSQVELTREFTFKHSGRQWSGVPIIAANMDSVGSFAMAQALAKHNVMTAIHKHYTTADWQEFVEQNDASVLNNAMVSTGTSDADFQKTKDIMAMSDDLIFICIDIANGYSEHLVEYVQKVRAQFPNKVISAGNVVTGDMVEELILAGADIVKVGIGPGSVCTTRVKTGVGYPQLSAIIECADAAHGLGGRIIGDGGCSCAGDVSKAFGGGADFVMLGGMLAAHTESGGEVIEQNGKTFMKFYGMSSQSAMDKHSGGVAKYRAAEGKTVLLPFRGPVENTIQDIMGGVRSTCTYVGAAQLKELTKRTTFIRVQEQENNVYGKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3J1</accession>
    <name>D0Z3J1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Galactose operon repressor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_000992</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305931.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000992"/>
    <dbReference type="EnsemblBacteria" id="EEZ39972">
        <property type="protein sequence ID" value="EEZ39972"/>
        <property type="gene ID" value="VDA_000992"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1796334at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00036">
        <property type="entry name" value="HTHLACI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="2"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="330" mass="36660" checksum="1F79E50E6816241C" modified="2010-01-19" version="1">MATIKDVAKAANVSTATVSRVINQSDSVLPETVAKVESVMAQLGYQIKDNRRLTINQGQDTIGLIVSRFHSPFYGLLTQGVEKIAKKHGRKLIVASGNYDIECEEEALKFILSKGCRNIIVHSKAMTDEMLIRYVKQHPGIIIINRHVAEIESQCVWLDNSAGTYLATKHLIEQGHHKIAYLSCEMEVDDKFDRFNGYQQALAEAGIEFNPDWVEEVPFGEPGGAEAAINLLNKGLPVTALVAFNDFYAAAAMQVFKEHGIEIPQRLSIVGFDDVLPQCYFNPKLTTIRSPIESMAMNAARLSLEGCELPVSNTFHPLLIKRDSVQKPFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-02-10" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3M2</accession>
    <name>D0Z3M2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_001023</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001023"/>
    <dbReference type="EnsemblBacteria" id="EEZ40003">
        <property type="protein sequence ID" value="EEZ40003"/>
        <property type="gene ID" value="VDA_001023"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4775">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000184">
        <property type="entry name" value="Bac_surfAg_D15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039910">
        <property type="entry name" value="D15-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12815">
        <property type="entry name" value="PTHR12815"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01103">
        <property type="entry name" value="Omp85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1134">Transmembrane beta strand</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019379" evidence="4">
        <location>
            <begin position="21"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="Omp85" evidence="5">
        <location>
            <begin position="100"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="375" mass="42988" checksum="ED3E1BDC90612BB0" modified="2010-01-19" version="1">MLKKLLLSSLIMVNSPYLYATENEPQQDWIDNFLTQLGSSDTIDVSQGIDWGVLPGPFANPEQGVGFGIAAVGLYAPSDWVETTPYSTLAIKSYISSTGSYGLGLENRTYLNHDRLRLLGDVWISHSPQYYWGIGKKAAEDDRNKSEYQGRIFKVAPKISYQFLPHTYVTLGWDFQSYAKQKIDSNLLTAYQLEDQRSSGISTAFEYDSRDFEPNPYHGMLLFAEWVNFRKSLGSDQNYQRLTINYRQYVEISDSDVLAWDLHGQKVDGDIPWYGYAEMGNDDRMRGYYTGQYRDRYQLSSQIELRHRFNYRHGMVAWIGGGNIAPKSSELFSDSWLPSAGIGYRFTFKPRINVRIDYAVGKDSSGFYFNINEAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3M4</accession>
    <name>D0Z3M4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001025</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001025"/>
    <dbReference type="EnsemblBacteria" id="EEZ40005">
        <property type="protein sequence ID" value="EEZ40005"/>
        <property type="gene ID" value="VDA_001025"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021700">
        <property type="entry name" value="DUF3283"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11686">
        <property type="entry name" value="DUF3283"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="52" mass="5937" checksum="D3B9BFFDE04DC647" modified="2010-01-19" version="1">MDKQAAYAVWKVSNAKAGPEVFSELLNNIVDDDEREFFEQAVVKYKAQMGVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3V7</accession>
    <name>D0Z3V7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Response regulator VieA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001110</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306248.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001110"/>
    <dbReference type="EnsemblBacteria" id="EEZ40088">
        <property type="protein sequence ID" value="EEZ40088"/>
        <property type="gene ID" value="VDA_001110"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2200">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="3"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="3">
        <location>
            <begin position="135"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="390" mass="44158" checksum="1671F47DAB2D81E5" modified="2010-01-19" version="1">MKNILIIENNHFQANMLKHMLERIGFESIYSSDSIQTGLSICQSQAIDIILCDIELTSIDSVSFLNKLVAIGFEGQINFISALDSKISSTIQRMNDFLSVFIGEFIQKPITEKKIINAIFAPGPHQSHIEKKEPISISQRDIANGIKNHELINFYQPIYETRSQKLYGVEVLVRWQHPEYGLLSPYYFIEEAETSLLISDIFYLTAFNAIQDLSSIPEIGKISINVSQKTLSEEPICDWLIATCKQFNLPHHKVCIELTEGIVFVENQTVLENISRLRLNGFGLSIDDFGTGYSSLSKLASLPFTELKLDKSFIDQIEINESIESIIQHTIQLAHSLDLNVVAEGVETQRTFGKLREFNVDFCQGYLLGKPMALEQLYLHLSNELTQSVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z421</accession>
    <name>D0Z421_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hydrogenase 4 subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000277</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303922.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000277"/>
    <dbReference type="EnsemblBacteria" id="EEZ39259">
        <property type="protein sequence ID" value="EEZ39259"/>
        <property type="gene ID" value="VDA_000277"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3261">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3262">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="473681at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.645.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001135">
        <property type="entry name" value="NADH_Q_OxRdtase_suD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037232">
        <property type="entry name" value="NADH_quin_OxRdtase_su_C/D-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001268">
        <property type="entry name" value="NADH_UbQ_OxRdtase_30kDa_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014029">
        <property type="entry name" value="NADH_UbQ_OxRdtase_49kDa_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001501">
        <property type="entry name" value="Ni-dep_hyd_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029014">
        <property type="entry name" value="NiFe-Hase_large"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00329">
        <property type="entry name" value="Complex1_30kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00346">
        <property type="entry name" value="Complex1_49kDa"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00374">
        <property type="entry name" value="NiFeSe_Hases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143243">
        <property type="entry name" value="SSF143243"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56762">
        <property type="entry name" value="SSF56762"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00535">
        <property type="entry name" value="COMPLEX1_49K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Complex1_30kDa" evidence="1">
        <location>
            <begin position="45"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="Complex1_49kDa" evidence="2">
        <location>
            <begin position="304"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="domain" description="Complex1_49kDa" evidence="2">
        <location>
            <begin position="469"/>
            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="581" mass="66228" checksum="20BD80E2F54C9F23" modified="2010-01-19" version="1">MTSSIFETAINPQRIGKNYVDGVNHFFPSAIIDEEWQTENQVTITVKMTALVDVMKWLYYDQGGWLTVTFGNDERSLNGHFAVYHALSMEGEVKSWVTVKVLVDPVSQEFISITPTIPAAVWGEREVRDMYGLHPVGLPDERRLVLPDDWPEDLHPLRKDAMDYRQRPQPTTETETYQFDNQLGNDSNRIVPVGPLHITSDEPGHFRLFVDGEDIVDADYRMFYVHRGMEKLAETRMGYHEVAQLTDRVCGICGFTHSVGYSNTIENALDVDVPFRAKMIRTVLLEVERLHSHLLNIGLSSHFVGFDSGFMQFFRIREKTMELAELLTGARKTYGMNLIGGVRRDFLKEQRTKGIAMVREVRQSFSELVEMLLATPNIDSRICGVGILSKEIARNYSPVGPLIRGTGFKRDVRVIHGQQFEAYSKVPIELQTMENGDVQSRVMVRIREVFDALNIVEFGLDNLPAGAILTEGFNYVPNKFALGFTEAPRGENVHWSMTGDNQKLFRWRCRAATYANWPTLRYMLRGNTVADAPLIIGSLDPCYSCTDRVTIVDTKKKRSQTVPYKAIEQYSINRKNSPFKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-06-02" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z429</accession>
    <name>D0Z429_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000285</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39267">
        <property type="protein sequence ID" value="EEZ39267"/>
        <property type="gene ID" value="VDA_000285"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031MN3">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1264320at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="286" mass="32611" checksum="9A40323E70F8EB78" modified="2010-01-19" version="1">MNWRLMSIGFCSLLLMGCNDDNDNLFTTSNAPEQNTPTEETPSAEFPPSSNTEPELFIEPECDLENINLLDFEQWQREDGWWVGEYTLLGADGNPQVSNSWPYQYDHYMGFIHLEVIGNSIKQRNVFLYPPKNVDECDSDNQVIGNGVCGINGNEKIFSADQSASDCDGNLTGPYIAFGMTMDTHTTLIGDDTVLYQVRMSDGSLMQNQLTSLPPNDTRVRTAQGFFMNTPTYASYYRERKVTKEEFFELITQYRQEYQILETDHCAYDSGNQPSQTTCDEHFELE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z437</accession>
    <name>D0Z437_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Arylesterase</fullName>
            <ecNumber evidence="2">3.1.1.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000293</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.1.2" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303964.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000293"/>
    <dbReference type="EnsemblBacteria" id="EEZ39275">
        <property type="protein sequence ID" value="EEZ39275"/>
        <property type="gene ID" value="VDA_000293"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2755">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1247435at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004064">
        <property type="term" value="F:arylesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016298">
        <property type="term" value="F:lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008265">
        <property type="entry name" value="Lipase_GDSL_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01098">
        <property type="entry name" value="LIPASE_GDSL_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SGNH_hydro" evidence="1">
        <location>
            <begin position="24"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="200" mass="22638" checksum="FD1E2D9DBCE4A5AD" modified="2010-01-19" version="1">MIRILSLLFLLVSSTLSYSQTLLVLGDSLSAGYQMKPEQSWPALLPSILEQQQQPTTVINASISGDTSGNGLTRLPALLQQYQPNWVLIELGANDGLRGFAPSILKTNLSQMIEKIQQHDAKPLLMQIEIPPNYGKRYNQMFRQIYPDLSQKHQIPLLPFFLVEIIEQDNLMMKDRLHPTANAQPIIAKFMAKHLQPHLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4D7</accession>
    <name>D0Z4D7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MutT/nudix family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000393</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304240.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000393"/>
    <dbReference type="EnsemblBacteria" id="EEZ39375">
        <property type="protein sequence ID" value="EEZ39375"/>
        <property type="gene ID" value="VDA_000393"/>
    </dbReference>
    <dbReference type="GeneID" id="57343225"/>
    <dbReference type="eggNOG" id="COG0494">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1308416at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="2">
        <location>
            <begin position="20"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="179" mass="20590" checksum="34241AB6E47CEA0E" modified="2010-01-19" version="1">MRLLRSTTHPDLTDLSGSMFHRLAARAIILDGEDILLLYTERYHDYSLPGGGVDAGEDIVAGMIRELEEETGAQNIRNIKEFGLYEEYRPWYKPDFDIVHMESYCFTCEIDRQLGQTRLEDYEVKNGMRPVWINIFDAIAHNEKTIQESDKKGLSIERETFLLKQVVAECLTANLQQAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4Q1</accession>
    <name>D0Z4Q1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribose operon repressor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_000509</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304572.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000509"/>
    <dbReference type="EnsemblBacteria" id="EEZ39489">
        <property type="protein sequence ID" value="EEZ39489"/>
        <property type="gene ID" value="VDA_000509"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1796334at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00036">
        <property type="entry name" value="HTHLACI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="2"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="334" mass="37364" checksum="43DA600B3F5FEC0C" modified="2010-01-19" version="1">MATIKDVAKYAGVSTSTVSHVLNKTRFVSEEISQRVMNAVEVLNYAPSALARSLKVNQTSTIGMLVTTSTNPFFGEVVKGVERRCYQKGYNLILCNTEGDTERMHSNVDMLLQKRVDGLLIMCSEVEPNDYDLFGRHKPIPTVIMDWGPTNFPSDKIQDNSHHGGYLATQHLIDQGHTEIGCITGPLDKMTAQQRLSGFVQAMEENHLSIKKEWIIEGNFECDGGEEAFDKLIVQKSIPSALFICNDMMAMGAISSAFKHKIQIPNDMSIIGYDDIKLAQYMTPSLTTIHQPKYRLGQQAIDLLLDNIINKRVDNKIIQLEPTLVIRNSTVKNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4R4</accession>
    <name>D0Z4R4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Cytochrome c-type protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">VDA_000522</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="8">Binds 5 heme groups per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the TorC/TorY family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304609.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000522"/>
    <dbReference type="EnsemblBacteria" id="EEZ39502">
        <property type="protein sequence ID" value="EEZ39502"/>
        <property type="gene ID" value="VDA_000522"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3005">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="738283at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009276">
        <property type="term" value="C:Gram-negative-bacterium-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3820.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009154">
        <property type="entry name" value="Membr-bd_4haem_cyt_TorC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036280">
        <property type="entry name" value="Multihaem_cyt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005126">
        <property type="entry name" value="NapC/NirT_cyt_c_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038266">
        <property type="entry name" value="NapC/NirT_cytc_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03264">
        <property type="entry name" value="Cytochrom_NNT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000014">
        <property type="entry name" value="4_hem_cytch_TorC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48695">
        <property type="entry name" value="SSF48695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="7 8" id="KW-0349">Heme</keyword>
    <keyword evidence="7 9" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Cytochrom_NNT" evidence="10">
        <location>
            <begin position="4"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="binding site" description="covalent" evidence="8">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="8">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="8">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="8">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="8">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="8">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>3</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="8">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>4</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="8">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>4</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>4</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="8">
        <location>
            <position position="312"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>5</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="8">
        <location>
            <position position="315"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>5</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="316"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>5</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR000014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000014-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000014-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ39502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="364" mass="40614" checksum="40166778974DAE69" modified="2010-01-19" version="1">MKIKKTTVAVLVAAGIGIGWLTLGGTHYVLEKTSSTEFCLSCHTMETPYKEYQGSVHFSNSKGIQAQCADCHIPTDTKDYLLTKLRATKDIYHEFITGKIDTPEKYEEHRAELAETVWAQMRANDSATCRSCHNEEAMETYEQSEEAQKMHKYGIENDQTCIDCHKGVAHLLPETKMDSSALNHLLEQAKQTRSGAEFVYPIQTIAMGDLGSINPATPLKVLKDDQNKRTIELSGYQMQGAEQVLYMGQGQRAIIATLSDSGEKELKTGKFVTDSYGNNWRTASLTTKIDSPVLDSQKPLWSYAEQLDNVYCSTCHAKIPANHFTVNAWPSVAKSMGDRTSISAEDLEILTKYFQYNAKDVVGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4S3</accession>
    <name>D0Z4S3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Hydroxymethylpyrimidine ABC transporter ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_000531</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304642.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000531"/>
    <dbReference type="EnsemblBacteria" id="EEZ39511">
        <property type="protein sequence ID" value="EEZ39511"/>
        <property type="gene ID" value="VDA_000531"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1116">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1200451at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="5"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="37"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="255" mass="28664" checksum="7A98026B0EE43CF5" modified="2010-01-19" version="1">MAILLTCHSLTYPNASTATLSNVSLQLQAKQWTCLLGKSGSGKSTLLRLLASLLPDDVQFIGNIQTEHDENIHQHIAYMAQQDLLLPWLNVIDNVCLSYQFGSQKCQSEYKSCNAKKSVYQQAMTLLNKVGLRHYAEHMPQQLSGGMKQRVALARTLMQDKPIVLMDEPFSALDAVTRYKLQNLAVELLREKTVVLITHDPQEALRLGEQIIMLTGTPASLRQLNIPNSPIPRQLDSEFAQYQQEILSNLEAEYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4U6</accession>
    <name>D0Z4U6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chromosome (Plasmid) partitioning protein ParA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000179</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306527.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000179"/>
    <dbReference type="EnsemblBacteria" id="EEZ39163">
        <property type="protein sequence ID" value="EEZ39163"/>
        <property type="gene ID" value="VDA_000179"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1192">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="729012at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025669">
        <property type="entry name" value="AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13614">
        <property type="entry name" value="AAA_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_31" evidence="1">
        <location>
            <begin position="101"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="388" mass="44360" checksum="929E40C437EAD216" modified="2010-01-19" version="1">MSKTKVEIDKLKERADLYIKKRNDFYPKEERLYTRQEASDYLAINKVTLDNYVKSLGFNVKDREGMLWSMSISELYDFESQLPDNLKKHEHFKRKPNQKCHVLMFQNQKGGVGKTVSAATVASCLSAEFPEKLRIGLIDLDGQSTLSMYYAANAQRDGEFSVGDIVRGNYELDEGETFEGLVKGAFLKTTIPNLRILPALQSDRSLEGWFHRVHSELDNPYGLVKSIVDAVEDEFDIIILDTPPSLSFMTYNGYFAATSIIFPLAANENDIDATCNYFANLPEVWALLEQYDHPGYDFIRLMVTNYRQTISNTSLMNQLNRSFGEWLYPTQFKHSEAVQLCTSMMNTVFDLAASEYPKTKKTLNDARTNAFEVASQIYRDIDNVWGAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4Y1</accession>
    <name>D0Z4Y1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ADPrib_exo_Tox domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000214</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39198">
        <property type="protein sequence ID" value="EEZ39198"/>
        <property type="gene ID" value="VDA_000214"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5033PMU">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090729">
        <property type="term" value="F:toxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003540">
        <property type="entry name" value="ADP-ribosyltransferase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03496">
        <property type="entry name" value="ADPrib_exo_Tox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0800">Toxin</keyword>
    <feature type="domain" description="ADPrib_exo_Tox" evidence="2">
        <location>
            <begin position="380"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="575" mass="63250" checksum="5448DF1EE8C5FB55" modified="2010-01-19" version="1">MIQPRDHSFTEIMGALDAYAMEHNDHGAATVDSDDMMTWQARETGNWLGAYEGLITQDIDLPGMEAKTITLNGQEIHLPAIEPVKMSVEEFDHSVTQGKGYPSQYAGSKYLDVLAQAAQSHQEADDAFGLASEKIHYAAQNMNDLKLYNTEQRTMPELPERKPSGQPFIDGAKAEALGNWLERQSPAQYQQLLSNAASLLAESSQEGSLSNVFRYGERNDVWETFRTVDKSNMLDAQLVLKNKPEHQDALGFLLDVASSKATPAERQQAVLEAIGDDANNQATLINAMLLATTRFYTGNGANIINPGYGDFAPPKNESEMEMRLQSLQKRNQYTSYAERAQAKKEYRQNVDTLQAAIDSPMFERYSGKVWHGCHTSVADVALEKGSGFQFPGFMSTTRAPDVAQSYMAKGALFVINPAPAIGVNIEPISNAEGEREILVPAGTSFTVEQSYTLHLEKGYPPSANTVMKKRIHDTEVAMGSRIPHVTIRITTPEMEKVGLSGQSDPKGEAELADLIDHIKKNSSNMEEQTKVVVLSRESSAPSANTVNADKAATEVFNLNRFSLLETETVKLSTPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z516</accession>
    <name>D0Z516_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000249</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306730.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39233">
        <property type="protein sequence ID" value="EEZ39233"/>
        <property type="gene ID" value="VDA_000249"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="64" mass="7276" checksum="478D83BFD40A8634" modified="2010-01-19" version="1">MDNVIQLLNTQYDIAPPKDHNEEIALIYQYLIDKFGDTSTTAFKLHEVLISLAHIAERDGATPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z570</accession>
    <name>D0Z570_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000120</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306906.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000004.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39104">
        <property type="protein sequence ID" value="EEZ39104"/>
        <property type="gene ID" value="VDA_000120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="179" mass="20975" checksum="7F4196A45A3E710C" modified="2010-01-19" version="1">MQRQIQLGDTVHETIQISVTRKTKNDLIWYGVINQVLIARGYKQTRNTRWEGEFIFDREERFSIRTPAERALKEAIKVAGKRSVTISLVLGKFPKYQLSTRDIFAKYDIKHFSYLKRLTQSISIHTPPKNKPRPKPKKLDVYEVACLYRDGLEVAVIAKKLRTTQAQIYMILNNDIFNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z599</accession>
    <name>D0Z599_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000149</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306987.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000004.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39133">
        <property type="protein sequence ID" value="EEZ39133"/>
        <property type="gene ID" value="VDA_000149"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031NTC">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2103716at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="170" mass="19211" checksum="FFA468E319271713" modified="2010-01-19" version="1">MSKNEIVTLAIAAIALGFSIWQGNSQIEHNHVSVEPRVTSYFSNHGPEGKWGIYIINNGMGTAFVKSLDIKVNGKSVSDHEFGKFYQAVVDLDLNPMCFIMGAPRPNDSFQVGEEVSLIESNEKAKQSCARDYLLLREYQKNKLDYELVIESIYGDTFTYKYSKNQQVKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVH8</accession>
    <name>D0YVH8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Deoxyguanosinetriphosphate triphosphohydrolase-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001558</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the dGTPase family. Type 2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298275.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001558"/>
    <dbReference type="EnsemblBacteria" id="EEZ40532">
        <property type="protein sequence ID" value="EEZ40532"/>
        <property type="gene ID" value="VDA_001558"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0232">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="370035at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008832">
        <property type="term" value="F:dGTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006203">
        <property type="term" value="P:dGTP catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01212">
        <property type="entry name" value="dGTPase_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006261">
        <property type="entry name" value="dNTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020779">
        <property type="entry name" value="dNTPase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023023">
        <property type="entry name" value="dNTPase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026875">
        <property type="entry name" value="PHydrolase_assoc_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11373:SF32">
        <property type="entry name" value="PTHR11373:SF32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13286">
        <property type="entry name" value="HD_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01353">
        <property type="entry name" value="dGTP_triPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD" evidence="2">
        <location>
            <begin position="64"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="442" mass="50815" checksum="2FEA400799C31BCA" modified="2010-01-19" version="1">MTSEFDLSELWQERYSNEQKMRRNDHRSAFQRDRARILHSAAFRRLQAKTQVHSTGLDDFYRTRLTHSLEVSQIGTGIVAQLKLKQPNFRALLPSTSLMESLCLAHDIGHPPFGHGGEVALNYMMHKHGGFEGNAQTFRIVTHLEPYTENLGMNLARRTLLGLIKYPALLSQTQPLVFPAEVPNFRRMKASEWHPAKGIYDDDKTTFDWVLALLSDNDRSLFNQMRCSRIDDVTPLKTRFKSLDCSIMELADDIAYGVHDLEDAIVMGIVTREQWQEAVASKLAECGDPWIEEQISKISDQMFGSHHERKDAIGALVNALLTSINIAPSIQDGIHRFDEPLLQWNAYLSETMELVLNTLKQFVSIYVVKKPEIQLFEYKGQQLVMELFEVFASDPERLLPEETRQRWLEAYTNESNPMRVIADYISGMTDGYTQRLYERLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVN3</accession>
    <name>D0YVN3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Putative methyl-accepting chemotaxis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">VDA_001198</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the methyl-accepting chemotaxis (MCP) protein family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297620.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001198"/>
    <dbReference type="EnsemblBacteria" id="EEZ40176">
        <property type="protein sequence ID" value="EEZ40176"/>
        <property type="gene ID" value="VDA_001198"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0840">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="477199at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033479">
        <property type="entry name" value="dCache_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02743">
        <property type="entry name" value="dCache_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0807">Transducer</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="288"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="12">
        <location>
            <begin position="308"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="10">
        <location>
            <begin position="367"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="11">
        <location>
            <begin position="554"/>
            <end position="616"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ40176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="639" mass="69777" checksum="2CC9854E4F452B44" modified="2010-01-19" version="1">MNLNHLSIKKKLILAMISAVLFSTALVGILSQQQARKVIETRLLESEIPATLLQIRNQIDKEVSLLQAAAQQLATNPLVIDSLTATLPQDNTQLVTLLNEIKQQYHLFDASIADRNTGNYWNQDGFLRQLNHQQDSWFYNFVRSGNAKMLNVFREANGDVKLFVNYQQLNGKGLAGLSKSLDEMVQFINQFKLEQTGFVYLVDDKGIVRIHNDNQLMGKASLTDLYGSKVANQLLKRGKIEIVDLDLDLAGQENLVASSYIPTMNWYVIAQLPKNEAFASLNHARNQILIWTAIIALGFTALAIWLASSITRPIARLAEMFKDLGEGEGDLRHRLDIQGNDEIAQLSQGFNGFISKIHNSVKEVAETGNALRHASQSVAEQAQTTLDNSQSQRDRTIQVVTAINEMGATVNEIAGNAAQAADATHLAETEAQSGQQVVGQARETISQLSHDVAQVSEVIESLAHNTQAIGSILDVIRGISEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLASRTAASTDEIQTMINRLQQEASNAVAAIEQSRLLSSNGVSASDEASSALISIAERITLIADMNTQVATATEEQSTVVNDINCNIEVINETTQRTATTAEDLAQASLELQQLSHRLEVMVGSFKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVN8</accession>
    <name>D0YVN8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001203</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0231 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001203"/>
    <dbReference type="EnsemblBacteria" id="EEZ40181">
        <property type="protein sequence ID" value="EEZ40181"/>
        <property type="gene ID" value="VDA_001203"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3112">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008249">
        <property type="entry name" value="UPF0231"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06062">
        <property type="entry name" value="UPF0231"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="49" mass="5872" checksum="F1BF1BC83AE45824" modified="2010-01-19" version="1">MVQANYLFSEDDTELEEDMNFYDEENISVCGFEDLEQVLLAWQAFVKRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVZ5</accession>
    <name>D0YVZ5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase</fullName>
            <ecNumber evidence="7">2.7.7.60</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">4-diphosphocytidyl-2C-methyl-D-erythritol synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">MEP cytidylyltransferase</fullName>
            <shortName evidence="7">MCT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ispD</name>
        <name evidence="8" type="ORF">VDA_001274</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>2-C-methyl-D-erythritol 4-phosphate + CTP + H(+) = 4-CDP-2-C-methyl-D-erythritol + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:13429"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:57823"/>
            <dbReference type="ChEBI" id="CHEBI:58262"/>
            <dbReference type="EC" id="2.7.7.60"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 2/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.60" evidence="7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001274"/>
    <dbReference type="EnsemblBacteria" id="EEZ40252">
        <property type="protein sequence ID" value="EEZ40252"/>
        <property type="gene ID" value="VDA_001274"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1211">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00093"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050518">
        <property type="term" value="F:2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02516">
        <property type="entry name" value="CDP-ME_synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00108">
        <property type="entry name" value="IspD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001228">
        <property type="entry name" value="IspD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034683">
        <property type="entry name" value="IspD/TarI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018294">
        <property type="entry name" value="ISPD_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01128">
        <property type="entry name" value="IspD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00453">
        <property type="entry name" value="ispD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01295">
        <property type="entry name" value="ISPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="5 7 8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7 8" id="KW-0808">Transferase</keyword>
    <feature type="site" description="Transition state stabilizer" evidence="7">
        <location>
            <position position="7"/>
        </location>
    </feature>
    <feature type="site" description="Positions MEP for the nucleophilic attack" evidence="7">
        <location>
            <position position="140"/>
        </location>
    </feature>
    <feature type="site" description="Positions MEP for the nucleophilic attack" evidence="7">
        <location>
            <position position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ40252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="218" mass="23417" checksum="59EEB54BE722F370" modified="2010-01-19" version="1">MAADRPKQYLEIAGKTILEHTVDRLFSHPSIGRIVIAISAGDPYFPTLPLASDPRITVVDGGAERADSVFSGLAVVDDNDWVLVHDAARPCVRTSDLSQLIDAALLSESGAILAAPVRDTMKRGAASDSEHGTICSTVDRNNLWHALTPQMFKAAQLKAALTYALEQGATITDEASALEFCGYAPLLVKGRADNLKVTQPEDLALAGFYLEQLMKELP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWF0</accession>
    <name>D0YWF0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001398</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001398"/>
    <dbReference type="EnsemblBacteria" id="EEZ40373">
        <property type="protein sequence ID" value="EEZ40373"/>
        <property type="gene ID" value="VDA_001398"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020010">
        <property type="entry name" value="CHP03503"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03503">
        <property type="entry name" value="TIGR03503"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018687" evidence="2">
        <location>
            <begin position="21"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="372"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="411" mass="47015" checksum="3784707B806AE317" modified="2010-01-19" version="1">MSVLKRLLLLLIWISPFSWAQDSTSMSLLDNRFRIDQDVQSVSFIIHRQKSSEAAILVRPDGQKYYAWRHPNNVTWYQQPDLDIVSIEKPMAGPWQALGKISPHNSITVLSDVHLSAQQLPQRLYQGETLKFSAQLWQGNEPLQLAAYLSHVKLKISFTDLTSKPKDGQILPAIVLAEFFDDGQKRDERVGDGIFTANLNVDIPPGRYQATIATENGVFLRQLEQTVLVYPTPLTYSFMAGETVKDNSEFVAKVTDDQLQAGSLAGHIAVKGPSGKEYIVQGTTQDEEKQLNLTFPAMDKVGRYRWYGWLYATDNFNQRELIFSLPKRSFALAAQMQLTKDLQQLKQEELVKQQQEKIKQQQLAEAKQRDDALLWLIVGNSVMVLVILIGWYGLRWWKKKRQHKLDDLMLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWH3</accession>
    <name>D0YWH3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ysc84 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001432</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298052.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001432"/>
    <dbReference type="EnsemblBacteria" id="EEZ40406">
        <property type="protein sequence ID" value="EEZ40406"/>
        <property type="gene ID" value="VDA_001432"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2930">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1808930at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007461">
        <property type="entry name" value="Ysc84_actin-binding"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04366">
        <property type="entry name" value="Ysc84"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018688" description="Ysc84 domain-containing protein" evidence="1">
        <location>
            <begin position="26"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="Ysc84" evidence="2">
        <location>
            <begin position="90"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="231" mass="24433" checksum="BE22DC7FB039471D" modified="2010-01-19" version="1">MKPVYRLFSMLCAAALLCISSLSHASSDPDTEAALNKFKQAPQTWPFFHSSYGYAIFPSVGKGGFWIGGAYGSGTAYRGNTITGYAKLYQVSIGLQFGGQAYSEIIFFQDKRAYDRFTSGSFELEAQASAVAITEGAQAKAGTTGVNASAGNDYVNASYVNGVAIFTLAKGGLMLEAAIAGQKFDYEPISDITRKVKGLDAPSPAKAAKPTAPVEKKSEAAVIVDTVEELQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWK5</accession>
    <name>D0YWK5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">TagF domain protein</fullName>
            <ecNumber evidence="7">2.7.8.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_001496</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CDP-glycerol glycerophosphotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.12" evidence="7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298159.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001496"/>
    <dbReference type="EnsemblBacteria" id="EEZ40470">
        <property type="protein sequence ID" value="EEZ40470"/>
        <property type="gene ID" value="VDA_001496"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1216">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1887">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1162846at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047355">
        <property type="term" value="F:CDP-glycerol glycerophosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019350">
        <property type="term" value="P:teichoic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007554">
        <property type="entry name" value="Glycerophosphate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043148">
        <property type="entry name" value="TagF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043149">
        <property type="entry name" value="TagF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04464">
        <property type="entry name" value="Glyphos_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0777">Teichoic acid biosynthesis</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="6">
        <location>
            <begin position="4"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="688" mass="79774" checksum="02478D99E3BCFDD1" modified="2010-01-19" version="1">MKISIIITLYNRANIVDKAIESALKQDYNNKEIIIVNDGSTDNYEDALAPYKDQVIIYTQENKGCAGAKNKGVELATGEYIIFLDSDDTFYSDSVLTDCYKEIATGSQFVGYSQAEMIRSGVGPSIEKANFSSSINIQKHMLESPLNYAAFPPMCLNKRIYQQVGGMQEKIRWGDAINFWRYYFSHVDKISYIHKPGYSYNLTGDDNMSKASDKSVKEKFKMMTDVIDEAFNNHKSKMSPSEQSTWLLILYLYSLKSNNKTQRKNYFSQLKTKSLFNISKSFLYLLNSKMIPKLINKLSAITLKIKKKNIFNGCISSLLVKRDQLDPNTIIINSTINKNFNFNSKYFFEYLENEQHGFNVYFIVNNDKTRNELNKKYPGKFITNYLSHDIKIISKAKTWLCSTLDLPVYFCFKHPDRIVYHFGHGVPLKNIGLNEPKISIPRYINRYKNIRCFTHVTCYSREFQNKMEKMFGGLKAEYLPLGQPRNDSISQSSSHKPISSFFDHDLDIEKYVLYSPTWRYDSTTKFFPFSDFDVQKLHQYLDESNTVLILREHPFYPAIMPDGLCDHSRVKNLSSKVISDFTPYILDMDTIITDYSSLYLDGLSNPKTNFIFIPYDIENYTKLTGFSMPYEELTPGPKALSFEAFIQALENNDDQNYGIQKRELAELFNVKYSGNCHEHFEYIKNLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWL7</accession>
    <name>D0YWL7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Putative capsular polysaccharide transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">VDA_001508</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell outer membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the BexD/CtrA/VexA family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001508"/>
    <dbReference type="EnsemblBacteria" id="EEZ40482">
        <property type="protein sequence ID" value="EEZ40482"/>
        <property type="gene ID" value="VDA_001508"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046930">
        <property type="term" value="C:pore complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015159">
        <property type="term" value="F:polysaccharide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015288">
        <property type="term" value="F:porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003715">
        <property type="entry name" value="Poly_export"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019554">
        <property type="entry name" value="Soluble_ligand-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040716">
        <property type="entry name" value="Wza_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02563">
        <property type="entry name" value="Poly_export"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10531">
        <property type="entry name" value="SLBB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18412">
        <property type="entry name" value="Wza_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="13" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0564">Palmitate</keyword>
    <keyword evidence="8" id="KW-0625">Polysaccharide transport</keyword>
    <keyword evidence="10" id="KW-0626">Porin</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SLBB" evidence="14">
        <location>
            <begin position="114"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="SLBB" evidence="14">
        <location>
            <begin position="197"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="Wza_C" evidence="15">
        <location>
            <begin position="291"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF10531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF18412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EEZ40482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="326" mass="35879" checksum="0D3E250D32F75DEE" modified="2010-01-19" version="1">MAKFRQKKVNAQNNPALDAKIAGYEYRIGPGDILNITIWDHPELTIPAGSYRSASEAGNWVQADGTIFYPYIGSVKVVGKTVMEVRSEIARRLAAYIESPQVDVNVAAFRSQKAYVTGEVKNPGQQPISNIPLTLLDAVNKAGGLAEDADWRHVTITRDGKDQTVSLYALMQRGDLTQNRLMQDGDIIHVPRNDAQKVFVMGEVNKPQLLKIDRAGMSLTEALSSVGGINELEADATGVFVIRANRDSKGNMNQDESIANIYQLNIKDAAALVIGTEFELEPYDVVYVTAAPIAKWNRVVRQLMPTISGFNELTEGVNRFTDLRAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWN5</accession>
    <name>D0YWN5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 16">Phospholipase A1</fullName>
            <ecNumber evidence="6 16">3.1.1.32</ecNumber>
            <ecNumber evidence="7 16">3.1.1.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Phosphatidylcholine 1-acylhydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">VDA_001491</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 16">
            <text>a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1-acyl-sn-glycero-3-phosphocholine + a fatty acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15801"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
            <dbReference type="ChEBI" id="CHEBI:57643"/>
            <dbReference type="ChEBI" id="CHEBI:58168"/>
            <dbReference type="EC" id="3.1.1.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 16">
            <text>a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 2-acyl-sn-glycero-3-phosphocholine + a fatty acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18689"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
            <dbReference type="ChEBI" id="CHEBI:57643"/>
            <dbReference type="ChEBI" id="CHEBI:57875"/>
            <dbReference type="EC" id="3.1.1.32"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="16">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="16">Binds 1 Ca(2+) ion per monomer. In the dimeric form the Ca(2+) is bound by different amino acids with binding of each Ca(2+) shared with ligands coming from each monomer. The Ca(2+) ion may have a role in catalysis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 16">Homodimer; dimerization is reversible, and the dimeric form is the active one.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="16">Cell outer membrane</location>
            <topology evidence="16">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <text evidence="16">One of the very few enzymes located there.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 16">Belongs to the phospholipase A1 family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.32" evidence="6 16"/>
    <dbReference type="EC" id="3.1.1.4" evidence="7 16"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298151.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001491"/>
    <dbReference type="EnsemblBacteria" id="EEZ40465">
        <property type="protein sequence ID" value="EEZ40465"/>
        <property type="gene ID" value="VDA_001491"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2829">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1546598at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052740">
        <property type="term" value="F:1-acyl-2-lysophosphatidylserine acylhydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052739">
        <property type="term" value="F:phosphatidylserine 1-acylhydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008970">
        <property type="term" value="F:phospholipase A1 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004623">
        <property type="term" value="F:phospholipase A2 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003187">
        <property type="entry name" value="PLipase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036541">
        <property type="entry name" value="PLipase_A1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40457">
        <property type="entry name" value="PTHR40457"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02253">
        <property type="entry name" value="PLA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01486">
        <property type="entry name" value="PHPHLIPASEA1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56931">
        <property type="entry name" value="SSF56931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="16" id="KW-0106">Calcium</keyword>
    <keyword evidence="15 16" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="13 16 17" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="16" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="16" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="11 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12 16" id="KW-0732">Signal</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1134">Transmembrane beta strand</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019617946" description="Phospholipase A1" evidence="16">
        <location>
            <begin position="25"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00021726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU366027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EEZ40465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="284" mass="32568" checksum="DB303503166CFC0E" modified="2010-01-19" version="1">MNRNVLMTSGMLLAAVCYMSHAHADELASPVNNPLDYSSNNSLLLEQYKDNFILPVYYTSNPDKSEYSPEIPGGDHFSNTKVNFQISLKYKMFSNLLTDNDAMYVAYTQRSNWQAYVSSAYFQDNEYEPSLFWSFSAKLAETSDWQYAGTTFGFVHQSNGRGGNDERSWNRAFADVSFKNDQFTLSVKPWLRLDMGGRDYNSNIENYLGNGRISLNWMPTKEHSLTFTVRNALESGFSRSYEKLTWNFPIYKRLRGYMLVESGYGLSISDYDHYDNGVGMGIAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWS8</accession>
    <name>D0YWS8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphoglycerate transport regulatory protein PgtC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001473</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298124.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001473"/>
    <dbReference type="EnsemblBacteria" id="EEZ40447">
        <property type="protein sequence ID" value="EEZ40447"/>
        <property type="gene ID" value="VDA_001473"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1840">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1567509at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019779" evidence="1">
        <location>
            <begin position="20"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="413" mass="47335" checksum="9D071967A28F2C7E" modified="2010-01-19" version="1">MMRYLLLFILFCFAYTAKAQQLTILTTFTESTIAPLIWQFQQQHPDLEIDVLSRRESAALRQITQSRRHIDVIVSSSRIIFTPLIKNHELLPLPQSLQSKQGKYAFFQYPDPNIAIFGYSGYGFIANQDYLSSHQLPAPTSWEMLTDPMYAGHVAIGSPSRSITTHFMVESILQHYGWDKGWALLYQIAGNTKQIAARSYGVSDMVSQGTAGVGPVLDSFAFEYQKQFPFIEFHYQKNTPRLPSFIAGIKHSTPNKYTLEFINYVLSASTQRELKSLINKYAIDDKMTRPELPEPLRLSLMKQRDLLVKYLFDQTISYQLTSLNQAWRLLHNIEKYQKELTPAQQKVYLQAKQLASTPPISAQDAATKNFAYLSPSRQDTATQKTLTQWRDTMHNNLLESIAISQRLLSQLRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWW0</accession>
    <name>D0YWW0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 13">Aspartate-semialdehyde dehydrogenase</fullName>
            <shortName evidence="13">ASA dehydrogenase</shortName>
            <shortName evidence="13">ASADH</shortName>
            <ecNumber evidence="8 13">1.2.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Aspartate-beta-semialdehyde dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">asd</name>
        <name evidence="15" type="ORF">VDA_001533</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 13">Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>L-aspartate 4-semialdehyde + NADP(+) + phosphate = 4-phospho-L-aspartate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:24284"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57535"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="1.2.1.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4 13">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 2/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 13">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 2/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5 13">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 2/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7 13">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 13">Belongs to the aspartate-semialdehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.11" evidence="8 13"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298228.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001533"/>
    <dbReference type="EnsemblBacteria" id="EEZ40507">
        <property type="protein sequence ID" value="EEZ40507"/>
        <property type="gene ID" value="VDA_001533"/>
    </dbReference>
    <dbReference type="GeneID" id="57342410"/>
    <dbReference type="eggNOG" id="COG0136">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1799040at2"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00016"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00463"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00464"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004073">
        <property type="term" value="F:aspartate-semialdehyde dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071266">
        <property type="term" value="P:'de novo' L-methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019877">
        <property type="term" value="P:diaminopimelate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02121">
        <property type="entry name" value="ASADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000319">
        <property type="entry name" value="Asp-semialdehyde_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012080">
        <property type="entry name" value="Asp_semialdehyde_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005986">
        <property type="entry name" value="Asp_semialdehyde_DH_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000534">
        <property type="entry name" value="Semialdehyde_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012280">
        <property type="entry name" value="Semialdhyde_DH_dimer_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01118">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02774">
        <property type="entry name" value="Semialdhyde_dhC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00859">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01296">
        <property type="entry name" value="asd_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01103">
        <property type="entry name" value="ASD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 13" id="KW-0220">Diaminopimelate biosynthesis</keyword>
    <keyword evidence="11 13" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="12 13" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="13" id="KW-0521">NADP</keyword>
    <keyword evidence="13 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 13" id="KW-0791">Threonine biosynthesis</keyword>
    <feature type="domain" description="Semialdhyde_dh" evidence="14">
        <location>
            <begin position="6"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="13">
        <location>
            <position position="132"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="13">
        <location>
            <position position="245"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="13"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="41"/>
            <end position="42"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="162"/>
            <end position="163"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="316"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00010584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00013120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEZ40507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="337" mass="37268" checksum="07EE3526A2EE8147" modified="2010-01-19" version="1">MSQEFDIAILGATGAVGEAMVEVLEERQFPVRNLYLLASDRSAGKVLRFKGKSARVTDVEDFDWSQVQIALFSAGAEASERWAPIAADEGVIVIDNTSRFRYDYDVPLVIPEVNPEAIAEYRNRNIIANPNCSTIQMLVALKPIHDAYGIERINVATYQSVSGSGKKGVDELAGQTAKLLNGLPVETNAYPKQIAFNCLPHIDQFMDNGYTKEEMKMVWETQKIFCDPNIRVNPTCVRVPVFYGHAEAVHVETAQPVNIEEALQLLENAEGIELFHGAEYPTQVSDATGKDHVMVARVREDISHPCGLNMWVVADNVRKGAATNAVQIAEKLISDYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX65</accession>
    <name>D0YX65_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Putative transport protein VDA_001830</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_001830</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the AAE transporter (TC 2.A.81) family. YbjL subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298782.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001830"/>
    <dbReference type="EnsemblBacteria" id="EEZ40798">
        <property type="protein sequence ID" value="EEZ40798"/>
        <property type="gene ID" value="VDA_001830"/>
    </dbReference>
    <dbReference type="GeneID" id="57342054"/>
    <dbReference type="eggNOG" id="COG2985">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3273">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1458740at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1450">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01015">
        <property type="entry name" value="YbjL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006037">
        <property type="entry name" value="RCK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036721">
        <property type="entry name" value="RCK_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023017">
        <property type="entry name" value="Transp_YbjL_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006512">
        <property type="entry name" value="YidE_YbjL"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06826">
        <property type="entry name" value="Asp-Al_Ex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02080">
        <property type="entry name" value="TrkA_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116726">
        <property type="entry name" value="SSF116726"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01625">
        <property type="entry name" value="YidE_YbjL_dupl"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51202">
        <property type="entry name" value="RCK_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0407">Ion channel</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="61"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="92"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="163"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="383"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="409"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="450"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="474"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="506"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="537"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="6">
        <location>
            <begin position="206"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="6">
        <location>
            <begin position="293"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="560" mass="60495" checksum="61D75621912371FD" modified="2010-01-19" version="1">MNIDVAALLHQNNILLLFVVLAVGLAFAKVRIANMQLGNSIGVLLTALVFGNAGFTFNADALNIGFMLFIYCVGIEAGPNFFGIFFRDGKHYLLLALVVLLSAIGITMTMAHYLDMNLGLATGLMAGSLTATPVLVGAKDALNSGLSDITDPNMIKNLVESLSVGYAMSYLVGLVSLILLAKLMPKLQKQDLAESSQQIARERGIGEVSQRKVYLPIIRAYRVGPELINWIDGRNLRELGIYRQTGCYIERVRRNGILANPDGDAILQEGDEIALVGYPDSHARLDPSFRNGKEVFDRDLLDLRIVEEEIVVKNDSIAGKRLSELNLSEYGCFLNRVVRAQIEMPMDHNILLNKGDILQVSGEKSRVHGLAERIGFISVHSQIADLLAFCCFFILGLLLGLITMTFGHVAFGLGSAAGLLVAGITLGFLRANHPTFGYVPQGALNMTKDLGLMVFMVGIGLSAGSNLFESITQIGPTVFVTSLMVSVIPVVLAYLFGAYVLRMNRALLFGAIIGARTCAPAMDMINEHARSTIPALGYAGTYAIANVLLTIAGTLIIILK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX87</accession>
    <name>D0YX87_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001946</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001946"/>
    <dbReference type="EnsemblBacteria" id="EEZ40914">
        <property type="protein sequence ID" value="EEZ40914"/>
        <property type="gene ID" value="VDA_001946"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="19"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="310" mass="34455" checksum="BA4B132962366C04" modified="2010-01-19" version="1">MNLRHKSVETNKLIALMPDLAVFIIVVDEGSYTAAAKKLGVTPSALSKQVSKLEKALSVKLLERTTRKLVMSESGKRIYEQCTAMMSAAKQAVEISSSEHTIPAGTVTVAAPKAFMSIMLQPLVTPFLNLYPDIQLKIKARDGDIDLLAEEIDIVFRLTEKPIEGQVLKQVGKVNLVLCASPDYIARKGLPQHPLELKHHDCIYLGETNTDHIWEFHQGTERHSIAVTGRYAVNHSQMRLKGVQDGLGIGIFPDFVIKEALAEGSVIDVLPEWTIRGNYQGVIALQYAQTKYMPARVRVFIDYVTQHLPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXA9</accession>
    <name>D0YXA9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Translation initiation factor IF-1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">infA</name>
        <name evidence="5" type="ORF">VDA_001649</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the IF-1 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298441.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001649"/>
    <dbReference type="EnsemblBacteria" id="EEZ40622">
        <property type="protein sequence ID" value="EEZ40622"/>
        <property type="gene ID" value="VDA_001649"/>
    </dbReference>
    <dbReference type="GeneID" id="57342268"/>
    <dbReference type="eggNOG" id="COG0361">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2066663at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04451">
        <property type="entry name" value="S1_IF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00075">
        <property type="entry name" value="IF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006196">
        <property type="entry name" value="RNA-binding_domain_S1_IF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004368">
        <property type="entry name" value="TIF_IF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33370">
        <property type="entry name" value="PTHR33370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01176">
        <property type="entry name" value="eIF-1a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00008">
        <property type="entry name" value="infA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50832">
        <property type="entry name" value="S1_IF1_TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2 3" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="2 3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="S1-like" evidence="4">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="72" mass="8219" checksum="CDE1A4D345DC77C7" modified="2010-01-19" version="1">MAKEDVIEMQGTVLDTLPNTMFRVELENGHVVTAHISGKMRKNYIRILTGDKVTVELTPYDLTKGRIVFRAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXF7</accession>
    <name>D0YXF7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Oligopeptide transport ATP-binding protein OppF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_001636</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298418.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001636"/>
    <dbReference type="EnsemblBacteria" id="EEZ40609">
        <property type="protein sequence ID" value="EEZ40609"/>
        <property type="gene ID" value="VDA_001636"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4608">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1303270at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01727">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="16"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="54"/>
            <end position="61"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="328" mass="36159" checksum="D51AADC2F9A75C88" modified="2010-01-19" version="1">MLAEKKVLLDIDELKVHFSIAAKSSWPWSKPTQLKAVDGVSIRIFEGETLGVVGESGCGKSTFARAIIGLVEATEGKVVWLGQDLTALSAKELRLKRKEIQMIFQDPLASLNPRMTVGEIIAEPLKTFYPELSKDEVKQKVKEMMAKVGLLPNVINRYPHEFSGGQCQRIGIARALILKPKMIICDEPVSALDVSIQAQVVNLLKSLQQEMGLSLIFIAHDLSVVKHISDRVLVMYLGNAVEMGEGEALFADPKHPYTKALMSAVPIPDPELERNKHIELLEGDLPSPMNPPSGCVFRTRCPKATEECSRLKPKLQGSDYHAVACINV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXN1</accession>
    <name>D0YXN1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Anaerobic glycerol-3-phosphate dehydrogenase subunit C</fullName>
            <ecNumber evidence="5">1.1.5.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001772</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.5.3" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298671.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001772"/>
    <dbReference type="EnsemblBacteria" id="EEZ40740">
        <property type="protein sequence ID" value="EEZ40740"/>
        <property type="gene ID" value="VDA_001772"/>
    </dbReference>
    <dbReference type="GeneID" id="57342124"/>
    <dbReference type="eggNOG" id="COG0247">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1951488at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052591">
        <property type="term" value="F:sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009061">
        <property type="term" value="P:anaerobic respiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004017">
        <property type="entry name" value="Cys_rich_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017753">
        <property type="entry name" value="G3P_DH_GlpC_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02754">
        <property type="entry name" value="CCG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13183">
        <property type="entry name" value="Fer4_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03379">
        <property type="entry name" value="glycerol3P_GlpC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="47"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="403" mass="45236" checksum="BD73CD3D7E87E6CD" modified="2010-01-19" version="1">MSLLKDTSFDQCIKCTVCTVYCPVAKANPQYPGPKQCGPDGERLRIKSPDFYDETLKLCTNCKRCETACPSGVKIGDLIASARDQHAKMDLNIKTIRDFVLSHTDLMGTVATPFAPVINAVTGSKPVKTIMHKTIGVHDHKSLPKYSHGTFRGWYKKHGQEQQNFTRHVHYFHGCYVNYNNPDQGKDFVKVMNAMGLGVQLMGKEKCCGVPLIANGFFDKAKKNARLNVKNFEQAIEQYDSTIVSTSSTCAFTLREEYPHVLKVDNSKVANKIEYVTKFLLKEFMNGNMPKMKPINKKVVYHTPCHLERMGGTLYTIELLKMIPGLELQVLDSQCCGLAGTYGFKTENYDTSMKIGHDLFEQIKAADADFAITDCETCKWQIEENTQLETIHPISLLAMALAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXN6</accession>
    <name>D0YXN6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001735</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40703">
        <property type="protein sequence ID" value="EEZ40703"/>
        <property type="gene ID" value="VDA_001735"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG50333PG">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020240">
        <property type="entry name" value="UPF0412_YaaI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10807">
        <property type="entry name" value="DUF2541"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019870" evidence="1">
        <location>
            <begin position="23"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="153" mass="16518" checksum="C53D4170E9408395" modified="2010-01-19" version="1">MRKIFALTAAALLALVTLTGCQSTGGKNVGEGEWAKLAEKTVNFKSETDTVTPNPMFVNRSFSHVKLTCTQGTVDIKDITVNYTDGTSQKLDTLGILTKGSSTRAMKLNDDTKKVKNIEMQYSSLGSQTLNLAGVTKKAKVEVLGKRNVTTNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXP6</accession>
    <name>D0YXP6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="12">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">VDA_001749</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298621.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001749"/>
    <dbReference type="EnsemblBacteria" id="EEZ40717">
        <property type="protein sequence ID" value="EEZ40717"/>
        <property type="gene ID" value="VDA_001749"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4771">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="71288at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039426">
        <property type="entry name" value="BtuB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30069">
        <property type="entry name" value="PTHR30069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="4" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0675">Receptor</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="5 8" id="KW-0798">TonB box</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019818" evidence="9">
        <location>
            <begin position="21"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="11">
        <location>
            <begin position="51"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="10">
        <location>
            <begin position="181"/>
            <end position="648"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ40717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="684" mass="77859" checksum="1D0448730C5D5749" modified="2010-01-19" version="1">MLRYHLYPISLLFISATATSSELEDLLAMTLTNLSEQTVTVTSAAKKEQDLTDVPAAMYVITNDQIRRSGARSVPEALALAPGVQVTKISEFNWQVSLRGLNEVLFNKLLVMVDGRSVFSPLMSGTFWNTIDTLLEDIDRIEVLRGTAGTMWGGNAANGVINIITKNSRETLGHYGELATGEYHYQQADYRYGFLINDHTTARFSVKGLKSDYYTINEDEWHSYQGNFRLDYVNDEHTLSLHGGGYHNKSKHKWYTYTFADQIYLNIIDFNDYSRGGYINVDYLHQDDGQQIEGQVWASTNSKVEPSSQGTYQTIDGNILLRQQIKNNHELTVGGGIRFTHLSVAGVPDDMFTHQYPIYRYSYDQTQHEVIYNALLQSEWLFTPNIIGTLGVKVEHFTRNDSTEIQPQARILYKPKPEHQIWSGIGRAVVTPSMVDLASHDYRYVAVGTSNGYFPGILFTQPDPNMENESVITWDVGYRFNRLDFTFDSTLFYSQYDNVRMLRDINWHCIYGQCEDGTTQPNYAFVGSQQYSDALELSTYGIELYSSWQALPNFTINGSYSFIETDASCTGSNSCIRDDVGGYRLVYENQPNHYLSLQTLWDINDSWQLDLWLKHRGSVSSPNQASRSPDLTTIDLRLAWQKKPSWPRVEFIVDSLGSSSYSDASDSSPFIEESAFVRLSWNQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXV6</accession>
    <name>D0YXV6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002119</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299485.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41087">
        <property type="protein sequence ID" value="EEZ41087"/>
        <property type="gene ID" value="VDA_002119"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018713" evidence="1">
        <location>
            <begin position="24"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="84" mass="8956" checksum="948D6E0F18565B58" modified="2010-01-19" version="1">MSMKPLFYAAIVAATTFSSMALAASASISWSGRVPSGEPVNVSTDGKVVTYEAWNKAQVEDLKNSSQFEVTPISKEVSLLSVKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXX2</accession>
    <name>D0YXX2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002135</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299516.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002135"/>
    <dbReference type="EnsemblBacteria" id="EEZ41103">
        <property type="protein sequence ID" value="EEZ41103"/>
        <property type="gene ID" value="VDA_002135"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5033PIW">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="169550at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="299"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="1004" mass="113924" checksum="157661DD08075DF6" modified="2010-01-19" version="1">MIDKIDMASDDSSANYPVVILPAADKQPIGAEQNLFPKHIMTCEKESKVKKYKDIAYFIEGDAFYLMDETAVQYLEDAESKFKARFKGKDSTNVMPSLSQAGILDGLLSATLTSFIADEDKLLFQETEHWLSHQQKHLQNASSAYEASALVNQKREIHKRILAKAQQNAKDQGYIFDDGKLYSPKEPKIRKAIKAYQKAREAFLKQSELTPQAQIDDLKKRLQALNKVYSNAQYQVGDAVEYYKAHLIKQTANAEKHKEALEKSIEDLSVCGIATPELALAGQDKSKGHEYYALYFDYLKRAKKQEEVLNEKLKALLKSTNNFALPPNQILKEEYKQLKALEKEALKIHLQAITNILNMSSSLFLLWDIEDYRPKPLKYIVKGDFPLREYILGGSNSNQKDGLRYCSLIDIPQPEAKGNKLISAEEKSDYAIIEMLGDYLQELPIEDGWFGDDGVFDSKAFYKTLSDKHIEVESLKENSKVWEQAISEVLFSRDLKARLSPFDDSKQAQALRMTVASTQSGLSNPLDIVVGNESHDSGSTNKMEMLPLEAKTELILAKGEVNIFKMLTGKPLIKIPEAITKQDRDLVIPVKYEHNGVQKLTKFQCGAIQAQFYCKAWGFAGANLILGGKVELNAGGLSIPKLYEVNDDEVSFKGVKFEMGLKAGVEIGGFIFWYPPSGYPEYLIDKDSSAHSLMKGVFKIEKSKMVELPFRFRFVDKKLLIGVRFGPPSVGLAFEGAINPTMIGAWIWQFQRLLRQAHYRRIDIVADDETFKQLSLLSKGILYSQLNIGLFLAKQKDTYDNILDIFEQSSAGLVAYTLINGDETILSEWMRLMIPEALGPLLFTLVSSPKKFNIVDSNNNRIKIEIDEALLMQQLALCKVIHWLGNDHIMSVEKKAATRQMQKALERMNPYSKASQSEDVKKNDFLVNRRTILKFMEKDFNVDMDKPYNIDHSMKLYKYSNNGMFYTEFDALTVKLFDAYYTDRDVYANAAFDEGLSHVNNGRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXZ8</accession>
    <name>D0YXZ8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC-type tungstate transport system permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_002161</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299568.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002161"/>
    <dbReference type="EnsemblBacteria" id="EEZ41129">
        <property type="protein sequence ID" value="EEZ41129"/>
        <property type="gene ID" value="VDA_002161"/>
    </dbReference>
    <dbReference type="GeneID" id="57341698"/>
    <dbReference type="eggNOG" id="COG4662">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1110665at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="20"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="59"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="200"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="25"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="233" mass="25302" checksum="C13E6680A30D6037" modified="2010-01-19" version="1">MNIWQTTQQAIELLFSGDTALWGIVGVSFSVSLLAIGIVLVPSLLIAFALAYGKFPGRWLTLSLFNTFQSIPTVVIGLLLYMLLSRSGPLGDWQMLFTQKAMILGQILICLPILVSMMHAAFQNSDRRAWETSLTLGASYPRAFASLMWECRFPLLAAVIASFSRVITEVGCSMMVGGNIMNSTRNIPTAIALESSKGAFAQGVALGMVLLILALVLNFLLSISRGKAHLRTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY41</accession>
    <name>D0YY41_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hypothetical periplasmic protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002204</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299645.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002204"/>
    <dbReference type="EnsemblBacteria" id="EEZ41172">
        <property type="protein sequence ID" value="EEZ41172"/>
        <property type="gene ID" value="VDA_002204"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG50306J6">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1680433at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016896">
        <property type="entry name" value="DUF2860"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11059">
        <property type="entry name" value="DUF2860"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028696">
        <property type="entry name" value="UCP028696"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019231" evidence="1">
        <location>
            <begin position="22"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="329" mass="37187" checksum="610929B720457148" modified="2010-01-19" version="1">MKLQYIALTVSTLAFTTAVQAKGNSWEPGFSGDISVVTAYTSTNSQFDKDNSVTHDLSGSGSHQNHVFIAPLGTVSYTFSQADKQIFFGTSRSDVALGRFHIEAGYKQRFADRTQLTLSYIPGILEQDTWSDPFVINQSRDKTKSKVEAFRLQLDNIMGSPFSVQSAYGKYSVDNERSGWYQTNLTPAQRSSLRRDSDLFYLEGAYTKPLTQNTVLRTAINYRNINADGKAMSNNSYGVTSTVIQRLDRSSYAFTLSYKYTDFDSTNPIFSKTQENNEFGAFLAYEYAQPFDWKDWGFVSLLGYQNDNSNINFYDQDNILLSVGMNYQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYB1</accession>
    <name>D0YYB1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">BarA-associated response regulator UvrY</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_002274</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299769.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002274"/>
    <dbReference type="EnsemblBacteria" id="EEZ41242">
        <property type="protein sequence ID" value="EEZ41242"/>
        <property type="gene ID" value="VDA_002274"/>
    </dbReference>
    <dbReference type="GeneID" id="57341549"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="3"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="142"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="214" mass="23918" checksum="4F1BE0D050D150C4" modified="2010-01-19" version="1">MINVFLVDDHELVRTGIRRLLEDVRGIKVVGEADSGEDAVKWCRANHADIILMDMNMPGIGGLEATRKILRFNPDVKIIVLTVHTENPFPTKVMQAGASGYLTKGAGPDEMVNAIRMVNSGQRYISPEIAQQMALSQFASNSENPFKDLSERELQIMMMITKGQKVTDISEQLSLSPKTVNSYRYRLFNKLDISGDVELTHLAIRHGMLDTETL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYC7</accession>
    <name>D0YYC7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC-type multidrug transport system ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_002290</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299797.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002290"/>
    <dbReference type="EnsemblBacteria" id="EEZ41258">
        <property type="protein sequence ID" value="EEZ41258"/>
        <property type="gene ID" value="VDA_002290"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1131">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1926714at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="6"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="308" mass="33859" checksum="27E88480393FFB74" modified="2010-01-19" version="1">MSDLAIYASELTKQFGDFTAVDNLNLQVPKGSIYGFLGPNGCGKSTTLRMLTGLLQPSSGKVEVLGLEIPKQAEKLRLQLGYMTQKFSLYEDLTVKENLQFIGQIFGMGPKALKQRLDSQLVTYGLDTKSKQRAGSMSGGQKQRLALAAATMHSPKLLLLDEPTSAVDPENRREFWEQLFDLSDQGTTILVTTHYMDEAERCHGLAIMEAGVVRADGSPEQLMTQMGVTVVEVKAPGLRQLKELCLQKAEVRSAAQLGIRLRVLINNSVSDPIGWLQQQFPQLQQAEITLARPSLEDVFVTSTGSGRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYE0</accession>
    <name>D0YYE0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Predicted L-lactate dehydrogenase Iron-sulfur cluster-binding subunit YkgF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_002303</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002303"/>
    <dbReference type="EnsemblBacteria" id="EEZ41271">
        <property type="protein sequence ID" value="EEZ41271"/>
        <property type="gene ID" value="VDA_002303"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1139">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019516">
        <property type="term" value="P:lactate oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004452">
        <property type="entry name" value="4Fe-4S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024569">
        <property type="entry name" value="4Fe-4S-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024185">
        <property type="entry name" value="FTHF_cligase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003741">
        <property type="entry name" value="LUD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47153">
        <property type="entry name" value="PTHR47153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11870">
        <property type="entry name" value="DUF3390"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13183">
        <property type="entry name" value="Fer4_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02589">
        <property type="entry name" value="LUD_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00273">
        <property type="entry name" value="TIGR00273"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="LUD_dom" evidence="7">
        <location>
            <begin position="53"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="9">
        <location>
            <begin position="294"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3390" evidence="8">
        <location>
            <begin position="379"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF11870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ41271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="454" mass="50498" checksum="231AF4842DEA4DCF" modified="2010-01-19" version="1">MQDEFMLKSVANAQERMFKNRAIAAEKLGNWEEWREMGMDIRNHVLENLDYYLQQLSDNVQKNGGHVFFARTAEEATNYVENIIKQKNAKKVVKSKSMVTEEISLNKIIERNDCDVVETDLGEYILQVDDCDPPSHIVVPALHKNRDQIRDIFNDKLGYEGTSDPEEMTRFVRNHIRHDFLEADIGITGCNFAVAESGTISLVTNEGNARLATSLPKTHIAVMGMERIVPTFEELDIVVSLLCRSAVGLPLTGYVTALTGPREADQIDGPEEFHLVILDNGRSDILGSEFRAILRCVRCAACVNTCPAYRHIGGQSYGSIYSGPIGAVLSPLLGGYDDFKDLPYACSLCKACHDVCPVKIPLSDLLLKHRQKMGELKITPTAERASVGAFNFINARPILWDTAVKVGAKAASVMIKDGKMPFTAGPLAEWTEARDLPTPTGESFRSWFKKRNQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYK9</accession>
    <name>D0YYK9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">Ribonucleoside-diphosphate reductase</fullName>
            <ecNumber evidence="4 12">1.17.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">VDA_002372</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>[thioredoxin]-disulfide + a 2'-deoxyribonucleoside 5'-diphosphate + H2O = [thioredoxin]-dithiol + a ribonucleoside 5'-diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23252"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:73316"/>
            <dbReference type="EC" id="1.17.4.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 12">Genetic information processing; DNA replication.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the ribonucleoside diphosphate reductase large chain family.</text>
    </comment>
    <dbReference type="EC" id="1.17.4.1" evidence="4 12"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299977.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002372"/>
    <dbReference type="EnsemblBacteria" id="EEZ41340">
        <property type="protein sequence ID" value="EEZ41340"/>
        <property type="gene ID" value="VDA_002372"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0209">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="357568at2"/>
    <dbReference type="UniPathway" id="UPA00326"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004748">
        <property type="term" value="F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005144">
        <property type="entry name" value="ATP-cone_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013346">
        <property type="entry name" value="NrdE_NrdA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000788">
        <property type="entry name" value="RNR_lg_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013509">
        <property type="entry name" value="RNR_lsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008926">
        <property type="entry name" value="RNR_R1-su_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039718">
        <property type="entry name" value="Rrm1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11573">
        <property type="entry name" value="PTHR11573"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03477">
        <property type="entry name" value="ATP-cone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02867">
        <property type="entry name" value="Ribonuc_red_lgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00317">
        <property type="entry name" value="Ribonuc_red_lgN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01183">
        <property type="entry name" value="RIBORDTASEM1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48168">
        <property type="entry name" value="SSF48168"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02506">
        <property type="entry name" value="NrdE_NrdA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51161">
        <property type="entry name" value="ATP_CONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00089">
        <property type="entry name" value="RIBORED_LARGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6 12" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 12 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-cone" evidence="13">
        <location>
            <begin position="5"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEZ41340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="755" mass="85035" checksum="1F9288BC5E5ED00B" modified="2010-01-19" version="1">MTQQLTVTKRDGRTETLDLDKIHRVLDWAAEGLENVSVSQVELKSHIQFYDGMRTEDIHETIIKAAADLISEETPDYQYMAARLAIFHLRKKAYGQFEPPTLYKHVSHLVEQGKYDKHLLEDYTEEEFAVIDTFIDHWRDMNFSYAAVKQLEGKYLVQNRVSGEIFESAQFLYVLIAACLFAKYPKETRLDYIKRFYDAASTFKISLPTPIMSGVRTPTRQFSSCVLIECDDSLDSINATASSIVRYVSQRAGIGINAGRIRALGSEIRGGEAFHTGCIPFYKYFQTAVKCCSQGGVRGGAATLFYPLWHREVESLLVLKNNRGVEENRVRHMDYGVQINKLMYTRLIKGENISLFSPSDVPGLYDAFFADQVEFERLYTQYEQDESIKKQSVKAIDLFSLLMQERASTGRIYVQNVDHCNTHSPFDPSVAPIRQSNLCLEIALPTKPLNNVEDENGEIALCTLSAFNLGAIDSLDDLEELAELTVRALDALLDYQDYPLPAARRSTMNRRTLGVGVINFAYYLAKNGVRYSDGSANNLTHEAFEAIQYYLLKASLGLAKEQGACPAFNETTYAQGILPIDTYKKDIDKICSAELRYDWETLREEIKTHGLRNSTLSALMPSETSSQISNATNGIEPPRGYVSVKASKDGILKQVVPEYTKYKDNYELLWNIGGNDGYLQLVGIMQKFIDQAISANTNYDPSRQPGGKVPMKLLLKDLLTAYKLGVKTLYYHNTRDGASDSQGDMGADDCTSCKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYL3</accession>
    <name>D0YYL3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">META domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002376</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299984.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002376"/>
    <dbReference type="EnsemblBacteria" id="EEZ41344">
        <property type="protein sequence ID" value="EEZ41344"/>
        <property type="gene ID" value="VDA_002376"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3126">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3187">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2029962at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005184">
        <property type="entry name" value="DUF306_Meta_HslJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038670">
        <property type="entry name" value="HslJ-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039366">
        <property type="entry name" value="Pilotin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03724">
        <property type="entry name" value="META"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09619">
        <property type="entry name" value="YscW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018732" description="META domain-containing protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="META" evidence="2">
        <location>
            <begin position="178"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="291" mass="31492" checksum="7A0054957CF54B6D" modified="2010-01-19" version="1">MTFKMKKIALASSVALSALFLQACNDAKAPEQPTSVEQPAAVSQAVDTTAKAQAMKTLDVNVIYLDRRMLPPGAELTVVLEDVSKADAPADVMATESMKPAGAPPYAVALKYDANKLAEKHRYNVRATIKMKDQLIMTSTEALDPFAADVKQPVEVKLTRVTPAHNSVEKAAEQKANASFTNTYWKLMTLDGKEAQLGAGDKELFVQFNDDGLKGFSGCNSFMGTYQAKEGKLTLGPVAATQKMCVKGMEQEGTYLKAINEMASYSVTGETLTVKNNKGHVVATFESRYMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYR9</accession>
    <name>D0YYR9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cell division coordinator CpoB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">cpoB</name>
        <name evidence="5" type="ORF">VDA_002432</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the CpoB family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300080.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002432"/>
    <dbReference type="EnsemblBacteria" id="EEZ41400">
        <property type="protein sequence ID" value="EEZ41400"/>
        <property type="gene ID" value="VDA_002432"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1729">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1099900at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043093">
        <property type="term" value="P:FtsZ-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070206">
        <property type="term" value="P:protein trimerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02066">
        <property type="entry name" value="CpoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034706">
        <property type="entry name" value="CpoB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014162">
        <property type="entry name" value="CpoB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032519">
        <property type="entry name" value="YbgF_tri"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16331">
        <property type="entry name" value="TolA_bind_tri"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13174">
        <property type="entry name" value="TPR_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02795">
        <property type="entry name" value="tol_pal_ybgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="1" id="KW-0574">Periplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5009991134" description="Cell division coordinator CpoB" evidence="1">
        <location>
            <begin position="29"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="TolA_bind_tri" evidence="4">
        <location>
            <begin position="29"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="160"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="196"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="89"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="244" mass="27362" checksum="960DB2951E076C9C" modified="2010-01-19" version="1" precursor="true">MNSNNMRKLALGLLVGAATQLVAVPAFADSQLDRLERMLDARNQMMLDMQRQLDQISTDVDDLRGKVERNSYDLKQMLERQRELYREVDTLSSQQAQQAKETKATNTDAKENQESYSSNLDENQAYEKAVNLILKEKDYQGATKAFNDFIATYPKSVYAPNAHYWLGQLYFAQGQMKAADEHFTAVVAAKDSSKRADALLKLGAIAQKANDNAKATQYYQQVVKEFPSSTTATQAQAALNKLGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYS7</accession>
    <name>D0YYS7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Putative N-acetylmannosamine-6-phosphate 2-epimerase</fullName>
            <ecNumber evidence="5">5.1.3.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">ManNAc-6-P epimerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">nanE</name>
        <name evidence="6" type="ORF">VDA_002440</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 5">Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>an N-acyl-D-glucosamine 6-phosphate = an N-acyl-D-mannosamine 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:23932"/>
            <dbReference type="ChEBI" id="CHEBI:57599"/>
            <dbReference type="ChEBI" id="CHEBI:57666"/>
            <dbReference type="EC" id="5.1.3.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 5">Amino-sugar metabolism; N-acetylneuraminate degradation; D-fructose 6-phosphate from N-acetylneuraminate: step 3/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the NanE family.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.9" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300094.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002440"/>
    <dbReference type="EnsemblBacteria" id="EEZ41408">
        <property type="protein sequence ID" value="EEZ41408"/>
        <property type="gene ID" value="VDA_002440"/>
    </dbReference>
    <dbReference type="GeneID" id="57341341"/>
    <dbReference type="eggNOG" id="COG3010">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1710586at2"/>
    <dbReference type="UniPathway" id="UPA00629">
        <property type="reaction ID" value="UER00682"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047465">
        <property type="term" value="F:N-acylglucosamine-6-phosphate 2-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009385">
        <property type="term" value="F:N-acylmannosamine-6-phosphate 2-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006051">
        <property type="term" value="P:N-acetylmannosamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019262">
        <property type="term" value="P:N-acetylneuraminate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd04729">
        <property type="entry name" value="NanE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01235">
        <property type="entry name" value="ManNAc6P_epimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007260">
        <property type="entry name" value="NanE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36204">
        <property type="entry name" value="PTHR36204"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04131">
        <property type="entry name" value="NanE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="235" mass="24747" checksum="8C6D642196867EF9" modified="2010-01-19" version="1">MTHNEQPILKKLKGGFISSCQPVDNGPMDDPNIVAAMAQASVAGGAAGLRIEGVANLKAVRPTVTVPIIGIIKRDLPDSPIRITPFIDDVIALKEAGADIIAIDATHRTRPVEIAALVQEIKAQGCLVMADCSNYDEGIYCQQLGVDIIGSTMSGYTGGEVPTEPDVELVTRLHNAGCWVMAEGRYNTPELAKVAIEAGASCVTVGSAITRVEHICQWFSSAVASAEPQKIEAIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ01</accession>
    <name>D0YZ01_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="15">PTS system N-acetylglucosamine-specific</fullName>
            <ecNumber evidence="15">2.7.1.69</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">VDA_002514</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.7.1.69" evidence="15"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002514"/>
    <dbReference type="EnsemblBacteria" id="EEZ41482">
        <property type="protein sequence ID" value="EEZ41482"/>
        <property type="gene ID" value="VDA_002514"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1263">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1264">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019866">
        <property type="term" value="C:organelle inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103111">
        <property type="term" value="F:D-glucosamine PTS permease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015572">
        <property type="term" value="F:N-acetylglucosamine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008982">
        <property type="term" value="F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00212">
        <property type="entry name" value="PTS_IIB_glc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036878">
        <property type="entry name" value="Glu_permease_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018113">
        <property type="entry name" value="PTrfase_EIIB_Cys"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003352">
        <property type="entry name" value="PTS_EIIC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013013">
        <property type="entry name" value="PTS_EIIC_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001996">
        <property type="entry name" value="PTS_IIB_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010974">
        <property type="entry name" value="PTS_IIBC_nag"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00367">
        <property type="entry name" value="PTS_EIIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02378">
        <property type="entry name" value="PTS_EIIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55604">
        <property type="entry name" value="SSF55604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00826">
        <property type="entry name" value="EIIB_glc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01998">
        <property type="entry name" value="PTS-II-BC-nag"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51098">
        <property type="entry name" value="PTS_EIIB_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01035">
        <property type="entry name" value="PTS_EIIB_TYPE_1_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51103">
        <property type="entry name" value="PTS_EIIC_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0598">Phosphotransferase system</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="5 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="33"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="68"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="230"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="263"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="285"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="314"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="337"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="domain" description="PTS EIIC type-1" evidence="14">
        <location>
            <begin position="1"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="domain" description="PTS EIIB type-1" evidence="13">
        <location>
            <begin position="388"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphocysteine intermediate; for EIIB activity" evidence="11">
        <location>
            <position position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEZ41482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="475" mass="50152" checksum="F40F5E0CDC9EA026" modified="2010-01-19" version="1">MVPVAVLPAAAILMGIGYWIDPTGWGSNSAIAAFLIKAGAAIIDNMSVLFAVGVAYGMSKDKDGAAALSGFVGFLVVTTLLAPGAVAQIQGIDPSAVPAAFSKINNQFVGILVGIVSAELYNRFSDVQLHKALAFFSGKRLVPILTSVAGIVIAGVLMFVWPSIYGGLVHFGETIQGMGSVGAGIYAFFNRLLIPVGLHHALNSVFWFDVAGINDIPNFLSGKGVPGVTGMYQAGFFPVMMFGLPGAALAMYHTAKLKNKERVASLLLAAGFASFFTGVTEPLEFAFMFLAPVLYVIHAVLTGLSVYIAASMQWIAGFGFSAGLVDMVLSSRNPLAVQWYILIIQGIGFFCIYYAVFRFAIVKFNLKTPGREDDEAEETSGAAAAETGELAKQYIKALGGRDNLENIDACITRLRLTLKDSSLADEKTLKALGAMGVVKLGTNNLQVILGPLAEIVAGEMKKVSPAEDLSSVKLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ02</accession>
    <name>D0YZ02_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glucosamine-6-phosphate deaminase</fullName>
            <ecNumber evidence="1">3.5.99.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">GlcN6P deaminase</fullName>
            <shortName evidence="1">GNPDA</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Glucosamine-6-phosphate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">nagB</name>
        <name evidence="3" type="ORF">VDA_002515</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:12172"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:75989"/>
            <dbReference type="EC" id="3.5.99.6"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="1">Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-sugar metabolism; N-acetylneuraminate degradation; D-fructose 6-phosphate from N-acetylneuraminate: step 5/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homohexamer; trimer of disulfide-linked dimers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.5.99.6" evidence="1"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300234.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002515"/>
    <dbReference type="EnsemblBacteria" id="EEZ41483">
        <property type="protein sequence ID" value="EEZ41483"/>
        <property type="gene ID" value="VDA_002515"/>
    </dbReference>
    <dbReference type="GeneID" id="57341256"/>
    <dbReference type="eggNOG" id="COG0363">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1828393at2"/>
    <dbReference type="UniPathway" id="UPA00629">
        <property type="reaction ID" value="UER00684"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004342">
        <property type="term" value="F:glucosamine-6-phosphate deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006044">
        <property type="term" value="P:N-acetylglucosamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019262">
        <property type="term" value="P:N-acetylneuraminate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01399">
        <property type="entry name" value="GlcN6P_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01241">
        <property type="entry name" value="GlcN6P_deamin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006148">
        <property type="entry name" value="Glc/Gal-6P_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004547">
        <property type="entry name" value="Glucosamine6P_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018321">
        <property type="entry name" value="Glucosamine6P_isomerase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11280">
        <property type="entry name" value="PTHR11280"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01182">
        <property type="entry name" value="Glucosamine_iso"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00502">
        <property type="entry name" value="nagB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01161">
        <property type="entry name" value="GLC_GALNAC_ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="1" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucosamine_iso" evidence="2">
        <location>
            <begin position="17"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for enolization step" evidence="1">
        <location>
            <position position="72"/>
        </location>
    </feature>
    <feature type="active site" description="For ring-opening step" evidence="1">
        <location>
            <position position="141"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for ring-opening step" evidence="1">
        <location>
            <position position="143"/>
        </location>
    </feature>
    <feature type="active site" description="For ring-opening step" evidence="1">
        <location>
            <position position="148"/>
        </location>
    </feature>
    <feature type="site" description="Part of the allosteric site" evidence="1">
        <location>
            <position position="151"/>
        </location>
    </feature>
    <feature type="site" description="Part of the allosteric site" evidence="1">
        <location>
            <position position="158"/>
        </location>
    </feature>
    <feature type="site" description="Part of the allosteric site" evidence="1">
        <location>
            <position position="160"/>
        </location>
    </feature>
    <feature type="site" description="Part of the allosteric site" evidence="1">
        <location>
            <position position="161"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Interchain" evidence="1">
        <location>
            <position position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="266" mass="29979" checksum="D2BB2B0DE3A15AC7" modified="2010-01-19" version="1">MRLIPLDNAKDVGLWSARYIADRINKFQPTAERPFVLGLPTGGTPLATYKRLIELYEAGEVSFKHVVTFNMDEYVGMPSDHPESYRSFMYNNFFNHIDIQEENINLLDGNAADHVAECQRYEDKIKSYGRINLFMGGVGNDGHIAFNEPASSLSSRTRIKTLTHDTRIANSRFFDGDINQVPKYSLTIGVGTLLDSEEIMILVTGHNKAQALEAAVEGCVNHLWTISALQLHPKSLIVCDEPATQELKVKTVKYFQELEAENINHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ19</accession>
    <name>D0YZ19_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Porin-like protein H</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_002532</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell outer membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300270.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002532"/>
    <dbReference type="EnsemblBacteria" id="EEZ41500">
        <property type="protein sequence ID" value="EEZ41500"/>
        <property type="gene ID" value="VDA_002532"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1064531at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015288">
        <property type="term" value="F:porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033900">
        <property type="entry name" value="Gram_neg_porin_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13609">
        <property type="entry name" value="Porin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019253" evidence="3">
        <location>
            <begin position="20"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="domain" description="Porin_4" evidence="4">
        <location>
            <begin position="7"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="334" mass="36731" checksum="FA045147AB158C9A" modified="2010-01-19" version="1">MKKTLLALAVMTAAGSANAAINVYDNNGVKVDLSGAAEVQYFDGFEKSKDATIRLDDGDFAINATYAINENLNVISGMAFKYESRDVQNDELWVGFSSNQMGALTFGRQLLVSDDSGIGKDYELGLEQVDFAQTEGDRVIKYVYDNGSFYAAASHELNADHSTTITDGRLGFRTNGLDVRVYGYDGERIGAKGLELGITPDQKPIVKPGEAGEDIRGYNLEAEYGFGAFNIAASFGQIEYKAADTHVTDRDLDLYEINGSYTMDKTTFALGYVHAQNHANTEKYGKRHDNVYANVTQQLHSNVKVYAEVGYADNDKIINDREEFGYVAGMEVKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ30</accession>
    <name>D0YZ30_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Membrane fusion component of tripartite multidrug resistance system</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_002543</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300292.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002543"/>
    <dbReference type="EnsemblBacteria" id="EEZ41511">
        <property type="protein sequence ID" value="EEZ41511"/>
        <property type="gene ID" value="VDA_002543"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1566">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1680841at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043602">
        <property type="entry name" value="CusB_dom_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00529">
        <property type="entry name" value="CusB_dom_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="5">
        <location>
            <begin position="47"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="CusB_dom_1" evidence="4">
        <location>
            <begin position="281"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="147"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="347" mass="37207" checksum="59859E78D9C85C01" modified="2010-01-19" version="1">MNETKSHFARNLIVTGLIAAGLATAGYFYVKHQEEYPSTDDAYVHANIVYVAPQVSGKVISSNVTDYQTVSKGDLLVQIDPAPYQAQLDEAKAAYELATQNNAATDDAILAASANVKTAMAQLNDAQSTYRRIKDLVNKKLYPQQELDDAKAKLSTAENNVEAARANMSQLIKSQGAKGKDAPEVKKAAAALSQASLSLSYTNIFADHDGKLGKVSVHPGSVVAPGQALMPLVEANTYWVQANFKEDQVGRMHIGMPATIELDLYPDIDFHGTIAAISPASGSSFSLLPPENATGNWVKVPQRFPVLIELNNEQENKAHPLRVGASATVTVDTLAKTDDAQVAQQGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ69</accession>
    <name>D0YZ69_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative SOJ-like and chromosome partitioning protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002582</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300390.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002582"/>
    <dbReference type="EnsemblBacteria" id="EEZ41550">
        <property type="protein sequence ID" value="EEZ41550"/>
        <property type="gene ID" value="VDA_002582"/>
    </dbReference>
    <dbReference type="GeneID" id="57341176"/>
    <dbReference type="eggNOG" id="COG1192">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="729012at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025669">
        <property type="entry name" value="AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13614">
        <property type="entry name" value="AAA_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_31" evidence="1">
        <location>
            <begin position="3"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="258" mass="28954" checksum="7A896477B4D06B54" modified="2010-01-19" version="1">MIVWSIANQKGGVGKTTTTVTLAGLLSERKQRVLLVDTDPHASLTTYLNFDPDAVTASLFDLFQLPEITRDRVKPLILHTDYPNIDIIPAHMSLATLDRVLGNRSGMGLVVKKALNSLAQDYDYVLIDCPPILGVMMVNALAASDRILIPVQTEFLAMKGLERMMRTLDIMQRSRPAGFNVCVVPTMYDRRTNASLQTLQELKERYPEQVWASAVPIDTKFRDASLRHMPPSLYAKSCRGVFAYKTLLNHLERLEHGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ90</accession>
    <name>D0YZ90_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Flagellar regulatory protein FleQ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_002603</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002603"/>
    <dbReference type="EnsemblBacteria" id="EEZ41571">
        <property type="protein sequence ID" value="EEZ41571"/>
        <property type="gene ID" value="VDA_002603"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2204">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002197">
        <property type="entry name" value="HTH_Fis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025943">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025944">
        <property type="entry name" value="Sigma_54_int_dom_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02954">
        <property type="entry name" value="HTH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00158">
        <property type="entry name" value="Sigma54_activat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01590">
        <property type="entry name" value="HTHFIS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00676">
        <property type="entry name" value="SIGMA54_INTERACT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00688">
        <property type="entry name" value="SIGMA54_INTERACT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50045">
        <property type="entry name" value="SIGMA54_INTERACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0966">Cell projection</keyword>
    <keyword evidence="7" id="KW-0969">Cilium</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0282">Flagellum</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="6">
        <location>
            <begin position="1"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="309" mass="34950" checksum="B1A3630C4D34B322" modified="2010-01-19" version="1">MVARNIHYHSSRGKGPFVPVNCGAIPPDLLESELFGHEKGAFTGAIAARKGRFELAEGGTLFLDEIGDMPMSMQVKLLRVLQERCFERVGGNQTIQANVRIVAATHRNLDEMIANSKFREDLYYRLNVFPIEMPALRERIEDIPLLLQELLARMEAEGANVVHFTPRAITSLMEHKWPGNVRELANLVERLIILYPGEMVDVNHLPMSYRHTDLPEFHPEPHVTLEQMEQEALADIFAESNDDANSLSDLPPEGLNLKEMLADLEIDMIRQALEAQNGVVARAADMLGMRRTTLVEKMRKYGLSKDDIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZE9</accession>
    <name>D0YZE9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribosomal RNA large subunit methyltransferase G</fullName>
            <ecNumber evidence="1">2.1.1.174</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">23S rRNA m2G1835 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">rRNA (guanine-N(2)-)-methyltransferase RlmG</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rlmG</name>
        <name evidence="3" type="ORF">VDA_002662</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>guanosine(1835) in 23S rRNA + S-adenosyl-L-methionine = H(+) + N(2)-methylguanosine(1835) in 23S rRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42744"/>
            <dbReference type="Rhea" id="RHEA-COMP:10217"/>
            <dbReference type="Rhea" id="RHEA-COMP:10218"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74481"/>
            <dbReference type="EC" id="2.1.1.174"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. RlmG family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.174" evidence="1"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300639.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002662"/>
    <dbReference type="EnsemblBacteria" id="EEZ41630">
        <property type="protein sequence ID" value="EEZ41630"/>
        <property type="gene ID" value="VDA_002662"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2813">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1027015at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052916">
        <property type="term" value="F:23S rRNA (guanine(1835)-N(2))-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01859">
        <property type="entry name" value="23SrRNA_methyltr_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017237">
        <property type="entry name" value="rRNA_m2G-MeTrfase_RsmD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007848">
        <property type="entry name" value="Small_mtfrase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47816:SF5">
        <property type="entry name" value="PTHR47816:SF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05175">
        <property type="entry name" value="MTS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037565">
        <property type="entry name" value="RRNA_m2G_Mtase_RsmD_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MTS" evidence="2">
        <location>
            <begin position="200"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="374" mass="41946" checksum="F86EBF85DD06AE2F" modified="2010-01-19" version="1">MKLELSLHDRTLLLGRYPARKNETLQAWDAADEYLINHIQDLILDPERPILILNDSFGALSCWFADKAPVISMTDSFVAKQGHLENLAANTLPPVTLLSCLDELPHNPQLVLVKLPKSTRLLRWQLQQLCQALPQDCQVITAGKAKDIHSSTLKMFEKYLGETKTSLAIKKSRLIFTQVNKALIQALPEPVTWTVPEHQLTISNHANVFSGESLDIGGRFLLDHIPLNEKYKDIIDLGCGNGVIGIKAAQLNPQAKVICVDESFMAGASCRENADHNLTNPEQLTVKVGNCLDDFPFDSADLVLCNPPFHQQNAITDHIAWQMFCDGHKVLRHKGQMIVIGNRQLPYYDKLKRVFGKVSVIAQNKKFVIYQAEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZG7</accession>
    <name>D0YZG7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Riboflavin synthase alpha chain</fullName>
            <ecNumber evidence="4">2.5.1.9</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_002680</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.5.1.9" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300686.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002680"/>
    <dbReference type="EnsemblBacteria" id="EEZ41648">
        <property type="protein sequence ID" value="EEZ41648"/>
        <property type="gene ID" value="VDA_002680"/>
    </dbReference>
    <dbReference type="GeneID" id="57341051"/>
    <dbReference type="eggNOG" id="COG0307">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1276859at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004746">
        <property type="term" value="F:riboflavin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00402">
        <property type="entry name" value="Riboflavin_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023366">
        <property type="entry name" value="ATP_synth_asu-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001783">
        <property type="entry name" value="Lumazine-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026017">
        <property type="entry name" value="Lumazine-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21098">
        <property type="entry name" value="PTHR21098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00677">
        <property type="entry name" value="Lum_binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000498">
        <property type="entry name" value="Riboflavin_syn_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00187">
        <property type="entry name" value="ribE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51177">
        <property type="entry name" value="LUMAZINE_BIND"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="Lumazine-binding" evidence="2">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="Lumazine-binding" evidence="3">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="repeat" description="Lumazine-binding" evidence="2">
        <location>
            <begin position="98"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="Lumazine-binding" evidence="3">
        <location>
            <begin position="98"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="218" mass="23259" checksum="C3DF18C04583A5A5" modified="2010-01-19" version="1">MFTGIIEAVGTITALTPKGADISVTVDSGKLDLSDVKLGDSIATNGVCLTVVQLTGKGYVADLSLETLKRTAFANYKAGQAVNLEKAMLPTTRFGGHMVSGHVDAVAEVIERTHTGRAIEFWIKAPSHLAQYIAEKGSIAIDGISLTVNAIRGDEFKLTIVPHTAAETTMESFKVGRQINIEVDVIARYLERLMLGPKAAEKEPSVTMDLLARSGFLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZJ3</accession>
    <name>D0YZJ3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Peptidase B</fullName>
            <ecNumber evidence="8">3.4.11.23</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_002706</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M17 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.23" evidence="8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300756.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002706"/>
    <dbReference type="MEROPS" id="M17.004"/>
    <dbReference type="EnsemblBacteria" id="EEZ41674">
        <property type="protein sequence ID" value="EEZ41674"/>
        <property type="gene ID" value="VDA_002706"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0260">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="356206at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00433">
        <property type="entry name" value="Peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011356">
        <property type="entry name" value="Leucine_aapep/pepB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008330">
        <property type="entry name" value="Pept_M17_PepB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000819">
        <property type="entry name" value="Peptidase_M17_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11963">
        <property type="entry name" value="PTHR11963"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12404">
        <property type="entry name" value="DUF3663"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00883">
        <property type="entry name" value="Peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036388">
        <property type="entry name" value="Ctsl_amnpptdse_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00481">
        <property type="entry name" value="LAMNOPPTDASE"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00631">
        <property type="entry name" value="CYTOSOL_AP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0464">Manganese</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CYTOSOL_AP" evidence="7">
        <location>
            <begin position="272"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ41674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="425" mass="45522" checksum="3CBD80A5F84B6897" modified="2010-01-19" version="1">MLKVLLCAEASAELWGENALISYQSDAATIHYAGDYPLRRIQQAARRLQSQGVQNIQLEGDNWSYERQWAFYCGYTSPKASGILQWASIDEDELELLNARRHCADWLRKVVNATPDEMYPEQLADEVTQFLTGIAGDKISSQKIVGDELLNQGWVGIHSVGRASQRPPVMLTIDYNPTGDDNAPVSACLVGKGITFDSGGYSLKSSVGMLAMKSDMGGAATVAAALGYAIEQGLRQRVQLILCCAENLVAGNAYKLGDVLHYKNGVSVEVVNTDAEGRLVLADGLIAASKTQAPLIIDAATLTGAAVMALGEDYNAIFSLDKSLLLHAQGLSELVNEPAWPLPLEPWHQNHCPSDYADTANSRAQPGGGMGGASNAAAFLSRFVDTDQSRWIHFDLSAAFKEGSDARWGAGATGLGVANIAALLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZL0</accession>
    <name>D0YZL0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Isocitrate lyase</fullName>
            <ecNumber evidence="1">4.1.3.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Isocitrase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Isocitratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_002723</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>D-threo-isocitrate = glyoxylate + succinate</text>
            <dbReference type="Rhea" id="RHEA:13245"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
            <dbReference type="EC" id="4.1.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="8">Can also use Mn(2+) ion.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.1" evidence="1"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300821.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002723"/>
    <dbReference type="EnsemblBacteria" id="EEZ41691">
        <property type="protein sequence ID" value="EEZ41691"/>
        <property type="gene ID" value="VDA_002723"/>
    </dbReference>
    <dbReference type="GeneID" id="57341004"/>
    <dbReference type="eggNOG" id="COG2224">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="152545at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004451">
        <property type="term" value="F:isocitrate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00377">
        <property type="entry name" value="ICL_PEPM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039556">
        <property type="entry name" value="ICL/PEPM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006254">
        <property type="entry name" value="Isocitrate_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018523">
        <property type="entry name" value="Isocitrate_lyase_ph_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21631">
        <property type="entry name" value="PTHR21631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00463">
        <property type="entry name" value="ICL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001362">
        <property type="entry name" value="Isocit_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01346">
        <property type="entry name" value="isocit_lyase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00161">
        <property type="entry name" value="ISOCITRATE_LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="93"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="196"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="317"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="195"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="351"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00031022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00031921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001362-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001362-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001362-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="435" mass="47938" checksum="3A062D1BCAA8406F" modified="2010-01-19" version="1">MTLTRQQLIEAIEKDWAENPRWKNVKRTYSAEDVVNLRGSVLPEHTIAQRGADKLWDLINGSAKKGYVNCLGALTGGQAVQQAKAGIEAIYLSGWQVAADNNSASAMYPDQSLYPVDSVPAVVKRINNSFRRADQIQWANGVTPEEGVDYFLPIVADAEAGFGGVLNAYELMRHMIEAGAAGVHFEDQLASVKKCGHMGGKVLVPTQEAVQKLVAARLAADVAGTTTLVIARTDANAADLLTSDCDPYDKDFIVGERSSEGFYRVRAGIDQAIARGLAYAPYADMVWCETATPCLEEARKFAEAIHAQYPDQILAYNCSPSFNWEKNLDAKTIAEFQQALSDMGYKYQFITLAGIHNMWFNMFELAHAYAQGEGMRHYVEMVQRREFESADKGYTFVAHQQEVGTGYFDKMTNIIQGGNSSVTALTGSTEEDQFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-08-12" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZP0</accession>
    <name>D0YZP0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">L-seryl-tRNA(Sec) selenium transferase</fullName>
            <ecNumber evidence="5">2.9.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Selenocysteine synthase</fullName>
            <shortName evidence="5">Sec synthase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Selenocysteinyl-tRNA(Sec) synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">selA</name>
        <name evidence="8" type="ORF">VDA_002753</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>H(+) + L-seryl-tRNA(Sec) + selenophosphate = L-selenocysteinyl-tRNA(Sec) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:22728"/>
            <dbReference type="Rhea" id="RHEA-COMP:9742"/>
            <dbReference type="Rhea" id="RHEA-COMP:9743"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16144"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:78533"/>
            <dbReference type="ChEBI" id="CHEBI:78573"/>
            <dbReference type="EC" id="2.9.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 5 6">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5">Aminoacyl-tRNA biosynthesis; selenocysteinyl-tRNA(Sec) biosynthesis; selenocysteinyl-tRNA(Sec) from L-seryl-tRNA(Sec) (bacterial route): step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SelA family.</text>
    </comment>
    <dbReference type="EC" id="2.9.1.1" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300908.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002753"/>
    <dbReference type="EnsemblBacteria" id="EEZ41721">
        <property type="protein sequence ID" value="EEZ41721"/>
        <property type="gene ID" value="VDA_002753"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1921">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1124266at2"/>
    <dbReference type="UniPathway" id="UPA00906">
        <property type="reaction ID" value="UER00896"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004125">
        <property type="term" value="F:L-seryl-tRNASec selenium transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001514">
        <property type="term" value="P:selenocysteine incorporation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097056">
        <property type="term" value="P:selenocysteinyl-tRNA(Sec) biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00423">
        <property type="entry name" value="SelA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018319">
        <property type="entry name" value="SelA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004534">
        <property type="entry name" value="SelA_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025862">
        <property type="entry name" value="SelA_trans_N_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12390">
        <property type="entry name" value="Se-cys_synth_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03841">
        <property type="entry name" value="SelA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00474">
        <property type="entry name" value="selA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="5 6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0711">Selenium</keyword>
    <keyword evidence="5 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Se-cys_synth_N" evidence="7">
        <location>
            <begin position="7"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="5 6">
        <location>
            <position position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR618319-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ41721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="483" mass="53203" checksum="6D684299EC75488D" modified="2010-01-19" version="1">MTARALFAHLPSVDQIIHHPLQQALIAQYGKVHLTAMVRQLQQEARETIRTQQQLPSWLASSEPLVSKALILDRFSQHLTHALAPKHQQGLQRVFNLTGTILHTNLGRALQAEAAIKAVTQVMRYPSTLEYSLQNGQRGHRDHAISEQLQQLIGCEDACLVNNNAAAVLLMLAGTAAGKEVIVSRGELVEIGGSFRIPDVMRQAGCQLVEVGATNRTHLRDYQQAISEHTAALMKVHTSNYLIQGFTSSVAEADLCQLAHQHQLPVISDLGSGSLIDLSTYGLPTEPMPQQMLRDGIDLVSFSGDKLLGGPQAGIIAGRKDLIEQLQHHPLKRALRCDKMTLAALEATLNLYRHPEQLPCELPTLLRLTRTLDQLSEQAQQLLPYCHQLAGKDFTVTIEPSYGQIGSGSLPTEQLESIAISFQANHTSSRSLNDLDDLLRSGEIPIIGRVHHNKLWLCMRGLVDINDFITQLNQLSSTSEVMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZS4</accession>
    <name>D0YZS4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Site-specific DNA-methyltransferase (adenine-specific)</fullName>
            <ecNumber evidence="3">2.1.1.72</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_002787</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:15197"/>
            <dbReference type="Rhea" id="RHEA-COMP:12418"/>
            <dbReference type="Rhea" id="RHEA-COMP:12419"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90615"/>
            <dbReference type="ChEBI" id="CHEBI:90616"/>
            <dbReference type="EC" id="2.1.1.72"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the N(4)/N(6)-methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.72" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301005.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002787"/>
    <dbReference type="EnsemblBacteria" id="EEZ41755">
        <property type="protein sequence ID" value="EEZ41755"/>
        <property type="gene ID" value="VDA_002787"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0286">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="791672at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022749">
        <property type="entry name" value="D12N6_MeTrfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003356">
        <property type="entry name" value="DNA_methylase_A-5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038333">
        <property type="entry name" value="T1MK-like_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12161">
        <property type="entry name" value="HsdM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02384">
        <property type="entry name" value="N6_Mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HsdM_N" evidence="6">
        <location>
            <begin position="9"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="N6_Mtase" evidence="5">
        <location>
            <begin position="161"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="779"/>
            <end position="813"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="889" mass="100294" checksum="A8F42E20A1BB4E5A" modified="2010-01-19" version="1">MQKLTLNKLSSKLFKACDILRGKMDASEYKEYIFGILFLKRMSDQFHKDYQAKISELKKEGHDDDEIELLLEDEEQFDFFVPEKARWENLKHLKTNVGSGLNKALEALEESNTKKGLEGVLKHINFNRKVGKKPIPDERLVEFIQHFDSIPLSNSDFEFPDLLGAAYEYLIKYFADSAGKKGGEFYTPAEVVRLLVEILEPAEGMEIYDPTCGSGGMLIQSRNYVQETGGNVKKIHLFGQEDNGGTWSICKMNMILHGTGGADIENGDTLATPLHRTKDGEVRPFDRVIANPPFSQNYKKADMQLKERFNTFMPESGKKADLMFVQHMVASLKANGKAAVVMPHGVLFRGAEERTCRQDFIERGILEAVIGLPQGLFYGTGIPACVLVLNKAGCKKRDSVLYINADREYREGKNQNSLRPEDIEKITSVYKVMLEDEKHPGVEKYARLVHKDELAREDYNLNIRRYVDNSPAPEPQNVKAHLSGGIPTTEIDALQSTWNDYPGLKESLFVPRANNEFQDFADEFEALSSLKSHIESFPAVLKKHADFQAALDDWKQDFAGFEALGDKKLGDEGVFALRRESLNTIEKHLMPIKLLNQYKVRGALADWFKTLEADFKSVAASGWNAELIPDEVLFASQCADVVEELEIKQARISELQAFVDAADEEDYEPTDENPALPSEYVKQLKDELKEHKATIKTSLAVLKAQIKDAFTQLKSNAELPKGTKQGDFAKGLTGKEMNFAVHSEILALADELGVQLDNLELIKEHARKGAVAAAEATAIEAKFAAHKALEDELKQLKAEIKETEKRRDELLEIARDAITPEEAKVLILDRFKTELDRQYQSYVRALLLDRIAAIENLHRKYQVTAKSIIAKREQEANKLAGFMKELGYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZU4</accession>
    <name>D0YZU4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphoserine phosphatase</fullName>
            <ecNumber evidence="6">3.1.3.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">O-phosphoserine phosphohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">VDA_002807</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>H2O + O-phospho-D-serine = D-serine + phosphate</text>
            <dbReference type="Rhea" id="RHEA:24873"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:35247"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58680"/>
            <dbReference type="EC" id="3.1.3.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + O-phospho-L-serine = L-serine + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21208"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57524"/>
            <dbReference type="EC" id="3.1.3.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-serine biosynthesis; L-serine from 3-phospho-D-glycerate: step 3/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the HAD-like hydrolase superfamily. SerB family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.3" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301064.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002807"/>
    <dbReference type="EnsemblBacteria" id="EEZ41775">
        <property type="protein sequence ID" value="EEZ41775"/>
        <property type="gene ID" value="VDA_002807"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0560">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1755462at2"/>
    <dbReference type="UniPathway" id="UPA00135">
        <property type="reaction ID" value="UER00198"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036424">
        <property type="term" value="F:L-phosphoserine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006564">
        <property type="term" value="P:L-serine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004469">
        <property type="entry name" value="PSP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041449">
        <property type="entry name" value="SerB_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18429">
        <property type="entry name" value="DUF5609"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00029">
        <property type="entry name" value="phosphoserine_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00338">
        <property type="entry name" value="serB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0718">Serine biosynthesis</keyword>
    <feature type="domain" description="DUF5609" evidence="15">
        <location>
            <begin position="32"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="14">
        <location>
            <position position="112"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="14">
        <location>
            <position position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00009184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00015196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00031693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR604469-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF18429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EEZ41775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="333" mass="36581" checksum="B36315144B245ADD" modified="2010-01-19" version="1">MELSLSPLKIKKHAALYRRFPELQQASLRDKQQGQWILFGQDLSSLRIALIEEWAQQRLQLVAAWQVGDYDVLLIKNDLSDPIKAAVYRAECDFALTKDLPELNKPGLVVMDMDSTAIEMECIDEIAKLAGTGELVSAITEQAMQGELDFEQSLRQRVATLSGADEAILAQVLEQLPLMPELIELVRTLQAFGWKVAIASGGFTYFADQLKAMLDLDGVYANQLAIQDGKLIGEVVGSVVDADAKAYYLHQLSEQFEIEPHNTVAIGDGANDLAMMKAAGLGIAFHAKPKVQQQAQTAINYGSLGAVLCILSASLVPHHLSWKNQSCCQNIEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z003</accession>
    <name>D0Z003_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Single-stranded-DNA-specific exonuclease RecJ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_002866</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RecJ family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301240.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002866"/>
    <dbReference type="EnsemblBacteria" id="EEZ41834">
        <property type="protein sequence ID" value="EEZ41834"/>
        <property type="gene ID" value="VDA_002866"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0608">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="491634at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008409">
        <property type="term" value="F:5'-3' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001667">
        <property type="entry name" value="DDH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038763">
        <property type="entry name" value="DHH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003156">
        <property type="entry name" value="DHHA1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004610">
        <property type="entry name" value="RecJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041122">
        <property type="entry name" value="RecJ_OB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01368">
        <property type="entry name" value="DHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02272">
        <property type="entry name" value="DHHA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17768">
        <property type="entry name" value="RecJ_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64182">
        <property type="entry name" value="SSF64182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00644">
        <property type="entry name" value="recJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHH" evidence="6">
        <location>
            <begin position="70"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="DHHA1" evidence="7">
        <location>
            <begin position="319"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="domain" description="RecJ_OB" evidence="8">
        <location>
            <begin position="466"/>
            <end position="570"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="574" mass="62860" checksum="E8D0889E0B4476D0" modified="2010-01-19" version="1">MIEIKRRPEADISGFSDAIPARLKRIYASRGITHDGELERGAKGLLSYNQLHGMAQAVDLLEQALRNNQRIIIVSDFDADGATSSALSVLAFKMLGCQNVDYLVPNRFDDGYGLSPEVVDQALAKGVEVIMTVDNGVSSLSGVAYAKEKGLTVVVTDHHLPGDILPNADAIVNPNLNECGFPSKALCGVGVAFYLMLALRAQLRATDWFTQQNIPEPNLAELLDLVALGTVADVVALDGNNRILVHQGLQRIRAGRCRPGIQALIEVANRDPQKIVTSDLGFALGPRINAAGRLDDMAFGVELLLCDNIQSARRMATELDGLNQTRKEIEQGMKEEALAICERLKFSANDMPYGLVLFQKDWHQGVIGILASRIKEKFHRPVICFADAGNEQIKGSCRSIPGLHMRDVLDLIDTQNPGMIAKFGGHAMAAGLTIDTKQLDAFSRAFDQAVRNELGEDELKGVLLTDGELEANEFNLDTAEMLRAGGPWGQQFPEPTFDGTFRLLHQKLVGGKHLKMMVEPLHGGSVIDAIAFNVDLKRWPDASVQQVELVYRLDINEFRGNRSVQLMIEHLAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z005</accession>
    <name>D0Z005_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">Tyrosine recombinase XerD</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">xerD</name>
        <name evidence="15" type="ORF">VDA_002868</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the 'phage' integrase family. XerD subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301242.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002868"/>
    <dbReference type="EnsemblBacteria" id="EEZ41836">
        <property type="protein sequence ID" value="EEZ41836"/>
        <property type="gene ID" value="VDA_002868"/>
    </dbReference>
    <dbReference type="GeneID" id="57340842"/>
    <dbReference type="eggNOG" id="COG4974">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="745068at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009037">
        <property type="term" value="F:tyrosine-based site-specific recombinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01808">
        <property type="entry name" value="Recomb_XerC_XerD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01807">
        <property type="entry name" value="Recomb_XerD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044068">
        <property type="entry name" value="CB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004107">
        <property type="entry name" value="Integrase_SAM-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011932">
        <property type="entry name" value="Recomb_XerD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023009">
        <property type="entry name" value="Tyrosine_recombinase_XerC/XerD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02899">
        <property type="entry name" value="Phage_int_SAM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02225">
        <property type="entry name" value="recomb_XerD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51900">
        <property type="entry name" value="CB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5 11" id="KW-0132">Cell division</keyword>
    <keyword evidence="6 11" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="4 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 11" id="KW-0229">DNA integration</keyword>
    <keyword evidence="9 11" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="8 11 12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core-binding (CB)" evidence="14">
        <location>
            <begin position="2"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="Tyr recombinase" evidence="13">
        <location>
            <begin position="108"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="148"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="172"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="244"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="247"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="270"/>
        </location>
    </feature>
    <feature type="active site" description="O-(3'-phospho-DNA)-tyrosine intermediate" evidence="11">
        <location>
            <position position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEZ41836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="298" mass="34484" checksum="510AE9D7F8B83E30" modified="2010-01-19" version="1">MENDDVVIERFLDAMWMERGLSENTLASYRNDLTKLMMWMKEHKLVLESISADDLQRYQQWLFDQDYKQTSRARMVSAIRRVFQYLHREKIRVDDPSAMLISPKLPKRLPKDISEAQVDALLDAPNVDDPIELRDKAMLELLYATGLRVTELVSLTMENISLRQGVVRVVGKGDKERLVPMGENAVDWIEQFLAQGRPMLLGEKSSDVVFPSKRAQQMTRQTFWHRIKHYAVLAGIDADTLSPHVMRHAFATHLLNYGADLRVVQMLLGHSDLSTTQIYTHVATERLKQLHEQHHPRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z007</accession>
    <name>D0Z007_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Branched-chain amino acid transport system carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_002870</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the transport system for branched-chain amino acids.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell inner membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the branched chain amino acid transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41838">
        <property type="protein sequence ID" value="EEZ41838"/>
        <property type="gene ID" value="VDA_002870"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1114">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015658">
        <property type="term" value="F:branched-chain amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004685">
        <property type="entry name" value="Brnchd-chn_aa_trnsp_Livcs"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30588">
        <property type="entry name" value="PTHR30588"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05525">
        <property type="entry name" value="Branch_AA_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00796">
        <property type="entry name" value="livcs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="75"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="108"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="152"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="183"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="239"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="272"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="297"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="327"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="360"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="393" mass="41587" checksum="37BAB732794EE3B1" modified="2010-01-19" version="1">MFGFLVTAVGLPLIGIIAVALAGGGWKGLTRDLPPFVATLMAVLIFIIIGPAFAAPRTGLVAYEMAVKPFLGADAGQTSLTVFSVIFFAVALFFAWSRGKLIDMIGKFLTPALFAVLAILAIAVFVNPQGAIEAAQADYVTQPFTKGFLEGYNTMDTFAALMFGMLIVDVIRSKGITDEKETCTYLIYAGLIAAAGLAFVYVSLFYLGATSSTVAGGAANGGEILTAYVQALFGSTGQIILSAIVLLACLTTAIGLISACSDYFSSLTKLSYEKWAVILAVICAVVANVGLNQLITLSIPVLFALYPVAIALVALTFVRRWLPNPALAYRVVLAVSLLFSLIDVAKYLGFDMSALNVLPLYDYGMAWVLPTFIALVVTRFIGGNGAEHQTRTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z052</accession>
    <name>D0Z052_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mutator family transposase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_000816</name>
        <name evidence="8" type="ORF">VDA_002915</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">Required for the transposition of the insertion element.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the transposase mutator family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301335.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39796">
        <property type="protein sequence ID" value="EEZ39796"/>
        <property type="gene ID" value="VDA_000816"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41883">
        <property type="protein sequence ID" value="EEZ41883"/>
        <property type="gene ID" value="VDA_002915"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3328">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="792870at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001207">
        <property type="entry name" value="Transposase_mutator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33217">
        <property type="entry name" value="PTHR33217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00872">
        <property type="entry name" value="Transposase_mut"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01007">
        <property type="entry name" value="TRANSPOSASE_MUTATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0814">Transposable element</keyword>
    <keyword evidence="4 6" id="KW-0815">Transposition</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ41883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="402" mass="46552" checksum="7A12DA0EFC2BD309" modified="2010-01-19" version="1">MDKKALEAFAREAAKSIKTESDLDDFRKMLTKVTVETALNAELDEHLGYQKHQARTSSNSRNGYSGKSIITDDGEVDIEIPRDREASFEPQLIRKHQTRFQSMDDKILSLYAKGMTTREIVATFKEMYDADVSPTLISKVTDSVLEQVIEWQSRPLDEVYPIVYLDCIVIKVRQDKQVINKAVYLALGVNMEGQKELLGMWLSETEGAKFWLNVLTELQNRGVKDILIACVDGLKGFPDAINTVFPETQIQLCIVHMVRNSVKYVPWKDYRAVTADLKKIYQSATEDEALLALEQFSARWDSKYPQISRSWTTHWDNLNTLFSYPEDIRRAIYTTNAIESLNSVIRKAIKKRKLFPTDESARKVIYLAIRDASKKWTMPIRNWRQALNRFMIMFEDRLSEYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z056</accession>
    <name>D0Z056_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Probable cytosol aminopeptidase</fullName>
            <ecNumber evidence="8">3.4.11.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Leucine aminopeptidase</fullName>
            <shortName evidence="8">LAP</shortName>
            <ecNumber evidence="8">3.4.11.10</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Leucyl aminopeptidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">pepA</name>
        <name evidence="10" type="ORF">VDA_002919</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>Release of an N-terminal amino acid, Xaa-|-Yaa-, in which Xaa is preferably Leu, but may be other amino acids including Pro although not Arg or Lys, and Yaa may be Pro. Amino acid amides and methyl esters are also readily hydrolyzed, but rates on arylamides are exceedingly low.</text>
            <dbReference type="EC" id="3.4.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 8">
            <text>Release of an N-terminal amino acid, preferentially leucine, but not glutamic or aspartic acids.</text>
            <dbReference type="EC" id="3.4.11.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="8">Binds 2 manganese ions per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the peptidase M17 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.1" evidence="8"/>
    <dbReference type="EC" id="3.4.11.10" evidence="8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002919"/>
    <dbReference type="MEROPS" id="M17.003"/>
    <dbReference type="EnsemblBacteria" id="EEZ41887">
        <property type="protein sequence ID" value="EEZ41887"/>
        <property type="gene ID" value="VDA_002919"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0260">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00433">
        <property type="entry name" value="Peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00181">
        <property type="entry name" value="Cytosol_peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011356">
        <property type="entry name" value="Leucine_aapep/pepB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043472">
        <property type="entry name" value="Macro_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000819">
        <property type="entry name" value="Peptidase_M17_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023042">
        <property type="entry name" value="Peptidase_M17_leu_NH2_pept"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008283">
        <property type="entry name" value="Peptidase_M17_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11963">
        <property type="entry name" value="PTHR11963"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00883">
        <property type="entry name" value="Peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02789">
        <property type="entry name" value="Peptidase_M17_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00481">
        <property type="entry name" value="LAMNOPPTDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52949">
        <property type="entry name" value="SSF52949"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00631">
        <property type="entry name" value="CYTOSOL_AP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8 10" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 8" id="KW-0464">Manganese</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 8" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CYTOSOL_AP" evidence="9">
        <location>
            <begin position="291"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="223"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="297"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="216"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="293"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ41887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="444" mass="48106" checksum="3A292A96EEF296A7" modified="2010-01-19" version="1">MLLLHHVPNILSERVLLVGCGKERELDERQYKQIIKKTISTLNETGSMEAVCFLTELHVKGRDTYWKVRQAVETTKDSLYTFNQFKSNKPETRRPLRKLVFNVPTRRELSLGERAINHGLSISSGVKAAKDLGNMPPNVANPAYLASQARRLADDFDTVTAKIIGEQEMQTLGMTSYLAVGQGSKNEAMMSIIEYKGNPDPEAKPIVLVGKGLTFDSGGISIKPSAQMDEMKYDMCGAATVFGAMKALAKLNLPINVVGVLAGCENMPGGGAYRPGDILTTMSGQTVEVLNTDAEGRLVLCDALTYVERFEPECVVDVATLTGACVVALGHHISGLMGNHNPLAHELINASEQAGDRAWRLPLAEEYQEQIASPFADMANIGSPGAGTITAGCFLSRFTKKYNWAHLDIAGTAWKGGANKGATGRPVPLLVQFLLNRAGQELVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z063</accession>
    <name>D0Z063_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Arginine deiminase</fullName>
            <shortName evidence="3">ADI</shortName>
            <ecNumber evidence="3">3.5.3.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Arginine dihydrolase</fullName>
            <shortName evidence="3">AD</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">arcA</name>
        <name evidence="5" type="ORF">VDA_002926</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>H2O + L-arginine = L-citrulline + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:19597"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
            <dbReference type="EC" id="3.5.3.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid degradation; L-arginine degradation via ADI pathway; carbamoyl phosphate from L-arginine: step 1/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the arginine deiminase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.3.6" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301370.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="SMR" id="D0Z063"/>
    <dbReference type="STRING" id="675817.VDA_002926"/>
    <dbReference type="EnsemblBacteria" id="EEZ41894">
        <property type="protein sequence ID" value="EEZ41894"/>
        <property type="gene ID" value="VDA_002926"/>
    </dbReference>
    <dbReference type="GeneID" id="57340770"/>
    <dbReference type="eggNOG" id="COG2235">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="592329at2"/>
    <dbReference type="UniPathway" id="UPA00254">
        <property type="reaction ID" value="UER00364"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016990">
        <property type="term" value="F:arginine deiminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019547">
        <property type="term" value="P:arginine catabolic process to ornithine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018101">
        <property type="term" value="P:protein citrullination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00242">
        <property type="entry name" value="Arg_deiminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003876">
        <property type="entry name" value="Arg_deiminase"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006356">
        <property type="entry name" value="Arg_deiminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01466">
        <property type="entry name" value="ARGDEIMINASE"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01078">
        <property type="entry name" value="arcA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0056">Arginine metabolism</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Amidino-cysteine intermediate" evidence="3 4">
        <location>
            <position position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR006356-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="406" mass="45159" checksum="EA85B835B344BD82" modified="2010-01-19" version="1">MSKFYVGSEIGQLRRVLVHRPERALSLLTPSNCHELLFDDVLAVERAGEEHDVFAKVLEEQGVEVMLLHNLLAETLAVPEAKEWLLTSQISVNRFGPTFANDIRCFLADMPNDELAAILLGGLSYAELPFKSSSMMQGLHAPYDFIIEPLPNHLFTRDTSCWVYGGVSINPMAKPARQRETNHLRAIYRWHPTFAGQDFIKYFGDEEKIYDNSTIEGGDVLVIGKGAVLIGMSERTTPQGVEQLASSLFKHGQAKQVIAMELPKHRSCMHLDTVMTHMREDTFSVYPEVVRKDVKCWSLTGDESGTVKATEEDYFVTAIEKALGVGQLNLITTGGDSFEAEREQWNDANNVLTVKPGVVVGYECNTYTNEKYDKAGITVLPIPGDQLGRGRGGARCMSCPIERDGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z068</accession>
    <name>D0Z068_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Endoribonuclease L-PSP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002931</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RutC family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301381.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002931"/>
    <dbReference type="EnsemblBacteria" id="EEZ41899">
        <property type="protein sequence ID" value="EEZ41899"/>
        <property type="gene ID" value="VDA_002931"/>
    </dbReference>
    <dbReference type="GeneID" id="57340764"/>
    <dbReference type="eggNOG" id="COG0251">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1850770at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006056">
        <property type="entry name" value="RidA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019897">
        <property type="entry name" value="RidA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11803">
        <property type="entry name" value="PTHR11803"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="SSF55298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00004">
        <property type="entry name" value="TIGR00004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01094">
        <property type="entry name" value="UPF0076"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="128" mass="13748" checksum="0AB5CFF3E20DE6EB" modified="2010-01-19" version="1">MTKVLHTDNAPAAIGPYVQGVDLGNMVLTSGQIPVNPATGEVPEAIAEQARQSLDNVKAVVEASGLQVSDIVKMTVFVKDLNDFAAVNEVYGNFFDEHNAPYPARSCVEVARLPKDVKIEIEAIAVRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z069</accession>
    <name>D0Z069_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">1-acyl-sn-glycerol-3-phosphate acyltransferase</fullName>
            <ecNumber evidence="4 6">2.3.1.51</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_002932</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>a 1-acyl-sn-glycero-3-phosphate + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphate + CoA</text>
            <dbReference type="Rhea" id="RHEA:19709"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57970"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:58608"/>
            <dbReference type="EC" id="2.3.1.51"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 2/3.</text>
    </comment>
    <comment type="domain">
        <text evidence="6">The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.51" evidence="4 6"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301382.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002932"/>
    <dbReference type="EnsemblBacteria" id="EEZ41900">
        <property type="protein sequence ID" value="EEZ41900"/>
        <property type="gene ID" value="VDA_002932"/>
    </dbReference>
    <dbReference type="GeneID" id="57340762"/>
    <dbReference type="eggNOG" id="COG0204">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1756450at2"/>
    <dbReference type="UniPathway" id="UPA00557">
        <property type="reaction ID" value="UER00613"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003841">
        <property type="term" value="F:1-acylglycerol-3-phosphate O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016024">
        <property type="term" value="P:CDP-diacylglycerol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004552">
        <property type="entry name" value="AGP_acyltrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00530">
        <property type="entry name" value="AGP_acyltrn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="6" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="domain" description="PlsC" evidence="8">
        <location>
            <begin position="67"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="240" mass="26675" checksum="E7AD108A8432D53F" modified="2010-01-19" version="1">MIFLLRIIAVAIFAIVTFVFGCGYCLLSPRNPKHVYTFGRIFSKMSRVLGIKLEFRYADGADKVGPAVYIANHQNNYDLFTVSGAIMPRTVTVGKKSLVWMPLFGQLYWITGNILIDRANRSKAVGTIGQVVEKIKQNKVSVWMFPEGTRSRGRGLLPFKTGAFHAAIGANVPVVPIVCSSTEHVKLNRWDNGVVIVEVMPAVSTDGLSKEDVRKLSDECRTMMEQKLNELNAEAKARSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0F8</accession>
    <name>D0Z0F8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_003022</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003022"/>
    <dbReference type="EnsemblBacteria" id="EEZ41989">
        <property type="protein sequence ID" value="EEZ41989"/>
        <property type="gene ID" value="VDA_003022"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3137">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007433">
        <property type="entry name" value="DUF481"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04338">
        <property type="entry name" value="DUF481"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="249" mass="28223" checksum="CB7E75B098366960" modified="2010-01-19" version="1">MLLLLANTAAYAETAQTPDETNEESVPSPLTTELELGYQSLSGNSDSQSMNTRLKFIYTKQRFYNTAEFKFLLAEKDGEEDKRKGSIEVQSNMIIDDRTYVFGNANYIDDRYGPYYADFTFSSGLGYRLFRLQDFQMRAEAGPGYRHQEPNLDEIGSGDIIKRNLVDEPILRGYTTMTWKPSKTVEFSASLTGVVGNSNSTIESELNMTSSVTERIAIKISNTQKLYSWVPDGLEKRDSTTMINMLFKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0G3</accession>
    <name>D0Z0G3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribonuclease R</fullName>
            <shortName evidence="6">RNase R</shortName>
            <ecNumber evidence="6">3.1.13.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rnr</name>
        <name evidence="9" type="ORF">VDA_003027</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates.</text>
            <dbReference type="EC" id="3.1.13.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the RNR ribonuclease family. RNase R subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.13.1" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301632.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003027"/>
    <dbReference type="EnsemblBacteria" id="EEZ41994">
        <property type="protein sequence ID" value="EEZ41994"/>
        <property type="gene ID" value="VDA_003027"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0557">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1602988at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008859">
        <property type="term" value="F:exoribonuclease II activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01895">
        <property type="entry name" value="RNase_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011129">
        <property type="entry name" value="CSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040476">
        <property type="entry name" value="CSD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013223">
        <property type="entry name" value="RNase_B_OB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001900">
        <property type="entry name" value="RNase_II/R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022966">
        <property type="entry name" value="RNase_II/R_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004476">
        <property type="entry name" value="RNase_II/RNase_R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011805">
        <property type="entry name" value="RNase_R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013668">
        <property type="entry name" value="RNase_R_HTH_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17876">
        <property type="entry name" value="CSD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08461">
        <property type="entry name" value="HTH_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08206">
        <property type="entry name" value="OB_RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00773">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00357">
        <property type="entry name" value="CSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00955">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00358">
        <property type="entry name" value="3_prime_RNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02063">
        <property type="entry name" value="RNase_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01175">
        <property type="entry name" value="RIBONUCLEASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="S1 motif" evidence="8">
        <location>
            <begin position="655"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="744"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="783"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="787"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="840"/>
            <end position="861"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="861" mass="97596" checksum="1EF0961900C03B16" modified="2010-01-19" version="1">MSTGTTDLPVDPFRDREATNYENPIPSREMLLEVIRGFDTPISRDQLFAELKLEGDDQYEGLRRRLRAMERDGQLIFTRRQCYALPERLDLIKGYVMGHRDGFGFVRPEGNMSKDDDLLLPVHQMRGVIHGDYILAQVAGVDKRGRKEGRVVRVLKPTTAQIVGRFFIEDGMGYVVPDDSRIAQDIVIPQADRLGARMGNVVVVEITQRATRQYNAVGKVVEVLGENMAPGMEIEIALRTHDIPHEWPADVEKQIKDLTEEVPEEAKQGRVDLRQLPLVTIDGEDARDFDDAVFCEKKKSGGWRLWVAIADVSYYVRHDSALDKEAVKRGNSVYFPSQVIPMLPEVLSNGLCSLNPQVDRLCMVCEMTISDTGKLSGYKHYEAVMNSHARLTYTKVSKMLEGDEELRERYAPLVPHLEELYSMYKVLKEAREARGAIEFETVETQFIFNADRKIDRIVPAVRNDAHKIIEECMILANIASARFVEKAKEPALYRVHDVPGEERLTGFRDFLGELGLQLDGGFEPAPADYAKLAHQIEGREDKELIQTMLLRSMKQAVYQADNIGHFGLALKQYAHFTSPIRRYPDLTLHRAIKYLIAKQEGRNQDRWTPTGGYHYSFDDIDVLGEQCSMTERRADDATRDVADWLKCEYMQDHLGDEFDGVIANVTGFGFFVRLNELNIDGLVHVSNLANDYYQYDPIGQRLIGESSGQIYRLGDSVKVKVAAINLNDRQIDFDLVGSKRKVRGEGKTAKNRDKKQRMRKAEGLKRQSLKVYRVEDGAAVVDPAKQEQQQAEKKKDCRSTRQKLKQGAIPKFEDDKAPKGRGKGGKKKASTDTKAKAKPSTAARKKKKQRAGKAERAAKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0M5</accession>
    <name>D0Z0M5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Uroporphyrinogen decarboxylase</fullName>
            <ecNumber evidence="4">4.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_003089</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 4/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the uroporphyrinogen decarboxylase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.37" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003089"/>
    <dbReference type="EnsemblBacteria" id="EEZ42056">
        <property type="protein sequence ID" value="EEZ42056"/>
        <property type="gene ID" value="VDA_003089"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0407">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00321"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004853">
        <property type="term" value="F:uroporphyrinogen decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00717">
        <property type="entry name" value="URO-D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038071">
        <property type="entry name" value="UROD/MetE-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006361">
        <property type="entry name" value="Uroporphyrinogen_deCO2ase_HemE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000257">
        <property type="entry name" value="Uroporphyrinogen_deCOase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01208">
        <property type="entry name" value="URO-D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51726">
        <property type="entry name" value="SSF51726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01464">
        <property type="entry name" value="hemE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00907">
        <property type="entry name" value="UROD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="6 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uroporphyrinogen_deCOase" evidence="8">
        <location>
            <begin position="79"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ42056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="292" mass="32353" checksum="DC28AAED9AFA7082" modified="2010-01-19" version="1">MRRFELDAAILFSDILTIPDAMGLGLYFEAGEGPKFERPITCKADVDKIGLPDPEGELQYVMNAVRQIRKDLQGQVPLIGFSGSPWTLATYMVEGGSSKAFTKIKKMMYAEPQTLHLLLDKLADSVIEYLNAQIKAGAQAVMVFDTWGGVLTPRDYNEFSLRYMHKIVDGLIRENEGRRVPVTLFTKNGGMWLEQIAATGCDGVGLDWTIDIAEAKRRIGDKVALQGNMDPSMLYAQPERIRQEVATILEGFGDGGTGHVFNLGHGIHLDVPPENAEVFVNAVHELSKPYHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0N3</accession>
    <name>D0Z0N3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Transcription termination/antitermination protein NusG</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">nusG</name>
        <name evidence="9" type="ORF">VDA_003097</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Participates in transcription elongation, termination and antitermination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the NusG family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003097"/>
    <dbReference type="EnsemblBacteria" id="EEZ42064">
        <property type="protein sequence ID" value="EEZ42064"/>
        <property type="gene ID" value="VDA_003097"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0250">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006354">
        <property type="term" value="P:DNA-templated transcription, elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription, termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032784">
        <property type="term" value="P:regulation of DNA-templated transcription, elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031564">
        <property type="term" value="P:transcription antitermination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00948">
        <property type="entry name" value="NusG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006645">
        <property type="entry name" value="NGN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036735">
        <property type="entry name" value="NGN_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043425">
        <property type="entry name" value="NusG-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001062">
        <property type="entry name" value="Transcrpt_antiterm_NusG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015869">
        <property type="entry name" value="Transcrpt_antiterm_NusG_bac_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30265">
        <property type="entry name" value="PTHR30265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30265:SF2">
        <property type="entry name" value="PTHR30265:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00467">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02357">
        <property type="entry name" value="NusG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00338">
        <property type="entry name" value="NUSGTNSCPFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00739">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00738">
        <property type="entry name" value="NGN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82679">
        <property type="entry name" value="SSF82679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00922">
        <property type="entry name" value="nusG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01014">
        <property type="entry name" value="NUSG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 5 6" id="KW-0889">Transcription antitermination</keyword>
    <keyword evidence="3 5 6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="1 5 6" id="KW-0806">Transcription termination</keyword>
    <feature type="domain" description="NGN" evidence="7">
        <location>
            <begin position="2"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="KOW" evidence="8">
        <location>
            <begin position="116"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ42064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="170" mass="19231" checksum="3D734072D0576291" modified="2010-01-19" version="1">MQAFSGFEGRVAQSLREHIKMHGMEEYFEEVLVPTEEVVEVRAGQRRKSERKFFPGYVLVQMVMNDETWHLVRSIPRVMGFIGGTSDRPAPISDKEADAILNRLQKASESPVHKTVFEPGEVVRVTDGPFADFNGVVEEVDYDKSRVKVSVSIFGRATPVELEFGQVEKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0Q8</accession>
    <name>D0Z0Q8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Putative type II secretory pathway component EpsD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_003122</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 8">Cell outer membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the bacterial secretin family. GSP D subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003122"/>
    <dbReference type="EnsemblBacteria" id="EEZ42089">
        <property type="protein sequence ID" value="EEZ42089"/>
        <property type="gene ID" value="VDA_003122"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1450">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.120">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001775">
        <property type="entry name" value="GspD/PilQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005644">
        <property type="entry name" value="NolW-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038591">
        <property type="entry name" value="NolW-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004846">
        <property type="entry name" value="T2SS/T3SS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013356">
        <property type="entry name" value="T2SS_GspD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00263">
        <property type="entry name" value="Secretin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03958">
        <property type="entry name" value="Secretin_N"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00811">
        <property type="entry name" value="BCTERIALGSPD"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02517">
        <property type="entry name" value="type_II_gspD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Secretin_N" evidence="9">
        <location>
            <begin position="35"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="Secretin_N" evidence="9">
        <location>
            <begin position="101"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="Secretin_N" evidence="9">
        <location>
            <begin position="175"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ42089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="579" mass="62910" checksum="261BBB91146BBAE7" modified="2010-01-19" version="1">MPDGVLKVIRSKDAKTSAIPVVGSDSKTYGDEVVTRVIAVKNVSVRELSPLLRQLNDNAGAGNVVHYDPANIIMITGRAAVVNRLAEIIERVDRAGNKDVTIVSLNNASASEMVRIVESLNKSADKSVPEFLVPKVVADDRTNSVLISGDPKVRARLKTLIHQLDREMATRDDNQVIYLKYAKAEDLLETLTGISENLQAKEGGQAKSASSSKNEVSINADKGTNSLVISAPPDLMRKLKDIISQLDIRRAQVHIEAMIVEVQEGDGLNFGVQWGSEDGGIIQYGNSPVGIGSYMVAKKEAEDQTKVETRYDSDGKPYTYETKESGDYSSLAKLLGGVNGTAVAIAMGDWTALVNAVRTNRNANVLSTPSITVLDNQEAELSVGQEVPVQTGSTSSSNNDNPFTTVERKDVGIQLTVTPQINEGDSVKLDIKQVVSQVADAQGAVDIRFDKRELNTAVLVKDGSMIALGGMMQEKALESESKVPILGDIPVLGSLFRSTNNETVKTNLLIFIKPTIIRDGMTADGITQRKYNYIRAQQLYEAEKGMRLLDKDKPVLPRYGDDMDLPAEVRAFVSQLEHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0U5</accession>
    <name>D0Z0U5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Adenylate cyclase</fullName>
            <ecNumber evidence="4">4.6.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">ATP pyrophosphate-lyase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Adenylyl cyclase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">VDA_003159</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP = 3',5'-cyclic AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:15389"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58165"/>
            <dbReference type="EC" id="4.6.1.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the adenylyl cyclase class-1 family.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.1" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302036.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003159"/>
    <dbReference type="EnsemblBacteria" id="EEZ42126">
        <property type="protein sequence ID" value="EEZ42126"/>
        <property type="gene ID" value="VDA_003159"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3072">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1153472at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006171">
        <property type="term" value="P:cAMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000274">
        <property type="entry name" value="Adenylate_cyclase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024686">
        <property type="entry name" value="Adenylate_cyclase_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024685">
        <property type="entry name" value="Adenylate_cyclase_1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38760">
        <property type="entry name" value="PTHR38760"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12633">
        <property type="entry name" value="Adenyl_cycl_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01295">
        <property type="entry name" value="Adenylate_cycl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001444">
        <property type="entry name" value="Adenylate_cycl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01092">
        <property type="entry name" value="ADENYLATE_CYCLASE_1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0115">cAMP biosynthesis</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10 16" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Adenyl_cycl_N" evidence="15">
        <location>
            <begin position="21"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="848"/>
            <end position="873"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00032597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF12633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EEZ42126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="873" mass="100777" checksum="07F47490DFC167E6" modified="2010-01-19" version="1">MTRFGPLNAGSSWKSNLHNYIKTLKSRLESFNQLRIERARIAMDAQSVQVFDLLPVLLHINHPALPGYLDDEVPQGIAGFSLSHTQQQFVDDCGLTADKVVAPLNIADDLCPITGLYAMGSTASIGQSLTSDLDIWVCIRADLSSELRQILDSKCSLVSEWAMSQGVEANFFLIDENRFRHNFSEEMTGENCGSSQHLLLLDEFYRSAVCLAGLPLLWFMVPPEMEECYDQYVDYLEQQGHIRRNEWVDFGGVSRIPAEEYFGSSLWQLYKSIDSPYKSVLKAILLEAYSWEYPHTQLLSLDGKRRFFAEDRTEYCMDAYYLMLEKVTRYLERIDDHRRLDLVRRCFYLKTHEKLTRTPALGSVAWRRRVLEQLTEQWQWTPADLWALDNRRNWKVNQVKQAHNELLDALMLSYRNLIRFARRNNITSAISPEDISILARKLYAAFEVLPGKVTLLNPQISPDLHEQDLTLIQVPAGRTNTAGWYLYKQPLEPYAILGQPALEHNRYLSKLVAWAYFNGLLTESTCLHTVVRDSDMDIDKLYQLVSDIRNTFTIRRPQPSLQALSSPCEIRQLGIFINLEQDPTTELKNRSSVRFDFKNTDIFSYGPEQHCLVGSVDLVYRNSWNEVRTLNFKGESAMLDALKTILGKMHQDAIPPELVDVFCYSKHMRGLIRNLVYQLVAECIEMRLKPVEQEKRRRFKAIRIGNQMYGLFFERRGVSVQKLENSIDFYRSISANKLIGSANTVVEMGEEPHPPEIVDAYASEGLIQFFFEDCDDGFNIYILDETNRIEVYRQCGGDKDELVHGVNRFYTSAQDRFSYSANFINFNLPQFYDIVHNEKGVQVLPYKSGQQMQRRPQTGNNNTLPNIANYSPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0V2</accession>
    <name>D0Z0V2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Sensory box/GGDEF family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_003166</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302056.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003166"/>
    <dbReference type="EnsemblBacteria" id="EEZ42133">
        <property type="protein sequence ID" value="EEZ42133"/>
        <property type="gene ID" value="VDA_003166"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2202">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2984">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5001">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007487">
        <property type="entry name" value="ABC_transpt-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04392">
        <property type="entry name" value="ABC_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019959" evidence="1">
        <location>
            <begin position="20"/>
            <end position="1051"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="2">
        <location>
            <begin position="495"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="4">
        <location>
            <begin position="648"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="3">
        <location>
            <begin position="792"/>
            <end position="1047"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ42133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="1051" mass="119788" checksum="41D028DB73BE83F4" modified="2010-01-19" version="1">MVLRWFSIALFLISTSVFADSVKTQNVLVIHSYHQGLGWTDAVQSGLEDITANKNIALNVSYMDSKRYQSKAYLHELVAIYRIKLRSEKYSAIVVTDDRALWLIDQLGSEIGNTPVIIGGINNYSASKHQSIAKVAGFIELQDAGDNIQLALNVKPNLKQVFLIADDTLTGKSMWQSARNYLRQHPNPDITFTRMGQYSFKEMFDQAKWLPQDSAVIFLSYFIDGLGNYMPSDEFLSQFTANASAPVFVPYSYMLNYGALGGVVTSGYKLGLGLGELLEQVLQGKVTHYPYIRPNKNEVMFNYQALSRWGISIGNEQALVVNRPLSWFERHHKELKTLGFVVLVMGSVIILLSLMIRHLRRSEQQLQRSQALFETVFDQSFQYIGILDLHGHLVSANLALQEMLGDDGVKFDRPIWRWLCWNSDTASQLNQAFLAADTEFLLRFEAKAQSQNDGIRILDISLKAMPYQAATEPQILFEARDMTSRRQMEQKLREREVSYHLLYEQQPVILLTIDNSARIQSVNQFAADLLGYHKRDLLGHKITEFYLEGILPPHQIISHSGVESREVWRRQVQYRRADGETVWVRETVRQAQAKHQLLIVGEDITSTRELEQRLAYQANHDYLTGLYNRSYFESQLELALDEVQQQDVQHAMLYIDLDQFKVINDTAGHEAGDEALKQVALGLQNLATENTILARLGGDEFAVILRHCDEEQALALGRKILHLLDDAEFLWQNTRFNFSCSLGIRLIDKTAGSPQQVHAQADTACYVAKDEGRNRLHLYRPDDEELKRREHEMHYVNRIRRALVECRFELYAQQIAPIGRSSKNHHYEILLRMRELDGSIASPGVFIPAAERYNLAHLLDRYVIQQVLSWYQQHPEAIEKLGHCSINLSGQSIGNQEFVKFLLHQIRHSTVPANKICLEITETAAIGNMTQAISLFTQLKELGCLISLDDFGSGLSSFGYLKRMPVDVLKIDGMFVRDIDKDDMDFAMVKAINELAKKMGKQTVAEFVENKAILDKLESLGVDYAQGYYFGQPKPLAELVDDLSQEPEPMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0W9</accession>
    <name>D0Z0W9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Oligopeptidase A</fullName>
            <ecNumber evidence="8">3.4.24.70</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">VDA_003183</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>Hydrolysis of oligopeptides, with broad specificity. Gly or Ala commonly occur as P1 or P1' residues, but more distant residues are also important, as is shown by the fact that Z-Gly-Pro-Gly-|-Gly-Pro-Ala is cleaved, but not Z-(Gly)(5).</text>
            <dbReference type="EC" id="3.4.24.70"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the peptidase M3 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.70" evidence="8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302096.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003183"/>
    <dbReference type="MEROPS" id="M03.004"/>
    <dbReference type="EnsemblBacteria" id="EEZ42150">
        <property type="protein sequence ID" value="EEZ42150"/>
        <property type="gene ID" value="VDA_003183"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0339">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1935578at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06456">
        <property type="entry name" value="M3A_DCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034005">
        <property type="entry name" value="M3A_DCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024077">
        <property type="entry name" value="Neurolysin/TOP_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024080">
        <property type="entry name" value="Neurolysin/TOP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045666">
        <property type="entry name" value="OpdA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045090">
        <property type="entry name" value="Pept_M3A_M3B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001567">
        <property type="entry name" value="Pept_M3A_M3B_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11804">
        <property type="entry name" value="PTHR11804"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01432">
        <property type="entry name" value="Peptidase_M3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19310">
        <property type="entry name" value="TOP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2 9" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="TOP_N" evidence="11">
        <location>
            <begin position="27"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M3" evidence="10">
        <location>
            <begin position="223"/>
            <end position="677"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00026100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF19310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ42150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="680" mass="76637" checksum="6F462E99C34128DF" modified="2010-01-19" version="1">MSNPLLSMTDLPPFAHILPEHVKPAVEQAIADCRAQVEQVLANPQAPSWETICAPLAETDDRLSRIWSPIGHLNGVKNSPELREAYESCLPLLSDYGTWVGQHKGLYEAYKAIKGSDEFAELSQAQQKTITDALKDFELSGIGLPAAEQKRYGEISKRLSELSSNFSNNVLDATMGWTKHIVDVNELAGLPESALQAAQAAAQAKELDGYLLTLEMPSYLPMMTYCENRALRQEMYEAFVTRASDRGPNAGKWDNSEIIAEKLKLSHELARLLGFNSYSEKSLATKMAQTPEQVLSFLNNLAERAKPQGEREVAELREYAMTEFGAADLEPWDFAFYSEKLKQHRYSISDEELRPYFPEQKVVAGLFEVLNRLFGMEIKPRAGVEVWDESVTFYDIFDLSGTLRGSFYLDLYAREHKRGGAWMDECMVRRTRLDGSLQTPVAYLTCNFNKPVGDKPALFTHDEVVTLFHETGHGIHHMLTQIDVPAVSGINGVPWDAVELPSQFLENWCWEEEALAFISGHYQTGEPLPKAMLEKMLAAKNFQSAMFILRQLEFGMFDFTLYTNYDPEVGAKVLDTLFEVKERVSVVPSPEWGRFPHSFSHIFAGGYSAGYYSYLWAELLSADAFSRFEEEGIFNTQTGKDFLNCILEKGGSDEPMTLFKQFRGREPQIDALLRHSGITG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1D2</accession>
    <name>D0Z1D2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">50S ribosomal protein L33</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpmG</name>
        <name evidence="6" type="ORF">VDA_003346</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the bacterial ribosomal protein bL33 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_004728408.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003346"/>
    <dbReference type="EnsemblBacteria" id="EEZ42313">
        <property type="protein sequence ID" value="EEZ42313"/>
        <property type="gene ID" value="VDA_003346"/>
    </dbReference>
    <dbReference type="GeneID" id="50534193"/>
    <dbReference type="GeneID" id="57340209"/>
    <dbReference type="eggNOG" id="COG0267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2034291at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00294">
        <property type="entry name" value="Ribosomal_L33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038584">
        <property type="entry name" value="L33_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001705">
        <property type="entry name" value="Ribosomal_L33"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018264">
        <property type="entry name" value="Ribosomal_L33_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00471">
        <property type="entry name" value="Ribosomal_L33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="SSF57829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01023">
        <property type="entry name" value="rpmG_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00582">
        <property type="entry name" value="RIBOSOMAL_L33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ42313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="55" mass="6378" checksum="8B176702D663678A" modified="2010-01-19" version="1">MAKGIREKIRLVSSAGTGHFYTTDKNKRNMPGKFEIKKFDPVVRQHVVYKEAKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1G8</accession>
    <name>D0Z1G8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cell division protein ZapB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">zapB</name>
        <name evidence="2" type="ORF">VDA_003382</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer. The ends of the coiled-coil dimer bind to each other, forming polymers. Interacts with FtsZ.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="1">Localizes to the septum at mid-cell, in a FtsZ-like pattern.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ZapB family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302611.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003382"/>
    <dbReference type="EnsemblBacteria" id="EEZ42349">
        <property type="protein sequence ID" value="EEZ42349"/>
        <property type="gene ID" value="VDA_003382"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3074">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2065751at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000917">
        <property type="term" value="P:division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043093">
        <property type="term" value="P:FtsZ-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01196">
        <property type="entry name" value="ZapB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009252">
        <property type="entry name" value="Cell_div_ZapB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06005">
        <property type="entry name" value="ZapB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0717">Septation</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="6"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="80" mass="9244" checksum="6FF6052ABB1B94E8" modified="2010-01-19" version="1">MSLEMLEMLEAKVQSAVDTIALLQMEIEELKEKNESLAAEAQDLRSGRETLVHDNDKLREDHNAWQERVRALLGKMEHVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1K4</accession>
    <name>D0Z1K4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Acetylornithine aminotransferase</fullName>
            <shortName evidence="2">ACOAT</shortName>
            <ecNumber evidence="2">2.6.1.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">argD</name>
        <name evidence="4" type="ORF">VDA_003418</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>2-oxoglutarate + N(2)-acetyl-L-ornithine = L-glutamate + N-acetyl-L-glutamate 5-semialdehyde</text>
            <dbReference type="Rhea" id="RHEA:18049"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29123"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57805"/>
            <dbReference type="EC" id="2.6.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
        <text evidence="2">Binds 1 pyridoxal phosphate per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 4/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="2">May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.11" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302672.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003418"/>
    <dbReference type="EnsemblBacteria" id="EEZ42385">
        <property type="protein sequence ID" value="EEZ42385"/>
        <property type="gene ID" value="VDA_003418"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4992">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="572533at2"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00109"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003992">
        <property type="term" value="F:N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01107">
        <property type="entry name" value="ArgD_aminotrans_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017652">
        <property type="entry name" value="Ac/SucOrn_transaminase_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004636">
        <property type="entry name" value="AcOrn/SuccOrn_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000521">
        <property type="entry name" value="Transaminase_4ab_Lys_Orn"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03246">
        <property type="entry name" value="arg_catab_astC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00707">
        <property type="entry name" value="argD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2 4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="2" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="2">
        <location>
            <begin position="107"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="2">
        <location>
            <begin position="225"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>N(2)-acetyl-L-ornithine</name>
            <dbReference type="ChEBI" id="CHEBI:57805"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="282"/>
        </location>
        <ligand>
            <name>N(2)-acetyl-L-ornithine</name>
            <dbReference type="ChEBI" id="CHEBI:57805"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="283"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ42385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="406" mass="44035" checksum="5336AABC95A4CA58" modified="2010-01-19" version="1">MMAENKVQRNVFDQVMVPCYSPMAMIPVRGEGSLVWDQDDKEYIDFAGGIAVSCLGHCHPSLVQALTEQAQKLWHLSNVMTNEPALELAQLLVANTFADKVFFANSGAEANEAALKLARRYAVDHFSTDKDQIIAFKQGFHGRTFFTVTVGGQSSYSDGFGPKPQAVIHLPYNNLDALSQVISDKTCAVMMEPLQGEGGIISPDAEFIQGVRELCDKHQALLIFDEVQTGNGRTGSLYAYQQLGVTPDILATAKSLGGGFPIGAMLTTEAIAQSMKVGTHGSTYGGNPLACAVAKAAISEIIKPELLAGVKERESWFKKGLADINQRYPIFQDIRGHGLLLGAELAPEWHGRARDILLAAGEQRLLVLVAGPNVVRFTPSLVISKLEVEQGLARLEQAIAQLYQNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1K6</accession>
    <name>D0Z1K6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">N-succinylglutamate 5-semialdehyde dehydrogenase</fullName>
            <ecNumber evidence="4">1.2.1.71</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Succinylglutamic semialdehyde dehydrogenase</fullName>
            <shortName evidence="4">SGSD</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">astD</name>
        <name evidence="9" type="ORF">VDA_003420</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>H2O + N-succinyl-L-glutamate 5-semialdehyde + NAD(+) = 2 H(+) + N-succinyl-L-glutamate + NADH</text>
            <dbReference type="Rhea" id="RHEA:10812"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58520"/>
            <dbReference type="ChEBI" id="CHEBI:58763"/>
            <dbReference type="EC" id="1.2.1.71"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid degradation; L-arginine degradation via AST pathway; L-glutamate and succinate from L-arginine: step 4/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the aldehyde dehydrogenase family. AstD subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.71" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302676.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003420"/>
    <dbReference type="EnsemblBacteria" id="EEZ42387">
        <property type="protein sequence ID" value="EEZ42387"/>
        <property type="gene ID" value="VDA_003420"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1012">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="744602at2"/>
    <dbReference type="UniPathway" id="UPA00185">
        <property type="reaction ID" value="UER00282"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043824">
        <property type="term" value="F:succinylglutamate-semialdehyde dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019544">
        <property type="term" value="P:arginine catabolic process to glutamate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019545">
        <property type="term" value="P:arginine catabolic process to succinate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd07095">
        <property type="entry name" value="ALDH_SGSD_AstD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01174">
        <property type="entry name" value="Aldedh_AstD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017649">
        <property type="entry name" value="SuccinylGlu_semiald_DH_AstD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11699:SF197">
        <property type="entry name" value="PTHR11699:SF197"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03240">
        <property type="entry name" value="arg_catab_astD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0056">Arginine metabolism</keyword>
    <keyword evidence="3 4" id="KW-0520">NAD</keyword>
    <keyword evidence="2 4 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="8">
        <location>
            <begin position="9"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="active site" evidence="4 5">
        <location>
            <position position="243"/>
        </location>
    </feature>
    <feature type="active site" evidence="4 6">
        <location>
            <position position="279"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="220"/>
            <end position="225"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ42387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="487" mass="52700" checksum="E6B146336A5A6DDB" modified="2010-01-19" version="1">MSQWIAGQWIAGQGETHISLNPYTEQAIWQGNEATYEQVHQAIEAARVAWLTWRNRDFSERRAYVERFAQLITEHQEQLAYTIAEETGKPLWETKTEVSAMVGKAAISVRAYQERTGLSRQQQGNNTMVLRHRPLGVMAVFGPYNFPGHLPNGHIIPALLAGNTVVFKPSDLTPKTAEVTMKLWQQAGLPDGVINLVQGGRATGEALAQSPLIDGLLFTGSAQTGHLLHQQLAGQPEKMLALEMGGNNPLIVTDLCSDDINATVYTIVQSAFLSAGQRCTCARRLYLPIGDKGDALLEQLVNVTQQLHVGDPFSAEQPFMGPQISSGAADKILSAQAYLATLGAEVLLAAKRGKGAIITPAILDVTKLVTLPDEEYFGPLLQVIRYSSFEQAVELANQTRYGLSAGLISLDDGQWDYFVANIRAGIVNRNRPLTGASGSAPFGGLGASGNLRPSAYYAADYCAYPMASVEGDDVELPEQLLPGIVLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1P3</accession>
    <name>D0Z1P3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">50S ribosomal protein L30</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpmD</name>
        <name evidence="8" type="ORF">VDA_003457</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2 5">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uL30 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302823.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003457"/>
    <dbReference type="EnsemblBacteria" id="EEZ42424">
        <property type="protein sequence ID" value="EEZ42424"/>
        <property type="gene ID" value="VDA_003457"/>
    </dbReference>
    <dbReference type="GeneID" id="61231788"/>
    <dbReference type="eggNOG" id="COG1841">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2084745at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01658">
        <property type="entry name" value="Ribosomal_L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01371_B">
        <property type="entry name" value="Ribosomal_L30_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036919">
        <property type="entry name" value="L30_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005996">
        <property type="entry name" value="Ribosomal_L30_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018038">
        <property type="entry name" value="Ribosomal_L30_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016082">
        <property type="entry name" value="Ribosomal_L30_ferredoxin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15892">
        <property type="entry name" value="PTHR15892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00327">
        <property type="entry name" value="Ribosomal_L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002211">
        <property type="entry name" value="Ribosomal_L30_bac-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55129">
        <property type="entry name" value="SSF55129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01308">
        <property type="entry name" value="rpmD_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00634">
        <property type="entry name" value="RIBOSOMAL_L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal_L30" evidence="7">
        <location>
            <begin position="5"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ42424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="59" mass="6714" checksum="79044480E9C4FF95" modified="2010-01-19" version="1">MAKTIKVTQTKSSIGRLPKHKATLRGLGLRRINHTVELEDTACVRGMINKVYYMVKVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1T8</accession>
    <name>D0Z1T8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MSHA biogenesis protein MshO</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003502</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303624.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003502"/>
    <dbReference type="EnsemblBacteria" id="EEZ42469">
        <property type="protein sequence ID" value="EEZ42469"/>
        <property type="gene ID" value="VDA_003502"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4966">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1497438at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="241" mass="26465" checksum="436E52D3CFFA0828" modified="2010-01-19" version="1">MKKLQGFTLMEMVIAMVILAIIMVGIGSYIEAGVKGYSSTVDRERLQSEARFLLARMTKDIRHAAPNSLSVSDTSGSKCLSFYPIVGSAAYYDNLPNNSHSLNISTFDDAKKWNSSDKIAVGFIDPQQYEKSDINFVALSDDKDNLWSLTVSSPITTSSPANRLYLYKNKISYCLLNSTIVRMTDNKTPIVMAQNVSQFKPGVEVAGLSSNAIALIGLQFKDPSSQEVANYNHSVQVLNAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1W1</accession>
    <name>D0Z1W1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized ABC transporter auxiliary component YrbC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003525</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303694.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003525"/>
    <dbReference type="EnsemblBacteria" id="EEZ42492">
        <property type="protein sequence ID" value="EEZ42492"/>
        <property type="gene ID" value="VDA_003525"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2854">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1716096at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008869">
        <property type="entry name" value="MlaC/ttg2D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042245">
        <property type="entry name" value="Tgt2/MlaC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36573">
        <property type="entry name" value="PTHR36573"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05494">
        <property type="entry name" value="MlaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004649">
        <property type="entry name" value="MlaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019911" evidence="1">
        <location>
            <begin position="21"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="211" mass="24037" checksum="E7E6E72538B9FD3D" modified="2010-01-19" version="1">MKLFRSLLMCLLALPMLAQAATVDQTNPYTMMDKVSTTMFARLKAEQKQIRSNPEELRTIVKQELLPYINVRYAAYKVLGSNLKNTTKEQRNAFVTAFSDYLVASYAQVLTQYSDQKIEIEPAKAIPADRSIISVRVDIIDQSRPPIRLDFKLRLNKKTKEWQGFDMVAEGVSMISTKQSEWSGQLRTKGIDAVTKSLQDLAAKPIHFEDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z219</accession>
    <name>D0Z219_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 13">Tetraacyldisaccharide 4'-kinase</fullName>
            <ecNumber evidence="3 13">2.7.1.130</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12 13">Lipid A 4'-kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">lpxK</name>
        <name evidence="15" type="ORF">VDA_001868</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 13">Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 13">Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 6/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the LpxK family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.130" evidence="3 13"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298844.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001868"/>
    <dbReference type="EnsemblBacteria" id="EEZ40836">
        <property type="protein sequence ID" value="EEZ40836"/>
        <property type="gene ID" value="VDA_001868"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1663">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1382484at2"/>
    <dbReference type="UniPathway" id="UPA00359">
        <property type="reaction ID" value="UER00482"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009029">
        <property type="term" value="F:tetraacyldisaccharide 4'-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00409">
        <property type="entry name" value="LpxK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003758">
        <property type="entry name" value="LpxK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42724">
        <property type="entry name" value="PTHR42724"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02606">
        <property type="entry name" value="LpxK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00682">
        <property type="entry name" value="lpxK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 13 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 13" id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword evidence="5 13" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="11 13" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 13 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="68"/>
            <end position="75"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00029757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEZ40836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="344" mass="38014" checksum="9356ECB758705212" modified="2010-01-19" version="1">MANLIEKLWFQHPPKGGMLFLYGVTWPIFFPLSKLFGYIAKKRREEYRSGKKQAYRAPVPVVVVGNITAGGNGKTPVVVWLVEQLQARGYKPGVVSRGYGGKAPYYPYLVNSDTPASIVGDEPVLIQRRTQAPVAVAPKRAEAVKLLIEQGVDIIITDDGLQHYALERDLELVVIDGQRRFGNEQLIPLGPLREPCLRLNEVDFLICNGGKPQANEAAMSLKPAPLINMKTGLRCDVSQLSDVVAMAGIGHPPRFFNTLSALGVTPIKCQPFADHQAMVEDELVQLAQHGQHLVMTEKDAVKCHGFARDNWWYLPVDAEIDSEHATAIINQIIEVKEKYGSPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z228</accession>
    <name>D0Z228_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Chromosome partition protein MukB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_001877</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001877"/>
    <dbReference type="EnsemblBacteria" id="EEZ40845">
        <property type="protein sequence ID" value="EEZ40845"/>
        <property type="gene ID" value="VDA_001877"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3096">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009295">
        <property type="term" value="C:nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030261">
        <property type="term" value="P:chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3500">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032520">
        <property type="entry name" value="MukB_hinge"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042501">
        <property type="entry name" value="MukB_hinge_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007406">
        <property type="entry name" value="MukB_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04310">
        <property type="entry name" value="MukB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16330">
        <property type="entry name" value="MukB_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MukB" evidence="5">
        <location>
            <begin position="1"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="MukB_hinge" evidence="6">
        <location>
            <begin position="547"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="744"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="210"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="409"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="838"/>
            <end position="997"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="747"/>
            <end position="766"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="1388" mass="158261" checksum="F631B82D3197D173" modified="2010-01-19" version="1">MIFAVKLQQVAGRDKKVDIKPFLIQGLPSHIKPTEVLIETVSENQARVRQINEVKDKVAEFEGVQFKTFNSVTDYHAQMFELGVLPKKLRNSQDRSKFYRLIEASLYGGISSAITRSLRDYLLPHNSGVKKAFQDMEAALRENRMTLEAIKITQSDRDLFKHLITEATNYVAADYMRHANERQKKLETTLNLRREMMGSRQTLIDQQTTLNNMSSELGELSDNEQALEQDYQAASDHLQLVQTAVRQQEKIERYREDLEELNERLEEQVMVVEEAAEQLAMAEEQAQLTEEEVDSLKTQLADYQQALDMQQTRALQYQQAIQALEKARDLSGDHQLLPDQAPPYLQQLTQEQDKQTTALLALKHKLDMSSAAAQQFDKGLAIVTTIAGAVERTNAGVKARELLAKARELRSVVERGEQLKSQYRDLERSVRNQQQATEQAQAYQKKFMVVLDGEMALAQEQERHEATLKSLEQDQAALVEQRNELRHQEQQLSAKITELEAKAPAWIAASDALERLAEQSEAELDSSQAVMEAMQKTLDSERTASSNRDQLAARKQQLDNDIERLAQPGGSDDSRLRALADTLGGTMLSEIYDDITIDDAPYFSAMYGPARHAIVVPDLQGIKDKLIALDDCPDDLYIIEGDADAFDDSGFDVDELEDAVCVHLNDRQLRYSRFPKVPLFGRAAREQRLETLREERDQVVEDHAKASFDSQKLQRLYQSFNSFVATHMAVAFLPDPEVELKSAREQRNQATRQLADSQAQEQQQRSQLAAAREGLALLGKLSPVANLLEDDTIKPRFAEVEQQLSQMDEAFIYLERHGKSLSELENLVSALDADPEQFDALQASYAQADQKLQDLKALIFAIADLAERRHYFSYADSVDLLNKSSELNEQLKLKLAAAEKERNRNRESLKQTRSQMNQYNQLLASLKSSHQAKLETVQEFERELHELGVRADVEAEERARIRRDELNERLHSSRNRRSQLEKSITSIELEMKSLAKRLRKVGKDYQDVRKLVVQAKAGWCSVLRLARESDVQRRLHRREMAYMSADELRSLSDKALGALRLAVSDNEELRDALRASEDVSRPERKVLFYIAVYQHLRERIRHDIIRTDDPVEAIEEMEVELARLTDELTAREQRLAISSDSVANIIRKTIQREQNRIRMLNQGLQNIYFGQVNGVRLNVKVRETHEALLAGLCEQKDQHNDLFGNQRLSFSEAMAKLFQRLNPHIDTGQRSPQTLGEELLDYRNYLELSIEVNRGTDGWLQAESGALSTGEAIGTGQAILLMVVQSWEEESRRLRGKDIIPCRLLFLDEAARLDGKSIATLFELCERLDMQLLIAAPENISPEKGTTYKLVRKIFKDREHVHVVGLRGFGNEPKSQDKVQTLLDLDPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z249</accession>
    <name>D0Z249_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Phosphate transport system permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">VDA_001785</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell inner membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298696.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001785"/>
    <dbReference type="EnsemblBacteria" id="EEZ40753">
        <property type="protein sequence ID" value="EEZ40753"/>
        <property type="gene ID" value="VDA_001785"/>
    </dbReference>
    <dbReference type="GeneID" id="57342109"/>
    <dbReference type="eggNOG" id="COG0573">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1325025at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:inorganic phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011864">
        <property type="entry name" value="Phosphate_PstC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02138">
        <property type="entry name" value="phosphate_pstC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="28"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="82"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="127"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="162"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="219"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="276"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="86"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ40753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="304" mass="32106" checksum="ADC86742B13F220E" modified="2010-01-19" version="1">MTIANNIENTATTMTVLKPKKSVDWRELFFKNLFLLSAAIGILSLVTIGYFIFREGFAAFAHSGVTGIVFGQDWLPPALYGIAPMIVASLASTFGAVLIGVPIALLTAVFIAEVAPKPVANIVRPMIELLAGIPSVVYGFFGLVIIVPMIQDLFNVPAGNSILAGIIVLAIMILPTVIAVSETSIRAVPRTYKEGSLALGASHMFTIFRLLIPAARSGIMTGVILGIARALGETMAIIMVMGNSPAMPRGVLDSARTLTANIAIEMSYATGIHASALYATGIVLLVFIMILNASLLYLNAKGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z258</accession>
    <name>D0Z258_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Maltose/maltodextrin ABC transporter substrate binding periplasmic protein MalE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001794</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001794"/>
    <dbReference type="EnsemblBacteria" id="EEZ40762">
        <property type="protein sequence ID" value="EEZ40762"/>
        <property type="gene ID" value="VDA_001794"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2182">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1303718at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019332" evidence="1">
        <location>
            <begin position="21"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="391" mass="44304" checksum="436D6C6422F6B581" modified="2010-01-19" version="1">MVVFRCLILLLMLIPCIANARITLWHSHQSTAYIDGLVSRFEKETGIQVSVVQFDPQKIKAELLLGAQYGGLPDLILVPSDFLGLYKQMKLSPVPKGWIHTDFEPAVGETARVNGKYRGVPIIQGNHLLLYYNKSMVKTPITSWSELLQQKKDFVSKQIMPIGWNYNDMYFFMPFLLASDGWPIKNDKISLDSLGMVNALKYYHLLAADGIIDGHCGYHCAQLGFIQGKSAYAINGDWAYDDIKKEMGDNVGLAMLPSLNGHKMYGLKSTFVLAMPEFDQRSVLVQNQLKRFIEFVQRKANQKWVYDKYHLLPVSNSLFLQLKKTAIGDNKIILEQLSLAKVMPSNVLMAIVWQAMGKGFYRFADGESAENTADYMQRVASGQLQRLEKQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z294</accession>
    <name>D0Z294_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000545</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000545"/>
    <dbReference type="EnsemblBacteria" id="EEZ39525">
        <property type="protein sequence ID" value="EEZ39525"/>
        <property type="gene ID" value="VDA_000545"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0431">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="69" mass="7017" checksum="6D2C256B15027BE9" modified="2010-01-19" version="1">MLLLATSPGPGGAANVLAGAVGSAPYFAGDVKASVSLPSFYDNFDMATGKVTNAEIDTKLKEAVEELVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z295</accession>
    <name>D0Z295_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">2-enoate reductase (Two distinct NAD(FAD)-dependent dehydrogenase domains)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_000546</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304684.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000546"/>
    <dbReference type="EnsemblBacteria" id="EEZ39526">
        <property type="protein sequence ID" value="EEZ39526"/>
        <property type="gene ID" value="VDA_000546"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0446">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1902">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1308229at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxidored_FMN" evidence="3">
        <location>
            <begin position="8"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_2" evidence="4">
        <location>
            <begin position="406"/>
            <end position="658"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="673" mass="73994" checksum="293C0E35E9BC87E8" modified="2010-01-19" version="1">MKQEHQILFTPLKIGTLTLKNRYSMAPMGTLGCVDSDGAYNARGVEYYVARAKGGVGLIITGVQMVENELEQFPMPSLPCPSYNPTAYIRSARELTERVHSYGCKIFAQLTAGWGRSCIPGFTPNDKCVAPSKAANRFDPTLEHRELATQEVKHFIAKFAESAAIAQKAGYDGVEIHAVHEGYLLDQFSLSFFNQRTDEYGGSFENRYRFAVEIVKAIKSVCGERFPVSLRYSVKSNMKGYGQGILPEEDAVEVGRDLEEGLRAAKYLQDAGYDALNVDAGTYDSWYWNHPANYFKPGMYQPYCKAVSEVVDIPVLMAGRMEDPDLAAKAVQEGVADGISMGRPLLADPDVVNKIRSGKFEQVRPCLSCHQGCLGRMAEVGNISCAVNPACGREEEYKLTPCLIKKKVMIIGGGVAGMEAARVSALRGHEVHLFEATSYLGGNVIPGSQPPFKHDDKLLIRWFEGELQRQGVYVHLNTKVTQDIIQECNADAVIFATGSKPEVPAWLSGADQSHVSVAEDILMNPELITGQSVCVIGGGLVGSELALWLAQKNKDVTLIEADNDIIGGPHGTCFANYQMLKELLVKHKVDVKLSTKLRTITETGIEIEDQDSNISSIDYPHVVLALGYKAESSMYDQLANQLEVDEIYNIGDSQQARTIMAAIWEGYEVARQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2C9</accession>
    <name>D0Z2C9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4123 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000580</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304762.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000580"/>
    <dbReference type="EnsemblBacteria" id="EEZ39560">
        <property type="protein sequence ID" value="EEZ39560"/>
        <property type="gene ID" value="VDA_000580"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4104">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1424176at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025391">
        <property type="entry name" value="DUF4123"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13503">
        <property type="entry name" value="DUF4123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4123" evidence="1">
        <location>
            <begin position="23"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="283" mass="32817" checksum="A2DF58125350A5DF" modified="2010-01-19" version="1">MSFPLNLPLPLPHFHDSNDSLNYLVVDGSQIEQLEPLLQQQDLQPQRICPTHLLPLAEVSPYIMPLTPEAMAWFVQYNQANIGYVISSEFTIDELIDAFCDYYQVLSAYGSTVFFKLGQPEAIYILLSDKTCLLWQWLTQAWLPTREGWEHVRRDQAFEAKETRLPYRLSDVQWALLGEISRRNCIEMVHQHLLHFFPAVLEQHAAPLLWIKGWVEHANTLQFETDVDVLHFFNILALLGEEIIHSDRYLHIRQLLETPSEQTPSMRVAMADKLAHKEAVDAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2E1</accession>
    <name>D0Z2E1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hypothetical rhodanese-related sulfurtransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000592</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304808.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000592"/>
    <dbReference type="EnsemblBacteria" id="EEZ39572">
        <property type="protein sequence ID" value="EEZ39572"/>
        <property type="gene ID" value="VDA_000592"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2897">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="920668at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016783">
        <property type="term" value="F:sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045078">
        <property type="entry name" value="TST/MPST-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11364">
        <property type="entry name" value="PTHR11364"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Rhodanese" evidence="2">
        <location>
            <begin position="22"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodanese" evidence="2">
        <location>
            <begin position="171"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="284" mass="31578" checksum="FC863CD87F954F92" modified="2010-01-19" version="1">MVKRHPNSSSLVTVEWLKQHITDQNLVVLDASWFMPNTGRNGEQEWLQQRIPGARFFDFDQKIAAPNTEFPHMLPTVEQFAQEVGKLGINNHSHIVVYDSHGIFSSPRVWWMFKVMGHDSVSVLDGGLPAWIEAGYELETDAPQPVVEKIFNAQYQNNWVIDADNLYAKLNNSNVSVIDARPADRFYALVAEPRAGVRSGHMPNAKSLPFPELLNCGRMLPASELSARFSALVAADQQLIFSCGSGVTACILALAADLAGYENLTVYDGSWSEWGAVEKYPVVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2F1</accession>
    <name>D0Z2F1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF1722 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000602</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304839.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000602"/>
    <dbReference type="EnsemblBacteria" id="EEZ39582">
        <property type="protein sequence ID" value="EEZ39582"/>
        <property type="gene ID" value="VDA_000602"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1683">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3272">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1757306at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007553">
        <property type="entry name" value="2-thiour_desulf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013560">
        <property type="entry name" value="DUF1722"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017087">
        <property type="entry name" value="UCP037004"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04463">
        <property type="entry name" value="2-thiour_desulf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08349">
        <property type="entry name" value="DUF1722"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037004">
        <property type="entry name" value="UCP037004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1722" evidence="1">
        <location>
            <begin position="189"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="315" mass="36336" checksum="235C067CE68C429C" modified="2010-01-19" version="1">MDIPVGISACVLGDKVRFDGGHKRSRFAAEELNSYVKFVPVCPEVGIGMPVPRQTIRLLQYEEQIRLVATKDASMDFTDQMTEFAQAQTERLQHLCGYIVCAKSPTCGMERVKLYIENGNTVPGGTAGIFTQILMENMPWLPVEEDGRLNDPYLKENFIFRVYALHDLYQAIKGGITAKAIIKFHSRYKLCLMAHSQPAYQELGRFVAEVSQWDDLDAFFVEYRQRFMDAIKHIASRKNNTNVLLHIQGYFKRELDKEQKEELRELIMRYRCGDLPLIAPLTLINHHLSLYPDEYLASQAYLNPYPENLRLRYAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2G7</accession>
    <name>D0Z2G7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_000618</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304882.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000618"/>
    <dbReference type="EnsemblBacteria" id="EEZ39598">
        <property type="protein sequence ID" value="EEZ39598"/>
        <property type="gene ID" value="VDA_000618"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="817710at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="4"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="125"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="125"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ39598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="219" mass="24676" checksum="70367ACED6E279DA" modified="2010-01-19" version="1">MNQTLLLVEDDRNLADGLLESLKQAGYNCLYADCATKVAGLWDQAEIVILDRQLPEGDSLDFLKDWLKIKTLPVIMLTAMVSITDKVVGLDSGASDYLTKPFAVEELLARIRVHLRSNGADAEPSNIITAGQIEINLDSREVRHGDEFITLTRTEFELLVFLAKNAGRVFTRDELLDQVWGYNHYPTTRTVDTHILQLRQKLVGIEIETLRGVGYRMKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2G9</accession>
    <name>D0Z2G9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NnrS protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000620"/>
    <dbReference type="EnsemblBacteria" id="EEZ39600">
        <property type="protein sequence ID" value="EEZ39600"/>
        <property type="gene ID" value="VDA_000620"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3213">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010266">
        <property type="entry name" value="NnrS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05940">
        <property type="entry name" value="NnrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="180"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="216"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="240"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="272"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="301"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="335"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="365"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="400" mass="45133" checksum="83D79FB9E3C35763" modified="2010-01-19" version="1">MMQILDNEKEQKIIPIFRLAFRPFFLSAALFSAVAMVVWAMFWSGSSHVTGLMYGHPIWWHAHEMMIGFTGAIIIGFLLTAVQTWTGVPGIRSTKLAIVFTLWLIARIGLLFGQPSYVWMFIDLSWIPLAAYFLLKPILLRRQWNNLFFAPLLLLLTALNVQLHLIAMGLVENSLRQTSFIALVVIAIIVLVVGGRVIPFFTWRGTQTEQITRVKWIEYAALIPAWLLLVATFLPLPSNYNWIVANLLMVTAVTNMIRFVRWRTLSTLKVPLLWSLHLAYLCMILGLFAIGLSMVSHVVSYSIALHLMTVGGIGGMILSMMARVSLGHTGRSLQVGYWVQIAFVCLLLSTLVRSVLIWVYPSLTINGYVFSAILWAIAFSIFTIVYYPILTKPRVDGRPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2N7</accession>
    <name>D0Z2N7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Molybdenum transport system permease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">VDA_000688</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell inner membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305059.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000688"/>
    <dbReference type="EnsemblBacteria" id="EEZ39668">
        <property type="protein sequence ID" value="EEZ39668"/>
        <property type="gene ID" value="VDA_000688"/>
    </dbReference>
    <dbReference type="GeneID" id="57343033"/>
    <dbReference type="eggNOG" id="COG4149">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1915735at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015098">
        <property type="term" value="F:molybdate ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011867">
        <property type="entry name" value="ModB_ABC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02141">
        <property type="entry name" value="modB_ABC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 9" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="89"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="135"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="197"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="10"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ39668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="229" mass="24990" checksum="F376D66F22AC17F2" modified="2010-01-19" version="1">MLTDYELTALLLSLKIAGVAIVFSLPMGIFLAWLLARKQFIGKSILDGIIHLPLVLPPVVIGYLLLISMGRQGFLGKYLYEWFGFTFSFSWRGAALAVAVVSFPLMVRSIRLAIEGVDQKLEQAARTLGATPLKVFFTITLPLTIPGILTGALLAFARALGEFGATITFVSNIPGQTQTIPLAMYSFIETPGAEEQAGRLCVIAIVIALSSLFASEWLTRLARRRLEAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2N9</accession>
    <name>D0Z2N9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_000690</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000690"/>
    <dbReference type="EnsemblBacteria" id="EEZ39670">
        <property type="protein sequence ID" value="EEZ39670"/>
        <property type="gene ID" value="VDA_000690"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="104"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="139"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="206"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="244"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="270"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="293"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="327"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="359"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="206"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="388" mass="41337" checksum="27C765CB24F66147" modified="2010-01-19" version="1">MTQTTTLDCRKSNGIFVPVAGLTIFAVASGYLMSLVPLSLASFKIDSSYASWLASSYYVGLLIGSMMIEPIIARIGHRISFIVFLSLLALPVVALPMFPNKDLWLFARLIAGMAVAGIFVVVESWLLIGDSAKERARRLGIYMTSLYGGTTIGQLAVGIFGTQGFGPFSVILGLLFAAILPPLFVRQGQPSCTEHKPLTLKQISRLSKAAIIGCITSGVVMGTIYGLMPLALKQSQLNTEQVGVLMAAIILGGMVIQPIVGQLSTRMSKTVLLALASLLGVFAMGITHLSSDFYILITALALLGMSSFALYPIAITLACDKLESSQIVAATQVMLFSYSVGSALGPIGANQFMAQPNGLMDFFFIVLLATAIYMLLASVRRKPQVLAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2P0</accession>
    <name>D0Z2P0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Dca</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_000691</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305068.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000691"/>
    <dbReference type="EnsemblBacteria" id="EEZ39671">
        <property type="protein sequence ID" value="EEZ39671"/>
        <property type="gene ID" value="VDA_000691"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2194">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1067869at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008484">
        <property type="term" value="F:sulfuric ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016772">
        <property type="term" value="F:transferase activity, transferring phosphorus-containing groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040423">
        <property type="entry name" value="PEA_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30443">
        <property type="entry name" value="PTHR30443"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="27"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="91"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="126"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="7">
        <location>
            <begin position="179"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ39671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="485" mass="55323" checksum="6D91821E1F17BF7D" modified="2010-01-19" version="1">MKYVVPLLLIIISYLLALGLDCNEYSILFSVITLFLSLYLLSANNIVKYGVVLPLFFLPIFYFSSGMQYGHPNLGVIASVMETNNQEMFEFLGDIPVINLILNLLLFVLFIFYLVKIKTEPGKLKIVLGLVVLIFSPIYAFYRHIYISGGHYIKEHRSLLASETQAPNWQILSVQPKYRNYVVIIGESMRKDYLSAYGYPIDTTPFLRQTKGLLVDGYISTAPNTAISLPRTLAISDGLHIQPADNFITLANKAGFETVWISNQGFLGKYDTAISSIAVRSDKKFFLKKGGFNSSNHYDSELLPIFTEQLAQKSEKPRLFVLHLMGSHPKFCDRVKQDIYHLKDKQLSCYLSSYHETDHLIAQVVNDLKATQQSFSLVYFSDHGLNDHIKGSGSKLTHGNQFRSNYEVPFVRISSDDKRHHVLKKTISAYYFLPFFSRWIGVETRQLKPFSWKQAGKNVRVFNWSKMIPIDQLKADPADIVSQKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2V9</accession>
    <name>D0Z2V9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000760</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39740">
        <property type="protein sequence ID" value="EEZ39740"/>
        <property type="gene ID" value="VDA_000760"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031N6U">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1882222at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="226" mass="26488" checksum="6A14578C474D3FA9" modified="2010-01-19" version="1">MLTYLRFLIISIYLLFVLPAMAYDSLEMMKSHPAILDGNHIQLPLNEYSALSILAQWHVSSSELPSEQIEMITTQYLSKDLWGNDINRNLIRDDYEKILLSSYQRPEYVVMGLLASKRWDRILELINDQTISTAESLKLMKDMIAINRCYFQLQQIDQHLRSPILDYFNTPERLQVKEQAEIKLLKNIGNRQHHLVNHNNPCDFFGTMAEKIMKEGEISYAKIKHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z330</accession>
    <name>D0Z330_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Anaerobic dimethyl sulfoxide reductase chain C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000831</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305470.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000831"/>
    <dbReference type="EnsemblBacteria" id="EEZ39811">
        <property type="protein sequence ID" value="EEZ39811"/>
        <property type="gene ID" value="VDA_000831"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3302">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="909963at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019645">
        <property type="term" value="P:anaerobic electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007059">
        <property type="entry name" value="DmsC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38095">
        <property type="entry name" value="PTHR38095"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04976">
        <property type="entry name" value="DmsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="182"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="212"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="247"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="274" mass="30938" checksum="27AEC8D31E44FC6C" modified="2010-01-19" version="1">MHELPLVFFTVLAQTVAASFLLLQALRFSPFNSYTMAKEKHKKIKIYLILLVLLGVSGSAALTHLGSPLRAPNVLFGLAHLSAMSLEIITVSIFGSLIFSLIILTALNTSNYLSKIINIFTTLFAILQLIAIANVYYLKTVYLWNTLWTWTNLIYSGFIPGSLLIALLINKSSKENSFSFKNLWCTILFISISLNIWYIFDLHAKLSTIGLTLPALIEWLLIIKNILIIISFIWCIRIDTKLNIRTYIIIVSLLITAELFGRIAFYELSLINSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3D0</accession>
    <name>D0Z3D0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000931</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39911">
        <property type="protein sequence ID" value="EEZ39911"/>
        <property type="gene ID" value="VDA_000931"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="41" mass="4898" checksum="4D75C6527B870B6F" modified="2010-01-19" version="1">MKYKDKHYTVEVHVFKTIVAEIVKKREFKLQGMQAKDMELG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3F0</accession>
    <name>D0Z3F0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">AraC-type DNA-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_000951</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305811.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000951"/>
    <dbReference type="EnsemblBacteria" id="EEZ39931">
        <property type="protein sequence ID" value="EEZ39931"/>
        <property type="gene ID" value="VDA_000951"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1622875at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032687">
        <property type="entry name" value="AraC-type_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020449">
        <property type="entry name" value="Tscrpt_reg_HTH_AraC-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12625">
        <property type="entry name" value="Arabinose_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00032">
        <property type="entry name" value="HTHARAC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="4">
        <location>
            <begin position="233"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="336" mass="39031" checksum="A465067CD559EF30" modified="2010-01-19" version="1">MIDTAFIRTLFFQPILNGLEKRYQLSPQHWDIPAKLLQEPMSLTPFLDMTAWLESAIEMTGDPNYLAKIADLVRFEQMGMLGEWFLSSPDLALAFRRINYGSSCLQSGATFHGEQSAKVIKWTYGNHYLMGQQRLLDSLRVAIMFTNVIRNYMGTDYHPIHVEISGKPERVVDYQDFFGCNITWNAPMTRVWIDIAILETGNECVFNVTKPMLLSNLQLDDLLNMPQPQDFAKVMYEMVNYNRYYDRPSIHFVAEKLQLSTQQLSRRLHNYGLNFTSITSYVLCNVAIKYMLEGMDIKKIASLLGYQNVQSFSKAFQRYRGVTPTQYQQRLLERAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3I6</accession>
    <name>D0Z3I6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000987</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305916.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39967">
        <property type="protein sequence ID" value="EEZ39967"/>
        <property type="gene ID" value="VDA_000987"/>
    </dbReference>
    <dbReference type="GeneID" id="57342543"/>
    <dbReference type="OrthoDB" id="1967820at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.645.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029014">
        <property type="entry name" value="NiFe-Hase_large"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56762">
        <property type="entry name" value="SSF56762"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="313" mass="35446" checksum="515F9ACB4E6D2E55" modified="2010-01-19" version="1">MNALLGRCDITLLTNRQEIEAAEIHYVRPEIEHALIGLEPQNAIDVLGHLPNACRISHQLAASYVLGCSTGTLLRQVNHEWINTHAMQLFLMLNKLGWKQYADSTTSALIAGQWDISEQLFGMSAELTVELIANHGVIAWLESTDMSKPYPKLLSWALRYGWQMDYQILKHSDLYQRHASTLSISEKMQDNVLFLLILSRVYELALLLSDHRLSGQWQFIKPTVEAGGVRVNAPHGELYHQAVVGWDNKIVEYQIITPTDRLCEPDGLFDYIFQHCELPENDPTVGLDLLVGALDPCVNFQYSLQDVQHTLNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3K8</accession>
    <name>D0Z3K8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ABC-type sugar transport system component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001009</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305975.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001009"/>
    <dbReference type="EnsemblBacteria" id="EEZ39989">
        <property type="protein sequence ID" value="EEZ39989"/>
        <property type="gene ID" value="VDA_001009"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1653">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1746871at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01547">
        <property type="entry name" value="SBP_bac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003020048" evidence="1">
        <location>
            <begin position="23"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="417" mass="45951" checksum="3A133DBD9258FC78" modified="2010-01-19" version="1">MNKKYLVATLLSGLVSSHVSLAGDIEVLHWWTSGGEAKSAQVLQQMMELQGHHWHNFAVAGGGGESAMTILKTRAVSGNPPTAAQLKGHDLQEWGKLGFLTSLDRIAQEQQWDKVLPPVIANIMKYDGHYVAAPVNVHRVNWLWANPKVFKAAGATIPTSLDDFFVQAKKIKQAGFVPLAHGGQPWQDVTLFENLALAVLGSTNYKRAFVTLDPKVLNGAQMVEVFRQFKRMREVIDPRFEGQSWNKATAMVIEGKAAMQIMGDWAKGEFVQANLKPGKDYICVPAPGTDQQFAYNIDSFVFFKLNGSVEDEKAQQDLAQTIMSPAFQSLFNLTKGSIPVRLDIDMSEFDQCALESMKDLKATSKTKHFVPSISQGLATTSYVQSAISDVVSEFFHDPNAKPQQAAKQLARAIRAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3M5</accession>
    <name>D0Z3M5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001026</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306017.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40006">
        <property type="protein sequence ID" value="EEZ40006"/>
        <property type="gene ID" value="VDA_001026"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031VES">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1372306at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="225"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="251" mass="29383" checksum="7913C289F4CF7A44" modified="2010-01-19" version="1">MTNYDLYLQTVDRLNDKLTDLFKFVYWQPTDNELTIDPLFVDEAGCPIQKLKVSVCRAQNIHMTSDFFKAYWLRGLARIAPLRQAVFNRHLYYWLTQSVQQFPFHLLSSSLLTNLSDDETYPFPSLIRRENSHLPCWVLARQNDEYLISIIESRTGQLYTASWVKDPDLIEDSKWFEAQVIDSVLDSSSKIEVIYQELIEEFKEQRLEDDVDLQDILHAPSLKKVSSLASVGLVFVIVIAFFIFFKYQLGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3P6</accession>
    <name>D0Z3P6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein YgiW</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001047</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306076.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001047"/>
    <dbReference type="EnsemblBacteria" id="EEZ40027">
        <property type="protein sequence ID" value="EEZ40027"/>
        <property type="gene ID" value="VDA_001047"/>
    </dbReference>
    <dbReference type="GeneID" id="57343482"/>
    <dbReference type="eggNOG" id="COG3111">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1644884at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036700">
        <property type="entry name" value="BOBF_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005220">
        <property type="entry name" value="BOF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04076">
        <property type="entry name" value="BOF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101756">
        <property type="entry name" value="SSF101756"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019973" evidence="1">
        <location>
            <begin position="20"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="BOF" evidence="2">
        <location>
            <begin position="21"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="123" mass="13067" checksum="F97196557FB1C28E" modified="2010-01-19" version="1">MKKIILASALLLASGATFAANQAVPAQGGFAGPVAANIIKTVDGALQANDDAQVELTGHIVNSLGDEDYTFKDNTGQIVIEIDHHKWNGINVTPETNIVITGEVDKDWSTRIIDVNTVRLATK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z428</accession>
    <name>D0Z428_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000284</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39266">
        <property type="protein sequence ID" value="EEZ39266"/>
        <property type="gene ID" value="VDA_000284"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG50323EC">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027385">
        <property type="entry name" value="OMP_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13505">
        <property type="entry name" value="OMP_b-brl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018828" evidence="1">
        <location>
            <begin position="25"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="OMP_b-brl" evidence="2">
        <location>
            <begin position="14"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="201" mass="21727" checksum="FE878E9F9C18FDAA" modified="2010-01-19" version="1">MKSMKGLLIVAGVLSSLVCGSAMAKAGPYIGVNIGSGGMDTPDLEVNQTSSYELRGLAGGIDAGYLWQTQQVEYGVELGFDTYAKNKYRIGDFFRMDYKGYNLDLLGVAKYNFSSQWNVFGKAGLAYVNQKLTVDGLGLIGKNKNEIKPKVALGFGYDFTPELGMNAEYSHVFAGDANSLKSDGTKVASVDMLTLGVQYRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z475</accession>
    <name>D0Z475_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Beta-mannosidase</fullName>
            <ecNumber evidence="5">3.2.1.25</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_000331</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 2 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.25" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304066.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000331"/>
    <dbReference type="EnsemblBacteria" id="EEZ39313">
        <property type="protein sequence ID" value="EEZ39313"/>
        <property type="gene ID" value="VDA_000331"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3250">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="245411at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004567">
        <property type="term" value="F:beta-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036156">
        <property type="entry name" value="Beta-gal/glucu_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006102">
        <property type="entry name" value="Glyco_hydro_2_Ig-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00703">
        <property type="entry name" value="Glyco_hydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49303">
        <property type="entry name" value="SSF49303"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro_2" evidence="4">
        <location>
            <begin position="193"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="834" mass="96437" checksum="C3E873CFC4887076" modified="2010-01-19" version="1">MATLLLDGQWQLTSPQHSHIAIPCTLPGDVHSALLAAELIVDPYFAENESLVQWVGESDWLLTREFEVSQEMLDHYAVDLTLSFVDTVADIQINQHSVLHCSNQFQTYHKEVKSTLKLGINHISILLKRSDIEAKVRAEKLPFPIPWAEGNNQIPHMNTLRKTQCHAGWDWGICLLVSGVYQSITLEPLNNTRLVNVRTTQNWLNSEHCQLELAITYQALAAFEQQQLTIDFNQQVHTIALAIDNQDIEKNHTLYYTIDVHQPKRWWPAGYGEQPLYPLEITLNEQSITKQIGFRQLELDTSLDDIGSKMQFVVNGQTITAKGANWIPLDAMPSQQTPERYRQLLQNAVDANMNMIRVWGGGTYEQDCFYQICDELGLLVWQDLMFACALYPSTVEFIQEVEQEVIQQIDRLADHPCLALWCGDNEVIGAINWYPESRQHREKYVVNYDRLNRVLAQIVAKHDPSRRFWASSPCNGELDFGDAWHDDNCGDMHFWDVWHSGKSLDAYYQVKPRFCSEFGYQSWPSLPTVKTFADYDEWNVTSPTFESHQKNKRGNSIITEMFTRYFRFPSNFANMLYLSQVQQALAIKTASEYWRAHKNHCRGILYWQLNDCWPVSSWSSIEYTGRWKQLHYHAKRFFAPQLVTFIQQDNGLLTLSAVNDEHKAVNYQGQVLQLSWQGDILQTWPINGELTSDSSDIIWQHFMNTSNINEKDHFYHVEITIECYSGSNNGQTSKIENDYFPTVFKQAKLQPGKIHAQVIEDELGIIIELDCEEPCLFVHLEVDDHLSRFSDSSFTLLPSTCSGYKKQIRYIGLLNKDCIEKQLKIYHLSQSYLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4A1</accession>
    <name>D0Z4A1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000357</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304139.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39339">
        <property type="protein sequence ID" value="EEZ39339"/>
        <property type="gene ID" value="VDA_000357"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031MRU">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1228163at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003020073" evidence="1">
        <location>
            <begin position="20"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="289" mass="32541" checksum="ED889154FE59DA5C" modified="2010-01-19" version="1">MQRTTTHRLAIAVTVVALAGCSSTPKQQQPETNQLPVYKFTDVAHNFIAENAERSSGTVVDKGFFNPKKNNSFGYRYCASSPDAASTDMEAFKLLAQSTCDTNLGTMVDLPHGTWCVYNPNTPEEAPIFSAYISDSDLWTDLCPTGPFVTMKVNENREYTKDQWFKEAQVLGYEPYSIHRKVEPVKSGVRSESFRTTPATDKNLDTWADESYYIYKNVGATVCLVDKQKSVPYDVTYRGKVVSAKDGRVRVLATQKFKGDVRTAPKYEVLPWHKKAYINADVNSWFLCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4B6</accession>
    <name>D0Z4B6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative choline-glycine betaine transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_000372</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39354">
        <property type="protein sequence ID" value="EEZ39354"/>
        <property type="gene ID" value="VDA_000372"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1292">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071705">
        <property type="term" value="P:nitrogen compound transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018093">
        <property type="entry name" value="BCCT_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000060">
        <property type="entry name" value="BCCT_transptr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30047">
        <property type="entry name" value="PTHR30047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02028">
        <property type="entry name" value="BCCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00842">
        <property type="entry name" value="bcct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01303">
        <property type="entry name" value="BCCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="15"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="142"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="194"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="235"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="266"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="327"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="357"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="415"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="457"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="482"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="639" mass="70216" checksum="6298EB70D3E3EFEF" modified="2010-01-19" version="1">MIARKLNFQLIDRPTFFGALGLLISTVVPLLLFPKEGAEWIAIAKSFMTDKLGFLYLGLGVAAFFFMIYIVFSDIGQIKLGDPDEAPEFKTASWAAMLFCGGIGASILYWGAIEWAYYYQSPPFQLEPGSEEAVRWAATYGIFHWGPIAWSIYLVPALPIAYFFYVRKQPVLKVSAALMPVIGEARSHGWVGKLVDVLFIFGLLGGGATTLGLAAPLITEGVNYLFGVPKTTETQVVVLLVCTAIFAYSAYAGMEKGIKLLSNINFWGALGLLAFILICGPTIFMLETGLDSLGRMLSNFFVMATWAEPFGGYGSFADTHFPQDWTIFYWAWWLVFAPSMGLFVARISRGRTIKQMVTGSIFFGSMGCFLFFMILGNYGLSLQLSGALDVVGILNAEGATKAIFSILEQLPFSTFVIAAFTVLCLIFTATTFDSISYILASVVQNNVTEEPMRWNRLFWAFALSFMPSVLLFMGGLSTLQTAAIVGGLPLLVIAVMLMVSAVKAATLDLSHQEGYEDPTINIEELPDVDPWSKEGMALAKFEQLRDAAIEAADAEREALNAIWKLKKKMRAEALSRGDSGYELGDLPQEMHDELEQLTDAAMSAKDAKLAASEQAQEARVAFNDIMKQKILAETQEQTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4B7</accession>
    <name>D0Z4B7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000373</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304186.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000373"/>
    <dbReference type="EnsemblBacteria" id="EEZ39355">
        <property type="protein sequence ID" value="EEZ39355"/>
        <property type="gene ID" value="VDA_000373"/>
    </dbReference>
    <dbReference type="GeneID" id="57343246"/>
    <dbReference type="eggNOG" id="COG0388">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1583074at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001110">
        <property type="entry name" value="UPF0012_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="SSF56317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01227">
        <property type="entry name" value="UPF0012"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="3">
        <location>
            <begin position="8"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="CN hydrolase" evidence="2">
        <location>
            <begin position="224"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="503" mass="57403" checksum="AD0CAD50464CCEFC" modified="2010-01-19" version="1">MERSETLLNLRVIEAKDYPQIAELMDLVFHDVGGAWPRMTIMDLIHQFPDGQVCIEDNGKIIGAALTIKVDYNRFSSSHTYDEIINEHNVVQHNGNGDALYGLDVFVHPDYRGLRLGRRLYEARREMCFSHNLKAILAGGRIPGYKKVAHEMSVVEYIEQVKRRQLHDPILSFQLANGFDVKRIMKRYLPEDDSSQGYATLLEWNNFFYEDEVESIHDVEKTVVRLGVVQWQMRAMLSLDDLLDQAEFFVSSLSNYQADFALFPEFFSAPLMGLKKDQTSVEAVRYLAQFSEEIKNRFSQLAVTYNINIIAGSMPVVDGEHLYNIAYLLHRDGKIDEQCKVHITPHEQKDWVIDGGNKVEVFETDAGKVGILICYDVEFPELGRILAEQGVQILFVPFWTDTKNGYLRVRICAQARAIENECYVAIGGSVGNLPRVDNVDIQYAQSAVFSPSDIYFPHDAVITEASPNTEMIIFADVDLDKLKSLNREGSVTNLRHRRLDIYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4N8</accession>
    <name>D0Z4N8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF218 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000496</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304527.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39476">
        <property type="protein sequence ID" value="EEZ39476"/>
        <property type="gene ID" value="VDA_000496"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1434">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06259">
        <property type="entry name" value="YdcF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003848">
        <property type="entry name" value="DUF218"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02698">
        <property type="entry name" value="DUF218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF218" evidence="1">
        <location>
            <begin position="155"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="326" mass="37266" checksum="776FA090167FD2FA" modified="2010-01-19" version="1">MERTLALENAFTAFKSSNRTDYQVNGQLTNNIDAAILYLKQHLEQYPNDHYAALTLGNLYTFQGRYLAAFSIWQPLSNLPKVAHNAKIMNIACFYLATWHHYKDELFESEYFSQLLHKYAPKRSQHFDLLIHTLHHCLSLPIKHNLPNSNLNNHAIIVLGHQLNPDGTLSDFAKDRLKIAIKLKKKITNSLIFLTGGRAQNGMSEAQAMKQWLQERGIDHSDIVLEEQSRNTIENAQYTVPLLHLYAIESATIISNSIHVHRALLAFSLSNNKQENSAIEWQHVAVKDGLLANNMIDEETKRNCYIDALRCLDLPAFYCPPEMISV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4P1</accession>
    <name>D0Z4P1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Low-specificity L-threonine aldolase</fullName>
            <ecNumber evidence="6">4.1.2.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_000499</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the threonine aldolase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.5" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304539.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000499"/>
    <dbReference type="EnsemblBacteria" id="EEZ39479">
        <property type="protein sequence ID" value="EEZ39479"/>
        <property type="gene ID" value="VDA_000499"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2008">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1124266at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004793">
        <property type="term" value="F:threonine aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001597">
        <property type="entry name" value="ArAA_b-elim_lyase/Thr_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023603">
        <property type="entry name" value="Low_specificity_L-TA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48097:SF9">
        <property type="entry name" value="PTHR48097:SF9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01212">
        <property type="entry name" value="Beta_elim_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017617">
        <property type="entry name" value="Thr_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta_elim_lyase" evidence="5">
        <location>
            <begin position="2"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="4">
        <location>
            <position position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR017617-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ39479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="334" mass="36286" checksum="42AB9B1B80C89950" modified="2010-01-19" version="1">MDFRSDTVTQPTPAMREAMFSAPVGDDVYGDDPTVNELEAFAAHLAGFEAALFTTSGTQANLLGIMSHCDRGDEYLCGQQAHNYRYEAGGAAVLGSIQPQPIENNPDGTLPFDKLAAAIKPDDFHFARTKLLSLENTINGKVLPLAYLAQAREFTQQHNLQLHLDGARVFNAAVALDVPVKEIAQYFDSMTICLSKGLSAPVGSLLLGSKEFIAKARRIRKMLGGGMRQAGILAAAGKLALTEQVKQLSVDHDNAKYLAQELSQLSGFHVKPELVQTNIVFAKLDENIDISLIANQLKENGILVSPSNPIRFVTHKDISRDNITTLITQLKSVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4R0</accession>
    <name>D0Z4R0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Anaerobic dimethyl sulfoxide reductase chain C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000518</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304598.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000518"/>
    <dbReference type="EnsemblBacteria" id="EEZ39498">
        <property type="protein sequence ID" value="EEZ39498"/>
        <property type="gene ID" value="VDA_000518"/>
    </dbReference>
    <dbReference type="GeneID" id="57342801"/>
    <dbReference type="eggNOG" id="COG3302">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="909963at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019645">
        <property type="term" value="P:anaerobic electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007059">
        <property type="entry name" value="DmsC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04976">
        <property type="entry name" value="DmsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="199"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="230"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="252" mass="27372" checksum="D60F3035491CD74A" modified="2010-01-19" version="1">MLWSDWPLLLSSVLAQLAIGAFLFLGGAILTGKLCFGQNDRVQRTLPGLWFLLFASLVIREVTLMFSQTYVAKPIGTETLFAISFFALALTYWFAEKQLMGNDTARKILLSCAIFMGCAYFVVGIMLRSNHLLVAMHFVATTLCGGALLAHALLVKAEHKVTEFNTWLPFIGAGIALLCLVLGIPQLGDLATQANQGELGPFVAQVISLGLLIAAVGVWFMPLLTKSKPVWNVMAFAIFLIFLSSYGAAVGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z540</accession>
    <name>D0Z540_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH araC/xylS-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306815.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000004.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39074">
        <property type="protein sequence ID" value="EEZ39074"/>
        <property type="gene ID" value="VDA_000090"/>
    </dbReference>
    <dbReference type="OrthoDB" id="236365at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="1">
        <location>
            <begin position="175"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="280" mass="32349" checksum="A7386A9F6FD59D93" modified="2010-01-19" version="1">MEYKLYKCKLSNISGSSNSNKSLNVPFVTIIIINSGTIIINNKKNKRGDVVILKPNKDYVIELISDEIISRYDVDVLVMDSQDIDFVSKYLNPYQGLNEEKITSLTSMDKEFFVIKSSTSIRKLLEYFFYSDKSNHELASSAFNISLLGICSEICIRDIRFLSYLNLYRNIDVYNKIIENIYLWINKGCYNANELYLKLDFDKEYVDKILKDNNTTLKKCLEKCRSVIAIREIINTTDSLSNIAFRNGYSSSSSFTKKIKGIYGYSPIEIRKIFNHNCVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z587</accession>
    <name>D0Z587_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">IncF plasmid conjugative transfer protein TraD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000047</name>
        <name evidence="5" type="ORF">VDA_000137</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000005">
        <property type="protein sequence ID" value="EEZ39062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306953.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000005.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000047"/>
    <dbReference type="EnsemblBacteria" id="EEZ39062">
        <property type="protein sequence ID" value="EEZ39062"/>
        <property type="gene ID" value="VDA_000047"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39121">
        <property type="protein sequence ID" value="EEZ39121"/>
        <property type="gene ID" value="VDA_000137"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3505">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="246216at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014128">
        <property type="entry name" value="T4SS_TraD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019476">
        <property type="entry name" value="T4SS_TraD_DNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10412">
        <property type="entry name" value="TrwB_AAD_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02759">
        <property type="entry name" value="TraD_Ftype"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="33"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="domain" description="TrwB_AAD_bind" evidence="3">
        <location>
            <begin position="181"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="625"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="636"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="697"/>
            <end position="711"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="711" mass="82006" checksum="0F49AA0E7DF13173" modified="2010-01-19" version="1">MLIKHKARPKSNTKAFTRGGQITFHNLRMYFQILAVIGSWSMVIAFIFTALFAYFLIDIDQLLALKYYFHAKYLALPDTKIMVMYQGQEYPYTAEKLLSSERFNASVDDVFLDIQLAFIFSFFAVMIAFMKVTKYFEKKGEEQTQDYLIRGTEIATPQELERRLKKDKNTSPFKLDGLSLLPNNFEIRHLSFSGSTGTGKSVAIRKLLREIRARGDKAIIYDKGCTFVSRFYDEHKDYILNPFDERSVDWKIWYDAQEFSDFESLSTALIADSGHGDPFWIESARTLFTNTAYQMTQDGKPLTNERLLDYILKTPTSVLREFLKGTMASAITDEKADKIAISVKSILAAYIKSLRYLEGLDQQDKNGKRRKAFSVRDWVLDDNEKGFLFLTSNAQQHVSLRPLISMWLSTASTAILGLDESTTRRIWVITDELPSLHRLPDLASTLAEVRKHGGCYLVGFQSFAQFVKIYGRDAAEEMYDLLNTRFYFRNPSAPQAEKSSKDLGEQEIEISKEQYSYGANSVRDGISLGHQTITRPAVMTSEIMALDDLQCWYRTFGGYPITRINFKFDDMASVAVPFIKRVYDSSDTMKRIDGELAHYQMGALLALPDEDKQVLLNIHKARHNNEQGDCDQSSYDNECEQMKETVKENNERIEKEQPEKEKSRNDDQDIEKQKMKEEQELKRQMSADDQTEQAFRETEETMINNDMTPFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5F2</accession>
    <name>D0Z5F2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Serine protease</fullName>
            <ecNumber evidence="3">3.4.21.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_000059</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the peptidase S1B family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000006">
        <property type="protein sequence ID" value="EEZ39004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005307118.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000006.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000059"/>
    <dbReference type="EnsemblBacteria" id="EEZ39004">
        <property type="protein sequence ID" value="EEZ39004"/>
        <property type="gene ID" value="VDA_000059"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3591">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1635087at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020008">
        <property type="entry name" value="GlyGly_CTERM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008256">
        <property type="entry name" value="Peptidase_S1B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00839">
        <property type="entry name" value="V8PROTEASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03501">
        <property type="entry name" value="GlyGly_CTERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0720">Serine protease</keyword>
    <keyword evidence="2 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006991147" description="Serine protease" evidence="3">
        <location>
            <begin position="22"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="5">
        <location>
            <begin position="22"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="291"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ39004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="340" mass="36384" checksum="F06B43EB18F67692" modified="2010-01-19" version="1">MKQISLLALGITSLFSVPSYAVEDGVSLSWDKYPYIVESQCTGTVIAGKYILLAGHCGASIDNPFPRVVNFADGSTMMPIHRNAEPYYQEKKSADIALWTLPKTAPMNTIAFIDNLNDPNTIPTVGDKVSFIGFGQNDNIPRLGKGINSIIEEYPSVLIYGNSQSYSVPGDSGAPVFNEQNKIIAINYAGAGSIDRNQNGVNLRFVKDWLLQNINAWHSPTELKFTGSNTIEIQSLHVKNTNLALRQNNGALSSGDVTVTGGSCITDGDVTPFGTCTLELSSTGGEGHIMLDDGNTITINRAPKPEPKPDPQPSNGGGSGGSMGYLSLLGLLVLAFKRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5F9</accession>
    <name>D0Z5F9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000066</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000006">
        <property type="protein sequence ID" value="EEZ39011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005307137.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000006.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39011">
        <property type="protein sequence ID" value="EEZ39011"/>
        <property type="gene ID" value="VDA_000066"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031Q58">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="182" mass="20748" checksum="88961802EA236C9B" modified="2010-01-19" version="1">MKKNQTSLDNVNLHSKRLVSLWQHDHFKNKGFKHVDGAFISSNIFSVYVYSTSKNESVIKALAMRVDNKISDLIGDTRQYIRQEQRKLDRMATTSIVSNFVKPDAIDITINKDKITPNVLALIKLFIAVDNHIITANKAKVDGDISSTECSAYQSHAFKKINVLLTELKKICSQFHQIRKNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5I8</accession>
    <name>D0Z5I8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Rep_3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000006</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000007">
        <property type="protein sequence ID" value="EEZ38999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ38999">
        <property type="protein sequence ID" value="EEZ38999"/>
        <property type="gene ID" value="VDA_000006"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000525">
        <property type="entry name" value="Initiator_Rep_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01051">
        <property type="entry name" value="Rep_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rep_3" evidence="1">
        <location>
            <begin position="4"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ38999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="326" mass="37299" checksum="DB015AB6402BDE43" modified="2010-01-19" version="1">MKPTTITKSHPLITAKMSFTAKEQDLLNLILVSLKKEANAQKKTSKLKNLPVSDKNDGVHIDKLSLQYEYTRQELLDLLEVTPKRLTAYLDEATDELMEKVATVRNPNTGEYRKYKLVGFSSWEANVLTLSIDKEVAEVLLNYSAGFAVIDFKLMFALKNKNEKRILDLISRFKGKKNTFFKCRIKDLCEMLGVSYGDYANYNSFRIAVLSQPLARIIKASNGLWEYMPDCKTGIKIYKKGRATTENDFVELRVCYVKQVEEKQYQVDIPEELLELSAVVAAWRKGTAPTQMQAMDILMEIDELEKSELLTKNDFKKLRKAVPPQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVH4</accession>
    <name>D0YVH4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative DNA uptake protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001554</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298268.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001554"/>
    <dbReference type="EnsemblBacteria" id="EEZ40528">
        <property type="protein sequence ID" value="EEZ40528"/>
        <property type="gene ID" value="VDA_001554"/>
    </dbReference>
    <dbReference type="GeneID" id="57342388"/>
    <dbReference type="eggNOG" id="COG1555">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1948240at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004509">
        <property type="entry name" value="Competence_ComEA_HhH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00426">
        <property type="entry name" value="TIGR00426"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019147" evidence="1">
        <location>
            <begin position="23"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="95" mass="10446" checksum="45E7E995712A3DB7" modified="2010-01-19" version="1">MKQGFVAVVMALAMLLTPLAYAAKDKYEDIEIVVNINKANAEELDKLLVGIGPDKAENIIQYRKQNGKFATADDLAKVKGIGPSTVEKNRDRIEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-12-02" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVI7</accession>
    <name>D0YVI7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001567</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001567"/>
    <dbReference type="EnsemblBacteria" id="EEZ40541">
        <property type="protein sequence ID" value="EEZ40541"/>
        <property type="gene ID" value="VDA_001567"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025996">
        <property type="entry name" value="TetR_C_WHG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13305">
        <property type="entry name" value="TetR_C_33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TetR_C_33" evidence="4">
        <location>
            <begin position="11"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="121" mass="13938" checksum="4A4E146B1E8F09FE" modified="2010-01-19" version="1">MKEATSAEDALRRLAYCYLEFATQHPYRWQLIFQHTMNGEDLPEWQSERIDNMTGMLEALIRQITPNKSEDEILEASRVLWAGVHGITLLTVDDKLFTSTPVDGKALIDNLLNTYLNAWHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVP2</accession>
    <name>D0YVP2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ferric iron ABC transporter permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_001207</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297638.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001207"/>
    <dbReference type="EnsemblBacteria" id="EEZ40185">
        <property type="protein sequence ID" value="EEZ40185"/>
        <property type="gene ID" value="VDA_001207"/>
    </dbReference>
    <dbReference type="GeneID" id="57339937"/>
    <dbReference type="eggNOG" id="COG1178">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1783638at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="53"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="88"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="196"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="238"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="287"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="329"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="363"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="407"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="466"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="515"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="50"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="328"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="541" mass="60384" checksum="7BA283BCD7AB3172" modified="2010-01-19" version="1">MKEKFLFWQTSSWSLSLLLVLPILAIFFTALGQSDQVFSHLLNTVMPTYLANTFWVVVGTVVLALLFGVPSAWIMAMCKVPSEKTLQWALVLPLAMPGYIVGYIYTDWFDYAGPIQIFLRDLFGWQTAAEYWFPNFRSIGGACFVLALVLYPYIYLLVRAAFMEQSVSLLQSARLLRCNPWQSFCRVSLPLVRPAIAVGVSLVAMETLGDFGTVSYFAVNTLTTAVYDTWLGYSNLHAAAKISALMLVVIFILISAERFSRRKQKLFQQQLNGSDSVRYTLTGWKKWLAVIWCWGLVTVAFILPMLQLADYAWTYFGQSWTEAFRQYSINSFVVSIVAAVIALFIALLVNFSHRLVPSKFNTVPIRLASMGYAVPGTVLAIGVMIPLTGADHFINDVAKSLEWGRPGLILSGSMFAMIFAFVVRFSAVAIGSIESSLAKVSPSLDMASKTMGVASFKMLRRVHFPLVRRGCLIAVILVFIESMKELNAALLLRPFNFETLATYVFNYASDEHLELAALPAILLILVGLVPLILVNRSLEQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVQ7</accession>
    <name>D0YVQ7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 9">Catalase-peroxidase</fullName>
            <shortName evidence="8">CP</shortName>
            <ecNumber evidence="8 9">1.11.1.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Peroxidase/catalase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">katG</name>
        <name evidence="12" type="ORF">VDA_001998</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8 9">
            <text>2 H2O2 = 2 H2O + O2</text>
            <dbReference type="Rhea" id="RHEA:20309"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="EC" id="1.11.1.21"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>AH2 + H2O2 = A + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:30275"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="EC" id="1.11.1.21"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
        <text evidence="8">Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer or homotetramer.</text>
    </comment>
    <comment type="PTM">
        <text evidence="8">Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8 9">Belongs to the peroxidase family. Peroxidase/catalase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.21" evidence="8 9"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299132.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001998"/>
    <dbReference type="EnsemblBacteria" id="EEZ40966">
        <property type="protein sequence ID" value="EEZ40966"/>
        <property type="gene ID" value="VDA_001998"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0376">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="49441at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004096">
        <property type="term" value="F:catalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01961">
        <property type="entry name" value="Catal_peroxid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000763">
        <property type="entry name" value="Catalase_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019794">
        <property type="entry name" value="Peroxidases_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019793">
        <property type="entry name" value="Peroxidases_heam-ligand_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30555">
        <property type="entry name" value="PTHR30555"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00460">
        <property type="entry name" value="BPEROXIDASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00458">
        <property type="entry name" value="PEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="SSF48113"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00198">
        <property type="entry name" value="cat_per_HPI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00435">
        <property type="entry name" value="PEROXIDASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00436">
        <property type="entry name" value="PEROXIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="7 8 9" id="KW-0376">Hydrogen peroxide</keyword>
    <keyword evidence="6 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 8 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 8 9" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PEROXIDASE_4" evidence="11">
        <location>
            <begin position="131"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="98"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="265"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="8">
        <location>
            <position position="94"/>
        </location>
    </feature>
    <feature type="cross-link" description="Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-97)" evidence="8">
        <location>
            <begin position="224"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ40966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="728" mass="81140" checksum="6EED6894899CDE67" modified="2010-01-19" version="1">MSKCPFHNNETVVNPAVNPGNGTSPSDWWPNQLKLDLLHQHDRKSNPMGEDFDYAAEFKTLDLEAVKQDLRDLMTDSQEWWPADFGHYGPFFIRMAWHSAGTYRTGDGRGGAGTGNQRFAPLNSWPDNVNLDKARRLIWPIKQKYGKKISWADLMILTGNVALESMGFKTLGFAGGRQDIWEPELDIYWGKETAWLADDTRYEKEEEQRDLENPLAAVQMGLIYVNPEGPDGNPDPLLAAHDIRETFARMAMDDEETVALIAGGHTFGKTHGAGDAAHVGPEPEAAGIAEQGLGWTSSFGSGKAGDTISSGLEVTWTTTPTEWSNGFFSSLFYNEWELEKSPAGAYQWVSKGGEVHPDAFDPNKKHKATMLTTDLSLRFDPAYEKISRRFFEKPQEFADAFARAWFKLTHRDMGPRARYLGSEVPAQEFIWQDPIPAVNHELVDDADIAKLKQEIAASGLSVRELVSTAWASASTFRGSDMRGGANGARIRLSPQKDWVANEPEQLDKVLNVLEGIQARFEKTVSLADLIVLAGGVGIEMAAKNAGRDISVPFAPGRMDASQEQTDVHSFAVLEPMADGFRNFEKKKFSVSQEELLLDRAQLLKLTAPEMTVLVGGMRVLDTNHDHTQYGVFTERKEALTNDFFVNLLDMATSWKPTSVDEDVFVGTDRKTGEEKWTATRVDLVFGSNSQLRALAEVYACADSEEKFVNDFVNAWVKVMNADRFDLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVU9</accession>
    <name>D0YVU9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cytidine deaminase</fullName>
            <ecNumber evidence="4">3.5.4.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Cytidine aminohydrolase</fullName>
            <shortName evidence="4">CDA</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">cdd</name>
        <name evidence="6" type="ORF">VDA_002030</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>2'-deoxycytidine + H(+) + H2O = 2'-deoxyuridine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:13433"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15698"/>
            <dbReference type="ChEBI" id="CHEBI:16450"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>cytidine + H(+) + H2O = NH4(+) + uridine</text>
            <dbReference type="Rhea" id="RHEA:16069"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16704"/>
            <dbReference type="ChEBI" id="CHEBI:17562"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="4">Binds 1 zinc ion.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1 4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cytidine and deoxycytidylate deaminase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.5" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299223.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002030"/>
    <dbReference type="EnsemblBacteria" id="EEZ40998">
        <property type="protein sequence ID" value="EEZ40998"/>
        <property type="gene ID" value="VDA_002030"/>
    </dbReference>
    <dbReference type="GeneID" id="57341826"/>
    <dbReference type="eggNOG" id="COG0295">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="959039at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004126">
        <property type="term" value="F:cytidine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047844">
        <property type="term" value="F:deoxycytidine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01558">
        <property type="entry name" value="Cyt_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016192">
        <property type="entry name" value="APOBEC/CMP_deaminase_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013171">
        <property type="entry name" value="Cyd/dCyd_deaminase_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006263">
        <property type="entry name" value="Cyt_deam_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020797">
        <property type="entry name" value="Cytidine_deaminase_bacteria"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08211">
        <property type="entry name" value="dCMP_cyt_deam_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01355">
        <property type="entry name" value="cyt_deam_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00903">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="5">
        <location>
            <begin position="48"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="5">
        <location>
            <begin position="187"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="89"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="104"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="295" mass="31831" checksum="5652F7D2CF616807" modified="2010-01-19" version="1">MHAKVMDALGNLPTELKTVLLPIIEDPQFDATISPDQFDYLLSQTQMSDSDLRVALLPIAAAYSVAPISNFYVGAIVRGLSGRLYFGANMEITGASLSQTVHAEQSAISHAWVKGETGISDITINYSPCGHCRQFMNELTTAKELEVQLPQRAAKTLQEYLPESFGPADLQITDALLAEVNNGLVIEESAELAQQACKAANRAHAPYTKNFSGVALKADDGRIFTGMYAENAAFNPSLPPLQVALIGMNMAGYTFDKIVEAALVEKQDSTITHVNDTQALLEAINPDIPLLYVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVX9</accession>
    <name>D0YVX9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Elongation factor 4</fullName>
            <shortName evidence="6">EF-4</shortName>
            <ecNumber evidence="6">3.6.5.n1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Ribosomal back-translocase LepA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">lepA</name>
        <name evidence="8" type="ORF">VDA_001260</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>GTP + H2O = GDP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.n1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Peripheral membrane protein</topology>
            <orientation evidence="6">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.n1" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001260"/>
    <dbReference type="EnsemblBacteria" id="EEZ40238">
        <property type="protein sequence ID" value="EEZ40238"/>
        <property type="gene ID" value="VDA_001260"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0481">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045727">
        <property type="term" value="P:positive regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03709">
        <property type="entry name" value="lepA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00071">
        <property type="entry name" value="LepA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006297">
        <property type="entry name" value="EF-4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038363">
        <property type="entry name" value="LepA_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013842">
        <property type="entry name" value="LepA_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035654">
        <property type="entry name" value="LepA_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43512">
        <property type="entry name" value="PTHR43512"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06421">
        <property type="entry name" value="LepA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01393">
        <property type="entry name" value="lepA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="4 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="7">
        <location>
            <begin position="1"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="88"/>
            <end position="91"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ40238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="555" mass="61307" checksum="F0EC735D92B69479" modified="2010-01-19" version="1">MDLERERGITIKAQSVTLDYTAKDGETYQLNFIDTPGHVDFSYEVSRSLAACEGALLVVDAGQGVEAQTLANCYTAIEMDLEVVPILNKIDLPAAEPERVSEEIEDIVGIDAIDAVRCSAKTGLGVDDVLEKIVEAIPSPEGDPDAPLQALIIDSWFDNYLGVVSLVRIKNGQLKKNDKIKVMSTGQTWGVDRLGIFTPKQVDKTVLNTGEVGWVVCGIKDILGAPVGDTLTLAKNGCETALPGFKKVKPQVYAGLFPVSSDDYENFRDALGKLSLNDASLFYEPESSSALGFGFRCGFLGMLHMEIIQERLEREYDLDLITTAPTVVYEVKKTSGETLYVDSPAKLPAVNDIEVIGEPIARCNILVPSDYLGNVITLCVEKRGVQVDMVYHGNQVALTYDIPMSEVVLDFFDRLKSTSRGYASLDYNFQRYEESDMVRVDILLNGERVDALAIITHKENSQGRGRDLVEKMKEFIPRQMFDIAIQAAIGNHIIARSTVKQLRKNVIAKCYGGDVSRKKKLLQKQKEGKKRMKQIGNVELPQEAFLAILHVGKDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWC4</accession>
    <name>D0YWC4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Oligopeptide transport system permease protein OppC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_001387</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297978.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001387"/>
    <dbReference type="EnsemblBacteria" id="EEZ40362">
        <property type="protein sequence ID" value="EEZ40362"/>
        <property type="gene ID" value="VDA_001387"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4239">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1734230at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="146"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="183"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="207"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="260"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="311"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="143"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="347" mass="38983" checksum="1C182C68BDE6667F" modified="2010-01-19" version="1">MIKLNPLTKKKIDRFKSLKRGYFSFCLLSLCLLLSLMAEVLINSKALVVRYQGEYFFPVFSQVIQGQKFGLATHGETDYRLLQQKFRQQDMGDFVIMPLVPWNPYEQDFSGAYPPTPPSIAEQHYLGTDVIGRDILARLVYGFRTAMGFALITMAISYAIGAVVGCAMGFFGGKFDLIVQRLIEIWSMVPFLYVIMILVSITQPTFALFVAINVLFGWMGMTWYMRTMTYKESAREYVLAAKALGASTWRIICHHILPNTMVMIVTLAPFTIAANITALTALDYLGLGLMPPTPSWGELLQQGKSNLDSPWIATSVVTAIVLVLVMVTFIGEAIRAAFDPKRLTRYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWI5</accession>
    <name>D0YWI5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">dITP/XTP pyrophosphatase</fullName>
            <ecNumber evidence="7">3.6.1.66</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Non-canonical purine NTP pyrophosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Non-standard purine NTP pyrophosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Nucleoside-triphosphate diphosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Nucleoside-triphosphate pyrophosphatase</fullName>
            <shortName evidence="7">NTPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_001227</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>H2O + ITP = diphosphate + H(+) + IMP</text>
            <dbReference type="Rhea" id="RHEA:29399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:61402"/>
            <dbReference type="EC" id="3.6.1.66"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>H2O + XTP = diphosphate + H(+) + XMP</text>
            <dbReference type="Rhea" id="RHEA:28610"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:61314"/>
            <dbReference type="EC" id="3.6.1.66"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>dITP + H2O = dIMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:28342"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61194"/>
            <dbReference type="ChEBI" id="CHEBI:61382"/>
            <dbReference type="EC" id="3.6.1.66"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="7">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the HAM1 NTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.66" evidence="7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297680.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001227"/>
    <dbReference type="EnsemblBacteria" id="EEZ40205">
        <property type="protein sequence ID" value="EEZ40205"/>
        <property type="gene ID" value="VDA_001227"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0127">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1824064at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035870">
        <property type="term" value="F:dITP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036220">
        <property type="term" value="F:ITP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017111">
        <property type="term" value="F:nucleoside-triphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036222">
        <property type="term" value="F:XTP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009146">
        <property type="term" value="P:purine nucleoside triphosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00515">
        <property type="entry name" value="HAM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01405">
        <property type="entry name" value="Non_canon_purine_NTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020922">
        <property type="entry name" value="dITP/XTP_pyrophosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002637">
        <property type="entry name" value="Ham1p-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029001">
        <property type="entry name" value="ITPase-like_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11067">
        <property type="entry name" value="PTHR11067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01725">
        <property type="entry name" value="Ham1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52972">
        <property type="entry name" value="SSF52972"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00042">
        <property type="entry name" value="TIGR00042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 7" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="8"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="154"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="182"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="69"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ40205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="197" mass="21552" checksum="66CD64A703BBF781" modified="2010-01-19" version="1">MSKLVLATGNQGKVKEMADLLSDFGFNVVAQSDFNVSSVAETGTTFIENAIIKARHAAKETGLPAIADDSGLEVDYLQGAPGIYSARYAGEDASDSANIDKLLVAMENVPEDQRTARFHCVLVMMRHENDPTPLVCHGRWEGRILTERLGENGFGYDPIFWVPEDQCSSAQLEPARKKQLSHRGQALQQLFAALKDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWI9</accession>
    <name>D0YWI9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Twitching motility protein PilT</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001231</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GSP E family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297689.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001231"/>
    <dbReference type="EnsemblBacteria" id="EEZ40209">
        <property type="protein sequence ID" value="EEZ40209"/>
        <property type="gene ID" value="VDA_001231"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2805">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="473670at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01131">
        <property type="entry name" value="PilT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006321">
        <property type="entry name" value="PilT/PilU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001482">
        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00437">
        <property type="entry name" value="T2SSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01420">
        <property type="entry name" value="pilT_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00662">
        <property type="entry name" value="T2SP_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T2SP_E" evidence="2">
        <location>
            <begin position="193"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="344" mass="38181" checksum="6F6A4BDE4DB79CF8" modified="2010-01-19" version="1">MDITELLDFSVKHNASDLHLSAGVPPMIRVDGDVRKLSLPALEHSEVHRLIFDIMNDAQRRQFEEELEVDFSFELPDVGRFRVNAFHQSRGCSAVFRTIPMTIPTLESLNVPDVFYKIAQCQRGLVLVTGATGSGKSTTIAALVDYINEHTNRHILTIEDPIEFVHHSKRCLINQREVHRDTHSFQAALRSALREDPDVIVVGELRDQETISLALTAAETGHLVLGTLHTSSAAKSIDRIIDVFPGSDKSMVRSMLSESLRAVVSQSLLKCISGGRVASHEIMMATPAIRNLIREDKIAQMYSMIQTGSAMGMQTMEQSVKMLVAQGLVEAEEGRRIVDSAQQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWK0</accession>
    <name>D0YWK0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7 10">Phosphoglycerate kinase</fullName>
            <ecNumber evidence="2 7 10">2.7.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pgk</name>
        <name evidence="11" type="ORF">VDA_001241</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7 10">
            <text>(2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:14801"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57604"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7 10">Belongs to the phosphoglycerate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.3" evidence="2 7 10"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297708.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001241"/>
    <dbReference type="EnsemblBacteria" id="EEZ40219">
        <property type="protein sequence ID" value="EEZ40219"/>
        <property type="gene ID" value="VDA_001241"/>
    </dbReference>
    <dbReference type="GeneID" id="57339880"/>
    <dbReference type="eggNOG" id="COG0126">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="462069at2"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00185"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004618">
        <property type="term" value="F:phosphoglycerate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1260">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00145">
        <property type="entry name" value="Phosphoglyc_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001576">
        <property type="entry name" value="Phosphoglycerate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015911">
        <property type="entry name" value="Phosphoglycerate_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015824">
        <property type="entry name" value="Phosphoglycerate_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036043">
        <property type="entry name" value="Phosphoglycerate_kinase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11406">
        <property type="entry name" value="PTHR11406"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00162">
        <property type="entry name" value="PGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000724">
        <property type="entry name" value="Pgk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00477">
        <property type="entry name" value="PHGLYCKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53748">
        <property type="entry name" value="SSF53748"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00111">
        <property type="entry name" value="PGLYCERATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="5 7 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 10" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="7 8">
        <location>
            <begin position="21"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7 8">
        <location>
            <begin position="59"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7 8">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 8">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 8">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="314"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <begin position="340"/>
            <end position="343"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000724-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000724-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ40219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="387" mass="40744" checksum="A4CD0F44E8011E92" modified="2010-01-19" version="1">MSVIKMTDLDLAGKRVFIRADLNVPVKDGKVTSDARILASLPTIKHCLEAGAKVMVTSHLGRPTEGEYAEEFSLQPVVNYLNDALDCDVKLAKDYLDGLELNAGELVVLENVRFNKGEKKNEDELSKKYAALCDVFVMDAFGTAHRAQASTYGVGMFAPIACAGPLLANELEALGKAMDNPARPMVAIVGGSKVSTKLTVLESLSKIADQIVVGGGIANTFIAAEGNDVGKSLYEADLIGTAKELMAQTSIPVATDVVCAKEFSESAEATVKAATEIAADDMVLDIGPDSAAELARIIKDAKTILWNGPVGVFEIDQFGKGTEVVAKAIAESEGFSVAGGGDTLAAIDKYGIKDQVSYISTGGGAFLEFVEGKKLPAVEMLETRAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWR1</accession>
    <name>D0YWR1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Lead cadmium zinc and mercury transporting ATPase</fullName>
            <ecNumber evidence="12">3.6.3.3</ecNumber>
            <ecNumber evidence="12">3.6.3.4</ecNumber>
            <ecNumber evidence="12">3.6.3.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">VDA_001458</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.3" evidence="12"/>
    <dbReference type="EC" id="3.6.3.4" evidence="12"/>
    <dbReference type="EC" id="3.6.3.5" evidence="12"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298095.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001458"/>
    <dbReference type="EnsemblBacteria" id="EEZ40432">
        <property type="protein sequence ID" value="EEZ40432"/>
        <property type="gene ID" value="VDA_001458"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2217">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="237367at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006825">
        <property type="term" value="P:copper ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017969">
        <property type="entry name" value="Heavy-metal-associated_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006122">
        <property type="entry name" value="HMA_Cu_ion-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027256">
        <property type="entry name" value="P-typ_ATPase_IB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="SSF55008"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01525">
        <property type="entry name" value="ATPase-IB_hvy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00003">
        <property type="entry name" value="TIGR00003"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01047">
        <property type="entry name" value="HMA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0186">Copper</keyword>
    <keyword evidence="5" id="KW-0187">Copper transport</keyword>
    <keyword evidence="12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="313"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="340"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="379"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="407"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="563"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="588"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="904"/>
            <end position="923"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="929"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="11">
        <location>
            <begin position="65"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="11">
        <location>
            <begin position="132"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="11">
        <location>
            <begin position="223"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ40432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="962" mass="102386" checksum="AE5B6405049650BD" modified="2010-01-19" version="1">MSRFDLPMQNVRCMGCVKKIRAAIETLPNTVIHDIDTDHIDVSSDAPLSSLFSIIEELGYNVGYHYQFTLQGLSCGHCVAKVEAALKAQNDVVSYQVSTTNLDVTGAISKQSLIELIDSLGYQALDESEPTTIMLYLSGLSCGKCVAKLKAAFEAQSVSVLEIETKHAVVSSNLNAEQLLTIVTDAGYQASLTEPQDTQPAEGIVIPEAISQPTENKQSIATTQQFLLSGMTCASCVASVEKAIASVTGVESVNVNLAERTALVSGDGQTQAIIHAVEQAGYGAELSENEDERRARQQEQNSQTYKTHIKNSITALVVGVPLMAWGVFGGNMMINSTSSQISWGIIGLITLWLLCTVGKHFYINAWKAFLHHRATMDTLVALGTGAAWIFSMLIVIMPNVFPPTARHVYFEASAMILGLITLGHALESRARSQTSKALERLIDLQPQTAIIVENGVEVERPLSDVTEGMTLRLHPGAKVPVDGIVLDGQSYIDESMLTGEPIPANKTAGEKVHAGTINQHGSLLFKAEQIGANTMLSRIIQLVRQAQSSKPALARLADKISSIFVPSVMIIAIVTAMVWYYFGPAPSSIYMLVAATTVLIIACPCALGLATPMSVTVGVGRAAEMGILIRDAEAMQLAADVDTVVLDKTGTLTEGKPALTQTVALANLNDEQIIQLAASLEQGSEHPLAIAILDAAKEKQLTLTKPINFTARPGFGVSGDVNQTNISLGNARLMAEHSIDVTHYQEQTTEIASQGATPIYVAVDNTLVGILAISDPLREDSITAVSRMQKMGLNVVMLTGDTEVTAHAIAKKVGIETIIAGVLPDGKAEQVAKLQQQGHKVAMVGDGINDAPALARAEVGIAMGSGSDVAIESAQFTLMRHSLHAVADALELSKATLKNMKENLFGAFVYNSLGIPVAAGILYPITGTLLSPVIAGAAMALSSITVVTNANRLRLFKPQHKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWS4</accession>
    <name>D0YWS4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Outer membrane protein C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001469</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell outer membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001469"/>
    <dbReference type="EnsemblBacteria" id="EEZ40443">
        <property type="protein sequence ID" value="EEZ40443"/>
        <property type="gene ID" value="VDA_001469"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015288">
        <property type="term" value="F:porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00342">
        <property type="entry name" value="gram_neg_porins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033900">
        <property type="entry name" value="Gram_neg_porin_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="342" mass="37543" checksum="4588AC48BC6BCA5E" modified="2010-01-19" version="1">MVSTVQAATIYQAEDGSHVDVYGRLGFNITDRDNDGDKSHVDGNFDGRIGLGGSQTVNDKVSVIGWAEYQVNAAEGANAGKGNDSLSARYVWAGIDASEYGKITGGRVASGLIMLTDIADVFAASDVTIGRQVSAIDSTATQVFRQDGTLQYQNTFGALDVSAAYILGNSTSDLKTAYNGALRYTLDLGNAGKLAPVVAYQYDETDNKNNDAKDYTFWGVGTRYYIEKLMLGAMYSEGELGFFDSREKSKDKVYELTAVYDLNDSWALRAGYRSLENEGGDETEYKDTTLEAQYKLTDRSSIFTSYVFRDGKKGNGSIPSIDWNGWNNPEEDYFHVGLRYEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX80</accession>
    <name>D0YX80_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phosphofructokinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_001939</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + beta-D-fructose 1-phosphate = ADP + beta-D-fructose 1,6-bisphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14213"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:138881"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.56"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the carbohydrate kinase PfkB family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298978.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001939"/>
    <dbReference type="EnsemblBacteria" id="EEZ40907">
        <property type="protein sequence ID" value="EEZ40907"/>
        <property type="gene ID" value="VDA_001939"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1105">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1323781at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008662">
        <property type="term" value="F:1-phosphofructokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01164">
        <property type="entry name" value="FruK_PfkB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022463">
        <property type="entry name" value="1-PFruKinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017583">
        <property type="entry name" value="Tagatose/fructose_Pkinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000535">
        <property type="entry name" value="1PFK/6PFK/LacC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03168">
        <property type="entry name" value="1-PFK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03828">
        <property type="entry name" value="pfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00583">
        <property type="entry name" value="PFKB_KINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="6">
        <location>
            <begin position="26"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR000535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="315" mass="33522" checksum="DA9269F824B06B9F" modified="2010-01-19" version="1">MTNQMKKVVAVTLNPALDLTGSLASLQTGSVNLIDSSDFHPAGKGVNVAKVLSDLGAQVTVTGLLGEDNQEAFNQLFNELGVNEQFVRVPGATRINVKLVENSGQVTDLNFPGIYVTDADIARFEQTLFLLAESHDVFVIAGSLPKGISPELCASWVEKLGQLGKQVFFDSSKAALAAGLDAQPWLIKPNDEELGDFLGKELTTQKQIIEAAETLAQKKISNVVISLGAEGVLWLNQEGWLASKPPKMQVVSTVGAGDTLVAGLCWGHINGWNKETSLRFATALSALAVSQVGVGAEDHDGIKQVEQQVQITTVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX89</accession>
    <name>D0YX89_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">L-threonine 3-dehydrogenase</fullName>
            <shortName evidence="6">TDH</shortName>
            <ecNumber evidence="6">1.1.1.103</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">tdh</name>
        <name evidence="8" type="ORF">VDA_001948</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-threonine + NAD(+) = (2S)-2-amino-3-oxobutanoate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:13161"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:78948"/>
            <dbReference type="EC" id="1.1.1.103"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Amino-acid degradation; L-threonine degradation via oxydo-reductase pathway; glycine from L-threonine: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.103" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298994.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001948"/>
    <dbReference type="EnsemblBacteria" id="EEZ40916">
        <property type="protein sequence ID" value="EEZ40916"/>
        <property type="gene ID" value="VDA_001948"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1063">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="972769at2"/>
    <dbReference type="UniPathway" id="UPA00046">
        <property type="reaction ID" value="UER00505"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008743">
        <property type="term" value="F:L-threonine 3-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019518">
        <property type="term" value="P:L-threonine catabolic process to glycine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00627">
        <property type="entry name" value="Thr_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004627">
        <property type="entry name" value="L-Threonine_3-DHase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00692">
        <property type="entry name" value="tdh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0520">NAD</keyword>
    <keyword evidence="4 6 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="PKS_ER" evidence="7">
        <location>
            <begin position="14"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="42"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="45"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="264"/>
            <end position="266"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="288"/>
            <end position="289"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity for the proton relay mechanism but does not participate directly in the coordination of zinc atom" evidence="6">
        <location>
            <position position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ40916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="343" mass="37673" checksum="10AC24DD633C719B" modified="2010-01-19" version="1">MKIKALSKLKPEQGIWMTEVDKPEMGHNDLLIRIKKTAICGTDVHIYNWDEWSQKTIPVPMVVGHEYVGEVVDMGQEVRGFKVGDRVSGEGHITCGHCRNCRGGRTHLCRNTIGVGVNREGAFAEYLVIPAFNAFKIPEGISDDLASIFDPFGNAVHTALSFDLVGEDVLITGAGPIGIMAAAVAKHVGARHVVITDVNEYRLDLARKMGVTRAVNVANENLKDVMLELGMTEGFDVGLEMSGNPSAFNSMLQSMNHGGKIALLGIPPSDMGIDWNQVIFKGLVIKGIYGREMFETWYKMASLIQSGLDLTPIITHHYKIDDFEQGFDAMRSGLSGKVILDWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXB0</accession>
    <name>D0YXB0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Aspartate/glutamate leucyltransferase</fullName>
            <ecNumber evidence="4">2.3.2.29</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">bpt</name>
        <name evidence="7" type="ORF">VDA_001650</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>L-leucyl-tRNA(Leu) + N-terminal L-aspartyl-[protein] = H(+) + N-terminal L-leucyl-L-aspartyl-[protein] + tRNA(Leu)</text>
            <dbReference type="Rhea" id="RHEA:50420"/>
            <dbReference type="Rhea" id="RHEA-COMP:9613"/>
            <dbReference type="Rhea" id="RHEA-COMP:9622"/>
            <dbReference type="Rhea" id="RHEA-COMP:12669"/>
            <dbReference type="Rhea" id="RHEA-COMP:12674"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:64720"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78494"/>
            <dbReference type="ChEBI" id="CHEBI:133042"/>
            <dbReference type="EC" id="2.3.2.29"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>L-leucyl-tRNA(Leu) + N-terminal L-glutamyl-[protein] = H(+) + N-terminal L-leucyl-L-glutamyl-[protein] + tRNA(Leu)</text>
            <dbReference type="Rhea" id="RHEA:50412"/>
            <dbReference type="Rhea" id="RHEA-COMP:9613"/>
            <dbReference type="Rhea" id="RHEA-COMP:9622"/>
            <dbReference type="Rhea" id="RHEA-COMP:12664"/>
            <dbReference type="Rhea" id="RHEA-COMP:12668"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:64721"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78494"/>
            <dbReference type="ChEBI" id="CHEBI:133041"/>
            <dbReference type="EC" id="2.3.2.29"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the R-transferase family. Bpt subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.29" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001650"/>
    <dbReference type="EnsemblBacteria" id="EEZ40623">
        <property type="protein sequence ID" value="EEZ40623"/>
        <property type="gene ID" value="VDA_001650"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2935">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004057">
        <property type="term" value="F:arginyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008914">
        <property type="term" value="F:leucyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071596">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process via the N-end rule pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00689">
        <property type="entry name" value="Bpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017138">
        <property type="entry name" value="Asp_Glu_LeuTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030700">
        <property type="entry name" value="N-end_Aminoacyl_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007472">
        <property type="entry name" value="N-end_Aminoacyl_Trfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007471">
        <property type="entry name" value="N-end_Aminoacyl_Trfase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21367">
        <property type="entry name" value="PTHR21367"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04377">
        <property type="entry name" value="ATE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04376">
        <property type="entry name" value="ATE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037208">
        <property type="entry name" value="ATE_pro_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ATE_N" evidence="5">
        <location>
            <begin position="11"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="ATE_C" evidence="6">
        <location>
            <begin position="102"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="227" mass="26805" checksum="C4EB34AB9197F521" modified="2010-01-19" version="1">MSLQIGLTPESQCNYLPDQQEQVGVVMEQPWHSPLGYQVLIASGYRRSGRAIYKPMCRACSACTPLRIDCAHFTPTKSQKRQQNQMRQLHWEFKATLDDNWFELYEKYINNRHSDGSMYPANKEQFFDFCTASWMDTWFLHVYENNQLIAIAVTDVFEDSLSAVYSFFEPEHAWSLGTLCVLFQIEFCRQSNRPWLYPGYQIDACKAMNYKIRFKPHQKLIDGYWQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-08-12" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXB7</accession>
    <name>D0YXB7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">Outer-membrane lipoprotein carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">lolA</name>
        <name evidence="10" type="ORF">VDA_001657</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 9">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the LolA family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298459.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001657"/>
    <dbReference type="EnsemblBacteria" id="EEZ40630">
        <property type="protein sequence ID" value="EEZ40630"/>
        <property type="gene ID" value="VDA_001657"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2834">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1933827at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044874">
        <property type="term" value="P:lipoprotein localization to outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042953">
        <property type="term" value="P:lipoprotein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16325">
        <property type="entry name" value="LolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00240">
        <property type="entry name" value="LolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029046">
        <property type="entry name" value="LolA/LolB/LppX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004564">
        <property type="entry name" value="OM_lipoprot_carrier_LolA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018323">
        <property type="entry name" value="OM_lipoprot_carrier_LolA_Pbac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35869">
        <property type="entry name" value="PTHR35869"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03548">
        <property type="entry name" value="LolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89392">
        <property type="entry name" value="SSF89392"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00547">
        <property type="entry name" value="lolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0143">Chaperone</keyword>
    <keyword evidence="10" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="7 9" id="KW-0574">Periplasm</keyword>
    <keyword evidence="8 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0732">Signal</keyword>
    <keyword evidence="5 9" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5009009103" description="Outer-membrane lipoprotein carrier protein" evidence="9">
        <location>
            <begin position="22"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ40630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="203" mass="22675" checksum="19FFB3FC7F85E647" modified="2010-01-19" version="1" precursor="true">MKKAVLGLLVAPLLFASNVWADAQQDLSARLDKVNAFTADFQQKVVSPDGETLVNGSGTVAVKRPNLFRWDTQKPDENLLVSDGKTVWYYNPFVEQVTAMWLKNATEQTPFVLLTRNSASDWSQYNVHQTADTFTLTPKDKTSSMGKFVLTVNKNGQVRNFTVVEQDGQKSSFTFNDFKTATPAAKLFTFVPPKGVEVDDQRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXK2</accession>
    <name>D0YXK2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Trimethylamine-N-oxide reductase</fullName>
            <ecNumber evidence="4">1.7.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">VDA_001716</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
            <dbReference type="ChEBI" id="CHEBI:60539"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.7.2.3" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298569.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001716"/>
    <dbReference type="EnsemblBacteria" id="EEZ40687">
        <property type="protein sequence ID" value="EEZ40687"/>
        <property type="gene ID" value="VDA_001716"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0243">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="88184at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043546">
        <property type="term" value="F:molybdopterin cofactor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050626">
        <property type="term" value="F:trimethylamine-N-oxide reductase (cytochrome c) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041460">
        <property type="entry name" value="Molybdopterin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006657">
        <property type="entry name" value="MoPterin_dinucl-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006656">
        <property type="entry name" value="Mopterin_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006655">
        <property type="entry name" value="Mopterin_OxRdtase_prok_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00384">
        <property type="entry name" value="Molybdopterin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18364">
        <property type="entry name" value="Molybdopterin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01568">
        <property type="entry name" value="Molydop_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="SSF50692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00932">
        <property type="entry name" value="MOLYBDOPTERIN_PROK_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-0574">Periplasm</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Molybdopterin_N" evidence="12">
        <location>
            <begin position="40"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="Molybdopterin" evidence="10">
        <location>
            <begin position="86"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="domain" description="Molydop_binding" evidence="11">
        <location>
            <begin position="656"/>
            <end position="769"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF18364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ40687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="880" mass="97290" checksum="22ADF23236EDB886" modified="2010-01-19" version="1">MSLSRRNFLKGSVATAIAANGLTLFPAGKIFASDTQVIPSATHYGPFNAVVKNGKLIGVQPVNDIDPFPTEMLTKGIISRTFDDTRIKYPMVRKSLVEDPLGDHNPHLRGKEPFVRVSWDTAIALTSYCIARTIEKHGNEAVFSSSYGGWSHAGLNRPQTLQGRFFNLIGGQSSCAGDYSAGASGVILPHVIGDMEVYSPQTAWKVIEENTELVLFVGCDPWKTNRIEFRVADHSMQKHWEAFKEKGVKFISINPQKTQTDKALGSDMINIRPNTDTALFSAMSYYLVKNNKHDQAYIDKYTVGFDKYLDYLNGTTDGTEKTPEWAAEITGIPAEQITALADLCMSKRTQIAAGWALQRADHGEMIHWAIINFASIMGKIGKPGQGAGFSFHYGNGGTAQSGKRMPIGLSQGRNPVTKICPVVMISDMLNNPGKAYTRDGSNLTLPNAKLIYNAGNNLLSHQQDTNELIQALNNNIDTVICQDAWWCASAKYADIVLPATTTLERDDITSGGTYSNNKIYAMRKVIEPVGESLDDYEIFSRLAFMFNVHDKYTEGKTYFQHIKSSYEASDATEDFDTFWKNGVTHLSTPEEANNWTRHGDFYKDPEAHPLHTKSGKIELFCETVASFKAEGCPGMPQWIPPFEWLGNAKEGQVHVLSPHPWMRLHSQMANADVNSYESVQGRQMVLMNKEDAAAHGIKDGDLVEVYNERGALIGGAKLTDEAMRGVIYIHEGAWLQLDSKGRCNSGSINMLTSSKPCSGLSDATSANTCLAYFKKCTDPESPNEAYQPPKIVKTEAQVDLWALQLGKRIKAVAAAEGPEQSPGEKMYYSSCTLCHAAPHPSDFTYKQWKGITNSMFPRAGLNEKDRKLVLDFLKEHAKKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXS0</accession>
    <name>D0YXS0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Dihydroorotate dehydrogenase (quinone)</fullName>
            <ecNumber evidence="11">1.3.5.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">DHOdehase</fullName>
            <shortName evidence="11">DHOD</shortName>
            <shortName evidence="11">DHODase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Dihydroorotate oxidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">pyrD</name>
        <name evidence="13" type="ORF">VDA_002083</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 11">Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>(S)-dihydroorotate + a quinone = a quinol + orotate</text>
            <dbReference type="Rhea" id="RHEA:30187"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
            <dbReference type="ChEBI" id="CHEBI:30864"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.3.5.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
        <text evidence="11">Binds 1 FMN per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 11">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; orotate from (S)-dihydroorotate (quinone route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 11">Cell membrane</location>
            <topology evidence="3 11">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 11">Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.3.5.2" evidence="11"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002083"/>
    <dbReference type="EnsemblBacteria" id="EEZ41051">
        <property type="protein sequence ID" value="EEZ41051"/>
        <property type="gene ID" value="VDA_002083"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0167">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00946"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004152">
        <property type="term" value="F:dihydroorotate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd04738">
        <property type="entry name" value="DHOD_2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00225">
        <property type="entry name" value="DHO_dh_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005720">
        <property type="entry name" value="Dihydroorotate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012135">
        <property type="entry name" value="Dihydroorotate_DH_1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005719">
        <property type="entry name" value="Dihydroorotate_DH_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001295">
        <property type="entry name" value="Dihydroorotate_DH_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01180">
        <property type="entry name" value="DHO_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000164">
        <property type="entry name" value="DHO_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01036">
        <property type="entry name" value="pyrD_sub2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00911">
        <property type="entry name" value="DHODEHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00912">
        <property type="entry name" value="DHODEHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7 11" id="KW-0288">FMN</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 11 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8 11" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHO_dh" evidence="12">
        <location>
            <begin position="25"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="11">
        <location>
            <begin position="89"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="11">
        <location>
            <begin position="224"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="11">
        <location>
            <position position="153"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="40"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="150"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="223"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="275"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="296"/>
            <end position="297"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ41051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="315" mass="34196" checksum="9E9B93914D2CBA91" modified="2010-01-19" version="1">MQNFSRFTGTPLDLFYRQSIPDHPVEVMGLTFKNPVGLAAGLDKNGECIDAFGAMGFGFVEVGTVTPRPQPGNDKPRLFRLIPAEGIINRFGFNNLGVDNLVENVKKANYDGIIGINIGKNKDTPVENGAEDYLICMDKVYPYAGYIAINISSPNTPGLRTLQYGEMLDDLLSQLKAKQAELAELHGKYVPLALKIAPDLDDHEIEQICDSLLRNKIDGVIGTNTTLDRTLVEGMKHCDEMGGLSGRPLQNKSTAVIAKMAECLKGEIPIIGVGGIDSAISAREKMQAGASLVQIYTGFIYHGPKLVKDIVMGLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXS6</accession>
    <name>D0YXS6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002089</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41057">
        <property type="protein sequence ID" value="EEZ41057"/>
        <property type="gene ID" value="VDA_002089"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502ZVYH">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022090">
        <property type="entry name" value="DUF3634"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12321">
        <property type="entry name" value="DUF3634"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="80" mass="9305" checksum="27B289BCBE8B9154" modified="2010-01-19" version="1">MRLKFKQGELVEEKGQIPNGFRQACKDIGHKMPFDGVVKVYKTRFQTKLVFSKQIPSKVKQRINNVFPHSMNTKKQGKRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXX5</accession>
    <name>D0YXX5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002138</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299521.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002138"/>
    <dbReference type="EnsemblBacteria" id="EEZ41106">
        <property type="protein sequence ID" value="EEZ41106"/>
        <property type="gene ID" value="VDA_002138"/>
    </dbReference>
    <dbReference type="GeneID" id="57341726"/>
    <dbReference type="eggNOG" id="COG3157">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1153621at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036624">
        <property type="entry name" value="Hcp1-lik_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008514">
        <property type="entry name" value="T6SS_Hcp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05638">
        <property type="entry name" value="T6SS_HCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141452">
        <property type="entry name" value="SSF141452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03344">
        <property type="entry name" value="VI_effect_Hcp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="173" mass="19228" checksum="4EAC1FC50C574E00" modified="2010-01-19" version="1">MPTPCYISIQGKTQGNITSGAFTANSVGNIFVEGHEDQMLVQEFKHIVTVPTDPQSGQPSGQRVHKPFKFTVALNKAVPLLYNALASGEMLPTVELKWYRTSIQGKQEHFFTTTLTDATIVDINNQMPHCQDPSKADYTQLIEVSMAYRKINWDHKISGTSGSDDWRAPLEAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY11</accession>
    <name>D0YY11_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Guanosine-inosine kinase</fullName>
            <ecNumber evidence="1">2.7.1.73</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">gsk</name>
        <name evidence="3" type="ORF">VDA_002174</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the phosphorylation of guanosine and inosine to GMP and IMP, respectively.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + guanosine = ADP + GMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:27710"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16750"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.73"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + inosine = ADP + H(+) + IMP</text>
            <dbReference type="Rhea" id="RHEA:21140"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17596"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.73"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; GMP biosynthesis via salvage pathway.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; IMP biosynthesis via salvage pathway; IMP from inosine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the carbohydrate kinase PfkB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.73" evidence="1"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299590.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002174"/>
    <dbReference type="EnsemblBacteria" id="EEZ41142">
        <property type="protein sequence ID" value="EEZ41142"/>
        <property type="gene ID" value="VDA_002174"/>
    </dbReference>
    <dbReference type="GeneID" id="57341685"/>
    <dbReference type="eggNOG" id="COG0524">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1604782at2"/>
    <dbReference type="UniPathway" id="UPA00591">
        <property type="reaction ID" value="UER00647"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00909"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106366">
        <property type="term" value="F:guanosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008906">
        <property type="term" value="F:inosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02246">
        <property type="entry name" value="Gua_Ino_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046405">
        <property type="entry name" value="IngK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1" id="KW-0660">Purine salvage</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="2">
        <location>
            <begin position="137"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="284"/>
            <end position="289"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="357"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="402"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="434" mass="49045" checksum="CD591F79EB587678" modified="2010-01-19" version="1">MKFPGQRKSKHYFPVNARDPLVAQIQQENPLARTHLVGVGQTIVDIEARVDDDFLQRHALSKGHSLVLDEDKAELLYKELKERNLISHEYPGDTIGNTLHNYSVLADDKSILLGVMSKDLKIGSYAYRYLCNTSCRMDLDYLQPVDGPIGRCYTLISEDGERTFAINEGDMNQLRPDNIPEKAFKKASALVLSSYLVRGKPNDPMKDSALKAIEYAKKYDVPVVLTLGTKYVIEDRREWWIDFLKEHVTCVAMNEEEGEALTGEKDPLLAADKALEWVDLVLCTAGPVGLYMAGYTDDELKRESSLPLLPGKIPEFNKYEFSRPMKKADCENPIRVYSHIAPYLGGPVEIKNTNGAGDAALSALLHDMSANRYHKFNVPNSAKHNGNFLSYSSFSQICQYSNRASYEVLIQHAPRLSRGLPEREDCLEEAYWER</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY76</accession>
    <name>D0YY76_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Arginine ABC transporter permease protein ArtM</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_002239</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002239"/>
    <dbReference type="EnsemblBacteria" id="EEZ41207">
        <property type="protein sequence ID" value="EEZ41207"/>
        <property type="gene ID" value="VDA_002239"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4160">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010065">
        <property type="entry name" value="AA_ABC_transptr_permease_3TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043429">
        <property type="entry name" value="ArtM/GltK/GlnP/TcyL/YhdX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30614">
        <property type="entry name" value="PTHR30614"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01726">
        <property type="entry name" value="HEQRo_perm_3TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="84"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="156"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="189"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="8">
        <location>
            <begin position="14"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="224" mass="24709" checksum="8353B9A98398450B" modified="2010-01-19" version="1">MMNEHYFWQLVEGLGTSLQLTVVSLAVGCTLALLMTLSLILKTPVISQLNKGIIILFTGTPLLVQIFLVYYGPGQFEAVRNSFVWHWLSQPWFCAMLALALNTAAYSTQLFKGAFNAIPSGQWLACRALGMNTRQSLGVLLPFAIRRAVPAYSNEVILVFKGTSLASTITIMDLMGYAQRINGQTYDTLTVFGIAGAMYLLVNGILTLIFRQIEKRALAFEVAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-02-10" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY94</accession>
    <name>D0YY94_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Alanine dehydrogenase</fullName>
            <ecNumber evidence="2">1.4.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_002257</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AlaDH/PNT family.</text>
    </comment>
    <dbReference type="EC" id="1.4.1.1" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002257"/>
    <dbReference type="EnsemblBacteria" id="EEZ41225">
        <property type="protein sequence ID" value="EEZ41225"/>
        <property type="gene ID" value="VDA_002257"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0686">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000286">
        <property type="term" value="F:alanine dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042853">
        <property type="term" value="P:L-alanine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05305">
        <property type="entry name" value="L-AlaDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008141">
        <property type="entry name" value="Ala_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007886">
        <property type="entry name" value="AlaDH/PNT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007698">
        <property type="entry name" value="AlaDH/PNT_NAD(H)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42795">
        <property type="entry name" value="PTHR42795"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01262">
        <property type="entry name" value="AlaDh_PNT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05222">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01002">
        <property type="entry name" value="AlaDh_PNT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01003">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AlaDh_PNT_N" evidence="5">
        <location>
            <begin position="4"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="AlaDh_PNT_C" evidence="4">
        <location>
            <begin position="149"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="266" mass="28215" checksum="EC52DFC2B8C327A4" modified="2010-01-19" version="1">MIIGVPKEIKVHEYRVGMIPASVVEAVAHGHKVYVETLAGQGIGFSDQDYVDAGALILPSAAAVFAEADMIVKVKEPQAIERAMLREGQILFTYLHLAPDPEQTHDLINSKAICIAYETVTDDKGRLPLLAPMSEVAGRMSIQAGALALEKSHGGKGLLLAGVPGVEPAKVVILGGGVVGANAAQMAIGLRANVVILDRNLDVLRQLDQQFSGQVQCIYSTKESVEKHVLDADLVVGCVLVAGAAAPKLVTADMIKKMQPARPLWM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY97</accession>
    <name>D0YY97_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299745.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002260"/>
    <dbReference type="EnsemblBacteria" id="EEZ41228">
        <property type="protein sequence ID" value="EEZ41228"/>
        <property type="gene ID" value="VDA_002260"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="626204at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="246"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="286"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="312"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="349"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="375"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="410" mass="44434" checksum="DA0F5C17DE7F9F67" modified="2010-01-19" version="1">MFSTIPANVRQYMLVTFNYWNFTVTDGALRMLVVLYFHQLGYSPLEIASLFLFYEFFGVITNLIGGWLGAKLGLNRTMNIGLALQIIALSMLAVPTDMLTVIWVMLAQAISGIAKDLNKMSAKSAIKTLVPSGEQGALYKWIAILTGSKNALKGAGFFLGGFLLSWLGFSGAVIAMAGVLLAVFILSLCYLKGDLGKAKQKVKFSQIFSKSPSVNILSAARMFLFGARDVWFVIALPIYLGQVFGWDHLWVGGFIALWIIGYGIVQTLAPKVTGKAQGKTPDGRAAMGWAGLLATVTALIALLVTFNLSPQITIALGLMIFGAIFAVNSSLHSYLIVSYAKEDGVSLDVGFYYMANAMGRLMGTLLSGWIYQTQGFVACLWVSVVFLVLTTIISVWLPKQSVSTSHTSIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYC5</accession>
    <name>D0YYC5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">TPR repeat containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_002288</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299792.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002288"/>
    <dbReference type="EnsemblBacteria" id="EEZ41256">
        <property type="protein sequence ID" value="EEZ41256"/>
        <property type="gene ID" value="VDA_002288"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029228">
        <property type="entry name" value="Alkyl_sulf_dimr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14863">
        <property type="entry name" value="Alkyl_sulf_dimr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019237" evidence="2">
        <location>
            <begin position="21"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="Alkyl_sulf_dimr" evidence="3">
        <location>
            <begin position="188"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="284" mass="33080" checksum="357060A3232047B9" modified="2010-01-19" version="1">MVRNRFWLVIFLLFSCQVFADTTSEVPYSQKSIYEKPLMERYVLDELKSLRTDQQDLERRLIKEITDRELTVADKSMNYANVTVTYFFYIIAGVASLIALVGWQSLKEIKTNTKEMADKQLKEITEQYEMKFRALERDLKRKTRIITENNREIEIINEVHNLWLRAQNAQTPEQQMEIYDEILKIRPGDLEALTYKADAAMASKEYRWALSLCNRVLEVDDTNAQALYQRACAYACLGAEEQAISDLERAINESASLRDSAADEPDFENLHGNERFEALLIFAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYF4</accession>
    <name>D0YYF4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002317</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002317"/>
    <dbReference type="EnsemblBacteria" id="EEZ41285">
        <property type="protein sequence ID" value="EEZ41285"/>
        <property type="gene ID" value="VDA_002317"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5032S0P">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1708262at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021367">
        <property type="entry name" value="DUF2982"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11201">
        <property type="entry name" value="DUF2982"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="219" mass="25179" checksum="974BF3E469423274" modified="2010-01-19" version="1">MRTTYICSPKLSSYSHMTIIAVALIIAFSALIYFVPGINVSLIALLFLAIFTLIALYSLTHSPSVIFSLTFMHMQFHSKTGGWLIQWNNVRAVGIATIETQGWHHKIPWIGIRLKNYDQFLNSICLRTASKIMTEQRDLLLIAYKQIQSPQHELEDILFDDSVYIMEDGKELTGLLATLANRMRYNREYLGYDFFISDDLVDRPIDEFIGLIRRYMAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYG4</accession>
    <name>D0YYG4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">Trimethylamine-N-oxide reductase</fullName>
            <shortName evidence="11">TMAO reductase</shortName>
            <ecNumber evidence="4 11">1.7.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">torA</name>
        <name evidence="15" type="ORF">VDA_002327</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 11">Reduces trimethylamine-N-oxide (TMAO) into trimethylamine; an anaerobic reaction coupled to energy-yielding reactions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>2 Fe(III)-[cytochrome c] + H2O + trimethylamine = 2 Fe(II)-[cytochrome c] + 3 H(+) + trimethylamine N-oxide</text>
            <dbReference type="Rhea" id="RHEA:24236"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15724"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:58389"/>
            <dbReference type="EC" id="1.7.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
            <dbReference type="ChEBI" id="CHEBI:60539"/>
        </cofactor>
        <text evidence="11">Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 11">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="11">Exported by the Tat system.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.7.2.3" evidence="4 11"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299880.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002327"/>
    <dbReference type="EnsemblBacteria" id="EEZ41295">
        <property type="protein sequence ID" value="EEZ41295"/>
        <property type="gene ID" value="VDA_002327"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0243">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="88184at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030151">
        <property type="term" value="F:molybdenum ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043546">
        <property type="term" value="F:molybdopterin cofactor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050626">
        <property type="term" value="F:trimethylamine-N-oxide reductase (cytochrome c) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02793">
        <property type="entry name" value="MopB_CT_DMSOR-BSOR-TMAOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041954">
        <property type="entry name" value="CT_DMSOR/BSOR/TMAOR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041460">
        <property type="entry name" value="Molybdopterin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006657">
        <property type="entry name" value="MoPterin_dinucl-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006656">
        <property type="entry name" value="Mopterin_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006655">
        <property type="entry name" value="Mopterin_OxRdtase_prok_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019546">
        <property type="entry name" value="TAT_signal_bac_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011887">
        <property type="entry name" value="TorA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00384">
        <property type="entry name" value="Molybdopterin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18364">
        <property type="entry name" value="Molybdopterin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01568">
        <property type="entry name" value="Molydop_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="SSF50692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01409">
        <property type="entry name" value="TAT_signal_seq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02164">
        <property type="entry name" value="torA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00490">
        <property type="entry name" value="MOLYBDOPTERIN_PROK_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00932">
        <property type="entry name" value="MOLYBDOPTERIN_PROK_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 11" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="9 11 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8 11" id="KW-0574">Periplasm</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Molybdopterin_N" evidence="14">
        <location>
            <begin position="49"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="Molybdopterin" evidence="12">
        <location>
            <begin position="93"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="domain" description="Molydop_binding" evidence="13">
        <location>
            <begin position="682"/>
            <end position="802"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU368014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF18364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEZ41295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="826" mass="93577" checksum="217347CB9598776A" modified="2010-01-19" version="1">MSLTRRKFLQGVATTSAVTVIGPSLLTQLAHATVQDGAPAQEPGTWKVSGSHWGAFRARIYNGQVMEIKPLEQDKHPTDMLNGIIGLIYSPSRIRYPLVRLDWLRKNKYSGETRGNNRFVRVTWDEALDLFFQELHRVQKDYGPWALHAGQTGWRETGQFHSCTSHMQRAVGMYGNFIKKVGDYSTGAGQTILPYVIGSTEVYAQATTWPHILEHCDTLIWWSNDPMKNSQVGWQCETHDCYDYYAQLKEKIAKKEIKVISVDPVISQTQNYLSCEHQYVNPQTDVAFMLALAYTLYDEKLYDKSFMETYTLGFEDFLPYLLGKGEDKTAKTPEWAEPICGIKADEIQKFARMLAKGRTMMIFGWSIQRQLHGEQPYWMAVVLASMLGKIGLPGGGISFSHQYSGVGTPYSNAAGPGGFPRNVDEGQVPVWNNTDFKGYSSIIPVARWIDAIMEPGKKIQYNGSQVVLPDIKMMVFSGCNPWNHHQDRNRMKEAFRKLQTVVNIDYTWTPTCRFSDIVLPACTQFERNDIDQFGTYSTAGILAMHKLVDPLFQSKTDFQIFTELCERFGKSKEYTRGMTEMEWVKQLYNDCRAANKDKYPMPEFNKFWQQGLAPFKTDQSMVSHAAFREDPEINPLGTPSGFIEIYSRKIACYKYPYCQGHPMWFEKNERSHGGPKSDKYPLWLQSCHPPKRLHSQMCDSEKFRETYAVKGREPVHLNPDDAKARGIKDGDIVRVFNDRGQLLAGAKVSGDYPPGVIRITEGAWFGPINNDIGALDTYGDPNTLTQDIGTSELAQATSANTVVVQVEKFKGEVPPVTSFSGPIYVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYJ3</accession>
    <name>D0YYJ3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NADH dehydrogenase</fullName>
            <ecNumber evidence="4">1.6.99.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_002356</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NADH dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.6.99.3" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299944.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002356"/>
    <dbReference type="EnsemblBacteria" id="EEZ41324">
        <property type="protein sequence ID" value="EEZ41324"/>
        <property type="gene ID" value="VDA_002356"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1252">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="403436at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003954">
        <property type="term" value="F:NADH dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006116">
        <property type="term" value="P:NADH oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045024">
        <property type="entry name" value="NDH-2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43706">
        <property type="entry name" value="PTHR43706"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="3">
        <location>
            <begin position="3"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="407" mass="44738" checksum="E369C97A2D3E475E" modified="2010-01-19" version="1">MSRIVVVGGGAAGLELSTLLTKSVRKEDEIVLVEPETHHYWKPRLHEIAAGTFDSELDTVCYFTHGAKHGYQHYQGAMKDIDRVNKTITVQRPDGTESGINYDYLVIAIGAVSNDFRTTGAQDHCLFLDSASQARQAWNQVSQLLRSGDEHAINIVGAGATGVELAAELARVSQKLQRYNAAKLHINLIEAAERVLPNSPIAMSSKVLKELQRNNVNVLLNTRIAEVTDMGMRTSDEQFLHADVQFWAAGVKAPDWLNGMGGLQHNPLNQIKVRANLTTTEDPNVFALGDCASIPQADGSFVPPKAQAANRAAVHLAKSLGDMLKRGYPPTDFEFKDSGMVVAVGHHFAVGSFAPGSKLEGKLVLQGRLIRRLYDTIFRLHQRTVTGMFTVSRLMITKRLKCVFMPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYR7</accession>
    <name>D0YYR7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">VDA_002430</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002430"/>
    <dbReference type="EnsemblBacteria" id="EEZ41398">
        <property type="protein sequence ID" value="EEZ41398"/>
        <property type="gene ID" value="VDA_002430"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004721">
        <property type="term" value="F:phosphoprotein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="152"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="11">
        <location>
            <begin position="248"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="12">
        <location>
            <begin position="489"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="214"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="8">
        <location>
            <position position="538"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ41398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="615" mass="69505" checksum="347C3C45034D405B" modified="2010-01-19" version="1">MKQIGRLPLWGKYLLVIVSLTMVMCFVFGEILRISETKFIEEKIQGQLEQYSNIIVSATKQDLLEQDTQRLENTVLTITHNIPSLAHLCFYNRDNQKVFQWGSADDHHDDHFHYEITKDVVVNNGYIGKVEIALKNQVPEEIIAHHVAYIRIILAASLLLLGCLCYFVSQYLIINPIARINNKILSLKEMYPKLNQVKENQSEMQRLNSSVFILKQVLEKQREKELLLQEAQHESEEANRIKTEFIATMSHEIRTPMNVILGSLEVLNEEDLSPKSKRFAEISQSAAHLLLNQLNDVLDFARLESGKVALSQGEFSPYKLVRSIEDIFRNQAEQKGVKFHVDIGFSPELFMVSDEGKISQILTNIVGNALKFTSSGSITIRARWHETEQLIFTISDTGIGIDKDKIASILQPFVQSDASFSRRYGGAGMGLAITSALVELLCGQLEIDSQVAKGTQFTVRLPIAKSYFKQQKQSGSSKHDDWTLLHGKKILLVEDSISNQLIAKTILEKNGFVVETALNGREAIEQVQQVKVDAVLMDLQMPELNGLEASLAIRRLGGIYTSLPIIAMTANASDKDREECHQAGMDDYLTKPINKQHMLEVLRIWLTTQSIPEIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYZ7</accession>
    <name>D0YYZ7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Flavodoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_002510</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Low-potential electron donor to a number of redox enzymes.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the flavodoxin family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300225.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41478">
        <property type="protein sequence ID" value="EEZ41478"/>
        <property type="gene ID" value="VDA_002510"/>
    </dbReference>
    <dbReference type="GeneID" id="57341262"/>
    <dbReference type="eggNOG" id="COG0716">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1961680at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001226">
        <property type="entry name" value="Flavodoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010086">
        <property type="entry name" value="Flavodoxin_lc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038996">
        <property type="entry name" value="FldA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01752">
        <property type="entry name" value="flav_long"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00201">
        <property type="entry name" value="FLAVODOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0249">Electron transport</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4 5" id="KW-0288">FMN</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="6">
        <location>
            <begin position="4"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR038996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="175" mass="19720" checksum="4D70A128E17E815D" modified="2010-01-19" version="1">MASVGLFFGSDTGNTEAVAKMIQKQLSDKLVEVKDIAKSSKEDIDNFDLLILGIPTWYYGEAQCDWDDFFPELEQIDFSTKLVAIFGCGDQEDYAEYFCDAMGTIREIVEGRGATVVGNFSTEGFEFEASKALVDDNHFVGLCVDEDRQPELTEQRVTQWVNQLMDEMCLSELMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ23</accession>
    <name>D0YZ23_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">EAL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002536</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300277.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002536"/>
    <dbReference type="EnsemblBacteria" id="EEZ41504">
        <property type="protein sequence ID" value="EEZ41504"/>
        <property type="gene ID" value="VDA_002536"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2200">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="206"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="2">
        <location>
            <begin position="235"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="510" mass="58633" checksum="DF9EBA39BB569E58" modified="2010-01-19" version="1">MSFSLKKFFLIALLSIFISSSLVVTYLSYRSEQISFEVNKSLNSSFTQLKKDVLLIQEVHNHSQDLNKLVTLILASRSLRSVAYIQDDHYVYSDRQLHLNQEISSSLQQKIKTEALPFLYRKQSSLNNIEELHFVIKGKNGFYQLFLNARYMDDWLDNADLTLNGYVVNNHNQPIINQPQKLLIKAVYQSPQYPFKVVIGEPTQDVIILIAMGAAFIFAFILLGLLFAKHLYNNNFSFRVDIERAIRAKEFIAYYQPIVSNKNLQCSGAELLCRWHHKKKRILAPNHFITKVEESGQIKAITLQLLNQLVKDKIQLCKHNPDFYISINFTLAMLRDEAYMAEVMALIKKNTSLQSGLVFELTERENTTCAMKELNTVMTQFRQIGVRWALDDFGTGYSSLSSVRSLNFDIIKIDKLFVLTADTDAITSSILKNIAYLGKGLNCKMVAEGVETQTQFNKLLGLNIDYSQGYLFSKPMAIKDFLLFQHSFDHRAYICQQPDLEINYQPIVVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ66</accession>
    <name>D0YZ66_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002579</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41547">
        <property type="protein sequence ID" value="EEZ41547"/>
        <property type="gene ID" value="VDA_002579"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021244">
        <property type="entry name" value="DUF2802"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10975">
        <property type="entry name" value="DUF2802"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="38" mass="4455" checksum="A2878B1D23A31B48" modified="2010-01-19" version="1">MAELGADLHELMRECDLPKAEAELLMRLQQTRSQKRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ78</accession>
    <name>D0YZ78_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 13">Flagellar biosynthetic protein FlhB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">flhB</name>
        <name evidence="15" type="ORF">VDA_002591</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 13">Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the type III secretion exporter family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300415.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002591"/>
    <dbReference type="MEROPS" id="N06.A01"/>
    <dbReference type="EnsemblBacteria" id="EEZ41559">
        <property type="protein sequence ID" value="EEZ41559"/>
        <property type="gene ID" value="VDA_002591"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1377">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1424100at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044780">
        <property type="term" value="P:bacterial-type flagellum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1690.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006136">
        <property type="entry name" value="FlhB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006135">
        <property type="entry name" value="T3SS_substrate_exporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029025">
        <property type="entry name" value="T3SS_substrate_exporter_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30531">
        <property type="entry name" value="PTHR30531"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01312">
        <property type="entry name" value="Bac_export_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00950">
        <property type="entry name" value="TYPE3IMSPROT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160544">
        <property type="entry name" value="SSF160544"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00328">
        <property type="entry name" value="flhB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-1005">Bacterial flagellum biogenesis</keyword>
    <keyword evidence="11 13" id="KW-1006">Bacterial flagellum protein export</keyword>
    <keyword evidence="5 13" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="15" id="KW-0966">Cell projection</keyword>
    <keyword evidence="15" id="KW-0969">Cilium</keyword>
    <keyword evidence="15" id="KW-0282">Flagellum</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 13" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 13" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="33"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="96"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="138"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="183"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="357"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU364091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEZ41559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="376" mass="42059" checksum="39E0EA18A27C142A" modified="2010-01-19" version="1">MADSDDQERTEDATPRRRQQAQEKGQVPRSRELASVAVLIAGAVGLMWFGGSLGQALAAVMSRLFSLTREEVFDLGAMSTVISEVIWGIAAPLTLVLVFLFVAAFIGAAGLGGVRFSSEAAMPKLSKMNPLSGFKRMFGMQSWVELIKSILKVGLVSGVAYYLMYDSLDDFFQLAQESYPNNIYHALSTLLHFILLISCSLLVVVAIDVPFQIYQFNQQLKMTKQEIKDEYKETEGKPEVKGRIRMLQREMAQRRMMADVPQADVIITNPEHYSVALRYDPKLDSAPVVIAKGVDHTAFKIREIAKEHNIDIVPVPPLARAIYHTTELEQQIPDGLFIAVAQVLAYVFQLKQYRRGKGQKPKLSPDSEQIPTELRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ85</accession>
    <name>D0YZ85_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Flagellar assembly protein FliH</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_002598</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Needed for flagellar regrowth and assembly.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FliH family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300435.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002598"/>
    <dbReference type="EnsemblBacteria" id="EEZ41566">
        <property type="protein sequence ID" value="EEZ41566"/>
        <property type="gene ID" value="VDA_002598"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1317">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1285795at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009288">
        <property type="term" value="C:bacterial-type flagellum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003774">
        <property type="term" value="F:cytoskeletal motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000563">
        <property type="entry name" value="Flag_FliH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018035">
        <property type="entry name" value="Flagellar_FliH/T3SS_HrpE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02108">
        <property type="entry name" value="FliH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01003">
        <property type="entry name" value="FLGFLIH"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1006">Bacterial flagellum protein export</keyword>
    <keyword evidence="10" id="KW-0966">Cell projection</keyword>
    <keyword evidence="10" id="KW-0969">Cilium</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0282">Flagellum</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="FliH" evidence="9">
        <location>
            <begin position="128"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="84"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="95"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ41566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="271" mass="30495" checksum="8E7A0682243A4495" modified="2010-01-19" version="1">MDNDRRRGFVRINSDQAEVLERWCFPDYSDELPHQHDNALNYELQRQVPEPEPHHAPEEDSPPPLTAADLDEIHQSAYDDGFAEGRKAGYDEGFSQGQQDGQQLGQQQGVEQGLAQGLEQAQTHIAAQVDALALVMDNLATPIAVMNEEVRAQVLQLAISLTRELIRVEVQTNSQVILQTINDVIASLPVVERETHIALNPEDHQQVLEAYGSENLAERKWKLTIEPALQRGDVQVRAGDASVDYRMEQRIRHLLQQFVGNNNLDQESIAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZJ1</accession>
    <name>D0YZJ1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Dual-specificity RNA methyltransferase RlmN</fullName>
            <ecNumber evidence="14">2.1.1.192</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">23S rRNA (adenine(2503)-C(2))-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">23S rRNA m2A2503 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">Ribosomal RNA large subunit methyltransferase N</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">tRNA (adenine(37)-C(2))-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">tRNA m2A37 methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">rlmN</name>
        <name evidence="16" type="ORF">VDA_002704</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>adenosine(2503) in 23S rRNA + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = 2-methyladenosine(2503) in 23S rRNA + 5'-deoxyadenosine + L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin] + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42916"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10152"/>
            <dbReference type="Rhea" id="RHEA-COMP:10282"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74497"/>
            <dbReference type="EC" id="2.1.1.192"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>adenosine(37) in tRNA + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = 2-methyladenosine(37) in tRNA + 5'-deoxyadenosine + L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin] + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:43332"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10162"/>
            <dbReference type="Rhea" id="RHEA-COMP:10485"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74497"/>
            <dbReference type="EC" id="2.1.1.192"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="14">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="14">Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the radical SAM superfamily. RlmN family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.192" evidence="14"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300750.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002704"/>
    <dbReference type="EnsemblBacteria" id="EEZ41672">
        <property type="protein sequence ID" value="EEZ41672"/>
        <property type="gene ID" value="VDA_002704"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0820">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1111428at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070040">
        <property type="term" value="F:rRNA (adenine-C2-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002935">
        <property type="term" value="F:tRNA (adenine-C2-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01849">
        <property type="entry name" value="RNA_methyltr_RlmN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040072">
        <property type="entry name" value="Methyltransferase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027492">
        <property type="entry name" value="RNA_MTrfase_RlmN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004383">
        <property type="entry name" value="rRNA_lsu_MTrfase_RlmN/Cfr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30544">
        <property type="entry name" value="PTHR30544"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006004">
        <property type="entry name" value="CHP00048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00275">
        <property type="entry name" value="adenosine_C2_methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00048">
        <property type="entry name" value="rRNA_mod_RlmN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 14" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4 14" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13 14" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="11 14" id="KW-0408">Iron</keyword>
    <keyword evidence="12 14" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="10 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 14 16" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 14" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="8 14" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="7 14 16" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 14" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Radical SAM core" evidence="15">
        <location>
            <begin position="100"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="14">
        <location>
            <begin position="168"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="14">
        <location>
            <begin position="222"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="14">
        <location>
            <position position="94"/>
        </location>
    </feature>
    <feature type="active site" description="S-methylcysteine intermediate" evidence="14">
        <location>
            <position position="344"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="200"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="301"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="(transient)" evidence="14">
        <location>
            <begin position="107"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EEZ41672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="372" mass="41952" checksum="9ACDD2A64B784F99" modified="2010-01-19" version="1">MTAVKVNLLDFDRKGMRKFFAEELEEKAFRADQIMKWIYHFGCDDFDQMTNINKKLREKLKVIAEIKAPTVSAAQYSKDGTIKWAMRVGDQDVETVYIPDDDRATLCVSSQVGCALECKFCSTAQQGFNRNLCVSEIIGQVWRAAKEIGVQKETGRRPITNVVMMGMGEPLLNMKNLLPALEIMLDDLGFGLSKRRVTVSTSGVVSGLEQMIGNIDVALAISLHAPTDELRSQIMPINNRWNIEEFLDAVRRYVNSTNANRGRVTVEYVLLDHINDDMEHARQLAKVLKDTPAKINLIPFNPYPGSPYNKPSNSRIDRFMKTLMEYDITVTVRKTRGDDIDAACGQLVGDVIDRTKRTQAKQQGEQIPVKAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZL3</accession>
    <name>D0YZL3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Alkyl hydroperoxide reductase C</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Peroxiredoxin</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Thioredoxin peroxidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_002726</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300830.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002726"/>
    <dbReference type="EnsemblBacteria" id="EEZ41694">
        <property type="protein sequence ID" value="EEZ41694"/>
        <property type="gene ID" value="VDA_002726"/>
    </dbReference>
    <dbReference type="GeneID" id="57341001"/>
    <dbReference type="eggNOG" id="COG0450">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="892697at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051920">
        <property type="term" value="F:peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024706">
        <property type="entry name" value="Peroxiredoxin_AhpC-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019479">
        <property type="entry name" value="Peroxiredoxin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10417">
        <property type="entry name" value="1-cysPrx_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000239">
        <property type="entry name" value="AHPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="8">
        <location>
            <begin position="2"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine sulfenic acid (-SOH) intermediate" evidence="7">
        <location>
            <position position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00032077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000239-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="202" mass="22308" checksum="07B25564F8296354" modified="2010-01-19" version="1">MVLVGRQAPDFTAAAVLGNGEIVDNFNFAEFTKGKKAVVFFYPLDFTFVCPSELIAFDKRFEDFQAKGVEVIGVSIDSQFSHNAWRNTAVENGGIGQVKYPLVADVKHEICKAYDVEHPEAGVAFRGSFLIDEDGMVRHQVVNDLPLGRNIDEMLRMVDALNFHQKHGEVCPAQWEEGKAGMDASPKGVAAYLSEHTEDLGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZP5</accession>
    <name>D0YZP5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type 4 fimbrial biogenesis protein PilW</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002758</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300923.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002758"/>
    <dbReference type="EnsemblBacteria" id="EEZ41726">
        <property type="protein sequence ID" value="EEZ41726"/>
        <property type="gene ID" value="VDA_002758"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4966">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1934074at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016419">
        <property type="entry name" value="Prepilin_Pept-dep_B_prd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004525">
        <property type="entry name" value="Pilin_peptidase-dep_B_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="196" mass="21546" checksum="A2FA56FED0D06986" modified="2010-01-19" version="1">MKSAKGFSLIELLIASSVGLIAIGIVGSVFLSGYQAANKRSLELLLQQDVNDAFRLIKEDVLRAGYVSSGASSLKLSGASNVVYVNSDNNCLAYAYHSPDGRRYNEVMYNEQDRKLVYRSIDDEITALNACSLSRERSYSLIYDKQITVNQFDIENTPISSASATSQLLTIKLAAKIKSSAVSTTKSIQIKTRNWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZV2</accession>
    <name>D0YZV2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycogen debranching enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_002815</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 13 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301087.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002815"/>
    <dbReference type="EnsemblBacteria" id="EEZ41783">
        <property type="protein sequence ID" value="EEZ41783"/>
        <property type="gene ID" value="VDA_002815"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1523">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="99080at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004133">
        <property type="term" value="F:glycogen debranching enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005980">
        <property type="term" value="P:glycogen catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02856">
        <property type="entry name" value="E_set_GDE_Isoamylase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044505">
        <property type="entry name" value="GlgX_Isoamylase_N_E_set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004193">
        <property type="entry name" value="Glyco_hydro_13_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011837">
        <property type="entry name" value="Glycogen_debranch_GlgX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02922">
        <property type="entry name" value="CBM_48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02100">
        <property type="entry name" value="glgX_debranch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aamy" evidence="3">
        <location>
            <begin position="164"/>
            <end position="571"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="692" mass="79454" checksum="084399074480EEBC" modified="2010-01-19" version="1">MDIQQYKRIFSAIGEPYPLGATIKAKGVNFSLYSRDATKVELHLFESADAPTPFKSFTLDPIYHKRGHYWFTFVANITHGQIYAFTVDGPWQPEIGLRFNKNKVLLDPYSHAICMNHDYSRERARDFDSNMDCCMKSIVVDHSHFDWQNTDSPRHSLTDTIIYEMHVGGFTQHPSSNVTPSHRGTFAGIIDKISYLKQLGITAVELMPIQHFDLHDAPAGRENYWGYSPINFFALHSPYSSSKDPLAAINEFKTLVRELHKAGIEVILDVVFNHTAEGDENGPTFCFKGLQNDGYYLLDPKTHQYANYSGCGNTCNANYSVQRRMIIDALHYWVKEMHVDGFRFDLASVLARDSDGKPMKEPPLLWSIDSDPVLSGTKIIAEAWDAAGLYQVGSFIGDRWNEWNGKFRDDVRAFWRGDRNTVSRFSSRILGSPDIYSSQHHTPHRSVNFICAHDGFTLNDLVSYQDKHNWDNGEHNRDGDNHNISCNYGIEGPTDVAEIEAIRHRQCKNFLTTLYLSLGTPMLCMGDEVRRTQQGNNNAYCQNNELSWFDWQLVEKNADLLRFVQLLAQIRRAEPTIEWNMHRSLEEVLGNVGIEWHGVKPNQPDWSERSHSVALTVHHPLTQDELYVICNAYWDPLNFTLPKRDHSDWYILVNTGLEPPNDIYRMEKAPKYQDDNIIASGRSMIVMVEKKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0F4</accession>
    <name>D0Z0F4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glucose-6-phosphate isomerase</fullName>
            <shortName evidence="7">GPI</shortName>
            <ecNumber evidence="7">5.3.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Phosphoglucose isomerase</fullName>
            <shortName evidence="7">PGI</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Phosphohexose isomerase</fullName>
            <shortName evidence="7">PHI</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pgi</name>
        <name evidence="9" type="ORF">VDA_003018</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7 8">
            <text>alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:11816"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:58225"/>
            <dbReference type="EC" id="5.3.1.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 7 8">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7 8">Belongs to the GPI family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.9" evidence="7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301578.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003018"/>
    <dbReference type="EnsemblBacteria" id="EEZ41985">
        <property type="protein sequence ID" value="EEZ41985"/>
        <property type="gene ID" value="VDA_003018"/>
    </dbReference>
    <dbReference type="GeneID" id="57340530"/>
    <dbReference type="eggNOG" id="COG0166">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="417261at2"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00181"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004347">
        <property type="term" value="F:glucose-6-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd05015">
        <property type="entry name" value="SIS_PGI_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05016">
        <property type="entry name" value="SIS_PGI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00473">
        <property type="entry name" value="G6P_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001672">
        <property type="entry name" value="G6P_Isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023096">
        <property type="entry name" value="G6P_Isomerase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018189">
        <property type="entry name" value="Phosphoglucose_isomerase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035476">
        <property type="entry name" value="SIS_PGI_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035482">
        <property type="entry name" value="SIS_PGI_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11469">
        <property type="entry name" value="PTHR11469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00342">
        <property type="entry name" value="PGI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00662">
        <property type="entry name" value="G6PISOMERASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00765">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00174">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51463">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 7 8" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="4 7 8" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="5 7 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="356"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="387"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="550" mass="61081" checksum="5B94306EA524E5CC" modified="2010-01-19" version="1">MLKNINPTQTQAWKELTAHFEEVQDQQLTDLFAQDSERFAKFSATFGSEILLDYSKNLITQETLDKLFALAKETDLASAITAMFSGEKINQTEDRAVLHVALRNRSNTPIILDGEDVMPAVNAVLEKMKSFTNRIVSGEWKGYTGKEITDIVNIGIGGSDLGPYMVTEALKPYKTRLNMHFVSNVDGTHVAETLKGLNPETTLFLIASKTFTTQETMTNALTARDWFLATAQDSAHVAKHFAALSTNAPAVSEFGIDTDNMFEFWDWVGGRYSLWSAIGLSISLSIGFDNFVALLEGGHEMDKHFASTPLEQNLPVILALIGIWYNNFHGAETEAILPYDQYMHRFPAYFQQGNMESNGKYVDRGGNPVDYQTGPIIWGEPGTNGQHAFYQLIHQGTKLIPCDFIAPAISHNPIGDHHPKLMANFFAQTEALAFGKTKEQVEAEFVAAGKSLDEVKDLVPFKVFEGNRPTNSILVKEITPKTLGSLIALYEHKIFTQGVIWNILSFDQWGVELGKQLANKILPELNSADAVASHDSSTNGLINAFKQWRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-02-10" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0N9</accession>
    <name>D0Z0N9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CDP-diacylglycerol--serine O-phosphatidyltransferase</fullName>
            <ecNumber evidence="3">2.7.8.8</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_003103</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CDP-alcohol phosphatidyltransferase class-II family.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.8" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301868.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003103"/>
    <dbReference type="EnsemblBacteria" id="EEZ42070">
        <property type="protein sequence ID" value="EEZ42070"/>
        <property type="gene ID" value="VDA_003103"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1502">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1881748at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008444">
        <property type="term" value="F:CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003882">
        <property type="term" value="F:CDP-diacylglycerol-serine O-phosphatidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032049">
        <property type="term" value="P:cardiolipin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016270">
        <property type="entry name" value="PGS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025202">
        <property type="entry name" value="PLD-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12586">
        <property type="entry name" value="PTHR12586"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13091">
        <property type="entry name" value="PLDc_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00155">
        <property type="entry name" value="PLDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PLD phosphodiesterase" evidence="2">
        <location>
            <begin position="129"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="2">
        <location>
            <begin position="350"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ42070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="449" mass="51534" checksum="3EA873B1BB6B3CA5" modified="2010-01-19" version="1">MDSAIANTQRIEHLPCIAHKPENLETLFDASSFRERLLQEISQAKHRIYLVALYLQDDDAGRKILTALFEAKQQNPDLDIKVLVDWHRAQRGLIGAAKSDGNAALYREFSEKYTHNIEILGVPVRNREVFGVLHLKGFIIDDKVIYSGASLNDVYLAEHERYRYDRYHVIHNAKLADTMASFVLDNLVNSDAVNCLSQEHRPDTKSLKGAIRDFRINLQRAAYQFDGDRIQDDEVGLTPLVGLGKKKNRLNQQICTLIASAKTELTICTPYFNFPRSINKEVKRALRRGVKVTIVVGDKTANDFYIPPSEPFKTIAGLPYLYEVNLRHFAKQNEAAIARRQLAIHLWKHADNSFHLKGIWVDKTYMLVTGNNLNPRAWKLDLENAILIHDKNQLLLEQKEQELACILNHTQLIGSYKCIDKIDSYPLQVQKLIKRIRRVKADHILNQIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0P3</accession>
    <name>D0Z0P3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATPase of the PP-loop superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003107</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003107"/>
    <dbReference type="EnsemblBacteria" id="EEZ42074">
        <property type="protein sequence ID" value="EEZ42074"/>
        <property type="gene ID" value="VDA_003107"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2102">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01994">
        <property type="entry name" value="Alpha_ANH_like_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002761">
        <property type="entry name" value="Diphthami_syn_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01902">
        <property type="entry name" value="Diphthami_syn_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Diphthami_syn_2" evidence="1">
        <location>
            <begin position="6"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="224" mass="25490" checksum="A1CC91B438FB9580" modified="2010-01-19" version="1">MMKKIKVIISWSSGKDSTLVLCRLLEDPRYEVVGLYTTYVGEEVPFQATPLSVVEKQAHLLNLPLVLIALPEIFPPNEIYQQSVVDGLKQSQIDFDAVAFGDMFCNGIADYRRSYIEPVGWQCVFPLLGESSSKLATEIVSRGIKTRLITVDTSQLDSQYCGQWYNDELVKSLPDSADPCGEDGEFHTLVVDAPCFVEPLQLHWLNIERQPRFHYLRYQLVNNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0V5</accession>
    <name>D0Z0V5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cold shock protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_003169</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302062.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003169"/>
    <dbReference type="EnsemblBacteria" id="EEZ42136">
        <property type="protein sequence ID" value="EEZ42136"/>
        <property type="gene ID" value="VDA_003169"/>
    </dbReference>
    <dbReference type="GeneID" id="57340599"/>
    <dbReference type="eggNOG" id="COG1278">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2034748at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04458">
        <property type="entry name" value="CSP_CDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012156">
        <property type="entry name" value="Cold_shock_CspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011129">
        <property type="entry name" value="CSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019844">
        <property type="entry name" value="CSD_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002059">
        <property type="entry name" value="CSP_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00313">
        <property type="entry name" value="CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002599">
        <property type="entry name" value="Cold_shock_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00050">
        <property type="entry name" value="COLDSHOCK"/>
    </dbReference>
    <dbReference type="SMART" id="SM00357">
        <property type="entry name" value="CSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00352">
        <property type="entry name" value="CSD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51857">
        <property type="entry name" value="CSD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CSD" evidence="3">
        <location>
            <begin position="3"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ42136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="69" mass="7391" checksum="4D9002104FE51708" modified="2010-01-19" version="1">MSKATGIVKWFNEEKGFGFISQDNGGADVFVHFRAIASEGFKTLAEGQKVSFDVEQGQKGPQAANVVAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0V9</accession>
    <name>D0Z0V9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative acetate efflux pump MadN</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_003173</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302072.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003173"/>
    <dbReference type="EnsemblBacteria" id="EEZ42140">
        <property type="protein sequence ID" value="EEZ42140"/>
        <property type="gene ID" value="VDA_003173"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0697">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1515911at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004779">
        <property type="entry name" value="CO/AA/NH_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00950">
        <property type="entry name" value="2A78"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="87"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="112"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="135"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="173"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="204"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="235"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="260"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="3">
        <location>
            <begin position="139"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ42140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="297" mass="32921" checksum="BB5A589FE38ACE13" modified="2010-01-19" version="1">MGYLSAVTLLWAFSFSLIGVYLAGQVDAWFSVLTRVVLAALVFAPFLRSKHLHPSLALKLMAVGAFQLGLMYCFYYQSFLYLSVPEVLLFTIFTPIYVTLIYDALNRQFSPWYLLTAAIAVLGAAIIKFEGINQNFILGFCIVQGANLCFAIGQVGYKKIIEKEPQDLPQHTVFGWFYLGAIAVALPMYLLFGNSSKLPTSHLQWGILVYLGTVASGLGYFIWNKGATMVNAGALAIMNNALVPAGLIVNIVIWNRDVDYPRLIVGGIIIMASLWLNETWVKRKVAINQMIKGAEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0X8</accession>
    <name>D0Z0X8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hypothetical maturase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003192</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302120.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003192"/>
    <dbReference type="EnsemblBacteria" id="EEZ42159">
        <property type="protein sequence ID" value="EEZ42159"/>
        <property type="gene ID" value="VDA_003192"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3344">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1581397at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030931">
        <property type="entry name" value="Group_II_RT_mat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013597">
        <property type="entry name" value="Mat_intron_G2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08388">
        <property type="entry name" value="GIIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04416">
        <property type="entry name" value="group_II_RT_mat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="1">
        <location>
            <begin position="52"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="428" mass="49429" checksum="392153F0FEBF71AF" modified="2010-01-19" version="1">MRVYYSLYGHLLSKQRLYKGFKQVWKAKGAAGIDRQSLSDFASNLSDNLDQLLLELKTKQYKPQAVRKVEIPKDGGGVRLLGIPSVRDRVIQQTLNDLLTPIFEEQFHPSSFGYRPRRSCHDAINKATMFIRRYGMRHVVDMDLSKCFDKLDHELILTSIKKRITDSSILELIKQFLQSGVIANGEWHVTEIGSPQGGVISPLIANIYLDAFDQEMRKRNHRIVRYADDILIFCRSRRGAENALKQARKILENDLKLKVNQEKSHIAHSAEGVKFLGVEIGSNYTRIQPKKIKGFKRKLKQMTRRNSGKPLTMIIDALNPVLRGFGQYFKIANTSREFKSLAAWLRRRLRSIQLKLWKKPMKLHRRLKQLGYKPPFQLFIKMNSCKNAASPLASYAMPNQWFADLGLVNLGHIKTGYVFSNYAEWKYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0Z2</accession>
    <name>D0Z0Z2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Trk system potassium uptake protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">VDA_003206</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell inner membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the TrkH potassium transport family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302162.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003206"/>
    <dbReference type="EnsemblBacteria" id="EEZ42173">
        <property type="protein sequence ID" value="EEZ42173"/>
        <property type="gene ID" value="VDA_003206"/>
    </dbReference>
    <dbReference type="GeneID" id="57340384"/>
    <dbReference type="eggNOG" id="COG0168">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="756220at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015379">
        <property type="term" value="F:potassium:chloride symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003445">
        <property type="entry name" value="Cat_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004772">
        <property type="entry name" value="TrkH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02386">
        <property type="entry name" value="TrkH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006247">
        <property type="entry name" value="TrkH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00933">
        <property type="entry name" value="2a38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 10" id="KW-0630">Potassium</keyword>
    <keyword evidence="4 9" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="7"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="70"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="135"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="181"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="234"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="273"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="330"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="388"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="454"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="218"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="313"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="314"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="430"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="431"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR006247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR006247-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ42173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="481" mass="51858" checksum="DA742A4E9E4522EE" modified="2010-01-19" version="1">MVNFRPILFVLGLVLSKLALFMYVPTLVAFFTGTEGFIDFATAVIITHTVAFLCLTFGRTKEFKLSVRDMFLLTTLVWTVASAFAALPFVFINHISFTDAYFETMSGITTTGSTVLSGLDGMAPSILLWRSTLQWLGGVGFIVMAVAILPMLNVGGMRLFQTESSDWSDKSAPRTKSVAKNIVNVYLTLTALCIIGFILAGMNTFDAINHAFTTLSTGGYSTTDKSMNAFSHSAHWVATVFMFAGGLPFLLFVQALKKKKARLLFGDAQVKGYTVLVLVSSAIVAAWLVVKMNYQVLDAIRVSTFNIVSVVTTTGFGLDDFTAWGPLPSIIFGFIMLAGACSGSTSGGMKIFRFQIAFALLKKQMMQLIHPSGVFVQRYNQRPVTESVVSSVVAFALTYILTIVFVAAVLGLMGLDPITSITGAVTAVANVGPGMGTVIGPTGNFAGLPDAAKWVLSFGMLMGRLEILTVLVVFSPAFWRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1C9</accession>
    <name>D0Z1C9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Coenzyme A biosynthesis bifunctional protein CoaBC</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">DNA/pantothenate metabolism flavoprotein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Phosphopantothenoylcysteine synthetase/decarboxylase</fullName>
            <shortName evidence="6">PPCS-PPCDC</shortName>
        </alternativeName>
        <domain>
            <recommendedName>
                <fullName evidence="6">Phosphopantothenoylcysteine decarboxylase</fullName>
                <shortName evidence="6">PPC decarboxylase</shortName>
                <shortName evidence="6">PPC-DC</shortName>
                <ecNumber evidence="6">4.1.1.36</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="6">CoaC</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="6">Phosphopantothenate--cysteine ligase</fullName>
                <ecNumber evidence="6">6.3.2.5</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="6">CoaB</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="6">Phosphopantothenoylcysteine synthetase</fullName>
                <shortName evidence="6">PPC synthetase</shortName>
                <shortName evidence="6">PPC-S</shortName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="6" type="primary">coaBC</name>
        <name evidence="10" type="ORF">VDA_003343</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.</text>
    </comment>
    <comment type="function">
        <text evidence="7">Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>(R)-4'-phosphopantothenate + CTP + L-cysteine = CMP + diphosphate + H(+) + N-[(R)-4-phosphopantothenoyl]-L-cysteine</text>
            <dbReference type="Rhea" id="RHEA:19397"/>
            <dbReference type="ChEBI" id="CHEBI:10986"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:59458"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="EC" id="6.3.2.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>H(+) + N-[(R)-4-phosphopantothenoyl]-L-cysteine = (R)-4'-phosphopantetheine + CO2</text>
            <dbReference type="Rhea" id="RHEA:16793"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:59458"/>
            <dbReference type="ChEBI" id="CHEBI:61723"/>
            <dbReference type="EC" id="4.1.1.36"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
        <text evidence="6">Binds 1 FMN per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6 7">Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 2/5.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6 7">Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 3/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">In the C-terminal section; belongs to the PPC synthetase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.36" evidence="6"/>
    <dbReference type="EC" id="6.3.2.5" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302530.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003343"/>
    <dbReference type="EnsemblBacteria" id="EEZ42310">
        <property type="protein sequence ID" value="EEZ42310"/>
        <property type="gene ID" value="VDA_003343"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0452">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1346419at2"/>
    <dbReference type="UniPathway" id="UPA00241">
        <property type="reaction ID" value="UER00353"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004632">
        <property type="term" value="F:phosphopantothenate--cysteine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004633">
        <property type="term" value="F:phosphopantothenoylcysteine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015941">
        <property type="term" value="P:pantothenate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1950">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02225">
        <property type="entry name" value="CoaBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035929">
        <property type="entry name" value="CoaB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005252">
        <property type="entry name" value="CoaBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007085">
        <property type="entry name" value="DNA/pantothenate-metab_flavo_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036551">
        <property type="entry name" value="Flavin_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003382">
        <property type="entry name" value="Flavoprotein"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04127">
        <property type="entry name" value="DFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02441">
        <property type="entry name" value="Flavoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102645">
        <property type="entry name" value="SSF102645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52507">
        <property type="entry name" value="SSF52507"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00521">
        <property type="entry name" value="coaBC_dfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 7" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="6 7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 7" id="KW-0288">FMN</keyword>
    <keyword evidence="1 6 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 6 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavoprotein" evidence="8">
        <location>
            <begin position="7"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="DFP" evidence="9">
        <location>
            <begin position="186"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphopantothenoylcysteine decarboxylase" evidence="6">
        <location>
            <begin position="1"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphopantothenate--cysteine ligase" evidence="6">
        <location>
            <begin position="191"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="159"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="273"/>
            <end position="275"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="279"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="289"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="307"/>
            <end position="310"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="326"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="340"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="344"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ42310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="407" mass="43371" checksum="BD5E118AACF0B572" modified="2010-01-19" version="1">MQTLAGKKILLGISGGIAAYKCAELTRRLIERGAQVQVVMTKAAKEFITPLTMQAVSGNPVSDSLLNPAAEASMGHIELAKWADIVLLAPATADLIARVSAGMGNDLLTTLCLATDAPIAVAPAMNQQMYRNIATQENIATLARRGFEIWGPASGEQACGDVGPGRMLEPMQLVERIEHFFAPKALAGVKIAITAGPTCEAIDPVRYLTNHSSGKMGYAIAEAAAKQGADVTLISGPVNLATPAGVKRINVFSAKEMHQAALEQAVLHQIFIGCAAVADFRPAEVAEQKMKKQADSDEMVIRLVKNPDIIAAVAALEQQRPFTVGFAAETQNVEQYAMDKLSRKKLDLICANDVSAQNQGFNSDNNALTLFWQTGQKELPLCSKAELGQQLIAEIAALYQQSTTSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1G2</accession>
    <name>D0Z1G2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_003376</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ42343">
        <property type="protein sequence ID" value="EEZ42343"/>
        <property type="gene ID" value="VDA_003376"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ42343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="43" mass="4573" checksum="263E7451A9307043" modified="2010-01-19" version="1">MLGLVVVINATVLDEVEHWYEVGAGCEQLADLSDVVVLVAVFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1H0</accession>
    <name>D0Z1H0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">1,4-dihydroxy-2-naphthoate octaprenyltransferase</fullName>
            <shortName evidence="5">DHNA-octaprenyltransferase</shortName>
            <ecNumber evidence="5">2.5.1.74</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">menA</name>
        <name evidence="6" type="ORF">VDA_003384</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>1,4-dihydroxy-2-naphthoate + an all-trans-polyprenyl diphosphate + H(+) = a 2-demethylmenaquinol + CO2 + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:26478"/>
            <dbReference type="Rhea" id="RHEA-COMP:9563"/>
            <dbReference type="Rhea" id="RHEA-COMP:9564"/>
            <dbReference type="ChEBI" id="CHEBI:11173"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:55437"/>
            <dbReference type="ChEBI" id="CHEBI:58914"/>
            <dbReference type="EC" id="2.5.1.74"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Quinol/quinone metabolism; menaquinone biosynthesis; menaquinol from 1,4-dihydroxy-2-naphthoate: step 1/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the MenA family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.74" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302615.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003384"/>
    <dbReference type="EnsemblBacteria" id="EEZ42351">
        <property type="protein sequence ID" value="EEZ42351"/>
        <property type="gene ID" value="VDA_003384"/>
    </dbReference>
    <dbReference type="GeneID" id="57340166"/>
    <dbReference type="eggNOG" id="COG1575">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1472516at2"/>
    <dbReference type="UniPathway" id="UPA00079">
        <property type="reaction ID" value="UER00168"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046428">
        <property type="term" value="F:1,4-dihydroxy-2-naphthoate octaprenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009234">
        <property type="term" value="P:menaquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd13962">
        <property type="entry name" value="PT_UbiA_UBIAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01937">
        <property type="entry name" value="MenA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004657">
        <property type="entry name" value="MenA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026046">
        <property type="entry name" value="UBIAD1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13929">
        <property type="entry name" value="PTHR13929"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005355">
        <property type="entry name" value="UBIAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0474">Menaquinone biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="32"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="122"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="154"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="178"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="226"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="281"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ42351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="304" mass="32275" checksum="5852ED6D8D247089" modified="2010-01-19" version="1">MKASSSFAIWLDAARPKTLPLAVASIVCGSAVAAWHGSFSAAISLLALLTALLLQILSNLANDYGDAVKGTDNDNRLGPQRAIQSGLVTPNAMRKAMGLNIVLTAISGLSLIYIACDNAHEMFGFLLLGLMAIAASIAYTVGNKPYGYQGLGDLSVLMFFGWLGVAGTYYLQAGQIDSVVMLPATACGLLAVGVLNINNLRDIDNDRECGKLTLAVRMGPLWGRKYHLFLLAGSVLCMALFALFELHSPFGWLFILSTPLLFKHGKQVFQSTDGAALRPMMATMVKCALITNLLFAAGLILATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1H1</accession>
    <name>D0Z1H1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ATP-dependent protease ATPase subunit HslU</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Unfoldase HslU</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">hslU</name>
        <name evidence="8" type="ORF">VDA_003385</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the ClpX chaperone family. HslU subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302617.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003385"/>
    <dbReference type="EnsemblBacteria" id="EEZ42352">
        <property type="protein sequence ID" value="EEZ42352"/>
        <property type="gene ID" value="VDA_003385"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1220">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="718259at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009376">
        <property type="term" value="C:HslUV protease complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036402">
        <property type="term" value="F:proteasome-activating activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043335">
        <property type="term" value="P:protein unfolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00249">
        <property type="entry name" value="HslU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004491">
        <property type="entry name" value="HslU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48102:SF3">
        <property type="entry name" value="PTHR48102:SF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00390">
        <property type="entry name" value="hslU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="6">
        <location>
            <begin position="49"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="domain" description="ClpB_D2-small" evidence="7">
        <location>
            <begin position="335"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="18"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="60"/>
            <end position="65"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="256"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="321"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="393"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ42352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="443" mass="49923" checksum="786A468366ED1DD7" modified="2010-01-19" version="1">MSEMTPREIVHELDRHIIGQDKAKRAVAIALRNRWRRMQLPEALRVEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGYVGKEVETIIRDLTDVAVKMTHQQAMEKVRYRAEELAEDRILDVLLPPVRDAWGQNENSDTNSATRQSFRKKLREGQLDDKEIELDIAAPQMGVEIMAPPGMEEMTNQLQGMFQNLAGNTTKKRKLKIKDALKAVTEEEAAKLVNQEELKEQAIHAVENNGIVFIDEIDKICKRGESSGPDVSREGVQRDLLPLVEGSTVSTKHGMVKTDHILFVASGAFQVAKPSDLIPELQGRLPIRVELEALSSHDFKRILTEPNASLTEQYRALMATESVNIEFTEEGIDALADAAWQVNERTENIGARRLHTVMERLMEDLSYDATEKSGESFKITAEYVKERLGEFVEDEDLSRFIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1I8</accession>
    <name>D0Z1I8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_003402</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302650.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003402"/>
    <dbReference type="EnsemblBacteria" id="EEZ42369">
        <property type="protein sequence ID" value="EEZ42369"/>
        <property type="gene ID" value="VDA_003402"/>
    </dbReference>
    <dbReference type="GeneID" id="57340148"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="990666at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ42369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="299" mass="33266" checksum="EFE215E66DAE23C0" modified="2010-01-19" version="1">MNIRDLEYLVALAEHKHFRKAAEACYVSQPTLSGQIRKLEDELGVSLLERTSRRVLFTDAGLSLVAQAQKVLLEVKILTELASMQGESMTGPLHIGFIPTVGPYLLPHIIPTLKEAFPDLELFLHEAQTHQLVQQLEDGKLDCIILAAVKETEPFIELPLYDEPMVIAVPETHPWANKDEVDMAQLHGESLLMLEDGHCLRNHAMGFCLAAGAHDDGRFKATSLETLRNMVAAGSGITLLPQLATPKEHCRDGVCYIKAKQPVPTRLITLAYRPGSPLKARYEKLADVIRERMPEVLVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1J7</accession>
    <name>D0Z1J7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Site-specific DNA-methyltransferase (adenine-specific)</fullName>
            <ecNumber evidence="3 8">2.1.1.72</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_003411</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:15197"/>
            <dbReference type="Rhea" id="RHEA-COMP:12418"/>
            <dbReference type="Rhea" id="RHEA-COMP:12419"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90615"/>
            <dbReference type="ChEBI" id="CHEBI:90616"/>
            <dbReference type="EC" id="2.1.1.72"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the N(4)/N(6)-methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.72" evidence="3 8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302664.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003411"/>
    <dbReference type="EnsemblBacteria" id="EEZ42378">
        <property type="protein sequence ID" value="EEZ42378"/>
        <property type="gene ID" value="VDA_003411"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0338">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1206955at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1020.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023095">
        <property type="entry name" value="Ade_MeTrfase_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012263">
        <property type="entry name" value="M_m6A_EcoRV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012327">
        <property type="entry name" value="MeTrfase_D12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30481">
        <property type="entry name" value="PTHR30481"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02086">
        <property type="entry name" value="MethyltransfD12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000398">
        <property type="entry name" value="M_m6A_EcoRV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00505">
        <property type="entry name" value="D12N6MTFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00571">
        <property type="entry name" value="dam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 8 9" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="7">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000398-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ42378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="280" mass="32212" checksum="D4D7D4A54FC9B338" modified="2010-01-19" version="1">MKKHRAFLKWAGGKYSLVEDIERHLPPARKLVEPFVGAGSVFLNTDFEHYLLADINPDLINLYNILKDRPEQFIADAKRLFTPEFNCKEEYLRIRSEFNKSHDPYQRSLYFLYMNRHGFNGLCRYNKKGGFNVPFGSYKKPYFPEQEMYYFAEKAKRATFVCEGYQQTFSRARKGSVIYCDPPYAPLSTTANFTSYAGNGFSLDDQAALADVAERAARERDIAVLISNHDTTLTRRLYIGAELSVVKVKRTISRNGNGRNKVDELLALFRPTNSDTTISD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1Q3</accession>
    <name>D0Z1Q3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_003467</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303531.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003467"/>
    <dbReference type="EnsemblBacteria" id="EEZ42434">
        <property type="protein sequence ID" value="EEZ42434"/>
        <property type="gene ID" value="VDA_003467"/>
    </dbReference>
    <dbReference type="GeneID" id="57340076"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1369205at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13581">
        <property type="entry name" value="HATPase_c_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07228">
        <property type="entry name" value="SpoIIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="141"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ42434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="490" mass="56658" checksum="12B61B0DAE507A40" modified="2010-01-19" version="1">MNYPLYQQQFKLTINELKQIRNWINDKHQRLSFCPTITQKLQLIISEYGTNLLNHQAVPASHIQLIGHQTANEYQFTILDNGSHWLAFEEQLNQAQFPKQPSTNHMGLALLKSMFDNYQYTLSEQGNNFSFSIDKDQEKPRLLLIDDSSSQLTYLASLLQEDYQITMFSSSTEGLDWLKDHSCELVITDIHMPEMDGFHFRQHVAKQPRHSLLPFIFLTGDLNRSTQSAASQLEIDDYLKKPIDKETLFSVIERVLKRHRRLQSHLEHALSQHISPQVRQENDHRRSHNLQIEYHQDPPDSGDFLLTHYCQDERELIVVGDHMGSGLIARTNGSGWISFIRGLFCAGIESPQQLLTLLNQEIYQTSHSQLICLMIIEIQQNSQITIYNSAMPAPLLVGLEHSEYQQEHISLLGLNEQITIECKHYDLLSEQSLHIASDGIFEQKLSQQQQKQIQSKDKTIRGAYLWESSLHIEDDKTLVTIYLAEPISEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1R3</accession>
    <name>D0Z1R3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glycos_transf_1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003477</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303557.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003477"/>
    <dbReference type="EnsemblBacteria" id="EEZ42444">
        <property type="protein sequence ID" value="EEZ42444"/>
        <property type="gene ID" value="VDA_003477"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="694191at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="200"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="378" mass="42297" checksum="FCD9DBFA1612D1A0" modified="2010-01-19" version="1">MKKKIAYVLPSFPTLSETFVGVEMRAMERQGHSIQPFAFSKAQKGQQADRVLQRKCIYLDSSPYISLMPLCFSYRAHRFLIRQQGFSYLGLLRQGGQLAQRVKMTQCQHIHAHFAWHSAAIAITAAKLLNISVSFVGHGADIYASPQDLEHKLQHVDFACAVTAQMADELKAQTHKPIHHIACGIEYELYPALLDTFAPTKQLLFIGRLVEKKGLHILIEALDGTGITLDIVGDGPLLPDLQNEIHQRQLTSQVRFLGSQDASWFRHHAKDYSALAAPFLIAQNGDQDTGPLVIKEAMALGLPVITSDLSGCNEILTDLTGVQVKMGEPRLFRQAILNHFKRSRNELEQQRLSAYQHVMTHFNAGTQAHKLSQFIEAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-06-02" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1R9</accession>
    <name>D0Z1R9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_003483</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303572.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003483"/>
    <dbReference type="EnsemblBacteria" id="EEZ42450">
        <property type="protein sequence ID" value="EEZ42450"/>
        <property type="gene ID" value="VDA_003483"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3307">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1897460at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007016">
        <property type="entry name" value="O-antigen_ligase-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031726">
        <property type="entry name" value="PglL_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021797">
        <property type="entry name" value="Wzy_C_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15864">
        <property type="entry name" value="PglL_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04932">
        <property type="entry name" value="Wzy_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11846">
        <property type="entry name" value="Wzy_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="51"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="178"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="211"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="234"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="258"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="351"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="386"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="409"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="442"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="domain" description="PglL_A" evidence="5">
        <location>
            <begin position="174"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="domain" description="Wzy_C_2" evidence="4">
        <location>
            <begin position="387"/>
            <end position="574"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF11846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF15864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ42450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="583" mass="66630" checksum="9E0564AFD8415255" modified="2010-01-19" version="1">MAVVQLQGTRLEPQQISKPLVRYFLVSIAALFLLAMHYFQHNPGGSGLELSFNVTSWIPFSIAIALGLAEICRQKIWRYSKLTLILLLCCVLLSLPVFYPNADASQVSFRLFTLWSGWLFFVALQQFTFTHKQRQRILWFILAGILIETLFAWVQFLYLKPGNPFGYDTLANRPYGIFQQPNVMASFLATGLVLSAYLLARVPMYRGKWNWQHLILQLTPVLIIPILVVLSSRTGWLGAIVGVGLMIPYLHRFAPKKLWIGWLLMVAAGLMSAWGLTAERSWAPADGRVSLQSLRSVHIPQAFDMFKAEPMTGYGYGRFETAYITQTAIWHHDDPKLPAGVPSLDHPHNELVFWAAEGGIIPLLGLLIAATAVFLKIKKARQGTQLALIGLFFPITLHTQLEYPFYHSLIHWIVFIIFIYWIDNLTAKYYRYQATYVLTLKVFSIALPIVITSFMITTLYSGAQLTKFETSKPINVDYLMKVNNPWAWQNRFEWDLHVTQLQIGVATEKPQLIEDYINWATIKAQTWPRPALYQNLILAYNQLNNHKQAEQIEQEAQFLFPNMSFSHSQAVTTQAKPQLSQAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1U1</accession>
    <name>D0Z1U1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">Cell shape-determining protein MreC</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4 5">Cell shape protein MreC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_003505</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in formation and maintenance of cell shape.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the MreC family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303632.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003505"/>
    <dbReference type="EnsemblBacteria" id="EEZ42472">
        <property type="protein sequence ID" value="EEZ42472"/>
        <property type="gene ID" value="VDA_003505"/>
    </dbReference>
    <dbReference type="GeneID" id="57340023"/>
    <dbReference type="eggNOG" id="COG1792">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="837894at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042177">
        <property type="entry name" value="Cell/Rod_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042175">
        <property type="entry name" value="Cell/Rod_MreC_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007221">
        <property type="entry name" value="MreC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34138">
        <property type="entry name" value="PTHR34138"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04085">
        <property type="entry name" value="MreC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038471">
        <property type="entry name" value="MreC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00219">
        <property type="entry name" value="mreC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0133">Cell shape</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="297"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="306"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00032089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR038471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ42472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="320" mass="35431" checksum="79DD512CB4BDA191" modified="2010-01-19" version="1">MKPIFGRGPSLQLRLFLAILLSAGLMLADSRLDAFANVRYFLNSAIAPLQYAANLPRELLDSMSGQFSSRQTLLVENKALKRDLLVMQSNVLLLDQLKQENKRLRDLLGSPFVRDERKMITEVMAVDSDPYSHQVMIDKGRIDGVYEGQPVINENGVVGQVSYVGAHNSRVLLLIDPMHAIPVQVVRNDIRAIASGTGQSNEIQLEHVPSSTDIQVGDKLVTSGLGGRFPEGYPVGYVTEFSFDNKRPFAQVKARPSVNFDRLRYLLLVWPTPQHKETDQDVAASTVIPTVAAQVASPKVEPIPTEPNKPKAKKEVTNVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1U6</accession>
    <name>D0Z1U6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">TldD protein probably a protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_003510</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase U62 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303649.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003510"/>
    <dbReference type="EnsemblBacteria" id="EEZ42477">
        <property type="protein sequence ID" value="EEZ42477"/>
        <property type="gene ID" value="VDA_003510"/>
    </dbReference>
    <dbReference type="GeneID" id="57340017"/>
    <dbReference type="eggNOG" id="COG0312">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="806701at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045569">
        <property type="entry name" value="Metalloprtase-TldD/E_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045570">
        <property type="entry name" value="Metalloprtase-TldD/E_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002510">
        <property type="entry name" value="Metalloprtase-TldD/E_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025502">
        <property type="entry name" value="TldD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035068">
        <property type="entry name" value="TldD/PmbA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036059">
        <property type="entry name" value="TldD/PmbA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01523">
        <property type="entry name" value="PmbA_TldD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19289">
        <property type="entry name" value="PmbA_TldD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19290">
        <property type="entry name" value="PmbA_TldD_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004919">
        <property type="entry name" value="TldD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111283">
        <property type="entry name" value="SSF111283"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PmbA_TldD" evidence="3">
        <location>
            <begin position="36"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="PmbA_TldD_M" evidence="5">
        <location>
            <begin position="125"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="PmbA_TldD_C" evidence="4">
        <location>
            <begin position="247"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF19289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF19290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ42477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="482" mass="51123" checksum="61403803A6AD7B6A" modified="2010-01-19" version="1">MTLNTVEKTMLAQADMGQDELQAILAKIATRDVDYADIYFQSCWHESLVLEDSIIKDGSFNIDRGVGVRAISGEKTGFAYSDQINLLALEQSAKAARGIARQGRSAQVQAFVPVTASGIYAPVDPLTTMDKQQKIELLQQIDSYIRTKEPLVTEVSVSINGVNEQILVAGLDGTYAADVRPLVRLSISVLVERGDKRERGSAGGGGRYGYQAFLAEDENGKSVALHFADEAIRQALVSLEAQAAPAGTMPVVLGAGWPGVLLHEAVGHGLEGDFNRKGSSMFSGQLGEQVTSSLCTIVDDGTLPDLRGSINVDDEGTPGQYNVLVEGGKLKGYMQDKHNARLMGVAPTGNGRRESYAHLPMPRMTNTYMLPGEHSPEEIIASVKKGIYAPNFGGGQVDITSGKFVFSASEAYLIENGKITTPIKGATLVGSGIEAMQQVSMVGNDLQIDKGVGVCGKAGQSIPVGVGQPTLKLDSMTVGGTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1U9</accession>
    <name>D0Z1U9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Magnesium transporter MgtE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_003513</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Acts as a magnesium transporter.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the SLC41A transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003513"/>
    <dbReference type="EnsemblBacteria" id="EEZ42480">
        <property type="protein sequence ID" value="EEZ42480"/>
        <property type="gene ID" value="VDA_003513"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2239">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.60.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006668">
        <property type="entry name" value="Mg_transptr_MgtE_intracell_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038076">
        <property type="entry name" value="MgtE_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006669">
        <property type="entry name" value="MgtE_transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006667">
        <property type="entry name" value="SLC41_membr_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036739">
        <property type="entry name" value="SLC41_membr_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43773">
        <property type="entry name" value="PTHR43773"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01769">
        <property type="entry name" value="MgtE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03448">
        <property type="entry name" value="MgtE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00924">
        <property type="entry name" value="MgtE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161093">
        <property type="entry name" value="SSF161093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00400">
        <property type="entry name" value="mgtE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0129">CBS domain</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="280"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="328"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="355"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="393"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="8">
        <location>
            <begin position="108"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="8">
        <location>
            <begin position="172"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ42480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="417" mass="45115" checksum="E0C365C388BD1E1E" modified="2010-01-19" version="1">MEPEDIAHLLEASPPKERQVLWQLTDPEEQGDILEELSEDVKDGIVSQMDPEKLAAVTEGMESDDIAYVLRSLPDDKYQEVLAQMDATDRHRIEKALAYPEDSAGGIMSTDFITIRGDVSTDVVLRYLRMRGELPEATDTLYVVDEEEKLIGHISLSTLVTTQPDVEIKDVMDDTDEAIPVDMDDGEIANLFERRNWLSAPVVDANNQLVGRITIDDVVDVIREDAEHSMMSMAGMDDDEDTFAPVLKSAKSRSIWLGVNVLTALAAASVSNMFEDTLSKMAAIAVLMTIVPSMGGVAGNQTVALVIRGLAVGHIGDSNTRWLLSKEARVGLINGLLWALIIGGVVVLWKGNLILGAIIAGAMLTNLFVAGVAGVVIPIMLKKLKIDPALAGGMALTTCTDIVGLFVFLGLATVFLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1Z9</accession>
    <name>D0Z1Z9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative efflux (PET) family transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001985</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001985"/>
    <dbReference type="EnsemblBacteria" id="EEZ40953">
        <property type="protein sequence ID" value="EEZ40953"/>
        <property type="gene ID" value="VDA_001985"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1289">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032692">
        <property type="entry name" value="YccS_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12805">
        <property type="entry name" value="FUSC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="436"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="471"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="501"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="domain" description="FUSC-like" evidence="2">
        <location>
            <begin position="72"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="695" mass="78688" checksum="41355AD346CBF421" modified="2010-01-19" version="1">MTISNLLLRFPSLRSLLNLRTNIAALSFVTCSVPFFLMGHVTMGIALSLGSISCGLADTSSVTKYRLLDYLVTIPLFFVVSLGVEAVFPHSILFSASLAVVSFALFMLAVLSPRLGAIGFATILLAIYAMLVHQEGRSIWLVPTWLTAGAIWYVLWQLIAMYFLPNQESKDILSDLYQALAKKLMIHDRGFLFSTDKNQLFIESARSRSQITTLSKTLEYRIHQQLSAGEDSASLQDITRFLKIAERISEQTRLMYFSPTPELKQHCPQWLDRIHQANQTIIGYLSQVTVNNVHQLPFPRIDFDALRSFPIPDNAKEESVAAHAFINKLDIVYLSLQQLSCEITEVSSSTVSKPIVLSWKWQEVAIKLASQMTMKSSYFRHALRGSLSLTTGLILVRLFELDFGFWTLMTSLLVLRPNLSMTWTRLLQRITGTLSGLIVVAALLHFQVSSDILPFIFCIAAVLFFHTTTKQYGWAVFFVTLFVFSGFSLNGQGNMIMLPRLDNTILGVTLPLLFVFIIAPGWQKKSFPLQLATTVQDYIVYLTALNQYIGNKNGELSLHVQHQYQRCVLNDTNLFDHWMGYLGEPHLSAQLGEYILLCSRSSNVILRIITQLNENRDELNHDDETTSALNQAIVALQDLQMRLGESKQQADIYSYISKRKDAIYQSFSHIENEVYRLDNKTLLKLLSKEVQLLSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2B5</accession>
    <name>D0Z2B5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4435 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000566</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304730.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39546">
        <property type="protein sequence ID" value="EEZ39546"/>
        <property type="gene ID" value="VDA_000566"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1844659at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029492">
        <property type="entry name" value="DUF4435"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14491">
        <property type="entry name" value="DUF4435"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4435" evidence="1">
        <location>
            <begin position="34"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="319" mass="36919" checksum="3BB956EA757835EC" modified="2010-01-19" version="1">MSFLDYLNNELSNENIEHHLFLIDFNPSKKVVHAFFEGKTDESFYGTAIRNMLDDDYELKTYICGKKDSVLYHYREIGHKTSIIQPLLFFIDKDIDNIIPVDVVRAETIYETTLYAIENYIVNSTSLEQVWAEIFRQTSGTSVSLKLKELFEIAHNEYNTIALELMSWVLYQRRKGGVRLNLDCIKTTDLFSIDENLKLTKLFTKEELYNYLSVKTKVTTSPEDFLGIESCKHELSKFEIKEISRGHNEMDFFIEFVKVLKEVSSSVSAVNIKAHVEINSANVIDIMGPRIRPHDSLASFLTKHIGSIEEPMMVERRTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2B7</accession>
    <name>D0Z2B7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Multidrug export protein MepA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Multidrug resistance protein NorM</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Na(+)/drug antiporter</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_000568</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304733.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000568"/>
    <dbReference type="EnsemblBacteria" id="EEZ39548">
        <property type="protein sequence ID" value="EEZ39548"/>
        <property type="gene ID" value="VDA_000568"/>
    </dbReference>
    <dbReference type="GeneID" id="57342952"/>
    <dbReference type="eggNOG" id="COG0534">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="216729at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13143">
        <property type="entry name" value="MATE_MepA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045070">
        <property type="entry name" value="MATE_MepA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006603">
        <property type="entry name" value="DinF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="61"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="97"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="171"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="196"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="237"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="277"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="322"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="367"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="394"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="419"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00030855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="452" mass="49389" checksum="88D7D49BC2638514" modified="2010-01-19" version="1">MTSHANSATLALRDDSIYALFWRYSLPTIAAMLVTGVYVAIDGMFIGHFIGEDGLAAIILGYPIGSILYALGALIGMGASALVSMKLGEGKQKQAQLIVGNAFSLSLIISLITCILGINYGKYALIWLGAEGHILQMATDYLFWYFAMGAFAVLSMAFSALLRNDGQPNRVTYIMILGGVLNIILDWLFIVVIPWALTGAAIATMLSQAVTAILCLQHFFSDRTQLKITWNTLKLRVAIVVRIIKLGTSSLLMYMYLSVVLMLHNKAFLTVGSALHVAAYGVVTYAESFFYLVFEGIALGIQPITSFNYGAGQQQRVLQARNLAIAITIAFSLLGVVVLYSFPETAVFVFAGDNPTLLPEAVQGMQLYFWGLPFEGLLLVGATYFQSINRVKQASILTGGKLIFITLFVILFAKLWGVTGVWLALPVCSLLLVIWMAGQMIKEQKSYQNENK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2D9</accession>
    <name>D0Z2D9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000590</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304802.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000590"/>
    <dbReference type="EnsemblBacteria" id="EEZ39570">
        <property type="protein sequence ID" value="EEZ39570"/>
        <property type="gene ID" value="VDA_000590"/>
    </dbReference>
    <dbReference type="GeneID" id="57342933"/>
    <dbReference type="eggNOG" id="ENOG502Z85M">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="709276at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043776">
        <property type="entry name" value="DUF5718"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18985">
        <property type="entry name" value="DUF5718"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="276" mass="30582" checksum="EF5FBC86751C63DF" modified="2010-01-19" version="1">MKFEKMIGFGVAGNFAGHLEQAGEAKDFLQVKVQEEIQPKAIFPFYVPADDAGFLATYPLSSSTVVTPNDADNLQIEPEVALICDIEYIDNTVVGLYPRFFAAYNDCSIRKPNAKKISEKKNWGANTKGLSETLLAVDSLKMGGVLDSYRIASFHKRDGEIHRYGEDSPVSGYSYFHQKLLNWIMDRMNNQQDVGPTENIAQLLEKAQYPTQAVISIGATRYTEYGETTFLQPGDTSIVVVYDAKLYTESEIEQMATSNDFAQDGLSALVQKVVAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2L9</accession>
    <name>D0Z2L9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">2-oxoglutarate/malate translocator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_000670</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305009.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39650">
        <property type="protein sequence ID" value="EEZ39650"/>
        <property type="gene ID" value="VDA_000670"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0471">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="626718at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030676">
        <property type="entry name" value="CitT-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001898">
        <property type="entry name" value="SLC13A/DASS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42826">
        <property type="entry name" value="PTHR42826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00939">
        <property type="entry name" value="Na_sulph_symp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002457">
        <property type="entry name" value="DASS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00785">
        <property type="entry name" value="dass"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="36"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="187"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="217"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="261"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="290"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="323"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="361"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="388"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="445"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="473" mass="50572" checksum="A277E5E1F75CAB76" modified="2010-01-19" version="1">MKLAFKWPQLLAVIAVTALLYSQLPPAGLSTEGYHLALLFIATIASIVLNIMPTGAIAVLSIAVYCIILPVEPTGKAAITAELHDFNNSLIWLIVIAFMMARAFAKTGLGERISLVLLSKFGQSSLRIAYCLGLADYILAPATPSNTARFAITSPIANSLAKTINEKDRKLGEFLISNASAMNDASAVGFSTAFAGNLALIGIASTLLGINLTFGTWVTYLLVPSLCLFLVIPFVLYLFISPDTKQTPEAPVFAKEKLKQLGRISIPELMLAIIFVALVVMWIFGAALNLNATGAAFIGLSAMLMLGVLSWDDIKAEKGAWDTLIWFSVLMGMANHLRSLGVVKWLGTNVSDFLSSAMHGASPTIFLLVLMLFFLLTSYLFASGTAKVVALGGVIIGSLLTLGVQPMIALLSVAGVMNIGCNLTTYSHARNPLAMGYGYHTPGKWMVNGLVICGTGFVLFMLTGLIWWHLLGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2R3</accession>
    <name>D0Z2R3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000714</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000714"/>
    <dbReference type="EnsemblBacteria" id="EEZ39694">
        <property type="protein sequence ID" value="EEZ39694"/>
        <property type="gene ID" value="VDA_000714"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1933111at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="223" mass="26030" checksum="9DFFA9F01A431D3E" modified="2010-01-19" version="1">MSFIISMVIYMQQNLVQKADYRLAVEFEAQSGIPAYGVNEQNRKEILESALKHTQIQSEDDFEKVVLWLASGEYLEEQQLAFDFIARFSDVYQQKMLSMYPKLLLDSTSEFVERSVVGLLSETELVAIKHVPSDFYSDQAYQYFCFLIKWLNCLSKQESKITNEVMQLIDRVEEKDHLANQLVFETKAYNRTIMRLQDKINLMLSTVAKARLNEIELFSNETT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2S4</accession>
    <name>D0Z2S4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000725</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305171.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000725"/>
    <dbReference type="EnsemblBacteria" id="EEZ39705">
        <property type="protein sequence ID" value="EEZ39705"/>
        <property type="gene ID" value="VDA_000725"/>
    </dbReference>
    <dbReference type="GeneID" id="57342766"/>
    <dbReference type="eggNOG" id="ENOG50339IW">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021677">
        <property type="entry name" value="DUF2986"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11661">
        <property type="entry name" value="DUF2986"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="59" mass="6770" checksum="AE28189C0F9B8256" modified="2010-01-19" version="1">MNRKKKVKQTLLKKAKKSNAKMHKSNKPKYISKADREKMALEEEQAAVETPIEPSDVSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2V3</accession>
    <name>D0Z2V3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Phosphosugar mutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">VDA_000754</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305255.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000754"/>
    <dbReference type="EnsemblBacteria" id="EEZ39734">
        <property type="protein sequence ID" value="EEZ39734"/>
        <property type="gene ID" value="VDA_000754"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1109">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="637615at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016868">
        <property type="term" value="F:intramolecular transferase activity, phosphotransferases"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005845">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005846">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005843">
        <property type="entry name" value="A-D-PHexomutase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016066">
        <property type="entry name" value="A-D-PHexomutase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005841">
        <property type="entry name" value="Alpha-D-phosphohexomutase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02879">
        <property type="entry name" value="PGM_PMM_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02880">
        <property type="entry name" value="PGM_PMM_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00408">
        <property type="entry name" value="PGM_PMM_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00509">
        <property type="entry name" value="PGMPMM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="SSF53738"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="SSF55957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00710">
        <property type="entry name" value="PGM_PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PGM_PMM_I" evidence="9">
        <location>
            <begin position="41"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_II" evidence="10">
        <location>
            <begin position="214"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_III" evidence="11">
        <location>
            <begin position="322"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_IV" evidence="8">
        <location>
            <begin position="488"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ39734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="568" mass="62130" checksum="4D644AFABAC7EE72" modified="2010-01-19" version="1">MKTEISRWLDRDPDPKTRLELEELVAAHNIAELDERFRGRLEFGTAGLRGVVGAGPNRMNRLVIQETATGLGHYLIQTIDNAKEKGVVIGYDGRPDSKQFAHDAAGMLTALGIKVYLTYKVAPTPVVAFGVHHLGTAAAIVVTASHNPPEYNGFKVYWENGAQIIPPHDSGIASEIDKAAAMHLPHADLIQAEQQGLLIWLDDEYYQDYRAAQNHNPLLQNHTKPEGIAIAYTAMHGVGAEMAETLLKDAGFEQVHSVAAQREPDGAFPTVKFPNPEEAGAMDMVIAEAQKYNAVLACANDPDADRFAVAVRTEDGNYKMLTGDQVGILFGHYLLNHAPSDERLVGNTIVSSSLLAKIAKAADATFYQTLTGFKWLTNVAMQKQTDQNKFLFAYEKALGYTIGRTVWDKDGLSALVVFAQLTAELAAQGLTVWDRLESIYREHGLYINAQRSLALDPTSPPVGDTLRQNPPSEIAGLAVEVIDDLKVSLKTFVDGTVEAIDLPSSDVLIYHLAGGARVVVRPSGTEPKLKCYYEVIEPMTHEDSLCHSQQRAQQAMDDLIDKHQASLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2W3</accession>
    <name>D0Z2W3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Major outer membrane lipoprotein Lpp</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">lpp</name>
        <name evidence="8" type="ORF">VDA_000764</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">A highly abundant outer membrane lipoprotein that controls the distance between the inner and outer membranes. The only protein known to be covalently linked to the peptidoglycan network (PGN). Also non-covalently binds the PGN. The link between the cell outer membrane and PGN contributes to maintenance of the structural and functional integrity of the cell envelope, and maintains the correct distance between the PGN and the outer membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotrimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell outer membrane</location>
            <topology evidence="3">Lipid-anchor</topology>
            <orientation evidence="3">Periplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Secreted</location>
            <location evidence="3">Cell wall</location>
            <topology evidence="3">Peptidoglycan-anchor</topology>
        </subcellularLocation>
        <text evidence="3">Attached via its lipidated N-terminus to the inner leaflet of the outer membrane. Attached to the peptidoglycan network (PGN) via its C-terminus.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Lpp family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305280.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000764"/>
    <dbReference type="EnsemblBacteria" id="EEZ39744">
        <property type="protein sequence ID" value="EEZ39744"/>
        <property type="gene ID" value="VDA_000764"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4238">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1991143at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042834">
        <property type="term" value="F:peptidoglycan binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030258">
        <property type="term" value="P:lipid modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043580">
        <property type="term" value="P:periplasmic space organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00843">
        <property type="entry name" value="Lpp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006817">
        <property type="entry name" value="Lipoprotein_leucine-zipper_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016367">
        <property type="entry name" value="MOM_Lpp"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38763">
        <property type="entry name" value="PTHR38763"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04728">
        <property type="entry name" value="LPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002855">
        <property type="entry name" value="Murein-lipoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3" id="KW-0134">Cell wall</keyword>
    <keyword evidence="2 3 5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 3 5" id="KW-0564">Palmitate</keyword>
    <keyword evidence="3 4" id="KW-0572">Peptidoglycan-anchor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018859" description="Major outer membrane lipoprotein Lpp" evidence="6">
        <location>
            <begin position="27"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="repeat" evidence="3">
        <location>
            <begin position="30"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="LPP" evidence="7">
        <location>
            <begin position="32"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-murein peptidoglycan lysine" evidence="3 4">
        <location>
            <position position="84"/>
        </location>
    </feature>
    <feature type="lipid moiety-binding region" description="N-palmitoyl cysteine" evidence="3 5">
        <location>
            <position position="20"/>
        </location>
    </feature>
    <feature type="lipid moiety-binding region" description="S-diacylglycerol cysteine" evidence="3 5">
        <location>
            <position position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR002855-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR002855-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ39744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="84" mass="8948" checksum="5136D7B506DBB413" modified="2010-01-19" version="1">MNRKVTILAGVILSATLMGCSSSSEMQQLTNKVDALSDQVSALQGQQDQLAGAVNDARAASDAAYQEAMRANQRIDNIRGSYTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2X9</accession>
    <name>D0Z2X9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ribonuclease T2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000780</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the RNase T2 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305331.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000780"/>
    <dbReference type="EnsemblBacteria" id="EEZ39760">
        <property type="protein sequence ID" value="EEZ39760"/>
        <property type="gene ID" value="VDA_000780"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3719">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1693572at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033897">
        <property type="term" value="F:ribonuclease T2 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.730.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001568">
        <property type="entry name" value="RNase_T2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036430">
        <property type="entry name" value="RNase_T2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033130">
        <property type="entry name" value="RNase_T2_His_AS_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11240">
        <property type="entry name" value="PTHR11240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00445">
        <property type="entry name" value="Ribonuclease_T2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55895">
        <property type="entry name" value="SSF55895"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00531">
        <property type="entry name" value="RNASE_T2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018799" evidence="3">
        <location>
            <begin position="19"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="237" mass="27638" checksum="63688747F7B50C2C" modified="2010-01-19" version="1">MKKTIIVLCLTFANITYAEDSFEVSVKNAPSGLYNTNVVAMTWMPTFCNIRQLKNDENCVNDFKLHGIWPYYHATIDNDNILNYHPSNCYHSEGCTSTKDCDISKETISFLDNDISMQRSYPKNVTLWSHEWKKHGTCSGLNQKDYFELANVYLPKISNHYEKIKILAQRNKNNSVDVNEIYNLLPHNTSLRCYNIQGDNYLFEVNFFFDRLGKEYNKVKTQIGDRCDGMVFLSWLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z379</accession>
    <name>D0Z379_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Membrane fusion protein (MFP) family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">VDA_000880</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell inner membrane</location>
            <topology evidence="9">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000880"/>
    <dbReference type="EnsemblBacteria" id="EEZ39860">
        <property type="protein sequence ID" value="EEZ39860"/>
        <property type="gene ID" value="VDA_000880"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0845">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006144">
        <property type="entry name" value="Secretion_HlyD_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010129">
        <property type="entry name" value="T1SS_HlyD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01843">
        <property type="entry name" value="type_I_hlyD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00543">
        <property type="entry name" value="HLYD_FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="174"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ39860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="464" mass="51589" checksum="5C05683AC60A3CFA" modified="2010-01-19" version="1">MANNDKKNTLSNLDFVDDKSAALLLNTPTSARILLWVILLFFIVAFAWASVAKLDKVTTGIGKVIPSSQLQVVQNLEGGIVKQVMVREGEHVTKGQKLLLIDDTLFQSDYKEKDQSVAGLQADIIRFNGLLASIKVDKSQASKDWQKTVVIKPAQLAFTSEYKKSHPDKVRRQQNEYRDNISNLENQLSVVAQQISQKQRELTENQSRIANLQRSYNIALKEYNITKPLADEGVVPKIELLKLQRSLNDTKRDLTSARLQAPVAKSAIKEATFKYMDIALQFRSDIQSKLNDTSDQLSSMNETRIGLEDRVKRTTVVSPVTGTIQKIYVNTVGGVIQPGMNLIEIVPTEDTLLIEAKIAPQDIGFLRPGLKAIVKFTAYDFTSYGGLDGVVETISADTIQDKEGNSFYQVRVRTDKNSLTAPDGESLPIIPGMTASVDIITGKRSVLDYLLKPILKARHSALRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z383</accession>
    <name>D0Z383_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">GGDEF and EAL domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_000884</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000884"/>
    <dbReference type="EnsemblBacteria" id="EEZ39864">
        <property type="protein sequence ID" value="EEZ39864"/>
        <property type="gene ID" value="VDA_000884"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2199">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2200">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.270.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032244">
        <property type="entry name" value="LapD_MoxY_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042461">
        <property type="entry name" value="LapD_MoxY_peri_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16448">
        <property type="entry name" value="LapD_MoxY_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="154"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="3">
        <location>
            <begin position="174"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="4">
        <location>
            <begin position="265"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="2">
        <location>
            <begin position="407"/>
            <end position="644"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="644" mass="72714" checksum="4758C94EB5BB2E4F" modified="2010-01-19" version="1">MVMSLYRKILLWMLVVFFVLISAVFAVQFNTTKDYLQTQQSTELDNAISAVGLALAPYLENKDYVAAESVINATFDSSFYSAVELKTLDGKTSIARQYPIEIIDVPQWYMNFISIEPVTKTTTLASGWMQLAHLTVTSSPANAYIQLWHATTQLLLGFIITIILAAIILALILRNVLTPLKHIQKQAQLISSNQFDKPLPIPAVKELKDVVHAFNHMSAQLKKYFEQQAAEADKLRIRAYQDPVSGLANRTFLMSQLQSWLEQDSCGGFALLKADIIEDTYTHQGYELGDQQVQTLANRLKELSSDYYTIARLNQAEFILIAPEADEDELKMLGRQMLNMTSELNSDPLNLAPVHAAVGIVMKNQEDTISTLLTQADNALTIAHQQPNEPIAIIQSENNQKLNLIGKQQWKYLVDEAIANRQIRFNYQNAVDLNGEVLHQEVFAYIDKAGKYISASQFLTALEQLNAGTSFDIFVLDAIFEQVLHNNIKQPIAINITQSSINDNSFIRWVSNKTESYPSLKDKIYFELPEISFIKNPHNVGLLCEILHRNGFQFGIDKFGYNFGSTGYLSQFRPAYVKLDFTYTNQVDDEVKADALTSITRTAQNLGITVIASRVETEAQKDKLSEFMINGFQGYITDNFKQER</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3D4</accession>
    <name>D0Z3D4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000935</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000935"/>
    <dbReference type="EnsemblBacteria" id="EEZ39915">
        <property type="protein sequence ID" value="EEZ39915"/>
        <property type="gene ID" value="VDA_000935"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5032627">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="62" mass="7031" checksum="B1F6BDA15549CEBD" modified="2010-01-19" version="1">MKFLLNANCESNNTLLSVLGYQEFAKDVLFDFLEANQQNIIIEFNSQRQNATDEIQLAAAGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3E3</accession>
    <name>D0Z3E3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein BatA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000944</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305794.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000944"/>
    <dbReference type="EnsemblBacteria" id="EEZ39924">
        <property type="protein sequence ID" value="EEZ39924"/>
        <property type="gene ID" value="VDA_000944"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="736429at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01467">
        <property type="entry name" value="vWA_BatA_type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033881">
        <property type="entry name" value="vWA_BatA_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00092">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="298"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="2">
        <location>
            <begin position="84"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="321" mass="35911" checksum="96AD1EC41F78D9C2" modified="2010-01-19" version="1">MFEFAWLWAWLLLPLAYLVYRFSKPVTEPAAIHLPLLPDNIGSSQPKNRLKQILMALLWVSLVCALARPVWYGDPIEIKPDHRDMMLAVDLSGSMAIKDMQTQSGQSIDRLTAIKHVLSNFIEKRKGDRLGLVLFGDHAYLQTPLTFDRHTVEQQLDRTVLGLVGQSTAIGEGLGIATKTFIKSKAPQRVIILLSDGANTAGVIDPLEAAKLAKESGVTIYTVGIGADEMLQRSIFGVQKVNPSQDLDEKTLTKIAQMTGGKYFRARNPQELDKIYQIINQLEPVNNAQQTWRPRDELFRYPLTVALVLSLIIAILRKRNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3L3</accession>
    <name>D0Z3L3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hypothetical transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001014</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305990.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001014"/>
    <dbReference type="EnsemblBacteria" id="EEZ39994">
        <property type="protein sequence ID" value="EEZ39994"/>
        <property type="gene ID" value="VDA_001014"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="750230at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="3"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="292" mass="33144" checksum="8C085C0E9649A2B0" modified="2010-01-19" version="1">MNWTIDQLIAFVSAVEAGSFSAAARRLGKAQSRVSTAIAHLEADLGIELFDRSGRLPILTETGQQLYEDAKGILQQCERLQAKAGHATQGQEIALTIAIDEAVPVVTFEDFFTQLASQFPDLKLTIINGSQDDIALWVDEGRADVGMMFYLNELPSRLEFTLINDFKQTLVVAKEHPLAMYPIPTIEQLNQYRQLVIRDRIGNRSETPISSRHWHIDSYYHITALVLRNIGWALIPEHVARAEWYIDDLVELSTDNIFDSLWVEMGIVKRRDKAKGPVMVWIYQQIRALFDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3L5</accession>
    <name>D0Z3L5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001016</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305995.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001016"/>
    <dbReference type="EnsemblBacteria" id="EEZ39996">
        <property type="protein sequence ID" value="EEZ39996"/>
        <property type="gene ID" value="VDA_001016"/>
    </dbReference>
    <dbReference type="GeneID" id="57342503"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1661500at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="9"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="312" mass="35169" checksum="90FB011F50883887" modified="2010-01-19" version="1">MLPERASRMAIFHTLVVSGSFTQAALTLGVSTSHVSKQLGLLEADLEVKLVQRTTRSFTLTEEGVQYAKYCAKLVNTIQDADAMVGDVRNEVSGVLRLGLSKSFGTMHIIPAIEHLRKQFPELHVEVSLFDHKANMVEDGLDLWITNVENIPEGYVAQKLADTRFIVAASPEYLLHHPAPTHPNELQEHNCLTYQSRHHSHNTWSFNKGTEGLFVTVSGNYRVDLAEAVRDACISGWGIAYLATYLLTDEFRQGKLIQLLPDWEADQAMHFYAVYPSRKHLPKKISAAISFFKHYIGEPPYWDKALKPLVRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3L7</accession>
    <name>D0Z3L7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001018</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305997.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001018"/>
    <dbReference type="EnsemblBacteria" id="EEZ39998">
        <property type="protein sequence ID" value="EEZ39998"/>
        <property type="gene ID" value="VDA_001018"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG50303N7">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1763734at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008775">
        <property type="entry name" value="Phytyl_CoA_dOase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05721">
        <property type="entry name" value="PhyH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="295" mass="34122" checksum="B444B7F78D1C269B" modified="2010-01-19" version="1">MTCAQDLLRQLSQDGVVVLPNLISKEQLKAMQVIFAQQLNQPNCNTWQGYYQTDRYRLMVDQVLALHPTFVQLAIAPLLYTMVSQYLGDDACLQEAKGWQSLPFNYDFHPLHRDEWYCTEFYQDKLPPKSLKLGCYLQDVKSGSFGYVLGSHLKSNGIEVGERFHQDAKDYAMHKIVGRAGTCFLFDPQGLHQQTYPNNEARNAVFYHYFSPHIRLAKAFIRSGRYNHMLVDISYLKGLSPHQMQFLGLEKGPLQSNLLLPSSRQQTCIIRAGLRAYNEFRYWKQRVIARLSKIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3M3</accession>
    <name>D0Z3M3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001024</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306011.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001024"/>
    <dbReference type="EnsemblBacteria" id="EEZ40004">
        <property type="protein sequence ID" value="EEZ40004"/>
        <property type="gene ID" value="VDA_001024"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502Z8D0">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="875447at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018817" evidence="1">
        <location>
            <begin position="21"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="288" mass="31894" checksum="B045E9672C577123" modified="2010-01-19" version="1">MQRRLIPLLCGLAVSSSAFAQSFSLPIWKEKAEALGYDLPKPIGFNLSYMSLEQGIQVDSIGFSGLHLPNFIRGIDMQAEKGKQTSEVVTLRADMWLFPFLNVYALAGKMTGKSETSVNYAVSVKPLLPGRPDHKIKGRIDNFSLDLDGYLYGGGIVLAGGYENWFGLVDASYTQTQLTVIDGNIDAWVISPRVGYDFHKLGVPLRIWGGAMYQDVEQSLSGQLSELGLPSALNPIVKDGEFHIEQRLTTEWNPIMGAQYQINPNLNLLAEFGFGDRQSAFVSIDFRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3P0</accession>
    <name>D0Z3P0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Adenylosuccinate synthetase</fullName>
            <shortName evidence="7">AMPSase</shortName>
            <shortName evidence="7">AdSS</shortName>
            <ecNumber evidence="7">6.3.4.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">IMP--aspartate ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">purA</name>
        <name evidence="8" type="ORF">VDA_001041</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>GTP + IMP + L-aspartate = GDP + 2 H(+) + N(6)-(1,2-dicarboxyethyl)-AMP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:15753"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57567"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="6.3.4.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="7">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Purine metabolism; AMP biosynthesis via de novo pathway; AMP from IMP: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the adenylosuccinate synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.4" evidence="7"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306060.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001041"/>
    <dbReference type="EnsemblBacteria" id="EEZ40021">
        <property type="protein sequence ID" value="EEZ40021"/>
        <property type="gene ID" value="VDA_001041"/>
    </dbReference>
    <dbReference type="GeneID" id="57343489"/>
    <dbReference type="eggNOG" id="COG0104">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="232152at2"/>
    <dbReference type="UniPathway" id="UPA00075">
        <property type="reaction ID" value="UER00335"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004019">
        <property type="term" value="F:adenylosuccinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044208">
        <property type="term" value="P:'de novo' AMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd03108">
        <property type="entry name" value="AdSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00011">
        <property type="entry name" value="Adenylosucc_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042109">
        <property type="entry name" value="Adenylosuccinate_synth_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042110">
        <property type="entry name" value="Adenylosuccinate_synth_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042111">
        <property type="entry name" value="Adenylosuccinate_synth_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001114">
        <property type="entry name" value="Adenylosuccinate_synthetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11846">
        <property type="entry name" value="PTHR11846"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00709">
        <property type="entry name" value="Adenylsucc_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00788">
        <property type="entry name" value="Adenylsucc_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1 7 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 7" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="IMP binding" evidence="7">
        <location>
            <begin position="13"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="region of interest" description="IMP binding" evidence="7">
        <location>
            <begin position="38"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="297"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="13"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="41"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="12"/>
            <end position="18"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="40"/>
            <end position="42"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="301"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="303"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="329"/>
            <end position="331"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="407"/>
            <end position="409"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ40021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="418" mass="45684" checksum="E5E3DF8CDE0FD773" modified="2010-01-19" version="1">MSSIVVVGANWGDEGKGRIVDFLAENASASVRFQGGNNAGHTVVNDFGTFKLHQLPSGVFNPDCIAVLGPGMVISPELLSQEIAEVKQSGVEIKLCISDRATFCLPLHALEDTLEEARLADRAYGSTRQGIAPAYGDRVMKKGILVGWLKQPEVLEERIQFWLDWKLPQLKALYPSFEFTQTAAEMTQWLLDVSAPWRDAICNVTVPLKEIQAKDGNLLFEAQLGAGRDLVYGEYPWTTSSNVTSAYAGLGGGLPALRPERVVAVAKAFSSSVGTGTLITAMEEQDAFREKANEFGATTGRPRDMGYFDAVATRNGVELQAATEVALTKIDCLTGLKDLKICVAYDGNHSENPIWPQTASLAPVYEQMESWEEDITGCRTFESLPKAAQQYVLRIEELMGVPVSMISVGPEREQMILR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-06-02" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3R0</accession>
    <name>D0Z3R0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001061</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001061"/>
    <dbReference type="EnsemblBacteria" id="EEZ40041">
        <property type="protein sequence ID" value="EEZ40041"/>
        <property type="gene ID" value="VDA_001061"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4289">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016624">
        <property type="entry name" value="UCP014753"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35339">
        <property type="entry name" value="PTHR35339"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10022">
        <property type="entry name" value="DUF2264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="512" mass="58837" checksum="AC7939CFB2FAE8B4" modified="2010-01-19" version="1">MTTKTPQTPTSAPKAETKSHIDSIKHITATERPVVPYEHPDAKMYWHLFKQRLVRLKVKKPRYAKHDHHIQQLFQQEQDLRVLCDSLSQYVTEAFCHYSVWDHSHAYYPGRPSQQSARTDAVEGVSRVLPTLAAWLHFSNQTQMTTLDGQSIDIASLLSQAFLAGTNPTHPGYWGTLHNCDQRICESADLALALWLSKEWVWQHYSAPEQQQIVQWFKQVNSLITVDNNWHLFPLTVQVVLKALTGEELVDHDKYERIKVFYVGDGWFRDGAKGNYDYYNAWGFHYSLYWLDQIDPSFDPDFIRQSLSDFVSGYRYFFTPQGLPFFGRSACYRLAAAAPLLMAIDQNSSALSVGEAKRAFRLNLTYFVGNGAMQYGAPTQGLFQDDGRLVDNYSGPASSFWSLRALNIALFIGNRCDLWHAKETPLMIEQQGYDFDIPAIQANIKGVFETKEIVVTFRHEYTEQQTPLSRRLESQSYLNKALELVLGRAERPKNNLLRKGITSYSSKMSHFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3R7</accession>
    <name>D0Z3R7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Altronate hydrolase</fullName>
            <ecNumber evidence="4">4.2.1.7</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001068</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UxaA family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.7" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306137.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001068"/>
    <dbReference type="EnsemblBacteria" id="EEZ40048">
        <property type="protein sequence ID" value="EEZ40048"/>
        <property type="gene ID" value="VDA_001068"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2721">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="889365at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008789">
        <property type="term" value="F:altronate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007392">
        <property type="entry name" value="Gal/Altron_deHydtase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04295">
        <property type="entry name" value="GD_AH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 4" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GD_AH_C" evidence="3">
        <location>
            <begin position="4"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="391" mass="41666" checksum="BC197DC1849568DC" modified="2010-01-19" version="1">MTMTFKGFPRPNGTFGIRNNVMIVAIDECCEGIARNISKEIDDSVVVTNHYTCMYGGNEEMIDTIIHTATNPNIAGVLVIAMGCGSIDPEMVAEPIRKEGLPVHTLTVIKNKGTIETIKDGLVLAKELKAYADSVERIDAPISALRIGIKCGGSDTSSGLASNPSVGAASDKLVDMGATTMAGELLELLGCEEILKARSVTPEVGSKIERLIAEDLKRWHVIEGTETMSIGNSVGGLTTIDEKSQGAMHKTGTQPIQDCLRINHIHREKPTKPGFYLTETTMLCGGAAMHFASLGCQLILWTAGAAGFNNSIVPVIRVSGNSALITADMDINACGIMDATDTIDNVSNKIIDKVFAVADGLPTNLEGIGFAYASLYQKDQRLEHVIGICPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3X5</accession>
    <name>D0Z3X5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0597 protein VDA_001128</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001128</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0597 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306290.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001128"/>
    <dbReference type="EnsemblBacteria" id="EEZ40106">
        <property type="protein sequence ID" value="EEZ40106"/>
        <property type="gene ID" value="VDA_001128"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3681">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1326279at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01845">
        <property type="entry name" value="UPF0597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005130">
        <property type="entry name" value="Ser_deHydtase-like_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021144">
        <property type="entry name" value="UPF0597"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30501">
        <property type="entry name" value="PTHR30501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03313">
        <property type="entry name" value="SDH_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006054">
        <property type="entry name" value="UCP006054"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SDH_alpha" evidence="2">
        <location>
            <begin position="92"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="434" mass="45096" checksum="79F29C5DB2B42092" modified="2010-01-19" version="1">MKKHLWNGFISVVKRDVVPALGCTEPVSVALAAAIAMEKLKQRGVTQIDAIRAQVSPNLMKNGMGVGVPGTGMVGLPIAAAVGAIAGDSQAQLEVLKNITEQDVKLGKALIDNGNVAVTVADVTNILYAKATLYSGEHFVSVTIADSHTQVIAIEEDGITTFTAQKDASAQKASAAENPFIEAIAEDIYDFAMNAPLEDIRFIEQAYELNDALSIEGLTGKYGLQIGATFQRNVDRGLLSGGLLTEVLCRTSAASDARMDGAMKPAMSNSGSGNQGIAATMPVVAVADFIKANKEQQIRALMLSHLMAIYIKSHQNKLSALCGATTASMGAVAGMTWLLGGNFPQISSAICSMIGDIAGIICDGAKTSCAMKVSSSASAAVKAALMALDGIRVTGNEGIVADDVDTSIRNLSALANGAMTQTDVQILDIMVNKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3X9</accession>
    <name>D0Z3X9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001132</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40110">
        <property type="protein sequence ID" value="EEZ40110"/>
        <property type="gene ID" value="VDA_001132"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="47" mass="5192" checksum="7F6F84CA2CC1A389" modified="2010-01-19" version="1">MYLEFDGVNEGKSDGDGFDGEYDGVINAYKVRLSSKAIPNNCKIHSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3Z1</accession>
    <name>D0Z3Z1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Bifunctional protein PutA</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="2">Proline dehydrogenase</fullName>
                <ecNumber evidence="2">1.5.5.2</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="2">Proline oxidase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="2">Delta-1-pyrroline-5-carboxylate dehydrogenase</fullName>
                <shortName evidence="2">P5C dehydrogenase</shortName>
                <ecNumber evidence="2">1.2.1.88</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="2">L-glutamate gamma-semialdehyde dehydrogenase</fullName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_001144</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Oxidizes proline to glutamate for use as a carbon and nitrogen source.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>H2O + L-glutamate 5-semialdehyde + NAD(+) = 2 H(+) + L-glutamate + NADH</text>
            <dbReference type="Rhea" id="RHEA:30235"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58066"/>
            <dbReference type="EC" id="1.2.1.88"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a quinone + L-proline = (S)-1-pyrroline-5-carboxylate + a quinol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23784"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17388"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.5.5.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid degradation; L-proline degradation into L-glutamate; L-glutamate from L-proline: step 1/2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid degradation; L-proline degradation into L-glutamate; L-glutamate from L-proline: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the C-terminal section; belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the N-terminal section; belongs to the proline dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.5.5.2" evidence="2"/>
    <dbReference type="EC" id="1.2.1.88" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306333.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001144"/>
    <dbReference type="EnsemblBacteria" id="EEZ40122">
        <property type="protein sequence ID" value="EEZ40122"/>
        <property type="gene ID" value="VDA_001144"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0506">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4230">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="14333at2"/>
    <dbReference type="UniPathway" id="UPA00261">
        <property type="reaction ID" value="UER00373"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003842">
        <property type="term" value="F:1-pyrroline-5-carboxylate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004657">
        <property type="term" value="F:proline dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006561">
        <property type="term" value="P:proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010133">
        <property type="term" value="P:proline catabolic process to glutamate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025703">
        <property type="entry name" value="Bifunct_PutA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005933">
        <property type="entry name" value="Delta1-pyrroline-5-COlate_DH-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029041">
        <property type="entry name" value="FAD-linked_oxidoreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024089">
        <property type="entry name" value="PRODH_PutA_dom_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024082">
        <property type="entry name" value="PRODH_PutA_dom_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002872">
        <property type="entry name" value="Proline_DH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01619">
        <property type="entry name" value="Pro_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14850">
        <property type="entry name" value="Pro_dh-DNA_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000197">
        <property type="entry name" value="Bifunct_PutA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51730">
        <property type="entry name" value="SSF51730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81935">
        <property type="entry name" value="SSF81935"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01238">
        <property type="entry name" value="D1pyr5carbox3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="1 2 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0642">Proline metabolism</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Pro_dh-DNA_bdg" evidence="7">
        <location>
            <begin position="74"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="Pro_dh" evidence="6">
        <location>
            <begin position="199"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="domain" description="Aldedh" evidence="5">
        <location>
            <begin position="580"/>
            <end position="1034"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="813"/>
        </location>
    </feature>
    <feature type="active site" evidence="3 4">
        <location>
            <position position="847"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR000197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000197-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ40122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="1047" mass="116453" checksum="498E5E062D601BD0" modified="2010-01-19" version="1">MLDVNAVLAPTYLSQSTLLDHWERISPLYCIDEDLWLTELLKLVRPTSTENDEITTRAKDLVGQVRADRRSVQMIDALLLEYSLDTDEGITLMCLAEALMRIPDTVTADKLLRDKLSVANWYAHLQHSNSVFVNASTWGLMLTGKVATWHNIEGDSPTQAMTRLVNKLSEPVVRKAMQQAMKIMGHQFVLGRTIDEALDHASEDHRQGYLFSFDMLGEAALTKLDANKYYHDYLSAIEHVAQQKTDSSQQDKESFSVSIKLSALHPRYEMAQAERVLDEMYQSVLDLLIRARQLDVAITIDAEESDRLELSLLLFQKLYQTPELIGWGGFGLVVQAYSKRALAVLVWLAALAQQQGDQIPVRLVKGAYWDSEIKLAQQRGIAGYPVFTRKEATDCAYLACARFLLQDHMSPLIYPQFATHNAHTIAAIEVLAKDRRDYEFQRLHGMGKTLYQKVRAARSQPVRVYAPVGSHKDLLPYLVRRLLENGANSSFVHRLIDAQCDIEQLVIHPYEQLMSRHSLANNAIALPPNLFAPLRKNSQGVSLDIASEQTLLMAEVALYSKGLWQANSIIDGKKALSTHPINVTSPFDNKVIVGERYDATPQEIESAIKAAAHGFLSWSVRPVEERCQCLLKLADLLEIHQAELIALCQKEAGKTWQDSIDEIREAVDFCRYYAVQAETLFHEPQSANDYLGRSCERQYQAKGVFVCISPWNFPLAIFLGQITAALVSGNSVIAKPAEQTSLIATRTIELMFEAGVPSHAIQLLIGSGQSIGPYLLSQSAIAGVAFTGSTQTAHHITKTLAERECLPATLIAETGGLNAMIVDSTALPEQVVRDVIRSSFASAGQRCSALRVLYIQDDISQRLISLLQGAMEELVIGDPQYYQTDIGPVIDQLAYDRLTHHIQSLQSNHQLLYQCQLNETASNGFFVPPTLAQIGSITELTQEHFGPILHVVSYKATELDQIITDINSMGFGLTLGIHSRNEATYHAIAQQVEVGNCYINRDQIGAVVGVQPFGGHGLSGTGPKAGGPHYLYRFVYESLIYSSEMEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z436</accession>
    <name>D0Z436_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hypothetical Ap4A phosphorylase II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000292</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303960.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000292"/>
    <dbReference type="EnsemblBacteria" id="EEZ39274">
        <property type="protein sequence ID" value="EEZ39274"/>
        <property type="gene ID" value="VDA_000292"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4360">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1314021at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003877">
        <property type="term" value="F:ATP adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009163">
        <property type="entry name" value="Ap4A_phos1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043171">
        <property type="entry name" value="Ap4A_phos1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045759">
        <property type="entry name" value="Ap4A_phos1/2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38420">
        <property type="entry name" value="PTHR38420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19327">
        <property type="entry name" value="Ap4A_phos_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000846">
        <property type="entry name" value="ATP_adenylyltr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="SSF54197"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ap4A_phos_N" evidence="2">
        <location>
            <begin position="2"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000846-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="268" mass="30742" checksum="7BDD2CDDDF6548DF" modified="2010-01-19" version="1">MLWSLAEHISEKALQEGALFPLTDNDTLVEQDGITYVGNIITGNMKKKYSPDVANHDPFLPPYNPETYLGSMGREHVCLLNKFPIIVPHLLVCAKQYVPQTSPLTESDFSAWIKAFTRDDVLGFFNSGHIAGSSQMHRHMQLVRTHIPLESRIVNKQLPFKHALFQFDKLDPDFLYQCYQSAMVELDLYVLSHSNEYQECNPYNILLTQHWMLVIPRSKNQVEDISGHGINFSGRFLVGSDEQLSWLREYGFIHFLTECCQKTSVSND</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z439</accession>
    <name>D0Z439_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Hypothetical permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_000295</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303970.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000295"/>
    <dbReference type="EnsemblBacteria" id="EEZ39277">
        <property type="protein sequence ID" value="EEZ39277"/>
        <property type="gene ID" value="VDA_000295"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3127">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="127265at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038766">
        <property type="entry name" value="Membrane_comp_ABC_pdt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30287">
        <property type="entry name" value="PTHR30287"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="257"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="301"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="351"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="395"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="419"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="707"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="756"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="791"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="8">
        <location>
            <begin position="287"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="8">
        <location>
            <begin position="738"/>
            <end position="821"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ39277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="825" mass="91669" checksum="237A63C3970CBFAE" modified="2010-01-19" version="1">MNKSMVSSSNIFFLLRWSLREIRQGQLWLVTLALSLIIACVFALSALVARIEGIITEQGRSALTADLVLVSANPIDDSIIKLAHNYQLITAQQTRFGTMAFSDSAMQLVSVKAVSDNFPLKGNLILGASSDTTQYHHVVPHQLWLSERLFSLLDVNVGDSLDIGDTTLTISGRIVEDPELSFNPFSQMPSVLISHSDIEATGAIQPGGRISYRWYFSGTQANLDQFRSQVSLTASQRWQTEREAGRSGDFITRAEQYLSLTLVLVILMAAATLVLTCQYYCSSRKASVAMMKSLGAQKAFLWRWLLIQIALLFVFAACIGLSVGIALEWLLRYPLQSLLPHSIPTIGWQPAILSLVVAFCISLPALGIPLIRLVNIKACAAIDGNETQMIQSHRFTFSWLLLLVPVITAVAWINTNIFVWLTLLGLLLLLGLLALFGMAALHMMGRVRLNSSYQLAVRRINRSKVKAATQLAALTSSLMLVAVIALLRQELLSDWQQTLPENAPNVFAVNIAPSQQQQYLQDLDQLGLERSSGYPVVRGRLTAINDRFFGKEEPDKDNAAQSPANDDEALNRELNFTWTQVLPTHNQLVQGEWGNRVDGVSVESGIAKRLGIQLGDHLTFSVGSFPFTAVVTSIRDVEWRNMKPNFYFIFSPELLASYPAAWLVSFRIESDQNQQLNQLAEQYPTVSLLDLRLMANRIQGLLSQVSWSLSVLAGLGVVSGLMLIMTLLRLSLSERQLEVQLYRTLGASRKRISDTLWYEFGTIALLGGVIAAGCSEFVVGILLIYGFELPFYPHISIWFILPLFALLLVYCVTRSQINQLLKPLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4D5</accession>
    <name>D0Z4D5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Glutathione-regulated potassium-efflux system protein kefC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_000391</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304234.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000391"/>
    <dbReference type="EnsemblBacteria" id="EEZ39373">
        <property type="protein sequence ID" value="EEZ39373"/>
        <property type="gene ID" value="VDA_000391"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0475">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="941006at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015299">
        <property type="term" value="F:solute:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004771">
        <property type="entry name" value="K/H_exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003148">
        <property type="entry name" value="RCK_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02254">
        <property type="entry name" value="TrkA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00932">
        <property type="entry name" value="2a37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51201">
        <property type="entry name" value="RCK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0050">Antiport</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="85"/>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="113"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="146"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="200"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="257"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="287"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="313"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="344"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="377"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="RCK N-terminal" evidence="9">
        <location>
            <begin position="421"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="609"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="609"/>
            <end position="624"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ39373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="654" mass="71599" checksum="7B4B8660A537BDE0" modified="2010-01-19" version="1">MTGYFLQAFIYLFAAVIAVPIAKRLGLGSVLGYLIAGVVIGPVIGLVGSETTTIQHFAEFGVVMMLFLVGLELEPRMLWDMRHRLIGLGGLQVGLSTLVVMGIAMAFGIGWTIALTIGLIFSLSSTAIVLQTFNEKGLSKTEGGRTAFSVLLFQDIAVIPMLALIPLLALPDLVAKAQSAAQQVAEHHDSLSLVAGLPGWAYALVVILAIVGVVVGGHYLSRPLFRFVASSGLREIFTATALMLVIGIAALMSLVGLSPALGTFLAGVVLANSEFRHELESNIEPFKGLLLGLFFITVGAGIDFNVLFDQFGIVIGMTLGVMLIKALVLLLLSFIFKVKGRDRWLFALSLAQAGEFGFVLLSYTVQNHVLPVEISQTLSLVVALSMFLTPGLFILFDRVIEPRFAESINDREADTIDEEGTVVIAGIGRFGQIVNRLLVANGIKTVVLDHDAGLIENMRQIRIKSFYGDATRDDLLHSTGIAEAKVFVVAIDDKERAIDLVKHVKHTYPKVKILARAYDRGHHYSLRNAGADYVISETYRSALALGTEVLKEMGVHPFKAEQQKAAFVETEAQSKDILFQTWKESTEDDRFNASYRELFMQLEDALSEAMKRERGDRHSKSERGWTPPPKGYDDVVEQIQAEKEEEEQEQKSAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4I7</accession>
    <name>D0Z4I7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">VDA_000445</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304386.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000445"/>
    <dbReference type="EnsemblBacteria" id="EEZ39425">
        <property type="protein sequence ID" value="EEZ39425"/>
        <property type="gene ID" value="VDA_000445"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1455">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5001">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008982">
        <property type="term" value="F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003352">
        <property type="entry name" value="PTS_EIIC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004501">
        <property type="entry name" value="PTS_EIIC_3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02378">
        <property type="entry name" value="PTS_EIIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51105">
        <property type="entry name" value="PTS_EIIC_TYPE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="113"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="153"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="254"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="287"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="313"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="350"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="domain" description="PTS EIIC type-3" evidence="10">
        <location>
            <begin position="1"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="9">
        <location>
            <begin position="422"/>
            <end position="673"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ39425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="673" mass="75174" checksum="1DE80C3FB4449BD1" modified="2010-01-19" version="1">MTLSQLLSNLSSNKYLVAVSNVFLMALPISLISTFCDLTAIFSQKMGWDTLSITTGYVGQMIAQMFPILINIYLSSYLASIKRIPKSVAIATSLVVFFLVSQQWNLISVAVPLPNSFALALLSAYLSCHLIFKAQNLPIFRVDPFTSAIDNSGHIISICAVSIIVMVGVSTGIHCLIESIDFHFSILPELNPLSFTDGLLYEFLRGVFWSFGINGHNVLHMYKTELYSLTTANIADWQNFGVDLNIVSTNFYDFFTGIGGSGNTLSLVLCILLFARSRNYRTLAKTVLILSLFNINEPILFGIPVIFNPIMIIPFLLVPMVSFVVAYGAIAIGLVPPLSTVQSWIMPPLVSGYLGTGAISGALLQLIIIIIGIGLYYPFFKFMDKRSLGVDVTSIFNNRFFTSDEIEAKSKLTSFIPSLHKNLQAQREVEKLQQEGEFILYFQPQVDIHSKKVVAMETLLRYRDSDGNIRPPTFLSSFTQLGLMPELDFWVIERSVQMMTPLAEKNPDFKLSINVSPTTVLTKDFVFNFAKIVNKSSLDFHQLEVEITEELLVQDENKTSEIIKELQLLGVSVALDDFGTGYSSLAYLSRFEFNKIKIDRSLVLNLNSIKGQELFSVVVQLGKVANAKIIVEGVETDDELHFISLLGVRYVQGFYYYKPMPLEEIVAQKLIEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4J4</accession>
    <name>D0Z4J4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000452</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304405.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000452"/>
    <dbReference type="EnsemblBacteria" id="EEZ39432">
        <property type="protein sequence ID" value="EEZ39432"/>
        <property type="gene ID" value="VDA_000452"/>
    </dbReference>
    <dbReference type="GeneID" id="57342620"/>
    <dbReference type="eggNOG" id="COG3930">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="504489at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012656">
        <property type="entry name" value="CHP02421_QEGLA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012548">
        <property type="entry name" value="DUF1704"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007709">
        <property type="entry name" value="N-FG_amidohydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31817">
        <property type="entry name" value="PTHR31817"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08014">
        <property type="entry name" value="DUF1704"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05013">
        <property type="entry name" value="FGase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01154">
        <property type="entry name" value="DUF1704"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02421">
        <property type="entry name" value="QEGLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="660" mass="75732" checksum="519AAD5E346DEF44" modified="2010-01-19" version="1">MLQLSESQVLEKIQHLVPFEAQLDDGSLTIRISEYQPYIATAIHHGHNLREELLAKCALSEEERYFEEDPFTGDFITSLPIILQGEDSRYEYDLNRAPDNCIYEDAWGKEVWTESLTEQERQTTLEKHARYYRILKCLIETLENKFGLCLLYDIHSYNYQRIEREVPTFNLGTEQVNCRRWRKELDVLLEHLNAIELPNIDVVANENDVFKGMGYQATFVKENFSNTLIMPLEVKKVFMNEQAGDAYPLVIDKLKESMKTAITEHAAFTINKRTKAKGLTSSDLLASSLSKEAIKLDRQLYKIARGLNTLSYINPTNLKQEKRRFLSKPHTYVPQFTYRQLDLDPYKFREQLYRLPVEDIRDADVQKMYRRVIDQLAVRIDLLCTIGTDEFLYNSLRYYGQPDERDIANAKFILHACEYAKQEEATINAAGAIQAFKEAAADYGLPCKIVMSKQLIARALVSGKTVKVNPNSTFSKPDLEALIHHELGVHLVTSVNAERQPLRVLQLGLPGNTHTQEGLAILCEHLSGNFPLHRLKTLALRVVAVDMMVNGESFNDTFNTLKHDYDVSDDEAFTVTARAYRGGGFTKDYLYLRGLKDAIKAYQEEDLTSLFIGKTGFEFKPVLDELIERGILKQPEFLPKALSMNAELDPVMEFMLSSIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4K7</accession>
    <name>D0Z4K7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Formate acetyltransferase</fullName>
            <ecNumber evidence="8">2.3.1.54</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Pyruvate formate-lyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">VDA_000465</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>acetyl-CoA + formate = CoA + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:11844"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.1.54"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Fermentation; pyruvate fermentation; formate from pyruvate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.54" evidence="8"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304438.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000465"/>
    <dbReference type="EnsemblBacteria" id="EEZ39445">
        <property type="protein sequence ID" value="EEZ39445"/>
        <property type="gene ID" value="VDA_000465"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1882">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="116406at2"/>
    <dbReference type="UniPathway" id="UPA00920">
        <property type="reaction ID" value="UER00891"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008861">
        <property type="term" value="F:formate C-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01678">
        <property type="entry name" value="PFL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005949">
        <property type="entry name" value="Form_AcTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019777">
        <property type="entry name" value="Form_AcTrfase_GR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001150">
        <property type="entry name" value="Gly_radical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004184">
        <property type="entry name" value="PFL_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01228">
        <property type="entry name" value="Gly_radical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02901">
        <property type="entry name" value="PFL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01255">
        <property type="entry name" value="pyr_form_ly_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00850">
        <property type="entry name" value="GLY_RADICAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51149">
        <property type="entry name" value="GLY_RADICAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51554">
        <property type="entry name" value="PFL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8 11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0313">Glucose metabolism</keyword>
    <keyword evidence="11" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 7 8" id="KW-0556">Organic radical</keyword>
    <keyword evidence="11" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PFL" evidence="10">
        <location>
            <begin position="4"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="domain" description="Glycine radical" evidence="9">
        <location>
            <begin position="632"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="modified residue" description="Glycine radical" evidence="7">
        <location>
            <position position="740"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU368075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ39445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="765" mass="85943" checksum="611EA3AFD4874692" modified="2010-01-19" version="1">MTIPTTDMLDAWTGFSAGEWQKSVNTRDFIQTNYTPYEGDESFLADVSDSTTALWNQVLEGIKEESRTHAPIDFDTDLPSTIISHDAGYINKDLEKIVGLQTDKPLKRSIIANGGIRMVKNSCEVYGRQLDPSVEKIFTEYRKTHNKACFDLYTKEILACRKSGIITGLPDAYGRGRIIGDYRRLALYGIDYLKADKKEQFDSTQAFLEQGQDLEKTLRLREELADQFQALEDIRQMGLKYGIDMSLPARTAQEAIQFTYFGYLAAVKSQNGAAMSLGRTSTFLDVYIQRDLENGLINEQQAQEMIDHFIMKLRMVRFLRTPEYDSLFSGDPIWATEAMAGMGVDGRTLVTKTTFRYLHTLHTMGPAPEPNMTILWSEQLPLSFKKYAAKVSIDTSSVQYENDDLMRPDFNNDDYAIACCVSPQIVGKHMQFFGARANLAKALLYTINGGIDEKSKAQVGPKTDKVVDDILDFDTLMPRFDSMLDWLATQYVTALNIIHYSHDRYSYEASLMALMDKDVYRTMACGIAGLSVVADSLAAIKYATVKPIRDEDGVAIDFEISGDYPKFGNNDARVDDIACDLVERFMKKIQKMHTYREATPTQSILTITSNVVYGKKTGNTPDGRRAGMPFGPGANPMHGRDEKGAVASLTSVSKLPFAYAKDGISYTFSIVPNALGKDEETQKQNLAALMDGYFHHEAHGNHETIEGGQHLNVNVLNRDMLLDAVEHPEKYPQLTIRVSGYAVRFNSLTREQQQDVISRTFTDKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4L0</accession>
    <name>D0Z4L0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Hypothetical chitinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_000468</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000468"/>
    <dbReference type="EnsemblBacteria" id="EEZ39448">
        <property type="protein sequence ID" value="EEZ39448"/>
        <property type="gene ID" value="VDA_000468"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3325">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3979">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003610">
        <property type="entry name" value="CBM_fam5/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036573">
        <property type="entry name" value="CBM_sf_5/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02839">
        <property type="entry name" value="CBM_5_12"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00495">
        <property type="entry name" value="ChtBD3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51055">
        <property type="entry name" value="SSF51055"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54556">
        <property type="entry name" value="SSF54556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3 5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GH18" evidence="6">
        <location>
            <begin position="66"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="813" mass="88184" checksum="7560DF2F84FFD4AE" modified="2010-01-19" version="1">MTLLKLWFRAVWLNSGDSVSHIIFNCKRGVQGMKKGHCLTKIAGVVASIMMAGGITSVQAAPSHDKNVIGYITQWEAWKGTNAGFSVKGEATHLNVDMDIYSILNFSFFGVAKDGSLHSGDLRNKSIYQPGAVQEPGPLLHPDVYSSWDFHILWGELEYIHQYPNDEPWDAENLKKVQEQGFVKHGNGWKHEPTGITGQYPIPLKKAGGAPGLIDLAHEKGVKVMASLGGWSMSKHFPEMARDEAKKARFLADVDKLMALGFDGIDIDWEYPGHGGMNFQGSPDDFANFEQLMEDIRKRIGPDKLLTAAFAASTAKLEGFNWPRLVASMDYFNMMTYDLNGGWSNVTGHNAPLYPYPEEEYAGLDLDTLRIWMAEKGIPSDKINFGAAFYGRGVQTTESTAYLGAPTDKRMVNMSVDGPLMSSVDLDNWKEFEGQPNYNYLKKVAGWEHKWDDNAQVPYAIKGKYFLSYDDVPSIKKKAQYIVDNELGGVIVWQVHGDIECKGTFINHGSKLKECTDLSSPLAEAIDSVFSANTTPNAAPVLTVPDAQNVDATQSISFVVSATDADGDKLTFSATGADIVNNGDGSATVTYIAPNTGIDKQEVVKVTVSDGRKSVSKDVVINVKGTGVVENTPPTLTAPATAEVKSGETLVISVSATDAEGDSLTYTASQGTVTSTTSGADISFTAPVVDADTTVNLVVTVSDGQAEASQSVVITVKAEAASGNTWDPNAVYNTGDTVIYDGVTYTAKWWTQGDKPGASDVWQAFDDGSLKEWSADKVYNGGDQATFEGNTYKAKWWTKGDQPGNPNGPWQLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4N5</accession>
    <name>D0Z4N5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Alkyl sulfatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_000493</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the metallo-beta-lactamase superfamily. Type III sulfatase family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304517.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39473">
        <property type="protein sequence ID" value="EEZ39473"/>
        <property type="gene ID" value="VDA_000493"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2015">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="775108at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018741">
        <property type="term" value="F:alkyl sulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018909">
        <property type="term" value="P:dodecyl sulfate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07710">
        <property type="entry name" value="arylsulfatase_Sdsa1-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038536">
        <property type="entry name" value="Alkyl/aryl-sulf_dimr_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029229">
        <property type="entry name" value="Alkyl_sulf_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029228">
        <property type="entry name" value="Alkyl_sulf_dimr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044097">
        <property type="entry name" value="Bds1/SdsA1_MBL-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036527">
        <property type="entry name" value="SCP2_sterol-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14864">
        <property type="entry name" value="Alkyl_sulf_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14863">
        <property type="entry name" value="Alkyl_sulf_dimr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55718">
        <property type="entry name" value="SSF55718"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018924" evidence="5">
        <location>
            <begin position="20"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="domain" description="Lactamase_B" evidence="6">
        <location>
            <begin position="129"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00033751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="659" mass="73289" checksum="08B86906CB4265BA" modified="2010-01-19" version="1">MKLRLLPLSLVIISSVSYAGTTSYTVTADSKPASSFTIEKNNELKQYLNFDNKEDFTAASKGFIATWPDKTIKDKNGNVVWDFAKFEFVNSDQVLDTVNPSLRRMAELNNIHGLFKVTDGMYQVRGFDLSVMTFVRGEHGWIVIDPLISEETAAAGLKLLTEHVEDLPVTAIIFTHSHIDHFGGVWGVTTKEAVDQGKVEIVAPEGFFEHSVSENVLAGNTMSRRASFMYGNMVEAGPQGKVDGGLGKTTSTGKPGIVEENLEVVKTGETHNIDGVEIEFQMANGSEAPAEFIFYFPQKRVLMASEVMTHTIHNISTLRGARTRDANAWAGYIDETLDLFAKKSDIMIASHHWPTWGTSNIVNQLEKTRDMYKYVHDQTLRLANQGYTPNEISASITLPDSLGKEWYNRGYYGTVSHNARATYDFYFGAWWDGNPANLNPLPPEQQAAKYVEAIGGDEKVIEIAKKAISKGEYRWAVTLLNNVTFSNPDNSTARYLEADAMEQLGYQAESGPWRNYYLVGAKELRHGFQPAPTPDTTAIASNMPVYSALESLAIRVMPEQAKGLDMAINLKVAGDKEADGEYALLLSNSVLKTYKGRQLDNPTMTIEFSRDTFVNLVTHQLDLKTAIKKGQFKVSDPKGFTQFMQIFDTFDPKFGVVTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4X0</accession>
    <name>D0Z4X0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000203</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306594.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000203"/>
    <dbReference type="EnsemblBacteria" id="EEZ39187">
        <property type="protein sequence ID" value="EEZ39187"/>
        <property type="gene ID" value="VDA_000203"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5599">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="901171at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006470">
        <property type="term" value="P:protein dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000242">
        <property type="entry name" value="PTP_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003595">
        <property type="entry name" value="Tyr_Pase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00102">
        <property type="entry name" value="Y_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00700">
        <property type="entry name" value="PRTYPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00194">
        <property type="entry name" value="PTPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00404">
        <property type="entry name" value="PTPc_motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="SSF52799"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50055">
        <property type="entry name" value="TYR_PHOSPHATASE_PTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="2">
        <location>
            <begin position="340"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="domain" description="TYR_PHOSPHATASE_2" evidence="3">
        <location>
            <begin position="487"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="572" mass="61743" checksum="CB2ECD0BD8D0C441" modified="2010-01-19" version="1">MPVNNQIQNNLNIQTLTSYIDKASASQSAANANVSYGAMGNAVINTGVSKALNQAAKELIADVKNITLTNDDVKNLYQAQPKAGFALGSQDGVIFVKQIKGELTLEAADILLGAAKRDSAESELANPSSSPTRNTRPNTHPPVSQHGKSEERIYENLQFKVRPQSPVHSPRTNTPPPVPAHAGRSSSPSPAHGSRPSSPVHAVGANSSLDTTKLENTFSAYSDVDIMQKRPSADHKFVAVWPSSKGDGSFGIHLPGARPKRATTLEQAQSIVNNHLQQQSQVQQNHHARNVLASGAQDHREELAQFEQKLGQYKDNISKKNHPEYYHKDPVGTSKENKVDRFGDIGTMLHSKVGYNLNANRITVAGQDVAIATQYPKDSQIEDQLRLLVDNRTPSLTVLTEASQMANPAKGMTDYFSRNLGFNSGLTTQSELTSRDMVVGRNTDGSDLKANVFNLTINIPGEAPFTVPVLHVTNWIDKTAIDAESSNNIATMINGIESDGGAPVVHCRAGVGRTGQIVAAIAMQKVPNSVSAEEVINDMRYSRNDYMGQTAEQRAVIADLARQQGRSVLALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4Z9</accession>
    <name>D0Z4Z9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribonucleoside-diphosphate reductase</fullName>
            <ecNumber evidence="4">1.17.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_000232</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Genetic information processing; DNA replication.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ribonucleoside diphosphate reductase small chain family.</text>
    </comment>
    <dbReference type="EC" id="1.17.4.1" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306679.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000232"/>
    <dbReference type="EnsemblBacteria" id="EEZ39216">
        <property type="protein sequence ID" value="EEZ39216"/>
        <property type="gene ID" value="VDA_000232"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0208">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1384440at2"/>
    <dbReference type="UniPathway" id="UPA00326"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004748">
        <property type="term" value="F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009263">
        <property type="term" value="P:deoxyribonucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01049">
        <property type="entry name" value="RNRR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.620.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012348">
        <property type="entry name" value="RNR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033909">
        <property type="entry name" value="RNR_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000358">
        <property type="entry name" value="RNR_small_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23409">
        <property type="entry name" value="PTHR23409"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00268">
        <property type="entry name" value="Ribonuc_red_sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="151"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ39216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="310" mass="35909" checksum="C5E3C47E790134FB" modified="2010-01-19" version="1">MIVKNKFSLFPIQYEEIWQAYKTHEAAFWTTEELDFAQDLADLAKLTEGEKHFIRHVLAFFAQSEGMINENLLTRFYGEIEIAEARCFLALQAFNEVIHAETYALQLETYIPAVEERERLFNAIENVPTVKRKAEWVMKWISSDKPLTMRLIAFGLVEGLFFAGSFCAIYYFRKRSLLAGLAASNDLIARDEGLHFSFSALLFKTLGQGKVTQQEFEEICREAVSIEKEFVTEALPVDLIGMNAELMCQYIEHTADVIAGLFGFDPIFYAKNPFDYMRLLDMEGKTNFFEKRVTEYKRPQDRQLSFDADF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z504</accession>
    <name>D0Z504_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">OMP_b-brl domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000237</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306695.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000237"/>
    <dbReference type="EnsemblBacteria" id="EEZ39221">
        <property type="protein sequence ID" value="EEZ39221"/>
        <property type="gene ID" value="VDA_000237"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3637">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2059638at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027385">
        <property type="entry name" value="OMP_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13505">
        <property type="entry name" value="OMP_b-brl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003020022" description="OMP_b-brl domain-containing protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="OMP_b-brl" evidence="2">
        <location>
            <begin position="12"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="190" mass="21168" checksum="858762EDAF1B66CF" modified="2010-01-19" version="1">MSNLLRLCIISSLFTASATTWAATPSNVIGLNLGYGGLNASTKLKDFDSSDLFDGDLYYRRMFNENFGLEVGYRSSTGGLGSMLISPLTKITDISYYGPHTDLFAYYPLTGGFSLYGKVGINYYKLDYTYQTNIEGKKQQHRITDSELGGEVAAGVEWRYEWLGFNLGYMYSKSDLIETSGIQFGTSIHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z536</accession>
    <name>D0Z536_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">IncF plasmid conjugative transfer pilus assembly protein TraF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000271</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306785.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000271"/>
    <dbReference type="EnsemblBacteria" id="EEZ39253">
        <property type="protein sequence ID" value="EEZ39253"/>
        <property type="gene ID" value="VDA_000271"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0526">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1630944at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014110">
        <property type="entry name" value="TraF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039555">
        <property type="entry name" value="TraF/TrbB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13728">
        <property type="entry name" value="TraF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02739">
        <property type="entry name" value="TraF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018933" evidence="1">
        <location>
            <begin position="20"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="256" mass="28658" checksum="94FE0165DC154E50" modified="2010-01-19" version="1">MIRTTLLIPLLLISTNLHADNTAQGWRWYNEPRPAVIKPKPITPKRPTATVTTTPPPRTLSATEQMNWFHGYFNEIKNKAVIDPSLANVLDIMRLNHYIDGKTTDFGMTWKQALVTDPSLSYRLKHPTESLARQTQNAQVNAIKANAVRTLAHDGYGLFFVYKGDEPLNKQLAPSIQAFADEYGIELLGVSLDGKKLPSIRHNRLNKGKLKVEAEPALLLVNPNTNTIKPLAYGFISQEELLGRFLNAATNFAPDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z542</accession>
    <name>D0Z542_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chromosome (Plasmid) partitioning protein ParA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000092</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306821.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000092"/>
    <dbReference type="EnsemblBacteria" id="EEZ39076">
        <property type="protein sequence ID" value="EEZ39076"/>
        <property type="gene ID" value="VDA_000092"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1192">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="729012at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025669">
        <property type="entry name" value="AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13614">
        <property type="entry name" value="AAA_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_31" evidence="1">
        <location>
            <begin position="117"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="415" mass="46796" checksum="B68E56E4E6739556" modified="2010-01-19" version="1">MSAIIDSLELVCERMQQEQADLKAVIKERMQINVTDADIEGNVDRLIYNHSLKKKELQELFGLSRVTFNSRIDEATSKKIIGQPIVQGRTHLYNRFDVANMMDYMNFPKYSQRFEPTVIVVENHKGGTGKSTTTVTLATAAALDLNLNARCLVIDLDPQGSTGQNLIHQTDEDSVYMTAIDIALSEFEPDGDFSQYLKEYSYTDLVKAIPFKTHLPNLDVIPAFPSDERFVDCYWGQDSDIQEKLVTVLKEKILPTLKEEYDLIFIDTPPQNSPILWSVNEAADAVLIPVTPREFDFASTSNYMATMPATFRELPSNGKNLKWAKLLPVNFDEKSAHEVKVFDKLLRSAQGHLLSTAIRHSEAFVAASENNRTVLDIKKSEQLCSGKQFDLAMTSITAVYHQFITEIKQLATKGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z565</accession>
    <name>D0Z565_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000115</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39099">
        <property type="protein sequence ID" value="EEZ39099"/>
        <property type="gene ID" value="VDA_000115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="64" mass="7251" checksum="550A46B7E3B71E9B" modified="2010-01-19" version="1">MDNIIQLLNAQYDIAPPKDHDEEIALIYQYLIDKFGDTSTTAFKLHEVLISLAHIAERDGATSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5B1</accession>
    <name>D0Z5B1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000161</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005307019.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000004.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39145">
        <property type="protein sequence ID" value="EEZ39145"/>
        <property type="gene ID" value="VDA_000161"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502Z940">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="633581at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="357"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="415"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="447"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="568" mass="64754" checksum="27D6D908D6C6B97A" modified="2010-01-19" version="1">MTALVRKDFILMEELNKTIVQSLASSFALDFLLFEDKKGGDVATVHNVREHFRGDSSIHLSDSTKQEYASRGDYKPVKQDGNGQIVKDKKGNPIKVDLYHTHSNYIERGRADKKLHQEGKLHDVYRNNNMAYNEGRQLDHIISSHEVHNDPGRVLAGLTGSDIANKNTNFQSTHSYINNLKSAHSMDKFLNEIVPNTIETKKINIQNDQRKLSSMPNKTKEQQHKKRQLEDKIAKEKSHLETLESLDHEAMHKADADARKYYNQQINIEYYTSSKFIKNTGYESAKSGIKMGIRQALGIILAEVWFELKEHVPALFKDAQDNFTLELFLERIQLLAKNIWSRIKLRFKDLIEEFKNGAMAGAISSITTTILNIFFTTQKLLGRLIRETWSSLVSAAKLLFINPNKLPAGDLTREVIRILSTGVSVAMGVILNGHLANVMTFPFGTEIAAFLSAVATGLMTLGVTYFLDHSEIMQKVWSFLNQYKSEAKITLEYFQNVNKELDRFLVELTALEFNLSIAEMSHFTDSLESFSCEYEKCFVLAKEVERRGIELPFKAGDIESTRSWLKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5H2</accession>
    <name>D0Z5H2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Hypothetical conjugal transfer protein TrbF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_000079</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000006">
        <property type="protein sequence ID" value="EEZ39024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000079"/>
    <dbReference type="EnsemblBacteria" id="EEZ39024">
        <property type="protein sequence ID" value="EEZ39024"/>
        <property type="gene ID" value="VDA_000079"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3701">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1214981at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16425">
        <property type="entry name" value="TrbF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035658">
        <property type="entry name" value="TrbF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007430">
        <property type="entry name" value="VirB8"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04335">
        <property type="entry name" value="VirB8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="VirB8" evidence="6">
        <location>
            <begin position="24"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="232" mass="26135" checksum="AE41C6FBD312CCA5" modified="2010-01-19" version="1">MSANSDNNDIALERAKELSILYQKGRQEWDERMGSAISQAHSWKMACFGLILVSLSAVAGIAYIGSQSKIVPYGVALQNNQAIPIGPLAKMPPSQINALHEKQLREFVEARRSVLVDVSAQKKLIEDVYSMLMPNTPALTATSRYYKNHNVFERAQTELVTVNITSVLPISENTFQVEWEETITSRNGQVRPYIKRFKATVNTFVSIPTDTKELNRNPLGFFIRTFNIVELQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5J0</accession>
    <name>D0Z5J0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">2-methylthioadenine synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000008</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000007">
        <property type="protein sequence ID" value="EEZ39001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005307243.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000007.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000008"/>
    <dbReference type="EnsemblBacteria" id="EEZ39001">
        <property type="protein sequence ID" value="EEZ39001"/>
        <property type="gene ID" value="VDA_000008"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4249">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1712242at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041167">
        <property type="entry name" value="Saf_2TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040836">
        <property type="entry name" value="SAVED"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18303">
        <property type="entry name" value="Saf_2TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18145">
        <property type="entry name" value="SAVED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="Saf_2TM" evidence="3">
        <location>
            <begin position="8"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="SAVED" evidence="2">
        <location>
            <begin position="165"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF18303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="366" mass="41640" checksum="31EDCC59BFA4B31F" modified="2010-01-19" version="1">MTFFKDLMYRLLHWGDLLFKWYTRPKSKLFTIGKFLVVSGLSSIGLTTALKIAFITPEGYELTASFFENDTGIFILLISSCFIIVGFFLIIYDALLTIKDSGKANNILVEHIALFKPLSSSFLSTVTKAKGKMRCVKIDLSEYYRDGVLSEPSDAVNDTRVMLKKAVASLSDAIGNESTSIHYGGTPPVCLGFYSGFFIGNTTSVMLWDYDRDLEEWHCLDRSFDSNQPIIDESEYKQDLDEVCLIFSISFNIEKVARETTNTSSIITIKMPHIGHDNMSSLSKLLKFKKEFRALLNKFTQDGIKRIHIFCAAQSSFNFTMGQQITRNHPECIVYEFVNREVHPYPWGLKFNNKDCSPPIVIENKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5J1</accession>
    <name>D0Z5J1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">UBA/THIF-type NAD/FAD binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000009</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000007">
        <property type="protein sequence ID" value="EEZ39002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005307245.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000007.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000009"/>
    <dbReference type="EnsemblBacteria" id="EEZ39002">
        <property type="protein sequence ID" value="EEZ39002"/>
        <property type="gene ID" value="VDA_000009"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0476">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="881412at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008641">
        <property type="term" value="F:ubiquitin-like modifier activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="SSF69572"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ThiF" evidence="1">
        <location>
            <begin position="316"/>
            <end position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="575" mass="64958" checksum="6FC09E8BBDC15A54" modified="2010-01-19" version="1">MFDNTEVIKYLKSKEFTCQELDFKGVNIISINVEIADKRIELIHFPEPEIIALPVFLLVNPSEVGHLAHVLNYQDGDYEFGSICVNDRDAVSVNFNMPLLAIEESLNRHISILEKAITDPIWNRQELLREFKSCWLNVCDFNDRPVLLTNDSGSLEEIDVFRPVKDRKFGVNSYYLAQSKNTDLADIAKIYWKNSSDRSLAGKAVVLPLTKIKPAPLNKSQLSEWYLDIIDKQKQETINNIKENYGRWKTKEYWIIFNAQVPSGTVWFCLSFKSKKGKKHSLPLTKKQLENWKITAVPIRLFNKEAVLPRGGANLDLAITKVALVGAGSVGSEIAHKLSASGVQNLTIYDPDCYNIENLYRHVLPEEFLNYGKSLGLRFSLQRQFLWSKANSSLDKLLDLRNPRLLNTYDLIIIAIGSPTHERLFKEYLLNTGIKVPVINTWLEGFGVGGHAVLDIPESKGCLLCAYVCPDTLARGLSSNLNFIESNQNITINMSGCGEQFISYGAICSAQTALIASDLAIKYLEGKIKISSKVSWKGSEHDVKEHGITLTNRFYQFNDSLQIKPLVHEDCDVCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVK7</accession>
    <name>D0YVK7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Pyruvate-flavodoxin oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">VDA_001599</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="12">Binds 3 [4Fe-4S] clusters per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298354.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001599"/>
    <dbReference type="EnsemblBacteria" id="EEZ40572">
        <property type="protein sequence ID" value="EEZ40572"/>
        <property type="gene ID" value="VDA_001599"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0674">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1013">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1014">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1143">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10483at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016903">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022900">
        <property type="term" value="P:electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07034">
        <property type="entry name" value="TPP_PYR_PFOR_IOR-alpha_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.920.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033412">
        <property type="entry name" value="PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037112">
        <property type="entry name" value="Pyrv-flavodox_OxR_EKR_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019456">
        <property type="entry name" value="Pyrv-flavodox_OxRtase_EKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019752">
        <property type="entry name" value="Pyrv/ketoisovalerate_OxRed_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002880">
        <property type="entry name" value="Pyrv_Fd/Flavodoxin_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011895">
        <property type="entry name" value="Pyrv_flavodox_OxRed"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002869">
        <property type="entry name" value="Pyrv_flavodox_OxRed_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10371">
        <property type="entry name" value="EKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17147">
        <property type="entry name" value="PFOR_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01558">
        <property type="entry name" value="POR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01855">
        <property type="entry name" value="POR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000159">
        <property type="entry name" value="NifJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00890">
        <property type="entry name" value="EKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53323">
        <property type="entry name" value="SSF53323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02176">
        <property type="entry name" value="pyruv_ox_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 12" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5 9" id="KW-0249">Electron transport</keyword>
    <keyword evidence="7 12" id="KW-0408">Iron</keyword>
    <keyword evidence="8 12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="13">
        <location>
            <begin position="693"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="13">
        <location>
            <begin position="749"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="region of interest" description="Thiamine pyrophosphate binding" evidence="10">
        <location>
            <begin position="979"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="region of interest" description="Thiamine pyrophosphate binding" evidence="10">
        <location>
            <begin position="1008"/>
            <end position="1013"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="702"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="705"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="708"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="712"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="758"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="761"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="764"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="768"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="832"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="835"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="837"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 12">
        <location>
            <position position="860"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="1088"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="11">
        <location>
            <position position="39"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="11">
        <location>
            <position position="72"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="11">
        <location>
            <position position="122"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="11">
        <location>
            <position position="1013"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR000159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000159-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000159-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000159-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEZ40572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="1185" mass="130613" checksum="A7B7171982ED5EA9" modified="2010-01-19" version="1">MSIQIQQHTSTQYHTMDGNEAVAHVAYRCNEVIGIYPITPSSPMSEQCEVWESQGKTNLWGQVPTVIEMQSEAGAAGAVHGALMAGSLATTFTSSQGLLLKIPNMYKIAGELTPFVMHVAARTLATHALSIFGDHSDVMAVRQTGFAMLSSESVQQAHDFALISQAATLKSRIPFVHFFDGFRTSHEINKIVTIDDAIIDQMIDQQEVDAFHQRGLTPDNPTIRGTAQNPDTFFQAREASNLFYDACPNIVADTMAQFAQLTGRSYKLFDYYGHPDATDITVVMGSANATLTQAVDELLALGKKVGVISVHLYRPFSLEHFVDVLPQSVTRIAVLDRTKEPGAIGDPLYLDVVATLQQALQQQKIAQMPMIVGGRYGLSSKEFTPNHAKGIYQALAENQLIPSFTIGICDDVTHRSISYPSQAISEPKTRIRALFYGLGSDGTVSANKNTLKIIGENTELHSQGYFVYDSKKSGGVTISHLRFDHQPIEAPYLIDQAEFIACHQFEFIQKLDMVEQAAHGATVLINSPYDNEQIWDHLPQEVQQIIIERQLKLYVINAVTIARQAGLNNRLNTVMQTAFFALSQLMPVNDAIEHLKQAIEKSYSKRGPSIVAANHNAVDATLANLQQVCIPDQVTSTTTRPAIVSEHAPDLVQKVTAVMLAGKGDQLPVSAFPVDGHWPTATSQWEKRNIAHEIPVWEQDLCTQCNICTLVCPHSAIRAKAVDEAELINAPCDFKTVDYKQRDFKGKQYTLQVSPQDCTGCNLCTTACPAVDPNNSERKAINMMAKAEVLAAQTENYEFFNQLPELERIDIKRIDARSSQLLQPLFEYSGACSGCGETSYIKLLTQLFGDRMLIANATGCSSIYGGNLPTTPYTTDGHGRGPAWANSLFEDNAEFGLGMRLAVNSRRDHALYLLEQAKDMLPTDLVDALQTNAMLGDENSVVRQREHIADLRSRLDYSHQALIECADDLVAKSTWIVGGDGWAYDIGFGGLEHVLATNNNVNVLVMDTQGYSNTGGQQSKATPTGAVAKFATNGKSANSKDIAINIMMLGNVYVAKIALGANMNQALKAIQEAEAYPGPSLVIAYSPCITHGFDMSQGVTHQQLMVETGLWPLFRFDPRRCDKGRAALQLDSKAPKRDVRELIDRESRFTQIKRKNPAQYEANLEQLRQQVSHKHTLLQQLLEWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVK8</accession>
    <name>D0YVK8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Hydroxylamine reductase</fullName>
            <ecNumber evidence="7">1.7.99.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Hybrid-cluster protein</fullName>
            <shortName evidence="7">HCP</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Prismane protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">hcp</name>
        <name evidence="8" type="ORF">VDA_001600</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>A + H2O + NH4(+) = AH2 + H(+) + hydroxylamine</text>
            <dbReference type="Rhea" id="RHEA:22052"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15429"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="1.7.99.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="7">Binds 1 [2Fe-2S] cluster.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>hybrid [4Fe-2O-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:60519"/>
        </cofactor>
        <text evidence="7">Binds 1 hybrid [4Fe-2O-2S] cluster.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the HCP family.</text>
    </comment>
    <dbReference type="EC" id="1.7.99.1" evidence="7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298355.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001600"/>
    <dbReference type="EnsemblBacteria" id="EEZ40573">
        <property type="protein sequence ID" value="EEZ40573"/>
        <property type="gene ID" value="VDA_001600"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1151">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="337713at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050418">
        <property type="term" value="F:hydroxylamine reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2030">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00069">
        <property type="entry name" value="Hydroxylam_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004137">
        <property type="entry name" value="HCP/CODH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010048">
        <property type="entry name" value="Hydroxylam_reduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016099">
        <property type="entry name" value="Prismane-like_a/b-sand"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011254">
        <property type="entry name" value="Prismane-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016100">
        <property type="entry name" value="Prismane_a-bundle"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30109">
        <property type="entry name" value="PTHR30109"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30109:SF0">
        <property type="entry name" value="PTHR30109:SF0"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03063">
        <property type="entry name" value="Prismane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56821">
        <property type="entry name" value="SSF56821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01703">
        <property type="entry name" value="hybrid_clust"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="1 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7" id="KW-0408">Iron</keyword>
    <keyword evidence="6 7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="7">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="11"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="19"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="29"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>hybrid [4Fe-2O-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:60519"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>hybrid [4Fe-2O-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:60519"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="205"/>
        </location>
        <ligand>
            <name>hybrid [4Fe-2O-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:60519"/>
        </ligand>
    </feature>
    <feature type="binding site" description="via persulfide group" evidence="7">
        <location>
            <position position="293"/>
        </location>
        <ligand>
            <name>hybrid [4Fe-2O-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:60519"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="321"/>
        </location>
        <ligand>
            <name>hybrid [4Fe-2O-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:60519"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="348"/>
        </location>
        <ligand>
            <name>hybrid [4Fe-2O-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:60519"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="382"/>
        </location>
        <ligand>
            <name>hybrid [4Fe-2O-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:60519"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="384"/>
        </location>
        <ligand>
            <name>hybrid [4Fe-2O-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:60519"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="Cysteine persulfide" evidence="7">
        <location>
            <position position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ40573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="447" mass="48654" checksum="08774101F6D849E8" modified="2010-01-19" version="1">MSNLAMFCHQCSMAQTGGCGSTGKTQGTCGKDENLSRLQDIMIFGLKGLSAYRTHANDLGANTKSVDDVIAETLYFTLTNVNFSFDQHIAQLMKIGGAGSEMMSILGEAHHARLGVPTPVCVPQNQAEGKGILVTGHDLDLLERLLIATEGTGINVYTHSEMLPAHGYPELRKYSHLKGNVGKAWFDQKQLFQKWNGTIIVTTNCIVPPTGRADYADRLYSYGIVGIDGCRELADDFAPLIEHTLSLPDIDGFESTETLMTGHNYKTILGLAPQILEAVNAGKIKQFFVVAGCDKPGKPNDYFRELALSIPEDCIILTSSCGKFRFNDHDFGVVPGTEIPRYLDLGQCNDSYGAVMIALALGDAMGVPVNELPVNIVLSWMEQKAVLILLALFNLGIQNIYLGPNPPEFVNEAIFEFLQQNFNLHLTGDAKTDLATMLNGQIETAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVT9</accession>
    <name>D0YVT9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GGDEF family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_002020</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299196.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002020"/>
    <dbReference type="EnsemblBacteria" id="EEZ40988">
        <property type="protein sequence ID" value="EEZ40988"/>
        <property type="gene ID" value="VDA_002020"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3706">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013857">
        <property type="entry name" value="NADH-UbQ_OxRdtase-assoc_prot30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08547">
        <property type="entry name" value="CIA30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="3">
        <location>
            <begin position="306"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="234"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="434" mass="49773" checksum="3955DD72977AC3D8" modified="2010-01-19" version="1">MADLRQRLRYTAYWLVSITIIVYGWFYFGGAEKELVITPKNSTFRLIDDSHQGGASTAELDINPDGAILNCELVKKSQWPFCEMAISLSDSVAKGFDLSKYHAIGLDIDYDSPVEGERVRIYLRNYDESYSNETDPVSLKFNAIEYAPGKDQGLQVIPLKSFQVLSWWIAEYELPIEKAGPQFDNVSIIEIATGSYVKPTHYGITLNKLVLYGTWISEENLVKILLVIWILTALVFLTTERIRLYKQIQNAEQKAARLKTMNKVLFEKSLRFEELAYIDPLTKAKNRNAVSDWVRQVVEHSKDMAQPFSVIYIDIDFFKKINDKYGHGRGDEVLAKFADLLRRNIDKSDMLVRWGGEEFVVFCPSTSLGVVAEKAELLREAIAEYQWGNEFSVTCSLGVAQLENEEFNRLMERADEALYKAKERGRNRVEIAWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVV6</accession>
    <name>D0YVV6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002037</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299243.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002037"/>
    <dbReference type="EnsemblBacteria" id="EEZ41005">
        <property type="protein sequence ID" value="EEZ41005"/>
        <property type="gene ID" value="VDA_002037"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019755" evidence="1">
        <location>
            <begin position="23"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="210" mass="24429" checksum="163A6BFC71FF09F9" modified="2010-01-19" version="1">MRYTYIFSLLACFLLTPLETKALPTEKGMKLKTTNIGQWNLITRTDYEYDPFDDETTRTSFTVWLKPNDKSTTSFSVDFMCDKFDNMIGLYAQDSFFFSIINGATIDFKNEHDQSYSFSVERSLNKAYQKSIFVPEEDEDSLLEILKDSHKGYFRFNGQSGKNIEKVDFHNFSKSYDMYTKQCKKLALSPEIIKGRVQGICPNGCDKYFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVY5</accession>
    <name>D0YVY5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">DNA repair protein RecO</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7 8">Recombination protein O</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">recO</name>
        <name evidence="10" type="ORF">VDA_001264</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">Involved in DNA repair and RecF pathway recombination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the RecO family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297751.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001264"/>
    <dbReference type="EnsemblBacteria" id="EEZ40242">
        <property type="protein sequence ID" value="EEZ40242"/>
        <property type="gene ID" value="VDA_001264"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1381">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1758685at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00201">
        <property type="entry name" value="RecO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037278">
        <property type="entry name" value="ARFGAP/RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022572">
        <property type="entry name" value="DNA_rep/recomb_RecO_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003717">
        <property type="entry name" value="RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042242">
        <property type="entry name" value="RecO_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33991">
        <property type="entry name" value="PTHR33991"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02565">
        <property type="entry name" value="RecO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11967">
        <property type="entry name" value="RecO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57863">
        <property type="entry name" value="SSF57863"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00613">
        <property type="entry name" value="reco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5 8" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6 8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA_rep/recomb_RecO_N" evidence="9">
        <location>
            <begin position="5"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00033409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF11967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ40242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="236" mass="26834" checksum="CFE2D63F074560CA" modified="2010-01-19" version="1">MEGLQRCFVLHSRPYSETSLILDVFSEDSGRLSILSKGARRKRSNLKGALQPFTPLFMKWSGKGSMPVLTHAEPISIGLPMRSYILYSAMYVNEVLCRVLEAQTPYPVLFLDYLNVLRELAQADNPEPALRRFELALLQHLGYGIDFLHCAGSGLPVEDNMTYNYREQQGFIASIKMGQLTFTGEQLKAIDARRFETPEQLRAAKRFTRIALKPYLGSKPLKSRELFIPRGRSTRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW25</accession>
    <name>D0YW25_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SIR2_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001288</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297794.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001288"/>
    <dbReference type="EnsemblBacteria" id="EEZ40263">
        <property type="protein sequence ID" value="EEZ40263"/>
        <property type="gene ID" value="VDA_001288"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1481830at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039444">
        <property type="entry name" value="SIR2-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13289">
        <property type="entry name" value="SIR2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SIR2_2" evidence="1">
        <location>
            <begin position="215"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="399" mass="45692" checksum="0ABF31736A58509C" modified="2010-01-19" version="1">MNKPLHDSRHIIEKVEQYLDTKLQENAEFNEELNLSASVAISTEGPKINITSLSDSDTKFQFDVSDILYWVERDTYFDELAKWNGVKLEEKHNGALDFLKKSEQLPIFLDFVDAIKRQRIAPFIGAGVSLPAGYPSWGKALERLARQMGGDIPAQIKDDLDNYRYLAVAETLYLHNEHLFKNFVQTEFRLKAAQEDDRPVFPPVIDLLPLLTKSCVVTTNFDRLIEKKFELVSGKPLSGYMYGKQEQNGFVSQLLKGEQCLMKLHGDADQAQSYVFTESQYKDAYGDTDIDFTKQLPRSLRQIYISYSLIFIGCSLEQDRTLELFKSVMDQGHFEIPWHYALLADSDSASKAEKMGRLLSMNIKPIWYEVEDNNHSMLVDLLLLAIDVANKKFSLGNTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWA3</accession>
    <name>D0YWA3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">UDP-3-O-acyl-N-acetylglucosamine deacetylase</fullName>
            <shortName evidence="12">UDP-3-O-acyl-GlcNAc deacetylase</shortName>
            <ecNumber evidence="4 12">3.5.1.108</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">lpxC</name>
        <name evidence="13" type="ORF">VDA_001181</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 12">Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 12">
            <text>a UDP-3-O-[(3R)-3-hydroxyacyl]-N-acetyl-alpha-D-glucosamine + H2O = a UDP-3-O-[(3R)-3-hydroxyacyl]-alpha-D-glucosamine + acetate</text>
            <dbReference type="Rhea" id="RHEA:67816"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:137740"/>
            <dbReference type="ChEBI" id="CHEBI:173225"/>
            <dbReference type="EC" id="3.5.1.108"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 12">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 12">Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 2/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the LpxC family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.108" evidence="4 12"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001181"/>
    <dbReference type="EnsemblBacteria" id="EEZ40159">
        <property type="protein sequence ID" value="EEZ40159"/>
        <property type="gene ID" value="VDA_001181"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0774">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00359">
        <property type="reaction ID" value="UER00478"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008759">
        <property type="term" value="F:UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103117">
        <property type="term" value="F:UDP-3-O-acyl-N-acetylglucosamine deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1700.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00388">
        <property type="entry name" value="LpxC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004463">
        <property type="entry name" value="UDP-acyl_GlcNac_deAcase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011334">
        <property type="entry name" value="UDP-acyl_GlcNac_deAcase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015870">
        <property type="entry name" value="UDP-acyl_N-AcGlcN_deAcase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33694">
        <property type="entry name" value="PTHR33694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03331">
        <property type="entry name" value="LpxC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00325">
        <property type="entry name" value="lpxC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 12" id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword evidence="5 12" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="10 12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 12" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Proton donor" evidence="12">
        <location>
            <position position="255"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ40159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="295" mass="32673" checksum="DD9675A0B0CD41B9" modified="2010-01-19" version="1">MQTTGVGLHSGRKVTLILRPAAANTGVIYRRTDLNPPVDFPANADSVRDTMLCTALVNEAGVRISTVEHLNAALAGMGIDNVIIEVDAPEIPIMDGSASPFIYLLQSAGIEALNTPKRFLRIKKPVRVEDGDKWAELVPHNGFRLDFAIDFNHPAIGTDQQRLTFDFSSKSFAKDVSRARTFGFMRDIEYLQSQNLCLGGSFDNAIVLDEYRILNDDGLRFDNELVTHKVLDAIGDLYMCGHNIIGEMRAYKSGHALNNKLLRAVLADQEAYEWTTFEDEKEVPVTFAQPGMVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWE3</accession>
    <name>D0YWE3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001391</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297988.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001391"/>
    <dbReference type="EnsemblBacteria" id="EEZ40366">
        <property type="protein sequence ID" value="EEZ40366"/>
        <property type="gene ID" value="VDA_001391"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1942">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1899588at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.429.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015017">
        <property type="entry name" value="DUF1904"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014347">
        <property type="entry name" value="Tautomerase/MIF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08921">
        <property type="entry name" value="DUF1904"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55331">
        <property type="entry name" value="SSF55331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="111" mass="12599" checksum="6E81737F385F1C8E" modified="2010-01-19" version="1">MPHLRFRAIDFDTVKALSTELVDELQPLMDCPREDFTLEHIPASFIFDGDVSEAYPFVEVFWFHRGQETQDSVAKAITAAVRKAMDAPEQDVAVIFTALTPAAYYDNGEHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWH2</accession>
    <name>D0YWH2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001431</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298050.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001431"/>
    <dbReference type="EnsemblBacteria" id="EEZ40405">
        <property type="protein sequence ID" value="EEZ40405"/>
        <property type="gene ID" value="VDA_001431"/>
    </dbReference>
    <dbReference type="GeneID" id="57339644"/>
    <dbReference type="eggNOG" id="COG2888">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1667059at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009912">
        <property type="entry name" value="DUF1451"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07295">
        <property type="entry name" value="DUF1451"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="160" mass="18038" checksum="A739236A6834FE0F" modified="2010-01-19" version="1">MPKQKAEYELLLEKATEALKHSPEKLKEFLEVTEKYGEAASDMTKDELALIKAYLKSDMKEFADNVEKSSEPFAESPFYKLVSESIWQGLADITDKTQVEWHEVTADLEHHGVYKAGELIGLGELVCQKCGHKQVITHVTRIEPCIKCGGVEFTRKPLAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWI8</accession>
    <name>D0YWI8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Pyridoxal phosphate homeostasis protein</fullName>
            <shortName evidence="1">PLP homeostasis protein</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001230</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297686.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001230"/>
    <dbReference type="EnsemblBacteria" id="EEZ40208">
        <property type="protein sequence ID" value="EEZ40208"/>
        <property type="gene ID" value="VDA_001230"/>
    </dbReference>
    <dbReference type="GeneID" id="57339892"/>
    <dbReference type="eggNOG" id="COG0325">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1423012at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02087">
        <property type="entry name" value="PLP_homeostasis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001608">
        <property type="entry name" value="Ala_racemase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011078">
        <property type="entry name" value="PyrdxlP_homeostasis"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10146">
        <property type="entry name" value="PTHR10146"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01168">
        <property type="entry name" value="Ala_racemase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004848">
        <property type="entry name" value="YBL036c_PLPDEIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="SSF51419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00044">
        <property type="entry name" value="TIGR00044"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01211">
        <property type="entry name" value="UPF0001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ala_racemase_N" evidence="4">
        <location>
            <begin position="22"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="1 2">
        <location>
            <position position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR004848-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="233" mass="25434" checksum="51E9EB7078A62396" modified="2010-01-19" version="1">MTSIKQNIEQVISEIDAAAKKCGRTADSVQLLAVSKTKPIAAIEEAIQAGQFAFGENYVQEGVEKIEHFRAHPQADALTWHFIGPLQSNKSRPVAENFDWVHSVDRLKIAQRLNDQRPTDLPPLNVLLQINTSGEASKSGLDFEQVAELANQVAQMPNLVLRGLMSIPEQADDYESQLAAFRSLAQALEQLKPLHPQLDTLSMGMSGDMDAAIAAGSTIVRIGTAIFGARNYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWK2</accession>
    <name>D0YWK2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8 9">Chorismate synthase</fullName>
            <shortName evidence="8">CS</shortName>
            <ecNumber evidence="4 8 9">4.2.3.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">5-enolpyruvylshikimate-3-phosphate phospholyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">aroC</name>
        <name evidence="11" type="ORF">VDA_001493</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8 9">
            <text>5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21020"/>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57701"/>
            <dbReference type="EC" id="4.2.3.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8 9">
            <name>FMNH2</name>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
        </cofactor>
        <text evidence="8 9">Reduced FMN (FMNH(2)).</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8 9">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8 9">Belongs to the chorismate synthase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.5" evidence="4 8 9"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298155.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001493"/>
    <dbReference type="EnsemblBacteria" id="EEZ40467">
        <property type="protein sequence ID" value="EEZ40467"/>
        <property type="gene ID" value="VDA_001493"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0082">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="981870at2"/>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004107">
        <property type="term" value="F:chorismate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd07304">
        <property type="entry name" value="Chorismate_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00300">
        <property type="entry name" value="Chorismate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000453">
        <property type="entry name" value="Chorismate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035904">
        <property type="entry name" value="Chorismate_synth_AroC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020541">
        <property type="entry name" value="Chorismate_synthase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21085">
        <property type="entry name" value="PTHR21085"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01264">
        <property type="entry name" value="Chorismate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001456">
        <property type="entry name" value="Chorismate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103263">
        <property type="entry name" value="SSF103263"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00033">
        <property type="entry name" value="aroC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00787">
        <property type="entry name" value="CHORISMATE_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00788">
        <property type="entry name" value="CHORISMATE_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00789">
        <property type="entry name" value="CHORISMATE_SYNTHASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 8 9" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0274">FAD</keyword>
    <keyword evidence="8" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0288">FMN</keyword>
    <keyword evidence="7 8 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0521">NADP</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="125"/>
            <end position="127"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="238"/>
            <end position="239"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="278"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="293"/>
            <end position="297"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="319"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ40467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="362" mass="39355" checksum="86EB3DDC2E6639CB" modified="2010-01-19" version="1">MAGNTIGQVFRVTTFGESHGVALGCIIDGCPPGLELTESDMQHDLDRRRPGTSKYTTQRREADEVKILSGVFEGKTTGTSIGLLIENTDQRSKDYSNIQDLFRPGHADYTYHQKYGIRDYRGGGRSSARETAMRVAAGAVAKKYLKQVHGVEVRAYLSQMGDVSIDKVDWQQIEQNAFFCPDVDKVDAFDELIRQLKKEGDSIGAKLTVVAKNVPVGLGEPVFDRLDADIAHSLMSINAVKGVEIGDGFDVVEQRGSEHRDEMTPQGFKTNHAGGILGGISSGQDIVAHIALKPTSSITVPGETITKQGESAEVVTKGRHDPCVGIRAVPIAEAMLAITLMDHLLRHRAQNFGVVTETPKIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-06-02" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWL3</accession>
    <name>D0YWL3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001504</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001504"/>
    <dbReference type="EnsemblBacteria" id="EEZ40478">
        <property type="protein sequence ID" value="EEZ40478"/>
        <property type="gene ID" value="VDA_001504"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4775">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="516968at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010344">
        <property type="entry name" value="YbjH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06082">
        <property type="entry name" value="YjbH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018633" evidence="2">
        <location>
            <begin position="35"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="303"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="737" mass="83336" checksum="3A0D1B23D1040BBC" modified="2010-01-19" version="1">MTLSSRLTAGSMMRPAFALSTITVALLSSFTAQADNFSYPELKHSQSDFGGVGLLQMPTSRMNPEGEFTFGTTYNDDYHHYWVSLQLFPWLETTIRYTQVQDMLYSGDEGFSGNTKYTDKGIDFKLRLLNESYWLPEVSVGVRDFGGTGLFDGEFIAANKQFGPLDFTLGMGWSYIGQRGNITNPFCKVSDSFCQRLSDYKGNGGSFDTGRWFKGPASIYGGVEYQTPLAPLRLKLEYDGNDYSQDFPVTRGGKSMTQATPWNFGAHYQLTDWADAKLSYERGNTLTLGLSLNTNFNDLKDSWLDEPEPKANTSQNPKQLTKEEWNTLAQQIESVSGYQDPAIYQSDSVITVVAEQKKYRNRDEAHQRITTLLANSAPTVDEYRIIETKNRQPVIENIYEHDDVVTVANNLDIHKDIANITQVATPGKVVGKSVADSQENWDFGLSPVLQQSFGASEGFYLFNIGVNASANYWFNDNLQLGGSVYVNIYDTYDKFKYETPPDGTDNIRVRTLIRQYVNDNPVYANNLQLTWMDKFANNWYAQAYGGYLEMMYGGVGGEVLYRPMNSNWAFGADLNYVKQRDPNSQFGFYTKEVQYDEHLGRNYRVQTGTAVGNITAYYQPQWQWLENTLFKVSAGRYLAEDVGVTIDFSKQFDSGIIAGAFATITDMSTEEYGEGSYTKGFYISIPFDLMTVRPSTERASISWMPLTRDGGQMLNRKYSLYGLTDARSPWYERAPLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWN4</accession>
    <name>D0YWN4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">Mannose-6-phosphate isomerase</fullName>
            <ecNumber evidence="3 6">5.3.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_001490</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-mannose 6-phosphate = D-fructose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:12356"/>
            <dbReference type="ChEBI" id="CHEBI:58735"/>
            <dbReference type="ChEBI" id="CHEBI:61527"/>
            <dbReference type="EC" id="5.3.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5 6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5 6">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the mannose-6-phosphate isomerase type 1 family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.8" evidence="3 6"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001490"/>
    <dbReference type="EnsemblBacteria" id="EEZ40464">
        <property type="protein sequence ID" value="EEZ40464"/>
        <property type="gene ID" value="VDA_001490"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1482">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004476">
        <property type="term" value="F:mannose-6-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009298">
        <property type="term" value="P:GDP-mannose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001250">
        <property type="entry name" value="Man6P_Isoase-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016305">
        <property type="entry name" value="Mannose-6-P_Isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018050">
        <property type="entry name" value="Pmannose_isomerase-type1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10309">
        <property type="entry name" value="PTHR10309"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01238">
        <property type="entry name" value="PMI_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001480">
        <property type="entry name" value="Mannose-6-phosphate_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00714">
        <property type="entry name" value="MAN6PISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00218">
        <property type="entry name" value="manA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00965">
        <property type="entry name" value="PMI_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00966">
        <property type="entry name" value="PMI_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0862">Zinc</keyword>
    <feature type="active site" evidence="4">
        <location>
            <position position="261"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="242"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR001480-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001480-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ40464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="376" mass="41263" checksum="15ECCC7A3E1CB410" modified="2010-01-19" version="1">MTSVNQLFGIENPENKPQAEIWMGAHANGCSQIEVNGQDTRLSDFIATNPDAILGATTQAQFGELPYLFKVLAAEKALSIQVHPNKAQAEIGFAKEEEMGIARNAANRNYKDPNHKPELVFALTPYQAMNGFREITDIVTNFKQLDIAELKSLVSQFETNQTEAGLAQFFTEMLSLDGEQKEQAVEALIAYSKQHQDDEFFALLVDLSEQYPGDIGLFAPLMLNVLTLNPGEAMFLDACTPHAYIKGTGLEIMANSDNVLRAGLTPKYMDVPELVANTIFRTMPFDSLLLAANEAEGGLHYPIPVPDFKFSVYKQATGTDILVNSAEILFAVDAPLTVTHVNGQTMTINKGESLFVPAYAQTYQASCDGVFARAYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWP8</accession>
    <name>D0YWP8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 12">Outer-membrane lipoprotein LolB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">lolB</name>
        <name evidence="13" type="ORF">VDA_001444</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 12">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell outer membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the LolB family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298073.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001444"/>
    <dbReference type="EnsemblBacteria" id="EEZ40418">
        <property type="protein sequence ID" value="EEZ40418"/>
        <property type="gene ID" value="VDA_001444"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3017">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1797257at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044874">
        <property type="term" value="P:lipoprotein localization to outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16326">
        <property type="entry name" value="LolB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00233">
        <property type="entry name" value="LolB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029046">
        <property type="entry name" value="LolA/LolB/LppX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004565">
        <property type="entry name" value="OM_lipoprot_LolB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03550">
        <property type="entry name" value="LolB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89392">
        <property type="entry name" value="SSF89392"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00548">
        <property type="entry name" value="lolB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="12" id="KW-0143">Chaperone</keyword>
    <keyword evidence="11 13" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0564">Palmitate</keyword>
    <keyword evidence="8 12" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="6 12" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ40418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="217" mass="24619" checksum="187D00A637ED36FF" modified="2010-01-19" version="1">MHSTIDLKLKSSIKSIGCSFNWRVISLGFLVTLMTGCASQSPEISQKVNWPTQEQQLSKLTHYQASGKLAYKDNQQRFGANLNWQTNNQNDHLLLTNFLGQTLIKLDTTPKSVTLIDYKGNEYHGTNAAELVRRLTGINLPIEQMQNWLIGLPTAADTFQLNDQGVVGYLAKQIGPQLWEMHYQEYDFSQHPALPSKMILSQGKQKITLVINEWNLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWV4</accession>
    <name>D0YWV4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">UTP--glucose-1-phosphate uridylyltransferase</fullName>
            <ecNumber evidence="3 5">2.7.7.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">UDP-glucose pyrophosphorylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_001546</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>alpha-D-glucose 1-phosphate + H(+) + UTP = diphosphate + UDP-alpha-D-glucose</text>
            <dbReference type="Rhea" id="RHEA:19889"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="2.7.7.9"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the UDPGP type 2 family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.9" evidence="3 5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298251.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001546"/>
    <dbReference type="EnsemblBacteria" id="EEZ40520">
        <property type="protein sequence ID" value="EEZ40520"/>
        <property type="gene ID" value="VDA_001546"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1210">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1402673at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003983">
        <property type="term" value="F:UTP:glucose-1-phosphate uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006011">
        <property type="term" value="P:UDP-glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02541">
        <property type="entry name" value="UGPase_prokaryotic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005771">
        <property type="entry name" value="GalU_uridylyltTrfase_bac/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43197">
        <property type="entry name" value="PTHR43197"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01099">
        <property type="entry name" value="galU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transferase" evidence="6">
        <location>
            <begin position="7"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="300" mass="32382" checksum="F90822255DD7B74A" modified="2010-01-19" version="1">MNNSVRKAVIPVAGLGTRMLPATKAIPKEMLPIVDKPLIQYVVNECVAAGIKEIVLVTHSSKNSIENHFDTSFELEATLEQRVKRQLLAEVQAICPPDVTIMHVRQGQAKGLGHAILCAQPLVGDAPFAVVLPDVILDDAASNLETDNLAKMVQRFNETKVSQVMVEPVPMNDVSSYGVADIGGVELGAGESSPMTKVVEKPPVEEAPSNLAIVGRYVLPAEIWSLLEKTPVGAGGEIQLTDAIDMLMKQQEVDAFHMSGKSHDCGNKLGYMAAFVEYGLRHSDLGEDFKAYLQDVVKGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX18</accession>
    <name>D0YX18_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Porin_4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_001896</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell outer membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Gram-negative porin family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298891.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001896"/>
    <dbReference type="EnsemblBacteria" id="EEZ40864">
        <property type="protein sequence ID" value="EEZ40864"/>
        <property type="gene ID" value="VDA_001896"/>
    </dbReference>
    <dbReference type="GeneID" id="57341981"/>
    <dbReference type="eggNOG" id="COG3203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1064531at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015288">
        <property type="term" value="F:porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034220">
        <property type="term" value="P:ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00342">
        <property type="entry name" value="gram_neg_porins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033900">
        <property type="entry name" value="Gram_neg_porin_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001897">
        <property type="entry name" value="Porin_gammaproteobac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13609">
        <property type="entry name" value="Porin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00183">
        <property type="entry name" value="ECOLIPORIN"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019857" description="Porin_4 domain-containing protein" evidence="4">
        <location>
            <begin position="22"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="domain" description="Porin_4" evidence="5">
        <location>
            <begin position="13"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="341" mass="37082" checksum="08465294964BC3CE" modified="2010-01-19" version="1">MMKKILALSISAACIATSAQAATVYQDGDSKVTIGGRLAVKAQYTESTKDTSSTTELENASSRINFGFEHRMTQNWLAGAKAEWGYDALSSGKQEFSNRLGNLYFANQDAGLITVGKQWSTYYDITGWTDVFWIYGGEASGTYDGRDGHGGSGTGRADDAISYRNSFNGLNVAAQYQFEDGSSEGERRYGLQGALSYDLGLGLSFGGAYNLTKYHQESDDKTWTLGAKYDSDMFYLAGQYGQYRNHTNINGNLTDVAKKAYGYELVAAYLAEGGLYQVYGGYNHLADDNSSARYSYGLVGAAWTPGNMVFSAEYKLGVTNKDQNGANNGADQVALLARYNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX21</accession>
    <name>D0YX21_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 9">Integration host factor subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_001886</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Heterodimer of an alpha and a beta chain.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the bacterial histone-like protein family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001886"/>
    <dbReference type="EnsemblBacteria" id="EEZ40854">
        <property type="protein sequence ID" value="EEZ40854"/>
        <property type="gene ID" value="VDA_001886"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0776">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13835">
        <property type="entry name" value="IHF_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000119">
        <property type="entry name" value="Hist_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020816">
        <property type="entry name" value="Histone-like_DNA-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010992">
        <property type="entry name" value="IHF-like_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005684">
        <property type="entry name" value="IHF_alpha"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33175">
        <property type="entry name" value="PTHR33175"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00216">
        <property type="entry name" value="Bac_DNA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01727">
        <property type="entry name" value="DNABINDINGHU"/>
    </dbReference>
    <dbReference type="SMART" id="SM00411">
        <property type="entry name" value="BHL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47729">
        <property type="entry name" value="SSF47729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00987">
        <property type="entry name" value="himA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00045">
        <property type="entry name" value="HISTONE_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="5 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 9" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3 9" id="KW-0810">Translation regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ40854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="72" mass="8329" checksum="88952CA5D644DCF0" modified="2010-01-19" version="1">MEVFFEEVRKALENGEQVKLSGFGNFDLRDKNERPGRNPKTGEDIPITARRVVTFRPGQKLKARVEKLEVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXF1</accession>
    <name>D0YXF1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001630</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298406.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40603">
        <property type="protein sequence ID" value="EEZ40603"/>
        <property type="gene ID" value="VDA_001630"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5033GHE">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1984147at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="178" mass="21196" checksum="B7BE8ED650EF5310" modified="2010-01-19" version="1">MIRSDRLLYEIGPDGFGERHCESLDHWKLRAHMTLPNFPDDVLEQWLYRHWKGVMYNWGWLDFRGMVFTKETWSTEDILAKVQTPSQDVIDRLSQRMTNVMFQRSWLVQNMTERGTWPVAPIVLDFERDLYASNGKILKAPFNLLEGHHRLAYLKGLVEQGEYVRDQHELWIAKIPVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXJ7</accession>
    <name>D0YXJ7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001711</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001711"/>
    <dbReference type="EnsemblBacteria" id="EEZ40682">
        <property type="protein sequence ID" value="EEZ40682"/>
        <property type="gene ID" value="VDA_001711"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2931">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018511">
        <property type="entry name" value="Hemolysin-typ_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001343">
        <property type="entry name" value="Hemolysn_Ca-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019959">
        <property type="entry name" value="T1SS-143_rpt-cont_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019960">
        <property type="entry name" value="T1SS_VCA0849"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00353">
        <property type="entry name" value="HemolysinCabind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51120">
        <property type="entry name" value="SSF51120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03660">
        <property type="entry name" value="T1SS_rpt_143"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03661">
        <property type="entry name" value="T1SS_VCA0849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00330">
        <property type="entry name" value="HEMOLYSIN_CALCIUM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2491"/>
            <end position="2512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="2498"/>
            <end position="2512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="4816" mass="510139" checksum="83EB63B5F9448049" modified="2010-01-19" version="1">[encoded data, 4816 characters]</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXP2</accession>
    <name>D0YXP2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Long-chain-fatty-acid--CoA ligase</fullName>
            <ecNumber evidence="3">6.2.1.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001745</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="6.2.1.3" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001745"/>
    <dbReference type="EnsemblBacteria" id="EEZ40713">
        <property type="protein sequence ID" value="EEZ40713"/>
        <property type="gene ID" value="VDA_001745"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0318">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004467">
        <property type="term" value="F:long-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="2"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="2">
        <location>
            <begin position="143"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="225" mass="25305" checksum="28C2CDD33FFEEB77" modified="2010-01-19" version="1">MKVAISGGASMPVEIIRRFEEKLNVPVIEGYGLSESSPVAAFNLLEYERKPGSIGQPLPGVTMKAVDKDGNEVAQGQEGELLIRGHNVMKGYYKKPEETAKTVVDGWLHTGDIVRFDEDGYVYVVDRLKEVIIRGGYNIYPRDIEETFMTHPAVHQIAVIGIPHKSFGEEAKAFIMLKEDAQISEKELINWGKERLADYKYPRHIELVTSYPMTATGKILKRLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXR7</accession>
    <name>D0YXR7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299371.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002080"/>
    <dbReference type="EnsemblBacteria" id="EEZ41048">
        <property type="protein sequence ID" value="EEZ41048"/>
        <property type="gene ID" value="VDA_002080"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031C2D">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1141294at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018666" evidence="1">
        <location>
            <begin position="20"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="220" mass="25228" checksum="EF18ABD11FEB807B" modified="2010-01-19" version="1">MKKILIIIVMMITSSLSLANNKHDITEFDYPFLLGDWYWFSPSDDGVESDGVHYRAMNIKFKSTYQFMLRMLKADGSVDEWVGTYDIDESSVTLFANGHPEQSHSYMLSYNQFILDGARFTKLAPENLPGNWRSSQLSGKDIHQEIEELSLSLRPDFLFSAEVSDKEGKTKQHQGVYYLEDNNIVLMYETGQHSSEFQLASDTLTLTNTDFGMEAVMLRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXT5</accession>
    <name>D0YXT5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome c oxidase subunit CcoO</fullName>
            <ecNumber evidence="7">1.9.3.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_002098</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.9.3.1" evidence="7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299428.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002098"/>
    <dbReference type="EnsemblBacteria" id="EEZ41066">
        <property type="protein sequence ID" value="EEZ41066"/>
        <property type="gene ID" value="VDA_002098"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2993">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1469969at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003468">
        <property type="entry name" value="Cyt_c_oxidase_monohaem-su/FixO"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02433">
        <property type="entry name" value="FixO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00781">
        <property type="entry name" value="ccoO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="6">
        <location>
            <begin position="53"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="203" mass="23021" checksum="580B529558CEE252" modified="2010-01-19" version="1">MAKNRHEIVEKNVGLLAILIIVGISFGALVEITPLMYQKQTTEPVQDLQPYTALQMEGRDVYIREGCNVCHSQMIRPFRSETERYGHYSVAGESVWEHPFLWGSKRTGPDLARVGGRYSDEWHYVHLMDPRAVVPESNMPAFPWLAENQLDGQLTAKKLTIFKDQFGVPYTDQDIQNAPEAVKGKTEMDALIAYLQSLGHAMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXX9</accession>
    <name>D0YXX9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002142</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299530.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002142"/>
    <dbReference type="EnsemblBacteria" id="EEZ41110">
        <property type="protein sequence ID" value="EEZ41110"/>
        <property type="gene ID" value="VDA_002142"/>
    </dbReference>
    <dbReference type="GeneID" id="57341722"/>
    <dbReference type="eggNOG" id="ENOG5032T5D">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1542147at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008769">
        <property type="entry name" value="PhaF_PhaI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05597">
        <property type="entry name" value="Phasin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="212" mass="23208" checksum="4B7CE37CFF47E520" modified="2010-01-19" version="1">MAIFTKSTPDKKDKAGVRDTMVHNIWLAGLGAYAKSSEEVNQLSDKGKTLFDELIERGKAVESHTKERVHTAKSQTSVVLEERVHKVVQKLIGLDNDRLDQVDDKIDQLTASIEALVAKKEKEVAPKRAGRKAKAEASAKPATRGRKAGIARRKTEKTEVVAAKPVPKVEPVTEKAAELAKKVEVVATNTVTEVKNAVTQTEQNKPQEPVKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY08</accession>
    <name>D0YY08_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CopG protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002171</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299584.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002171"/>
    <dbReference type="EnsemblBacteria" id="EEZ41139">
        <property type="protein sequence ID" value="EEZ41139"/>
        <property type="gene ID" value="VDA_002171"/>
    </dbReference>
    <dbReference type="GeneID" id="57341688"/>
    <dbReference type="eggNOG" id="COG3019">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1676023at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007332">
        <property type="entry name" value="DUF411"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04214">
        <property type="entry name" value="DUF411"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019834" evidence="1">
        <location>
            <begin position="21"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="148" mass="16597" checksum="271ECE7DF2E60798" modified="2010-01-19" version="1">MKIKTLLMASLLALSTQTMAETIKGTNYQSPYCGCCKEWVKHMKDNGFDLDIVYEENLTPVKIKLGLQPQLASCHTAEIEGYTFEGHIPASDIKRFLDKKPKRMIGLAVPGMPMGSPGMEYGDKKDAYDVVAFDKNGKTMVWSRQNQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY63</accession>
    <name>D0YY63_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">HTH-type transcriptional repressor PurR</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Pur regulon repressor</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Purine nucleotide synthesis repressor</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">purR</name>
        <name evidence="9" type="ORF">VDA_002226</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Purine metabolism; purine nucleotide biosynthesis [regulation].</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="domain">
        <text evidence="7">Consists of two structural and functional domains: an N-terminal DNA-binding domain, approximately the first 60 residues, and a larger C-terminal domain, approximately 280 residues, which imparts the function of corepressor binding and oligomerization.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299689.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002226"/>
    <dbReference type="EnsemblBacteria" id="EEZ41194">
        <property type="protein sequence ID" value="EEZ41194"/>
        <property type="gene ID" value="VDA_002226"/>
    </dbReference>
    <dbReference type="GeneID" id="57341621"/>
    <dbReference type="eggNOG" id="COG1609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1796334at2"/>
    <dbReference type="UniPathway" id="UPA00488"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006164">
        <property type="term" value="P:purine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01277">
        <property type="entry name" value="HTH_type_PurR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023588">
        <property type="entry name" value="Tscrpt_reg_HTH_PurR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00036">
        <property type="entry name" value="HTHLACI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 7" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0678">Repressor</keyword>
    <keyword evidence="6 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 7" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="8">
        <location>
            <begin position="2"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="7">
        <location>
            <begin position="4"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="DNA-binding region" evidence="7">
        <location>
            <begin position="48"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>hypoxanthine</name>
            <dbReference type="ChEBI" id="CHEBI:17368"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>hypoxanthine</name>
            <dbReference type="ChEBI" id="CHEBI:17368"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>hypoxanthine</name>
            <dbReference type="ChEBI" id="CHEBI:17368"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>hypoxanthine</name>
            <dbReference type="ChEBI" id="CHEBI:17368"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="274"/>
        </location>
        <ligand>
            <name>hypoxanthine</name>
            <dbReference type="ChEBI" id="CHEBI:17368"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="334" mass="37576" checksum="B44E7EE237B668E2" modified="2010-01-19" version="1">MATIKDVARMAGVSTTTVSHVINKTRFVAEATQKKVMAAVDELNYAPSAVARSLKCNTTRTIGMLVTKSTNPFFAEVVHGVEEYCYKEGYTLILCNTEGNLSKQQDYLRMLAEKRVDGLLVMCSDLDEKLLELLERKKDLPMVIMDWGPESPHTDKIQDNAEHGGYIATKHFIENGHTKIGCLSGHEDKSTCRERLKGFRKAMAESNLSVNEDWILEGDFECDTAVKAAQDFIAMTERPTAIFCFNDIMAMAMISTFEQAGLRVPDDISIIGYDNIDLAPYFSPPLTTIHQPKRRLGKTAVEILMDRVKDKNHERQTFEMAPELVIRKSVKKIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY73</accession>
    <name>D0YY73_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Arginine ABC transporter ATP-binding protein ArtP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_002236</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ABC transporter superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002236"/>
    <dbReference type="EnsemblBacteria" id="EEZ41204">
        <property type="protein sequence ID" value="EEZ41204"/>
        <property type="gene ID" value="VDA_002236"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1126">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015424">
        <property type="term" value="F:ABC-type amino acid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030679">
        <property type="entry name" value="ABC_ATPase_HisP-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039085">
        <property type="entry name" value="ABC_ATPase_HisP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="8"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="40"/>
            <end position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ41204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="247" mass="27251" checksum="7FAE3B95415C4448" modified="2010-01-19" version="1">MQIFNMGIQVSNVNKSYGTTQVLHDINFECDQGDTLVLLGPSGAGKSSLLRVLNLLEDANSGQLNIANGRYDFDAGICEKEGLALRRKVGMVFQQYNLWPHMTVLENLIEAPMKVAGLNKDQAIKEAKDILRTLHLEDKADAWPLHLSGGQQQRVAIARALMMKPEVLLFDEPTAALDPEITAQVVNIIKQLSATGITQIIVTHEVDFAKKVASHILYLEQGKVVEHGDSSSFTSPKTQAFSDYLKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY90</accession>
    <name>D0YY90_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002253</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41221">
        <property type="protein sequence ID" value="EEZ41221"/>
        <property type="gene ID" value="VDA_002253"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="95" mass="10793" checksum="B2F7C362190EF1AD" modified="2010-01-19" version="1">MGKLFPRNITDKIATLWVITCTPTCEITDNTSRVIGSHHFSAIFIINRTVRNVNPFCLIESIWAAALNHWRANNRDRLGCRNGYRTLVINGFCGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYE6</accession>
    <name>D0YYE6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Hydroxyethylthiazole kinase</fullName>
            <ecNumber evidence="9">2.7.1.50</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">4-methyl-5-beta-hydroxyethylthiazole kinase</fullName>
            <shortName evidence="9">TH kinase</shortName>
            <shortName evidence="9">Thz kinase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">thiM</name>
        <name evidence="10" type="ORF">VDA_002309</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>5-(2-hydroxyethyl)-4-methylthiazole + ATP = 4-methyl-5-(2-phosphooxyethyl)-thiazole + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24212"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17957"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58296"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.50"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 9">Cofactor biosynthesis; thiamine diphosphate biosynthesis; 4-methyl-5-(2-phosphoethyl)-thiazole from 5-(2-hydroxyethyl)-4-methylthiazole: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the Thz kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.50" evidence="9"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299835.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002309"/>
    <dbReference type="EnsemblBacteria" id="EEZ41277">
        <property type="protein sequence ID" value="EEZ41277"/>
        <property type="gene ID" value="VDA_002309"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2145">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1717689at2"/>
    <dbReference type="UniPathway" id="UPA00060">
        <property type="reaction ID" value="UER00139"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004417">
        <property type="term" value="F:hydroxyethylthiazole kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01170">
        <property type="entry name" value="THZ_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00228">
        <property type="entry name" value="Thz_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000417">
        <property type="entry name" value="Hyethyz_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02110">
        <property type="entry name" value="HK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000513">
        <property type="entry name" value="Thz_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01099">
        <property type="entry name" value="HYETHTZKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00694">
        <property type="entry name" value="thiM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="7 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="9 10" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="9">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ41277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="268" mass="28298" checksum="DEC60D63A53BCE0B" modified="2010-01-19" version="1">MEQHDYHSLIIQSLATLKQQKPLVVNLTNYVVMNNTANALLAIGASPIMAHSRDELAELMTISGALVINIGTLDSHWIPRMHFAIEQANRYNKPVVIDPVGCGASQLRTQTAQDLVALANNVTIRGNASEIIALAGHMSNSKGVDAQDSTTQACSAAKQLAQQYQCCVVISGEIDYIVDAGTTVTITNGHAMMPHVTGMGCTHTALTGAFAAIGETTGVTATALLGIAGEIAAENSAGPGSLQVNLLDTLYQLDSEIIEHRLRLSVIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYE8</accession>
    <name>D0YYE8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GGDEF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002311</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002311"/>
    <dbReference type="EnsemblBacteria" id="EEZ41279">
        <property type="protein sequence ID" value="EEZ41279"/>
        <property type="gene ID" value="VDA_002311"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3706">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="275"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="2">
        <location>
            <begin position="321"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="446" mass="52338" checksum="5BB3BCFCB114B0C9" modified="2010-01-19" version="1">MLLLLPDSRRMNQDYQHSLTQCKLFTFFKICIVSLFLFSICYQGYNIYRIENLQQTIISTYQELFSISRRFSSYYNNAEAKKMNSGTYEKHGVSIIVNQESEVKSLSKGIKKLKFELNRVAPNSIWTIAVLENPALYGHFDPLRQEYREDYATYTKNSLMNRIVRIEGIEDTYKHFYGCNIKMTDSYLEQGTNKTVRTIYYPIYNDKKLESILAIDIKSNLISKIIDRYNKNELTVINNNNKIHNIYNVKFLIPCASNQPIIIGINYIDILKRSSMLALVFSTIVFIFYLSIENKTHFLQRDKMTGFYRRDFYENKLNKLDNFSMLIIDIDNFKQINDTYGHKKGDDIIHYVAKRILDNIRQKDIAIRWGGEEFIIIFNSMDCSSLYSRAEYIRNLISREPICGLDITISIGGLCEQDTTFTESYRRADAALYESKHNGRNRVTII</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYF0</accession>
    <name>D0YYF0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nucleoside permease NupC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002313</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41281">
        <property type="protein sequence ID" value="EEZ41281"/>
        <property type="gene ID" value="VDA_002313"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1972">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005337">
        <property type="term" value="F:nucleoside transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008276">
        <property type="entry name" value="C_nuclsd_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011657">
        <property type="entry name" value="CNT_C_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10590">
        <property type="entry name" value="PTHR10590"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07662">
        <property type="entry name" value="Nucleos_tra2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="182"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="227"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="273"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleos_tra2_C" evidence="2">
        <location>
            <begin position="86"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="293" mass="32084" checksum="A47731C061454D40" modified="2010-01-19" version="1">MQHTKILPVVIRFIGFILSKINGMGKLESFNAISALMVGQSENFITYKDILGKMSERRMYTLAATAMSTVSMSIVGSYMKLIEPKYVVAALILNMFSTFIILSVINPYDHEAEIDFDDMMVVDEEEEKKLTFFEMLGEYILTGFKVAVIVAAMLIGFIAIITMINQLCSHAFGISFQDMIGYLFYPVAWILGIPAHEALQAGSIMATKLVSNEFVAMMSLQKVASQLSAHTIGTISIFLVSFANFSSIGIIAGAVKGVNEEKGNMVARFGLRLLYGSTLVSILSAMIASLVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYH3</accession>
    <name>D0YYH3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Multidrug resistance protein NorM</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Na(+)/drug antiporter</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_002336</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299905.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002336"/>
    <dbReference type="EnsemblBacteria" id="EEZ41304">
        <property type="protein sequence ID" value="EEZ41304"/>
        <property type="gene ID" value="VDA_002336"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0534">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1415498at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006603">
        <property type="entry name" value="DinF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="92"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="128"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="153"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="187"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="234"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="282"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="312"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="356"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="392"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="418"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00030855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="456" mass="49659" checksum="30384EE25DA51E6E" modified="2010-01-19" version="1">MHNYRRETGQLLKLAIPVLFASVAQTSMGFVDTVMAGGVSATDMAAVSVAASIWLPSILFGVGLLMALVPIVAQLNGSGRRHKIPFEVQHGIVLALLVTIPIMLILYNSGLLIQYMHVEEHLAAKTVGYLHAVVFAVPAFLLFQALKSFSDGLSLTVPGMVIGFIGLFANIPLNWIFVYGKFGMPELGGVGCGVATAIVYWLMFFAMLAYVLLHPRLKKIDVFATWYKPQVKELVRLFKMGFPIAASMFFEVSLFAVIALLISPLGSIVVASHQVALNFSSLVYMLPMSLGAALSIRVGFMLGQKDIDGAKIACHCGFATALLMAMTTAVLTVIFREDITRLYSHNPDVLILAGKLLLLAAIYQCTDAIQVVAAGALRGYKDMRAIFTRTFIAYWVLGLPIGYILGMTDWIVPAMGPQGFWIGFIIGLTAAAIMLGKRVLWVQSLSREQQLEMSNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYI9</accession>
    <name>D0YYI9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_002352</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the UPF0718 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299935.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41320">
        <property type="protein sequence ID" value="EEZ41320"/>
        <property type="gene ID" value="VDA_002352"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0701">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1559099at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005524">
        <property type="entry name" value="DUF318"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03773">
        <property type="entry name" value="ArsP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="57"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="238"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="268"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="306"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="334"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="357" mass="38519" checksum="58F38A41B00351FF" modified="2010-01-19" version="1">MNTELISMAKEAADMFVFLAAELTILFIAISYLVGVLQEFLTPEKIQSILSSRKGKGYFVAALLGAITPFCSCSTIPFLKGLLRARAGFGPMMVFLFSSPLLNPVIIGLFVVTFGWKVAVFYFAIALIVSVVAGYLLEKLGFERYVKPEAYQDSSASSCSTGCGETKPSQTSCCTESTASKHVEPTSSCCSTKPATNTQKKENETSCCSSQPVEKTLQKPQSRWVRIWHSTWKDFKQVLPYLLLGIAIGSFIYGFIPTDLIAKYAGAGKWYAIPVAAVIGIPLYIRAEAVIPLSAALVKKGMALGSVMALIIGSAGASLTEVILLKSIFKTPMIIAFVSVILTMAISAGFLYTFIFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYP9</accession>
    <name>D0YYP9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_002412</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002412"/>
    <dbReference type="EnsemblBacteria" id="EEZ41380">
        <property type="protein sequence ID" value="EEZ41380"/>
        <property type="gene ID" value="VDA_002412"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0531">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="72"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="108"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="159"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="212"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="242"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="284"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="308"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="351" mass="38253" checksum="9D7A2533C53C5AF7" modified="2010-01-19" version="1">MVTSVISMVLFAVATHISTKGASWLGKISEIVAYGVFALFAIYVFGALLALGGDHTPAQPITLEAMEPTVNWATLGIMCWIFQAAGGAETAAAYLNDVKGGHKSFIKVIIIAGLLIGGMYALGSLLVNVFVARDALTYSGGMVEIFTGMAQYFGISESLVGRFVGIVLFIAMFGSMMMWTAAPVKIHFSEIPKGVYGEKTTELNEHGVPVRAAWWQFAFVFVMLIVNGFGSESVQDMMNQAINLTAGTAMLPPIFIMVAYFVFRWKHDDTPRDFRMGSQKFGMAMVSVLIAIFVVSMTASAFPTGVDLVRAFFINVFMTAVFSGLAWWWISRFEAKQKKLAAKQVLKEAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYZ4</accession>
    <name>D0YYZ4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent)</fullName>
            <ecNumber evidence="4">5.4.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">VDA_002507</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:23536"/>
            <dbReference type="ChEBI" id="CHEBI:58225"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="EC" id="5.4.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.2" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300219.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002507"/>
    <dbReference type="EnsemblBacteria" id="EEZ41475">
        <property type="protein sequence ID" value="EEZ41475"/>
        <property type="gene ID" value="VDA_002507"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0033">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="637615at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004614">
        <property type="term" value="F:phosphoglucomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05801">
        <property type="entry name" value="PGM_like3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005845">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005846">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005843">
        <property type="entry name" value="A-D-PHexomutase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016066">
        <property type="entry name" value="A-D-PHexomutase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045244">
        <property type="entry name" value="PGM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005852">
        <property type="entry name" value="PGM_a-D-Glc-sp"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22573">
        <property type="entry name" value="PTHR22573"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02879">
        <property type="entry name" value="PGM_PMM_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02880">
        <property type="entry name" value="PGM_PMM_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00408">
        <property type="entry name" value="PGM_PMM_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="SSF53738"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="SSF55957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01132">
        <property type="entry name" value="pgm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00710">
        <property type="entry name" value="PGM_PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 14" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PGM_PMM_I" evidence="11">
        <location>
            <begin position="40"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_II" evidence="12">
        <location>
            <begin position="210"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_III" evidence="13">
        <location>
            <begin position="320"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_IV" evidence="10">
        <location>
            <begin position="488"/>
            <end position="538"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEZ41475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="548" mass="58955" checksum="6E4ADD83C8B1C76A" modified="2010-01-19" version="1">MAIHDRAGQRAQQSDLINIPALVANYFLIEPSADNAAQKVEFGTSGHRGTANKGTFNQHHIWAIAQAVAEVRQAHGVTGPLFLGKDTHALSEPAFISTLEVLVANGVKVIVQKDNGYTPTPGVSHSILCHNKASAEKADGIVITPSHNPPQDGGIKYNPVHGGPAEGELTTAIESRANEIIASGMQAVKRIAIEQALASDLVEERDLVTPYVEDLVNVVDMAAIQNANLTIGVDPLGGSGIEYWREIAKYYNLNITLVDESIDPSFRFMSLDKDGVIRMDCSSPYAMAGLLEYKDKYDLAFGNDPDYDRHGIVTPAGLMNPNHYLAVCIDYLYRHRAQWADGVAVGKTLVSSALIDRVVADLGRSLCEVPVGFKWFVDGLYSGELGFGGEESAGASFLRMDGTPWSTDKDGILLCLLAAEITAVTGKNPQQYYEELAAKHGASEYSRLQAVANKQQKAVLSKLSPEMVAAETLAGDVITARLTHAPGNGAAIGGLKVTTENGWFAARPSGTEDIYKIYCESFKGKEHLALIEKEAQEIVSKVFTDAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ72</accession>
    <name>D0YZ72_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Protein phosphatase CheZ</fullName>
            <ecNumber evidence="7">3.1.3.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 7">Chemotaxis protein CheZ</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_002585</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the CheZ family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.-" evidence="7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300399.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002585"/>
    <dbReference type="EnsemblBacteria" id="EEZ41553">
        <property type="protein sequence ID" value="EEZ41553"/>
        <property type="gene ID" value="VDA_002585"/>
    </dbReference>
    <dbReference type="GeneID" id="57341173"/>
    <dbReference type="eggNOG" id="COG3143">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1206193at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009288">
        <property type="term" value="C:bacterial-type flagellum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004721">
        <property type="term" value="F:phosphoprotein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097588">
        <property type="term" value="P:archaeal or bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050920">
        <property type="term" value="P:regulation of chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007439">
        <property type="entry name" value="Chemotax_Pase_CheZ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04344">
        <property type="entry name" value="CheZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002884">
        <property type="entry name" value="CheZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7" id="KW-0283">Flagellar rotation</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="site" description="Enhances dephosphorylation of CheY-P" evidence="8">
        <location>
            <position position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR002884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR002884-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="240" mass="27249" checksum="DFCFBA3644725830" modified="2010-01-19" version="1">MITLDQAKQLVCLLEDGQQTEANALMQMIIAETREPMYEEVGKITRQLHDSLTHFRLDPRLNDLATNEIPDARDRLSFVIDKTEAAANKTMDAVESLLPIADQLHETLLQVRPQWQRLMDGEINLAEFKLLCHDIDKLLMQVEGDSSEVRSQLTEILMAQDFQDLTGQIIRRVIALVQEVEERLIEILKAFGLEEQGPMSEAQQVERALRAEGPIVNTEKHDNVMSSQDDVDDLLSSLGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZK9</accession>
    <name>D0YZK9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Hypothetical trypsin-like serine protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_002722</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300818.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002722"/>
    <dbReference type="EnsemblBacteria" id="EEZ41690">
        <property type="protein sequence ID" value="EEZ41690"/>
        <property type="gene ID" value="VDA_002722"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020008">
        <property type="entry name" value="GlyGly_CTERM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03501">
        <property type="entry name" value="GlyGly_CTERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0720">Serine protease</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="5">
        <location>
            <begin position="36"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="323"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU363034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="369" mass="40470" checksum="759AB163673B4D3A" modified="2010-01-19" version="1">MKRSNYSFISQTLFRFALFWVMFFSSAVFALVTPKIVGGSSGASLPWQAYLKINSQGQTYTCGAVVIGSHTILTAAHCLEFNDKIVTPSQVSVWTGITQTSQASYSSSLPVKRIDLHPLFDSDTFINDIAVISLVDEVTSNAIPITLTQPDEQQEMDTQFALTWVTNGSREGNLLVSGWGSTDPTLNDTSGSSQLLATVLSGVPDSICRSLWGGFISLDESTQFLCAAATAPWKDQDSCLGDSGGPLIWQDPQHSNDSDYGLRLAGIVSFGDGCDGKRPGGYTEVSHYYSWIASHMDEELQLSNQAVFTENPFTRYDEDGDLLDEFQDALDDAQDGLQQLEDNIDKYTSGGSLSWFTLLGVMFLAWRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZP7</accession>
    <name>D0YZP7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002760</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300928.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002760"/>
    <dbReference type="EnsemblBacteria" id="EEZ41728">
        <property type="protein sequence ID" value="EEZ41728"/>
        <property type="gene ID" value="VDA_002760"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0223">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1863261at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="SSF75005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="297" mass="34626" checksum="C3E565EA442313B3" modified="2010-01-19" version="1">MTLLSRFTDQDFWRIGLINEHPLDVIEKGLSACNIQWFNFTDKDFEADPFVFVFENKSYIAYEIFDYSHGNGKIECVDFEGNRYNFFEDISNIVGHKSFPFVFEDDHELYCIVETSDLNEITLYKFDGVKFIKQKTLLSGSKFIDTCIKRIDDTFYLFTSTSDNAFQQQLYVSDSLLGDYTLHPSSPIANNKAFGRNGGPIIERNGQYYRVCQNCEITYGGSLKIMRITDISTTSYQEEFYKDVMPVEPYSDGIHTLSYWGNMTVIDSKNILTKYSNIYRKIKYLAMVKLKIEKPFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZR3</accession>
    <name>D0YZR3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Outer membrane protein assembly factor BamE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">bamE</name>
        <name evidence="6" type="ORF">VDA_002776</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the Bam complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the BamE family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002776"/>
    <dbReference type="EnsemblBacteria" id="EEZ41744">
        <property type="protein sequence ID" value="EEZ41744"/>
        <property type="gene ID" value="VDA_002776"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2913">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043165">
        <property type="term" value="P:Gram-negative-bacterium-type cell outer membrane assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051205">
        <property type="term" value="P:protein insertion into membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1450.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00925">
        <property type="entry name" value="OM_assembly_BamE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026592">
        <property type="entry name" value="BamE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037873">
        <property type="entry name" value="BamE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007450">
        <property type="entry name" value="Lipoprotein_SmpA/OmlA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37482">
        <property type="entry name" value="PTHR37482"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04355">
        <property type="entry name" value="SmpA_OmlA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="6" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0732">Signal</keyword>
    <feature type="domain" description="SmpA_OmlA" evidence="5">
        <location>
            <begin position="10"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="94" mass="10913" checksum="A2AED3146AE7E17A" modified="2010-01-19" version="1">MVYQITIDQGNYVEQKNVDALRMGMTQEQVQYVLGTPMLVDPSYPKTWNYIFYVKPGHEKPEQKNLFLNFDDQGRLVSMSGDFKQGPNFTTPMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZY7</accession>
    <name>D0YZY7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Riboflavin biosynthesis protein</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="12">Riboflavin kinase</fullName>
                <ecNumber evidence="12">2.7.1.26</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="12">Flavokinase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="12">FMN adenylyltransferase</fullName>
                <ecNumber evidence="12">2.7.7.2</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="12">FAD pyrophosphorylase</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="12">FAD synthase</fullName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="14" type="ORF">VDA_002850</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 12">
            <text>ATP + FMN + H(+) = diphosphate + FAD</text>
            <dbReference type="Rhea" id="RHEA:17237"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="EC" id="2.7.7.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>ATP + riboflavin = ADP + FMN + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14357"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57986"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.26"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4 12">Cofactor biosynthesis; FAD biosynthesis; FAD from FMN: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5 12">Cofactor biosynthesis; FMN biosynthesis; FMN from riboflavin (ATP route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the ribF family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.26" evidence="12"/>
    <dbReference type="EC" id="2.7.7.2" evidence="12"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301192.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002850"/>
    <dbReference type="EnsemblBacteria" id="EEZ41818">
        <property type="protein sequence ID" value="EEZ41818"/>
        <property type="gene ID" value="VDA_002850"/>
    </dbReference>
    <dbReference type="GeneID" id="57340863"/>
    <dbReference type="eggNOG" id="COG0196">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1504821at2"/>
    <dbReference type="UniPathway" id="UPA00276">
        <property type="reaction ID" value="UER00406"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00277">
        <property type="reaction ID" value="UER00407"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003919">
        <property type="term" value="F:FMN adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008531">
        <property type="term" value="F:riboflavin kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006747">
        <property type="term" value="P:FAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009398">
        <property type="term" value="P:FMN biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02064">
        <property type="entry name" value="FAD_synthetase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015864">
        <property type="entry name" value="FAD_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023468">
        <property type="entry name" value="Riboflavin_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002606">
        <property type="entry name" value="Riboflavin_kinase_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015865">
        <property type="entry name" value="Riboflavin_kinase_bac/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023465">
        <property type="entry name" value="Riboflavin_kinase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22749">
        <property type="entry name" value="PTHR22749"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06574">
        <property type="entry name" value="FAD_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01687">
        <property type="entry name" value="Flavokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004491">
        <property type="entry name" value="FAD_Synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00904">
        <property type="entry name" value="Flavokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82114">
        <property type="entry name" value="SSF82114"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00083">
        <property type="entry name" value="ribF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 12" id="KW-0274">FAD</keyword>
    <keyword evidence="6 12" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7 12" id="KW-0288">FMN</keyword>
    <keyword evidence="12 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="9 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12 14" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Flavokinase" evidence="13">
        <location>
            <begin position="183"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR004491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEZ41818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="320" mass="35906" checksum="B9A7FCE897CC9B42" modified="2010-01-19" version="1">MELIRGIYNIRPRHHGCVLTIGNFDGVHLGHQAVLKQLIVKAHEMSLPATVMCFEPQPLEMFAPSRAPARLTRFRDKYLQLKNVGVERLLCVNFNAHFANLTAEEFVRRLLVEQLGVKFLVVGDDFRFGKDRVGNFDMLVAAGKQYGFEVVSTQSFCVSKQRVSSTAIRQALASDNLVDAETMLGRPYSINGRVSHGRKLGRTIGFPTANVPLKRRVSPVSGVYAVEVYGVGEKPIPGVANIGHRPTVKGVRQQLEVHLFDFHSDLYGRQIEVVLRHKLRDEQKFESFDALKAQIEHDAQSARLWLAEANNVQLRPSNGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZZ0</accession>
    <name>D0YZZ0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional activator NhaR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002853</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301200.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41821">
        <property type="protein sequence ID" value="EEZ41821"/>
        <property type="gene ID" value="VDA_002853"/>
    </dbReference>
    <dbReference type="GeneID" id="57340859"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="990666at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="4"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="295" mass="34108" checksum="FF0565A6362CA0FA" modified="2010-01-19" version="1">MSHLNYNHLYYFWMVCKQGSVTKAADALFLAPQTVTGQIRALEERLKGKLTKRVGRNIEPTELGQLVFKYADRMFDLSYEMLDIVNYTQRENQLLEVGVADALSKRLVSKILLVGMPEDEKIHLRCYESTHEMLLERLSQHKLDMILSDCPVDSTQSPGLYSKKLGESSMSFFCQTPEHPVDFPACIEDYKLLVPGPRTAMGRKLHQWFEQQGLTPNILGEFDDAALMKAFGAYHRSMFVAPSIYAEELEESNKFCELKRVREIKEEYYVIFAERMIMHPAVKTICETDFGYLFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0B7</accession>
    <name>D0Z0B7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ThrE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002980</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301451.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002980"/>
    <dbReference type="EnsemblBacteria" id="EEZ41948">
        <property type="protein sequence ID" value="EEZ41948"/>
        <property type="gene ID" value="VDA_002980"/>
    </dbReference>
    <dbReference type="GeneID" id="57340708"/>
    <dbReference type="eggNOG" id="COG2966">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1425894at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010619">
        <property type="entry name" value="ThrE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06738">
        <property type="entry name" value="ThrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="145"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="200"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="232"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="ThrE" evidence="2">
        <location>
            <begin position="19"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="262" mass="28806" checksum="262C45C179207E4F" modified="2010-01-19" version="1">MPDHEGCLSEPEQREISHLAVTAGQKLLQHGAESTLIADVTRRIGLALGVDTVEVSLSASSMVITTRYQGRCITTTRRCQDGGINMQVVTEIQRICILAERGLISVKEVHHRLEHLKATRYNRYLVVFMIGLSCASFSRLAGGDWPVFWLTFFASSIGMFVRQEIAHCQFNPLINFGITAFVTTLISGFGQVYQVGDTPFIAMASSVLMLVPGFPLINSIADMVKGYVNMGIARWAMATLLTLSTCMGIVAAMNVLDVWGWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0D1</accession>
    <name>D0Z0D1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hypothetical phage shock protein E</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002994</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002994"/>
    <dbReference type="EnsemblBacteria" id="EEZ41962">
        <property type="protein sequence ID" value="EEZ41962"/>
        <property type="gene ID" value="VDA_002994"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0607">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="2"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="61" mass="7009" checksum="A405829EDD3F769B" modified="2010-01-19" version="1">MNIPFDQIAQLEAQVKEKDRPILLYCRSGQRARIAEQQLNALGYPNTFNGMSYQQLLQAKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0F5</accession>
    <name>D0Z0F5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003019</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003019"/>
    <dbReference type="EnsemblBacteria" id="EEZ41986">
        <property type="protein sequence ID" value="EEZ41986"/>
        <property type="gene ID" value="VDA_003019"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4775">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019934" evidence="1">
        <location>
            <begin position="27"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="426" mass="47825" checksum="3E7DDF08E867D8E0" modified="2010-01-19" version="1">MRLMTSHISKAVAVATAFFCFPTVGAASGDDKQEDKNSSWYHDAAAVPFAFSTDSMGFSIGLAGVVKGAGQPQASLLGAGLVTNKGTWMTYLGAYNFAPSEQGRWLLGTELYSANYQDFDYFLGAGAGNDSSTDDAVIADANEAWYQLSARYILPWGSAKQEPIKSALIPTRKITGHAPWNSGVSSIEFRPFYQSRQFEHSPSLPTTQFSTADSVWGLETRLDWDNQNNTRNPTEGSHTQVKLTYDPGASERPSWWKWEINQSWFWNLGQWGDLFDQQVIAFNVYTADTPSWNNRESVSGQEQYQRPPEFAAVRLGGLYRLRSYQGGRFAGRSALSYSLEYRVMPEWQPLGGWPVFDWYDVPWWQWVAFVDAGRVADSYSLSTLHQDMKWSAGGAMRFQVEGVVVRAEMAWGQEESTFRVMVNQPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0I1</accession>
    <name>D0Z0I1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Carbonic anhydrase</fullName>
            <ecNumber evidence="3 8">4.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_003045</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Reversible hydration of carbon dioxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>H(+) + hydrogencarbonate = CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:10748"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="EC" id="4.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the alpha-carbonic anhydrase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.1" evidence="3 8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003045"/>
    <dbReference type="EnsemblBacteria" id="EEZ42012">
        <property type="protein sequence ID" value="EEZ42012"/>
        <property type="gene ID" value="VDA_003045"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3338">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004089">
        <property type="term" value="F:carbonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03124">
        <property type="entry name" value="alpha_CA_prokaryotic_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041891">
        <property type="entry name" value="Alpha_CA_prokaryot-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001148">
        <property type="entry name" value="CA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036398">
        <property type="entry name" value="CA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023561">
        <property type="entry name" value="Carbonic_anhydrase_a-class"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018338">
        <property type="entry name" value="Carbonic_anhydrase_a-class_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18952">
        <property type="entry name" value="PTHR18952"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00194">
        <property type="entry name" value="Carb_anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01057">
        <property type="entry name" value="Carb_anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51069">
        <property type="entry name" value="SSF51069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00162">
        <property type="entry name" value="ALPHA_CA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51144">
        <property type="entry name" value="ALPHA_CA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="6 8" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025092357" description="Carbonic anhydrase" evidence="8">
        <location>
            <begin position="24"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-carbonic anhydrase" evidence="9">
        <location>
            <begin position="24"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU367011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ42012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="242" mass="26690" checksum="90AE06C890EFD7A1" modified="2010-01-19" version="1">MKKITASATCLSLALLFAGQVQAEGWGYGEANGPEHWGEVAPLCATGVNQSPINITKATQANLLPLRIDYQGKVTQLVNNGHTIEALVSGKNDVIINGDTYHLKQFHFHTPSENLIDGKQYPLEAHFVNADDKGKLAVISVMFEIGPRANSDLDALLNEIPEKGQTIEIKQDLTPGALLPRDREYYQFNGSLTTPPCTEGVRWYVMQEHQTSSKEQTEMLHAVMGNNNRPTQPLNARVILDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0M4</accession>
    <name>D0Z0M4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">D-3-phosphoglycerate dehydrogenase</fullName>
            <ecNumber evidence="2">1.1.1.95</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003088</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.95" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301824.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003088"/>
    <dbReference type="EnsemblBacteria" id="EEZ42055">
        <property type="protein sequence ID" value="EEZ42055"/>
        <property type="gene ID" value="VDA_003088"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0111">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1435073at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004617">
        <property type="term" value="F:phosphoglycerate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2-Hacid_dh_C" evidence="1">
        <location>
            <begin position="96"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="303" mass="34368" checksum="521DD46547DC555F" modified="2010-01-19" version="1">MHKLAIVSRQQQAYERLLAATPLPLLEITNDPKQATIILADPPEIAAYLDDYPQLKWLQSTFAGIDALTKPQLRQDYHLTNVRGCFGPLIAEYVFGQWLSHSRHFPLYSKQQQQHQWHPLPYQSIAGKTLVIIGTGSIGQQLAQVAKAFHCQVIGVNRHGNSPCELFDRIYATAQLSQALEQADVIVSVVPATSDTTDLFNHQTFSHCHQALLFNVGRGNAVNIADLYQALDRDQIHHAYLDVFKTEPLEQNSKLWDHPQISITPHIAAESFPAQVFEIFKLNYIKWLNNQTLNYQIDFSKGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0M9</accession>
    <name>D0Z0M9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L7/L12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rplL</name>
        <name evidence="7" type="ORF">VDA_003093</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bL12 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301839.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003093"/>
    <dbReference type="EnsemblBacteria" id="EEZ42060">
        <property type="protein sequence ID" value="EEZ42060"/>
        <property type="gene ID" value="VDA_003093"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0222">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1822695at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00387">
        <property type="entry name" value="Ribosomal_L7_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00368">
        <property type="entry name" value="Ribosomal_L7_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000206">
        <property type="entry name" value="Ribosomal_L7/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014719">
        <property type="entry name" value="Ribosomal_L7/12_C/ClpS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013823">
        <property type="entry name" value="Ribosomal_L7/L12_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008932">
        <property type="entry name" value="Ribosomal_L7/L12_oligo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036235">
        <property type="entry name" value="Ribosomal_L7/L12_oligo_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45987">
        <property type="entry name" value="PTHR45987"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00542">
        <property type="entry name" value="Ribosomal_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16320">
        <property type="entry name" value="Ribosomal_L12_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48300">
        <property type="entry name" value="SSF48300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54736">
        <property type="entry name" value="SSF54736"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00855">
        <property type="entry name" value="L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal_L12_N" evidence="6">
        <location>
            <begin position="4"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L12" evidence="5">
        <location>
            <begin position="55"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ42060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="121" mass="12253" checksum="BF1732851F5C2EC5" modified="2010-01-19" version="1">MSITNEQILDAVAEMSVMQVVELIEAMEEKFGVTAAAAVVAGGAAAEAAEEQTEFDVILTACGANKVAVIKAVRGATGLGLKEAKAVVDGAPAPLKEGVEKAEAEALKAQLEEAGASVEIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0N6</accession>
    <name>D0Z0N6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Type III pantothenate kinase</fullName>
            <ecNumber evidence="6">2.7.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">PanK-III</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Pantothenic acid kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">coaX</name>
        <name evidence="7" type="ORF">VDA_003100</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>(R)-pantothenate + ATP = (R)-4'-phosphopantothenate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16373"/>
            <dbReference type="ChEBI" id="CHEBI:10986"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29032"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.33"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>NH4(+)</name>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
        </cofactor>
        <cofactor evidence="6">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
        <text evidence="6">A monovalent cation. Ammonium or potassium.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 6">Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 1/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the type III pantothenate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.33" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301858.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003100"/>
    <dbReference type="EnsemblBacteria" id="EEZ42067">
        <property type="protein sequence ID" value="EEZ42067"/>
        <property type="gene ID" value="VDA_003100"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1521">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2039419at2"/>
    <dbReference type="UniPathway" id="UPA00241">
        <property type="reaction ID" value="UER00352"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004594">
        <property type="term" value="F:pantothenate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01274">
        <property type="entry name" value="Pantothen_kinase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004619">
        <property type="entry name" value="Type_III_PanK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34265">
        <property type="entry name" value="PTHR34265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03309">
        <property type="entry name" value="Pan_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00671">
        <property type="entry name" value="baf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6" id="KW-0173">Coenzyme A biosynthesis</keyword>
    <keyword evidence="4 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0630">Potassium</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="98"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="100"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="6"/>
            <end position="13"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>a monovalent cation</name>
            <dbReference type="ChEBI" id="CHEBI:60242"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ42067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="244" mass="27213" checksum="05C6416D65B509A6" modified="2010-01-19" version="1">MQLLIEAGNTYVKVAQLFKNGQLELLGKYSSRKLEMVLEPLLDKKEIHRIVFASVGPVEIDNSIQRISQLSNIPVIQVKTPSHDFGVKNAYSEYQYLGIDRWLTLVAIHQIYQQPTVIVDIGTALTFDVLAEDGMHLGGWIAPGYQLMMKSVLENTTKVFSDRDHVDSLELATNTADGLKNGCRAALLGLIEYGLKQAHEDLGVEPHVILCGGGVIHLPKKWAQQYTHRSDLVLEGLALYAKHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0P5</accession>
    <name>D0Z0P5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA/tmRNA (uracil-C(5))-methyltransferase</fullName>
            <ecNumber evidence="4">2.1.1.35</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">tRNA (uracil(54)-C(5))-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA(m5U54)-methyltransferase</fullName>
            <shortName evidence="4">RUMT</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tmRNA (uracil(341)-C(5))-methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">trmA</name>
        <name evidence="7" type="ORF">VDA_003109</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>S-adenosyl-L-methionine + uridine(341) in tmRNA = 5-methyluridine(341) in tmRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:43612"/>
            <dbReference type="Rhea" id="RHEA-COMP:10630"/>
            <dbReference type="Rhea" id="RHEA-COMP:10631"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74447"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>S-adenosyl-L-methionine + uridine(54) in tRNA = 5-methyluridine(54) in tRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42712"/>
            <dbReference type="Rhea" id="RHEA-COMP:10167"/>
            <dbReference type="Rhea" id="RHEA-COMP:10193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74447"/>
            <dbReference type="EC" id="2.1.1.35"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.35" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301885.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003109"/>
    <dbReference type="EnsemblBacteria" id="EEZ42076">
        <property type="protein sequence ID" value="EEZ42076"/>
        <property type="gene ID" value="VDA_003109"/>
    </dbReference>
    <dbReference type="GeneID" id="57340666"/>
    <dbReference type="eggNOG" id="COG2265">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1421660at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030697">
        <property type="term" value="F:S-adenosylmethionine-dependent tRNA (m5U54) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01011">
        <property type="entry name" value="RNA_methyltr_TrmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030390">
        <property type="entry name" value="MeTrfase_TrmA_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030391">
        <property type="entry name" value="MeTrfase_TrmA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011869">
        <property type="entry name" value="TrmA_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010280">
        <property type="entry name" value="U5_MeTrfase_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47790">
        <property type="entry name" value="PTHR47790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05958">
        <property type="entry name" value="tRNA_U5-meth_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02143">
        <property type="entry name" value="trmA_only"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51687">
        <property type="entry name" value="SAM_MT_RNA_M5U"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01230">
        <property type="entry name" value="TRMA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01231">
        <property type="entry name" value="TRMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4 5" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <feature type="active site" evidence="6">
        <location>
            <position position="326"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4 5">
        <location>
            <position position="326"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="360"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="218"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="223"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="301"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ42076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="368" mass="43076" checksum="2DB348CF99678901" modified="2010-01-19" version="1">MASSVFNTADYQHQLDEKAQRIQNIFADFDTPELEVYASPAEHYRMRAEFRVWHEGEDLYYIMFNQQTREKYRVDQFPAASRLINDLMPLLIEAVKPHRSLRHKLFQVDFLSTLSGEILVSMLYHRQLDEEWETLAKALKQQLNDEGFKLNIIGRARKQKKVLDQEFVIEKLNVFDRTLTYKQVENSFTQPNGTVAQKMLEWAVDCTRDSQGDLLELYCGNGNFSLALAQNFERVLATELAKPSVESAQYNIAVNNIDNVQIIRMSAEEFTEAMEGRREFRRLKDNNIDLQSYNCNTIFVDPPRSGMDEGTCRMVQGYERIMYISCNPETLKENLDILSETHRITRFALFDQFPYTHHMEAGVFLERK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0T7</accession>
    <name>D0Z0T7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA helicase</fullName>
            <ecNumber evidence="3">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_003151</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the helicase family. UvrD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003151"/>
    <dbReference type="EnsemblBacteria" id="EEZ42118">
        <property type="protein sequence ID" value="EEZ42118"/>
        <property type="gene ID" value="VDA_003151"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0210">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006268">
        <property type="term" value="P:DNA unwinding involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013986">
        <property type="entry name" value="DExx_box_DNA_helicase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005753">
        <property type="entry name" value="DNA_helicase_ATP-dep_UvrD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014017">
        <property type="entry name" value="DNA_helicase_UvrD-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000212">
        <property type="entry name" value="DNA_helicase_UvrD/REP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014016">
        <property type="entry name" value="UvrD-like_ATP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11070">
        <property type="entry name" value="PTHR11070"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00580">
        <property type="entry name" value="UvrD-helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13361">
        <property type="entry name" value="UvrD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01075">
        <property type="entry name" value="uvrD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51198">
        <property type="entry name" value="UVRD_HELICASE_ATP_BIND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51217">
        <property type="entry name" value="UVRD_HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 9" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UvrD-like helicase ATP-binding" evidence="7">
        <location>
            <begin position="1"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="UvrD-like helicase C-terminal" evidence="8">
        <location>
            <begin position="250"/>
            <end position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ42118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="686" mass="78814" checksum="263D85BAA9961082" modified="2010-01-19" version="1">MLVHRIAWLIAIEQASPYSIMSVTFTNKAAAEMRGRINELMEGSTFGMWNGTFHGLCHRILRAHYLDARLPEDFNILDSDDQLRLLRRLIKAQNLDEKQWPPRQGAWYINGKKDEGLRPHQIETFNDPVEQTWQRIYAAYQEACDRAGLVDFAELLLRAFELVRDNKFIREHYQARFKHILVDEFQDTNSIQFAWLRLMAGPDCHVMIVGDDDQSIYGWRGAKVENISRFLREFHDAKSIFLEQNYRSTGNILKAANELIANNNERMGKNLWTDGADGDRISLYSAFNELDEARFAVGKIKEWRDQGGTLNEVAFLYRSNAQSRVLEEALIQAGMPYRIYGGMRFFERQEIKDALSYLRLISNRNDDTAFERVVNTPTRGIGDRTLETIRLAARDRSMTMWQASIALLDDQVLAGRAANALRRFIELVDALEDDTAELALYQQTDDVIRNSGLRAMYEQEKGEKAQARIENLEELVTATRQFEIPEEAQEMTHLAAFLSHAALEAGEGQADDFEDAVQLMTMHSAKGLEFPLVFMVGMEEGMFPSSRTTEEVGRLEEERRLCYVGMTRAMQKLYLTHAEMRRLYGKDNFHKPSRFLKEIPEHFIDEVRMKAQVSRPVSTGRFSQTTVNENFNQTGFSLGQRVEHPTFGEGTIINYEGSGPQSRVQVAFNGQGIKWLVTQYAKLTAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0U1</accession>
    <name>D0Z0U1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Diaminopimelate epimerase</fullName>
            <shortName evidence="8">DAP epimerase</shortName>
            <ecNumber evidence="4 8">5.1.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">PLP-independent amino acid racemase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">dapF</name>
        <name evidence="10" type="ORF">VDA_003155</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>(2S,6S)-2,6-diaminoheptanedioate = meso-2,6-diaminoheptanedioate</text>
            <dbReference type="Rhea" id="RHEA:15393"/>
            <dbReference type="ChEBI" id="CHEBI:57609"/>
            <dbReference type="ChEBI" id="CHEBI:57791"/>
            <dbReference type="EC" id="5.1.1.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; DL-2,6-diaminopimelate from LL-2,6-diaminopimelate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the diaminopimelate epimerase family.</text>
    </comment>
    <dbReference type="EC" id="5.1.1.7" evidence="4 8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302025.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003155"/>
    <dbReference type="EnsemblBacteria" id="EEZ42122">
        <property type="protein sequence ID" value="EEZ42122"/>
        <property type="gene ID" value="VDA_003155"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0253">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1921631at2"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00025"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008837">
        <property type="term" value="F:diaminopimelate epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00197">
        <property type="entry name" value="DAP_epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018510">
        <property type="entry name" value="DAP_epimerase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001653">
        <property type="entry name" value="DAP_epimerase_DapF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31689">
        <property type="entry name" value="PTHR31689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01678">
        <property type="entry name" value="DAP_epimerase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00652">
        <property type="entry name" value="DapF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01326">
        <property type="entry name" value="DAP_EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 8 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6 8" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="76"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="210"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="220"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="75"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="75"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="219"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Could be important to modulate the pK values of the two catalytic cysteine residues" evidence="8">
        <location>
            <position position="161"/>
        </location>
    </feature>
    <feature type="site" description="Could be important to modulate the pK values of the two catalytic cysteine residues" evidence="8">
        <location>
            <position position="210"/>
        </location>
    </feature>
    <feature type="site" description="Important for dimerization" evidence="8">
        <location>
            <position position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ42122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="276" mass="30287" checksum="1411D55D3C6E875F" modified="2010-01-19" version="1">MQINFSKMHGLGNDFMVVDAVTQNVFFSPDMVRRLADRHRGIGFDQLLIVEPPYDPETDFHYRIFNADGSEVEQCGNGARCFARFVSMKGLTNKYHISVSTKAGKMLLKLENDDQVTVNMGVPIFDPAKIPFRANQAEKTYILRAGDQTVFCGAASMGNPHCVTVVDDVLTADVETLGPLLESHERFPERVNVGFMQVISRSEVKLRVYERGAGETQACGSGACAAVAIGRQQGLLDEEVTVSLPGGDLRIRWNGNGSNLFMTGPVAHVFDGQVLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0Z0</accession>
    <name>D0Z0Z0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Ribosomal RNA small subunit methyltransferase B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_003204</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003204"/>
    <dbReference type="EnsemblBacteria" id="EEZ42171">
        <property type="protein sequence ID" value="EEZ42171"/>
        <property type="gene ID" value="VDA_003204"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0144">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008649">
        <property type="term" value="F:rRNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018314">
        <property type="entry name" value="Fmu/NOL1/Nop2p_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001678">
        <property type="entry name" value="MeTrfase_RsmB/NOP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023267">
        <property type="entry name" value="RCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004573">
        <property type="entry name" value="rRNA_ssu_MeTfrase_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22807">
        <property type="entry name" value="PTHR22807"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01189">
        <property type="entry name" value="Methyltr_RsmB-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02008">
        <property type="entry name" value="RCMTFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00563">
        <property type="entry name" value="rsmB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01153">
        <property type="entry name" value="NOL1_NOP2_SUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51686">
        <property type="entry name" value="SAM_MT_RSMB_NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 5 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SAM_MT_RSMB_NOP" evidence="7">
        <location>
            <begin position="44"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="5">
        <location>
            <begin position="134"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="255"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ42171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="308" mass="34402" checksum="6755A2749AD1EA8A" modified="2010-01-19" version="1">MRNYQRQQQELDAQAVSHDAGKYGHPSWLLKLLKQAYPNDVDAICAANNTKAPMWLRVNRQHHNRDEYRKLLDAEGIATELHPQAGDALRLLSPCDVYKLPGFEQGWVSVQDAAAQLAIEYLQPQAGELILDCCAAPGGKTAHILEHVPSAQVVAIDCDEHRLARVHDNLQRLNLQAKVLCADARYPEKWWDGDKFDRILLDAPCSATGVIRRHPDIKWLRRGEDIAALAQLQAEIFDAMWLQLKSGGTLVYATCSITPQENRDQVSAFLTRTADATLVGSEATNPGRQILPGEENMDGFYYAVLQKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-06-02" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0Z6</accession>
    <name>D0Z0Z6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ42177">
        <property type="protein sequence ID" value="EEZ42177"/>
        <property type="gene ID" value="VDA_003210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="57" mass="6395" checksum="0BEEF9CD533526F2" modified="2010-01-19" version="1">MRPASFARFAPRSPSRFRTTSHAPRFQAKTKTAQVHTLPNQETTVETHTTTEDPKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z144</accession>
    <name>D0Z144_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">3-ketoacyl-CoA thiolase</fullName>
            <ecNumber evidence="8">2.3.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Acetyl-CoA acyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Beta-ketothiolase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Fatty acid oxidation complex subunit beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">fadA</name>
        <name evidence="13" type="ORF">VDA_003258</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>acetyl-CoA + an acyl-CoA = a 3-oxoacyl-CoA + CoA</text>
            <dbReference type="Rhea" id="RHEA:21564"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
            <dbReference type="EC" id="2.3.1.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Lipid metabolism; fatty acid beta-oxidation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8 10">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.16" evidence="8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003258"/>
    <dbReference type="EnsemblBacteria" id="EEZ42225">
        <property type="protein sequence ID" value="EEZ42225"/>
        <property type="gene ID" value="VDA_003258"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0183">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00659"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003988">
        <property type="term" value="F:acetyl-CoA C-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01620">
        <property type="entry name" value="FadA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012805">
        <property type="entry name" value="FadA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020615">
        <property type="entry name" value="Thiolase_acyl_enz_int_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020610">
        <property type="entry name" value="Thiolase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020613">
        <property type="entry name" value="Thiolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02445">
        <property type="entry name" value="fadA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00098">
        <property type="entry name" value="THIOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00737">
        <property type="entry name" value="THIOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00099">
        <property type="entry name" value="THIOLASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 8" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5 8" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="6 8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase_N" evidence="11">
        <location>
            <begin position="5"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase_C" evidence="12">
        <location>
            <begin position="264"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="8 9">
        <location>
            <position position="92"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8 9">
        <location>
            <position position="344"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8 9">
        <location>
            <position position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01620"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000429-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ42225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="388" mass="41353" checksum="EDEEF5C0A067B6B4" modified="2010-01-19" version="1">MMNNVVIVDCIRTPMGRSKQGAFRHVRAEDLSAHLMSGLLERNPQLQPEQIEDIYWGCVQQTLEQGFNIARNAALLADLPHTVGATTVNRLCGSSMQALHDATRSIMVGDGDICLVGGVEHMGHVPMNHGVDFHPGLSKTVAKAAGMMGLTAEMLGRMYGISREMQDAFAARSHQRAHAATIEGRFCHEILPTLGHDSQGNLIKLTQDEVIRPETTIESLSALRPVFDPVNGTVTAGSSSALSDGASAMLIMSEEKANQLGLSIRARIKSMAIAGCDPSIMGFGPVPASQKALQRAGLTMKDIDIVELNEAFAAQSLPCVKELGLLDMMDEKVNLNGGAIALGHPLGCSGTRISTTLINLMEQQGAQFGLATMCIGLGQGIATVFERV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z149</accession>
    <name>D0Z149_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Ketol-acid reductoisomerase (NADP(+))</fullName>
            <shortName evidence="10">KARI</shortName>
            <ecNumber evidence="10">1.1.1.86</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Acetohydroxy-acid isomeroreductase</fullName>
            <shortName evidence="10">AHIR</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Alpha-keto-beta-hydroxylacyl reductoisomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ilvC</name>
        <name evidence="14" type="ORF">VDA_003263</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>(2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = (2S)-2-acetolactate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:22068"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:49072"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58476"/>
            <dbReference type="EC" id="1.1.1.86"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>(2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) = (S)-2-ethyl-2-hydroxy-3-oxobutanoate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:13493"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:49256"/>
            <dbReference type="ChEBI" id="CHEBI:49258"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.86"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="10">Binds 2 magnesium ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 2/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 2/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 10 11">Belongs to the ketol-acid reductoisomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.86" evidence="10"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302325.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003263"/>
    <dbReference type="EnsemblBacteria" id="EEZ42230">
        <property type="protein sequence ID" value="EEZ42230"/>
        <property type="gene ID" value="VDA_003263"/>
    </dbReference>
    <dbReference type="GeneID" id="57340311"/>
    <dbReference type="eggNOG" id="COG0059">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="188901at2"/>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00056"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004455">
        <property type="term" value="F:ketol-acid reductoisomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00435">
        <property type="entry name" value="IlvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013023">
        <property type="entry name" value="KARI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000506">
        <property type="entry name" value="KARI_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013116">
        <property type="entry name" value="KARI_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21371">
        <property type="entry name" value="PTHR21371"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01450">
        <property type="entry name" value="IlvC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07991">
        <property type="entry name" value="IlvN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00465">
        <property type="entry name" value="ilvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51851">
        <property type="entry name" value="KARI_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51850">
        <property type="entry name" value="KARI_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10 11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9 10 11" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="14" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 10 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0521">NADP</keyword>
    <keyword evidence="8 10 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="KARI N-terminal Rossmann" evidence="12">
        <location>
            <begin position="14"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="KARI C-terminal knotted" evidence="13">
        <location>
            <begin position="209"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="KARI C-terminal knotted" evidence="13">
        <location>
            <begin position="346"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="132"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="45"/>
            <end position="48"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="108"/>
            <end position="110"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 11">
        <location>
            <position position="217"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10 11">
        <location>
            <position position="221"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="278"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 11">
        <location>
            <position position="389"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 11">
        <location>
            <position position="393"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 11">
        <location>
            <position position="414"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEZ42230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="495" mass="55018" checksum="444AA255D42D7839" modified="2010-01-19" version="1">MANYFNTLNLREQLDQLGRCRFMAREEFTAEADYLKGKQVVIVGCGAQGLNQGLNMRDSGLNVAYALRQVAIDEQRQSYRNAKDNGFEVGSYEQLIPQADLVINLTPDKQHTNVVNAVMPLMKQGATLGYSHGFNIVEEGMQVRSDLTVVMVAPKCPGTEVREEYKRGFGVPTLIAVHPENDPNGEGLAIAKAWAAATGGHRAGVLESSFVAEVKSDLMGEQTILCGMLQAGSIVCYEKMIADGIEPDYAGKLLQYGWETITEALKFGGITHMMDRLSNPAKVRAFELSEELKDLMRPLYNKHMDDIISGHFSATMMADWANDDINLLTWRNETGETAFENYPSSNLHIEEQEYFDNGILMVAMVRAGVELAFEAMTASGIIDESAYYESLHELPLIANTIARKRLYEMNVVISDTAEYGNYLFANVAVPLLREKFMAKVSTEDIGRGLSSHSQWADNQTLIEVNQTIRQHPVEVIGHTLRGYMTDMKRIAVGGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1D6</accession>
    <name>D0Z1D6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphopantetheine adenylyltransferase</fullName>
            <ecNumber evidence="6">2.7.7.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Dephospho-CoA pyrophosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Pantetheine-phosphate adenylyltransferase</fullName>
            <shortName evidence="6">PPAT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">coaD</name>
        <name evidence="8" type="ORF">VDA_003350</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>(R)-4'-phosphopantetheine + ATP + H(+) = 3'-dephospho-CoA + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:19801"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57328"/>
            <dbReference type="ChEBI" id="CHEBI:61723"/>
            <dbReference type="EC" id="2.7.7.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6">Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 4/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the bacterial CoaD family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.3" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302549.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003350"/>
    <dbReference type="EnsemblBacteria" id="EEZ42317">
        <property type="protein sequence ID" value="EEZ42317"/>
        <property type="gene ID" value="VDA_003350"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0669">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1846503at2"/>
    <dbReference type="UniPathway" id="UPA00241">
        <property type="reaction ID" value="UER00355"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004595">
        <property type="term" value="F:pantetheine-phosphate adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02163">
        <property type="entry name" value="PPAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00151">
        <property type="entry name" value="PPAT_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001980">
        <property type="entry name" value="PPAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21342:SF1">
        <property type="entry name" value="PTHR21342:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01467">
        <property type="entry name" value="CTP_transf_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01020">
        <property type="entry name" value="LPSBIOSNTHSS"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01510">
        <property type="entry name" value="coaD_prev_kdtB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0173">Coenzyme A biosynthesis</keyword>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 6 8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CTP_transf_like" evidence="7">
        <location>
            <begin position="6"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="10"/>
            <end position="11"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="18"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="89"/>
            <end position="91"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="124"/>
            <end position="130"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="6">
        <location>
            <position position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00029346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ42317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="162" mass="18191" checksum="A9F0EDFE9E933167" modified="2010-01-19" version="1">MTTRVIYPGTFDPITNGHLDLIERAAAMFDTVIVGVAYNPTKKPLFDLDERVALAQSVTQHLPNVEIVGFSGLLVNFAKEHNANVLVRGLRAVSDFEYEFQLANMNRRLMPELETVFLTPAEENSFISSTIVKEVALHKGDVSQFVPQEVSIQLYKKLAFKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1T3</accession>
    <name>D0Z1T3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MSHA biogenesis protein MshE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_003497</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GSP E family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303611.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003497"/>
    <dbReference type="EnsemblBacteria" id="EEZ42464">
        <property type="protein sequence ID" value="EEZ42464"/>
        <property type="gene ID" value="VDA_003497"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2804">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="749544at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001482">
        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037257">
        <property type="entry name" value="T2SS_E_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007831">
        <property type="entry name" value="T2SS_GspE_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00437">
        <property type="entry name" value="T2SSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05157">
        <property type="entry name" value="T2SSE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160246">
        <property type="entry name" value="SSF160246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00662">
        <property type="entry name" value="T2SP_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T2SP_E" evidence="2">
        <location>
            <begin position="382"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ42464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="571" mass="63631" checksum="F6B3DF8AD9E900A6" modified="2010-01-19" version="1">MSLRLRKRLGDLLVEENIIAQSELEQALAEQHNTGRKLGDTLISMGFISEQQMLEFLSRQLGIPLVNLSRIKIDSDAVSLLSEVHARRLRALAIGRNGDTVRVAMSDPADLTAQESVYDQLHGYQVELVIASETQLLAAFDRYYRRTKEIASFAEQLKAEHQVQNPFSFGFDEAVDNDEVTVVKLINTLFEDAIQVGASDIHIEPDEDVLRIRQRIDGVLHETVLQEKSIASALVLRLKLMSGLDISEKRLPQDGRFNIKVKEHSVDIRISTMPVQHGESVVMRLLDQSAGILSLEQVGMPAEILTRFRRQLKRLHGMILVTGPTGSGKTTTLYGALNELNLPGKKLITAEDPVEYRLPRVNQVQVNSKIGLSFSSILRTVLRQDPDVILVGEMRDHETVEIGLRSALTGHLVLSTLHTNNAIDSALRMIDMEAPGYLVASAVRAVLAQRLVRRICPECKEPVALAPQQQVWLESCYPQLSQHTFHYGRGCQSCNFSGYRGRIGVFELLEIDMPMMDALRDNNAVLFGQLARNSQSYKPLIESAMELAMAGTTSIDEVLILGESDNVDLVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1U5</accession>
    <name>D0Z1U5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_003509</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303645.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003509"/>
    <dbReference type="EnsemblBacteria" id="EEZ42476">
        <property type="protein sequence ID" value="EEZ42476"/>
        <property type="gene ID" value="VDA_003509"/>
    </dbReference>
    <dbReference type="GeneID" id="57340018"/>
    <dbReference type="eggNOG" id="COG0388">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1650683at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07572">
        <property type="entry name" value="nit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045254">
        <property type="entry name" value="Nit1/2_C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001110">
        <property type="entry name" value="UPF0012_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="SSF56317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01227">
        <property type="entry name" value="UPF0012"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="3">
        <location>
            <begin position="2"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ42476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="273" mass="30562" checksum="BB0FD2B0F86D774E" modified="2010-01-19" version="1">MTKVGIVQMNSGADPEHNLLKLKKKLKGLQLQGAKLIVTPENTVVFGSKEDYHKVAEPLNDGPIQTELAHFAKQLGIWLLIGSMPIRQQDGAVTATALLYDDQGRLHEHYNKLHMFDVEVADQHHSYRESDTFKPGDEIKVVSTPFGNIGMSICYDVRFPQLYTALREQGADIIVVPAAFTRVTGKAHWEVLLRARAIETQCWVIAAAQWGEHNESRETWGHSMVIDPWGQVVVCQQQGTGVITAHVDPQLTKTIRTNMPVVDHARLHLQPLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1Y3</accession>
    <name>D0Z1Y3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Putative NupC nucleoside permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_001973</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299059.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40941">
        <property type="protein sequence ID" value="EEZ40941"/>
        <property type="gene ID" value="VDA_001973"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1972">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="437016at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005337">
        <property type="term" value="F:nucleoside transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008276">
        <property type="entry name" value="C_nuclsd_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011657">
        <property type="entry name" value="CNT_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002668">
        <property type="entry name" value="CNT_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011642">
        <property type="entry name" value="Gate_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10590">
        <property type="entry name" value="PTHR10590"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07670">
        <property type="entry name" value="Gate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07662">
        <property type="entry name" value="Nucleos_tra2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01773">
        <property type="entry name" value="Nucleos_tra2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="73"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="163"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="191"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="248"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="282"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="338"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="381"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleos_tra2_N" evidence="7">
        <location>
            <begin position="5"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="Gate" evidence="9">
        <location>
            <begin position="89"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleos_tra2_C" evidence="8">
        <location>
            <begin position="191"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ40941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="402" mass="42070" checksum="B2252F13FE5F9AFA" modified="2010-01-19" version="1">MIAVLGIFVLILLAWIISTDRKRIPIKMVSLAFLMQVLFALFVLYVPVGKTILQSITHGVTYVTDYGKDGLSFLFGGLATGSIGFVFAVNVLGIIIFFSALISMLYHIGIMQKVVNVCGGALQRVLGTGRAESLSATANIFVGMSEVPLVIKPYLKSMDDSQLFAVMTCGLASVAGSTMVGYAAVGVDLGYLIAAAFMSAPAGLLMAKIIVPPSEQKISADEITAVEIPKATNVVEALADGAMSGLRMAVTIGATLVAFISVIALLNGMLGDIGALFGVKDLSFQLILGYVFSPVALLIGVPWADVITAGSLIGQKVVMNEFVAFIDLMKVKDTMSPHSVAVVTFALCGFANVTTLAILIGGMGSLIPERRPFIAKYGARAVMAGVLANLMSAAIVSIILSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1Y5</accession>
    <name>D0Z1Y5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Molybdopterin molybdenumtransferase</fullName>
            <ecNumber evidence="7">2.10.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_001975</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>adenylyl-molybdopterin + H(+) + molybdate = AMP + H2O + Mo-molybdopterin</text>
            <dbReference type="Rhea" id="RHEA:35047"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:36264"/>
            <dbReference type="ChEBI" id="CHEBI:62727"/>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.10.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 7">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 7">Belongs to the MoeA family.</text>
    </comment>
    <dbReference type="EC" id="2.10.1.1" evidence="7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001975"/>
    <dbReference type="EnsemblBacteria" id="EEZ40943">
        <property type="protein sequence ID" value="EEZ40943"/>
        <property type="gene ID" value="VDA_001975"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0303">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061599">
        <property type="term" value="F:molybdopterin molybdotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032324">
        <property type="term" value="P:molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00887">
        <property type="entry name" value="MoeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.980.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036425">
        <property type="entry name" value="MoaB/Mog-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001453">
        <property type="entry name" value="MoaB/Mog_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008284">
        <property type="entry name" value="MoCF_biosynth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038987">
        <property type="entry name" value="MoeA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005111">
        <property type="entry name" value="MoeA_C_domain_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036688">
        <property type="entry name" value="MoeA_C_domain_IV_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005110">
        <property type="entry name" value="MoeA_linker/N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036135">
        <property type="entry name" value="MoeA_linker/N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10192">
        <property type="entry name" value="PTHR10192"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00994">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03454">
        <property type="entry name" value="MoeA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03453">
        <property type="entry name" value="MoeA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00852">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53218">
        <property type="entry name" value="SSF53218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63867">
        <property type="entry name" value="SSF63867"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63882">
        <property type="entry name" value="SSF63882"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00177">
        <property type="entry name" value="molyb_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01079">
        <property type="entry name" value="MOCF_BIOSYNTHESIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="6 7" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MoCF_biosynth" evidence="8">
        <location>
            <begin position="174"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ40943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="402" mass="43319" checksum="D1F832D793856A3C" modified="2010-01-19" version="1">MPVETALDKILSQVTPLEATKTVALTDAMGYVLAQDVHSPINVPPFANSAMDGYAYRSADLVNANTLTLAGKAFAGVPFAGECQQGQCIRIMTGAELPKGADTVIMQEETTADGETITFHDKPKHGDNVRPIGDDACQGDIVLAKGTRITAREMPLLASLGIAQFEVYVRPIVAFFSTGDELRPVGEPLEAGQIYDSNRYGIRALLEKFGCDVLDLGIIPDCPDQLRAAFTKASTEADVMITSGGVSVGEADFTKDILDEQGQIGFWKIAMKPGKPFAFGTINNAWFCGLPGNPVSAMLTLYQLVQPMLAKLAGHTQYQAPQRLQAIATTGFKKRPGRTDFQRGIYQINTQGQVEVATTGNQGSGAFSSMHLANCFVVLEQDRGRVEAGEQVTIELFNHTMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1Y9</accession>
    <name>D0Z1Y9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001961</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001961"/>
    <dbReference type="EnsemblBacteria" id="EEZ40929">
        <property type="protein sequence ID" value="EEZ40929"/>
        <property type="gene ID" value="VDA_001961"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1289">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006726">
        <property type="entry name" value="PHBA_efflux_AaeB/fusaric-R"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04632">
        <property type="entry name" value="FUSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="160"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="397"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="421"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="444"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="474"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="509"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="740" mass="84245" checksum="042998EBA7FF65C0" modified="2010-01-19" version="1">MSQSDGLTNTNSKVTTSFSLSKWLFPFCMSDKFKFACKVGLSLTLAYLIPMAMGWPQASTAATTVMLIASTGSKRESLAKGSLRVLGTVVGAVLGLSLVGVFAQEQWLYMLSVSVVVSVIFYFRNAYTKDPTLFMLTGVMTLMMSNGGDAEGAFLYGIDRAYMTVFGVVIYTLVGTFLFPTKTEQNLRQLAADLKEKQQAVFVGIIHRQSLTPTQLDEFDDPLPELIKALFTAQSQLDQRYSLISKECSDVSAYKTEWDLALHYYKQITQQLVAVGQSSFDQHVDGEDFIGNYQDVVEEINQLFSQLDDAWAEQQSHYIGSELKVDFEVDALKNAGHFEKGSAITLGFSLKSLHQKLSKLTEVVTCIDSVTERVSFDKPNINNTSRFIWWDAENFKTALKVFVTYWVAAFIWIYLNPPGGYSFVIFSTIYMSLLSFMPVHPVMLLVLFTFGFLFAVPAYIFVLPNLTLGLELGVFIFLYTFIAFYLFNGPVTIFFLMGLFILNIDNTMFYHFGIVMTVMVLFYQVVLMIIFSHYFPFSSKPEHLFLVMRERLYRHIQHYLMSFSALEPNKFQRRKREFHLKILKFTVPKLKLWASKINLKLFPALSSESLIGFAAASEQLVNHLTILNVYEKSLHNNPLVNKARSQYPDDSLAEMATTLAGGKGKELLTAGFEQYQVDYAKGEKSLEHFFQQVDLTSISHQQIAEFYIFVCVKRNIFEAMNQCKDAYVAIDWDHLRQKRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z234</accession>
    <name>D0Z234_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001883</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298872.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40851">
        <property type="protein sequence ID" value="EEZ40851"/>
        <property type="gene ID" value="VDA_001883"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5032G6N">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="83" mass="9071" checksum="8AD3E362D8571908" modified="2010-01-19" version="1">MQNKDVAALIKMSTFAAVLCAILLVMGNVGLTSSLPVFVMNHVNIIHVGFYLVFNAMFIGLLGLMVFNRQKAVRKQAMQKATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z274</accession>
    <name>D0Z274_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Na(+)-linked D-alanine glycine permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_001919</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell inner membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40887">
        <property type="protein sequence ID" value="EEZ40887"/>
        <property type="gene ID" value="VDA_001919"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1115">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015655">
        <property type="term" value="F:alanine:sodium symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001463">
        <property type="entry name" value="Na/Ala_symport"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30330">
        <property type="entry name" value="PTHR30330"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01235">
        <property type="entry name" value="Na_Ala_symp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00175">
        <property type="entry name" value="NAALASMPORT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00835">
        <property type="entry name" value="agcS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00873">
        <property type="entry name" value="NA_ALANINE_SYMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0769">Symport</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="234"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="277"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="320"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="348"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ40887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="415" mass="44370" checksum="43DBCDFC503A2CB4" modified="2010-01-19" version="1">MAARVGTGNMAGVAVALTVGGPGAIFWMWLIALFGMATAFIESTLAQVYKVKDVDGQYRGGPAYYMEKGLGQRWMGTLFSIFLIIAFGLVFNAVQANTITDALNHSFGVNKIVLGIVIVAFSAFFIMGGLRRVAQASTSIVPVMAIGYLLIAIVIVAMNISELPAVLALIVKSAFGWQEAAVGGVAYTIAQAMQSGIARGLFSNEAGMGSAANVAASATPNPNHPASQGFVQMLGVFTDTIIICTASAAMIMLSGVMDQPDHATGISLLQQALSNELGGWTTYFMVAAIILFCFSSIIANYTYAETNIMFLNGNTKKGLFVFRLCVLAMVMFGSVASLPVVWNLADASMGLMAMTNIIALVFLSKLAIKVIKDYEHQLKAGKIPEFDRTKFPELDDLDGAWHPEEMKLEEAQFKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2A1</accession>
    <name>D0Z2A1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">4-hydroxybutyrate CoA-transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000552</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the acetyl-CoA hydrolase/transferase family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304701.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000552"/>
    <dbReference type="EnsemblBacteria" id="EEZ39532">
        <property type="protein sequence ID" value="EEZ39532"/>
        <property type="gene ID" value="VDA_000552"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0427">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="319106at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008775">
        <property type="term" value="F:acetate CoA-transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003986">
        <property type="term" value="F:acetyl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006083">
        <property type="term" value="P:acetate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019679">
        <property type="term" value="P:propionate metabolic process, methylcitrate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1080.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026888">
        <property type="entry name" value="AcetylCoA_hyd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038460">
        <property type="entry name" value="AcetylCoA_hyd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003702">
        <property type="entry name" value="ActCoA_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13336">
        <property type="entry name" value="AcetylCoA_hyd_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02550">
        <property type="entry name" value="AcetylCoA_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AcetylCoA_hyd_C" evidence="2">
        <location>
            <begin position="272"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="435" mass="46785" checksum="49D04C725CBA811F" modified="2010-01-19" version="1">MNVYNNCDNKIISLEDAANKIKSGDNVWAGGYLSVPVYFLQELSKNASELEGTTLYAGLLTYPYEFLKPEYLGHLNYNSLFMGPLEKKFQHGGNAKIVPYHLSNADEVLKQANCNVSVIEVTPPNAAGYVSLGACGGVGNKYGLESSELVIGIINEYQPFIANEDNLIHVDEFDFLAIGNHPIAGPKPEQPGQIEKNIADHVLPLIPNGSTIQIGIGTISNALGMGLVNHKDLGIHTEMFTESMMELCKLGVINGSRKNYKPNKIVAAFAAGSQELIDFVDGNDNIEIGDVCVVNDPVEIAKNDNFVSINTCIMVDLTGQVASEGIGHQQISGSGGQVDFVRGARMSNNGLSIIALASTHTDKKAGTVDSTIKLALPAGTPITTLRNDVQIIVTEYGYADLRGLTTNARAQELIKIAHPDFRNELIEQAKAVGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2C3</accession>
    <name>D0Z2C3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Beta-hexosaminidase</fullName>
            <ecNumber evidence="9">3.2.1.52</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Beta-N-acetylhexosaminidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">N-acetyl-beta-glucosaminidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">nagZ</name>
        <name evidence="11" type="ORF">VDA_000574</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides.</text>
            <dbReference type="EC" id="3.2.1.52"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="9">Cell wall biogenesis; peptidoglycan recycling.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.52" evidence="9"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000574"/>
    <dbReference type="EnsemblBacteria" id="EEZ39554">
        <property type="protein sequence ID" value="EEZ39554"/>
        <property type="gene ID" value="VDA_000574"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1472">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00544"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004563">
        <property type="term" value="F:beta-N-acetylhexosaminidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102148">
        <property type="term" value="F:N-acetyl-beta-D-galactosaminidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009254">
        <property type="term" value="P:peptidoglycan turnover"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00364">
        <property type="entry name" value="NagZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022956">
        <property type="entry name" value="Beta_hexosaminidase_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019800">
        <property type="entry name" value="Glyco_hydro_3_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00775">
        <property type="entry name" value="GLYCOSYL_HYDROL_F3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 9" id="KW-0132">Cell division</keyword>
    <keyword evidence="4 9" id="KW-0133">Cell shape</keyword>
    <keyword evidence="8 9" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="1 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9 11" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 9 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 9" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro_3" evidence="10">
        <location>
            <begin position="8"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="156"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="9">
        <location>
            <position position="169"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9">
        <location>
            <position position="239"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="9">
        <location>
            <position position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ39554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="330" mass="36498" checksum="84529133FFEB2196" modified="2010-01-19" version="1">MLDVSGFELDAEEREIIQHPTVGGIIFFARNYHDRKQLRALVKDIRQTAKKPLLIAVDQEGGRVQRFRDEFTALPPARAFAQSPNGLDLAKQGGWLMAAELLAMDIDLSLAPVLDLGFDCKAIGDRAFSNDPAEIALYAGEFIQGMKQAGMAATGKHFPGHGGVIADSHLETPYDSRDNIKQHDMQVFQTLINKGLLDAMMPAHVVFDAYDSQPASGSEYWLKQVLRQDLGFNGVIFSDDLNMKGADVLGSYSERAVASMNAGCDMVMLCNNRQGAIEALDGLPQIQVPSLEALLKRPTGEYSDLVQTRTWIETSRNIARLTQEWQERQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2D7</accession>
    <name>D0Z2D7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FGE-sulfatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000588</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304785.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000588"/>
    <dbReference type="EnsemblBacteria" id="EEZ39568">
        <property type="protein sequence ID" value="EEZ39568"/>
        <property type="gene ID" value="VDA_000588"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1262">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005532">
        <property type="entry name" value="SUMF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042095">
        <property type="entry name" value="SUMF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03781">
        <property type="entry name" value="FGE-sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="SSF56436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FGE-sulfatase" evidence="2">
        <location>
            <begin position="65"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="286"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="339" mass="38716" checksum="B66D9ABC36D4EFC3" modified="2010-01-19" version="1">MKVNSILLIIISANLVACNDSENTVSSEIISKQEITRIDTNINKLYPNADSKLKQHILNVAVESLESMVFIKGGTFMMGDFKAPCSPLNIKRMDWNPEASCNTALSMTRTGANYQHKVTLSNYSLSDHETTYYETDAFNRSENKPVANQDSRYDKEFPIQDEQLKNRPSSTKSWQEAKDYCLWLGKLTNYPIDLPTEAQWEYAARNRGKNIYFATNNGYAQEIGSRYVNNDGSIHEYTKEQGNYGYFGDIKRWPPNPLGLYDMAGNSREWVNNWYSKDYYKVSPELNPQGPETGTEKVIRGWGGNMPLTTTRSHEKPTDSRYISQRGFRCAVQSPTSIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2F7</accession>
    <name>D0Z2F7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cyclopropane-fatty-acyl-phospholipid synthase</fullName>
            <ecNumber evidence="3">2.1.1.79</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000608</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CFA/CMAS family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.79" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304854.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000608"/>
    <dbReference type="EnsemblBacteria" id="EEZ39588">
        <property type="protein sequence ID" value="EEZ39588"/>
        <property type="gene ID" value="VDA_000608"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2230">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1518440at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008825">
        <property type="term" value="F:cyclopropane-fatty-acyl-phospholipid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003333">
        <property type="entry name" value="Mycolic_cyclopropane_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003085">
        <property type="entry name" value="CMAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="active site" evidence="2">
        <location>
            <position position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR003085-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="416" mass="47772" checksum="B5BAEF4A29C0E67E" modified="2010-01-19" version="1">MLKEPATIVKSLDKPLTSSISFQISRKVVMALLSQLSHAGLTVTEPNGEQLFFGDKSSDLQAQLTIHNQSFYKRLLQGGSIAAGEAYIDHWWESPNVTDVIRVLARNLATLDKIEAKTSWITQLSTKLSHKLRRNNQDNAKQNISAHYDRGNDLYSAFLDRNMLYSAAIYQSELDDLYHAQINKMDRLCQQLALTPDDHLLEIGTGWGGMAIYAAQYYGCKVTTTTISKEQYAWAQQRVDALGLNDQITLLLEDYRDLTGEYDKIVSIEMIEAVGREYLDMYIEKCQSLLKPGGRFAIQAITIADQRYDSYSKNVDFIQKHIFPGGFLPSVTVLLKTMTEKSDFVVRDMFDMGLDYARTLNDWHRNFNQNIELITLRGYDERFVRMWRYYFCYCEGGFLEKTISAIQLVAERPKYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2H6</accession>
    <name>D0Z2H6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000627</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304909.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000627"/>
    <dbReference type="EnsemblBacteria" id="EEZ39607">
        <property type="protein sequence ID" value="EEZ39607"/>
        <property type="gene ID" value="VDA_000627"/>
    </dbReference>
    <dbReference type="GeneID" id="57342884"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1661500at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="308" mass="35337" checksum="E66881D7A707C335" modified="2010-01-19" version="1">MLENLHQMVILATISHEQNFTRAADRLGISKSQVSKQIRLLEERLGCQLVQRSTRTVVLTEIGLQYAEYGQQLLDTVNEAEAMVAGYRNEVKGVLRIGIAQSFGNHQITPALAEFQQLHPELELEISLFDHRPNLLEEGFDCWIAIHEHPPEGMVARRLANCHFMVVASPEYIAQHGKPETPGDLRRHNCITYQSRERKYVNWEFTRDGIHQSIRARGTYRIDNAPAVLDATVSGLGIAYLSTYLLTDEIEKGKLIQLLPEWKADLELPIYAVYPRRKYLAPKVRSFIDFMSERMAKPPYRDHSPFLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2J4</accession>
    <name>D0Z2J4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DamX-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000645</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304950.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000645"/>
    <dbReference type="EnsemblBacteria" id="EEZ39625">
        <property type="protein sequence ID" value="EEZ39625"/>
        <property type="gene ID" value="VDA_000645"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3266">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1213917at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042834">
        <property type="term" value="F:peptidoglycan binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007730">
        <property type="entry name" value="SPOR-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036680">
        <property type="entry name" value="SPOR-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05036">
        <property type="entry name" value="SPOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110997">
        <property type="entry name" value="SSF110997"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51724">
        <property type="entry name" value="SPOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018844" evidence="1">
        <location>
            <begin position="24"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="SPOR" evidence="2">
        <location>
            <begin position="101"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="195" mass="21160" checksum="97D6B42FDABBDDF0" modified="2010-01-19" version="1">MKKIALVILASLLTGCVTSPQHSAPVQALNTPPTPEVKPQPQTVVVEPAQFSADGLGFNEESLTGKPVEAPNHVKEVVKLSPSVTEPEVEPTTKPTYQYSELNKTAYAIQLVASGSKDQLASYAKQLPKGEALWISKTDRNGQPWYALLYGQYDSRDAAHEAIVTLPLTVQQNGAFIKNLQSLKESKNTQVSSFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2P3</accession>
    <name>D0Z2P3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Sialidase</fullName>
            <ecNumber evidence="5">3.2.1.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_000694</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 33 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.18" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305077.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000694"/>
    <dbReference type="EnsemblBacteria" id="EEZ39674">
        <property type="protein sequence ID" value="EEZ39674"/>
        <property type="gene ID" value="VDA_000694"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4409">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="114817at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052794">
        <property type="term" value="F:exo-alpha-(2-&gt;3)-sialidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052795">
        <property type="term" value="F:exo-alpha-(2-&gt;6)-sialidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052796">
        <property type="term" value="F:exo-alpha-(2-&gt;8)-sialidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033691">
        <property type="term" value="F:sialic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011040">
        <property type="entry name" value="Sialidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026856">
        <property type="entry name" value="Sialidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036278">
        <property type="entry name" value="Sialidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015344">
        <property type="entry name" value="VCNA_lectin-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10628">
        <property type="entry name" value="PTHR10628"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13088">
        <property type="entry name" value="BNR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09264">
        <property type="entry name" value="Sial-lect-inser"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50939">
        <property type="entry name" value="SSF50939"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005669802" evidence="2">
        <location>
            <begin position="24"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="domain" description="Sial-lect-inser" evidence="3">
        <location>
            <begin position="65"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="Sial-lect-inser" evidence="3">
        <location>
            <begin position="345"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="domain" description="Sialidase" evidence="4">
        <location>
            <begin position="554"/>
            <end position="746"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="775" mass="85811" checksum="49D081B557506A0C" modified="2010-01-19" version="1">MRVFKKRLLTGCILSFLSAPLAAHVYQFIPSDNPTNDEPIEQGWNNYLSNSGYGEAVVNQGVDEWYVNGNDGRANWTITPTTELNNQATRYGWTLSTEMRVVSGGYITNYYANGQHRFLPIISLQNGNLVAEFEGRSGATILASGDDVHGYHKYDIVFHPGPNPTASFFFDGVLIKSDWQGHPSSQNMIAWGNGSSSQAGEAYYRSITFTISGDPVFSTPDRIPSLVTSSQTPGTVAIFAEKRMGGGDPGAVTNTNDIITRISKDYGRTWGPEVNLTEQINLNDEYDFSDPRPIYLPQQDTITVSYVRWPTDAAQNGDKIKPWMASGVFYSTYDVANDTWSAPINVSSHVKEKTLQIVGWSGSEFYSKSLDEISSQNSWSLQSKLKIYNGKDNDLVVANGTKQYKISFAVNENGLVAYLDDQNSAKLIRTTIQNIAGFINVAMDFDPVTQTAQLTIDDAVVGTLSGIPSADKHILFGQTNAAHDGRLHIANINLNVNGQRVIDYDAETLTDINPNEMNNTPESQGWSKHKSGRAYSFYGVASVNPGPGHGIELKHQTEVTGNNNGRIIYPAITLDKYFLNVASVFSDDQGVTWDMASHLPVPYRWLPNRLETLEPSETDIVELNNGDILLTARLDFNQTVNNINYGPRHQFISHDGGMTWHMPENYGYQQFSNLSKNTVDASITRFTESDGSNYLLFTNPIGDLANNSGRENLGLWMSFDEGASWQGPIQLVNGGSAYSDIYQLDNENAMVIVEDNSRKIRVLTVPVTKIKQLLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2S5</accession>
    <name>D0Z2S5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000726</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000726"/>
    <dbReference type="EnsemblBacteria" id="EEZ39706">
        <property type="protein sequence ID" value="EEZ39706"/>
        <property type="gene ID" value="VDA_000726"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014991">
        <property type="entry name" value="DUF1840"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08895">
        <property type="entry name" value="DUF1840"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="57" mass="6602" checksum="3BAACA297E9874C0" modified="2010-01-19" version="1">MNATVEATEKEQKLALSEDEENDEEESFVPFANRARPLIDMLETCVKEKCPLMWDKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2W8</accession>
    <name>D0Z2W8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Iron-sulfur cluster assembly protein SufD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000769</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305293.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000769"/>
    <dbReference type="EnsemblBacteria" id="EEZ39749">
        <property type="protein sequence ID" value="EEZ39749"/>
        <property type="gene ID" value="VDA_000769"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0719">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="422804at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000825">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037284">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011542">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43575">
        <property type="entry name" value="PTHR43575"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01458">
        <property type="entry name" value="SUFBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101960">
        <property type="entry name" value="SSF101960"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01981">
        <property type="entry name" value="sufD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="423" mass="47673" checksum="44C9F2660A2412CC" modified="2010-01-19" version="1">MAGSLENKSASTLLNWQALVPDALDQQKHWKKVLELGLPTRCDEDWKFTPFNFLYELPWHDRVPLVQRRIPKDLSYLGSEDVYRMVFINGCWQKELSDSVCGVDISVLKGDDISTESLAVDPLDNEIVVELTEALKTQMVKFTVAPKVILDKPLCIIHYIDSFDGAVCAMRHHYQLGRLSQVKIIEHHVNLSEVSHKGVVFSNTSIEAQDGAQGEYIKIVEQGNEQLHLAHNHIVTNRDANVTSSAYLLSGKWIRHKTSSELGGENGVVEMNSLSLPARDQCFDSRTYLNHSVSHCRSHQLHKMVAVDDGKGVFDGLIYVSPGALKTDGQMDNHNLLIGDKAQINSQPKLEIYADDVKCSHGATTGQLDQEQIFYLQARGIKKELAERMIIKAFAKEVCDLVSFEPIRRYLLDHVEKKLEQSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2Y3</accession>
    <name>D0Z2Y3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glucose-1-phosphate adenylyltransferase</fullName>
            <ecNumber evidence="9">2.7.7.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">ADP-glucose pyrophosphorylase</fullName>
            <shortName evidence="9">ADPGlc PPase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">ADP-glucose synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">glgC</name>
        <name evidence="12" type="ORF">VDA_000784</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>alpha-D-glucose 1-phosphate + ATP + H(+) = ADP-alpha-D-glucose + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:12120"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57498"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="EC" id="2.7.7.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="9 10">Glycan biosynthesis; glycogen biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.27" evidence="9"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305340.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000784"/>
    <dbReference type="EnsemblBacteria" id="EEZ39764">
        <property type="protein sequence ID" value="EEZ39764"/>
        <property type="gene ID" value="VDA_000784"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0448">
        <property type="taxonomic scope" value="Bacteria"/>
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        <property type="component" value="Unassembled WGS sequence"/>
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        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:glucose-1-phosphate adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005978">
        <property type="term" value="P:glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00624">
        <property type="entry name" value="GlgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011831">
        <property type="entry name" value="ADP-Glc_PPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005836">
        <property type="entry name" value="ADP_Glu_pyroP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023049">
        <property type="entry name" value="GlgC_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43523">
        <property type="entry name" value="PTHR43523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02091">
        <property type="entry name" value="glgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00808">
        <property type="entry name" value="ADP_GLC_PYROPHOSPH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ADP_GLC_PYROPHOSPH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7 9 10" id="KW-0320">Glycogen biosynthesis</keyword>
    <keyword evidence="2 9" id="KW-0321">Glycogen metabolism</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 9 12" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transferase" evidence="11">
        <location>
            <begin position="6"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Alpha-D-glucose 1-phosphate binding" evidence="9">
        <location>
            <begin position="176"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>alpha-D-glucose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>alpha-D-glucose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>alpha-D-glucose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
        </ligand>
    </feature>
    <feature type="site" description="Could play a key role in the communication between the regulatory and the substrate sites" evidence="9">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <feature type="site" description="Could play a key role in the communication between the regulatory and the substrate sites" evidence="9">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023056"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="HAMAP-Rule" id="MF_00624"/>
        </source>
    </evidence>
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            <dbReference type="RuleBase" id="RU003742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EEZ39764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="405" mass="45072" checksum="C3558F70B137F00C" modified="2010-01-19" version="1">MAGVLGMILAGGEGSRLRPLTDTRTKPAVPFGGSYRLIDFALNNFVNADLLKIYVLTQFKSQSLYLHMKKGWTISGITDRFIDPVPAQMRMGKRWYDGTADAIYQNIRFIEMEDPDQVCIFGSDHIYKMDVKQMLNFHKEKQAELTVSALRMPLSQASSFGVIEVDEHGCMIGFEEKPANPKSIPGDPEHALVSMGNYVFETATLLTELEADAIDDSSSHDFGKDIIPKLFPQGKVFVYDFNNNIIPGEKSTGYWRDVGTIEAYWQAHMDLLAEEPAFSLYNSKWQLHTYYPPLPPATIIDSKECKVDINNCMISAGSYIHGATVHKSVLGFKTNIDTCSIITESVILGDVKIGANCSIRRAIIDKNVEIAPGTIIGENLEEDRKKYHVSDEGIVVIPKGAKIGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z303</accession>
    <name>D0Z303_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative glutathione S-transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000804</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305396.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000804"/>
    <dbReference type="EnsemblBacteria" id="EEZ39784">
        <property type="protein sequence ID" value="EEZ39784"/>
        <property type="gene ID" value="VDA_000804"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0625">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1997747at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13417">
        <property type="entry name" value="GST_N_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="SSF47616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="2"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="2">
        <location>
            <begin position="87"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="218" mass="25773" checksum="73EA78C3DCC9438C" modified="2010-01-19" version="1">MSTPILYSLRQCPYAIRARLGLYFAQIQVELREVDMKNKPRDMLKISAKGTVPLLVIPNGDYLDESLEIMVWALNQHDPNHLLLEDDPHHFADMLSLIAKFDSKFIPALERYKAAARYHDLDIELRRHQCEILLKDLEQRLCKTPFIMGQHPSLVDYALLPFIRQFSKVERHWYLESPYPLIRQWLTVHFQNPAFSLVMKQYDKWSDSHDFHSVILID</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z331</accession>
    <name>D0Z331_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Anaerobic dimethyl sulfoxide reductase chain A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_000832</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305473.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000832"/>
    <dbReference type="EnsemblBacteria" id="EEZ39812">
        <property type="protein sequence ID" value="EEZ39812"/>
        <property type="gene ID" value="VDA_000832"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0243">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="88184at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009389">
        <property type="term" value="F:dimethyl sulfoxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030151">
        <property type="term" value="F:molybdenum ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043546">
        <property type="term" value="F:molybdopterin cofactor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011888">
        <property type="entry name" value="Anaer_DMSO_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006657">
        <property type="entry name" value="MoPterin_dinucl-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006656">
        <property type="entry name" value="Mopterin_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006963">
        <property type="entry name" value="Mopterin_OxRdtase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04879">
        <property type="entry name" value="Molybdop_Fe4S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00384">
        <property type="entry name" value="Molybdopterin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01568">
        <property type="entry name" value="Molydop_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="SSF50692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02166">
        <property type="entry name" value="dmsA_ynfE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51669">
        <property type="entry name" value="4FE4S_MOW_BIS_MGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0574">Periplasm</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="domain" description="4Fe-4S Mo/W bis-MGD-type" evidence="9">
        <location>
            <begin position="52"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ39812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="805" mass="90727" checksum="0B5357AA6A3F3933" modified="2010-01-19" version="1">MFKNRKEKNKTNKFSRRSFLKLSAYLGTGAFISTHPLNAIASAVINTHVGEITKWHNCWAHCHSSCLLKIVTENGKIKRIETDDQGNDEFGQHQVRACLRGRSLHKRTFAPDRLKYPMKRIGKRGEGKFKRISWDEALTEVHSQLSRIIKQHGNQAIFSRIGYGKPNGPYHYVPRFLNLIGGFLSPAGNYSSHQIDTAALYTYGHKSYTMGSAPTELSRSDLIIYFGNNPANTRMSGGSDTYHYQVSKAKSSARTIIIDPQYTDTACGREDQWIAIRPGTDALLIEALAWVLITENFVDESFVKKYCYGYDSEPAIPERNIPALDASYGYKSYILGLGKDGLAKTPEYAAPICGIPSQQIYKLARELGHAKAPFIAQGWGPQRHAAGEQTARAIFMLPILLGKIGLPGTNNGGSDFLFHKTDIVTMPTGTNPIKAKVPCFKWSEAVYRGNSMTALTDGIVGVDKLDTNIKCVFMYQGNWLLNQHSDCNAMSKMLANEDLLEFIFVMDNHMTASAKFADILLPDITWLENSRIVAFSTHVTKTEHVLDPMYECRHPYDVFADLSEKFGVKEQYMEGRTWDDWQRYLYEQSRVNHPNFPSYDVLSKYKTVRLPFDPDADRYVLKEYRLDPQSNPLPTESGKIQIFSHKLAEFSRTWQLPIGDTITPLPQYIGTWESYTDVETKRTYPLQLIGFKSKGRPHSTFHNVPWLREVVEDALIMNPIDAKERQLVQGQLIHIYNDRGTIQVPVKITPRIMPGVVALGEGAWYQPDSKGIDVGGCINTITRLKPTALAKANPQGTNLVEVKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z348</accession>
    <name>D0Z348_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="12">ATP-dependent RNA helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">VDA_000849</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the DEAD box helicase family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305522.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000849"/>
    <dbReference type="EnsemblBacteria" id="EEZ39829">
        <property type="protein sequence ID" value="EEZ39829"/>
        <property type="gene ID" value="VDA_000849"/>
    </dbReference>
    <dbReference type="GeneID" id="57343097"/>
    <dbReference type="eggNOG" id="COG0513">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="643629at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7 12" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Q_MOTIF" evidence="11">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="32"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="234"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="388"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="6">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ39829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="430" mass="48326" checksum="0FC13AEB41AB7AC6" modified="2010-01-19" version="1">MSFSAQGFSQELVKALTEIGYEKLTPIQKQAIPQLRRGHDVLANAQTGTGKTAAFSLPIIQKMLDNPQPRSRMNVRALILAPTRELVEQIANNIKDYTRYTDLTTVAVFGGRKIATQEKKLESGCDILVATPGRLLEHLELQNVLLSNIEFLVFDEADRMLDMGFISAIRTILSNVNSTPQIMLFSATFSSQMNKLAGELLNKPKRISVTPENSTAETVAHVVYPVDEERKREMLSELIGKKNWQQVLVFVNYKETANQLVEELELDGIKAVLCHGDKAQGARRRALKEFKEGKARVMVATEVAARGLDIQGLPHVVNYDMPFLAEDYVHRIGRTGRAGQQGHAVSFVSREEELTLIQIERLIGQRIHRVQLVGYEPKSRDALLEKMNTKASFRDRRGRTNNPNEDKSSAERRARLRKAIQNKAKLGSIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z350</accession>
    <name>D0Z350_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000851</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305527.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000851"/>
    <dbReference type="EnsemblBacteria" id="EEZ39831">
        <property type="protein sequence ID" value="EEZ39831"/>
        <property type="gene ID" value="VDA_000851"/>
    </dbReference>
    <dbReference type="GeneID" id="57343099"/>
    <dbReference type="eggNOG" id="COG4977">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1459004at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020449">
        <property type="entry name" value="Tscrpt_reg_HTH_AraC-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00032">
        <property type="entry name" value="HTHARAC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018865" evidence="2">
        <location>
            <begin position="20"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="HTH araC/xylS-type" evidence="3">
        <location>
            <begin position="219"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="327" mass="37189" checksum="0B1ED5DB862BE18E" modified="2010-01-19" version="1">MRVGFVLYHRALITGISLAAEMLSSASTLRERRLQKESPFSLKIVAPTLTSPKLTAGIRIEPDVTFNDEEQFDLVILPPMWGNPLSAIHNTPGLTEWLIKQYQNGSQLMATGTSVVWLAETGLLNDQVATTHWYFYDKFSQRYPKIKLNRQASITAANGLYCTGSINSQTEMILYIIEKYYGQKIATTIETHYGHEISKSGQQPFYQIGGQAQFDESIALAQEWMKRHLSESITATDIANACRLPLRTFNRRFKDQVGQTPHQYLQGIRMDTAQQLLRDFGLSIQDVAEHVGYQDAYHFSTRFKQVFKVTPSQYRNMVKAKIYNVSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z388</accession>
    <name>D0Z388_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein-export membrane protein SecF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">secF</name>
        <name evidence="10" type="ORF">VDA_000889</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the SecD/SecF family. SecF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000889"/>
    <dbReference type="EnsemblBacteria" id="EEZ39869">
        <property type="protein sequence ID" value="EEZ39869"/>
        <property type="gene ID" value="VDA_000889"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0341">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015450">
        <property type="term" value="F:protein-transporting ATPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043952">
        <property type="term" value="P:protein transport by the Sec complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01464_B">
        <property type="entry name" value="SecF_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022813">
        <property type="entry name" value="SecD/SecF_arch_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022645">
        <property type="entry name" value="SecD/SecF_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022646">
        <property type="entry name" value="SecD/SecF_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005665">
        <property type="entry name" value="SecF_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30081">
        <property type="entry name" value="PTHR30081"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07549">
        <property type="entry name" value="Sec_GG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02355">
        <property type="entry name" value="SecD_SecF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01755">
        <property type="entry name" value="SECFTRNLCASE"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00916">
        <property type="entry name" value="2A0604s01"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00966">
        <property type="entry name" value="3a0501s07"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="109"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="138"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="162"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ39869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="281" mass="30394" checksum="0C05BA14CC69C020" modified="2010-01-19" version="1">MVISISFVCLKGLNWGLDFTGGVVSEVQLADNKVTSSELRPLLDAGFNQDVVVIAADEPGRWVLRYATPAKGVQYPALNEVLAPLKTDVQVLNTSIVGPQVGKELADQGGLALLLSLLCIMGYLSYRFEWRLASGSLLALLHDVVLVLGFFAATQMEFNLTVLAAVLAILGYSLNDSIIIADRIRELLIAKPKQTLEETNNEAIVATFSRTMVTSGTTLMTVGSLWLLGGASLEGFSIAMFIGILTGTWSSISVGTVLPEYLGLKPEHYMPKPEPKEEEYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3A9</accession>
    <name>D0Z3A9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000910</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39890">
        <property type="protein sequence ID" value="EEZ39890"/>
        <property type="gene ID" value="VDA_000910"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5032RH3">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="224" mass="24053" checksum="A7EFA06912C08005" modified="2010-01-19" version="1">MGGRKSQEVPETTAQKTQAEVANKQWDLYENELKGFENKFIQRVDNFNSSSKMEKTKQTAGLSYASSFGHARKQLDQSMTANGVDPSSQKFQNAQANLSDDQGLELSDTVNRAQSSEQDKYLAGLQDVAAMGMGQKSDALGSIGDVANASLRKATSDAYDSFNRRAANNQLIGTVTGAGVSAGLRQLPSFKSASLDGASVDGISTTKRLNSYNNRFNPSGTMIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3B6</accession>
    <name>D0Z3B6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000917</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305714.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000917"/>
    <dbReference type="EnsemblBacteria" id="EEZ39897">
        <property type="protein sequence ID" value="EEZ39897"/>
        <property type="gene ID" value="VDA_000917"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031YN0">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1911885at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="142" mass="16129" checksum="80D8DE648C5BE419" modified="2010-01-19" version="1">MSKISIAYIGDKPFKKDTITGSLLVFPQYQPIDVEAPTAFMLLQYPKVWVRSEDIEVTKEQKQLAADERAKLLEDEQKEQEALEFAKSMVVTVAGENLDLAKLPSVKLATLIEANDWELEPKGAQESVDEFRTRVRDFIRGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3D6</accession>
    <name>D0Z3D6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">YqaJ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000937</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305774.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000937"/>
    <dbReference type="EnsemblBacteria" id="EEZ39917">
        <property type="protein sequence ID" value="EEZ39917"/>
        <property type="gene ID" value="VDA_000937"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3206">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1563636at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011604">
        <property type="entry name" value="PDDEXK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017482">
        <property type="entry name" value="Phage_endonuclease_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019080">
        <property type="entry name" value="YqaJ_viral_recombinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09588">
        <property type="entry name" value="YqaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03033">
        <property type="entry name" value="phage_rel_nuc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YqaJ" evidence="1">
        <location>
            <begin position="13"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="535" mass="59924" checksum="9B642B1577FFDDBD" modified="2010-01-19" version="1">MKIVNVKQGTQAWLELRKSKFTASEAPAAMGESKYQSRDALLKMKATGETPEVNSYQENIFAKGHAAEEAARPLVENIIGDELFPATAISDEYDWMLASFDGITIMEDVVFEHKLFNHNLHEHVLNNDLEPQYYWQLEQQLLVSGAKKAIFVCSDGTSDNFASCDYYSQPERREQLIAGWLQFQKDLASYNSKPEAEKVEAEPMRDLPAICYKMDGLTLSSNLDAFKQAATELVEKSKLPIETDQDFANAEQMVKTFKTAEDKIKALSEQVLGEVQSIDSFVKDLKFIGEQIRQARLATDKQVKNRKDEIRKKILATANKKIQQHTLQLEQQIKASLPAPTISVLNAMKGKKTIQSLQEAADTAVSQVIVELDLQANKARKNLICLNQNAKYKFLFSDWNSLCFKENDDFDALITSRIAKHKEAEKQRLEQERLGIQQEESQPIVHKTLGAESTEPSPSNSSFKLNAETTAALSGKFVVANNIASKTLMVQLTAKEANYLRQRDAILTALENAGVDNWVGYSNAIATLKSAQNVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3F9</accession>
    <name>D0Z3F9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Galactose-1-phosphate uridylyltransferase</fullName>
            <ecNumber evidence="13">2.7.7.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">VDA_000960</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 12 13">
            <text>alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose</text>
            <dbReference type="Rhea" id="RHEA:13989"/>
            <dbReference type="ChEBI" id="CHEBI:58336"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="ChEBI" id="CHEBI:66914"/>
            <dbReference type="EC" id="2.7.7.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="11">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 13">Carbohydrate metabolism; galactose metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.12" evidence="13"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305838.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000960"/>
    <dbReference type="EnsemblBacteria" id="EEZ39940">
        <property type="protein sequence ID" value="EEZ39940"/>
        <property type="gene ID" value="VDA_000960"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1085">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1064872at2"/>
    <dbReference type="UniPathway" id="UPA00214"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008108">
        <property type="term" value="F:UDP-glucose:hexose-1-phosphate uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033499">
        <property type="term" value="P:galactose catabolic process via UDP-galactose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00608">
        <property type="entry name" value="GalT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001937">
        <property type="entry name" value="GalP_UDPtransf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019779">
        <property type="entry name" value="GalP_UDPtransf1_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005850">
        <property type="entry name" value="GalP_Utransf_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005849">
        <property type="entry name" value="GalP_Utransf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11943">
        <property type="entry name" value="PTHR11943"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02744">
        <property type="entry name" value="GalP_UDP_tr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01087">
        <property type="entry name" value="GalP_UDP_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000808">
        <property type="entry name" value="GalT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="SSF54197"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00209">
        <property type="entry name" value="galT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00117">
        <property type="entry name" value="GAL_P_UDP_TRANSF_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 13" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8 13" id="KW-0299">Galactose metabolism</keyword>
    <keyword evidence="6 11 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 13 16" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 13 16" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="GalP_UDP_transf" evidence="14">
        <location>
            <begin position="6"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="GalP_UDP_tr_C" evidence="15">
        <location>
            <begin position="187"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-UMP-histidine intermediate" evidence="10 12">
        <location>
            <position position="168"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11 12">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000808-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000808-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EEZ39940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="350" mass="40548" checksum="E48AB732550C5804" modified="2010-01-19" version="1">MSNVEFNPVDHPHRRYNPLTGQWILVSPHRAKRPWSGADEKPATEQLPSYDSKCFLCPTNERISGDVNPDYKGTYVFTNDFAALMVDSPDAPKSDNPLFQTQGVRGLSRVICFSPDHSKTLPELPVEKIRGVIDTWNDQIEELGKDYIWVQAFENKGEAMGCSQPHPHGQIWANSFLPNEIERKEHNLKTYYLENGRNLLVDYVQAELKDGSRIVVETEHWVALVPYWAAWPFETMLLPKTHIRRMSELTEGQRDDLALAIKKLTSRYDNLFQCSFPYSMGWHYAPFFEQGTNIDHWQLHALFYPPLLRSATVRKFMVGYEMLAESQRDLTAEQAAQRLRDLSDIHYKEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3H1</accession>
    <name>D0Z3H1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">LemA protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_000972</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the LemA family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000972"/>
    <dbReference type="EnsemblBacteria" id="EEZ39952">
        <property type="protein sequence ID" value="EEZ39952"/>
        <property type="gene ID" value="VDA_000972"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1704">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023353">
        <property type="entry name" value="LemA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007156">
        <property type="entry name" value="MamQ_LemA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34478">
        <property type="entry name" value="PTHR34478"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04011">
        <property type="entry name" value="LemA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140478">
        <property type="entry name" value="SSF140478"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ39952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="158" mass="17969" checksum="DDB7F84F71953623" modified="2010-01-19" version="1">MENNYQRRADLIPNLVATVKGYASHEKETLTVVTEARAKVSSIQITPETLNNPQAFKQFEQAQSQLSSALSRLMMVSERYPDLKANEQFQTLQAQLEGTENRIAIARRDYIESVKAFNTEIRTFPGRLWHSLMYSDLEVKPTFTATTPNADVAPKVEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3P1</accession>
    <name>D0Z3P1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001042</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306063.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001042"/>
    <dbReference type="EnsemblBacteria" id="EEZ40022">
        <property type="protein sequence ID" value="EEZ40022"/>
        <property type="gene ID" value="VDA_001042"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="750230at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="2"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="304" mass="33915" checksum="1D3C5EA14DEFC60C" modified="2010-01-19" version="1">MLDLNWLNTFVTLAKYEHFGKTAIALHMTQPNVSLQIKQLEQVTRVKLIERNPFRLTQAGERLLASAENALMELQICQADLNAINELNQGTLSIAASDIISRLLLIGPFQSFRKEFPGIDLSLFNTTSSQAAELVKSAKADLGFVIAQKESQPLHFTELRQVKWCALGNGLQQWQALAENTEIITMSVEEEILTADEPTLILLGHDTRTRDLIDLALPSLNLPKYRIMEVGSVDAQIDWAEAGFGVAIIPAFSVHSKLDLKTKITPLPDFPTTSLGYIVRQNQVLSRAIKQLLGWVDQEIQKSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3V0</accession>
    <name>D0Z3V0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">ATP synthase subunit alpha</fullName>
            <ecNumber evidence="14">7.1.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">ATP synthase F1 sector subunit alpha</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">F-ATPase subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">atpA</name>
        <name evidence="18" type="ORF">VDA_001103</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 14">Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:57720"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.1.2.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="13">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="14">Cell membrane</location>
            <topology evidence="14">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.</text>
    </comment>
    <dbReference type="EC" id="7.1.2.2" evidence="14"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001103"/>
    <dbReference type="EnsemblBacteria" id="EEZ40081">
        <property type="protein sequence ID" value="EEZ40081"/>
        <property type="gene ID" value="VDA_001103"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0056">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18113">
        <property type="entry name" value="ATP-synt_F1_alpha_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01132">
        <property type="entry name" value="F1_ATPase_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.150.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01346">
        <property type="entry name" value="ATP_synth_alpha_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023366">
        <property type="entry name" value="ATP_synth_asu-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000793">
        <property type="entry name" value="ATP_synth_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038376">
        <property type="entry name" value="ATP_synth_asu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033732">
        <property type="entry name" value="ATP_synth_F1_a"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005294">
        <property type="entry name" value="ATP_synth_F1_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036121">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00306">
        <property type="entry name" value="ATP-synt_ab_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50615">
        <property type="entry name" value="SSF50615"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00962">
        <property type="entry name" value="atpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 14" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="6 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 14" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10 14" id="KW-0139">CF(1)</keyword>
    <keyword evidence="5 14" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="18" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 14" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 14" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 14" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATP-synt_ab_N" evidence="17">
        <location>
            <begin position="9"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-synt_ab" evidence="15">
        <location>
            <begin position="129"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-synt_ab_C" evidence="16">
        <location>
            <begin position="362"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="149"/>
            <end position="156"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Required for activity" evidence="14">
        <location>
            <position position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00026013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF02874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EEZ40081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="493" mass="53192" checksum="611161FAFEAB07E3" modified="2010-01-19" version="1">MATQARNEGTIVSVSDGIITINGLADVMQGEMIELPDNRFALALNLERHSVGAVVMGPYADLAEGMKVKGTGRILEVPVGKGLLGRVVNTLGQPIDGKGPLEHDGFSPVEVIAPGVIDRKSVDQPIQTGYKAVDSMVPIGRGQRELIIGDRQTGKTAMAIDAIINQRDTGIYSIYVAIGQKASTIANVVRKLEENGALQNTIVVVASASEAAALQYLAPYSGCAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLLLKRPPGREAFPGDVFYLHSRLLERAARVNSDYVERFTKGEVKGQTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLQTHLFNAGLRPAVDPGISVSRVGGAAQTKIIKKLSGGIRTALAQYRELAAFAQFSSDLDDATRKQLDHGEKVTELMKQKQYSPMSVALQALAVFSAEKGYLNDVPLAKIGEFEAELIAFAKSAYSELLDRINQTGDYNDEIEASLHELLKAFVQTQSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3V4</accession>
    <name>D0Z3V4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="11 12">ATP synthase subunit a</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">ATP synthase F0 sector subunit a</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">F-ATPase subunit 6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">atpB</name>
        <name evidence="13" type="ORF">VDA_001107</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11 12">Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11 12">Cell membrane</location>
            <topology evidence="11 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11 12">Belongs to the ATPase A chain family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306240.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001107"/>
    <dbReference type="EnsemblBacteria" id="EEZ40085">
        <property type="protein sequence ID" value="EEZ40085"/>
        <property type="gene ID" value="VDA_001107"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0356">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="867266at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045263">
        <property type="term" value="C:proton-transporting ATP synthase complex, coupling factor F(o)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01393">
        <property type="entry name" value="ATP_synth_a_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045082">
        <property type="entry name" value="ATP_syn_F0_a_bact/chloroplast"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000568">
        <property type="entry name" value="ATP_synth_F0_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023011">
        <property type="entry name" value="ATP_synth_F0_asu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035908">
        <property type="entry name" value="F0_ATP_A_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42823">
        <property type="entry name" value="PTHR42823"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00119">
        <property type="entry name" value="ATP-synt_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00123">
        <property type="entry name" value="ATPASEA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81336">
        <property type="entry name" value="SSF81336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01131">
        <property type="entry name" value="ATP_synt_6_or_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00449">
        <property type="entry name" value="ATPASE_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 11 12" id="KW-0138">CF(0)</keyword>
    <keyword evidence="6 11 12" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 11 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="33"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="86"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="132"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="196"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="223"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ40085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="255" mass="29097" checksum="E3F86322FA0A950F" modified="2010-01-19" version="1">MDTVTTAHDYIEHHMTFLTVGKGFWSINLDSMLMVWVLGLLFIGLFRYVVTRGTSGVPGRLQCFVEVTFEFVNNLVKEIFKTDDKLIGPLSLTIFVWVFLMNTIDLLPVDFIPHVMGLLGFGHFRDLPSADVNVPMSMAIGVFILIIGYTFKNKGFVGFIKELTTQPFENPLLYPVNFVLELVTLISKPISLGLRLFGNMYAGEMIFILIALMPWWMQWALSVPWALFHILIVFLQAFIFMVLTIVYLAMAVEEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z449</accession>
    <name>D0Z449_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Urease subunit alpha</fullName>
            <ecNumber evidence="5">3.5.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Urea amidohydrolase subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ureC</name>
        <name evidence="13" type="ORF">VDA_000305</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5 10">
            <text>2 H(+) + H2O + urea = CO2 + 2 NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:20557"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16199"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.1.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5 7 10">
            <name>Ni cation</name>
            <dbReference type="ChEBI" id="CHEBI:25516"/>
        </cofactor>
        <text evidence="5 7 10">Binds 2 nickel ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 5">Nitrogen metabolism; urea degradation; CO(2) and NH(3) from urea (urease route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="6">Carbamylation allows a single lysine to coordinate two nickel ions.</text>
    </comment>
    <comment type="PTM">
        <text evidence="5">Carboxylation allows a single lysine to coordinate two nickel ions.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 11">Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.5" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303993.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000305"/>
    <dbReference type="MEROPS" id="M38.982"/>
    <dbReference type="EnsemblBacteria" id="EEZ39287">
        <property type="protein sequence ID" value="EEZ39287"/>
        <property type="gene ID" value="VDA_000305"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0804">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="157757at2"/>
    <dbReference type="UniPathway" id="UPA00258">
        <property type="reaction ID" value="UER00370"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009039">
        <property type="term" value="F:urease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043419">
        <property type="term" value="P:urea catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00375">
        <property type="entry name" value="Urease_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01953">
        <property type="entry name" value="Urease_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011612">
        <property type="entry name" value="Urease_alpha_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017950">
        <property type="entry name" value="Urease_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005848">
        <property type="entry name" value="Urease_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017951">
        <property type="entry name" value="Urease_asu_c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029754">
        <property type="entry name" value="Urease_Ni-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00449">
        <property type="entry name" value="Urease_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01752">
        <property type="entry name" value="UREASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01792">
        <property type="entry name" value="urease_alph"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01120">
        <property type="entry name" value="UREASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00145">
        <property type="entry name" value="UREASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51368">
        <property type="entry name" value="UREASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5 7" id="KW-0533">Nickel</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Urease" evidence="12">
        <location>
            <begin position="129"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5 8 9">
        <location>
            <position position="320"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="via carbamate group" evidence="5 7">
        <location>
            <position position="217"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 9">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <position position="272"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <position position="360"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-carboxylysine" evidence="5 6">
        <location>
            <position position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR611612-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR611612-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR611612-52"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ39287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="567" mass="61080" checksum="7D016C51D1A91B25" modified="2010-01-19" version="1">MANISRQAYSDMFGPTVGDRVRLADTELLLEVERDFTTYGEEVKFGGGKVIRDGMGQSQVTSEHCVDVLITNALIIDHWGIVKADIGIKDGRISGIGKAGNPDVQPNVDIVIGPGTEVVAGEGKIVTAGGIDTHIHFICPQQAEEGLCSGLTTFIGGGTGPVAGSNATTVTPGVWNMSRMLEAVDDLPINVGLFGKGCVSKPEALREQIEAGAVGLKLHEDWGATPAAINNCMNVADEMDIQVAIHSDTLNEGGFYEETVKAIGDRVIHVFHTEGAGGGHAPDVIKSVGEHNILPASTNPTMPYTINTVDEHLDMLMVCHHLDPSIPEDVAFAESRIRRETIAAEDILHDLGAISVMSSDSQAMGRVGEVITRTWQCANKMKLQRGSLEGDTPFNDNTRIKRYIAKYTINPAIAHGISHEVGSLEVGKLADIVLWDPAFFGVKPALILKCGLVAYAPMGDINAAIPTPQPVHYRPMYACYGKAMYSSSMIFMSQAGIDNGVPEQLNLKSRIGRVHGCRNISKKDMIHNSYTPCIELDSQTYEVKADGIPLTCEPATELPMAQRYFLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z470</accession>
    <name>D0Z470_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidase T2 asparaginase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000326</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304054.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000326"/>
    <dbReference type="EnsemblBacteria" id="EEZ39308">
        <property type="protein sequence ID" value="EEZ39308"/>
        <property type="gene ID" value="VDA_000326"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1446">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="890789at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000246">
        <property type="entry name" value="Peptidase_T2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10188">
        <property type="entry name" value="PTHR10188"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01112">
        <property type="entry name" value="Asparaginase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="193"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="216"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="165"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage; by autolysis" evidence="3">
        <location>
            <begin position="164"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR600246-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR600246-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR600246-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="308" mass="33812" checksum="D9F7D430533ACB0C" modified="2010-01-19" version="1">MILIANSEAYPGIAETARQLQAGEDGLIASIEGIRLVESDPRVRTVGYGSWPNVLGEMELDASVMDGNSLRTGAVGALKGFMHPIDVAYRVMTDLNHEILVGEGAAIFAKEIEAKEGDNLIEDSKRVWWEKLEQSMTEEEKNAFPHIPLAKLSNNATDPERVRDTTVFLASDSEHKITAATSTSGWAWKYPGRLGDSPIIGAGSYADSRYGACACTHTGEMNIRCSTAHAVVLYMKMGMSLDDAVYEAINDLKYLKDGYTEGVTIHAIDNKGNHKVVSLNCPGPIPYWFWQDGMYGPEERFAEVIMTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4D2</accession>
    <name>D0Z4D2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000388</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304227.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000388"/>
    <dbReference type="EnsemblBacteria" id="EEZ39370">
        <property type="protein sequence ID" value="EEZ39370"/>
        <property type="gene ID" value="VDA_000388"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0673">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1465613at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="1">
        <location>
            <begin position="2"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="328" mass="36594" checksum="88DA71E53E38B569" modified="2010-01-19" version="1">MIKLAVVGTNWITDQFVEVALATEQFSLKAVYSRDIQRAQEFGLKYHATHYYDKLEQLADDTEIDAVYIASPNALHAPQAITLMQSGKHVICEKPLGSNYNQVQQMFAAAHSNNVVLFEAFMSPYQPNFQVIKDQLPSLGALRKAQISYCQYSSRYQKYLNGENPNTFNPEFSNGSIVDIGYYCVASAIELFGEPQTIKATAHLLESGVDGSGCVLLGYEEFDVVIMHSKISNSYVPSEFQGEDANLLVDMISTGRGVTKISRQGAQTDLTLVQHSNSMFYEAHAFAQRIQQGKIDPKEQQRSLIVAKVLTEIRRQTGVIFPADNIIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4G1</accession>
    <name>D0Z4G1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Galactose operon repressor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_000417</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304310.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000417"/>
    <dbReference type="EnsemblBacteria" id="EEZ39399">
        <property type="protein sequence ID" value="EEZ39399"/>
        <property type="gene ID" value="VDA_000417"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1796334at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00036">
        <property type="entry name" value="HTHLACI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="2"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="332" mass="36122" checksum="39FAD3BDB4385D7F" modified="2010-01-19" version="1">MATIKDVAKEAGVSVATVSRVINKSPKASQASIDSVTQAMKKLGYRPNAAARALVSQSTNTMGVVVGDVSDPFFGSLIKSIDHVAHENGKHILIGNGYHNAGDERQAIELMIDNRCEAMVVHAKGLTDKELIAYANEVPGMVFINRNIPELSHRCISLDNHRGAYLATEFLIRHGHTKIACIASSHEIEDTDQRLQGYLDALKDNHIELSKRYIECGEPNSDGGEHAMTNLLTKSLDITAIVAYNDYMAAGAMAVLDQNGIDVPEKASIIGFDDGLIARFVSPSLTTIRYPIEMMADRAAQLALALSRGEQPEDETIVFSPTLVRRNSVDKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4G8</accession>
    <name>D0Z4G8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Carboxynorspermidine dehydrogenase putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000426</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304328.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000426"/>
    <dbReference type="EnsemblBacteria" id="EEZ39406">
        <property type="protein sequence ID" value="EEZ39406"/>
        <property type="gene ID" value="VDA_000426"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1748">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1006830at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032095">
        <property type="entry name" value="Sacchrp_dh-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005097">
        <property type="entry name" value="Sacchrp_dh_NADP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16653">
        <property type="entry name" value="Sacchrp_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03435">
        <property type="entry name" value="Sacchrp_dh_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sacchrp_dh_NADP" evidence="1">
        <location>
            <begin position="3"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="Sacchrp_dh_C" evidence="2">
        <location>
            <begin position="149"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="418" mass="46519" checksum="6DAD0B750B283010" modified="2010-01-19" version="1">MAVLQIGAGGVGWVVAHKLAQYNDVFGDITLASRTVAKCDTIIESILRKNNLKDTTKRLTSAAVDADSVEALIALINQVKPDLVVNAGPPWVNVTIMEACVQTKTAYLDTSVATDLCSEGQQVPEAYDPQWAFRERFEQAGITGLLGCGFDPGVVSVFAAYAWKHMFDEIDTIDVMDVNAGNHGRKFATNFDPETNMLEIQGDSFYWEQGEWKRVPCHTRMMEFDFPVVGDQKVYSMAHDEVRSMAEYIPVKKRIEFWMGFGDNYLKYFNVMRDIGLLSPDPVTTVDGVTISPLKVLKAILPEPTSLAKDYTGNTCIGTMVAGQKDGKERKVFIYNICNHKACYEEVESQAISYTTGVPAITAALLYFKGQWNQKGLFNVEQLDPDPYLELMPSIGLSWDVVELDPAQDQTINWLGDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4I0</accession>
    <name>D0Z4I0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000438</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304365.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000438"/>
    <dbReference type="EnsemblBacteria" id="EEZ39418">
        <property type="protein sequence ID" value="EEZ39418"/>
        <property type="gene ID" value="VDA_000438"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0790">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="366" mass="41642" checksum="226075AA2B3981D9" modified="2010-01-19" version="1">MKKLLLSSLVILSGCTLDSNNEMQNTTDNTITNIQQNIDKLTELDQIISTIEDEKTSDTELKKQLEKLAYMANENSEAMLYLASLYEEGDIISKNLALARSYYSKSSQKNNTLARYYYALMLIDGRGGETNHKEAKELLQTNIKDNHEQSTYALAYLHFIDKDYQKTINILSTKKSIDSPSSKYLLGISLLEQNQNIDKAIELLTQSSTEKNIYASHALGKIYAHGKHGQLKDPKKSFFYLKQAVQDNDPNALYDLAMLTLENPEFIDNDYNASIEKLIHADKYGNKFASFEIAKLYDQGNIVKQNYEKAIYWYKKSAEKGNNRAMYNLASMYANGDGVSVSMSDAEFWLKQSAQYGNQRAIELLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4V1</accession>
    <name>D0Z4V1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative type III export protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000184</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306541.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000184"/>
    <dbReference type="EnsemblBacteria" id="EEZ39168">
        <property type="protein sequence ID" value="EEZ39168"/>
        <property type="gene ID" value="VDA_000184"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031N4P">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1531204at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030257">
        <property type="term" value="C:type III protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030254">
        <property type="term" value="P:protein secretion by the type III secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013349">
        <property type="entry name" value="T3SS_YopR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041814">
        <property type="entry name" value="YopR_core"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09025">
        <property type="entry name" value="T3SS_needle_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="173" mass="19504" checksum="24311E4283273147" modified="2010-01-19" version="1">MKVENNSLNYALSQVQQPDKVDPHSSNKMSRLMSESALDYSSSNKNASPVQKSTDIVSQSEAKVTAIKEWYALSQERSVKGTDKASPELLGSFSGRLLADPPKDREELKVLLSEHFPLGAQKEQALWHSWAKLQDIPDQELLLDMVRKELSFVIQINSMVKNMLTYSHKLELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z545</accession>
    <name>D0Z545_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fimbrial protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000095</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306832.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000004.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39079">
        <property type="protein sequence ID" value="EEZ39079"/>
        <property type="gene ID" value="VDA_000095"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3847">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2065691at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007047">
        <property type="entry name" value="Flp_Fap"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04964">
        <property type="entry name" value="Flp_Fap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="69" mass="7259" checksum="20F3B4AF86CFCBE1" modified="2010-01-19" version="1">MLLNTYVKLQNFFKDERGVTAIEYAIIGVAVSAIVLAVFAGDANSLKTALSGAVTTITDNITSANNIKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z582</accession>
    <name>D0Z582_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Conjugative transfer protein TrbC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000013</name>
        <name evidence="3" type="ORF">VDA_000042</name>
        <name evidence="4" type="ORF">VDA_000132</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000008">
        <property type="protein sequence ID" value="EEZ38987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="ADBS01000005">
        <property type="protein sequence ID" value="EEZ39057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000013"/>
    <dbReference type="EnsemblBacteria" id="EEZ38987">
        <property type="protein sequence ID" value="EEZ38987"/>
        <property type="gene ID" value="VDA_000013"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39057">
        <property type="protein sequence ID" value="EEZ39057"/>
        <property type="gene ID" value="VDA_000042"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39116">
        <property type="protein sequence ID" value="EEZ39116"/>
        <property type="gene ID" value="VDA_000132"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5030AFU">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019106">
        <property type="entry name" value="T4SS_TrbC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014113">
        <property type="entry name" value="T4SS_TrbC_subgr"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09673">
        <property type="entry name" value="TrbC_Ftype"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02742">
        <property type="entry name" value="TrbC_Ftype"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5007650149" evidence="1">
        <location>
            <begin position="21"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ38987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="215" mass="23387" checksum="B94634E506DD5A81" modified="2010-01-19" version="1">MKLEKLMLAALFSLTLPVHAWTEQEAKATQQQKEAQAASFFMPETQQSAIQAHLKAKQYQSMATSLGQTANQKVIPSQNPNAAPPSVMIFASLGMPKTSLKQLLHQANNKHIPIVIRGVTVGGFTQTAQLVKALVLPKDNQKPLGGMSINPIWFKQFGINRVPAFVVMKPGACQGKPPCDPKNFDVVYGNVSLFDALNTIATHGDHAHIARKALQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5G0</accession>
    <name>D0Z5G0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000067</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000006">
        <property type="protein sequence ID" value="EEZ39012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39012">
        <property type="protein sequence ID" value="EEZ39012"/>
        <property type="gene ID" value="VDA_000067"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031P2U">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1700776at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="71"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="178"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="108"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="335" mass="36632" checksum="7730458D1CEC81E6" modified="2010-01-19" version="1">MNNTMIKGLCIALSVATAALSATLTTKFMFSIGEDMGSPQLMASLGLLLDLAKCATPLFIIFLWSQKMRLASMLALVLSITLSAVSFSASVVALESGVTASQQNSVSYQHIETQINDYRDQIVDLRQLAQRQQDAKQITKSQKTLSQIPALLAHVDKLSTQQSQLSSGDSVVSKYGMIISYITAAALELLSWMFVCVSFALKKAKHTQAQSGTVVHTHENLSVQPIDLKTEHTQTQSHLFTEVTHSCKLECANDACFSTDCESCIIGCEHSQSTKCDTQLYFDIRDAILAKEITPSIRGVSSKFKGVSRGLINHVLTDLYQTGILKNFRNGYAFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5G5</accession>
    <name>D0Z5G5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000072</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000006">
        <property type="protein sequence ID" value="EEZ39017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39017">
        <property type="protein sequence ID" value="EEZ39017"/>
        <property type="gene ID" value="VDA_000072"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031PX9">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="45" mass="5419" checksum="C93AFAA87441D17A" modified="2010-01-19" version="1">MPLDEKQLLWDAYMTLDHGNHDERLSMLENLKRYFEKVGKPTKVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5H9</accession>
    <name>D0Z5H9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hypothetical type II secretion protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000086</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GSP E family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000006">
        <property type="protein sequence ID" value="EEZ39031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005307192.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000006.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000086"/>
    <dbReference type="EnsemblBacteria" id="EEZ39031">
        <property type="protein sequence ID" value="EEZ39031"/>
        <property type="gene ID" value="VDA_000086"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2804">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="749544at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001482">
        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00437">
        <property type="entry name" value="T2SSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T2SP_E" evidence="2">
        <location>
            <begin position="98"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="519" mass="57807" checksum="9828F5A2FB7804A4" modified="2010-01-19" version="1">MNHTVLRDPTITRLCLDDGHTCVTEQGEILCANPHSAKLDDIIEAVQSLSFMAGQSPIITSVSQDYIETLLEVLTHSTHSPQDKEKESLLGLHLVALCQAAVDKGASDIHIEVYRKTTRYLIRVDGRREILARFADGQSALHQDRSKGIDLSSYVFSTLGNQDVNEREPANDSFDVNLTWNEKPKTFEFRAALMPLDRGIKLTLRCLTPRDKPLELSDMDLPSSYTDQLIRAVNQRGGAIVITGPMGSGKSSLIYALLDTVDSTARCIHSLEDPVEFEQAGICKTAVEPNTETKLGSGIYKDYAYYAKEQLRHDIDVAPFGELRDHAAAKEFCRKAETGGLAITTLHTNSVLGIPQTFIEQMGISPAIVAAPDLMRLFVHQKLVRKLCPHCALSYQEAIESPRTKAKAQLLSTLLPNHYQHCRVKSPQGCSACGGKGEKGRLVVMELVVLDDSDRQYIFAQDYLAWKQSLKSRGWPDIRDHTLSRIKRGQVDIESASEQINDLMPIKADEVYKNMMEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5I0</accession>
    <name>D0Z5I0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000087</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000006">
        <property type="protein sequence ID" value="EEZ39032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005307196.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000006.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000087"/>
    <dbReference type="EnsemblBacteria" id="EEZ39032">
        <property type="protein sequence ID" value="EEZ39032"/>
        <property type="gene ID" value="VDA_000087"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1459">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1704508at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="112"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="151"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="303"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="329" mass="35683" checksum="79E1FAD094262893" modified="2010-01-19" version="1">MKSFNQLLFFKNEQITLLEQWKNCDEYGLTTKQFCEALIENGTSATKEIGQAGRDAPAHGKHFTDVLMDWMPPMIVCAIATAEKAGDRQAGLDAAINQLQGGQNIIFNIVKALWFPFVLMIVTGALGLYVSDEILKSLTEKEGMGQTMNTIVSTYGLPIAIMLIALLIATALALPTLTGALRKNLDNLPIFSIYKTATAASVLNTLGNLLACGLKLDDALQAMGTNSVPYVRAHIELMRQQRIGQMNLGEIVDTGLILPFELGTLKILGGHAEYAKLLLKSAHNHQTNVDKRLSRMSNSLNKIGLLLVISLLGGLIGTAISQLLSTVNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVJ8</accession>
    <name>D0YVJ8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001578</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298316.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001578"/>
    <dbReference type="EnsemblBacteria" id="EEZ40552">
        <property type="protein sequence ID" value="EEZ40552"/>
        <property type="gene ID" value="VDA_001578"/>
    </dbReference>
    <dbReference type="GeneID" id="57342362"/>
    <dbReference type="eggNOG" id="COG2719">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="507759at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007390">
        <property type="entry name" value="Spore_V_R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30029">
        <property type="entry name" value="PTHR30029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04293">
        <property type="entry name" value="SpoVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="509" mass="60347" checksum="ED49D36DB418E02E" modified="2010-01-19" version="1">MATSTKSKMLSDGPDWTFNLLEQYHQEIKRIAKHYRLDTYPNQIEVITAEQMMDAYSSIGMPINYHHWSFGKRFIETERGYKHGQMGLAYEIVINSDPCIAYLMEENTITMQALVMAHACYGHNSFFKGNYLFKTWTDASSIIDYLLFARNYITDCEEKYGVDEVEKLLDSCHALMNYGVDRYKRPQKISLVEETARQKAREDYLQTQVNALWRTIPVHKELEQEKPKERFPSEPQENILYFFEKHAPLLEPWQREVVRIVRKVSQYFYPQKQTQVMNEGWATFWHYTIMNHLYDEGLVSERFIMEFLHSHTNVVAQPSYNSPYYNGINPYALGFAMFQDIRRICENPTEEDKYWFPDIAGSNWLDTVHFAMENFKDESFISQFLSPKVMRDFKLFAVDDNDRHNYVEISAIHNEEGYRMIREKLSSQYNLSNNEPNIQVWNVDLRGDRSLTLRYIPHNRIPLADSHKEVIKHLHRIWGFDVILEQEEPDGRAKILETCPPKTNYNTEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVM6</accession>
    <name>D0YVM6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hypothetical hydrolase of alkaline phosphatase superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001595</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298345.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001595"/>
    <dbReference type="EnsemblBacteria" id="EEZ40568">
        <property type="protein sequence ID" value="EEZ40568"/>
        <property type="gene ID" value="VDA_001595"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3083">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1067869at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008484">
        <property type="term" value="F:sulfuric ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012159">
        <property type="entry name" value="YejM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024588">
        <property type="entry name" value="YejM_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11893">
        <property type="entry name" value="DUF3413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004950">
        <property type="entry name" value="Mmb_sulf_HI0842"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="172"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3413" evidence="3">
        <location>
            <begin position="6"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="2">
        <location>
            <begin position="259"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF11893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="622" mass="71398" checksum="8AB12B0E65B1A2E3" modified="2010-01-19" version="1">MVTSGTQYKDKVSQLISWGHWFSFFNIIAAMLLGTRYIIHSEWPETILGQLYLVLSWVGHFGFLVFAIYILILFPASFIIPSQRVMRFFGVSIATVGFTALLLDTHAYQTVDLHLSPLVWDLLLSGEKTDLNTSWQYLFVVVPVFFLFELVLSETIWRKLRKLSRKRVGGPIALIFGLSFLSSHLLYIWADANLYHPITMQRSNFPLSYPMTAKSFMEKHGLLDRQEYKKRQEKQGVDESDQIRYPIEKLNYSDQGTNQNILFIMIDGLRSDMVNAETMPYLSRFAQNNLDYTNHYSTGNNNRNGIFGLFYGLPGSYSNSMQLAKKQPILLNTLADRGYDFGLFSGDDFNSPIYQDLLFTPQEIDASTTAKERSEKPSDHLAIAEWDQWLTTETDKPWFSYIELTAVQDFEEGGSYVAKFSPSIGSKLKHNQNVDSTLLLRNSYRNAAFHVDQQLEKILTQLKEKELLNNTIVIITANHGTEFNETGSNTWGADTNFSQYQIKVPLIIHWPEHSAQQISRITSHLDIVPTIMESVLHVASTPSNYSSGVSLFESDPSRRWILAGDDKNIVVVRQNNTTVVDKYGNYRVYDPNYQLKEEGKPKLSTLMQVMHELKRFYQPNNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVP3</accession>
    <name>D0YVP3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Ferric iron ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_001208</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001208"/>
    <dbReference type="EnsemblBacteria" id="EEZ40186">
        <property type="protein sequence ID" value="EEZ40186"/>
        <property type="gene ID" value="VDA_001208"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015408">
        <property type="term" value="F:ABC-type ferric iron transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03259">
        <property type="entry name" value="ABC_Carb_Solutes_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015853">
        <property type="entry name" value="ABC_transpr_FbpC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013611">
        <property type="entry name" value="Transp-assoc_OB_typ2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08402">
        <property type="entry name" value="TOBE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="6"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ40186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="346" mass="38079" checksum="0294C2091452B30B" modified="2010-01-19" version="1">MINPALTIENLTCCYHGQAVLQQLSLEVKQGEIVCLLGASGCGKTTLLKSIAGLLPLSSGKMVIGDTVVADSGVWLPPEQRNIGMIFQDYALFPHLTVAQNIAFGLHDWSKDRVTDKVAQMLELVHLQGLDNRYPHQLSGGQQQRVAIARALAQEPDLILLDEPFSNIDTQVRHGLIRDIRQIFKQQGVTAIFVTHSREEAFAFADRMAVMNHGIIEQFGPATELYYRPSSRFVAEFLGTGSYLPAQVTADALTTPFGHVPTSSLAVMQQGSSVDWLLRPQNISLAPNFDGKGIIIEQVFMGDCCRYTVDYLGHQLVVNSHHILQVGERVDIAIEPHEPVVFAKAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVT2</accession>
    <name>D0YVT2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Agmatinase</fullName>
            <ecNumber evidence="5">3.5.3.11</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001997</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the arginase family. Agmatinase subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.5.3.11" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299129.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001997"/>
    <dbReference type="EnsemblBacteria" id="EEZ40965">
        <property type="protein sequence ID" value="EEZ40965"/>
        <property type="gene ID" value="VDA_001997"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0010">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1598732at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008783">
        <property type="term" value="F:agmatinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901564">
        <property type="term" value="P:organonitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005925">
        <property type="entry name" value="Agmatinase-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006035">
        <property type="entry name" value="Ureohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020855">
        <property type="entry name" value="Ureohydrolase_Mn_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11358">
        <property type="entry name" value="PTHR11358"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00491">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036979">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="SSF52768"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01230">
        <property type="entry name" value="agmatinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01053">
        <property type="entry name" value="ARGINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51409">
        <property type="entry name" value="ARGINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="307" mass="33474" checksum="D616AABE03CAD9FE" modified="2010-01-19" version="1">MNDLFTKTDYSLYSNAMTFVRVPYVRNPINTDADMVILGAPLDLATSGRPGARLGPDAIRKASVNLAWESKKFPWDFNLLEEAKVIDAGDLVFDSGDAEDFTTRLEAAADAILADGKTVLTLGGDHFATLPLLRAYAKHYGKMALIHFDAHTDTYPHGSRYDHGTMFYHAPNEGLVDPAHSVQIGIRTEYKKENHGYHVINAMDANDLSVAEIVAQIKQTVGDMPVYLTFDIDCLDPAFAPGTGTPVIGGITSDRALKIIRGLTDINLVGMDVVEVSPAYDHSDLTSLAAATIALELMYLWVANRKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVW6</accession>
    <name>D0YVW6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">5-formyltetrahydrofolate cyclo-ligase</fullName>
            <ecNumber evidence="3">6.3.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001247</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>(6S)-5-formyl-5,6,7,8-tetrahydrofolate + ATP = 5,10-methenyltetrahydrofolate + ADP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10488"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57455"/>
            <dbReference type="ChEBI" id="CHEBI:57457"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.3.2" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297722.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001247"/>
    <dbReference type="EnsemblBacteria" id="EEZ40225">
        <property type="protein sequence ID" value="EEZ40225"/>
        <property type="gene ID" value="VDA_001247"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0212">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1816478at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030272">
        <property type="term" value="F:5-formyltetrahydrofolate cyclo-ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002698">
        <property type="entry name" value="FTHF_cligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024185">
        <property type="entry name" value="FTHF_cligase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23407:SF1">
        <property type="entry name" value="PTHR23407:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01812">
        <property type="entry name" value="5-FTHF_cyc-lig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006806">
        <property type="entry name" value="FTHF_cligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02727">
        <property type="entry name" value="MTHFS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="2">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="135"/>
            <end position="143"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR006806-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="193" mass="22492" checksum="E57A74BED530D6FC" modified="2010-01-19" version="1">MLLRQQLRQQIRQKRRQLTTQQQQEAAQQLLQQCQNASCFSQAQHIALYLSNDGEIDTTPLIHWLWQQHKQVYLPVLHPFSKGHLLFLHYSPHSQLICNKYGISEPKLNIEHVIPTQQLDLIATPLVAFDQQGQRLGMGGGYYDRTLQHWHTHKKGPMPIGLAHHCQQVRALPSEVWDVPLPQIITPTQHYIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW06</accession>
    <name>D0YW06_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">16S rRNA processing protein RimM</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001311</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001311"/>
    <dbReference type="EnsemblBacteria" id="EEZ40286">
        <property type="protein sequence ID" value="EEZ40286"/>
        <property type="gene ID" value="VDA_001311"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0806">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011961">
        <property type="entry name" value="16S_RimM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027275">
        <property type="entry name" value="PRC-brl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011033">
        <property type="entry name" value="PRC_barrel-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002676">
        <property type="entry name" value="RimM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036976">
        <property type="entry name" value="RimM_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05239">
        <property type="entry name" value="PRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01782">
        <property type="entry name" value="RimM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50346">
        <property type="entry name" value="SSF50346"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02273">
        <property type="entry name" value="16S_RimM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RimM" evidence="2">
        <location>
            <begin position="2"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="domain" description="PRC" evidence="3">
        <location>
            <begin position="54"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="132" mass="15010" checksum="BF4336D92F081F40" modified="2010-01-19" version="1">MKGEWQAFNVESWKRHGQGMVVKLEGLDVREDAQIFTNAEVAVQAEQLPALSDDEFYWRELYGMSVVTTEGYDLGVVTEILETGSNDVLVVKANLKDAFGQKERLIPFLDEQVIKSIDRTAQRIEVDWDPGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW57</accession>
    <name>D0YW57_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidoglycan lytic exotransglycosylase</fullName>
            <ecNumber evidence="2">4.2.2.n1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Murein hydrolase A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_001339</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Exolytic cleavage of the (1-&gt;4)-beta-glycosidic linkage between N-acetylmuramic acid (MurNAc) and N-acetylglucosamine (GlcNAc) residues in peptidoglycan, from either the reducing or the non-reducing ends of the peptidoglycan chains, with concomitant formation of a 1,6-anhydrobond in the MurNAc residue.</text>
            <dbReference type="EC" id="4.2.2.n1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="4.2.2.n1" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001339"/>
    <dbReference type="EnsemblBacteria" id="EEZ40314">
        <property type="protein sequence ID" value="EEZ40314"/>
        <property type="gene ID" value="VDA_001339"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2821">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019867">
        <property type="term" value="C:outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009254">
        <property type="term" value="P:peptidoglycan turnover"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14485">
        <property type="entry name" value="mltA_like_LT_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010611">
        <property type="entry name" value="3D_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026044">
        <property type="entry name" value="MltA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034654">
        <property type="entry name" value="MltA_3D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005300">
        <property type="entry name" value="MltA_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30124">
        <property type="entry name" value="PTHR30124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06725">
        <property type="entry name" value="3D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03562">
        <property type="entry name" value="MltA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019422">
        <property type="entry name" value="MltA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00925">
        <property type="entry name" value="MltA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="SSF50685"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MltA" evidence="6">
        <location>
            <begin position="53"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00030918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="302" mass="33848" checksum="4AFF1C81F4C28910" modified="2010-01-19" version="1">MDRKYGPLYRQLEKWIKTDGKVQDLTKYGIQAAQLGGSDDRGNVMFTGYYSPVLEIRHYPDAEYKYPVYAMPKCKGRCPSRAQIYAGALKGQGLELGYSKSMIDVFMMEVQGSGFVHYGDNDEMQYFGYAGKNGHRYVSIGKVLIDRGEVPRDKMSLKAIHDWAEKQSPAKLRELLEQNPSYVFFERRPSLDVKGSAGIPLLADSAVAGDRKYFPMGSVILAEVPKLNEAGHWTGKHQLQLFIVLDTGGAVKRNHFDIYHGRGEKAGIAAGHYKHFGRVWKLGLKGTATQDPWLMANGQLSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW75</accession>
    <name>D0YW75_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Uridylate kinase</fullName>
            <shortName evidence="6">UK</shortName>
            <ecNumber evidence="6">2.7.4.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Uridine monophosphate kinase</fullName>
            <shortName evidence="6">UMP kinase</shortName>
            <shortName evidence="6">UMPK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">pyrH</name>
        <name evidence="8" type="ORF">VDA_001360</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the reversible phosphorylation of UMP to UDP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>ATP + UMP = ADP + UDP</text>
            <dbReference type="Rhea" id="RHEA:24400"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.22"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="6">Allosterically activated by GTP. Inhibited by UTP.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 6">Pyrimidine metabolism; CTP biosynthesis via de novo pathway; UDP from UMP (UMPK route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the UMP kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.22" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297918.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001360"/>
    <dbReference type="EnsemblBacteria" id="EEZ40335">
        <property type="protein sequence ID" value="EEZ40335"/>
        <property type="gene ID" value="VDA_001360"/>
    </dbReference>
    <dbReference type="GeneID" id="57339731"/>
    <dbReference type="eggNOG" id="COG0528">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1043239at2"/>
    <dbReference type="UniPathway" id="UPA00159">
        <property type="reaction ID" value="UER00275"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033862">
        <property type="term" value="F:UMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044210">
        <property type="term" value="P:'de novo' CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04254">
        <property type="entry name" value="AAK_UMPK-PyrH-Ec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01220_B">
        <property type="entry name" value="PyrH_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011817">
        <property type="entry name" value="Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015963">
        <property type="entry name" value="Uridylate_kinase_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005650">
        <property type="entry name" value="Uridylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02075">
        <property type="entry name" value="pyrH_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 6" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AA_kinase" evidence="7">
        <location>
            <begin position="11"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Involved in allosteric activation by GTP" evidence="6">
        <location>
            <begin position="23"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="15"/>
            <end position="18"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>UMP</name>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>UMP</name>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="138"/>
            <end position="145"/>
        </location>
        <ligand>
            <name>UMP</name>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ40335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="242" mass="26085" checksum="84FFEDB4136C610A" modified="2010-01-19" version="1">MTTNPKPAYQRILLKLSGEALQGAEGFGIDANVLDRMAQEIKELVELGVQVGLVIGGGNLFRGAGLAEAGMNRVVGDHMGMLATVMNGLAMRDSLHRAYVNARVMSAIPLNGVCDNYNWADAISQLRQGRVVIFSAGTGNPFFTTDSAACLRGIEIEADVVLKATKVDGVFTADPVKNPEATLYTQLSYQDVLEKELKVMDLAAFTLARDHGMPIRVFNMNKPGALRRVVMGEQEGTLISND</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWG3</accession>
    <name>D0YWG3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001422</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40396">
        <property type="protein sequence ID" value="EEZ40396"/>
        <property type="gene ID" value="VDA_001422"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="41" mass="4024" checksum="93977ACC26593AA4" modified="2010-01-19" version="1">MAAICGASGTTAGEAATVAEASKDAETATEQKSAADFFMVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWJ1</accession>
    <name>D0YWJ1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Putative pre-16S rRNA nuclease</fullName>
            <ecNumber evidence="2">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001233</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the YqgF HJR family.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297693.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001233"/>
    <dbReference type="EnsemblBacteria" id="EEZ40211">
        <property type="protein sequence ID" value="EEZ40211"/>
        <property type="gene ID" value="VDA_001233"/>
    </dbReference>
    <dbReference type="GeneID" id="57339889"/>
    <dbReference type="eggNOG" id="COG0816">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2075502at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000967">
        <property type="term" value="P:rRNA 5'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16964">
        <property type="entry name" value="YqgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00651">
        <property type="entry name" value="Nuclease_YqgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005227">
        <property type="entry name" value="YqgF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006641">
        <property type="entry name" value="YqgF/RNaseH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037027">
        <property type="entry name" value="YqgF/RNaseH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33317">
        <property type="entry name" value="PTHR33317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03652">
        <property type="entry name" value="RuvX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00732">
        <property type="entry name" value="YqgFc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00250">
        <property type="entry name" value="RNAse_H_YqgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="YqgFc" evidence="3">
        <location>
            <begin position="5"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="141" mass="15721" checksum="CB3E555067228B1E" modified="2010-01-19" version="1">MSQSRTVLAFDYGTKSIGVAIGQEITGTAQPLKALKARDGIPSWEAIEQILKEWQPDLVVVGLPLDMSGHELETITPRAKKFANRLHGRFGCQVELHDERLSTAEARAELFEFGGYRNLSKGNIDSQSAVVILESWFENQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWS2</accession>
    <name>D0YWS2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hypothetical iron-regulated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001467</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298114.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001467"/>
    <dbReference type="EnsemblBacteria" id="EEZ40441">
        <property type="protein sequence ID" value="EEZ40441"/>
        <property type="gene ID" value="VDA_001467"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3016">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1240854at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14727">
        <property type="entry name" value="ChanN-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007314">
        <property type="entry name" value="Cofac_haem-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016773">
        <property type="entry name" value="Fe3_uptake_reg_CjrA_prd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04187">
        <property type="entry name" value="Cofac_haem_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF020419">
        <property type="entry name" value="Fe_uptake_reg_CjrA_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cofac_haem_bdg" evidence="1">
        <location>
            <begin position="47"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="312" mass="34919" checksum="0CF4670AF58AB426" modified="2010-01-19" version="1">MKAWLSLTIAALLTGCATTPQPSSKLNTFYDYRITDSNLTAITIKQLAKQLENADVVLVGEWHGHPAAHLLQAQLLAALYQQNADLTLSMEQFTRDKQGVLNDYLAGKIGESTLTKEANAWPNYTSDYRPLVEFAKQNQLDVLAANAPKSIVRCIGQQGGNYLNKLPKNERQWVASKLTLSNDAYKQKFKASMHHGDEAKTERQFAAQTAWDDTMAESIVNYLVQHPDHQIMHTAGRFHVMDGLGTASRIKARNPKLQVALVTPVTKNDDVTAGSIDYRVEMMSLPKSYVQKDKMMAAMKMIQQRNSNLKCY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWV8</accession>
    <name>D0YWV8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">UDP-glucose 6-dehydrogenase</fullName>
            <ecNumber evidence="4 7">1.1.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">VDA_001531</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>H2O + 2 NAD(+) + UDP-alpha-D-glucose = 3 H(+) + 2 NADH + UDP-alpha-D-glucuronate</text>
            <dbReference type="Rhea" id="RHEA:23596"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58052"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="1.1.1.22"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Nucleotide-sugar biosynthesis; UDP-alpha-D-glucuronate biosynthesis; UDP-alpha-D-glucuronate from UDP-alpha-D-glucose: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.22" evidence="4 7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298225.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001531"/>
    <dbReference type="EnsemblBacteria" id="EEZ40505">
        <property type="protein sequence ID" value="EEZ40505"/>
        <property type="gene ID" value="VDA_001531"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1004">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="647136at2"/>
    <dbReference type="UniPathway" id="UPA00038">
        <property type="reaction ID" value="UER00491"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009331">
        <property type="term" value="C:glycerol-3-phosphate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004367">
        <property type="term" value="F:glycerol-3-phosphate dehydrogenase [NAD+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003979">
        <property type="term" value="F:UDP-glucose 6-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006072">
        <property type="term" value="P:glycerol-3-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000271">
        <property type="term" value="P:polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006065">
        <property type="term" value="P:UDP-glucuronate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006168">
        <property type="entry name" value="G3P_DH_NAD-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017476">
        <property type="entry name" value="UDP-Glc/GDP-Man"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014027">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036220">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014026">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001732">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028357">
        <property type="entry name" value="UDPglc_DH_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00984">
        <property type="entry name" value="UDPG_MGDP_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03721">
        <property type="entry name" value="UDPG_MGDP_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500134">
        <property type="entry name" value="UDPglc_DH_bac"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000124">
        <property type="entry name" value="UDPglc_GDPman_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00077">
        <property type="entry name" value="GPDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00984">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52413">
        <property type="entry name" value="SSF52413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03026">
        <property type="entry name" value="NDP-sugDHase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 10" id="KW-0520">NAD</keyword>
    <keyword evidence="5 7 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDPG_MGDP_dh_C" evidence="11">
        <location>
            <begin position="300"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="142"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="242"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8">
        <location>
            <position position="253"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="29"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="250"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="256"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="306"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="307"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="314"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="388"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR000124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR500134-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR500134-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR500134-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ40505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="388" mass="43047" checksum="F05736B36066D792" modified="2010-01-19" version="1">MKITVVGTGYVGLSNAVLLAQNHQVVALDIIQEKVDLINNRLSPIVDAEIEQYLREKPLNLVATTDSETAYDGADFVIIATPTDYDTQTNYFNTGSVEAVIKDVMVKNPTATMVIKSTIPVGYTQRIKQELGCENLIFSPEFLREGRALYDNLYPSRIIVGEQSERAQVFAHLLAEGAIKDDIPMLFTNSTEAEAVKLFSNTYLAMRVAYFNELDTYAATNGLDARQIIEGVGLDPRIGNHYNNPSFGYGGYCLPKDTKQLRANYCDVPNNIIGAIVDANTTRKDFIADSIIAKQPKVVGVYRLIMKSGSDNFRASSIQGIMKRIKAKGIEVVVYEPVLKEDDFFNSKVIRDLDTFKAMSDVIVSNRMAQELADVADKVYTRDLFGAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWY2</accession>
    <name>D0YWY2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hypothetical phage shock protein C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001815</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001815"/>
    <dbReference type="EnsemblBacteria" id="EEZ40783">
        <property type="protein sequence ID" value="EEZ40783"/>
        <property type="gene ID" value="VDA_001815"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1983">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="67" mass="7964" checksum="EBC32129590A6AF6" modified="2010-01-19" version="1">MPQERTDQQETFKEHNIKQKPWQAGHPPGQILQNVELELSTMERKLRTMEAYVTSPAFDVEREIRKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX03</accession>
    <name>D0YX03_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Probable pyocin R2_PP tail fiber protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002056</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002056"/>
    <dbReference type="EnsemblBacteria" id="EEZ41024">
        <property type="protein sequence ID" value="EEZ41024"/>
        <property type="gene ID" value="VDA_002056"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5301">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="184" mass="20796" checksum="4FC67553973A4EDC" modified="2010-01-19" version="1">MYRYNVRSYENMLGVVQFTKAGLAELISANNQGLKGALKWIAAGDRSYQPSPDQKSLYSERQRELISDWEEIGPTQLRMGAAFKGNLEYEVREVGFFLESGTLLAVYSRPNQLLTYKSASASWIQKFTLDVSPLPTDSITFIEGNNDLNLLLGEELATMATAQIGNMARHLELLFRFNELEKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX09</accession>
    <name>D0YX09_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002066</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299329.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002066"/>
    <dbReference type="EnsemblBacteria" id="EEZ41034">
        <property type="protein sequence ID" value="EEZ41034"/>
        <property type="gene ID" value="VDA_002066"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0810">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="327"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="330"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="417"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="450" mass="52544" checksum="7387B8E8AEBDE199" modified="2010-01-19" version="1">MDRAYNETTDTIEYAAKINEKEESLRKKHLEKANYKCPNFLCRYDATPCAFGDEYIQPAHFRYLNGHVTNCTFDKASGVFIEEKDKNGNYSYRQSYITELIEPKPNQNKSSSNNTILKDSMERSSSSANRKNVKNGTSKRKVQVSSYLSAPTNFYLQDPINNASLKFTVLKRMGTYRSQYQKISNSFTKYKNNYIFYSPIYSYNEIKLNENEIIVTLLPKDSLTNKRYELHLLCQEWPEQHKKAVYDELKRALKTSKDNYKNNSSECVNLFFLGKQDKLNSNIFLCEYAEFLYVYAGSKFNLSYNKFGTYDFLEKKVDNKDKKICIEQPQPQPQPQPQPQPQPQPQPQPQPQPQPQPQPQPQPQPQPQPQPQPQPQPQPQPQPQPQPQPQPQPQPQPQPQPQPQPQPQPQPQFQNKKVTKKNDERDKIVRVGNRGLKEKIKSYFNKLFRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX26</accession>
    <name>D0YX26_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Chitinase</fullName>
            <ecNumber evidence="4">3.2.1.14</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001901</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.2.1.14" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298901.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001901"/>
    <dbReference type="EnsemblBacteria" id="EEZ40869">
        <property type="protein sequence ID" value="EEZ40869"/>
        <property type="gene ID" value="VDA_001901"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3325">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1081028at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004568">
        <property type="term" value="F:chitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54556">
        <property type="entry name" value="SSF54556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018644" evidence="2">
        <location>
            <begin position="24"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="3">
        <location>
            <begin position="31"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="436" mass="48856" checksum="B669D3473355B9D9" modified="2010-01-19" version="1">MNQVKPVVLTLLSTILFSSVVQAEEIQTTKPVIAAYYPDWKVYNPRKSYSAGSIPTDKLTHVIYAFLGVCGPHSASPANIQKIMAQQCRGKPTGTAVIVDNFAALQKQLPGKTDYKVRYKGNFGQLSALVKADPELVVLPSFGGWTLSEPFHTVVINPTYRKNFVVSAIDLLERYPFFGGIQLDWEYPGGNGLSGKGKDNLDQEKIGFTALLKELDHGLETLSLKHHRQYELSAAVSASNKNINNIDWPQVAQYLDHIFLMSYDFLGGWENIVGHHANLFATNKTPNQVSVDQQVNALLQRGVSHQQIIVGVPFYGRGWQQVEDFTPNTLEGLTSQSGLKKGSDLDDPGYFTYQDIATHLLNNPKLGYQYYYDEQAQAAVLYHPTKKEFITFDDQRSIKAKTDYVKQNRLGGIFTWEITADKDNQLIELISTELNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX42</accession>
    <name>D0YX42_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hypothetical carboxypeptidase G2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001824</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298776.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001824"/>
    <dbReference type="EnsemblBacteria" id="EEZ40792">
        <property type="protein sequence ID" value="EEZ40792"/>
        <property type="gene ID" value="VDA_001824"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0624">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1015417at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017150">
        <property type="entry name" value="Pept_M20_glutamate_carboxypep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037238">
        <property type="entry name" value="Carboxypeptidase_G2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="3">
        <location>
            <begin position="177"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR037238-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="376" mass="40835" checksum="90FE482FCFBD0AAB" modified="2010-01-19" version="1">MATLFDLSTYISQLERLVNVDCGSHTPAGISKIADIVTPMFEQIGFTVIRHQLDPNAGPCLEITNKPDATEYDVMLSGHMDTVFPEGTVAKRPMSFDNEKIYGPGATDMKSGILSAWYALQGLTLDELDRFAVVIALNCDEEIGSIYSRQWLETLARKSRQVLVCEAARPSGNLIRSRKGNAKYEIEFHGVASHAGSALAEGVSAIYELSHWSLAIKDMVNLETGTTMNVGIIEGGMAVNVVPDYAKATVDLRFWDTEEAEAIDAKLQQMAKNPFESGASVVVNRVTFKPSMQPSADTEALITMVSEEADKLALTYGWEDAGGGSDGNFTAAVGTPTLDGFGPMGAGFHSDKEYLLIDSIEPRIQLLTNVLRRLIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX43</accession>
    <name>D0YX43_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hypothetical nudix hydrolase YeaB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001837</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298789.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001837"/>
    <dbReference type="EnsemblBacteria" id="EEZ40805">
        <property type="protein sequence ID" value="EEZ40805"/>
        <property type="gene ID" value="VDA_001837"/>
    </dbReference>
    <dbReference type="GeneID" id="57342045"/>
    <dbReference type="eggNOG" id="COG0494">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1623169at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010945">
        <property type="term" value="F:CoA pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03426">
        <property type="entry name" value="CoAse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045121">
        <property type="entry name" value="CoAse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12992">
        <property type="entry name" value="PTHR12992"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="1">
        <location>
            <begin position="37"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="199" mass="22708" checksum="B535C4B60731154C" modified="2010-01-19" version="1">MNENHLLNKLVLTPLIQDYNASHRARISQHLPPNYQFKQAAVLIPLVKRPQGWQVILTQRAHHLKHHPGQIAFPGGRFEPEDGDLMTTALRETKEETGIDCTKGQILGRLPALETVSGYRVTPFFSTVMENYQVKIDPNEVAEIFEVPIKFLLNPVNIKSQKSLIKGEYHTIYAIPFSHYSIWGATAQMIKLLSDQIWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXH0</accession>
    <name>D0YXH0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sulfate permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001677</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298497.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001677"/>
    <dbReference type="EnsemblBacteria" id="EEZ40648">
        <property type="protein sequence ID" value="EEZ40648"/>
        <property type="gene ID" value="VDA_001677"/>
    </dbReference>
    <dbReference type="GeneID" id="57342242"/>
    <dbReference type="eggNOG" id="COG0659">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="967266at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015116">
        <property type="term" value="F:sulfate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="179"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="241"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="282"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="311"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="336"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="369"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="2">
        <location>
            <begin position="416"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="518" mass="55178" checksum="20E139AA0B875B41" modified="2010-01-19" version="1">MFEFPSFSRQSVKNDILSGLTVALALIPEAVAFAFVAGVDPMVGLYAAFIVGLVTAILGGRPGMISGATGAMAVVMVSLVADHGIQYLFAAIMLAGVFQILAGVFKLGKFIRMVPHPVMIGFVNGLAIVIFLAQLGQFKVTNAAGQLEWMQGTQLYIMLGLVALTMAIIYFLPKLTKAVPSSLVAILTVTALVHVVGLDSRTVIDFVRSMSGNPNATLAGSLPTFALPEVGFNLETLRIILPYSLILAAVGLIESLLTLTVIDEMTGTRGHGNRECMGQGVANITCSVFGAMGGCAMIGQSMININSGGRGRLSGITGAVGLMLFVLFGAPLIEMIPVAALVGVMFMVVIGTFEWASFKMMRKVPKHDFFTIILVTCVTIAADLAVAVLVGVIYSALVFAWNHAKRIYASTHTDENGAKIYRVNGPLFFGSAAHFLELFDAKNDPNNIIIDFAQSRVADHSAIEAIDTIAERYANQGKTLHIKHLSPECRSLLKKAGNLVEVNMLEDPTYKVATDTLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXL0</accession>
    <name>D0YXL0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001725</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298583.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001725"/>
    <dbReference type="EnsemblBacteria" id="EEZ40695">
        <property type="protein sequence ID" value="EEZ40695"/>
        <property type="gene ID" value="VDA_001725"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2501">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2071059at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="145" mass="15789" checksum="644DA61C2472D301" modified="2010-01-19" version="1">MCEEIEVEALEIVVSAQPIELYKVLKIANLVSGGGEAKYAISEGYVAVNGEIEQRKRCKMYDGDVIEFNGEFYVVLCDQPVQEPVEKTITDIKPMAKKAPKPAEKKKTANHKSKSAGNRSVTKKSANKAAGGKPDSTTGRKPISF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXQ5</accession>
    <name>D0YXQ5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulators LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001754</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298634.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001754"/>
    <dbReference type="EnsemblBacteria" id="EEZ40722">
        <property type="protein sequence ID" value="EEZ40722"/>
        <property type="gene ID" value="VDA_001754"/>
    </dbReference>
    <dbReference type="GeneID" id="57342155"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="750230at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="294" mass="33197" checksum="FCE77355567D5CF2" modified="2010-01-19" version="1">MKMSQIEMFIYAVNTGSIAEAARKLEKSRTTVSAALSALEDDLGVQLLTRSGNRITPTEMGQAIVNDCERITLIANDIIAKCEQHRDGVESMLRIVRDDSLPEELWRDLIRQMNTLFPKTSISIYISPTPEIVNMVEENLVDVAYGLLPSHQDSPRLYYSDLGQIRMMSVAHADHPLCKLQKVTSGDLERFKEVVIAYIDDDGLRAAASHSSNYLGLTFYEHLRDAVLDKAGWSYVPALLIKDYLRQGTLKMLKHNRAMNWQSYGEIVESESRRGAVVQWLSNQIANYLLDVSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXS8</accession>
    <name>D0YXS8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative nonspecific acid phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002091</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002091"/>
    <dbReference type="EnsemblBacteria" id="EEZ41059">
        <property type="protein sequence ID" value="EEZ41059"/>
        <property type="gene ID" value="VDA_002091"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0560">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1472357at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019872" evidence="1">
        <location>
            <begin position="23"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="341" mass="38607" checksum="1C3522DBD07368F3" modified="2010-01-19" version="1">MKFTHVALCALPFVSIPFSVFSMSCDNQGETLSLWQNSSPRSSLLTFVDKVTNVNSADYVPANERIAVIDNDGTLWPEKPMYTQFQFAFDQIKAKAKTNLDWGEKTPYKWVVDGDIQEVFKHSWSALLPILAQSQAGVTPSQYSSEVLSWLKTHKSSRFNRPYTSLVYQPMIQVIDYLKANQFDVYIVTGAGAAFVRPWSEAIYHIPAQNVIGTTFGYSYKQVNGKAQLFKNDKLIYVNDGPQKAINIETIIGKRPIVAIGNSTGDAAMLDWTTSQKGESFAMLIHHTDQEREWSYGPSSFEGKFTPELMNQAKTHGWNVVNMKNDWCQIFPTEKEERKLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXV4</accession>
    <name>D0YXV4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Putrescine-binding periplasmic protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_002117</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for the activity of the bacterial periplasmic transport system of putrescine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial solute-binding protein PotD/PotF family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299481.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002117"/>
    <dbReference type="EnsemblBacteria" id="EEZ41085">
        <property type="protein sequence ID" value="EEZ41085"/>
        <property type="gene ID" value="VDA_002117"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0687">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1264541at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019808">
        <property type="term" value="F:polyamine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015846">
        <property type="term" value="P:polyamine transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001188">
        <property type="entry name" value="Sperm_putr-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019574">
        <property type="entry name" value="Periplasmic_polyamine_BP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00909">
        <property type="entry name" value="SPERMDNBNDNG"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0574">Periplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019827" description="Putrescine-binding periplasmic protein" evidence="3">
        <location>
            <begin position="23"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Spermidine-binding" evidence="2">
        <location>
            <begin position="168"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>spermidine</name>
            <dbReference type="ChEBI" id="CHEBI:57834"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="323"/>
        </location>
        <ligand>
            <name>spermidine</name>
            <dbReference type="ChEBI" id="CHEBI:57834"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR019574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR019574-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="345" mass="39053" checksum="517D71985A6E2858" modified="2010-01-19" version="1">MKKWSSLLIGSALLSASLNVAAEETKDKQLVFMNWGPYISTELREQFTKETGIKVIYSTYESNETMYAKLRAHPEGYDLVVPSTYFVAKMRDEGMLQKIDKSKLTNFNQLDKNYLDKPFEPSNDYSIPHVIAMTGLAVNTDMYNPDDFNSWADLWRPELKGQLMLMDDTREVFHIALRKLGYSGNTTDPKQIDEAYEELKKLMPNVLVFNSDNPAAPYLSGEVGLGMLWNGSAAAAQKEGLPIKLIWPKEGGIFWVDSLAIAKNAKNVEAAHKMIDFLLRPEIAAKISEETGYLTAVEKSNAKYKDNPTLFPPQEDLDRGEWQDAVGTMNNRYENYFLELKAGDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXW2</accession>
    <name>D0YXW2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative formate dehydrogenase-specific chaperone</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002125</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299497.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002125"/>
    <dbReference type="EnsemblBacteria" id="EEZ41093">
        <property type="protein sequence ID" value="EEZ41093"/>
        <property type="gene ID" value="VDA_002125"/>
    </dbReference>
    <dbReference type="GeneID" id="57341745"/>
    <dbReference type="eggNOG" id="COG3381">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1995553at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020945">
        <property type="entry name" value="DMSO/NO3_reduct_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036411">
        <property type="entry name" value="TorD-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02613">
        <property type="entry name" value="Nitrate_red_del"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89155">
        <property type="entry name" value="SSF89155"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="200" mass="22410" checksum="F878367560E10B36" modified="2010-01-19" version="1">MNSHQTSSNQDAILRIEIYNLLAHLLRQSPSQDVLDWLADLDVEGTNDPHQSSMAAAWPLLKLAAQKATPIAVAEEYQDLFIGIGRGDVVPYGSWYLTGSLMEMPLAHLRSDLKQLGYERNESVKEPEDHIAALLEVMAMLVEGGDEHLQRTFFNRHLAPWCEKVSTDIKTAKSAVFYTAVGELALQFLTVEKTRFLQAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXW5</accession>
    <name>D0YXW5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002128</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002128"/>
    <dbReference type="EnsemblBacteria" id="EEZ41096">
        <property type="protein sequence ID" value="EEZ41096"/>
        <property type="gene ID" value="VDA_002128"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5032ZV5">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="54" mass="6234" checksum="467C012767931238" modified="2010-01-19" version="1">MDGDYTVLHISIPLPIQAWMEAYIGRHGELLEFKRKGFKDKGPKEKSRGRSCDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXZ0</accession>
    <name>D0YXZ0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein ImpI/VasC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002153</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299551.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002153"/>
    <dbReference type="EnsemblBacteria" id="EEZ41121">
        <property type="protein sequence ID" value="EEZ41121"/>
        <property type="gene ID" value="VDA_002153"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="550490at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017735">
        <property type="entry name" value="T6SS_FHA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SSF49879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03354">
        <property type="entry name" value="VI_FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="2">
        <location>
            <begin position="33"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="209"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="489" mass="55199" checksum="38B39DE688114501" modified="2010-01-19" version="1">MTEQNLLTLTVINTQFVAPGISVKKEFNSNGGTIGSSSSDGWFLTDNQRQIQQNHCQIVFRDGAFCITDNCNQTFINNQSMAVGWDKTARLNENDVLNIGRFVIRVSLHGDAKEKEGRLETFFIANNGLELDGEELDLIEQDQVCSVDDPLAALDAQEITQSIDLFGGEQDTRSKAINNPLLSNNEEWFGSQETIQADTERDVQSAMTLKKSQRTASYDKEPVATHSTSKQPVSKKTVPTAYLASSDNSIAPAQNSFYKDRVMDEKTLDLLEEEVRQGFSYHSDPQLDSSEGNHLLTGPLLRGLGTKAGNPDDLAEMQLLSEEMGASLQSAIRGLLDLHQQVASSRYGVMNKNLQPIEDNPLRLGMDYEQTVQVMFDGERSPVHLSAPAAIEESLRTVKNHNEAVHQAISEALAQILQAFSPEVLQRRFNRYRRPGQHLNESPESWAWHMYQNYYQELTSNRQHGFDKLFWEIFDQAYDKRLREKQQEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY47</accession>
    <name>D0YY47_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Hydrogenase (acceptor)</fullName>
            <ecNumber evidence="6">1.12.99.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">VDA_002210</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>A + H2 = AH2</text>
            <dbReference type="Rhea" id="RHEA:12116"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:18276"/>
            <dbReference type="EC" id="1.12.99.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Heterodimer of a large and a small subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.</text>
    </comment>
    <dbReference type="EC" id="1.12.99.6" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299655.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002210"/>
    <dbReference type="EnsemblBacteria" id="EEZ41178">
        <property type="protein sequence ID" value="EEZ41178"/>
        <property type="gene ID" value="VDA_002210"/>
    </dbReference>
    <dbReference type="GeneID" id="57341646"/>
    <dbReference type="eggNOG" id="COG1740">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="798037at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009375">
        <property type="term" value="C:ferredoxin hydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051538">
        <property type="term" value="F:3 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008901">
        <property type="term" value="F:ferredoxin hydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033748">
        <property type="term" value="F:hydrogenase (acceptor) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.480.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027394">
        <property type="entry name" value="Cytochrome-c3_hydrogenase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006137">
        <property type="entry name" value="NADH_UbQ_OxRdtase-like_20kDa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037148">
        <property type="entry name" value="NiFe-Hase_small_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037024">
        <property type="entry name" value="NiFe_Hase_small_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001821">
        <property type="entry name" value="NiFe_hydrogenase_ssu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30013">
        <property type="entry name" value="PTHR30013"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14720">
        <property type="entry name" value="NiFe_hyd_SSU_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01058">
        <property type="entry name" value="Oxidored_q6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000310">
        <property type="entry name" value="NiFe_hyd_ssu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00391">
        <property type="entry name" value="hydA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 13" id="KW-0003">3Fe-4S</keyword>
    <keyword evidence="13" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="10 13" id="KW-0408">Iron</keyword>
    <keyword evidence="11 13" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="7 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 16" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Oxidored_q6" evidence="14">
        <location>
            <begin position="84"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="NiFe_hyd_SSU_C" evidence="15">
        <location>
            <begin position="250"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="217"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="255"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="258"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="283"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="289"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="298"/>
        </location>
        <ligand>
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="317"/>
        </location>
        <ligand>
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="320"/>
        </location>
        <ligand>
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR000310-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF14720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EEZ41178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="378" mass="40912" checksum="BCAFCD1312B03239" modified="2010-01-19" version="1">MDSHAALYELGKKRLAQLREMKPLRDESFQQKLESHGISRRDFMIWSATITSLLALPMPFNTMVAEAAELADRVPLIWLSMAECTGCSESFVRTTTPDISTILFEHVSLEYQEVLMAAAGMQAEENLDNAIKNYKGKYLLAVEGAIPTANNGTFLTIGNKAETGVDLIKRVTKDAAAIMCVGTCSSFGGVQAASPNPTGAKGVGAVVDLPVINVAGCPPNPANITGTLMYYIMFGRLPALDIFNRPKWAYGARVHDNCERRGHFDAGEFVLEFGDDNAKNGFCLFKMGCKGPYTFNNCPTERFNAHTSWPVLAGHGCIGCSEPDFWDDMADFEKPLSRKPLHGLDATADTIGAVTLGLTAVGIGAHAVSSIFAKKVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY57</accession>
    <name>D0YY57_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Coproporphyrinogen III oxidase, oxygen-independent</fullName>
            <ecNumber evidence="7">1.3.99.22</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_002220</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="1.3.99.22" evidence="7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299675.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002220"/>
    <dbReference type="EnsemblBacteria" id="EEZ41188">
        <property type="protein sequence ID" value="EEZ41188"/>
        <property type="gene ID" value="VDA_002220"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0635">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1130951at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034505">
        <property type="entry name" value="Coproporphyrinogen-III_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026332">
        <property type="entry name" value="HutW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13932">
        <property type="entry name" value="PTHR13932"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13932:SF9">
        <property type="entry name" value="PTHR13932:SF9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00311">
        <property type="entry name" value="heme_degradation_proteins_(Hut"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04107">
        <property type="entry name" value="rSAM_HutW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="6">
        <location>
            <begin position="68"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="463" mass="51764" checksum="7E5AAD991FCB06F4" modified="2010-01-19" version="1">MNQEHQIDINKLDESILGLHSPDPLRFAFSRKKSAHAGGMNTMVPAEQHQSLGLSLLSEEKKRSLEPYSQVKKRCLYVHIPFCRVRCTYCNFFQYASSQQLIDDYFAALMIELKLKAQQPWTQSAPFHAVYIGGGTPTDLTAQQVKQLGTMIRKHFPLTTDCELTLEGRINRFSDEMFDSALEGGFNRFSFGVQSFDTQVRRKAKRLDDREVVLDRIAALAATDQAPIVIDLLYGLPYQTLDVWQQDLEDFMTSGAHGVDLYQLIEMGGTPMKNLIDKGKLPEPADTQTKATMFLMGHDYMSHHHMRKLSVNHWARDNRERSLYNSLAKTTAEVLPLGAGAGGNIAGFGMMQHRTLDAYLAAIKRGELPIAMMTKQANQASLHAEIKASFDRGVLSRSSLDSIGGKGLYSSCLPLFKAWRENGLVEVNSHYVTLTLAGQFWAVTLAQALIEAITQQLNQSLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYA0</accession>
    <name>D0YYA0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002263</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299754.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002263"/>
    <dbReference type="EnsemblBacteria" id="EEZ41231">
        <property type="protein sequence ID" value="EEZ41231"/>
        <property type="gene ID" value="VDA_002263"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1075">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1573721at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012908">
        <property type="entry name" value="PGAP1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07819">
        <property type="entry name" value="PGAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="355" mass="40117" checksum="E6613482B75EF5AB" modified="2010-01-19" version="1">MKSPQSLFNQWRTHWQNQSQEWKDKIDMLLPSVSNDIVLAAFNGMMGDKLAARNSPYAITMALTDQDQVLSDQTNVLSKQYPNLSNKVVVCVHGWCMSDKQWLYQQHDHGQALKAYGYSPIYLNYNTGKHISLNGEEFAFRLEKLLQAWPVAIEELVIIGHSMGGLVTRSACYYAKEHQLNWLSQLTSFITLGTPHNGAPLAEMANWIDDNVKQKATFKLLNQLADIRSDGTRDLSCGYIIHQDWTQDRDPKLDKYLPPNPPKKRSELPEHVQCYAIASCVTSRRVDQQLHLIGDGLVPVTSAWGMSESGLVGLGYGESHRFLAEKVTHLGLLSSPLVLNQIVNWLNIAQQKDKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYC6</accession>
    <name>D0YYC6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transport permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_002289</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell inner membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the ABC-2 integral membrane protein family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299795.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002289"/>
    <dbReference type="EnsemblBacteria" id="EEZ41257">
        <property type="protein sequence ID" value="EEZ41257"/>
        <property type="gene ID" value="VDA_002289"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1552415at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00164">
        <property type="entry name" value="ABC2TRNSPORT"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="24"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="172"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="220"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="253"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="284"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="342"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="365" mass="40444" checksum="17CFCCB1C1BD5039" modified="2010-01-19" version="1">MLQSLYRIKAIMLKEVRQLSRDRITFGMVVMIPLIQLLLFGYAINTDVRNIPVAVVDQSQSVLGREVVQSIKATQVIAVQEHLLTPKQAEQAIVDGRVRAALILPADLANRMENRLTVGQWLVDGSDTMISSALMQLSNMPLPISSHYQSANRKSFDVALFFNPERRSAVNIVPGLLGVILTMTMILFTSAAIVRERERGNLELLITTPVHSLELMVAKIIPYIFVGLIQVVIILGLGYFIFDVPINGGLGQIFIGTLLFIAASLTLGLVISTIAKTQLQAMQMTVFILLPSILLSGFMFPYEGMPVAAQWISEILPATHFMRMIRGIVLRGAEVVDLWRDALWLLGFTCLGLLVASLRFKKSLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYJ2</accession>
    <name>D0YYJ2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NADH dehydrogenase</fullName>
            <ecNumber evidence="4">1.6.99.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_002355</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NADH dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.6.99.3" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299942.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002355"/>
    <dbReference type="EnsemblBacteria" id="EEZ41323">
        <property type="protein sequence ID" value="EEZ41323"/>
        <property type="gene ID" value="VDA_002355"/>
    </dbReference>
    <dbReference type="GeneID" id="57341446"/>
    <dbReference type="eggNOG" id="COG1252">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="403436at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003954">
        <property type="term" value="F:NADH dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006116">
        <property type="term" value="P:NADH oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045024">
        <property type="entry name" value="NDH-2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43706">
        <property type="entry name" value="PTHR43706"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="3">
        <location>
            <begin position="3"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="403" mass="44284" checksum="28AA04A047ADEE42" modified="2010-01-19" version="1">MSRIVIVGGGAAGIELSTLLGRAVRKEDEVILIEPETHHYWKPRLHEIAAGTFDSDLDTVCYFTHGAKHGYQHYQGAMTNIDRNNKQVIVRQPDGAESLVDYDYLVIAVGAVSNDFNTTGARDHCLFLDSAVQARKAWHQISHLLRSGHDHAINIVGAGATGVELAAELARVSQKLQRYKAAKLHINLIEAAPRVLPNCPEKMSDKALKELNRNNINVLVDTRISEVTAEGMTTCDGQTLNADVQFWAAGVKAPDWLRGLGDFTYNRMNQIEVNMNLTTTVDDHIFALGDCAAIPQPDGSFVPPKAQAANRAAVHLAKSLSGMLRGKALTDFVFEDSGMIVAVGHHFAVGALMDGKLVLKGRLIRRLYDTIFRLHQRTVSGVFNVSRLMITKRLKSVFKPASM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYK4</accession>
    <name>D0YYK4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Outer membrane lipoprotein Blc</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_002367</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the calycin superfamily. Lipocalin family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299967.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002367"/>
    <dbReference type="EnsemblBacteria" id="EEZ41335">
        <property type="protein sequence ID" value="EEZ41335"/>
        <property type="gene ID" value="VDA_002367"/>
    </dbReference>
    <dbReference type="GeneID" id="57341433"/>
    <dbReference type="eggNOG" id="COG3040">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1770932at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012674">
        <property type="entry name" value="Calycin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022271">
        <property type="entry name" value="Lipocalin_ApoD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002446">
        <property type="entry name" value="Lipocalin_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022272">
        <property type="entry name" value="Lipocalin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000566">
        <property type="entry name" value="Lipocln_cytosolic_FA-bd_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08212">
        <property type="entry name" value="Lipocalin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036893">
        <property type="entry name" value="Lipocalin_ApoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01171">
        <property type="entry name" value="BCTLIPOCALIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50814">
        <property type="entry name" value="SSF50814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00213">
        <property type="entry name" value="LIPOCALIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="2 4" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipocln_cytosolic_FA-bd_dom" evidence="3">
        <location>
            <begin position="40"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR036893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="196" mass="22630" checksum="0D3C1C5CCEDADBD1" modified="2010-01-19" version="1">MKICHFLPSRNSTIFIPLLVLWLTGCTSVPQQVSPVTAFELNRYMGTWYEIARLDHSFERGLSNISATYHLKRDGSVEVINRGFDVDEKQWSEAIGNAKMVKDIHTGHFKVSFFGPFYSSYVVFHLEPDYSAALVSGYSNDYFWILSRTPSLPKEKINHYLQLAKQHGFATDQLIYPSQIQNRKKVNQMAHLYSTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYX8</accession>
    <name>D0YYX8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hypothetical diadenosine tetraphosphate hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002491</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41459">
        <property type="protein sequence ID" value="EEZ41459"/>
        <property type="gene ID" value="VDA_002491"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0537">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011146">
        <property type="entry name" value="HIT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026026">
        <property type="entry name" value="HIT_Hint"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01230">
        <property type="entry name" value="HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000714">
        <property type="entry name" value="HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="SSF54197"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51084">
        <property type="entry name" value="HIT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HIT" evidence="2">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="108" mass="12242" checksum="953DE88767B10B2E" modified="2010-01-19" version="1">MVPKKDNLREIHHLSEQEQIQLIKESCLIAQLLETDYKAEKINVGALGNLVPQLHLHHIARFSDDIAWPGPIWGNTKGIQRSEAVQQALVEELQSELEQQAEITFIPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ49</accession>
    <name>D0YZ49_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002562</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41530">
        <property type="protein sequence ID" value="EEZ41530"/>
        <property type="gene ID" value="VDA_002562"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5032BEN">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="99" mass="10901" checksum="7CD414FCFDBF7541" modified="2010-01-19" version="1">MEPARILANGQIRWSDGIKEGMHVSPTGSKLTFANYSNEVGAQPVTIFSRIDSARNGDCEYYFDEAKVKRRLEVCKSGEVTLLNQGRVVRVGSLASPII</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ77</accession>
    <name>D0YZ77_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Flagellar biosynthesis protein FlhA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">flhA</name>
        <name evidence="8" type="ORF">VDA_002590</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300413.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002590"/>
    <dbReference type="EnsemblBacteria" id="EEZ41558">
        <property type="protein sequence ID" value="EEZ41558"/>
        <property type="gene ID" value="VDA_002590"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1298">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="436367at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044780">
        <property type="term" value="P:bacterial-type flagellum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.540">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042194">
        <property type="entry name" value="FHIPEP_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042193">
        <property type="entry name" value="FHIPEP_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042196">
        <property type="entry name" value="FHIPEP_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025505">
        <property type="entry name" value="FHIPEP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006301">
        <property type="entry name" value="FlhA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001712">
        <property type="entry name" value="T3SS_FHIPEP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30161">
        <property type="entry name" value="PTHR30161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00771">
        <property type="entry name" value="FHIPEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005419">
        <property type="entry name" value="FlhA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00949">
        <property type="entry name" value="TYPE3IMAPROT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01398">
        <property type="entry name" value="FlhA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00994">
        <property type="entry name" value="FHIPEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1005">Bacterial flagellum biogenesis</keyword>
    <keyword evidence="7" id="KW-1006">Bacterial flagellum protein export</keyword>
    <keyword evidence="3 7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0966">Cell projection</keyword>
    <keyword evidence="8" id="KW-0969">Cilium</keyword>
    <keyword evidence="8" id="KW-0282">Flagellum</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="46"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="71"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="123"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="209"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="241"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="280"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ41558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="701" mass="75967" checksum="F3DA7A7594A320E1" modified="2010-01-19" version="1">MKLSVPFTNKLPFDRLQSMPAIGAPVLVLATLAMVVLPMPPLLLDMAFTFNIALALVVLLVTIYTRRPLDFAAFPTVLLIATLLRLALNVASTRVVLLHGHEGSDAAGQVIDAFGSVVIGGNYAVGLVVFVILMIINFMVVTKGAGRISEVSARFTLDAMPGKQMAIDADLNAGLIDQEQARTRRAEVTKEADFYGSMDGASKFVKGDAIAGILILFINIIGGLIIGMMQHQLGFAEAASIYSLLTIGDGLVAQIPSLLLSIAAAMMVTRQNTDEDMGKALYFQMFNNPQALMITGVILFVMGIVPGMPHIPFLLLALLIGAVAYWRITKEKQAIENNQSSSSSLPAELTPQQAPKELSWDDVQPVDMIGLEVGYRLISMVDKEQGGELLERIKGVRKKLSQDFGFLIPAVHIRDNLELPPNCYRISLMGVTCGEANIHPNMELAINPGQVYGNIDGEMTKDPAFGLDAVWVQESQREHAQALGYTVVDSSTVLATHLSQILTNNAAHLLGHEEVQNLLEMLGQSTPKLVDGFVPDQLPLGVVVKVMQNLLNEAIPLRDIRTIVQTLSEYSSKSQDPDILTAAVRIGLKRLICQDINGVEAELPVITLVPELEQILHKTMQSAGGESTGIEPGLAERLQQSLADATQQQEFKGEPAVLLTSGVLRSTLAKFVKNTIPTLRVLSYQEVPDEKQIRIVNAVGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ92</accession>
    <name>D0YZ92_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Flagellar hook-associated protein 2</fullName>
            <shortName evidence="5">HAP2</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Flagellar cap protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_002605</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 5">Homopentamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Secreted</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Bacterial flagellum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the FliD family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300462.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002605"/>
    <dbReference type="EnsemblBacteria" id="EEZ41573">
        <property type="protein sequence ID" value="EEZ41573"/>
        <property type="gene ID" value="VDA_002605"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1345">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="883503at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009421">
        <property type="term" value="C:bacterial-type flagellum filament cap"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009424">
        <property type="term" value="C:bacterial-type flagellum hook"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010810">
        <property type="entry name" value="Flagellin_hook_IN_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040026">
        <property type="entry name" value="FliD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010809">
        <property type="entry name" value="FliD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003481">
        <property type="entry name" value="FliD_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30288">
        <property type="entry name" value="PTHR30288"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07196">
        <property type="entry name" value="Flagellin_IN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07195">
        <property type="entry name" value="FliD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02465">
        <property type="entry name" value="FliD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="8" id="KW-0966">Cell projection</keyword>
    <keyword evidence="8" id="KW-0969">Cilium</keyword>
    <keyword evidence="3 5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0282">Flagellum</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="FliD_N" evidence="6">
        <location>
            <begin position="10"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="FliD_C" evidence="7">
        <location>
            <begin position="224"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="406"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ41573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="462" mass="50422" checksum="3407F67A7FD8861A" modified="2010-01-19" version="1">MGLSAGGLASGLDITGMTQQLVAAERAPKEQRIKEQQQKVGVQLSGYGQIKSAVSGLEDMVKKFTEDKVFAGQSAESSESSFVDVKASAEAKNGTYNIEVLALAKSHKIVSNNAFDSDPKAELGSGTLDITVDGKTMSLTIDKNKSSLKEVVSAINNASDNPGVTATVINDEKGAKIVFSSSQTGVKNQISIDASKMDGELKKLSFDPSNITANPEMIQMQAGVDAQIRIDNHTVVSNDSNKFEDVIEGLTLDIKKLTNTEDVKSAKIDITNNTSGAKKAIKEFIDAYNGFIDTSESLSKYNTETKSSGPLNGDSLTRSIISQMRNLMNSGVEVNNQSYYLSDFGVTTDRYGKIEIDDEKLDDALKDNFKAFNAFFHTKDDGFLDKSEAIFKSFTSSTDGSITQKEKSLKEQQQRLNDDMSDLNERMKAYEERTYKQFSAMDAAIGKMNNELNTMMSLMVFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZB7</accession>
    <name>D0YZB7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">N-acetylglucosamine-regulated outer membrane porin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002630</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300542.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002630"/>
    <dbReference type="EnsemblBacteria" id="EEZ41598">
        <property type="protein sequence ID" value="EEZ41598"/>
        <property type="gene ID" value="VDA_002630"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502Z7J2">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="200714at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005318">
        <property type="entry name" value="OM_porin_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34596">
        <property type="entry name" value="PTHR34596"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019864" evidence="2">
        <location>
            <begin position="27"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="470" mass="51567" checksum="DE74A4C029985D51" modified="2010-01-19" version="1">MEAKFFKVSALTAAMVGAFVAMPVMATSDSAAGPEYVEAVNEFIDGSTLAGVAVVDTRSRTRTTGKPGGQDGDRWSRLNYSSYNLILDFTSGYHDGWLGADLGGYFSGDLYNDSAVNGGTGEYLCNEISTCNNLDWGAGDGQQFKVTRAALKFKAGEAVDGRFGFTQANGNGVLGNVWSFVPGTYRGAELNANLDRFKLTYFIADQFTAPWLLSENDYAPALWSDTSWSMVHSLGFSGNVSDQLFIQLGLGQATDVRYANSIDWGAGVVNSYHGETDTTGYKAYAKYTFNENMSLAYDFYGVNDDVQYDGLGFTTGLSFNAKFGQFSWMSDLQYASSNNDRDVNPRMIYTYGMTNGTYSLWWDALSDWNKSGEVAWYNRISYDQGNGWNYYLGFGYGTGSKSAAEGAKGDWDYESEYAFNATIAYSLQSGALKGSTIRLHGTVLERDEYAGAPKADETDLRFQVIIPYTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZL5</accession>
    <name>D0YZL5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">YadA_anchor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_002728</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell surface</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002728"/>
    <dbReference type="EnsemblBacteria" id="EEZ41696">
        <property type="protein sequence ID" value="EEZ41696"/>
        <property type="gene ID" value="VDA_002728"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3266">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005594">
        <property type="entry name" value="YadA_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03895">
        <property type="entry name" value="YadA_anchor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019866" description="YadA_anchor domain-containing protein" evidence="7">
        <location>
            <begin position="21"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="YadA_anchor" evidence="8">
        <location>
            <begin position="193"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="21"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="48"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="254" mass="27017" checksum="BA467E4A3870D1E3" modified="2010-01-19" version="1">MKKTTIALSLSMLMSSMAIAATPSNPIEQPKPSHPIENVRPTQPIEAAPSNPIEPPKPTHPIENVRPTQPIEAAPSNPIEPPKPTHPIENEKPSQPIEAAPENPIENTKPSKPIEAAPENPIEVPATPEQPIVADPDFGVTPKSNDTVRIDNLEKSFQSFAEETQRKFSELDEQMDGVRAGLHAVTNARPYVANGQFAVGAGVGFAGSKEALALGGAYGINENLSVSGTFHYETSGKYSSSEVAGGVGLQYSFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZM8</accession>
    <name>D0YZM8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Recombination-associated protein RdgC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rdgC</name>
        <name evidence="6" type="ORF">VDA_002741</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 5">May be involved in recombination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 5">Cytoplasm</location>
            <location evidence="2 5">Nucleoid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the RdgC family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300878.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002741"/>
    <dbReference type="EnsemblBacteria" id="EEZ41709">
        <property type="protein sequence ID" value="EEZ41709"/>
        <property type="gene ID" value="VDA_002741"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2974">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="655073at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009295">
        <property type="term" value="C:nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00194">
        <property type="entry name" value="RdgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007476">
        <property type="entry name" value="RdgC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38103">
        <property type="entry name" value="PTHR38103"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04381">
        <property type="entry name" value="RdgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="304" mass="34586" checksum="02AA424CF9444480" modified="2010-01-19" version="1">MMWFKNLLTYRFTREIDLNADQLEKQLEEFRFTPCGSQDIQKFGWAHALGKHGDMFTHVSGDNILICARKEEKMLPASVIKESLNNKIEMQEKDLGRKLKKTEKDTLKDEIVMDLLPRAFSRKSQTYALIMPKLGFIIVDAGSFKKAEDMLALLRKSIGSLPVVPVVAEKPLALTMTEWIRSNQAPHGFTMGEEAEFKAVEEDGGVIRCKQQDLNCDEILAHIEANKVVTKLAMNWQDRIDFVLADDLTVKRLKFSDELKDQNEDIDREDIAQRIDADLSLMGGEFSAFLPNLFEEVGGLENKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZP4</accession>
    <name>D0YZP4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002757</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002757"/>
    <dbReference type="EnsemblBacteria" id="EEZ41725">
        <property type="protein sequence ID" value="EEZ41725"/>
        <property type="gene ID" value="VDA_002757"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3156">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="413" mass="46255" checksum="B8A3BBAD1BDE9D7C" modified="2010-01-19" version="1">MNRYYQQGMSTLLITSMLLVVALIFSLASYKNLFYQIKRTQNEVLARQAHWAAEGGLECGFAKVQKVGSISDARASFPDCEHELDLADVDINSDNIIVSYYNKLAVKKIEKEIFLLPESYGAIQSRSDLKFLGDVKIAPDVIDHISGNNYRCISIKYSSKVESLDRLKILKPGEGHYNVTFSYPNVSSSAICNNEYNTDASNFDTNITPPSSNGPVKKDFEYDPFFDPFEGFFNKKRSEIASIKSEFKVINGSIDSITSDNRCAEKINKAFAISNKVWVKGDCDLHGDLIGSNPTIINQAKVLVFENGIVGTVGSTTFNGSVYHLIDEPDFYNVSLIPRWEAMSSSSFYAHLLDTNSVFFSFGSFVPTGGIIFDTPKGVTTYSSSLNLTYNRNFNPYVPKYKPNWKKGSWHDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZY9</accession>
    <name>D0YZY9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">30S ribosomal protein S20</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rpsT</name>
        <name evidence="10" type="ORF">VDA_002852</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">Binds directly to 16S ribosomal RNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the bacterial ribosomal protein bS20 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301197.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002852"/>
    <dbReference type="EnsemblBacteria" id="EEZ41820">
        <property type="protein sequence ID" value="EEZ41820"/>
        <property type="gene ID" value="VDA_002852"/>
    </dbReference>
    <dbReference type="GeneID" id="57340861"/>
    <dbReference type="eggNOG" id="COG0268">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2005443at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00500">
        <property type="entry name" value="Ribosomal_S20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002583">
        <property type="entry name" value="Ribosomal_S20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036510">
        <property type="entry name" value="Ribosomal_S20_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33398">
        <property type="entry name" value="PTHR33398"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01649">
        <property type="entry name" value="Ribosomal_S20p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46992">
        <property type="entry name" value="SSF46992"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00029">
        <property type="entry name" value="S20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6 8 10" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 8" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="11"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ41820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="86" mass="9677" checksum="EFA900169D75B3D8" modified="2010-01-19" version="1">MANIKSAKKRALTSEKRRKHNASRRSMMRTFFKKVVAAIEAGNKEAATQAFVEMQPVMDRMATKGLIHKNKAARHKARLAAKIKAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z011</accession>
    <name>D0Z011_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Sodium/alanine symporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_002874</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell inner membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301256.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002874"/>
    <dbReference type="EnsemblBacteria" id="EEZ41842">
        <property type="protein sequence ID" value="EEZ41842"/>
        <property type="gene ID" value="VDA_002874"/>
    </dbReference>
    <dbReference type="GeneID" id="57340836"/>
    <dbReference type="eggNOG" id="COG1115">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="883596at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015655">
        <property type="term" value="F:alanine:sodium symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001463">
        <property type="entry name" value="Na/Ala_symport"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30330">
        <property type="entry name" value="PTHR30330"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01235">
        <property type="entry name" value="Na_Ala_symp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00175">
        <property type="entry name" value="NAALASMPORT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00835">
        <property type="entry name" value="agcS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00873">
        <property type="entry name" value="NA_ALANINE_SYMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0769">Symport</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="93"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="178"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="206"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="233"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="301"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="347"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="391"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="418"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="475" mass="51259" checksum="0A417C07EA14EFBB" modified="2010-01-19" version="1">MTSQINFLNDLLWGSVLIYILIGVGIYFTYRLGFIQFRHFGHMFQVMKNSRKSDPSGISSFQALCTSLAARVGTGNMAGVAVALTLGGPGAVFWMWLIAMLGMATAFAESTLAQLYKTRDDDGNYRGGPAYYMEKGLGMRWMGIVFSIFLIIAFGLVFNSVQANSITQAMHVAFGWNPLYVGLVLVVMTGVIIFGGLRAIARTAEILVPAMALCYLAIALFIMFANIEKLPDVIMMIISNAFGFGEAASGALGYTIAQGMINGLKRGLFSNEAGMGSAPNAAASATPYPPHPASQGYVQMLGVFMDTIVICSATVAIILMSGEYVPHGDVTGIQLTQQALSSQVGDWGAIFIAVAIFFFAFTSLVANYSYAETNLIFLEHNHKMGLNIFRVVVLGMVMFGALADLPTVWAMADVSMGMMALINLVAIVLLSGTVVKLAKDYNHQLAQGKVPTFDSNDYPELHAQLEEGIWDQSKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z048</accession>
    <name>D0Z048_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glucosamine kinase GpsK</fullName>
            <ecNumber evidence="2">2.7.1.8</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002911</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.1.8" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301325.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002911"/>
    <dbReference type="EnsemblBacteria" id="EEZ41879">
        <property type="protein sequence ID" value="EEZ41879"/>
        <property type="gene ID" value="VDA_002911"/>
    </dbReference>
    <dbReference type="GeneID" id="57340797"/>
    <dbReference type="eggNOG" id="COG2971">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1589192at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047931">
        <property type="term" value="F:glucosamine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002731">
        <property type="entry name" value="ATPase_BadF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01869">
        <property type="entry name" value="BcrAD_BadFG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="BcrAD_BadFG" evidence="1">
        <location>
            <begin position="8"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="297" mass="31427" checksum="A083FBD228412197" modified="2010-01-19" version="1">MTEIRYFVGIDGGGTSCRARIVDRNGNVLGEAKTGSANILLGADVAMKSIQDAIATAASLAQLSDSDFAFMSVGLALAGAEQKEAWYHFMSQPHPYAAITLNTDAYGACLGAWAGKDGAILIAGTGSCGIFLHQGQQIVVGGREFPISDQGGGAIMGLRLIQQVLLSVDGIVAQTPLAKEILAHFDQDIDAIVSWSKTARPCDYGQFSPQIFAYANQGDSLGISLLNQTAADIEMWMQALINKGANKICLMGSIAERIQPWLVPPMQQHIAKPQGDAMDGAIAMAQGNHNLYALEDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z079</accession>
    <name>D0Z079_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Adenylate cyclase</fullName>
            <ecNumber evidence="3">4.6.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002942</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="4.6.1.1" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301392.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002942"/>
    <dbReference type="EnsemblBacteria" id="EEZ41910">
        <property type="protein sequence ID" value="EEZ41910"/>
        <property type="gene ID" value="VDA_002942"/>
    </dbReference>
    <dbReference type="GeneID" id="57340751"/>
    <dbReference type="eggNOG" id="COG3025">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1878295at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050355">
        <property type="term" value="F:triphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.40.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007899">
        <property type="entry name" value="CHAD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038186">
        <property type="entry name" value="CHAD_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033469">
        <property type="entry name" value="CYTH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023577">
        <property type="entry name" value="CYTH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039013">
        <property type="entry name" value="YgiF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39569">
        <property type="entry name" value="PTHR39569"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01928">
        <property type="entry name" value="CYTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00880">
        <property type="entry name" value="CHAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01118">
        <property type="entry name" value="CYTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55154">
        <property type="entry name" value="SSF55154"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51708">
        <property type="entry name" value="CHAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51707">
        <property type="entry name" value="CYTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CYTH" evidence="1">
        <location>
            <begin position="2"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="CHAD" evidence="2">
        <location>
            <begin position="219"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="504" mass="58430" checksum="6105D12CC12931C8" modified="2010-01-19" version="1">METEIELKFFVFPEFSTQLLTKISEMKILQQSSRLLGNVYFDTPDQQLRQHDIGLRVRRFDDVFVQTLKTAGRVVAGLHQRPEYNVEITGQEPDLSLHPQDAWPEGLDIAALQQQLCPLFSTDFERQQWLVAMADGSQIEVAFDQGQVSANGKSEPICEVELELKSGQTDALFTLARELCAQGGMRLGNLSKAARGYRLATDYTGDEVKALGLVPASNNESVEQVFVRSLEHALEHWLYHEQIYVERQEQAALIQITQAISLLRQILVVFGSMIPRRASALLRQELQWLEGELDWVEEAENIQDLLSERGYQLKKLNARKQIMQLLEARYDELPERDDMLRLLQSGRYCGLLLNLSSWILSHAWQPFLDDKSREKLASSAKTFSDGFLTRSWQELQDVFPLERQLSRLDYLDQQPRLLRNLMSGVCFANLYDEERRNNFRLPWLDLLQGVEDLRELEPIRQICPQFSDDDLQQIEKWLERKDESLLHAMDQTRQMGIELTPYWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0A9</accession>
    <name>D0Z0A9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pseudouridine synthase</fullName>
            <ecNumber evidence="3">5.4.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_002972</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Responsible for synthesis of pseudouridine from uracil.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a uridine in RNA = a pseudouridine in RNA</text>
            <dbReference type="Rhea" id="RHEA:48348"/>
            <dbReference type="Rhea" id="RHEA-COMP:12068"/>
            <dbReference type="Rhea" id="RHEA-COMP:12069"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pseudouridine synthase RluA family.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002972"/>
    <dbReference type="EnsemblBacteria" id="EEZ41940">
        <property type="protein sequence ID" value="EEZ41940"/>
        <property type="gene ID" value="VDA_002972"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0564">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140098">
        <property type="term" value="F:catalytic activity, acting on RNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034470">
        <property type="term" value="P:ncRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02869">
        <property type="entry name" value="PseudoU_synth_RluA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006225">
        <property type="entry name" value="PsdUridine_synth_RluC/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006224">
        <property type="entry name" value="PsdUridine_synth_RluC/D_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00005">
        <property type="entry name" value="rluA_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01129">
        <property type="entry name" value="PSI_RLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PseudoU_synth_2" evidence="4">
        <location>
            <begin position="35"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR606225-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="241" mass="28015" checksum="8223373C0F1CD63B" modified="2010-01-19" version="1">MIYRIHFESAMKPLPLLDYNPPQDPWLDVLHLDRDIIAVNKPSGLLSVPGRDPAHYDSIYSRVLRDHPKSQIVHRLDMTTSGLIVLAINKNAERHLKAQFRERQTHKVYYARVWGHLEQQHGSVDLPLICDWPNRPKQKVCYEEGKPSLTHYEVVRYEENATLVRLLPVTGRSHQLRVHMMAIGHPILGDRFYAHDEAREMAPRLQLHAAELTFAHPYTEEPMHIFAPCDFYPDAPTRTLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0B0</accession>
    <name>D0Z0B0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DnaJ-like protein DjlA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_002973</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002973"/>
    <dbReference type="EnsemblBacteria" id="EEZ41941">
        <property type="protein sequence ID" value="EEZ41941"/>
        <property type="gene ID" value="VDA_002973"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1076">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3680.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007791">
        <property type="entry name" value="DjlA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029024">
        <property type="entry name" value="TerB-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05099">
        <property type="entry name" value="TerB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="SSF46565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="3">
        <location>
            <begin position="122"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="188" mass="21489" checksum="234A74097F5A1A93" modified="2010-01-19" version="1">MDRMGLQGEARRRAQDAFRQGKNEQFPLEETLLKVRQARRADLSRFFLELQIAAAFADGSIHPNERQMLHVIARHLGFSEAQLEQTLRMQEAAFRFQQGGFNQQYQNAGGFQQAPTRDQLADAYNVLGVDESASAQEVKRAYRKLMSEHHPDKLAAKGLPPEMMEIAKQKAQELQAAYDLIRKEKGFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0K3</accession>
    <name>D0Z0K3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Predicted symporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_003067</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301741.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003067"/>
    <dbReference type="EnsemblBacteria" id="EEZ42034">
        <property type="protein sequence ID" value="EEZ42034"/>
        <property type="gene ID" value="VDA_003067"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4147">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="278483at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018212">
        <property type="entry name" value="Na/solute_symporter_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019899">
        <property type="entry name" value="Na/solute_symporter_VC_2705"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
        <property type="entry name" value="SSF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03648">
        <property type="entry name" value="Na_symport_lg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00457">
        <property type="entry name" value="NA_SOLUT_SYMP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0915">Sodium</keyword>
    <keyword evidence="7" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="4" id="KW-0769">Symport</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="77"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="116"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="146"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="179"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="247"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="281"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="377"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="424"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="449"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="481"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="522"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ42034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="567" mass="60833" checksum="5B3AEBE06C920991" modified="2010-01-19" version="1">MDIQTWTFIIVGITFAVYIGIAIWSRAGSTSEFYVAGGGVHPVANGMATAADWMSAASFISMAGIISFIGYDGGVYLMGWTGGYVLLALCLAPYLRKFGKFTVPDFIGDRYYSKTARMVAVFCAIFVSFTYVAGQMRGVGVVFARFLEVDINMGIMIGMGIVFFYAVMGGMKGITYTQVAQYCVLIFAFMVPAIFTSLMITGSPIPQIGFGSTINGSETYLLEKLDGITQELGFTAYTDGSKSIVDVFFICAALMVGTAGLPHVIIRFFTVPKVKDARISAGWALIFIAILYTTAPAVAAFARINLIDTINGPDMKGVSAEQAPSWVTNWEKTGLVSWQDKNGDGKMFYSGDDRNEMTINRDIIVLASPELAKLPNWVVALLAAGGLAAALSTAAGLLLVISTSISHDLLKKGFKPNMTDKQELLAARLGAIVAIVGAGYLGINPPGFVAQVVAFSFGLAASSFFPAIILGIFYKRMNKEGAISGMIAGIAFTTAYIIYFKFINPAANTPENWWFGISPEGIGTLGMCLNFVVAIVVNKFTAEVPNDVQEMVESIRYPQGAGEAHDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-06-02" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0K4</accession>
    <name>D0Z0K4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Histidine kinase</fullName>
            <ecNumber evidence="4">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">VDA_003068</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301743.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003068"/>
    <dbReference type="EnsemblBacteria" id="EEZ42035">
        <property type="protein sequence ID" value="EEZ42035"/>
        <property type="gene ID" value="VDA_003068"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0591">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0784">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004721">
        <property type="term" value="F:phosphoprotein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="16" id="KW-0418">Kinase</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 11" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="16" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="69"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="113"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="161"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="190"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="237"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="278"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="321"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="375"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="404"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="435"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="14">
        <location>
            <begin position="798"/>
            <end position="1009"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="15">
        <location>
            <begin position="1032"/>
            <end position="1148"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="746"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="11">
        <location>
            <position position="1082"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EEZ42035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="1160" mass="128371" checksum="92942B8F91533BC6" modified="2010-01-19" version="1">MSQGWVVTLISLGYLIVLFGIAWYGDKKRQWLARWRPWIYSLSIAVYCTSWTFYGTVGQASDDTWSFVPIYLAPILVFVFAWRVLARIILIAKREHITSIADFIAARYGKSQALAVAVTLIALLGILPYIALQLRGIALGVEQIAPQLSQTLVQKWGRVDFMFMLTLLLALFTIVFGSRHIDTTEHHRGLMLAVAFESLLKLVAFLLLAGFAVFWLIQPPVSSTILSMSSFSWQAPNWPTFAIHTLLAMTAIICLPRQFHTIVVENQQPKDLHLARKVFPLYLLLMGLGVLPIAILGQQLLPTVSADTLIINLPLYLQHNWLAILTFLGGTSAAAGMVIVSTIALAIMLSNDLVLPLLLRRLPIPQRSFKAFSQVLLKIRRLLIGLVLLAAWGVALALESISSLATIGLLAFAAMAQFAPALIGGIYWRKGNRNGVFCGLAVGITLWLLTLMQQADLLAGNGETNVVLWLLTPPPTLLAAEVSITDWGMFLSLLANLLCYVVVSLLSRASLTERLQAASFVGVPVPEQDSGRLYQTRVTVAELEMLVARFVGRKRTRQAFAQYSQQHQPLVSSQLASANLIRHTERMLAGVFGTSTARLVLSSALEGRNMQLEEVATIVDEASELFDFSRGLLQGAIEHISQGIAVVDKKLYLVAWNQRYLELFHFPAGLIQVGRPIEDVIRHNAQMGLCGPGDPEWHVAKRVEHLKRGTAHTSSRIRPDGQVIEVQGNPMPGGGFVMSFTDITAFRQAEGALQEANENLEARVQQRTQQLEQLNRRLVVATQQAERQAHSKSRFLAAVSHDLMQPLNAAKLFSSSLAEVAQDPESQQLARHIESSLEAAEDLISDLLDISRLEAGKLNTQVHAFALSDVLNTLNAEFNALAQQQGTQFSLINTQAMIYSDPKLLRRALQNFLTNALRYNPGGKVLLGVRRKRDDLLIEVWDNGPGIEASKQAQIFDEFTRFDQDIKGQGLGLGLAIAKGIARVLNHSLDLRSWPGKGTVFSLQVSRATVAQAKPIARTTSQEMSHSLQGLRVLCVDNEAPILAAMKGVLSRWQCDVRLAPDLFSALQHITPQWQPQVILTDFHLDRGQTGLEVLQQCRLRLGQEFAGVVISADRTTAIQERVKTQGFAYLSKPVKPLKLRALLNQITQQQKKQRLSEPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0N5</accession>
    <name>D0Z0N5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7 8">Elongation factor Tu</fullName>
            <shortName evidence="7">EF-Tu</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">tuf</name>
        <name evidence="10" type="ORF">VDA_003099</name>
        <name evidence="11" type="ORF">VDA_003437</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301856.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003099"/>
    <dbReference type="EnsemblBacteria" id="EEZ42066">
        <property type="protein sequence ID" value="EEZ42066"/>
        <property type="gene ID" value="VDA_003099"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ42404">
        <property type="protein sequence ID" value="EEZ42404"/>
        <property type="gene ID" value="VDA_003437"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0050">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="621774at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01884">
        <property type="entry name" value="EF_Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03697">
        <property type="entry name" value="EFTU_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00118_B">
        <property type="entry name" value="EF_Tu_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041709">
        <property type="entry name" value="EF-Tu_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033720">
        <property type="entry name" value="EFTU_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004541">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_bac/org"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004160">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03143">
        <property type="entry name" value="GTP_EFTU_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="SSF50465"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00485">
        <property type="entry name" value="EF-Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 7 10" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="5 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="9">
        <location>
            <begin position="10"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="19"/>
            <end position="26"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="81"/>
            <end position="85"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="136"/>
            <end position="139"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ42066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ42404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="394" mass="43010" checksum="62A57F0401D48DC5" modified="2010-01-19" version="1">MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAICTVLSKVYGGSARDFASIDNAPEERERGITISTSHVEYDTPTRHYAHVDCPGHADYVKNMITGAAQMDGGILVVAATDGPMPQTREHILLGRQVGIPYIIVFMNKCDMVDDEELLELVEMEVRELLSEYDFPGDDCPVIMGSALGALNGEEQWEAKVVELAEALDNYIPEPERAIDKPFILPIEDVFSIQGRGTVVTGRVEQGIITVGDEVEIVGIKPTTKTTCTGVEMFRKLLDEGRAGENVGVLLRGTKRDEVERGQVLAKPGSITPHTTFTSEIYVLSKDEGGRHTPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNISMTVTLIAPIAMDEGLRFAIREGGRTVGAGVVATIIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0P7</accession>
    <name>D0Z0P7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Unsaturated fatty acid biosythesis repressor FabR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_003111</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301890.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003111"/>
    <dbReference type="EnsemblBacteria" id="EEZ42078">
        <property type="protein sequence ID" value="EEZ42078"/>
        <property type="gene ID" value="VDA_003111"/>
    </dbReference>
    <dbReference type="GeneID" id="57340664"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023772">
        <property type="entry name" value="DNA-bd_HTH_TetR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01081">
        <property type="entry name" value="HTH_TETR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="10"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ42078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="210" mass="23929" checksum="840EC632C0143F20" modified="2010-01-19" version="1">MGIRAQQKEKTRRALIDAAFGQLSADRSFSSLSLREVAREAGIAPTSFYRHFKDMDELGLTMVDEGGLILRQLMRQARQRIATEGSVIRTSVETFMEFIESSPNVFRLLLRERSGTSTAFRAAVAREIQHFVAELTEYLEAKTGVTHEEAFTQAEASVTLVFSSGAEALDLDSHARAEHAERLIMQLRMIAKGAYWYRKERERRELRQKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z133</accession>
    <name>D0Z133_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9 10">Chromosomal replication initiator protein DnaA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">dnaA</name>
        <name evidence="14" type="ORF">VDA_003247</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 11">Belongs to the DnaA family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302278.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003247"/>
    <dbReference type="EnsemblBacteria" id="EEZ42214">
        <property type="protein sequence ID" value="EEZ42214"/>
        <property type="gene ID" value="VDA_003247"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0593">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="219876at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006275">
        <property type="term" value="P:regulation of DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06571">
        <property type="entry name" value="Bac_DnaA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1750.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00377">
        <property type="entry name" value="DnaA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001957">
        <property type="entry name" value="Chromosome_initiator_DnaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020591">
        <property type="entry name" value="Chromosome_initiator_DnaA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018312">
        <property type="entry name" value="Chromosome_initiator_DnaA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013317">
        <property type="entry name" value="DnaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013159">
        <property type="entry name" value="DnaA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024633">
        <property type="entry name" value="DnaA_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038454">
        <property type="entry name" value="DnaA_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010921">
        <property type="entry name" value="Trp_repressor/repl_initiator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30050:SF2">
        <property type="entry name" value="PTHR30050:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00308">
        <property type="entry name" value="Bac_DnaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08299">
        <property type="entry name" value="Bac_DnaA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11638">
        <property type="entry name" value="DnaA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00051">
        <property type="entry name" value="DNAA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00760">
        <property type="entry name" value="Bac_DnaA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48295">
        <property type="entry name" value="SSF48295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00362">
        <property type="entry name" value="DnaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01008">
        <property type="entry name" value="DNAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9 10" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 9 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="12">
        <location>
            <begin position="171"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="domain" description="Bac_DnaA_C" evidence="13">
        <location>
            <begin position="382"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="179"/>
            <end position="186"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEZ42214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="474" mass="53302" checksum="40471394F1574166" modified="2010-01-19" version="1">MSSSLWLQCLQRLQEELPATEFSMWVRPLQAELNDNTLTLFAPNRFVLDWVRDKYLNNINRLLNEFCGQDVPILRFEVGSKPISAPSITPAPAPILTPTPIPVVTPAPAPIEAAVMPADILPAVAHPAAQQAGGCRSNVNPKHNFNNFVEGKSNQLGLAACRQVADNPGAAYNPLFLYGGTGLGKTHLLHAVGNAIADRKPNAKVVYMHSERFVQDMVKALQNNAIEEFKRYYRSVDALLIDDIQFFANKERSQEEFFHTFNALLEGNQQIILTSDRYPREINGVEDRLKSRFGWGLTVAIEPPELETRVAILMKKAEDHNIRLADEVAFFIAKRLRSNVRELEGALNRVIANANFTGRAITIDFVREALRDLLALQEKLVTIDNIQKTVAEYYKIKMADMLSKRRSRSVARPRQMAMALAKELTNHSLPEIGDAFGGRDHTTVLHACRKIEQLREESHDIKEDYSNLIRTLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z134</accession>
    <name>D0Z134_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Beta sliding clamp</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">VDA_003248</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Forms a ring-shaped head-to-tail homodimer around DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the beta sliding clamp family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302281.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003248"/>
    <dbReference type="EnsemblBacteria" id="EEZ42215">
        <property type="protein sequence ID" value="EEZ42215"/>
        <property type="gene ID" value="VDA_003248"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0592">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1040142at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009360">
        <property type="term" value="C:DNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00140">
        <property type="entry name" value="beta_clamp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001001">
        <property type="entry name" value="DNA_polIII_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022635">
        <property type="entry name" value="DNA_polIII_beta_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022637">
        <property type="entry name" value="DNA_polIII_beta_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022634">
        <property type="entry name" value="DNA_polIII_beta_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30478">
        <property type="entry name" value="PTHR30478"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00712">
        <property type="entry name" value="DNA_pol3_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02767">
        <property type="entry name" value="DNA_pol3_beta_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02768">
        <property type="entry name" value="DNA_pol3_beta_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000804">
        <property type="entry name" value="DNA_pol_III_b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00480">
        <property type="entry name" value="POL3Bc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00663">
        <property type="entry name" value="dnan"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 10" id="KW-0235">DNA replication</keyword>
    <keyword evidence="9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8 10" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="6 10 14" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA_pol3_beta" evidence="11">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="DNA_pol3_beta_2" evidence="12">
        <location>
            <begin position="128"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="DNA_pol3_beta_3" evidence="13">
        <location>
            <begin position="244"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR000804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEZ42215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="365" mass="40529" checksum="C7CA20CBC3DA6B1D" modified="2010-01-19" version="1">MKFTLAREQLLKPLQQVSGALGRPSLPILGNILLQVEEGLLSLTGTDLEVELVAKIVLEGEFEAGAITVPSRKFLDICRGLPDSATISVSVEGDRALIRSGRSRYSLATLPASDFPNIDDWQSEVEFELEQSRLRQLIDSTQFSMAHQDVRYYLNGMLFETDGKLLRTVATDGHRMAVCAIDTAYDVPSKQIILPRKGVLELVRLLDNPEAPVQIQIGGSNLRATVNNFVFTSKLVDGRFPDYRRVLPQNSNKFVTASCDELRKAFSRAAILSNEKFRGVRVNLAAGEMRITANNPEQEEAEEFLDVDYQGEPIEIGFNVSYVLDVLNTLKCEQVKMSLTDANASALLEDNAVDDAMYVVMPIRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z151</accession>
    <name>D0Z151_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RND multidrug efflux transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_003265</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302330.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003265"/>
    <dbReference type="EnsemblBacteria" id="EEZ42232">
        <property type="protein sequence ID" value="EEZ42232"/>
        <property type="gene ID" value="VDA_003265"/>
    </dbReference>
    <dbReference type="GeneID" id="57340309"/>
    <dbReference type="eggNOG" id="COG0841">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="145346at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="333"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="359"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="385"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="430"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="462"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="522"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="847"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="874"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="900"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="945"/>
            <end position="966"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="978"/>
            <end position="1004"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ42232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="1039" mass="112510" checksum="357711F80DD69DA6" modified="2010-01-19" version="1">MRFTDVFIKRPVLAVSISFLIALLGLQAVFKMQVREYPDMTNTVVTVSTGYYGASADLIQGFITQPLEQAIAQADNIDYMTSSSVLGSSTITVNMKLNTDPNAALADILAKTNSVRSQLPKEAEDPTVTMSTGSGTAVMYIGFTSDELSSSQITDYLQRVVTPQLFTVNGVSKVDLYGGMKYALRVWLDPAKMGAYNLSAADVMNVLNSNNYQSATGQATGEFVLYNGSADTQVKNTDELKKLVVSTQKGQVIRLGDIAKVTLAKSHDQYRATANGQEAVVAAINAAPTANPINIAKGIYQILPELERNMPSTIKMNIMYDSTIAINESIHEVIKTIVEAAVIVLVVITLFLGSIRAVVIPVVTIPLSLIGVAMVMQALGFSWNLLTLLAMVLAIGLVVDDAIVVLENVDRHIKEGESPFRAAIIGTREIAVPVIAMTLTLGAVYAPIALMGGLTGTLFKEFALTLAGTVFISGIVALTLSPMMCSKMLKADKTPSKFEQVVHNTLERITVRYEKILHGLMTMRPVVIGFAVLVFVSLPLMFKFIPSELAPAEDNGVVVLMANAPSNVNLDYIQNTMDQVNHVLTDQPEVAFSMIFSGVMTSNQAFGIASLVPWSERKASQAQIAKRVTGLVKDVPQMAVTAFQMPPLPGAGSGLPMQFVITTPNNFESLFQVASTFLTKVKENPQIVYSDLDLNFDSATMKIKIDKDKAGAYGITMQNIGQTLSTMMADGYVNRIDLNGRSYEVIPQVERKYRLNPENLKNYYVRAANGDSIPLSSLVTISVISEPRSLPTFNQLNSATISAALAPGVAMGDAINWFESTAQTVLPSGYQYNFMGEARQFVTEGNALYFTFLLALAIIFLVLAIQFESLRDPLVILITVPLAICGALISLAWGAATMNIYSQVGLITLIGLISKHGILICEVAKEEQLNNKKSRMDAVIEAARIRLRPILMTTAAMIAGLIPLLYASGAGAASRFSIGIVIVAGLSVGTLFTLFVLPVIYTYLASIHKPLPVFVEDKDLEKLKRVDEARNALKNRDDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z160</accession>
    <name>D0Z160_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">Thiazole synthase</fullName>
            <ecNumber evidence="4 6">2.8.1.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">thiG</name>
        <name evidence="8" type="ORF">VDA_003274</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 6">Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>1-deoxy-D-xylulose 5-phosphate + 2-iminoacetate + [sulfur-carrier protein ThiS]-C-terminal Gly-NH-CH2-C(O)SH = 2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + [sulfur-carrier protein ThiS]-C-terminal Gly-Gly + 2 H(+) + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:26297"/>
            <dbReference type="Rhea" id="RHEA-COMP:12908"/>
            <dbReference type="Rhea" id="RHEA-COMP:12909"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
            <dbReference type="ChEBI" id="CHEBI:62899"/>
            <dbReference type="ChEBI" id="CHEBI:77846"/>
            <dbReference type="ChEBI" id="CHEBI:90619"/>
            <dbReference type="ChEBI" id="CHEBI:90778"/>
            <dbReference type="EC" id="2.8.1.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 6">Cofactor biosynthesis; thiamine diphosphate biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homotetramer. Forms heterodimers with either ThiH or ThiS.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the ThiG family.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.10" evidence="4 6"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302355.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003274"/>
    <dbReference type="EnsemblBacteria" id="EEZ42241">
        <property type="protein sequence ID" value="EEZ42241"/>
        <property type="gene ID" value="VDA_003274"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2022">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="784095at2"/>
    <dbReference type="UniPathway" id="UPA00060"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990107">
        <property type="term" value="F:thiazole synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd04728">
        <property type="entry name" value="ThiG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00443">
        <property type="entry name" value="ThiG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033983">
        <property type="entry name" value="Thiazole_synthase_ThiG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008867">
        <property type="entry name" value="ThiG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34266">
        <property type="entry name" value="PTHR34266"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05690">
        <property type="entry name" value="ThiG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0704">Schiff base</keyword>
    <keyword evidence="5 6" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ThiG" evidence="7">
        <location>
            <begin position="4"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="DXP binding" evidence="6">
        <location>
            <begin position="182"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="DXP binding" evidence="6">
        <location>
            <begin position="204"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with DXP" evidence="6">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>1-deoxy-D-xylulose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ42241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="255" mass="26674" checksum="E87D9ED37756C164" modified="2010-01-19" version="1">MLTIANKCFSSRLFTGTGKFANGDIMAAAIAESGSQLVTMALKRVELGKKYDDILSPLKQLGVALLPNTSGAKTAEEAIFAARLAREVLGTNWLKLEIHPDPKYLLPDPIETLKAAKALVKEGFVVLPYCHADPVLAKRLEEVGCAAVMPLGAPIGSNKGLVCCDFLDIIIEQARVPVVVDAGIGAPSHAALAMEMGADAVLVNTAIATAQDPLLMAQAFRLAVSSGRLGYQAGLAQAYQTAQASSPLTGFLDGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1C3</accession>
    <name>D0Z1C3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Guanylate kinase</fullName>
            <ecNumber evidence="2">2.7.4.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">GMP kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_003337</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the guanylate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.8" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003337"/>
    <dbReference type="EnsemblBacteria" id="EEZ42304">
        <property type="protein sequence ID" value="EEZ42304"/>
        <property type="gene ID" value="VDA_003337"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0194">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004385">
        <property type="term" value="F:guanylate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008145">
        <property type="entry name" value="GK/Ca_channel_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008144">
        <property type="entry name" value="Guanylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017665">
        <property type="entry name" value="Guanylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00625">
        <property type="entry name" value="Guanylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00072">
        <property type="entry name" value="GuKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03263">
        <property type="entry name" value="guanyl_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50052">
        <property type="entry name" value="GUANYLATE_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Guanylate kinase-like" evidence="9">
        <location>
            <begin position="1"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ42304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="165" mass="18940" checksum="A575E7AEA9F99669" modified="2010-01-19" version="1">MRPGEEHGVHYNFVSVEEFTDLIAQGAFLEHAEVFGNFYGTSRLWIEEQLSKGIDIFLDIDWQGARQIRQLMPNAKSIFILPPSKEELERRLNARGQDSSDVIAGRMQEARSEISHYDEYDYVIVNDDFDVALIDFKAIIRAERLKQAKQAAKYKSMLAALLADQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1C8</accession>
    <name>D0Z1C8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Deoxyuridine 5'-triphosphate nucleotidohydrolase</fullName>
            <shortName evidence="4">dUTPase</shortName>
            <ecNumber evidence="4">3.6.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">dUTP pyrophosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">dut</name>
        <name evidence="6" type="ORF">VDA_003342</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>dUTP + H2O = diphosphate + dUMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10248"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61555"/>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
            <dbReference type="EC" id="3.6.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the dUTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.23" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302528.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003342"/>
    <dbReference type="EnsemblBacteria" id="EEZ42309">
        <property type="protein sequence ID" value="EEZ42309"/>
        <property type="gene ID" value="VDA_003342"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0756">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1669228at2"/>
    <dbReference type="UniPathway" id="UPA00610">
        <property type="reaction ID" value="UER00666"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004170">
        <property type="term" value="F:dUTP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006226">
        <property type="term" value="P:dUMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046081">
        <property type="term" value="P:dUTP catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07557">
        <property type="entry name" value="trimeric_dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00116">
        <property type="entry name" value="dUTPase_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008181">
        <property type="entry name" value="dUTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029054">
        <property type="entry name" value="dUTPase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036157">
        <property type="entry name" value="dUTPase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033704">
        <property type="entry name" value="dUTPase_trimeric"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11241">
        <property type="entry name" value="PTHR11241"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00692">
        <property type="entry name" value="dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51283">
        <property type="entry name" value="SSF51283"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00576">
        <property type="entry name" value="dut"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 4" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="dUTPase" evidence="5">
        <location>
            <begin position="16"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="70"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="87"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ42309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="151" mass="16099" checksum="816096EEBF0578FA" modified="2010-01-19" version="1">MKKIDLKILDPRVGNEFPLPAYATEGSAGLDLRACLDQALTVVPGETHLVPTGLAIHIADNSLAATILPRSGLGHKHGIVLGNLVGLIDSDYQGQLMVSVWNRGQSTFTIEPGDRIAQLVFVPVVQAEFNLVEDFSATDRGEGGFGHSGRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1J0</accession>
    <name>D0Z1J0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type IV pilus biogenesis protein PilM</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_003404</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302654.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003404"/>
    <dbReference type="EnsemblBacteria" id="EEZ42371">
        <property type="protein sequence ID" value="EEZ42371"/>
        <property type="gene ID" value="VDA_003404"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4972">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1750212at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005883">
        <property type="entry name" value="PilM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11104">
        <property type="entry name" value="PilM_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019169">
        <property type="entry name" value="PilM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01175">
        <property type="entry name" value="pilM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ42371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="332" mass="37013" checksum="2494D7EDF9DBBD77" modified="2010-01-19" version="1">MFRNPLSVGIDIGSHSIKAVVVQQKKEQLELAAFAEIVLSTPAVNDQHSVNSTVLLSAMRKLKKHLPRAAKRVVLALPDSAVISKIVQLDTSLSDDETEFAISQALGASSPFPLDELWLDFYPLNNSDRFQDIGSTVPFQIFAARRDTISARLEVAKKAGFKTQVMELQTNGLLWLAEHLTEMSGLQEQWGVIDIGKRHTEFCVKPAMGGVYRREIAFGARHAKHLDKNTPTLLLADEEETFTRQLIDHLKRQIQLYNSTQPRSPLQGVWLCGGSQALVIEQMLQDALKIQVEWVQPFSYLPVGKEVEYLPSTVMTSQYAVAMGLALRGFEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1N9</accession>
    <name>D0Z1N9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">30S ribosomal protein S8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpsH</name>
        <name evidence="7" type="ORF">VDA_003453</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uS8 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302814.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003453"/>
    <dbReference type="EnsemblBacteria" id="EEZ42420">
        <property type="protein sequence ID" value="EEZ42420"/>
        <property type="gene ID" value="VDA_003453"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0096">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1692188at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01302_B">
        <property type="entry name" value="Ribosomal_S8_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000630">
        <property type="entry name" value="Ribosomal_S8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035987">
        <property type="entry name" value="Ribosomal_S8_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11758">
        <property type="entry name" value="PTHR11758"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00410">
        <property type="entry name" value="Ribosomal_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56047">
        <property type="entry name" value="SSF56047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00053">
        <property type="entry name" value="RIBOSOMAL_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ42420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="130" mass="14068" checksum="091FD950ED97F415" modified="2010-01-19" version="1">MSMQDPISDMLTRIRNGQAAKKVAVKMPSSKLKIAIAALLKEEGYVADYTVNGEVKPELEVTLKYFEANPVIEQIQRVSRPGLRIYKKKDALPSVMGGLGIAVVSTSKGLMTDRAARKAGLGGEIICYVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1P8</accession>
    <name>D0Z1P8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">30S ribosomal protein S11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rpsK</name>
        <name evidence="9" type="ORF">VDA_003462</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the universal ribosomal protein uS11 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303517.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="SMR" id="D0Z1P8"/>
    <dbReference type="STRING" id="675817.VDA_003462"/>
    <dbReference type="EnsemblBacteria" id="EEZ42429">
        <property type="protein sequence ID" value="EEZ42429"/>
        <property type="gene ID" value="VDA_003462"/>
    </dbReference>
    <dbReference type="GeneID" id="64243248"/>
    <dbReference type="eggNOG" id="COG0100">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1713391at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01310">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001971">
        <property type="entry name" value="Ribosomal_S11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019981">
        <property type="entry name" value="Ribosomal_S11_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018102">
        <property type="entry name" value="Ribosomal_S11_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036967">
        <property type="entry name" value="Ribosomal_S11_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11759">
        <property type="entry name" value="PTHR11759"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00411">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002131">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03632">
        <property type="entry name" value="uS11_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00054">
        <property type="entry name" value="RIBOSOMAL_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 7 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ42429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="129" mass="13892" checksum="2AB0506B76585125" modified="2010-01-19" version="1">MAKQPTRARKRVRKQVADGVAHIHASFNNTIVTITDRQGNALAWATAGGSGFRGSRKSTPFAAQVAAERCGEMAKEYGVKNLEVMVKGPGPGRESTIRALNAAGYRITNIVDATPIPHNGCRPPKKRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1Q9</accession>
    <name>D0Z1Q9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hypothetical polysaccharide export protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_003473</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303546.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003473"/>
    <dbReference type="EnsemblBacteria" id="EEZ42440">
        <property type="protein sequence ID" value="EEZ42440"/>
        <property type="gene ID" value="VDA_003473"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3206">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1184929at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032807">
        <property type="entry name" value="GNVR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13807">
        <property type="entry name" value="GNVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="425"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="domain" description="GNVR" evidence="3">
        <location>
            <begin position="366"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="167"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="324"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ42440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="479" mass="54890" checksum="5F103BD397E94828" modified="2010-01-19" version="1">MRQLILAKLYAFCCALWMYRYIVLVPMVTLPILLPVGSLFKTKMYYSQTTILVQEAAMLNPFLGDLSISMNLQQRMKALTILLHSQSTLEQVVVDLELASQENKGQIAVRVGELKQHLNLSLLSDELVSIGLTWKYPSEIPVILNTVSNIFLDKLRAPGRASIDNSEQFLQQQLAITQKELEQAEAELASFKTQNANDLPHLRGMNEQANIELNRQLHETELNLMAAKSSRDNLYQRLARTNPLIGMLEQEIVDSESRLALLRASYTDKHSKIRSELRKLSRLQQKRAQLLELQQSLTPDQINQLWQRIANETQAQASTSQPLLLSQFEKLQDADEQIAALSNELNLLKQKAKYLSEKRNVFTRLEKQLTALERNYKVKANIYDQLLERFEMAKVTGQLGRFEDPDKLKIIDKPSIPNQPLNWPWWLNMVIGLILGIILGLSTTTCLMLLDSRIYQLEQLKQTSNSPILAEIPNFHTMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1X1</accession>
    <name>D0Z1X1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 15">Cytochrome b</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">VDA_003535</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 15">Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
        <text evidence="15">Binds 2 heme groups non-covalently.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
        <text evidence="14">Binds 2 heme groups non-covalently.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the cytochrome b family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303725.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003535"/>
    <dbReference type="EnsemblBacteria" id="EEZ42502">
        <property type="protein sequence ID" value="EEZ42502"/>
        <property type="gene ID" value="VDA_003535"/>
    </dbReference>
    <dbReference type="GeneID" id="57339988"/>
    <dbReference type="eggNOG" id="COG1290">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="262439at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045275">
        <property type="term" value="C:respiratory chain complex III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008121">
        <property type="term" value="F:ubiquinol-cytochrome-c reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00284">
        <property type="entry name" value="Cytochrome_b_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.810.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005798">
        <property type="entry name" value="Cyt_b/b6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036150">
        <property type="entry name" value="Cyt_b/b6_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005797">
        <property type="entry name" value="Cyt_b/b6_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027387">
        <property type="entry name" value="Cytb/b6-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030689">
        <property type="entry name" value="Cytochrome_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016174">
        <property type="entry name" value="Di-haem_cyt_TM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00032">
        <property type="entry name" value="Cytochrom_B_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00033">
        <property type="entry name" value="Cytochrome_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038885">
        <property type="entry name" value="COB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81342">
        <property type="entry name" value="SSF81342"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81648">
        <property type="entry name" value="SSF81648"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51003">
        <property type="entry name" value="CYTB_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51002">
        <property type="entry name" value="CYTB_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 15" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5 14 15" id="KW-0349">Heme</keyword>
    <keyword evidence="11 14" id="KW-0408">Iron</keyword>
    <keyword evidence="12 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="19" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 15" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="7 15 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 15" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="33"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="81"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="117"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="146"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="183"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="262"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="324"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="359"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="386"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="domain" description="CYTB_NTER" evidence="17">
        <location>
            <begin position="4"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="CYTB_CTER" evidence="18">
        <location>
            <begin position="243"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="14">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <label>b562</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="14">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <label>b566</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="14">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <label>b562</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="14">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <label>b566</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>a ubiquinone</name>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR038885-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR038885-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU003385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EEZ42502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="421" mass="48122" checksum="4F97302AE85CCAA5" modified="2010-01-19" version="1">MSGFSAWLEKRLPVMNAYKKHLSEYPMPKNFNFWYLFGSLAMLVLVNQLITGIWLTMNYVPSGEGAFASVEYIMRDVDYGWLLRYMHSTGASAFFVVIYLHMYRGLIYGSYQQPRELLWLFGMLIFLVLMAEAFMGYLLPWGQMSYWGAQVIISLFGAIPVIGDDLTLWIRGDYVISGATLNRFFALHVIALPIVLLLLVVLHVLALHEVGSNNPDGIETKLPKGSKGEGYSPQFKFHKYYTKKYDIIDSIPFHPYGTVKDLIGVAVFAFLFSYVIFFNPEMGGYFLEPPNFEAANPLKTPEHIAPVWYFTPFYAILRAVPDKLLGVAAMGLSIIMLFLLPWLDRCKVRSFRYRSKLHLANIAQFTVSFVALGILGALPATPTYTLLAQIFSFAYFMFFVLLFFYSKNEATKPLPERVNYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1Y7</accession>
    <name>D0Z1Y7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CrtC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001959</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299018.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001959"/>
    <dbReference type="EnsemblBacteria" id="EEZ40927">
        <property type="protein sequence ID" value="EEZ40927"/>
        <property type="gene ID" value="VDA_001959"/>
    </dbReference>
    <dbReference type="GeneID" id="57341902"/>
    <dbReference type="eggNOG" id="COG5621">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="591394at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.370.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023374">
        <property type="entry name" value="AttH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010791">
        <property type="entry name" value="AttH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07143">
        <property type="entry name" value="CrtC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CrtC" evidence="1">
        <location>
            <begin position="65"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="359" mass="41086" checksum="81734FC0D0D44111" modified="2010-01-19" version="1">MTKQFTHFIYLALALTLLVGCNKKTERSNTAEVLTRSDEYVYEPVVRGEPVEFPRDYGAHPEYRTEWWYLTANVKSPEGKEFGIQWTLFRMATSTEKETGWKTPQMYMAHAVITSKSKVWSAERFARGGIGQAGVTSTPYHAWLDNWSWKALGKTPFPGMVEFADDGMAAVLKVTQHGPIVLQGDQGYSKKHPELDMASRYFSAPFLDIDGKITLDGTEYQVSGEAWLDREWSSSMLAKDQLGWDWFSIHLNDGSALMVSQLREKDDLPYYFGSRSWPNGKVVQLDHTQIRLTPLSYTRIDGKKFPLQWRIDVPSQNIKLTVNVLRKDQWLPFVFPYWEGPIHVTGSHSGQGFMELTGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z244</accession>
    <name>D0Z244_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative heat shock protein HslJ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001780</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298686.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40748">
        <property type="protein sequence ID" value="EEZ40748"/>
        <property type="gene ID" value="VDA_001780"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3187">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2029962at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005184">
        <property type="entry name" value="DUF306_Meta_HslJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038670">
        <property type="entry name" value="HslJ-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03724">
        <property type="entry name" value="META"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0346">Stress response</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019993" evidence="1">
        <location>
            <begin position="20"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="META" evidence="2">
        <location>
            <begin position="33"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="150" mass="16135" checksum="1069CDD21D7DE95E" modified="2010-01-19" version="1">MKKRLLTVLALPMMLAACASNNVNTPAKPATAAELTGQTWVLTEVDNQVLNMAEPDVAPTLELSKDLGASGHSGCNRYFGQAELKDGQLRIEKMGMTMMACPEPAMLVEGTITEALSNWSTAKVAGDTLTLQSPKHKLTFTRKAENQDAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z267</accession>
    <name>D0Z267_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SH3b domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001914</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298926.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001914"/>
    <dbReference type="EnsemblBacteria" id="EEZ40882">
        <property type="protein sequence ID" value="EEZ40882"/>
        <property type="gene ID" value="VDA_001914"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502ZM7Q">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2015672at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003646">
        <property type="entry name" value="SH3-like_bac-type"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51781">
        <property type="entry name" value="SH3B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019915" description="SH3b domain-containing protein" evidence="2">
        <location>
            <begin position="24"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="SH3b" evidence="3">
        <location>
            <begin position="16"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="209" mass="22754" checksum="BD0658EECBC63F9A" modified="2010-01-19" version="1">MKKGVVFTLAGAAALVASSLVWAANNNDVGNITIYSQPNAQSKVIEKINGDAPLMTIFIDKDWSKVGDPSNGQTGWVKNSDMQNATKSVAAKSNQTTKTTKTDDGVQTVTKGVVQTQYGPMHYEITQFQGKSAPNNKEAKAFFNKMQKMQIDMNNAFANSWGDMDSMQANMMKMMGEQQHIMMQMDQPTKPAVKTGQPKAVSSATSETK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z272</accession>
    <name>D0Z272_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001932</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40900">
        <property type="protein sequence ID" value="EEZ40900"/>
        <property type="gene ID" value="VDA_001932"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031CWW">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="278" mass="31097" checksum="3FCCC55C06DCFE21" modified="2010-01-19" version="1">MICFDLDMTLFFSFRYFCRLLLIAVLWSCSTSSFACIERQIKNVSLYEPNCEFSVSRKESTNNKAYVQFQYQKKNLMETMQVMQSLTSSLPYAISIHSYQNGFRSMVGPVEQKDIAKVKRALAQKGYRETLVKYLASNSDSDAISQSQAAALIAQSRSQAHRANKKIAQQYVGYRIGKVGTNDLIVPVKKESNEAMSNRVGRFAYQDTKAICQGIQGQASIATVDEYAAVLSSTEALNKIGLSVPFWLTSDTVITRSSKGLERRAASPNIQYNVLCSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z276</accession>
    <name>D0Z276_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001921</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298941.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40889">
        <property type="protein sequence ID" value="EEZ40889"/>
        <property type="gene ID" value="VDA_001921"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031N7A">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1886306at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="103" mass="11669" checksum="D7FB7888D21CD59F" modified="2010-01-19" version="1">MDNFAAAEKALSAMLKNVSATGEVKEARTDYRQILIDFADEVPGRQKAVIKRMPLQKINNLISVLHEFKEEARQARMIEIMALMEKDGVHPEDLIQTISAEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2B9</accession>
    <name>D0Z2B9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Flavocytochrome MsrQ</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">msrQ</name>
        <name evidence="10" type="ORF">VDA_000570</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
        <text evidence="8">Binds 1 FMN per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
        <text evidence="8">Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the MsrQ family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304737.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000570"/>
    <dbReference type="EnsemblBacteria" id="EEZ39550">
        <property type="protein sequence ID" value="EEZ39550"/>
        <property type="gene ID" value="VDA_000570"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2717">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1508607at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030091">
        <property type="term" value="P:protein repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01207">
        <property type="entry name" value="MsrQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022837">
        <property type="entry name" value="MsrQ-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36964">
        <property type="entry name" value="PTHR36964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 8" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0288">FMN</keyword>
    <keyword evidence="8" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8" id="KW-0408">Iron</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="51"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="80"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="148"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="172"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="Ferric oxidoreductase" evidence="9">
        <location>
            <begin position="49"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ39550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="206" mass="23807" checksum="7DF66D99ED9ECFDC" modified="2010-01-19" version="1">MRITPKQITIIKSMVHIFSLIFMIYFILLTLQGGFGADPVKGMEHFTGKAALNMLILTLLVSPLAKGFRQGLLMKLRRMLGLYSFFWATLHFAIYISLDLGFDFSLLGEEIFKRPYLTIGAVCWVILLLLAATSFQKIQRKMGKKWQTLHYWVYLALILAPIHYYWSVKSGLIEPSLYLVVTVLLLIWRKDFFMRLLGKFSISVKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2H1</accession>
    <name>D0Z2H1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">NH(3)-dependent NAD(+) synthetase</fullName>
            <ecNumber evidence="4 6">6.3.1.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">nadE</name>
        <name evidence="9" type="ORF">VDA_000622</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 6">
            <text>ATP + deamido-NAD(+) + NH4(+) = AMP + diphosphate + H(+) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:21188"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.1.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4 7">Cofactor biosynthesis; NAD(+) biosynthesis; NAD(+) from deamido-NAD(+) (ammonia route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the NAD synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.1.5" evidence="4 6"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304895.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000622"/>
    <dbReference type="EnsemblBacteria" id="EEZ39602">
        <property type="protein sequence ID" value="EEZ39602"/>
        <property type="gene ID" value="VDA_000622"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0171">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1152435at2"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00333"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003952">
        <property type="term" value="F:NAD+ synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008795">
        <property type="term" value="F:NAD+ synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00553">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00193">
        <property type="entry name" value="NadE_ammonia_dep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022310">
        <property type="entry name" value="NAD/GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003694">
        <property type="entry name" value="NAD_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022926">
        <property type="entry name" value="NH(3)-dep_NAD(+)_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23090">
        <property type="entry name" value="PTHR23090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02540">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00552">
        <property type="entry name" value="nadE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 5 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 5" id="KW-0520">NAD</keyword>
    <keyword evidence="2 4 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD_synthase" evidence="8">
        <location>
            <begin position="21"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="43"/>
            <end position="50"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>deamido-NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>deamido-NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>deamido-NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="217"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="266"/>
            <end position="267"/>
        </location>
        <ligand>
            <name>deamido-NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ39602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="278" mass="30556" checksum="0071B2D2B2BB3A5D" modified="2010-01-19" version="1">MEQLIRQNMRVLPSIDVEFEIQRRISFIQKKLKVSGSKSLVLGISGGVDSTTCGRLAQLAVEGLNKELNTTDYQFIAVRLPYGEQQDEDEAQLALQFIQPTHSISINIKTGVNGTHASTLDALDGTGLIPKDEAKVDFVKGNVKARTRMIAQYEVAGLVGGLVLGTDHSAENITGFYTKFGDGACDLAPLFGLNKRQVRQIAAHLGAPESLVIKVPTADLEELAPQKADEDALLVSYDQIDDFLEGKDVEPHVIERLVNIYKATEHKRQPIPTIYEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2R2</accession>
    <name>D0Z2R2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hypothetical acyl dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000713</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305134.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000713"/>
    <dbReference type="EnsemblBacteria" id="EEZ39693">
        <property type="protein sequence ID" value="EEZ39693"/>
        <property type="gene ID" value="VDA_000713"/>
    </dbReference>
    <dbReference type="GeneID" id="57342968"/>
    <dbReference type="eggNOG" id="COG2030">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1380653at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03450">
        <property type="entry name" value="NodN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002539">
        <property type="entry name" value="MaoC-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039375">
        <property type="entry name" value="NodN-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01575">
        <property type="entry name" value="MaoC_dehydratas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MaoC-like" evidence="1">
        <location>
            <begin position="85"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="227" mass="26284" checksum="8ECC5BA44E5D02F4" modified="2010-01-19" version="1">MKVVEFIKQKREDLARHQFEFKDWLSPSIRDYWIEFLNKANNSQLANWAKEHNFKFVSNGEAIQETVQIELHPEAEKLMNELLDTLGEEIHVGNWLTVDQSRINQFADVTDDHQWIHTDPERAQQESPFKTTIAHGFLTLSLLSVLTDSVDPETQKFPTAKMTVNYGLNQVRFPYPVKEGSNVRARTKIQSVTPIKRGLEIVQEITVEIEGCRRPGCVAESVIRLYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2R6</accession>
    <name>D0Z2R6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_000717</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305144.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000717"/>
    <dbReference type="EnsemblBacteria" id="EEZ39697">
        <property type="protein sequence ID" value="EEZ39697"/>
        <property type="gene ID" value="VDA_000717"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1120">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1752365at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="3"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="249" mass="27460" checksum="6896E0B1CB290308" modified="2010-01-19" version="1">MSLAINNITVIYGQHRVLDNFTLPNICCGEVVTLIGKNGAGKSTLLKHLTHPKNLLTSTISWQNQPLDTKQIGYLPQDHRIHAAITVIELLITALNVHSNSLFVKSNSAERALQLLDEMDILHLANKTCTELSGGESQMVGLAQAVINQPKVLILDEPTSALDMKNQLKLLSYVRKYAKHHQACVLMVVHDLNLAIQYSDKVAALNQGQLAQFGAPKEIISTQLIQDIFEVESEIIPMNDYPIVIVKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2U1</accession>
    <name>D0Z2U1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Zinc carboxypeptidase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000742</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000742"/>
    <dbReference type="EnsemblBacteria" id="EEZ39722">
        <property type="protein sequence ID" value="EEZ39722"/>
        <property type="gene ID" value="VDA_000742"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2866">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040626">
        <property type="entry name" value="Pepdidase_M14_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000834">
        <property type="entry name" value="Peptidase_M14"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18027">
        <property type="entry name" value="Pepdidase_M14_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00246">
        <property type="entry name" value="Peptidase_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00631">
        <property type="entry name" value="Zn_pept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M14" evidence="1">
        <location>
            <begin position="40"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="303" mass="34494" checksum="1243432D4C24D29D" modified="2010-01-19" version="1">MASYDREEWFRIPAEFDGDTLSFSIIPEHGSMYFAYFAPYSYDRHQDLIHLAQAQHNCRLETLGHTLDGNDMSLLTIGEPDEGKKKVWLIARQHPGETMAEWFMEGVVQRLLDETDTVARALLDQAVFYIVPNMNPDGAIRGHLRMNSIGVNLNREWAEPSLERSPEVYHVRQRMLETGIDFFLDVHGDEAIPYNFVAGSEGIPSYDAYLADLENTFKQALLTVTPEFQDEHGYGKDEPGKANLTICSNWVGETFKCLSYTVEMPFKDHNNHPDSLFGWSPERSIMFGHDTLAAILATLPKVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2Y7</accession>
    <name>D0Z2Y7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TPR repeat protein SEL1 subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000788</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305349.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000788"/>
    <dbReference type="EnsemblBacteria" id="EEZ39768">
        <property type="protein sequence ID" value="EEZ39768"/>
        <property type="gene ID" value="VDA_000788"/>
    </dbReference>
    <dbReference type="GeneID" id="57342712"/>
    <dbReference type="eggNOG" id="COG0790">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018861" evidence="1">
        <location>
            <begin position="23"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="333" mass="37997" checksum="5A8598BEB2CFF4C9" modified="2010-01-19" version="1">MNYRRTLLSIGITLFLSTPAFAYDLSYEEYTSEDLAVVKKAETSTDAEVIYNAANILMSESMMQENIEQGIKYLNQLAENNHPKATLTLADYYYEEEDYTKALKLYHQLESSQDPYVLYSLGIMYFDGEGTAQDYEKGNEYYLAAAKLGYSDAMYQLAFSYNDGQGVKQDFTEAAKWFQKSADQGDASAMYNLGIAYLNGEGVKKDCARAIQFFEKAIETDEHARSYAKLGDIYYYTDYKAQCGFKKTDYKKSLAYFTQGAMRGNEYSQYMVGYSYRNGHGTYSNFKTALAWYNIAEDNGYDASSEIKDVKQYMSADDIAKAAQLQQEIYDKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z310</accession>
    <name>D0Z310_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Outer membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000811</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305414.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000811"/>
    <dbReference type="EnsemblBacteria" id="EEZ39791">
        <property type="protein sequence ID" value="EEZ39791"/>
        <property type="gene ID" value="VDA_000811"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1538">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1099555at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018806" evidence="2">
        <location>
            <begin position="26"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="479" mass="52973" checksum="8212FD907338CA75" modified="2010-01-19" version="1">MRVKPFTLPKLALALFALSPIAGQAESVSFSQAWQTVVSQNEGLAAERTKVDQAKYLQDAAWDLNLPQVSVGANYTRLDDNIEISPSDLFSSMPASGSDAGKVISQLAEQLSKLTGTDFNSLFTSQITDKDVFTSSIRAIWPIFTGGRINAAQAIAEGKTEEAKYMLAMKKQATYEDLSRFYFGVVLAEQVYKTRQEVEAGLKQHFEHAVKLQQQGQIARVERLQAEAAYDKAKVETQKSKRDLEIVQVALTKLLNASSPITPTTTLFTNEQLPNLDSFLSQTLTTYPGLHLLDAKRKQANGLIDVEKGKYYPEVYLYGNYNIYDGHSLAAELTPDWAVGVGVNIPLIDNTGRSGKLKAAHSAVSQVNHLQAQAKQDLSVLVEKTYKEANQALEEYQGLQSSLNLANENVRLREKAFSQGLSTSLDVVDAELFLASIKTQRLAASYQYITSLTRLLAISGQMSEFNQYQKYRGLEVQSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3B5</accession>
    <name>D0Z3B5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000916</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000916"/>
    <dbReference type="EnsemblBacteria" id="EEZ39896">
        <property type="protein sequence ID" value="EEZ39896"/>
        <property type="gene ID" value="VDA_000916"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG50332S5">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="193" mass="21978" checksum="07D839A0E03E3C35" modified="2010-01-19" version="1">MIRVSEFLPSLRLLVDVPLPGLMERAIIQASIRFCRESRSLVKRRSFEEVFELQTISAISRQYDIKGIPQLKGAGLISVSSQSQLLEAGVDYTVLGLDKITFQQDFIDVEIYARAEPTQSAAMLPEELYHDYCDVICSGAAAILQMQPNQTWTGPNLAKYNEQCFVEGYRQAFRHAVEHQSFTSRPERKRVFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3F5</accession>
    <name>D0Z3F5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000956</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305828.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000956"/>
    <dbReference type="EnsemblBacteria" id="EEZ39936">
        <property type="protein sequence ID" value="EEZ39936"/>
        <property type="gene ID" value="VDA_000956"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031T46">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1538705at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021316">
        <property type="entry name" value="DUF2913"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11140">
        <property type="entry name" value="DUF2913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="190" mass="22013" checksum="EED26B4EEACFFE59" modified="2010-01-19" version="1">MNQSQQLLDVTTNALLHLEFKKLEKTLSLAERNTLLIHFLKRIVKSNQYRGAKKPARQWLSLGRQSGADLETILVQHHESLLQTCSSDLYRFVDLIQKIEANLETKVQYSQAHRIDLNARYGRVLVCVVDEDLTSSFDEDGLMIKSTQILFIGQAADKELFSQFVEESTYFQSVVAYEDEMHLRVELFRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3K9</accession>
    <name>D0Z3K9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_001010</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305978.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001010"/>
    <dbReference type="EnsemblBacteria" id="EEZ39990">
        <property type="protein sequence ID" value="EEZ39990"/>
        <property type="gene ID" value="VDA_001010"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1031685at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="204"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="223"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="283"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ39990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="481" mass="54827" checksum="F40BC1FBB20DEC58" modified="2010-01-19" version="1">MQLKSIWPKSLLARTLWLTLLAVFFAQLISTMIWYSQSKQRDLKGLESTSASMATMFASTVNFFQSLPTEYRHIVLDQLRNMGGTRFFVSFNSEKIRITPIANSELKQAAISTFETVLHDKLPQQDQIKVEFSRPETLHVLKNDILLSDLPKSWAHYTLSLEPLSPPILVVQIQLEHNQWLYIAALLPAPYMMLEDQIMTSHQVFSLLFTTLLLLVFTYLMISKQTKPLKRLANAANALSLDIYQPPIKEEGASEIVTATRAFNRMQLRLMRYIDDREKLFSSISHDLKTPITRLRLRAELIDDESKIEKFNRDLDELEMMVKGALQCVRDTDLHENLVTVDVLDILHHIAEGHNSQQRKVRILEKPIAPLMAKPLALKRCFTNLIDNGVKYGERVTVLISDESDALVLIIKDQGKGIPLEQQDAVFEPYYRLAKDKDGHGLGMGIARNIVRAHGGDLTIHNANDGGLEVKVFLPRFANNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3P2</accession>
    <name>D0Z3P2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">L-proline Glycine Betaine ABC transport ATP-binding protein proV</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_001043</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001043"/>
    <dbReference type="EnsemblBacteria" id="EEZ40023">
        <property type="protein sequence ID" value="EEZ40023"/>
        <property type="gene ID" value="VDA_001043"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0517">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031460">
        <property type="term" value="P:glycine betaine transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005892">
        <property type="entry name" value="Gly-betaine_transp_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01186">
        <property type="entry name" value="proV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="14"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="400"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="400"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="70"/>
            <end position="77"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="425" mass="47103" checksum="B0EE23CD4D7FEFFC" modified="2010-01-19" version="1">MSYSAAQPTQAPLIRVKKLYKVFGPKAKQVLTQVKAGESKDDILAQTGHTVGLSDINLDIYSGEIFVVMGLSGSGKSTLIRHFNRLIEPTEGVIEVDGTDVLSLKEKDLQHFRRHKMSMVFQRFGLMPHKTVLENVSYGLQVQGVNKETRITKAQEWLTTVGLDGYENQYPASLSGGQQQRVGLARALCTDAEILLMDEAFSALDPLIRSEMQDQLIELQEKLHKTIVFITHDLDEALRLGDRIAILRDGVLVQQGKPVDILLNPADDYVEAFVKDVNRARALTVETVMKPQIVRISAQTIGDAVNQMRQVKEDYGYYVTDEGYQGVITQESLDEISESQYHQAIPDSLVESVPAVTTDALLESVIPETLDSDHPLPVIDELGEVKGRLSRSTLAEILSDQTDSNKAEVAQNETIKKSQTETKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3U4</accession>
    <name>D0Z3U4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001097</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306211.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40075">
        <property type="protein sequence ID" value="EEZ40075"/>
        <property type="gene ID" value="VDA_001097"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031N84">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2231823at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019389" evidence="1">
        <location>
            <begin position="23"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="171" mass="17618" checksum="4175B478C2C913CD" modified="2010-01-19" version="1">MKKTMTTLAIAGLCAMSAGAFAATDSANAVVTWKGTVPGVLPGNTITVTGLGGGDIPAGQLNVLEDGTFASAESVILESRSYDETKPESERTGDLIQATWKLKAVSVSPASYHKEDVKVSFNNSEIAVGTDLGDLTDTISVDVRNDVANDQVTPSQSVQVTTIAVASVEVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3W8</accession>
    <name>D0Z3W8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001121</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001121"/>
    <dbReference type="EnsemblBacteria" id="EEZ40099">
        <property type="protein sequence ID" value="EEZ40099"/>
        <property type="gene ID" value="VDA_001121"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="51" mass="5688" checksum="A81927B6EC746BD2" modified="2010-01-19" version="1">MQMAAEMLLERDVIGFNEFTEQALAAGRRGITCLTLQLNTHHQVESVEDGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z414</accession>
    <name>D0Z414_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001167</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306393.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40145">
        <property type="protein sequence ID" value="EEZ40145"/>
        <property type="gene ID" value="VDA_001167"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5032KWC">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1994841at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="199" mass="23369" checksum="E77994951645FA35" modified="2010-01-19" version="1">MARVKITPHNFKEKFLLSSNTKMKLTNITIYQHRVNVINNDRTALFTVEMSSYYKNWITAYECYGFDCSVLDFIDDIANSVGIDENLLKAIIYMETRNCHSNPFHRSHPNPFPININYQLWEPIVHQLGYSMEDIKYSEMARVHLAAVVLKRIALRLNEPCVVRVATLYNSLNKHETSSYGHRVGEIYLDKIWEKYRNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z427</accession>
    <name>D0Z427_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">[NiFe] hydrogenase nickel incorporation-associated protein HypB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000283</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303938.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000283"/>
    <dbReference type="EnsemblBacteria" id="EEZ39265">
        <property type="protein sequence ID" value="EEZ39265"/>
        <property type="gene ID" value="VDA_000283"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0378">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1134430at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051604">
        <property type="term" value="P:protein maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05390">
        <property type="entry name" value="HypB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003495">
        <property type="entry name" value="CobW/HypB/UreG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004392">
        <property type="entry name" value="Hyd_mat_HypB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30134">
        <property type="entry name" value="PTHR30134"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02492">
        <property type="entry name" value="cobW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00073">
        <property type="entry name" value="hypB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="cobW" evidence="3">
        <location>
            <begin position="173"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="45"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="71"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="358" mass="40377" checksum="3D8217FCB3C25595" modified="2010-01-19" version="1">MCSVCGCGDSQVEGHTHHHHHEDKTSTPTVIVHHHYYNQGDVHLHIYGSNGDVKSSNPGQGHHHSHTHDHHDHHDHHDHHDHHDHHDHHDHHDHHDHHDHHDHHDHHDHHDHHDHYPEQLESGDLHYGKGEAQVHVSGVSQRQLLTLEQDILGNNNHLAAYNRQHFSEHQQCVLNLVSSPGSGKTTLLTETLTLLSKQWPCAVIEGDQQTTNDADRIRATGVAAIQVNTGKGCHLDAQMVHDAYHQLASNERGFIFIENVGNLVCPASFDLGEDCKVAILSVTEGEDKPLKYPNMFAAAKVMVLNKVDLLPYLDFDIDTCIANARRVNPQIQIIKLSAKTGEGMAAWLTWLNEQLVQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z445</accession>
    <name>D0Z445_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000301</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000301"/>
    <dbReference type="EnsemblBacteria" id="EEZ39283">
        <property type="protein sequence ID" value="EEZ39283"/>
        <property type="gene ID" value="VDA_000301"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="7"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="301" mass="33832" checksum="16476F1FEFE24816" modified="2010-01-19" version="1">MMKVMMLNPIWLKTFTTLIDTGHFTKTAQKLFMTQPGVSQHIKKLEEYCGYPLIIREKKSFELTEQGRLVYQYSQQLEKNEQTLLDQLGSDDPFCGTCSIACSGSLALSLYPALLHVQSQHPQLNIHIEAAPNHKILHEITSGDIELGIVTQQPNSGLFDFKTVGFENLYLIVPHRAHTTITPDDLLSLGLIDHPDAQLYLSMFFTQCGDKKLAEMDTSTLPVSSYINQLSQILLPIAMGVGFTVLPKSAVDQFTSKDKLTVIQTPQTVSETLYLVKKKHRVLGARYCTIEKVITELFNQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z473</accession>
    <name>D0Z473_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">(GlcNAc)2 ABC transporter permease component 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_000329</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304062.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000329"/>
    <dbReference type="EnsemblBacteria" id="EEZ39311">
        <property type="protein sequence ID" value="EEZ39311"/>
        <property type="gene ID" value="VDA_000329"/>
    </dbReference>
    <dbReference type="GeneID" id="57342522"/>
    <dbReference type="eggNOG" id="COG0601">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1479518at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045621">
        <property type="entry name" value="BPD_transp_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19300">
        <property type="entry name" value="BPD_transp_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="101"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="138"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="189"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="247"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="298"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="99"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="328" mass="36619" checksum="32F5AF8F5B9BF24A" modified="2010-01-19" version="1">MSFFLRRLMFYVIALFFAATLNFILPRMMPGDPVTMMFANAMAHVSPEKIEAMKKLLGFVDGPLYQQYFSYLANIFTGNWGTSIKFYPLSVNELLGSAMGWSLFLTGTAIIISFCIGSTLGIFAAWRRGSNYDAFISPGMLVIQSVPSVVIAMLVMFIFAIGLEWFPTGNAYTPGTIPDWSSWDFYKDVAYHMVLPLVCATVTQIGGFLINMRNNMINLLNEDFITMAKAKGLSENRIVFNYAARNAMLPSVTALSMALGTAIGGQLIVEMIFNYPGLGTVLLNAIHARDYQVLQGQLLLMTLFMLFFNFMADLLIVFLDPRLRNGSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4A2</accession>
    <name>D0Z4A2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000358</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39340">
        <property type="protein sequence ID" value="EEZ39340"/>
        <property type="gene ID" value="VDA_000358"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031PWK">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="964266at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="258" mass="28294" checksum="FE4DB01C22721ED0" modified="2010-01-19" version="1">MANISRVIFTLSALTLFGCGGGGSDSPKPTPKVSAKVGIYGVDDAVMLVDSTLKGGVFAHVSEQQGKKETNLQFASFKNEITKIDSGNVKAWLVDQTLTPFDGGHQWHQEINYAHNSEQKFAVTFQDNNNQASTFGSVYGVPFTYAFSKQPKSESLDQLSGVYQNNQLGSSWNIQPSGYLKVTKADNCTFEGTVKAATDTVYFSGSVIRTCPAYKDPKQEDVKLNAIVFSTKSGDKTTINSIFYDNNELLEWFTVEQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4D8</accession>
    <name>D0Z4D8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000394</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000394"/>
    <dbReference type="EnsemblBacteria" id="EEZ39376">
        <property type="protein sequence ID" value="EEZ39376"/>
        <property type="gene ID" value="VDA_000394"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3530">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024530">
        <property type="entry name" value="QSregVF_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40613">
        <property type="entry name" value="PTHR40613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12843">
        <property type="entry name" value="QSregVF_b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="64" mass="7384" checksum="23F0E1FA3DF10BC5" modified="2010-01-19" version="1">MKLANTKMPFGKYSGRVIIDLPEEYLLWFQKKGFPEGELGLLMALALEFRVEGLESVIRPLRNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4E0</accession>
    <name>D0Z4E0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000396</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304250.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000396"/>
    <dbReference type="EnsemblBacteria" id="EEZ39378">
        <property type="protein sequence ID" value="EEZ39378"/>
        <property type="gene ID" value="VDA_000396"/>
    </dbReference>
    <dbReference type="GeneID" id="57343217"/>
    <dbReference type="eggNOG" id="ENOG5031IC3">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1699669at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021378">
        <property type="entry name" value="DUF3010"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11215">
        <property type="entry name" value="DUF3010"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="140" mass="16092" checksum="60F6E13CFAE08DB0" modified="2010-01-19" version="1">MKICAVELRSNEAVICLLTLEQGVFGIPECRTQKFIMDDAWDNQKMRDFQFAFKKLLEDYQVDKVVIRSRETRGKFAGSAIGFKLETAIQLIDGLDVSFMSNSDIKQKLKRNPMMIEFRATGLRQFQEAAFTTAYAFLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4F5</accession>
    <name>D0Z4F5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000411</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304293.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39393">
        <property type="protein sequence ID" value="EEZ39393"/>
        <property type="gene ID" value="VDA_000411"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="103" mass="12330" checksum="4FECB05D895EA734" modified="2010-01-19" version="1">MDTSKITEAYKQIKTIKDAVQQTLTQPDANYNQEQLQVLLMQLDKVQDELFFIREEVFESTKNYKQLHKESKEQEARIIHLKKSATQHNHQRSTHRATSWRCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4G2</accession>
    <name>D0Z4G2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hypothetical membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000418</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304312.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000418"/>
    <dbReference type="EnsemblBacteria" id="EEZ39400">
        <property type="protein sequence ID" value="EEZ39400"/>
        <property type="gene ID" value="VDA_000418"/>
    </dbReference>
    <dbReference type="GeneID" id="57342577"/>
    <dbReference type="eggNOG" id="ENOG50332Y0">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1541436at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021354">
        <property type="entry name" value="DUF2975"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11188">
        <property type="entry name" value="DUF2975"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="182" mass="20900" checksum="7CDF221A9DDFAA02" modified="2010-01-19" version="1">MTNIQKQSRRVRLFFQCLLFLTPIGVCYYWLTVQTPNDFLTMMGFVQTSIDIGSYTQQPLTMMTRILAMISSLLLSGVILYALRVLIHLFKNYEQNEIFTLDNAKCYRKLGYSIFYWVGGSVVYGTAMSVILSFNNPPGERLLTVTFAGIDFLTLIFGMIILIISWVMQEGFRIADENNHTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4G6</accession>
    <name>D0Z4G6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 13">Aspartate-semialdehyde dehydrogenase</fullName>
            <shortName evidence="13">ASA dehydrogenase</shortName>
            <shortName evidence="13">ASADH</shortName>
            <ecNumber evidence="8 13">1.2.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Aspartate-beta-semialdehyde dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">asd</name>
        <name evidence="15" type="ORF">VDA_000422</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 13">Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>L-aspartate 4-semialdehyde + NADP(+) + phosphate = 4-phospho-L-aspartate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:24284"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57535"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="1.2.1.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4 13">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 2/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 13">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 2/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5 13">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 2/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7 13">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 13">Belongs to the aspartate-semialdehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.11" evidence="8 13"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304324.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000422"/>
    <dbReference type="EnsemblBacteria" id="EEZ39404">
        <property type="protein sequence ID" value="EEZ39404"/>
        <property type="gene ID" value="VDA_000422"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0136">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1799040at2"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00016"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00463"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00464"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004073">
        <property type="term" value="F:aspartate-semialdehyde dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071266">
        <property type="term" value="P:'de novo' L-methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019877">
        <property type="term" value="P:diaminopimelate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02121">
        <property type="entry name" value="ASADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000319">
        <property type="entry name" value="Asp-semialdehyde_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011534">
        <property type="entry name" value="Asp_ADH_gamma-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012080">
        <property type="entry name" value="Asp_semialdehyde_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000534">
        <property type="entry name" value="Semialdehyde_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012280">
        <property type="entry name" value="Semialdhyde_DH_dimer_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46278:SF4">
        <property type="entry name" value="PTHR46278:SF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01118">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02774">
        <property type="entry name" value="Semialdhyde_dhC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00859">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ASD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="10 13" id="KW-0220">Diaminopimelate biosynthesis</keyword>
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    <keyword evidence="13" id="KW-0521">NADP</keyword>
    <keyword evidence="13 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 13" id="KW-0791">Threonine biosynthesis</keyword>
    <feature type="domain" description="Semialdhyde_dh" evidence="14">
        <location>
            <begin position="4"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="13">
        <location>
            <position position="140"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="13">
        <location>
            <position position="279"/>
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    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="11"/>
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        <ligand>
            <name>NADP(+)</name>
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        <location>
            <position position="78"/>
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        <location>
            <position position="107"/>
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        <ligand>
            <name>phosphate</name>
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        </ligand>
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            <position position="167"/>
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        <ligand>
            <name>substrate</name>
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        <location>
            <begin position="170"/>
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        <ligand>
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        <location>
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            <name>substrate</name>
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        <location>
            <position position="248"/>
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        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
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        <location>
            <position position="272"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
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        <location>
            <position position="355"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001636"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00002492"/>
        </source>
    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00010584"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00013120"/>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00022697"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022915"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02121"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SMART" id="SM00859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEZ39404.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="378" mass="41530" checksum="B69B0556B128BC82" modified="2010-01-19" version="1">MKLKVGFIGWRGMVGSVLIQRMLEEQDFANIETVFFSTSQVGQQIPSWIKTITKTESNLADAYDLEQLRQLDIIVTCQGGDYTNKTYQPLRQLGWNGYWIDAASSLRMADDSIIVLDPINQDQIHNGIQQGIKTYVGGNCTVSLMLMAIGGLYQAGLVEWMTSQTYQAASGAGAQNMRELIEQMGSIYSSVNTELQAATSILDIDRMVATRLREAEFPTAAFGAPLAGSLIPWIDCALENGQTKEEWKGGVETNKILGTAAKPIAIDGTCVRIGAMRCHSQALTIKLTRPVPLDEIEQIIASHNPWVKVIPNTKEATLSELTPAKVTGTLSIPVGRIRKLAMGEDYLNVFTVGDQLLWGAAEPLRRMLNIIVDQHNAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4H0</accession>
    <name>D0Z4H0_PHODD</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
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        <name evidence="1" type="ORF">VDA_000428</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
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    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
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        <property type="component" value="Unassembled WGS sequence"/>
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        <property type="entry name" value="DUF2750"/>
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    <dbReference type="Pfam" id="PF11042">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="130" mass="15137" checksum="BA96A858A61EBEBA" modified="2010-01-19" version="1">MTTPLDDAKIAEIQAFDAEKRYKYLVKEVVANREIWILIDEHGCVMLNTEDEDCVPVWPNKEFAEAWATGDWAECKAESISLNKWHSRWTHGLEDDELAVVIFPNQDEDGLVVFPDELDFELKQQVKKQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4H2</accession>
    <name>D0Z4H2_PHODD</name>
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        <submittedName>
            <fullName evidence="5">Hypothetical cytosolic protein</fullName>
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    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_000430</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Gammaproteobacteria</taxon>
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            <taxon>Photobacterium</taxon>
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    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
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                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5 6">CIP 102761</strain>
        </source>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Beta_helix"/>
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        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001434">
        <property type="entry name" value="DUF11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045474">
        <property type="entry name" value="GEVED"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13229">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GEVED"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01451">
        <property type="entry name" value="B_ant_repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019996" evidence="2">
        <location>
            <begin position="25"/>
            <end position="3902"/>
        </location>
    </feature>
    <feature type="domain" description="Beta_helix" evidence="3">
        <location>
            <begin position="342"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="domain" description="GEVED" evidence="4">
        <location>
            <begin position="857"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="domain" description="GEVED" evidence="4">
        <location>
            <begin position="1415"/>
            <end position="1506"/>
        </location>
    </feature>
    <feature type="domain" description="GEVED" evidence="4">
        <location>
            <begin position="1843"/>
            <end position="1929"/>
        </location>
    </feature>
    <feature type="domain" description="GEVED" evidence="4">
        <location>
            <begin position="2401"/>
            <end position="2475"/>
        </location>
    </feature>
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        <location>
            <begin position="2961"/>
            <end position="3035"/>
        </location>
    </feature>
    <feature type="domain" description="GEVED" evidence="4">
        <location>
            <begin position="3436"/>
            <end position="3514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="806"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1363"/>
            <end position="1383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1778"/>
            <end position="1805"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2324"/>
            <end position="2372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="2345"/>
            <end position="2361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF20009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="3902" mass="409671" checksum="0E67088860F3058B" modified="2010-01-19" version="1">MFNINKIINIIVLLLVFISNSALAASVSGTVFEDITGDGLIDGDFTFNDNLGDQRGLPGVTVTIYLDDGDNLPDSGDTVVATDVTDANGEYSFTGLANAVYWVASDAPTTASNGSGGLVAEQTIGMEALSTIPTPFAVQSYCADGAGGSVLTTNTTHNFDVCYGGKTATGADVTTDAGTREHITGLYLDYDLGNLSFGFSFNIVVNTEFDGVGSYQQFLLNANAYSGANTMRFVPVVPPNRASWWEVENQDFDFVMLVFPTITEGNITIDGTAHDFSDATLLRDLDSTLLGTTTTVGADWNSRSISQVDAPDFAINHIADNCLRSYYGQTQAESSTWSGCSGIELAANVHNVTIRDIAIYADDSDGTVAGPAFFAPDSIQNFDFTNNVIGVLPTGADANNQIYRGVIINNGINWGAEQDYDASGQIDNNYFNNTWDTAIIIWYLTSPTDSRTKFVITDNYIINVDGSGMVFERGMNALTVQGNYIDNAGFAGIDNTSGASYLDILQNTVTNTRGFYIKSDNNYDNSTNSEWFPSAGISLGYTAHTNAEFNKVINGAAGVNGIDYAAGSSRAIKVSQNQFGGNGGIAIDIGENNGIETNSHQGDGTGCYLATYHGSPTVTGPSIPIITTATIDGNTLTVEGTMCNGAAIQETSYELQFYVITSGAGDTSTASTTAEPVGGWSFMTNIGNEITGLTYGEGTTYLGRLTNQTNGTFSGTITVSGISAGAQIGAISLSDSNSSGSFYAGQTSEFSATQAVTSTVADYGDAPDSGAGIGTGNYRTLLADNGPSHTSSTSLLIGTNATDEESDALGTGVTTADGDNNDATNDEDSVSNLTIEDTATTFSETIDVTNTTGSTAYLYAWIDWDDSGTFDVDEFVSNGTGTDEQIDIADSAISASIDWSSISGLSSGDQHYMRIRISDTELALGGASGNTEDPRSFGVGGSGEVEDHIISVIATPPPPAIDTDNDGVTDDIDIDDDNDGILDIVELESCKDPTEVSINWDIETERTIASVLSKITKGEQFVTSGPGGNISPAGGAWNFNATSTVSNISDAVSSDAYQQGSFTVGSDPLYVTSSLYYAISVSSFAVYIDDDPAFGSPDILSDGTTYTTANSYLTTGGPSNESSWRRIPLSYGDSYVLQPNTTYYVRFYMPTTNSSHDLLGIGVNLGLTGCSLDPDGDGISNHLDLDSDGDGIPDNIEAQTTLGYIPSNSDSAATYTTNSGLNSAYTATNGLTPENTDTTDDPDYLDLDSDNQGGNDTAEAGLTLSGTVGTNGLDNNYDNGDDFADVNGSFDNTQADNFPDFDGDVSSGGDVDWRDTSVLADYGDAPDVGVGVGGGDYRTIAADNGPFHSVVSATIFIGTTAPDGELDGAQSTNADGDDLDGTDDEDSLGITQLYETSTTFSYNQLVNNSSGSDAYLYAWVDWDNSGTFDKDEFVEGGVSTGDPIVISTGSSNVGTSMLWSTLPALSSMDEYYLRVRISDQILTDSATGSDEDPRSLGNGGSGEVEDQILTVEIEPTLPQVYCAVSSNAETGEQITQLDGYNDNPADGFSGTSIVGDELYSQAGSGQPSKRFELEILAPNQQITYPIGIEIEMRLRNLNAGDGDALFWITDHTNMNGILIGDNAVYLGVDALWNGTNSTVASYSQSPVTIMGNAAGYMTTSYKRYRLKMFVQSDNSVTMQAITMNDDGSIIETSPVVAGDQTFNPNNGIYFAHTGHNNDPAAQRHIFGEITVVATNGLACDYGDAPDANVGTTLGDYKTRAASNGPSHAIDGTIYLGSTGPDSESDAFGDGTDTSFDGSGDDTKGAVPDDEDAITGTLSLSGSDLSFNVACNDFSSGSGDLGATVHAWVDANSNGDFEVSEYTSSTCNDTSATANGTASLSWTGLQRAAGDSYIRLRITNHTLTDADNLGSDDRAYDSVSNGEVEDHPITINPFISGFVFNDDGSGGGTITNGIRDGTETGLGVAVPIIAYNTATTACYVTTSDPTTGAYLIDLPSVGTYKVYEAANETDLISPTCPPTAGTLDSATGTYLNATIGDPATYASSSANIVEVVVTGGSSSTVDFGDFVVNSFDVCATPAYLTQSNGPGTTALNAVNLATGDVTLLDPSITMGAALGYSMHTNTLTAVQGTSTLTLLDGSYTTFSLPITNSTLPSGSNNGDIDDNGILYTHYSGNFYLYDTNPNSETYLTQIGILPTTSLNYADIAFNPIDGQIYAISTADNTLYRFDPTTGTRASLGALVGLPIGPFGAAYFDDQGYFYISENPSPGRIYRIDVLDGSKPAGSYTATLFSQTNASASGNDGARCRYAPVPLDWADAPTVDGYATELTADGPRHQTDVGLPYLGGNTPDNENDGQPTATADGDDTNGLTPDDEDGFSQPTISGILVAGDTLSLTVPVITSSNDNLYAWIDFDASGTFDADERQTVNVTASGNEQLDFTVPADVQLVDTFVRLRICSSGEVCAQPTGSAGDGEVEDHLISLKPVGDLELMLAMDPGVNVTLGIPFNVVVSVENKGATTASDTKVTLPIPTGYSFVKAYAGDGVTEITTYDPVTGELDLGVIGFGFNDYAVIRLAPQDLSAPAINAEIIETGINDIDSTPNNGFGNGEDDTDTVTPAISNIIQPNVCDAPVVFEGGDAYLAANGEYIVTPNTTNQQGYLWSYGYIDLNRPMYAELAVYLGDRSCNTGCPNGIESGADGMTFVLSSDPRDLNAFGAFGGGLGVGDIFGATPVAPSVVFEFDTFDNTYIGATDDAVGGQYIDHTAVYLNGDVYTPDVANTLIPATSVAGGELEDGRYHIAQFEWDPTTNQFTYYMDGVMVGQFTRDIRNDIGNNMVRFGFTGSTGDGYNLQKGCFTKAPNVLGSDLGDAPDTTVGTGINNYTTTYENDGAQHVQADTDDNGFIDLRMGNLWDADLGNLQDIGAIADDNNNFDDEDGVTLVQSATKGENFDITVNVVEDSGRASTGQRLYAWLDFNLDGDWDDAGEQVVADTSAAIGNNSYSVPIPAGAVVGYSYLRVRLCSDVGCDSPIGLANDGEVEDYRVLISDLVGNNQCDLIVQTRLPIAATDYSYNSLDVTVDPITFTDIVNPISITNQSNIANINALGFNRISGLIYGTFTDMSQADRIHHLFVTDKTGTSFIDLGEIRAESATTIRRLQDGESFDFAAGDSLRHTGYSSTSTVLSSPTAGDVTADGNHLIVWRTSWDSLVKIDLNTQTFTTVPLDIATMGGSYGGGSIEVGADLAISSQSGLGYLVDLNGDNLYTVNLSTGAVTAQALTYFGAEPTLDTNGKLQAGALVMDNAVSLYALTNGGNHDTNQDGTIDLNERAVVYRINVMTQEVEYVTASDQGSLQGNDGAGCYDSTDYGDAAASYGQASHAYLDAALDGIADLALGSRWDPEFTQWLSVDASGDDTHGQDDEDLNIPAQIIVETSTTLPIQVVGDGFVNIWVDLNNDGDFADSNEQLINDQAVTTGNNSISVILDAASAEGFNGNTVMRVRLCSSANSCNTFDGAANDGEVEDHWFELLNRIVLSGVVFEDNGVGGATAAHDGLQEGSEVGLGNFTVTVTFNDTGVTGFTSGDVIATDLTSGDGSYQFVIGVDFSGKDLLLDVVKQADWIDISEADVTGITQVTSSSVTDSQMSVNANAGDDISGLDFGKVQEPRMEPDNFSEAEPGKSVLFPHKFTAATAGSVNFSIINTEVEPANDGWNAVLYQDNDCNGVIDGTDAQIVNPVAVSGNTAVCLLSKVFVPADAPLNALYHYDIAADMTFADSAATGHGVTRQVLDKDTVRATFSGAGELKLEKTVRNITQGTAVGMSNQGRPGDVLEYTITFTNVGSGDLTEVSIFDSTPSYTELSQAIDCTSGSVPASLTCIPVTANGTNAVGYEGEVRWDMTGSLLAGEQGTVVYLVVIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4I1</accession>
    <name>D0Z4I1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000439</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304369.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000439"/>
    <dbReference type="EnsemblBacteria" id="EEZ39419">
        <property type="protein sequence ID" value="EEZ39419"/>
        <property type="gene ID" value="VDA_000439"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031JFP">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1846909at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019406" evidence="1">
        <location>
            <begin position="19"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="197" mass="22228" checksum="EB3595ADF9CF0FC4" modified="2010-01-19" version="1">MYRIIISSLFAVFLVACAQSTLTSAWVDRTYTKTPIKSMLVIAMSDNLRVRRIFEDGMVQKLKAQGVNAIASSQVYPDKLPSKEIIGNYVKKNNIQTVFVGQLINIEDKNIRYPGNGFSNSVTFTNYYSSSYSYIYDDSYTVSYEFVNIEFTLFDTASHKPIWSTSSESVDPTNINNISDELAGILVSNMKDSRLIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4K9</accession>
    <name>D0Z4K9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">5'-nucleotidase yjjG</fullName>
            <ecNumber evidence="1">3.1.3.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000467</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.3.5" evidence="1"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304443.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000467"/>
    <dbReference type="EnsemblBacteria" id="EEZ39447">
        <property type="protein sequence ID" value="EEZ39447"/>
        <property type="gene ID" value="VDA_000467"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1011">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1204073at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106411">
        <property type="term" value="F:XMP 5'-nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011951">
        <property type="entry name" value="HAD-SF_hydro_IA_YjjG/PynA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00413">
        <property type="entry name" value="HADHALOGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02254">
        <property type="entry name" value="YjjG/YfnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="224" mass="25591" checksum="E49065B542F233E4" modified="2010-01-19" version="1">MKYQWILFDADETLFHFDAFKGLQLMFSRHNIVFTEDDFLEYQQLNKPLWINYQEGKITASELKTQRFQQWSAKSGLSTEQLNRDFLNAMADICTLLPHAKELIDSLKGHVKLGIITNGFTDLQQIRLEKTGLGDAFDLLVISEQVGYPKPAKEIFDYALKHMGQTEPNHVLMVGDNIDTDILGGINAGMETCWLNVDGKIQPNHIKPSLCVQSLLDLKQYLLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4R8</accession>
    <name>D0Z4R8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Potassium uptake protein integral membrane component KtrB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_000526</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304629.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000526"/>
    <dbReference type="EnsemblBacteria" id="EEZ39506">
        <property type="protein sequence ID" value="EEZ39506"/>
        <property type="gene ID" value="VDA_000526"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0168">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="756220at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015379">
        <property type="term" value="F:potassium:chloride symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003445">
        <property type="entry name" value="Cat_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004772">
        <property type="entry name" value="TrkH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02386">
        <property type="entry name" value="TrkH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00933">
        <property type="entry name" value="2a38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0630">Potassium</keyword>
    <keyword evidence="4" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="27"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="86"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="201"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="240"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="307"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="361"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="387"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="417"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ39506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="455" mass="49234" checksum="C0DCAD2DFDE352A7" modified="2010-01-19" version="1">MNRLPNKGVFVPIKTEKQGKGWSEPRIIVFSFLAILVPAAILLTLPVFSVSGLDFTDALFTATSAISVTGLGVVDTGTHFTLSGKILLMILMQIGGLGQMTLSALLLYMFGLRLSLKQQSLAKEQLGQSSSVNLRRLIKHIITFVLICEAIGVVLLSIRFVPQMGWETGLFTALFHSISAFNNAGFSVFSNGLVPYVGDPLVIITIAMLFILGGLGFTVVSDIRRNIRRGISHLALHSKIMLTATPILLLAGTLFIWLLEKDNPKTLGHLSEGTQWLAAFFQSATARTAGFNSVDISQFTDPTMLIMIILMLIGAGSTSTGGGIKVSTFVVAITATWTFLRQQNFVTLFKRSVPWPTVTKCLAIVVVSGFIIATATFSLMITEKSPFLQTLFETISAFATVGVTAGLTAHLTEPGKYIMIVVMIIGRIGPLTLVYLLARPKPTLLKYPEDNVFAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4S8</accession>
    <name>D0Z4S8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Alkaline phosphatase</fullName>
            <ecNumber evidence="8">3.1.3.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_000536</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the alkaline phosphatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.1" evidence="8"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304656.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000536"/>
    <dbReference type="EnsemblBacteria" id="EEZ39516">
        <property type="protein sequence ID" value="EEZ39516"/>
        <property type="gene ID" value="VDA_000536"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1785">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="585847at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004035">
        <property type="term" value="F:alkaline phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd16012">
        <property type="entry name" value="ALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001952">
        <property type="entry name" value="Alkaline_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018299">
        <property type="entry name" value="Alkaline_phosphatase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042085">
        <property type="entry name" value="Ap_crown"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11596">
        <property type="entry name" value="PTHR11596"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00245">
        <property type="entry name" value="Alk_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00113">
        <property type="entry name" value="ALKPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00098">
        <property type="entry name" value="alkPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00123">
        <property type="entry name" value="ALKALINE_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003020013" evidence="7">
        <location>
            <begin position="24"/>
            <end position="525"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ39516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="525" mass="57336" checksum="6C1828977A0A1A12" modified="2010-01-19" version="1">MNKYIKPLATIIAASTLSLNAHSAEIKNVILMIGDGMGPQQVGLLESYAKLAPNSIYKGKPTALYQLAQDGVIGSSLTHPDDAIVVDSACSATMLATGISTGSEVIGIDPDGNAIETVLEKAKRMGKATGLVSDTRMTHATPAAFAAHQPHRSLENEIASDMLATQVDVLLSGGLRNWIPQSANQQGEIYQQLQTLTHGDVGLKSKRKDERNLLLEAKDLGYSLVFNKQMLEEATGSKVLGLFASSGMADGIEYSKTKEDPARTQPTLREMTEKALEVLAKNDKGFFLMVEGGQIDWAGHSNDAGTMLHEMLKFDNTIDAVYQWAKGRDDTLVIVTADHETGSFGFSYSGYQLPEPQKRSGEAFAQRDYAPNFNFGAFTILDGLYQQKKTYSGMLTEFGQLPKDKQTAKQLMKIVNNNSEFAITEAQAKAVLTDKTNPYHVDGHSYLSESTIPAIHDFDAFYPYNDRTNLLARVQGTKQNIVWGTGTHTHTPVNVFAWGPSDVILPVSKILHHSELGEYIKSQVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z541</accession>
    <name>D0Z541_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Peyer's patch-specific virulence factor GipA (Transposase)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">VDA_000091</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the transposase 35 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the N-terminal section; belongs to the transposase 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39075">
        <property type="protein sequence ID" value="EEZ39075"/>
        <property type="gene ID" value="VDA_000091"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0675">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032196">
        <property type="term" value="P:transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001959">
        <property type="entry name" value="Transposase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010095">
        <property type="entry name" value="Transposase_IS605_OrfB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021027">
        <property type="entry name" value="Transposase_put_HTH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12323">
        <property type="entry name" value="HTH_OrfB_IS605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01385">
        <property type="entry name" value="OrfB_IS605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01766">
        <property type="entry name" value="tspaseT_teng_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0815">Transposition</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="HTH_OrfB_IS605" evidence="12">
        <location>
            <begin position="2"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="OrfB_IS605" evidence="11">
        <location>
            <begin position="145"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF12323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ39075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="283" mass="32335" checksum="60779FC8968B58EA" modified="2010-01-19" version="1">MLAHTFGCVRFVYNSALSFSKERYEQGNKTNFNDWNKNLTTLEKEADFSWLKNVSSGPLQQSFRHLDKVFFKSEFGYPKFKNKRGKQPACYMANAFKFNAEIKQITLAKLKNPCKVTLSIPFNSSPSSVYVSKTKTGKDFISMLVETEIQPLPIANKTVGVDVGIKSLAACSDGSIFNNPKYTKKYEKKLAKAQRKLSKKAKGSNNFNKQRIIVAKIHEKIANCRVDFTRKMTTKLINENQVIYTESLRVKNMIKNKKLAKEISDANFGEIVRQLEYQAAWYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z553</accession>
    <name>D0Z553_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein TadG associated with Flp pilus assembly</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000103</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000103"/>
    <dbReference type="EnsemblBacteria" id="EEZ39087">
        <property type="protein sequence ID" value="EEZ39087"/>
        <property type="gene ID" value="VDA_000103"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4961">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028087">
        <property type="entry name" value="Tad_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13400">
        <property type="entry name" value="Tad"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="2">
        <location>
            <begin position="163"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="436" mass="49202" checksum="C67FD900B8A39AE2" modified="2010-01-19" version="1">MKLKKAQQGHASILFAIMIPVLFGIFTLASDGARAIQTKARIEDATEAASLAIAAHNDPNVNSDGLGSGSKVNRRIATDYLKAYITDIDSISSLKIYRRNCEDIPECSSGLNKGKSRFFEYEVEALTTQNSWFPGNNVISGFGDTFSTRGHSLARKYQSEAVDVVFAADFSKSMEEPWTGGRQKYKDLVRVINDVTSELEKFNNINIADKKNQNTIGISPYNSNTYSKFDNYNSCFMKQDYFEKNSRDHRKKKYVDIKRTLNNIFIEKGNDSCGFKSDDPDAVFHDIYLTNDFDTFNKEIRKFRPGNGTASCQGIIRSAQMLRKGTNSRRLLIIISDGNDWYYPYSGYKETDKEIANKLVNAGMCNKIRETLNLDKTPSGQEIKTRIAVIGFDYDANKNKALLNCAGEDNVFKAQYRDELLDQILSLITEEIGHLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-12-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z554</accession>
    <name>D0Z554_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Lipoprotein OmpA family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_000104</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306859.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000104"/>
    <dbReference type="EnsemblBacteria" id="EEZ39088">
        <property type="protein sequence ID" value="EEZ39088"/>
        <property type="gene ID" value="VDA_000104"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2885">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2018797at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07185">
        <property type="entry name" value="OmpA_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006664">
        <property type="entry name" value="OMP_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006665">
        <property type="entry name" value="OmpA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036737">
        <property type="entry name" value="OmpA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00691">
        <property type="entry name" value="OmpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01021">
        <property type="entry name" value="OMPADOMAIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103088">
        <property type="entry name" value="SSF103088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51123">
        <property type="entry name" value="OMPA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="1 2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019440" evidence="3">
        <location>
            <begin position="21"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="OmpA-like" evidence="4">
        <location>
            <begin position="97"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="210" mass="23798" checksum="CE45AAB348D521AD" modified="2010-01-19" version="1">MKKILIFISILLISPIDSYAKNSDDIDNSILLFCNTGNGKYQKEVTVERGDRIYLNQGSYSQIQQYDIVDVDKELLKNILGKMNSGEKCFEYLLSNASIERDDTTARVYFNFDNSKLTSASIYILNKLIENVKASKSNYLIEGHTDSVGTTSYNKDLGYRRAKSVIEFFVGNGVNRSQLQGISEGELKPLETNDTSIGRSYNRRVEIKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5B8</accession>
    <name>D0Z5B8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000025</name>
        <name evidence="2" type="ORF">VDA_000028</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000005">
        <property type="protein sequence ID" value="EEZ39040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="ADBS01000005">
        <property type="protein sequence ID" value="EEZ39043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005307051.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000005.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39040">
        <property type="protein sequence ID" value="EEZ39040"/>
        <property type="gene ID" value="VDA_000025"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39043">
        <property type="protein sequence ID" value="EEZ39043"/>
        <property type="gene ID" value="VDA_000028"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="64" mass="7277" checksum="478D83B7FCA80434" modified="2010-01-19" version="1">MDNVIQLLNTQYDIAPPKDHDEEIALIYQYLIDKFGDTSTTAFKLHEVLISLAHIAERDGATPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5F1</accession>
    <name>D0Z5F1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000058</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000005">
        <property type="protein sequence ID" value="EEZ39073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000058"/>
    <dbReference type="EnsemblBacteria" id="EEZ39073">
        <property type="protein sequence ID" value="EEZ39073"/>
        <property type="gene ID" value="VDA_000058"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021352">
        <property type="entry name" value="DUF2971"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11185">
        <property type="entry name" value="DUF2971"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="326" mass="38502" checksum="19BAB8DF1CAAF649" modified="2010-01-19" version="1">MNRFLYKYMPMRASFFEDLMIRATPVIALNDPFEGAFSVQQIKDLDRNLTDFYQQNGKQTDKFDDGELDDIAGVIQMDFFDLGIISLTEDYNNPLMWAHYADEHKGCVVEFDFSKPFFMDSIFESNGRPSRFGKDYLGHTYEYPEKVNYRRVMPDFSRKEQFVPEDLSEFHGKKFNRTILYTKSNDWIYEKEQRIVVPLCHADSIICRDAEDVRSACDKDKNIKVVELENDKIQIYFPYEYEMHEDVGDQSIKDEIYRLTVDYDEPAVHLFRLNPKAISGVYFGCKSKHCDALDKINSNVSLRHLGHKYKMERNIILYELDNVKLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVK1</accession>
    <name>D0YVK1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">VOC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001581</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40555">
        <property type="protein sequence ID" value="EEZ40555"/>
        <property type="gene ID" value="VDA_001581"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="81" mass="8420" checksum="EE2E225B3D574DC7" modified="2010-01-19" version="1">MAPKGAETTISLVPPFGGMAAGSVQGLVVQTDDLLSTHKELSQRGVALSEIITIMGGRFATFSDPDGNGWVLIEPLSTMMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVN5</accession>
    <name>D0YVN5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycerate kinase</fullName>
            <ecNumber evidence="5">2.7.1.31</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001200</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycerate kinase type-1 family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.31" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297625.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001200"/>
    <dbReference type="EnsemblBacteria" id="EEZ40178">
        <property type="protein sequence ID" value="EEZ40178"/>
        <property type="gene ID" value="VDA_001200"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1929">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1292731at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008887">
        <property type="term" value="F:glycerate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031388">
        <property type="term" value="P:organic acid phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1510.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018193">
        <property type="entry name" value="Glyc_kinase_flavodox-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004381">
        <property type="entry name" value="Glycerate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018197">
        <property type="entry name" value="Glycerate_kinase_RE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036129">
        <property type="entry name" value="Glycerate_kinase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21599">
        <property type="entry name" value="PTHR21599"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02595">
        <property type="entry name" value="Gly_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006078">
        <property type="entry name" value="GlxK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110738">
        <property type="entry name" value="SSF110738"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00045">
        <property type="entry name" value="TIGR00045"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 5" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR006078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="377" mass="38922" checksum="63AB14145254E175" modified="2010-01-19" version="1">MKIVIAPDSYKESLTAMEVACAIEAGFRKVLPEAEYIKLPMADGGEGTVQSLVDATGGEIITARVTGPLGEQVDGFYGLMGDGHTAVIEMAAASGLHLVAPEQRNPLQTTTFGTGELILAALNQGAKHIIVGIGGSATNDGGIGMAQALGIRMLDSQGKEIGYGGGALARLATIDMSGLDPRLAQVELEVACDVDNPLCGEKGASQVFGPQKGATPEMVAQLDANLAHYAELIKTQLGADVKEMAGAGAAGGLGAALLGLLQARLRPGIEIVMDAVNLADVVQDADLVITGEGRIDSQTIHGKTPIGVARTAKRFNKSVIGISGCLSNDCDVVHEHGIDAVFSVVPRSVTLAEALRDAAFNVELTARNVAAMYRLSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVR1</accession>
    <name>D0YVR1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chromosome segregation ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002002</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002002"/>
    <dbReference type="EnsemblBacteria" id="EEZ40970">
        <property type="protein sequence ID" value="EEZ40970"/>
        <property type="gene ID" value="VDA_002002"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1196">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018306">
        <property type="entry name" value="Phage_T5_Orf172_DNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10544">
        <property type="entry name" value="T5orf172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00974">
        <property type="entry name" value="T5orf172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T5orf172" evidence="2">
        <location>
            <begin position="127"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="13"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="262" mass="30389" checksum="FFCF500333905EFB" modified="2010-01-19" version="1">MIIISNKYLQFKIEELRLTHEYKEKKQREKEEQAEIKAQMREEAKVEAEIKKAEQEAIKEEARFSKALVIARKQLESANDEARSKLEEQITQLQADLEAAEQKHQRAQSMAEQTKQGYVYIISNIGSFGENVYKIGMTRRLEPMDRVKELGDASVPFSFDVHAMIHTNDAPSLEKELHRIFDNNRLNMVNRRKEFFQVALSDIKQAVKKFDIDDAEFIETAVAQDFNETKAMRKQAELKEAMELGAITDITKTKQPEFAECI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVT5</accession>
    <name>D0YVT5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002016</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002016"/>
    <dbReference type="EnsemblBacteria" id="EEZ40984">
        <property type="protein sequence ID" value="EEZ40984"/>
        <property type="gene ID" value="VDA_002016"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG503217S">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020979">
        <property type="entry name" value="Uncharacterised_A0KLC6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12290">
        <property type="entry name" value="DUF3802"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="96" mass="10997" checksum="935255EBAE00B1CF" modified="2010-01-19" version="1">MALFESAQKEHSGEQTIEDIVMDLIATHIMAVFEQNPELESDVRFQLLKDADAVVADLNEVLAGVWRYYPTNQQIRFLEEYIGLVKNLFDTAISSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVZ8</accession>
    <name>D0YVZ8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Protease insulinase family/protease insulinase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_001303</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M16 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297836.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001303"/>
    <dbReference type="EnsemblBacteria" id="EEZ40278">
        <property type="protein sequence ID" value="EEZ40278"/>
        <property type="gene ID" value="VDA_001303"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0612">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1188251at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="SSF63411"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019832" evidence="3">
        <location>
            <begin position="20"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16" evidence="4">
        <location>
            <begin position="59"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16_C" evidence="5">
        <location>
            <begin position="216"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16" evidence="4">
        <location>
            <begin position="535"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16_C" evidence="5">
        <location>
            <begin position="682"/>
            <end position="854"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="948" mass="105238" checksum="5A1B24CDDB1BED95" modified="2010-01-19" version="1">MQKWILPLALLSVTNTTWAAKQSDVPLPKGVSFIEQVKPEPGKAVIPFRKYELSNGLTVILHQDKSDPLVHVDMTYHVGSAREEVGKSGFAHFFEHMMFQGSKHVGDQEHFRLITEAGGTLNGSTNRDRTNYYETVPANQLEKVLWLESDRMGFLLDAVSQKKFEIQRSTVKNERAERYENRPYGLVYERMGEALFPRDHPYSWQTIGYVADLDRVDVNDLKAFFLRWYGPNNATLTIGGDIDIAQTLDWVEKYFGSIPRGPEVNNAPKQPVTLKADRYITLEDKVQQPMLMMGWPTSYRGAKDEASLDMLAQIIGDGTNSLLYQKLVKTGQVVDAGAFNDCAELACTMYVYAIGPSGEKGNLKSIRGKVMEIVNSLEKQGVKQQAVDEIKGVAESSAIFGLQSVSGKVAQLAAYQTFYGDPNHLGVELDNIRKVSPSSIEAAYNQYIYQHPNVTLSVVPQGKLDLVAAKTNFTPEPRKIPEHQKINDDQLTLRTAKDNFDRSIMPQPSKPVEAMMPSLYDVTLANGIKILGTQYDETPTVELQLVVPAGRRYEAEGKAGLAQLTAAMMNEATTKASAEHIASELDKLGSSVSFDAGLYGTTITLSSLAKNLKPTLAILEQRLFHPAFAQADFDRLKKLALEGLVYEHQRPEWLAGQATRDVMFKGTVFSQAPEGTKASIESITLADVKDFYQRYYTPNGADMVVVGDIKPQTLQQDLASLGQWKGQAAPTYHTPKLPSIEKPAIWMVDKPGAPQTIIRLVRQGLPYDATGELYKTQLANFNLAGNFNSRINLNLREDKGYTYGAGGYLTGGKELGLATFYAQVRADASLAATKEFLAELKKMSQGGLTDKEMKFMRLAVGQQDALKYETPAKKAQLLGQMLTYSLPKDFVEQRNKIAATISKSELDKLAKKWFNPQDYQVIVVGDVAKLKPQFATLGLPIHVIKPQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW53</accession>
    <name>D0YW53_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RecBCD enzyme subunit RecC</fullName>
            <ecNumber evidence="6">3.1.11.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Exonuclease V subunit RecC</fullName>
            <shortName evidence="6">ExoV subunit RecC</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Helicase/nuclease RecBCD subunit RecC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">recC</name>
        <name evidence="8" type="ORF">VDA_001335</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>Exonucleolytic cleavage (in the presence of ATP) in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides.</text>
            <dbReference type="EC" id="3.1.11.5"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="6">Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the RecC family.</text>
    </comment>
    <dbReference type="EC" id="3.1.11.5" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297872.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001335"/>
    <dbReference type="EnsemblBacteria" id="EEZ40310">
        <property type="protein sequence ID" value="EEZ40310"/>
        <property type="gene ID" value="VDA_001335"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1330">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1320159at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:exodeoxyribonuclease V complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="term" value="F:DNA helicase activity"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008854">
        <property type="term" value="F:exodeoxyribonuclease V activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.160">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01486">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013986">
        <property type="entry name" value="DExx_box_DNA_helicase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006697">
        <property type="entry name" value="RecC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041500">
        <property type="entry name" value="RecC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17946">
        <property type="entry name" value="RecC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000980">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01450">
        <property type="entry name" value="recC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 6 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RecC_C" evidence="7">
        <location>
            <begin position="842"/>
            <end position="1076"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ40310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="1151" mass="131575" checksum="ACFD1FA2E0AB6C13" modified="2010-01-19" version="1">MFTIYHSNQLDLLKSLLVELIRLDPLDNPFTPEQILVQSPGMSQWLKLELAQSMGIAANITFPLPATFIWDMFTQVLSDVPKRSAFNKESMTWKLMQILPDQLERPEFEPLQRYLEQDAQGQKRYQLAEKIADIFDQYLVYRPEWIQAWEGGEIDPEICADHPWQPLLWQALYDHTLSLGQSPYHRANLYQHFIETLENYSQTGTALPQGLPKRLFVFGISALPPRYLDALAALGKHIDVHLMFTNPCRHYWGDVRDRKYIARLAAKHRQQLQVQGERSELGAQVSTLKGSVDDNVFDETQEASVGNTLLASLGKLGRDNLYLMSELEAFDVEAFVDIEHDSLLHAIQADILNLEDRIQDHLTENSHHKLAINSQDHSLTIHACHSAMREVEVLHDNILAMLEQDPSLTPRDIVVMVADINNYSPYIQAVFGNAPGDRYIPFSISDRSADQENPILLAFLKLIALPESRCQASELLELLEVPAVMARFGFNADSFEQIKQWIEEVGIRWGLDDSTACEFSLPKQQQNTWLFGLQRMLLGYAMPQELGLYQGTLAYDEVQGMDAVLAGQLGLFIEKLMHYRMQLAQEQGVTEWTLILNQLLDDFFSVELEGERVLHLIRDKLQQLEQQLDDAGFGEKITPVVMRDYLMGKLSGERVSQRFLAGQVNFCTLMPMRSIPFKVVCLLGMNDGVYPRSIAPEGFDLMSHDHRAGDRSRRDDDRYLFLEAIQSAQQKLYISYVGRSIQDNSEKMPSVLVSELLEYCGQGYCLEGDEALTADDSAERLVKSRIYTHPLTPFSPQAFLGEQPSFAAEWLPAANREQIITSHFYQQPLEPELVTPHIPQLLELSELVRFWRLPVQYFFNRRLKVFFDPSQGALADDEPFSLDGLGRYQLREALLSEFLNHQVMTQVSQGQLTKDQLFERFTAYQNAAGGLPLAEFGQLTLLEERAQIEQLAEKVVQLMDHEQPDVEVNLLVSIAERQVQLQGWLKQYYQQGLIRYRPGKIRSNDILSGWIEHLCLACAGIEKPTHLIGVDQHLVFNPLSREVAIPQLEALLEHYFQGLVQPLPYFPRTILAGLEAGRDKQGNWLTDEASIEKIFNKMAEGFNGVYMFDGEGINHYIARVWPEWSQELAQEVYEMAEKLLKPAISQLSEVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW67</accession>
    <name>D0YW67_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nitric-oxide reductase quinol-dependent</fullName>
            <ecNumber evidence="2">1.7.99.7</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001352</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.7.99.7" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297904.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001352"/>
    <dbReference type="EnsemblBacteria" id="EEZ40327">
        <property type="protein sequence ID" value="EEZ40327"/>
        <property type="gene ID" value="VDA_001352"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3256">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="133514at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004129">
        <property type="term" value="F:cytochrome-c oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009060">
        <property type="term" value="P:aerobic respiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.210.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036927">
        <property type="entry name" value="Cyt_c_oxase-like_su1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000883">
        <property type="entry name" value="Cyt_C_Oxase_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10422">
        <property type="entry name" value="PTHR10422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00115">
        <property type="entry name" value="COX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81442">
        <property type="entry name" value="SSF81442"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="230"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="283"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="328"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="362"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="411"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="443"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="484"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="515"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="544"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="585"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="628"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="667"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="723"/>
            <end position="741"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="754" mass="84389" checksum="A22B78C3702CBBCF" modified="2010-01-19" version="1">MSKLKLSALALLIVCFASFTVLLSLGSDIYREAPPIPTQIKTTSGQIIFTQQNIEQGEMVWRSMGGHQLGSIWGHGSYVAPDWTADWLHRENQNWLNLLAQKQFSLPYSALTRPQQAALQQQVTDEMRKNTYNPQTGVITLSPLRAQAIAQLEQHYIALFGDDSSLNQLREDYAIKTNTLPSLERRQELNAFLFWGAWAAITERPDQNYTYTNNWPYDPALGNTPTSDNVVWSILSIVVLLAGIGALAWYQAAQRHDPLPKLPAQDPLFGQKPTPSQKAVGKYFITAIGLFLLQIVLGGITAHYGVEGQDFYGIPLAKILPYSLTRTWHTQLAVFWIATAWLGTGLYIATSLSKHEPKYQKLGVNLLWVALVFVVLGSMAGEWLAIQQYFDLDTSYIFGHQGMEYIDLGRLWQVLLLIGLLLWLTLVTTAIRPALSERSDNRPVIWVLYASCVAIGLFYGAGLFQGKHTNLAMAEYWRWWVVHLWVEGFFETFATSVISLMFVRLGLIRAKSANSAVLFTTVIFLTGGLLGTLHHLYFTGTPTAVIAWGAIFSALEVVPLALIGFEAVESYRLRKATPWMQRYHWAIMFFVATAFWNLVGAGILGFLINPPIALYYIQGLNTTATHAHGAFMGVYGMLGIGLMLTCLRGLAGQNKAWNDKTLKYTFWCLNIGLAAMIFCSLLPVGLTQFFAVIEHGYWYARTPEVLHSPLVQDLIWARMPGDMLFGLGGVLMGWFLLQLIVSKVKHNSTVTNNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW68</accession>
    <name>D0YW68_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Anaerobic nitric oxide reductase transcription regulator NorR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_001353</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297906.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001353"/>
    <dbReference type="EnsemblBacteria" id="EEZ40328">
        <property type="protein sequence ID" value="EEZ40328"/>
        <property type="gene ID" value="VDA_001353"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3604">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="123059at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025943">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025944">
        <property type="entry name" value="Sigma_54_int_dom_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00158">
        <property type="entry name" value="Sigma54_activat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00676">
        <property type="entry name" value="SIGMA54_INTERACT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00688">
        <property type="entry name" value="SIGMA54_INTERACT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50045">
        <property type="entry name" value="SIGMA54_INTERACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="6">
        <location>
            <begin position="184"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="506" mass="57121" checksum="1D5FBB6650399C39" modified="2010-01-19" version="1">MNSIELAQIARLVTLHSSHAHGLQTCLYHLTNILGCDAAALLLYRQDRLIPVATVGLNQDVMGRQFKLSEHPRFEIVAKVQDLICFHAADELPDPFDGLLLNCPEPHIHACLGLPLLYGREFIGVLSLEALQPNYFHRFSQDSLRVLMSTFALALYCYQQQQLLEVQVFGGKSKPISKQMVKEMVGESDAIQQLKHSIQVVAQSELNVLIEGETGVGKELVAEKIHRYSNRNQQPMVYLNCAALPENLAESELFGHIKGAFTGAIQNRKGKFEQADGGTLFLDEIGELSLNLQAKLLRVLQYGDLQRLGDDQHRVVDVRVIAATNKRLAQAVQDQTFRADLYHRLSVYPIEVPPLRDRQSDIVLLAGYFLELSRCRLGLSVLRLAPSCLPLLEQYSWPGNIRELEHQLRRAALIARSEQGIDYVTIQPEYFNFTQQPSVTENTRQAPKRGDKVTIVGSLRENTDQFQRQLIEQQLTELQGNWAKTAQALQLDRANLHRLAKRLGLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW69</accession>
    <name>D0YW69_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001354</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297907.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001354"/>
    <dbReference type="EnsemblBacteria" id="EEZ40329">
        <property type="protein sequence ID" value="EEZ40329"/>
        <property type="gene ID" value="VDA_001354"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502Z9WC">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="632187at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021936">
        <property type="entry name" value="DUF3549"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12069">
        <property type="entry name" value="DUF3549"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="346" mass="39250" checksum="459DBE0CA842C67C" modified="2010-01-19" version="1">MDQFHTLTQLLDNAQCQYAIYDLGRRVTQLDVDQFKAVEENRQPYPWPLQQHANLALSFWQPNHTPWIWFLRLPLDERGLLKQAAVGDFIKYVIEAMGATLNRTPSEEEQKKLANNPYTFKPNDDKMAMFHGKLRSQLQLEPSQYYAGAQQYLTGELGWDNWQQLGLQGLADVCSRLSQENNATLVRKAINHLPMTPLYALLGCLEHIELPDNLTSRISERLATEMAQSAPDIFLISALIRALSGSNETVLKGEIAQLLAQPHLCHPEILIAIAGRCWQGLNQPNNAELFLLRLAQSQNQALFNQLFSDLVMLPMLRGIMLQLLHGQANPELIQAIAELQQHARGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW97</accession>
    <name>D0YW97_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 10">Pyruvate dehydrogenase E1 component</fullName>
            <ecNumber evidence="4 10">1.2.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">VDA_001194</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 10">Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>(R)-N(6)-lipoyl-L-lysyl-[dihydrolipoyllysine-residue acetyltransferase] + H(+) + pyruvate = (R)-N(6)-(S(8)-acetyldihydrolipoyl)-L-lysyl-[dihydrolipoyllysine-residue acetyltransferase] + CO2</text>
            <dbReference type="Rhea" id="RHEA:19189"/>
            <dbReference type="Rhea" id="RHEA-COMP:10480"/>
            <dbReference type="Rhea" id="RHEA-COMP:10481"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83111"/>
            <dbReference type="EC" id="1.2.4.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).</text>
    </comment>
    <dbReference type="EC" id="1.2.4.1" evidence="4 10"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297613.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001194"/>
    <dbReference type="EnsemblBacteria" id="EEZ40172">
        <property type="protein sequence ID" value="EEZ40172"/>
        <property type="gene ID" value="VDA_001194"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="49937at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004739">
        <property type="term" value="F:pyruvate dehydrogenase (acetyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02017">
        <property type="entry name" value="TPP_E1_EcPDC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035807">
        <property type="entry name" value="PDC_E1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004660">
        <property type="entry name" value="PDH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041621">
        <property type="entry name" value="PDH_E1_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005474">
        <property type="entry name" value="Transketolase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43825:SF3">
        <property type="entry name" value="PTHR43825:SF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17831">
        <property type="entry name" value="PDH_E1_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00456">
        <property type="entry name" value="Transketolase_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000156">
        <property type="entry name" value="Pyruvate_dh_E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00759">
        <property type="entry name" value="aceE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 10 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10 14" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="TRANSKETOLASE_1" evidence="12">
        <location>
            <begin position="104"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="TRANSKETOLASE_1" evidence="12">
        <location>
            <begin position="361"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="domain" description="PDH_E1_M" evidence="13">
        <location>
            <begin position="490"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="230"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="260"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="262"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00033635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR000156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000156-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF17831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEZ40172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="886" mass="99293" checksum="A27A0C885FB27FC5" modified="2010-01-19" version="1">MSEVMKHDVDALETQEWLAALESVVREEGLERAQYLLEQVLDKARLDGVDMPTGITTNYINTIPADKEPAYPGDTTLERRIRSIIRWNAIMIVLRASKKDLDLGGHMASYQSASAFYEVCFNHFFRAANDVDGGDLVYYQGHISPGIYSRAFVEGRLSEEQLDNFRQEVDGKGIPSYPHPKLMPEFWQFPTVSMGLGPISAIYQARFLKYLAGRGLKDTSNQRVYAFLGDGEMDEPESRGAISFAAREKLDNLCFLINCNLQRLDGPVMGNGKIIQELEGLFKGAGWNVVKVIWGNNWDSLLAKDTSGKLLQLMNETIDGDYQTFKSKDGAYVREHFFGKYPETAALVADMTDDEIFALKRGGHDSSKLFAAFNNAKETQGKPTVILAKTIKGYGMGDAAEGKNIAHGVKKMDMTHVQHLRDRLGLQDLVSDEDMKTLPYLKLEEGSAEYNYLHARRDALHGYTPKRLRNFTNELAIPALDEFKPLLDEQKRDISTTMAFVRILNILLKDKGIGKNIVPIIADEARTFGMEGLFRQVGIYNPHGQEYTPEDRGVVSYYKEATSGQVLQEGINELGAMSSWVAAATSYSTNDLPMIPFYIYYSMFGFQRVGDMAWMAGDQQARGFLLGATAGRTTLNGEGLQHEDGHSHVLANTVPNCISYDPTFAYELAVIMQDGIRRMYGEQENVFYYLTTMNENYAMPAMPEGAEEGIRKGIYKLESYAGNNKVQLMSSGTIMNEVRKAAQILSEEYGVASDVYSVTSFNELTRDGQNVERFNMLHPEAEQQVPYITQVMGTEPAIAATDYMKNYAEQVRAFMPSESYKVLGTDGFGRSDSRENLRRHFEVNASYVVVAALNELAKRGDIEKSVVADAIKKFDIDTEKMNPLYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWD4</accession>
    <name>D0YWD4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">Phosphoribosylformylglycinamidine cyclo-ligase</fullName>
            <ecNumber evidence="3 12">6.3.3.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 12">AIR synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11 12">AIRS</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9 12">Phosphoribosyl-aminoimidazole synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">purM</name>
        <name evidence="15" type="ORF">VDA_001404</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8 12">
            <text>2-formamido-N(1)-(5-O-phospho-beta-D-ribosyl)acetamidine + ATP = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:23032"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:137981"/>
            <dbReference type="ChEBI" id="CHEBI:147287"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.3.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 12">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the AIR synthase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.3.1" evidence="3 12"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298008.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001404"/>
    <dbReference type="EnsemblBacteria" id="EEZ40379">
        <property type="protein sequence ID" value="EEZ40379"/>
        <property type="gene ID" value="VDA_001404"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0150">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="923547at2"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00129"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004641">
        <property type="term" value="F:phosphoribosylformylglycinamidine cyclo-ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02196">
        <property type="entry name" value="PurM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.650.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00741">
        <property type="entry name" value="AIRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010918">
        <property type="entry name" value="PurM-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036676">
        <property type="entry name" value="PurM-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016188">
        <property type="entry name" value="PurM-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036921">
        <property type="entry name" value="PurM-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004733">
        <property type="entry name" value="PurM_cligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10520">
        <property type="entry name" value="PTHR10520"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00586">
        <property type="entry name" value="AIRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02769">
        <property type="entry name" value="AIRS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55326">
        <property type="entry name" value="SSF55326"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56042">
        <property type="entry name" value="SSF56042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00878">
        <property type="entry name" value="purM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 12 15" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AIRS" evidence="13">
        <location>
            <begin position="62"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="AIRS_C" evidence="14">
        <location>
            <begin position="178"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00033093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EEZ40379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="346" mass="37071" checksum="401A16E7FE16DACA" modified="2010-01-19" version="1">MSDKNSSLSYKDAGVDIDAGNALVDRIKGVVKRTHRSEVMGNIGGFGALCALPTKYKEPVLVSGTDGVGTKLRLAMDLKQHDTIGIDLVAMCVNDLIVQGAEPLFFLDYYATGKLDVDTAASVVTGIGEGCLQSGCALIGGETAEMPGMYHGEDYDVAGFCVGVVEKAHIIDGTKVAAGDALIAVGSSGPHSNGYSLIRKIIEVSQADLNQELHGRTLAEHLLTPTKIYVKSVLNLMEQCDIHAISHITGGGFWENIPRVLPDNTKAVVDGSSWQWPAIFNWLQEAGNVDTYEMYRTFNCGVGLVIALPQQQAQQAIDILNAQGENAWLLGHIDQATDGEEQVEIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWP5</accession>
    <name>D0YWP5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 2">Peptidyl-tRNA hydrolase</fullName>
            <shortName evidence="1">PTH</shortName>
            <ecNumber evidence="1 2">3.1.1.29</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pth</name>
        <name evidence="4" type="ORF">VDA_001441</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 2">
            <text>an N-acyl-L-alpha-aminoacyl-tRNA + H2O = a tRNA + an N-acyl-L-amino acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:54448"/>
            <dbReference type="Rhea" id="RHEA-COMP:10123"/>
            <dbReference type="Rhea" id="RHEA-COMP:13883"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:59874"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:138191"/>
            <dbReference type="EC" id="3.1.1.29"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the PTH family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.29" evidence="1 2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298068.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001441"/>
    <dbReference type="EnsemblBacteria" id="EEZ40415">
        <property type="protein sequence ID" value="EEZ40415"/>
        <property type="gene ID" value="VDA_001441"/>
    </dbReference>
    <dbReference type="GeneID" id="57339605"/>
    <dbReference type="eggNOG" id="COG0193">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1676462at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004045">
        <property type="term" value="F:aminoacyl-tRNA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00462">
        <property type="entry name" value="PTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00083">
        <property type="entry name" value="Pept_tRNA_hydro_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001328">
        <property type="entry name" value="Pept_tRNA_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018171">
        <property type="entry name" value="Pept_tRNA_hydro_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036416">
        <property type="entry name" value="Pept_tRNA_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17224">
        <property type="entry name" value="PTHR17224"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01195">
        <property type="entry name" value="Pept_tRNA_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53178">
        <property type="entry name" value="SSF53178"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00447">
        <property type="entry name" value="pth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01195">
        <property type="entry name" value="PEPT_TRNA_HYDROL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01196">
        <property type="entry name" value="PEPT_TRNA_HYDROL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="196" mass="21435" checksum="4D716D56A01AF968" modified="2010-01-19" version="1">MSNNIRLLVGLANPGQEYAKTRHNAGAWVVEELARVHNVTLREDAKYFGLTGRITTNGQDLRLLIPTTFMNLSGKSVAALAKFFQIQPEEILVAHDELDLPPGVAKFKKGGGHGGHNGLRDIISKMGNNKDFYRLRIGIGHPGDKNKVAGFVLGKAPAKEQELIDAAVDEAVRCMDILLKDGLSKAQNRLHSFKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWQ6</accession>
    <name>D0YWQ6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Methionine transporter MetT</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_001452</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298083.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40426">
        <property type="protein sequence ID" value="EEZ40426"/>
        <property type="gene ID" value="VDA_001452"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1757">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="580055at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018461">
        <property type="entry name" value="Na/H_Antiport_NhaC-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03553">
        <property type="entry name" value="Na_H_antiporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="16"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="124"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="209"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="247"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="391"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="423"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="domain" description="Na_H_antiporter" evidence="7">
        <location>
            <begin position="30"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ40426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="452" mass="47163" checksum="BB98E219C829570F" modified="2010-01-19" version="1">MSNTTQQNETSPAPSLLALLPLGIFLALFIGVGSYLTMQGVDFAFYQLPAPVAALPAVIVAILLSKEKLNKAIEQFIRGVGHGDIIAMCMIYLLAGAFAAVAKATGGVDATVNFGLSMLPAELILPGIFIISAFIATAMGTSMGTIAAVAPVALGIAQAADMDVALTAGVVLSGAMFGDNLSIISDTTIAATRSQGCQMKDKFRENIKIALPAAIVALVVFAASSNSSEVPATEAIEWLKVLPYVTILVLAVAGVNVFVVLSLGILLAGGVGLFSEPSYHLGNFAKDIYAGFGNMQEIFLLSMLIGGMGEMMRRQGGLAYLTQLISRIIRVFSKKHSANENLRASEFGIAGLVSLTNCCTANNTVAIIVSGSVARELADENGVTPRRAASLLDIFSCVIQGLLPYGAQALLLGSVFKLSPLEVVAHSYYCIFLAVAAVVAILLKHSSRINKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWU8</accession>
    <name>D0YWU8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Amidophosphoribosyltransferase</fullName>
            <shortName evidence="5">ATase</shortName>
            <ecNumber evidence="5">2.4.2.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Glutamine phosphoribosylpyrophosphate amidotransferase</fullName>
            <shortName evidence="5">GPATase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">purF</name>
        <name evidence="10" type="ORF">VDA_001540</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>5-phospho-beta-D-ribosylamine + diphosphate + L-glutamate = 5-phospho-alpha-D-ribose 1-diphosphate + H2O + L-glutamine</text>
            <dbReference type="Rhea" id="RHEA:14905"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58681"/>
            <dbReference type="EC" id="2.4.2.14"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5 8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="5 8">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 5 6">Purine metabolism; IMP biosynthesis via de novo pathway; N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5 6">In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.14" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298240.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001540"/>
    <dbReference type="EnsemblBacteria" id="EEZ40514">
        <property type="protein sequence ID" value="EEZ40514"/>
        <property type="gene ID" value="VDA_001540"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0034">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="267682at2"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00124"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004044">
        <property type="term" value="F:amidophosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009113">
        <property type="term" value="P:purine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00715">
        <property type="entry name" value="GPATase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01931">
        <property type="entry name" value="PurF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005854">
        <property type="entry name" value="PurF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035584">
        <property type="entry name" value="PurF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000485">
        <property type="entry name" value="Amd_phspho_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01134">
        <property type="entry name" value="purF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="5 6 10" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 5 6" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="9">
        <location>
            <begin position="2"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5 7">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 8">
        <location>
            <position position="304"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 8">
        <location>
            <position position="366"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 8">
        <location>
            <position position="367"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR000485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000485-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000485-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ40514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="505" mass="55928" checksum="E03199D4E6C8AC9F" modified="2010-01-19" version="1">MCGIVGIVGETPVNQSIYDALTVLQHRGQDAAGIVTLESNRFRLRKANGLVRDVFQVKHMQRLQGMVGIGHVRYPTAGSSNASEAQPFYVNSPYGISLAHNGNLTNADAITASLFEQAKRHVNTNSDSEILLNVLAYELENATSYPLTPNDIFTAVSNVHRTVKGAYAVVAMVIGHGLIAFRDPNGIRPLCIGQREINGITEYMVASESVALDAVGFTFMRDVAPGEAIYITFDKRELFTQQCAENPALNPCVFEFVYFARPDSFIDKVSVYAARVLMGTKLGEKIKREWDDIDIDVVIPIPETSCDSALEIARTLDKPYRQGFVKNRYVGRTFIMPGQQMRRKSVRRKLNAINSEFKDKSVLLVDDSIVRGTTSEQIIEMAREAGARKVYLASAAPEVRFPNVYGIDMPSAHELIAHGRDVDEICKMIGADGLIFQDLSDLVDAVAQGNPDIKLFETSVFDGNYVTGDVDLAYLEHLEALRSETAKRKQEKMQDLANLELYNEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWY5</accession>
    <name>D0YWY5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulators LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001818</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298765.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001818"/>
    <dbReference type="EnsemblBacteria" id="EEZ40786">
        <property type="protein sequence ID" value="EEZ40786"/>
        <property type="gene ID" value="VDA_001818"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1591366at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="9"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="307" mass="35188" checksum="080CB547133A2B4F" modified="2010-01-19" version="1">MTKDLFFTLDLNLLRTFLVLSQELNTRKAAERLFVTQPAISHALQRLRNHFNDELFVKSLNGLQATPFAEELIAQLTPHLDGLSITLNASQEFHPELIERTIKIALAPQVLCAIAGRLFTKVREQAPNIDLQIVNWSMNSIDDIAKGELHFGVNYSFSNVTKEVQSRELRTVHGVIAVRDKHPIKKDTVKPQDLVDYEIASLIIPGWNTHRSHAADVMDSLGFHTKIGFRSEIPSALVDVVLQTDMYFPTSHIFPISRYKGLRTIEVDLPEEQKLQMLYSYYHKKNRNSALTQWLHRIILELLQDLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX02</accession>
    <name>D0YX02_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phage tail protein I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002055</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299297.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002055"/>
    <dbReference type="EnsemblBacteria" id="EEZ41023">
        <property type="protein sequence ID" value="EEZ41023"/>
        <property type="gene ID" value="VDA_002055"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502ZEAY">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1446675at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006521">
        <property type="entry name" value="Tail_protein_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09684">
        <property type="entry name" value="Tail_P2_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01634">
        <property type="entry name" value="tail_P2_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="249" mass="27689" checksum="F67C535668253CDA" modified="2010-01-19" version="1">MSEEIDHFISVQPENRTLIEESLEYAWHQVIAKQKDPFPELKQPLLTPNDFVSLLAGERGVTDWRPEDTIEQQRKTADKAFEIHRKAGTRHGLAVAMDALDCDIEVTPWYQMRSPPGPYHLEIVAWKRNSPVDKKTTERMLQRVENTKSERDSVDLIFAFGLDSGFSVSGVQERAIMETDSSVTGLMPTSPVCALDTQVAGAVEHVIENEMSVCGVLPNDALCQGGIYFGGGTKMLMCTDITLGAMKTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX96</accession>
    <name>D0YX96_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hypothetical nucleoside-diphosphate-sugar epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001955</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299010.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001955"/>
    <dbReference type="EnsemblBacteria" id="EEZ40923">
        <property type="protein sequence ID" value="EEZ40923"/>
        <property type="gene ID" value="VDA_001955"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0702">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1928091at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021295">
        <property type="entry name" value="DUF2867"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11066">
        <property type="entry name" value="DUF2867"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="441"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="2">
        <location>
            <begin position="9"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="487" mass="55124" checksum="374CF35BEA2B1187" modified="2010-01-19" version="1">MVRTILVVGASGYIGSNLVPKLAQRGYSVKATGRNLSLLKKKGWNKLDNVSLHYLDLDEKSDLTKLLSDVDLVFFLVHGMTHGHDFIDYEIEAAQHFSDGLKQSQVKHVIYLGALQSNNSDSKHLIARKATGEILRQSEKPVTELRAGIIIGPGSAAFEVMCDFVYHLPIMLTPKWVTSRNSPIALCNLLHYLFELINMPPSSHRIWDVSGPEQMSYKDQMIRLGKIIHKPIRVLPIPFLSPTLAAYWLRFITSVPTNIAKALIGGLRFDLPADGTQIQQAIPQTLLTYEEAVSIALKKQVEVVANPIWGFNPDAIERWQTGYGYYPKQAGYTLKTDASLDALWQQIQRLGNPGTEYFFANSLWHLREWMDKIIGGNACERYRRDPDTLQLGDRIDSWKVIALEDKHFISLLFGMKAPGLGRLEFTIKDHGNYRTLDIRAWWHPAGFSGLLYWFAMMPAHLFIFRGMTHAVAKKSKAHIKKGKIDTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXA2</accession>
    <name>D0YXA2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 11">Adenylosuccinate lyase</fullName>
            <shortName evidence="11">ASL</shortName>
            <ecNumber evidence="4 11">4.3.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 11">Adenylosuccinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">VDA_001642</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + fumarate</text>
            <dbReference type="Rhea" id="RHEA:23920"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:58443"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="EC" id="4.3.2.2"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:23921"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>N(6)-(1,2-dicarboxyethyl)-AMP = AMP + fumarate</text>
            <dbReference type="Rhea" id="RHEA:16853"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:57567"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="4.3.2.2"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:16854"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Purine metabolism; AMP biosynthesis via de novo pathway; AMP from IMP: step 2/2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 11">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.2" evidence="4 11"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298428.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001642"/>
    <dbReference type="EnsemblBacteria" id="EEZ40615">
        <property type="protein sequence ID" value="EEZ40615"/>
        <property type="gene ID" value="VDA_001642"/>
    </dbReference>
    <dbReference type="GeneID" id="57342276"/>
    <dbReference type="eggNOG" id="COG0015">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="347727at2"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00132"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00075">
        <property type="reaction ID" value="UER00336"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070626">
        <property type="term" value="F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004018">
        <property type="term" value="F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044208">
        <property type="term" value="P:'de novo' AMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004769">
        <property type="entry name" value="Pur_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013539">
        <property type="entry name" value="PurB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08328">
        <property type="entry name" value="ASL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="SSF48557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00928">
        <property type="entry name" value="purB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 11" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lyase_1" evidence="12">
        <location>
            <begin position="14"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="ASL_C" evidence="13">
        <location>
            <begin position="331"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEZ40615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="455" mass="51287" checksum="D8847F688D3B53F9" modified="2010-01-19" version="1">MELSALTAVSPVDGRYGSKTSVLRSIFSEFGLLKYRTIVEIRWLQKLAATDAIVEVPAFSAEANAYLDRIAAEFSEEDALRIKEIERTTNHDVKAVEYFLKEKVAQVPELHAVNEFIHFACTSEDINNLSHALMLTEAREKVMLPEVRNVIDAIKDLANQFRHVPMLTRTHGQPASPSTMGKEMANVAYRMERQFKQIANVEILGKINGAIGNYNAHLSAYPEIDWHQYSEEFVTSLGVTWNPYTTQIEPHDYIAELFDAFARFNTILLDFDRDVWGYIALGHFKQKTVAGEIGSSTMPHKVNPIDFENSEGNLGLANAIFAHLAQKLPVSRWQRDLTDSTVLRNLGVGCGYAIIAYTSTLKGISKLEVNQAALEAELDRNWEVLAEPIQTVMRRYGIEKPYEKLKELTRGKRVDSEGMRTFIDGLELPEEEKVRLKAMTPATYIGAAVELTDKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXE1</accession>
    <name>D0YXE1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Ion-translocating oxidoreductase complex subunit A</fullName>
            <ecNumber evidence="10">7.-.-.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Rnf electron transport complex subunit A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">rnfA</name>
        <name evidence="11" type="ORF">VDA_001620</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Cell inner membrane</location>
            <topology evidence="2 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the NqrDE/RnfAE family.</text>
    </comment>
    <dbReference type="EC" id="7.-.-.-" evidence="10"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298387.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001620"/>
    <dbReference type="EnsemblBacteria" id="EEZ40593">
        <property type="protein sequence ID" value="EEZ40593"/>
        <property type="gene ID" value="VDA_001620"/>
    </dbReference>
    <dbReference type="GeneID" id="57342302"/>
    <dbReference type="eggNOG" id="COG4657">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1814639at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022900">
        <property type="term" value="P:electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00459">
        <property type="entry name" value="RsxA_RnfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011293">
        <property type="entry name" value="Ion_transpt_RnfA/RsxA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003667">
        <property type="entry name" value="NqrDE/RnfAE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02508">
        <property type="entry name" value="Rnf-Nqr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006102">
        <property type="entry name" value="NQR_DE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01943">
        <property type="entry name" value="rnfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="99"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="134"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ40593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="193" mass="20861" checksum="E3F448AB0D704A3C" modified="2010-01-19" version="1">MTEYLLLLVGTVLVNNFVLVKFLGLCPFMGVSKKLETAIGMGLATTFVLTLASVCAYLVETYLLEPLGLEYLRTLSFILVIAVVVQFTEMVVHKTSPTLYRLLGIFLPLITTNCAVLGVALLNVNEHHNFIESVIYGFGAAVGFSLVLVLFASMRERIAAADVPMPFKGASIAMITAGLMSLAFMGFTGLVKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXP4</accession>
    <name>D0YXP4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Sensory box/GGDEF family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_001747</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298617.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001747"/>
    <dbReference type="EnsemblBacteria" id="EEZ40715">
        <property type="protein sequence ID" value="EEZ40715"/>
        <property type="gene ID" value="VDA_001747"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5001">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033417">
        <property type="entry name" value="CHASE8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17152">
        <property type="entry name" value="CHASE8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="3">
        <location>
            <begin position="188"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="2">
        <location>
            <begin position="254"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="2">
        <location>
            <begin position="372"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="4">
        <location>
            <begin position="527"/>
            <end position="661"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ40715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="676" mass="76267" checksum="FCDB1BF8F19994B6" modified="2010-01-19" version="1">MKLLWPSSLSLSQRLFLPMLSFVVILFIVFQTISYYKYVGNAEKNLLNRVTILATGIGTNLTAAIQFDDELAGAEILSAFKADPSITSVEVVLPNKPYPFASFQQTNSTVSEKLSDNDWQQIQTYTVNHHSLYLVLPIQLEQQTIAHMRLTVSLSDMVAMQYYQIKISGWMLLSLIVVSSLLLLRLQRWVTQPISSLHSAMLNIINNDQNQQVEITSLHQDEVGKLVSCFNTMIDKLNQREEQIHNSLTQLNNEKAFANNVIASVQHALIVTDLNGIIILANNSCSKVFGLTPNQLLQRPIISIIKPLEPLVFNNALHAALKGQQHFKGEAIRSAGNTALSMYHIVSHPLPHKQQILFSIEDITEKSQAEANQRMAAQIFENSQDAILLLDGSGHIILVNPALCRLFGVDEHQILKRHYHCLLTNSDYHQLKRSIREALLFTQQWQGEGCIYNQKTKTKIPLFLKINKIIDKDSQETHISVVASDLSSAKEVQRLAQIAHHDALTHLPNRHHLHQHLSQLLTAPREHNVAVLFIDLDGFKNVNDIYGHNIGDKALKIVAKKLLLSTRQNDLVARLAGDEFIVVLNQVTNKTLIEQICNRILNALSTPMNIHSYHVEIGASIGFYTIPPNETTNIDDILSFADIAMYQSKIAGKGRFTEYRKDLFTQVTSKYETEHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXU7</accession>
    <name>D0YXU7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RES domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002110</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MbcT/ParT/Res family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299464.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002110"/>
    <dbReference type="EnsemblBacteria" id="EEZ41078">
        <property type="protein sequence ID" value="EEZ41078"/>
        <property type="gene ID" value="VDA_002110"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5654">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1154993at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014914">
        <property type="entry name" value="RES_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08808">
        <property type="entry name" value="RES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00953">
        <property type="entry name" value="RES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RES" evidence="2">
        <location>
            <begin position="75"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="224" mass="25239" checksum="B51371B938BB64C2" modified="2010-01-19" version="1">MGVKIEYKGHRLINTKYPPIALFDDVASPEEFELLYAIQALTNPRLRDEVGDICLIDPAEIPFDCLRGRSYAVAPFTHINPKGGRFNDGLFGALYVADNAHTAALEVKFHQQEYWQNIEGLEYDRFLFRGLLISHQSAPIYHVCGDDSAILNPDCYSAAQQLARKVKKEGFQAIEYPSVRAEDALCWAIFTPKPITDVVQSYLVEMIWNGEQIAEVNTVENLGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXZ4</accession>
    <name>D0YXZ4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002157</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299559.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002157"/>
    <dbReference type="EnsemblBacteria" id="EEZ41125">
        <property type="protein sequence ID" value="EEZ41125"/>
        <property type="gene ID" value="VDA_002157"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3516">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1278805at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008312">
        <property type="entry name" value="T6SS_TssB1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35850">
        <property type="entry name" value="PTHR35850"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05591">
        <property type="entry name" value="T6SS_VipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028301">
        <property type="entry name" value="UCP028301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03358">
        <property type="entry name" value="VI_chp_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="165" mass="18165" checksum="47830BB0ACCA5965" modified="2010-01-19" version="1">MSKDGSVAPKERINIKYVPHNGDDQSSVELPLKALIVSDFKGGVEDVAIEDRKAVSIDKNNFESVMKESNLSITTTVNNKLSDDGSELPITLSIQSLDDFSPDSIGQQVPELKKLIELREALVALKGPLGNIPAFRTRLQELMDSEESRSKLLSELEIVSQDLNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY12</accession>
    <name>D0YY12_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002175</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299592.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41143">
        <property type="protein sequence ID" value="EEZ41143"/>
        <property type="gene ID" value="VDA_002175"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4815">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011235">
        <property type="entry name" value="MepB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038231">
        <property type="entry name" value="MepB-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08877">
        <property type="entry name" value="MepB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="181" mass="20851" checksum="C2F3351C00914575" modified="2010-01-19" version="1">MHSEYNWFENPKFGETPVSFLELIDKVLIPLSPDGITNVEREQESGEYGAVKFTFNGLKCLFRQGKTTPTKVGQFVTLWKRETNKSEIIPFNTYDGIELVFIASFESDNKGFFVFQNELLTNKNIFSHNGREGKRAIRVYAPWIKLTAKQAISTQQWQISEFINLNLDFEVIQSKAKQLIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY40</accession>
    <name>D0YY40_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_002203</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299642.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002203"/>
    <dbReference type="EnsemblBacteria" id="EEZ41171">
        <property type="protein sequence ID" value="EEZ41171"/>
        <property type="gene ID" value="VDA_002203"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0733">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="376209at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000175">
        <property type="entry name" value="Na/ntran_symport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037272">
        <property type="entry name" value="SNS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616">
        <property type="entry name" value="PTHR11616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00209">
        <property type="entry name" value="SNF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00176">
        <property type="entry name" value="NANEUSMPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161070">
        <property type="entry name" value="SSF161070"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00610">
        <property type="entry name" value="NA_NEUROTRAN_SYMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50267">
        <property type="entry name" value="NA_NEUROTRAN_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0769">Symport</keyword>
    <keyword evidence="3 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="84"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="180"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="221"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="257"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="320"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="357"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="385"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="426"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="460"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="493" mass="53704" checksum="F55445FC278BCCB1" modified="2010-01-19" version="1">MGREQWGSRAGFILAAVGSAIGLGNIWRFPYMAYENGGGAFFIPYLFAMLTAGIPFMIMEFTLGHKLRSAAPRAFAKLGGKYEWLGWFQVFIAAVIAVYYVAVIGWAISYLGFSFKQSWGSDTNAFFFSEYLKLGEHSPSQLGGFQLHIAIPMMIAWAITFAAIYSGVKGGIERASKIMMPLLFIMVLGLITRVVFLPGALDGLNYLFQPDFSKILDAKVWSAAYGQIFFTLSVGFAIMIAYSSYLPSKSDINNNAFMTVLINCGFSITAGVLIFAVLGYMAQEQAKPLTEVVSAGVGLAFVTIPAAINLLPAPYILGPLFFLALVVAGLSSHISIIEAVTSAVIDKLNWSRKKAAIVVCGTGFIVSMAFATNGGLLLLDLVDYFINNVALLSSCLLELLIVGWLVKIADIRQYANSISDFTISKWFELCIRFISPIMLAIILVTNLYKTLAEGYGGYDMFDLLTLGWGLVGMMIVVSIIINLASKSPNQQEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY56</accession>
    <name>D0YY56_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pyridoxamine 5'-phosphate oxidase-related putative heme iron utilization protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002219</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299673.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002219"/>
    <dbReference type="EnsemblBacteria" id="EEZ41187">
        <property type="protein sequence ID" value="EEZ41187"/>
        <property type="gene ID" value="VDA_002219"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0748">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1822051at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014419">
        <property type="entry name" value="HutZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011576">
        <property type="entry name" value="Pyridox_Oxase_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01243">
        <property type="entry name" value="Putative_PNPOx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004633">
        <property type="entry name" value="UCP_PLP_oxd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04110">
        <property type="entry name" value="heme_HutZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Putative_PNPOx" evidence="1">
        <location>
            <begin position="13"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="185" mass="21052" checksum="F72A15C847C267D9" modified="2010-01-19" version="1">MNQVKQERLQSRLEPEIKEFRDSCLTLQLATVDNSGQPNVSYAPFVLLEDGYYVLISQIAKHARNLLENPRVSLMMIEDEKTAKVLYARKRLTFEADVEKVERESAAWLLAIDGLTNRFGEIVEGLSGLEDFVLFRLKPTHGLFVKGFGKAFQVSGDDLIDFVHLTEGHRRIKDGSEIQEPSEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY61</accession>
    <name>D0YY61_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Hemin ABC transporter permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_002224</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299685.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002224"/>
    <dbReference type="EnsemblBacteria" id="EEZ41192">
        <property type="protein sequence ID" value="EEZ41192"/>
        <property type="gene ID" value="VDA_002224"/>
    </dbReference>
    <dbReference type="GeneID" id="57341623"/>
    <dbReference type="eggNOG" id="COG0609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1283908at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037294">
        <property type="entry name" value="ABC_BtuC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000522">
        <property type="entry name" value="ABC_transptr_permease_BtuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30472">
        <property type="entry name" value="PTHR30472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01032">
        <property type="entry name" value="FecCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81345">
        <property type="entry name" value="SSF81345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="95"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="124"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="158"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="201"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="251"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="291"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="319"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ41192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="345" mass="36146" checksum="772C8C396BF12B57" modified="2010-01-19" version="1">MGNQRLSIRSLYPIGFGLLLLAIVSSIVIGPMSISYSDSIKALLPWHTELPNHISLVINQIRLPRTLLCIMIGAILAICGAVMQGLFRNPLADPAIIGVTGGAGLGAALAIIVFAPIAAQFPTILNLGAIPLFAFIGGVISTFFVYRLGTGTNGTSVTVMLLAGVAISAISGAGLGLLNYVADDQALRDFSLWSMGSLAGATWSGIALATVSFVALFFFFYRKANALNAFLLGESEAKHMGVNVQRLKKQLIITCAAGVGVTVSLTGPIGFIGLIIPHLGRMLIGPNHKNLIPVSALLGAFILLLADMIARTAFAPQELPVGIITAIIGAPFFIMLLIQQKGRMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYB5</accession>
    <name>D0YYB5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002278</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299776.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002278"/>
    <dbReference type="EnsemblBacteria" id="EEZ41246">
        <property type="protein sequence ID" value="EEZ41246"/>
        <property type="gene ID" value="VDA_002278"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1289">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="319122at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="149"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="369"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="393"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="439"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="462"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="646" mass="75043" checksum="3DB6F8FEFE4777A5" modified="2010-01-19" version="1">MRKPAFTAVFARWFSDAADIPDSIRITVPMVASLYLFYSFNLTAAGISGLITGWLVGVQGRDLPYLKRFQILSLSTVFTGVATVLAYAVFANTLLSAITLCSIAVVYGLMSNQRPHIRLFSYNFGFTYIMAIHFASTGVPQWATLGANIFAGCGVIFTSLMLWPFFRGRILQKHIDGVHIALVDWLNSLHYDLDINTLATRRQDFYDKAHKLAYFSNSITSAKKEQKVKSDLQRKLDVSEYIISLERLMHSNIDNHTKSLLTEWIREAANQLSQGLMISAKFPQLKIENSHYIYDLTERIKYCYNHQDETIEALSDNIYLFKGDFRAFLHDFSLAIKPHSKEWKHGFKIAMTLAVTQFLTYFYKIPQGYWISLTAFIVMLTSSMGVTNNRMWYRFYGTALGGVYSFVCLYFFKDQYLMLLTSISVFFAFTTYHKERYDIHVFWLTSMIVFAVRLLMPEDIYLSAYRVIDTLFGVTIAFSVNYFIAPNWTMKSIDKYVSAMFKSQIFYIAGLNKPQWEQKVSLYQTQNHYYAMKTEIMNLLKEPNLSPRTSKDWMSLLALLRRLNGSLLLASKVGVRSMKHHDLSQRWIHQVQWLEQTFPHRCSQGDLPPYHNEPQQPHNDLICELIEHDIKQLEQWMLYQRAYVIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-02-10" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYC4</accession>
    <name>D0YYC4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase OrfAB subunit B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002287</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41255">
        <property type="protein sequence ID" value="EEZ41255"/>
        <property type="gene ID" value="VDA_002287"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2801">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032196">
        <property type="term" value="P:transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038965">
        <property type="entry name" value="InsF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46889:SF1">
        <property type="entry name" value="PTHR46889:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="1">
        <location>
            <begin position="52"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="203" mass="23869" checksum="8D4DCBEFAF52D763" modified="2010-01-19" version="1">MVTTQGIPLSRYRASKQMKALNLVSCQSPKHRYRKANQEHIAIPNHLDRQFAVTSPNQVWVGDVTYVWAGNRWMYLAVVIDLFSRKPVGWAMSLSPDSRLTGKALMMAYESRHKPKGVMFHSDQGSHYTSSYYRQLLWRCQIKQSLSRRGNCWDNAPMERFFRSLKTEWVPNVGYRSFAEAKHEITRYIIGYYSQLRPHQYKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYD0</accession>
    <name>D0YYD0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Probable MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_002293</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299805.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002293"/>
    <dbReference type="EnsemblBacteria" id="EEZ41261">
        <property type="protein sequence ID" value="EEZ41261"/>
        <property type="gene ID" value="VDA_002293"/>
    </dbReference>
    <dbReference type="GeneID" id="57341523"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1594866at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="9"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="100"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="135"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="166"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="216"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="254"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="284"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="308"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="340"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="372"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="8"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="404" mass="44043" checksum="E32A8A369694CEAA" modified="2010-01-19" version="1">MSIFRFPLLVWMGIGILIISLGIRQSFGIFMMPISDTFHTGREFFSLAIALQNLLFGLFQPFVGMAADRFGARRIIIVGAIAYGAGLYLTSLAATPSVLYLTIGALIGLGLSATSYVIILGAVARVVPAEHTAKAFGLTTAAGSFGMFAVIPGAQALLRNFDWQTAMQIFAVICCVMIAFAGFIKSQKATSDTPSQVDDSQTLSEALQEAFRNRNYWLIHAGFFVCGFQVMFIATHLPSYLGDKGLPGNTAAMALAYVGVFNIFGSYFWGLMGDRFDKRYVMSSLYLMRTVIIAAFVTFPVTVNTASIFGAAIGFCWLGTVPLTSGLVRQIFGARYLSTLYGLVFFTHQVGSFLGAWVGGRIFDYYHSYTPIWWTTVVMALIAALLHLPINDKPVPRLIAQHAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYD9</accession>
    <name>D0YYD9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted L-lactate dehydrogenase Fe-S oxidoreductase subunit YkgE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002302</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002302"/>
    <dbReference type="EnsemblBacteria" id="EEZ41270">
        <property type="protein sequence ID" value="EEZ41270"/>
        <property type="gene ID" value="VDA_002302"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0247">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004017">
        <property type="entry name" value="Cys_rich_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02754">
        <property type="entry name" value="CCG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CCG" evidence="1">
        <location>
            <begin position="75"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="181" mass="19975" checksum="7826C9F883A8641E" modified="2010-01-19" version="1">MKNLIAAFECNDYPIVTPAGSCAASIKKYPEYLADEPEWAARAQKVSDRLFELTQFIVNQLGIENVGARLPGKAVYHPSCSLIRKLGVREEPLKLLANVEGLEMLPIENQETCCGFGGTFSVKMAEISGEMVKEKVRHIKAAEPDYLIGADISCLLNIGGRIQREGQPIKVMHIVDVLMSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYF5</accession>
    <name>D0YYF5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RNA polymerase sigma factor RpoS</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_002318</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299852.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002318"/>
    <dbReference type="EnsemblBacteria" id="EEZ41286">
        <property type="protein sequence ID" value="EEZ41286"/>
        <property type="gene ID" value="VDA_002318"/>
    </dbReference>
    <dbReference type="GeneID" id="57341497"/>
    <dbReference type="eggNOG" id="COG0568">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000943">
        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009042">
        <property type="entry name" value="RNA_pol_sigma70_r1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00140">
        <property type="entry name" value="Sigma70_r1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000770">
        <property type="entry name" value="RNA_pol_sigma-SigE/K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00046">
        <property type="entry name" value="SIGMA70FCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r1_2" evidence="5">
        <location>
            <begin position="8"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r2" evidence="6">
        <location>
            <begin position="43"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4" evidence="7">
        <location>
            <begin position="208"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ41286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="282" mass="32432" checksum="9A8FA98F9325E685" modified="2010-01-19" version="1">MDIQSVTGIYLKQLRSRALLTKEEEIELSIKVQAGDQKARAKLIESNLRLVVSIAKKMQHRGLDLDDLINEGNIGLITAVEKFNPDYGYRFSTYATWWIKQAMDRAIHNHSREVRLPVHISKELCTIYSAFKEMSTKSEQVTIDQVSALTGSPKEEIEKILKYERRYSSLDDQFDEGAKFSEIIPDHSKLDHTELLNEEDQTEVLAMLLAELKPRDQEIIARRFGLFGYEPHTLQEVATAVNLTRERVRQLQILAQQRLAAKMRDRNITLESMLVEEAVAFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYI0</accession>
    <name>D0YYI0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002343</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002343"/>
    <dbReference type="EnsemblBacteria" id="EEZ41311">
        <property type="protein sequence ID" value="EEZ41311"/>
        <property type="gene ID" value="VDA_002343"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1215">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="235"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="267"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="9"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="322" mass="36706" checksum="BAC8FFFF2056DADA" modified="2010-01-19" version="1">MIKEDYRLSLIVPVYNEEESIETFIGAINTRLASIRSHIDIVFINDGSSDNTRTVIENQIRQDDSITLINLAKNFGKEAAMTAGLNYVEGDAAVILDVDLQDPPELILEFVRLWQTGEYDTVYGVRVDRSHDTFMKRFTAGGFYRFFNLLSSGTRLPENVGDFRLIDRSVIEAIKQLPERNRFMKGLLAWSSFRSIGVDFQRPERCAGDTKFNYWKLWNFAVDGIFSFTAWPLRVWGFIGLGISFLSFIFLMYVLISALFFGIHTPGYASTISVVLFLGGIQLISLGVIGGYISRIYVEVKQRPIYLIEGVYGKYKEQKPNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYK0</accession>
    <name>D0YYK0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Trimethylamine-N-oxide reductase</fullName>
            <shortName evidence="4">TMAO reductase</shortName>
            <ecNumber evidence="4">1.7.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">torA</name>
        <name evidence="8" type="ORF">VDA_002363</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Reduces trimethylamine-N-oxide (TMAO) into trimethylamine; an anaerobic reaction coupled to energy-yielding reactions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>2 Fe(III)-[cytochrome c] + H2O + trimethylamine = 2 Fe(II)-[cytochrome c] + 3 H(+) + trimethylamine N-oxide</text>
            <dbReference type="Rhea" id="RHEA:24236"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15724"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:58389"/>
            <dbReference type="EC" id="1.7.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
            <dbReference type="ChEBI" id="CHEBI:60539"/>
        </cofactor>
        <text evidence="4">Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="4">Exported by the Tat system.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.7.2.3" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002363"/>
    <dbReference type="EnsemblBacteria" id="EEZ41331">
        <property type="protein sequence ID" value="EEZ41331"/>
        <property type="gene ID" value="VDA_002363"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0243">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030151">
        <property type="term" value="F:molybdenum ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043546">
        <property type="term" value="F:molybdopterin cofactor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050626">
        <property type="term" value="F:trimethylamine-N-oxide reductase (cytochrome c) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02793">
        <property type="entry name" value="MopB_CT_DMSOR-BSOR-TMAOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041954">
        <property type="entry name" value="CT_DMSOR/BSOR/TMAOR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041460">
        <property type="entry name" value="Molybdopterin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006657">
        <property type="entry name" value="MoPterin_dinucl-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006656">
        <property type="entry name" value="Mopterin_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006655">
        <property type="entry name" value="Mopterin_OxRdtase_prok_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011887">
        <property type="entry name" value="TorA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00384">
        <property type="entry name" value="Molybdopterin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18364">
        <property type="entry name" value="Molybdopterin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01568">
        <property type="entry name" value="Molydop_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="SSF50692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02164">
        <property type="entry name" value="torA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00490">
        <property type="entry name" value="MOLYBDOPTERIN_PROK_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 4" id="KW-0574">Periplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Molybdopterin_N" evidence="7">
        <location>
            <begin position="30"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="Molybdopterin" evidence="5">
        <location>
            <begin position="74"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="domain" description="Molydop_binding" evidence="6">
        <location>
            <begin position="663"/>
            <end position="783"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU368014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF18364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ41331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="807" mass="91292" checksum="7C0013EDC4FBE6C4" modified="2010-01-19" version="1">MTSAAGVIGPSLLASSKAFAVETTGTWKYSGSHWGAFRAHIYGGRVQEIEAIEIDTNPTEMLKGIKGVIYNPSRVRYPMVRLDWLKKNKYSGETRGNNRFVRVTWDEALDLFYQELERMQKDYGPWAIHAGQTGWRQTGQFHSCTSHMQRAVGMHGNYITKVGDYSTGAGQTIMPYVLGSTEVYAQGTSWSEILDNTKTLILWANDPVKNLQVGWNCETHESYPYLAQLKEKVAQGEIKVISVDPVKNKTQQYLDNEHLYINPQTDVAFMLGVAHTLYNENLYDKDFIKMYCLGFDEFIGYVKGETKDKVEKTPEWASAICGVPADQIREFARLLVKDRTQIMFGWCIQRQEHGEQPYWMGAVVAAMVGQIGLPGGGISYGHHYSGIGVPSTGFAAPGGFPRNVDEGHKPKWDNNDFNGYSRTIPVARFVDCILEPGKEIQYNGSKVILPGYKMMVISGNNPWHHHQDRNRMKQAFQKLQTVVTIDYAWTATCRFSDIVLPACTQFERNDIDVMGSYSGRGLLAMHKLVDPLYQSKTDFEIFTELTRRFGRHKEYTRGMDEMEWVSMLYNDCRAANKGKFDMPEFDVFWQQGFLDFGTGQPWVRHADFRKDPEINALGTPSGFIEISSRKIGRYNYEHCQNHPMWFEKTERSHGGPGSDKHPFWLQSCHPDKRLHSQMCESDEFRATYTVQDREPIYMNPKDAAKKGIKAGDVVRVFNDRGQLLAGAVLSDSYAEGVVRIEEGAWYGPLNEKIGAIDTYGDPNTLTMDIPSSELAQATSAQTCLVDFEKFQGELPPVTSFGGPIEVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYK7</accession>
    <name>D0YYK7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DNA gyrase subunit A</fullName>
            <ecNumber evidence="8">5.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">gyrA</name>
        <name evidence="12" type="ORF">VDA_002370</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="8">Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the topoisomerase GyrA/ParC subunit family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the type II topoisomerase GyrA/ParC subunit family.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299973.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002370"/>
    <dbReference type="EnsemblBacteria" id="EEZ41338">
        <property type="protein sequence ID" value="EEZ41338"/>
        <property type="gene ID" value="VDA_002370"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0188">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="217468at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034335">
        <property type="term" value="F:DNA negative supercoiling activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00187">
        <property type="entry name" value="TOP4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.268.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.199.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01897">
        <property type="entry name" value="GyrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005743">
        <property type="entry name" value="GyrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006691">
        <property type="entry name" value="GyrA/parC_rep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035516">
        <property type="entry name" value="Gyrase/topoIV_suA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013760">
        <property type="entry name" value="Topo_IIA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013758">
        <property type="entry name" value="Topo_IIA_A/C_ab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013757">
        <property type="entry name" value="Topo_IIA_A_a_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002205">
        <property type="entry name" value="Topo_IIA_dom_A"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03989">
        <property type="entry name" value="DNA_gyraseA_C"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00521">
        <property type="entry name" value="DNA_topoisoIV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00434">
        <property type="entry name" value="TOP4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101904">
        <property type="entry name" value="SSF101904"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56719">
        <property type="entry name" value="SSF56719"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 8 12" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="TOP4c" evidence="11">
        <location>
            <begin position="11"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="835"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="477"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GyrA-box" evidence="8">
        <location>
            <begin position="559"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="841"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-tyrosine intermediate" evidence="8">
        <location>
            <position position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ41338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="873" mass="97150" checksum="62605562D3D79109" modified="2010-01-19" version="1">MSDLAKEITPVNIEEELKGSYLDYAMSVIVGRALPDVRDGLKPVHRRVLFAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEVRMSKIAHELLADLEKDTVDYVPNYDGTEHIPAVLPTKIPNLLVNGSSGIAVGMATNIPPHNLGEVIDGCLAYIDNEEITIDQLMEYIPGPDFPTAAMISGRKGIIDAYKTGRGKIYMRSKAEIEADKNGRETIIVTEIPYQVNKARLIEKIAELVKEKKVEGISALRDESDKDGMRIVIECKRDAVGEVVLNNLYAQTQLQTTFGINMVALDNGQPKLFNLKEMLKCFVNHRREVVTRRTIFELRKARDRAHILEGLALALANIDEIIELIRRAPTPAEAKAGLVARGWELGNVAAMLERAGTDAARPDWLAEEFGIRDNLYYLTEQQAQAILDLRLHKLTGLEHEKILDEYKTLLEEIAELLHILSSAERLMEVIREELELVKEQFNDARRTEITAATHDIDLEDLINQEDVVVTLSHEGYVKYQVLTDYEAQRRGGKGKAATRMKDEDFIERLLVANTHDTILCFSTRGRMYWLKVYQLPLASRTARGKPIVNILPLEENERITAILPVKEYEADKFVFMATADGTVKKTPLTDFSRPRSAGIIAVNLRDEDTLIGVDITDGNNDIMLFSKAGKVVRFNEGQVRAMGRTAAGVRGIKLAESDNVVSLIVPHNDGDVLTVTENGYGKRTELEEYPAKSRATQGVVSIKVSERNGSVVGAVQVLEGDEFMMITNGGTLVRTRVAEVSRVGRNTQGVTLIRTTEDEKVVGLQRIDEPDEDDIIEDAEITEVENTETPAADSEQGDSSEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYR1</accession>
    <name>D0YYR1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">3-ketoacyl-CoA thiolase</fullName>
            <ecNumber evidence="8">2.3.1.16</ecNumber>
            <ecNumber evidence="8">2.3.1.9</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_002424</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.16" evidence="8"/>
    <dbReference type="EC" id="2.3.1.9" evidence="8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300066.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002424"/>
    <dbReference type="EnsemblBacteria" id="EEZ41392">
        <property type="protein sequence ID" value="EEZ41392"/>
        <property type="gene ID" value="VDA_002424"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0183">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1058688at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003985">
        <property type="term" value="F:acetyl-CoA C-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020615">
        <property type="entry name" value="Thiolase_acyl_enz_int_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020610">
        <property type="entry name" value="Thiolase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020613">
        <property type="entry name" value="Thiolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00098">
        <property type="entry name" value="THIOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00737">
        <property type="entry name" value="THIOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00099">
        <property type="entry name" value="THIOLASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase_N" evidence="6">
        <location>
            <begin position="4"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase_C" evidence="7">
        <location>
            <begin position="272"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="4">
        <location>
            <position position="88"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="357"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000429-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ41392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="401" mass="41456" checksum="97C5A63F3F320B4C" modified="2010-01-19" version="1">MERVFIVAAKRSAIGAFGGTLKDQAAGKIAAEVIKGALDAANINGAQVDEVIVGNVVGAGQGMGVGRQASLWAGIPATVPAYSLNMVCGSGMKTVMDGVSHIRSGDAKVVVAAGVEIMSQIPFIVPSKVRDGQKMGNLTLTDLLIADGLTDVYNQCHMGVTAENIAKQLDISRQEQDEFALASQQKAVAAIEMGKFEDEIVPLEIQQRKGTITFSTDEYPKANASLDALASLRPAFDREGSVTAGNASGINDGASAVILASESALKAHNLIPLAEIVGYAQSGLEPEIMGLGPVEAVTKALAQAELNLSDIAVFELNEAFAAQALGVVYQLAEKHQVEASDIIAKANLNGGAIALGHPLGASGNRILVTLTHELKKQRGRYGVASLCVGGGMGTAIVIKAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYX5</accession>
    <name>D0YYX5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002488</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300188.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002488"/>
    <dbReference type="EnsemblBacteria" id="EEZ41456">
        <property type="protein sequence ID" value="EEZ41456"/>
        <property type="gene ID" value="VDA_002488"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3102">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1257033at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010393">
        <property type="entry name" value="DUF991"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37519">
        <property type="entry name" value="PTHR37519"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06185">
        <property type="entry name" value="YecM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="194" mass="22083" checksum="B8F8185417EE784E" modified="2010-01-19" version="1">MQKLKEIGLHPEQMLANLPAFMNKITSLLQELNISLTEYKADHIALRVNNYADAELLHQAWLEYGIEWSNNWINGRPIIVIGFTQPLQVGDWTIEALELPYPSNKIYPQQGWEHIEFVIPSNARTTDELKQHLAEQLPSLDWSGFEEKQVKVKASSPAGEKERLPNPTIAFKKDGVCIKLHPCSLKAVLESESE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ43</accession>
    <name>D0YZ43_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acyl-CoA thioesterase II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002556</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the C/M/P thioester hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300318.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002556"/>
    <dbReference type="EnsemblBacteria" id="EEZ41524">
        <property type="protein sequence ID" value="EEZ41524"/>
        <property type="gene ID" value="VDA_002556"/>
    </dbReference>
    <dbReference type="GeneID" id="57341203"/>
    <dbReference type="eggNOG" id="COG1946">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="990202at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047617">
        <property type="term" value="F:acyl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006637">
        <property type="term" value="P:acyl-CoA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042171">
        <property type="entry name" value="Acyl-CoA_hotdog"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003703">
        <property type="entry name" value="Acyl_CoA_thio"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11066">
        <property type="entry name" value="PTHR11066"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00189">
        <property type="entry name" value="tesB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="288" mass="32703" checksum="1BB0336FBF38D93E" modified="2010-01-19" version="1">MSQELNELLNLLHLERLEQGLFRGQSENLGLPQVYGGQVIGQSLSAAKKTVEADRHVHSFHSYFLLPGDPEKPIIYDVEKLRDGKSFSTRRVKAIQNGRPIFYLTASYQAEESGFEHQAPMPIDDVPSPEELPSERQLVQSIAQYLPPKLVEIFGRERPIEVRPAVVVNPLNPKKEPAKQYLWIKANGEMPDDQRIHQYVLAYASDWGFLVTALQPHGVTLFTPKMQVATIDHSMWFHRPFRMDEWLLYVIDSPSASGGRGLVRGEIYNQQGELVASAVQEGLMRMKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-06-02" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ68</accession>
    <name>D0YZ68_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CheW-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002581</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300388.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002581"/>
    <dbReference type="EnsemblBacteria" id="EEZ41549">
        <property type="protein sequence ID" value="EEZ41549"/>
        <property type="gene ID" value="VDA_002581"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0835">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1711729at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036061">
        <property type="entry name" value="CheW-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002545">
        <property type="entry name" value="CheW-lke_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014506">
        <property type="entry name" value="UCP020479_CheW"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01584">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF020479">
        <property type="entry name" value="UCP020479_CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00260">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50341">
        <property type="entry name" value="SSF50341"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50851">
        <property type="entry name" value="CHEW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CheW-like" evidence="2">
        <location>
            <begin position="253"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="400" mass="45070" checksum="49F5943D23B2F7A4" modified="2010-01-19" version="1">MANKPLSSEQALNDYFSDLLVEELWDEPSSEDFDSKSPDSETLDFEDPGSKVSTFEHYPLETTADISKDCEDTDICDNAQDITADSESTHLASKEKWLDTDTLIKCSRSQIHIEPKYAEPILTESVFAEPILAEPVSESQLQLQQLLDTWSQQQDEHWVSLADVHSEPAIELTIEPAIEPELEENRDALVVSIVEPEILADFSDSSAEPIAETLPVLERDDALFADVETEHQALVLEASAPINEWQGQFTSSSFQALFFEVNGVMFAVALEQLGGIHRLGELNHLLGRPKWYLGLQSSPSLQLDVVDTARWVMSDKLRNDDYLENYQYIVMLGESRWGLACDQLHGTQTLLSTDIQWREQAGKRPWLAGMVKEKMCALIHVSEMITMLNQGWDVKALTHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZB5</accession>
    <name>D0YZB5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glutamate--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Glutamyl-tRNA synthetase</fullName>
            <shortName evidence="8">GluRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">gltX</name>
        <name evidence="12" type="ORF">VDA_002628</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu)</text>
            <dbReference type="Rhea" id="RHEA:23540"/>
            <dbReference type="Rhea" id="RHEA-COMP:9663"/>
            <dbReference type="Rhea" id="RHEA-COMP:9680"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.17"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.17" evidence="8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300535.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002628"/>
    <dbReference type="EnsemblBacteria" id="EEZ41596">
        <property type="protein sequence ID" value="EEZ41596"/>
        <property type="gene ID" value="VDA_002628"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0008">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1409413at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004818">
        <property type="term" value="F:glutamate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006424">
        <property type="term" value="P:glutamyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00808">
        <property type="entry name" value="GluRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00022">
        <property type="entry name" value="Glu_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045462">
        <property type="entry name" value="aa-tRNA-synth_I_cd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020751">
        <property type="entry name" value="aa-tRNA-synth_I_codon-bd_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008925">
        <property type="entry name" value="aa_tRNA-synth_I_cd-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004527">
        <property type="entry name" value="Glu-tRNA-ligase_bac/mito"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000924">
        <property type="entry name" value="Glu/Gln-tRNA-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020058">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033910">
        <property type="entry name" value="GluRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19269">
        <property type="entry name" value="Anticodon_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00749">
        <property type="entry name" value="tRNA-synt_1c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00987">
        <property type="entry name" value="TRNASYNTHGLU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48163">
        <property type="entry name" value="SSF48163"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00464">
        <property type="entry name" value="gltX_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-synt_1c" evidence="10">
        <location>
            <begin position="3"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="Anticodon_2" evidence="11">
        <location>
            <begin position="329"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="8">
        <location>
            <begin position="9"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="8">
        <location>
            <begin position="240"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="243"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF19269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ41596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="474" mass="53521" checksum="BE522C1E51C30EF2" modified="2010-01-19" version="1">MTVKTRFAPSPTGFLHVGGARTALYSWLYAKHNNGEFVLRIEDTDLERSTQEAIDAIMEGMEWLELNWDEGPYYQTKRFDRYNAVVDQLLAEDKAYKCYCPKELLDEIREEQMAAGVKPRYDANHPKIIAANAAATEDSPFCIRFRNPKEGTVVFDDKIRGRIEIANSELDDLIIRRTDGSPTYNFCVVIDDWDMGITQVVRGEDHINNTPRQINIYKALGAPVPEFAHCAMILGDDGAKLSKRHGAVSVMQYRDEGYLPQALLNYLVRLGWSHGDQEIFSMQEMIDLFSLESVSKSASAFNTDKLLWLNNHYIKTAEPEYVAKYLQWHLDQKEISLENGPAITDVIKLVGERCNTLVELAEQSRYFYQDFDAFEEGAAKKHLRPVAKEALELALAKVEALTEWTTENLHAVIAQVCEELELGMGKVGMPLRVAVTGQGQSPSVDAVMQLIGKDRVVARIKMALEFIAAREANA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZD1</accession>
    <name>D0YZD1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Nitrate/nitrite response regulator protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_002644</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300586.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002644"/>
    <dbReference type="EnsemblBacteria" id="EEZ41612">
        <property type="protein sequence ID" value="EEZ41612"/>
        <property type="gene ID" value="VDA_002644"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="930905at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="5"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="141"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="208" mass="22634" checksum="E5358D5355FBE0A8" modified="2010-01-19" version="1">MSNWQIIIVDDHPLMRRGINQLLSFEPEFNVIGEASNGVDAVALALETNPDLILLDLNMKGMSGLDTLTAMRNEGISSTIVVLTVSDSRADIKALVAAGADGYLLKDTEPDELIALLHQALAGGEAYSSIVKEYLSDDLAQDSLLSTLTDRELQILQEVAKGHRNKQIADTLFISESTVKVHMKSLLKKLQVKSRTAATVLYLESLGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZF9</accession>
    <name>D0YZF9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Exodeoxyribonuclease 7 small subunit</fullName>
            <ecNumber evidence="3">3.1.11.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Exodeoxyribonuclease VII small subunit</fullName>
            <shortName evidence="3">Exonuclease VII small subunit</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">xseB</name>
        <name evidence="4" type="ORF">VDA_002672</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates.</text>
            <dbReference type="EC" id="3.1.11.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heterooligomer composed of large and small subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the XseB family.</text>
    </comment>
    <dbReference type="EC" id="3.1.11.6" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300667.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002672"/>
    <dbReference type="EnsemblBacteria" id="EEZ41640">
        <property type="protein sequence ID" value="EEZ41640"/>
        <property type="gene ID" value="VDA_002672"/>
    </dbReference>
    <dbReference type="GeneID" id="57341060"/>
    <dbReference type="eggNOG" id="COG1722">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2057189at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009318">
        <property type="term" value="C:exodeoxyribonuclease VII complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008855">
        <property type="term" value="F:exodeoxyribonuclease VII activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006308">
        <property type="term" value="P:DNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1040">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00337">
        <property type="entry name" value="Exonuc_7_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003761">
        <property type="entry name" value="Exonuc_VII_S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037004">
        <property type="entry name" value="Exonuc_VII_ssu_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34137">
        <property type="entry name" value="PTHR34137"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02609">
        <property type="entry name" value="Exonuc_VII_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006488">
        <property type="entry name" value="Exonuc_VII_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116842">
        <property type="entry name" value="SSF116842"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01280">
        <property type="entry name" value="xseB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="80" mass="8947" checksum="F384DA9AFFDDE168" modified="2010-01-19" version="1">MAAKKPENMAFEEALDELDLIVNELESGNIALEDALKKFERGIALARSSQQKLTQAEQRVEILLQADDEAPLTEFDVNDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZJ7</accession>
    <name>D0YZJ7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chaperone protein HscB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002710</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002710"/>
    <dbReference type="EnsemblBacteria" id="EEZ41678">
        <property type="protein sequence ID" value="EEZ41678"/>
        <property type="gene ID" value="VDA_002710"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1076">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001671">
        <property type="term" value="F:ATPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044571">
        <property type="term" value="P:[2Fe-2S] cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051259">
        <property type="term" value="P:protein complex oligomerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004640">
        <property type="entry name" value="HscB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036386">
        <property type="entry name" value="HscB_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009073">
        <property type="entry name" value="HscB_oligo_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14021">
        <property type="entry name" value="PTHR14021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07743">
        <property type="entry name" value="HSCB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47144">
        <property type="entry name" value="SSF47144"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00714">
        <property type="entry name" value="hscB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HSCB_C" evidence="2">
        <location>
            <begin position="50"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="134" mass="15756" checksum="0C69CC121FFA7561" modified="2010-01-19" version="1">MASERDRMMAMQKAAQINDAFQTLKNPISRAEYMLSERDEDIRGEQKTLQDMDFLMQQMELREALEAIAEQEEPESALADFDQQVSSMYRSYLQQLEQLLNQEQWPLAADCVRKLKFIAKLRDEVEQLEDKLFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZK8</accession>
    <name>D0YZK8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">S-adenosylmethionine:tRNA ribosyltransferase-isomerase</fullName>
            <ecNumber evidence="5">2.4.99.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Queuosine biosynthesis protein QueA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">queA</name>
        <name evidence="6" type="ORF">VDA_002721</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>7-aminomethyl-7-carbaguanosine(34) in tRNA + S-adenosyl-L-methionine = adenine + epoxyqueuosine(34) in tRNA + H(+) + L-methionine</text>
            <dbReference type="Rhea" id="RHEA:32155"/>
            <dbReference type="Rhea" id="RHEA-COMP:10342"/>
            <dbReference type="Rhea" id="RHEA-COMP:10346"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:82833"/>
            <dbReference type="ChEBI" id="CHEBI:82834"/>
            <dbReference type="EC" id="2.4.99.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">tRNA modification; tRNA-queuosine biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the QueA family.</text>
    </comment>
    <dbReference type="EC" id="2.4.99.17" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002721"/>
    <dbReference type="EnsemblBacteria" id="EEZ41689">
        <property type="protein sequence ID" value="EEZ41689"/>
        <property type="gene ID" value="VDA_002721"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0809">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00392"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051075">
        <property type="term" value="F:S-adenosylmethionine:tRNA ribosyltransferase-isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:queuosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00113">
        <property type="entry name" value="QueA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003699">
        <property type="entry name" value="QueA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042118">
        <property type="entry name" value="QueA_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042119">
        <property type="entry name" value="QueA_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036100">
        <property type="entry name" value="QueA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30307">
        <property type="entry name" value="PTHR30307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02547">
        <property type="entry name" value="Queuosine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111337">
        <property type="entry name" value="SSF111337"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00113">
        <property type="entry name" value="queA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 5" id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5 6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="351" mass="39063" checksum="874CFC33DEE8CDC9" modified="2010-01-19" version="1">MMQVSDFDFDLPDELIARYPQPERTSSRLLQLDGNSGDIAHKTFKDVLDLVNPGDLMIFNNTRVIPARMFGRKASGGKLEVLVERMLDEKSILAHVRASKSPKPGTELLLGENDEYSAEMVARHDALFEIRFNSDKTVLEILDEVGHMPLPPYIDRPDEDADKERYQTVYNAKPGAVAAPTAGLHFDDALLAALKEKGVNFAFVTLHVGAGTFQPVRVDNIDDHHMHSEYVEVPEEVVTAINETKANGGRVVAVGTTSVRSLESAAQDAVKNGTELKPFFGDTEIFIFPGYQFQLVDVLITNFHLPESTLIMLVSAFAGYEHTMNAYKDAVANQFRFFSYGDSMFVTRKTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZR2</accession>
    <name>D0YZR2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">DNA repair protein RecN</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4 5">Recombination protein N</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_002775</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 5">May be involved in recombinational repair of damaged DNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the RecN family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300970.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002775"/>
    <dbReference type="EnsemblBacteria" id="EEZ41743">
        <property type="protein sequence ID" value="EEZ41743"/>
        <property type="gene ID" value="VDA_002775"/>
    </dbReference>
    <dbReference type="GeneID" id="57340948"/>
    <dbReference type="eggNOG" id="COG0497">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1074831at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004604">
        <property type="entry name" value="DNA_recomb/repair_RecN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11059">
        <property type="entry name" value="PTHR11059"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003128">
        <property type="entry name" value="RecN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00634">
        <property type="entry name" value="recN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMC_N" evidence="7">
        <location>
            <begin position="1"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="336"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00033408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR003128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ41743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="555" mass="62212" checksum="513E441949B58F8C" modified="2010-01-19" version="1">MLSHMTISNFAIVKTLEFELKSGMTTITGETGAGKSIAIDALGLCLGDRAEASMVRPNEDKADISATFSLNNNQSARRWLEDNELIDGEECILRRVITKEGRSRGFINGSPVPVSMQKSLGQLLINIHGQHAHQQLMRPEYQQQMLDQYAGHHLLMEHTREAYQRWRQAHNELKRLTQSREENEAQKQLIQYQVKELDELSLGEDEFDEIEEEHKRLSNSGELAVSSQTALSMLYDNDDGNALQMLQMASQQVCNLGEFDSSLSAIPQMLEDAIIQVQEASQELRCYLDNLDMDPHRLIYLEERLAKIMSLARKHYVMPNELYQKHQDLLKELENLDCSDERLDEMAQNVELLRQECLAAAEKLSKSRERYAKELSCKISESMHQLSMENGQFCIDIQADPERMLSPLGFDNITFLVSTNPGQPLQPLGKVASGGELSRISLAIQVITAQKVETPSLIFDEVDVGISGPTAAIVGKMLRKLGESTQVMCVTHLPQVAGCGHQQMFVAKKSSEGQTETNMRPLTVDERVAELARLLGGSEITERTLANAKELLVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZT3</accession>
    <name>D0YZT3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Histidine--tRNA ligase</fullName>
            <ecNumber evidence="5">6.1.1.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Histidyl-tRNA synthetase</fullName>
            <shortName evidence="5">HisRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">hisS</name>
        <name evidence="7" type="ORF">VDA_002796</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>ATP + L-histidine + tRNA(His) = AMP + diphosphate + H(+) + L-histidyl-tRNA(His)</text>
            <dbReference type="Rhea" id="RHEA:17313"/>
            <dbReference type="Rhea" id="RHEA-COMP:9665"/>
            <dbReference type="Rhea" id="RHEA-COMP:9689"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78527"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.21"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3 5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.21" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301032.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002796"/>
    <dbReference type="EnsemblBacteria" id="EEZ41764">
        <property type="protein sequence ID" value="EEZ41764"/>
        <property type="gene ID" value="VDA_002796"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0124">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="277998at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004821">
        <property type="term" value="F:histidine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006427">
        <property type="term" value="P:histidyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00773">
        <property type="entry name" value="HisRS-like_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00127">
        <property type="entry name" value="His_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015807">
        <property type="entry name" value="His-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041715">
        <property type="entry name" value="HisRS-like_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004516">
        <property type="entry name" value="HisRS/HisZ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43707">
        <property type="entry name" value="PTHR43707"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13393">
        <property type="entry name" value="tRNA-synt_His"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001549">
        <property type="entry name" value="His-tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00442">
        <property type="entry name" value="hisS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="6">
        <location>
            <begin position="1"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="419" mass="48242" checksum="505CD549B1B2D36D" modified="2010-01-19" version="1">MDIKSIRGMKDILPTETPIWQWVEKVLRKATKNYGYKEIRLPILEPIELFQRAVGEATDIVSKEMYDFIDKSNEHITLRPEGTSGCVRSVIENNLCYNNTQRLWYQGPMFRYERPQKGRLRQFNQFGVETFGMSNADIDSELIYLSNEIFSALGLTKHINLEINSLGTIEERLEHRKALINYFKKHQDLLDEDSLIRLEKNPLRILDSKNPQMQTMLENAPKLLDYLTEESLDHFKTVCSNLDQVDIKYTINPRLVRGLDYYTRTVFEWTTDQLGSQSTVCGGGRYDGLVALFSGQSLPASGFAIGIERLILLLEAVNITPPHDSSKKIIFTCEDKLDTNKALILAKNLRDTFPQLEVYSDFSGSKLKKQHQRALKESADIVVTLNVDHTLGIWSISDNDKLVINKEEFLDHIQIFIKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZT9</accession>
    <name>D0YZT9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Energy-dependent translational throttle protein EttA</fullName>
            <ecNumber evidence="7">3.6.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Translational regulatory factor EttA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ettA</name>
        <name evidence="10" type="ORF">VDA_002802</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="7">Associates with ribosomes and polysomes.</text>
    </comment>
    <comment type="domain">
        <text evidence="7">The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.</text>
    </comment>
    <comment type="domain">
        <text evidence="7">The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.-" evidence="7"/>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="gene ID" value="VDA_002802"/>
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        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="term" value="P:negative regulation of translational elongation"/>
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        <property type="entry name" value="AAA+_ATPase"/>
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        <property type="entry name" value="ABC_tran_Xtn"/>
    </dbReference>
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        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
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        <property type="entry name" value="ABC_transporter-like_CS"/>
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        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
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        <property type="entry name" value="ABC_ABC_ChvD"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="6 7" id="KW-0810">Translation regulation</keyword>
    <keyword evidence="2 7" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="1"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="298"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="region of interest" description="Arm" evidence="7">
        <location>
            <begin position="69"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="PtIM" evidence="7">
        <location>
            <begin position="216"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7 8">
        <location>
            <begin position="13"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7 8">
        <location>
            <begin position="330"/>
            <end position="337"/>
        </location>
    </feature>
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        <source>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ41770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="529" mass="59300" checksum="DC446486A780E18D" modified="2010-01-19" version="1">MSFFPGAKIGVLGLNGAGKSTLLRIMAGIDTDIEGEARPQPGLKIGYLPQEPVLDEEKTVREVVEESVSDVKEALIRLDQVYAAYAEPDADFDALAKEQGDLEALIETKDGHNLGMQLERAADALRLPEWDAKIKHLSGGERRRVAICRLLLDKPDMLLLDEPTNHLDAESVAWLEHFLVEYSGTVVAITHDRYFLDNAAGWILELDRGEGIPWQGNYSSWLEQKDARLKQEASQERALQKTIEKELEWVRQNPKGRQAKSKARMARFEELQSNDHQKRNETNELFIPPGERLGDKVIEVKNLTKSFGDRVLIDDLSFSMPKGAIVGIIGANGAGKSTLFKMLSGKEQPDSGTIELGETVSLASVDQFRDSMNDNNTVYQEISEGADIIKINSFEIPARAYVSRFNFKGSDHQKRIGDLSGGERNRVHLAKLLKAGGNVLLLDEPTNDLDVETLRALEEALLEFPGCAMVISHDRWFLDRIATHILDYRDEGQVNFFEGNFTEYADWLKKTLGSDAAEPHRIKYKRIAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZW6</accession>
    <name>D0YZW6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Polyribonucleotide nucleotidyltransferase</fullName>
            <ecNumber evidence="7">2.7.7.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Polynucleotide phosphorylase</fullName>
            <shortName evidence="7">PNPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pnp</name>
        <name evidence="9" type="ORF">VDA_002829</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>phosphate + RNA(n+1) = a ribonucleoside 5'-diphosphate + RNA(n)</text>
            <dbReference type="Rhea" id="RHEA:22096"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the polyribonucleotide nucleotidyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.8" evidence="7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002829"/>
    <dbReference type="EnsemblBacteria" id="EEZ41797">
        <property type="protein sequence ID" value="EEZ41797"/>
        <property type="gene ID" value="VDA_002829"/>
    </dbReference>
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        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004654">
        <property type="term" value="F:polyribonucleotide nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006402">
        <property type="term" value="P:mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01595">
        <property type="entry name" value="PNPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015847">
        <property type="entry name" value="ExoRNase_PH_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012162">
        <property type="entry name" value="PNPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015848">
        <property type="entry name" value="PNPase_PH_RNA-bd_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11252">
        <property type="entry name" value="PTHR11252"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03726">
        <property type="entry name" value="PNPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03725">
        <property type="entry name" value="RNase_PH_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005499">
        <property type="entry name" value="PNPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="SSF54791"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="SSF55666"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03591">
        <property type="entry name" value="polynuc_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 7 9" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="S1 motif" evidence="8">
        <location>
            <begin position="621"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="485"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="491"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="706" mass="77082" checksum="8D15AB26664300F9" modified="2010-01-19" version="1">MNPIVKTFQYGNHTVTLETGVMARQATAAVMASMDDTSVFVSVVGKKEAVEGQDFFPLTVNYQERTYAAGKIPGGFFKREGRPSEGETLTARLIDRPIRPLFPDAFKNEVQVIATVVSVNPNVSPDIITMIGTSAALAISGIPFNGPIGAARVGFINDQFVLNPSNVELEESRLDLVVAGTKDAVLMVESEADRLSEEQMLQAVVFGHDQQQTVINAINEFAAEVATPAWDWIAPEENTVLKNKIAELAEAKLVEAYQITEKMARYDRIHEIADEVNEVLLSEDLEVNTKEVHTIFHDLEKTVVRRSIIAGNPRIDGREVDMVRALDVRTGVLPRTHGSSLFTRGETQALVTATLGTQRDAQIIDELTGEKKDYFLLHYNFPPYCVGETGFVGSPKRREIGHGRLAKRGIAAVMPSIDEFPYTVRVVSEITESNGSSSMASVCGTSLALMDAGVPIKSSVAGIAMGLVKEGDDFVVLSDILGDEDHLGDMDFKVAGTDDGITALQMDIKIEGITKEIMQIALNQAKGARMHILSVMDNAINAPRDDISEFAPRIHTMKINPEKIKDVIGKGGAVIRALTEETGTTIEIEDDGTVKIAATDGLQAKEAIRRIEEITADVEVGRIYTGKVTRIVDFGAFVSVIGTKEGLVHISQISQERVEKVSDYLKEGQEVPVKVLEIDRQGRIRLSMKEAVQPAEQPAQDEQPKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZZ6</accession>
    <name>D0YZZ6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Probable membrane transporter protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_002859</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301221.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002859"/>
    <dbReference type="EnsemblBacteria" id="EEZ41827">
        <property type="protein sequence ID" value="EEZ41827"/>
        <property type="gene ID" value="VDA_002859"/>
    </dbReference>
    <dbReference type="GeneID" id="57340853"/>
    <dbReference type="eggNOG" id="COG0730">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="881796at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002781">
        <property type="entry name" value="TM_pro_TauE-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01925">
        <property type="entry name" value="TauE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="111"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="151"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="184"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="218"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="249"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ41827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="268" mass="27529" checksum="55C700CF594C9B28" modified="2010-01-19" version="1">MLENALWLFGMCLLVGSSVGFLAGLLGIGGGLVVVPALVWLLPHAGISSNLVMHIALGTSLASIVLTSGASARNHIRLGNVDYSIVKALAPGVVLGGFGGSFIAEIVPTELLPKIFATIVLTLAIQMLLSMRLGRKEQRLPSTVACASSGAVIGVISSLAGIGGGSLTVPYLSWHGVEMRKAIGCASFAGAMIAIAGMIGFITAGVGSESLPPYSLGYVYLPALLGIVTTSVITTRYGAALVSRLPTVTLKKIFAVFLLFISVKMFLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0B1</accession>
    <name>D0Z0B1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">LPS-assembly protein LptD</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">lptD</name>
        <name evidence="5" type="ORF">VDA_002974</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the LptD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301443.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002974"/>
    <dbReference type="EnsemblBacteria" id="EEZ41942">
        <property type="protein sequence ID" value="EEZ41942"/>
        <property type="gene ID" value="VDA_002974"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1452">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="100018at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043165">
        <property type="term" value="P:Gram-negative-bacterium-type cell outer membrane assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015920">
        <property type="term" value="P:lipopolysaccharide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010033">
        <property type="term" value="P:response to organic substance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01411">
        <property type="entry name" value="LPS_assembly_LptD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020889">
        <property type="entry name" value="LipoPS_assembly_LptD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007543">
        <property type="entry name" value="LptD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005653">
        <property type="entry name" value="OstA-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04453">
        <property type="entry name" value="LptD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03968">
        <property type="entry name" value="LptD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5009009109" description="LPS-assembly protein LptD" evidence="2">
        <location>
            <begin position="24"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="domain" description="OstA-like_N" evidence="3">
        <location>
            <begin position="68"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="LptD" evidence="4">
        <location>
            <begin position="312"/>
            <end position="693"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="782" mass="88773" checksum="D02011313D1C673B" modified="2010-01-19" version="1" precursor="true">MSLTSRSLLATMISLALYGPAMANELSAPSDKVKDEHTVAQADEPKVVRGVCIAPQDRQEDTNNLPVKITADSAEAINEKKITYKGDVIVKQGTRTIVADQASLKQPENVVTATGDVYLHDGGIEVDAKRITSNLDTQNSEMDDAIYNMTCQPGRGDAAQIIKTNVDGTQFYKMKDGTYTTCPAKDKSWRFSASSLERDGESPFADLYNARFEVLDVPVFYLPYLRVPVTDQRLTGFLYPSIGYGSRDGFELETPFYWNIAPNYDLTLTPKYMSNRGLQLDSQFRYLTELGQGSLKGEYLNSDKLYKDKGARWAFNWEHKGIYNQHWLFDIDYSKASDFQYFSDLDSDIGNREDNNLLQTADVSYRDTNWDSTLRVRDFQPLTADGQGNQYRLMPQFDLNYYQQDLPYNLEFKVNSSVSRFDNDSKAKPTADRFYIAPSLVLPYATPWWTVTSEAKLMYTHYNQDARNSGLNDLKESVDRTIPEFRIHSGLYFERNTSILGEDYVQSLEPQIQYLYIKDVDQKDIYNPFDYSGGGYDSTRLQQDYYGLFSDRTYSGIDYIAPANQVTIGASTRYFDSNYKERFTLSLGQIFYINKPTAEGNQDAQSYSATALETEFNLADSLFLKSSMQYDASDNDIQMASGAIEYRANGMYIQPNYRYVSNTYLDKYVKNPNKDNDGISQIGLSTGFPLYDNIYVKADYFQDLNVNKMIESQVGVTYRSACWMIGLNYNRYAKNSLGNDFTEYDSNVSISFSLLGLQGVKPFGSTDDGNALSYGNSFSLNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0H9</accession>
    <name>D0Z0H9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_003043</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301674.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003043"/>
    <dbReference type="EnsemblBacteria" id="EEZ42010">
        <property type="protein sequence ID" value="EEZ42010"/>
        <property type="gene ID" value="VDA_003043"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0471">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="626718at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001898">
        <property type="entry name" value="SLC13A/DASS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00939">
        <property type="entry name" value="Na_sulph_symp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00785">
        <property type="entry name" value="dass"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="101"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="146"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="187"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="229"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="272"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="298"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="324"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="363"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="410"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="451"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ42010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="471" mass="50818" checksum="1F18753AF1D9B1A9" modified="2010-01-19" version="1">MKRFPVARLIKLLIAFGIPLLVLMMPIDNIPLENLTLIQHRLLAIFLLAALLWVLEPVPVFATSILIIALELIMISDKGLHWFRQPPTGHEMGDMLAYTDIFGAFSSPIIILFMGGFALAIAASKYELDNNLARVLLKPFGQQPRFIMLGLMLITAVFSMFMSNTATTVMMLALLAPIIASVPKGDIGIKALVLCIPIAANTGGIATPIGTPPNAIALQYLTGENTISFLDWMMMGLPFVIVQLAFAWWLLQKLFPSSQPTMTLQLNGQFQTSWQAIVVYATFALTILLWMTTALHGMNSYVVAIIPLAIFTLTGIMGKEELKLINWDVLWLVAGGIAIGLGLDKTGLAKELAHAIDYNTLTPFAVVLSLSLICWLMANFMSNTATANLLMPIAAAVTTSMESLSSMGGLQGVLIVVAFSASLGMILPVSTPPNSLAYSTGLIETKDMAKAGIIIGLVGLAIVYLALLILN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0M1</accession>
    <name>D0Z0M1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Hemolysin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">VDA_003085</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301815.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003085"/>
    <dbReference type="EnsemblBacteria" id="EEZ42052">
        <property type="protein sequence ID" value="EEZ42052"/>
        <property type="gene ID" value="VDA_003085"/>
    </dbReference>
    <dbReference type="GeneID" id="57340437"/>
    <dbReference type="eggNOG" id="COG1253">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1155802at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04590">
        <property type="entry name" value="CBS_pair_CorC_HlyC_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002550">
        <property type="entry name" value="CNNM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044751">
        <property type="entry name" value="Ion_transp-like_CBS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01595">
        <property type="entry name" value="DUF21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51846">
        <property type="entry name" value="CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0129">CBS domain</keyword>
    <keyword evidence="5 7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="119"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="CNNM transmembrane" evidence="10">
        <location>
            <begin position="1"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="9">
        <location>
            <begin position="262"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ42052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="351" mass="39302" checksum="05E62096A0DFDCE8" modified="2010-01-19" version="1">MILLTVYITTAIGVSFVCSVLEAVLLSISPSYIATLRQQNHPAAEKLTALKDNIDRPLASILTLNTIAHTIGAATAGAQATIVFGSEWLGVFSGVLTIAILLLSEIVPKTIGATYWRQLAPMSATLLRWMVIMLIPLVWMSEQITRRLSRGHEQPKLRDEISAMALLAHENGELAEGESKILTNLLQFRDVSVTKIMTPRPVLFRVNAEQSINEFLSMHKESPFSRPLVYSEQNDNIVGFVHRLELFAESQAGRGQKELGTLMRPLPIVMNTFSVPQAFERLMKERSQLTLVVDEYGTVQGLVTLEDIFESLVGEEIVDEADKNTDMQQLAFQRWEKWKRTHGVIENKDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0N1</accession>
    <name>D0Z0N1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">50S ribosomal protein L1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rplA</name>
        <name evidence="10" type="ORF">VDA_003095</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.</text>
    </comment>
    <comment type="function">
        <text evidence="8">Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8 9">Belongs to the universal ribosomal protein uL1 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301845.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003095"/>
    <dbReference type="EnsemblBacteria" id="EEZ42062">
        <property type="protein sequence ID" value="EEZ42062"/>
        <property type="gene ID" value="VDA_003095"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0081">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1671455at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00403">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01318_B">
        <property type="entry name" value="Ribosomal_L1_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005878">
        <property type="entry name" value="Ribosom_L1_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002143">
        <property type="entry name" value="Ribosomal_L1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023674">
        <property type="entry name" value="Ribosomal_L1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028364">
        <property type="entry name" value="Ribosomal_L1/biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016095">
        <property type="entry name" value="Ribosomal_L1_3-a/b-sand"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023673">
        <property type="entry name" value="Ribosomal_L1_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00687">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002155">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56808">
        <property type="entry name" value="SSF56808"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01169">
        <property type="entry name" value="rplA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01199">
        <property type="entry name" value="RIBOSOMAL_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0678">Repressor</keyword>
    <keyword evidence="7 8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6 8 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 8" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="4 8" id="KW-0810">Translation regulation</keyword>
    <keyword evidence="8" id="KW-0820">tRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ42062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="234" mass="24855" checksum="52E64399E408F17E" modified="2010-01-19" version="1">MAKLTKRMRVIREKVDVTREYDINEAVALLKELATAKFVESVDVAVNLGIDARKSDQNVRGATVLPNGTGRDIRVAVFTQGANAEAAKEAGAELVGMEDLAEQVKKGEMNFDVVIASPDAMRVVGQLGTILGPRGLMPNPKVGTVTPNVAEAVKNAKAGQVRYRNDKNGIIHTTIGKVSFDAAQLKENLEALLVALKRAKPSSAKGTFIKKVSISTTMGAGVAVDQNTLETNAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-06-02" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0P1</accession>
    <name>D0Z0P1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003105</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ42072">
        <property type="protein sequence ID" value="EEZ42072"/>
        <property type="gene ID" value="VDA_003105"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="SSF54928"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="40" mass="4568" checksum="E91D0C48368358B6" modified="2010-01-19" version="1">MASQEAELAVDKLNNKEYGQRTLKVREANEPKNMDNSDTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0R2</accession>
    <name>D0Z0R2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Phosphoenolpyruvate carboxykinase (ATP)</fullName>
            <shortName evidence="10">PCK</shortName>
            <shortName evidence="10">PEP carboxykinase</shortName>
            <shortName evidence="10">PEPCK</shortName>
            <ecNumber evidence="4 10">4.1.1.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">pckA</name>
        <name evidence="11" type="ORF">VDA_003126</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>ATP + oxaloacetate = ADP + CO2 + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:18617"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.1.1.49"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="10">Binds 1 Mn(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.49" evidence="4 10"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003126"/>
    <dbReference type="EnsemblBacteria" id="EEZ42093">
        <property type="protein sequence ID" value="EEZ42093"/>
        <property type="gene ID" value="VDA_003126"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1866">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004612">
        <property type="term" value="F:phosphoenolpyruvate carboxykinase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00484">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.449.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.228.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00453">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001272">
        <property type="entry name" value="PEP_carboxykinase_ATP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013035">
        <property type="entry name" value="PEP_carboxykinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008210">
        <property type="entry name" value="PEP_carboxykinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015994">
        <property type="entry name" value="PEPCK_ATP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30031">
        <property type="entry name" value="PTHR30031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01293">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006294">
        <property type="entry name" value="PEP_crbxkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68923">
        <property type="entry name" value="SSF68923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00224">
        <property type="entry name" value="pckA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00532">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 10" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="5 10" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="11" id="KW-0418">Kinase</keyword>
    <keyword evidence="9 10 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-0464">Manganese</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="10">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="202"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="221"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="237"/>
            <end position="245"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="258"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="286"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="322"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="438"/>
            <end position="439"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="444"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ42093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="530" mass="58526" checksum="F8FE5F77057C7547" modified="2010-01-19" version="1">MDLSQYGIKNVTEVVRNPSYEMLFEEETKPGLEGYEKGVVTELGAVAVDTGIFTGRSPKDKFIVKDDTTRDTMWWADQGTNDNKALGQEAWNDLKALVTDQLSGKRLFVVDGYCGANPDTRLCIRVITEVAWQAHFVKNMFIRPTEAELEGFEPDFVIMNGSKCTNPKWEEHGMNSENFTVFNLSEKMQLIGGTWYGGEMKKGMFAMMNYFLPLRDIASMHCSANMGENGDVAVFFGLSGTGKTTLSTDPKRALIGDDEHGWDDHGVFNFEGGCYAKTINLSKEAEPDIYNAIRRDALLENVTVRGDGSIDFNDGSKTENTRVSYPIYHIDNIVKPVSKGGHANKVIFLSADAFGVLPPVSKLTPEQTKYHFLSGFTAKLAGTERGITEPTPTFSACFGNAFLTLHPTKYAEVLVKRMEAAGAEAYLVNTGWNGTGKRISIQDTRGIIDAILDGSIDKAQTKHIPIFNLEVPTALPGVDSNILDPRDTYTDPLQWESKAKDLAERFVNNFDKYTDTTEGANLVAAGPQLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0S5</accession>
    <name>D0Z0S5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Signal transduction protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_003139</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301977.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003139"/>
    <dbReference type="EnsemblBacteria" id="EEZ42106">
        <property type="protein sequence ID" value="EEZ42106"/>
        <property type="gene ID" value="VDA_003139"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2905">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="301791at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008773">
        <property type="term" value="F:[protein-PII] uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018821">
        <property type="entry name" value="DUF294_put_nucleoTrafse_sb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005105">
        <property type="entry name" value="GlnD_Uridyltrans_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03445">
        <property type="entry name" value="DUF294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10335">
        <property type="entry name" value="DUF294_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0129">CBS domain</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="2">
        <location>
            <begin position="18"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="3">
        <location>
            <begin position="161"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="3">
        <location>
            <begin position="226"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ42106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="620" mass="70573" checksum="6DE96D945F5A5F80" modified="2010-01-19" version="1">MDETLVPNIVDFISHIDPFDKLPKVALVEVAQSIKISYLAAKSEIQFDQKDQEQYLYLIRSGTVEQRHPNGTLRARLEQEDLFGFTHLADSAEHEPYQAITLTACLLYLIPVSKLNSILAQYPEQAQHFATAAQTRLESALNVVWSDAEKGLFVETVADVAQRHPAIVDSKMSIKEVARIMRYQHHSSCAVIIENQQIIGIITDRDMTKRVIADGVSTDAPITQVMTRHPYTIGSQDLVLKAVGLMMEHNIRSLPVVDNQQVVGLLTTSDLVRKHRVQAIFLIEKINHAQTVEALAQLTAERQAIYEALVEGHVQPAVIGQVMAMIMDAINRRLITFAEQKLGPPPCPYAWVVAGSHARNEVHILSDQDSAIIFSDHSQPQDKTYFNYLAMFVCNGLAACGYPLCTGRFMAAKPQWCQPMRIWREYYRKWVASPEYDKLLNVSVFFEIRTVYGEDDFAQQLRQELYNHIDEHPQFLSSLVRNALTVKPPLGIFNNLVLEHNGSNSKSLNIKKYAINIMVDLARVYALAAQSDAMTTEQRFIDAHQHAIINKNTLDDLLGAYRFMLQLRQHHQWQALKQGNTPDNYIDPNQFGSFERKHLKDAFRIVANLQEICKMRFIRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0U2</accession>
    <name>D0Z0U2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Diaminopimelate decarboxylase</fullName>
            <shortName evidence="3">DAP decarboxylase</shortName>
            <shortName evidence="3">DAPDC</shortName>
            <ecNumber evidence="3 4">4.1.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">lysA</name>
        <name evidence="7" type="ORF">VDA_003156</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 4">
            <text>H(+) + meso-2,6-diaminoheptanedioate = CO2 + L-lysine</text>
            <dbReference type="Rhea" id="RHEA:15101"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:57791"/>
            <dbReference type="EC" id="4.1.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 3 4">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 4">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; L-lysine from DL-2,6-diaminopimelate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.20" evidence="3 4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302027.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003156"/>
    <dbReference type="EnsemblBacteria" id="EEZ42123">
        <property type="protein sequence ID" value="EEZ42123"/>
        <property type="gene ID" value="VDA_003156"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0019">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="861683at2"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00027"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008836">
        <property type="term" value="F:diaminopimelate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06828">
        <property type="entry name" value="PLPDE_III_DapDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02120">
        <property type="entry name" value="LysA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009006">
        <property type="entry name" value="Ala_racemase/Decarboxylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002986">
        <property type="entry name" value="DAP_deCOOHase_LysA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022643">
        <property type="entry name" value="De-COase2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022657">
        <property type="entry name" value="De-COase2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022644">
        <property type="entry name" value="De-COase2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022653">
        <property type="entry name" value="De-COase2_pyr-phos_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000183">
        <property type="entry name" value="Orn/DAP/Arg_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02784">
        <property type="entry name" value="Orn_Arg_deC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00278">
        <property type="entry name" value="Orn_DAP_Arg_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01181">
        <property type="entry name" value="DAPDCRBXLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01179">
        <property type="entry name" value="ODADCRBXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50621">
        <property type="entry name" value="SSF50621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="SSF51419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01048">
        <property type="entry name" value="lysA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00878">
        <property type="entry name" value="ODR_DC_2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00879">
        <property type="entry name" value="ODR_DC_2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2 3 4" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="3 4 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="3 4" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orn_DAP_Arg_deC" evidence="5">
        <location>
            <begin position="31"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="domain" description="Orn_Arg_deC_N" evidence="6">
        <location>
            <begin position="36"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="3">
        <location>
            <begin position="275"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="240"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="278"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="314"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="318"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="345"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="372"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="3">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ42123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="417" mass="45956" checksum="92FC0EEE8E3AE462" modified="2010-01-19" version="1">MDYFNYQQDGQLWAEQVSAQSLAAQYGTPLYVYSRATLERHWQAFDRAVASHPHLICYAVKANSNLAVLNVLAKLGSGFDIVSLGELERVIAAGGDPSKVVFSGVGKTVAEMTRALSLGIKCFNVESEPELERLNQVAAELGVIAPISLRINPDVDAKTHPYISTGLRDNKFGITFERALDVYRLAHRLPNLNVVGMDCHIGSQLTEITPFIDAVDRLLSLIDTLADEGITIAHLDVGGGLGVTYDQEQPPEPSDYAIALLERLNQYPELELIFEPGRAIAANAGILLTRVEYLKHSEYKNFAIVDAAMNDLIRPTLYSAWQAIIPASPRQGEMQTYDIVGPICETGDFIGRDRQLALEPNDLLAVRSAGAYGFVMASNYNTRARAAEVMVDGEQSYLVRQRETLQQLWQGESLLPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0X6</accession>
    <name>D0Z0X6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptide ABC transporter peptide-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_003190</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302114.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003190"/>
    <dbReference type="EnsemblBacteria" id="EEZ42157">
        <property type="protein sequence ID" value="EEZ42157"/>
        <property type="gene ID" value="VDA_003190"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0747">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="162819at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030678">
        <property type="entry name" value="Peptide/Ni-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002741">
        <property type="entry name" value="MppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018793" evidence="1">
        <location>
            <begin position="24"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="domain" description="SBP_bac_5" evidence="2">
        <location>
            <begin position="66"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ42157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="519" mass="58012" checksum="BE330FFF7E4456A8" modified="2010-01-19" version="1">MKTLKSKLVVALMAAGLSMSALAAEVKVGYASDPVSLDPHEQLSGGTLQFSHMAFDPLVRFTQKMEFEPRLAQSWQRIDDHTFRFTLRQGVKFHSGNTMTADDVIWTFNRLQDSPDFKAIFEPYSEMKKVDDYTVDLISKDTYPLVLQTATYIFPMDSKFYSGKTEDGKDKAEVVKHGNSFASTHVSGTGPFTVTGREQGVKLEFARFADYWDKDSKGNVDKITILPIKEDATRVAALLSGGVDMIHPVAPNDHKRIKEASDIDLVTLPGTRIISFQMNQNSNEALKDPRVRQAIVHAINNEGIVKKIMKGFATAANQQGPEGYQGYTPELVGRYDLKKAKALMKEAGYEKGFNLSMIAPNNRYVNDAKVAQATAAMLSKIGIKVDLKTMPKAQYWPEFDKCAADMLMIGWHSDTEDSANLTEFLTMTRNTETGKGQYNCGFYSNPEVDQLVEAANKETDMAKRKEMLQKVETLLYKDAAFVPLHWQSEAWGARSNVHAAEIVNPMVMPYFGDLVVDKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z122</accession>
    <name>D0Z122_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="11 12">ATP synthase subunit a</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">ATP synthase F0 sector subunit a</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">F-ATPase subunit 6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">atpB</name>
        <name evidence="13" type="ORF">VDA_003236</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11 12">Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11 12">Cell membrane</location>
            <topology evidence="11 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11 12">Belongs to the ATPase A chain family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302250.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003236"/>
    <dbReference type="EnsemblBacteria" id="EEZ42203">
        <property type="protein sequence ID" value="EEZ42203"/>
        <property type="gene ID" value="VDA_003236"/>
    </dbReference>
    <dbReference type="GeneID" id="57340357"/>
    <dbReference type="eggNOG" id="COG0356">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="867266at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045263">
        <property type="term" value="C:proton-transporting ATP synthase complex, coupling factor F(o)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01393">
        <property type="entry name" value="ATP_synth_a_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045082">
        <property type="entry name" value="ATP_syn_F0_a_bact/chloroplast"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000568">
        <property type="entry name" value="ATP_synth_F0_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023011">
        <property type="entry name" value="ATP_synth_F0_asu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035908">
        <property type="entry name" value="F0_ATP_A_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42823">
        <property type="entry name" value="PTHR42823"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00119">
        <property type="entry name" value="ATP-synt_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00123">
        <property type="entry name" value="ATPASEA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81336">
        <property type="entry name" value="SSF81336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01131">
        <property type="entry name" value="ATP_synt_6_or_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00449">
        <property type="entry name" value="ATPASE_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 11 12" id="KW-0138">CF(0)</keyword>
    <keyword evidence="6 11 12" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 11 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="28"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="90"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="200"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="228"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ42203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="261" mass="28868" checksum="CEBAC62B5681D32C" modified="2010-01-19" version="1">MAAPGEALTPSGYITHHLTNLAVGNGGFWTVHLDSLFFSVLTGLAFLWLFRKAAKQATSGVPSKLQCFVEIMVEFVDSNVKETFHGRNPLIAPLALTIFCWILLMNIMDLVPIDFLPYAASSLGIPYLKVVPSADVNITMAMALGVFALMIYYSIKVKGLGGFAKELALHPFNHPVMIPFNLLLEVVSLLAKPLSLGMRLFGNMFAGEVVFILIAALMPWWAQWLGSLPWAIFHILVITIQAFVFMMLTIVYLSQAHEDNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z129</accession>
    <name>D0Z129_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 13">Membrane protein insertase YidC</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12 13">Foldase YidC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11 13">Membrane integrase YidC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Membrane protein YidC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">yidC</name>
        <name evidence="16" type="ORF">VDA_003243</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cell membrane</location>
            <topology evidence="13">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302266.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003243"/>
    <dbReference type="EnsemblBacteria" id="EEZ42210">
        <property type="protein sequence ID" value="EEZ42210"/>
        <property type="gene ID" value="VDA_003243"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0706">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="524437at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032977">
        <property type="term" value="F:membrane insertase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01810">
        <property type="entry name" value="YidC_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019998">
        <property type="entry name" value="Membr_insert_YidC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028055">
        <property type="entry name" value="Membr_insert_YidC/Oxa1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028053">
        <property type="entry name" value="Membr_insert_YidC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001708">
        <property type="entry name" value="YidC/ALB3/OXA1/COX18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038210">
        <property type="entry name" value="YidC_periplasmic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038221">
        <property type="entry name" value="YidC_periplasmic_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12428">
        <property type="entry name" value="PTHR12428"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02096">
        <property type="entry name" value="60KD_IMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14849">
        <property type="entry name" value="YidC_periplas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00701">
        <property type="entry name" value="60KDINNERMP"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01900">
        <property type="entry name" value="YIDCPROTEIN"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03593">
        <property type="entry name" value="yidC_nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03592">
        <property type="entry name" value="yidC_oxa1_cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 13" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10 13" id="KW-0143">Chaperone</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 13" id="KW-0653">Protein transport</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 13" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="339"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="413"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="460"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="490"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="domain" description="YidC_periplas" evidence="15">
        <location>
            <begin position="66"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="28"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00033245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00033342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF14849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EEZ42210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="540" mass="60676" checksum="7DD0D7071928381D" modified="2010-01-19" version="1">MDSQRNILLIALLFVSFLLFQQWNSDKNPQPQSQGVAQQVNNSGDVPSHSADGQLVTDQSSSQNLITIKTDVLALTVDTLGGDVVDAKLLKYNNTLGSKDPFVLLENNPEHSYVAQSGLIGQNGIDTNAGRAQFTVSGKDFTLAPDQKELRVPMTYEKDGIKYTKTFVLKPNSYAVNVDYTIDNQSAAPTSVQMYAQLRHSLVASKSSLTMPTYQGGAYSSVDTNYKKYSFDDMKDKNLNVTTPDGWVAVLQHYFVSAWIPRDGNESLNNLYSRSSDGNGYIGVRMPAVTVAPGATDTLKATLWVGPKLQNEMAATAKNLNLTVDYGWLWFIASPLHKLLSFIHSIVGNWGVAIMVLTFIVRGAMYPLTKAQYTSMAKMRMLQPKLQAMRERFGDDRQRLSQEMMELYRKEKVNPLGGCLPILVQMPIFIALYWALMESVELRHAPFFGWIHDLSAQDPYYILPILMGITMFMIQKMSPSTITDPMQQKIMTFMPVMFTFFFLWFPSGLVLYWLVSNIVTLIQQTLIYRSLEKKGLHSKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z166</accession>
    <name>D0Z166_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE</fullName>
            <ecNumber evidence="6">2.1.1.163</ecNumber>
            <ecNumber evidence="6">2.1.1.201</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">2-methoxy-6-polyprenyl-1,4-benzoquinol methylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Demethylmenaquinone methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ubiE</name>
        <name evidence="7" type="ORF">VDA_003280</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a 2-demethylmenaquinol + S-adenosyl-L-methionine = a menaquinol + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42640"/>
            <dbReference type="Rhea" id="RHEA-COMP:9539"/>
            <dbReference type="Rhea" id="RHEA-COMP:9563"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18151"/>
            <dbReference type="ChEBI" id="CHEBI:55437"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="EC" id="2.1.1.163"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a 2-methoxy-6-all-trans-polyprenyl-1,4-benzoquinol + S-adenosyl-L-methionine = a 6-methoxy-3-methyl-2-all-trans-polyprenyl-1,4-benzoquinol + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:28286"/>
            <dbReference type="Rhea" id="RHEA-COMP:10858"/>
            <dbReference type="Rhea" id="RHEA-COMP:10859"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:84166"/>
            <dbReference type="ChEBI" id="CHEBI:84167"/>
            <dbReference type="EC" id="2.1.1.201"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Quinol/quinone metabolism; menaquinone biosynthesis; menaquinol from 1,4-dihydroxy-2-naphthoate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.163" evidence="6"/>
    <dbReference type="EC" id="2.1.1.201" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302372.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003280"/>
    <dbReference type="EnsemblBacteria" id="EEZ42247">
        <property type="protein sequence ID" value="EEZ42247"/>
        <property type="gene ID" value="VDA_003280"/>
    </dbReference>
    <dbReference type="GeneID" id="57340287"/>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1431378at2"/>
    <dbReference type="UniPathway" id="UPA00079">
        <property type="reaction ID" value="UER00169"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043333">
        <property type="term" value="F:2-octaprenyl-6-methoxy-1,4-benzoquinone methylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043770">
        <property type="term" value="F:demethylmenaquinone methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102094">
        <property type="term" value="F:S-adenosylmethionine:2-demethylmenaquinol methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102955">
        <property type="term" value="F:S-adenosylmethionine:2-demethylmenaquinol-7 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102027">
        <property type="term" value="F:S-adenosylmethionine:2-demethylquinol-8 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009060">
        <property type="term" value="P:aerobic respiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009234">
        <property type="term" value="P:menaquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01813">
        <property type="entry name" value="MenG_UbiE_methyltr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004033">
        <property type="entry name" value="UbiE/COQ5_MeTrFase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023576">
        <property type="entry name" value="UbiE/COQ5_MeTrFase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01209">
        <property type="entry name" value="Ubie_methyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01934">
        <property type="entry name" value="MenG_MenH_UbiE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51608">
        <property type="entry name" value="SAM_MT_UBIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01183">
        <property type="entry name" value="UBIE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01184">
        <property type="entry name" value="UBIE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0474">Menaquinone biosynthesis</keyword>
    <keyword evidence="2 6 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 6 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0830">Ubiquinone</keyword>
    <keyword evidence="4 6" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="6">
        <location>
            <begin position="123"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ42247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="251" mass="28136" checksum="41BCC5FCA3C72ECF" modified="2010-01-19" version="1">MTDTTQETTHFGFRTVAKDDKAAMVAEVFHSVAAKYDMMNDVMSFGIHRAWKRFTIDCSGARRGQRILDLGGGTGDLTAKFSRIVGEDGQVILADINNSMLKVGRSKLRDIGVVGNVGYVQANAEELPFPDNYFDCITISFCLRNVTDKDKALRSMFRVLKPGGRLLVLEFSKPIVEPLSKIYDAYSFHILPKMGELVANDSESYRYLAESIRMHPDQETLKGMMEDAGFEQTTYYNLTGGIVALHRGYKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z184</accession>
    <name>D0Z184_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Multidrug efflux pump component MtrF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003298</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302430.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ42265">
        <property type="protein sequence ID" value="EEZ42265"/>
        <property type="gene ID" value="VDA_003298"/>
    </dbReference>
    <dbReference type="GeneID" id="57340266"/>
    <dbReference type="eggNOG" id="COG2978">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="350103at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015558">
        <property type="term" value="F:secondary active p-aminobenzoyl-glutamate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902604">
        <property type="term" value="P:p-aminobenzoyl-glutamate transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004697">
        <property type="entry name" value="AbgT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30282">
        <property type="entry name" value="PTHR30282"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03806">
        <property type="entry name" value="ABG_transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="182"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="229"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="282"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="321"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="364"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="403"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="430"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="460"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="486"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="510"/>
            <end position="531"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="533" mass="56714" checksum="BB2736A7753BA014" modified="2010-01-19" version="1">MYPSTSQQQSPQPSKKNLFTRFLDTVEWLGNLLPHPITLFAIFCVAILLASGIAGYFGLSVIDPRPEGAPGRAADGMIHVVSLLNAEGLQLIVANLVKNFTGFAPLGTVLVAMLGVAIAEHSGLLSSAMRGLVMGASRRMVTLVVVFAGIISNTASELGYVVLIPLAAMLFHSLGRHPLAGLAAAFAGVSGGYSANLLLGTVDPLLSGITQTAAQMIDPNYLVGPEVNWYFMFASTFAITIMGAFVTEKIVEPKLGKYHDEEASEDLSHDKMGKLTDIEKKGLKMAGLAALVVAALLALTIVPSDGVLRNPTTGLVAGSPFLKGIVAFIFVFFAIPGFVYGKVVGTMNNDRDVINAMAKSMSSMGMYIVLVFFAAQFVAFFKWTNFGQVFAVGGADFLQSIGLTGPALFFAFILMCGFINLMIGSASAQWAVTAPIFIPMLMLVGYAPETIQAAYRIGDSVTNIITPMMSYFGMILAVATRYQKNLGLGTLISTMLPYSIVFVIGWSIMFYVWVFVLGIPVGPGAATYYNVAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1D4</accession>
    <name>D0Z1D4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative nucleotide sugar epimerase</fullName>
            <ecNumber evidence="2">5.1.3.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003348</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="5.1.3.12" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302545.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003348"/>
    <dbReference type="EnsemblBacteria" id="EEZ42315">
        <property type="protein sequence ID" value="EEZ42315"/>
        <property type="gene ID" value="VDA_003348"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0451">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1180629at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="334" mass="37454" checksum="A3F08F7AE4FBA849" modified="2010-01-19" version="1">MKYLVTGAAGFIGSAVTERLCALGHQVVGVDNLNDYYDVSLKQARLQRAANPLFTFIELDLADREGVAQLFADQQFDKVIHLAAQAGVRYSIDNPLAYADSNLVGHLTILEGCRHHKVKHLVYASSSSVYGLNHKTPFNTSDSVDHPISLYAATKKSNELMAHTYSHLYGVPTTGLRFFTVYGPWGRPDMALFKFTNAIMEGKEIDVYNHGDMRRDFTYIDDIVEGVMRIQDVIPEPNPDWTVETGSPATSSAPYRVYNIGHGSPVKLMDYIEALEEALGIEAKKNFMDMQPGDVYMTYADTEDLFNATGYKPEVKVKEGVKAFVDWYRAYYQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1J2</accession>
    <name>D0Z1J2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type IV pilus biogenesis protein PilO</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003406</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302656.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003406"/>
    <dbReference type="EnsemblBacteria" id="EEZ42373">
        <property type="protein sequence ID" value="EEZ42373"/>
        <property type="gene ID" value="VDA_003406"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3167">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1803493at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043683">
        <property type="term" value="P:type IV pilus assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043107">
        <property type="term" value="P:type IV pilus-dependent motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007445">
        <property type="entry name" value="PilO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014717">
        <property type="entry name" value="Transl_elong_EF1B/ribosomal_S6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04350">
        <property type="entry name" value="PilO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016482">
        <property type="entry name" value="PilO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="17"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="196" mass="22670" checksum="98FB70C9536D11FB" modified="2010-01-19" version="1">MKEWQDLELDEMADWPLLPQCLVALLLAGLLIAVGYWYWLTPKSEQLAQIKQQEVELKMRLTNRASQVAALPIMKEQIEELNRRYDKVMKQLPVEKELATLLAGINDIGVRSGLEFQSIEWAPIREQEWYYELPINMQLTGSYKQMGHFAASVARLSRIVNLKDIDLKMIEQKGLQETLAMKVSASTYRFKAPKTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1J4</accession>
    <name>D0Z1J4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Shikimate kinase</fullName>
            <shortName evidence="10">SK</shortName>
            <ecNumber evidence="3 10">2.7.1.71</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">aroK</name>
        <name evidence="11" type="ORF">VDA_003408</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>ATP + shikimate = 3-phosphoshikimate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13121"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.71"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="10">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 5/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the shikimate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.71" evidence="3 10"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003408"/>
    <dbReference type="EnsemblBacteria" id="EEZ42375">
        <property type="protein sequence ID" value="EEZ42375"/>
        <property type="gene ID" value="VDA_003408"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0703">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00088"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004765">
        <property type="term" value="F:shikimate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00464">
        <property type="entry name" value="SK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00109">
        <property type="entry name" value="Shikimate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031322">
        <property type="entry name" value="Shikimate/glucono_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000623">
        <property type="entry name" value="Shikimate_kinase/TSH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023000">
        <property type="entry name" value="Shikimate_kinase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01202">
        <property type="entry name" value="SKI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01128">
        <property type="entry name" value="SHIKIMATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9 10" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="8 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 10 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10 11" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="10">
        <location>
            <position position="7"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ42375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="143" mass="16367" checksum="13517995F119E723" modified="2010-01-19" version="1">MEFFDSDTEIEERTGADISWVFDVEGEEGFRVREEKVIDDLTQEQGIVLATGGGSVMSKENRNRLSARGVVVYLETTIEKQLARTQRDKKRPLLQTDTPREVLEALAEERNPLYTEVSDYVVRTDDQSAKVVANQIIKMLEER</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1T4</accession>
    <name>D0Z1T4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MSHA biogenesis protein MshG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_003498</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GSP F family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303613.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003498"/>
    <dbReference type="EnsemblBacteria" id="EEZ42465">
        <property type="protein sequence ID" value="EEZ42465"/>
        <property type="gene ID" value="VDA_003498"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1459">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1268170at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.81.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003004">
        <property type="entry name" value="GspF/PilC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018076">
        <property type="entry name" value="T2SS_GspF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042094">
        <property type="entry name" value="T2SS_GspF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30012">
        <property type="entry name" value="PTHR30012"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00482">
        <property type="entry name" value="T2SSF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00812">
        <property type="entry name" value="BCTERIALGSPF"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="171"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="211"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="375"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="8">
        <location>
            <begin position="69"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="8">
        <location>
            <begin position="272"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ42465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="405" mass="44819" checksum="23A0607E9B31031C" modified="2010-01-19" version="1">MAMFQYKGRYQGAIRQGKIEAASSDAAADLLLQQGIIPLDLKPYSESPLNFDLMALFKAPLPLEILVIFCRQLYSLTKAGIPLLRAIKGLAQSTSHPLLRETLEAVIADLTNGSPLSVSMKQHPRVFTPLFVSMINVGENTGRLDSSLLQLANYYEQEMETRRQIASAMRYPMFVLTSIGLAMVVLNIKVIPQFASMFSRFGMELPLPTRILIGTSNFFVHYWPLLLGASLATWIGLRVWRNTVKGQETWDNWRLKVPVTGSIVTRAQMARFSRTFALMIRAGVPLNTALQMSAEALGNRYLENRLIEMKSGIEGGASIASTAVSSGIFPPLVLQMIAVGEETGQVDDLLMEVADFYDREVDYDLKTLTARIEPILLLVVAGMVLLLALGIFLPMWGMLDLARGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1W9</accession>
    <name>D0Z1W9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5 7">30S ribosomal protein S9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpsI</name>
        <name evidence="8" type="ORF">VDA_003533</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uS9 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303719.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003533"/>
    <dbReference type="EnsemblBacteria" id="EEZ42500">
        <property type="protein sequence ID" value="EEZ42500"/>
        <property type="gene ID" value="VDA_003533"/>
    </dbReference>
    <dbReference type="GeneID" id="57339990"/>
    <dbReference type="eggNOG" id="COG0103">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1766414at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00532_B">
        <property type="entry name" value="Ribosomal_S9_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000754">
        <property type="entry name" value="Ribosomal_S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023035">
        <property type="entry name" value="Ribosomal_S9_bac/plastid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020574">
        <property type="entry name" value="Ribosomal_S9_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21569">
        <property type="entry name" value="PTHR21569"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00380">
        <property type="entry name" value="Ribosomal_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00360">
        <property type="entry name" value="RIBOSOMAL_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ42500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="130" mass="14797" checksum="C81F874BC1061C84" modified="2010-01-19" version="1">MAENQYYGTGRRKSSAARVFIKPGTGNIVINKRSIEEYFGRPTARMVVRQPLELVEMTEKLDLYITVKGGGITGQSGAIRHGITRALMEYDETLRPALRAAGYVTRDARRVERKKVGLRKARRRPQFSKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z230</accession>
    <name>D0Z230_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001879</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298864.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40847">
        <property type="protein sequence ID" value="EEZ40847"/>
        <property type="gene ID" value="VDA_001879"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031208">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1594393at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="182" mass="21335" checksum="08A43AAB6E64CB4C" modified="2010-01-19" version="1">MAVFFRLLLTFSSLLLSFSVYLVASDYKIKIFSYTFNFLQSISTYFFIVIVFSVITLFIARFIHDLDFPVDSFESIEIANDSFLPSYLGYFFVALSAASYDKPINLHSFLYVFFIMAIFIYCSRISFFNPIFLLFGYNFFYVTTKNGVKIILITKKTIKDPLRFTSGKVKKINEYTYLDMEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z268</accession>
    <name>D0Z268_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_001915</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DcuC/DcuD transporter (TC 2.A.61) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298928.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001915"/>
    <dbReference type="EnsemblBacteria" id="EEZ40883">
        <property type="protein sequence ID" value="EEZ40883"/>
        <property type="gene ID" value="VDA_001915"/>
    </dbReference>
    <dbReference type="GeneID" id="57341959"/>
    <dbReference type="eggNOG" id="COG3069">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1345750at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015556">
        <property type="term" value="F:C4-dicarboxylate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004669">
        <property type="entry name" value="C4_dicarb_anaerob_car"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018385">
        <property type="entry name" value="C4_dicarb_anaerob_car-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42002">
        <property type="entry name" value="PTHR42002"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03606">
        <property type="entry name" value="DcuC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00771">
        <property type="entry name" value="DcuC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="98"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="128"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="192"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="243"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="270"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="309"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="344"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="371"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="406"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="431"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ40883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="451" mass="47826" checksum="EDD4B63E82991CC9" modified="2010-01-19" version="1">MITVFSLIVIFLVGTLIYKKFNPQTTLFIGGIVMMSAAIIFNIGTPLPEGASSGNSWLDIFTFIKNTTAKTVGSLGLIIMAVGGFAKYMDHIGASRALVNIAIKPLGYFKAPYFVMALGYIMGQILNVFIPSASGLGLLLMVTLYPILVRLGVSKMSAVAVIATSACLDLGPASGNVNLAAKTADMPVTEYFVNYQMPVAIATMITIAVLHFFVQQWFDKKGLVQAENNDIQVEDELANPPSWYAFLPIIPLGLIMILSPLAIESVKIDVVTAMFISIAVAMICEGFRQGAKAVFNDIIVYFDSMGRQFARVVTLVIAGQVFAHGMKVIGLLDTVIDAAVHASLSPAIMIILMVVIITFAAILMGSGNAPFFSFAAMVPEIAGKVGINSIIMLMPMQLASGIARSMSPITGAIVAVAGVAEVSPFELVKRTAIPMIGALIVSTAVSLIIGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z284</accession>
    <name>D0Z284_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HNHc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001928</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298955.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001928"/>
    <dbReference type="EnsemblBacteria" id="EEZ40896">
        <property type="protein sequence ID" value="EEZ40896"/>
        <property type="gene ID" value="VDA_001928"/>
    </dbReference>
    <dbReference type="GeneID" id="57341944"/>
    <dbReference type="eggNOG" id="COG1403">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1843957at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00085">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002711">
        <property type="entry name" value="HNH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01844">
        <property type="entry name" value="HNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00507">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNHc" evidence="1">
        <location>
            <begin position="19"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="118" mass="13476" checksum="9925F35294F4D97B" modified="2010-01-19" version="1">MSSDVTGSSAKYKRLEAGYREKALKIYPWVCGRCSREFVYSNLRELTVHHVDHDHTNNPEDGSNWELLCLFCHDHEHEKYTEADNGMGSVIKAGEDDHQAATFNPFADLKAMMAKNKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z285</accession>
    <name>D0Z285_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0234 protein VDA_001934</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001934</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0234 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298964.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40902">
        <property type="protein sequence ID" value="EEZ40902"/>
        <property type="gene ID" value="VDA_001934"/>
    </dbReference>
    <dbReference type="GeneID" id="57341938"/>
    <dbReference type="eggNOG" id="COG1666">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1612988at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11740">
        <property type="entry name" value="YajQ_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.860">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00632">
        <property type="entry name" value="UPF0234"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007551">
        <property type="entry name" value="DUF520"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035571">
        <property type="entry name" value="UPF0234-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035570">
        <property type="entry name" value="UPF0234_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036183">
        <property type="entry name" value="YajQ-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30476">
        <property type="entry name" value="PTHR30476"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04461">
        <property type="entry name" value="DUF520"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89963">
        <property type="entry name" value="SSF89963"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="160" mass="18091" checksum="C1C0951C4A554093" modified="2010-01-19" version="1">MPSFDIISEVDNVEIKNAVDNSIRELDTRFDFRGVESSIELNKETVKIKSESEFQIDQIVAILRNNLAKRGVDANSLERKTVNFSGKTASQDIEFKQGIDQATAKKLVKAVKDSKIKVQVSIQGDKLRVTGKKRDDLQATMALVREQDLGQPFQFDNFRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2C4</accession>
    <name>D0Z2C4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000575</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000575"/>
    <dbReference type="EnsemblBacteria" id="EEZ39555">
        <property type="protein sequence ID" value="EEZ39555"/>
        <property type="gene ID" value="VDA_000575"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2856">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1938768at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025644">
        <property type="entry name" value="DUF4344"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14247">
        <property type="entry name" value="DUF4344"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018838" evidence="1">
        <location>
            <begin position="23"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="256" mass="29173" checksum="9FC9643ECB4614A8" modified="2010-01-19" version="1">MFKKLCFASALICTTLSGTTSAAGGIEYTFQSPNTQSQKSAYDEIKASRVNQLVGKLSNEHFPFTQTLTIHYGGEDGPLYDPDLHTIFIPYAFYTQAIHYFAQNRYQKMYGKSAKEAAVDTILHTLLHEVGHAYIDDNGIPILGKEEDAVDNFAAIVLINYVKKGADITISAADMFAFESDDKPDYYDSSEYIDEHSFDLQRYFSTLCLVYGAEPKQYPNLLDEINKLDVKDRQTFCIEHYQTISENWQKYFKTEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2Q1</accession>
    <name>D0Z2Q1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000702</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000702"/>
    <dbReference type="EnsemblBacteria" id="EEZ39682">
        <property type="protein sequence ID" value="EEZ39682"/>
        <property type="gene ID" value="VDA_000702"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3656">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014469">
        <property type="entry name" value="DUF2271"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10029">
        <property type="entry name" value="DUF2271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF014995">
        <property type="entry name" value="UCP014995"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003020015" evidence="1">
        <location>
            <begin position="23"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="172" mass="19826" checksum="43C62B0B8EF66A02" modified="2010-01-19" version="1">MKTLTQFFGASLLLCGSMSLSASPLPAQAKLAVEFELPSIETSMYARPYVAVWIENDQRQPVRTMQLWVGKDEWLKDLRSWWRKVGRNDRELVDAVTSATRPAGQYRFSWDGLDDKGQRLDQGEYTFYVEVVREHGGRNYLRQKVTLADQEQKYQLAPTQETGSISLHYTTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2Z3</accession>
    <name>D0Z2Z3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Ferrichrome-iron receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">VDA_000794</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305370.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000794"/>
    <dbReference type="EnsemblBacteria" id="EEZ39774">
        <property type="protein sequence ID" value="EEZ39774"/>
        <property type="gene ID" value="VDA_000794"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4773">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="169533at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015344">
        <property type="term" value="F:siderophore uptake transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038023">
        <property type="term" value="F:signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039423">
        <property type="entry name" value="TonB-dep_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010105">
        <property type="entry name" value="TonB_sidphr_rcpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32552">
        <property type="entry name" value="PTHR32552"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01783">
        <property type="entry name" value="TonB-siderophor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 13" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="5 9" id="KW-0798">TonB box</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003020030" evidence="10">
        <location>
            <begin position="23"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="12">
        <location>
            <begin position="55"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="11">
        <location>
            <begin position="233"/>
            <end position="690"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ39774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="691" mass="76497" checksum="A37C042AC785A7CC" modified="2010-01-19" version="1">MFSKSQLALLIGATLAAPVSFAQNVEADEHMVVTGRDYGYKADTNSTAMRMEMTQLETPGQVAVIDEKLIDEQRASTLGEVLQNDASISAGGTSRNRERFSLRGFELGSSSGFLRDGHQHWSHYRQPIELLERVEVMKGPAGLLYGKSAPGGLVNMVSKKPTHETQVNFSQDVGSNNHTRTVADVSGSLNADQSLRGRVVLAKEDYDSWRRYGDGTKPSTDRFVGGLFLDYDINDDVTVSVHYDRTEDKGSVDSGAYVVDGKVVRGDKYIWDAQWSTIDNTVQNTGIDVKAQLTDSWALNTGFNHQDFKRVDVESYPSFNDYASTGKIVHSGNDRHDHWVFNTAYSDLVGELDFLGTQHQVLIGANWLGYSYDRAQYYFDKVTTEPGQTVPKPGYSGKTRKSNSEYDAWGFYLQDMMTINDYWQFLAGVRFDRQTQEGKAAEEAISPKVAAIFHPADNGSIYLSYSESFEPQGVVSSDYVNAGDKLDPLRGKQYELGTKWELLDSRLYVSGAVFNITQENSKIAVGPKDNQTLTQGGERVHNGAELALQGKVTDKLNVNASAMYLDAEYTKDQNFEGNRPADVPEFAASVWSTYNVTDATDVNLGVIYEGSRYGDAANTFKKPGYTRVDMGVSHTYKYDEKLDIIGRLNVENVFDTDYLAGGGSTSSKYPGATGVTIGEGRNFMATVEFKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z353</accession>
    <name>D0Z353_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pyruvate dehydrogenase [ubiquinone]</fullName>
            <ecNumber evidence="2">1.2.5.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Pyruvate oxidase</fullName>
            <shortName evidence="2">POX</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Pyruvate:ubiquinone-8 oxidoreductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">poxB</name>
        <name evidence="7" type="ORF">VDA_000854</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">A peripheral cell membrane enzyme that catalyzes the oxidative decarboxylation of pyruvate to form acetate and CO(2). It channels electrons from the cytoplasm to the respiratory chain at the cell membrane via ubiquinone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a ubiquinone + H2O + pyruvate = a ubiquinol + acetate + CO2</text>
            <dbReference type="Rhea" id="RHEA:27405"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="EC" id="1.2.5.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="2">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="2">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
        <text evidence="2">Binds 1 thiamine pyrophosphate per subunit.</text>
    </comment>
    <comment type="activity regulation">
        <text evidence="2">The C-terminus inhibits activity; it has to move for the enzyme to be active. Activated by lipid-binding, which occurs via the C-terminus.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="2">Has 4 domains; the Pyr domain which binds the pyrimidine moiety of the thiamine pyrophosphate cofactor, the FAD-binding domain, the PP-binding domain which binds the pyrophosphate portion of thiamine pyrophosphate and the C-terminal membrane binding region. The C-terminus is held closely against the rest of the protein and covers the active site; during activation it unfolds from the rest of the protein and forms an amphipathic helix upon membrane binding, exposing the active site.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2 3">Belongs to the TPP enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.2.5.1" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305536.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000854"/>
    <dbReference type="EnsemblBacteria" id="EEZ39834">
        <property type="protein sequence ID" value="EEZ39834"/>
        <property type="gene ID" value="VDA_000854"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="351701at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052737">
        <property type="term" value="F:pyruvate dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048039">
        <property type="term" value="F:ubiquinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042867">
        <property type="term" value="P:pyruvate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00850">
        <property type="entry name" value="POX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044261">
        <property type="entry name" value="PoxB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012000">
        <property type="entry name" value="Thiamin_PyroP_enz_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012001">
        <property type="entry name" value="Thiamin_PyroP_enz_TPP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme-bd_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00205">
        <property type="entry name" value="TPP_enzyme_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02776">
        <property type="entry name" value="TPP_enzyme_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 7" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="2 7" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="TPP_enzyme_N" evidence="6">
        <location>
            <begin position="1"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_M" evidence="4">
        <location>
            <begin position="190"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_C" evidence="5">
        <location>
            <begin position="379"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="FAD-binding domain" evidence="2">
        <location>
            <begin position="181"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Thiamine pyrophosphate binding" evidence="2">
        <location>
            <begin position="406"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Thiamine pyrophosphate binding" evidence="2">
        <location>
            <begin position="433"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Thiamine pyrophosphate binding" evidence="2">
        <location>
            <begin position="460"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Membrane-binding domain" evidence="2">
        <location>
            <begin position="531"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="249"/>
            <end position="252"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="272"/>
            <end position="276"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="290"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="433"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="460"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="site" description="Moves into active site upon enzyme activation, plays a role in electron transfer" evidence="2">
        <location>
            <position position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="572" mass="62156" checksum="6DD39077B6E276CD" modified="2010-01-19" version="1">MKIAQYMVKLLSEAGVKRIWGVTGDSLNGISDSLRADGTIEWIGTRHEEVAAFAAGAEAELTGELAVCAGSCGPGNMHLINGLYNCYRNKVPVLAIASDIPSSEIGTHYFQETDPTRLFKECSVFCEKLTTPEQMPQLMETAMRQAILKRGVSVIVVPGDVALLDMPKNTAIKWQRPTLPLTMPIISDLNQCAEILNQSVKTVLFCGAGTKDSHKQVIELAEKLKAPIVHALRGKEHIEYDNPFDVGMTGLIGFSSGYHAMENADVVILVGTSFPFRPFYPKGAKIVQIDNDSSAIGRHTQIDLGIVADVQPTLSALLPLLDENHNTEFLNKCVEHYQKTRKELDNLAEVKPKSALIHPQTLSKVISEKAHQDAVFTCDVGTPTLWAARYLKMNGHRRLLGSFNHGSMANAMAQAIGAQAVDKDRQVIAMCGDGGFSMLMGDLLTLAPYQLPVKIVILNNSALGFVDMEMKAAGFVSNATDLHNPSFAAIANACGIKGIKVSGPKKLNEAVDELLAHQGPALLEVITDKHELSMPPKIQLAQEKGFAIYMLKALFNGYGDELVEVAKTNLLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z355</accession>
    <name>D0Z355_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Paraquat-inducible protein B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000856</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000856"/>
    <dbReference type="EnsemblBacteria" id="EEZ39836">
        <property type="protein sequence ID" value="EEZ39836"/>
        <property type="gene ID" value="VDA_000856"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1463">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3008">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003399">
        <property type="entry name" value="Mce/MlaD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02470">
        <property type="entry name" value="MlaD"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MlaD" evidence="1">
        <location>
            <begin position="2"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="MlaD" evidence="1">
        <location>
            <begin position="110"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="MlaD" evidence="1">
        <location>
            <begin position="239"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="498" mass="54818" checksum="6B6D05EC78FA5CF3" modified="2010-01-19" version="1">MPTAEGIEVGKTQIKSLNVKVGVVTNIQLSDDYSYITVTARMNKDAERMLRDDTLFWVVKPRIGKEGISGLDTLLSGSYIELQPGKSDIKKHNFKVLDVPPIAPPDAKGLRVVLTNKEAGKLSVGDPVLYEGFTVGRVEQVSFNTNTKLANYHLFIFQPYDSLIQTTTKFWLASGVDFQMSASGINVKIGSLESLITGGVSFGLPDGVSSGEKVTTQNEKYRLYDNMKQVTEGMYDQYLPYVMLFKESIRGLQPGAPVEYRGVRIGTVEKVPFKLPTNKHGFSNKMIPILVHIELGRITQLGGHETLEGLKADLQKEFKTGLRATLKTGSLITGALFIDLNVDPDEKAPKLQSFDGYDIFPTKAGGFAEVQKQVTDLLKKLNNLPVEKTVNSLNSTLAATEKTLQSAERVTADLDRLLKQKDTQQLPADIRQSLKEIQHTLNSYGPNGAPYQNLEGALNQFQDVMQELQPVLKQINKKPNSLIFGGDKTADPIPAGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z374</accession>
    <name>D0Z374_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Serine-type D-Ala-D-Ala carboxypeptidase</fullName>
            <ecNumber evidence="4">3.4.16.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">VDA_000875</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the peptidase S11 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.4" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305598.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000875"/>
    <dbReference type="EnsemblBacteria" id="EEZ39855">
        <property type="protein sequence ID" value="EEZ39855"/>
        <property type="gene ID" value="VDA_000875"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1686">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1499212at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009002">
        <property type="term" value="F:serine-type D-Ala-D-Ala carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015956">
        <property type="entry name" value="Peniciliin-bd_prot_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018044">
        <property type="entry name" value="Peptidase_S11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012907">
        <property type="entry name" value="Peptidase_S11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037167">
        <property type="entry name" value="Peptidase_S11_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001967">
        <property type="entry name" value="Peptidase_S11_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07943">
        <property type="entry name" value="PBP5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00768">
        <property type="entry name" value="Peptidase_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00725">
        <property type="entry name" value="DADACBPTASE1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00936">
        <property type="entry name" value="PBP5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69189">
        <property type="entry name" value="SSF69189"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 17" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="9" id="KW-0133">Cell shape</keyword>
    <keyword evidence="11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="8 17" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="15" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="domain" description="PBP5_C" evidence="16">
        <location>
            <begin position="281"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="12">
        <location>
            <position position="65"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="12">
        <location>
            <position position="68"/>
        </location>
    </feature>
    <feature type="active site" evidence="12">
        <location>
            <position position="128"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR618044-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR618044-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU004016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EEZ39855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="414" mass="46345" checksum="CA8E13A95B27E245" modified="2010-01-19" version="1">MLKTLNLYVYRLIFASCLVIPSFYSHSAYLLDPPDIDAKAWVLMSYNTGQIIAGDNLHKPLAPASLTKIMTTFVVGEEIKAGNIQLSDMVTISENAWGKKFPGSSKMFLNVGDSVSVEDLLRGVIVSSGNDATVALAEHVAGHQSAFIKMMNQYAERYGMKDSYFSNPHGLDADDQTTSAYDMALLTRAFIQEVPDIYDMHKEKSFTFGDIKQGNRNALLWDETLHVDGVKTGYTKQAGYSLVSSAKNGEQRLIAVVLGTKSAKARRLESKQLLSWGFRFYEDITPQLDDKLLEPIRIWHGEPASAELTLGDAGMITVPSRLKNKLKPIITYRENLAPPLEKGQQVGKIDWYINEQLLVSQPILTQGEILKAPWYNSAIDSLLQPIYTWLNKYGLTKQREQLQARDIVQPMSQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z376</accession>
    <name>D0Z376_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hypothetical nitroreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000877</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305604.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000877"/>
    <dbReference type="EnsemblBacteria" id="EEZ39857">
        <property type="protein sequence ID" value="EEZ39857"/>
        <property type="gene ID" value="VDA_000877"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0778">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1847197at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.109.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029479">
        <property type="entry name" value="Nitroreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000415">
        <property type="entry name" value="Nitroreductase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00881">
        <property type="entry name" value="Nitroreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55469">
        <property type="entry name" value="SSF55469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitroreductase" evidence="1">
        <location>
            <begin position="12"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="242" mass="27726" checksum="7E37E433FC8930EE" modified="2010-01-19" version="1">MTNHHDTFKELIESRRSVRKYDQTAHFDHQAVARSLELATLSPNSSNMQLWEFHRVVTPNLKEQIATFCMGQNAAKTASELVIVVTTPYKWRQRAQMNAQQIREAFTGREDATATRALKYYEKLIPFIYNNDRLGLFGTGRKLLSAIIGLKRPMVREVSKQDLRTCLHKSSSLAAMTFMTAMRSEGYDTCPMEGFDSKRVKQILQLPKQAEITMIIGCGLRADDGIYGERHRVNHSDVIFEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3F6</accession>
    <name>D0Z3F6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000957</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305830.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39937">
        <property type="protein sequence ID" value="EEZ39937"/>
        <property type="gene ID" value="VDA_000957"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031N63">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1730492at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="114" mass="12572" checksum="8DCF893137727563" modified="2010-01-19" version="1">MKISVDGGSFKVAIKTEYEGLVGEATAIFHETLKQAKSNDKAILRFLQIIIEHRDEDDAIGYAVLGLLGWYNEAINPVTNHDIELNLPKIIPHLINPSGDLTATSATETNTFKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3L0</accession>
    <name>D0Z3L0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative DNA-binding response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_001011</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305982.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001011"/>
    <dbReference type="EnsemblBacteria" id="EEZ39991">
        <property type="protein sequence ID" value="EEZ39991"/>
        <property type="gene ID" value="VDA_001011"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="817710at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="6"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="134"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="134"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ39991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="241" mass="27196" checksum="2135FDB63F0A460D" modified="2010-01-19" version="1">MSQGKKVLVVDDDQEIRELLDEYLTKSGFHVVTAAEGEEMKRKLAAGEPDLILLDVMMPGDDGFTLCQHIRKTSDVPIIMLTAVSDEMDQIIGLELGADDYIAKPFSPRQLMARIKALLRRVKPTETQQAPATPKFIRFANWRLDTSTHILYNLEKGHEHELTGGDYALLMLFLSRPNEILDRDTISYATRGREVQASERGVDVALSRLRQRLGDKGRTQRLIKTSRGNGYIFTADVSYES</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3P5</accession>
    <name>D0Z3P5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001046</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306073.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001046"/>
    <dbReference type="EnsemblBacteria" id="EEZ40026">
        <property type="protein sequence ID" value="EEZ40026"/>
        <property type="gene ID" value="VDA_001046"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0561">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1374424at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000150">
        <property type="entry name" value="Cof"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006379">
        <property type="entry name" value="HAD-SF_hydro_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00099">
        <property type="entry name" value="Cof-subfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01484">
        <property type="entry name" value="HAD-SF-IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="270" mass="29693" checksum="E7EAA34459ACF3AD" modified="2010-01-19" version="1">MYKLVALDMDGTLLNSEHKITERNKQAISAARAKGVHVVLASGRPLEGMQTALQELNMTSDDDFVLSYNASLVQRIASQAVVRSNILTGADAKRIARKAKELGVHVHAFSRTEGLITPEHNYYTDHEAKINELSITLKDFETLEDDEEIMKVMIIDVPEKLSAAHEQLPEAFFKDYTIVKSAPFFLEFMNPNSNKGTGVKALADYLGIDASEVICMGDAGNDHHMIKYAGLGVAMENASEDTKAIANYITDTNDNSGVAQVIEKFILNAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3S8</accession>
    <name>D0Z3S8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">PTS system N-acetylgalactosamine-specific IIC component</fullName>
            <ecNumber evidence="8">2.7.1.69</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_001079</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.7.1.69" evidence="8"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306168.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001079"/>
    <dbReference type="EnsemblBacteria" id="EEZ40059">
        <property type="protein sequence ID" value="EEZ40059"/>
        <property type="gene ID" value="VDA_001079"/>
    </dbReference>
    <dbReference type="GeneID" id="57343452"/>
    <dbReference type="eggNOG" id="COG3715">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1687744at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103111">
        <property type="term" value="F:D-glucosamine PTS permease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008982">
        <property type="term" value="F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004700">
        <property type="entry name" value="PTS_IIC_man"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03609">
        <property type="entry name" value="EII-Sor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51106">
        <property type="entry name" value="PTS_EIIC_TYPE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="136"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="178"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="218"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ40059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="254" mass="26892" checksum="F2EB402AF0F0F6FA" modified="2010-01-19" version="1">MFFEAALVAVWAFFCGIDKYDVALNIHRPLITGPVVGLIMGDLQIGLIAGATLELAWLGLVPNAGAQPPDVTMGTIAAVAFAVMTGQSPAVAMGVGMPIAVMMQMLVIGFFAMTAFTMGKADRFAEQGDSDGIDRLLITTISLRAVLYAVIAFITVYFGEHAATWIDENAPKALLEGLGIGAKMVPAIGFAMLLKIMWSKEVAGVFFIGFVMTTYLKLPIMAVAILGASAAALYFFFSGNGNSNKQAEEFEDGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3U2</accession>
    <name>D0Z3U2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_001093</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306205.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001093"/>
    <dbReference type="EnsemblBacteria" id="EEZ40073">
        <property type="protein sequence ID" value="EEZ40073"/>
        <property type="gene ID" value="VDA_001093"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG503412Z">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1482355at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ40073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="372" mass="41501" checksum="01931F3A879C856B" modified="2010-01-19" version="1">MMNHFLRKTIYNIFFVVVLISSFSGYSMTINGTIKDGAMRWNNAIRVDGFLSMSNWQIISGLQPTEEWKPGGLMSVTGIKDSNLILSNGSKEITIPFDISGVQYGLGDSGGKFDIVSSGSASFSACDTRSISSAKASIIGKKCASKESYKGKNGLQFTPFHFARPLISLKDSDIIDQFNDPSLTKGIYKGTVNIIPMYVFKSPTGTWTYRTTTPIAIDIAIKYSGSQMFNVEVIGDGIITPRYNREQKTVTGFTDFQVKFNGVFPKGTRINMRFLEPEAGIYNLKATDSSISEDKNKIPYGIYCHGKSCHDKEIVDYHGQMILDDKKSYLESTDDSKEISFRFLVGYKDIPMNKVDTGKYQDSFTVMFESEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3W5</accession>
    <name>D0Z3W5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidase_M14 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001118</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306269.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001118"/>
    <dbReference type="EnsemblBacteria" id="EEZ40096">
        <property type="protein sequence ID" value="EEZ40096"/>
        <property type="gene ID" value="VDA_001118"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3608">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="397741at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000834">
        <property type="entry name" value="Peptidase_M14"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00246">
        <property type="entry name" value="Peptidase_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M14" evidence="1">
        <location>
            <begin position="75"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="307" mass="34138" checksum="07487B488CB4F573" modified="2010-01-19" version="1">MEQSSAYPIGVHGQKWGEAEVAAWRAQTSIKRSYLDEVVSKIAILEEDFDVEPYGELTYIPGQYPLFVIRSRNFDSNKPTVLITGGVHGYETSGVHGALEFLATQAFNYEPHFNFIVIPCVSPWGYETINRWNPNAIDPNRSFFTNTPAEESAWVMDVVNKCEYPILVHIDLHETTDTDESEFRPALAARDGKDYIEDSVPDGFYVVGDSENPQDSFQKAIIDSVRHVTHIAPPDQDGNIIGEPITQEGVINYPLKALSLCASITGALYTTTTEVYPDSPKVTDEECNQAQVAAITGALDYVLNQHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z406</accession>
    <name>D0Z406_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phosphoenolpyruvate--protein phosphotransferase</fullName>
            <ecNumber evidence="5">2.7.3.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">VDA_001159</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-histidyl-[protein] + phosphoenolpyruvate = N(pros)-phospho-L-histidyl-[protein] + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:23880"/>
            <dbReference type="Rhea" id="RHEA-COMP:9745"/>
            <dbReference type="Rhea" id="RHEA-COMP:9746"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:29979"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:64837"/>
            <dbReference type="EC" id="2.7.3.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PEP-utilizing enzyme family.</text>
    </comment>
    <dbReference type="EC" id="2.7.3.9" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306375.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001159"/>
    <dbReference type="EnsemblBacteria" id="EEZ40137">
        <property type="protein sequence ID" value="EEZ40137"/>
        <property type="gene ID" value="VDA_001159"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1080">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="467393at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008965">
        <property type="term" value="F:phosphoenolpyruvate-protein phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008982">
        <property type="term" value="F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00367">
        <property type="entry name" value="PTS-HPr_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00211">
        <property type="entry name" value="PTS_IIA_fru"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000032">
        <property type="entry name" value="HPr-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035895">
        <property type="entry name" value="HPr-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008279">
        <property type="entry name" value="PEP-util_enz_mobile_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000121">
        <property type="entry name" value="PEP_util_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023151">
        <property type="entry name" value="PEP_util_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036637">
        <property type="entry name" value="Phosphohistidine_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016152">
        <property type="entry name" value="PTrfase/Anion_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006318">
        <property type="entry name" value="PTS_EI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002178">
        <property type="entry name" value="PTS_EIIA_type-2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008731">
        <property type="entry name" value="PTS_EIN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001020">
        <property type="entry name" value="PTS_HPr_His_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004715">
        <property type="entry name" value="PTS_IIA_fruc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036618">
        <property type="entry name" value="PtsI_HPr-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05524">
        <property type="entry name" value="PEP-utilisers_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00391">
        <property type="entry name" value="PEP-utilizers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02896">
        <property type="entry name" value="PEP-utilizers_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00381">
        <property type="entry name" value="PTS-HPr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00359">
        <property type="entry name" value="PTS_EIIA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47831">
        <property type="entry name" value="SSF47831"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52009">
        <property type="entry name" value="SSF52009"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55594">
        <property type="entry name" value="SSF55594"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55804">
        <property type="entry name" value="SSF55804"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00848">
        <property type="entry name" value="fruA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01417">
        <property type="entry name" value="PTS_I_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00742">
        <property type="entry name" value="PEP_ENZYMES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51094">
        <property type="entry name" value="PTS_EIIA_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51350">
        <property type="entry name" value="PTS_HPR_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00369">
        <property type="entry name" value="PTS_HPR_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0598">Phosphotransferase system</keyword>
    <keyword evidence="13" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="13" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="HPr" evidence="12">
        <location>
            <begin position="5"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="PTS EIIA type-2" evidence="11">
        <location>
            <begin position="687"/>
            <end position="830"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ40137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="833" mass="92113" checksum="27B38F5FF7EFB2FE" modified="2010-01-19" version="1">MSHPIQSFQFQCPLPNGIHARPATHLEKQCQQFECQIILTNLRTQQSGDAKSVLSLVGTDTLLNDQCEMRFEGVDSEQACAALQHYIEQEFPHCDEALETLADESDIILPQSLTRLNPTLISGKRLATGIAQGQLSVFSQIEPEHFATEHKDEQEETRFTTAHQQVCHALSQKIANATAQEKEIIESHLAIVNDSAFVAGIKQHLANHSTANAILAEVERVSAQLRNASSSYLRERVLDIKDVAIQLLTAAYPEKNLITEFTLNKPSVVIANDLTPSQFLGLDREHLQGLVLTHAGSTSHTVILARAFGIPTLSGIELSDCTKALNQTVYLDANLGVLAVDATPQVAQYFHRAIKLAQTQQEKQNGFAQQKATTQDGHCIEVAANIACSIEAEGAFNQGAEGIGLFRTEMLFMDRSQAPDEEEQFNHYRQVLEAANGKPVIIRTMDIGGDKPIDYLQLPEEHNPFLGYRAVRIYPQFLTLFHTQLKAILRAAQYGKAKMMIPMIQSIEEIRWVKQQLEVVKAELSSQGVSYSEHLELGIMVEIPAVAFIVDQFCQEVDFFSIGSNDMTQYLLAVDRDNAQVAKLYNSLAPSFLRMLNQVVTTAHQHNKWVGLCGELGADAKVLPLLVGAGLDEISMGAPKIAATKSTLATLDFAHCQQLFADACQCCTISDVEQLLNQASSAQPGKALLSQDCVFKHADFSSKEEVIQALVGNLGVQGRCDNAYKLEEDVWAREAVFSTGLGHGFAIPHTKSENIRHSSISIAHLETPIDWQSDSGDVDFVIMLTLNKDQGDQHMRIFSSLARKLIHQSFRDMLRDADNEAEVIRILEQELAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z410</accession>
    <name>D0Z410_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative alpha-1,2-mannosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001163</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306382.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001163"/>
    <dbReference type="EnsemblBacteria" id="EEZ40141">
        <property type="protein sequence ID" value="EEZ40141"/>
        <property type="gene ID" value="VDA_001163"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3537">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="100818at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005887">
        <property type="entry name" value="Alpha_mannosidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041371">
        <property type="entry name" value="GH92_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012939">
        <property type="entry name" value="Glyco_hydro_92"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07971">
        <property type="entry name" value="Glyco_hydro_92"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17678">
        <property type="entry name" value="Glyco_hydro_92N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01180">
        <property type="entry name" value="aman2_put"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018826" evidence="1">
        <location>
            <begin position="18"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_92N" evidence="3">
        <location>
            <begin position="41"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_92" evidence="2">
        <location>
            <begin position="288"/>
            <end position="831"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="837" mass="94392" checksum="B1C71175E16A7DAB" modified="2010-01-19" version="1">MLIKRLPLALAISFALIGCNSDNNTVIDKTHPETEQSILDYVDPLIGTDGLGNVNPSPVTPEGMIQPSPDNWNPKNWNGKGSPSDYHHHLTMLSGFSTTHISGAGKGDLNDFAFLPYTKFNTKPVTMDKQSEVSEVGYYSVDLIETKIKAELTATDRVAFHRYTFPRNEDRKIQIDLQHELLEQYGNHSRSIYYKKISDHAIAGVRTSNEWGQWQTVYFYAEFSEPFTGHGVYVDGEPSSKNEVGLADYQGYGDKRERVRDIITHLNFAKGEQPITVKIAISGTGIDGAMANLKADNNGYDFASVVEQNKQKWANVLNKFSVEGGTEADKTLFYTSLYRTYIAPFVYQDVDGKYRGMDGKVHQAKEGFTNYSVYSMWDTFRAAHPLKTIIDKDRAIEYARDLLNKYQTGGVLPKWELHSDYTGEMVGYPAVSVIADIMVKHPEAFSQQEFQLALKAADVSANFDLELTHDWVPYRDPWNGDKRFTVMTRHGQYAEQHGYVPADVKKKPQDGGYAQDKYDELVNESVSYGVENAYYDWCIAQIAKLAGNEAQYQRYLERSLAYKPYFDFNPTEYGKYGATGFMRPKNYDGSWVNNYPSCAIDDGGNPISTLPEGCDINDATSFDIFWPYRAEHRGQDFTEGNTWQWTWFAPHDISGLKAVMGGEAGFLQNLDALFNANSEADTSQGDMTGYIGQFIMGNEPDHHVPYLYNWTAEPWKTQEYVTQAMRSFFHPTTDGLIGNEDVGQMSAWYIMSALGFYQVTPGLPSYTIGKPLFDKVVMDIDGGQFTITAENNSPENIYVESVTINGKPLDANLSFDHREIRPGGQLHFVMTDRPVKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z452</accession>
    <name>D0Z452_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nickel ABC transporter nickel-binding protein nikA2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000308</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304002.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000308"/>
    <dbReference type="EnsemblBacteria" id="EEZ39290">
        <property type="protein sequence ID" value="EEZ39290"/>
        <property type="gene ID" value="VDA_000308"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0747">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="162819at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030678">
        <property type="entry name" value="Peptide/Ni-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002741">
        <property type="entry name" value="MppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018900" evidence="1">
        <location>
            <begin position="23"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="domain" description="SBP_bac_5" evidence="2">
        <location>
            <begin position="66"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="524" mass="58718" checksum="3F3D56CF9441E5F7" modified="2010-01-19" version="1">MQKILTSCFLSLSLSVSISVHAQVPDTLYVALGDEPTAGFDPIMGWGKYGNPLFQSTLLKRNQQLEFVGDLAKVWTLSHDRKTWSVELRNDVKFSNGQPLAAKDVAFTFNQAKQALSSHDLTDLESITVLDPTHIEFHLTKPNITFLDHFSAIGIVPEKEYVTDTKEYTNGYGRHPVGSGPYILQSWQQGQFARLEKNPFYYGKQPQFEHLVLVFASEETRYGLLKTKQVQLAAIPQQFAKVLPVDYRLWQVPSVDNRGVVWPMNQPSKTEKGNRVSSSLAIREAVDMVIDKQLIVDTVMDGFARPAYSVADNMPWGLPAADRKQPLDNSFAIAAAQSLLDKAGWKVNANSGLREKEGVPAVMTLYYKAGDSVREQLALTVAQMVKPLGISMSVKGSDWDTIAGKMLENPVLMGFGSHSANEVRYLYHSDYAAVDFYNSGQYKNSVVDNDIDKALQATSWQASLPFWLAAEKQIVKDQPWTWLVNLQHLYAASTCLDLGQPITEPHGHGWPITENIEQWRWTCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z466</accession>
    <name>D0Z466_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Toxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000322</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304038.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000322"/>
    <dbReference type="EnsemblBacteria" id="EEZ39304">
        <property type="protein sequence ID" value="EEZ39304"/>
        <property type="gene ID" value="VDA_000322"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1502">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="104883at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019637">
        <property type="term" value="P:organophosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="SMART" id="SM00155">
        <property type="entry name" value="PLDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PLD phosphodiesterase" evidence="1">
        <location>
            <begin position="179"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="1">
        <location>
            <begin position="555"/>
            <end position="578"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="618" mass="70198" checksum="4876AA3D3B2721D4" modified="2010-01-19" version="1">MSKIDAVKAELVDKGFFYHDSKNNYVKLLDIPNIWGLPFGPEIMPRAYERQAEFERSVVEIIQKSRYRCDLASLNSPDPDWGKAILGAIDTTMTTKMGRTELTQFRFIFGQTPFYPVYEAPDLTLLKESLVRLIKERGQYWEVMPEFVVGRFFERVAGSLQSLQKKILPADLVSDYGTKMTWNHAKIISVDGFESLMGGHNLNMDLFRSYPPVHDVSAVFHGDASYGAQLFLNNMWVADTYLLTKESLDLDSLEWINRDSEPDYPSDPLTLSYVQDYMQEQQSKLLDIHESGVQPGVDPEQSILAPLPPVNDIKEFDLRSVQDLQHPVFEERITYNAYDGLEKYKKADRILTLGKYWTGPNRESDFKIGAEVMKKNLILNAKKVVRMSQQDIVSAWKKNWKDHSVCQWIIEALLKNPELEVQVVVSPLDAGAGAAGDQYSFGSGAIRTFGLMKYYMTHDVDTDELLDDSDGKRADALTRLYIAPFYYTDQVPDDKQVEGETYKWPKLPPEGRTASLKQRTLAEEPPHHGIIGHPFYATINASGFFFPRVGAAPGNHAKIMIIDDEACIVGSDNLYPGNLTELDNLIEGDFVQELLDNYWNPLWKYSSPHAYNGDGTTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z497</accession>
    <name>D0Z497_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glyco_hydro_63 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000353</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000353"/>
    <dbReference type="EnsemblBacteria" id="EEZ39335">
        <property type="protein sequence ID" value="EEZ39335"/>
        <property type="gene ID" value="VDA_000353"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3408">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004555">
        <property type="term" value="F:alpha,alpha-trehalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005991">
        <property type="term" value="P:trehalose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001661">
        <property type="entry name" value="Glyco_hydro_37"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031335">
        <property type="entry name" value="Glyco_hydro_63_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23403">
        <property type="entry name" value="PTHR23403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03200">
        <property type="entry name" value="Glyco_hydro_63"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro_63" evidence="1">
        <location>
            <begin position="646"/>
            <end position="849"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="859" mass="96328" checksum="051C4F6D9B66D5AE" modified="2010-01-19" version="1">MLTGCFDSDNSGIFNKVNPQPTLASQYKNVLDRTGTPNHLIEVGNGNHMAYTPLHDNGAWHGHLLPNLKAAPETAGGFGTTLIAEEYNVSLAQYLDKISVSIDGKKVNFTTEAYSIAGALIQKMTSSEGISIEMTMRFVSGRSSLLETKITNPTGKELTIELDGKLVTDYYAKNGNAAKETINEKLPNYTREVSSDDNGDITIDFGRERASWYVRTTGESEFHITRNLATTTKFTDDNYQSVAKIDGNQTIYTVFTHTMTADEWNTEQGVVEDILNHPDNYIAKNVTRWEDYLAKGLSNPNASKEQERVAVKAIETLNGNWRSPAGVLSHDTVTPSVTARWFSGNLTWPWDTWKQAYAMAHFNPNIAMENIRAVFQYQIQDNDTLRPYDKGFLLDVVGMNMSDIRGEAEGRTEFNDAQTWNERNTKPSLASWAVWEVYTALKNEHNREADAQAWLEEMYPKLKAYHDWWLAARDTNNNGIPEYGATVDPEHTTKDGQLIYFYKPNAQSDWIEASGIDNYNDLLESGNYVDISSPAQTAASWESGRDDAAVFGFIDTIADANGYDSLSETEAQKIDQLGRYAKDKYGFDNKLNMGTDGEGKTLVTYSNTSAENTAKLNQAKKDWQVKFSENKDEKGEVIGYSLYQESIDQASYWYSDNNYLAKIATELGLGNEATEFTKKANETKDYINKCMFDKETGFFYDISIDNTQAQELNNGCAGKPLVNRGMGAEGWSPLFNEAATQEHADAVVDNMLNEKKFNTKVPLGTAAKDNPAYGADIYWRGRVWVDQFYFGVKGLDNYGYNKEAVELTNKLFANAEGLTQDKPIQENYNPETGAVQGANNFSWSSAHLYMLYNKFFKAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4N2</accession>
    <name>D0Z4N2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">GGDEF family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_000490</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304509.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000490"/>
    <dbReference type="EnsemblBacteria" id="EEZ39470">
        <property type="protein sequence ID" value="EEZ39470"/>
        <property type="gene ID" value="VDA_000490"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2199">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3614">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901564">
        <property type="term" value="P:organonitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006796">
        <property type="term" value="P:phosphate-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044238">
        <property type="term" value="P:primary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006189">
        <property type="entry name" value="CHASE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042240">
        <property type="entry name" value="CHASE_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03924">
        <property type="entry name" value="CHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01079">
        <property type="entry name" value="CHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50839">
        <property type="entry name" value="CHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="331"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="domain" description="CHASE" evidence="5">
        <location>
            <begin position="77"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="6">
        <location>
            <begin position="402"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="532" mass="61116" checksum="11E98C4B30E401F4" modified="2010-01-19" version="1">MAFRYIIKSNKKTRIPSFVCLCILFATALVGYIFHTVYQQNHMNNFKNLVTHQTYLLQNQIENDLQFMGSMANFLEASSNANWQNFELFAQPIIQNSKGLIALQLQQRVSSSNIHKFTQEYRFLGKPITPYTLDNGRVLSFNDVKQDQTLFITTKVYPVNKENLSVIGFYSLGDRTRLILNNISHSRKANISDRVRLLQDKHSFITHLKAPLKGKDNLEQVIPDKIRLSSPKRGMLIYYPVFQHNEMTAVVIGVVDVTIYLKTLITQAIENHHSAIQIIDTGFGANDSPILYQSPSWKSTDGVEITTQISYPNRSWLLHFKQSTDFDMNEYWILGAIFIVGLVIALLASLVTYQQLSQNQRLQYALTERTKELEFLVNHDSLTRLLNRRAFRLTLPLWIESKQFTLVGFDIDKFKSINDTYGHIAGDEALIHVTQLVQGLLQKHEQLYRLGGDEFAILMPETDTTKIYEVLNRVRSAVEHSPLIYQGAKIYCTLSIGAVVHSNQEAEALIYQSDLQMYKSKQQGRNRISITY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4N4</accession>
    <name>D0Z4N4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">Cryptochrome DASH</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_000492</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">May have a photoreceptor function.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
        </cofactor>
        <text evidence="5">Binds 1 5,10-methenyltetrahydrofolate (MTHF) per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="5">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the DNA photolyase class-1 family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304514.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000492"/>
    <dbReference type="EnsemblBacteria" id="EEZ39472">
        <property type="protein sequence ID" value="EEZ39472"/>
        <property type="gene ID" value="VDA_000492"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0415">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="184000at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003913">
        <property type="term" value="F:DNA photolyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014133">
        <property type="entry name" value="Cry_DASH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036134">
        <property type="entry name" value="Crypto/Photolyase_FAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036155">
        <property type="entry name" value="Crypto/Photolyase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005101">
        <property type="entry name" value="Cryptochr/Photolyase_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002081">
        <property type="entry name" value="Cryptochrome/DNA_photolyase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006050">
        <property type="entry name" value="DNA_photolyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11455">
        <property type="entry name" value="PTHR11455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00875">
        <property type="entry name" value="DNA_photolyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03441">
        <property type="entry name" value="FAD_binding_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00147">
        <property type="entry name" value="DNAPHOTLYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48173">
        <property type="entry name" value="SSF48173"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52425">
        <property type="entry name" value="SSF52425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02765">
        <property type="entry name" value="crypto_DASH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51645">
        <property type="entry name" value="PHR_CRY_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0157">Chromophore</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Photolyase/cryptochrome alpha/beta" evidence="7">
        <location>
            <begin position="2"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="56"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU367151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ39472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="436" mass="51520" checksum="4014228E26102B5C" modified="2010-01-19" version="1">MKTGLYLFQNDLRLHDNLALLNATTQCDRLLLVYCLPYHQANRYPYHIHNYGALRLQFLLQSLHQLHQQLQDLEQELLVFLEHPLHILPQLISQYDIHTIISSEQVGYYENQTWQTLNQRYPYIEFKQWPTHTLLHKEQLPFDLNKLPSTFSQFRRQVEHIELTPLTPYISHLPPSPNKIAHISILDSFISHPKPSDFIGGEATAISHLTAYFKSDKASRYKETRNDLDGWDYSTKFSPWLAQGCLSAKRVIYELNQYHHQVDETPSSQWIKFELLWREYFQWYAHHHQQKIFQFKGIKSSSPHTSFYPERFKRWSESNTPYPLVNALMRQLITTGYMSNRGRQIVASCFVNELELDWRYGAAFFEQHLIDYDIASNWGNWQYLAGVGADPKGNRHFNLDKQTELFDPQGQFITKWNGNNHDGKIDSVDAADWPIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4P0</accession>
    <name>D0Z4P0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NfeD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000498</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39478">
        <property type="protein sequence ID" value="EEZ39478"/>
        <property type="gene ID" value="VDA_000498"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002810">
        <property type="entry name" value="NfeD-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01957">
        <property type="entry name" value="NfeD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NfeD" evidence="2">
        <location>
            <begin position="3"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="37" mass="3958" checksum="E29AD8EFB543ABC6" modified="2010-01-19" version="1">MNLGDTTWAVRCNEDLPAGTKIVVIDVEGIILVVKAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4P5</accession>
    <name>D0Z4P5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF3644 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000503</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304554.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000503"/>
    <dbReference type="EnsemblBacteria" id="EEZ39483">
        <property type="protein sequence ID" value="EEZ39483"/>
        <property type="gene ID" value="VDA_000503"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502Z8HD">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="641713at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022104">
        <property type="entry name" value="DUF3644"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12358">
        <property type="entry name" value="DUF3644"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3644" evidence="1">
        <location>
            <begin position="120"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="415" mass="47983" checksum="9D1B99283440F203" modified="2010-01-19" version="1">MSRYDKVDLAYKFLSSKENEGESFTIDELAKATGWKKQTCGTYPSKRWHQYVQKDGSHYLTTGIKFLSKDEFRAVHSQKLQQVADQSAKGMLLHKAREFALLAVSTYNNPYTEFKTYGYIVNIVIAYTALFHAIFEKKGIDYFHLKDGKPVIIDGEEKAWELMECCNQYWNGVERPEKYNLQFLIGLRNKIEHRSLPAIELAVAGECQAALINFENLLAEEFGDSHALCTNLAIAMQLSRISEQAQIDAMKQLQKENYKVVRHYMETYRADLEDNIVESQQYRIRAMLVPKLGNHAKSSDIAVEFINVNKLTEEELQNYEQGVAFIKGIENPYKLKPSKVMALVREKLPFFNMPLHTKCWKYFEARPRDNAPAFKGEYASFIEGFDGYLYTKQWVTFLTTELKKPEVLAKVKKAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4S1</accession>
    <name>D0Z4S1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hydroxymethylpyrimidine ABC transporter substrate-binding component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000529</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304636.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000529"/>
    <dbReference type="EnsemblBacteria" id="EEZ39509">
        <property type="protein sequence ID" value="EEZ39509"/>
        <property type="gene ID" value="VDA_000529"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0715">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027939">
        <property type="entry name" value="NMT1/THI5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015168">
        <property type="entry name" value="SsuA/THI5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31528">
        <property type="entry name" value="PTHR31528"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09084">
        <property type="entry name" value="NMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019417" evidence="1">
        <location>
            <begin position="23"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="NMT1" evidence="2">
        <location>
            <begin position="37"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="315" mass="34728" checksum="63728DC5B297BB25" modified="2010-01-19" version="1">MKTATKTALTIVLTSCSFNLWAAQEQNISLMLDWFVNPNHGPIIIAQEQGLFAKEGLKVTIQEPADPSVPAKLVAANKVDLAISYQTSLTTDVAAGLPLIRSATLIATPLNTLMTLDNGKIKSIADLKGKKIGIAVAGNEEATLGTMLKTAGINYKDVQIINVGWALSSSLASGKVDAIWGGLRNFETNQLALEGYKAKAYYPEEYGVPSYDELVIVANKNHYNKATIKKFNHALELATQYIVNHPVQAWQTFIKYNPDTLNNELNHRAWNDTIARFALRPSAVDLERYNKLASFMYQHHIINNEPKAKDYVPAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4V8</accession>
    <name>D0Z4V8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Type III secretion host injection protein (YopB)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000191</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306562.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000191"/>
    <dbReference type="EnsemblBacteria" id="EEZ39175">
        <property type="protein sequence ID" value="EEZ39175"/>
        <property type="gene ID" value="VDA_000191"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5613">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="994831at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006972">
        <property type="entry name" value="SseC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04888">
        <property type="entry name" value="SseC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="170"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="197"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="238"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="111"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="324"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="373" mass="39264" checksum="75A4CAE7F1E84500" modified="2010-01-19" version="1">MNYIAPDRTQSQVYTPDSDQTTLDKVTKTASHASPSVTVENVKSKDAEALNIGKTKVQLDAPNAAVSDKVNELTLKAMAKLQKIVDSIAKVLYAVADNTGSLAVRIIAGSVDDFEVELAAITDKLKSAQNELRIQEVKVAKAKHEQEMAENQEKIKESESAAKEAQKSGLAAKIFGWISAVASIIIGSIMVATGIGAVAGALMIAGGILGVVSATIQEPAVQDAMKEAGINIDALQKAIMAFEIAVAVIGAVVTVGAFFSASIAKIAEMGSKTATMTTRVINLTTESIDIAINTGKGITDSINSKKSANVATIQAEITNLKSSMTLSQAVLDKLKEEIAKLIEDFQELMSVIMQMIQAKGETLQAVMSRPATV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4V9</accession>
    <name>D0Z4V9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type III secretion LcrG inhibitor (LcrV,secretion and targeting control protein V antigen)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000192</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306565.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000192"/>
    <dbReference type="EnsemblBacteria" id="EEZ39176">
        <property type="protein sequence ID" value="EEZ39176"/>
        <property type="gene ID" value="VDA_000192"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502ZVN5">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="487062at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005413">
        <property type="entry name" value="LowCa_resp_V_Ag"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036139">
        <property type="entry name" value="Vir_assoc_V_ag_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04792">
        <property type="entry name" value="LcrV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01592">
        <property type="entry name" value="LCRVANTIGEN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103388">
        <property type="entry name" value="SSF103388"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="608" mass="67477" checksum="97F47088F36066F9" modified="2010-01-19" version="1">MTDMTTMNSVSGVLNTATNRDYQASFQQRLVETLSPILGDSDAAQLESLIRQLPMVVGRTEQDSLDLYADSLRTLLEKQAAFTGTAAAETAAHWMQLLQHQAVNGQIAPQDVMTGVNNTLAHQFQSWFDKQLKDTVDSSLPTDFINEFRLGSQSTQAQQIAALDASALTAATAEVSKFVDALAQQMSSSEVRDSAISFLRNAFRNLVSVDVNGLKNSDYLLTQESFSAAVTAQLVASLDSVDIKLSKSDADVLAGKIAWIPGMSKQELNDALNDLAKQVKGQFANSYTAGGKDELQAALDTVVNELNNSPNEITLSSLLSSIAVSLVNTQVDAFYGGLEDVQVTQATPDQVALIKQSTARDITLLFEKIVARQDSGTDFTSRHKKMLENLDALKIRLSKITKEEKDNKAVNAEHALTARDLLSVIESSIGDRFDERVLFALNERRVNRLEKRNEQKQVLEELTIRLKFFGVVQSRIHSFQSRDASYDPFGVEGRFKASDFNYSNDNEFKASPEYKYLSKNKIEKHGDFLRKEGLTVPYDVSYQDTKDNKKLSNFSSSVSDKSKLLNDEVQIKTTELNDTSSQYNSTVEAMNKFVQKYHSILQEILRAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-06-02" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z526</accession>
    <name>D0Z526_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000259</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39243">
        <property type="protein sequence ID" value="EEZ39243"/>
        <property type="gene ID" value="VDA_000259"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="43" mass="4681" checksum="A6B06BDBE7A92CC3" modified="2010-01-19" version="1">MTHSANHHSTITKPLEATQGVALSTQAPTKMNHLRAKAKQKSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z537</accession>
    <name>D0Z537_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000272</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306788.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000272"/>
    <dbReference type="EnsemblBacteria" id="EEZ39254">
        <property type="protein sequence ID" value="EEZ39254"/>
        <property type="gene ID" value="VDA_000272"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502Z9Z1">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="170450at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014121">
        <property type="entry name" value="TraN_Ftype"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06986">
        <property type="entry name" value="TraN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02750">
        <property type="entry name" value="TraN_Ftype"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019428" evidence="1">
        <location>
            <begin position="19"/>
            <end position="605"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="605" mass="67152" checksum="6BF9A9117C07081E" modified="2010-01-19" version="1">MKNLFIFTLLTCSSWVYANAIGQNYYNEVGNAKTMLNNKLASPSLRGFTGDDYCKDESCRQQMHNPTQGQYFGHETELESNAKQRLANDPYAANIAGSMDSRPNAKYKVNPNDPAFSSAKDYMDHSYEISHGISNKYVDCEGGNICKFEQSAKQCQIPTGNQPSCYSEAYLKNVSLVKDQHLIPVRGEFGRLSLPKSMMVSQIDLPALRQVPQTMPIGCEEATSPRDLAVFINGQQVSSVRGSLDLSGYWGGCRISLATPATSILFNPPRQLSSLLIDYSSAHNFNMVGHGNIVVHTNKEKIEMGWRDNCPAFTRECRAVKETCMEGAGTRKINGIDVHMSCWKKQRTYQCQYEDTCRPIHQDKASFGDCKETKRTCKSSLLGQCMAFDIALDCSKRTCKQRNLTCGDRFFCLDGHCYDEKMEQNQGFSKSASALAAIGDAGKALNVDSMKIFTGKGVSCSKKPIGFSDCCADKGWGQGIGLAKCSEEEKGLAKAKEKGLTIDLGTYCAEKVLGACIRKKKGYCQFDSKMARIVQEQGRSRLGLNFGSAKHPDCSGISPEQLQKIDFSQIDFSEFYQDLEQNMKLPNPASIQERITDKYKDLGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z574</accession>
    <name>D0Z574_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">IncF plasmid conjugative transfer pilus assembly protein TraK</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000033</name>
        <name evidence="3" type="ORF">VDA_000124</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000005">
        <property type="protein sequence ID" value="EEZ39048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="ADBS01000004">
        <property type="protein sequence ID" value="EEZ39108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306914.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000005.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39048">
        <property type="protein sequence ID" value="EEZ39048"/>
        <property type="gene ID" value="VDA_000033"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39108">
        <property type="protein sequence ID" value="EEZ39108"/>
        <property type="gene ID" value="VDA_000124"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2375">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1450250at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010563">
        <property type="entry name" value="Pilus_assembly_TraK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014126">
        <property type="entry name" value="TraK_Ftype"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06586">
        <property type="entry name" value="TraK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02756">
        <property type="entry name" value="TraK_Ftype"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5007650153" evidence="1">
        <location>
            <begin position="18"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="233" mass="25167" checksum="921DA4D6F35C9ED7" modified="2010-01-19" version="1">MKSLLLLAALLPAVAVAAPPTTIPFSNNETITLNLSSMDINRLVVQDDKITSVTCPTGFCTLPISEEGAGVDPQGAALITIDVLEPFTLYVTTQKGRSFGAFVRPLAVPAVTTLLVSTDRDTEQAAKFEHQSPYSETLARLIRHMVTDTQPDGFLKQSVTSKPSPFGLFSLQALRSYQGESLTGVVYYLKNPTTQAVTIEPDSFYQKGVYAVAFSANRIPPGGSIYLYQITGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5C2</accession>
    <name>D0Z5C2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000029</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000005">
        <property type="protein sequence ID" value="EEZ39044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000029"/>
    <dbReference type="EnsemblBacteria" id="EEZ39044">
        <property type="protein sequence ID" value="EEZ39044"/>
        <property type="gene ID" value="VDA_000029"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0582">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007069">
        <property type="entry name" value="Transposase_32"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04986">
        <property type="entry name" value="Y2_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="323" mass="38417" checksum="4371EFF9F0C7D2EB" modified="2010-01-19" version="1">MLTEKWIAKQLSILPKYEYQHMTLTMPDKLWPIFRLNPWLINLLYRCAVSAFLSFAKKRGIEIGLFCVVHTFGRQLNWNVHFHLSVTRGGVNIKTKRWGNIYFNAAMVEQHWKQQVVSFLRDHYNALNTKHDNYQHIRDFRGWSQFLSSQYSRKWRIHLAKKTEDVGPTVRYLGRYFKRPPIAASRLRHYQGGDVHFVYKDHRDNCYKTLVLSQIEMIDRLVSHIPAEKNFRAIRYYGFLSNRKRGEALPLVYDLLDQEEPVEPKPLNYAQMMHHLVGIDPYKCILCGGRMCFVKMEMGLKGHELVALRKATIREKRRLRYSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5G6</accession>
    <name>D0Z5G6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000073</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000006">
        <property type="protein sequence ID" value="EEZ39018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005307155.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000006.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39018">
        <property type="protein sequence ID" value="EEZ39018"/>
        <property type="gene ID" value="VDA_000073"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="277" mass="32466" checksum="5B830ABDA7C4D5F2" modified="2010-01-19" version="1">MSASKHKHPKNLPVSSSSDRQTAVKKRITELGSRKNEFKKSYFPYYTKRLLLAFANFIDNPHGYNNQLHDLYYCQSIIYGLQERQRENCVKVMTVLCSWLEVETNQIGLAKHEHMDTVTHGSVIKRYNKFWGESISLKRYYHTIKLLKMADYLVIDAIFLQDADILSNLDLKDEELPRVYSKAAYKSLTQKFVNIFGLHTDDGVMKSKRRSITKRIKAGLQTMWVTWQSFSDTYQWIKRQRANLKRVDPITHEESERYPQGRTIDSSILGGNYITEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVI3</accession>
    <name>D0YVI3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Putative 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase</fullName>
            <shortName evidence="4">SHCHC synthase</shortName>
            <ecNumber evidence="4">4.2.99.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">menH</name>
        <name evidence="6" type="ORF">VDA_001563</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-carboxylate = (1R,6R)-6-hydroxy-2-succinyl-cyclohexa-2,4-diene-1-carboxylate + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:25597"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:58689"/>
            <dbReference type="ChEBI" id="CHEBI:58818"/>
            <dbReference type="EC" id="4.2.99.20"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Quinol/quinone metabolism; 1,4-dihydroxy-2-naphthoate biosynthesis; 1,4-dihydroxy-2-naphthoate from chorismate: step 3/7.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Quinol/quinone metabolism; menaquinone biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the AB hydrolase superfamily. MenH family.</text>
    </comment>
    <dbReference type="EC" id="4.2.99.20" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298283.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001563"/>
    <dbReference type="ESTHER" id="lisda-d0yvi3">
        <property type="family name" value="MenH_SHCHC"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40537">
        <property type="protein sequence ID" value="EEZ40537"/>
        <property type="gene ID" value="VDA_001563"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1196738at2"/>
    <dbReference type="UniPathway" id="UPA00079"/>
    <dbReference type="UniPathway" id="UPA01057">
        <property type="reaction ID" value="UER00900"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070205">
        <property type="term" value="F:2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009234">
        <property type="term" value="P:menaquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01660">
        <property type="entry name" value="MenH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022485">
        <property type="entry name" value="SHCHC_synthase_MenH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03695">
        <property type="entry name" value="menH_SHCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 4 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="1 4" id="KW-0474">Menaquinone biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="5">
        <location>
            <begin position="22"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="274" mass="30319" checksum="012AA80FEB9C0F59" modified="2010-01-19" version="1">MRLYSEIFLPKQSLSDSSCPTLVFLHGLLGNGRDWRHVIDELSHDYPCITLDLPGHGFSVEAIPTSFEQVTQAILETLAARNIERYILIGYSMGGRLAMHTVCQPLLTPNATSQISQPSLLGALLGVVIEGGNPGIEPELQAARWNNDTHWARRFDSEPLPQVLADWYQQSVFSSLNYDQRQSLIVKRSHNSGSGVARMLLATSLAKQPQLAAVLPQVTAPMLYICGKKDQKFCELATQLDLDYTIIEQAGHNVHVEAPHAFAAQIRTFIQSVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVK3</accession>
    <name>D0YVK3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glyceraldehyde-3-phosphate dehydrogenase</fullName>
            <ecNumber evidence="8">1.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_001583</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.-" evidence="8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298326.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001583"/>
    <dbReference type="EnsemblBacteria" id="EEZ40557">
        <property type="protein sequence ID" value="EEZ40557"/>
        <property type="gene ID" value="VDA_001583"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0057">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="944149at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020831">
        <property type="entry name" value="GlycerAld/Erythrose_P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020830">
        <property type="entry name" value="GlycerAld_3-P_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020829">
        <property type="entry name" value="GlycerAld_3-P_DH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020828">
        <property type="entry name" value="GlycerAld_3-P_DH_NAD(P)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006424">
        <property type="entry name" value="Glyceraldehyde-3-P_DH_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10836">
        <property type="entry name" value="PTHR10836"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02800">
        <property type="entry name" value="Gp_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00044">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000149">
        <property type="entry name" value="GAP_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00078">
        <property type="entry name" value="G3PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00846">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01534">
        <property type="entry name" value="GAPDH-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00071">
        <property type="entry name" value="GAPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 8 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gp_dh_N" evidence="9">
        <location>
            <begin position="3"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Glyceraldehyde 3-phosphate binding" evidence="4">
        <location>
            <begin position="149"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Glyceraldehyde 3-phosphate binding" evidence="4">
        <location>
            <begin position="209"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="150"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="12"/>
            <end position="13"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="314"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="site" description="Activates thiol group during catalysis" evidence="6">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ40557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="331" mass="35234" checksum="838A5EAD8F22CD22" modified="2010-01-19" version="1">MTIKVGINGFGRIGRFVFRAAQERNDIEVVGINDLIDVEYMAYMLKYDSTHGRFNGTVEVEGGNLIVNGKTVRVTAERNPADLKWDAINVDVVAEATGLFLTDETARKHIEAGAKKVVLTGPSKDATPMFVMGVNHETYTGQDIVSNASCTTNCLAPIAKVLNDNFGIESGLMTTVHATTATQKTVDGPSAKDWRGGRGASQNIIPSSTGAAKAVGVVLPEVNGKLTGMAFRVPTANVSVVDLTVNLKNGASYETICKAMKDASEGSLKGILGYTEDAVVSTDFNGDTRTSIFDAAAGIALSDNFVKVVSWYDNEIGYSNKVLDLIAHISK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVQ3</accession>
    <name>D0YVQ3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RNA polymerase-binding transcription factor DksA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">dksA</name>
        <name evidence="8" type="ORF">VDA_001218</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Interacts directly with the RNA polymerase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the DksA family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297660.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001218"/>
    <dbReference type="EnsemblBacteria" id="EEZ40196">
        <property type="protein sequence ID" value="EEZ40196"/>
        <property type="gene ID" value="VDA_001218"/>
    </dbReference>
    <dbReference type="GeneID" id="57339925"/>
    <dbReference type="eggNOG" id="COG1734">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1932026at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00926">
        <property type="entry name" value="DksA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012784">
        <property type="entry name" value="DksA_RNA_pol-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037187">
        <property type="entry name" value="DnaK_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000962">
        <property type="entry name" value="Znf_DskA_TraR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020458">
        <property type="entry name" value="Znf_DskA_TraR_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01258">
        <property type="entry name" value="zf-dskA_traR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109635">
        <property type="entry name" value="SSF109635"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02420">
        <property type="entry name" value="dksA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01102">
        <property type="entry name" value="ZF_DKSA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51128">
        <property type="entry name" value="ZF_DKSA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DksA C4-type" evidence="7">
        <location>
            <begin position="69"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="dksA C4-type" evidence="6">
        <location>
            <begin position="112"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ40196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="149" mass="17150" checksum="2F89B421BB2F6AE5" modified="2010-01-19" version="1">MPESNVKKSLGILAIAGVQPYQEKAGEEYMGEAQLEHFRKILDAWRNQLREEVGRTVNHMQDEAANFPDPVDRAAQEEEFSLELRNRDRERKLIKKIEKTLQRIEDDDFGFCDSCGIEIGIRRLEARPTAELCIDCKTLAELKEKQMAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVT7</accession>
    <name>D0YVT7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N-acetyl-D-glucosamine kinase</fullName>
            <ecNumber evidence="2">2.7.1.59</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">GlcNAc kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">nagK</name>
        <name evidence="3" type="ORF">VDA_002018</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + N-acetyl-D-glucosamine = ADP + H(+) + N-acetyl-D-glucosamine 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:17417"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57513"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="ChEBI" id="CHEBI:506227"/>
            <dbReference type="EC" id="2.7.1.59"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cell wall biogenesis; peptidoglycan recycling.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ROK (NagC/XylR) family. NagK subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.59" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299190.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002018"/>
    <dbReference type="EnsemblBacteria" id="EEZ40986">
        <property type="protein sequence ID" value="EEZ40986"/>
        <property type="gene ID" value="VDA_002018"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1940">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1130699at2"/>
    <dbReference type="UniPathway" id="UPA00544"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045127">
        <property type="term" value="F:N-acetylglucosamine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006044">
        <property type="term" value="P:N-acetylglucosamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009254">
        <property type="term" value="P:peptidoglycan turnover"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01271">
        <property type="entry name" value="GlcNAc_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023505">
        <property type="entry name" value="N-acetyl-D-glucosamine_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01125">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="1 2" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="4"/>
            <end position="11"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="133"/>
            <end position="140"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="303" mass="32604" checksum="8B85DCE6FFA7DAE7" modified="2010-01-19" version="1">MYYGFDVGGTKIEFGAFNEKLERVATERVPTPSDDYQQLIDTIVAIIQKADQEFGCEGHVGIGIPGMEDARDGTVLTSNIAAAKGKPLRKDLEAKLGRSVTIDNDANCFALSEAWDEALQDEKSVLGLILGTGFGGGIVIDGKAFSGMNHVAGELGHARLPLDAWFHLGENAPLLSCGCGNKGCIDNYLSGRGFELLYAHYYGEELKAIEIIKRNAEGEPKAVEHVDRFMELLAICFANIFTGLDPNVVVLGGGLSNFDLIYDEVPKRIGKHLLSVAQPPKIVKAKHGDAGGVRGAAFLNIQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>D0YVV5</accession>
    <name>D0YVV5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002036</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41004">
        <property type="protein sequence ID" value="EEZ41004"/>
        <property type="gene ID" value="VDA_002036"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="50" mass="5692" checksum="9B40FB4F86E4D1A5" modified="2010-01-19" version="1">MVVYEVIKDNGYQREFDSADLDLFIQEAKKLGVSEIKFESGGVEKDIPIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>D0YW20</accession>
    <name>D0YW20_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 9">DNA mismatch repair protein MutS</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">mutS</name>
        <name evidence="13" type="ORF">VDA_001280</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 9">This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9 10">Belongs to the DNA mismatch repair MutS family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001280"/>
    <dbReference type="EnsemblBacteria" id="EEZ40258">
        <property type="protein sequence ID" value="EEZ40258"/>
        <property type="gene ID" value="VDA_001280"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0249">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00096">
        <property type="entry name" value="MutS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005748">
        <property type="entry name" value="DNA_mismatch_repair_MutS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007695">
        <property type="entry name" value="DNA_mismatch_repair_MutS-lik_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017261">
        <property type="entry name" value="DNA_mismatch_repair_MutS/MSH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007861">
        <property type="entry name" value="DNA_mismatch_repair_MutS_clamp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007696">
        <property type="entry name" value="DNA_mismatch_repair_MutS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016151">
        <property type="entry name" value="DNA_mismatch_repair_MutS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007860">
        <property type="entry name" value="DNA_mmatch_repair_MutS_con_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036678">
        <property type="entry name" value="MutS_con_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS_family"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="PTHR11361"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01624">
        <property type="entry name" value="MutS_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05188">
        <property type="entry name" value="MutS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05192">
        <property type="entry name" value="MutS_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05190">
        <property type="entry name" value="MutS_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037677">
        <property type="entry name" value="DNA_mis_repair_Msh6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00533">
        <property type="entry name" value="MUTSd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="SSF48334"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53150">
        <property type="entry name" value="SSF53150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55271">
        <property type="entry name" value="SSF55271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01070">
        <property type="entry name" value="mutS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00486">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 9 10" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 9 10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 9 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA_MISMATCH_REPAIR_2" evidence="12">
        <location>
            <begin position="720"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="829"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="646"/>
            <end position="653"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS00486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ40258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="898" mass="99837" checksum="768AC3733C14DD14" modified="2010-01-19" version="1">MTRFTYPKQPEFYTSETTWLLSHSLAKAGVIVTVQGLEKHTPMMQQYLKIKAENPDVLLFYRMGDFYELFYDDAKQASKLLDISLTKRGASNGQPIPMAGVPHHAAEGYLAKLVQQGVSVAICEQIGDPATSKGPVERQVVRIVTPGTVSDEALLNERRDNLIAAIFAYNDGFGYATLDITSGRFMLTEPNTEEEMQAELQRTMPAELLYPEDFTYLHLIESFKGKRRRPVWEFELSTARQQLTMQFGTRDLVGFGVEHAERGLCAAGCLLQYVKDTQRTALPHIRAITLDTKDHAVILDAATRRNLELTQNLAGGFDNTLASVLDQTATPMGSRLLKRWLHQPIRDPKQLNGRYNAIGAFKDSGLFSELAGVLRHMGDLERILARLALRSARPRDLARMRIALQNLPELADLLAEVSDPRIGELAALAAPMDEVCQLLEHAIIENPPVIIRDGGVLAPGYNAELDEWRDLADGATKYLEELEARERERHDIDSLKVGFNQVHGFYIQVSRGQSHLVPSHYIRRQTLKNAERYIIPELKEHEDKVLNSKSKALALEKKLWDELFDLLMPNLEQLQNMANSLSELDVLANLAERADTLNYCRPQLMDETGIEIEAGRHPVVEQVLSEPFIANPISLNHDRRMLIITGPNMGGKSTYMRQTALIALLAHVGSFVPADSLKIGPLDRIFTRIGASDDLASGRSTFMVEMTETANILHNATQHSLVLMDEIGRGTSTYDGLSLAWASAEWLADKIAAMTLFATHYFELTELPTLMSGLANVHLDAVEHGDEIAFMHAVQEGAASKSYGLAVASLAGVPKSVIKRAKIKLQQLEASGHQQASDVPNPTTTDAPTSAKAVRQEHQLSLIPESSEVEEAVARLNPDNMTPREALDELYRLKALLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWD3</accession>
    <name>D0YWD3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phosphoribosylglycinamide formyltransferase</fullName>
            <ecNumber evidence="2">2.1.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">5'-phosphoribosylglycinamide transformylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">GAR transformylase</fullName>
            <shortName evidence="2">GART</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">purN</name>
        <name evidence="4" type="ORF">VDA_001403</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>(6S)-10-formyltetrahydrofolate + N(1)-(5-phospho-beta-D-ribosyl)glycinamide = (6S)-5,6,7,8-tetrahydrofolate + H(+) + N(2)-formyl-N(1)-(5-phospho-beta-D-ribosyl)glycinamide</text>
            <dbReference type="Rhea" id="RHEA:15053"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
            <dbReference type="ChEBI" id="CHEBI:143788"/>
            <dbReference type="ChEBI" id="CHEBI:147286"/>
            <dbReference type="EC" id="2.1.2.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; IMP biosynthesis via de novo pathway; N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide from N(1)-(5-phospho-D-ribosyl)glycinamide (10-formyl THF route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GART family.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.2" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298006.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001403"/>
    <dbReference type="EnsemblBacteria" id="EEZ40378">
        <property type="protein sequence ID" value="EEZ40378"/>
        <property type="gene ID" value="VDA_001403"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0299">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1815747at2"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00126"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004644">
        <property type="term" value="F:phosphoribosylglycinamide formyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd08645">
        <property type="entry name" value="FMT_core_GART"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01930">
        <property type="entry name" value="PurN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002376">
        <property type="entry name" value="Formyl_transf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036477">
        <property type="entry name" value="Formyl_transf_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004607">
        <property type="entry name" value="GART"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00551">
        <property type="entry name" value="Formyl_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53328">
        <property type="entry name" value="SSF53328"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00639">
        <property type="entry name" value="PurN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Formyl_trans_N" evidence="3">
        <location>
            <begin position="2"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="5'-phosphoribosylglycinamide binding" evidence="2">
        <location>
            <begin position="12"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="region of interest" description="10-formyltetrahydrofolate binding" evidence="2">
        <location>
            <begin position="91"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="110"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>(6S)-10-formyltetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>(6S)-10-formyltetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
        </ligand>
    </feature>
    <feature type="site" description="Raises pKa of active site His" evidence="2">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="215" mass="23455" checksum="8197889CB1FFA0C4" modified="2010-01-19" version="1">MKNIVVLISGNGSNLQAIMDSCANGTIKNARVAAVIANKADAYGLTRAQQANIDAVTLLASDFADRQAYEQALAKTIDGYHPDVVVLAGFMRILDSAFVHHYQGRIFNIHPSLFPKYPGLNTHQRALEAGDSEHGTTVHFVTPELDGGPVVLQAKVPIFPQDSIAEIEQRVQQQEYAIYPLVINWFLSQRLVMDEAGKALLDGHSLPLNGYASDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWF3</accession>
    <name>D0YWF3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Phosphoheptose isomerase</fullName>
            <ecNumber evidence="10">5.3.1.28</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Sedoheptulose 7-phosphate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">gmhA</name>
        <name evidence="12" type="ORF">VDA_001401</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 10">Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>2 D-sedoheptulose 7-phosphate = D-glycero-alpha-D-manno-heptose 7-phosphate + D-glycero-beta-D-manno-heptose 7-phosphate</text>
            <dbReference type="Rhea" id="RHEA:27489"/>
            <dbReference type="ChEBI" id="CHEBI:57483"/>
            <dbReference type="ChEBI" id="CHEBI:60203"/>
            <dbReference type="ChEBI" id="CHEBI:60204"/>
            <dbReference type="EC" id="5.3.1.28"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="10">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="10">Carbohydrate biosynthesis; D-glycero-D-manno-heptose 7-phosphate biosynthesis; D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate from sedoheptulose 7-phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="10">The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the SIS family. GmhA subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.28" evidence="10"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298003.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001401"/>
    <dbReference type="EnsemblBacteria" id="EEZ40376">
        <property type="protein sequence ID" value="EEZ40376"/>
        <property type="gene ID" value="VDA_001401"/>
    </dbReference>
    <dbReference type="GeneID" id="57339678"/>
    <dbReference type="eggNOG" id="COG0279">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1571626at2"/>
    <dbReference type="UniPathway" id="UPA00041">
        <property type="reaction ID" value="UER00436"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008968">
        <property type="term" value="F:D-sedoheptulose 7-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001061">
        <property type="term" value="P:D-glycero-D-manno-heptose 7-phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd05006">
        <property type="entry name" value="SIS_GmhA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00067">
        <property type="entry name" value="GmhA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035461">
        <property type="entry name" value="GmhA/DiaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004515">
        <property type="entry name" value="Phosphoheptose_Isoase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13580">
        <property type="entry name" value="SIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00441">
        <property type="entry name" value="gmhA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 10 12" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="SIS" evidence="11">
        <location>
            <begin position="37"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="52"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="93"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="119"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="65"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="172"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ40376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="192" mass="20926" checksum="22C0B7CAC8C1347A" modified="2010-01-19" version="1">MYQDLIRAELTEAAEVLNRFLSDDKNLADIEAAAKLLAESFKQGGKVLSCGNGGSHCDAMHFAEELTGRYRDNRPGYAGIAISDPSHLSCVSNDFGYEYVFSRYLEAVGREGDVLFGLSTSGNSGNILKAIEAARAKDMKVIALTGKDGGQMAGLADVEIRVPHFGYADRIQEVHIKIIHILIMLVEKEMAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWF5</accession>
    <name>D0YWF5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thiol peroxidase Bcp-type</fullName>
            <ecNumber evidence="2">1.11.1.15</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001414</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.11.1.15" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001414"/>
    <dbReference type="EnsemblBacteria" id="EEZ40388">
        <property type="protein sequence ID" value="EEZ40388"/>
        <property type="gene ID" value="VDA_001414"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1225">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AhpC-TSA" evidence="1">
        <location>
            <begin position="2"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="90" mass="10415" checksum="1BA2028C3BF8A795" modified="2010-01-19" version="1">MVLGISIDPVKRLPKFIERDQLNFTLLSDEDHAVADQFGVWGEKKFMGKVYDGLHRISFLINEDGVIEHVFNKFKTKDHHEVVLGYLNSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWJ8</accession>
    <name>D0YWJ8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 14">Transketolase</fullName>
            <ecNumber evidence="8 14">2.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">VDA_001239</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 14">Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = aldehydo-D-ribose 5-phosphate + D-xylulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:10508"/>
            <dbReference type="ChEBI" id="CHEBI:57483"/>
            <dbReference type="ChEBI" id="CHEBI:57737"/>
            <dbReference type="ChEBI" id="CHEBI:58273"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="2.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="14">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <cofactor evidence="14">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="14">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <text evidence="14">Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
        <text evidence="14">Binds 1 thiamine pyrophosphate per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7 14">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 14">Belongs to the transketolase family.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.1" evidence="8 14"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005297704.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001239"/>
    <dbReference type="EnsemblBacteria" id="EEZ40217">
        <property type="protein sequence ID" value="EEZ40217"/>
        <property type="gene ID" value="VDA_001239"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0021">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="188169at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004802">
        <property type="term" value="F:transketolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02012">
        <property type="entry name" value="TPP_TK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005478">
        <property type="entry name" value="Transketolase_bac-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020826">
        <property type="entry name" value="Transketolase_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033247">
        <property type="entry name" value="Transketolase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005474">
        <property type="entry name" value="Transketolase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43522">
        <property type="entry name" value="PTHR43522"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00456">
        <property type="entry name" value="Transketolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00232">
        <property type="entry name" value="tktlase_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00801">
        <property type="entry name" value="TRANSKETOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00802">
        <property type="entry name" value="TRANSKETOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 14" id="KW-0106">Calcium</keyword>
    <keyword evidence="12 14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13 14" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="9 14 16" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TRANSKETOLASE_1" evidence="15">
        <location>
            <begin position="17"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00002931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00007131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00013152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU004996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS00801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EEZ40217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="670" mass="72595" checksum="FBF1270EF08A59E4" modified="2010-01-19" version="1">MTSSNAISRKQLANAIRALSMDGVQQANSGHPGAPMGMADIAEVLWRGHMNHNPQNPNWADRDRFILSNGHGSMLIYSLLHLTGYDLAIDDLKNFRQLHSKTPGHPEYGYAPGVETTTGPLGQGITNAVGMALAEKALAAQFNREGHDIVDHHTYVFMGDGCMMEGVSHEACSLAGTLGLGKLIAFWDDNGISIDGHVEGWFSDDTPKRFEAYGWHVIPAVDGHDAEAINAAIEAAKAETTRPTLICTKTIIGFGSPNKAGSHDCHGAPLGAEEIKAAREFLGWEHGPFEIPADIYAQWDAKEAGSAKEVAWDEKFAAYAAQYPELAAEFKRRVNGELPANWEEATSAIIADLQANPANIASRKASQNALEAFGKLLPEFMGGSADLAPSNLTMWSGSKALTADDASGNYIHYGVREFGMTAIINGMALHGGFVPYGATFLMFMEYARNAMRMAALMKVQNIQVYTHDSIGLGEDGPTHQPVEQIASLRLTPNMSTWRPCDQVESAVAWKFAIERKDGPTALIFSRQNLAQQERDAQQLADITKGGYVLKDCDGKPELILIATGSEVELATEAYALLTAEGRKVRVVSMPATDVFDKQDAAYRESVLPSDVTARIAVEAGIADFWYKYVGFEGRIIGMTSFGESAPADQLFKLFGFTVENVVDTAKELLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0YWX1</accession>
    <name>D0YWX1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">LapA_dom domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_001804</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001804"/>
    <dbReference type="EnsemblBacteria" id="EEZ40772">
        <property type="protein sequence ID" value="EEZ40772"/>
        <property type="gene ID" value="VDA_001804"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3771">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010445">
        <property type="entry name" value="LapA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06305">
        <property type="entry name" value="LapA_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="domain" description="LapA_dom" evidence="6">
        <location>
            <begin position="2"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF06305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="70" mass="7945" checksum="83A266363A56E206" modified="2010-01-19" version="1">MLVNFDYLIAQGEFQLSTLLGIAFGAGFAIGWIICGILYLKARFTKNRLTKRVAKQQKELDQLRAEPVKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0YX91</accession>
    <name>D0YX91_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298998.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001950"/>
    <dbReference type="EnsemblBacteria" id="EEZ40918">
        <property type="protein sequence ID" value="EEZ40918"/>
        <property type="gene ID" value="VDA_001950"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1215">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="724641at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="314"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="351"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="390"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="438" mass="50552" checksum="BD1D078E9127997E" modified="2010-01-19" version="1">MIDSLNYIALTLITSLSQNSNNIFLFLPGFLLIELPLVILVISGVFRWGWHQDENQIVKYPSVSFIITCYGEGDAITQTVDTLVEQIYPGKIEILAIVDGAKQNNETYQAALRCAAKYKSIPFRKVRVIPKWQRGGRVSTLNSGLFFAKHDIVINVDGDTSFDNDMTINMVKHFQSSNTLAVGGALKVRNWQDNILTRMQAIEYMLSMQLGKTGMANWGVLNNISGAFGGFRRKILNHIGGWDTHTAEDLDLTVRLKQYKRRYPKTKLAFSPHAVGHTDVPSTIKGLIQQRLRWDGDLLFLYLRKHNKGLTPKLLGWGNFVFILVYGIFQNVILPLLVIIYLIYICMYAPWQIVLTINIILYLMYLVITSVYFILYINLISERPMKDIKFVVWLWLYPIYQFLMRIITAFSMFNELIRRSHEESNMAPWWVLKKGKRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXD0</accession>
    <name>D0YXD0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CBS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001670</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001670"/>
    <dbReference type="EnsemblBacteria" id="EEZ40643">
        <property type="protein sequence ID" value="EEZ40643"/>
        <property type="gene ID" value="VDA_001670"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0517">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="68" mass="7307" checksum="FD6C57B9B5DA4A91" modified="2010-01-19" version="1">MIKDVISVRTNDTLTKAISIILEHNVGAAPVLNKAGELVGMLSAIDLLQAFQDTLESQRSNKKKKSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXD1</accession>
    <name>D0YXD1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Anaerobic C4-dicarboxylate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_001671</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 8">Cell inner membrane</location>
            <topology evidence="3 8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 8">Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298489.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001671"/>
    <dbReference type="EnsemblBacteria" id="EEZ40644">
        <property type="protein sequence ID" value="EEZ40644"/>
        <property type="gene ID" value="VDA_001671"/>
    </dbReference>
    <dbReference type="GeneID" id="57342247"/>
    <dbReference type="eggNOG" id="COG2704">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="591678at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015556">
        <property type="term" value="F:C4-dicarboxylate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004668">
        <property type="entry name" value="Anaer_Dcu_memb_transpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36106">
        <property type="entry name" value="PTHR36106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03605">
        <property type="entry name" value="DcuA_DcuB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004539">
        <property type="entry name" value="C4-dicrbxl_trns"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00770">
        <property type="entry name" value="Dcu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="50"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="94"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="168"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="231"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="263"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="295"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="333"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="364"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="417"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR004539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ40644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="442" mass="47651" checksum="EA1F9FC3FBC50FE2" modified="2010-01-19" version="1">MLYLEFLFLLLVLYAGSRFGGIGLGVVSGLGLIVEVFIFRMPPTSPPITVMLIILAVVTCASILEAAGGLKYMLQVAERILRSNPKRVTILGPLVTYTMTFMLGTGHAVYSIMPIIGDVALKNGIRPERPMAASSVASQLAITASPISAAVVYYLAQLSGLNESIHLLTILMVTVPSTLLGTILLSLYSLRRGKELADDPEYQARLKDPIWAETIKNTTSTSLNEALPKSAMHAVMLFILALISIVIIAMVPEIRTIGDAKPISMSLVIQMMMLAFGGLILLVTRTNVQKVPEGVVFKSGMVAAIAIFGIAWMSDTYFQYAMPSFKSGITEMVQNYPWTFALALFIVSVVVNSQAATARMMLPVGLAMGLNPALLIGLMPATYGYFFIPNYPSDIATVNFDVTGTTKIGKWYFNHSFMAPGLIGVVGACVIGYLLAQVVVPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXE9</accession>
    <name>D0YXE9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Cyclic pyranopterin monophosphate synthase</fullName>
            <ecNumber evidence="3 5">4.6.1.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Molybdenum cofactor biosynthesis protein C</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">moaC</name>
        <name evidence="7" type="ORF">VDA_001628</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>(8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate = cyclic pyranopterin phosphate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:49580"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:59648"/>
            <dbReference type="ChEBI" id="CHEBI:131766"/>
            <dbReference type="EC" id="4.6.1.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homohexamer; trimer of dimers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the MoaC family.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.17" evidence="3 5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298402.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001628"/>
    <dbReference type="EnsemblBacteria" id="EEZ40601">
        <property type="protein sequence ID" value="EEZ40601"/>
        <property type="gene ID" value="VDA_001628"/>
    </dbReference>
    <dbReference type="GeneID" id="57342292"/>
    <dbReference type="eggNOG" id="COG0315">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1595361at2"/>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061799">
        <property type="term" value="F:cyclic pyranopterin monophosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01420">
        <property type="entry name" value="MoaC_PE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01224_B">
        <property type="entry name" value="MoaC_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023045">
        <property type="entry name" value="Mo_CF_biosynth-C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036522">
        <property type="entry name" value="MoaC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002820">
        <property type="entry name" value="Mopterin_CF_biosynth-C_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01967">
        <property type="entry name" value="MoaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55040">
        <property type="entry name" value="SSF55040"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00581">
        <property type="entry name" value="moaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 5" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MoaC" evidence="6">
        <location>
            <begin position="15"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="75"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="113"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ40601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="159" mass="17172" checksum="4872A2BBFE18BBA6" modified="2010-01-19" version="1">MTQFTHINASGEANMVDVSNKADTVREARAEAFVHMAPETLALIISGQHHKGDVFATARIAGIQAAKRTWDLIPLCHPLLLSKVEVQLEAIEAENKVRIESCCKLAGKTGVEMEALTAASVAALTIYDMCKAVQKDMVITQVRLLEKTGGKSGHFKAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXH3</accession>
    <name>D0YXH3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">7-methyl-GTP pyrophosphatase</fullName>
            <shortName evidence="3">m(7)GTP pyrophosphatase</shortName>
            <ecNumber evidence="3">3.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_001680</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>H2O + N(7)-methyl-GTP = diphosphate + H(+) + N(7)-methyl-GMP</text>
            <dbReference type="Rhea" id="RHEA:58744"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58285"/>
            <dbReference type="ChEBI" id="CHEBI:87133"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Maf family. YceF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.-" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298502.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001680"/>
    <dbReference type="EnsemblBacteria" id="EEZ40651">
        <property type="protein sequence ID" value="EEZ40651"/>
        <property type="gene ID" value="VDA_001680"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0424">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1469203at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047429">
        <property type="term" value="F:nucleoside-triphosphate diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00555">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00528">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029001">
        <property type="entry name" value="ITPase-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003697">
        <property type="entry name" value="Maf-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43213">
        <property type="entry name" value="PTHR43213"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02545">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006305">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52972">
        <property type="entry name" value="SSF52972"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00172">
        <property type="entry name" value="maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 3" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="70"/>
        </location>
    </feature>
    <feature type="site" description="Important for substrate specificity" evidence="3">
        <location>
            <position position="13"/>
        </location>
    </feature>
    <feature type="site" description="Important for substrate specificity" evidence="3">
        <location>
            <position position="71"/>
        </location>
    </feature>
    <feature type="site" description="Important for substrate specificity" evidence="3">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ40651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="198" mass="22055" checksum="5FB1DDB02BF56C57" modified="2010-01-19" version="1">MPQPLLLASTSTYRQALLKKFGYPFEVASPNIDETAQENETAQQLVLRLAQEKAKACAKDYPTHLIIGSDQVCVIDGKIIGKPLTEEKACQQLKQASGQTITFYTGLALYNAQSGECHSLCEPFHVHFRELTDEEIQHYVRREQPLYCAGSFMCEGLGIALFERLEGRDPNTLVGLPLIALRELLAKEGIDILTSQSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>D0YXY9</accession>
    <name>D0YXY9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein ImpJ/VasE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002152</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299550.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002152"/>
    <dbReference type="EnsemblBacteria" id="EEZ41120">
        <property type="protein sequence ID" value="EEZ41120"/>
        <property type="gene ID" value="VDA_002152"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3522">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="496911at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010263">
        <property type="entry name" value="T6SS_TssK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35566">
        <property type="entry name" value="PTHR35566"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05936">
        <property type="entry name" value="T6SS_VasE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03353">
        <property type="entry name" value="VI_chp_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="444" mass="50260" checksum="9956572221867A70" modified="2010-01-19" version="1">MSSRNRVVWNEGLFVKPQHFQQQQRYLEYLIDERVKSANPYLYGVTEIVLNLEYLSFGRIAIEKAKGVMPDGTVFNIPQEDTLPDALDIVDSSLANQVIYLAIPLRSESIVEVSWPDSVGATRYKAERYEARDIHSFQGDSSVIDVSPARLKLMLEKEDRSAYASIAIAKILEKRPDGSVMLDESFMPCHLNVKAVPKLQRFMGEMAGLMRERARNIAQRIGSPSQGGVADVADFMLLQALNTMQPRLHHMAHLKGIHPERLYEDLTSICGELATFTDEGRMAPEFSSYDHDRPNNSFVPVMNMLRQALSIVLEPRAVSIQLHKRKYGLMVAPIQDPNLILEGDFILAVRARMPLEELRKLFMQQTKVASVEKIRELISLQLPGIPLSPLPVAPRQLPYHAGYTYFQLDKSSQAWNMVTNSSGFAFHVAGDFPDIELQFWAIRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY17</accession>
    <name>D0YY17_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pseudouridine synthase</fullName>
            <ecNumber evidence="3">5.4.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_002180</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pseudouridine synthase RsuA family.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299599.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002180"/>
    <dbReference type="EnsemblBacteria" id="EEZ41148">
        <property type="protein sequence ID" value="EEZ41148"/>
        <property type="gene ID" value="VDA_002180"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1187">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1037615at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120159">
        <property type="term" value="F:rRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1560">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042092">
        <property type="entry name" value="PsdUridine_s_RsuA/RluB/E/F_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000748">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB/E/F"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018496">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00093">
        <property type="entry name" value="TIGR00093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01149">
        <property type="entry name" value="PSI_RSU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S4" evidence="4">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="232" mass="26251" checksum="658FAFE2CA7C4873" modified="2010-01-19" version="1">MRLDKFLCTTLGITRKEAGKILKDKLVEVNGEIVKNGALKVTDDCDVEFSGRTLSLQGPRYYMLNKPSGYVCSHVDDFNPTVFILFDEVAPERMHVAGRLDGDTTGLVLVTDDGQWSHRITSPRHVCEKTYYVETADPIEESYIQAFEEGVQLRGEKELTLPAKLEILEEKVALLTITEGKYHQVKRMFAAMGNKVELLHRERVGAIELDDDLEPGEYRPLTEDEIASVFKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY38</accession>
    <name>D0YY38_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002201</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299638.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41169">
        <property type="protein sequence ID" value="EEZ41169"/>
        <property type="gene ID" value="VDA_002201"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5032QXD">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="816124at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="285" mass="32034" checksum="0CCD9F3E810C6328" modified="2010-01-19" version="1">MSLVQIHFDGDIAVNHQVSMRTLGKTLTHLQNSMDRAYLEYHYGHLWKFATMRQDFYPAVELLVQEPREGGYVLDFLSSNSVTKAVINRVSSAVNGAVEASKQAGLDKATKIEDSLSTRIAQVESGIIVPKDLQTMIDNPDASVIRRYGDRAITREIDQILSIIRARYAGDSTFELLLSGDSSAKYEFNKESAGRFHSTVSRKELGEPVLYTAIISSLDRHNHNGKIYNLITKKVANIHFFNEVFLEMAIPFFQDKKEMVFVGSPLIEYGAFDPNAGDIYFIKLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>D0YY60</accession>
    <name>D0YY60_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Periplasmic hemin-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002223</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002223"/>
    <dbReference type="EnsemblBacteria" id="EEZ41191">
        <property type="protein sequence ID" value="EEZ41191"/>
        <property type="gene ID" value="VDA_002223"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4558">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002491">
        <property type="entry name" value="ABC_transptr_periplasmic_BD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01497">
        <property type="entry name" value="Peripla_BP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50983">
        <property type="entry name" value="FE_B12_PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019838" evidence="1">
        <location>
            <begin position="29"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="Fe/B12 periplasmic-binding" evidence="2">
        <location>
            <begin position="34"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="298" mass="31759" checksum="EF9E6D6E6095DD33" modified="2010-01-19" version="1">MSLTKPAPVFKTVSLAIAILFGATSAYAQNNDSRIISAGSAITEIINALDASDQLVAVDSTSQTLVDTKMPKVGYHRQLSAENLMSLTPTRIIGSNEMGPESTLTILKQAGVAVDIVNSGNTVSDLSKRIEQVAQLTGHQKQANELEQTVQHTVQTLTEHRSQLKNQPDFKEKKVLFVMIHDGRPVNVAGKGTTADTVINLAGAINPAAAFVENYKPISTEAMLQMQPDIILLSSRTAATIKTMPDLIKKIPVLAQTPAAQNNALAVIDGTALIGGLGIHSLNEAARLSNVFYPTVNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYB7</accession>
    <name>D0YYB7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299779.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002280"/>
    <dbReference type="EnsemblBacteria" id="EEZ41248">
        <property type="protein sequence ID" value="EEZ41248"/>
        <property type="gene ID" value="VDA_002280"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0500">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0789">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1664438at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13411">
        <property type="entry name" value="MerR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00040">
        <property type="entry name" value="HTHMERR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH merR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="390" mass="44635" checksum="412781087386E1C7" modified="2010-01-19" version="1">MYLISELATLIGVSRTTLLYYEKIGLIKGSRMSNGYRRYSEQDAQRLLLIQQLQAGGLTLKECQACLEAKLNRQVLLDRLSQLDQEIEHKTKARTLLSGLLGERSQKEWHQSLQQVAPDAHFNWLLKQGFTEKEALRLKWLSKDMNEHDVYMNDFMTVFETLERWGPGDECETRKAFSLIPSKKQAILEIGSGKGLSTLLLSELSSGNITAVDNEPMAINQLSEKVKAHNLQDRIQLVCASMTALPFAAKSFDLIWAEGCAYIMGVENALKQWKPLLQDDGILVVSDLVWLTDSPSEAHKSFWLSEYPDIQTVPTRLEQCQNLGYQVLDHFSISQQSWQNYWQPLQKRVAELLPTMPESQALKDITKEIDIYENHLGDEFGYEFFVLKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYC9</accession>
    <name>D0YYC9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lysophospholipid transporter LplT/2-acylglycerophosphoethanolamine acyltransferase/acyl-[acyl-carrier-protein] synthetase</fullName>
            <ecNumber evidence="3">2.3.1.40</ecNumber>
            <ecNumber evidence="3">6.2.1.20</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002292</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.3.1.40" evidence="3"/>
    <dbReference type="EC" id="6.2.1.20" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299802.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002292"/>
    <dbReference type="EnsemblBacteria" id="EEZ41260">
        <property type="protein sequence ID" value="EEZ41260"/>
        <property type="gene ID" value="VDA_002292"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0204">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="961884at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008779">
        <property type="term" value="F:acyl-[acyl-carrier-protein]-phospholipid O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008922">
        <property type="term" value="F:long-chain fatty acid [acyl-carrier-protein] ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="143"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="172"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="226"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="262"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="293"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="337"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="376"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="399"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="domain" description="PlsC" evidence="2">
        <location>
            <begin position="452"/>
            <end position="568"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="633" mass="70124" checksum="67FDA83CB7BC7580" modified="2010-01-19" version="1">MSQFSLMKKRHFLPYFLTQALGAFNDNLFKNILLLFVVFSALYSQQHSTMLVNVAAGLFILPFFLLSPIGGQLADKYEKSRLIRIIKACEIVIMTFAAGALWLQSVPAMLLALFLTGAQSAFFGPVKFALLPQHLSEKEIVGGNALVEMGTFIAILGGTLYAGYLFEYSHNVALVAGGSVVILSILGYLSSRAIPYAAANNPNLVINWNPITQVTKTYKAAKANRTVFLSILAISWFWFLGATYLTQLPNFSKLFISAEPKYVSLLLTLFSIGIALGSLACEKLSNHHIELGIIPIGALGISIFGIEFYFAAQHIAISDSMTVWGFITNNLRLVMDLILISAFSAIYVVPLNALIQERSDKESRAQVIAANNVMNAFFMVFSAAVSILMLSVFKLSIPQFLLVVAVVNIFVTLYVFAQVQEFLVRFVVWVVTHIMYRIKVKGTENIPSEGAAVLVCNHVSYVDALLIAATCNRPVRFVMDKDIANMPVMKYFFRWAKTIPICAAGKSPSIYKKAFKTIAEDLEAGEIVCIFPEGKLTWSGELNEFRRGIERIIEQTPVPVIPMGLKGVWGSFFSHEGGRAFTTRPKRFWSKLEVVVDKPVAPQHVSAPMLQEIVQELVYGQPSLQQDMLSTPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYD4</accession>
    <name>D0YYD4_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">8-amino-7-oxononanoate synthase</fullName>
            <shortName evidence="6">AONS</shortName>
            <ecNumber evidence="6">2.3.1.47</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">7-keto-8-amino-pelargonic acid synthase</fullName>
            <shortName evidence="6">7-KAP synthase</shortName>
            <shortName evidence="6">KAPA synthase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">8-amino-7-ketopelargonate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">bioF</name>
        <name evidence="9" type="ORF">VDA_002297</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>6-carboxyhexanoyl-[ACP] + H(+) + L-alanine = (8S)-8-amino-7-oxononanoate + CO2 + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:42288"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9955"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78846"/>
            <dbReference type="ChEBI" id="CHEBI:149468"/>
            <dbReference type="EC" id="2.3.1.47"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6 7">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 6">Cofactor biosynthesis; biotin biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 6">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.47" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002297"/>
    <dbReference type="EnsemblBacteria" id="EEZ41265">
        <property type="protein sequence ID" value="EEZ41265"/>
        <property type="gene ID" value="VDA_002297"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0156">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="479874at2"/>
    <dbReference type="UniPathway" id="UPA00078"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008710">
        <property type="term" value="F:8-amino-7-oxononanoate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009102">
        <property type="term" value="P:biotin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01693">
        <property type="entry name" value="BioF_aminotrans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001917">
        <property type="entry name" value="Aminotrans_II_pyridoxalP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004723">
        <property type="entry name" value="AONS_Archaea/Proteobacteria"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022834">
        <property type="entry name" value="AONS_Proteobacteria"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00858">
        <property type="entry name" value="bioF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00599">
        <property type="entry name" value="AA_TRANSFER_CLASS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4 6" id="KW-0093">Biotin biosynthesis</keyword>
    <keyword evidence="6 7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="8">
        <location>
            <begin position="55"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="6">
        <location>
            <begin position="122"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="28"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="221"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="247"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="363"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="6 7">
        <location>
            <position position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR604723-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="397" mass="43838" checksum="76B2334F04383507" modified="2010-01-19" version="1">MMHQFNPHSFDSRIQHALQYQQEKQLYRQRQVINRGYQQGHDIASVIHKNSQQALVNFSSNDYLGLACEPSLVKAWQQGLELYGCGSGASPLVTGQHTPHAKLEHHLATWLGFERALLFSSGYSANQAVLLSLLTRDDCLIQDKLNHASLMEAGMLSPATMKRFRHNDLSALQGLLEKNSGLSKLVVTEGAFSMDGDLAPLAEIHALCQQHHSWLMVDDAHGCGVLGEYGRGSCDIAQITPDILIVTFGKAFGMQGAAVLCSDNIAEFLIQKARHYIYSTAMPPAQAYALLHACQLIEHQGWRREKLLQLSQCFSQHLGSNVIHPVTPTPIKPIIIGDSERALDISQQLKQRGFLVSAIRPPTVAVNSARLRVTLTAAHTTEQVIELANAINEVMDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYH7</accession>
    <name>D0YYH7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002340</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005299921.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002340"/>
    <dbReference type="EnsemblBacteria" id="EEZ41308">
        <property type="protein sequence ID" value="EEZ41308"/>
        <property type="gene ID" value="VDA_002340"/>
    </dbReference>
    <dbReference type="GeneID" id="57341465"/>
    <dbReference type="eggNOG" id="COG0697">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1515911at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="180"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="212"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="242"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="266"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="13"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="155"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="300" mass="33158" checksum="714D17314525EBCD" modified="2010-01-19" version="1">MNFFHNLRDEQKGRFITLIGVMILSFDTLLVRLINCDEWTLIFWRGFLPGVVLFTVQWVMDPSVIRQHLFRLSPLNLITSILFSASTICFVFSLDHTQVASTLVITNTAPLLTAILGYFFLKEKLQKSTLIAIAIAVGGIWLVFGFKPSASEIEGDSLALVSALSMSVYLVTLRKTKGQYGSIFLIQAAVLTSIISLAAGAHPLSLDTHQNIYIFLLGGIVIPFSFLLIAKGPKYLPAAETSLILLLEVLFGPLLVWLIVGEAPTLNVAIGSAIVLITLATLTIWQWRQEMKAYLNSDKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYM6</accession>
    <name>D0YYM6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">YrdC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002389</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002389"/>
    <dbReference type="EnsemblBacteria" id="EEZ41357">
        <property type="protein sequence ID" value="EEZ41357"/>
        <property type="gene ID" value="VDA_002389"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0009">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017945">
        <property type="entry name" value="DHBP_synth_RibB-like_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006070">
        <property type="entry name" value="YrdC-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01300">
        <property type="entry name" value="Sua5_yciO_yrdC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55821">
        <property type="entry name" value="SSF55821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00057">
        <property type="entry name" value="TIGR00057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51163">
        <property type="entry name" value="YRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YrdC-like" evidence="1">
        <location>
            <begin position="28"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="221" mass="24650" checksum="FCF1939A94759A65" modified="2010-01-19" version="1">MLSNLTSNLVIGGNMSQFFYVHPENPQTRLINQAVEIIRNGGVIVYPTDSGYALGCQLENKSALERICQIRRLNDKHNFTLLCRDLSEISLYARVDNAAFRLLRNNTPGAYTFIFKGTKDVPRRLMNPKRKTIGIRVPDNQIALDLLAALGEPMMSTSLILPNHEMTESDPDEIRDKLEHAVDLIIHGGYLGEQPTTVIDFSNDDIEIVRVGAGDPAPFEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYN5</accession>
    <name>D0YYN5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative acyl-CoA hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_002398</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the acyl coenzyme A hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002398"/>
    <dbReference type="EnsemblBacteria" id="EEZ41366">
        <property type="protein sequence ID" value="EEZ41366"/>
        <property type="gene ID" value="VDA_002398"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1607">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016790">
        <property type="term" value="F:thiolester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040170">
        <property type="entry name" value="Cytosol_ACT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033120">
        <property type="entry name" value="HOTDOG_ACOT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11049">
        <property type="entry name" value="PTHR11049"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51770">
        <property type="entry name" value="HOTDOG_ACOT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HotDog ACOT-type" evidence="4">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="98" mass="10561" checksum="CA44449FAE3DAA9B" modified="2010-01-19" version="1">MSQLDLAGAILAKEISGGRVVTVSVESIEFKAPVGVGDVVCCYGECKRIGNTSMSVALEVWVKPVAQEEVGERYRVCQATFNYVAINSEGRPRPIKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0YYR4</accession>
    <name>D0YYR4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hypothetical 2-component transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_002427</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300072.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002427"/>
    <dbReference type="EnsemblBacteria" id="EEZ41395">
        <property type="protein sequence ID" value="EEZ41395"/>
        <property type="gene ID" value="VDA_002427"/>
    </dbReference>
    <dbReference type="GeneID" id="57341362"/>
    <dbReference type="eggNOG" id="COG3279">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1958442at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007492">
        <property type="entry name" value="LytTR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04397">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00850">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50930">
        <property type="entry name" value="HTH_LYTTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="3"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="HTH LytTR-type" evidence="3">
        <location>
            <begin position="134"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="239" mass="27644" checksum="858C0A7B67E780A9" modified="2010-01-19" version="1">MLKALIVEDEYLAREELQYLISTHSQIDVVASFDDGLEAFKYLQSHKVDIVFLDINIPSIDGMLLARNIHQFQHKPHIVFTTAYKEYAVDAFELEAFDYLLKPISETRVKGLLQKLESINNDIPVANEKVTTSLNLTRDNRIYVTPIKDIYYAVAKEKITEVCTASGLYIVPYTISDLMTRLPQDQFYRSHRSYIVNTSKICEIIPWVNSTYLLKLRDVEGEIPVSRSNIKTFRQLMNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ63</accession>
    <name>D0YZ63_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Heme exporter protein C</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Cytochrome c-type biogenesis protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ccmC</name>
        <name evidence="10" type="ORF">VDA_002576</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell inner membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the CcmC/CycZ/HelC family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300377.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002576"/>
    <dbReference type="EnsemblBacteria" id="EEZ41544">
        <property type="protein sequence ID" value="EEZ41544"/>
        <property type="gene ID" value="VDA_002576"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0755">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="955123at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015232">
        <property type="term" value="F:heme transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002541">
        <property type="entry name" value="Cyt_c_assembly"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003557">
        <property type="entry name" value="Cyt_c_biogenesis_CcmC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045062">
        <property type="entry name" value="Cyt_c_biogenesis_CcsA/CcmC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30071">
        <property type="entry name" value="PTHR30071"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01578">
        <property type="entry name" value="Cytochrom_C_asm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01386">
        <property type="entry name" value="CCMCBIOGNSIS"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01191">
        <property type="entry name" value="ccmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0201">Cytochrome c-type biogenesis</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="63"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="91"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="133"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="161"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="201"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrom_C_asm" evidence="9">
        <location>
            <begin position="29"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ41544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="243" mass="27672" checksum="996013BF001FECE8" modified="2010-01-19" version="1">MWKWLHPYAKPERCYQLCGTLLPWFSVLAFSLILVGTIWGLMFAPTDYQQGDSFRLIYWHVPAAIWSMGAYVSMAIAAFIGLVWQIRLSDMAAAAMAPVGAVFTFIALFTGAVWGKPMWGTWWVWDARLTSELILLFLYLGVIALYNAFDDHKTAAKAAGLLAIVGVINIPIIHFSVEWWNTLHQGATITKFAKPSMSTDMLWPLLLNIFGYAFFFCVVTMISLRNEILLRESHRPWVRELVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZ84</accession>
    <name>D0YZ84_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Flagellum-specific ATP synthase FliI</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_002597</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300432.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002597"/>
    <dbReference type="EnsemblBacteria" id="EEZ41565">
        <property type="protein sequence ID" value="EEZ41565"/>
        <property type="gene ID" value="VDA_002597"/>
    </dbReference>
    <dbReference type="GeneID" id="57341157"/>
    <dbReference type="eggNOG" id="COG1157">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="875807at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030257">
        <property type="term" value="C:type III protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044780">
        <property type="term" value="P:bacterial-type flagellum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030254">
        <property type="term" value="P:protein secretion by the type III secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005714">
        <property type="entry name" value="ATPase_T3SS_FliI/YscN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020005">
        <property type="entry name" value="FliI_clade1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040627">
        <property type="entry name" value="T3SS_ATPase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18269">
        <property type="entry name" value="T3SS_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03496">
        <property type="entry name" value="FliI_clade1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01026">
        <property type="entry name" value="fliI_yscN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AAA" evidence="4">
        <location>
            <begin position="157"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ41565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="437" mass="46536" checksum="76A6629E1883C099" modified="2010-01-19" version="1">MTLAQELAKFTTQGLACRPVASGRLTRVVGLTLEAVGCRAPVGSLCKVETVNGELEAEVIGFSGDTLFLMPSEQLTGVMPSAKVTPILQESGLPVGPELLGRVIDGVGNPLDGLGDIYTQHRASFSAPAINPLKRKPIKEPLDVGLKAINGCLTVGKGQRIGLFAGSGVGKSVTLGMMTRGTTAQVVVVGLIGERGREVKEFIDEILGEEGRQRSVVVAAPADASPLMRLKGCQTALTIAEYFRDQGQDVLLLMDSLTRFAQAQREIALSVGEPPATKGYPPSVFAKLPALVERAGNGDENQGSITAFFTVLSEGDDLQDPIADASRAILDGHIVLSREMADAGHYPAIDVERSVSRVMPAIVTEEHMIMAKAVRQILSICRKNQDLVAIGAYKPGTDPNIDQAFSLKPRLDGFLQQGMKESVPYEMCVNMLRSTLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZC1</accession>
    <name>D0YZC1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 11">Cysteine synthase</fullName>
            <ecNumber evidence="5 11">2.5.1.47</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">VDA_002634</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>hydrogen sulfide + O-acetyl-L-serine = acetate + L-cysteine</text>
            <dbReference type="Rhea" id="RHEA:14829"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:58340"/>
            <dbReference type="EC" id="2.5.1.47"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 9 11">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-cysteine biosynthesis; L-cysteine from L-serine: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the cysteine synthase/cystathionine beta-synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.47" evidence="5 11"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300553.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002634"/>
    <dbReference type="EnsemblBacteria" id="EEZ41602">
        <property type="protein sequence ID" value="EEZ41602"/>
        <property type="gene ID" value="VDA_002634"/>
    </dbReference>
    <dbReference type="GeneID" id="57341110"/>
    <dbReference type="eggNOG" id="COG0031">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1033353at2"/>
    <dbReference type="UniPathway" id="UPA00136">
        <property type="reaction ID" value="UER00200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004124">
        <property type="term" value="F:cysteine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005856">
        <property type="entry name" value="Cys_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005859">
        <property type="entry name" value="CysK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001216">
        <property type="entry name" value="P-phosphate_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01139">
        <property type="entry name" value="cysK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01136">
        <property type="entry name" value="cysKM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00901">
        <property type="entry name" value="CYS_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8 11" id="KW-0198">Cysteine biosynthesis</keyword>
    <keyword evidence="7 9 11" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PALP" evidence="12">
        <location>
            <begin position="10"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="9">
        <location>
            <begin position="177"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="272"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="10">
        <location>
            <position position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR605856-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR605856-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ41602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="322" mass="34291" checksum="858A0C8CC7E62E37" modified="2010-01-19" version="1">MSKIYEDNSLTIGNTPLVRLNRVSNGKVLAKIEARNPSFSVKCRIGANMIWDAERKGLLKEGVELVEPTSGNTGIALAFVAAARGYKLTLTMPESMSLERRKLLKALGANLELTEAAKGMKGAIEKAEEIVASNPSKYLLLQQFNNPANPEIHEKTTGPEIWDATGGDIDVFVSGVGTGGTLTGVSRYIKQQKGKAITTVAVEPAESPVITQTLNGDTVQPAPHKIQGIGAGFIPGNLDLDLIDEVERVSSDDAIEMAQRLMAEEGILAGISSGAAVVAANNLASRPEYADKNIVVILPSSGERYLSTALFAGVFTEKETRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZC6</accession>
    <name>D0YZC6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002639</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41607">
        <property type="protein sequence ID" value="EEZ41607"/>
        <property type="gene ID" value="VDA_002639"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031N6I">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="67" mass="7333" checksum="82EF76A9000D589C" modified="2010-01-19" version="1">MGSAELLEVSADEVKIAFKIRERLDDGGWRTIISPTISTGLNGPTSFECIDDALHEQVKLQVEVMTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZE8</accession>
    <name>D0YZE8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Na(+)-translocating NADH-quinone reductase subunit A</fullName>
            <shortName evidence="2">Na(+)-NQR subunit A</shortName>
            <shortName evidence="2">Na(+)-translocating NQR subunit A</shortName>
            <ecNumber evidence="2">7.2.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">NQR complex subunit A</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">NQR-1 subunit A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">nqrA</name>
        <name evidence="4" type="ORF">VDA_002661</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a ubiquinone + H(+) + n Na(+)(in) + NADH = a ubiquinol + n Na(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:47748"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="7.2.1.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NqrA family.</text>
    </comment>
    <dbReference type="EC" id="7.2.1.1" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002661"/>
    <dbReference type="EnsemblBacteria" id="EEZ41629">
        <property type="protein sequence ID" value="EEZ41629"/>
        <property type="gene ID" value="VDA_002661"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1726">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016655">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00425">
        <property type="entry name" value="NqrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008703">
        <property type="entry name" value="NqrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022615">
        <property type="entry name" value="NqrA_C_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37839">
        <property type="entry name" value="PTHR37839"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05896">
        <property type="entry name" value="NQRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11973">
        <property type="entry name" value="NQRA_SLBB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01936">
        <property type="entry name" value="nqrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0406">Ion transport</keyword>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0915">Sodium</keyword>
    <keyword evidence="2" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="2" id="KW-1278">Translocase</keyword>
    <keyword evidence="1 2" id="KW-0813">Transport</keyword>
    <keyword evidence="2" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="NQRA_SLBB" evidence="3">
        <location>
            <begin position="225"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF11973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="410" mass="44816" checksum="78A716271D6970AA" modified="2010-01-19" version="1">MGMRPTMHTRVGDVVKKGQVLFEDKKNPGVKFTAPAAGKVAEINRGAKRVLQSVVIEVEGDEQITFNRYEADQLAQLDRSAIVDQLVESGLWTALRTRPFSKVPAIDSETKAIFVTAMDTNPLAANPEMIIQEQADAFVAGLTVLSRLTGDKVHVCKSGASLPRCTQANVEEHVFAGPHPAGLPGTHIHTLFGADVNNIAWYINYQDVIAFGKLFLTGELFTDRVVAIAGPAVNKPRLVRTQIGASIEQLTDSELMPGELRVLSGSVLNGVKAEGPHAFLGRYHLQVSALREGYEKEFLGWIVPGKNKFSVTRTFLSQFFKGQLFNMTTTTNGSERAMVPIGNYEKVMPLDIEPTLLLRDLCAGDSDSAQLLGALELDEEDLALCTFVCPGKYEFGPLLRNCLDKIEKEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZL2</accession>
    <name>D0YZL2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative transcriptional regulator LysR family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_002725</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300827.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002725"/>
    <dbReference type="EnsemblBacteria" id="EEZ41693">
        <property type="protein sequence ID" value="EEZ41693"/>
        <property type="gene ID" value="VDA_002725"/>
    </dbReference>
    <dbReference type="GeneID" id="57341002"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="990666at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="5"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="298" mass="33092" checksum="43444270094A96D0" modified="2010-01-19" version="1">MNKFPSLKQLHYLVTLSETRHFGEAAKKCFVSQSTLSSGIQNLEELLDCQLIERDNKSLVFTATGDQVVTRARELLARSQDLVELSSCRGDAMEGQLRIGCIPTIAPFLLCDLVQEVNRLHPNLHLLLREDTTTNLLAALRSGEMDVLILALPVEINGMHSKVVGRDAFKMVISKQQANSVTVPLRYADLPDESVFLLEKEHCLTDHAVSACKLTTKEKINPFTATSLHTLVQMVANGLGTTFIPQMAIEHGILDNQNLVVLEPPGQEAYREIGLVWRPTSSRTHVFNQLAEIVSDLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZM3</accession>
    <name>D0YZM3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphate regulon sensor protein PhoR</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_002736</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300860.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002736"/>
    <dbReference type="EnsemblBacteria" id="EEZ41704">
        <property type="protein sequence ID" value="EEZ41704"/>
        <property type="gene ID" value="VDA_002736"/>
    </dbReference>
    <dbReference type="GeneID" id="57340990"/>
    <dbReference type="eggNOG" id="COG5002">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1827824at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004721">
        <property type="term" value="F:phosphoprotein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021766">
        <property type="entry name" value="PhoR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014310">
        <property type="entry name" value="Sig_transdc_His_kinase_PhoR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11808">
        <property type="entry name" value="PhoR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02966">
        <property type="entry name" value="phoR_proteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="8">
        <location>
            <begin position="212"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ41704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="436" mass="50276" checksum="CA1BC15A73EBA80E" modified="2010-01-19" version="1">MVERLSWKKLVWELVLFYLPWIVLGMIFGYLPWFLLIATWIQLIWHFHNQLKMSNWLWNERSLTPPTSTGSWEPLFNGIYRLQQRNRRRRRELATLIRRFRNGAESLPDAVVVFRSEGNIVWCNKLAQNLLGFRWPDDAGQPINNLLRSPDFGRYLAHQQFEHPIEITSPMNYDRTLELRIVRYTEGEYLMVVRDVSQLKQLEGMRRNFFANVSHELRTPMTVLQGYLEMSSDPDMLVGPMWTRAHGVMTEQLSRMNALVEQLLTLSKIEAAPTIDLEEVVDVPKMLDLLEKEAQSLSGDKNQQIHFEIDRSLKVHGDEDQLRSAISNLVYNAVKHTPENAAITVRWYNTKTGAKLEVTDSGEGIAPQHIHRLTERFYRVDKARSRETGGSGLGLAIVKHALSHHDTHLDIASEVGVGSTFSFVLPNRLVAQAEVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZM6</accession>
    <name>D0YZM6_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Nuclease SbcCD subunit D</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">sbcD</name>
        <name evidence="10" type="ORF">VDA_002739</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'-&gt;5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 7">Heterodimer of SbcC and SbcD.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the SbcD family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300872.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002739"/>
    <dbReference type="EnsemblBacteria" id="EEZ41707">
        <property type="protein sequence ID" value="EEZ41707"/>
        <property type="gene ID" value="VDA_002739"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0420">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1831911at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00840">
        <property type="entry name" value="MPP_Mre11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041796">
        <property type="entry name" value="Mre11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004593">
        <property type="entry name" value="SbcD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026843">
        <property type="entry name" value="SbcD_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12320">
        <property type="entry name" value="SbcD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00619">
        <property type="entry name" value="sbcd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="7" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6 7 10" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 7" id="KW-0540">Nuclease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="8">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="SbcD_C" evidence="9">
        <location>
            <begin position="287"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ41707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="413" mass="46551" checksum="17E15CC7F10C4B59" modified="2010-01-19" version="1">MKIIHTSDWHLGHQLHGYNREYEHQAFLDWLADELETQQADALLVAGDIFDTANPPASSWRMLYRFLAKISKTLPSLDVVMIGGNHDSPSKLDAPHELLKAFDLHMVGGIHRLEDGSLDVERMLVPITNKEQQIAAYVLAVPFLRSADLRTDNLDENDDRLIKGVEVLYGEMTQAARKLLTPEQAMIGMGHAYMASGQLSEMSERRVLGGNQHALPASIFADDMSYVALGHLHLAQKVAKKEHVRYSGSPIPLSMSERNYKHQILAVELDGNEVTAIDEINIPRNVDMLKVPAKPAPLDEVLAALKSLPDDELPREQQPFLEVHVLLDKPQALLREKVLQALEGKAVRLAKITPHYNQREQQDSLQHRRLSDVSPQQVFALSWNKKFDGEPTEAMVEAFETLLTQVEEQDEER</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZR1</accession>
    <name>D0YZR1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NAD kinase</fullName>
            <ecNumber evidence="5">2.7.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">ATP-dependent NAD kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">nadK</name>
        <name evidence="6" type="ORF">VDA_002774</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + NAD(+) = ADP + H(+) + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:18629"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the NAD kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.23" evidence="5"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300967.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002774"/>
    <dbReference type="EnsemblBacteria" id="EEZ41742">
        <property type="protein sequence ID" value="EEZ41742"/>
        <property type="gene ID" value="VDA_002774"/>
    </dbReference>
    <dbReference type="GeneID" id="57340949"/>
    <dbReference type="eggNOG" id="COG0061">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1463423at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003951">
        <property type="term" value="F:NAD+ kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019674">
        <property type="term" value="P:NAD metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006741">
        <property type="term" value="P:NADP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00361">
        <property type="entry name" value="NAD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017437">
        <property type="entry name" value="ATP-NAD_kinase_PpnK-typ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002504">
        <property type="entry name" value="NADK"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01513">
        <property type="entry name" value="NAD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="SSF111331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 5" id="KW-0520">NAD</keyword>
    <keyword evidence="3 5" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5 6" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="73"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="73"/>
            <end position="74"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="147"/>
            <end position="148"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="188"/>
            <end position="193"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="248"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="293" mass="32223" checksum="3985024E7B73DF00" modified="2010-01-19" version="1">MKRIFDTIALIGKPRNPEALQTHLNLYSWLTEQGYNVLVDQRLTGDLDIPADCFCDLLTIGDLANLAIVIGGDGNMLGAARVLSRFDISVIGVNRGNLGFLTDLDPDEFQQQLGAVLAGEFVTEHRFLLEAEVHRHGQIKSRNAALNEAVLHPDKIAHMIEFEVYIDERFAFSQRSDGLIIATPTGSTAYSLSGGGPILSPSLNAITLVPMFPHTLSCRPIVVDGNHRIKLMVSPENGSTLEVSCDGQVSLPVSPGDEIHIYQSPEQLQLIHPKSYSYYNVLRSKLGWSSKLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZR8</accession>
    <name>D0YZR8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002781</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300988.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ41749">
        <property type="protein sequence ID" value="EEZ41749"/>
        <property type="gene ID" value="VDA_002781"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502ZFTM">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="572409at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="482" mass="54755" checksum="4B37A80E7FB14771" modified="2010-01-19" version="1">MKLGFFFGAGAEVGYGLPIGGKFAIDLFRQDVSEHKQALRDHLRSLDKYDPYVTGWLPEKYATQRIHAFGKNEFTSLIESSIEYRKSEIVRRLNNFDIEADKALADLGIDKQAAIDKFNEEMDHAFGDQLFSTAVQINSLLADEVKLFGSEMYSAMLSILRSKDNTADLQRYAGAFLQLLVGAHGQELVQRLNQELFEAAPDDIPIFDDVSGMFKVEFSQAGLSALELLMESKREYDVENGSTCDLLSALAQQLLENIFTTVLDYQSLIDSHFRYLYSPKTEWAKFSKMVIFLWATRKYIKDQLDHVGKLPDNGYYHDLKRCEELGIEISAIGTANYNNLVEAIAEQLDYQIPNVHHLNGGVCDYYNPYKNSVVSCQHVEDIPKDQIYVPFILTQSGLKPLTSVDMSRRYVSLFDRYSECDAIVVIGYGFNIDDSHINGLFRQLIEDNNKSLYWICLNTDGTAETQKRTLVQKLRISAANRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZS0</accession>
    <name>D0YZS0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AAA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_002783</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005300994.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002783"/>
    <dbReference type="EnsemblBacteria" id="EEZ41751">
        <property type="protein sequence ID" value="EEZ41751"/>
        <property type="gene ID" value="VDA_002783"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3910">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="511392at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13304">
        <property type="entry name" value="AAA_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="186"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ41751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="507" mass="56225" checksum="BBB6FA4194233B8C" modified="2010-01-19" version="1">MNIIIVPREQKVPSTGINTAYLHVDRWNDFSFVTMFFLTVFDEKGGGHDIGQVKIGFKGQTTEKSTYGTLSSLFHALPDGYFSVGQDVEYYKNIAQLSEFTREALLNGLKDIAFDSSLIELVQDEDVFRTSLLRDVSLSVIKGQFSRVLDGSSPLTDFEFKFVRPVQDKMSGIELKFSVKVGDKPTSNIHAIIGRNGVGKTTLLNGMIDAVTSKGQSVAKFYDVEGWRNNPIDTDYFSSLVSVSFSAFDPFSPPSEQPDPSKGTCYFYIGLKNGDDSLKGLNDIHEDFLHALKACLNQAPKKGRWLKAIDTLESDENFAGMGLKELAEYSGEVLTSKARKRIKKMSSGHAVVLLTITRLVATVEEKTLVLIDEPESHLHPPLLSAFVRALSDLLLDRNGVAIIATHSPVVLQEVPRRCVWKINRSGLETKPLRPSIETFGENVGILTREVFGLEVVKSGFHDLLVKSVEAGGTYESIVEDYRDQLGIEARALLKALVVNRDRSKDEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZW1</accession>
    <name>D0YZW1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ubiquinone biosynthesis accessory factor UbiT</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ubiT</name>
        <name evidence="3" type="ORF">VDA_002824</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Likely functions as an accessory factor.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the UbiT family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002824"/>
    <dbReference type="EnsemblBacteria" id="EEZ41792">
        <property type="protein sequence ID" value="EEZ41792"/>
        <property type="gene ID" value="VDA_002824"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3154">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02231">
        <property type="entry name" value="UbiT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003033">
        <property type="entry name" value="SCP2_sterol-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036527">
        <property type="entry name" value="SCP2_sterol-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016830">
        <property type="entry name" value="UbiT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02036">
        <property type="entry name" value="SCP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF025550">
        <property type="entry name" value="UCP025550_lpd_carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55718">
        <property type="entry name" value="SSF55718"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="domain" description="SCP2" evidence="2">
        <location>
            <begin position="9"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="135" mass="15612" checksum="A3E15CD004AAA70C" modified="2010-01-19" version="1">MVFKEALEDGDFEFLEDRWLKVEVRDLGLQWFISYQNEQLVVSEQVEQEDVSFSGECNDLVLIAARKEDPDTLFFQRRLRIEGDTELGLEVKNLMDSIDLESLPAPVQFVLQQSADFIYKGMHQADDAKEVVNAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZX7</accession>
    <name>D0YZX7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_002840</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301165.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002840"/>
    <dbReference type="EnsemblBacteria" id="EEZ41808">
        <property type="protein sequence ID" value="EEZ41808"/>
        <property type="gene ID" value="VDA_002840"/>
    </dbReference>
    <dbReference type="GeneID" id="57340875"/>
    <dbReference type="eggNOG" id="COG1534">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2034603at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001890">
        <property type="entry name" value="RNA-binding_CRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017924">
        <property type="entry name" value="RNA-binding_YhbY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035920">
        <property type="entry name" value="YhbY-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01985">
        <property type="entry name" value="CRS1_YhbY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01103">
        <property type="entry name" value="CRS1_YhbY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75471">
        <property type="entry name" value="SSF75471"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00253">
        <property type="entry name" value="RNA_bind_YhbY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51295">
        <property type="entry name" value="CRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="CRM" evidence="3">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="98" mass="11097" checksum="04596FD5FBBD7B5B" modified="2010-01-19" version="1">MNLSTKQKQYLKGLAHNLKPVVLMGANGLTEAVLAEIEIALDHHELIKVKVASEERETKLLIVDAIIRETKAEKVQVIGKTLVLYRQSEDRKIELPRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZX9</accession>
    <name>D0YZX9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">OmpL_phopr porin-like protein L</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_002842</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell outer membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Gram-negative porin family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301170.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002842"/>
    <dbReference type="EnsemblBacteria" id="EEZ41810">
        <property type="protein sequence ID" value="EEZ41810"/>
        <property type="gene ID" value="VDA_002842"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1064531at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015288">
        <property type="term" value="F:porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034220">
        <property type="term" value="P:ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00342">
        <property type="entry name" value="gram_neg_porins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033900">
        <property type="entry name" value="Gram_neg_porin_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001897">
        <property type="entry name" value="Porin_gammaproteobac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13609">
        <property type="entry name" value="Porin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00183">
        <property type="entry name" value="ECOLIPORIN"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003018715" evidence="4">
        <location>
            <begin position="22"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="domain" description="Porin_4" evidence="5">
        <location>
            <begin position="9"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="338" mass="36981" checksum="6FF5BC06014323C3" modified="2010-01-19" version="1">MNKNILALAVAAAAFSGAVSAAQVYSDDASTLNIGGRIEARGNGVVGHDNFNDDSRVRVNIAGQTQINDDLYGLGFFEREFKSDKSDDENRYIYAGIGSKTYGQLVYGKTDGSLGMITDFTDIMEYFGNEAGGKINAADRPEDSLAYLGQFGGLTVRANYVFDADGTDFSAPVDSSDNSGFSVGSVYNLNNGLAFGLGYGEQKQQEKNLTAKQGFASVSYTSGDFYVAGLYQNARNIGYQYGYDDAKHSNEYQGYELATAYTINKLVLRSTYNYMENMDSNDKMANALAFDGSYFFTPNFRTYAGYKVNLLDKNDVKKMGEVKQAADDQFVLGARYDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>D0YZZ1</accession>
    <name>D0YZZ1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Na(+)/H(+) antiporter NhaA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Sodium/proton antiporter NhaA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">nhaA</name>
        <name evidence="10" type="ORF">VDA_002854</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>2 H(+)(out) + Na(+)(in) = 2 H(+)(in) + Na(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:29251"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301203.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002854"/>
    <dbReference type="EnsemblBacteria" id="EEZ41822">
        <property type="protein sequence ID" value="EEZ41822"/>
        <property type="gene ID" value="VDA_002854"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3004">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1805428at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015081">
        <property type="term" value="F:sodium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006885">
        <property type="term" value="P:regulation of pH"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01844">
        <property type="entry name" value="NhaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023171">
        <property type="entry name" value="Na/H_antiporter_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004670">
        <property type="entry name" value="NhaA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30341">
        <property type="entry name" value="PTHR30341"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06965">
        <property type="entry name" value="Na_H_antiport_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00773">
        <property type="entry name" value="NhaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0050">Antiport</keyword>
    <keyword evidence="3 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0915">Sodium</keyword>
    <keyword evidence="8 9" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="42"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="146"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="173"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="201"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="252"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="285"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="325"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="360"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ41822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="390" mass="40728" checksum="E880CD35C648D08B" modified="2010-01-19" version="1">MTDAIRKFLKLESAGGIVLIIAAAVAMFIANSPLGSVYSGVLHSYVAGLSVEHWINDGLMAIFFLLIGLEVKRELIEGALNTKEKAIFPAIAAVGGMIAPALVYVAFNFSDPVALKGWAIPAATDIAFALGVMALLGNRVPVSLKVFLLALAIIDDLGVIVIIALFYSSDLSTLALAVAFASTAALFIMNAKNVTKLTPYLVVGAILWFSVLQSGVHATLAGVVLGFAIPLSGKDGDHSDNYSPLKHLEHALHPYVAFLILPLFAFANAGISLEGVSFASLTSMLPLGIAAGLFIGKPLGIFTASYIAVKTGLAKLPDDIGMKEIFAVSVLCGIGFTMSIFISSLAFVGESGDFSTYSRLGILLGSTFAALIGYGLLNRALPKTLSKAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z025</accession>
    <name>D0Z025_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Glutamate synthase [NADPH] large chain</fullName>
            <ecNumber evidence="16">1.4.1.13</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">VDA_002888</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="14">Amino-acid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glutamate synthase family.</text>
    </comment>
    <dbReference type="EC" id="1.4.1.13" evidence="16"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301275.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002888"/>
    <dbReference type="EnsemblBacteria" id="EEZ41856">
        <property type="protein sequence ID" value="EEZ41856"/>
        <property type="gene ID" value="VDA_002888"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0067">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0069">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0070">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5568at2"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051538">
        <property type="term" value="F:3 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004355">
        <property type="term" value="F:glutamate synthase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006537">
        <property type="term" value="P:glutamate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00982">
        <property type="entry name" value="gltB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02808">
        <property type="entry name" value="GltS_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002489">
        <property type="entry name" value="Glu_synth_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036485">
        <property type="entry name" value="Glu_synth_asu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006982">
        <property type="entry name" value="Glu_synth_centr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002932">
        <property type="entry name" value="Glu_synthdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00310">
        <property type="entry name" value="GATase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04898">
        <property type="entry name" value="Glu_syn_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01645">
        <property type="entry name" value="Glu_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01493">
        <property type="entry name" value="GXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69336">
        <property type="entry name" value="SSF69336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0003">3Fe-4S</keyword>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0288">FMN</keyword>
    <keyword evidence="12" id="KW-0314">Glutamate biosynthesis</keyword>
    <keyword evidence="8" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 16" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="15">
        <location>
            <begin position="21"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00029440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EEZ41856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="1515" mass="167962" checksum="A5D6F6CF0CB6A44B" modified="2010-01-19" version="1">MTDQERSTQGMYVPEMEHDACGIGFVAHLKNRKSHQIVTQALDMLARMEHRGGQGCDPCSGDGAGILLQKPHEFLLEESVKQGIKLPSFDQYGVGVVLFPKDEHKRQQCRDILERNAKRLDLEIIGYRVLPVDNSMIGEDPLSTEPQFEHVFITGGANLKPEVLERKLYVLRNYTVRVCLESVSNIGDDFYINSMSYKTLVYKGQITTEQVPQYFLDLQNPAMVTALALVHSRFSTNTFPKWRLAQPFRYIAHNGEINTVRGNLNWMKAREAILESELFSPQEISMLLPICQEGSSDSSNFDMALELLVLSGRTLPHALMMLIPEAWQENKEMDPKRRAFYQYHANVMEPWDGPASVCFTDGVQVGATLDRNGLRPSRYTVTKDDFLIMASESGVVEIEPENIQFRGRLQPGRIFVADLEQGRIISDEEVKDSIAQAQPYQEWVKNNLLSLKKLPDADNMHHQPTPERLLHHQQAFGVSSEEVDEIIVPLASTGYEPLGSMGVDWPVAVLSHQSQHLANYFKQLFAQVTNPPIDPIRERMVMSLNTYIGKDQNLLIETPQHCRKVELESPVLSNAELEKLRAIDNEHLQAKTLDIVFRASGEPGKLERALKRICQYSEDAVIDGYSIIILTDRAVNSNHAAIPAMLAVGAVHHHLIRKGLRAKCDIVVETGDARETHHFATLVGYGASAINPYLVTETIVDLQRKGKLDREKTTEELFNNYRKGVNGGLLKIFSKMGISTLQSYHGAQIFEALGISKAVVDKYFTGTVSRIEGLTLDDIAREVVVRHRVGYPTREIPIQMLDVGGVYQWKQRGEKHLFNPETISLLQQSTRNKDYQQFKQYANAVDAQGDNAVTLRSQLDFIKNPAGAIAIENVEPIESILKRFATGAMSFGSISYEAHSTLAVAMNRIGAKSNSGEGGEDPIRFEPNENGDWERSAIKQVASGRFGVTSYYLTNADELQIKMAQGAKPGEGGQLPGDKVDDWIGATRHSTPGVGLISPPPHHDIYSIEDLAQLIYDLKNANRRSRVNVKLVSEAGVGTIASGVAKAKADVVLIAGFDGGTGASPISSIRHTGLPWELGLAETHQTLLKNGLRNRIVVQADGQMKTPRDLAIATLLGAEEWGVATAALVVEGCIMMRKCHKNTCPVGIATQNKTLRERFDGRVEDVVTFFQYMAQGLREIMAELGFSTIDEMVGQVNKLKVRHNIDHWKYQNLDLSPILFNEAARADDGIYNQKQQQHNLEQVLDRQLIELAAPALYEGKAVEAELAIINTDRSTGTMLSNEISKIYKDQGLPQPLNVKFNGSAGQSFGAFLAKGVKFTVEGDANDYWGKGLSGGTLVLYPNQQSSIIAEDNIVVGNVCFYGATSGESYIRGMAGERFCVRNSGAKVVVEGIGDHGCEYMTGGIALILGQTGRNFAAGMSGGVAYVWDQYGDFDSKLNAELVDLDPLDDEDKALLLDMLTKHVAYTGSSVAELFLSNFDHNLQQIVKVMPRDYKAVLEKRKAEAENKEELEAIDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z030</accession>
    <name>D0Z030_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Adenosylcobinamide-phosphate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">VDA_002893</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="3">Cofactor biosynthesis; adenosylcobalamin biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the CobD/CbiB family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301285.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002893"/>
    <dbReference type="EnsemblBacteria" id="EEZ41861">
        <property type="protein sequence ID" value="EEZ41861"/>
        <property type="gene ID" value="VDA_002893"/>
    </dbReference>
    <dbReference type="GeneID" id="57340815"/>
    <dbReference type="eggNOG" id="COG1270">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2029688at2"/>
    <dbReference type="UniPathway" id="UPA00148"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048472">
        <property type="term" value="F:threonine-phosphate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004485">
        <property type="entry name" value="Cobalamin_biosynth_CobD/CbiB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34308">
        <property type="entry name" value="PTHR34308"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03186">
        <property type="entry name" value="CobD_Cbib"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="16"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="166"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="301"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ41861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="319" mass="35614" checksum="A6E5A138B4DEB502" modified="2010-01-19" version="1">MTSSWFDLAINNSSLLIMWGALLLHWVLPIPTAIHPLTIWQRLAVMIAEKVNHSNDSPKQQTLAGSLAWFTLWGLALIFFIALYQLVQLDSVFQLTLLWLALDWRSIDEFGQRFTQAYQQENKPLCQHLLAPWVHRNVAPLSLLGLGKAGAETLLVGYGRNVVTVLFWYCIGGGLGALLYRLASGLARAWSPTRSQFQFFGQTASKITALLDIVPMRIFSLLLCFGNNGKQALQGLQQQGENWLSPGPGWLLIASGHKLSIALGGPALYHDKKRERPRIGGRIAPAGFHLEQLLLLLRQRLLVWLLLLSITLIIFHLGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z031</accession>
    <name>D0Z031_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Vitamin B12-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">btuF</name>
        <name evidence="3" type="ORF">VDA_002894</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">The complex is composed of two ATP-binding proteins (BtuD), two transmembrane proteins (BtuC) and a solute-binding protein (BtuF).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the BtuF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301287.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002894"/>
    <dbReference type="EnsemblBacteria" id="EEZ41862">
        <property type="protein sequence ID" value="EEZ41862"/>
        <property type="gene ID" value="VDA_002894"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0614">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1473468at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015889">
        <property type="term" value="P:cobalamin transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01000">
        <property type="entry name" value="BtuF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002491">
        <property type="entry name" value="ABC_transptr_periplasmic_BD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023544">
        <property type="entry name" value="ABC_transptr_vit_B12-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01497">
        <property type="entry name" value="Peripla_BP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50983">
        <property type="entry name" value="FE_B12_PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0574">Periplasm</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5009009108" description="Vitamin B12-binding protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="Fe/B12 periplasmic-binding" evidence="2">
        <location>
            <begin position="25"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>cyanocob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:17439"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for BtuC binding" evidence="1">
        <location>
            <position position="74"/>
        </location>
    </feature>
    <feature type="site" description="Important for BtuC binding" evidence="1">
        <location>
            <position position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ41862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="277" mass="31236" checksum="62D11AC7F79EF05E" modified="2010-01-19" version="1" precursor="true">MRRFGITLLLLFSSISCWANSSVQRIISLSPHTTELAFAAGLGDKLVAVSEYSDYPARAQKLEHVANYKGIKLERILALKPDLVLAWKGGNPPREMEKLAQLGIPIFYSNPVKLEDIANNIRLLGQYADNPSQADLSATAFQNQLELLRKKYHNEKSVSYFYQLSDQPLMTVAKGGWPNQVFALCGGKNIFADSTVPYPQVNTEQVVVRQPQVIFGTSHSNTDLSRWQQWQGKIPAVDHHAIYRLNSDWLNRPTPRTLLAVQQVCDYLDQVRNSSHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z053</accession>
    <name>D0Z053_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_002916</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002916"/>
    <dbReference type="EnsemblBacteria" id="EEZ41884">
        <property type="protein sequence ID" value="EEZ41884"/>
        <property type="gene ID" value="VDA_002916"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1714">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ41884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="59" mass="6601" checksum="5637882120E26D2D" modified="2010-01-19" version="1">MKAWKLKLQNKDGSNIRIAQACIRMGTSAFGLGNLLAPFSKEKQSFQDLMAECEMIVTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z082</accession>
    <name>D0Z082_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Arylsulfatase</fullName>
            <ecNumber evidence="4">3.1.6.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_002945</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.6.1" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002945"/>
    <dbReference type="EnsemblBacteria" id="EEZ41913">
        <property type="protein sequence ID" value="EEZ41913"/>
        <property type="gene ID" value="VDA_002945"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4991">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004065">
        <property type="term" value="F:arylsulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016476">
        <property type="entry name" value="SH3_dom_pro"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006158">
        <property type="entry name" value="UCP006158_SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04211">
        <property type="entry name" value="SH3_and_anchor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="127"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="74"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ41913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="160" mass="17970" checksum="51662B73780D4D12" modified="2010-01-19" version="1">MGSIDAGSKVVLLDTNKSSGFSRVKDDKGRTGWVNSDFISTQMGLKERVPALEQELAEVKTKLAESITSNDSRNAGMKTTLDQRNQQITELEDRNSKLNEQLSTAQTEIRELRAKIDTQKDDLLMRWFMYGGMVAGVGLLLGLVLPHIIPRRRKRHNGWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-06-02" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0D2</accession>
    <name>D0Z0D2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_002995</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005301506.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_002995"/>
    <dbReference type="EnsemblBacteria" id="EEZ41963">
        <property type="protein sequence ID" value="EEZ41963"/>
        <property type="gene ID" value="VDA_002995"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2911">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="754526at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007452">
        <property type="entry name" value="TamB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04357">
        <property type="entry name" value="TamB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="181"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="184"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ41963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="1250" mass="134069" checksum="110C7627F121F738" modified="2010-01-19" version="1">MIWVKRISLAVLAILLVLVITLATLLFTPAGVKVALWGAQKALPALKIESSDGGFFDGLILNNVQYDDGNMSLLAKKISLNLDDGCLLTPEICVKELGVDGVTFAMPELPPPSTEPEQPSEPVTEISMPLPIHIENVHLNDIKLDILGNKVGWKSFTTAAELAGSKVTLKPTDWQDIDLTLAPAKPQTKSSSKAKSSAPTKAEPIVLPDVVLPMSFDVERFTVKNFELHGETPHKVSLLELIAKAEKSNINISKLELIAPQASVNAKADVTLTGDYPLELDANAKVAMKPLQGHKLSVKASGSLAKLSLDANLKGKLDALVKGQLSPLDPNLPFDVKVSSNHIQWPIDTKAEYNVNKTNIKAKGSLKGFSFSAKTDVNGTTIPTVNVDLNGKGDLNQVDLSALTIKTLGGVVSGNAKASWKNTVKWQGAIALDSIQPGKQWPEADGNISGKLETSGGLTAKGGWFAKLPLLDIHGNIMKQPFTLAGSANAEDLSGKGDLNVVTDGLTLKHGINGLTAKGSLGKDWNMIAQVNAPDLSRSLAGLRGRVMGDVKLTGKMAEPNVMIDLEGNGLGWQKMASLQSFAIKGQIKPMPELQGDLSITAANGKYDTMSLKDLKVLFNGSEKQHTLTLNLDAEPVSANLALEGQLNRETGWQGMLSKGNIKTPVGNWVLNHPTRLGYNLKTAMANVEAHCWQQGQASICLTQNLTAGKSGKADLAIKNINFEMLKPYLPDGIELKGGVGATASASWAPNQAPVVNAQVLLPEGSVNQRFSPDERPLTFAWDKVTLNADMKNDVLNANWLFAIKDNGDLSGQARITNLQGNQQINAQVKLDRFMLAFLEPVIKDYHKFDGAVNADLRVTGPILHPAVNGQLSVDKLQATGRKVPLDIKDAEITIDFNGYNAQLSGDIFTPDGKLLLRGMGDWQNMAAWKSELHVKGSELQVSVPPMVSLKVSPELSITANPKGADITGNVEIPWGRIRVNQLPKSAVSVSKDQVLLNNDLKPVKEQVSTPFDIRTNVMVKIGDDMKLKAFGLNAGLTGDLNVRQEGKGPMIYGEINITDGSFYRALGQELQIRKGQIIFNGPADQPYLAFEAIRDPDNIEDDVIAGVRVTGSADAPKVEIFSDPAMPQQNALSYILTGRNLDSEDADNGNAMTTALIGMGLAQSGQLVGDIGEAVGVKDLSLSTAGSGDDSQVQISGYIAPGLQVKYGVGIFNSIGEFTVRYRLMKDLYVEAVSGLDSAVDLLYQFEFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0D8</accession>
    <name>D0Z0D8_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sulfate permease Trk-type</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">VDA_003001</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ41969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003001"/>
    <dbReference type="EnsemblBacteria" id="EEZ41969">
        <property type="protein sequence ID" value="EEZ41969"/>
        <property type="gene ID" value="VDA_003001"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0471">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0569">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1450">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004680">
        <property type="entry name" value="Cit_transptr-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006037">
        <property type="entry name" value="RCK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036721">
        <property type="entry name" value="RCK_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001898">
        <property type="entry name" value="SLC13A/DASS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03600">
        <property type="entry name" value="CitMHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00939">
        <property type="entry name" value="Na_sulph_symp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02080">
        <property type="entry name" value="TrkA_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116726">
        <property type="entry name" value="SSF116726"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51202">
        <property type="entry name" value="RCK_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="43"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="120"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="157"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="374"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="398"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="421"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="451"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="481"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="505"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="543"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="7">
        <location>
            <begin position="185"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="7">
        <location>
            <begin position="271"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EEZ41969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="568" mass="61011" checksum="44A72281A760516E" modified="2010-01-19" version="1">MLLVLVIALVVTKIKPAWLFAGIAFIAYQSNLLSLPELAGNFTNSSLLTLVLLILISIALEKTRLISWVGLQISQGSHSKVVTKLGLSTAILSSLTNNTAVVVSLIGAVKRNQRHAPSKLLLPLSYAAILGGTLTLIGTSTNLIVNSFVENAGLPSLSFFAPSGIGLAVLVVGLFVLIPLSYSLPTYDDDHDDSLPYFLEATVASHSQLIGKSVTDNGLRALRRLFLAEIIREGRTIAPVCPDTELVANDRLLFCGDIDSVTTLQEIHGLELFGQHHLNGQSMLEMVVSHSGHLCGKTLKQTDFRERFDGVVVAIRRGHERLAGGLGNIRLEAGDTLVIVPGKTFFTNRAQLSREFVLFNGLDSSARFDQRKSALVLVSFISVIALALLNWVPLLKGLAILLVGLLAFGMISLAEIRRRFPIDIIVIVGSALSLAQLMLSTGLSQRLGDALITAFNGFGVYGGLIAVYLLTLVLTELITNNAAAALAFPIGYSLALGYGVDPMPFIMAVLFGASASFISPYGYQTNLLVYSVGNYQLRDFIKLGLPLSLVYSSTVLVLIPLFFPFSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0H5</accession>
    <name>D0Z0H5_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Epoxyqueuosine reductase</fullName>
            <ecNumber evidence="7">1.17.99.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Queuosine biosynthesis protein QueG</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">queG</name>
        <name evidence="9" type="ORF">VDA_003039</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>AH2 + epoxyqueuosine(34) in tRNA = A + H2O + queuosine(34) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:32159"/>
            <dbReference type="Rhea" id="RHEA-COMP:10345"/>
            <dbReference type="Rhea" id="RHEA-COMP:10346"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:82831"/>
            <dbReference type="ChEBI" id="CHEBI:82834"/>
            <dbReference type="EC" id="1.17.99.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="7">Binds 2 [4Fe-4S] clusters per monomer.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>cob(II)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:16304"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="7">tRNA modification; tRNA-queuosine biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the QueG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.17.99.6" evidence="7"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003039"/>
    <dbReference type="EnsemblBacteria" id="EEZ42006">
        <property type="protein sequence ID" value="EEZ42006"/>
        <property type="gene ID" value="VDA_003039"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1600">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00392"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052693">
        <property type="term" value="F:epoxyqueuosine reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:queuosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00916">
        <property type="entry name" value="QueG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004453">
        <property type="entry name" value="QueG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013542">
        <property type="entry name" value="QueG_DUF1730"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30002">
        <property type="entry name" value="PTHR30002"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08331">
        <property type="entry name" value="DUF1730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00276">
        <property type="entry name" value="TIGR00276"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7" id="KW-0846">Cobalamin</keyword>
    <keyword evidence="7" id="KW-0170">Cobalt</keyword>
    <keyword evidence="1 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7" id="KW-0408">Iron</keyword>
    <keyword evidence="6 7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 7" id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="8">
        <location>
            <begin position="202"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Cob(II)alamin binding" evidence="7">
        <location>
            <begin position="267"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="160"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>cob(II)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:16304"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>cob(II)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:16304"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>cob(II)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:16304"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>cob(II)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:16304"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>cob(II)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:16304"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="214"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
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        <location>
            <position position="217"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
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        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
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        <location>
            <position position="224"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
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        <location>
            <position position="240"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="242"/>
        </location>
        <ligand>
            <name>cob(II)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:16304"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="267"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="270"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="274"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="308"/>
        </location>
        <ligand>
            <name>tRNA</name>
            <dbReference type="ChEBI" id="CHEBI:17843"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ42006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="400" mass="45206" checksum="3C5CF00E6A1EE3E5" modified="2010-01-19" version="1">MSYPDSIYFVINFAPFSVTCDSVMTIDLNQLSLDIKQWGKELGFQQVGICDVDLSQHEAQLQRWLDAGYHGDMDWMARHGMMRARPDELHPGTVRVISVRMNYLPPEAGFAQTLKAPEKGYISRYALGRDYHKLVRNRLKQLGQKIEAVVGPFGYRPFVDSAPILERPLAQKAGLGWTGKHSLILNQDAGSWFFLGELLIDLPLPVDEALENQCGKCVACMTSCPTGAIVEEGVIDARRCISYLTIEYSGVIPEEFRPLMGNRIYGCDDCQLVCPHSRHGEITEETDYHCRPTLAQQDLLTLFSWDEKTFLKNTEGSAIRRIGHIQWLRNISIAMGNAPYQEAILIALEECLGLDETLDIHLNWAIGQQKKRRDENSITVISNKAQRLVRIIEKGLPRDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0W3</accession>
    <name>D0Z0W3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transcription termination factor Rho</fullName>
            <ecNumber evidence="8">3.6.4.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">ATP-dependent helicase Rho</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rho</name>
        <name evidence="11" type="ORF">VDA_003177</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homohexamer. The homohexamer assembles into an open ring structure.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8 9">Belongs to the Rho family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302083.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003177"/>
    <dbReference type="EnsemblBacteria" id="EEZ42144">
        <property type="protein sequence ID" value="EEZ42144"/>
        <property type="gene ID" value="VDA_003177"/>
    </dbReference>
    <dbReference type="GeneID" id="57340589"/>
    <dbReference type="eggNOG" id="COG1158">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1619125at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008186">
        <property type="term" value="F:ATP-dependent activity, acting on RNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription, termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04459">
        <property type="entry name" value="Rho_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01128">
        <property type="entry name" value="rho_factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01884">
        <property type="entry name" value="Rho"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011129">
        <property type="entry name" value="CSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041703">
        <property type="entry name" value="Rho_factor_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011112">
        <property type="entry name" value="Rho_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036269">
        <property type="entry name" value="Rho_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011113">
        <property type="entry name" value="Rho_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004665">
        <property type="entry name" value="Term_rho"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46425">
        <property type="entry name" value="PTHR46425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07498">
        <property type="entry name" value="Rho_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07497">
        <property type="entry name" value="Rho_RNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00357">
        <property type="entry name" value="CSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00959">
        <property type="entry name" value="Rho_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68912">
        <property type="entry name" value="SSF68912"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00767">
        <property type="entry name" value="rho"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51856">
        <property type="entry name" value="RHO_RNA_BD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 8" id="KW-0347">Helicase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6 8" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="1 8" id="KW-0806">Transcription termination</keyword>
    <feature type="domain" description="Rho RNA-BD" evidence="10">
        <location>
            <begin position="48"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="RNA-binding 1" evidence="8">
        <location>
            <begin position="61"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="RNA-binding 1" evidence="8">
        <location>
            <begin position="78"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="RNA-binding 1" evidence="8">
        <location>
            <begin position="108"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="RNA-binding 2" evidence="8">
        <location>
            <begin position="284"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="169"/>
            <end position="174"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="181"/>
            <end position="186"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="RNA-binding 2" evidence="8">
        <location>
            <position position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EEZ42144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="419" mass="46887" checksum="A4F7848E4933288A" modified="2010-01-19" version="1">MNLTELKKQPISNLVALGESLGLENLARLRKQDIIFSILKQHAKSGEDIFGDGVLEILQDGFGFLRSADSSYLAGPDDIYVSPSQIRRFNLRTGDTISGKIRPPKDGERYFALLKVNEVNYDKPDNARNKILFENLTPLHANERMRMERGNGSTEDITARVLDLASPIGKGQRGLIVAPPKAGKTMLLQNIAQSIAHNHPECELMVLLIDERPEEVTEMQRLVKGEVVASTFDEPASRHVQVAEMVIEKAKRLVEHKKDVVILLDSITRLARAYNTVVPSSGKVLTGGVDANALHRPKRFFGAARNVEEGGSLTIIATALVDTGSKMDEVIYEEFKGTGNMELHLSRKIAEKRVFPAIDFNRSGTRREELLAKADELQKMWILRKIVHPMGEIDSMEFLIGKLSMTKTNDEFFDAMRRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z0X7</accession>
    <name>D0Z0X7_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative peptide ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_003191</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302117.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003191"/>
    <dbReference type="EnsemblBacteria" id="EEZ42158">
        <property type="protein sequence ID" value="EEZ42158"/>
        <property type="gene ID" value="VDA_003191"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4172">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1303270at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="4"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="308"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="40"/>
            <end position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="346"/>
            <end position="353"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ42158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="575" mass="63959" checksum="3C7CE246F252C63B" modified="2010-01-19" version="1">MALLEVNNLRIEYPSRHGVFAAVKSLSFSIERGEIVGVVGESGAGKSTVGNGVIDLLSPPGHIASGEVLLDGEVISGLTPDQMRKIRGNKVGFIFQDPMTSLNPLFTIEQQLTETIVTNLRLSSSQAYQRALELLQQVGINDPEIRIKQYPHQFSGGMRQRVVIAIALAGEPDLIIADEPTTALDVSIQDQILNLIRKLCLEKNVGCMLVTHDMGVVANVTDKVAVMYQGDLVEFGTTDQVLHHPNHAYTRSLISAVPRSDIKLKRFPLVSYIEQAKEMKPLDIKTHWLGQREQQRDYQGALLQVNQVNLRFITKDSFFASRREYVQASNNVSFDIYEGETFGLVGESGSGKSTIARVIAGLYPPNSGQVVFEGIDLTALTSERQRQPFRRQMQMVFQNPYTSMNPRMRIFDIIAEPIRFHRLTENETQTRAVVNDLLDHVGLGRAAGVKYPHEFSGGQRQRISIARALATRPRLLICDEPTSALDVSVQAQILNLLKDLQDELGLTMLFISHDLPVIRQMCDRVGVMQYGQLLEVAATEKLFTDPEHSYSKKLISLMPEFTGLKESPQPVAALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z120</accession>
    <name>D0Z120_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="16">ATP synthase B chain</fullName>
            <ecNumber evidence="16">3.6.3.14</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">VDA_003234</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.</text>
    </comment>
    <comment type="function">
        <text evidence="12">F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the ATPase B chain family.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.14" evidence="16"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003234"/>
    <dbReference type="EnsemblBacteria" id="EEZ42201">
        <property type="protein sequence ID" value="EEZ42201"/>
        <property type="gene ID" value="VDA_003234"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0711">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045263">
        <property type="term" value="C:proton-transporting ATP synthase complex, coupling factor F(o)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015078">
        <property type="term" value="F:proton transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015986">
        <property type="term" value="P:proton motive force-driven ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028987">
        <property type="entry name" value="ATP_synth_B-like_membr_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002146">
        <property type="entry name" value="ATP_synth_b/b'su_bac/chlpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005864">
        <property type="entry name" value="ATP_synth_F0_bsu_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00430">
        <property type="entry name" value="ATP-synt_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81573">
        <property type="entry name" value="SSF81573"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01144">
        <property type="entry name" value="ATP_synt_b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="4" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 14" id="KW-0138">CF(0)</keyword>
    <keyword evidence="15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 14" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 14" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 14" id="KW-0813">Transport</keyword>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="30"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00025614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EEZ42201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="135" mass="14990" checksum="FF681144850751B7" modified="2010-01-19" version="1">MKYVWPPIMQAIEERQKKIADGLAAADRATKDLDLAKANASDQLKEAKRAASEIIEQANKRKSQILDEAKAEALTEREKIIAQGMAEIEAERNRARDELRKQVATLAVIGAEKIIEHSIDKDAQAEILSKVTAEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z139</accession>
    <name>D0Z139_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glycine--tRNA ligase alpha subunit</fullName>
            <ecNumber evidence="9">6.1.1.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Glycyl-tRNA synthetase alpha subunit</fullName>
            <shortName evidence="9">GlyRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">glyQ</name>
        <name evidence="10" type="ORF">VDA_003253</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly)</text>
            <dbReference type="Rhea" id="RHEA:16013"/>
            <dbReference type="Rhea" id="RHEA-COMP:9664"/>
            <dbReference type="Rhea" id="RHEA-COMP:9683"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78522"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.14"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3 9">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.14" evidence="9"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003253"/>
    <dbReference type="EnsemblBacteria" id="EEZ42220">
        <property type="protein sequence ID" value="EEZ42220"/>
        <property type="gene ID" value="VDA_003253"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0752">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004820">
        <property type="term" value="F:glycine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006426">
        <property type="term" value="P:glycyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00733">
        <property type="entry name" value="GlyRS_alpha_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00254">
        <property type="entry name" value="Gly_tRNA_synth_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006194">
        <property type="entry name" value="Gly-tRNA-synth_heterodimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002310">
        <property type="entry name" value="Gly-tRNA_ligase_asu"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02091">
        <property type="entry name" value="tRNA-synt_2e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01044">
        <property type="entry name" value="TRNASYNTHGA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00388">
        <property type="entry name" value="glyQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50861">
        <property type="entry name" value="AA_TRNA_LIGASE_II_GLYAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ42220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="271" mass="31073" checksum="B849FCC3546C6446" modified="2010-01-19" version="1">MEVGAGTSHPMTCLRALGPEPIATAYVQPSRRPTDGRYGENPNRLQHYYQFQVMLKPSPDNIQELYLGSLEALGIDTQIHDIRFVEDNWENPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGLECKPVTGEITYGIERLAMYIQGVDSVYDLVWTDGPLGKVTYGDIFHQNEVEQSTYNFEHADVDFLFTFFDQNEKECQQLLELETPLPLPAYERILKAAHAFNLLDARKAISVTERQRYILRIRNLTKQVAEAYYASREALGFPMCKKDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1G9</accession>
    <name>D0Z1G9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Regulator of ribonuclease activity A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rraA</name>
        <name evidence="3" type="ORF">VDA_003383</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homotrimer. Binds to both RNA-binding sites in the C-terminal region of Rne and to RhlB.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RraA family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302613.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003383"/>
    <dbReference type="EnsemblBacteria" id="EEZ42350">
        <property type="protein sequence ID" value="EEZ42350"/>
        <property type="gene ID" value="VDA_003383"/>
    </dbReference>
    <dbReference type="GeneID" id="57340167"/>
    <dbReference type="eggNOG" id="COG0684">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1614890at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060698">
        <property type="term" value="F:endoribonuclease inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019899">
        <property type="term" value="F:enzyme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16841">
        <property type="entry name" value="RraA_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00471">
        <property type="entry name" value="RraA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010203">
        <property type="entry name" value="RraA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005493">
        <property type="entry name" value="RraA/RraA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036704">
        <property type="entry name" value="RraA/RraA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014339">
        <property type="entry name" value="RraA_gpbac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03737">
        <property type="entry name" value="RraA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89562">
        <property type="entry name" value="SSF89562"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01935">
        <property type="entry name" value="NOT-MenG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02998">
        <property type="entry name" value="RraA_entero"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ42350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="161" mass="17335" checksum="4E53F1C9E0A0820A" modified="2010-01-19" version="1">MEYNTSELCDIYLDQVDVVEPMFNSYGGRGSFGGQITTVKCFEDNGVLRSVLEQSGVGRVLLVDGGGSLRRALIDIDIAQLAAENEWEGIVVYGCVRHVDELDELDLGIQALASMPVGADNQSVGEVDVPVNFGGVTFLPEDHLYADNTGVILSPEPLDLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1I3</accession>
    <name>D0Z1I3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Acetylglutamate kinase</fullName>
            <ecNumber evidence="8">2.7.2.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">N-acetyl-L-glutamate 5-phosphotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">NAG kinase</fullName>
            <shortName evidence="8">NAGK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">argB</name>
        <name evidence="10" type="ORF">VDA_003397</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamyl 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:14629"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:44337"/>
            <dbReference type="ChEBI" id="CHEBI:57936"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 2/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the acetylglutamate kinase family. ArgB subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.8" evidence="8"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005302640.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003397"/>
    <dbReference type="EnsemblBacteria" id="EEZ42364">
        <property type="protein sequence ID" value="EEZ42364"/>
        <property type="gene ID" value="VDA_003397"/>
    </dbReference>
    <dbReference type="GeneID" id="57340153"/>
    <dbReference type="eggNOG" id="COG0548">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="901370at2"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00107"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003991">
        <property type="term" value="F:acetylglutamate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042450">
        <property type="term" value="P:arginine biosynthetic process via ornithine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00082">
        <property type="entry name" value="ArgB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004662">
        <property type="entry name" value="AcgluKinase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037528">
        <property type="entry name" value="ArgB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000728">
        <property type="entry name" value="NAGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00761">
        <property type="entry name" value="argB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2 8" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AA_kinase" evidence="9">
        <location>
            <begin position="7"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="46"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="8">
        <location>
            <position position="10"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="8">
        <location>
            <position position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ42364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="260" mass="26855" checksum="B462FCC1FC1DC610" modified="2010-01-19" version="1">MADLCPLVIKLGGAVLSCQETLSKLFLAISQYQAAAHRPIVLVHGGGYLVDELLKKLALPTVKKQGLRVTPNDQIELITGALAGTANKLLQAQAIKAQVPSVGLSLADGGLCQVSQLDPELGAVGQAQAGDGLLVLSLLQNGYLPIVSSIGLTAEGELMNVNADQAAVAVAKAIDGELVLLSDVSGVLDGKGRLIASLTQNDAEALIAQAVITDGMVVKVRAAFLAAQELGRSIEVASWRYPDKLALLFAGQSIGTKFSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1T9</accession>
    <name>D0Z1T9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">MSHA biogenesis protein MshQ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_003503</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003503"/>
    <dbReference type="EnsemblBacteria" id="EEZ42470">
        <property type="protein sequence ID" value="EEZ42470"/>
        <property type="gene ID" value="VDA_003503"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502ZIXT">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ42470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="1394" mass="154453" checksum="D194EE6E76D2AE9F" modified="2010-01-19" version="1">MWQQKYNNDTYTRSMGARGKIMRIYLLIFAILSCLFLRTAMASTSQQFEFGTISGPCVDYSCDINFKNNYNDPLIFLMPSFADGHWNDAPSTLRVISANGGVGGKARIRQYFAPYNHNDLILLDPGHCNRANWCLTKQPMTNISYFVIENGADINLGSKGRIIAKSISTNKYLRYKQTASKNNSEEINTKDLIGKNQLENFGVIVESQAVNNISEQLPPNGIFENQYVIDKILDYPFYIKENYTNRWYTPAVIKNSNSFYLALDRGETVINGDYYNNYNYYQKVGYLLVTGAGQYKGLLFSLGHGSTPNTLGQNKDYKGFKNVTLPSERQCGEVTEVPHSSQFKGLPFILASKNSRNGSDGGIFRLCRLKQESRNSDDIEVSFVTDEDLNEPRRGKTNESCGGQDCIERRHANESFGFMAFQQAVDSETCELFPGPAQSWDKYDSELEGNHNVSIIGSPVINGSYHLGFTEIDNESGGNNQFCNGKECFPAQGYTHLYAKKAILDTWPGIDDGYFSLSSISSSKKEYWFQTLSLEGNKVAKFPNGTIIHTRDLSVGSNSWLSSQSENPDDLIIYVHGESGPWKRDFIDMTKGAQVHALIYSERDLKMSYGNGNNETTRLVGSITAPDIEMVGKKDGNYNLKSEIIGQSSCFESEPNYSLTITPKIKTNTLCDDQPITFNVQASDGSSSNYTGKIHVTISSRFGGQWAGNANFTNAIKFSENTSFDLDVANNQAKFWLRANDAEKITVSGSIDRMEGAAPIGEYSFIPGGFKITPQSANIIAGKPFSATITAVACPAKGKEKPISMYDGEKTLDFSTQYQSPKTGNVAVNILRDNSQFTTSATIRFNKGESEPLTLQYSDAGSLIWNVTDPNCTTESCLLTDGKNRQAQELKRLLPDGLKGSMTINSRPWTFAICPAQGKNIDGTALGGQPLAAAGDYFYLHVRPVVWQQGGSESDPISTTAYNLCSAAITPNFFKSDAPRLNVNISLNEKQPVSPVGGDYGQLSGNLQANNHTGNDYLNYRLTWSEVGSVPLKASGQSDYLGMTINSGYRSAGRIYPAFFGSTHNELTPAMGSFTYMGQPFPVHWVVNAFNRQGKAVGNYDKFAPKLTAKFAFDIKNSGSNSEERLLLQQPLPQTWSHNGENHHSYMSYQSDVTFARQGFQALDKVTTPGGPYNSWQLWLTITNPNAGRPAQDPRRLTPELCNPNDGCSDPDLSKMTELRLGNTNPMRYGRMVLQDAAGDIRGPVAIPLRVEYWNGAAFETNADDSSSHFDGRNYCSQILYPQPDKKNIPSTSGTGNVDQGVASNEKLVAYPDVPVLEPFKQQVRFWQRLSNSTEPKGNGISCRGTYTYQPWLSYNWRKKGDEDPSAIVTFGVYQGNKRIIYRAEAGVASSNYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1V1</accession>
    <name>D0Z1V1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nucleotide-binding protein VDA_003515</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003515</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Displays ATPase and GTPase activities.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RapZ-like family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303663.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003515"/>
    <dbReference type="EnsemblBacteria" id="EEZ42482">
        <property type="protein sequence ID" value="EEZ42482"/>
        <property type="gene ID" value="VDA_003515"/>
    </dbReference>
    <dbReference type="GeneID" id="57340012"/>
    <dbReference type="eggNOG" id="COG1660">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1603998at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00636">
        <property type="entry name" value="RapZ_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005337">
        <property type="entry name" value="RapZ-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30448">
        <property type="entry name" value="PTHR30448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03668">
        <property type="entry name" value="ATP_bind_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005052">
        <property type="entry name" value="P-loopkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="8"/>
            <end position="15"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="56"/>
            <end position="59"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="283" mass="32291" checksum="1058D7ACFA47E317" modified="2010-01-19" version="1">MRLMVVSGRSGSGKSVALRVLEDLGYYCVDNLPVNLLTQFIETIGDEQQDVAVSLDVRNMPSDTQALEMILNDLSNKVDLNILFLDADNKELVKRYSETRRLHPLSRDNMSLEQAILSESKIMEVIKERADLVVDTTGKSIHDLSETVRSRVLGRESRELILVFESFGFKYGLPTDADYVFDVRFLPNPHWVPELKPQTGLDEGVKTFLASHAEVNQLIYQVRNFIETWLPMLEKNNRSYVTVAIGCTGGQHRSVYIAQQLAEYFQRSGQQIRIRHRTLEGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1V3</accession>
    <name>D0Z1V3_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Lipopolysaccharide export system ATP-binding protein LptB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">VDA_003517</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell inner membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
            <orientation evidence="3">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303670.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003517"/>
    <dbReference type="EnsemblBacteria" id="EEZ42484">
        <property type="protein sequence ID" value="EEZ42484"/>
        <property type="gene ID" value="VDA_003517"/>
    </dbReference>
    <dbReference type="GeneID" id="57340008"/>
    <dbReference type="eggNOG" id="COG1137">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1220708at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03218">
        <property type="entry name" value="ABC_YhbG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032823">
        <property type="entry name" value="BCA_ABC_TP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030921">
        <property type="entry name" value="LPS_export_LptB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12399">
        <property type="entry name" value="BCA_ABC_TP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04406">
        <property type="entry name" value="LPS_export_lptB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="13">
        <location>
            <begin position="4"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00026081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EEZ42484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="241" mass="26917" checksum="3865F7392CF7473C" modified="2010-01-19" version="1">MAILKAEHLAKSYNGRKVVSDVSLQVESGKIVGLLGPNGAGKTTSFYMIVGLVARDEGAITIDDTDISLQPMHNRSRMGIGYLPQEASIFRRLSVHDNLMAVLQTRKELTKQERQDKLEELLDEFNIQHIRNSMGMALSGGERRRVEIARALAANPKFILLDEPFAGVDPISVIDIKKIIEHLRDRGLGVLITDHNVRETLDVCEHAYIVSQGQLIANGTPEQVLNDEHVKRVYLGDQFRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1X4</accession>
    <name>D0Z1X4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Stringent starvation protein B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_003538</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003538"/>
    <dbReference type="EnsemblBacteria" id="EEZ42505">
        <property type="protein sequence ID" value="EEZ42505"/>
        <property type="gene ID" value="VDA_003538"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2969">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007481">
        <property type="entry name" value="SspB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036760">
        <property type="entry name" value="SspB-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37486">
        <property type="entry name" value="PTHR37486"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04386">
        <property type="entry name" value="SspB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101738">
        <property type="entry name" value="SSF101738"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ42505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="125" mass="13464" checksum="088F62DBBEF165D0" modified="2010-01-19" version="1">MDFVSDGQIVLNVVPRAVGNLELGNEAVSFNARFGGRPHSVIVPLYAVLAIYARENGAGTMFEPEPAYDAQLENGEGIFDTEDMVAPKATLSAVEEGELESVGDDDHPDDEPPKPRGRPTLRVVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1X7</accession>
    <name>D0Z1X7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Penicillin-binding protein activator LpoA</fullName>
            <shortName evidence="7">PBP activator LpoA</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">lpoA</name>
        <name evidence="10" type="ORF">VDA_003541</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a).</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Interacts with PBP1a.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the LpoA family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ42508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_003541"/>
    <dbReference type="EnsemblBacteria" id="EEZ42508">
        <property type="protein sequence ID" value="EEZ42508"/>
        <property type="gene ID" value="VDA_003541"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3107">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031241">
        <property type="term" value="C:periplasmic side of cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030234">
        <property type="term" value="F:enzyme regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01890">
        <property type="entry name" value="LpoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007443">
        <property type="entry name" value="LpoA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38038">
        <property type="entry name" value="PTHR38038"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04348">
        <property type="entry name" value="LppC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2 7" id="KW-0133">Cell shape</keyword>
    <keyword evidence="6 10" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0564">Palmitate</keyword>
    <keyword evidence="3 7" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008952224" description="Penicillin-binding protein activator LpoA" evidence="9">
        <location>
            <begin position="25"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="601"/>
            <end position="640"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ42508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="640" mass="70562" checksum="E0B1A9195FAA814E" modified="2010-01-19" version="1">MNSMIKFTHKRKSVTRLMAPVAFAVLMAGCSSNPYFHQAPNTDITAAATLSSADYLSKAQASEGADRINWDLLALKALIKEGRYPQAEQLTDQLSRQTMSPMQIAEWQLARADLRNVQGNAQLALSGLQFQPSWSLATSQYRRYYQLRAKLLEQLDQSFAAARERTKLDLYLSPEQKQANWQALWQDLSPYSNEQLSQARIGKDETVLQGWAQLAMLKNSYGYNPEQLKEKVNQWLSMNPYHPANAYLPEQLDNIMNMKAPQLNKVALLLPLSGRFSAQGQAVRDGFMNAILDDPNRNPNAVLNVYDTDAESIASIVGKLQQNGTEFVVGPLRKDKIVEFQKANSANVPMLALNEPSVITSSQPTACYYSLSPEQEAEQAAEHIYQEGKHYPIVLFPDSSYGQRVSAAFVNQWKELTGYAPFSGSFGSKAQIQQQISQIFGPTARRSRANQIAQISASTGIEGSRAADAIYIIGSKSELTLIKPFIELNIDPSIAPPAMYASSRSNSDSKSFELNGVEYSDIPLLVSPDPSFMAHFNQLWPNQGKTSVRLHAFGMDAYKVATELPQLRAIPGFTASGATGKLSVDSQCVVQRQLDWGTFGSTPITEEAVTDQTDTTATDDASDTPDSTTSVSEQDSSNTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z1Z8</accession>
    <name>D0Z1Z8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF1456 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001984</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40952">
        <property type="protein sequence ID" value="EEZ40952"/>
        <property type="gene ID" value="VDA_001984"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4807">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009921">
        <property type="entry name" value="DUF1456"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07308">
        <property type="entry name" value="DUF1456"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1456" evidence="2">
        <location>
            <begin position="25"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="99" mass="11782" checksum="961D84084D6DE610" modified="2010-01-19" version="1">MNGLINLKRGKREGEQPEPESRLTNNMVFQKLRIALNLKAEEILEVLELANFRLSKHELSAFFRKPENKHYRECKDQILRNFLLGVQLQLRPEDTEYQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z221</accession>
    <name>D0Z221_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3-deoxy-manno-octulosonate cytidylyltransferase</fullName>
            <ecNumber evidence="2">2.7.7.38</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">CMP-2-keto-3-deoxyoctulosonic acid synthase</fullName>
            <shortName evidence="2">CKS</shortName>
            <shortName evidence="2">CMP-KDO synthase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">kdsB</name>
        <name evidence="3" type="ORF">VDA_001870</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>3-deoxy-alpha-D-manno-oct-2-ulosonate + CTP = CMP-3-deoxy-beta-D-manno-octulosonate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23448"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:85986"/>
            <dbReference type="ChEBI" id="CHEBI:85987"/>
            <dbReference type="EC" id="2.7.7.38"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Nucleotide-sugar biosynthesis; CMP-3-deoxy-D-manno-octulosonate biosynthesis; CMP-3-deoxy-D-manno-octulosonate from 3-deoxy-D-manno-octulosonate and CTP: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the KdsB family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.38" evidence="2"/>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298848.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001870"/>
    <dbReference type="EnsemblBacteria" id="EEZ40838">
        <property type="protein sequence ID" value="EEZ40838"/>
        <property type="gene ID" value="VDA_001870"/>
    </dbReference>
    <dbReference type="GeneID" id="57342006"/>
    <dbReference type="eggNOG" id="COG1212">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1345588at2"/>
    <dbReference type="UniPathway" id="UPA00358">
        <property type="reaction ID" value="UER00476"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008690">
        <property type="term" value="F:3-deoxy-manno-octulosonate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033468">
        <property type="term" value="P:CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009103">
        <property type="term" value="P:lipopolysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02517">
        <property type="entry name" value="CMP-KDO-Synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00057">
        <property type="entry name" value="KdsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003329">
        <property type="entry name" value="Cytidylyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004528">
        <property type="entry name" value="KdsB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02348">
        <property type="entry name" value="CTP_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00466">
        <property type="entry name" value="kdsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0448">Lipopolysaccharide biosynthesis</keyword>
    <keyword evidence="2 3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="248" mass="27744" checksum="D6199BDBAEE866CE" modified="2010-01-19" version="1">MSFTVIIPARYQSTRLPGKPLADIGGKPMVQWVYEQACKSGADKVIVATDDQRVFDAVQAFGGEVCMTRSDHQSGTERLAEVVEKYNLADDHIVVNVQGDEPLIPDTIIRQVADNLAHKNAPMATLAVEIDHEDEVFNPNAVKVVTDKDGYAMYFSRASIPWDRDHFAQQPAQIHHNLLRHIGIYAYRAGFINTYINWQPTALEQIEALEQLRVLWYGEKIHVDVAIDAPPAGVDTPEDLEKVRALIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z278</accession>
    <name>D0Z278_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001923</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000001">
        <property type="protein sequence ID" value="EEZ40891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005298949.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ40891">
        <property type="protein sequence ID" value="EEZ40891"/>
        <property type="gene ID" value="VDA_001923"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG50331WV">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1275952at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="200"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="247"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="279" mass="31240" checksum="731B3872B2BB1E71" modified="2010-01-19" version="1">MKQFFTLLSKELIEHKVIFRIPLFLALFLVLNFILILYNSNDVSFNFKINGWEQFDNIQLSMGFGGVIGSINTLICGLVAVICFFAYMPKTLLKEKQEGSWNFWRSMPVSNVKTLGAKLVVGLIVIPAISVILLVFADFCFMIVAKLLLSDALLQSSSINLHEMFMHIMSYINRMIVVSIGLLPIACVLLVLSQLTNHPLIILFAVTVMVKVLGYTINVLSGFSQFVSDWNNISVSALFDTNPWQELAIFSSIELGSVLMITVGLFCYAVKLMSTELNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z287</accession>
    <name>D0Z287_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DAO domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000538</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304662.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000538"/>
    <dbReference type="EnsemblBacteria" id="EEZ39518">
        <property type="protein sequence ID" value="EEZ39518"/>
        <property type="gene ID" value="VDA_000538"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0654">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="618459at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAO" evidence="1">
        <location>
            <begin position="14"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="492" mass="54264" checksum="168D47376F7CD5F5" modified="2010-01-19" version="1">MVFHNNNKQSNCKVGIIGGGVAGSTAALRLAELGIDVELFEEGKSLVNGPPICHLHAGGNLYREISDEQCAVLLKQSIDTVRAYPASVNVRPTVLAVPTHDAGDPKELLPRLTMLQHLYAQLVQQDPCNSVLGNPDDYYRLYNEADITALAALEQPLSPQTPDEWMIPVAKSINPKQFKYPIVMVQEYGLSVFRIAATVSLALAQKSNCIVHTSTKVTNLCYLADSQSWTLEYSNNSINKPQTKHFDYIVNASGFRTGTIDDLIHVKRDRLVEFKSAYVTHWQDCHAQWPEVIFHGERGTPQGMAQLTPYPNGYFQLHGMTEDITLFKDGLVHSTTTSSQPHLAASFLTKISDRWQQQEVSERTERAIAHMSQFVPSFTTATVGGMPLFGAQQIPGLDPTLRAADVSFAAQRYARSEIVKASSALSAANEIVADLIANKLIDPLNNTDIIEEEFKTNQTLSLDDVVNKAVAIAKERGYPQELAIPTGYQRAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2C1</accession>
    <name>D0Z2C1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">LysM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VDA_000572</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">CIP 102761</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the YkuD family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304740.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000572"/>
    <dbReference type="MEROPS" id="C82.A03"/>
    <dbReference type="EnsemblBacteria" id="EEZ39552">
        <property type="protein sequence ID" value="EEZ39552"/>
        <property type="gene ID" value="VDA_000572"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1376">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="975147at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071972">
        <property type="term" value="F:peptidoglycan L,D-transpeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16913">
        <property type="entry name" value="YkuD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005490">
        <property type="entry name" value="LD_TPept_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041597">
        <property type="entry name" value="Ldt_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038063">
        <property type="entry name" value="Transpep_catalytic_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17969">
        <property type="entry name" value="Ldt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03734">
        <property type="entry name" value="YkuD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141523">
        <property type="entry name" value="SSF141523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="SSF54106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0574">Periplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003019922" description="LysM domain-containing protein" evidence="7">
        <location>
            <begin position="20"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="8">
        <location>
            <begin position="36"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EEZ39552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="300" mass="33011" checksum="4473F30320A9B87B" modified="2010-01-19" version="1">MYRALLFSLTCLFSSAVNAIEFKLPDDGSNIVGTIEYYEVEKGESLSDIANKFNVGFLALLAANKDVDPFLPQPGTLLEIPTQVILPNVPHNGVTINLAELRLYYFPKDDPSKVYVFPIGIGRVGRETPSMTTSISQKIRHPTWTPTANIRKEYAAKGVTLPPVVAAGPNNPLGDYAMRLAYGHGEYLIHSTNKDFGIGMRVSSGCIRMNPWDIEWLFPQIPKGTPVRIINDPLKHTVDKDGSIIVEVHQPLSKDEEQLGEFKPVTADDSLIASLGDDNAAKQRLAQELKQQTGIPTVVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2I6</accession>
    <name>D0Z2I6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000637</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304932.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39617">
        <property type="protein sequence ID" value="EEZ39617"/>
        <property type="gene ID" value="VDA_000637"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5032V18">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1124413at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036280">
        <property type="entry name" value="Multihaem_cyt_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48695">
        <property type="entry name" value="SSF48695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="406" mass="45719" checksum="EE048ABA94F87A3D" modified="2010-01-19" version="1">MKKTLLFTFLATMIACGGDSNPDNTPQNPPSDDSPQDLAIKISDLSNGYYGKMYTDNGDEVSIKANDILPMQSQFIDELKQYIPQDSVDKYQQYLEDFANYDLKTETEKVLFQNALLNAMLDEIDQKTRQRYQPSVRLFQHHTHLLFPISRIDDFPVLTDFLFTRSILEHLPLYIPDTEDDYIQTCRENNVPIPPDWGSGDWNYMGDAEVDFLKNELTEIWAYSDPNVAGTCIALPRKESGVVSLLGIICQSSTTGKACFWDNLSKENGLRITGGDDLTFAIEDIHNGDILAENCTECHRGSNVFLIHPGTNLDISDQYTLELAVRYTPVSQQEQWQNPPAHTEFGTGTCASCHEIADLSYGYCTLVLTNAANMTMPNLENPAGWNNSHDIYGQHLAQIIEDCRAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2I9</accession>
    <name>D0Z2I9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD superfamily hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000640</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304941.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000640"/>
    <dbReference type="EnsemblBacteria" id="EEZ39620">
        <property type="protein sequence ID" value="EEZ39620"/>
        <property type="gene ID" value="VDA_000640"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1011">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1669868at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="199" mass="22839" checksum="143C37796C14AC97" modified="2010-01-19" version="1">MLKNVIFDFGAVLFEWNPNQIVKTFTPSDEEQNLLLQQVLQHPDWISLDRGTMLIAEVIPKFSARTGLPENQIEDFIHHVIQSLTLINATLDIVELSLSSFKTFYLTNMSESFFESLNEQHPIISQFDGGIVSGKELMIKPEPEIFQLLLDRYALKAEESLFIDDNLDNILAAKQLGFDTVLFDKSSQCYKQLLEKIRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2K7</accession>
    <name>D0Z2K7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 8">UDP-glucose 4-epimerase</fullName>
            <ecNumber evidence="5 8">5.1.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">VDA_000658</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>UDP-alpha-D-glucose = UDP-alpha-D-galactose</text>
            <dbReference type="Rhea" id="RHEA:22168"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="ChEBI" id="CHEBI:66914"/>
            <dbReference type="EC" id="5.1.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 8">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 8">Carbohydrate metabolism; galactose metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 8">Belongs to the NAD(P)-dependent epimerase/dehydratase family.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.2" evidence="5 8"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304975.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000658"/>
    <dbReference type="EnsemblBacteria" id="EEZ39638">
        <property type="protein sequence ID" value="EEZ39638"/>
        <property type="gene ID" value="VDA_000658"/>
    </dbReference>
    <dbReference type="GeneID" id="57342992"/>
    <dbReference type="eggNOG" id="COG1087">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1597849at2"/>
    <dbReference type="UniPathway" id="UPA00214"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003978">
        <property type="term" value="F:UDP-glucose 4-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006012">
        <property type="term" value="P:galactose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd05247">
        <property type="entry name" value="UDP_G4E_1_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005886">
        <property type="entry name" value="UDP_G4E"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01179">
        <property type="entry name" value="galE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7 8" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="9">
        <location>
            <begin position="4"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EEZ39638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="338" mass="36958" checksum="FDEF608A00DC5176" modified="2010-01-19" version="1">MRVLVTGGMGYIGSHTCVQMIEAGMTPIILDNLYNSKETVLERVENLTGVRPAFYKGDIRDRAFLDSVFAENEIDAVIHFAGLKAVGESVEKPLEYYDNNVHGTLVLVEAMRAAGVNSLIFSSSATVYGDPASVPITEDFPTSATNPYGRSKLMVEECLTDIQHAYPEMSITLLRYFNPVGSHKSGTMGEDPQGIPNNLMPFISQVAVGRREFLSVFGDDYPTVDGTGVRDYIHVVDLADGHIAALKYKGSEAGLHIYNLGTGNGNSVLQMVSAFEKASGAKVAYKIAPRRPGDIAECWADPAKAKRELHWEATHTIEDMTADTWRWQSTNPNGYPDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2K9</accession>
    <name>D0Z2K9_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GGDEF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000660</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304981.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000660"/>
    <dbReference type="EnsemblBacteria" id="EEZ39640">
        <property type="protein sequence ID" value="EEZ39640"/>
        <property type="gene ID" value="VDA_000660"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2199">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="157"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="2">
        <location>
            <begin position="219"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="350" mass="39477" checksum="7C5507FC3EB290C6" modified="2010-01-19" version="1">MATLVKSTQLESVNFAYIELSKNTLQRQLSLLFTSSGIICTLVAFAYFVAKTSLVSLYSALLGLSISYTLAIFNRININPKVLMWIFILSTTLACITGYSFSETHHISNTIGLTIPLLCFFALKQKTAAWYSGLFGFCYVILSISEIGEKQLQLNDALQNMSAYSLVFVMAYLLAKHRNEAIHCVKQTATNDFLTGLYNREGLLPIYQAEAARSERYLKDFSMLLLSVDDFKNINDRYGLETGDKVLMMLTKCLQQLSRKEDTIARLGGTEFCLLLPDTSLEQAEKFALRLQEQVNSWVLELESGHRISVTLSMGLTPIQFREFNYDYIKADNAVMRAKHWGGNQLAISE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2P6</accession>
    <name>D0Z2P6_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Manganese transport system ATP-binding protein mntA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_000697</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305084.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000697"/>
    <dbReference type="EnsemblBacteria" id="EEZ39677">
        <property type="protein sequence ID" value="EEZ39677"/>
        <property type="gene ID" value="VDA_000697"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1121">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1721927at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="14"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="46"/>
            <end position="53"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="263" mass="29158" checksum="29835773DCD68EBD" modified="2010-01-19" version="1">MKKVTTSSVLGPSIELKNLNLHYGENTILTDINHRFSAGECHVVMGPNGGGKTSLLRSILGLTPFSGQIDIQWASQELANKSGVIGYVPQKAMFEASLPLTVMDFILLNQTRFPLFWRKRGKEQQNALAQLERVGMASRADRRMGQLSGGEQQRVLFAQALLDDPALLVLDEPTTGMDEQGVRYLESLIKECVKEGKTVLAVHHDVTAVRRLDAHVHVVNRILVDSGRHQDILVPEKIERIFNHYTSSPMNSSFNSSTSNKVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2R1</accession>
    <name>D0Z2R1_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Dipeptide and tripeptide permease B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">dtpB</name>
        <name evidence="6" type="ORF">VDA_000712</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Proton-dependent permease that transports di- and tripeptides.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell inner membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family. DtpB subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39692">
        <property type="protein sequence ID" value="EEZ39692"/>
        <property type="gene ID" value="VDA_000712"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3104">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071916">
        <property type="term" value="F:dipeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015333">
        <property type="term" value="F:peptide:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042937">
        <property type="term" value="F:tripeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17346">
        <property type="entry name" value="MFS_DtpA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01879">
        <property type="entry name" value="PTR2_DtpB_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023778">
        <property type="entry name" value="AA/pep_transptr_DtpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005279">
        <property type="entry name" value="Dipep/tripep_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000109">
        <property type="entry name" value="POT_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018456">
        <property type="entry name" value="PTR2_symporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11654">
        <property type="entry name" value="PTHR11654"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11654:SF102">
        <property type="entry name" value="PTHR11654:SF102"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00854">
        <property type="entry name" value="PTR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00924">
        <property type="entry name" value="yjdL_sub1_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01023">
        <property type="entry name" value="PTR2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3 5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 5" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="91"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="114"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="151"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="178"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="220"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="244"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="274"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="325"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="355"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="383"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="423"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="463"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ39692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="495" mass="54284" checksum="C0EFD93A1E48F0FF" modified="2010-01-19" version="1">MWKRLNTAMKTNVSIFDQPKPFKMIFFIELWERFGYYGVQGILAVYFVKQLGFTQQESFVTFGAFAALVYGLVSVGGYVGDHILGTKRTMVLGAIVLASGYFLMGFSILHKHFIFYALGAIAVGNGLFKANPSSLLSKCYEHGDSRLDGAFTLYYMAINIGSLVSLSLTPVIAEHFGYTTAFVICGLGLIASLISYALFCSTVAGIGSFPDSQPLKIKSLFVVILGTVCATFFCAWLLRNVFWANTVLAIIGVAVVTFFLYECFKAKGAARQKMLVAFVLMLQAIVFYVLYAQMPTSLNFFAIYNVRTDLFGIHLNPVSLQALNPFWVVICSPILAYLYTSLGNKGRDFSMPVKFTLGMFLCALGFLAVAAAGMWFADPNGKVAIWWVVATYFFQSIGELLISGLGLAMVASLVPQRLMGFTMGAWFLTQAASFIIGGYVASLTAVKGNVTNPLETLPLYTEVFQNIGLFTLVVAIIMAVTAPMLNRMMMAKDIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2U4</accession>
    <name>D0Z2U4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000745</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305232.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39725">
        <property type="protein sequence ID" value="EEZ39725"/>
        <property type="gene ID" value="VDA_000745"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2055010at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="2"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="149" mass="17482" checksum="3B37163A5D5F947F" modified="2010-01-19" version="1">MFSVKKATSDDLSKISPLYEEYLTFYHVDFSDKNPQKYLEERLSNNESVIYYVEDDSGNYVGFTQLYPLFCSLEMNRTWLLYDLFVAESARCHGIAQLLLDQADKLANETDASFIMLSTAIDNLKAQKLYEKNDYEKDVEFFTYLKHLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2V0</accession>
    <name>D0Z2V0_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Peptidoglycan glycosyltransferase MrdB</fullName>
            <shortName evidence="6">PGT</shortName>
            <ecNumber evidence="6">2.4.1.129</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Cell elongation protein RodA</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Cell wall polymerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Peptidoglycan polymerase</fullName>
            <shortName evidence="6">PG polymerase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">mrdB</name>
        <name evidence="6" type="synonym">rodA</name>
        <name evidence="7" type="ORF">VDA_000751</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Peptidoglycan polymerase that is essential for cell wall elongation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>[GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-di-trans,octa-cis-undecaprenyl diphosphate + beta-D-GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate = [GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-di-trans-octa-cis-undecaprenyl diphosphate + di-trans,octa-cis-undecaprenyl diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23708"/>
            <dbReference type="Rhea" id="RHEA-COMP:9602"/>
            <dbReference type="Rhea" id="RHEA-COMP:9603"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58405"/>
            <dbReference type="ChEBI" id="CHEBI:60033"/>
            <dbReference type="ChEBI" id="CHEBI:78435"/>
            <dbReference type="EC" id="2.4.1.129"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell inner membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the SEDS family. MrdB/RodA subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.129" evidence="6"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305248.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000751"/>
    <dbReference type="EnsemblBacteria" id="EEZ39731">
        <property type="protein sequence ID" value="EEZ39731"/>
        <property type="gene ID" value="VDA_000751"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0772">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1133883at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008955">
        <property type="term" value="F:peptidoglycan glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02079">
        <property type="entry name" value="PGT_RodA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001182">
        <property type="entry name" value="FtsW/RodA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011923">
        <property type="entry name" value="RodA/MrdB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30474">
        <property type="entry name" value="PTHR30474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30474:SF1">
        <property type="entry name" value="PTHR30474:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01098">
        <property type="entry name" value="FTSW_RODA_SPOVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02210">
        <property type="entry name" value="rodA_shape"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 6" id="KW-0133">Cell shape</keyword>
    <keyword evidence="6" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="69"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="108"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="133"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="155"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="176"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="265"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="298"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="331"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="365" mass="40184" checksum="F8AD8C6B35C014C0" modified="2010-01-19" version="1">MFKRFQPHIDYPLLFAILTLITLSTLSVWSASSFSEPIIERHLVRAALAIGALIFMSCISPLRYQRSAPYLYGLTVLLLVGVFVLGDSTNGSQRWLEIGPIRFQPSELVKVAIPLMMAWIIIADAGRPTIKKIFLCLLVTSVPAGLIFIQPDLDGAIFTIIYALFVLYFAGMAWKIILSVLGVVAVSLPVSWYFVMAPYQKKRITQFLNPESDPLGAGYQIIQSKIAIGSGGIKGKGWMDATQGNLGFIPESHTDFIFSTFAEEWGYIGSVVLLALYLFITARVLWLACQTESPFSRLVSAAFALSFFLYSFINIGMVSGVLPVMGSPLPFFSYGGSAIITQGAIFGMIMSLNLRKPSIVEQSRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2X2</accession>
    <name>D0Z2X2_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Maltose/maltodextrin transport system permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">VDA_000773</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">The complex is composed of two ATP-binding proteins (MalK), two transmembrane proteins (MalG and MalF) and a solute-binding protein (MalE).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell inner membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000773"/>
    <dbReference type="EnsemblBacteria" id="EEZ39753">
        <property type="protein sequence ID" value="EEZ39753"/>
        <property type="gene ID" value="VDA_000773"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1619224at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030156">
        <property type="entry name" value="MalF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035277">
        <property type="entry name" value="MalF_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029345">
        <property type="entry name" value="MalF_P2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47314:SF1">
        <property type="entry name" value="PTHR47314:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14785">
        <property type="entry name" value="MalF_P2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="6 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="57"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="84"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="297"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="332"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="388"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="443"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="501"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="298"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU367050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EEZ39753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="531" mass="58570" checksum="81FB1983E2C31AAC" modified="2010-01-19" version="1">MQSHQAADMTLESPVGDMSVGIKKDSQNKKWLKWLALGLISIINGYATILMYARGEYAFALLTLVLTSLGVYVFARKSMYAHRYIFPGVAGMILFIIFPLMYTIGLAFTNYSGTNQLSLERAQSVLLQQTYQSGDSVKFSLYDDNGKVHIALQEGNKWYQTPAYDLKQLPTEPISLTEVAVPSGDKAPLKQVIANRKALSDITLIGAEGNNLKMSGLRTFAEIEPVYTLEKDGETLINHQKEITLKPNMDIGFYQQVDANGQFVGEPLSPGFIVNIGWDNFSRIFNDPGIQQPFFKIFVWTVVFSALTVILTLAVGVVLAQIVSWEELKGRGVYRLLLILPYAVPAFISILIFKGLFNQSFGEINQVLEGLFGISPAWFTDPFLAKTMLIIVNTWLGYPYMMILAMGLLKAIPDDLYEASAMDGAGPIDNFFKITLPLLVKPMIPLLIASFAFNFNNFVLIQLLTNGAPDMIGTSVPAGHTDLLVSYTYRVAFEGAGGQDFGLAGAIATLIFLLVGGLSLLNMKFTKLESE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z2Z5</accession>
    <name>D0Z2Z5_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000796</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305375.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39776">
        <property type="protein sequence ID" value="EEZ39776"/>
        <property type="gene ID" value="VDA_000796"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG5031N0U">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1764991at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005669774" evidence="1">
        <location>
            <begin position="19"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="210" mass="23533" checksum="2870F97F75BDC109" modified="2010-01-19" version="1">MKLLVLFFSLLLYGCASGMKVSVPDSYTEVSTARGYLVGVIGASAIWPQTGENLKTTIELRKLLPDGSKGEPILLTNDNKQHDFATPAQTGQLFTLLLPEGEYDISKVTIEGSDGNRSFISTNQDDLNIHFTVRSNQISYIGEFIAVSHVAESQLWNMEYPSGKGYLVHNYAENRDQPLFYELNPNLKEIVFHTEKLGQMNFNFLQSVMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z378</accession>
    <name>D0Z378_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cadherin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000879</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000879"/>
    <dbReference type="EnsemblBacteria" id="EEZ39859">
        <property type="protein sequence ID" value="EEZ39859"/>
        <property type="gene ID" value="VDA_000879"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2931">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002126">
        <property type="entry name" value="Cadherin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043824">
        <property type="entry name" value="DUF5801"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018511">
        <property type="entry name" value="Hemolysin-typ_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001343">
        <property type="entry name" value="Hemolysn_Ca-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019959">
        <property type="entry name" value="T1SS-143_rpt-cont_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19116">
        <property type="entry name" value="DUF5801"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00353">
        <property type="entry name" value="HemolysinCabind"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51120">
        <property type="entry name" value="SSF51120"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03660">
        <property type="entry name" value="T1SS_rpt_143"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50268">
        <property type="entry name" value="CADHERIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00330">
        <property type="entry name" value="HEMOLYSIN_CALCIUM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cadherin" evidence="3">
        <location>
            <begin position="7125"/>
            <end position="7250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="5291"/>
            <end position="5334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="5492"/>
            <end position="5512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="5304"/>
            <end position="5332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="7833" mass="812667" checksum="F7D3B700CFC3D787" modified="2010-01-19" version="1">[encoded data, 7833 characters]</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3A3</accession>
    <name>D0Z3A3_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative regulatory protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_000904</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000904"/>
    <dbReference type="EnsemblBacteria" id="EEZ39884">
        <property type="protein sequence ID" value="EEZ39884"/>
        <property type="gene ID" value="VDA_000904"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1349">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014036">
        <property type="entry name" value="DeoR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001034">
        <property type="entry name" value="DeoR_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018356">
        <property type="entry name" value="Tscrpt_reg_HTH_DeoR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00455">
        <property type="entry name" value="DeoRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08220">
        <property type="entry name" value="HTH_DeoR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00037">
        <property type="entry name" value="HTHLACR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00420">
        <property type="entry name" value="HTH_DEOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00894">
        <property type="entry name" value="HTH_DEOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51000">
        <property type="entry name" value="HTH_DEOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH deoR-type" evidence="4">
        <location>
            <begin position="18"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="262" mass="28885" checksum="25E33C88BE92A254" modified="2010-01-19" version="1">MKGRGIIIPLPFSELNVMNKRRNEILQMVNHRKRIQVSELSEIIGVSGVTIRQDLNFLEKEGYLKRIHGAAVVNHVDDIDTRLEICFDVKQSLAIKAADLVTPNETVLIEGGSANALLARLLAERGDVTIITPSAYIAHLIRNTSANVILLGGVYQHHGESLVGPLTKLCIENINFSTAFLGVDGFHQDTGFTSRDMMRAEIASVILTKNRRNIVLTDSSKFGQIYPSTIGKTNNINILVTDSGISDGDLTFFKNNNVEVIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3I8</accession>
    <name>D0Z3I8_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Dipeptidase</fullName>
            <ecNumber evidence="4">3.4.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_000989</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>an L-aminoacyl-L-amino acid + H2O = 2 an L-alpha-amino acid</text>
            <dbReference type="Rhea" id="RHEA:48940"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:59869"/>
            <dbReference type="ChEBI" id="CHEBI:77460"/>
            <dbReference type="EC" id="3.4.13.19"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the peptidase C69 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005305922.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39969">
        <property type="protein sequence ID" value="EEZ39969"/>
        <property type="gene ID" value="VDA_000989"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4690">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="414486at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070004">
        <property type="term" value="F:cysteine-type exopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016805">
        <property type="term" value="F:dipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005322">
        <property type="entry name" value="Peptidase_C69"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12994">
        <property type="entry name" value="PTHR12994"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03577">
        <property type="entry name" value="Peptidase_C69"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0224">Dipeptidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003020043" description="Dipeptidase" evidence="5">
        <location>
            <begin position="23"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ39969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="490" mass="54851" checksum="9B15471B85AD886B" modified="2010-01-19" version="1">MKKLTLLASSIIAATIAGQASACTTILVGNQATKDGSYIVARNEDYQATNAKNFVFHPAEKPQKEAFHSNANDFTYPAAKEALQYTSMSDFNTDGKSMGEVGFNSAGVGMSSTETIYNGAKALKVDPYVTKTGIGEDSIENVILPRIHSAKEGVELLGKIIETQGASEGFGVAFVDNDGIWYLETGSGHQWMAEKVPADKYFVSANQGRLQHYLPNNPNYLASPTLVSFAEQHGLYQAVKGQPFDFHAAYSQDTPNDITYNYPRVWTLQHMYTQGLKTKIDQGKTFPVFLKPTHKLTVADVEQGLRNHYQGTSHDPYANKNPKEPYRPVSVFRTQESHVLQVRPNLPKAIGEVEYMAYGMTSLSVYLPYYQGMTKVPHSITLGTDQADDQSANWKFRKLQTLAMMDWNDFAPIVQKAYQNFEQQTAQKQKEMEKQYLAIYKSEPKQAQALINNFEQQTVTDVLKLTDQLTNTLFTKLTHKVDMTYHFEGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3Q2</accession>
    <name>D0Z3Q2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hypothetical arginase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_001053</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the arginase family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306093.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001053"/>
    <dbReference type="EnsemblBacteria" id="EEZ40033">
        <property type="protein sequence ID" value="EEZ40033"/>
        <property type="gene ID" value="VDA_001053"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0010">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1598732at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016813">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006035">
        <property type="entry name" value="Ureohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11358">
        <property type="entry name" value="PTHR11358"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00491">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036979">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00116">
        <property type="entry name" value="ARGINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="SSF52768"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51409">
        <property type="entry name" value="ARGINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ40033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="323" mass="36023" checksum="FC90CC80102CFA5E" modified="2010-01-19" version="1">MFVDHLKRLFMSEQIEHKTASSRMFITPYAQQRERGIVLLGVVSDLSLGFHRSRDEAKDGPESIRQVLPKIHTHGHLPVYDAGNIELEQSHFTAVAQQQYLTLCELLQQGQLPVVLGGGHEISVASYQAVSDVMAQLHHIDKTTTETDIAQCVRVGVINFDAHFELRPALSMKPGSAFHMAANYSREKGREFNYLGLGICEHANSQAMFKLADELGCRWLLDNQMTTRNKKKVQAVLDGFIDSVDHIHLSVDMDVFSSTVAPAANMTNMGGVSLSVVEWALKYIMESGKVKLVDLAELNPEFDYEHRTAKLAGKLVHAIARNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3T0</accession>
    <name>D0Z3T0_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative tagatose-6-phosphate ketose/aldose isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_001081</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>D-galactosamine 6-phosphate + H2O = D-tagatopyranose 1-phosphate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:47680"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:71674"/>
            <dbReference type="ChEBI" id="CHEBI:138150"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the SIS family. AgaS subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306174.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001081"/>
    <dbReference type="EnsemblBacteria" id="EEZ40061">
        <property type="protein sequence ID" value="EEZ40061"/>
        <property type="gene ID" value="VDA_001081"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2222">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1046291at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901135">
        <property type="term" value="P:carbohydrate derivative metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05010">
        <property type="entry name" value="SIS_AgaS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05008">
        <property type="entry name" value="SIS_GlmS_GlmD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035466">
        <property type="entry name" value="GlmS/AgaS_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035464">
        <property type="entry name" value="SIS_AgaS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014180">
        <property type="entry name" value="Sugar_isomerase_AgaS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01380">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02815">
        <property type="entry name" value="agaS_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="SIS" evidence="5">
        <location>
            <begin position="49"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="5">
        <location>
            <begin position="219"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ40061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="390" mass="43051" checksum="499510869092F194" modified="2010-01-19" version="1">MNSYLGYTEQELNRLKGYWTAKEITQQPECWLQTLQIVQECRPAIKAFMDKVFAHQNIRIVLTGAGTSAFAGKSLAPTLTEQLSCRVEAIATTDIVSNPKQYFAEDIPTLLVSFARSGNSPESVAAVELANQCLSQCYHLVLTCNNEGELYKNSINNENALPLLMPEQTNDKSFAMTSSFSSMMLACLSVMLYGNDYTKGFESVCRDSVQSLKDFDSKIRNTINHEVDRVIYLGSGGLQGLAQESSLKLLELTAGKVVACYDSPLGFRHGPKSIVNEKTLVVVFVSNDEYTRKYDLDLLNELRRDNIAFDVIAIAAQPDPRIESGTHFYVDKMAGATDAGLLFPYMLFAQSYAFHCSLALGNTPDNPCPTGEVNRVVQGVVIHDLSGNLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-12-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z3W4</accession>
    <name>D0Z3W4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Non-specific DNA-binding protein Dps/iron-binding ferritin-like antioxidant protein/ferroxidase</fullName>
            <ecNumber evidence="3">1.16.3.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_001117</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Dps family.</text>
    </comment>
    <dbReference type="EC" id="1.16.3.1" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ40095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_001117"/>
    <dbReference type="EnsemblBacteria" id="EEZ40095">
        <property type="protein sequence ID" value="EEZ40095"/>
        <property type="gene ID" value="VDA_001117"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0783">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004322">
        <property type="term" value="F:ferroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002177">
        <property type="entry name" value="DPS_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008331">
        <property type="entry name" value="Ferritin_DPS_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42932">
        <property type="entry name" value="PTHR42932"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00210">
        <property type="entry name" value="Ferritin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ferritin" evidence="2">
        <location>
            <begin position="2"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ40095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="95" mass="11162" checksum="E06FF4E02554F414" modified="2010-01-19" version="1">MTDDIAERVRKIGGRTIHSIGHIARLQRIEDNDADYVDPQDMLAELCEDNKHLASELRMAHTLCDGFNDFSSVSMIDDWIDQTERRVWFLYESYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z433</accession>
    <name>D0Z433_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter ATPase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_000289</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005303953.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000289"/>
    <dbReference type="EnsemblBacteria" id="EEZ39271">
        <property type="protein sequence ID" value="EEZ39271"/>
        <property type="gene ID" value="VDA_000289"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1120">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1752365at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="3"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="35"/>
            <end position="42"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="264" mass="29923" checksum="C76046E44D89FBCD" modified="2010-01-19" version="1">MLFNCQHLSYSIDERHILRNVSLQLSAGESVALLGTNGAGKSTLLKLMLGILTPQSGKIELHNKPLNQWRRRDIAKHIAYVPQQHSPHFPYTVEQVIEQGCLPQAGLFRVITTEQKQLIEQAMIQMDVMSLRARNYTQLSGGERQRTLLARALVQQTPIILLDEPTNGLDYGSQLRLLMLLKEIAHSGRTILTITHNPEHALMFSDRAIALHQGEIIADGRPHQVIDTQLIHQLYGLSVNQLDFTEGRFFTPFYSQNNNTKDFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-09-29" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z448</accession>
    <name>D0Z448_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Urease accessory protein UreE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VDA_000304</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000304"/>
    <dbReference type="EnsemblBacteria" id="EEZ39286">
        <property type="protein sequence ID" value="EEZ39286"/>
        <property type="gene ID" value="VDA_000304"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2371">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065003">
        <property type="term" value="P:protein-containing complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019627">
        <property type="term" value="P:urea metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012406">
        <property type="entry name" value="UreE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007864">
        <property type="entry name" value="UreE_C_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05194">
        <property type="entry name" value="UreE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036402">
        <property type="entry name" value="Ureas_acces_UreE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0533">Nickel</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UreE_C" evidence="4">
        <location>
            <begin position="17"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EEZ39286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="94" mass="10338" checksum="EC09C1A9E02D1CD3" modified="2010-01-19" version="1">MVAAESGETAIIIAAKETVSTVITEDPLLLARVCYHLGNRHVPLQVEQGWCRYQHDHVLDDMVRGLGAQVIVEQEKYQPEPGAYGGTTGGHHHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2021-04-07" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z450</accession>
    <name>D0Z450_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Urease subunit gamma</fullName>
            <ecNumber evidence="3">3.5.1.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000306</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 3">
            <text>2 H(+) + H2O + urea = CO2 + 2 NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:20557"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16199"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.1.5"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the urease gamma subunit family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.5" evidence="3"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000306"/>
    <dbReference type="EnsemblBacteria" id="EEZ39288">
        <property type="protein sequence ID" value="EEZ39288"/>
        <property type="gene ID" value="VDA_000306"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0831">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009039">
        <property type="term" value="F:urease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043419">
        <property type="term" value="P:urea catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00390">
        <property type="entry name" value="Urease_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002026">
        <property type="entry name" value="Urease_gamma/gamma-beta_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036463">
        <property type="entry name" value="Urease_gamma_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00547">
        <property type="entry name" value="Urease_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54111">
        <property type="entry name" value="SSF54111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00193">
        <property type="entry name" value="urease_gam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="57" mass="6245" checksum="5279FA3B7BB91C2B" modified="2010-01-19" version="1">MEGARDGKTVAELMNFGRTILTADDVMEGIPEMIPNIQVECTFPDGTKLVSIHEPII</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z453</accession>
    <name>D0Z453_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VDA_000309</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000309"/>
    <dbReference type="EnsemblBacteria" id="EEZ39291">
        <property type="protein sequence ID" value="EEZ39291"/>
        <property type="gene ID" value="VDA_000309"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0601">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="106"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="142"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="180"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="244"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="285"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="102"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EEZ39291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="320" mass="35564" checksum="A71AD2E13585D686" modified="2010-01-19" version="1">MSVMNQCWWKQTLLHSMAQFGAVIALVFIIIKFSPLDPVNQFLGGNVASVSVEQKQLIAEHLGANQGYFERLLIWGEDVLLHGGGYSNLYQQSVSDVIGHYLPHSLILMGVSWLLILILGYSFGVVSAYYQDSVVDKWLCRIAWCVSSIPSFWLGLVFLSLFAIKLQWLPLARLEEGSNIVSLSLVLPLVTLVFTSIPNIYLHTREKTVAVLQSDYIQYAKAHQLPFAHLVRFYIFPNSFTPALLLQLTSLAELISGSVMIETVFNYPGLGHVFLQACLASDVALLAALTCFAAGLVLMGNLLACFLQYRLMPSCRANLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z467</accession>
    <name>D0Z467_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000323</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304044.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39305">
        <property type="protein sequence ID" value="EEZ39305"/>
        <property type="gene ID" value="VDA_000323"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502ZC6N">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1700639at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025368">
        <property type="entry name" value="DUF4272"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14094">
        <property type="entry name" value="DUF4272"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="207" mass="23347" checksum="20655419EBA1BBE4" modified="2010-01-19" version="1">MDLQKIRKKSLSSAEKLGYEINTILPLFDDGIKLRPQEEIVGRSLALFAVVACSYGFDKPSAIQWMVREGVIDYLSDSERSFLNDGEGDISFFQSQVEGLNAFAWALGFVKSIPFDSTCDNTLIKRFPDIKNDKSSSEYKTQSAVRSIAQIISACDLAYCLHWAIVNAEVNIQDLHGDVGRHVISERRRALEWILCTDDWDEISLDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z490</accession>
    <name>D0Z490_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative Cold shock-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000346</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304109.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000346"/>
    <dbReference type="EnsemblBacteria" id="EEZ39328">
        <property type="protein sequence ID" value="EEZ39328"/>
        <property type="gene ID" value="VDA_000346"/>
    </dbReference>
    <dbReference type="GeneID" id="57343274"/>
    <dbReference type="eggNOG" id="COG1278">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2034748at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04458">
        <property type="entry name" value="CSP_CDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012156">
        <property type="entry name" value="Cold_shock_CspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011129">
        <property type="entry name" value="CSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019844">
        <property type="entry name" value="CSD_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002059">
        <property type="entry name" value="CSP_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00313">
        <property type="entry name" value="CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002599">
        <property type="entry name" value="Cold_shock_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00050">
        <property type="entry name" value="COLDSHOCK"/>
    </dbReference>
    <dbReference type="SMART" id="SM00357">
        <property type="entry name" value="CSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00352">
        <property type="entry name" value="CSD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51857">
        <property type="entry name" value="CSD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CSD" evidence="3">
        <location>
            <begin position="3"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="69" mass="7466" checksum="DE8804454FE50A18" modified="2010-01-19" version="1">MSKATGTVKWFNEEKGFGFITQDNGGADVFVHFRAITGEGFKTLAEGQKVTFDIEQGQKGPQAANVEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-01-19" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4C2</accession>
    <name>D0Z4C2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative DNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VDA_000378</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304198.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000378"/>
    <dbReference type="EnsemblBacteria" id="EEZ39360">
        <property type="protein sequence ID" value="EEZ39360"/>
        <property type="gene ID" value="VDA_000378"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2964">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1474443at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039446">
        <property type="entry name" value="DauR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039445">
        <property type="entry name" value="DauR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013559">
        <property type="entry name" value="YheO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35568">
        <property type="entry name" value="PTHR35568"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13309">
        <property type="entry name" value="HTH_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08348">
        <property type="entry name" value="PAS_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAS_6" evidence="1">
        <location>
            <begin position="21"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="HTH_22" evidence="2">
        <location>
            <begin position="164"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EEZ39360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="225" mass="25132" checksum="ADCEEF55838CB627" modified="2010-01-19" version="1">MSTKTLDSLATKFSDRDKEILTSYFRLADTIADFIGPHSEVVIHSFENFEKSVVKIVNGHHTGRTLGSPITDLGLRMLSAYEKTGEVTPKSYFTQSKDGSLLKSTTCILMGENNRPIGMFCINMNLSFPFPEIIKTLMPDMGHSTMAVSENFSSCANDVIDHALDHAITEIENDVSINLKGRNKAITKLLFENGIFELKEATAIVSDRLGITRHAIYKYLREFKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4C4</accession>
    <name>D0Z4C4_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative diaminopropionate ammonia-lyase</fullName>
            <ecNumber evidence="4">4.3.1.15</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VDA_000380</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">CIP 102761</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="4.3.1.15" evidence="4"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304204.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000380"/>
    <dbReference type="EnsemblBacteria" id="EEZ39362">
        <property type="protein sequence ID" value="EEZ39362"/>
        <property type="gene ID" value="VDA_000380"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1171">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1876944at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008838">
        <property type="term" value="F:diaminopropionate ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010081">
        <property type="entry name" value="DiNH2opropionate_NH3_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019871">
        <property type="entry name" value="DiNH2propionate_NH3-lyase_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03528">
        <property type="entry name" value="2_3_DAP_am_ly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01747">
        <property type="entry name" value="diampropi_NH3ly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PALP" evidence="3">
        <location>
            <begin position="35"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EEZ39362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="389" mass="41768" checksum="F73D6E35266ADD6D" modified="2010-01-19" version="1">MLKVSQNSYFSGQTSPLFTQEMAKETRTFHQKIEGYSPTPLVSLPNLAQLFGVKSILVKDESKRFGLNAFKVLGGSYALGQALAEHLNVDINDIDLKTVASKLEQPLVFTTATAGNHGTGVAWAAREMGQKAVVYMPKGSPQASVERIRGLGAECIVTDVNYDDTVRLANKTAEENGWMLVQDTAWEGYEQIPTWISQGYMTMADEALEQAIALAEQPTHIMLQAGVGAMAGGVLGYFADALGSDKFTAIIGEPAAADCIYRSGIKGEMENVSGDLTSIMAGLACGEPNPVTWPILRDCSHSFISAKDEVAALGMRILGNPLAGDSVVTSGESGALSMGILHQLITTEDGRQQAEKMGLNRDSVIMIFSTEGDTNPERYRRIVWTGSAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4F9</accession>
    <name>D0Z4F9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Excinuclease ABC subunit B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_000415</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304305.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000415"/>
    <dbReference type="EnsemblBacteria" id="EEZ39397">
        <property type="protein sequence ID" value="EEZ39397"/>
        <property type="gene ID" value="VDA_000415"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0556">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="95696at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009380">
        <property type="term" value="C:excinuclease repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004807">
        <property type="entry name" value="UvrB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041471">
        <property type="entry name" value="UvrB_inter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024759">
        <property type="entry name" value="UvrB_YAD/RRR_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24029">
        <property type="entry name" value="PTHR24029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12344">
        <property type="entry name" value="UvrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17757">
        <property type="entry name" value="UvrB_inter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00631">
        <property type="entry name" value="uvrb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0227">DNA damage</keyword>
    <keyword evidence="2" id="KW-0228">DNA excision</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3" id="KW-0267">Excision nuclease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="5">
        <location>
            <begin position="27"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="6">
        <location>
            <begin position="432"/>
            <end position="596"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="650" mass="74128" checksum="E7A597E743DFCE59" modified="2010-01-19" version="1">MSYNSFILHSDYSPSGDQVEAIAKLVDGVESGASHQVLQGITGSGKTFTMANVIHRLKRPTLILAHNKTLAAQLYSEMKRFFPENHVEYFVSYYDFYQPEVYIPASDRFIRKDSAINEQLERLRLSTTKALIEQRDVIVVASVSAIYGLGEPELYRAAQIPLYIGRKINRSQFIEQLTSLQYQRTEKRLERATFRSHGDIVDIFPAESEKVAIRVEMLDDEIEQLYWLDPFSGKTLGALERYRVSPKTLYAASKDKITKASLLIQKDLEQRVAQLNQENRITEAARLYERTMYDIEMMQQLGYCSGLENYSCYLNDRDPTLPPTTLLDYLPKDGLLFIDESHVMIPQISAMFKGDQSRKETLIEYGFRLPSAKNNRPLDFNEFEKIKPQTLFVSATPGNYELSKAKTPVVEQIIRPTGLLDPTIEVRSSSNQISNLLDEIKIRIEKGERTLVNTLTKKSAESLYEYMQEQSFKVSYLHSDVKTEDRVRIIEQLRAGELDILIGINLLREGLDIPEASLVAILDADHAGFLRSKAALIQIIGRAARNKNGMAILYGNKVTPAMQQAIDESLDRRSRQIQYNHLHQINPITSIRQELVTSSSSANPEFCTNLAQLCQQITDTEKLLLSLPEGENSESIRTKLDGLYRQFIYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4G7</accession>
    <name>D0Z4G7_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Aspartokinase</fullName>
            <ecNumber evidence="10">2.7.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">VDA_000423</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">CIP 102761</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>ATP + L-aspartate = 4-phospho-L-aspartate + ADP</text>
            <dbReference type="Rhea" id="RHEA:23776"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57535"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 1/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="11">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 1/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="11">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 1/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the aspartokinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.4" evidence="10"/>
    <dbReference type="EMBL" id="ADBS01000002">
        <property type="protein sequence ID" value="EEZ39405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005304327.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000423"/>
    <dbReference type="EnsemblBacteria" id="EEZ39405">
        <property type="protein sequence ID" value="EEZ39405"/>
        <property type="gene ID" value="VDA_000423"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0527">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1067792at2"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00015"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00461"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00462"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004072">
        <property type="term" value="F:aspartate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005260">
        <property type="entry name" value="Asp_kin_monofn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001341">
        <property type="entry name" value="Asp_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042199">
        <property type="entry name" value="AsparK_Bifunc_asparK/hSer_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018042">
        <property type="entry name" value="Aspartate_kinase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000726">
        <property type="entry name" value="Asp_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00657">
        <property type="entry name" value="asp_kinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00324">
        <property type="entry name" value="ASPARTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 10 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AA_kinase" evidence="12">
        <location>
            <begin position="3"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="8"/>
            <end position="11"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="222"/>
            <end position="223"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000726-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EEZ39405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="449" mass="48896" checksum="3BAE8F2B8A572467" modified="2010-01-19" version="1">MKKVTVAKFGGTSVADFAAMMNSATIVRNNPDTRLVVISACSGVTNILVELANGVADVDRRSALIKQLTHIHFAIFEQLSPCTETAIKVSELIDNIAFLSESAAQHTHDQLSDQMVACGELLSTFVFTHLMKDLGMPAVRFDVRDVMCTNSHFGQAEPNLEAIQTLSAQYLLPLLKDHVVVTQGFIGADNHNYTTTLGRGGSDYSAALLAEAIDAETLEIWTDVPGIYSTDPRVAPNAMPIAEISFKEASEMANFGAKILHPATLIPAMRKQVPVFVGSSKEPHRGGTWIRQAANTEPIFRAIALRSNQALVTLNNIHSVHNSGFLAQVFAILAKHNVSVDLMTTSDGCLSLTLNQATTRGGLPQLPFEVEQELSLLCQVKIENNLSLIALIGNKMDEKHGTCSQIFSSLEPYNLQMICYGASEHSLCFLADENSSSEIVQTLHRRIFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4W1</accession>
    <name>D0Z4W1_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type III secretion system effector delivery regulator TyeA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000194</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000194"/>
    <dbReference type="EnsemblBacteria" id="EEZ39178">
        <property type="protein sequence ID" value="EEZ39178"/>
        <property type="gene ID" value="VDA_000194"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG50331IZ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015144">
        <property type="entry name" value="T3SS_TyeA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013351">
        <property type="entry name" value="T3SS_TyeA-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038347">
        <property type="entry name" value="TyeA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09059">
        <property type="entry name" value="TyeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02511">
        <property type="entry name" value="type_III_tyeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TyeA" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="62" mass="7456" checksum="A9FF89BC88305499" modified="2010-01-19" version="1">MELASTEQKISFFRELHKLIRHIPIDVFNDEEQRQNLIQAVQKALDEAIDLEEEEMWDDELD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z4Y9</accession>
    <name>D0Z4Y9_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ISPsy3 transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VDA_000222</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000222"/>
    <dbReference type="EnsemblBacteria" id="EEZ39206">
        <property type="protein sequence ID" value="EEZ39206"/>
        <property type="gene ID" value="VDA_000222"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0517">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007069">
        <property type="entry name" value="Transposase_32"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04986">
        <property type="entry name" value="Y2_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EEZ39206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="233" mass="28041" checksum="0CB757ED9033CE24" modified="2010-01-19" version="1">MSFAKKRGIEIGLFCVVHTFGRQLNWNVHFHLSVTRGGINNKTKRWGNIYFNAAMVEQHWKQQVVSFLRDHYHNLNTKHDNYQHIRDFRGWSQFLSSQYSRKWRIHFAYKDHRDNCYKALVLSQIEMIDRLVSHIPVEKNFRAIRYYGFLSNRKRGEALPLVYDLLDQEEPVKPKPLNYAQMMHHQVRIDPYKCILCGGRMFFVKMEMGLKVHELVALRKATIREKRRLRYSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z509</accession>
    <name>D0Z509_PHODD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mutator family transposase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VDA_000242</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">CIP 102761</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">Required for the transposition of the insertion element.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the transposase mutator family.</text>
    </comment>
    <dbReference type="EMBL" id="ADBS01000003">
        <property type="protein sequence ID" value="EEZ39226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005306708.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000003.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="EEZ39226">
        <property type="protein sequence ID" value="EEZ39226"/>
        <property type="gene ID" value="VDA_000242"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3328">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="792870at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001207">
        <property type="entry name" value="Transposase_mutator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33217">
        <property type="entry name" value="PTHR33217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00872">
        <property type="entry name" value="Transposase_mut"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01007">
        <property type="entry name" value="TRANSPOSASE_MUTATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0814">Transposable element</keyword>
    <keyword evidence="4 6" id="KW-0815">Transposition</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EEZ39226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="402" mass="46590" checksum="AA5855CEBD1BD1D9" modified="2010-01-19" version="1">MDKKALEAFAREAAKSIKTESDLDDFRKMLTKVTVETALNAELDEHLGYQKHQARTSSNSRNGYSGKSIITDDGEVDIEIPRDREASFEPQLIRKHQTRFQSMDDKILSLYAKGMTTREIVATFKEMYDADVSPTLISKVTDSVLEQVIEWQSRPLDEVYPIVYLDCIVIKVRQDKQVINKAVYLALGVNMEGQKELLGMWLSETEGAKFWLNVLTELQNRGVKDILIACVDGLKGFPDAINTVFPETQIQLCIVHMVRNSVKYVPWKDYRAVTADLKKIYQSTTEDEALLALEQFSARWDSKYPQISRSWTTHWNNLNTLFNYPEDIRRAIYTTNAIESLNSVIRKAIKKRKLFPTDESARKVIYLAIRDASKKWTMPIRNWRQALNRFIIMFEDRLSEYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2020-10-07" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>D0Z5G2</accession>
    <name>D0Z5G2_PHODD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VDA_000069</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Photobacterium damselae subsp. damselae CIP 102761</name>
        <dbReference type="NCBI Taxonomy" id="675817"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Vibrionales</taxon>
            <taxon>Vibrionaceae</taxon>
            <taxon>Photobacterium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Los Alamos National Laboratory (LANL)"/>
                <consortium name="National Microbial Pathogen Data Resource (NMPDR)"/>
                <person name="Munk A.C."/>
                <person name="Tapia R."/>
                <person name="Green L."/>
                <person name="Rogers Y."/>
                <person name="Detter J.C."/>
                <person name="Bruce D."/>
                <person name="Brettin T.S."/>
                <person name="Colwell R."/>
                <person name="Huq A."/>
                <person name="Grim C.J."/>
                <person name="Hasan N.A."/>
                <person name="Vonstein V."/>
                <person name="Bartels D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">CIP 102761</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="ADBS01000006">
        <property type="protein sequence ID" value="EEZ39014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_005307145.1">
        <property type="nucleotide sequence ID" value="NZ_ADBS01000006.1"/>
    </dbReference>
    <dbReference type="STRING" id="675817.VDA_000069"/>
    <dbReference type="EnsemblBacteria" id="EEZ39014">
        <property type="protein sequence ID" value="EEZ39014"/>
        <property type="gene ID" value="VDA_000069"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0388">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1583074at2"/>
    <dbReference type="Proteomes" id="UP000003579">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="SSF56317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="1">
        <location>
            <begin position="6"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EEZ39014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000003579"/>
        </source>
    </evidence>
    <sequence length="252" mass="27538" checksum="5C58128C4C6DE86D" modified="2010-01-19" version="1">MESGKIRFALAQHKAIKGNIKENLNRHKQFCSKAAQLGADIITFPELSLTGYEPSLLNDLAIDMSSTHVHELSQFAVSNSIVVIAGCPIKSGQSKPYIGAIICHPSGEVDFYSKQYLHQGESEFCVAGSVNYFFNVNKIKIALAVCADFTEPRHQSDAFTEKAVVYLVSALISKEGFSQDSALLSRIAIKIRTPVLLSNFLGKTGDWDTAGKCSVWDKEGNAVVQGSPSEEGLTLCTIENDIIYDINFQPID</sequence>
</entry>
<copyright>
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms Distributed under the Creative Commons Attribution (CC BY 4.0) License
</copyright>
</uniprot>